# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Aminotran_5 PF00266.14 EDN90601.1 - 4.1e-07 29.0 0.0 4.7e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN90601.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ELFV_dehydrog PF00208.16 EDN90602.1 - 3.1e-31 108.8 0.2 4.1e-28 98.6 0.1 2.5 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EDN90602.1 - 2.6e-22 78.2 0.1 1.5e-16 59.1 0.0 3.0 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EDN90602.1 - 0.0076 15.8 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tmemb_161AB PF10268.4 EDN90603.1 - 0.19 10.1 0.1 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Fe-S_biosyn PF01521.15 EDN90604.1 - 8.7e-11 41.7 0.1 1.5e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 EDN90605.1 - 3.6e-26 90.9 16.2 6.6e-26 90.1 11.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EDN90605.1 - 9.5e-19 66.7 1.3 9.5e-19 66.7 0.9 2.3 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e RCC1 PF00415.13 EDN90606.1 - 6.8e-38 128.6 12.5 7.6e-11 42.0 0.0 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN90606.1 - 1.9e-29 100.5 24.7 2.4e-07 30.1 1.6 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EDN90607.1 - 7e-52 176.0 1.5 3e-32 111.7 0.0 2.1 1 1 1 2 2 2 2 Rad9 LRR_4 PF12799.2 EDN90608.1 - 0.0085 15.6 18.2 5.8 6.6 0.1 6.1 2 2 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EDN90608.1 - 0.055 13.5 13.3 7.1 7.0 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat Abhydrolase_6 PF12697.2 EDN90609.1 - 1.8e-27 96.7 0.0 2.1e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN90609.1 - 2e-15 56.9 0.0 1.3e-08 34.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN90609.1 - 2.2e-15 56.6 0.0 3.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN90609.1 - 7.4e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EDN90609.1 - 8.7e-06 26.1 0.0 1.2e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.8 EDN90609.1 - 0.024 14.0 0.0 0.064 12.6 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 EDN90609.1 - 0.025 14.1 0.0 0.098 12.2 0.0 1.8 1 1 1 2 2 2 0 Serine hydrolase Lipase_3 PF01764.20 EDN90609.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EDN90609.1 - 0.087 12.3 0.1 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EDN90609.1 - 0.089 11.6 0.0 0.54 9.0 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EDN90609.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 EDN90609.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase RF-1 PF00472.15 EDN90610.1 - 1e-24 86.5 3.7 1.1e-24 86.3 2.1 1.4 1 1 0 1 1 1 1 RF-1 domain Cwf_Cwc_15 PF04889.7 EDN90610.1 - 0.0028 17.4 10.8 0.0044 16.7 7.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 EDN90610.1 - 0.17 11.4 10.9 0.25 10.8 7.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MIR PF02815.14 EDN90610.1 - 0.35 10.3 5.6 1 8.8 3.9 1.7 1 1 0 1 1 1 0 MIR domain PBP1_TM PF14812.1 EDN90610.1 - 3.5 7.9 9.7 9 6.6 6.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3317 PF11779.3 EDN90611.1 - 1.9e-24 84.8 5.9 2.6e-24 84.4 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) QueT PF06177.6 EDN90611.1 - 0.034 14.1 0.3 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 QueT transporter Peptidase_U4 PF03419.8 EDN90611.1 - 0.51 9.3 6.3 0.71 8.8 4.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CENP-I PF07778.6 EDN90612.1 - 6.7e-43 146.6 3.2 9.4e-34 116.4 0.3 3.2 1 1 2 3 3 3 3 Mis6 Ribosomal_S21 PF01165.15 EDN90613.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein S21 Acetyltransf_1 PF00583.19 EDN90614.1 - 1.8e-08 34.2 0.0 5.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN90614.1 - 0.002 18.2 0.0 0.029 14.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN90614.1 - 0.01 15.9 0.0 0.56 10.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain HAD_2 PF13419.1 EDN90616.1 - 8.5e-19 68.4 0.0 1e-16 61.6 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN90616.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EDN90618.1 - 1.7e-50 171.6 0.1 7.4e-50 169.5 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN90618.1 - 2.6e-28 98.7 0.1 5.5e-27 94.4 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN90618.1 - 2.4e-09 36.5 0.0 5.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN90618.1 - 0.022 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltransf PF01255.14 EDN90618.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase GIDA PF01134.17 EDN90619.1 - 3.5e-158 526.5 0.0 4.4e-158 526.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EDN90619.1 - 3.7e-15 55.7 0.0 9.1e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EDN90619.1 - 1.5e-08 34.7 0.9 4e-08 33.3 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN90619.1 - 4.9e-07 29.1 0.5 8.2e-07 28.4 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EDN90619.1 - 3.7e-06 26.0 1.3 0.0038 16.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN90619.1 - 0.0026 16.6 2.3 0.0026 16.6 1.6 2.4 3 1 1 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.16 EDN90619.1 - 0.017 14.6 0.2 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EDN90619.1 - 0.095 12.7 0.2 0.87 9.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN90619.1 - 0.11 10.9 5.9 0.18 10.2 0.7 2.5 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 EDN90619.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Aa_trans PF01490.13 EDN90620.1 - 2.6e-30 105.2 15.2 3.2e-30 104.9 10.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3321 PF11968.3 EDN90622.1 - 7.1e-92 306.9 0.0 9e-92 306.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EDN90622.1 - 0.031 14.0 0.0 0.06 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EDN90622.1 - 0.047 13.3 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Ribosomal_L23eN PF03939.8 EDN90623.1 - 2.2e-19 69.1 8.7 2.2e-19 69.1 6.1 2.4 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EDN90623.1 - 3e-16 59.1 1.6 3e-16 59.1 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 EDN90624.1 - 2.7e-23 81.0 3.1 3.6e-23 80.6 2.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.13 EDN90625.1 - 6.2e-33 114.0 0.0 9.3e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 EDN90626.1 - 1.8e-27 94.9 0.0 2.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EDN90626.1 - 0.033 14.5 0.1 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF1201 PF06716.6 EDN90626.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) zf-rbx1 PF12678.2 EDN90627.1 - 1.1e-35 121.5 13.7 1.4e-35 121.2 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN90627.1 - 3.3e-17 62.1 10.0 4.2e-17 61.7 6.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EDN90627.1 - 1.9e-07 30.8 12.1 1.2e-06 28.2 8.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN90627.1 - 0.0013 18.3 11.8 0.022 14.4 8.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN90627.1 - 0.002 17.7 9.5 0.28 10.8 6.8 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN90627.1 - 0.042 13.8 13.0 0.043 13.8 5.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EDN90627.1 - 0.47 10.4 9.3 2.4 8.1 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EDN90627.1 - 0.85 9.3 6.9 0.94 9.2 1.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EDN90627.1 - 0.91 9.3 12.2 8.7 6.1 8.5 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EDN90627.1 - 2 8.5 10.8 1.1e+02 3.0 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PNRC PF15365.1 EDN90628.1 - 2.9e-06 27.1 4.8 2.9e-06 27.1 3.3 3.9 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator CDP-OH_P_transf PF01066.16 EDN90629.1 - 1.8e-17 63.4 5.3 2.7e-17 62.9 3.7 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Ytp1 PF10355.4 EDN90629.1 - 0.095 11.8 0.2 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) Gti1_Pac2 PF09729.4 EDN90631.1 - 2.5e-59 199.9 0.0 3.2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family CRISPR_Cas2 PF09827.4 EDN90632.1 - 0.12 12.5 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Tyr-DNA_phospho PF06087.7 EDN90633.1 - 1.1e-07 30.8 1.4 0.0053 15.4 0.0 3.5 2 1 2 4 4 4 3 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EDN90633.1 - 0.015 14.7 0.1 0.015 14.7 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin interaction motif Suc_Fer-like PF06999.7 EDN90634.1 - 2.1e-06 27.9 0.0 2.2e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Plant_vir_prot PF01307.12 EDN90634.1 - 0.029 14.1 0.0 0.032 13.9 0.0 1.2 1 1 0 1 1 1 0 Plant viral movement protein Suc_Fer-like PF06999.7 EDN90635.1 - 1.7e-29 103.4 0.0 2e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2823 PF11034.3 EDN90636.1 - 6.2e-35 119.1 13.5 7e-35 118.9 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Activator-TraM PF11657.3 EDN90636.1 - 1.2 8.5 4.2 1.6 8.2 2.9 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM EBP PF05241.7 EDN90637.1 - 3.3e-67 225.2 14.0 3.8e-67 225.0 9.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein MARVEL PF01284.18 EDN90638.1 - 9.9e-06 25.4 16.3 3.4e-05 23.6 11.6 1.6 1 1 1 2 2 2 2 Membrane-associating domain CD20 PF04103.10 EDN90638.1 - 0.099 12.5 0.0 0.099 12.5 0.0 2.5 2 1 1 3 3 3 0 CD20-like family TMEMspv1-c74-12 PF11044.3 EDN90638.1 - 0.11 12.1 8.2 0.11 12.0 0.0 2.7 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF3938 PF13074.1 EDN90638.1 - 0.21 11.4 3.8 0.37 10.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF2975 PF11188.3 EDN90638.1 - 0.69 9.6 6.5 24 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SUR7 PF06687.7 EDN90638.1 - 5.5 6.4 13.0 0.47 9.9 0.6 2.5 1 1 0 2 2 2 0 SUR7/PalI family Pec_lyase_C PF00544.14 EDN90640.1 - 4.6e-22 78.4 1.8 6.8e-22 77.9 1.2 1.3 1 0 0 1 1 1 1 Pectate lyase Abhydrolase_3 PF07859.8 EDN90641.1 - 7.2e-32 110.6 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN90641.1 - 0.00047 18.9 0.0 0.00079 18.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EDN90641.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDN90641.1 - 0.0025 17.7 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN90641.1 - 0.0043 16.8 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDN90641.1 - 0.0072 14.8 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EDN90641.1 - 0.035 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.13 EDN90641.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribonuclease_T2 PF00445.13 EDN90644.1 - 1.8e-26 92.9 3.2 2.6e-14 53.2 0.0 2.5 2 1 1 3 3 3 2 Ribonuclease T2 family Porphobil_deam PF01379.15 EDN90647.1 - 3e-83 277.9 0.0 3.9e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EDN90647.1 - 3.1e-17 62.4 0.0 6.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.14 EDN90648.1 - 2.6e-30 104.5 0.1 3.1e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ras PF00071.17 EDN90649.1 - 1.3e-20 73.3 0.0 1.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN90649.1 - 1.3e-13 51.5 0.1 2.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN90649.1 - 3.7e-06 26.2 0.1 4.9e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN90649.1 - 0.00016 20.8 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EDN90649.1 - 0.00017 20.4 0.6 0.13 10.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EDN90649.1 - 0.055 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1590 PF07629.6 EDN90649.1 - 0.056 13.0 5.0 0.14 11.7 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) RWD PF05773.17 EDN90649.1 - 0.12 12.2 0.3 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 RWD domain Pex14_N PF04695.8 EDN90649.1 - 2.3 8.2 12.3 55 3.8 8.5 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PLAC8 PF04749.12 EDN90650.1 - 8.1e-10 39.2 0.0 2.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 PLAC8 family DUF3499 PF12005.3 EDN90651.1 - 4.8 7.3 6.7 14 5.8 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) Daxx PF03344.10 EDN90651.1 - 6.7 5.0 37.8 11 4.3 26.2 1.3 1 0 0 1 1 1 0 Daxx Family TIP120 PF08623.5 EDN90652.1 - 2.3e-65 219.3 2.9 4.1e-64 215.2 0.2 3.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EDN90652.1 - 2.1e-14 53.5 31.4 0.031 14.5 1.4 10.2 8 2 3 11 11 11 7 HEAT repeats HEAT PF02985.17 EDN90652.1 - 1.6e-10 40.1 13.5 0.45 10.7 0.0 11.0 12 0 0 12 12 12 3 HEAT repeat DUF2435 PF10363.4 EDN90652.1 - 1e-05 25.3 3.9 2.8 7.9 0.0 6.8 6 0 0 6 6 6 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EDN90652.1 - 6.3e-05 22.8 1.4 0.13 12.1 0.0 4.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EDN90652.1 - 0.0064 16.8 0.2 3.9 7.9 0.0 5.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDN90652.1 - 0.019 15.4 35.5 2.8 8.5 0.3 12.9 11 2 2 13 13 13 0 HEAT-like repeat GTP_EFTU PF00009.22 EDN90653.1 - 1.1e-59 201.0 0.1 1.5e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN90653.1 - 4.2e-27 94.1 0.6 2e-26 92.0 0.0 2.3 2 1 1 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN90653.1 - 1.6e-17 63.3 2.5 4.5e-17 61.9 1.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN90653.1 - 2.2e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDN90653.1 - 0.00032 20.2 0.4 0.00078 19.0 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EDN90653.1 - 0.0011 19.3 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EDN90653.1 - 0.031 13.7 0.3 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Abhydrolase_4 PF08386.5 EDN90654.1 - 4.4e-17 61.8 0.0 9.1e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EDN90654.1 - 4.1e-14 52.7 0.1 3.1e-08 33.4 0.0 4.0 4 0 0 4 4 4 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN90654.1 - 2.6e-07 30.7 0.0 1.2e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN90654.1 - 0.0051 16.5 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family MerR PF00376.18 EDN90654.1 - 0.13 11.8 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein Methyltransf_23 PF13489.1 EDN90656.1 - 6.9e-14 51.8 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN90656.1 - 1.6e-11 44.5 0.0 2.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN90656.1 - 2.5e-10 40.9 0.0 7.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN90656.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN90656.1 - 7.9e-09 35.9 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDN90656.1 - 2.5e-08 33.3 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EDN90656.1 - 9.7e-08 32.3 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN90656.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN90656.1 - 0.00021 20.7 0.0 0.00033 20.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EDN90656.1 - 0.00033 19.8 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.13 EDN90656.1 - 0.0004 19.7 0.0 0.07 12.4 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EDN90656.1 - 0.00087 18.4 0.0 0.0015 17.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 EDN90656.1 - 0.0012 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 EDN90656.1 - 0.0022 17.4 0.0 0.0056 16.1 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 EDN90656.1 - 0.0025 17.3 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EDN90656.1 - 0.024 14.2 0.0 0.062 12.9 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.7 EDN90656.1 - 0.048 13.0 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EDN90656.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_PK PF05891.7 EDN90656.1 - 0.16 11.2 0.0 0.4 9.9 0.0 1.6 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Abhydrolase_3 PF07859.8 EDN90657.1 - 5.5e-26 91.4 0.0 1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN90657.1 - 3e-19 68.8 0.0 4.5e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDN90657.1 - 0.0005 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EDN90657.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DEAD PF00270.24 EDN90658.1 - 1.1e-41 142.0 0.0 4.7e-41 140.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN90658.1 - 1e-26 92.5 0.1 3.7e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN90658.1 - 6.9e-07 28.3 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDN90658.1 - 0.0001 22.2 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 EDN90659.1 - 2.9e-60 203.6 0.0 3.4e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN90659.1 - 3.7e-35 121.2 0.0 5e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN90659.1 - 4.2e-08 32.4 0.0 6.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Methyltransf_23 PF13489.1 EDN90660.1 - 4.2e-09 36.3 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN90660.1 - 0.0021 18.6 0.0 0.0054 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN90660.1 - 0.015 15.7 0.0 5 7.6 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDN90660.1 - 0.056 12.4 0.0 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase ABM PF03992.11 EDN90661.1 - 4.3e-11 42.6 0.0 5.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4358 PF14270.1 EDN90661.1 - 0.032 14.1 1.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) DUF1235 PF06822.7 EDN90661.1 - 0.06 12.3 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) SAD_SRA PF02182.12 EDN90662.1 - 5.2e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain RasGEF_N_2 PF14663.1 EDN90662.1 - 0.014 15.3 0.1 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MAT1 PF06391.8 EDN90662.1 - 0.04 13.5 0.3 0.082 12.4 0.2 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TruD PF01142.13 EDN90663.1 - 4.3e-55 186.9 0.0 1.5e-50 171.9 0.0 3.8 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) CDO_I PF05995.7 EDN90664.1 - 1.4e-31 109.0 0.0 1.6e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EDN90664.1 - 1.6e-05 24.3 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Rotamase PF00639.16 EDN90665.1 - 0.0001 22.9 0.0 0.00013 22.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.21 EDN90666.1 - 2.6e-28 97.3 1.1 3.3e-28 97.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EDN90666.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ribosomal_S8 PF00410.14 EDN90667.1 - 3.8e-24 84.9 0.1 5.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.7 EDN90668.1 - 6.5e-19 67.8 8.5 7.5e-16 57.8 5.3 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3328 PF11807.3 EDN90668.1 - 0.022 14.4 0.2 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DEAD PF00270.24 EDN90671.1 - 7.6e-46 155.6 0.0 4.2e-44 150.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN90671.1 - 1.6e-28 98.3 0.0 3.8e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN90671.1 - 4.6e-05 23.3 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDN90671.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EDN90671.1 - 0.016 13.6 0.0 0.78 8.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Phos_pyr_kin PF08543.7 EDN90672.1 - 2.4e-70 236.5 0.2 3.1e-70 236.1 0.2 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EDN90672.1 - 2.2e-15 57.0 0.1 8.1e-15 55.1 0.1 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EDN90672.1 - 2.1e-12 46.7 0.1 3.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EDN90672.1 - 0.0034 16.6 0.8 0.0083 15.4 0.6 1.8 1 1 0 1 1 1 1 Carbohydrate kinase DOMON PF03351.12 EDN90674.1 - 0.00019 21.3 1.9 0.00042 20.2 0.5 2.0 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.11 EDN90674.1 - 0.004 16.9 12.3 0.0088 15.8 8.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.4 EDN90674.1 - 0.025 14.7 11.4 0.29 11.2 0.9 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF2427 PF10348.4 EDN90674.1 - 0.47 10.0 5.1 3.7 7.1 3.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) SUR7 PF06687.7 EDN90675.1 - 0.15 11.5 0.3 0.19 11.2 0.2 1.1 1 0 0 1 1 1 0 SUR7/PalI family PUF PF00806.14 EDN90679.1 - 3.1e-57 186.9 16.6 1.4e-08 33.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Repressor_Mnt PF11423.3 EDN90679.1 - 0.073 12.4 0.8 0.18 11.1 0.2 1.9 2 0 0 2 2 2 0 Regulatory protein Mnt SapB_2 PF03489.12 EDN90679.1 - 0.23 11.5 0.3 17 5.5 0.0 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 2 EAP30 PF04157.11 EDN90687.1 - 6.6e-63 211.8 0.0 7.5e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.14 EDN90688.1 - 6.2e-40 136.2 0.4 7.1e-40 136.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PDH PF02153.12 EDN90689.1 - 2.4e-13 49.5 0.0 3.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EDN90689.1 - 9.7e-08 32.0 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDN90689.1 - 2.6e-06 27.7 0.0 5.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EDN90689.1 - 0.00014 21.3 0.0 0.00036 20.0 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EDN90689.1 - 0.0002 20.5 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDN90689.1 - 0.0027 17.3 0.0 0.0073 15.9 0.0 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDN90689.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EDN90689.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.1 EDN90689.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Ribosomal_S11 PF00411.14 EDN90690.1 - 1.5e-40 137.8 0.5 1.8e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EDN90690.1 - 0.035 13.0 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) AAR2 PF05282.6 EDN90691.1 - 2.1e-72 244.0 0.0 4e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 AAR2 protein DUF2217 PF10265.4 EDN90692.1 - 0.035 12.8 1.4 0.041 12.6 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) zf-MIZ PF02891.15 EDN90692.1 - 0.14 11.7 2.0 5.2 6.6 0.7 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DAP10 PF07213.6 EDN90692.1 - 0.17 11.6 0.2 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 DAP10 membrane protein eIF-3c_N PF05470.7 EDN90693.1 - 5.3e-175 582.9 21.9 3.8e-142 474.4 1.4 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EDN90693.1 - 1.6e-13 50.8 2.7 3.8e-13 49.6 0.0 2.9 3 0 0 3 3 3 1 PCI domain DUF4363 PF14276.1 EDN90693.1 - 0.68 9.6 4.8 4.5 7.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) Daxx PF03344.10 EDN90693.1 - 3.6 5.9 25.7 6.4 5.1 17.8 1.4 1 0 0 1 1 1 0 Daxx Family SNF2_N PF00176.18 EDN90696.1 - 1.8e-68 230.5 0.0 3.3e-68 229.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN90696.1 - 2.3e-15 56.2 0.0 6.4e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN90696.1 - 0.0071 15.8 0.0 0.11 12.0 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EDN90696.1 - 0.033 13.7 3.7 0.2 11.1 0.0 3.4 2 1 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EDN90696.1 - 3.1 5.5 5.7 4.8 4.9 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EDN90698.1 - 2.4e-43 148.1 0.1 1.7e-33 115.8 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN90698.1 - 1.3e-16 60.4 0.7 3.3e-11 42.7 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EDN90698.1 - 0.0012 18.6 1.3 0.0017 18.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN90698.1 - 0.074 12.3 0.0 0.28 10.4 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EDN90698.1 - 0.089 12.3 0.4 0.54 9.7 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF4430 PF14478.1 EDN90698.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Glyco_transf_8 PF01501.15 EDN90699.1 - 1.5e-18 67.0 1.6 3.1e-18 66.0 1.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDN90699.1 - 0.061 12.6 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Hemerythrin PF01814.18 EDN90700.1 - 1.7e-11 44.4 4.6 2.6e-11 43.8 3.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_11 PF13414.1 EDN90701.1 - 1.9e-15 56.2 1.8 8.3e-10 38.1 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDN90701.1 - 3.1e-15 55.0 5.0 3e-07 29.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDN90701.1 - 6e-14 50.7 3.6 1.1e-05 24.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN90701.1 - 2.1e-08 33.3 2.7 0.00021 20.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN90701.1 - 5e-08 32.7 0.2 5.1e-05 23.1 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat PB1 PF00564.19 EDN90701.1 - 3.2e-07 29.9 0.3 5.9e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 EDN90701.1 - 3.4e-07 29.5 0.1 1.1e-05 24.9 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN90701.1 - 1.2e-05 25.4 0.1 7.9 7.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN90701.1 - 0.00041 20.9 0.2 0.014 16.0 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN90701.1 - 0.00051 20.0 0.1 0.035 14.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN90701.1 - 0.0083 15.9 0.1 3.2 7.6 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN90701.1 - 0.015 15.8 0.0 0.21 12.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sod_Cu PF00080.15 EDN90702.1 - 8.1e-13 48.7 0.1 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EDN90702.1 - 2.7e-12 46.6 0.1 4.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_L13 PF00572.13 EDN90703.1 - 9.1e-39 132.4 0.0 1.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 zf-C2H2_4 PF13894.1 EDN90704.1 - 0.00077 19.6 5.7 0.12 12.7 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN90704.1 - 0.0027 17.9 7.8 0.35 11.2 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN90704.1 - 5.4 7.4 11.8 8.5 6.8 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Uricase PF01014.13 EDN90706.1 - 6e-87 288.7 0.5 6.7e-46 155.7 0.4 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EDN90707.1 - 1.3e-142 474.7 2.5 6.5e-142 472.5 0.4 2.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EDN90707.1 - 6.4e-56 188.8 1.0 5.5e-54 182.5 0.1 3.7 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EDN90707.1 - 7.7e-42 141.8 1.5 1.6e-40 137.6 0.0 3.6 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EDN90707.1 - 2.9e-31 107.1 0.4 1.1e-29 102.0 0.0 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EDN90707.1 - 1.1e-15 57.1 5.1 1.1e-15 57.1 3.6 2.1 2 0 0 2 2 2 1 Hr1 repeat HEAT_2 PF13646.1 EDN90707.1 - 5.3e-06 26.6 1.9 0.2 11.9 0.0 5.4 6 0 0 6 6 6 2 HEAT repeats MIF4G PF02854.14 EDN90708.1 - 2.8e-52 177.1 0.1 4.5e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EDN90708.1 - 1.9e-24 85.3 1.0 7.3e-24 83.4 0.7 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 EDN90708.1 - 0.15 11.9 0.4 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Extensin_2 PF04554.8 EDN90710.1 - 5.7 6.8 17.0 2.4 8.1 8.5 2.2 2 0 0 2 2 2 0 Extensin-like region MFMR PF07777.6 EDN90712.1 - 1.5 8.6 3.3 2.6 7.9 2.3 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR PBP PF01161.15 EDN90713.1 - 4.7e-17 62.1 0.0 6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GDA1_CD39 PF01150.12 EDN90714.1 - 5.2e-97 325.0 0.0 6.5e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.6 EDN90715.1 - 2.2e-37 128.3 0.0 3.2e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EDN90715.1 - 3.2e-24 85.4 1.3 3e-13 49.7 0.0 2.5 1 1 1 2 2 2 2 PPPDE putative peptidase domain Thioredoxin PF00085.15 EDN90715.1 - 2.6e-12 46.3 0.0 5.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 EDN90715.1 - 6.6e-05 22.5 0.0 0.00093 18.7 0.0 2.1 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 EDN90715.1 - 0.00081 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EDN90715.1 - 0.0012 19.0 0.2 0.0054 16.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 EDN90715.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_8 PF13905.1 EDN90715.1 - 0.028 14.5 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 EDN90715.1 - 0.065 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin p450 PF00067.17 EDN90719.1 - 6e-35 120.6 0.0 8e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EDN90720.1 - 4.8e-24 84.7 16.8 9.5e-24 83.7 11.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 EDN90721.1 - 1.5e-49 168.8 0.0 2.2e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 ATP-grasp_4 PF13535.1 EDN90722.1 - 3.3e-24 85.6 0.0 1.3e-21 77.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN90722.1 - 5.3e-05 22.6 0.0 0.00048 19.5 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EDN90722.1 - 8.1e-05 21.5 0.0 0.05 12.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EDN90722.1 - 0.014 15.2 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.14 EDN90722.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain APH PF01636.18 EDN90725.1 - 3.9e-12 46.4 0.0 5.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN90725.1 - 4.6e-05 23.0 0.1 0.0001 21.9 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EDN90725.1 - 0.043 13.1 0.1 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family N_Asn_amidohyd PF14736.1 EDN90725.1 - 0.069 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Kdo PF06293.9 EDN90725.1 - 0.073 12.1 0.0 2.3 7.2 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_1 PF03184.14 EDN90727.1 - 2e-45 154.6 0.4 1.5e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN90727.1 - 2.5e-12 46.1 0.5 5.6e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN90727.1 - 1.1e-09 37.9 0.3 4e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN90727.1 - 9.9e-09 35.0 0.1 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EDN90727.1 - 0.025 14.7 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HTH_28 PF13518.1 EDN90727.1 - 0.033 14.1 0.4 0.24 11.4 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN90727.1 - 0.11 12.2 0.3 0.69 9.6 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_S21e PF01249.13 EDN90728.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S21e VWA PF00092.23 EDN90732.1 - 2.2e-07 30.7 0.0 4.6e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EDN90732.1 - 0.00023 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EDN90732.1 - 0.00053 20.1 0.0 0.0022 18.1 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF605 PF04652.11 EDN90732.1 - 0.39 10.0 12.0 0.52 9.6 8.3 1.1 1 0 0 1 1 1 0 Vta1 like HSP70 PF00012.15 EDN90734.1 - 1.3e-262 872.0 7.3 1.6e-262 871.8 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN90734.1 - 2.7e-17 62.3 0.1 3.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDN90734.1 - 0.0014 18.2 0.1 0.0086 15.7 0.0 2.2 2 1 1 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EDN90734.1 - 0.0036 16.4 0.6 0.019 14.1 0.0 2.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 EDN90734.1 - 0.046 12.6 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 EDN90734.1 - 0.047 13.5 4.1 2 8.2 0.4 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DUF4404 PF14357.1 EDN90734.1 - 7.4 7.0 8.5 21 5.6 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WWbp PF10349.4 EDN90737.1 - 9.7e-21 74.8 3.0 3.9e-20 72.8 0.2 2.1 2 0 0 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EDN90737.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.5 1 1 0 1 1 1 0 GRAM domain UCR_hinge PF02320.11 EDN90738.1 - 2.5e-28 97.8 5.6 4.6e-28 96.9 3.9 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein SCHIP-1 PF10148.4 EDN90738.1 - 0.034 13.5 1.3 0.04 13.2 0.9 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 BSP_II PF05432.6 EDN90738.1 - 0.24 10.6 15.9 0.29 10.3 11.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 EDN90738.1 - 1 7.1 8.3 1.2 6.9 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.3 EDN90738.1 - 1 8.2 6.4 1.2 8.1 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pox_Ag35 PF03286.9 EDN90738.1 - 2.2 7.7 12.6 2.7 7.4 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 EDN90738.1 - 3.6 6.4 5.4 4.1 6.3 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 EDN90738.1 - 3.7 6.8 16.5 4.5 6.5 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2360 PF10152.4 EDN90738.1 - 4 7.7 9.8 5 7.3 6.8 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Daxx PF03344.10 EDN90738.1 - 4 5.8 18.8 4.5 5.6 13.1 1.1 1 0 0 1 1 1 0 Daxx Family NARP1 PF12569.3 EDN90738.1 - 5.8 5.5 9.8 7.1 5.2 6.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP1_TM PF14812.1 EDN90738.1 - 6.2 7.2 7.8 8.9 6.6 5.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2413 PF10310.4 EDN90738.1 - 8.5 5.0 11.8 10 4.8 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MFS_1 PF07690.11 EDN90739.1 - 4.7e-26 91.3 34.4 6.9e-26 90.7 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OMPdecase PF00215.19 EDN90740.1 - 9e-91 303.2 0.0 1.1e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_6 PF03737.10 EDN90741.1 - 3.4e-20 72.4 0.2 4.6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase ATP_bind_3 PF01171.15 EDN90744.1 - 1e-18 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EDN90744.1 - 0.0015 18.8 0.0 0.004 17.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EDN90744.1 - 0.002 17.4 1.3 0.002 17.4 0.9 3.5 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 EDN90744.1 - 0.055 12.0 0.0 0.096 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 EDN90744.1 - 0.77 9.5 6.7 0.44 10.2 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L7Ae PF01248.21 EDN90745.1 - 8.7e-21 73.2 0.9 1.5e-20 72.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDN90745.1 - 0.0054 16.5 0.1 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Pro_CA PF00484.14 EDN90746.1 - 2.3e-46 157.5 0.5 3.1e-46 157.1 0.4 1.2 1 0 0 1 1 1 1 Carbonic anhydrase OCD_Mu_crystall PF02423.10 EDN90747.1 - 4.4e-13 48.6 1.5 1e-06 27.7 0.2 2.9 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EDN90747.1 - 0.0076 16.3 0.0 0.05 13.7 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.16 EDN90748.1 - 8.7e-65 218.3 0.1 1.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EDN90749.1 - 1.1e-40 139.5 0.0 1.5e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN90751.1 - 6.4e-26 90.8 0.0 9.6e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YTH PF04146.10 EDN90752.1 - 1.8e-37 128.0 0.0 5.8e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 YT521-B-like domain Mannosyl_trans2 PF04188.8 EDN90753.1 - 2.5e-36 125.5 5.1 3e-25 89.0 0.6 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 EDN90755.1 - 1.5e-33 114.3 0.0 4.2e-33 112.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) AAA_10 PF12846.2 EDN90755.1 - 0.0098 15.3 0.0 0.074 12.4 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain ParcG PF10274.4 EDN90755.1 - 0.013 15.4 0.2 2.3 8.0 0.0 3.1 2 1 0 2 2 2 0 Parkin co-regulated protein HEAT PF02985.17 EDN90755.1 - 0.048 13.7 1.5 2.3 8.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Velvet PF11754.3 EDN90756.1 - 1e-36 126.4 4.0 1.8e-36 125.6 0.2 2.7 2 1 0 2 2 2 1 Velvet factor NTP_transferase PF00483.18 EDN90764.1 - 1.7e-48 165.1 0.0 1.9e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EDN90764.1 - 1.1e-10 41.8 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 EDN90764.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase DND1_DSRM PF14709.1 EDN90767.1 - 0.00013 22.1 0.1 0.00031 20.9 0.1 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EDN90767.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Prenyltrans PF00432.16 EDN90769.1 - 1.3e-29 101.4 21.0 2.9e-09 36.3 0.2 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDN90769.1 - 3.6e-22 78.9 0.0 6.8e-16 58.6 0.0 4.2 1 1 3 4 4 4 4 Prenyltransferase-like Zn_clus PF00172.13 EDN90770.1 - 0.0026 17.6 7.7 0.006 16.4 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 EDN90770.1 - 0.37 9.7 0.2 0.72 8.7 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus BMRF2 protein ubiquitin PF00240.18 EDN90771.1 - 4.6e-137 445.5 21.3 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EDN90771.1 - 2.3e-77 254.6 21.2 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN90771.1 - 1e-23 83.4 9.5 0.00017 21.7 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN90771.1 - 1.7e-20 73.3 0.7 0.002 17.8 0.0 4.1 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN90771.1 - 1.9e-13 50.2 3.2 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN90771.1 - 2.9e-13 49.8 1.6 0.15 12.2 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDN90771.1 - 6.1e-10 39.0 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EDN90771.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EDN90771.1 - 7.8e-07 28.4 0.5 0.99 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EDN90771.1 - 3.4e-06 26.8 4.5 6.4 6.7 0.0 4.2 4 0 0 4 4 4 3 GLUT4 regulating protein TUG ACT_4 PF13291.1 EDN90771.1 - 0.00081 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 EDN90771.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EDN90771.1 - 0.0054 15.1 13.5 3.9 5.6 0.2 5.5 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EDN90771.1 - 0.01 15.9 4.9 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EDN90771.1 - 0.015 15.1 14.0 5.7 6.9 0.2 4.6 1 1 3 4 4 4 0 DnaJ C terminal domain GABP-alpha PF11620.3 EDN90771.1 - 0.018 15.0 7.5 17 5.4 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EDN90771.1 - 0.027 14.3 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif CDC48_2 PF02933.12 EDN90771.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 FERM_N PF09379.5 EDN90771.1 - 2.1 8.4 12.5 86 3.2 0.1 5.7 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EDN90771.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) DUF3244 PF11589.3 EDN90771.1 - 9 6.0 8.2 1.6e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3244) BRAP2 PF07576.7 EDN90772.1 - 1.3e-22 79.4 0.0 2.2e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EDN90772.1 - 4.3e-17 61.9 7.0 1.3e-16 60.3 4.9 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EDN90772.1 - 4.7e-09 35.9 9.7 4.7e-09 35.9 6.7 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN90772.1 - 4.1e-05 23.1 7.2 4.1e-05 23.1 5.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN90772.1 - 0.00024 20.7 7.9 0.00024 20.7 5.5 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN90772.1 - 0.0008 19.0 6.7 0.0008 19.0 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN90772.1 - 0.00087 19.2 8.5 0.00087 19.2 5.9 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN90772.1 - 0.0011 19.0 5.1 0.0011 19.0 3.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EDN90772.1 - 0.0068 16.1 3.1 0.032 14.0 2.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EDN90772.1 - 0.0074 15.9 1.0 0.0074 15.9 0.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDN90772.1 - 0.033 14.0 6.3 0.089 12.6 4.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FlaC_arch PF05377.6 EDN90772.1 - 1.3 8.9 3.7 11 6.0 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prok-RING_4 PF14447.1 EDN90772.1 - 5.2 6.6 9.8 27 4.3 0.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3129 PF11327.3 EDN90773.1 - 7.6e-58 195.3 13.2 7.6e-58 195.3 9.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) Period_C PF12114.3 EDN90773.1 - 2.3 7.7 8.8 4.5 6.8 6.1 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2201_N PF13203.1 EDN90773.1 - 6.9 5.7 7.7 12 4.9 5.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Helicase_C PF00271.26 EDN90775.1 - 0.046 13.5 0.0 0.051 13.4 0.0 1.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain 2OG-FeII_Oxy PF03171.15 EDN90776.1 - 7.2e-14 51.8 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN90776.1 - 1.6e-07 31.8 0.0 2.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RRM_2 PF04059.7 EDN90780.1 - 2.1e-38 130.2 0.2 3.7e-38 129.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EDN90780.1 - 0.0014 18.2 0.1 0.15 11.7 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN90780.1 - 0.0035 17.2 0.3 0.14 12.1 0.0 3.2 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 EDN90782.1 - 1.7e-89 300.2 15.3 3.8e-85 285.9 0.9 3.4 2 2 1 3 3 3 2 Exocyst complex subunit Sec15-like COG5 PF10392.4 EDN90782.1 - 0.0017 18.3 7.1 0.013 15.4 2.9 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4201 PF13870.1 EDN90782.1 - 0.0094 15.4 6.7 0.023 14.1 4.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Mnd1 PF03962.10 EDN90782.1 - 0.028 14.0 4.4 1.6 8.4 2.2 2.9 2 0 0 2 2 2 0 Mnd1 family COG2 PF06148.6 EDN90782.1 - 0.11 12.3 7.7 0.048 13.5 2.5 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IZUMO PF15005.1 EDN90782.1 - 0.48 10.4 4.4 24 4.9 0.1 4.3 3 2 1 4 4 4 0 Izumo sperm-egg fusion Mod_r PF07200.8 EDN90782.1 - 1.6 8.6 12.9 1.4 8.8 4.2 3.4 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Sec8_exocyst PF04048.9 EDN90782.1 - 4.9 6.7 16.6 0.54 9.8 4.4 4.1 4 1 1 5 5 5 0 Sec8 exocyst complex component specific domain CBFD_NFYB_HMF PF00808.18 EDN90783.1 - 1.8e-19 69.5 0.6 2.6e-19 69.0 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN90783.1 - 3.3e-11 43.1 0.1 5.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EDN90783.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 EDN90785.1 - 4.5e-33 113.2 0.5 4.5e-33 113.2 0.4 2.0 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 EDN90786.1 - 2.5e-23 81.7 0.0 4.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.20 EDN90787.1 - 1.5e-41 142.4 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ras PF00071.17 EDN90788.1 - 3.2e-35 120.8 0.2 3.2e-35 120.8 0.1 1.8 2 0 0 2 2 2 1 Ras family tRNA-synt_2b PF00587.20 EDN90788.1 - 3.8e-30 104.7 0.1 1.3e-29 102.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDN90788.1 - 6.2e-18 64.7 6.6 6.2e-18 64.7 4.6 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Miro PF08477.8 EDN90788.1 - 3.4e-06 27.5 0.0 1.3e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDN90788.1 - 0.00069 19.1 0.2 0.0014 18.1 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EDN90788.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family WAPL PF07814.8 EDN90789.1 - 2e-22 79.3 0.5 3.2e-22 78.7 0.4 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Nucleoplasmin PF03066.10 EDN90789.1 - 0.013 15.0 3.2 0.032 13.7 2.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF506 PF04720.7 EDN90789.1 - 0.1 12.2 1.3 0.32 10.5 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Sigma70_ner PF04546.8 EDN90789.1 - 0.16 11.5 5.8 0.47 10.0 4.0 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 EDN90789.1 - 0.47 10.1 2.4 1.4 8.5 1.6 1.8 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.7 EDN90789.1 - 1.2 8.8 14.9 0.017 14.8 3.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 EDN90789.1 - 7.4 6.9 13.2 0.39 11.0 3.3 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPRTase PF14681.1 EDN90790.1 - 2e-79 265.5 0.0 2.7e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EDN90790.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EDN90790.1 - 0.056 13.1 0.1 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EDN90791.1 - 9.4e-27 92.5 3.1 1.2e-26 92.2 2.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like GTP_CH_N PF12471.3 EDN90792.1 - 1.5e-86 289.0 0.0 2.1e-86 288.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EDN90792.1 - 5.6e-06 25.6 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.16 EDN90792.1 - 0.0084 15.5 0.0 1.4 8.3 0.0 2.8 3 0 0 3 3 3 2 Bacterial regulatory proteins, gntR family 2-Hacid_dh_C PF02826.14 EDN90794.1 - 1.4e-50 170.8 0.0 5.2e-50 169.0 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN90794.1 - 2.6e-35 120.7 0.0 4.4e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN90794.1 - 2e-05 24.4 0.3 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EDN90794.1 - 0.00023 21.0 0.1 0.00077 19.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EDN90794.1 - 0.004 16.5 0.1 0.066 12.5 0.0 2.4 2 1 1 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EDN90794.1 - 0.028 14.0 0.5 0.93 9.1 0.2 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.20 EDN90794.1 - 0.039 13.4 0.1 0.19 11.2 0.1 2.3 1 1 0 1 1 1 0 ACT domain Ribosomal_S3Ae PF01015.13 EDN90795.1 - 7.2e-82 273.4 6.0 8.8e-82 273.1 4.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 EDN90795.1 - 0.057 13.7 0.8 0.14 12.5 0.0 2.1 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain Ras PF00071.17 EDN90796.1 - 4.5e-48 162.6 0.0 5.3e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN90796.1 - 1.2e-17 64.4 0.0 1.6e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN90796.1 - 1.1e-12 47.4 0.0 1.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN90796.1 - 5.6e-05 22.4 0.0 6.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDN90796.1 - 0.00014 21.3 0.0 0.00043 19.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN90796.1 - 0.00018 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDN90796.1 - 0.0076 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EDN90796.1 - 0.0081 15.6 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN90796.1 - 0.022 14.8 0.0 0.039 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN90796.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN90796.1 - 0.029 14.3 0.0 0.071 13.0 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EDN90796.1 - 0.042 13.0 0.0 0.097 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN90796.1 - 0.048 13.1 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EDN90796.1 - 0.052 12.6 0.0 0.24 10.5 0.0 1.9 1 1 0 1 1 1 0 AIG1 family ABC_tran PF00005.22 EDN90796.1 - 0.067 13.4 0.1 0.093 13.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Abhydrolase_6 PF12697.2 EDN90797.1 - 2.1e-13 50.7 0.0 7.8e-10 39.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN90797.1 - 7.6e-10 38.7 0.0 9.1e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN90797.1 - 1.3e-06 28.1 0.0 0.015 15.0 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN90797.1 - 0.00075 19.1 0.0 0.65 9.5 0.0 2.2 2 0 0 2 2 2 2 PGAP1-like protein NCA2 PF08637.5 EDN90797.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 Peptidase_C78 PF07910.8 EDN90798.1 - 1.5e-69 233.4 0.0 2e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-RAG1 PF10426.4 EDN90798.1 - 0.11 12.4 0.3 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Pkinase PF00069.20 EDN90799.1 - 1.5e-64 217.7 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN90799.1 - 4.7e-31 107.8 0.0 6.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN90799.1 - 0.00053 19.0 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like P5-ATPase PF12409.3 EDN90801.1 - 1.7e-37 127.8 0.0 3.7e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter CMAS PF02353.15 EDN90801.1 - 6.2e-36 123.8 1.3 8.5e-36 123.4 0.2 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase HAD PF12710.2 EDN90801.1 - 5.9e-32 111.3 0.1 3e-31 109.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN90801.1 - 6.3e-25 87.5 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN90801.1 - 1.2e-15 58.4 0.0 1.3e-13 51.9 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.1 EDN90801.1 - 1e-14 54.4 0.0 2.1e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN90801.1 - 1.5e-14 54.2 0.0 3.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN90801.1 - 5.5e-13 48.9 0.0 1.5e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN90801.1 - 2.5e-10 40.6 0.0 8e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN90801.1 - 2.8e-09 37.5 0.0 7.8e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN90801.1 - 1.7e-07 30.5 0.0 3.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EDN90801.1 - 4.4e-07 30.2 0.0 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN90801.1 - 7.7e-06 25.3 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Cation_ATPase_C PF00689.16 EDN90801.1 - 0.00023 20.7 4.8 0.00052 19.5 3.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF938 PF06080.7 EDN90801.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Hydrolase_3 PF08282.7 EDN90801.1 - 0.015 14.9 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN90801.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Methyltransf_4 PF02390.12 EDN90801.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EDN90801.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cation_ATPase_N PF00690.21 EDN90801.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus NAP PF00956.13 EDN90802.1 - 1e-88 296.6 12.9 1e-88 296.6 8.9 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Myosin_head PF00063.16 EDN90804.1 - 1.1e-220 734.2 0.0 1.9e-220 733.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EDN90804.1 - 1.1e-34 118.4 3.4 2.8e-34 117.1 2.3 1.8 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EDN90804.1 - 5.3e-15 53.5 33.7 0.0002 20.7 0.5 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EDN90804.1 - 0.0012 18.9 0.0 0.0051 16.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN90804.1 - 0.011 15.6 0.3 0.073 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EDN90804.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EDN90804.1 - 0.074 12.2 1.0 0.16 11.1 0.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EDN90804.1 - 0.4 10.7 10.3 2.5 8.2 7.1 2.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 EDN90804.1 - 0.54 10.1 10.6 0.1 12.5 0.4 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) APH PF01636.18 EDN90806.1 - 0.12 12.1 0.2 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family p450 PF00067.17 EDN90807.1 - 1e-20 73.7 0.0 4.5e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ham1p_like PF01725.11 EDN90808.1 - 5.1e-20 71.6 0.0 5.6e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EDN90809.1 - 9.6e-30 103.5 0.1 9.6e-30 103.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN90809.1 - 7e-17 62.3 4.5 3.6e-16 60.0 3.2 1.9 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EDN90809.1 - 1.6e-07 31.3 0.1 3.7e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EDN90809.1 - 5.5e-06 26.3 0.2 0.00034 20.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDN90809.1 - 2.4e-05 24.3 0.1 7.6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EDN90809.1 - 0.0002 21.0 0.0 0.00039 20.1 0.0 1.6 2 0 0 2 2 2 1 NTPase AAA PF00004.24 EDN90809.1 - 0.00023 21.3 0.0 0.00066 19.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EDN90809.1 - 0.00059 19.7 1.1 0.0041 17.0 0.8 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 EDN90809.1 - 0.0007 19.7 0.3 0.0023 18.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDN90809.1 - 0.0022 17.8 0.4 0.009 15.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EDN90809.1 - 0.0023 17.3 0.9 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 EDN90809.1 - 0.0035 16.5 0.1 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 EDN90809.1 - 0.015 15.2 0.3 0.041 13.7 0.0 1.9 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_16 PF13191.1 EDN90809.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EDN90809.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EDN90809.1 - 0.024 14.1 0.1 0.046 13.2 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EDN90809.1 - 0.035 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EDN90809.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN90809.1 - 0.054 12.9 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EDN90809.1 - 0.058 12.9 0.2 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EDN90809.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EDN90809.1 - 0.062 12.0 0.3 0.15 10.8 0.1 1.7 1 1 1 2 2 2 0 ArgK protein IstB_IS21 PF01695.12 EDN90809.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein dNK PF01712.14 EDN90809.1 - 0.08 12.8 0.6 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase SRP54 PF00448.17 EDN90809.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AMPKBI PF04739.10 EDN90810.1 - 3.3e-30 103.9 0.8 3.3e-30 103.9 0.6 2.4 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 EDN90811.1 - 1.2e-83 280.7 0.0 1.4e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Rubis-subs-bind PF09273.6 EDN90812.1 - 7.1e-28 97.0 0.7 1.4e-27 96.0 0.5 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EDN90812.1 - 2.8e-17 63.4 0.0 4.9e-16 59.4 0.0 2.6 2 1 0 2 2 2 1 SET domain EPL1 PF10513.4 EDN90813.1 - 3.3e-30 105.4 6.5 3.3e-30 105.4 4.5 2.8 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF2390 PF09523.5 EDN90813.1 - 0.89 9.7 6.7 3.3 7.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) EF-hand_1 PF00036.27 EDN90814.1 - 2.8e-26 88.7 12.2 8.8e-07 27.7 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDN90814.1 - 9.8e-24 83.2 3.1 1.3e-12 47.6 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDN90814.1 - 2.1e-20 70.6 5.0 4.7e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDN90814.1 - 7.6e-19 66.1 11.9 2.4e-06 26.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EDN90814.1 - 3.3e-15 55.4 12.9 2.1e-05 24.0 0.7 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EDN90814.1 - 7.6e-07 29.1 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EDN90814.1 - 3.6e-06 26.6 8.4 0.0027 17.4 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EDN90814.1 - 0.093 12.6 0.1 1.9 8.4 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EDN90819.1 - 1.5e-35 122.0 0.1 1.7e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EDN90820.1 - 1.8e-44 149.7 0.1 3.3e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EDN90820.1 - 1.4e-12 47.4 0.0 1.4e-12 47.4 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN90820.1 - 3.3e-12 46.3 0.0 1.7e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN90820.1 - 4.6e-09 36.3 0.2 1.1e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN90820.1 - 3.3e-08 33.2 0.0 8.1e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN90820.1 - 6.1e-05 23.4 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDN90820.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EDN90821.1 - 1.4e-22 80.0 0.0 1.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EDN90822.1 - 4.9e-52 176.1 26.1 4.9e-52 176.1 18.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF947) IATP PF04568.7 EDN90824.1 - 0.026 14.5 6.4 0.048 13.6 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PepSY_TM_2 PF13703.1 EDN90824.1 - 0.057 13.5 0.2 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix RCR PF12273.3 EDN90824.1 - 2.5 8.6 12.2 1.7e+02 2.7 8.5 2.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mid2 PF04478.7 EDN90826.1 - 0.003 16.9 1.0 0.0071 15.7 0.7 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EDN90826.1 - 0.082 12.2 0.3 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 EDN90826.1 - 0.15 11.6 2.4 0.19 11.3 0.5 2.0 2 0 0 2 2 2 0 Podoplanin ApbA_C PF08546.6 EDN90827.1 - 1.6e-13 50.7 0.0 3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDN90827.1 - 0.017 14.6 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA VPS9 PF02204.13 EDN90831.1 - 7.2e-25 87.0 0.0 1.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EDN90833.1 - 8.4e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDN90833.1 - 0.036 13.8 0.1 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Paf1 PF03985.8 EDN90834.1 - 1.2e-52 179.1 0.0 1.7e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.8 EDN90836.1 - 2e-66 222.9 3.0 2.4e-66 222.6 2.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.1 EDN90836.1 - 0.63 9.4 6.3 0.33 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ECH PF00378.15 EDN90837.1 - 9.9e-67 224.6 0.0 1.1e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pec_lyase_C PF00544.14 EDN90838.1 - 1.5e-43 148.6 6.0 2.2e-43 148.1 4.2 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EDN90838.1 - 0.043 13.5 16.6 0.031 14.0 7.8 2.7 2 1 1 3 3 3 0 Right handed beta helix region Lipase_GDSL_2 PF13472.1 EDN90840.1 - 2.1e-12 47.5 0.0 3.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN90840.1 - 5e-05 23.2 0.2 0.001 18.9 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PBP PF01161.15 EDN90841.1 - 3.8e-16 59.2 0.1 4.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Citrate_synt PF00285.16 EDN90842.1 - 1e-77 261.2 0.2 6.1e-63 212.7 0.2 2.0 1 1 1 2 2 2 2 Citrate synthase MmgE_PrpD PF03972.9 EDN90843.1 - 1.3e-103 346.6 1.4 1.4e-103 346.4 0.9 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_18 PF12847.2 EDN90844.1 - 0.005 17.3 0.0 0.0086 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN90844.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDN90844.1 - 0.032 14.7 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EDN90844.1 - 0.065 13.6 0.0 0.2 12.0 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 EDN90845.1 - 1.7e-15 56.6 29.3 7.2e-14 51.2 7.7 2.8 2 2 1 3 3 3 2 Major Facilitator Superfamily Bax1-I PF01027.15 EDN90845.1 - 0.00097 18.7 10.4 0.00097 18.7 7.2 2.1 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sugar_tr PF00083.19 EDN90845.1 - 0.0018 16.9 1.0 0.0018 16.9 0.7 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF418 PF04235.7 EDN90845.1 - 2.7 7.6 13.3 0.79 9.3 5.9 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF418) Alpha-amylase PF00128.19 EDN90849.1 - 7.2e-67 226.0 0.1 9.2e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN90849.1 - 1e-15 57.5 0.0 2.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RNA_pol_I_A49 PF06870.7 EDN90852.1 - 8.1e-73 245.2 0.6 1e-72 244.8 0.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_L41 PF05162.8 EDN90854.1 - 1.1e-06 28.2 26.4 1.8e-06 27.4 18.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 MRP-S27 PF10037.4 EDN90854.1 - 0.1 11.5 1.1 0.17 10.8 0.8 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Pkinase PF00069.20 EDN90855.1 - 2.2e-58 197.4 0.0 3.7e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN90855.1 - 6.7e-32 110.5 0.0 5.9e-31 107.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN90855.1 - 1.5e-06 27.4 0.0 2.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN90855.1 - 0.0031 16.5 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sox_N PF12444.3 EDN90855.1 - 0.2 12.7 2.6 0.62 11.2 1.8 2.0 1 1 0 1 1 1 0 Sox developmental protein N terminal Mito_carr PF00153.22 EDN90856.1 - 5.2e-65 215.2 4.1 2.5e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF566 PF04484.7 EDN90858.1 - 0.34 10.3 16.9 0.38 10.2 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SASRP1 PF15160.1 EDN90858.1 - 4.8 6.3 10.0 6.6 5.8 7.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 TPR_2 PF07719.12 EDN90859.1 - 3.2e-08 32.8 0.6 0.76 9.8 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN90859.1 - 1.5e-06 27.5 0.0 1.3 8.7 0.0 6.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN90859.1 - 3.1e-06 27.3 4.5 0.64 10.8 0.1 7.9 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN90859.1 - 5.1e-06 26.0 0.3 8.5 6.1 0.1 5.6 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.1 EDN90859.1 - 1.1e-05 25.2 0.5 27 4.7 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDN90859.1 - 1.5e-05 24.7 0.1 0.043 14.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN90859.1 - 2.4e-05 24.8 5.6 4.2 8.1 1.8 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN90859.1 - 0.0002 20.9 0.6 0.047 13.4 0.0 4.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN90859.1 - 0.00058 20.1 1.5 0.088 13.3 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN90859.1 - 0.0011 19.2 0.6 0.4 11.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat RIX1 PF08167.7 EDN90860.1 - 1.8e-52 177.3 0.8 4e-52 176.2 0.5 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis DUF3988 PF13149.1 EDN90863.1 - 2.1 7.8 10.8 1.7 8.0 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3988) Polysacc_deac_1 PF01522.16 EDN90865.1 - 3.8e-26 91.1 0.0 6.5e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EDN90865.1 - 3.6e-15 55.6 100.6 3.3e-07 30.1 14.8 5.5 5 0 0 5 5 5 4 Chitin recognition protein CH PF00307.26 EDN90866.1 - 1e-37 128.4 0.3 1e-18 67.3 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EDN90866.1 - 5.6e-12 45.1 0.1 6.9e-08 32.0 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 EDN90866.1 - 1.8e-07 30.9 0.7 1.4e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.1 EDN90866.1 - 1e-05 25.0 0.3 0.0053 16.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EDN90866.1 - 4.7e-05 22.9 1.3 0.062 12.9 0.2 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDN90866.1 - 0.00011 21.2 0.2 0.14 11.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDN90866.1 - 0.0015 18.6 1.3 0.0054 16.8 0.9 2.0 1 0 0 1 1 1 1 EF-hand domain pair IBR PF01485.16 EDN90867.1 - 8.1e-11 41.6 48.3 4e-06 26.6 12.4 3.7 2 2 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EDN90867.1 - 0.0009 19.0 8.2 0.0009 19.0 5.7 3.2 2 1 1 3 3 3 1 Ring finger domain CAS_CSE1 PF03378.10 EDN90869.1 - 0.026 12.8 0.1 0.027 12.7 0.1 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Amidase PF01425.16 EDN90871.1 - 8.1e-37 127.1 1.3 5.7e-35 121.0 0.6 2.1 2 0 0 2 2 2 2 Amidase Phosphoesterase PF04185.9 EDN90872.1 - 2e-63 214.8 0.9 2.6e-63 214.5 0.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family UPF1_Zn_bind PF09416.5 EDN90873.1 - 0.013 15.1 0.1 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) PIR PF00399.14 EDN90874.1 - 1.8e-20 71.4 86.2 6.4e-05 22.1 3.2 8.8 8 0 0 8 8 8 7 Yeast PIR protein repeat Remorin_C PF03763.8 EDN90876.1 - 0.018 14.5 0.3 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region ADH_zinc_N PF00107.21 EDN90880.1 - 1.1e-22 80.0 0.0 1.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN90880.1 - 5.8e-15 56.3 0.0 1.1e-14 55.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN90880.1 - 5.1e-10 39.0 0.1 2.3e-09 36.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF1204 PF06721.6 EDN90880.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Bestrophin PF01062.16 EDN90881.1 - 1.5e-21 76.5 0.0 1.8e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Shal-type PF11601.3 EDN90881.1 - 0.027 13.9 1.5 0.07 12.6 1.0 1.6 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Tom22 PF04281.8 EDN90882.1 - 7.9e-49 164.7 3.4 9.7e-49 164.4 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF664 PF04978.7 EDN90882.1 - 0.043 14.0 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF664) CX PF01705.14 EDN90883.1 - 0.037 14.0 0.6 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 CX module SAP PF02037.22 EDN90883.1 - 0.11 12.0 0.1 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 SAP domain DUF572 PF04502.8 EDN90885.1 - 0.43 9.7 4.1 2.2 7.4 2.8 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF104 PF01954.11 EDN90886.1 - 0.016 15.1 1.3 0.032 14.2 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF104 UPF0180 PF03698.8 EDN90888.1 - 0.016 15.0 0.2 0.018 14.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DUF3591 PF12157.3 EDN90888.1 - 0.16 10.3 0.6 0.16 10.3 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) DUF1264 PF06884.6 EDN90889.1 - 2.2e-76 255.0 0.1 2.7e-76 254.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Lactamase_B PF00753.22 EDN90890.1 - 1.9e-26 92.8 1.5 7e-26 91.0 1.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN90890.1 - 5.3e-07 29.3 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Tctex-1 PF03645.8 EDN90890.1 - 0.0083 15.9 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Tctex-1 family Ras_bdg_2 PF14847.1 EDN90890.1 - 0.045 13.6 0.4 3.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Ras-binding domain of Byr2 BcrAD_BadFG PF01869.15 EDN90890.1 - 0.065 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF2855 PF11017.3 EDN90890.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF2649 PF10854.3 EDN90890.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) NAD_binding_5 PF07994.7 EDN90890.1 - 0.12 11.8 1.3 3.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase DUF4449 PF14613.1 EDN90891.1 - 4.9e-61 205.4 6.4 1.4e-60 203.9 4.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF993 PF06187.6 EDN90891.1 - 0.058 11.9 1.2 1.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF993) DUF4211 PF13926.1 EDN90892.1 - 1.1e-36 125.5 0.3 3.3e-36 123.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) EF-hand_9 PF14658.1 EDN90896.1 - 1.8e-05 24.5 0.0 0.0051 16.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain IF4E PF01652.13 EDN90897.1 - 9.9e-37 126.0 0.0 1.2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EDN90898.1 - 3.1e-14 53.2 4.0 3.1e-14 53.2 2.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Kinesin PF00225.18 EDN90899.1 - 1.6e-112 375.5 0.0 2.5e-112 374.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain RTC PF01137.16 EDN90899.1 - 0.017 13.8 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase AAA_33 PF13671.1 EDN90899.1 - 0.03 14.1 0.1 9.8 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDN90899.1 - 0.62 9.8 0.0 0.62 9.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AMP-binding PF00501.23 EDN90900.1 - 0.0011 17.4 0.0 0.0011 17.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ARD PF03079.9 EDN90901.1 - 4.1e-27 95.0 4.4 1.4e-24 86.7 3.1 2.0 1 1 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EDN90901.1 - 2.8e-05 23.5 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 EDN90902.1 - 3.2e-22 79.2 0.0 5.3e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN90902.1 - 2.3e-11 43.7 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN90902.1 - 7.8e-07 28.7 0.1 1.5e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN90902.1 - 1.9e-06 27.0 0.0 2.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EDN90902.1 - 4.5e-06 26.6 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 EDN90902.1 - 6.5e-05 21.9 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDN90902.1 - 0.00034 20.6 0.0 0.00057 19.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDN90902.1 - 0.0014 17.6 0.1 0.014 14.3 0.0 2.4 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EDN90902.1 - 0.0019 17.4 0.0 0.0096 15.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_2 PF03446.10 EDN90902.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 EDN90902.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EDN90902.1 - 0.036 14.4 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DER1 PF04511.10 EDN90903.1 - 1e-10 41.4 0.1 1.3e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 EDN90904.1 - 1.1e-28 99.1 0.2 1.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDN90904.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDN90904.1 - 0.0092 15.2 0.4 0.016 14.4 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EDN90904.1 - 0.025 14.6 0.1 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GHMP_kinases_N PF00288.21 EDN90905.1 - 5.8e-14 51.9 0.3 1.1e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDN90905.1 - 0.0044 17.1 0.1 0.071 13.3 0.1 2.2 1 1 1 2 2 2 1 GHMP kinases C terminal GARS_A PF01071.14 EDN90906.1 - 5.8e-84 280.5 0.2 1.5e-83 279.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EDN90906.1 - 2.9e-34 117.5 0.0 9.6e-34 115.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EDN90906.1 - 3.9e-31 108.1 0.0 9.1e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EDN90906.1 - 3.1e-26 91.3 0.2 7.6e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EDN90906.1 - 2.9e-16 59.4 0.9 1.2e-15 57.5 0.6 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EDN90906.1 - 6.5e-13 48.8 0.0 8e-12 45.2 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN90906.1 - 5.4e-07 28.6 0.0 1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDN90906.1 - 3.9e-06 26.3 0.0 1.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDN90906.1 - 3.6e-05 23.1 0.0 8.5e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EDN90906.1 - 0.00028 20.8 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EDN90906.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDN90906.1 - 0.0023 17.4 0.0 0.0077 15.7 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN90906.1 - 0.028 13.8 0.0 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus SOR_SNZ PF01680.12 EDN90907.1 - 1.2e-112 374.5 5.1 1.8e-112 373.9 3.5 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EDN90907.1 - 2.3e-09 36.7 5.7 2.8e-06 26.5 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EDN90907.1 - 0.0019 17.5 0.5 0.14 11.3 0.0 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EDN90907.1 - 0.0029 16.7 0.0 0.032 13.2 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EDN90907.1 - 0.0029 16.5 0.7 0.073 12.0 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EDN90907.1 - 0.004 16.0 3.6 0.38 9.5 0.1 2.8 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NMO PF03060.10 EDN90907.1 - 0.0082 15.3 0.4 0.0082 15.3 0.3 2.2 2 1 0 2 2 2 1 Nitronate monooxygenase RNase_P_p30 PF01876.11 EDN90908.1 - 0.027 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit p30 Xpo1 PF08389.7 EDN90909.1 - 0.00044 20.1 0.5 0.098 12.5 0.2 3.8 2 2 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 EDN90909.1 - 0.064 13.5 0.1 25 5.2 0.0 4.4 4 1 1 5 5 5 0 HEAT repeats Peptidase_M24 PF00557.19 EDN90910.1 - 1.3e-43 149.0 0.0 2.7e-43 147.9 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDN90910.1 - 4.4e-18 66.0 0.0 3.2e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sad1_UNC PF07738.8 EDN90911.1 - 3.4e-33 114.3 0.1 8.1e-33 113.0 0.0 1.8 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal MOZ_SAS PF01853.13 EDN90912.1 - 2.4e-77 258.4 0.0 3.4e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EDN90912.1 - 0.00014 21.4 8.9 0.00014 21.4 6.2 2.1 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 EDN90912.1 - 0.003 17.0 1.2 0.0061 16.0 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PHD_2 PF13831.1 EDN90912.1 - 0.63 9.4 6.2 0.12 11.7 1.7 1.8 2 0 0 2 2 2 0 PHD-finger MFS_1 PF07690.11 EDN90915.1 - 1.1e-47 162.4 30.1 4.5e-42 144.0 13.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN90915.1 - 5.8e-11 41.6 1.9 5.8e-11 41.6 1.3 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MRP-L27 PF09809.4 EDN90916.1 - 5.2e-17 61.4 0.2 5.7e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 EDN90917.1 - 6.2e-229 761.9 60.8 6.2e-229 761.9 42.1 2.1 2 0 0 2 2 2 1 Utp14 protein PP_kinase PF02503.12 EDN90917.1 - 0.43 10.0 5.6 7 6.1 0.3 2.9 3 0 0 3 3 3 0 Polyphosphate kinase middle domain Glyco_hydro_81 PF03639.8 EDN90921.1 - 1.8e-175 584.8 9.9 2e-175 584.7 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Sec16 PF12932.2 EDN90922.1 - 0.044 13.7 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Cyclin_N PF00134.18 EDN90923.1 - 7.1e-14 51.4 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDN90923.1 - 1.2e-09 38.7 0.0 2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin adh_short PF00106.20 EDN90926.1 - 0.012 15.5 0.7 0.091 12.6 0.0 2.8 4 0 0 4 4 4 0 short chain dehydrogenase Acyltransferase PF01553.16 EDN90927.1 - 3.1e-11 42.8 0.0 3.4e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.19 EDN90928.1 - 3.8e-48 162.6 35.9 6.5e-27 93.8 7.0 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Stn1 PF10451.4 EDN90929.1 - 5.7e-07 28.6 3.0 0.00012 21.0 0.1 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DUF2360 PF10152.4 EDN90929.1 - 0.13 12.5 2.7 10 6.3 0.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TMEM171 PF15471.1 EDN90929.1 - 4.3 6.0 9.5 15 4.2 6.4 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 DnaJ PF00226.26 EDN90930.1 - 3.5e-23 81.0 1.7 3.5e-23 81.0 1.2 2.4 2 0 0 2 2 2 1 DnaJ domain DDE_1 PF03184.14 EDN90931.1 - 2.9e-08 33.1 0.0 3e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Pectinesterase PF01095.14 EDN90932.1 - 2.3e-23 82.1 2.4 3.2e-17 62.0 0.7 2.1 1 1 1 2 2 2 2 Pectinesterase MFS_1 PF07690.11 EDN90933.1 - 9.1e-25 87.0 49.7 7.8e-15 54.4 16.2 3.8 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EDN90933.1 - 2e-12 46.1 15.2 3.6e-12 45.2 10.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Piwi PF02171.12 EDN90934.1 - 1.1e-69 234.7 0.0 1.6e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EDN90934.1 - 7.2e-16 57.2 0.0 1.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EDN90934.1 - 2.7e-08 33.2 0.0 8.7e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 PAZ domain Baculo_PEP_C PF04513.7 EDN90940.1 - 0.028 14.2 1.2 0.59 9.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup96 PF12110.3 EDN90941.1 - 2.8e-94 315.4 4.2 3.9e-94 315.0 2.9 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EDN90941.1 - 1e-47 161.5 0.0 2.3e-47 160.3 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EDN90941.1 - 4.8e-12 46.1 367.9 4.6e-08 33.2 25.0 10.9 3 2 5 8 8 8 5 Nucleoporin FG repeat region EF-hand_1 PF00036.27 EDN90942.1 - 8.8e-18 62.2 6.7 2e-06 26.6 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EDN90942.1 - 2.1e-17 63.0 2.3 4e-11 42.8 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDN90942.1 - 9.6e-16 56.1 4.7 3.9e-06 26.2 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EDN90942.1 - 2.3e-14 52.7 7.6 2.5e-08 33.4 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EDN90942.1 - 1.6e-05 24.0 7.1 0.0013 17.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EDN90942.1 - 0.0025 17.5 0.1 0.05 13.3 0.0 2.5 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand ENTH PF01417.15 EDN90943.1 - 6.6e-48 161.6 0.1 1.1e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EDN90943.1 - 6.2e-07 29.3 24.1 6.2e-07 29.3 16.7 4.4 2 2 1 3 3 3 1 Domain of unknown function (DUF1720) ANTH PF07651.11 EDN90943.1 - 0.0031 16.2 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EDN90943.1 - 0.028 13.7 0.1 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 EDN90943.1 - 0.041 13.4 0.8 0.041 13.4 0.6 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 EDN90943.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF1556 PF07590.6 EDN90943.1 - 0.8 9.9 4.5 4.5 7.5 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) MMR_HSR1 PF01926.18 EDN90944.1 - 1.2e-20 73.5 0.0 2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN90944.1 - 1.4e-05 24.5 0.0 0.00011 21.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN90944.1 - 0.00067 18.8 0.1 0.0012 18.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN90944.1 - 0.00069 19.4 0.0 0.033 14.0 0.0 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EDN90944.1 - 0.00093 18.4 0.0 0.002 17.4 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EDN90944.1 - 0.0029 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 EDN90944.1 - 0.0049 15.9 0.0 0.013 14.5 0.0 1.6 1 1 1 2 2 2 1 Septin Miro PF08477.8 EDN90944.1 - 0.0061 17.0 0.0 0.013 16.0 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EDN90944.1 - 0.0095 15.6 0.2 0.087 12.5 0.0 2.0 1 1 0 2 2 2 1 Archaeal ATPase AIG1 PF04548.11 EDN90944.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family ATP_bind_1 PF03029.12 EDN90944.1 - 0.013 15.1 0.0 0.028 13.9 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EDN90944.1 - 0.029 14.5 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN90944.1 - 0.046 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EDN90944.1 - 0.085 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EDN90944.1 - 0.11 12.4 0.1 0.41 10.6 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Complex1_LYR_2 PF13233.1 EDN90945.1 - 5.5e-19 68.5 0.3 6.6e-19 68.3 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN90945.1 - 0.067 13.0 1.2 0.1 12.3 0.8 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) MFS_1 PF07690.11 EDN90949.1 - 4.7e-16 58.4 32.5 1.6e-13 50.1 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EDN90949.1 - 1.2e-05 24.2 9.3 1.2e-05 24.2 6.4 1.4 1 1 0 1 1 1 1 Nucleoside H+ symporter MFS_2 PF13347.1 EDN90949.1 - 0.011 14.1 16.0 0.012 14.0 9.1 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein Sec3_C PF09763.4 EDN90950.1 - 1e-244 813.9 0.0 1.3e-244 813.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EDN90950.1 - 3e-31 107.1 0.0 7e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EDN90950.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.7 EDN90950.1 - 0.077 11.5 2.1 0.048 12.1 0.2 1.5 2 0 0 2 2 2 0 Vps52 / Sac2 family SRP40_C PF05022.7 EDN90951.1 - 1.5e-25 89.4 0.9 3.8e-25 88.1 0.6 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain A_deaminase PF00962.17 EDN90952.1 - 7.3e-42 143.4 0.0 7e-41 140.2 0.0 2.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase TMEM171 PF15471.1 EDN90954.1 - 0.087 11.5 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 NMO PF03060.10 EDN90955.1 - 9e-65 218.9 0.2 1.4e-64 218.3 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDN90955.1 - 1.3e-10 40.7 0.0 0.00024 20.0 0.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDN90955.1 - 0.0029 16.4 0.2 0.0049 15.7 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EDN90955.1 - 0.0063 15.8 0.0 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EDN90955.1 - 0.032 13.1 0.1 0.12 11.2 0.2 2.0 2 1 0 2 2 2 0 Conserved region in glutamate synthase DUF1902 PF08972.6 EDN90955.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF4263 PF14082.1 EDN90956.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DND1_DSRM PF14709.1 EDN90957.1 - 0.031 14.5 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.16 EDN90958.1 - 5.5e-29 100.6 0.0 8.8e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.21 EDN90960.1 - 2e-19 70.1 0.9 2.3e-13 50.5 0.0 2.8 3 0 0 3 3 3 2 Universal stress protein family Lipocalin_4 PF13648.1 EDN90962.1 - 0.012 16.2 0.4 0.017 15.6 0.2 1.3 1 0 0 1 1 1 0 Lipocalin-like domain NOA36 PF06524.7 EDN90962.1 - 4 6.6 7.5 5.4 6.1 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.17 EDN90963.1 - 1.9e-81 267.6 3.8 1.4e-22 79.0 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN90963.1 - 2.2e-52 174.8 0.3 9.7e-16 57.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN90963.1 - 2e-36 123.6 0.1 3.5e-08 33.1 0.0 5.6 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EDN90963.1 - 2.8e-30 103.7 1.4 1.1e-29 101.9 0.9 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EDN90963.1 - 0.00041 20.0 0.9 0.48 10.2 0.0 3.5 2 1 1 3 3 3 1 Limkain b1 CbiG_mid PF11761.3 EDN90963.1 - 0.0012 19.0 0.1 3.9 7.7 0.0 3.8 3 0 0 3 3 3 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EDN90963.1 - 0.0025 17.5 1.5 24 4.7 0.1 4.5 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif YflT PF11181.3 EDN90963.1 - 0.0065 16.6 4.9 2.7 8.1 0.2 3.4 3 0 0 3 3 3 2 Heat induced stress protein YflT OB_RNB PF08206.6 EDN90963.1 - 0.42 10.1 3.2 20 4.8 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DDE_1 PF03184.14 EDN90964.1 - 3.2e-49 167.0 0.0 5.4e-48 162.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN90964.1 - 1.7e-12 47.2 0.0 3.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN90964.1 - 2e-11 43.5 0.2 7.3e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN90964.1 - 0.0089 16.1 0.1 0.043 13.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HECT PF00632.20 EDN90965.1 - 1.3e-84 284.1 0.0 2.4e-84 283.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EDN90965.1 - 0.0012 18.2 0.0 0.0053 16.2 0.0 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Aldo_ket_red PF00248.16 EDN90966.1 - 1.3e-23 83.2 0.0 1.5e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.11 EDN90967.1 - 3.6e-48 164.4 0.1 4.5e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Neisseria_TspB PF05616.8 EDN90971.1 - 0.029 12.7 0.2 0.033 12.5 0.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2946 PF11162.3 EDN90971.1 - 0.52 10.5 6.6 0.78 9.9 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Ala_racemase_N PF01168.15 EDN90972.1 - 1.6e-42 145.5 0.0 2e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MS_channel PF00924.13 EDN90973.1 - 2.9e-18 65.9 2.5 6.1e-18 64.8 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EDN90973.1 - 0.00085 18.4 0.6 0.0025 16.9 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EDN90973.1 - 0.011 15.5 0.1 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EDN90973.1 - 0.024 14.7 0.3 0.074 13.2 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EDN90973.1 - 0.44 9.9 4.2 0.11 11.8 0.2 2.0 2 0 0 2 2 2 0 EF hand COesterase PF00135.23 EDN90976.1 - 2.5e-98 330.1 1.2 1.1e-88 298.3 0.3 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN90976.1 - 5.5e-11 42.4 0.0 9.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN90976.1 - 0.033 13.9 0.1 0.25 11.0 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DNA_methylase PF00145.12 EDN90977.1 - 2.2e-29 102.6 0.0 1.1e-22 80.5 0.0 2.2 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase SRP19 PF01922.12 EDN90978.1 - 5.9e-30 103.7 0.0 1.2e-29 102.7 0.0 1.5 2 0 0 2 2 2 1 SRP19 protein CactinC_cactus PF09732.4 EDN90979.1 - 0.017 14.7 0.2 0.051 13.1 0.2 1.6 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein Hexapep PF00132.19 EDN90982.1 - 2e-08 33.3 1.5 0.0072 15.7 0.2 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDN90982.1 - 0.0026 17.8 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EDN90982.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Toxin_21 PF08091.6 EDN90983.1 - 1.4 8.6 9.7 7.6 6.3 0.5 2.7 2 0 0 2 2 2 0 Spider insecticidal peptide zf-Di19 PF05605.7 EDN90987.1 - 0.73 10.0 3.7 2 8.6 2.6 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FMN_bind_2 PF04299.7 EDN90988.1 - 1.1e-40 138.8 0.0 1.6e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain zf-C2H2 PF00096.21 EDN90989.1 - 1.4e-07 31.3 7.4 0.004 17.4 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN90989.1 - 3.5e-07 30.0 11.5 0.0014 18.7 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN90989.1 - 0.0034 17.6 7.6 0.02 15.1 1.7 2.6 2 0 0 2 2 2 1 Zinc-finger double domain IBR PF01485.16 EDN90989.1 - 0.022 14.6 0.3 0.049 13.5 0.2 1.5 1 0 0 1 1 1 0 IBR domain zf-TRAF PF02176.13 EDN90989.1 - 0.066 13.6 1.6 0.16 12.4 1.1 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 EDN90989.1 - 0.11 12.6 4.4 0.17 12.0 0.1 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EDN90989.1 - 4.9 6.9 8.1 0.25 11.0 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type F-box-like PF12937.2 EDN90991.1 - 0.00051 19.7 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EDN90991.1 - 0.028 14.3 6.2 2.8 8.3 0.0 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.1 EDN90991.1 - 0.051 13.3 0.0 0.051 13.3 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EDN90991.1 - 0.52 10.5 0.0 0.52 10.5 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat Fungal_trans_2 PF11951.3 EDN90992.1 - 1.1e-45 155.9 0.0 1.5e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN90992.1 - 0.0015 18.3 6.1 0.003 17.4 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NARP1 PF12569.3 EDN90994.1 - 1 8.0 5.5 1.7 7.2 3.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FSH1 PF03959.8 EDN90996.1 - 2.2e-25 89.3 0.0 5.5e-25 88.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Glycophorin_A PF01102.13 EDN90997.1 - 0.04 13.6 7.3 0.067 12.9 4.5 1.9 1 1 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.1 EDN90997.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fungal_trans PF04082.13 EDN90998.1 - 1.4e-34 119.1 0.5 2.7e-34 118.2 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN90998.1 - 8.4e-06 25.6 8.2 1.7e-05 24.5 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EDN91001.1 - 8.5e-26 89.8 5.5 1.5e-25 89.0 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN91001.1 - 2.1e-18 66.1 0.0 7.1e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN91001.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EDN91001.1 - 0.077 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1508 PF07411.7 EDN91001.1 - 0.5 9.8 1.8 22 4.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) F-box-like PF12937.2 EDN91002.1 - 1.1e-06 28.2 0.8 2.4e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN91002.1 - 0.00056 19.4 0.3 0.0013 18.3 0.2 1.7 1 0 0 1 1 1 1 F-box domain CENP-S PF15630.1 EDN91003.1 - 1.2e-34 118.3 0.1 1.7e-34 117.8 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EDN91003.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EDN91003.1 - 0.0017 18.0 0.0 0.0047 16.6 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.11 EDN91003.1 - 0.0065 16.2 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T PF15511.1 EDN91003.1 - 0.0066 15.7 0.0 0.0088 15.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TAF PF02969.12 EDN91003.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) YhfZ_C PF14503.1 EDN91003.1 - 0.094 12.0 0.1 0.098 11.9 0.1 1.1 1 0 0 1 1 1 0 YhfZ C-terminal domain TFIID-31kDa PF02291.10 EDN91003.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PGA2 PF07543.7 EDN91004.1 - 1.7e-42 144.5 8.5 2e-42 144.3 5.9 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 Synaptobrevin PF00957.16 EDN91004.1 - 0.9 9.1 3.8 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Synaptobrevin ZZ PF00569.12 EDN91005.1 - 0.0053 16.2 7.4 0.045 13.3 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, ZZ type DUF3133 PF11331.3 EDN91005.1 - 3.9 7.1 5.4 10 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) p450 PF00067.17 EDN91006.1 - 3.6e-17 62.0 0.0 1.1e-15 57.1 0.0 2.6 1 1 1 2 2 2 1 Cytochrome P450 PB1 PF00564.19 EDN91007.1 - 0.015 14.9 0.1 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 PB1 domain Zn_clus PF00172.13 EDN91008.1 - 0.0028 17.5 2.1 0.0028 17.5 1.5 2.5 2 1 1 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DCR PF14047.1 EDN91012.1 - 0.25 11.6 1.2 0.27 11.5 0.1 1.8 2 1 0 2 2 2 0 Dppa2/4 conserved region Peptidase_M50B PF13398.1 EDN91013.1 - 0.017 14.4 0.4 0.021 14.1 0.3 1.1 1 0 0 1 1 1 0 Peptidase M50B-like DUF4131 PF13567.1 EDN91013.1 - 0.29 10.5 1.9 0.35 10.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WAC_Acf1_DNA_bd PF10537.4 EDN91015.1 - 0.0037 17.4 0.1 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal HeLo PF14479.1 EDN91015.1 - 0.08 12.6 1.1 0.4 10.3 0.6 2.2 1 1 0 1 1 1 0 Prion-inhibition and propagation zf-Di19 PF05605.7 EDN91015.1 - 2 8.5 12.2 0.6 10.2 0.6 4.1 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding ETX_MTX2 PF03318.8 EDN91017.1 - 2.5e-06 27.1 19.8 4.9e-06 26.2 13.7 1.5 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Crystall PF00030.14 EDN91017.1 - 0.00029 20.6 0.1 0.66 9.8 0.0 3.0 2 1 0 2 2 2 2 Beta/Gamma crystallin MFS_1 PF07690.11 EDN91022.1 - 1.2e-13 50.4 53.5 6.9e-10 38.1 4.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Metallophos PF00149.23 EDN91023.1 - 2.9e-09 36.6 0.7 6.6e-09 35.4 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN91023.1 - 5.4e-05 23.0 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Vg_Tdu PF07545.9 EDN91023.1 - 0.072 12.5 0.4 0.16 11.4 0.3 1.6 1 0 0 1 1 1 0 Vestigial/Tondu family NAD_binding_8 PF13450.1 EDN91024.1 - 8.8e-11 41.6 0.1 9.9e-10 38.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN91024.1 - 7.3e-10 39.0 0.1 3.2e-06 27.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN91024.1 - 7.6e-07 28.3 1.3 3.3e-05 22.9 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN91024.1 - 7.8e-07 29.4 0.1 0.01 16.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN91024.1 - 8.1e-07 28.2 0.5 5.1e-06 25.5 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EDN91024.1 - 8.6e-06 24.4 0.6 0.00031 19.3 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EDN91024.1 - 0.00012 21.2 0.1 0.00025 20.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EDN91024.1 - 0.00019 20.6 0.1 0.00075 18.6 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN91024.1 - 0.00041 20.4 0.1 0.0015 18.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN91024.1 - 0.0012 18.5 0.0 0.0096 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDN91024.1 - 0.0019 17.1 0.2 0.0031 16.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Malic_M PF03949.10 EDN91024.1 - 0.0045 16.5 0.5 0.033 13.7 0.1 2.0 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain Trp_halogenase PF04820.9 EDN91024.1 - 0.034 12.7 0.6 0.068 11.7 0.4 1.5 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 EDN91024.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EDN91024.1 - 0.089 11.6 0.2 0.14 10.9 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EDN91024.1 - 0.11 11.5 0.1 0.29 10.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Sec1 PF00995.18 EDN91025.1 - 8.2e-113 377.9 0.0 1e-112 377.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MBOAT PF03062.14 EDN91026.1 - 1.3e-50 172.3 6.1 1.3e-50 172.3 4.2 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.6 EDN91026.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Synaptobrevin PF00957.16 EDN91027.1 - 0.26 10.9 0.7 0.59 9.7 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin Abi PF02517.11 EDN91028.1 - 2.5e-15 56.3 11.3 9.7e-15 54.4 5.0 2.3 1 1 1 2 2 2 2 CAAX protease self-immunity Thioredoxin PF00085.15 EDN91029.1 - 4.3e-05 23.1 0.0 8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Mt_ATP-synt_B PF05405.9 EDN91029.1 - 0.035 13.5 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) UAA PF08449.6 EDN91030.1 - 1.5e-12 47.1 21.0 1.9e-12 46.7 14.5 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDN91030.1 - 9.7e-09 35.0 9.6 9.7e-09 35.0 6.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDN91030.1 - 2e-05 24.6 31.2 0.00052 20.0 6.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2404 PF10296.4 EDN91031.1 - 3.6e-08 33.4 0.0 9.7e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Gly_transf_sug PF04488.10 EDN91032.1 - 8.6e-20 71.0 0.0 2.1e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EDN91032.1 - 0.0013 17.3 5.8 0.17 10.3 0.3 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DNA_pol3_delta2 PF13177.1 EDN91033.1 - 1e-11 44.7 0.0 8.4e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDN91033.1 - 2.3e-11 44.0 0.0 5.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDN91033.1 - 4.3e-07 29.8 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN91033.1 - 1.4e-06 28.4 0.1 7.7e-05 22.7 0.0 2.6 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EDN91033.1 - 1.4e-05 24.2 0.0 3.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EDN91033.1 - 1.5e-05 23.9 0.0 0.011 14.4 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDN91033.1 - 1.8e-05 24.9 0.1 0.0046 17.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDN91033.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EDN91033.1 - 0.00017 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDN91033.1 - 0.00018 21.0 0.1 0.042 13.2 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EDN91033.1 - 0.001 18.5 0.1 0.07 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN91033.1 - 0.0017 18.0 0.0 0.0044 16.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EDN91033.1 - 0.0025 17.0 0.0 0.023 13.8 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EDN91033.1 - 0.0033 16.9 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.24 EDN91033.1 - 0.0037 16.7 0.1 0.16 11.4 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 EDN91033.1 - 0.0055 16.4 0.1 0.028 14.1 0.1 2.0 1 1 0 2 2 2 1 NTPase ArgK PF03308.11 EDN91033.1 - 0.0059 15.4 0.1 0.016 13.9 0.0 1.6 1 1 1 2 2 2 1 ArgK protein AAA_5 PF07728.9 EDN91033.1 - 0.0092 15.7 0.1 0.041 13.6 0.0 2.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) KTI12 PF08433.5 EDN91033.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 EDN91033.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN91033.1 - 0.014 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN91033.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EDN91033.1 - 0.017 15.0 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN91033.1 - 0.058 13.5 0.0 0.63 10.2 0.0 2.6 2 1 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EDN91033.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.6 EDN91033.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_30 PF13604.1 EDN91033.1 - 0.12 11.9 0.2 2 7.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain IGPD PF00475.13 EDN91035.1 - 4.7e-61 204.9 0.2 6e-61 204.5 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase CENP-H PF05837.7 EDN91036.1 - 1.5 9.0 11.7 0.54 10.4 2.9 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Abhydrolase_6 PF12697.2 EDN91037.1 - 4.8e-08 33.1 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN91037.1 - 6.8e-07 29.0 0.0 1.8e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 EDN91037.1 - 0.14 11.8 0.0 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Cutinase Cohesin_load PF10345.4 EDN91038.1 - 5e-188 626.1 8.8 5.8e-188 625.9 6.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 EDN91038.1 - 0.13 12.2 13.1 0.92 9.4 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN91038.1 - 9.4 6.4 14.5 4.6 7.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Pet127 PF08634.5 EDN91039.1 - 4.5e-117 390.0 4.7 6e-117 389.6 1.8 2.1 2 0 0 2 2 2 1 Mitochondrial protein Pet127 7tm_2 PF00002.19 EDN91041.1 - 0.05 12.6 0.8 2 7.4 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) RRM_1 PF00076.17 EDN91042.1 - 3e-41 138.8 0.4 2.3e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN91042.1 - 4.7e-34 116.1 0.1 1.1e-18 66.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EDN91042.1 - 2.2e-29 101.5 0.3 5.5e-29 100.2 0.2 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EDN91042.1 - 4.3e-22 77.7 0.0 2.9e-09 36.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN91042.1 - 0.012 15.4 0.0 0.077 12.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.23 EDN91043.1 - 4.1e-18 64.9 0.2 3e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EDN91043.1 - 2.3e-08 34.4 23.2 9.2e-08 32.4 15.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EDN91043.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Het-C PF07217.6 EDN91044.1 - 1e-292 971.8 0.0 1.3e-292 971.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CDC45 PF02724.9 EDN91045.1 - 0.5 8.3 4.7 0.45 8.4 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EDN91045.1 - 1.1 8.2 10.5 0.97 8.4 7.3 1.1 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.7 EDN91045.1 - 1.3 7.6 8.0 1.4 7.5 5.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Pox_Ag35 PF03286.9 EDN91045.1 - 3.8 6.9 8.5 5.5 6.4 5.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UL2 PF08196.6 EDN91047.1 - 0.059 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 UL2 protein CK_II_beta PF01214.13 EDN91047.1 - 0.15 11.5 0.7 0.16 11.4 0.5 1.1 1 0 0 1 1 1 0 Casein kinase II regulatory subunit FGGY_C PF02782.11 EDN91049.1 - 5.1e-74 248.1 0.6 7.4e-74 247.6 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDN91049.1 - 6.7e-65 218.8 0.0 9.1e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CPSF73-100_C PF11718.3 EDN91050.1 - 1.5e-76 256.5 0.0 1.2e-73 247.0 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EDN91050.1 - 2.8e-32 111.2 0.0 1.6e-31 108.8 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EDN91050.1 - 7.8e-15 55.0 2.8 1.7e-14 53.9 1.9 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN91050.1 - 5.3e-11 42.4 0.9 1e-10 41.5 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EDN91050.1 - 1.5e-07 31.0 0.2 3.8e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EDN91050.1 - 2e-06 27.6 0.1 4.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EDN91051.1 - 1e-19 70.8 0.0 2.5e-17 63.0 0.0 2.9 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Nramp PF01566.13 EDN91052.1 - 4e-88 295.6 15.0 6.6e-88 294.8 10.4 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Cellulase PF00150.13 EDN91056.1 - 1.9e-47 161.8 0.0 2.4e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1987 PF09345.5 EDN91059.1 - 0.014 15.1 0.1 0.07 12.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1987) Thiolase_N PF00108.18 EDN91062.1 - 1.3e-76 257.1 0.8 2.4e-76 256.2 0.6 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN91062.1 - 2.1e-44 149.8 0.2 5e-44 148.6 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN91062.1 - 0.017 14.6 1.1 0.08 12.3 0.4 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EDN91062.1 - 0.04 13.9 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LMWSLP_N PF12211.3 EDN91062.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal DUF3481 PF11980.3 EDN91065.1 - 0.19 11.5 0.4 0.26 11.1 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) Pectinesterase PF01095.14 EDN91066.1 - 1.3e-43 148.7 2.9 1.7e-43 148.3 2.0 1.1 1 0 0 1 1 1 1 Pectinesterase Flp_N PF03930.9 EDN91068.1 - 0.039 13.7 0.2 0.26 11.0 0.1 2.4 2 1 0 2 2 2 0 Recombinase Flp protein N-terminus Glyco_hydro_17 PF00332.13 EDN91069.1 - 8e-11 41.5 2.8 1.2e-06 27.8 0.8 2.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Isochorismatase PF00857.15 EDN91070.1 - 1.5e-41 142.1 0.1 1.8e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF3166 PF11365.3 EDN91070.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) SRR1 PF07985.7 EDN91071.1 - 4.4e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 SRR1 DDE_1 PF03184.14 EDN91073.1 - 2.2e-38 131.5 0.2 5e-38 130.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91073.1 - 1.3e-14 53.6 0.1 9.7e-14 50.9 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN91073.1 - 8.3e-06 25.6 0.0 2.1e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF3373 PF11853.3 EDN91074.1 - 0.16 10.4 0.4 0.15 10.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PFU PF09070.6 EDN91075.1 - 2.8e-43 146.6 0.2 5.7e-43 145.6 0.2 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EDN91075.1 - 6.8e-43 146.3 0.0 9.4e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EDN91075.1 - 9.7e-40 133.0 15.3 2.8e-08 33.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PC4 PF02229.11 EDN91075.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) WD40 PF00400.27 EDN91076.1 - 8.4e-41 136.4 9.3 1.2e-11 43.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN91076.1 - 0.0027 16.5 0.0 0.1 11.3 0.0 2.2 2 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EDN91076.1 - 0.0069 14.5 0.3 1.5 6.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Drf_GBD PF06371.8 EDN91077.1 - 2.7e-15 56.2 3.7 7.1e-14 51.5 2.5 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Suc_Fer-like PF06999.7 EDN91078.1 - 2.1e-35 122.7 0.0 3e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pribosyltran PF00156.22 EDN91081.1 - 1.2e-21 76.7 0.0 1.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain But2 PF09792.4 EDN91082.1 - 3.6e-47 159.7 3.3 3.6e-47 159.7 2.3 3.1 2 1 2 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain FAD_binding_4 PF01565.18 EDN91083.1 - 2.5e-08 33.4 4.4 7.7e-08 31.9 3.1 2.0 1 1 0 1 1 1 1 FAD binding domain IBR PF01485.16 EDN91086.1 - 9.5e-10 38.2 2.5 9.5e-10 38.2 1.8 4.3 3 2 0 3 3 3 2 IBR domain Myosin_head PF00063.16 EDN91087.1 - 4.2e-246 818.3 0.0 4.2e-246 818.3 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EDN91087.1 - 8.4e-27 93.3 277.0 3.8e-14 51.4 27.7 6.1 3 2 3 6 6 6 5 Myosin tail Myosin_N PF02736.14 EDN91087.1 - 1.8e-05 24.3 0.1 5.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EDN91087.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain V-SNARE_C PF12352.3 EDN91088.1 - 0.0078 16.2 2.2 0.024 14.7 1.5 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus MFS_1 PF07690.11 EDN91089.1 - 4.2e-33 114.5 36.6 4.2e-33 114.5 25.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RNA12 PF10443.4 EDN91091.1 - 3.6e-170 566.1 2.2 4.7e-170 565.7 0.5 1.7 2 0 0 2 2 2 1 RNA12 protein Arch_ATPase PF01637.13 EDN91091.1 - 1.6e-05 24.7 0.0 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase RRM_1 PF00076.17 EDN91091.1 - 0.00021 20.8 0.1 0.00062 19.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EDN91091.1 - 0.028 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Sp100 PF03172.8 EDN91091.1 - 0.029 14.3 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Sp100 domain RRM_5 PF13893.1 EDN91091.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRK PF07533.11 EDN91091.1 - 0.11 12.0 0.3 21 4.6 0.1 2.7 2 0 0 2 2 2 0 BRK domain DBD_Tnp_Hermes PF10683.4 EDN91091.1 - 0.11 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF3128 PF11326.3 EDN91092.1 - 1.9e-31 107.9 2.6 3.9e-31 106.9 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Spt20 PF12090.3 EDN91093.1 - 7e-06 25.5 0.0 7e-06 25.5 0.0 4.3 3 1 0 3 3 3 1 Spt20 family RVT_1 PF00078.22 EDN91095.1 - 3e-21 75.7 0.1 5.9e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_IV PF05190.13 EDN91097.1 - 0.075 13.2 0.1 11 6.2 0.1 2.6 2 0 0 2 2 2 0 MutS family domain IV Prok-TraM PF09228.5 EDN91097.1 - 0.2 11.8 1.7 5.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Glyco_hydro_12 PF01670.11 EDN91098.1 - 4.5e-32 110.9 0.5 4.5e-32 110.9 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EDN91098.1 - 0.036 14.2 1.0 0.036 14.2 0.7 3.3 1 1 2 3 3 3 0 Phage holin Ribosomal_S19e PF01090.14 EDN91099.1 - 3.3e-55 185.3 0.2 3.7e-55 185.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HD PF01966.17 EDN91101.1 - 0.0012 18.8 0.1 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 HD domain Glyco_hydro_92 PF07971.7 EDN91102.1 - 4.1e-141 471.0 0.7 1.9e-102 343.5 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 RVT_1 PF00078.22 EDN91104.1 - 8.7e-35 120.0 1.7 1.6e-34 119.1 1.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN91104.1 - 7.4e-21 73.9 0.2 2.2e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN91104.1 - 1.4e-14 54.5 0.5 5.8e-14 52.5 0.1 2.3 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EDN91104.1 - 0.00028 20.8 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDN91104.1 - 0.061 13.0 0.3 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_60s PF00428.14 EDN91105.1 - 0.0031 17.8 7.4 0.0031 17.8 5.1 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Glyco_hydro_10 PF00331.15 EDN91106.1 - 6.5e-101 337.5 0.7 7.7e-101 337.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SLT PF01464.15 EDN91110.1 - 0.00044 19.7 0.0 0.0019 17.6 0.0 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain Glyco_hydro_26 PF02156.10 EDN91111.1 - 2e-10 40.6 0.1 3.6e-10 39.8 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Epimerase PF01370.16 EDN91112.1 - 3.2e-22 79.1 0.0 4.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN91112.1 - 6.3e-14 51.3 0.0 1.5e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN91112.1 - 1.6e-12 47.8 0.1 3.4e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDN91112.1 - 3.6e-11 42.4 0.0 2.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EDN91112.1 - 5.4e-05 23.1 0.0 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EDN91112.1 - 0.00063 19.0 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDN91112.1 - 0.0052 15.7 0.0 0.0094 14.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EDN91112.1 - 0.031 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_71 PF03659.9 EDN91113.1 - 1.2e-56 191.9 2.3 1.8e-56 191.2 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 EDN91114.1 - 9.4e-10 37.4 0.1 9.4e-10 37.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Vps16_N PF04841.8 EDN91117.1 - 5.7e-83 278.7 0.0 3.5e-75 253.0 0.0 2.3 1 1 1 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.7 EDN91117.1 - 3.2e-79 266.1 0.1 4.7e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 EDN91118.1 - 1.7e-14 53.6 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EDN91118.1 - 2.7e-06 27.1 9.5 4.4e-06 26.4 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN91118.1 - 0.018 15.1 3.9 0.033 14.2 2.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN91118.1 - 0.02 14.5 8.1 0.034 13.7 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDN91118.1 - 0.026 14.2 5.0 0.047 13.3 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EDN91118.1 - 0.029 14.0 5.6 0.069 12.8 3.9 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.9 EDN91118.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-Apc11 PF12861.2 EDN91118.1 - 0.16 11.8 3.1 0.27 11.0 2.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EDN91118.1 - 4.5 7.3 6.1 8.3 6.5 4.2 1.4 1 0 0 1 1 1 0 RING-like domain Peptidase_M16 PF00675.15 EDN91119.1 - 4.6e-45 153.0 0.0 7.7e-44 149.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDN91119.1 - 4.3e-40 137.3 0.0 4.3e-38 130.8 0.0 3.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain Disulph_isomer PF06491.6 EDN91119.1 - 0.033 14.0 1.1 0.27 11.0 0.0 2.5 3 0 0 3 3 3 0 Disulphide isomerase Init_tRNA_PT PF04179.7 EDN91120.1 - 6.4e-125 417.5 0.1 3e-78 263.7 0.0 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase Nha1_C PF08619.5 EDN91122.1 - 7.4e-105 351.7 41.2 2.8e-104 349.8 28.6 1.9 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EDN91122.1 - 2.9e-68 230.1 18.5 3.5e-68 229.8 12.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.1 EDN91122.1 - 0.033 13.9 0.4 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 FlgD Ig-like domain YrhC PF14143.1 EDN91122.1 - 0.18 11.7 1.3 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 YrhC-like protein Nucleo_P87 PF07267.6 EDN91122.1 - 10 4.6 7.7 16 3.9 5.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Dynamin_N PF00350.18 EDN91123.1 - 7.6e-17 61.6 0.1 1.7e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EDN91123.1 - 8.7e-09 35.3 0.0 3.2e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN91123.1 - 7.6e-07 28.7 0.9 4.4e-06 26.2 0.8 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 EDN91123.1 - 0.019 13.8 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2205 PF10224.4 EDN91123.1 - 0.024 14.2 0.2 0.097 12.2 0.1 2.1 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) AAA_18 PF13238.1 EDN91123.1 - 0.057 13.7 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EDN91123.1 - 0.057 13.9 0.2 0.71 10.3 0.1 2.8 2 1 0 2 2 2 0 Miro-like protein MitMem_reg PF13012.1 EDN91123.1 - 0.16 12.0 3.1 11 6.1 0.0 3.6 4 1 0 4 4 4 0 Maintenance of mitochondrial structure and function Snf7 PF03357.16 EDN91124.1 - 1.8e-38 131.6 20.9 2e-38 131.4 14.0 1.3 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 EDN91124.1 - 0.0013 18.2 5.7 0.0022 17.4 3.9 1.4 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway V_ATPase_I PF01496.14 EDN91124.1 - 0.011 13.6 4.2 0.014 13.3 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 EDN91124.1 - 0.019 14.9 20.0 1.2 9.1 8.4 2.1 1 1 1 2 2 2 0 YlqD protein Peptidase_S46 PF10459.4 EDN91124.1 - 0.48 8.7 7.8 0.58 8.5 5.4 1.1 1 0 0 1 1 1 0 Peptidase S46 PP2C PF00481.16 EDN91125.1 - 4.5e-63 213.0 0.1 8.1e-51 172.8 0.1 3.1 2 1 1 3 3 3 3 Protein phosphatase 2C DUF4202 PF13875.1 EDN91127.1 - 1.1e-68 230.5 0.1 1.2e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) TPR_2 PF07719.12 EDN91127.1 - 0.037 13.9 0.1 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SPAM PF02090.10 EDN91127.1 - 0.068 13.1 0.3 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Sas10_Utp3 PF04000.10 EDN91128.1 - 1.8 8.8 5.8 4.5 7.5 1.7 2.6 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Syntaxin PF00804.20 EDN91128.1 - 7.1 6.8 16.7 1.9 8.6 2.7 2.8 3 0 0 3 3 3 0 Syntaxin Myb_DNA-bind_6 PF13921.1 EDN91129.1 - 3.8e-05 23.7 9.8 0.0018 18.3 3.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN91129.1 - 0.0021 18.0 3.6 0.019 15.0 0.3 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_L1 PF00687.16 EDN91132.1 - 2.7e-51 174.0 0.7 3.2e-51 173.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ligase_CoA PF00549.14 EDN91133.1 - 0.097 12.2 0.0 0.097 12.2 0.0 1.0 1 0 0 1 1 1 0 CoA-ligase MFS_1 PF07690.11 EDN91134.1 - 0.00015 20.5 38.1 0.0017 17.1 24.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily 14-3-3 PF00244.15 EDN91135.1 - 5.5e-11 41.9 0.1 6.1e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 14-3-3 protein DUF605 PF04652.11 EDN91137.1 - 0.65 9.3 8.2 0.76 9.1 5.7 1.1 1 0 0 1 1 1 0 Vta1 like Skp1 PF01466.14 EDN91140.1 - 8.9e-40 134.5 2.3 8.9e-40 134.5 1.6 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EDN91140.1 - 2.1e-20 72.5 0.0 4.7e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ribosomal_L39 PF00832.15 EDN91141.1 - 2.2e-21 74.9 9.3 2.5e-21 74.8 6.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EDN91141.1 - 0.16 11.4 0.8 0.19 11.2 0.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Arf PF00025.16 EDN91142.1 - 4e-74 247.6 0.0 4.9e-74 247.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN91142.1 - 4.1e-12 45.6 0.0 4.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EDN91142.1 - 2.9e-11 42.6 1.2 1.8e-07 30.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EDN91142.1 - 5e-11 42.2 0.0 6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EDN91142.1 - 9e-09 34.8 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN91142.1 - 2.6e-08 34.3 0.0 3.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN91142.1 - 2.3e-06 27.5 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN91142.1 - 9.9e-06 25.1 0.0 0.0014 18.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EDN91142.1 - 0.02 14.1 0.5 0.069 12.4 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EDN91142.1 - 0.095 13.1 0.2 0.26 11.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Catalase PF00199.14 EDN91144.1 - 8.8e-187 620.4 1.6 1.1e-186 620.1 1.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN91144.1 - 1.3e-11 44.1 0.4 3.8e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive HCO3_cotransp PF00955.16 EDN91146.1 - 3.3e-50 171.2 17.0 4.8e-36 124.4 4.3 3.0 1 1 2 3 3 3 3 HCO3- transporter family Abhydrolase_5 PF12695.2 EDN91147.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN91147.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EDN91147.1 - 0.00015 21.1 0.0 0.00031 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDN91147.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN91147.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 EDN91147.1 - 0.063 12.5 0.0 0.18 11.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 EDN91147.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) CAF-1_p150 PF11600.3 EDN91147.1 - 0.79 9.0 34.5 0.03 13.7 19.2 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4661 PF15576.1 EDN91147.1 - 3 7.4 6.2 7.1 6.1 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Syndecan PF01034.15 EDN91148.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 EDN91148.1 - 1 8.7 7.4 0.073 12.3 0.3 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fungal_trans PF04082.13 EDN91149.1 - 6.9e-30 103.7 0.0 1.3e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain BNIP3 PF06553.7 EDN91149.1 - 0.29 10.4 3.9 1.5 8.1 0.2 2.3 2 0 0 2 2 2 0 BNIP3 Peptidase_M41 PF01434.13 EDN91150.1 - 8e-75 250.9 0.1 1.2e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDN91150.1 - 5.5e-42 143.0 0.0 1.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDN91150.1 - 7.9e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EDN91150.1 - 0.0016 18.1 0.0 0.0075 15.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN91150.1 - 0.0025 17.9 0.5 0.12 12.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN91150.1 - 0.0069 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN91150.1 - 0.0089 16.0 0.2 0.14 12.1 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EDN91150.1 - 0.0093 15.6 1.4 0.017 14.8 0.3 1.9 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EDN91150.1 - 0.01 14.5 0.1 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Preseq_ALAS PF09029.5 EDN91150.1 - 0.019 14.9 0.2 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence AAA_2 PF07724.9 EDN91150.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EDN91150.1 - 0.027 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDN91150.1 - 0.041 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDN91150.1 - 0.055 12.5 0.1 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EDN91150.1 - 0.07 13.9 0.0 0.2 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN91150.1 - 0.26 10.6 4.7 0.18 11.2 0.2 3.0 4 1 1 5 5 5 0 AAA domain DUF964 PF06133.6 EDN91151.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) ABA_GPCR PF12430.3 EDN91153.1 - 6.9e-52 175.4 8.0 1.7e-51 174.1 3.3 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EDN91153.1 - 3.6e-22 78.1 0.0 1.6e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) UPF0261 PF06792.6 EDN91154.1 - 6.5e-144 479.3 0.0 7.5e-144 479.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EDN91155.1 - 4.9e-132 438.9 0.7 5.7e-132 438.7 0.5 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EDN91155.1 - 0.00031 19.9 1.0 0.0005 19.3 0.1 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase PcrB PF01884.12 EDN91155.1 - 0.023 13.9 3.6 3.3 6.8 0.6 2.8 2 1 1 3 3 3 0 PcrB family CinA PF02464.12 EDN91155.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein Methyltransf_28 PF02636.12 EDN91156.1 - 1.9e-64 217.4 0.0 2.5e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 EDN91157.1 - 3.7e-62 209.8 0.0 5.3e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91157.1 - 1.8e-28 99.2 0.0 2.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN91157.1 - 0.00025 20.0 0.0 0.00047 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN91157.1 - 0.015 15.0 2.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family AKAP2_C PF15304.1 EDN91158.1 - 0.004 16.8 4.9 0.0047 16.5 3.4 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus DUF2413 PF10310.4 EDN91158.1 - 0.47 9.1 9.5 0.66 8.7 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 EDN91158.1 - 0.58 8.3 12.0 0.66 8.1 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Inp1 PF12634.2 EDN91158.1 - 3.5 7.2 7.0 1.1 8.9 1.7 2.1 1 1 1 2 2 2 0 Inheritance of peroxisomes protein 1 Kin17_mid PF10357.4 EDN91162.1 - 3.3e-50 168.9 1.4 3.3e-50 168.9 1.0 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EDN91162.1 - 1.5e-05 24.9 0.4 1.5e-05 24.9 0.3 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN91162.1 - 4.6e-05 23.4 0.8 0.0001 22.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN91162.1 - 0.0049 16.9 2.2 0.023 14.7 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PLATZ PF04640.9 EDN91162.1 - 0.16 12.2 0.4 0.5 10.6 0.1 1.9 2 0 0 2 2 2 0 PLATZ transcription factor Spt4 PF06093.8 EDN91163.1 - 2e-25 88.4 0.0 2.8e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EDN91163.1 - 0.06 13.1 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein DUF3384 PF11864.3 EDN91165.1 - 9.4e-115 383.7 1.8 1.8e-114 382.7 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EDN91165.1 - 3.8e-54 182.9 0.0 9.5e-54 181.6 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EDN91165.1 - 2.9e-37 128.5 5.4 1.8e-32 112.8 0.1 4.1 4 0 0 4 4 4 3 Tuberin CAS_CSE1 PF03378.10 EDN91166.1 - 2.7e-182 605.9 0.4 7.9e-182 604.3 0.1 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EDN91166.1 - 1.4e-158 527.2 1.6 2.1e-158 526.7 1.1 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EDN91166.1 - 3.2e-12 46.1 0.0 1.4e-11 44.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EDN91166.1 - 0.015 15.2 6.1 0.39 10.6 0.3 4.9 4 2 2 6 6 6 0 Exportin 1-like protein V-ATPase_H_N PF03224.9 EDN91166.1 - 0.029 13.4 0.5 0.13 11.3 0.0 2.3 2 2 0 2 2 2 0 V-ATPase subunit H UNC45-central PF11701.3 EDN91166.1 - 0.066 12.8 0.1 1 9.0 0.0 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Paf67 PF10255.4 EDN91167.1 - 2e-155 517.6 0.1 2.4e-155 517.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EDN91167.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 EDN91168.1 - 3.1e-09 37.1 0.2 3.1e-09 37.1 0.1 2.4 2 2 0 2 2 2 1 Universal stress protein family Xan_ur_permease PF00860.15 EDN91169.1 - 1.8e-20 72.7 24.9 4.4e-19 68.2 17.3 2.0 1 1 0 1 1 1 1 Permease family AA_kinase PF00696.23 EDN91171.1 - 1.4e-39 136.0 0.2 2.4e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EDN91171.1 - 3e-14 52.1 0.4 9.3e-08 31.4 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EDN91171.1 - 4.6e-13 48.4 5.7 9.8e-10 37.8 0.3 2.5 2 0 0 2 2 2 2 ACT domain RFX_DNA_binding PF02257.10 EDN91172.1 - 2.8e-30 104.2 0.1 6.9e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EDN91173.1 - 9.1e-31 105.4 7.2 9.1e-31 105.4 5.0 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2207 PF09972.4 EDN91173.1 - 0.45 9.0 4.8 0.51 8.8 3.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mid1 PF12929.2 EDN91174.1 - 8.3e-138 459.6 5.4 1e-137 459.4 3.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EDN91174.1 - 0.56 10.5 6.0 7.3 6.9 2.4 2.6 2 1 0 2 2 2 0 Fz domain Fork_head PF00250.13 EDN91177.1 - 8.6e-34 115.4 0.4 1.6e-33 114.6 0.3 1.3 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EDN91180.1 - 3.1e-64 216.6 0.0 4.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91180.1 - 2e-27 95.9 0.0 3e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN91180.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN91180.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EDN91180.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family TFIIA PF03153.8 EDN91180.1 - 2.3 8.0 12.5 3.2 7.5 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRRNT PF01462.13 EDN91181.1 - 0.019 14.4 1.2 0.032 13.7 0.8 1.3 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TAXi_N PF14543.1 EDN91181.1 - 0.13 12.1 1.9 0.12 12.2 1.3 1.1 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DUF3091 PF11291.3 EDN91181.1 - 0.37 10.7 4.4 0.16 11.9 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) PBP1_TM PF14812.1 EDN91183.1 - 0.11 12.7 0.3 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_L_2 PF13656.1 EDN91185.1 - 6.7e-07 28.6 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDN91185.1 - 0.00057 18.9 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EDN91186.1 - 1.6e-06 28.5 0.4 1.9e-06 28.3 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EDN91186.1 - 3.9e-05 23.7 0.2 7.9e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN91186.1 - 8.2e-05 22.3 0.2 0.00022 20.9 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DUF651 PF04895.7 EDN91186.1 - 0.1 12.2 0.2 0.22 11.1 0.1 1.5 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF651) Vps51 PF08700.6 EDN91186.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 1 1 2 2 2 0 Vps51/Vps67 G10 PF01125.12 EDN91187.1 - 4e-57 191.8 9.3 4.5e-57 191.6 6.4 1.0 1 0 0 1 1 1 1 G10 protein Pkinase PF00069.20 EDN91188.1 - 2.7e-51 174.2 0.0 7e-51 172.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91188.1 - 3.9e-29 101.5 0.0 3.3e-27 95.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN91188.1 - 3.4e-07 29.5 0.0 3.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDN91188.1 - 0.00067 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 EDN91189.1 - 4.5e-20 71.8 0.0 6.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDN91189.1 - 0.094 12.5 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Peroxin-3 PF04882.7 EDN91190.1 - 1.4e-155 518.2 0.0 1.6e-155 518.0 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EDN91191.1 - 1.7e-44 151.3 0.5 1.9e-44 151.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 EDN91191.1 - 0.036 13.6 0.2 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain La PF05383.12 EDN91192.1 - 0.12 12.2 0.0 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 La domain zf-C2H2 PF00096.21 EDN91192.1 - 0.8 10.1 14.5 0.77 10.2 0.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.7 EDN91192.1 - 1.4 7.3 5.6 1.1 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) EST1_DNA_bind PF10373.4 EDN91193.1 - 1.9e-37 129.0 0.0 1.8e-25 89.7 0.0 2.6 1 1 1 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.4 EDN91193.1 - 1.3e-19 70.5 2.9 2.8e-19 69.4 2.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EDN91193.1 - 0.00028 20.4 0.5 0.00084 18.9 0.3 1.8 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EDN91193.1 - 0.072 13.7 2.0 0.21 12.2 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PfkB PF00294.19 EDN91194.1 - 4e-66 223.2 0.2 4.4e-66 223.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDN91194.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L2_C PF03947.13 EDN91195.1 - 7.4e-38 129.2 3.7 7.4e-38 129.2 2.6 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDN91195.1 - 4.6e-14 52.1 0.0 9.7e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Nop14 PF04147.7 EDN91196.1 - 0.00028 19.0 15.0 0.0004 18.4 10.4 1.2 1 0 0 1 1 1 1 Nop14-like family WHIM1 PF15612.1 EDN91196.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CDC45 PF02724.9 EDN91196.1 - 9 4.1 11.8 17 3.2 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF1770 PF08589.5 EDN91197.1 - 6.4e-33 113.3 1.7 8.2e-33 112.9 1.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) MARVEL PF01284.18 EDN91200.1 - 6.2e-14 52.0 5.1 7.4e-14 51.7 3.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain UreF PF01730.11 EDN91201.1 - 2.3e-08 34.2 0.0 3.9e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 UreF RRM_5 PF13893.1 EDN91202.1 - 1.7e-08 34.1 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN91202.1 - 1.9e-08 33.7 0.0 3.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN91202.1 - 2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN91202.1 - 0.00027 20.6 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EDN91202.1 - 0.019 14.6 0.7 0.034 13.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 EDN91203.1 - 7.3e-68 228.5 0.0 1.1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91203.1 - 2.1e-47 161.3 0.0 3.6e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EDN91203.1 - 1.2e-29 102.2 0.0 2.9e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EDN91203.1 - 1.5e-16 60.2 0.1 3.2e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDN91203.1 - 9e-16 57.4 0.1 2.1e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EDN91203.1 - 8.8e-13 48.5 0.1 1.7e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EDN91203.1 - 6.7e-08 31.8 0.0 6.4e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 EDN91203.1 - 0.00013 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EDN91203.1 - 0.073 13.1 0.6 0.2 11.6 0.4 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Pep3_Vps18 PF05131.9 EDN91205.1 - 2.4e-51 173.0 0.0 6e-51 171.7 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EDN91205.1 - 2.7e-10 39.9 3.1 6.1e-07 29.1 0.0 3.5 2 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EDN91205.1 - 0.00021 21.0 1.2 0.00043 20.0 0.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN91205.1 - 0.00043 19.9 0.3 0.00096 18.8 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DNA_pol3_theta PF06440.6 EDN91205.1 - 0.01 15.3 0.0 0.053 13.1 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, theta subunit Vps39_2 PF10367.4 EDN91205.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 EDN91205.1 - 0.028 14.4 0.4 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.20 EDN91205.1 - 0.063 12.9 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN91205.1 - 0.13 12.3 0.8 0.3 11.1 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MaoC_dehydratas PF01575.14 EDN91208.1 - 0.00035 19.9 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.13 EDN91209.1 - 2.1e-64 216.4 0.0 3.8e-64 215.5 0.0 1.4 2 0 0 2 2 2 1 Prephenate dehydratase ACT PF01842.20 EDN91209.1 - 7.5e-05 22.1 0.0 0.0002 20.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.10 EDN91210.1 - 1e-46 158.5 0.1 1.9e-46 157.6 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDN91210.1 - 5e-40 136.2 0.6 1.1e-39 135.1 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDN91210.1 - 2.5e-28 98.2 0.0 4.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 AAA_14 PF13173.1 EDN91211.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain CD4-extracel PF09191.5 EDN91211.1 - 0.029 14.4 0.8 0.15 12.1 0.2 2.1 2 0 0 2 2 2 0 CD4, extracellular AAA_18 PF13238.1 EDN91211.1 - 0.038 14.3 0.2 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDN91211.1 - 0.12 13.1 0.0 0.46 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EDN91214.1 - 1.6e-14 54.3 0.4 1.9e-14 54.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2138 PF09909.4 EDN91214.1 - 0.039 12.0 0.0 0.049 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Orthoreo_P17 PF07272.6 EDN91214.1 - 0.098 12.4 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus P17 protein PLDc_2 PF13091.1 EDN91216.1 - 4.8e-05 23.1 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.17 EDN91216.1 - 0.00016 21.3 0.3 0.0021 17.7 0.0 2.6 2 1 0 2 2 2 1 Phospholipase D Active site motif PsbJ PF01788.12 EDN91216.1 - 0.18 11.3 1.6 0.42 10.1 1.1 1.6 1 0 0 1 1 1 0 PsbJ zf-C3HC4_3 PF13920.1 EDN91217.1 - 0.019 14.6 2.1 0.026 14.1 1.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.4 EDN91217.1 - 0.062 13.0 0.3 0.072 12.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) ArgJ PF01960.13 EDN91218.1 - 5.2e-126 420.1 0.2 2.2e-95 319.3 0.0 2.0 1 1 1 2 2 2 2 ArgJ family HGTP_anticodon2 PF12745.2 EDN91219.1 - 1.4e-79 267.0 0.1 1.4e-79 267.0 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EDN91219.1 - 1.5e-74 250.4 0.0 1.1e-37 129.6 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91219.1 - 6.6e-51 172.8 0.0 1.5e-21 76.6 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EDN91219.1 - 1.1e-14 54.2 0.7 1.1e-14 54.2 0.5 2.6 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.1 EDN91219.1 - 1.2e-14 54.1 0.7 2.3e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EDN91219.1 - 0.00033 20.4 5.6 0.052 13.2 0.1 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN91219.1 - 0.0013 17.7 0.0 0.45 9.4 0.0 2.7 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 EDN91219.1 - 0.12 11.1 0.0 0.87 8.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 EDN91220.1 - 6.5e-44 150.2 0.0 8.4e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EDN91221.1 - 1.6e-72 244.4 4.9 2.1e-72 244.0 3.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN91221.1 - 5.4e-12 45.9 0.9 5.4e-12 45.9 0.7 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDN91221.1 - 4.5e-08 33.4 1.2 0.0057 17.1 0.3 3.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDN91221.1 - 6.6e-08 32.2 0.1 2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal ABC_tran PF00005.22 EDN91222.1 - 4e-53 179.4 0.1 6.8e-30 104.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EDN91222.1 - 1e-46 159.6 31.9 2.8e-24 85.9 6.2 3.8 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EDN91222.1 - 1.9e-08 33.7 2.9 0.0012 18.0 0.3 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN91222.1 - 7.8e-08 32.6 0.0 0.24 11.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDN91222.1 - 2.2e-06 28.1 0.0 0.0022 18.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN91222.1 - 1.1e-05 24.9 0.0 0.0089 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EDN91222.1 - 0.00017 20.5 0.1 0.0087 14.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EDN91222.1 - 0.00023 20.7 0.1 0.95 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_29 PF13555.1 EDN91222.1 - 0.00029 20.2 0.1 0.65 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EDN91222.1 - 0.0003 21.0 0.5 1.7 8.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EDN91222.1 - 0.00033 20.5 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EDN91222.1 - 0.00049 20.8 0.1 2.5 8.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN91222.1 - 0.00075 19.6 1.3 3.9 7.6 0.2 3.5 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDN91222.1 - 0.00078 18.6 0.0 0.98 8.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EDN91222.1 - 0.00097 18.6 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EDN91222.1 - 0.00098 18.2 1.0 0.24 10.4 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 EDN91222.1 - 0.001 19.5 0.2 3.1 8.3 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EDN91222.1 - 0.0012 18.6 1.1 0.079 12.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EDN91222.1 - 0.0014 18.6 0.1 0.99 9.3 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EDN91222.1 - 0.0094 15.3 0.0 2.7 7.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein MobB PF03205.9 EDN91222.1 - 0.022 14.4 0.3 8.2 6.1 0.0 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDN91222.1 - 0.023 14.9 1.0 6.6 6.9 0.1 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDN91222.1 - 0.037 13.6 0.2 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EDN91222.1 - 0.053 12.1 0.2 4 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 EDN91222.1 - 0.074 12.8 2.4 1.6 8.5 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EDN91222.1 - 0.18 11.6 0.0 9.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDN91222.1 - 0.45 9.9 2.1 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NdhL PF10716.4 EDN91222.1 - 1.8 8.3 9.9 0.2 11.4 0.4 3.7 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit SecY PF00344.15 EDN91224.1 - 1.3e-96 323.5 12.0 1.6e-96 323.2 8.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDN91224.1 - 1e-18 66.5 0.6 7.8e-18 63.6 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p E1-E2_ATPase PF00122.15 EDN91225.1 - 7.4e-49 165.8 0.5 7.4e-49 165.8 0.3 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN91225.1 - 6.2e-34 117.1 6.8 6.2e-34 117.1 4.7 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN91225.1 - 2e-29 103.5 0.0 3.3e-28 99.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN91225.1 - 5.9e-17 62.4 0.0 2.6e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN91225.1 - 3.1e-14 52.7 0.0 7.5e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDN91225.1 - 2.4e-10 39.7 0.0 8.4e-10 37.9 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN91225.1 - 0.00047 19.8 0.3 0.001 18.6 0.1 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CcmH PF03918.9 EDN91225.1 - 0.038 12.9 0.7 0.1 11.6 0.3 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3753 PF12575.3 EDN91225.1 - 6.5 6.6 8.8 1.7 8.4 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) IPPT PF01715.12 EDN91226.1 - 9.2e-49 165.7 0.3 5.3e-48 163.2 0.2 2.0 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 EDN91226.1 - 8.6e-05 22.8 0.7 0.027 14.7 0.1 3.2 1 1 1 2 2 2 1 AAA domain IPT PF01745.11 EDN91226.1 - 0.0001 21.5 0.0 0.00026 20.2 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.1 EDN91226.1 - 0.00016 21.6 0.2 0.014 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDN91226.1 - 0.00034 21.4 0.4 0.0032 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN91226.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN91226.1 - 0.021 15.0 0.0 0.71 10.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDN91226.1 - 0.044 13.9 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EDN91226.1 - 0.063 13.4 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-met PF12874.2 EDN91226.1 - 0.11 12.7 0.5 0.11 12.7 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Hpr_kinase_C PF07475.7 EDN91226.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 EDN91226.1 - 0.16 11.7 0.0 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain ORC2 PF04084.9 EDN91227.1 - 2.3e-113 378.3 0.0 3e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Cut12 PF11500.3 EDN91228.1 - 1.1e-45 155.0 10.6 1.1e-45 155.0 7.3 3.5 2 1 2 4 4 4 1 Spindle pole body formation-associated protein DUF4094 PF13334.1 EDN91228.1 - 6.9 7.1 25.9 7.5 7.0 5.5 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) UQ_con PF00179.21 EDN91229.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN91229.1 - 0.0032 17.2 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B UBA_4 PF14555.1 EDN91231.1 - 1.1e-05 24.8 0.2 2.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 EDN91231.1 - 0.062 12.8 4.6 0.043 13.3 1.4 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif Hormone_1 PF00103.15 EDN91231.1 - 0.062 12.6 0.9 0.13 11.5 0.7 1.5 1 0 0 1 1 1 0 Somatotropin hormone family DUF948 PF06103.6 EDN91231.1 - 0.069 13.0 0.5 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DnaJ PF00226.26 EDN91232.1 - 6.9e-26 89.7 4.3 1.2e-25 89.0 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDN91232.1 - 3.2e-22 78.2 2.0 3.3e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain Pkinase PF00069.20 EDN91234.1 - 3e-70 236.3 0.1 3e-70 236.3 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91234.1 - 2.8e-53 180.6 0.1 5.1e-53 179.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDN91234.1 - 5.6e-22 77.9 0.5 2e-21 76.1 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EDN91234.1 - 6.1e-08 31.9 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EDN91234.1 - 2.6e-06 27.6 0.4 7.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 EDN91234.1 - 0.0022 17.8 4.2 0.0034 17.1 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 EDN91235.1 - 1.1e-65 220.4 0.0 2.2e-65 219.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN91235.1 - 9.2e-20 70.3 2.0 3e-19 68.7 0.0 2.9 3 1 1 4 4 4 1 Anticodon binding domain Brix PF04427.13 EDN91236.1 - 3.3e-39 134.5 0.0 4.6e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain RRN3 PF05327.6 EDN91236.1 - 0.7 7.9 5.1 0.97 7.4 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BORG_CEP PF14957.1 EDN91236.1 - 1.9 9.3 7.3 0.29 12.0 2.1 1.7 2 0 0 2 2 2 0 Cdc42 effector MFS_1 PF07690.11 EDN91238.1 - 5.8e-30 104.1 22.4 5.8e-30 104.1 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3353 PF11833.3 EDN91238.1 - 0.96 8.8 5.9 1.8 7.9 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3353) Polysacc_deac_1 PF01522.16 EDN91239.1 - 6e-26 90.5 0.0 1.1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EDN91239.1 - 1e-18 67.0 91.6 5.6e-05 23.0 12.6 4.8 4 0 0 4 4 4 4 Chitin recognition protein Methyltransf_PK PF05891.7 EDN91240.1 - 1.4e-78 263.1 0.0 1.6e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EDN91240.1 - 1.6e-07 31.1 0.0 4.4e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN91240.1 - 0.0061 17.1 0.0 0.019 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN91240.1 - 0.011 16.1 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EDN91240.1 - 0.09 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDN91241.1 - 1e-14 54.5 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN91241.1 - 1.7e-06 28.4 0.0 2.8e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN91241.1 - 5e-06 26.9 0.0 2.9e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN91241.1 - 5.7e-06 25.9 0.0 5.6e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN91241.1 - 8.2e-05 23.1 0.2 0.0023 18.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN91241.1 - 0.0003 19.9 0.0 0.049 12.7 0.0 2.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDN91241.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Epimerase PF01370.16 EDN91243.1 - 7.5e-57 192.4 0.0 1e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN91243.1 - 2.2e-23 82.6 0.0 2.2e-22 79.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN91243.1 - 1.1e-21 76.9 0.1 6.3e-21 74.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EDN91243.1 - 1.9e-20 72.6 0.0 4.2e-20 71.6 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN91243.1 - 6.3e-20 71.2 0.0 9.1e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDN91243.1 - 1.8e-07 31.3 0.0 3.6e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDN91243.1 - 0.002 18.0 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase TPT PF03151.11 EDN91245.1 - 9.5e-16 57.8 14.8 9.5e-16 57.8 10.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDN91245.1 - 0.0004 20.4 13.2 0.0004 20.4 9.2 2.9 2 2 1 3 3 3 1 EamA-like transporter family CRPA PF05745.6 EDN91245.1 - 0.056 13.2 0.7 0.056 13.2 0.5 2.1 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tuberculin PF12198.3 EDN91245.1 - 0.1 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Theoretical tuberculin protein FAD_binding_3 PF01494.14 EDN91246.1 - 2.3e-16 59.8 2.4 7.9e-12 44.8 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN91246.1 - 1.4e-05 24.2 0.0 0.058 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN91246.1 - 0.00066 20.0 0.7 0.0061 16.9 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase N_Asn_amidohyd PF14736.1 EDN91246.1 - 0.076 11.8 0.5 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase DUF1449 PF07290.6 EDN91247.1 - 0.065 12.5 0.0 0.075 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Btz PF09405.5 EDN91249.1 - 0.029 14.4 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Flu_PA PF00603.12 EDN91252.1 - 0.2 9.6 18.4 0.26 9.2 12.7 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA CDC45 PF02724.9 EDN91252.1 - 1 7.3 22.9 1.2 7.0 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 EDN91252.1 - 9.4 4.5 52.7 12 4.2 36.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1347 PF07079.6 EDN91253.1 - 0.2 9.8 0.1 0.31 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) FR47 PF08445.5 EDN91254.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EDN91254.1 - 0.0061 16.7 0.0 0.0073 16.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN91254.1 - 0.0097 15.9 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN91254.1 - 0.06 13.5 0.0 0.065 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN91254.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-C3HC4 PF00097.20 EDN91255.1 - 8.3e-08 31.7 4.1 8.3e-08 31.7 2.8 5.1 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN91255.1 - 4.1e-07 29.7 5.8 4.1e-07 29.7 4.0 4.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN91255.1 - 6.9e-06 25.9 5.2 6.9e-06 25.9 3.6 4.9 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDN91255.1 - 7.2e-06 25.6 0.7 7.2e-06 25.6 0.5 3.0 4 0 0 4 4 4 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EDN91255.1 - 1.1e-05 25.0 3.1 1.1e-05 25.0 2.1 5.1 5 2 0 5 5 5 1 zinc-RING finger domain SH3_9 PF14604.1 EDN91255.1 - 0.0004 19.9 0.3 0.0004 19.9 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_UBOX PF13445.1 EDN91255.1 - 0.0013 18.4 1.8 0.0036 16.9 1.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SH3_1 PF00018.23 EDN91255.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_4 PF15227.1 EDN91255.1 - 0.0027 17.5 6.0 0.0027 17.5 4.2 5.0 5 3 1 6 6 6 1 zinc finger of C3HC4-type, RING NUDE_C PF04880.8 EDN91256.1 - 0.0071 16.7 5.6 0.016 15.6 3.9 1.5 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF2723 PF11028.3 EDN91256.1 - 0.075 12.5 2.0 0.39 10.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) LON PF02190.11 EDN91258.1 - 1.1e-07 31.7 0.0 2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain ZZ PF00569.12 EDN91259.1 - 0.19 11.2 2.1 0.36 10.4 1.5 1.5 1 1 0 1 1 1 0 Zinc finger, ZZ type efThoc1 PF11957.3 EDN91261.1 - 2.8e-176 586.8 5.3 3.7e-176 586.4 3.6 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EDN91262.1 - 1.8e-27 96.0 0.0 3.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDN91262.1 - 7.8e-24 84.5 0.0 1.6e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN91262.1 - 7.1e-11 41.7 0.0 4.2e-09 36.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDN91262.1 - 1.6e-05 24.5 0.0 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EDN91262.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDN91262.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN91262.1 - 0.0009 19.4 0.0 0.0026 17.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EDN91262.1 - 0.001 18.6 0.1 0.057 12.9 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDN91262.1 - 0.0013 18.9 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN91262.1 - 0.0031 17.5 0.1 0.055 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.24 EDN91262.1 - 0.0038 16.7 0.0 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.1 EDN91262.1 - 0.0073 16.1 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN91262.1 - 0.011 14.7 0.2 0.045 12.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 EDN91262.1 - 0.014 14.3 0.9 0.024 13.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EDN91262.1 - 0.023 15.4 0.0 0.13 13.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN91262.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase UvrD_C_2 PF13538.1 EDN91262.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EDN91262.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDN91262.1 - 0.072 12.9 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EDN91262.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EDN91262.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 EDN91262.1 - 0.14 11.0 0.0 7.4 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.17 EDN91262.1 - 0.2 11.8 0.0 0.55 10.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Homeobox PF00046.24 EDN91266.1 - 8.5e-17 60.5 3.2 8.5e-17 60.5 2.2 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EDN91266.1 - 0.056 13.1 1.0 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Sigma70_ner PF04546.8 EDN91266.1 - 0.11 12.1 4.4 0.21 11.1 3.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Prothymosin PF03247.9 EDN91266.1 - 0.18 11.9 4.9 6.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.9 EDN91267.1 - 0.0031 17.0 8.5 0.0034 16.9 5.9 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Angiomotin_C PF12240.3 EDN91267.1 - 0.053 13.0 5.2 0.062 12.7 3.6 1.1 1 0 0 1 1 1 0 Angiomotin C terminal Gpi16 PF04113.9 EDN91267.1 - 0.12 10.4 1.2 0.12 10.3 0.8 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Hom_end_hint PF05203.11 EDN91267.1 - 0.26 10.9 3.9 0.3 10.7 2.7 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint NPR3 PF03666.8 EDN91267.1 - 0.53 8.7 7.0 0.57 8.6 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3451 PF11933.3 EDN91267.1 - 1 9.0 7.9 1.2 8.8 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) GAGA_bind PF06217.7 EDN91267.1 - 2 8.2 11.1 2.6 7.9 7.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 EDN91267.1 - 7.7 5.1 12.8 8.6 4.9 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 3HCDH_N PF02737.13 EDN91269.1 - 3.2e-53 180.0 0.2 4.1e-53 179.6 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EDN91269.1 - 1.6e-30 105.3 0.0 3.4e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDN91269.1 - 0.00044 20.1 0.1 0.00095 19.0 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EDN91269.1 - 0.00076 18.9 0.1 0.005 16.2 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EDN91269.1 - 0.0031 16.4 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EDN91269.1 - 0.014 15.1 0.2 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EDN91269.1 - 0.019 14.1 0.2 0.044 12.9 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EDN91269.1 - 0.043 14.2 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN91269.1 - 0.052 13.6 1.3 0.14 12.2 0.8 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EDN91269.1 - 0.055 13.9 0.2 0.15 12.5 0.2 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EDN91269.1 - 0.11 12.4 0.2 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain LDB19 PF13002.2 EDN91269.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like TIMELESS PF04821.9 EDN91270.1 - 1e-95 320.0 0.0 2e-95 319.0 0.0 1.5 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EDN91270.1 - 1.8e-29 103.1 0.0 1.8e-29 103.1 0.0 3.2 3 0 0 3 3 3 2 Timeless protein C terminal region DUF4062 PF13271.1 EDN91272.1 - 0.052 13.5 0.1 0.063 13.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) Glyco_hydro_18 PF00704.23 EDN91274.1 - 7.1e-46 157.2 0.0 9.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EDN91274.1 - 8e-07 28.9 14.6 8e-07 28.9 10.1 2.6 1 1 1 2 2 2 1 Chitin recognition protein Sas10 PF09368.5 EDN91275.1 - 8.2e-23 80.3 3.8 8.2e-23 80.3 2.6 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EDN91275.1 - 2.2e-16 59.8 0.5 1.2e-14 54.2 0.0 3.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Med5 PF08689.5 EDN91276.1 - 3.4e-212 706.9 0.0 1.4e-186 622.2 0.0 3.4 1 1 2 3 3 3 3 Mediator complex subunit Med5 DUF4452 PF14618.1 EDN91279.1 - 0.056 13.2 0.8 0.066 13.0 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) FMN_dh PF01070.13 EDN91283.1 - 7.6e-116 386.8 0.0 9.5e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDN91283.1 - 1.1e-17 63.5 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDN91283.1 - 1.2e-05 24.3 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDN91283.1 - 1.5e-05 24.1 1.2 0.0039 16.1 0.1 2.7 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EDN91283.1 - 0.00012 21.3 0.4 0.00046 19.4 0.2 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.13 EDN91284.1 - 3.3e-111 371.5 0.0 3.8e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EDN91284.1 - 0.00018 20.5 0.2 0.00035 19.5 0.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EDN91284.1 - 0.0077 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EDN91284.1 - 0.0084 15.3 0.1 0.74 9.0 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EDN91284.1 - 0.014 14.5 0.6 5.7 5.9 0.1 3.4 3 1 1 4 4 4 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 EDN91284.1 - 0.074 12.1 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase NDT80_PhoG PF05224.7 EDN91289.1 - 2.3e-32 112.5 0.0 4.4e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 EDN91290.1 - 5.4e-30 103.9 14.6 7.3e-30 103.5 10.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) AA_permease_2 PF13520.1 EDN91292.1 - 7.5e-62 209.2 45.0 1e-61 208.8 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN91292.1 - 5.9e-28 97.4 30.7 5.9e-28 97.4 21.3 2.2 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 EDN91293.1 - 1.8e-47 161.7 0.0 4.1e-10 38.3 0.0 6.3 2 1 4 6 6 6 6 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EDN91293.1 - 1e-43 148.7 0.0 2e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EDN91293.1 - 3.7e-16 58.7 2.6 2.1e-05 23.3 0.0 5.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDN91293.1 - 6.1e-12 45.5 0.2 1.2e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDN91293.1 - 0.00052 19.2 0.0 0.23 10.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EDN91293.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) CNH PF00780.17 EDN91294.1 - 4.3e-77 259.2 0.0 6.8e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EDN91294.1 - 1.9e-27 96.2 0.0 4.2e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EDN91294.1 - 2.8e-17 62.9 0.1 2.7e-14 53.2 0.1 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDN91294.1 - 0.00043 20.4 0.0 0.0021 18.2 0.0 2.3 1 0 0 1 1 1 1 PH domain Sod_Cu PF00080.15 EDN91296.1 - 4.7e-43 146.7 5.3 5.6e-43 146.5 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 EDN91297.1 - 5.5e-75 248.5 0.0 3.5e-24 85.1 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EDN91297.1 - 2.5e-26 91.9 0.0 8.3e-25 86.9 0.0 2.4 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EDN91297.1 - 1.9e-05 23.9 0.3 0.00015 20.9 0.0 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Methyltransf_2 PF00891.13 EDN91299.1 - 7.6e-17 61.3 0.1 2.9e-16 59.4 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EDN91299.1 - 0.032 14.0 0.1 0.085 12.7 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain Xol-1_N PF09108.5 EDN91299.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal Rrf2 PF02082.15 EDN91299.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator GST_C PF00043.20 EDN91300.1 - 5.2e-09 35.9 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN91300.1 - 2.4e-08 34.0 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN91300.1 - 3.4e-08 33.5 0.0 6.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN91300.1 - 2.2e-07 30.7 0.0 5.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDN91300.1 - 1.5e-05 25.3 0.2 5.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN91300.1 - 1.7e-05 24.5 1.7 3.4e-05 23.6 0.1 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain U6-snRNA_bdg PF10596.4 EDN91302.1 - 0.049 12.9 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 RVT_1 PF00078.22 EDN91303.1 - 7.2e-12 45.1 0.0 8.3e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN91304.1 - 1.3e-15 57.0 0.1 2.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN91304.1 - 6.9e-07 29.4 0.0 9.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transaldolase PF00923.14 EDN91306.1 - 3.5e-74 249.5 0.8 4.7e-47 160.4 0.2 2.0 1 1 1 2 2 2 2 Transaldolase MMR_HSR1 PF01926.18 EDN91308.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN91308.1 - 0.00028 20.7 0.0 0.16 11.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 EDN91308.1 - 0.00033 19.9 0.0 0.00054 19.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN91308.1 - 0.00095 18.3 0.4 0.004 16.3 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EDN91308.1 - 0.008 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 EDN91308.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDN91308.1 - 0.018 14.5 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EDN91308.1 - 0.031 15.1 0.1 0.1 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDN91308.1 - 0.033 14.1 0.0 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.11 EDN91308.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EDN91308.1 - 0.09 13.2 0.1 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_15 PF13175.1 EDN91308.1 - 0.2 10.6 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DDE_1 PF03184.14 EDN91309.1 - 0.003 16.7 0.1 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91309.1 - 0.0053 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDN91309.1 - 0.082 11.7 0.1 0.14 11.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3404) zf-CCHC PF00098.18 EDN91310.1 - 0.0025 17.6 6.0 0.0036 17.1 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDN91310.1 - 0.024 14.9 0.7 0.043 14.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EDN91310.1 - 0.033 14.5 0.3 0.047 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EDN91310.1 - 0.035 14.0 1.6 0.056 13.4 1.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 EDN91310.1 - 0.24 11.2 2.9 20 5.0 1.0 2.7 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein HTH_Tnp_Tc5 PF03221.11 EDN91311.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF2764 PF10962.3 EDN91311.1 - 0.0096 15.1 0.4 0.012 14.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2764) DDE_1 PF03184.14 EDN91311.1 - 0.07 12.2 0.2 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease AAA_14 PF13173.1 EDN91312.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 EDN91314.1 - 5.3e-05 21.1 16.0 0.00036 18.4 11.1 1.9 1 1 0 1 1 1 1 Myosin tail Jnk-SapK_ap_N PF09744.4 EDN91314.1 - 0.0084 16.1 1.6 0.0084 16.1 1.1 2.3 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 IncA PF04156.9 EDN91314.1 - 0.027 14.0 12.3 0.053 13.1 8.5 1.5 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 EDN91314.1 - 0.038 12.4 0.5 0.052 11.9 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 EDN91314.1 - 0.044 14.0 16.1 0.36 11.1 2.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) ATG16 PF08614.6 EDN91314.1 - 0.044 13.6 14.3 0.15 11.8 9.8 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EDN91314.1 - 0.15 12.4 12.0 0.16 12.3 1.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF724 PF05266.9 EDN91314.1 - 0.26 10.9 12.0 0.6 9.6 6.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.8 EDN91314.1 - 0.47 9.4 6.4 0.093 11.7 1.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein bZIP_1 PF00170.16 EDN91314.1 - 1.8 8.6 9.6 4 7.4 0.2 2.9 2 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EDN91314.1 - 2.3 7.7 16.8 6.2 6.3 0.3 4.4 1 1 2 4 4 4 0 Septum formation initiator Lge1 PF11488.3 EDN91314.1 - 2.6 8.2 12.7 9.7 6.4 1.6 4.1 3 2 0 3 3 3 0 Transcriptional regulatory protein LGE1 DivIVA PF05103.8 EDN91314.1 - 2.7 8.0 13.1 0.57 10.2 4.4 2.6 1 1 1 2 2 2 0 DivIVA protein DUF1640 PF07798.6 EDN91314.1 - 5.5 7.0 13.1 4.6e+02 0.7 9.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) APG6 PF04111.7 EDN91314.1 - 8.7 5.2 15.1 0.66 8.9 5.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 MFS_1 PF07690.11 EDN91315.1 - 3.1e-30 105.1 32.5 3.1e-30 105.1 22.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN91315.1 - 2.9e-05 22.8 30.5 0.017 13.7 8.8 3.2 1 1 1 3 3 3 3 Sugar (and other) transporter DUF4149 PF13664.1 EDN91315.1 - 0.22 11.6 7.3 1.8 8.6 1.5 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4149) MARVEL PF01284.18 EDN91316.1 - 1.2e-05 25.1 9.9 1.7e-05 24.6 6.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 EDN91316.1 - 0.011 15.3 0.7 0.017 14.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) PRCH PF03967.8 EDN91316.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF202 PF02656.10 EDN91316.1 - 1.7 8.9 5.0 19 5.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Tic20 PF09685.5 EDN91316.1 - 4.5 7.2 8.0 9.2 6.3 5.6 1.6 1 1 0 1 1 1 0 Tic20-like protein HAD_2 PF13419.1 EDN91318.1 - 2.2e-19 70.3 0.0 2.9e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN91318.1 - 2.2e-09 36.8 0.0 3.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN91318.1 - 1e-08 35.8 0.1 3.3e-08 34.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EDN91318.1 - 0.034 13.8 0.0 5.2 6.7 0.0 2.2 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase Spc42p PF11544.3 EDN91319.1 - 0.085 12.7 2.3 0.12 12.3 0.8 1.8 1 1 1 2 2 2 0 Spindle pole body component Spc42p ERM PF00769.14 EDN91319.1 - 0.11 12.0 1.6 0.15 11.5 1.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3435 PF11917.3 EDN91320.1 - 1.6e-07 30.3 0.5 1.6e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) APG6 PF04111.7 EDN91320.1 - 0.013 14.5 0.4 0.013 14.5 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EDN91320.1 - 0.16 11.5 3.9 0.065 12.8 0.5 1.8 2 0 0 2 2 2 0 IncA protein COesterase PF00135.23 EDN91322.1 - 1e-43 149.8 6.8 1.4e-38 132.9 1.5 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN91322.1 - 0.00052 19.6 0.4 0.0042 16.6 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN91322.1 - 0.049 13.3 0.6 0.091 12.5 0.4 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.23 EDN91323.1 - 1.6e-33 115.7 0.0 2.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN91323.1 - 9e-33 113.2 0.0 1.4e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EDN91323.1 - 3.9e-11 42.8 0.0 6.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN91323.1 - 2.5e-08 34.0 0.0 6.8e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EDN91323.1 - 0.00083 18.3 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EDN91323.1 - 0.0077 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 EDN91323.1 - 0.048 14.2 0.1 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 EDN91323.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Aldo_ket_red PF00248.16 EDN91324.1 - 5e-68 228.9 0.0 5.7e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 EDN91326.1 - 2.2e-33 115.2 0.0 4.6e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN91326.1 - 3.1e-24 85.1 0.0 5.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EDN91326.1 - 5.2e-08 32.6 0.0 9.6e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDN91326.1 - 6.3e-07 29.2 0.2 1.6e-05 24.6 0.1 2.9 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 EDN91326.1 - 1.1e-06 28.7 1.2 5.2e-05 23.2 0.3 3.3 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 EDN91326.1 - 2.8e-05 24.2 0.0 0.00013 22.1 0.0 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EDN91326.1 - 0.0012 17.7 0.0 0.0056 15.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.14 EDN91327.1 - 1.4e-51 175.4 0.0 1.9e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN91327.1 - 4.5e-38 130.7 0.0 7.6e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN91327.1 - 1.3e-07 30.8 0.1 0.00038 19.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN91327.1 - 5.9e-05 22.1 0.5 0.00013 21.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN91327.1 - 0.0024 17.7 0.2 0.0053 16.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN91327.1 - 0.0037 17.3 0.2 0.12 12.3 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN91327.1 - 0.0052 16.7 0.1 0.019 14.9 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN91327.1 - 0.0095 14.8 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EDN91327.1 - 0.013 14.6 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EDN91327.1 - 0.02 13.5 0.4 0.029 13.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EDN91327.1 - 0.022 13.6 1.3 1.4 7.6 0.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.13 EDN91329.1 - 1.1e-26 93.2 0.5 2.1e-26 92.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91329.1 - 1e-06 28.5 11.8 2.1e-06 27.5 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EDN91329.1 - 0.0073 16.0 5.9 0.017 14.8 4.1 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Cep57_CLD_2 PF14197.1 EDN91329.1 - 0.013 15.4 1.0 0.03 14.2 0.7 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ADH_N PF08240.7 EDN91330.1 - 6.6e-25 86.9 0.7 1.3e-24 86.0 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN91330.1 - 2.1e-14 53.1 0.0 3.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EDN91330.1 - 0.00029 20.4 0.3 0.00029 20.4 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN91330.1 - 0.00097 18.3 0.1 0.0016 17.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDN91330.1 - 0.0041 16.7 0.2 0.0079 15.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Toprim_3 PF13362.1 EDN91330.1 - 0.052 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Toprim domain ThiF PF00899.16 EDN91330.1 - 0.055 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 EDN91330.1 - 0.079 12.8 0.4 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DUF3568 PF12092.3 EDN91332.1 - 0.0033 17.1 0.6 0.0057 16.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3568) DUF4480 PF13715.1 EDN91332.1 - 0.013 15.5 0.2 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) DUF222 PF02720.12 EDN91332.1 - 0.069 12.2 0.2 0.079 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF222) BNIP2 PF12496.3 EDN91332.1 - 0.16 12.1 6.1 0.5 10.5 3.7 1.9 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF1180 PF06679.7 EDN91332.1 - 0.19 11.5 5.2 0.32 10.8 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GFO_IDH_MocA PF01408.17 EDN91333.1 - 4.4e-10 40.1 0.3 1.9e-09 38.0 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 EDN91333.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.17 EDN91335.1 - 3e-35 121.2 0.0 3.5e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GSHPx PF00255.14 EDN91338.1 - 2.3e-41 139.5 0.0 2.8e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 EDN91338.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 EDN91338.1 - 0.0045 16.5 0.0 0.0074 15.8 0.0 1.4 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EDN91338.1 - 0.0049 16.5 0.0 0.007 16.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family DAO PF01266.19 EDN91339.1 - 2.6e-57 194.3 0.0 3.1e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN91339.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN91339.1 - 0.00033 21.0 0.1 0.0066 16.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN91339.1 - 0.00055 18.8 0.3 0.54 9.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EDN91339.1 - 0.0007 18.3 0.6 0.012 14.2 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EDN91339.1 - 0.0027 16.6 0.2 0.16 10.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDN91339.1 - 0.003 17.6 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN91339.1 - 0.0045 16.7 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN91339.1 - 0.0057 16.5 0.8 1.7 8.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN91339.1 - 0.13 11.3 0.0 7.4 5.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Acetyltransf_1 PF00583.19 EDN91342.1 - 2.7e-07 30.5 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN91342.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN91342.1 - 0.00042 20.1 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN91342.1 - 0.00056 20.0 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cellulase PF00150.13 EDN91343.1 - 2e-22 79.7 3.7 3.1e-22 79.1 2.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EDN91343.1 - 1.5e-10 40.5 15.6 5.7e-10 38.6 10.8 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 EDN91343.1 - 0.00044 19.2 0.1 0.003 16.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EDN91343.1 - 0.0042 17.5 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 EDN91343.1 - 0.019 13.9 0.1 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EDN91343.1 - 0.05 12.7 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase DUF1162 PF06650.7 EDN91344.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1162) RNase_H2-Ydr279 PF09468.5 EDN91345.1 - 0.013 14.7 0.3 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HC2 PF07382.6 EDN91346.1 - 0.17 11.7 22.6 0.3 10.9 15.7 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF3656 PF12392.3 EDN91346.1 - 0.24 11.4 4.2 2.1 8.4 2.1 2.1 2 0 0 2 2 2 0 Collagenase EF-hand_6 PF13405.1 EDN91347.1 - 0.008 15.9 0.1 0.062 13.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EDN91347.1 - 0.018 14.3 0.1 0.45 9.9 0.0 2.9 3 0 0 3 3 3 0 EF hand ACBP PF00887.14 EDN91347.1 - 0.023 14.3 0.0 1.6 8.4 0.0 2.4 1 1 1 2 2 2 0 Acyl CoA binding protein CENP-T PF15511.1 EDN91348.1 - 0.046 12.9 17.0 0.053 12.7 11.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Baculo_PP31 PF05311.6 EDN91349.1 - 0.049 12.9 0.9 0.057 12.6 0.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CsbD PF05532.7 EDN91351.1 - 0.3 10.7 5.7 0.47 10.1 3.9 1.3 1 0 0 1 1 1 0 CsbD-like FlgD PF03963.9 EDN91354.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region ORC6 PF05460.8 EDN91356.1 - 0.48 9.4 13.2 0.55 9.2 9.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Lipoprotein_X PF03305.8 EDN91356.1 - 0.67 9.2 6.9 0.95 8.7 4.8 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein FAM176 PF14851.1 EDN91356.1 - 3.6 7.2 12.3 7.6 6.1 8.5 1.5 1 1 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 EDN91356.1 - 3.7 7.3 12.0 4.6 7.0 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TSP9 PF11493.3 EDN91356.1 - 6.1 7.4 8.4 1.3 9.5 0.1 2.4 1 1 1 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Lin-8 PF03353.10 EDN91358.1 - 0.11 11.7 1.4 0.13 11.5 1.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PBP1_TM PF14812.1 EDN91358.1 - 0.37 11.1 8.3 0.7 10.2 5.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EBV-NA3 PF05009.7 EDN91358.1 - 1.8 7.7 4.2 2.3 7.3 2.9 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FAM176 PF14851.1 EDN91358.1 - 2.8 7.6 4.8 4.1 7.0 3.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2413 PF10310.4 EDN91358.1 - 4.1 6.1 7.8 4.9 5.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neisseria_TspB PF05616.8 EDN91358.1 - 4.9 5.4 6.2 5.4 5.2 4.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Fumble PF03630.9 EDN91360.1 - 0.018 13.8 1.3 0.031 13.1 0.9 1.4 1 0 0 1 1 1 0 Fumble DUF605 PF04652.11 EDN91360.1 - 0.25 10.7 33.9 0.3 10.4 23.5 1.0 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 EDN91360.1 - 0.51 8.4 45.8 0.62 8.1 31.7 1.0 1 0 0 1 1 1 0 Utp14 protein DUF883 PF05957.8 EDN91361.1 - 0.037 14.4 23.2 2.6 8.4 1.2 5.4 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF3659 PF12396.3 EDN91363.1 - 2.4e-182 590.8 104.7 5.4e-26 90.0 2.2 10.0 10 0 0 10 10 10 9 Protein of unknown function (DUF3659) DUF883 PF05957.8 EDN91363.1 - 0.98 9.8 8.9 61 4.1 2.3 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Abhydrolase_5 PF12695.2 EDN91364.1 - 9.9e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN91364.1 - 0.00019 21.1 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EDN91364.1 - 0.0007 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDN91364.1 - 0.0027 17.6 0.1 0.0061 16.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CLASP_N PF12348.3 EDN91364.1 - 0.021 14.1 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 CLASP N terminal Chlorosome_CsmC PF11098.3 EDN91367.1 - 0.12 12.0 12.5 0.15 11.7 8.7 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C DDE_1 PF03184.14 EDN91368.1 - 5.3e-19 68.2 0.0 5.8e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease LysM PF01476.15 EDN91369.1 - 9.9e-20 70.1 6.6 1e-05 25.3 0.1 4.5 4 0 0 4 4 4 4 LysM domain Sporozoite_P67 PF05642.6 EDN91369.1 - 1.3 6.7 6.3 1.9 6.2 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.23 EDN91370.1 - 2.6e-63 214.5 7.0 4.1e-63 213.8 4.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 EDN91370.1 - 4e-40 136.0 6.4 5.8e-13 49.0 0.2 5.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EDN91370.1 - 1.4e-36 122.4 11.0 1.2e-06 28.0 0.0 10.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EDN91370.1 - 1.4e-26 91.8 10.0 3.9e-09 36.4 0.3 8.5 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN91370.1 - 1e-24 86.3 10.7 4e-07 30.3 0.1 8.7 4 3 6 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN91370.1 - 9.2e-22 74.9 16.0 1.3e-05 24.9 0.0 9.9 11 0 0 11 11 11 5 Ankyrin repeat Chitin_bind_1 PF00187.14 EDN91370.1 - 7.4e-07 29.0 8.7 7.4e-07 29.0 6.0 5.3 6 0 0 6 6 6 1 Chitin recognition protein DUF1975 PF09318.5 EDN91372.1 - 0.021 14.4 1.0 0.021 14.4 0.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1975) DUF1977 PF09320.6 EDN91372.1 - 1.6 9.0 6.2 4.9 7.4 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1977) SGL PF08450.7 EDN91374.1 - 1.9e-70 237.0 0.4 2.2e-70 236.8 0.3 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EDN91374.1 - 0.00026 20.9 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EDN91374.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Strictosidine synthase Reg_prop PF07494.6 EDN91374.1 - 0.0072 16.2 0.8 0.79 9.9 0.0 3.3 3 0 0 3 3 3 1 Two component regulator propeller Lactonase PF10282.4 EDN91374.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller bZIP_2 PF07716.10 EDN91378.1 - 0.032 14.0 7.7 0.05 13.4 5.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF4140 PF13600.1 EDN91378.1 - 0.17 12.3 1.5 0.35 11.3 1.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.19 EDN91378.1 - 0.27 10.9 0.1 0.39 10.4 0.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TFIIA PF03153.8 EDN91378.1 - 9 6.0 13.0 0.42 10.4 4.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.17 EDN91379.1 - 4e-182 605.6 1.0 4.6e-182 605.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDN91379.1 - 0.0023 17.2 0.0 0.0087 15.3 0.0 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1487) SpoIIAA-like PF11964.3 EDN91379.1 - 0.08 13.2 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 SpoIIAA-like TAXi_C PF14541.1 EDN91379.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal HTH_psq PF05225.11 EDN91382.1 - 2e-12 46.4 0.0 3.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN91382.1 - 0.00034 20.3 0.0 0.00094 18.9 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Fungal_trans_2 PF11951.3 EDN91384.1 - 2.9e-41 141.3 11.1 1.4e-40 139.0 4.7 3.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91384.1 - 2.6e-07 30.4 6.9 6.5e-07 29.1 4.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 EDN91386.1 - 3.9e-57 192.9 8.9 4.5e-57 192.7 6.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EHN PF06441.7 EDN91386.1 - 0.25 11.2 2.7 0.22 11.4 0.6 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Flu_NP PF00506.13 EDN91386.1 - 0.27 9.6 2.4 4.5 5.6 0.3 2.4 2 1 1 3 3 3 0 Influenza virus nucleoprotein UreE_C PF05194.7 EDN91388.1 - 0.14 12.2 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain DUF3989 PF13150.1 EDN91390.1 - 0.15 11.4 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Fungal_trans PF04082.13 EDN91391.1 - 2.9e-26 91.9 0.1 4.5e-23 81.4 0.0 2.5 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91391.1 - 1.2e-09 37.8 8.3 2.3e-09 36.9 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.14 EDN91392.1 - 9e-76 254.7 0.0 1.4e-75 254.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 EDN91392.1 - 0.021 13.3 0.3 0.052 12.0 0.0 1.7 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Mito_carr PF00153.22 EDN91393.1 - 1.4e-43 146.5 10.2 6.4e-16 57.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_psq PF05225.11 EDN91396.1 - 4.7e-07 29.2 0.1 9.3e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDN91396.1 - 0.00023 20.4 0.0 0.00054 19.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease NADHdeh_related PF10125.4 EDN91396.1 - 0.0055 15.8 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase I, subunit N related protein DUF3038 PF11237.3 EDN91396.1 - 0.032 14.0 0.3 0.041 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) HTH_37 PF13744.1 EDN91396.1 - 0.27 11.0 1.6 1.8 8.4 1.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain zf-CCHC PF00098.18 EDN91397.1 - 0.0022 17.8 3.9 0.0041 16.9 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN91397.1 - 0.13 11.9 1.0 0.26 10.9 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Mito_carr PF00153.22 EDN91399.1 - 5.5e-67 221.5 4.0 5.3e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4200 PF13863.1 EDN91400.1 - 4.6 7.2 24.6 2.2 8.2 8.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FAD_binding_4 PF01565.18 EDN91402.1 - 4.2e-15 55.4 3.2 7.1e-15 54.7 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 EDN91402.1 - 7.1e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase BBE PF08031.7 EDN91402.1 - 0.0011 18.7 0.0 0.0033 17.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like AAA_29 PF13555.1 EDN91402.1 - 0.068 12.7 0.1 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 EDN91402.1 - 0.22 10.4 0.0 9.8 4.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein CENP-X PF09415.5 EDN91405.1 - 3.3e-24 84.4 0.0 6.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF4526 PF15029.1 EDN91405.1 - 2 7.8 8.3 3.3 7.1 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) Cu_bind_like PF02298.12 EDN91406.1 - 0.00066 19.4 0.4 0.004 16.9 0.3 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain DUF4551 PF15087.1 EDN91406.1 - 3.8 5.7 9.4 4.8 5.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.4 EDN91406.1 - 8.3 4.7 21.3 10 4.4 14.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TRAM_LAG1_CLN8 PF03798.11 EDN91407.1 - 3.4e-48 163.8 15.4 3.4e-48 163.8 10.7 1.9 2 0 0 2 2 2 1 TLC domain Cyd_oper_YbgE PF09600.5 EDN91407.1 - 0.015 15.4 1.8 0.015 15.4 1.3 2.5 2 1 1 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Abi PF02517.11 EDN91408.1 - 2.6 8.2 7.5 0.41 10.8 0.5 2.8 3 0 0 3 3 3 0 CAAX protease self-immunity HlyIII PF03006.15 EDN91410.1 - 6e-05 22.5 0.0 6.2e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related Fungal_trans PF04082.13 EDN91411.1 - 8.6e-17 60.8 0.1 1.6e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91411.1 - 1.5e-08 34.4 12.0 2.5e-08 33.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN91413.1 - 2.7e-28 98.5 1.0 4.2e-28 97.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91413.1 - 6.6e-08 32.3 13.9 1.2e-07 31.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.13 EDN91413.1 - 0.21 11.5 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Ribosomal_S19e PF01090.14 EDN91416.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e A_deaminase PF00962.17 EDN91417.1 - 2.1e-75 253.7 0.0 2.4e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase RHSP PF07999.6 EDN91418.1 - 0.18 10.3 1.0 0.23 10.0 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon hot spot protein RE_TdeIII PF09520.5 EDN91418.1 - 0.21 10.8 4.0 0.36 10.1 2.7 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DDE_1 PF03184.14 EDN91419.1 - 8.3e-27 93.7 1.0 6.6e-24 84.2 0.0 2.7 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 EDN91419.1 - 7.5e-11 41.4 1.0 1e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN91419.1 - 2.5e-07 30.4 0.2 1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN91419.1 - 0.015 15.1 6.7 0.031 14.1 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle SDA1 PF05285.7 EDN91421.1 - 0.0091 15.3 21.3 0.015 14.6 14.8 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 EDN91421.1 - 2.7 5.8 20.4 3.8 5.3 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Utp8 PF10395.4 EDN91422.1 - 6.3e-05 21.4 0.9 0.01 14.2 0.2 2.1 2 0 0 2 2 2 2 Utp8 family AAA PF00004.24 EDN91423.1 - 3.3e-06 27.3 0.0 7.5e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN91423.1 - 4e-06 25.8 2.0 0.00047 18.9 0.0 3.3 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EDN91423.1 - 0.00045 20.2 0.1 0.0036 17.3 0.0 2.6 3 1 1 4 4 4 1 AAA ATPase domain TIP49 PF06068.8 EDN91423.1 - 0.00082 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EDN91423.1 - 0.0028 18.4 0.0 0.014 16.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN91423.1 - 0.017 14.9 0.8 0.93 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EDN91423.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDN91423.1 - 0.029 14.0 0.1 0.5 10.0 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EDN91423.1 - 0.046 13.6 0.1 0.7 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EDN91423.1 - 0.048 12.5 0.1 0.16 10.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Ribosomal_S25 PF03297.10 EDN91424.1 - 6.7e-41 138.5 4.5 7.4e-41 138.4 3.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EDN91424.1 - 0.0015 17.8 0.2 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 EDN91424.1 - 0.0052 16.2 0.2 0.007 15.8 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 EDN91424.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.4 1 1 0 1 1 1 0 MarR family Cyt-b5 PF00173.23 EDN91425.1 - 1.9e-09 37.2 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.16 EDN91426.1 - 8.1e-12 44.9 10.3 8.1e-12 44.9 7.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDN91426.1 - 0.00039 20.1 10.0 0.00039 20.1 7.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DDE_1 PF03184.14 EDN91428.1 - 3.1e-06 26.4 0.1 1.9e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91428.1 - 0.012 15.3 0.1 0.036 13.8 0.0 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Phage_CI_repr PF07022.8 EDN91428.1 - 0.071 13.1 0.0 0.081 13.0 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Chitin_bind_1 PF00187.14 EDN91429.1 - 0.038 13.9 1.4 0.061 13.3 0.9 1.2 1 0 0 1 1 1 0 Chitin recognition protein zf-CCHC PF00098.18 EDN91429.1 - 0.039 13.9 3.6 0.067 13.1 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle IDO PF01231.13 EDN91430.1 - 8.2e-08 31.0 0.5 5.4e-07 28.3 0.1 2.2 2 1 0 2 2 2 1 Indoleamine 2,3-dioxygenase HJURP_C PF12347.3 EDN91430.1 - 0.048 13.2 0.6 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Methyltransf_26 PF13659.1 EDN91432.1 - 3.2e-06 27.1 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN91432.1 - 3.5e-06 26.6 0.0 5.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN91432.1 - 9.5e-05 21.8 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EDN91432.1 - 0.00012 22.4 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EDN91432.1 - 0.00017 20.9 0.0 0.00017 20.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EDN91432.1 - 0.00024 21.6 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN91432.1 - 0.00038 20.8 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN91432.1 - 0.00077 18.6 0.1 0.00089 18.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EDN91432.1 - 0.0014 17.6 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EDN91432.1 - 0.0016 18.1 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN91432.1 - 0.0029 17.9 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EDN91432.1 - 0.0058 15.6 0.0 0.0077 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FmrO PF07091.6 EDN91432.1 - 0.01 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EDN91432.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EDN91432.1 - 0.036 13.1 0.1 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.13 EDN91432.1 - 0.051 12.6 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EDN91432.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFS_1 PF07690.11 EDN91433.1 - 3.6e-14 52.2 13.8 4.4e-14 51.9 9.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3269 PF11673.3 EDN91434.1 - 0.11 12.8 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) GMC_oxred_N PF00732.14 EDN91437.1 - 1.8e-79 266.9 0.0 2.4e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN91437.1 - 1.3e-35 122.8 0.4 4.3e-35 121.1 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EDN91437.1 - 8.1e-08 31.5 0.7 1.5e-06 27.4 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN91437.1 - 4.4e-05 22.5 0.1 0.026 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EDN91437.1 - 0.00072 18.5 0.1 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EDN91437.1 - 0.02 13.9 0.1 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 EDN91437.1 - 0.12 12.4 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 EDN91437.1 - 0.15 12.1 0.1 0.43 10.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TPR_12 PF13424.1 EDN91439.1 - 1.5e-24 85.7 8.3 5.8e-08 32.5 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EDN91439.1 - 3e-12 46.0 18.0 1.1e-05 25.2 0.4 5.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN91439.1 - 3.4e-06 27.5 4.2 0.11 13.2 1.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDN91439.1 - 7.3e-05 22.3 2.2 0.57 9.8 0.0 3.9 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.1 EDN91439.1 - 8.2e-05 22.8 0.3 1.5 9.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN91439.1 - 0.00022 20.8 3.8 1.7 8.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN91439.1 - 0.00058 20.0 5.5 0.28 11.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN91439.1 - 0.0089 15.7 2.3 28 4.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN91439.1 - 0.018 15.1 0.8 0.31 11.1 0.0 3.2 3 3 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDN91439.1 - 0.047 14.1 0.2 24 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN91439.1 - 0.077 13.6 4.9 9.2 7.2 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDN91439.1 - 0.12 12.2 0.6 2.1 8.3 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 EDN91441.1 - 3.6e-06 27.1 0.1 2.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EDN91441.1 - 5.6e-05 22.9 0.2 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase DUF463 PF04317.7 EDN91441.1 - 0.025 13.1 0.2 0.098 11.2 0.0 1.8 2 0 0 2 2 2 0 YcjX-like family, DUF463 TrwB_AAD_bind PF10412.4 EDN91441.1 - 0.032 12.8 0.2 0.097 11.2 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Topo-VIb_trans PF09239.6 EDN91441.1 - 0.042 13.3 0.2 0.064 12.7 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer UPF0261 PF06792.6 EDN91441.1 - 0.048 12.1 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) ATG_C PF09333.6 EDN91441.1 - 0.055 13.6 0.1 0.088 12.9 0.0 1.2 1 0 0 1 1 1 0 ATG C terminal domain Miro PF08477.8 EDN91441.1 - 0.11 12.9 0.1 0.94 9.9 0.0 2.4 3 1 1 4 4 4 0 Miro-like protein MobB PF03205.9 EDN91441.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDN91441.1 - 0.21 12.3 0.9 2.2 9.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain ClpB_D2-small PF10431.4 EDN91441.1 - 0.41 10.5 2.3 2.2 8.2 1.6 2.0 1 1 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SDA1 PF05285.7 EDN91442.1 - 1.3e-80 271.0 31.1 1.3e-80 271.0 21.6 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EDN91442.1 - 7.3e-22 77.4 0.3 2.9e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Ribosomal_S7 PF00177.16 EDN91443.1 - 3e-40 137.2 1.8 3.7e-40 136.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Methyltransf_11 PF08241.7 EDN91448.1 - 1.4e-06 28.7 0.0 9.3e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN91448.1 - 0.00021 21.8 0.0 0.93 10.0 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_8 PF05148.10 EDN91448.1 - 0.0049 16.5 0.0 0.034 13.7 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.7 EDN91448.1 - 0.009 16.4 0.0 0.15 12.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN91448.1 - 0.029 13.9 0.0 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 EDN91451.1 - 9.1e-11 41.9 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN91451.1 - 2.5e-10 40.9 0.0 3.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UbiA PF01040.13 EDN91453.1 - 3.2e-07 29.8 0.6 3.9e-07 29.5 0.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF754 PF05449.6 EDN91453.1 - 0.024 14.6 0.3 0.024 14.6 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF754) Flavi_NS2A PF01005.14 EDN91453.1 - 0.051 12.8 0.2 0.081 12.1 0.2 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A IDO PF01231.13 EDN91455.1 - 3.3e-44 150.9 0.0 4.6e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pyr_redox_2 PF07992.9 EDN91457.1 - 6e-27 94.8 0.0 1.9e-26 93.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN91457.1 - 2.3e-17 63.1 5.1 4.5e-15 55.8 0.9 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EDN91457.1 - 3e-13 49.1 0.0 6.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EDN91457.1 - 2e-10 41.1 0.0 7e-05 22.9 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EDN91457.1 - 2.1e-05 24.7 0.0 5.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_7 PF13241.1 EDN91457.1 - 0.00027 21.1 0.6 0.044 14.0 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 EDN91457.1 - 0.00051 19.0 5.5 0.0026 16.7 0.0 3.2 2 2 3 5 5 5 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EDN91457.1 - 0.00065 18.7 0.1 0.92 8.3 0.0 3.0 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 EDN91457.1 - 0.0078 15.3 0.2 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) Malic_M PF03949.10 EDN91457.1 - 0.012 15.1 0.1 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.1 EDN91457.1 - 0.027 14.2 1.0 7.2 6.3 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EDN91457.1 - 0.084 11.4 1.9 0.34 9.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Arginase PF00491.16 EDN91458.1 - 7.9e-50 169.6 0.0 9.3e-43 146.5 0.0 2.0 2 0 0 2 2 2 2 Arginase family Peptidase_C2 PF00648.16 EDN91459.1 - 7.5e-58 195.8 0.4 3.3e-39 134.6 0.2 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease Mt_ATP-synt_B PF05405.9 EDN91459.1 - 4.9 6.5 14.7 10 5.5 10.2 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease PF00324.16 EDN91461.1 - 1.2e-123 413.0 38.8 1.5e-123 412.6 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN91461.1 - 2.1e-34 118.7 40.8 2.9e-34 118.3 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 EDN91461.1 - 1.3 8.8 6.5 1.7 8.4 2.2 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Smr PF01713.16 EDN91462.1 - 0.01 16.0 0.1 0.036 14.2 0.1 2.0 1 1 0 1 1 1 0 Smr domain TPR_MLP1_2 PF07926.7 EDN91462.1 - 0.013 15.2 2.9 0.013 15.2 2.0 3.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EDN91462.1 - 2.2 8.1 25.5 1.4 8.8 8.2 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding HAP1_N PF04849.8 EDN91462.1 - 2.8 6.7 27.7 1.7 7.4 14.5 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Amino_oxidase PF01593.19 EDN91463.1 - 8.9e-42 143.6 0.1 3.8e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDN91463.1 - 2.1e-15 56.4 0.0 3.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDN91463.1 - 8.8e-08 32.4 0.1 2.3e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN91463.1 - 1.2e-07 31.6 0.1 0.011 15.5 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EDN91463.1 - 6.4e-06 25.3 0.9 7.4e-05 21.8 0.3 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN91463.1 - 9e-06 26.0 0.5 5.6e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN91463.1 - 0.00034 20.5 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN91463.1 - 0.00066 18.2 0.0 0.016 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EDN91463.1 - 0.0011 18.0 0.2 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDN91463.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EDN91463.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EDN91463.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EDN91463.1 - 0.082 12.5 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EDN91463.1 - 0.14 11.0 0.1 4.3 6.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HhH-GPD PF00730.20 EDN91464.1 - 1.9e-18 66.7 0.0 3.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDN91464.1 - 2.7e-08 33.0 0.0 9.1e-08 31.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif DSBA PF01323.15 EDN91468.1 - 1.1e-24 87.0 0.1 1.3e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HHH_5 PF14520.1 EDN91468.1 - 0.0038 17.3 0.2 0.91 9.7 0.0 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain Thioredoxin_4 PF13462.1 EDN91468.1 - 0.016 15.2 0.1 0.044 13.7 0.0 1.6 1 1 0 2 2 2 0 Thioredoxin Pkinase PF00069.20 EDN91471.1 - 7.5e-57 192.4 0.0 1.3e-56 191.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91471.1 - 7.3e-20 71.1 0.3 2.1e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDN91471.1 - 0.067 12.9 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN91471.1 - 0.13 11.7 0.5 0.28 10.7 0.3 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 EDN91473.1 - 4.2e-100 335.0 4.8 5.1e-100 334.7 3.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EDN91473.1 - 0.033 12.3 2.2 0.18 9.9 0.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Clusterin PF01093.12 EDN91473.1 - 0.056 12.2 0.2 0.27 9.9 0.0 1.8 2 0 0 2 2 2 0 Clusterin Tweety PF04906.8 EDN91473.1 - 0.19 10.1 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 Tweety DUF3292 PF11696.3 EDN91473.1 - 0.27 9.0 10.1 0.055 11.3 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) DUF4395 PF14340.1 EDN91473.1 - 1.6 8.7 7.8 1.6 8.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) COesterase PF00135.23 EDN91474.1 - 3.2e-96 323.1 0.0 4.2e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN91474.1 - 0.00044 19.8 0.7 0.13 11.7 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN91474.1 - 0.012 14.8 0.5 0.02 14.1 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Acyl-CoA_dh_1 PF00441.19 EDN91475.1 - 2.1e-31 109.0 0.6 3.5e-31 108.3 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EDN91475.1 - 9.9e-21 73.3 0.0 2.4e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EDN91475.1 - 9.2e-17 60.2 0.5 2e-16 59.2 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN91475.1 - 3.6e-09 37.1 0.1 7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN91475.1 - 2.9e-05 24.3 0.0 6.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RE_LlaJI PF09563.5 EDN91475.1 - 0.035 12.7 0.0 0.061 12.0 0.0 1.4 1 0 0 1 1 1 0 LlaJI restriction endonuclease A_deaminase PF00962.17 EDN91476.1 - 1.5e-46 158.8 0.0 6.7e-45 153.4 0.0 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase ATG2_CAD PF13329.1 EDN91477.1 - 2.2e-46 157.2 0.1 4.9e-46 156.1 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EDN91477.1 - 1.3e-24 86.2 0.1 3.2e-24 84.9 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EDN91477.1 - 0.0085 15.6 1.3 0.11 12.0 0.1 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ubiquitin PF00240.18 EDN91478.1 - 8.3e-12 44.3 0.0 2.3e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN91478.1 - 3.4e-10 39.4 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 EDN91478.1 - 5.6e-08 32.5 15.4 9.1e-08 31.8 10.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Telomere_Sde2 PF13019.1 EDN91478.1 - 0.00045 19.9 0.4 0.00072 19.2 0.3 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 EDN91478.1 - 0.00045 20.3 0.0 0.00057 20.0 0.0 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ADH_N PF08240.7 EDN91481.1 - 8.5e-23 80.2 2.1 1.3e-22 79.5 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN91481.1 - 3.1e-18 65.5 0.0 4.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN91481.1 - 0.00022 22.0 0.0 0.00033 21.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN91481.1 - 0.0099 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDN91481.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNA_pol_Rpb2_6 PF00562.23 EDN91482.1 - 2.4e-120 401.8 0.3 1.5e-119 399.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDN91482.1 - 4.3e-64 215.1 0.0 6.9e-64 214.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDN91482.1 - 2.5e-48 164.0 0.2 4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDN91482.1 - 2.6e-29 101.3 0.0 6.4e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDN91482.1 - 3.7e-23 81.0 0.3 9.9e-23 79.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDN91482.1 - 4.3e-23 80.8 0.0 1e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDN91482.1 - 3.4e-22 78.1 0.1 6.8e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 V-ATPase_G PF03179.10 EDN91484.1 - 3.8e-29 101.0 16.7 4.3e-29 100.9 11.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Nop25 PF09805.4 EDN91484.1 - 0.01 15.9 14.7 0.012 15.6 10.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) MMR_HSR1_C PF08438.5 EDN91484.1 - 0.021 15.0 3.3 0.034 14.3 2.3 1.3 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Striatin PF08232.7 EDN91484.1 - 0.043 14.1 9.2 0.05 13.9 6.4 1.0 1 0 0 1 1 1 0 Striatin family RRF PF01765.14 EDN91484.1 - 0.2 11.1 13.9 0.27 10.7 9.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HypD PF01924.11 EDN91484.1 - 0.24 10.0 1.9 0.28 9.8 1.3 1.0 1 0 0 1 1 1 0 Hydrogenase formation hypA family Vfa1 PF08432.5 EDN91484.1 - 0.35 10.8 15.4 0.4 10.6 10.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3539 PF12058.3 EDN91484.1 - 0.36 10.6 2.8 11 5.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3539) DUF2201_N PF13203.1 EDN91484.1 - 0.59 9.2 4.6 0.67 9.0 3.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Z1 PF10593.4 EDN91484.1 - 0.59 9.3 3.8 0.67 9.1 2.6 1.1 1 0 0 1 1 1 0 Z1 domain Med8 PF10232.4 EDN91484.1 - 0.67 9.4 4.8 0.73 9.2 3.3 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 14-3-3 PF00244.15 EDN91484.1 - 0.71 8.9 8.6 0.25 10.3 2.5 1.9 1 1 1 2 2 2 0 14-3-3 protein DUF87 PF01935.12 EDN91484.1 - 0.79 9.4 3.8 0.95 9.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 SAPS PF04499.10 EDN91484.1 - 1.2 7.6 7.6 1.2 7.6 5.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DRY_EERY PF09750.4 EDN91484.1 - 1.6 8.8 8.0 2 8.5 5.6 1.1 1 0 0 1 1 1 0 Alternative splicing regulator Borrelia_P83 PF05262.6 EDN91484.1 - 1.7 6.8 16.9 1.9 6.6 11.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 EDN91484.1 - 2.3 7.5 14.0 2.7 7.2 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3987 PF13148.1 EDN91484.1 - 2.5 6.5 10.7 2.7 6.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2317 PF10079.4 EDN91484.1 - 2.7 6.5 8.4 3.2 6.2 5.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Atg14 PF10186.4 EDN91484.1 - 3.1 6.6 10.4 3.6 6.4 7.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_B PF00430.13 EDN91484.1 - 4.3 7.1 17.8 25 4.6 12.4 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) U79_P34 PF03064.11 EDN91484.1 - 4.3 6.7 12.7 5 6.5 8.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 OmpH PF03938.9 EDN91484.1 - 4.3 7.2 13.1 5.3 6.9 9.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Arc_PepC_II PF06847.6 EDN91484.1 - 4.9 7.6 9.2 0.7 10.3 1.9 2.0 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II NPR3 PF03666.8 EDN91484.1 - 5.1 5.5 6.4 5.4 5.4 4.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 EDN91484.1 - 5.2 6.8 11.8 6 6.6 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EDN91484.1 - 5.9 4.4 10.3 6.5 4.3 7.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EDN91484.1 - 9.1 5.1 9.6 11 4.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF676 PF05057.9 EDN91485.1 - 8.2e-07 28.5 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EDN91485.1 - 1.2e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDN91485.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN91485.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EDN91485.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EDN91485.1 - 0.0043 16.0 0.0 0.0051 15.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EDN91485.1 - 0.028 13.5 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EDN91485.1 - 0.041 13.1 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) DUF159 PF02586.9 EDN91486.1 - 6.1e-56 189.2 1.3 7.9e-56 188.8 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 Transp_cyt_pur PF02133.10 EDN91487.1 - 3.1e-151 503.8 44.4 3.6e-151 503.6 30.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cellulase PF00150.13 EDN91488.1 - 8.4e-52 176.1 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EDN91488.1 - 4.5e-10 39.0 14.3 1.5e-09 37.3 9.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_6 PF01341.12 EDN91489.1 - 2.5e-90 302.9 5.5 1.2e-57 195.6 2.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EDN91489.1 - 3.4e-11 42.5 15.2 3.4e-11 42.5 10.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_transf_8 PF01501.15 EDN91491.1 - 1.3e-27 96.7 0.0 1.5e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 EDN91492.1 - 5.1e-34 115.8 0.4 7.1e-13 48.0 0.0 3.2 1 1 2 3 3 3 3 Mitochondrial carrier protein Nucleopor_Nup85 PF07575.8 EDN91493.1 - 1.9e-11 42.9 1.2 5.3e-06 24.9 0.0 3.2 3 1 0 3 3 3 2 Nup85 Nucleoporin Tubulin PF00091.20 EDN91494.1 - 2.9e-64 216.8 0.0 4.5e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN91494.1 - 3.8e-46 156.2 0.6 6.4e-46 155.4 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN91494.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain WD40 PF00400.27 EDN91497.1 - 2e-59 195.4 26.0 4.1e-11 42.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDN91497.1 - 0.00021 19.6 4.0 0.28 9.2 0.1 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EDN91497.1 - 0.011 14.0 0.0 2.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TAF8_C PF10406.4 EDN91498.1 - 6e-21 74.2 0.1 1.9e-20 72.6 0.1 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EDN91498.1 - 7.3e-08 32.0 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Competence PF03772.11 EDN91499.1 - 0.14 11.1 0.2 0.15 11.1 0.2 1.0 1 0 0 1 1 1 0 Competence protein YwhD PF08741.5 EDN91500.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 YwhD family Mitochondr_Som1 PF11093.3 EDN91501.1 - 3.9e-14 52.1 0.0 4.6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 2OG-FeII_Oxy_2 PF13532.1 EDN91502.1 - 3.6e-28 98.7 0.0 7.3e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EDN91502.1 - 1.4e-27 96.7 0.0 3e-27 95.6 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family GST_C PF00043.20 EDN91502.1 - 0.0022 17.9 0.0 0.0073 16.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN91502.1 - 0.0029 18.0 0.1 0.013 15.9 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PEHE PF15275.1 EDN91502.1 - 1.3 9.4 12.4 0.14 12.5 3.2 2.9 2 1 1 3 3 3 0 PEHE domain ECH PF00378.15 EDN91505.1 - 1.6e-39 135.5 0.0 4.9e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EDN91505.1 - 0.0028 17.7 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region zf-CCHC PF00098.18 EDN91506.1 - 1.9e-48 160.1 90.7 3.3e-06 26.7 2.1 11.2 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_4 PF14392.1 EDN91506.1 - 2.9e-06 26.8 80.1 0.024 14.2 0.5 11.2 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.1 EDN91506.1 - 9.9e-05 22.0 78.6 0.08 12.6 0.3 11.0 2 2 8 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 EDN91506.1 - 0.00018 20.9 0.5 0.00018 20.9 0.3 9.3 6 3 5 11 11 11 3 Zinc knuckle Aldo_ket_red PF00248.16 EDN91507.1 - 1.5e-66 224.1 0.0 1.7e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RFC1 PF08519.7 EDN91508.1 - 5.8e-59 198.2 0.2 2e-58 196.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EDN91508.1 - 2.8e-12 46.6 0.0 9e-12 44.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EDN91508.1 - 1.4e-09 38.2 0.0 3.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN91508.1 - 9.4e-06 24.5 0.1 2.3e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDN91508.1 - 5.7e-05 23.9 0.0 5.7e-05 23.9 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_22 PF13401.1 EDN91508.1 - 0.00014 21.9 0.0 0.0011 19.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN91508.1 - 0.00066 19.3 0.2 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDN91508.1 - 0.0028 17.6 1.1 0.014 15.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EDN91508.1 - 0.0079 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN91508.1 - 0.008 16.4 0.1 0.008 16.4 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EDN91508.1 - 0.022 14.6 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDN91508.1 - 0.039 12.9 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EDN91508.1 - 0.057 13.0 0.1 0.32 10.6 0.0 2.1 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EDN91508.1 - 0.061 13.5 0.1 0.47 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EDN91508.1 - 0.085 12.8 0.0 0.085 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF1126 PF06565.7 EDN91508.1 - 0.13 11.7 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) Ribosomal_L16 PF00252.13 EDN91509.1 - 1.3e-28 99.3 0.2 1.7e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Tbf5 PF06331.7 EDN91510.1 - 4e-27 93.7 0.6 4.3e-27 93.6 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 PROCN PF08083.6 EDN91512.1 - 0.18 10.2 0.5 0.18 10.2 0.4 1.0 1 0 0 1 1 1 0 PROCN (NUC071) domain RVT_1 PF00078.22 EDN91513.1 - 1.3e-36 125.9 0.0 3.2e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN91513.1 - 1.4e-14 53.7 0.1 3.7e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN91513.1 - 6.3e-10 39.4 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN91513.1 - 2.8e-05 24.1 0.2 7.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EDN91516.1 - 1.7e-40 138.8 53.5 1.7e-40 138.8 37.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily SKN1 PF03935.10 EDN91520.1 - 2.5e-233 774.7 5.6 3.4e-233 774.3 3.9 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Ribosomal_L3 PF00297.17 EDN91522.1 - 2.3e-119 397.5 7.1 2.8e-119 397.3 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.6 EDN91523.1 - 0.048 13.5 0.2 11 5.9 0.0 2.3 1 1 0 2 2 2 0 Nuclease A inhibitor-like protein ARGLU PF15346.1 EDN91524.1 - 2 8.1 15.9 2.6 7.8 11.0 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CAF-1_p150 PF11600.3 EDN91524.1 - 7 5.9 24.7 10 5.4 17.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sugar_tr PF00083.19 EDN91525.1 - 4.1e-85 286.0 18.8 7.5e-62 209.3 1.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN91525.1 - 5.1e-20 71.5 37.3 1.7e-16 59.9 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 EDN91525.1 - 0.38 10.4 2.8 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Alpha-L-AF_C PF06964.7 EDN91526.1 - 1.9e-36 125.5 0.0 3.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Retrotrans_gag PF03732.12 EDN91528.1 - 1.1e-10 41.4 0.4 2.1e-10 40.5 0.3 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EDN91528.1 - 5.2e-09 35.8 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN91528.1 - 2.1e-07 31.3 0.0 4.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EDN91528.1 - 8.8e-07 28.5 1.1 1.8e-06 27.5 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.5 EDN91528.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.1 EDN91528.1 - 0.036 13.5 0.1 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EDN91528.1 - 0.055 13.2 0.9 0.1 12.3 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN91528.1 - 0.21 11.2 1.1 0.41 10.3 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EDN91529.1 - 1e-20 74.0 0.0 1.4e-19 70.3 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EDN91529.1 - 5.7e-13 48.3 4.1 1.3e-12 47.1 2.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SHS2_Rpb7-N PF03876.12 EDN91531.1 - 2.8e-06 27.3 0.0 7.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3807 PF12720.2 EDN91531.1 - 0.081 13.0 14.0 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Zip PF02535.17 EDN91531.1 - 2 7.3 4.2 2.7 6.9 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TetR_C_3 PF08362.6 EDN91533.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region BCA_ABC_TP_C PF12399.3 EDN91533.1 - 0.42 10.3 2.9 0.62 9.8 0.0 2.7 4 0 0 4 4 4 0 Branched-chain amino acid ATP-binding cassette transporter Aminotran_5 PF00266.14 EDN91535.1 - 1e-96 323.9 0.0 1.3e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDN91535.1 - 8.5e-08 31.6 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDN91535.1 - 0.00028 20.0 0.1 0.00076 18.6 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EDN91535.1 - 0.095 10.9 0.1 0.28 9.4 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.13 EDN91536.1 - 1.2e-63 214.7 8.6 1.5e-63 214.3 5.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EDN91536.1 - 2.1e-13 49.4 0.1 4.1e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN91536.1 - 4.6e-13 48.5 0.0 8.4e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN91536.1 - 4.7e-10 38.8 1.1 1.2e-09 37.5 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain Vps5 PF09325.5 EDN91536.1 - 0.01 15.1 7.2 0.42 9.8 1.8 2.3 2 0 0 2 2 2 0 Vps5 C terminal like YlqD PF11068.3 EDN91536.1 - 6.9 6.7 8.9 4.7 7.2 0.1 2.5 3 0 0 3 3 3 0 YlqD protein Exo_endo_phos_2 PF14529.1 EDN91540.1 - 1.8e-15 56.6 0.1 3.1e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN91540.1 - 7.2e-07 29.3 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EDN91541.1 - 4.3e-26 91.5 0.0 6.8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN91541.1 - 5.8e-10 39.6 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 RNase H F-box PF00646.28 EDN91542.1 - 0.00022 20.7 0.1 0.00079 19.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN91542.1 - 0.0081 15.8 0.1 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EDN91543.1 - 3.3e-39 134.5 28.8 2.8e-31 108.5 4.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN91543.1 - 0.0006 18.3 3.5 0.0006 18.3 2.4 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein OATP PF03137.15 EDN91543.1 - 0.00085 17.4 0.6 0.15 10.1 0.0 2.4 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Mem_trans PF03547.13 EDN91543.1 - 0.0045 15.3 0.0 0.009 14.3 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein BSP_II PF05432.6 EDN91543.1 - 0.01 15.1 2.4 0.015 14.5 1.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BT1 PF03092.11 EDN91543.1 - 0.019 13.6 0.9 0.079 11.6 0.4 1.9 1 1 1 2 2 2 0 BT1 family PUCC PF03209.10 EDN91543.1 - 0.067 11.8 8.9 0.14 10.8 1.2 2.6 2 0 0 2 2 2 0 PUCC protein CTNNBL PF08216.6 EDN91544.1 - 3.1e-36 123.2 0.2 1.8e-35 120.8 0.0 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EDN91544.1 - 0.013 15.3 0.3 1.2 9.0 0.0 3.4 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat Methyltransf_16 PF10294.4 EDN91547.1 - 1.3e-17 63.7 0.0 2.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EDN91547.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN91547.1 - 4.4e-06 26.1 0.0 7.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EDN91547.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EDN91547.1 - 3.8e-05 23.3 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN91547.1 - 0.00042 19.5 0.0 0.00067 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDN91547.1 - 0.00047 20.1 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN91547.1 - 0.002 18.5 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN91547.1 - 0.0031 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN91547.1 - 0.004 17.4 0.0 0.0081 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN91547.1 - 0.0056 17.1 0.1 0.017 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 EDN91547.1 - 0.061 12.8 0.0 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Ribosomal_S24e PF01282.14 EDN91548.1 - 3.4e-34 116.4 0.0 5.4e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EDN91548.1 - 0.034 13.5 1.4 0.038 13.3 1.0 1.2 1 0 0 1 1 1 0 RRXRR protein PKI PF02827.11 EDN91548.1 - 0.1 12.6 1.2 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Sulfate_tra_GLY PF13792.1 EDN91551.1 - 0.0064 16.1 1.3 0.0096 15.5 0.9 1.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif YoqO PF14037.1 EDN91551.1 - 0.02 14.9 0.3 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 YoqO-like protein DUF1361 PF07099.6 EDN91551.1 - 0.056 13.2 0.1 0.061 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) Pro_isomerase PF00160.16 EDN91553.1 - 5.9e-35 120.7 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EDN91553.1 - 8.8e-12 44.4 0.1 1.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN91553.1 - 3e-09 36.5 0.1 8.3e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN91553.1 - 5e-08 32.8 0.0 1.4e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN91553.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arrestin_N PF00339.24 EDN91554.1 - 9.7e-16 57.9 0.0 6.3e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.11 EDN91555.1 - 8.1e-27 93.8 35.8 7.2e-15 54.5 13.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN91555.1 - 5.2e-18 64.8 13.0 1.4e-17 63.4 8.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter HTH_psq PF05225.11 EDN91556.1 - 1e-11 44.1 0.0 1.2e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_37 PF13744.1 EDN91556.1 - 0.0021 17.8 0.3 0.0024 17.6 0.2 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain NUMOD1 PF07453.8 EDN91556.1 - 0.0035 17.1 0.1 0.0063 16.3 0.1 1.5 1 1 0 1 1 1 1 NUMOD1 domain HTH_24 PF13412.1 EDN91556.1 - 0.005 16.2 0.5 0.0063 15.8 0.4 1.3 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EDN91556.1 - 0.0093 15.5 0.1 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EDN91556.1 - 0.015 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_1 PF03184.14 EDN91557.1 - 1.2e-23 83.4 0.3 3.3e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91557.1 - 0.025 14.3 0.6 0.18 11.6 0.0 2.5 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF904 PF06005.7 EDN91558.1 - 0.066 13.5 0.3 0.089 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Glyco_tran_WecB PF03808.8 EDN91558.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family SAM_2 PF07647.12 EDN91559.1 - 2.5e-13 49.6 0.0 4.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EDN91559.1 - 6.1e-09 36.0 0.0 1.5e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EDN91559.1 - 5e-07 29.9 0.2 4.6e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain SAM_1 PF00536.25 EDN91559.1 - 0.0029 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EDN91559.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.15 EDN91560.1 - 1.5e-10 40.3 0.3 2.9e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EDN91560.1 - 0.008 15.6 0.2 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit LisH PF08513.6 EDN91563.1 - 0.048 13.4 0.2 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 LisH zf-CCHC PF00098.18 EDN91564.1 - 1.9e-34 115.9 52.2 2.9e-07 30.0 0.5 6.8 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 EDN91564.1 - 7.8e-11 41.4 38.2 0.03 13.9 0.3 7.1 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.1 EDN91564.1 - 0.00014 21.5 29.1 0.36 10.5 0.1 6.2 5 1 1 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EDN91564.1 - 0.033 13.8 1.7 0.033 13.8 1.2 6.5 6 1 1 7 7 7 0 Zinc knuckle Peptidase_C42 PF05533.7 EDN91564.1 - 0.063 13.1 1.4 0.1 12.4 0.4 1.7 1 1 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 WD40 PF00400.27 EDN91566.1 - 2.2e-56 185.8 4.7 8.5e-10 38.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN91566.1 - 0.00046 19.0 0.0 0.026 13.2 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 EDN91567.1 - 7.6e-38 129.4 0.0 9.2e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component UPF1_Zn_bind PF09416.5 EDN91568.1 - 3.8e-70 234.3 2.0 3.8e-70 234.3 1.4 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EDN91568.1 - 2.5e-57 194.1 1.7 3.8e-57 193.5 1.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EDN91568.1 - 4.2e-43 147.0 0.0 8.3e-40 136.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EDN91568.1 - 1.4e-14 53.6 1.1 4.2e-14 52.0 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDN91568.1 - 4.2e-12 46.0 0.2 8.3e-11 41.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDN91568.1 - 4.1e-09 36.5 0.0 7.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EDN91568.1 - 1.4e-05 24.7 0.1 0.25 10.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EDN91568.1 - 0.00024 20.5 0.0 0.0076 15.5 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EDN91568.1 - 0.00056 18.9 0.3 0.004 16.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EDN91568.1 - 0.00066 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EDN91568.1 - 0.0036 16.3 0.3 0.68 8.8 0.0 2.2 1 1 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 EDN91568.1 - 0.0061 16.0 0.1 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EDN91568.1 - 0.0064 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN91568.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDN91568.1 - 0.027 13.5 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EDN91568.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EDN91568.1 - 0.067 13.3 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Ribosomal_S13_N PF08069.7 EDN91568.1 - 0.093 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.11 EDN91568.1 - 0.099 11.8 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EDN91568.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EDN91568.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Brix PF04427.13 EDN91569.1 - 1.8e-45 154.9 0.9 2.4e-45 154.5 0.6 1.2 1 0 0 1 1 1 1 Brix domain Cu-oxidase_3 PF07732.10 EDN91571.1 - 5.4e-46 155.1 3.9 7.6e-45 151.4 0.5 3.0 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN91571.1 - 1.4e-40 138.0 7.1 3.8e-39 133.3 0.5 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EDN91571.1 - 1.8e-37 128.7 0.2 8.8e-36 123.2 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase SNARE PF05739.14 EDN91572.1 - 1.5e-14 53.3 2.2 6.6e-14 51.3 1.5 2.2 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EDN91572.1 - 1.2e-10 41.4 7.9 1.2e-10 41.4 5.5 2.1 2 1 0 2 2 2 1 Syntaxin DUF883 PF05957.8 EDN91572.1 - 0.59 10.5 8.1 5.7 7.4 0.6 3.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) FadA PF09403.5 EDN91572.1 - 2.3 8.2 8.6 0.5 10.3 0.0 2.4 2 1 0 2 2 2 0 Adhesion protein FadA COPIIcoated_ERV PF07970.7 EDN91573.1 - 3.3e-35 121.7 0.0 4.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDN91573.1 - 1.5e-20 73.0 0.0 2.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1996 PF09362.5 EDN91575.1 - 1.5e-87 293.2 1.0 1.5e-87 293.2 0.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WSC PF01822.14 EDN91575.1 - 3.9e-20 71.5 4.7 3.9e-20 71.5 3.3 2.6 3 0 0 3 3 3 1 WSC domain DHDPS PF00701.17 EDN91577.1 - 7.8e-33 113.2 0.0 1e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.9 EDN91578.1 - 1.3e-21 77.3 0.0 1.8e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase DUF3222 PF11519.3 EDN91578.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Hydrolase_like PF13242.1 EDN91580.1 - 1.2e-11 44.1 0.0 3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EDN91580.1 - 6.6e-07 29.1 0.2 3.4e-05 23.6 0.0 2.5 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDN91580.1 - 0.12 12.6 0.0 9.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 EDN91581.1 - 1.7e-09 37.3 0.0 0.00078 18.6 0.0 2.0 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN91582.1 - 1.5e-13 51.2 0.0 2.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Sugar_tr PF00083.19 EDN91583.1 - 3.7e-62 210.3 22.9 1.2e-61 208.6 15.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN91583.1 - 4.3e-15 55.2 44.0 2.4e-11 42.9 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_PH PF01138.16 EDN91584.1 - 1.3e-14 54.6 0.0 3.1e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDN91584.1 - 0.017 15.0 0.1 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.16 EDN91586.1 - 5.8e-10 39.8 0.0 8.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDN91586.1 - 1.3e-08 34.8 2.2 8.5e-08 32.2 1.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EDN91586.1 - 9.1e-05 21.9 0.3 0.00074 18.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Chorismate_bind PF00425.13 EDN91587.1 - 8.8e-82 274.2 0.0 2.5e-80 269.5 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 EDN91587.1 - 4.4e-32 111.0 0.0 1.3e-27 96.5 0.0 3.3 3 0 0 3 3 3 3 Anthranilate synthase component I, N terminal region Antigen_Bd37 PF11641.3 EDN91588.1 - 0.16 11.2 2.9 0.13 11.4 0.3 1.8 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Caps_synth_GfcC PF06251.6 EDN91588.1 - 0.35 9.9 2.6 0.2 10.8 0.4 1.5 2 0 0 2 2 2 0 Capsule biosynthesis GfcC 3Beta_HSD PF01073.14 EDN91590.1 - 3.9e-32 111.0 0.0 4.9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN91590.1 - 1.3e-13 50.9 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN91590.1 - 0.00032 19.7 0.0 0.00043 19.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EDN91590.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Rad51 PF08423.6 EDN91591.1 - 4.5e-117 389.4 0.1 5.7e-117 389.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EDN91591.1 - 1.8e-12 46.9 0.1 2.3e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EDN91591.1 - 5.6e-10 38.9 0.0 8.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EDN91591.1 - 1.2e-08 34.3 0.0 2.2e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EDN91591.1 - 4e-05 23.6 2.9 0.00021 21.4 0.1 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EDN91591.1 - 0.0087 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA PF00004.24 EDN91591.1 - 0.028 14.6 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_bind_2 PF13725.1 EDN91591.1 - 0.029 14.4 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Possible tRNA binding domain AAA_22 PF13401.1 EDN91591.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RRP7 PF12923.2 EDN91592.1 - 1.1e-34 119.2 13.6 1.1e-34 119.2 9.4 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 EDN91592.1 - 0.012 15.5 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 EDN91592.1 - 0.36 9.4 5.7 0.25 9.9 3.0 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RE_HindIII PF09518.5 EDN91593.1 - 0.039 12.8 5.4 0.05 12.4 3.7 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease NCD2 PF04905.8 EDN91593.1 - 0.052 13.3 0.8 0.067 12.9 0.5 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Mnd1 PF03962.10 EDN91593.1 - 0.57 9.8 5.7 0.81 9.3 4.0 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4463 PF14703.1 EDN91593.1 - 1.6 9.2 7.9 6.8 7.2 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) DASH_Dad2 PF08654.5 EDN91594.1 - 6e-30 103.2 0.8 7e-30 103.0 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 EDN91594.1 - 0.039 13.5 0.1 0.054 13.0 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 HAUS2 PF15003.1 EDN91594.1 - 0.065 12.2 0.0 0.077 12.0 0.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 FlxA PF14282.1 EDN91594.1 - 0.29 11.1 2.1 4.6 7.2 1.9 2.0 1 1 1 2 2 2 0 FlxA-like protein Shugoshin_N PF07558.6 EDN91595.1 - 3.5e-15 55.4 8.1 7.9e-15 54.3 5.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EDN91595.1 - 1.8e-11 43.2 4.3 1.8e-11 43.2 3.0 3.4 4 0 0 4 4 4 1 Shugoshin C terminus Metallophos_2 PF12850.2 EDN91596.1 - 1.8e-13 50.6 0.0 2.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short PF00106.20 EDN91598.1 - 1.7e-22 80.1 0.0 2.1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN91598.1 - 1.4e-08 34.6 0.0 3.3e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN91598.1 - 9e-07 29.0 0.1 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EDN91598.1 - 9.5e-06 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EDN91598.1 - 0.0053 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EDN91598.1 - 0.0067 15.3 0.2 0.0095 14.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EDN91598.1 - 0.0089 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EDN91598.1 - 0.021 14.2 0.0 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDN91598.1 - 0.049 13.4 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EDN91598.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FTA4 PF13093.1 EDN91599.1 - 5.4e-61 205.7 9.2 6.2e-61 205.5 6.4 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF412 PF04217.8 EDN91599.1 - 0.16 11.7 1.4 0.42 10.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF412 DnaI_N PF07319.6 EDN91599.1 - 0.27 11.4 1.7 0.37 11.0 0.0 2.0 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus S4_2 PF13275.1 EDN91599.1 - 0.42 10.2 2.1 23 4.6 0.0 2.8 2 1 0 2 2 2 0 S4 domain ERM PF00769.14 EDN91599.1 - 3.5 7.1 17.0 2.5 7.5 7.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF342 PF03961.8 EDN91599.1 - 9.6 4.4 6.6 9.4 4.5 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Hydrophobin_2 PF06766.6 EDN91600.1 - 0.0002 20.9 7.8 0.00032 20.3 5.3 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_31 PF01055.21 EDN91602.1 - 1.3e-133 446.1 0.2 1.9e-133 445.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN91602.1 - 4.5e-11 42.4 4.2 5.9e-11 42.0 1.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like p450 PF00067.17 EDN91603.1 - 2.8e-46 158.0 0.0 4.1e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3405 PF11885.3 EDN91604.1 - 4.3e-167 556.3 0.7 9.7e-167 555.1 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_28 PF00295.12 EDN91606.1 - 7.8e-95 317.5 18.7 8.8e-95 317.3 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AcetylCoA_hyd_C PF13336.1 EDN91606.1 - 0.13 11.9 3.0 0.3 10.7 2.1 1.6 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain NAD_binding_5 PF07994.7 EDN91608.1 - 2.2e-112 375.3 0.0 2.9e-112 374.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EDN91608.1 - 6.9e-46 154.7 0.3 1.6e-45 153.5 0.2 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Gcw_chp PF09694.5 EDN91608.1 - 0.032 14.0 0.5 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (Gcw_chp) DUF1459 PF07312.6 EDN91608.1 - 0.037 13.9 0.2 0.2 11.6 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) LIM PF00412.17 EDN91610.1 - 1.2e-22 79.7 17.7 2.6e-11 43.4 3.7 2.4 2 0 0 2 2 2 2 LIM domain DDE_1 PF03184.14 EDN91611.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN91611.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN91611.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91611.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN91611.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_6 PF12697.2 EDN91612.1 - 3e-25 89.4 0.0 3.6e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN91612.1 - 4.6e-09 36.1 0.0 8.2e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN91612.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF87 PF01935.12 EDN91614.1 - 0.021 14.6 3.0 0.022 14.6 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF87 Herpes_BLRF2 PF05812.7 EDN91614.1 - 1.8 8.4 8.9 0.3 10.9 0.4 3.1 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EDN91614.1 - 1.8 8.5 7.5 0.78 9.7 0.9 3.1 4 0 0 4 4 4 0 bZIP transcription factor Med7 PF05983.6 EDN91614.1 - 6.9 6.4 11.9 5.1 6.8 0.8 2.9 3 0 0 3 3 3 0 MED7 protein adh_short PF00106.20 EDN91616.1 - 8.6e-14 51.7 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN91616.1 - 0.004 16.9 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN91616.1 - 0.0048 16.5 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN91616.1 - 0.0052 16.2 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDN91616.1 - 0.11 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EDN91617.1 - 3.2e-67 227.0 0.0 3.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 EDN91618.1 - 4.4e-84 281.9 0.0 6.3e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN91618.1 - 3.3e-61 206.7 0.0 1.1e-60 204.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN91618.1 - 6.9e-22 77.1 0.3 7.6e-21 73.8 0.2 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EDN91618.1 - 1.2e-11 44.4 0.0 2.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain MCM PF00493.18 EDN91619.1 - 5.6e-139 462.5 0.1 8.2e-139 462.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EDN91619.1 - 3.6e-34 118.0 43.4 3.6e-34 118.0 30.1 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EDN91619.1 - 2.4e-19 69.9 0.1 5.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN91619.1 - 6.2e-08 32.0 0.1 5.2e-06 25.7 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN91619.1 - 5.9e-06 26.0 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDN91619.1 - 0.00082 18.8 0.3 0.0037 16.7 0.2 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDN91619.1 - 0.0019 17.8 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-HC2 PF13490.1 EDN91620.1 - 0.0046 16.8 0.3 0.0095 15.8 0.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger Aconitase PF00330.15 EDN91623.1 - 3.7e-67 226.8 0.1 1.3e-42 145.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN91623.1 - 8.4e-25 87.3 0.0 1.6e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CAP PF00188.21 EDN91624.1 - 8.2e-30 103.8 7.6 3.6e-21 75.9 0.2 3.4 3 1 0 3 3 3 2 Cysteine-rich secretory protein family DUF1479 PF07350.7 EDN91625.1 - 8.6e-167 554.8 0.0 9.8e-167 554.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EDN91627.1 - 2.9e-08 32.9 0.1 4.7e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91627.1 - 0.084 12.7 7.0 0.16 11.8 4.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2158 PF09926.4 EDN91628.1 - 0.098 12.1 6.0 7 6.1 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized small protein (DUF2158) DUF4219 PF13961.1 EDN91629.1 - 0.07 12.5 0.0 0.26 10.7 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TctB PF07331.6 EDN91632.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family YbgT_YccB PF08173.6 EDN91634.1 - 0.38 10.6 1.8 0.8 9.5 1.3 1.5 1 0 0 1 1 1 0 Membrane bound YbgT-like protein HA2 PF04408.18 EDN91635.1 - 4.6e-23 81.1 0.1 1.2e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDN91635.1 - 1.8e-21 76.0 0.0 3.1e-20 72.1 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDN91635.1 - 8.3e-11 41.6 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDN91635.1 - 2.6e-05 24.3 0.0 5.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EDN91635.1 - 0.0002 20.9 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase cobW PF02492.14 EDN91635.1 - 0.0029 17.0 0.1 0.058 12.8 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDN91635.1 - 0.027 14.3 0.0 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EDN91635.1 - 0.032 13.1 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EDN91635.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDN91635.1 - 0.059 13.6 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN91635.1 - 0.062 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain GTP_EFTU PF00009.22 EDN91635.1 - 0.067 12.6 0.1 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EDN91635.1 - 0.069 13.0 1.0 4.3 7.2 0.1 3.4 3 1 0 3 3 3 0 AAA domain Cornichon PF03311.9 EDN91637.1 - 0.0041 17.2 0.3 0.0048 17.0 0.2 1.2 1 0 0 1 1 1 1 Cornichon protein DUF1212 PF06738.7 EDN91641.1 - 4.3e-55 186.1 6.9 4e-54 183.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EDN91641.1 - 1.4e-28 99.3 9.3 1.4e-28 99.3 6.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Hexapep PF00132.19 EDN91644.1 - 2.4e-09 36.2 14.7 6e-06 25.5 3.7 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN91644.1 - 3.2e-08 32.9 7.9 4.6e-07 29.2 1.3 2.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EDN91644.1 - 0.11 11.0 0.1 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Meth_synt_2 PF01717.13 EDN91646.1 - 4.3e-15 55.5 0.0 1.7e-12 46.9 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDN91646.1 - 1.9e-05 24.1 0.4 0.028 13.6 0.0 3.3 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain EamA PF00892.15 EDN91647.1 - 4.3e-13 49.4 27.8 9.3e-08 32.1 11.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDN91647.1 - 4.1e-05 23.7 0.3 4.1e-05 23.7 0.2 3.1 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EDN91647.1 - 0.008 15.3 0.1 0.021 13.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EDN91647.1 - 0.012 15.2 17.4 0.021 14.5 5.4 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family UAA PF08449.6 EDN91647.1 - 0.015 14.2 5.5 0.26 10.1 0.3 2.1 2 0 0 2 2 2 0 UAA transporter family Aldo_ket_red PF00248.16 EDN91648.1 - 8.6e-40 136.3 0.0 2.1e-39 135.0 0.0 1.4 1 1 1 2 2 2 1 Aldo/keto reductase family Ank PF00023.25 EDN91649.1 - 1.6e-12 46.5 1.3 3.1e-06 26.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EDN91649.1 - 7e-12 45.1 0.1 7.9e-07 29.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN91649.1 - 2.6e-10 40.5 0.0 6.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN91649.1 - 1.7e-07 30.7 0.1 0.013 15.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat KilA-N PF04383.8 EDN91649.1 - 2.6e-07 30.2 0.2 1.5e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain Ank_4 PF13637.1 EDN91649.1 - 2.6e-06 27.7 0.6 1.1e-05 25.8 0.4 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TauD PF02668.11 EDN91650.1 - 5.6e-44 150.7 0.0 7e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SHS2_FTSA PF02491.15 EDN91650.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Adenylate_cycl PF01295.13 EDN91650.1 - 0.43 8.7 1.7 0.62 8.2 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I MFS_1 PF07690.11 EDN91651.1 - 2.4e-21 75.8 17.9 3.1e-21 75.4 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.16 EDN91652.1 - 2.2e-34 118.8 7.5 3e-34 118.4 5.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF3848 PF12959.2 EDN91652.1 - 0.028 14.3 0.2 0.08 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) DUF1869 PF08956.5 EDN91652.1 - 0.031 13.8 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Oxidored_FMN PF00724.15 EDN91656.1 - 1.5e-46 158.9 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GTP_cyclohydro2 PF00925.15 EDN91657.1 - 6.3e-58 194.7 0.1 6.1e-53 178.5 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II AA_permease_2 PF13520.1 EDN91658.1 - 1.7e-63 214.6 51.3 2.1e-63 214.3 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN91658.1 - 4e-24 84.8 46.3 5.1e-24 84.4 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Antimicrobial10 PF08105.6 EDN91658.1 - 0.095 12.3 0.2 0.4 10.3 0.1 2.1 1 0 0 1 1 1 0 Metchnikowin family HAMP PF00672.20 EDN91658.1 - 6.5 7.0 8.3 0.83 9.8 0.1 3.6 3 0 0 3 3 3 0 HAMP domain PMI_typeI PF01238.16 EDN91659.1 - 2.5e-145 484.1 0.0 2.9e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.6 EDN91660.1 - 9.7e-24 83.4 0.0 1.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 EDN91660.1 - 0.0024 17.6 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Arf PF00025.16 EDN91661.1 - 1.3e-73 245.9 0.1 1.5e-73 245.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN91661.1 - 5.8e-12 45.1 0.0 7.3e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDN91661.1 - 8.9e-12 44.6 0.0 9.8e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDN91661.1 - 1e-11 44.1 1.8 2.2e-08 33.2 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDN91661.1 - 9.8e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN91661.1 - 9.4e-08 32.5 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN91661.1 - 0.0004 20.3 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EDN91661.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.13 EDN91661.1 - 0.046 12.7 0.1 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF4603 PF15376.1 EDN91662.1 - 0.14 9.3 6.3 0.19 8.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) A_deamin PF02137.13 EDN91662.1 - 1.3 8.2 10.1 8.4 5.6 6.6 1.9 1 1 0 1 1 1 0 Adenosine-deaminase (editase) domain PP28 PF10252.4 EDN91662.1 - 1.8 8.6 18.3 0.24 11.4 8.5 2.2 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 TAF4 PF05236.9 EDN91662.1 - 2.5 7.3 14.7 4.7 6.4 10.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DDE_1 PF03184.14 EDN91663.1 - 2e-23 82.6 0.1 4.3e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN91663.1 - 5e-10 39.0 0.0 5e-10 39.0 0.0 2.4 3 1 0 3 3 3 1 Tc5 transposase DNA-binding domain Pkinase PF00069.20 EDN91664.1 - 1.4e-55 188.2 0.0 1.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91664.1 - 2.1e-25 89.2 0.0 5.4e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN91664.1 - 0.0035 16.3 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 EDN91666.1 - 1.8e-83 280.6 22.8 6.2e-83 278.8 15.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN91666.1 - 1.7e-32 112.5 32.4 5.4e-32 110.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EDN91667.1 - 2e-33 115.4 0.1 3.3e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NDUF_B7 PF05676.8 EDN91668.1 - 3.5e-31 106.4 2.6 6.1e-31 105.6 1.8 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Acyl-CoA_dh_2 PF08028.6 EDN91668.1 - 4.6e-16 59.2 1.3 5.7e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EDN91668.1 - 0.00012 22.1 0.1 0.00023 21.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN91668.1 - 0.03 13.8 0.2 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 EDN91668.1 - 0.04 13.3 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Asp_Glu_race PF01177.17 EDN91669.1 - 2.3e-10 40.7 0.0 2.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 EDN91670.1 - 3.6e-118 394.4 0.0 4.5e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDN91670.1 - 0.052 12.1 0.0 0.31 9.6 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Chitin_synth_2 PF03142.10 EDN91672.1 - 3.2e-75 253.5 0.1 6.2e-75 252.5 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Cyt-b5 PF00173.23 EDN91672.1 - 1.4e-09 37.5 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF639 PF04842.7 EDN91672.1 - 0.041 12.0 0.1 0.057 11.5 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Chitin_synth_2 PF03142.10 EDN91673.1 - 3.1e-104 349.2 6.1 2.1e-59 201.3 0.5 2.0 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN91673.1 - 2.1e-07 30.8 3.5 3e-07 30.3 2.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN91673.1 - 3.4e-05 23.7 0.0 5.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PKD_channel PF08016.7 EDN91675.1 - 0.096 11.0 8.0 2 6.7 0.0 2.2 2 0 0 2 2 2 0 Polycystin cation channel RNase_H PF00075.19 EDN91677.1 - 3.5e-17 62.9 0.0 5.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN91677.1 - 0.036 13.8 0.2 11 5.8 0.0 2.9 3 1 0 3 3 3 0 Reverse transcriptase-like DUF2172 PF09940.4 EDN91677.1 - 0.06 11.7 0.0 0.091 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) GTP_EFTU PF00009.22 EDN91678.1 - 2.8e-09 36.6 0.0 6.1e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SNARE PF05739.14 EDN91679.1 - 0.015 15.0 2.3 0.015 15.0 1.6 2.6 2 0 0 2 2 2 0 SNARE domain zf-RING_2 PF13639.1 EDN91682.1 - 4.1e-12 45.7 2.6 7.7e-12 44.8 1.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN91682.1 - 3.6e-11 42.9 0.6 7.2e-11 42.0 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDN91682.1 - 3.5e-07 30.1 2.3 9.7e-07 28.7 1.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN91682.1 - 2.9e-06 26.9 2.7 4.8e-06 26.2 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN91682.1 - 1.3e-05 24.7 1.7 2.5e-05 23.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN91682.1 - 1.4e-05 24.8 0.4 2.9e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EDN91682.1 - 4.2e-05 23.4 2.8 0.0013 18.6 1.9 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EDN91682.1 - 8.9e-05 22.0 3.5 0.00016 21.2 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDN91682.1 - 0.00089 18.9 1.2 0.0021 17.7 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_RING PF05883.6 EDN91682.1 - 0.079 12.7 0.3 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PRTP PF01366.13 EDN91682.1 - 0.17 9.8 0.1 0.23 9.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein zf-C3HC4_4 PF15227.1 EDN91682.1 - 0.64 9.9 4.7 3.4 7.6 3.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING HA2 PF04408.18 EDN91684.1 - 1.1e-17 63.9 0.0 2.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN91684.1 - 3.8e-14 52.3 0.0 9e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDN91684.1 - 3.4e-12 46.1 0.0 7.7e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Cullin PF00888.17 EDN91685.1 - 1.2e-46 159.4 0.0 1.9e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EDN91685.1 - 4.7e-20 71.5 0.0 2e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Vezatin PF12632.2 EDN91686.1 - 2.5e-19 69.3 0.0 4.8e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF3953 PF13129.1 EDN91688.1 - 2.5 7.7 5.4 0.28 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) tRNA_SAD PF07973.9 EDN91689.1 - 1.1e-06 28.3 0.6 2.1e-06 27.4 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EDN91689.1 - 1.6e-06 26.7 0.1 2.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) TPR_16 PF13432.1 EDN91690.1 - 0.0011 19.6 0.8 0.033 14.8 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN91690.1 - 0.0054 17.2 0.1 15 6.5 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat Nro1 PF12753.2 EDN91690.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Pertussis_S2S3 PF02918.10 EDN91690.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Rab5ip PF07019.7 EDN91691.1 - 1.1e-24 86.3 7.1 1.4e-24 86.0 4.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FA_desaturase PF00487.19 EDN91691.1 - 0.01 15.3 2.8 0.012 15.0 2.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF485 PF04341.7 EDN91691.1 - 0.45 10.2 4.5 0.57 9.9 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF485 Pyr_redox_3 PF13738.1 EDN91692.1 - 2.7e-19 70.0 0.0 2.2e-18 67.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN91692.1 - 1.1e-16 60.2 0.0 5.7e-16 57.8 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EDN91692.1 - 1e-10 41.8 0.0 6.1e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN91692.1 - 4.9e-09 35.5 0.0 5.9e-07 28.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN91692.1 - 5e-08 32.8 1.0 2.9e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN91692.1 - 1.4e-07 31.8 1.5 0.01 16.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN91692.1 - 8.9e-06 24.8 0.3 2.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EDN91692.1 - 0.0022 18.1 0.4 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDN91692.1 - 0.0052 16.4 0.2 0.0086 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EDN91692.1 - 0.015 15.0 4.3 0.024 14.4 0.1 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EDN91692.1 - 0.034 12.6 1.4 0.28 9.5 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EDN91692.1 - 0.08 12.5 0.4 4.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EDN91692.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EDN91692.1 - 0.2 11.9 0.0 0.99 9.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Malic_M PF03949.10 EDN91692.1 - 0.2 11.1 0.2 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.19 EDN91692.1 - 0.21 10.3 3.5 0.068 12.0 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EDN91692.1 - 0.35 9.9 1.4 0.56 9.2 0.2 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 EDN91692.1 - 0.46 9.2 2.5 0.48 9.2 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A CBM_1 PF00734.13 EDN91694.1 - 7.7e-11 41.4 10.2 1.5e-10 40.5 7.1 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Ribosomal_L1 PF00687.16 EDN91697.1 - 1.7e-61 207.3 5.7 1.7e-61 207.3 4.0 2.0 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 EDN91698.1 - 1.4e-53 181.6 0.0 1.9e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 EDN91698.1 - 0.034 13.4 0.0 0.28 10.4 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.6 EDN91698.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.18 EDN91699.1 - 5.7e-13 48.5 0.4 1.4e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain UPF0121 PF03661.8 EDN91700.1 - 0.075 12.2 0.3 0.24 10.5 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Cupin_2 PF07883.6 EDN91701.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Cupin domain Sulfotransfer_3 PF13469.1 EDN91702.1 - 2.4e-06 28.5 0.0 3.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Pyridox_oxidase PF01243.15 EDN91703.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3313 PF11769.3 EDN91703.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Dehydratase_hem PF13816.1 EDN91703.1 - 0.025 13.6 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase TFIID-18kDa PF02269.11 EDN91704.1 - 3.4e-27 94.0 2.0 1.8e-26 91.7 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit MSC PF09402.5 EDN91704.1 - 2.4 6.8 4.9 0.64 8.6 0.5 1.8 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Chitin_bind_4 PF00379.18 EDN91705.1 - 0.0043 17.2 4.7 8.1 6.7 0.1 4.6 3 1 1 4 4 4 2 Insect cuticle protein DUF1213 PF06740.7 EDN91705.1 - 0.059 13.4 1.5 4.4 7.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1213) FTCD_C PF04961.7 EDN91705.1 - 0.2 11.0 1.6 0.41 10.0 1.1 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Toxin_53 PF15532.1 EDN91708.1 - 0.026 14.7 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 Putative toxin 53 Pkinase PF00069.20 EDN91709.1 - 4e-46 157.2 0.0 5e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91709.1 - 1.9e-24 86.1 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN91709.1 - 2.9e-07 30.4 0.0 0.0084 15.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDN91709.1 - 0.0025 17.2 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EDN91709.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like muHD PF10291.4 EDN91710.1 - 2.8e-66 223.3 0.0 7e-66 222.0 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EDN91710.1 - 5e-13 49.0 0.1 2.7e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pkinase PF00069.20 EDN91712.1 - 3e-06 26.5 0.0 3.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91712.1 - 0.00085 18.4 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NmrA PF05368.8 EDN91713.1 - 1.5e-28 99.6 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN91713.1 - 0.0024 17.8 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1049 PF06305.6 EDN91715.1 - 0.046 13.2 1.1 0.085 12.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SRF-TF PF00319.13 EDN91717.1 - 5.6e-07 28.7 0.2 7.6e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.1 EDN91717.1 - 0.12 12.2 0.2 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) HTH_psq PF05225.11 EDN91718.1 - 2.4e-10 39.7 0.1 3.7e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN91718.1 - 4.4e-07 29.5 0.0 7.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 EDN91718.1 - 0.0078 15.8 0.5 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.2 EDN91718.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HisKA PF00512.20 EDN91718.1 - 0.043 13.8 0.3 0.076 13.0 0.2 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain KAR9 PF08580.5 EDN91718.1 - 0.046 11.9 1.3 0.059 11.6 0.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SpoIIID PF12116.3 EDN91718.1 - 0.077 12.9 1.2 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D FAD_binding_4 PF01565.18 EDN91719.1 - 3.5e-21 75.1 0.8 6.7e-21 74.2 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN91719.1 - 1.2e-08 34.7 0.3 2.8e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EDN91719.1 - 0.023 13.8 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding LysM PF01476.15 EDN91720.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain Fungal_trans PF04082.13 EDN91721.1 - 9e-35 119.7 0.0 1.9e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PigN PF04987.9 EDN91722.1 - 5.9e-124 414.0 39.6 3.3e-62 210.5 11.8 3.4 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EDN91722.1 - 3.3e-10 39.8 0.7 1.2e-09 38.0 0.4 1.8 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN91722.1 - 4.8e-08 32.5 0.1 7e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EDN91722.1 - 0.00022 20.7 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 EDN91722.1 - 0.25 10.0 0.1 0.47 9.0 0.1 1.4 1 0 0 1 1 1 0 Alkaline phosphatase PGAP1 PF07819.8 EDN91724.1 - 7e-88 293.9 0.0 1e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EDN91724.1 - 4.9e-06 26.3 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN91724.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN91724.1 - 0.0099 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN91724.1 - 0.039 12.6 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF676 PF05057.9 EDN91724.1 - 0.049 12.9 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 EDN91724.1 - 0.069 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MFS_1 PF07690.11 EDN91725.1 - 3.1e-16 59.0 35.9 7e-13 48.0 10.9 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EDN91725.1 - 1.2e-14 54.1 1.2 2.7e-14 53.0 0.8 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_2 PF13347.1 EDN91725.1 - 0.24 9.7 13.9 0.024 13.0 2.1 2.7 2 1 0 2 2 2 0 MFS/sugar transport protein Serinc PF03348.10 EDN91726.1 - 1.5e-178 593.9 8.1 1.8e-178 593.6 5.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) NAD_synthase PF02540.12 EDN91726.1 - 0.074 11.9 0.0 3.4 6.5 0.0 2.1 2 0 0 2 2 2 0 NAD synthase DUF1077 PF06417.7 EDN91726.1 - 8.3 5.7 7.7 1.1 8.6 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) FAD_binding_4 PF01565.18 EDN91727.1 - 5.3e-33 113.4 1.7 8.2e-33 112.8 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN91727.1 - 4.6e-08 32.8 0.2 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EDN91727.1 - 0.0096 15.0 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding AAA_4 PF04326.9 EDN91727.1 - 0.066 13.3 0.0 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Divergent AAA domain adh_short PF00106.20 EDN91728.1 - 1e-26 93.8 0.1 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN91728.1 - 4.5e-23 82.2 0.0 5.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN91728.1 - 1.3e-05 24.9 0.2 5.1e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN91728.1 - 0.00014 21.3 0.1 0.00043 19.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDN91728.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EDN91728.1 - 0.12 11.9 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDN91728.1 - 0.13 11.3 0.2 0.53 9.4 0.1 2.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 EDN91730.1 - 5.6e-71 238.7 0.0 6.8e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91730.1 - 9.9e-32 110.0 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN91730.1 - 4.3e-05 22.6 0.0 0.00015 20.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN91730.1 - 0.00045 20.0 0.0 0.00096 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN91730.1 - 0.0024 16.8 0.0 0.015 14.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EDN91730.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EDN91731.1 - 2.1e-111 372.0 0.0 1.5e-68 231.0 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EDN91731.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EDN91731.1 - 0.044 13.0 1.5 1.2 8.3 0.0 3.2 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 EDN91732.1 - 7.2e-194 645.6 8.4 9.7e-194 645.2 5.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDN91732.1 - 8.1e-27 92.8 3.4 8.1e-27 92.8 2.4 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain INTS5_C PF14838.1 EDN91732.1 - 0.011 14.1 0.0 0.027 12.7 0.0 1.6 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus WGG PF10273.4 EDN91732.1 - 0.098 12.7 0.7 37 4.4 0.0 3.8 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 FAD_binding_3 PF01494.14 EDN91733.1 - 4.3e-19 68.7 0.1 1.8e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN91733.1 - 1.7e-11 43.6 2.5 4.8e-06 25.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDN91733.1 - 6.3e-08 31.6 0.2 0.00059 18.5 0.1 2.5 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EDN91733.1 - 7.4e-07 28.4 0.1 1.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN91733.1 - 0.00014 21.7 0.3 0.00031 20.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN91733.1 - 0.00018 20.7 0.7 0.0093 15.0 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EDN91733.1 - 0.00019 20.0 0.8 0.046 12.1 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EDN91733.1 - 0.00048 19.1 0.2 0.00076 18.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN91733.1 - 0.0011 17.8 0.0 0.0023 16.7 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EDN91733.1 - 0.0016 18.3 0.2 0.0046 16.8 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN91733.1 - 0.0022 18.3 0.0 0.084 13.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN91733.1 - 0.028 13.5 0.4 0.055 12.5 0.3 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EDN91733.1 - 0.089 11.6 1.1 0.15 10.8 0.5 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EDN91733.1 - 0.24 11.1 0.7 8.4 6.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mmp37 PF09139.6 EDN91734.1 - 3.5e-134 446.9 0.0 4.3e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 EDN91735.1 - 5.5e-48 163.6 53.5 6.9e-48 163.3 37.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein GAS PF13851.1 EDN91735.1 - 8.3 5.5 74.1 0.34 10.0 6.8 5.5 2 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding BIR PF00653.16 EDN91736.1 - 7.3e-43 144.8 6.1 2.8e-21 75.6 0.2 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain G-alpha PF00503.15 EDN91737.1 - 3.1e-110 368.5 0.3 1.9e-107 359.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EDN91737.1 - 2.6e-15 56.0 1.4 1.9e-10 40.2 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN91737.1 - 4.4e-05 22.7 0.3 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN91737.1 - 0.0033 17.8 0.1 0.93 10.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EDN91737.1 - 0.048 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN91737.1 - 0.096 12.1 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phosphorylase PF00343.15 EDN91739.1 - 1.1e-277 922.6 0.5 1.3e-277 922.5 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EDN91739.1 - 0.095 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform ResIII PF04851.10 EDN91741.1 - 5.4e-21 75.2 1.3 6.8e-21 74.9 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN91741.1 - 3.8e-14 52.3 0.0 8.6e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN91741.1 - 3.9e-12 45.9 0.1 7.3e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ndc80_HEC PF03801.8 EDN91741.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 HEC/Ndc80p family Myb_DNA-binding PF00249.26 EDN91742.1 - 0.00021 21.2 0.6 0.00054 19.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.12 EDN91743.1 - 1.4e-33 114.8 0.0 2.6e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EDN91743.1 - 0.00018 21.5 0.1 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EDN91743.1 - 0.015 14.8 0.2 0.015 14.8 0.1 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type DUF904 PF06005.7 EDN91743.1 - 0.49 10.7 4.0 1.6 9.0 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) ETF PF01012.16 EDN91744.1 - 2.1e-40 138.1 0.7 2.6e-40 137.7 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pyr_redox_3 PF13738.1 EDN91745.1 - 4.3e-05 23.6 0.0 0.0044 17.1 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN91745.1 - 5.4e-05 23.1 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SecE PF00584.15 EDN91746.1 - 0.32 10.6 2.0 0.83 9.2 1.4 1.7 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DLIC PF05783.6 EDN91746.1 - 9.4 4.7 7.0 27 3.2 4.5 1.7 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3685 PF12452.3 EDN91748.1 - 1.6 7.8 5.8 6.5 5.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) ATP-synt_F PF01990.12 EDN91752.1 - 3.2e-19 69.1 0.6 1.1e-18 67.3 0.4 1.9 1 1 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EDN91753.1 - 3.1e-25 88.9 0.3 3.6e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EDN91753.1 - 0.0022 18.0 0.1 0.0066 16.4 0.1 1.7 1 1 0 1 1 1 1 ML-like domain CopC PF04234.7 EDN91753.1 - 0.044 14.3 0.0 0.22 12.1 0.0 2.0 2 0 0 2 2 2 0 CopC domain DUF1093 PF06486.6 EDN91753.1 - 0.15 12.4 0.2 14 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1093) WW PF00397.21 EDN91754.1 - 4.6e-05 23.1 3.5 8.1e-05 22.3 2.4 1.4 1 0 0 1 1 1 1 WW domain Dehydrin PF00257.14 EDN91754.1 - 0.025 14.8 8.5 0.087 13.1 5.7 1.8 1 1 1 2 2 2 0 Dehydrin PAT1 PF09770.4 EDN91754.1 - 3.1 5.9 14.7 3.7 5.6 10.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ssl1 PF04056.9 EDN91755.1 - 3.3e-76 255.1 0.0 4.3e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EDN91755.1 - 2.1e-18 66.0 7.6 2.1e-18 66.0 5.3 2.2 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EDN91755.1 - 9.3e-10 38.8 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EDN91755.1 - 0.0038 17.0 5.1 0.0038 17.0 3.5 2.8 2 1 0 2 2 2 1 IBR domain WVELL PF14043.1 EDN91755.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 WVELL protein DZR PF12773.2 EDN91755.1 - 0.55 10.0 21.8 0.13 12.0 3.0 3.4 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EDN91755.1 - 3 7.8 17.6 0.029 14.2 3.1 2.9 2 1 0 2 2 2 0 FYVE zinc finger Chs3p PF12271.3 EDN91756.1 - 8.6e-104 346.6 7.9 9.6e-104 346.4 5.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit YajC PF02699.10 EDN91756.1 - 1 9.0 0.0 1 9.0 0.0 2.5 3 0 0 3 3 3 0 Preprotein translocase subunit SKG6 PF08693.5 EDN91756.1 - 2.9 7.2 5.2 0.44 9.9 0.3 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sugar_tr PF00083.19 EDN91758.1 - 1.2e-101 340.5 21.0 1.4e-101 340.2 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN91758.1 - 2.8e-30 105.2 27.3 8.3e-30 103.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN91758.1 - 0.00064 19.4 0.4 0.0019 17.9 0.1 2.0 2 0 0 2 2 2 1 MFS_1 like family DUF791 PF05631.9 EDN91758.1 - 0.0058 15.3 2.4 0.0094 14.6 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 EDN91758.1 - 0.47 8.4 7.0 0.17 9.9 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector PMT PF02366.13 EDN91759.1 - 9.8e-81 270.7 17.6 9.8e-81 270.7 12.2 2.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDN91759.1 - 1.9e-38 131.9 1.8 2.7e-38 131.4 1.2 1.2 1 0 0 1 1 1 1 MIR domain TIG PF01833.19 EDN91763.1 - 2.7e-14 52.9 0.3 7.4e-14 51.5 0.2 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 EDN91763.1 - 6.7e-12 44.5 0.3 8.5e-07 28.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDN91763.1 - 4.4e-11 42.9 0.0 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN91763.1 - 2.8e-08 33.2 1.0 0.00088 19.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EDN91763.1 - 7.2e-08 32.7 0.1 2.1e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN91763.1 - 1.7e-07 31.2 0.2 9.2e-05 22.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Velvet PF11754.3 EDN91766.1 - 5.2e-67 225.3 0.1 8.5e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 Velvet factor HTH_1 PF00126.22 EDN91768.1 - 0.13 12.0 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TPR_17 PF13431.1 EDN91769.1 - 0.009 16.1 0.8 0.064 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MNE1 PF13762.1 EDN91769.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component TPR_11 PF13414.1 EDN91769.1 - 0.017 14.7 2.9 0.26 10.9 0.4 2.4 2 0 0 2 2 2 0 TPR repeat Glyoxalase PF00903.20 EDN91770.1 - 5.4e-24 84.6 0.1 4.7e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EDN91770.1 - 3.8e-12 46.1 0.0 5.1e-06 26.4 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDN91770.1 - 8.2e-08 32.3 0.0 0.0095 15.8 0.0 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.2 EDN91770.1 - 1e-07 32.5 0.0 0.0037 17.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EDN91770.1 - 2.3e-06 27.5 0.0 3e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Orthopox_A43R PF06517.6 EDN91770.1 - 0.047 13.2 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A43R protein EntA_Immun PF08951.5 EDN91770.1 - 0.1 12.7 0.1 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Enterocin A Immunity 6PF2K PF01591.13 EDN91774.1 - 6.7e-63 211.7 0.0 5.2e-42 143.4 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN91774.1 - 1.8e-26 93.1 0.1 4.6e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDN91774.1 - 0.00026 20.8 0.0 0.003 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDN91774.1 - 0.0018 17.5 0.0 0.084 12.0 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CARD PF00619.16 EDN91774.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain AAA_17 PF13207.1 EDN91774.1 - 0.1 13.4 0.0 0.44 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Cauli_VI PF01693.11 EDN91775.1 - 8.2e-13 48.1 0.1 1.7e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.19 EDN91776.1 - 2.6e-24 86.0 0.1 3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 RNase H DUF4038 PF13204.1 EDN91776.1 - 0.017 14.4 0.3 0.023 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Na_H_Exchanger PF00999.16 EDN91777.1 - 5.5e-37 127.1 19.4 7.4e-37 126.7 13.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3272 PF11676.3 EDN91777.1 - 0.053 13.5 0.4 0.17 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Cu-oxidase_3 PF07732.10 EDN91778.1 - 1.4e-40 137.6 3.5 1.8e-40 137.3 1.2 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EDN91778.1 - 5.1e-24 84.9 0.0 1.1e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN91778.1 - 1.4e-15 57.0 5.0 8.4e-12 44.7 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase DUF1744 PF08490.7 EDN91778.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) C1q PF00386.16 EDN91778.1 - 0.15 12.0 0.3 0.46 10.5 0.3 1.7 2 0 0 2 2 2 0 C1q domain Phosphoesterase PF04185.9 EDN91779.1 - 3.6e-31 108.7 0.3 6.4e-31 107.8 0.2 1.3 1 1 0 1 1 1 1 Phosphoesterase family Glutaredoxin PF00462.19 EDN91780.1 - 1.7e-17 63.1 0.0 4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 EDN91780.1 - 1.2e-11 44.2 0.0 3.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin DUF2561 PF10812.3 EDN91780.1 - 0.068 12.7 0.4 0.095 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CYSTM PF12734.2 EDN91781.1 - 6.9e-11 42.0 21.9 6.9e-11 42.0 15.2 4.3 3 2 1 4 4 4 2 Cysteine-rich TM module stress tolerance Extensin_2 PF04554.8 EDN91781.1 - 0.086 12.7 22.6 0.12 12.2 15.7 1.1 1 0 0 1 1 1 0 Extensin-like region SH3_9 PF14604.1 EDN91782.1 - 6.2e-31 105.7 4.1 1e-15 56.9 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EDN91782.1 - 5e-25 86.6 5.2 1.6e-12 46.5 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EDN91782.1 - 3.6e-15 55.1 0.1 2.4e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EDN91782.1 - 6.7e-12 45.4 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box PF00646.28 EDN91783.1 - 0.00059 19.4 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN91783.1 - 0.00073 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like TrkH PF02386.11 EDN91784.1 - 6.3e-116 386.8 7.2 6.3e-116 386.8 5.0 2.1 2 0 0 2 2 2 2 Cation transport protein Hid1 PF12722.2 EDN91786.1 - 4.7e-195 649.9 12.2 9.4e-114 380.9 0.1 3.5 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EDN91786.1 - 3.9e-55 187.2 1.3 2.7e-31 108.4 0.0 2.8 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 EDN91786.1 - 5.3e-37 126.8 0.0 1.9e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore complex component CytochromB561_N PF09786.4 EDN91786.1 - 0.012 14.1 0.0 0.022 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal AMP-binding PF00501.23 EDN91787.1 - 1.3e-14 53.4 0.1 1.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme PH PF00169.24 EDN91789.1 - 4e-05 23.7 0.6 0.00016 21.8 0.4 2.1 1 0 0 1 1 1 1 PH domain AsmA_2 PF13502.1 EDN91792.1 - 0.0012 18.2 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 AsmA-like C-terminal region DUF4166 PF13761.1 EDN91792.1 - 0.029 14.2 0.1 5.4 6.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4166) DctA-YdbH PF11739.3 EDN91792.1 - 0.09 12.2 0.0 0.55 9.6 0.0 1.9 1 1 0 1 1 1 0 Dicarboxylate transport Fn3-like PF14310.1 EDN91792.1 - 0.44 10.5 5.8 2.9e+02 1.4 4.0 3.4 1 1 0 1 1 1 0 Fibronectin type III-like domain RmlD_sub_bind PF04321.12 EDN91793.1 - 3.9e-53 180.1 0.0 5e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EDN91793.1 - 2.5e-24 85.9 0.0 5e-24 85.0 0.0 1.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN91793.1 - 1.3e-11 43.9 0.0 4.9e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EDN91793.1 - 1e-10 40.7 0.0 2.5e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN91793.1 - 7.2e-07 28.3 0.1 0.00011 21.2 0.0 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN91793.1 - 7.7e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDN91793.1 - 0.023 14.5 0.3 0.15 11.9 0.2 2.3 1 1 0 1 1 1 0 short chain dehydrogenase Choline_kin_N PF04428.9 EDN91793.1 - 0.029 13.8 0.3 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Choline kinase N terminus NmrA PF05368.8 EDN91793.1 - 0.12 11.6 0.1 3.4 6.8 0.0 2.3 2 1 0 2 2 2 0 NmrA-like family Pro-kuma_activ PF09286.6 EDN91794.1 - 2.6e-32 111.8 0.4 1.7e-30 105.9 0.0 2.7 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN91794.1 - 7.2e-08 31.9 4.4 1.5e-07 30.8 3.1 1.5 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_61 PF03443.9 EDN91795.1 - 1.9e-42 145.5 0.2 3.6e-42 144.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EDN91795.1 - 7.7e-05 22.2 5.5 7.7e-05 22.2 3.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2436 PF10365.4 EDN91795.1 - 0.03 13.9 0.6 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) Mucin PF01456.12 EDN91795.1 - 0.18 11.6 19.9 0.54 10.0 12.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DEC-1_N PF04625.8 EDN91795.1 - 0.78 8.3 3.2 1.2 7.7 2.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_11 PF13414.1 EDN91796.1 - 6.5e-14 51.3 3.0 2.2e-07 30.4 0.3 4.1 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EDN91796.1 - 8.4e-10 37.8 6.3 0.0052 16.3 0.5 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN91796.1 - 7e-09 36.1 7.3 7.7e-06 26.4 0.7 3.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN91796.1 - 7.2e-08 31.7 13.2 1.2 9.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN91796.1 - 1.1e-06 28.5 9.7 0.047 13.6 1.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN91796.1 - 2.9e-06 27.3 8.9 0.17 12.5 0.0 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN91796.1 - 3.3e-06 26.8 6.0 0.00066 19.4 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN91796.1 - 6.2e-06 26.2 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EDN91796.1 - 2.9e-05 23.5 6.4 0.0054 16.4 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN91796.1 - 4.9e-05 23.5 2.4 3.3 8.1 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EDN91796.1 - 0.0004 20.2 1.7 0.0021 17.8 0.1 2.7 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 EDN91796.1 - 0.0011 18.5 7.1 3.3 7.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN91796.1 - 0.0014 18.6 0.4 0.68 10.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDN91796.1 - 0.064 13.1 0.4 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1955 PF09205.5 EDN91796.1 - 0.084 12.3 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_6 PF13174.1 EDN91796.1 - 0.25 11.9 13.7 31 5.3 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat APC8 PF04049.8 EDN91797.1 - 2.6e-36 124.4 0.0 3.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 polyprenyl_synt PF00348.12 EDN91798.1 - 2.2e-70 236.4 0.0 2.7e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Cutinase PF01083.17 EDN91800.1 - 2.7e-53 180.3 1.2 3.1e-53 180.1 0.9 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EDN91800.1 - 0.001 18.6 0.2 0.0017 17.9 0.1 1.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EDN91800.1 - 0.0044 16.5 0.1 0.0055 16.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EDN91800.1 - 0.045 13.9 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.2 EDN91800.1 - 0.047 13.4 0.2 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EDN91800.1 - 0.05 12.9 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.6 EDN91800.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EDN91800.1 - 0.12 11.8 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Hpre_diP_synt_I PF07456.6 EDN91800.1 - 0.19 11.5 3.2 0.65 9.8 0.4 2.2 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I Glyco_hydro_16 PF00722.16 EDN91802.1 - 5.5e-43 146.4 3.2 8.9e-43 145.7 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4381 PF14316.1 EDN91802.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) C_GCAxxG_C_C PF09719.5 EDN91802.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Alpha_kinase PF02816.13 EDN91804.1 - 1.4e-38 132.4 0.0 1.7e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family CutC PF03932.9 EDN91805.1 - 2.5e-27 95.4 0.0 4.6e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 CutC family Amino_oxidase PF01593.19 EDN91805.1 - 0.17 10.8 0.9 1 8.3 0.0 1.9 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Omega-toxin PF06357.6 EDN91807.1 - 0.068 12.7 0.6 0.13 11.8 0.4 1.5 1 0 0 1 1 1 0 Omega-atracotoxin ODV-E18 PF10717.4 EDN91807.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF642 PF04862.7 EDN91808.1 - 0.12 12.0 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF642) DUF972 PF06156.8 EDN91809.1 - 0.14 12.5 2.9 0.21 11.9 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EDN91809.1 - 6.1 6.8 17.1 0.074 13.0 1.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.20 EDN91811.1 - 5.2e-71 238.8 0.0 9.8e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN91811.1 - 5.9e-35 120.5 0.0 1.2e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN91811.1 - 0.00016 20.7 0.1 0.00068 18.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EDN91811.1 - 0.0015 17.5 0.1 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN91811.1 - 0.025 14.3 0.8 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MCM PF00493.18 EDN91812.1 - 4.1e-142 472.8 0.1 5.2e-142 472.5 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EDN91812.1 - 3.4e-07 29.6 0.0 0.00017 20.8 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN91812.1 - 2.1e-05 24.2 0.0 4.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN91812.1 - 0.0003 20.3 0.1 0.0015 18.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDN91812.1 - 0.016 14.7 0.0 0.74 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EDN91812.1 - 0.064 13.4 0.2 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SopD PF11047.3 EDN91812.1 - 0.089 11.7 0.0 3.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Salmonella outer protein D DUF2450 PF10475.4 EDN91813.1 - 2.4e-08 33.2 1.4 6.1e-08 31.9 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 EDN91813.1 - 0.0024 17.4 1.5 0.0041 16.6 1.1 1.3 1 0 0 1 1 1 1 LUC7 N_terminus Sec8_exocyst PF04048.9 EDN91813.1 - 0.0049 16.5 1.1 0.015 14.9 0.8 1.8 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain FliJ PF02050.11 EDN91813.1 - 0.026 14.5 1.0 0.094 12.7 0.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.6 EDN91813.1 - 0.038 12.6 1.5 0.071 11.7 1.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SpoVR PF04293.8 EDN91813.1 - 0.058 11.7 0.1 0.12 10.7 0.1 1.4 1 0 0 1 1 1 0 SpoVR like protein DUF904 PF06005.7 EDN91813.1 - 6.1 7.2 14.3 0.75 10.1 2.8 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF904) Vps54 PF07928.7 EDN91814.1 - 2.7e-32 111.7 0.8 3.9e-32 111.1 0.1 1.6 2 0 0 2 2 2 1 Vps54-like protein XRN_N PF03159.13 EDN91815.1 - 5.4e-102 340.1 0.1 8.6e-102 339.5 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Astro_capsid PF03115.9 EDN91815.1 - 4.4 5.4 5.0 6.5 4.8 3.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor WD40 PF00400.27 EDN91816.1 - 1.4e-38 129.3 0.7 7e-09 35.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDN91816.1 - 1.4e-30 104.9 0.2 4e-30 103.5 0.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EDN91816.1 - 0.00071 17.8 0.2 0.21 9.6 0.0 2.5 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DDE_1 PF03184.14 EDN91819.1 - 1.4e-49 168.2 0.0 2.8e-49 167.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN91819.1 - 1.6e-08 33.9 0.8 5.5e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN91819.1 - 1.9e-07 30.7 0.1 7.9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN91819.1 - 3.8e-07 29.9 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN91819.1 - 0.022 14.6 7.3 0.048 13.6 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_24 PF13412.1 EDN91819.1 - 0.023 14.0 0.2 0.059 12.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fungal_trans PF04082.13 EDN91820.1 - 1.5e-19 69.9 0.2 2.8e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN91820.1 - 6.4e-06 25.9 11.5 1.2e-05 25.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OSR1_C PF12202.3 EDN91824.1 - 0.025 14.2 0.6 0.047 13.3 0.4 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal F-box-like PF12937.2 EDN91828.1 - 3.2e-06 26.7 0.8 1.1e-05 25.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN91828.1 - 0.0016 18.0 5.3 0.032 13.8 3.7 2.6 1 1 0 1 1 1 1 F-box domain 4HBT PF03061.17 EDN91831.1 - 1.7e-09 37.6 0.1 2.8e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EDN91831.1 - 0.00036 20.3 0.0 0.00043 20.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Cnd3 PF12719.2 EDN91832.1 - 4.1e-96 321.4 1.3 1.4e-95 319.7 0.8 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EDN91832.1 - 4.5e-10 39.6 11.8 2e-05 24.7 0.9 5.4 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EDN91832.1 - 4.9e-07 29.2 5.5 0.55 10.4 0.0 6.9 6 0 0 6 6 6 1 HEAT repeat DUF4226 PF10774.4 EDN91832.1 - 0.0085 16.1 1.0 0.24 11.4 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4226) Gp_UL130 PF11668.3 EDN91832.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Tom37_C PF11801.3 EDN91832.1 - 0.35 10.7 5.8 1.7 8.5 0.1 3.6 3 0 0 3 3 3 0 Tom37 C-terminal domain PALP PF00291.20 EDN91833.1 - 1.5e-61 208.3 0.0 1.8e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Nucleoporin_FG PF13634.1 EDN91836.1 - 0.088 13.0 10.3 0.13 12.4 7.1 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region AAA PF00004.24 EDN91837.1 - 8.4e-41 139.2 0.0 2.5e-17 63.3 0.0 4.4 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN91837.1 - 7.4e-14 52.0 8.1 0.0066 16.5 0.0 7.1 4 3 1 5 5 5 3 AAA domain AAA_17 PF13207.1 EDN91837.1 - 1.3e-13 51.8 0.5 0.0048 17.7 0.0 4.2 3 0 0 3 3 3 3 AAA domain AAA_5 PF07728.9 EDN91837.1 - 1.5e-10 40.9 0.0 0.016 14.9 0.0 4.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN91837.1 - 1e-09 37.9 0.2 0.026 14.2 0.0 4.0 3 0 0 3 3 3 2 Part of AAA domain RuvB_N PF05496.7 EDN91837.1 - 4.1e-09 35.8 0.0 0.0041 16.1 0.0 3.6 3 0 0 3 3 3 3 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EDN91837.1 - 1.8e-08 34.5 0.3 0.32 11.2 0.0 3.8 3 0 0 3 3 3 3 RNA helicase AAA_33 PF13671.1 EDN91837.1 - 2.3e-07 30.7 0.3 0.38 10.6 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_14 PF13173.1 EDN91837.1 - 2.6e-07 30.6 0.0 0.013 15.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EDN91837.1 - 5.8e-07 29.6 0.1 0.53 10.2 0.0 4.1 3 0 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.16 EDN91837.1 - 7.4e-07 28.5 0.2 0.47 9.5 0.0 3.8 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EDN91837.1 - 2.6e-06 27.3 0.1 0.4 10.5 0.0 3.4 3 0 0 3 3 3 2 Torsin IstB_IS21 PF01695.12 EDN91837.1 - 5.3e-06 25.9 0.0 0.75 9.1 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_30 PF13604.1 EDN91837.1 - 2.5e-05 23.9 12.0 0.24 10.9 0.1 4.9 5 1 0 5 5 3 3 AAA domain AAA_28 PF13521.1 EDN91837.1 - 6.1e-05 23.0 1.0 0.16 11.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.21 EDN91837.1 - 0.00015 21.2 0.3 10 5.5 0.0 4.6 4 1 0 4 4 4 0 Sigma-54 interaction domain PhoH PF02562.11 EDN91837.1 - 0.00018 20.8 0.1 1.8 7.7 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein ABC_tran PF00005.22 EDN91837.1 - 0.00027 21.2 0.3 0.99 9.6 0.0 4.0 3 0 0 3 3 3 1 ABC transporter Viral_helicase1 PF01443.13 EDN91837.1 - 0.00034 20.2 0.0 0.023 14.2 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EDN91837.1 - 0.0005 19.0 0.1 2.1 7.1 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein MobB PF03205.9 EDN91837.1 - 0.00055 19.6 1.2 1.1 8.9 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EDN91837.1 - 0.00099 18.7 7.3 1.1 8.7 0.3 3.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EDN91837.1 - 0.0015 18.7 15.4 0.23 11.7 0.0 4.8 5 0 0 5 5 4 2 AAA domain SRP54 PF00448.17 EDN91837.1 - 0.0026 17.2 3.4 0.35 10.2 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain VirE PF05272.6 EDN91837.1 - 0.0082 15.6 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E PEPCK_ATP PF01293.15 EDN91837.1 - 0.016 13.7 0.2 0.053 12.0 0.0 1.9 3 0 0 3 3 3 0 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EDN91837.1 - 0.018 14.5 0.0 3.9 7.0 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain PIF PF05092.7 EDN91837.1 - 0.037 12.4 0.1 0.054 11.8 0.1 1.2 1 0 0 1 1 1 0 Per os infectivity NACHT PF05729.7 EDN91837.1 - 0.064 12.9 0.8 13 5.3 0.0 3.6 3 0 0 3 3 3 0 NACHT domain AAA_3 PF07726.6 EDN91837.1 - 0.071 12.7 0.0 3 7.4 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EDN91837.1 - 0.17 11.4 0.0 0.17 11.4 0.0 4.6 3 1 0 3 3 2 0 AAA domain KaiC PF06745.8 EDN91837.1 - 0.18 10.9 4.0 16 4.5 0.1 3.4 3 0 0 3 3 3 0 KaiC AAA_10 PF12846.2 EDN91837.1 - 0.2 11.0 2.8 15 4.9 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 EDN91837.1 - 7.1 6.4 12.9 3 7.6 0.0 4.0 4 0 0 4 4 3 0 Shikimate kinase BTB PF00651.26 EDN91838.1 - 6.4e-08 32.5 0.1 1.9e-07 31.0 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain Opy2 PF09463.5 EDN91838.1 - 0.1 12.7 2.4 0.16 12.0 0.6 2.1 2 0 0 2 2 2 0 Opy2 protein FAD-oxidase_C PF02913.14 EDN91841.1 - 6.4e-57 192.7 0.0 9.2e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN91841.1 - 7.4e-37 125.9 0.5 1.4e-36 125.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 EDN91842.1 - 7e-55 185.2 0.1 9.4e-55 184.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN91842.1 - 2.5e-13 49.0 0.1 2.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Helicase_C_3 PF13625.1 EDN91843.1 - 9.5e-28 96.5 0.0 2.4e-26 91.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN91843.1 - 9.4e-13 48.3 1.6 1.4e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN91843.1 - 5.4e-12 45.1 0.2 9.7e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN91843.1 - 1.8e-10 40.4 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN91843.1 - 1.7e-05 24.3 1.1 3.1e-05 23.5 0.1 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase VIT1 PF01988.14 EDN91844.1 - 5.9e-05 22.6 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 VIT family DUF3382 PF11862.3 EDN91844.1 - 0.15 11.9 2.8 0.29 11.0 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) dDENN PF03455.14 EDN91844.1 - 0.16 12.0 0.2 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 dDENN domain NUDIX-like PF09296.6 EDN91847.1 - 1.6e-17 63.6 0.0 3.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EDN91847.1 - 2.2e-15 56.4 0.1 3.7e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EDN91847.1 - 2.4e-09 36.5 1.4 4.2e-09 35.7 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.9 EDN91848.1 - 2.7e-37 126.1 22.2 1.8e-19 69.0 2.3 3.0 3 0 0 3 3 3 2 PQ loop repeat TspO_MBR PF03073.10 EDN91848.1 - 0.025 14.0 0.4 0.025 14.0 0.3 2.4 2 1 0 2 2 2 0 TspO/MBR family DUF805 PF05656.9 EDN91848.1 - 0.26 11.1 4.8 0.2 11.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF4048 PF13257.1 EDN91849.1 - 1.3e-16 61.0 19.8 2.5e-12 46.9 0.2 3.8 4 0 0 4 4 4 3 Domain of unknown function (DUF4048) DNA_ligase_A_N PF04675.9 EDN91850.1 - 0.00035 20.4 0.0 0.00074 19.3 0.0 1.6 1 1 0 1 1 1 1 DNA ligase N terminus WD40 PF00400.27 EDN91851.1 - 4.2e-53 175.4 28.0 1.1e-12 47.3 0.1 11.9 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 EDN91851.1 - 2.3e-26 91.8 0.0 3.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EDN91851.1 - 0.0001 20.6 2.2 3 5.8 0.0 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 IKI3 PF04762.7 EDN91851.1 - 0.0059 14.4 0.0 1.2 6.8 0.0 2.5 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 EDN91851.1 - 0.014 14.5 0.1 2.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EDN91851.1 - 0.035 12.3 0.1 1.8 6.7 0.0 3.4 3 1 1 4 4 4 0 Cytochrome D1 heme domain Septin PF00735.13 EDN91852.1 - 3.8e-115 383.7 0.1 3.8e-115 383.7 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDN91852.1 - 2.1e-07 30.8 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN91852.1 - 4.8e-06 26.1 0.1 8e-05 22.1 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN91852.1 - 1.9e-05 23.8 0.0 5.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EDN91852.1 - 0.0028 18.1 0.0 0.0093 16.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EDN91852.1 - 0.0028 17.7 0.1 0.0097 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDN91852.1 - 0.0031 17.1 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EDN91852.1 - 0.0048 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EDN91852.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EDN91852.1 - 0.0064 15.3 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EDN91852.1 - 0.013 14.7 0.1 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 EDN91852.1 - 0.023 13.5 0.2 0.073 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EDN91852.1 - 0.025 13.9 0.4 0.073 12.4 0.2 1.9 2 1 0 2 2 1 0 Ras family NACHT PF05729.7 EDN91852.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 EDN91852.1 - 0.044 13.6 5.7 0.86 9.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.22 EDN91852.1 - 0.045 14.0 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 EDN91852.1 - 0.08 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EDN91852.1 - 0.093 12.4 2.2 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EDN91852.1 - 0.096 12.6 0.9 0.52 10.2 0.0 2.4 2 1 0 3 3 3 0 AAA ATPase domain KAP_NTPase PF07693.9 EDN91852.1 - 0.11 11.4 1.8 0.19 10.7 1.2 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EDN91852.1 - 0.12 11.1 2.5 0.95 8.1 0.0 2.7 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 EDN91852.1 - 0.13 11.6 1.2 2.9 7.3 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EDN91852.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EDN91852.1 - 0.17 11.4 0.8 9.6 5.6 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Myc-LZ PF02344.10 EDN91852.1 - 1.6 8.4 6.4 0.85 9.2 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain HATPase_c PF02518.21 EDN91853.1 - 2.1e-12 46.7 0.0 1.5e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDN91853.1 - 0.00045 19.8 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EDN91853.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PP2C PF00481.16 EDN91854.1 - 1e-55 188.8 0.0 2.2e-55 187.8 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EDN91854.1 - 2.6e-46 154.5 53.1 4.9e-07 29.2 1.0 12.5 8 2 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN91854.1 - 1.3e-37 127.3 51.8 7.9e-11 41.5 0.9 9.5 5 3 7 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 EDN91854.1 - 3.3e-25 88.5 0.0 8.1e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EDN91854.1 - 3e-24 81.2 49.4 0.034 14.1 0.0 19.1 19 0 0 19 19 19 7 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EDN91854.1 - 9.7e-20 69.6 2.2 3.7e-19 67.7 1.5 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 EDN91854.1 - 5.2e-12 46.0 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EDN91854.1 - 1.6e-09 36.3 54.3 0.49 10.8 0.1 16.4 18 0 0 18 18 18 3 Leucine rich repeat LRR_9 PF14580.1 EDN91854.1 - 0.013 15.0 12.4 0.034 13.6 0.2 4.2 2 1 2 4 4 4 0 Leucine-rich repeat CFEM PF05730.6 EDN91855.1 - 2.4e-14 52.8 16.7 5.2e-14 51.8 11.2 1.8 2 0 0 2 2 2 1 CFEM domain DDE_1 PF03184.14 EDN91856.1 - 1.1e-49 168.5 0.0 2.4e-49 167.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN91856.1 - 1.5e-10 40.4 0.4 1.6e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN91856.1 - 1.2e-07 31.3 0.1 5.6e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN91856.1 - 3.7e-05 23.5 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN91856.1 - 0.023 14.5 7.0 0.051 13.5 4.9 1.6 1 0 0 1 1 1 0 Zinc knuckle NUMOD1 PF07453.8 EDN91856.1 - 0.068 13.0 0.2 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 NUMOD1 domain MSC PF09402.5 EDN91857.1 - 4.7e-99 331.2 0.0 6.6e-99 330.7 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EDN91857.1 - 1.5e-16 59.6 0.1 4.6e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain Arylsulfotran_2 PF14269.1 EDN91857.1 - 0.043 12.9 0.1 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) HSP20 PF00011.16 EDN91859.1 - 1.6e-13 50.4 0.2 3.5e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FAD_binding_4 PF01565.18 EDN91860.1 - 7.2e-18 64.4 0.5 1.6e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN91860.1 - 4.4e-11 42.5 1.2 1.2e-10 41.1 0.8 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EDN91860.1 - 0.0048 16.0 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding MSP1_C PF07462.6 EDN91862.1 - 2.9 6.1 11.7 4.8 5.4 8.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CUE PF02845.11 EDN91864.1 - 7.9e-12 44.4 0.0 1.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain FAD-oxidase_C PF02913.14 EDN91864.1 - 0.34 10.1 2.3 0.57 9.4 1.6 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain CDC73 PF05179.9 EDN91866.1 - 3.3e-42 144.7 0.0 1.4e-41 142.6 0.0 1.9 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family WD40 PF00400.27 EDN91868.1 - 1.4e-19 69.1 0.1 7.2e-05 22.5 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat UPF0560 PF10577.4 EDN91868.1 - 0.084 11.1 0.6 0.22 9.7 0.0 1.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0560 Glycos_transf_4 PF00953.16 EDN91869.1 - 2.2e-31 108.8 10.4 2.2e-31 108.8 7.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 PHD PF00628.24 EDN91870.1 - 8.9e-06 25.3 11.5 1.7e-05 24.3 8.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN91870.1 - 0.1 11.9 3.9 0.27 10.5 2.7 1.7 1 0 0 1 1 1 0 PHD-finger SUFU_C PF12470.3 EDN91870.1 - 0.73 9.3 8.1 0.033 13.7 0.8 2.2 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain EBP PF05241.7 EDN91872.1 - 1.5e-60 203.5 9.1 1.8e-60 203.2 6.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein Ribosomal_L32p PF01783.18 EDN91874.1 - 0.033 14.3 0.9 0.054 13.6 0.6 1.3 1 0 0 1 1 1 0 Ribosomal L32p protein family RhoGAP PF00620.22 EDN91875.1 - 1.9e-36 124.9 0.0 4.4e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EDN91875.1 - 0.0002 21.3 16.4 0.00046 20.2 9.0 2.6 2 1 0 2 2 2 1 LIM domain SspB PF04386.8 EDN91876.1 - 0.44 10.1 2.4 0.95 9.0 1.7 1.5 1 0 0 1 1 1 0 Stringent starvation protein B SPC25 PF06703.6 EDN91878.1 - 5.4e-56 188.6 0.0 6.8e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EDN91879.1 - 3.1e-31 108.1 3.3 4.7e-31 107.5 2.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 BTB PF00651.26 EDN91880.1 - 0.054 13.4 0.1 1.4 8.9 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain Brix PF04427.13 EDN91881.1 - 5.5e-39 133.8 0.3 7.4e-39 133.3 0.2 1.2 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 EDN91882.1 - 1.8e-26 92.6 1.9 2.1e-26 92.4 1.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cellsynth_D PF03500.8 EDN91882.1 - 0.068 12.8 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase subunit D DPPIV_N PF00930.16 EDN91883.1 - 9.7e-107 356.5 0.2 1.4e-106 356.0 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EDN91883.1 - 8.4e-56 188.5 1.4 1.6e-55 187.6 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN91883.1 - 1.6e-09 37.6 0.1 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDN91883.1 - 7.6e-06 25.5 2.0 0.00011 21.7 0.5 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EDN91883.1 - 1.1e-05 25.3 0.0 0.00024 21.0 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EDN91883.1 - 0.00013 20.3 0.0 0.061 11.6 0.0 2.2 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 EDN91883.1 - 0.0012 18.2 0.1 0.003 17.0 0.1 1.6 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 EDN91883.1 - 0.0068 15.7 0.0 0.037 13.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydro_lipase PF04083.11 EDN91883.1 - 0.029 13.7 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.11 EDN91883.1 - 0.12 11.7 0.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AA_permease PF00324.16 EDN91887.1 - 1.1e-62 211.9 25.8 1.2e-62 211.8 17.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN91887.1 - 1.9e-08 33.2 25.1 2.3e-08 33.0 17.4 1.0 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.12 EDN91887.1 - 0.0018 16.8 5.3 0.0024 16.4 3.5 1.3 1 1 0 1 1 1 1 Sodium:alanine symporter family DUF4491 PF14898.1 EDN91887.1 - 0.076 13.1 2.8 0.23 11.6 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) DUF4577 PF15145.1 EDN91887.1 - 0.1 12.5 0.3 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Glyco_hydro_11 PF00457.12 EDN91888.1 - 2.1e-61 206.4 8.3 2.5e-61 206.2 5.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MMS19_C PF12460.3 EDN91889.1 - 1e-34 119.9 1.8 2.6e-32 112.0 0.0 3.2 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EDN91889.1 - 1.1e-15 57.6 1.4 2.1e-14 53.4 0.0 3.3 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II ESAG1 PF03238.8 EDN91889.1 - 0.00011 21.5 0.0 0.00031 20.1 0.0 1.7 1 0 0 1 1 1 1 ESAG protein DUF2450 PF10475.4 EDN91889.1 - 0.02 13.7 0.3 0.27 10.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function N-terminal domain (DUF2450) SF-assemblin PF06705.6 EDN91889.1 - 0.024 13.7 0.3 0.051 12.7 0.2 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin THF_DHG_CYH PF00763.18 EDN91890.1 - 1.3e-21 76.8 0.1 2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EDN91890.1 - 3.7e-16 58.6 0.0 5.7e-10 38.4 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MAPEG PF01124.13 EDN91891.1 - 1.4e-18 66.7 0.3 1.8e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 MAPEG family ELMO_CED12 PF04727.8 EDN91892.1 - 4.4e-50 169.5 0.0 7.7e-50 168.7 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EDN91892.1 - 0.00077 19.2 0.2 0.023 14.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Mito_carr PF00153.22 EDN91894.1 - 1.2e-68 226.8 1.6 4.1e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EDN91895.1 - 7.4e-40 137.2 0.1 9.5e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Rota_NS53 PF00981.12 EDN91895.1 - 0.07 11.7 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Chordopox_A33R PF05966.7 EDN91896.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Cu_bind_like PF02298.12 EDN91897.1 - 0.071 12.9 0.1 1.1 9.1 0.1 2.5 1 1 0 1 1 1 0 Plastocyanin-like domain DUF726 PF05277.7 EDN91897.1 - 0.17 10.7 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RAP1 PF07218.6 EDN91897.1 - 0.86 7.6 9.9 1.6 6.7 6.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 EDN91897.1 - 2 7.1 7.7 2 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Alg6_Alg8 PF03155.10 EDN91898.1 - 3.5e-09 36.0 0.1 4e-09 35.8 0.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DiS_P_DiS PF06750.8 EDN91901.1 - 0.059 13.1 0.6 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PBAN PF05874.6 EDN91904.1 - 0.094 12.0 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Fer4_18 PF13746.1 EDN91906.1 - 0.027 14.8 2.0 0.083 13.3 1.4 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF962 PF06127.6 EDN91907.1 - 9.5e-27 92.7 0.2 2.1e-26 91.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 EDN91909.1 - 2.4e-14 53.1 0.0 4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EDN91909.1 - 2.7e-12 46.5 0.0 3.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain KxDL PF10241.4 EDN91910.1 - 0.03 14.2 1.7 0.054 13.3 1.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein Amidoligase_2 PF12224.3 EDN91911.1 - 1.6e-13 50.8 0.1 5.7e-12 45.7 0.1 2.5 1 1 0 1 1 1 1 Putative amidoligase enzyme NAD_binding_6 PF08030.7 EDN91911.1 - 0.096 12.5 0.1 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain SH3BGR PF04908.10 EDN91912.1 - 3.2e-06 26.9 0.0 8.5e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein TPP_enzyme_N PF02776.13 EDN91913.1 - 2.9e-41 140.8 0.1 7.5e-41 139.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN91913.1 - 8.3e-34 116.2 0.1 1.7e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN91913.1 - 6.1e-21 74.6 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EDN91913.1 - 0.00021 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit B12-binding PF02310.14 EDN91913.1 - 0.051 13.4 2.6 1 9.2 0.3 2.8 2 0 0 2 2 2 0 B12 binding domain Ank PF00023.25 EDN91915.1 - 2.7e-08 33.1 0.0 1.6e-06 27.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EDN91915.1 - 3.8e-07 30.3 0.0 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN91915.1 - 8.6e-07 29.3 0.1 3.4e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN91915.1 - 2e-06 27.8 0.0 4.9e-05 23.4 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN91915.1 - 1.5e-05 24.7 0.0 0.037 14.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat DUF745 PF05335.8 EDN91915.1 - 0.027 13.9 0.7 0.027 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Prefoldin_3 PF13758.1 EDN91915.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit DUF3199 PF11436.3 EDN91915.1 - 0.093 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) DUF1843 PF08898.5 EDN91915.1 - 0.099 12.6 0.1 0.45 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF948 PF06103.6 EDN91915.1 - 0.11 12.4 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Mem_trans PF03547.13 EDN91916.1 - 6.2 5.0 5.0 11 4.1 3.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF3328 PF11807.3 EDN91921.1 - 5.6e-50 170.0 0.2 7.4e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cu_bind_like PF02298.12 EDN91923.1 - 0.0072 16.0 0.2 0.024 14.4 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 EDN91923.1 - 0.035 14.3 0.2 0.14 12.4 0.2 2.0 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Fungal_trans_2 PF11951.3 EDN91924.1 - 1.6e-06 27.0 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ORC5_C PF14630.1 EDN91925.1 - 9.4e-75 251.5 0.0 1.3e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EDN91925.1 - 8.6e-07 29.1 0.1 3.4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EDN91925.1 - 0.0016 17.4 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 EDN91925.1 - 0.11 12.1 0.1 1 9.0 0.0 2.4 3 1 1 4 4 4 0 NACHT domain 6PF2K PF01591.13 EDN91925.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2051 PF09738.4 EDN91926.1 - 0.043 13.0 0.7 0.08 12.2 0.5 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Packaging_FI PF14000.1 EDN91926.1 - 0.063 13.4 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 DNA packaging protein FI DUF382 PF04037.8 EDN91927.1 - 1.4e-62 209.2 0.7 4.2e-62 207.6 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EDN91927.1 - 5.3e-21 73.7 6.2 1.2e-20 72.5 4.3 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.11 EDN91928.1 - 1.2e-37 128.9 2.7 1.2e-37 128.9 1.8 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDN91928.1 - 5.7e-11 41.8 13.9 1.1e-09 37.7 9.6 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EDN91928.1 - 1.4e-05 25.1 30.3 0.0094 15.9 6.9 3.2 2 2 1 3 3 3 2 EamA-like transporter family Tom37_C PF11801.3 EDN91929.1 - 2.1 8.2 10.4 1.7 8.4 2.0 2.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Nucleoplasmin PF03066.10 EDN91929.1 - 2.7 7.4 24.6 0.42 10.1 7.4 3.3 3 0 0 3 3 3 0 Nucleoplasmin FAM176 PF14851.1 EDN91929.1 - 2.9 7.5 27.5 0.041 13.5 5.0 3.7 2 1 1 3 3 3 0 FAM176 family Pacs-1 PF10254.4 EDN91929.1 - 3.1 6.3 7.1 5.6 5.4 4.9 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein RXT2_N PF08595.6 EDN91929.1 - 4.9 6.9 23.9 0.7 9.6 6.7 3.3 3 0 0 3 3 3 0 RXT2-like, N-terminal VEFS-Box PF09733.4 EDN91930.1 - 1.1e-09 38.0 0.2 2.2e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 EDN91930.1 - 0.0041 16.7 6.3 0.0041 16.7 4.3 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EDN91930.1 - 1 8.7 4.1 1.9 7.8 1.5 2.2 2 0 0 2 2 2 0 PHD-finger ATP-synt_ab PF00006.20 EDN91932.1 - 1.5e-61 207.6 0.0 2.2e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN91932.1 - 1.8e-23 83.1 0.0 3.3e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDN91932.1 - 1.1e-22 80.0 1.3 1.9e-22 79.2 0.3 1.9 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 EDN91932.1 - 0.0024 17.5 0.0 0.0068 16.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EDN91932.1 - 0.0056 16.1 0.4 0.032 13.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDN91932.1 - 0.016 14.3 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN91932.1 - 0.018 15.0 0.5 0.33 10.9 0.1 2.5 1 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EDN91932.1 - 0.02 14.5 0.1 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EDN91932.1 - 0.025 13.6 0.1 0.048 12.7 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EDN91932.1 - 0.032 14.3 0.1 0.14 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EDN91932.1 - 0.037 13.7 0.2 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDN91932.1 - 0.051 13.7 0.2 2.4 8.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDN91932.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EDN91932.1 - 0.11 11.3 0.7 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EDN91933.1 - 5.5e-25 87.3 0.1 1.3e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EDN91933.1 - 5.2e-16 58.9 4.6 9.1e-14 51.5 0.1 2.9 3 1 1 4 4 4 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EDN91933.1 - 4.7e-11 42.5 0.0 1.4e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AAA_2 PF07724.9 EDN91934.1 - 1.2e-38 132.7 0.0 2.1e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDN91934.1 - 2.3e-14 53.7 0.0 6.2e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN91934.1 - 2.8e-07 30.3 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN91934.1 - 3.3e-06 27.2 0.0 9.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN91934.1 - 3.3e-05 23.3 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDN91934.1 - 6.7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ClpB_D2-small PF10431.4 EDN91934.1 - 0.00039 20.2 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 2 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EDN91934.1 - 0.0011 19.0 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 EDN91934.1 - 0.0012 17.6 0.0 0.0022 16.8 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family Sigma54_activat PF00158.21 EDN91934.1 - 0.003 17.0 0.0 0.04 13.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EDN91934.1 - 0.012 16.4 0.2 0.037 14.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN91934.1 - 0.017 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDN91934.1 - 0.023 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EDN91934.1 - 0.045 12.9 0.1 0.44 9.6 0.0 2.3 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EDN91934.1 - 0.053 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_3 PF07726.6 EDN91934.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) COX4 PF02936.9 EDN91935.1 - 3e-51 172.9 0.0 3.4e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Gp_dh_C PF02800.15 EDN91937.1 - 2.3e-75 251.3 0.2 3.3e-75 250.8 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EDN91937.1 - 5.2e-60 201.7 0.2 9.4e-60 200.9 0.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EDN91937.1 - 0.006 16.4 0.1 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EDN91937.1 - 0.085 12.0 0.1 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hist_deacetyl PF00850.14 EDN91938.1 - 1.3e-86 290.7 0.0 1.8e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EDN91938.1 - 6.9e-47 159.1 0.1 1.3e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Arb2 domain F-box PF00646.28 EDN91939.1 - 1.9e-05 24.1 0.0 4.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain HATPase_c PF02518.21 EDN91940.1 - 1e-23 83.1 0.1 4.5e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN91940.1 - 8.8e-20 70.7 0.1 2.8e-19 69.1 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDN91940.1 - 3.8e-09 36.3 0.2 2e-08 34.1 0.1 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EDN91940.1 - 0.0071 16.3 0.0 0.084 12.9 0.0 2.5 2 0 0 2 2 2 1 PAS fold DUF371 PF04027.8 EDN91943.1 - 0.042 13.5 0.5 0.12 11.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF371) MHC2-interact PF09307.5 EDN91943.1 - 7.8 6.3 12.3 14 5.5 8.5 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting Paf67 PF10255.4 EDN91948.1 - 0.025 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TFIIF_alpha PF05793.7 EDN91949.1 - 0.64 8.3 11.7 1 7.6 8.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BC10 PF06726.7 EDN91950.1 - 5e-17 61.6 12.1 7.5e-17 61.1 8.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 LicD PF04991.8 EDN91951.1 - 5.9e-37 127.7 4.1 1.2e-35 123.5 2.9 2.2 1 1 0 1 1 1 1 LicD family p450 PF00067.17 EDN91954.1 - 9.4e-60 202.4 0.0 1.2e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Claudin_3 PF06653.6 EDN91956.1 - 0.015 15.0 1.4 0.015 15.0 0.9 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF3309 PF11752.3 EDN91956.1 - 0.025 14.3 1.5 0.036 13.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DUF2215 PF10225.4 EDN91956.1 - 0.088 12.2 1.4 0.089 12.2 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) EXS PF03124.9 EDN91956.1 - 0.33 9.9 2.5 0.35 9.8 1.7 1.0 1 0 0 1 1 1 0 EXS family Glycogen_syn PF05693.8 EDN91957.1 - 0 1138.4 0.0 0 1138.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EDN91957.1 - 1.1e-06 28.1 0.0 0.0036 16.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EDN91957.1 - 1.9e-06 27.5 0.0 4.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EDN91957.1 - 5.2e-06 26.7 0.3 1.5e-05 25.2 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Cys_rich_CWC PF14375.1 EDN91960.1 - 0.42 10.5 11.2 1 9.3 3.4 2.7 2 0 0 2 2 2 0 Cysteine-rich CWC DUF2681 PF10883.3 EDN91960.1 - 7.9 6.7 9.3 25 5.1 6.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-CCHC_2 PF13696.1 EDN91961.1 - 0.012 15.1 10.0 0.029 13.8 0.1 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 EDN91961.1 - 0.016 15.0 2.3 0.016 15.0 1.6 5.0 5 1 0 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN91961.1 - 0.41 10.3 12.7 0.74 9.5 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.3 EDN91961.1 - 1 9.3 27.7 0.074 12.9 1.1 4.5 4 1 1 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EDN91961.1 - 8.8 6.1 19.2 1.2 8.9 0.5 3.9 4 0 0 4 4 4 0 Zinc knuckle NmrA PF05368.8 EDN91963.1 - 1.7e-60 204.2 0.0 2.1e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN91963.1 - 0.042 13.8 0.1 1.1 9.2 0.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding FAD_binding_3 PF01494.14 EDN91964.1 - 7e-74 249.0 0.0 9.1e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EDN91964.1 - 2.2e-08 34.3 0.0 5.6e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN91964.1 - 2.4e-06 26.6 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN91964.1 - 0.001 19.0 0.0 0.014 15.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN91964.1 - 0.0085 16.4 0.0 7.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDN91964.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN91964.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HyaE PF07449.6 EDN91964.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE IF4E PF01652.13 EDN91965.1 - 2.9e-48 163.5 0.0 4.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FMO-like PF00743.14 EDN91966.1 - 5.5e-42 143.6 0.0 6.5e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDN91966.1 - 4.9e-19 69.2 0.0 5.3e-18 65.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN91966.1 - 9.9e-13 47.7 0.1 1.1e-09 37.6 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN91966.1 - 6e-12 45.8 0.0 1.6e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN91966.1 - 3.3e-11 43.1 0.1 5.8e-10 39.1 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 EDN91966.1 - 1.4e-08 34.1 0.1 7.3e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EDN91966.1 - 7.6e-08 32.2 0.1 4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN91966.1 - 3.5e-06 26.1 0.6 0.032 13.1 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN91966.1 - 0.00013 20.6 0.3 0.017 13.5 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EDN91966.1 - 0.0011 19.3 0.1 0.08 13.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDN91966.1 - 0.031 14.3 0.1 0.85 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EDN91966.1 - 0.13 11.2 0.1 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Na_Ca_ex PF01699.19 EDN91968.1 - 0.026 14.1 5.0 0.038 13.5 3.5 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Clr5 PF14420.1 EDN91970.1 - 3.5e-09 36.4 0.3 4.1e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Clr5 domain DUF632 PF04782.7 EDN91970.1 - 0.02 14.0 0.1 0.02 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Ank_2 PF12796.2 EDN91972.1 - 3.2e-17 62.6 0.0 9.9e-17 61.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDN91972.1 - 8.2e-16 56.9 0.0 1.4e-09 37.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EDN91972.1 - 1.3e-14 54.2 1.5 1.3e-07 31.9 0.1 3.5 2 1 2 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN91972.1 - 1.5e-13 50.4 0.0 1.3e-08 34.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN91972.1 - 1.4e-12 46.5 0.2 9.1e-07 28.5 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.7 EDN91972.1 - 1.2e-07 31.5 1.6 1.8e-07 30.9 0.0 2.1 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EDN91972.1 - 1.1e-05 25.5 0.0 4.6e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN91972.1 - 0.00036 20.6 0.0 0.0016 18.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EDN91972.1 - 0.007 16.2 0.1 0.16 11.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDN91972.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EDN91972.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EDN91972.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EDN91972.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EDN91972.1 - 0.037 12.8 0.0 0.077 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EDN91972.1 - 0.13 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PIF1 PF05970.9 EDN91972.1 - 0.14 11.0 0.7 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase Peptidase_A4 PF01828.12 EDN91974.1 - 2.8e-82 274.8 15.0 3.3e-82 274.5 10.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family Myb_DNA-bind_6 PF13921.1 EDN91979.1 - 1.4e-25 89.1 5.8 1.1e-13 51.1 0.3 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN91979.1 - 4.6e-25 87.4 8.4 4.2e-09 36.3 0.9 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain tRNA_U5-meth_tr PF05958.6 EDN91979.1 - 0.08 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MADF_DNA_bdg PF10545.4 EDN91979.1 - 0.1 12.7 8.9 0.69 10.1 0.2 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EphA2_TM PF14575.1 EDN91982.1 - 0.004 17.5 0.2 0.0096 16.2 0.1 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 EDN91982.1 - 0.0078 15.9 0.4 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 WBP-1 PF11669.3 EDN91982.1 - 0.017 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 TMEM51 PF15345.1 EDN91982.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 FAM176 PF14851.1 EDN91982.1 - 0.05 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 FAM176 family PAP_fibrillin PF04755.7 EDN91982.1 - 0.05 13.3 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 PAP_fibrillin Tweety PF04906.8 EDN91982.1 - 0.13 10.6 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 EDN91982.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 EDN91982.1 - 0.43 10.1 3.6 0.76 9.3 2.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 2OG-FeII_Oxy_3 PF13640.1 EDN91984.1 - 4.2e-08 33.6 0.0 8.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EDN91984.1 - 5.3e-06 25.9 0.1 1.3e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_3 PF00933.16 EDN91985.1 - 9e-88 294.0 0.0 1.3e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN91985.1 - 1.2e-58 198.3 0.2 2.8e-58 197.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN91985.1 - 1.1e-20 73.2 0.0 2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 EDN91985.1 - 3e-10 39.5 8.2 8.2e-10 38.1 5.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain VTC PF09359.5 EDN91986.1 - 2.9e-89 298.8 0.2 6.6e-89 297.6 0.1 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EDN91986.1 - 7.3e-16 58.7 33.9 2.6e-10 40.5 4.1 4.5 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EDN91986.1 - 9.4e-12 44.9 1.7 2.2e-11 43.7 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Glu_synthase PF01645.12 EDN91987.1 - 2.1e-160 533.6 0.0 3.2e-160 533.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EDN91987.1 - 2.4e-129 431.1 0.0 3.6e-129 430.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EDN91987.1 - 7.4e-116 386.4 0.0 1.3e-115 385.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EDN91987.1 - 1.5e-68 229.8 3.1 2.9e-68 228.8 2.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EDN91987.1 - 3.1e-22 78.2 0.0 7.9e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EDN91987.1 - 2e-17 63.7 0.1 4.6e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN91987.1 - 3e-10 40.5 0.5 0.00041 20.4 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN91987.1 - 1.7e-09 37.9 0.1 7.4e-06 26.2 0.1 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN91987.1 - 3e-09 36.7 0.1 1.1e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN91987.1 - 2.8e-06 26.4 0.7 1.4e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EDN91987.1 - 2.9e-06 26.6 0.1 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EDN91987.1 - 5.2e-06 25.2 0.2 1.2e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EDN91987.1 - 2.4e-05 23.3 0.2 8.2e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EDN91987.1 - 0.00017 20.7 0.1 0.0012 18.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EDN91987.1 - 0.00024 21.2 1.5 0.16 12.1 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EDN91987.1 - 0.00025 20.8 0.1 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 EDN91987.1 - 0.0018 16.5 0.2 1 7.4 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EDN91987.1 - 0.0021 17.1 0.1 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDN91987.1 - 0.0034 16.5 0.1 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDN91987.1 - 0.0066 16.0 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DJ-1_PfpI PF01965.19 EDN91987.1 - 0.0089 15.4 1.1 0.52 9.7 0.1 2.5 1 1 0 2 2 2 1 DJ-1/PfpI family Shikimate_DH PF01488.15 EDN91987.1 - 0.021 14.9 0.4 7.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EDN91987.1 - 0.025 13.7 0.1 0.08 12.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EDN91987.1 - 0.027 14.2 0.7 1.3 8.8 0.2 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.1 EDN91987.1 - 0.063 13.0 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 1 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 EDN91987.1 - 0.081 13.3 0.1 0.76 10.2 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EDN91987.1 - 0.082 12.3 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.13 EDN91987.1 - 0.11 11.3 0.7 0.4 9.4 0.4 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.7 EDN91987.1 - 0.15 10.9 0.1 0.78 8.5 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EDN91987.1 - 0.32 9.8 3.3 0.17 10.6 0.1 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDN91987.1 - 0.71 9.4 4.0 0.14 11.7 0.1 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Apc15p PF05841.6 EDN91988.1 - 1.8e-20 73.8 7.5 1.8e-20 73.8 5.2 3.4 3 1 0 3 3 3 1 Apc15p protein SNARE PF05739.14 EDN91989.1 - 2e-09 37.0 3.0 2.6e-09 36.6 2.1 1.2 1 0 0 1 1 1 1 SNARE domain Peroxin-13_N PF04088.8 EDN91989.1 - 0.03 14.2 0.1 0.047 13.6 0.1 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF4234 PF14018.1 EDN91989.1 - 0.065 12.9 0.2 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) CHZ PF09649.5 EDN91990.1 - 5.5e-15 54.3 2.6 5.5e-15 54.3 1.8 2.2 2 1 1 3 3 3 1 Histone chaperone domain CHZ A_deaminase PF00962.17 EDN91991.1 - 2.8e-109 365.0 0.0 3.8e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Acetyltransf_1 PF00583.19 EDN91992.1 - 5.8e-09 35.8 0.0 9.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EDN91992.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EDN91992.1 - 0.0039 17.3 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN91992.1 - 0.021 14.5 0.1 0.042 13.6 0.1 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EDN91992.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN91992.1 - 0.044 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDN91992.1 - 0.047 13.5 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Podoplanin PF05808.6 EDN91993.1 - 6.9 6.2 9.3 7.9 6.0 6.5 1.0 1 0 0 1 1 1 0 Podoplanin Tim54 PF11711.3 EDN91994.1 - 4.7 5.6 5.0 6.2 5.3 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ATP-grasp_2 PF08442.5 EDN91995.1 - 9.5e-79 263.4 0.6 1.6e-78 262.7 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EDN91995.1 - 2.3e-26 92.2 1.0 4.5e-26 91.2 0.2 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EDN91995.1 - 2.1e-10 40.1 0.2 4.7e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EDN91995.1 - 0.008 15.7 1.3 0.058 12.9 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EDN91995.1 - 0.014 14.9 0.0 0.27 10.6 0.0 2.7 2 1 1 3 3 3 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 EDN91995.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain AA_permease_2 PF13520.1 EDN91997.1 - 1.1e-55 188.9 51.4 1.2e-55 188.7 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN91997.1 - 5.1e-32 110.8 45.0 6.7e-32 110.4 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease RHD3 PF05879.7 EDN91998.1 - 0 1037.2 0.0 0 1036.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EDN91998.1 - 1.3e-07 30.9 0.1 2.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EDN91998.1 - 1.2e-06 28.3 0.1 3.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EDN91998.1 - 0.00019 21.3 0.1 0.00069 19.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EDN91998.1 - 0.0016 18.4 0.0 0.0059 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EDN91998.1 - 0.0021 18.5 0.1 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EDN91998.1 - 0.097 11.6 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Septin MFS_1 PF07690.11 EDN91999.1 - 2.8e-35 121.6 23.6 2.8e-35 121.6 16.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Y_phosphatase PF00102.22 EDN92000.1 - 9.8e-47 159.2 0.0 3.4e-45 154.2 0.0 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EDN92000.1 - 5.5e-11 42.8 0.0 3.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain GMC_oxred_N PF00732.14 EDN92001.1 - 2.4e-25 89.2 0.1 6.9e-25 87.7 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN92001.1 - 1.3e-17 64.4 0.1 2.4e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN92001.1 - 1.2e-07 30.9 1.4 0.0017 17.2 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN92001.1 - 8.5e-07 28.1 0.8 7.3e-05 21.8 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN92001.1 - 0.00037 20.6 0.3 0.038 14.0 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN92001.1 - 0.0017 18.3 1.2 0.0031 17.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDN92001.1 - 0.002 16.6 0.4 0.0034 15.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Collagen PF01391.13 EDN92001.1 - 0.0021 17.5 4.6 0.0021 17.5 3.2 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.9 EDN92001.1 - 0.0026 17.6 0.6 0.0075 16.1 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN92001.1 - 0.018 15.4 0.4 0.28 11.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN92001.1 - 0.021 13.9 0.1 0.041 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EDN92001.1 - 0.038 13.0 1.3 0.16 11.0 0.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF2977 PF11192.3 EDN92001.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) GIDA PF01134.17 EDN92001.1 - 0.14 10.9 0.3 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EDN92002.1 - 2.3e-126 422.0 2.5 2.9e-126 421.7 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EDN92002.1 - 4.4e-45 152.6 1.0 6.5e-45 152.1 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EDN92002.1 - 3.9e-07 30.1 0.1 0.0013 18.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDN92002.1 - 4.7e-06 25.7 1.3 0.0078 15.1 1.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EDN92002.1 - 3.9e-05 22.8 0.3 0.031 13.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EDN92002.1 - 0.00014 20.8 0.2 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDN92002.1 - 0.013 14.6 0.1 0.013 14.6 0.1 1.8 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EDN92002.1 - 0.045 12.2 2.0 0.11 10.9 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 EDN92002.1 - 0.51 10.3 2.7 1.7 8.6 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Toxin_45 PF15524.1 EDN92003.1 - 0.19 11.8 1.9 0.63 10.2 0.4 2.5 3 0 0 3 3 3 0 Putative toxin 45 T2SI PF02501.12 EDN92003.1 - 2.3 8.2 7.9 0.16 11.9 1.9 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I BCS1_N PF08740.6 EDN92004.1 - 4.3e-47 160.1 3.9 8.3e-47 159.2 2.7 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN92004.1 - 2.5e-16 60.1 0.0 8e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN92004.1 - 0.0012 19.6 0.0 0.0047 17.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDN92004.1 - 0.0023 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EDN92004.1 - 0.018 14.4 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN92004.1 - 0.023 14.4 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN92004.1 - 0.037 14.0 0.2 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 EDN92004.1 - 0.041 13.0 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EDN92004.1 - 0.12 12.2 0.5 0.59 10.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDN92004.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EDN92004.1 - 0.16 11.7 0.1 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Syntaxin-6_N PF09177.6 EDN92005.1 - 8.5e-23 80.5 0.4 1.3e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EDN92005.1 - 7e-11 41.6 5.9 2.9e-09 36.4 1.2 2.5 2 0 0 2 2 2 2 SNARE domain TPR_MLP1_2 PF07926.7 EDN92005.1 - 0.036 13.8 1.1 1 9.1 0.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EDN92005.1 - 0.039 14.1 4.8 2 8.7 0.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EDN92005.1 - 0.054 13.6 1.6 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EDN92005.1 - 0.11 12.2 0.3 15 5.3 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EDN92005.1 - 0.13 12.0 1.7 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EDN92005.1 - 0.2 11.2 4.1 8.6 5.9 1.6 2.1 1 1 1 2 2 2 0 IncA protein B56 PF01603.15 EDN92006.1 - 1.9e-174 580.1 6.8 2.2e-174 579.8 4.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PYC_OADA PF02436.13 EDN92006.1 - 0.036 13.4 0.3 0.22 10.9 0.0 2.3 3 0 0 3 3 3 0 Conserved carboxylase domain Dynamin_N PF00350.18 EDN92006.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Tau95 PF09734.4 EDN92008.1 - 1.8e-65 221.3 0.0 2.4e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit WD40 PF00400.27 EDN92009.1 - 6.9e-14 51.1 1.5 0.14 12.0 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nop10p PF04135.7 EDN92010.1 - 1.6e-20 72.5 0.1 1.9e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EDN92011.1 - 3e-32 110.2 2.1 6.4e-32 109.2 1.5 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EDN92011.1 - 1.6e-05 24.7 5.4 2.5e-05 24.1 3.0 2.0 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EDN92011.1 - 0.012 15.0 0.9 0.012 15.0 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RRM_1 PF00076.17 EDN92012.1 - 2.5e-32 110.3 0.0 2.9e-18 65.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN92012.1 - 1.5e-25 88.9 0.0 1.8e-12 47.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN92012.1 - 3.3e-09 36.4 0.0 7e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_1 PF00054.18 EDN92012.1 - 0.011 15.7 0.0 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain Laminin_G_2 PF02210.19 EDN92012.1 - 0.047 13.7 0.1 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain TPR_11 PF13414.1 EDN92015.1 - 8e-24 83.0 6.0 1.5e-09 37.3 0.5 4.3 2 2 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EDN92015.1 - 5.6e-22 75.8 1.8 2.4e-05 23.8 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EDN92015.1 - 1.5e-21 75.0 2.0 3.4e-06 26.4 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN92015.1 - 4.9e-15 54.6 8.3 0.0017 18.8 0.1 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDN92015.1 - 3.4e-14 51.7 0.8 0.074 13.2 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN92015.1 - 4e-14 52.3 8.1 3.4e-08 33.2 0.3 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDN92015.1 - 1.7e-13 50.6 4.7 0.0093 16.2 0.0 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDN92015.1 - 2.4e-13 50.3 6.2 0.00018 22.0 0.4 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDN92015.1 - 9.9e-13 46.8 2.1 0.0029 17.2 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN92015.1 - 1.3e-11 43.4 0.0 0.0011 18.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDN92015.1 - 9.8e-09 35.2 0.5 0.017 15.2 0.0 4.3 2 2 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN92015.1 - 1.6e-08 34.5 1.5 2e-05 24.6 0.3 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN92015.1 - 6e-07 29.2 1.8 0.098 12.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN92015.1 - 1.7e-05 24.9 2.9 11 6.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN92015.1 - 0.00037 20.3 2.4 0.13 12.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EDN92015.1 - 0.095 12.5 0.1 28 4.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EDN92015.1 - 0.098 12.5 2.3 7.6 6.5 0.2 4.1 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.17 EDN92016.1 - 6.3e-39 131.4 0.9 2e-20 72.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN92016.1 - 5.7e-31 106.3 0.4 1.4e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN92016.1 - 1.7e-17 62.9 0.1 4.4e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN92016.1 - 0.062 13.0 0.9 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 Limkain b1 Mitofilin PF09731.4 EDN92017.1 - 0.00017 20.3 14.9 0.00018 20.3 10.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein NPV_P10 PF05531.7 EDN92017.1 - 0.024 14.8 4.0 0.024 14.8 2.8 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ARGLU PF15346.1 EDN92017.1 - 0.11 12.2 14.7 0.12 12.1 9.9 1.2 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Alb1 PF09135.6 EDN92017.1 - 0.26 11.9 7.2 0.34 11.5 5.0 1.2 1 0 0 1 1 1 0 Alb1 Exonuc_VII_L PF02601.10 EDN92017.1 - 0.32 10.1 10.8 0.35 10.0 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mgr1 PF08602.5 EDN92017.1 - 1.8 7.4 6.1 2.2 7.1 4.2 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1682 PF07946.9 EDN92017.1 - 2.6 6.8 12.0 2.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Scm3 PF10384.4 EDN92017.1 - 2.8 7.4 9.3 5.6 6.5 2.6 2.7 1 1 1 2 2 2 0 Centromere protein Scm3 M PF02370.11 EDN92017.1 - 3.2 8.4 18.2 2.6 8.6 1.4 4.5 3 1 3 6 6 5 0 M protein repeat Atg14 PF10186.4 EDN92017.1 - 5.2 5.9 15.3 5.8 5.7 10.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EDN92017.1 - 8.2 4.7 9.9 8.8 4.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SET PF00856.23 EDN92019.1 - 8.4e-11 42.4 0.1 1.8e-09 38.1 0.1 2.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EDN92019.1 - 9.3e-06 25.4 39.5 0.00014 21.6 8.5 3.5 4 0 0 4 4 4 2 MYND finger DUF641 PF04859.7 EDN92020.1 - 0.016 14.9 0.8 0.072 12.8 0.1 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EDN92020.1 - 0.13 11.8 0.1 0.13 11.8 0.1 3.3 3 1 0 3 3 3 0 IncA protein Fib_alpha PF08702.5 EDN92020.1 - 0.37 10.9 11.4 0.25 11.4 0.6 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RNase_T PF00929.19 EDN92021.1 - 2.7e-25 89.5 0.0 4.6e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RIO1 PF01163.17 EDN92021.1 - 0.15 11.3 0.6 0.62 9.3 0.2 1.9 2 0 0 2 2 2 0 RIO1 family GAF_2 PF13185.1 EDN92023.1 - 0.00022 21.7 0.0 0.00049 20.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EDN92023.1 - 0.0016 18.5 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain ATP-synt_ab PF00006.20 EDN92024.1 - 2.2e-49 167.8 0.0 3.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN92024.1 - 6.5e-28 97.4 0.1 1.7e-27 96.1 0.1 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ANTH PF07651.11 EDN92026.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 ANTH domain Radical_SAM PF04055.16 EDN92027.1 - 8.3e-06 26.0 0.0 1.9e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily LAM_C PF12544.3 EDN92027.1 - 0.00034 20.6 0.2 0.00072 19.6 0.1 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_14 PF13394.1 EDN92027.1 - 0.0038 17.2 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EDN92027.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fe_hyd_lg_C PF02906.9 EDN92027.1 - 0.051 12.8 0.1 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain BNR PF02012.15 EDN92031.1 - 1.9e-08 32.8 33.6 0.52 10.3 0.1 11.5 11 0 0 11 11 11 5 BNR/Asp-box repeat BNR_2 PF13088.1 EDN92031.1 - 7.9e-06 25.3 7.0 0.039 13.2 0.0 5.4 6 1 0 6 6 6 2 BNR repeat-like domain APH PF01636.18 EDN92034.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.3 EDN92035.1 - 1.3e-41 142.7 0.0 6.2e-41 140.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative HTH_26 PF13443.1 EDN92035.1 - 0.17 12.1 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain 5-FTHF_cyc-lig PF01812.15 EDN92036.1 - 9.8e-09 35.2 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family COX6B PF02297.12 EDN92037.1 - 8.5e-22 76.9 4.6 1e-21 76.7 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EDN92037.1 - 0.094 12.7 0.7 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 HATPase_c PF02518.21 EDN92038.1 - 2.8e-27 94.6 0.1 6.6e-27 93.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN92038.1 - 1.2e-19 70.3 0.2 3.2e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PAS_3 PF08447.6 EDN92038.1 - 1.7e-16 60.0 2.7 4.2e-16 58.8 1.9 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EDN92038.1 - 8.3e-12 45.4 0.0 8.1e-11 42.2 0.0 2.6 3 0 0 3 3 3 1 PAS domain HisKA PF00512.20 EDN92038.1 - 2.5e-08 33.7 0.1 6.1e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EDN92038.1 - 1.9e-06 27.6 0.1 8.3e-05 22.3 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EDN92038.1 - 9.1e-05 22.4 0.4 0.00067 19.6 0.1 2.3 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 EDN92038.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M28 PF04389.12 EDN92039.1 - 1.2e-33 116.3 0.0 1.9e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDN92039.1 - 5.4e-17 61.3 0.3 1.2e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EDN92039.1 - 0.011 14.5 0.0 0.062 12.0 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF2533 PF10752.4 EDN92041.1 - 0.015 15.5 0.8 0.028 14.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Glycos_trans_3N PF02885.12 EDN92041.1 - 0.028 14.0 0.1 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Inhibitor_I9 PF05922.11 EDN92041.1 - 0.082 13.4 0.3 0.19 12.3 0.1 1.8 1 1 0 1 1 1 0 Peptidase inhibitor I9 Esterase_phd PF10503.4 EDN92042.1 - 3.8e-22 78.6 0.2 4.7e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EDN92042.1 - 3.4e-10 39.5 0.4 4.8e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN92042.1 - 7.4e-05 22.5 0.2 9.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDN92042.1 - 0.035 13.6 0.2 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.2 EDN92047.1 - 1.3e-35 121.5 8.9 2.9e-12 46.7 0.5 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN92047.1 - 2.1e-22 77.7 11.7 1.7e-07 30.6 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EDN92047.1 - 4.9e-22 77.4 8.4 5.7e-07 29.5 0.1 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN92047.1 - 4.4e-16 58.8 5.3 1.7e-08 34.7 0.3 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN92047.1 - 2.7e-15 54.9 6.5 0.00066 19.6 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat EI24 PF07264.6 EDN92048.1 - 0.00041 19.8 16.0 0.0023 17.3 11.1 2.0 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) NeA_P2 PF12312.3 EDN92049.1 - 0.48 9.6 4.9 0.79 8.9 3.4 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein REV PF00424.13 EDN92049.1 - 0.85 9.5 6.1 1.3 8.9 3.7 1.6 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) zf-CCCH PF00642.19 EDN92051.1 - 0.00024 20.6 2.7 0.00091 18.8 0.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDN92051.1 - 0.17 11.9 7.5 0.64 10.1 3.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SAC3_GANP PF03399.11 EDN92052.1 - 1.2e-24 87.0 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDN92052.1 - 3.4e-19 69.0 0.0 5.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Helicase_C_2 PF13307.1 EDN92053.1 - 8.2e-49 165.7 0.4 3.3e-48 163.8 0.1 2.2 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDN92053.1 - 1.4e-39 135.2 0.0 2.6e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EDN92053.1 - 0.0073 16.1 0.2 3.1 7.6 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN92053.1 - 0.18 11.9 3.1 9.2 6.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain Enterotoxin_ST PF02048.11 EDN92054.1 - 0.084 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Heat-stable enterotoxin ST TBPIP PF07106.8 EDN92055.1 - 4.7e-27 94.5 1.7 7e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EDN92055.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 1.9 2 0 0 2 2 2 1 IncA protein DUF603 PF04645.7 EDN92055.1 - 0.012 15.6 0.3 0.012 15.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF603 DivIC PF04977.10 EDN92055.1 - 0.051 13.0 3.6 5.5 6.5 0.0 2.8 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EDN92055.1 - 0.083 12.8 0.6 0.73 9.7 0.2 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.8 EDN92055.1 - 0.13 12.0 2.9 0.5 10.1 2.0 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3332 PF11810.3 EDN92055.1 - 0.5 10.0 7.4 0.86 9.2 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF641 PF04859.7 EDN92055.1 - 1.9 8.2 6.3 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 EDN92055.1 - 3.8 6.3 5.2 0.68 8.8 0.0 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Rota_VP2 PF05087.7 EDN92055.1 - 3.9 5.2 5.8 4.8 4.9 4.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Sel1 PF08238.7 EDN92056.1 - 8e-08 32.6 31.4 7.4e-06 26.4 0.7 7.2 7 0 0 7 7 7 4 Sel1 repeat TPR_11 PF13414.1 EDN92056.1 - 0.016 14.7 0.2 0.016 14.7 0.2 3.2 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 EDN92056.1 - 0.02 14.4 0.2 0.14 11.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.15 EDN92057.1 - 3.1e-188 626.0 0.0 3.8e-188 625.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.19 EDN92058.1 - 9.8e-149 496.0 0.2 1.1e-148 495.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.9 EDN92059.1 - 2.7e-40 138.4 0.0 3.7e-39 134.6 0.0 2.0 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EDN92059.1 - 1.9e-11 43.8 0.1 6.4e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN92059.1 - 4.4e-06 26.0 0.0 0.00035 19.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EDN92059.1 - 1e-05 24.6 0.0 0.00013 21.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN92059.1 - 0.00044 20.0 0.5 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDN92059.1 - 0.00046 20.3 0.1 0.08 12.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN92059.1 - 0.00074 19.4 0.1 0.49 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN92059.1 - 0.0033 16.5 0.4 0.068 12.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EDN92059.1 - 0.0099 15.3 0.7 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EDN92059.1 - 0.012 15.9 1.0 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 EDN92060.1 - 1.2e-06 27.9 0.0 3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.22 EDN92061.1 - 2.7e-34 118.4 0.0 4.7e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDN92061.1 - 3.2e-33 115.3 11.6 4.6e-33 114.8 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDN92061.1 - 3e-08 34.0 0.0 0.0014 18.6 0.0 2.8 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EDN92061.1 - 1.1e-06 28.0 0.1 0.00067 18.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN92061.1 - 6e-05 23.1 0.0 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN92061.1 - 0.00015 22.5 0.0 0.00028 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN92061.1 - 0.00016 21.5 0.0 0.0021 17.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN92061.1 - 0.00046 20.3 0.0 0.0042 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN92061.1 - 0.00065 20.0 0.0 0.0025 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDN92061.1 - 0.001 19.2 0.0 0.063 13.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EDN92061.1 - 0.0068 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDN92061.1 - 0.008 15.6 0.1 0.024 14.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EDN92061.1 - 0.0096 15.3 0.0 0.026 13.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDN92061.1 - 0.01 15.7 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN92061.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Rad17 PF03215.10 EDN92061.1 - 0.03 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EDN92061.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EDN92061.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EDN92061.1 - 0.062 12.8 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDN92061.1 - 0.069 12.2 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EDN92061.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EDN92061.1 - 0.087 11.3 0.4 1.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EDN92061.1 - 0.092 12.6 0.3 0.71 9.8 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PRK PF00485.13 EDN92061.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TPR_1 PF00515.23 EDN92061.1 - 0.22 11.2 1.0 0.61 9.8 0.5 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat AIM24 PF01987.12 EDN92062.1 - 2.6e-07 30.3 0.0 3.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EDN92062.1 - 0.04 14.3 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) AIM24 PF01987.12 EDN92063.1 - 4.6e-20 71.9 0.0 5.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DDE_1 PF03184.14 EDN92065.1 - 1.6e-16 60.1 0.2 3e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN92065.1 - 2.1e-13 49.5 0.1 4.4e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN92065.1 - 4.7e-10 39.1 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDN92065.1 - 3.2e-05 23.7 0.0 0.0002 21.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN92065.1 - 0.0025 17.5 0.2 0.0059 16.4 0.1 1.6 1 0 0 1 1 1 1 NUMOD1 domain HTH_28 PF13518.1 EDN92065.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EDN92065.1 - 0.0059 15.9 0.4 0.012 14.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.1 EDN92065.1 - 0.0066 16.2 0.7 0.014 15.2 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN92065.1 - 0.016 14.8 2.3 0.018 14.7 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_DeoR PF08220.7 EDN92065.1 - 0.054 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain UPF0175 PF03683.8 EDN92065.1 - 0.075 12.5 0.1 0.26 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_Tnp_ISL3 PF13542.1 EDN92065.1 - 0.086 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 WSC PF01822.14 EDN92066.1 - 1e-14 54.2 8.4 2.1e-14 53.2 5.9 1.5 1 0 0 1 1 1 1 WSC domain Drc1-Sld2 PF11719.3 EDN92073.1 - 3.1e-110 369.2 30.3 3.6e-110 368.9 21.0 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Fig1 PF12351.3 EDN92076.1 - 7e-57 192.2 4.4 9.4e-57 191.8 3.1 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EDN92076.1 - 1.3e-07 31.4 5.7 1.7e-07 31.0 3.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EDN92076.1 - 4e-05 22.6 6.4 5.6e-05 22.1 4.4 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EDN92076.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Oxidored_q3 PF00499.15 EDN92076.1 - 0.54 10.0 11.2 2 8.1 7.0 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2976 PF11190.3 EDN92076.1 - 2.2 7.8 0.0 2.2 7.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF4064 PF13273.1 EDN92076.1 - 4 7.6 14.9 0.17 12.0 0.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 EDN92076.1 - 6.4 6.1 11.9 0.16 11.3 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HTH_Tnp_Tc5 PF03221.11 EDN92079.1 - 5.2e-08 32.5 0.0 8.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN92079.1 - 0.00085 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pec_lyase_C PF00544.14 EDN92080.1 - 1.7e-17 63.6 0.7 3.2e-17 62.6 0.5 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EDN92080.1 - 2e-06 27.6 11.4 6.9e-05 22.6 7.9 2.4 1 1 0 1 1 1 1 Right handed beta helix region Y_phosphatase PF00102.22 EDN92082.1 - 2.6e-44 151.2 0.0 3.6e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EDN92082.1 - 0.00084 19.6 0.0 0.0035 17.5 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EDN92082.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EDN92082.1 - 0.016 15.2 0.0 0.085 12.9 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF2697 PF10906.3 EDN92083.1 - 0.00014 21.7 0.3 0.00037 20.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) p450 PF00067.17 EDN92085.1 - 3.1e-26 91.9 0.0 4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CW_binding_2 PF04122.7 EDN92086.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Mito_carr PF00153.22 EDN92092.1 - 7.4e-59 195.4 7.7 4.2e-22 77.6 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein APG9 PF04109.11 EDN92093.1 - 9.3e-169 561.1 3.4 1.3e-168 560.6 2.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.6 EDN92094.1 - 1.6e-221 736.7 4.9 5.8e-209 695.2 0.9 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 MFS_1 PF07690.11 EDN92096.1 - 1.7e-38 132.2 54.4 1.9e-38 132.1 33.5 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN92096.1 - 1e-06 27.6 10.5 1e-06 27.6 7.3 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter RCR PF12273.3 EDN92096.1 - 1.2 9.6 5.0 11 6.6 0.2 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pyridox_ox_2 PF12900.2 EDN92097.1 - 4.9e-37 126.9 0.0 6.3e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TMEM219 PF14940.1 EDN92098.1 - 0.085 11.9 0.1 0.085 11.9 0.1 1.0 1 0 0 1 1 1 0 Transmembrane 219 Haem_oxygenas_2 PF14518.1 EDN92101.1 - 9.9e-14 51.3 0.1 3.3e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Iron-containing redox enzyme 2OG-FeII_Oxy PF03171.15 EDN92102.1 - 6.1e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN92102.1 - 0.00036 21.0 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_1b PF00579.20 EDN92103.1 - 1.4e-20 73.6 0.0 2.7e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M20 PF01546.23 EDN92104.1 - 6.2e-22 78.0 0.0 8.5e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN92104.1 - 2.3e-07 30.5 0.1 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain VID27 PF08553.5 EDN92107.1 - 0 1145.9 0.2 0 1145.8 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Ribosomal_S17 PF00366.15 EDN92108.1 - 5.5e-07 29.5 0.5 1.9e-06 27.8 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S17 AAA PF00004.24 EDN92109.1 - 3.1e-11 43.5 0.0 6.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDN92109.1 - 4e-06 26.6 0.2 2.1e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EDN92109.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN92109.1 - 0.00016 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN92109.1 - 0.00072 19.5 0.0 0.011 15.6 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EDN92109.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDN92109.1 - 0.0035 16.5 0.7 0.0071 15.5 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN92109.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDN92109.1 - 0.0099 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EDN92109.1 - 0.01 15.5 0.1 0.026 14.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Guanylate_kin PF00625.16 EDN92109.1 - 0.019 14.4 0.0 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_33 PF13671.1 EDN92109.1 - 0.024 14.5 0.1 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EDN92109.1 - 0.039 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDN92109.1 - 0.04 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EDN92109.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDN92109.1 - 0.056 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN92109.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDN92109.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EDN92109.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Glyco_transf_25 PF01755.12 EDN92110.1 - 0.026 14.1 0.0 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Lipoxygenase PF00305.14 EDN92111.1 - 1.1e-60 205.3 1.3 2.5e-60 204.2 0.3 1.9 2 1 0 2 2 2 1 Lipoxygenase NYN PF01936.13 EDN92112.1 - 0.012 15.9 0.0 0.069 13.4 0.0 2.0 1 1 0 1 1 1 0 NYN domain DUF3602 PF12223.3 EDN92113.1 - 0.056 13.8 0.6 0.19 12.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) TC1 PF15063.1 EDN92113.1 - 0.06 12.8 0.5 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Thyroid cancer protein 1 DNA_methylase PF00145.12 EDN92114.1 - 1.3e-36 126.4 0.0 2.9e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EDN92114.1 - 0.0059 16.6 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PPR_2 PF13041.1 EDN92115.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family BA14K PF07886.6 EDN92115.1 - 0.036 13.7 0.2 0.075 12.7 0.2 1.5 1 0 0 1 1 1 0 BA14K-like protein WD40 PF00400.27 EDN92116.1 - 6.1e-13 48.1 7.7 0.0037 17.1 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat GRAM PF02893.15 EDN92117.1 - 2.3e-28 97.4 1.0 2.9e-16 58.7 0.0 3.6 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EDN92117.1 - 1.5e-26 92.8 0.0 3e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EDN92117.1 - 4.3e-15 55.7 1.0 1.8e-14 53.7 0.1 2.7 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EDN92117.1 - 1.3e-06 28.6 0.5 1.3e-06 28.6 0.3 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EDN92117.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EDN92117.1 - 0.00098 19.1 0.1 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EDN92117.1 - 0.0023 16.5 0.0 0.0037 15.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NIF PF03031.13 EDN92118.1 - 1.8e-26 92.6 0.0 4.1e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EDN92118.1 - 2.9e-10 39.8 2.3 4.1e-10 39.3 0.4 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EDN92118.1 - 2.9e-09 36.9 0.1 1.1e-08 35.0 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 EDN92118.1 - 0.00012 21.6 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme GRIM-19 PF06212.7 EDN92119.1 - 1.8e-23 82.6 0.0 2.7e-23 82.1 0.0 1.3 1 1 0 1 1 1 1 GRIM-19 protein dCMP_cyt_deam_1 PF00383.17 EDN92120.1 - 2.7e-13 49.4 0.0 4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EDN92120.1 - 3.1e-07 30.4 0.2 6.7e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EDN92120.1 - 0.023 14.0 0.5 4.6 6.5 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases SNO PF01174.14 EDN92120.1 - 0.058 13.0 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Ank PF00023.25 EDN92122.1 - 2.7e-32 108.9 4.4 7.7e-10 38.0 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 EDN92122.1 - 5.8e-32 109.8 0.2 1.6e-10 41.1 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN92122.1 - 1.5e-26 91.8 4.6 1.4e-07 31.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN92122.1 - 1.3e-20 71.4 1.8 5.3e-06 26.1 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EDN92122.1 - 2e-18 66.3 3.0 1.1e-05 25.8 0.1 5.3 2 1 3 5 5 4 4 Ankyrin repeats (many copies) NACHT PF05729.7 EDN92122.1 - 9.7e-15 54.6 0.1 2.3e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EDN92122.1 - 4.4e-09 36.5 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN92122.1 - 1.3e-05 25.2 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN92122.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EDN92122.1 - 0.018 13.9 0.2 0.018 13.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain GRIP PF01465.15 EDN92122.1 - 0.019 14.4 0.0 0.34 10.4 0.0 2.5 2 0 0 2 2 2 0 GRIP domain PhoH PF02562.11 EDN92122.1 - 0.06 12.5 0.0 0.21 10.8 0.0 2.0 1 1 0 1 1 1 0 PhoH-like protein ZZ PF00569.12 EDN92125.1 - 5.1e-05 22.7 6.3 5.1e-05 22.7 4.3 1.7 2 0 0 2 2 2 1 Zinc finger, ZZ type DUF3435 PF11917.3 EDN92126.1 - 5.5e-68 229.5 0.0 9.2e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) AAA_10 PF12846.2 EDN92126.1 - 0.091 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 EDN92127.1 - 6.2e-08 32.4 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain COG2 PF06148.6 EDN92127.1 - 0.091 12.6 0.3 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CAMP_factor PF07373.6 EDN92127.1 - 0.1 12.1 0.2 0.6 9.5 0.2 2.2 2 1 0 2 2 2 0 CAMP factor (Cfa) WD40 PF00400.27 EDN92128.1 - 4.2e-178 571.6 51.4 1.5e-15 56.3 0.3 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat PD40 PF07676.7 EDN92128.1 - 4e-13 48.7 21.1 15 5.3 0.0 11.3 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 EDN92128.1 - 5e-13 48.7 5.4 4.1 6.3 0.0 9.7 1 1 9 10 10 10 4 Protein of unknown function (DUF1258) DUF3312 PF11768.3 EDN92128.1 - 1.4e-08 33.4 0.0 6.9 4.7 0.0 8.4 2 2 9 11 11 11 2 Protein of unknown function (DUF3312) Me-amine-dh_H PF06433.6 EDN92128.1 - 8.3e-08 31.2 0.0 0.93 8.0 0.0 5.2 2 1 0 5 5 5 3 Methylamine dehydrogenase heavy chain (MADH) NYD-SP28_assoc PF14775.1 EDN92128.1 - 1.7e-06 27.6 5.6 1e+02 2.6 0.0 9.8 11 0 0 11 11 11 0 Sperm tail C-terminal domain ABM PF03992.11 EDN92128.1 - 0.016 15.2 0.0 1.1e+02 2.9 0.0 5.8 8 1 1 9 9 9 0 Antibiotic biosynthesis monooxygenase TFIIIC_delta PF12657.2 EDN92128.1 - 0.034 13.8 18.2 22 4.7 0.1 7.4 2 2 3 6 6 6 0 Transcription factor IIIC subunit delta N-term PLD_C PF12357.3 EDN92128.1 - 0.14 11.7 4.5 1e+02 2.5 0.0 6.7 9 0 0 9 9 9 0 Phospholipase D C terminal L1R_F9L PF02442.12 EDN92131.1 - 0.068 12.6 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses ATG16 PF08614.6 EDN92140.1 - 7e-06 25.9 6.5 1e-05 25.4 4.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EDN92140.1 - 0.0049 16.4 4.3 0.0081 15.7 3.0 1.3 1 0 0 1 1 1 1 IncA protein YgaB PF14182.1 EDN92140.1 - 0.024 14.8 0.9 0.024 14.8 0.6 2.2 1 1 1 2 2 2 0 YgaB-like protein APG6 PF04111.7 EDN92140.1 - 0.029 13.4 5.6 0.036 13.0 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_Maf PF03131.12 EDN92140.1 - 0.063 13.5 3.3 0.098 12.9 2.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Spectrin PF00435.16 EDN92140.1 - 0.064 13.5 4.8 0.078 13.2 2.8 1.5 1 1 0 1 1 1 0 Spectrin repeat GAS PF13851.1 EDN92140.1 - 0.073 12.2 12.4 0.2 10.8 8.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EDN92140.1 - 0.074 11.7 7.7 0.099 11.2 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2663 PF10864.3 EDN92140.1 - 0.079 13.1 0.6 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) AbiH PF14253.1 EDN92140.1 - 0.081 12.5 4.5 0.087 12.4 3.1 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF2702 PF10863.3 EDN92140.1 - 0.087 12.5 7.6 3.4 7.3 5.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2702) Rabaptin PF03528.10 EDN92140.1 - 0.11 12.4 5.1 0.18 11.7 3.6 1.4 1 0 0 1 1 1 0 Rabaptin DUF972 PF06156.8 EDN92140.1 - 0.14 12.5 8.9 0.91 9.8 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EDN92140.1 - 0.15 12.3 14.4 4.9e+02 1.1 10.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EDN92140.1 - 0.16 11.5 5.8 0.1 12.2 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) WXG100 PF06013.7 EDN92140.1 - 0.17 11.8 2.1 17 5.5 0.0 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Rab5-bind PF09311.6 EDN92140.1 - 0.19 11.6 7.0 0.052 13.4 2.1 1.9 1 1 0 2 2 2 0 Rabaptin-like protein DivIC PF04977.10 EDN92140.1 - 0.19 11.2 13.8 0.15 11.5 2.6 3.1 1 1 1 3 3 3 0 Septum formation initiator SlyX PF04102.7 EDN92140.1 - 0.22 11.9 2.7 0.2 12.0 0.5 1.8 2 0 0 2 2 2 0 SlyX Tnp_P_element PF12017.3 EDN92140.1 - 0.23 10.6 4.0 0.16 11.1 1.4 1.6 1 1 1 2 2 2 0 Transposase protein Peptidase_C6 PF00851.13 EDN92140.1 - 0.3 9.6 2.7 0.36 9.4 1.9 1.0 1 0 0 1 1 1 0 Helper component proteinase DUF1319 PF07028.6 EDN92140.1 - 0.33 11.1 5.2 1 9.5 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Atg14 PF10186.4 EDN92140.1 - 0.34 9.8 9.2 0.58 9.0 6.4 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EDN92140.1 - 0.4 10.9 2.7 5.2 7.4 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.13 EDN92140.1 - 0.41 10.3 8.1 2.5 7.8 0.5 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EDN92140.1 - 0.43 10.5 6.0 0.24 11.3 0.3 2.8 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AAA_23 PF13476.1 EDN92140.1 - 0.43 10.8 10.6 0.55 10.5 7.4 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 EDN92140.1 - 0.44 10.3 10.0 0.35 10.7 5.2 1.9 1 1 1 2 2 2 0 Tropomyosin like TBPIP PF07106.8 EDN92140.1 - 0.5 9.8 9.7 0.17 11.4 1.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_CLD_2 PF14197.1 EDN92140.1 - 0.55 10.2 6.4 13 5.7 0.0 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 zf-C4H2 PF10146.4 EDN92140.1 - 0.68 9.9 7.4 2.4 8.1 5.1 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Viral_P18 PF04521.8 EDN92140.1 - 0.74 9.2 5.3 6.6 6.1 1.6 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Nnf1 PF03980.9 EDN92140.1 - 1.9 8.5 8.3 0.6 10.1 0.3 2.9 2 1 2 4 4 4 0 Nnf1 TMF_DNA_bd PF12329.3 EDN92140.1 - 6.3 6.6 13.1 1.5 8.6 5.3 2.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding EST1_DNA_bind PF10373.4 EDN92144.1 - 4.9e-18 65.3 0.1 1.5e-17 63.7 0.1 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF1675 PF07897.6 EDN92151.1 - 0.035 13.9 1.9 0.043 13.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) U79_P34 PF03064.11 EDN92151.1 - 0.037 13.5 1.5 0.042 13.3 1.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CopC PF04234.7 EDN92155.1 - 0.073 13.7 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 CopC domain Cerato-platanin PF07249.7 EDN92156.1 - 6.2e-07 29.4 0.1 1.5e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_18 PF00704.23 EDN92158.1 - 3.1e-83 280.0 4.5 3.1e-83 280.0 3.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 RNase_H PF00075.19 EDN92159.1 - 2.6e-14 53.6 0.0 5.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN92159.1 - 0.0032 17.7 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase AAA PF00004.24 EDN92160.1 - 1.5e-09 38.1 0.0 3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN92160.1 - 6.9e-06 26.8 0.1 1.4e-05 25.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDN92160.1 - 0.02 15.1 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EDN92160.1 - 0.034 13.0 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EDN92160.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IPT PF01745.11 EDN92160.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.11 EDN92160.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Herpes_BMRF2 PF04633.7 EDN92165.1 - 0.061 12.2 0.1 0.07 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein DnaJ PF00226.26 EDN92166.1 - 0.00028 20.5 0.1 0.0015 18.2 0.1 2.4 1 0 0 1 1 1 1 DnaJ domain ZYG-11_interact PF05884.7 EDN92166.1 - 0.18 10.8 4.0 0.85 8.6 3.3 1.6 2 0 0 2 2 2 0 Interactor of ZYG-11 TOM_sub5 PF15178.1 EDN92168.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog THOC7 PF05615.8 EDN92169.1 - 0.047 13.9 0.5 0.062 13.5 0.4 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 Tropomyosin_1 PF12718.2 EDN92171.1 - 0.01 15.6 9.8 0.016 15.0 1.4 2.7 2 1 0 2 2 2 0 Tropomyosin like Syntaxin-18_N PF10496.4 EDN92171.1 - 0.026 14.3 0.1 0.073 12.9 0.1 1.8 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Gln-synt_C PF00120.19 EDN92171.1 - 0.081 12.0 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain Nup54 PF13874.1 EDN92171.1 - 2.9 7.5 11.5 0.12 11.9 1.5 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Uds1 PF15456.1 EDN92171.1 - 6.8 6.7 13.5 68 3.4 9.1 2.2 1 1 0 1 1 1 0 Up-regulated During Septation DUF4633 PF15464.1 EDN92172.1 - 0.014 15.2 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Mto2_bdg PF12808.2 EDN92172.1 - 0.031 14.3 0.2 0.069 13.2 0.2 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.16 EDN92172.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor Microtub_assoc PF07989.6 EDN92172.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.4 1 1 0 1 1 1 0 Microtubule associated bZIP_2 PF07716.10 EDN92172.1 - 0.12 12.1 0.3 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper SRF-TF PF00319.13 EDN92173.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cas_NE0113 PF09623.5 EDN92175.1 - 0.17 11.2 0.1 16 4.8 0.0 2.4 1 1 2 3 3 3 0 CRISPR-associated protein NE0113 (Cas_NE0113) SH3_2 PF07653.12 EDN92175.1 - 4.9 6.7 8.5 74 2.9 0.1 3.3 2 1 0 2 2 2 0 Variant SH3 domain Pkinase PF00069.20 EDN92178.1 - 1.5e-08 34.1 0.1 1.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92178.1 - 0.0031 16.6 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.3 EDN92179.1 - 3.4e-189 629.5 2.4 3.4e-189 629.5 1.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) KAR PF15222.1 EDN92179.1 - 0.17 12.0 1.9 0.44 10.6 0.5 2.2 2 0 0 2 2 2 0 Kidney androgen-regulated Pkinase PF00069.20 EDN92180.1 - 9.2e-14 51.2 0.0 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92180.1 - 2.4e-11 43.2 0.0 3.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2249 PF10006.4 EDN92180.1 - 0.097 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Kinase-like PF14531.1 EDN92180.1 - 0.13 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NAD_binding_6 PF08030.7 EDN92181.1 - 0.00021 21.2 0.0 0.00028 20.8 0.0 1.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DDE_1 PF03184.14 EDN92182.1 - 1.3e-08 34.2 0.6 7.2e-05 22.0 0.5 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease RVT_1 PF00078.22 EDN92184.1 - 1.7e-34 119.0 0.6 3.7e-34 117.9 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN92184.1 - 3e-21 75.2 2.8 3.8e-21 74.8 1.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN92184.1 - 1.4e-14 54.6 0.0 3.6e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN92184.1 - 7.6e-05 22.7 0.4 0.00013 22.0 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EDN92184.1 - 0.015 15.5 0.1 0.063 13.6 0.0 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Pkinase PF00069.20 EDN92185.1 - 3.2e-07 29.7 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EDN92185.1 - 1.6e-05 24.3 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EDN92185.1 - 0.00012 21.2 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN92185.1 - 0.002 17.9 1.2 0.015 15.0 1.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tcp11 PF05794.8 EDN92186.1 - 4.4e-80 269.5 2.4 2.2e-74 250.7 1.1 2.2 2 0 0 2 2 2 2 T-complex protein 11 rpo132 PF12415.3 EDN92189.1 - 0.073 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase HET PF06985.6 EDN92191.1 - 4.9e-18 65.6 5.5 3.8e-16 59.4 3.8 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EDN92191.1 - 5.5e-12 45.1 0.0 8.3e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EDN92191.1 - 5e-08 33.1 0.1 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN92191.1 - 1.7e-07 31.4 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN92191.1 - 5.3e-06 26.1 0.0 9.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.1 EDN92191.1 - 0.00012 21.8 0.0 0.00044 20.0 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN92191.1 - 0.0054 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EDN92191.1 - 0.044 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EDN92191.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.7 EDN92191.1 - 0.26 10.5 0.0 0.47 9.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein TPR_2 PF07719.12 EDN92191.1 - 0.38 10.7 2.7 0.34 10.9 0.2 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF1018 PF06252.7 EDN92192.1 - 0.026 15.0 4.4 0.046 14.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1018) KaiC PF06745.8 EDN92192.1 - 0.076 12.1 0.4 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 KaiC P63C PF10546.4 EDN92192.1 - 0.095 12.6 0.2 0.17 11.8 0.2 1.5 1 1 0 1 1 1 0 P63C domain FAM217 PF15344.1 EDN92192.1 - 0.15 11.5 5.7 0.2 11.1 3.8 1.3 1 1 0 1 1 1 0 FAM217 family T6SS-SciN PF12790.2 EDN92194.1 - 0.42 10.2 2.9 0.98 9.0 1.7 1.9 1 1 0 1 1 1 0 Type VI secretion lipoprotein RXT2_N PF08595.6 EDN92196.1 - 0.0071 16.1 0.2 0.0093 15.7 0.1 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal DnaJ-X PF14308.1 EDN92198.1 - 0.086 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing DUF972 PF06156.8 EDN92199.1 - 0.014 15.7 1.2 0.014 15.7 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EDN92199.1 - 0.046 13.3 0.2 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 EDN92199.1 - 0.078 10.8 0.0 0.078 10.8 0.0 2.1 3 0 0 3 3 3 0 Hsp70 protein CENP-F_leu_zip PF10473.4 EDN92199.1 - 0.087 12.6 1.0 0.17 11.7 0.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-SNARE PF05008.10 EDN92199.1 - 0.11 12.7 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF4164 PF13747.1 EDN92199.1 - 0.15 12.1 2.2 0.3 11.2 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Rootletin PF15035.1 EDN92199.1 - 1.7 8.5 5.5 4.8 7.1 3.8 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RIO1 PF01163.17 EDN92204.1 - 0.037 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF2577 PF10844.3 EDN92204.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) APH PF01636.18 EDN92204.1 - 0.15 11.7 1.9 0.46 10.1 1.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_transpo PF04515.7 EDN92208.1 - 9.9e-11 40.9 14.8 9.9e-11 40.9 10.3 3.2 3 1 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 EDN92209.1 - 1.1e-49 167.9 0.0 5.1e-48 162.5 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN92209.1 - 4.8e-16 59.3 0.0 1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN92209.1 - 1.2e-12 47.4 0.0 4.7e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN92209.1 - 1.2e-07 31.3 0.0 2.9e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN92209.1 - 2.3e-07 30.2 0.0 3.5e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN92209.1 - 0.00019 21.3 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDN92209.1 - 0.0083 16.2 0.0 0.019 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EDN92209.1 - 0.017 14.5 0.1 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EDN92209.1 - 0.019 14.3 0.1 5 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EDN92209.1 - 0.059 12.7 0.1 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EDN92209.1 - 0.15 10.8 0.5 0.28 9.9 0.1 1.5 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 EDN92209.1 - 0.17 11.8 0.5 0.42 10.5 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain UQ_con PF00179.21 EDN92210.1 - 3.1e-17 62.2 0.0 3.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 EDN92211.1 - 7.4e-10 38.4 0.0 9.9e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF59 PF01883.14 EDN92211.1 - 0.078 12.9 0.2 0.99 9.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF59 SUI1 PF01253.17 EDN92212.1 - 1.4e-23 82.4 0.7 3.4e-23 81.2 0.4 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 TnpV PF14198.1 EDN92212.1 - 0.017 14.9 0.6 0.017 14.9 0.4 1.6 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Muted PF14942.1 EDN92212.1 - 0.037 13.9 0.7 0.072 12.9 0.5 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Nbl1_Borealin_N PF10444.4 EDN92213.1 - 1.3e-22 78.8 1.6 2.1e-22 78.2 1.1 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EDN92214.1 - 9.1e-15 55.1 0.1 9.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EDN92214.1 - 7.8e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EDN92214.1 - 2.4e-06 27.4 0.3 3.4e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EDN92214.1 - 0.0012 18.2 1.1 0.0034 16.8 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Sybindin PF04099.7 EDN92215.1 - 6.8e-48 162.0 0.0 1.1e-46 158.1 0.0 2.0 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDN92215.1 - 2.3e-08 33.9 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.11 EDN92216.1 - 2.1e-27 95.4 0.8 2.6e-27 95.1 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 EphA2_TM PF14575.1 EDN92217.1 - 0.0017 18.7 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3147 PF11345.3 EDN92217.1 - 0.006 16.5 0.3 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) Adeno_E3_CR2 PF02439.10 EDN92217.1 - 0.015 14.8 0.6 0.031 13.8 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EDN92217.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Protoglobin PF11563.3 EDN92218.1 - 4.4e-57 192.1 0.1 5.2e-57 191.9 0.1 1.1 1 0 0 1 1 1 1 Protoglobin DUF3734 PF12536.3 EDN92218.1 - 0.077 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Patatin phospholipase Peptidase_M43 PF05572.8 EDN92220.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 EDN92220.1 - 3.3e-05 23.4 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EDN92220.1 - 0.0002 21.4 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EDN92220.1 - 0.00069 19.6 0.0 0.00094 19.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EDN92220.1 - 0.0015 18.3 1.5 0.0035 17.0 1.1 1.8 1 1 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.11 EDN92220.1 - 0.0056 16.3 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.3 EDN92220.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 EDN92220.1 - 0.013 14.4 0.3 0.022 13.6 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EDN92220.1 - 0.042 14.3 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EDN92220.1 - 0.17 11.2 0.1 0.38 10.1 0.1 1.6 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) 3Beta_HSD PF01073.14 EDN92221.1 - 9.9e-61 204.8 0.0 1.3e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN92221.1 - 2.2e-30 105.8 0.1 8.1e-30 103.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN92221.1 - 8.6e-16 57.6 0.2 1.1e-13 50.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EDN92221.1 - 1.1e-10 40.9 0.0 1.3e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDN92221.1 - 2.9e-09 37.2 0.0 6.4e-09 36.0 0.0 1.6 2 1 1 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDN92221.1 - 9.1e-08 31.3 0.0 9.7e-07 27.9 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDN92221.1 - 2e-05 24.6 0.6 4.4e-05 23.4 0.1 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDN92221.1 - 0.00088 18.9 0.2 0.0026 17.4 0.1 1.8 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 EDN92221.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EDN92221.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_trans_4_2 PF13477.1 EDN92221.1 - 0.085 12.6 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like NAD_binding_3 PF03447.11 EDN92221.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pkinase PF00069.20 EDN92222.1 - 3.2e-60 203.4 0.0 7.3e-39 133.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92222.1 - 4.8e-26 91.3 0.0 1.2e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EDN92222.1 - 1.6e-13 50.6 0.2 3.1e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EDN92222.1 - 2.1e-07 30.1 0.0 2.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN92222.1 - 1.2e-05 25.1 0.0 0.0062 16.2 0.1 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 EDN92222.1 - 0.0056 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EDN92222.1 - 0.03 13.4 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EDN92222.1 - 0.075 11.8 0.2 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF3535 PF12054.3 EDN92226.1 - 0.19 10.3 4.2 0.3 9.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Ctr PF04145.10 EDN92226.1 - 2.8 8.0 0.0 2.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Ctr copper transporter family SR-25 PF10500.4 EDN92227.1 - 0.77 9.1 6.0 0.81 9.1 4.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pol_alpha_B_N PF08418.5 EDN92227.1 - 1.1 8.6 4.1 1.4 8.4 2.8 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MFS_1 PF07690.11 EDN92229.1 - 3.3e-38 131.3 25.4 9e-38 129.8 17.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EDN92230.1 - 1.3e-28 100.4 0.0 5.6e-28 98.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN92230.1 - 1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN92230.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN92230.1 - 8.1e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EDN92230.1 - 0.0064 15.3 0.1 0.019 13.7 0.1 1.7 2 0 0 2 2 2 1 Chlorophyllase Chlorophyllase2 PF12740.2 EDN92230.1 - 0.027 13.3 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Cyclase PF04199.8 EDN92234.1 - 2.4e-16 59.9 0.0 3.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase bZIP_1 PF00170.16 EDN92235.1 - 0.00021 21.1 9.7 0.00049 20.0 6.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EDN92235.1 - 0.069 13.1 0.7 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 EDN92235.1 - 0.099 12.9 0.6 0.19 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EDN92235.1 - 0.57 10.5 10.7 0.1 12.9 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 EDN92235.1 - 1 9.6 10.0 1.7 8.9 6.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EDN92235.1 - 4.1 7.2 15.6 46 3.9 9.9 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Dscam_C PF12355.3 EDN92235.1 - 5.6 7.2 10.2 0.8 9.9 3.6 2.1 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal Acyltransferase PF01553.16 EDN92236.1 - 3e-06 26.7 0.1 0.0001 21.7 0.0 2.2 1 1 1 2 2 2 2 Acyltransferase DUF3027 PF11228.3 EDN92236.1 - 0.094 12.3 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Rab5ip PF07019.7 EDN92238.1 - 0.094 12.8 0.1 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Consortin_C PF15281.1 EDN92239.1 - 0.084 12.3 0.5 0.084 12.3 0.4 1.0 1 0 0 1 1 1 0 Consortin C-terminus DUF3317 PF11779.3 EDN92239.1 - 0.13 11.6 0.5 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) SecE PF00584.15 EDN92239.1 - 0.49 10.0 2.2 0.54 9.8 1.5 1.2 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Tad PF13400.1 EDN92239.1 - 1.3 9.1 3.9 1.5 8.9 2.7 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like RELT PF12606.3 EDN92239.1 - 3.3 6.9 6.8 4 6.6 4.7 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 FAD_binding_2 PF00890.19 EDN92240.1 - 3.2e-59 200.8 0.3 3.9e-59 200.5 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN92240.1 - 1.1e-06 28.6 0.0 0.029 14.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN92240.1 - 1.5e-06 28.1 0.0 3.9e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDN92240.1 - 0.00079 17.9 1.9 0.51 8.7 0.4 2.7 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 EDN92240.1 - 0.00093 18.9 0.1 0.23 11.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDN92240.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN92240.1 - 0.0054 15.8 1.3 0.32 10.0 0.2 2.4 2 0 0 2 2 2 1 Thi4 family Strep_67kDa_ant PF06100.6 EDN92240.1 - 0.016 13.5 0.0 0.022 13.1 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_3 PF01494.14 EDN92240.1 - 0.056 12.5 0.4 0.091 11.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EDN92240.1 - 0.056 12.3 1.3 0.091 11.6 0.9 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN92240.1 - 0.2 10.5 0.3 0.36 9.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Cutinase PF01083.17 EDN92241.1 - 9.1e-54 181.8 7.7 1.2e-53 181.5 5.3 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 EDN92241.1 - 2.1e-12 46.4 15.4 2.1e-12 46.4 10.7 4.0 4 1 0 4 4 4 1 Fungal cellulose binding domain PE-PPE PF08237.6 EDN92241.1 - 0.0001 21.8 0.1 0.00022 20.7 0.1 1.5 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EDN92241.1 - 0.062 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN92241.1 - 0.068 13.0 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EDN92242.1 - 1.1e-09 37.9 8.7 1.8e-09 37.3 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN92242.1 - 2.8e-08 32.9 0.0 4.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.7 EDN92242.1 - 0.015 14.9 0.6 0.061 13.1 0.4 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Dicty_CAR PF05462.6 EDN92250.1 - 1.8e-06 27.0 12.8 2.5e-06 26.6 8.9 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EDN92250.1 - 2.6e-05 23.8 16.3 5e-05 22.9 11.3 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EDN92250.1 - 2.9e-05 23.3 5.0 3.4e-05 23.1 3.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Trp_syntA PF00290.15 EDN92251.1 - 2.1e-92 308.3 0.0 3.1e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EDN92251.1 - 2.9e-44 151.5 0.6 5e-44 150.7 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BtpA PF03437.10 EDN92251.1 - 0.012 14.8 0.2 0.029 13.6 0.1 1.6 1 0 0 1 1 1 0 BtpA family DUF1674 PF07896.7 EDN92252.1 - 1.7e-17 63.3 3.0 3.8e-17 62.2 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) MFS_1 PF07690.11 EDN92254.1 - 1.9e-18 66.3 32.0 4.9e-10 38.6 10.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN92254.1 - 8e-15 54.3 20.4 1.5e-14 53.4 14.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter PMBR PF09373.5 EDN92254.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein-binding repeat Glyco_hydro_31 PF01055.21 EDN92255.1 - 4.9e-117 391.4 3.0 8.4e-117 390.6 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN92255.1 - 0.00021 21.0 1.1 0.0015 18.3 0.1 2.9 3 1 0 3 3 3 1 Galactose mutarotase-like FAD_binding_3 PF01494.14 EDN92256.1 - 1.8e-50 171.9 0.0 2.5e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN92256.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN92256.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EDN92256.1 - 0.06 12.2 0.3 0.099 11.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN92256.1 - 0.12 12.4 1.4 0.32 11.0 1.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN92256.1 - 0.12 11.1 1.1 0.15 10.8 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L1 PF00687.16 EDN92257.1 - 0.091 12.0 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family MFS_1 PF07690.11 EDN92260.1 - 3.1e-24 85.3 72.0 4.2e-20 71.7 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MYT1 PF08474.6 EDN92261.1 - 0.19 11.1 1.3 0.3 10.5 0.9 1.3 1 0 0 1 1 1 0 Myelin transcription factor 1 Det1 PF09737.4 EDN92263.1 - 0.55 8.9 3.8 0.91 8.2 2.6 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 PGBA_C PF15437.1 EDN92263.1 - 2.5 8.2 7.4 0.24 11.5 0.9 2.5 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Toxin_7 PF05980.7 EDN92265.1 - 3.8e-06 26.8 12.8 0.0016 18.4 0.8 2.4 2 0 0 2 2 2 2 Toxin 7 UPF0506 PF11703.3 EDN92265.1 - 0.048 13.6 14.2 2.9 7.9 5.0 2.6 1 1 1 2 2 2 0 UPF0506 Antifungal_pept PF11410.3 EDN92265.1 - 0.65 10.1 14.9 1.3 9.1 3.8 2.3 2 0 0 2 2 2 0 Antifungal peptide NIP_1 PF08995.5 EDN92265.1 - 0.93 9.7 12.0 0.21 11.7 4.9 2.0 1 1 1 2 2 2 0 Necrosis inducing protein-1 Bestrophin PF01062.16 EDN92269.1 - 5.6e-50 169.9 0.4 2.3e-48 164.6 0.3 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Abhydrolase_3 PF07859.8 EDN92270.1 - 1e-38 133.0 0.0 1.1e-25 90.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold BTB_2 PF02214.17 EDN92271.1 - 1.3e-05 25.3 0.1 2.5e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_15 PF00723.16 EDN92272.1 - 9.3e-93 311.2 0.1 1.1e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 p450 PF00067.17 EDN92273.1 - 2.2e-59 201.1 0.0 3.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1_like PF12832.2 EDN92273.1 - 0.00029 20.5 1.8 0.2 11.4 0.4 2.5 2 0 0 2 2 2 2 MFS_1 like family IDO PF01231.13 EDN92274.1 - 3.7e-08 32.2 1.0 2.1e-07 29.7 0.7 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DHC PF09626.5 EDN92274.1 - 0.13 12.9 1.7 1 10.0 0.1 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c Ribosomal_L28 PF00830.14 EDN92276.1 - 1.3e-20 72.9 1.7 2.1e-20 72.2 1.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family DUF668 PF05003.7 EDN92276.1 - 0.039 14.1 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) PKD_channel PF08016.7 EDN92278.1 - 5.7e-06 25.0 21.5 7.7e-05 21.2 14.9 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EDN92278.1 - 0.00097 18.4 24.2 0.13 11.4 16.8 2.4 1 1 0 1 1 1 1 Ion transport protein DUF3960 PF13142.1 EDN92278.1 - 0.83 9.4 6.6 59 3.5 3.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3960) Atrophin-1 PF03154.10 EDN92278.1 - 3.2 5.7 14.6 4.3 5.3 10.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Hox9_act PF04617.8 EDN92278.1 - 3.8 7.6 6.3 6.4 6.8 4.3 1.3 1 0 0 1 1 1 0 Hox9 activation region Vfa1 PF08432.5 EDN92278.1 - 6.5 6.7 15.4 11 5.9 10.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PGG PF13962.1 EDN92279.1 - 0.65 9.6 7.4 1.1 8.9 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function TMEM52 PF14979.1 EDN92279.1 - 1.1 9.1 3.0 2 8.3 0.3 2.2 2 0 0 2 2 2 0 Transmembrane 52 adh_short PF00106.20 EDN92281.1 - 4.3e-17 62.5 0.0 1.2e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN92281.1 - 1.6e-06 28.0 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN92281.1 - 0.0001 21.9 0.4 0.00065 19.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EDN92281.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDN92281.1 - 0.0027 17.3 0.3 0.039 13.6 0.2 2.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EDN92281.1 - 0.051 12.6 0.2 0.53 9.3 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EDN92281.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Hydrolase PF00702.21 EDN92282.1 - 4.8e-21 76.1 0.0 3e-20 73.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN92282.1 - 6.3e-20 72.1 0.0 1.4e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN92282.1 - 2.1e-19 69.4 0.0 1.1e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EDN92282.1 - 0.0006 19.7 0.9 0.0014 18.4 0.0 2.1 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN92282.1 - 0.0028 17.2 0.1 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Xan_ur_permease PF00860.15 EDN92283.1 - 6.2e-23 80.9 33.7 2.7e-22 78.7 21.9 2.7 2 1 0 2 2 2 1 Permease family TAT_signal PF10518.4 EDN92283.1 - 0.73 9.9 3.4 1 9.5 0.1 3.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence SUI1 PF01253.17 EDN92285.1 - 8e-30 102.4 0.5 1.4e-29 101.6 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 NESP55 PF06390.7 EDN92285.1 - 0.067 12.5 1.9 0.097 12.0 1.0 1.4 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Kinetocho_Slk19 PF12709.2 EDN92286.1 - 3.4e-19 68.6 3.1 3.4e-19 68.6 2.1 4.6 4 1 1 5 5 5 2 Central kinetochore-associated NYD-SP28_assoc PF14775.1 EDN92286.1 - 0.053 13.2 2.2 1.5 8.5 0.1 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Fmp27_SW PF10305.4 EDN92286.1 - 0.26 11.7 2.4 0.29 11.5 0.2 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Peptidase_S64 PF08192.6 EDN92286.1 - 0.26 9.5 6.5 0.51 8.6 4.5 1.4 1 0 0 1 1 1 0 Peptidase family S64 FlaC_arch PF05377.6 EDN92286.1 - 0.72 9.7 19.6 0.12 12.2 1.3 5.2 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Ufd2P_core PF10408.4 EDN92286.1 - 1.5 6.9 3.8 3.1 5.9 2.6 1.4 1 0 0 1 1 1 0 Ubiquitin elongating factor core IncA PF04156.9 EDN92286.1 - 1.9 8.0 27.6 0.71 9.4 5.5 2.6 2 1 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EDN92286.1 - 2 8.5 13.7 0.44 10.6 2.8 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PTCB-BRCT PF12738.2 EDN92287.1 - 0.00047 19.9 0.3 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EDN92287.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Speriolin_C PF15059.1 EDN92290.1 - 0.05 13.6 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Speriolin C-terminus KilA-N PF04383.8 EDN92293.1 - 0.00033 20.2 0.0 0.0045 16.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Pkinase PF00069.20 EDN92294.1 - 3.3e-21 75.6 0.0 2.7e-20 72.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92294.1 - 1.1e-09 37.7 0.0 2.3e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EDN92294.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3113 PF11310.3 EDN92295.1 - 0.17 11.6 1.2 0.31 10.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Ku PF02735.11 EDN92299.1 - 0.066 12.5 0.0 0.074 12.4 0.0 1.0 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Oxidored_q6 PF01058.17 EDN92302.1 - 5e-22 77.9 0.0 7.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit CTP_transf_2 PF01467.21 EDN92303.1 - 1e-07 32.1 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Herpes_LMP1 PF05297.6 EDN92303.1 - 2 7.2 3.4 2.9 6.7 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PP2C PF00481.16 EDN92304.1 - 2.3e-82 276.2 0.0 3.4e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EDN92304.1 - 0.004 16.6 0.0 0.0074 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Me-amine-dh_H PF06433.6 EDN92306.1 - 0.094 11.3 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Hamartin PF04388.7 EDN92307.1 - 0.51 8.9 4.5 0.66 8.5 3.1 1.2 1 0 0 1 1 1 0 Hamartin protein Aldedh PF00171.17 EDN92308.1 - 1e-11 43.8 10.5 2.2e-08 32.9 4.5 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Rep_fac-A_C PF08646.5 EDN92310.1 - 1.3e-54 183.9 8.9 3.4e-53 179.2 3.8 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EDN92310.1 - 8.6e-24 83.2 0.1 1.8e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EDN92310.1 - 1.3e-16 60.1 0.0 7.2e-12 44.9 0.0 3.6 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain zf-like PF04071.7 EDN92310.1 - 0.0088 15.7 1.2 0.023 14.4 0.8 1.6 1 0 0 1 1 1 1 Cysteine-rich small domain DLH PF01738.13 EDN92311.1 - 1.6e-17 63.5 0.0 3e-16 59.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDN92311.1 - 5.7e-08 32.6 0.0 8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN92311.1 - 0.085 12.3 0.1 4.7 6.6 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Sedlin_N PF04628.8 EDN92312.1 - 1.1e-19 70.5 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EDN92312.1 - 0.15 11.7 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Acyl_transf_1 PF00698.16 EDN92313.1 - 4.6e-19 68.8 0.0 5.5e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain ALAD PF00490.16 EDN92314.1 - 4.4e-117 390.6 0.0 5.3e-117 390.3 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase SET PF00856.23 EDN92318.1 - 0.0036 17.6 0.1 0.007 16.6 0.1 1.5 1 0 0 1 1 1 1 SET domain 6PGD PF00393.14 EDN92319.1 - 1.5e-32 113.0 0.1 2.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDN92319.1 - 1.2e-11 44.6 0.0 2.2e-09 37.3 0.1 2.3 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EDN92319.1 - 0.0033 17.4 0.1 0.0083 16.1 0.0 1.9 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase LIM_bind PF01803.11 EDN92320.1 - 1e-82 276.8 0.0 1e-82 276.8 0.0 5.6 2 1 3 5 5 5 1 LIM-domain binding protein AMP-binding PF00501.23 EDN92322.1 - 9.7e-73 244.9 0.0 1.4e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN92322.1 - 1.5e-65 220.5 0.0 2.4e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EDN92322.1 - 6.6e-12 45.3 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN92322.1 - 1.1e-11 44.7 0.0 2.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EDN92322.1 - 1.3e-09 37.2 0.0 2.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EDN92322.1 - 8.5e-06 26.6 0.0 4.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EDN92322.1 - 0.0004 20.4 0.1 0.43 10.5 0.0 2.7 3 0 0 3 3 3 2 NADH(P)-binding adh_short PF00106.20 EDN92325.1 - 4.4e-27 95.0 0.0 6.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN92325.1 - 2.8e-20 73.1 0.0 3.5e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN92325.1 - 2.3e-13 50.2 0.0 3.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDN92325.1 - 0.0033 17.1 0.1 0.0076 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Vps39_1 PF10366.4 EDN92326.1 - 2.3e-33 114.4 0.0 6.2e-32 109.8 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EDN92326.1 - 3.5e-31 107.6 0.0 4.7e-30 103.9 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EDN92326.1 - 2.1e-18 66.7 0.0 2.1e-17 63.4 0.0 2.1 1 1 0 1 1 1 1 CNH domain TPR_16 PF13432.1 EDN92326.1 - 0.0047 17.5 0.5 2.1 9.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN92326.1 - 0.16 11.6 1.1 38 4.0 0.1 3.5 3 0 0 3 3 3 0 TPR repeat Clathrin PF00637.15 EDN92326.1 - 0.27 10.8 3.9 0.53 9.8 0.2 2.9 2 2 0 2 2 2 0 Region in Clathrin and VPS Apc3 PF12895.2 EDN92326.1 - 0.44 10.7 2.6 8 6.6 0.1 3.4 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 HbrB PF08539.6 EDN92328.1 - 8.8e-09 35.3 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 HbrB-like PLDc PF00614.17 EDN92330.1 - 1.1e-12 47.3 3.9 1.1e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EDN92330.1 - 4.7e-12 45.7 0.1 2.6e-05 23.9 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain HlyIII PF03006.15 EDN92331.1 - 0.14 11.5 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 Haemolysin-III related Ank_2 PF12796.2 EDN92332.1 - 1.5e-14 54.0 0.0 1.1e-05 25.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN92332.1 - 1.9e-14 53.6 0.5 1.8e-08 34.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN92332.1 - 1.8e-11 43.1 0.7 3.6e-05 23.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EDN92332.1 - 6.3e-10 38.3 0.1 0.011 15.9 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EDN92332.1 - 1.9e-09 37.4 0.4 0.0012 19.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EDN92332.1 - 0.00069 19.2 1.4 0.006 16.2 0.2 2.6 2 1 0 2 2 2 1 KilA-N domain DUF641 PF04859.7 EDN92332.1 - 0.41 10.4 5.8 0.73 9.5 0.1 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 EDN92332.1 - 1.4 7.3 8.2 2 6.7 5.7 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.1 EDN92332.1 - 3.1 6.6 11.6 8.5 5.2 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Complex1_LYR PF05347.10 EDN92333.1 - 0.0014 18.3 0.6 0.0089 15.8 0.0 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN92333.1 - 0.0024 18.0 0.8 0.0074 16.4 0.1 2.2 2 0 0 2 2 2 1 Complex1_LYR-like AA_permease_2 PF13520.1 EDN92338.1 - 4.6e-29 101.2 49.2 2.4e-23 82.3 22.3 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN92338.1 - 2.2e-08 32.8 24.8 2.2e-08 32.8 17.2 2.1 1 1 1 2 2 2 1 Amino acid permease Methyltransf_23 PF13489.1 EDN92339.1 - 1.6e-12 47.4 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN92339.1 - 4.6e-07 30.2 0.0 7.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN92339.1 - 1.9e-06 27.5 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN92339.1 - 0.00012 22.6 0.0 0.0002 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDN92339.1 - 0.00031 20.3 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EDN92339.1 - 0.00063 18.8 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.10 EDN92339.1 - 0.0014 17.8 0.1 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.7 EDN92339.1 - 0.0018 18.7 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN92339.1 - 0.0094 16.2 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN92339.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EDN92339.1 - 0.14 11.5 0.0 0.47 9.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MAPEG PF01124.13 EDN92341.1 - 4.2e-17 61.9 3.1 2.5e-16 59.4 2.2 1.8 1 1 0 1 1 1 1 MAPEG family IBR PF01485.16 EDN92342.1 - 3.3e-05 23.6 5.0 3.3e-05 23.6 3.4 2.9 1 1 1 2 2 2 1 IBR domain RRN7 PF11781.3 EDN92342.1 - 0.14 11.6 3.5 2.3 7.8 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Thiolase_N PF00108.18 EDN92344.1 - 7.7e-70 234.8 0.2 1.3e-69 234.1 0.2 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN92344.1 - 1.6e-40 137.3 0.5 3.5e-40 136.2 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN92344.1 - 0.088 12.2 1.1 0.16 11.4 0.4 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Cellulase PF00150.13 EDN92345.1 - 7e-16 58.2 11.7 1.1e-15 57.5 8.1 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EDN92345.1 - 6.2e-06 25.3 0.1 1.9e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_10 PF00331.15 EDN92345.1 - 0.0018 17.3 0.1 0.022 13.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EDN92345.1 - 0.049 14.0 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Sugar-binding cellulase-like DIM1 PF02966.11 EDN92346.1 - 2.6e-67 224.3 0.5 2.9e-67 224.2 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 GST_N_3 PF13417.1 EDN92347.1 - 1e-11 44.8 0.1 2.1e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN92347.1 - 1.4e-06 28.1 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDN92347.1 - 0.00034 21.0 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN92347.1 - 0.00041 20.1 0.0 0.00059 19.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN92347.1 - 0.00061 19.7 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 EDN92350.1 - 5.8e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDN92350.1 - 6.5e-06 25.6 0.0 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EDN92350.1 - 1.1e-05 25.7 0.0 2.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF1961 PF09224.6 EDN92350.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Ank_2 PF12796.2 EDN92352.1 - 3.8e-08 33.5 0.0 1.5e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN92352.1 - 1.1e-05 25.4 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EDN92352.1 - 9.6e-05 22.0 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EDN92352.1 - 0.0002 21.7 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN92352.1 - 0.0032 17.5 0.0 1.1 9.7 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat HATPase_c PF02518.21 EDN92353.1 - 2.9e-11 43.0 0.0 2.9e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3D PF06725.6 EDN92354.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 3D domain PEP_mutase PF13714.1 EDN92355.1 - 7.4e-45 153.0 0.1 8.7e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EDN92355.1 - 1.1e-23 83.2 0.3 1.6e-23 82.7 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.6 EDN92356.1 - 2.1e-39 134.9 11.8 2.5e-39 134.6 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF161 PF02588.10 EDN92356.1 - 2.6 8.4 7.5 4.6 7.6 5.2 1.7 1 1 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DUF663 PF04950.7 EDN92357.1 - 6.7e-88 294.4 0.1 6.7e-88 294.4 0.1 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDN92357.1 - 1.2e-27 95.2 0.0 6.5e-27 92.8 0.0 2.3 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 EDN92357.1 - 8.2e-06 25.9 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 EDN92357.1 - 1.5e-05 24.4 0.0 0.0082 15.5 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EDN92357.1 - 1.9e-05 24.8 0.0 5.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN92357.1 - 9.8e-05 22.0 0.0 0.00027 20.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EDN92357.1 - 0.00019 22.2 0.0 0.00019 22.2 0.0 4.3 3 1 1 4 4 2 1 AAA domain PduV-EutP PF10662.4 EDN92357.1 - 0.00041 19.8 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDN92357.1 - 0.00051 20.5 0.0 0.0019 18.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA PF00004.24 EDN92357.1 - 0.00053 20.1 0.1 0.0014 18.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN92357.1 - 0.00079 18.8 0.1 0.0026 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDN92357.1 - 0.00079 19.3 0.0 0.0027 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN92357.1 - 0.0012 18.5 0.1 0.0031 17.2 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 EDN92357.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 4.8 4 2 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.18 EDN92357.1 - 0.0018 18.2 0.0 0.0049 16.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN92357.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EDN92357.1 - 0.0031 17.8 1.6 0.0057 16.9 0.0 2.3 3 0 0 3 3 1 1 ABC transporter AAA_14 PF13173.1 EDN92357.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDN92357.1 - 0.005 16.5 0.3 0.016 14.8 0.2 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EDN92357.1 - 0.0059 15.4 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 EDN92357.1 - 0.0073 15.9 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN92357.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EDN92357.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EDN92357.1 - 0.017 14.8 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EDN92357.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EDN92357.1 - 0.044 13.4 0.6 0.17 11.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EDN92357.1 - 0.064 11.9 0.3 0.25 9.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 EDN92357.1 - 2.3 8.0 0.0 2.3 8.0 0.0 3.6 3 1 1 4 4 3 0 AAA domain ADH_zinc_N PF00107.21 EDN92358.1 - 1.1e-21 76.7 0.1 1.8e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN92358.1 - 6e-09 36.8 0.0 1.1e-08 35.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN92358.1 - 0.00031 20.4 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain IDO PF01231.13 EDN92359.1 - 1.1e-158 528.1 0.0 1.3e-158 527.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EDN92359.1 - 0.13 10.7 0.1 0.74 8.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 EDN92360.1 - 1.1e-13 50.7 0.0 2.2e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN92360.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_28 PF00295.12 EDN92366.1 - 6.1e-24 84.5 1.4 8.1e-24 84.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.17 EDN92370.1 - 2.3e-37 128.6 0.0 2.7e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UDPG_MGDP_dh_C PF03720.10 EDN92375.1 - 7.6e-06 26.0 0.0 0.022 14.8 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Binary_toxB PF03495.9 EDN92378.1 - 0.00096 17.8 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA Git3 PF11710.3 EDN92380.1 - 7.5e-75 250.9 16.1 7.5e-75 250.9 11.2 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EDN92380.1 - 1.2e-28 98.6 0.6 1.2e-28 98.6 0.4 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3608 PF12257.3 EDN92381.1 - 1.7e-72 243.7 0.0 3e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EDN92381.1 - 7.4e-32 108.9 0.2 1.6e-31 107.8 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Npa1 PF11707.3 EDN92382.1 - 1e-97 327.1 0.0 1.7e-97 326.4 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HEAT PF02985.17 EDN92382.1 - 0.039 14.0 0.2 11 6.3 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Creb_binding PF09030.5 EDN92382.1 - 0.063 13.4 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 Creb binding Sec1 PF00995.18 EDN92384.1 - 5.5e-117 391.7 0.0 6.1e-96 322.2 0.0 2.0 1 1 1 2 2 2 2 Sec1 family BTB PF00651.26 EDN92385.1 - 6.6e-14 51.8 0.0 1.8e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.1 EDN92385.1 - 0.064 12.9 0.2 6 6.5 0.0 3.3 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.20 EDN92388.1 - 5.4e-13 49.1 0.0 1.6e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDN92388.1 - 5.3e-06 26.2 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN92388.1 - 0.00052 19.5 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDN92388.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDN92388.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN92388.1 - 0.015 15.0 0.3 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 EDN92389.1 - 4.3e-108 361.7 23.9 5e-108 361.5 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN92389.1 - 4.1e-36 124.4 31.3 1.3e-19 70.1 6.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EDN92389.1 - 0.013 13.6 3.5 1 7.3 0.8 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 EDN92389.1 - 0.57 8.3 17.3 0.006 14.8 1.5 2.9 2 1 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Peptidase_M20 PF01546.23 EDN92390.1 - 6.1e-10 38.9 0.1 8.6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN92390.1 - 6.3e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 EDN92392.1 - 0.002 16.8 1.6 0.002 16.8 1.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.23 EDN92394.1 - 1.9e-11 43.7 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EDN92394.1 - 0.034 13.7 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GST_N_2 PF13409.1 EDN92395.1 - 1.5e-21 76.1 0.0 2.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN92395.1 - 5.3e-09 35.8 0.0 1.7e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN92395.1 - 2.9e-06 27.4 0.1 0.00032 20.8 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN92395.1 - 9.3e-06 25.5 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN92395.1 - 8.9e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.16 EDN92396.1 - 1.7e-50 170.3 0.0 2.4e-30 105.1 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EDN92396.1 - 4e-42 143.3 0.3 1.4e-41 141.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EDN92396.1 - 7.7e-36 121.4 1.5 3.3e-25 87.4 0.3 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDN92396.1 - 1.5e-24 85.0 1.1 5.5e-21 73.6 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site FKBP_C PF00254.23 EDN92397.1 - 5.5e-29 100.0 0.0 7.6e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Siva PF05458.7 EDN92398.1 - 0.018 14.6 0.8 0.02 14.4 0.5 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Chitin_synth_1 PF01644.12 EDN92402.1 - 7.8e-83 276.1 0.1 1.1e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDN92402.1 - 4.9e-33 112.6 0.5 1.1e-32 111.5 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDN92402.1 - 1.8e-23 82.7 1.4 3.8e-21 75.0 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN92402.1 - 3.6e-08 33.3 7.2 1.5e-07 31.3 5.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN92402.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Senescence PF06911.7 EDN92403.1 - 1.8e-47 161.3 8.3 2.4e-47 160.9 5.7 1.2 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.13 EDN92406.1 - 5e-20 71.4 0.0 9.4e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mit_ribos_Mrp51 PF11709.3 EDN92408.1 - 9.2e-65 218.9 0.2 1e-64 218.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Asp PF00026.18 EDN92409.1 - 3.7e-08 32.9 1.2 5.6e-08 32.4 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SH3_2 PF07653.12 EDN92410.1 - 1.6e-10 40.2 0.0 3.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN92410.1 - 1.6e-09 36.9 0.1 1.6e-09 36.9 0.1 2.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EDN92410.1 - 2.3e-09 36.6 0.1 7.9e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EDN92411.1 - 5.6e-19 68.0 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EDN92412.1 - 5.4e-59 197.3 0.4 6.5e-59 197.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EDN92412.1 - 0.029 15.0 0.1 0.04 14.6 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Hist_deacetyl PF00850.14 EDN92413.1 - 1.5e-60 205.1 0.0 2.2e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TGT PF01702.13 EDN92414.1 - 3.6e-88 294.8 0.0 4.5e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF837 PF05769.6 EDN92416.1 - 0.0041 16.6 0.2 0.0043 16.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Prefoldin_2 PF01920.15 EDN92416.1 - 0.07 12.9 1.2 0.071 12.8 0.9 1.1 1 0 0 1 1 1 0 Prefoldin subunit WSC PF01822.14 EDN92417.1 - 1.7e-44 149.6 49.1 1.5e-17 63.3 6.6 4.3 4 0 0 4 4 4 3 WSC domain Glyoxal_oxid_N PF07250.6 EDN92417.1 - 1e-22 80.4 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 EDN92417.1 - 2.4 8.0 5.2 1.8 8.4 0.1 3.5 4 0 0 4 4 4 0 Kelch motif Glyco_hydro_16 PF00722.16 EDN92419.1 - 3.5e-18 65.5 0.8 1.1e-17 63.9 0.3 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EDN92420.1 - 7.2e-49 166.1 0.9 7.2e-49 166.1 0.7 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN92420.1 - 7.6e-08 32.4 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDN92420.1 - 0.013 15.2 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 SUV3_C PF12513.3 EDN92421.1 - 2.8e-16 58.6 0.1 7.4e-16 57.3 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EDN92421.1 - 1.4e-08 34.4 0.0 3.9e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.16 EDN92422.1 - 4e-31 106.4 0.1 6e-31 105.8 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EDN92422.1 - 6.9e-22 76.8 0.0 1.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain PolyA_pol PF01743.15 EDN92424.1 - 5.8e-26 91.1 0.2 1e-25 90.3 0.2 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EDN92424.1 - 3.6e-07 29.6 0.0 9.8e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A RE_NgoBV PF09564.5 EDN92424.1 - 0.077 12.2 0.4 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 NgoBV restriction endonuclease TRAPPC-Trs85 PF12739.2 EDN92426.1 - 7.9e-90 301.4 0.6 1e-89 301.0 0.4 1.0 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DnaJ PF00226.26 EDN92427.1 - 3.6e-15 55.4 0.1 5.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2454 PF10521.4 EDN92429.1 - 8.3e-71 238.2 6.8 1.2e-70 237.7 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 EDN92429.1 - 0.015 15.7 0.0 0.055 13.9 0.0 2.1 1 0 0 1 1 1 0 HEAT-like repeat UPF0146 PF03686.8 EDN92429.1 - 0.082 12.7 0.4 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MMS19_C PF12460.3 EDN92429.1 - 5.8 5.5 11.1 0.33 9.6 0.5 2.7 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF1237 PF06824.6 EDN92432.1 - 1.2e-184 613.8 0.0 1.4e-184 613.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 EDN92433.1 - 2.6e-77 260.8 43.7 6.7e-77 259.5 30.3 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4 PF00097.20 EDN92434.1 - 8.6e-08 31.7 15.4 8.6e-08 31.7 10.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN92434.1 - 3.2e-07 29.9 15.5 9.3e-07 28.4 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN92434.1 - 7.4e-07 29.0 15.1 7.4e-07 29.0 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN92434.1 - 1.7e-06 27.6 14.6 1.7e-06 27.6 10.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EDN92434.1 - 5.6e-06 26.0 4.8 5.6e-06 26.0 3.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EDN92434.1 - 7.3e-06 25.7 14.1 7.3e-06 25.7 9.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EDN92434.1 - 0.00013 21.6 10.1 0.00013 21.6 7.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDN92434.1 - 0.00015 21.5 13.8 0.00015 21.5 9.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EDN92434.1 - 0.0002 21.2 0.0 0.00075 19.4 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EDN92434.1 - 0.0014 18.7 6.2 0.0014 18.7 4.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger Mob_synth_C PF06463.8 EDN92434.1 - 0.0016 18.1 3.8 0.016 14.8 0.6 2.8 3 0 0 3 3 3 1 Molybdenum Cofactor Synthesis C Sgf11 PF08209.6 EDN92434.1 - 0.0069 15.6 0.6 0.0069 15.6 0.4 2.1 2 1 1 3 3 2 1 Sgf11 (transcriptional regulation protein) SAP PF02037.22 EDN92434.1 - 0.022 14.2 0.1 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 SAP domain zf-RING_4 PF14570.1 EDN92434.1 - 1 9.0 15.1 0.021 14.3 4.8 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Snf7 PF03357.16 EDN92435.1 - 8e-18 64.3 17.5 8e-18 64.3 12.1 1.9 1 1 0 1 1 1 1 Snf7 GAGA_bind PF06217.7 EDN92435.1 - 0.39 10.6 6.8 0.64 9.9 4.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Syja_N PF02383.13 EDN92436.1 - 2e-58 197.6 0.1 2.7e-35 121.6 0.0 2.4 2 0 0 2 2 2 2 SacI homology domain DUF1301 PF06979.7 EDN92436.1 - 0.027 14.6 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) HATPase_c PF02518.21 EDN92439.1 - 7.7e-24 83.5 0.0 1.4e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN92439.1 - 6e-19 68.1 0.6 2.9e-18 65.8 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EDN92439.1 - 2e-09 37.2 0.0 4.9e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EDN92439.1 - 0.024 14.2 0.4 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.5 EDN92439.1 - 0.073 13.1 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 PAS fold Phage_holin_4 PF05105.7 EDN92442.1 - 0.073 12.7 0.3 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Holin family DndB PF14072.1 EDN92444.1 - 0.077 12.1 0.0 0.083 12.0 0.0 1.0 1 0 0 1 1 1 0 DNA-sulfur modification-associated YodL PF14191.1 EDN92444.1 - 0.078 13.4 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 YodL-like DUF4470 PF14737.1 EDN92445.1 - 3.6e-09 36.2 0.0 6.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Imm31 PF15595.1 EDN92445.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 31 RAM PF15320.1 EDN92446.1 - 0.13 12.5 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein zf-C3HC4_3 PF13920.1 EDN92449.1 - 0.00078 19.0 3.0 0.0015 18.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 EDN92449.1 - 0.022 14.5 0.3 0.031 14.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-C3HC4_2 PF13923.1 EDN92449.1 - 0.036 14.0 4.1 0.036 14.0 2.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN92449.1 - 0.11 12.3 7.2 0.095 12.5 3.1 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EDN92449.1 - 0.5 10.0 5.5 1.2 8.8 3.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-H PF05837.7 EDN92450.1 - 0.001 19.2 1.5 0.0013 18.8 1.0 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Myb_DNA-bind_5 PF13873.1 EDN92450.1 - 0.0019 18.0 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain adh_short PF00106.20 EDN92451.1 - 1e-16 61.3 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN92451.1 - 1.8e-10 41.0 0.0 2.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN92451.1 - 1.5e-07 31.2 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDN92451.1 - 0.0053 16.5 0.5 0.0092 15.7 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EDN92451.1 - 0.034 14.2 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EDN92451.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RPA_C PF08784.6 EDN92452.1 - 5.1e-19 68.5 0.2 1.9e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EDN92452.1 - 1.9e-07 30.8 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Acetyltransf_7 PF13508.1 EDN92453.1 - 4e-09 36.4 1.2 4.8e-09 36.2 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN92453.1 - 6.3e-07 29.3 0.1 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDN92453.1 - 2.8e-05 23.9 0.2 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN92453.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EDN92453.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN92453.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DEAD PF00270.24 EDN92459.1 - 3.4e-44 150.3 0.0 7.6e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EDN92459.1 - 9.2e-23 79.8 4.3 9.2e-23 79.8 3.0 2.1 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EDN92459.1 - 1.9e-21 75.6 0.1 8.4e-21 73.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN92459.1 - 0.0038 16.0 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDN92459.1 - 0.014 15.2 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 EDN92460.1 - 2.9e-45 153.7 0.1 6.4e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDN92460.1 - 4.6e-25 86.9 0.0 1.1e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDN92460.1 - 1.2e-21 76.3 0.0 2.6e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAPS_reduct PF01507.14 EDN92461.1 - 4.3e-30 104.7 0.0 9.3e-21 74.4 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Sad1_UNC PF07738.8 EDN92462.1 - 3e-07 30.3 0.0 1.7e-05 24.6 0.0 2.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4327 PF14217.1 EDN92462.1 - 0.017 14.9 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Dppa2_A PF14049.1 EDN92462.1 - 0.085 12.7 0.5 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Spore_II_R PF09551.5 EDN92462.1 - 0.34 10.9 2.6 0.98 9.4 1.8 1.7 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Epimerase PF01370.16 EDN92463.1 - 5.1e-46 157.0 0.0 6.6e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EDN92463.1 - 1.2e-25 89.2 0.1 2.2e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EDN92463.1 - 2.8e-17 62.3 0.0 8.9e-17 60.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN92463.1 - 2.2e-13 49.7 0.0 5.2e-12 45.2 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDN92463.1 - 3.8e-13 49.7 0.0 6.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EDN92463.1 - 1.5e-11 43.7 0.0 4.2e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EDN92463.1 - 7.4e-10 38.1 0.0 2.6e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EDN92463.1 - 8.3e-10 38.6 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN92463.1 - 1.9e-08 34.5 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN92463.1 - 0.0039 16.4 0.0 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EDN92463.1 - 0.0085 15.4 0.2 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EDN92463.1 - 0.019 13.9 0.3 0.04 12.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Methyltransf_18 PF12847.2 EDN92463.1 - 0.053 14.0 0.0 13 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 EDN92463.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EDN92464.1 - 1.4e-34 118.4 0.2 5.4e-34 116.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN92464.1 - 2.4e-15 57.5 0.0 5e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN92464.1 - 2.2e-08 33.7 0.0 2.3e-07 30.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EDN92465.1 - 4.1e-11 42.1 45.0 6.7e-11 41.5 24.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EDN92467.1 - 8.5e-16 57.8 0.0 1.7e-13 50.3 0.0 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92467.1 - 0.0028 16.7 0.0 0.75 8.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Methyltransf_2 PF00891.13 EDN92468.1 - 0.00069 18.8 0.0 0.00076 18.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Nipped-B_C PF12830.2 EDN92471.1 - 2.6e-49 167.4 2.8 6.1e-49 166.2 0.4 2.8 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EDN92471.1 - 6e-12 45.2 0.5 1.4e-10 40.8 0.1 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EDN92471.1 - 0.0013 18.6 0.1 2.7 8.3 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EDN92472.1 - 1.8e-32 111.4 2.5 2.2e-14 53.4 0.0 3.4 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EDN92472.1 - 1.1e-19 68.8 1.3 8.9e-05 22.6 0.1 6.4 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.17 EDN92472.1 - 3.9e-07 29.6 2.9 4 7.7 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EDN92472.1 - 1.8e-06 28.2 6.0 0.17 12.4 0.1 4.6 2 2 2 4 4 4 3 HEAT-like repeat DHQ_synthase PF01761.15 EDN92473.1 - 2e-53 181.0 0.0 2.7e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EDN92473.1 - 9.2e-12 44.7 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase VIT_2 PF13757.1 EDN92473.1 - 0.078 12.4 0.1 0.69 9.4 0.0 2.6 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain DUF1730 PF08331.5 EDN92473.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Methyltransf_24 PF13578.1 EDN92474.1 - 1.1e-12 48.7 0.0 1.5e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EDN92474.1 - 2.4e-12 46.3 0.0 3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EDN92474.1 - 0.012 16.1 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EDN92474.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase PCMT PF01135.14 EDN92474.1 - 0.055 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EDN92474.1 - 0.068 12.7 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DDE_1 PF03184.14 EDN92476.1 - 2.7e-21 75.7 0.1 4.2e-21 75.0 0.0 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3404 PF11884.3 EDN92476.1 - 0.00049 19.0 0.1 0.57 9.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3404) PH_8 PF15409.1 EDN92476.1 - 0.077 13.0 0.2 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CytochromB561_N PF09786.4 EDN92479.1 - 0.068 11.6 0.1 0.082 11.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal KRTAP PF11759.3 EDN92479.1 - 0.092 13.0 11.9 0.11 12.7 4.7 2.5 2 0 0 2 2 2 0 Keratin-associated matrix DUF1681 PF07933.9 EDN92480.1 - 1.7e-60 203.2 0.0 2.2e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DHHA1 PF02272.14 EDN92480.1 - 0.018 14.7 0.3 0.039 13.6 0.2 1.6 1 0 0 1 1 1 0 DHHA1 domain IF-2B PF01008.12 EDN92481.1 - 4.6e-51 173.4 0.0 5.3e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1942 PF09167.6 EDN92481.1 - 0.011 15.5 0.9 0.098 12.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) UPF0086 PF01868.11 EDN92483.1 - 2.5e-23 81.5 0.1 3.9e-23 80.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 HPS3_Mid PF14762.1 EDN92483.1 - 0.096 11.2 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Acyltransferase PF01553.16 EDN92484.1 - 6.3e-06 25.6 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.1 EDN92484.1 - 0.025 14.3 0.2 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain ADH_zinc_N PF00107.21 EDN92485.1 - 6e-26 90.5 0.3 8.8e-26 89.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN92485.1 - 2.2e-15 57.6 0.0 5e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN92485.1 - 1.2e-09 37.8 0.0 3.5e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EDN92485.1 - 0.00026 20.9 0.0 0.00052 19.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EDN92485.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.13 EDN92488.1 - 4.5e-09 36.0 7.6 7.3e-09 35.4 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN92488.1 - 4.4e-05 22.4 0.0 0.29 9.9 0.0 2.9 2 1 1 3 3 3 2 Fungal specific transcription factor domain Sulfate_transp PF00916.15 EDN92490.1 - 3.1e-54 183.8 4.3 3.1e-54 183.8 3.0 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDN92490.1 - 2.7e-30 103.8 2.8 9.8e-30 102.0 2.0 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDN92490.1 - 3.8e-15 55.3 0.0 7.8e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EDN92490.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.7 1 0 0 1 1 1 1 STAS domain ECH PF00378.15 EDN92491.1 - 8.1e-31 107.0 0.0 1.3e-29 103.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peripla_BP_2 PF01497.13 EDN92491.1 - 0.034 13.2 0.0 0.069 12.2 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein OPT PF03169.10 EDN92492.1 - 2.8e-180 600.8 54.3 3.2e-180 600.6 37.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EDN92492.1 - 0.67 9.0 3.2 1.7 7.7 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FNIP_N PF14636.1 EDN92496.1 - 4e-31 108.2 0.3 4e-31 108.2 0.2 4.4 4 1 0 5 5 5 1 Folliculin-interacting protein N-terminus MBD_C PF14048.1 EDN92496.1 - 0.0068 16.9 0.0 0.055 14.0 0.0 2.6 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 C9orf72-like PF15019.1 EDN92496.1 - 0.14 11.4 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 C9orf72-like protein family Tannase PF07519.6 EDN92498.1 - 9.2e-122 407.1 3.7 1.2e-121 406.7 2.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2953 PF11167.3 EDN92499.1 - 0.058 13.3 0.2 0.072 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Fungal_trans_2 PF11951.3 EDN92501.1 - 4.8e-11 41.8 1.4 2.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain WD40 PF00400.27 EDN92502.1 - 2.4e-10 39.8 1.8 0.37 10.7 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 EDN92503.1 - 0.0012 18.8 0.3 0.0058 16.6 0.2 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Pho86 PF11124.3 EDN92503.1 - 0.009 15.0 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_7 PF13508.1 EDN92503.1 - 0.044 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN92503.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN92503.1 - 0.12 12.2 0.2 1.3 8.9 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_2 PF03446.10 EDN92504.1 - 9.2e-33 113.3 0.1 1.5e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EDN92504.1 - 3.7e-30 104.4 0.0 6.6e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EDN92504.1 - 3.5e-05 22.7 0.1 5.4e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family MMS1_N PF10433.4 EDN92505.1 - 3.2e-67 226.8 0.0 5.2e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EDN92505.1 - 8.2e-61 205.8 0.0 2.1e-60 204.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region BBS2_Mid PF14783.1 EDN92505.1 - 0.13 11.9 0.0 3.6 7.4 0.0 3.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Sin_N PF04801.8 EDN92506.1 - 1.9e-23 83.0 3.5 5.3e-23 81.5 2.4 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region Pmp3 PF01679.12 EDN92507.1 - 6e-21 73.8 4.8 7.7e-21 73.5 3.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator IPK PF03770.11 EDN92508.1 - 1.2e-51 175.2 0.0 1.9e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 EDN92508.1 - 1.3e-25 90.3 0.0 2.2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Dynamin_N PF00350.18 EDN92508.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Arb1 PF09692.5 EDN92510.1 - 1.4e-148 494.9 0.1 2.2e-148 494.3 0.1 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DDE_1 PF03184.14 EDN92511.1 - 3.5e-16 59.0 0.0 9e-16 57.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN92511.1 - 4.2e-07 29.6 0.3 1.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain MFS_1 PF07690.11 EDN92512.1 - 2.3e-36 125.2 74.1 3.7e-30 104.8 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN92512.1 - 2.4e-09 36.2 15.9 2.4e-09 36.2 11.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EDN92512.1 - 4.3e-08 31.9 16.9 4.3e-08 31.9 11.7 2.5 1 1 2 3 3 3 2 MFS/sugar transport protein Aldo_ket_red PF00248.16 EDN92513.1 - 3.3e-64 216.4 0.0 3.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1978 PF09321.5 EDN92515.1 - 0.022 14.1 0.8 0.29 10.5 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) UPRTase PF14681.1 EDN92517.1 - 4.3e-43 146.9 0.0 7.3e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EDN92517.1 - 7.1e-16 58.3 0.0 1.9e-10 40.5 0.0 2.3 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family Pribosyltran PF00156.22 EDN92517.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CLTH PF10607.4 EDN92518.1 - 1.5e-14 53.8 0.2 1.1e-11 44.6 0.1 2.2 1 1 1 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EDN92518.1 - 3.7e-09 36.0 0.0 6.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 LisH Pyr_redox_2 PF07992.9 EDN92519.1 - 8.3e-21 74.7 0.0 1.2e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN92519.1 - 5e-13 49.2 0.0 1.1e-10 41.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EDN92519.1 - 5.1e-07 28.5 0.4 1.2e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN92519.1 - 8.9e-06 25.7 0.2 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EDN92519.1 - 9.5e-06 24.7 1.1 2.4e-05 23.4 0.7 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EDN92519.1 - 4.4e-05 23.0 0.4 0.00014 21.4 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain Pyr_redox_3 PF13738.1 EDN92519.1 - 0.015 15.3 0.0 7.4 6.5 0.0 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Myc_N PF01056.13 EDN92519.1 - 0.2 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Lactonase PF10282.4 EDN92520.1 - 5.2e-75 252.6 0.0 7.4e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Epimerase PF01370.16 EDN92523.1 - 4.8e-08 32.7 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EDN92523.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TPR_17 PF13431.1 EDN92523.1 - 0.094 12.9 0.1 0.29 11.4 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Aa_trans PF01490.13 EDN92524.1 - 3e-29 101.7 31.2 1.1e-28 99.8 21.6 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein NIR_SIR PF01077.17 EDN92525.1 - 9.5e-51 171.2 0.0 7.1e-45 152.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EDN92525.1 - 2.9e-31 106.9 0.0 6.7e-16 57.6 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EDN92525.1 - 1.8e-29 102.5 0.0 6.1e-29 100.8 0.0 2.0 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EDN92525.1 - 0.025 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EDN92526.1 - 1.9e-61 207.0 5.5 2.6e-61 206.5 3.8 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.17 EDN92527.1 - 3e-56 189.2 0.1 3.7e-56 188.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN92527.1 - 7.6e-19 68.3 0.1 1.6e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN92527.1 - 5.6e-15 55.0 0.4 6.4e-15 54.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN92527.1 - 3.4e-07 29.9 0.0 6.3e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN92527.1 - 0.0023 17.1 0.2 0.0027 16.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDN92527.1 - 0.0044 16.2 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Nop53 PF07767.6 EDN92528.1 - 4.5e-113 378.1 29.9 5.5e-113 377.8 20.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FAM219A PF15260.1 EDN92528.1 - 0.63 10.3 4.9 1.7 8.9 1.7 2.7 2 0 0 2 2 2 0 Protein family FAM219A LCD1 PF09798.4 EDN92528.1 - 1.4 6.8 6.6 2.2 6.2 4.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Voltage_CLC PF00654.15 EDN92530.1 - 1.5e-88 297.1 27.8 1.5e-88 297.1 19.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EDN92530.1 - 3.5e-13 49.1 1.2 9.9e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 CBS domain Nuc_deoxyrib_tr PF05014.10 EDN92531.1 - 0.042 13.7 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Myb_DNA-bind_5 PF13873.1 EDN92532.1 - 0.0029 17.4 0.7 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Sugar_tr PF00083.19 EDN92535.1 - 3.9e-79 266.3 24.8 5e-79 265.9 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN92535.1 - 2.8e-19 69.0 34.7 2.8e-19 69.0 24.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN92535.1 - 2e-12 46.2 18.4 1.3e-07 30.4 1.7 2.7 2 2 1 3 3 3 2 MFS/sugar transport protein HlyIII PF03006.15 EDN92535.1 - 1.6 8.1 11.3 0.2 11.0 4.6 1.9 2 1 0 2 2 2 0 Haemolysin-III related Acetyltransf_3 PF13302.1 EDN92537.1 - 2.7e-10 40.5 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN92537.1 - 7.3e-08 32.3 0.1 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDN92537.1 - 1.2e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDN92537.1 - 0.00033 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN92537.1 - 0.02 15.0 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN92537.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.26 EDN92540.1 - 5.6e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.13 EDN92543.1 - 2.8e-12 46.0 0.0 4.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiF PF00899.16 EDN92544.1 - 1.2e-09 38.1 0.0 3.5e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.9 EDN92545.1 - 1.5e-39 135.0 0.0 1e-32 112.8 0.0 3.1 2 1 1 3 3 3 3 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) GMC_oxred_C PF05199.8 EDN92546.1 - 3.3e-09 37.1 0.2 4e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase TelA PF05816.6 EDN92548.1 - 0.0072 15.0 5.6 0.01 14.5 3.9 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Tropomyosin_1 PF12718.2 EDN92548.1 - 0.0097 15.7 4.3 0.015 15.1 3.0 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF972 PF06156.8 EDN92548.1 - 0.012 15.8 3.6 0.022 15.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CD99L2 PF12301.3 EDN92548.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Cluap1 PF10234.4 EDN92548.1 - 0.042 13.0 2.8 0.063 12.4 2.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Atg14 PF10186.4 EDN92548.1 - 0.077 11.9 4.6 0.11 11.3 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EDN92548.1 - 0.09 12.7 1.7 0.13 12.1 1.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.8 EDN92548.1 - 0.31 10.4 3.3 0.47 9.8 2.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Tropomyosin_1 PF12718.2 EDN92549.1 - 0.0042 16.9 14.4 0.0088 15.8 10.0 1.6 1 0 0 1 1 1 1 Tropomyosin like IncA PF04156.9 EDN92549.1 - 0.037 13.6 6.2 0.056 13.0 4.3 1.2 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EDN92549.1 - 0.3 10.8 12.3 0.66 9.7 8.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EDN92549.1 - 0.88 9.4 11.9 0.21 11.4 1.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SPX PF03105.14 EDN92549.1 - 7.9 6.1 13.5 21 4.7 9.4 1.6 1 1 0 1 1 1 0 SPX domain FCH PF00611.18 EDN92553.1 - 0.059 13.5 1.0 0.33 11.1 0.3 2.4 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF221 PF02714.10 EDN92555.1 - 2.1e-112 375.1 28.0 1.7e-111 372.2 17.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN92555.1 - 2.6e-47 160.2 0.6 1e-46 158.3 0.4 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDN92555.1 - 3e-31 107.1 0.1 1.5e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN92555.1 - 4.2e-19 68.8 0.1 7.1e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DnaJ PF00226.26 EDN92556.1 - 1.8e-13 50.0 0.2 6.3e-13 48.2 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EDN92557.1 - 7.7e-35 120.1 0.3 5.5e-29 100.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3357 PF11837.3 EDN92558.1 - 0.026 14.3 0.1 0.063 13.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) bZIP_1 PF00170.16 EDN92560.1 - 0.57 10.1 9.3 1.4 8.9 6.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor DUF605 PF04652.11 EDN92560.1 - 3 7.1 14.5 3.5 6.9 10.1 1.1 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 EDN92562.1 - 3.4e-120 401.6 29.9 3.8e-120 401.5 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN92562.1 - 2.2e-20 72.6 45.4 1.7e-15 56.6 11.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN92562.1 - 7.5e-07 27.8 25.8 0.0015 16.9 7.0 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 EDN92562.1 - 0.002 16.4 1.7 0.002 16.4 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ald_Xan_dh_C2 PF02738.13 EDN92565.1 - 6.6e-178 592.4 0.0 8.5e-178 592.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EDN92565.1 - 1.1e-38 132.3 0.0 2.3e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EDN92565.1 - 5.3e-33 113.0 0.1 3.7e-32 110.3 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EDN92565.1 - 1.5e-25 88.8 0.0 3.7e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EDN92565.1 - 6.9e-25 87.2 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_3 PF01494.14 EDN92566.1 - 1.3e-82 277.6 0.0 1.8e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDN92566.1 - 7.4e-12 45.2 0.0 2.9e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EDN92566.1 - 1.4e-06 28.3 0.0 6.6e-05 22.8 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN92566.1 - 2.7e-06 26.5 0.1 1.6e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN92566.1 - 8.3e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN92566.1 - 1.2e-05 25.6 0.0 0.0005 20.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN92566.1 - 2.3e-05 23.0 0.0 7.1e-05 21.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EDN92566.1 - 0.00069 18.7 0.0 0.0033 16.5 0.0 2.0 1 1 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EDN92566.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EDN92566.1 - 0.0031 16.3 0.0 0.0067 15.2 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EDN92566.1 - 0.0042 16.0 0.1 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EDN92566.1 - 0.0073 15.2 0.0 0.02 13.7 0.0 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDN92566.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EDN92566.1 - 0.011 14.6 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EDN92566.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EDN92566.1 - 0.013 15.4 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EDN92566.1 - 0.016 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EDN92566.1 - 0.049 12.2 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EDN92566.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EDN92566.1 - 0.064 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding F420_oxidored PF03807.12 EDN92566.1 - 0.074 13.4 0.0 9.2 6.7 0.0 3.3 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 EDN92566.1 - 0.09 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain FAD_binding_3 PF01494.14 EDN92567.1 - 4.5e-15 55.5 0.0 5.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN92567.1 - 2.9e-10 39.6 0.7 0.00042 19.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN92567.1 - 4e-06 26.7 1.2 1.2e-05 25.2 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN92567.1 - 0.00029 19.8 6.3 0.015 14.1 4.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDN92567.1 - 0.0017 18.4 0.4 0.013 15.5 0.3 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EDN92567.1 - 0.0038 16.1 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.9 EDN92567.1 - 0.04 13.7 3.2 0.24 11.2 2.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN92567.1 - 0.042 12.9 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN92567.1 - 0.071 11.5 3.2 0.045 12.2 1.0 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EDN92567.1 - 0.3 9.8 5.1 0.46 9.2 3.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDN92567.1 - 0.34 10.5 2.7 0.72 9.4 1.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EDN92567.1 - 1.9 8.9 5.8 0.71 10.3 1.8 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CTP_transf_1 PF01148.15 EDN92568.1 - 9.3e-74 248.3 26.2 1.1e-73 248.1 18.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EDN92569.1 - 1.1e-52 177.5 0.0 2.4e-52 176.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Tropomyosin_1 PF12718.2 EDN92569.1 - 0.025 14.4 17.6 0.05 13.4 12.2 1.4 1 0 0 1 1 1 0 Tropomyosin like Uso1_p115_C PF04871.8 EDN92569.1 - 0.051 13.5 11.3 0.1 12.4 7.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ax_dynein_light PF10211.4 EDN92569.1 - 0.4 10.4 13.4 0.28 10.9 7.7 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain GMC_oxred_N PF00732.14 EDN92572.1 - 7.3e-64 215.7 0.0 1.1e-63 215.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN92572.1 - 1.7e-38 132.1 0.1 3e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Asp PF00026.18 EDN92572.1 - 2.4e-06 27.0 0.0 0.11 11.7 0.0 3.2 4 0 0 4 4 4 2 Eukaryotic aspartyl protease NAD_binding_8 PF13450.1 EDN92572.1 - 0.0002 21.3 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN92572.1 - 0.00053 18.9 0.0 0.03 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EDN92572.1 - 0.0016 17.4 0.2 0.0041 16.0 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EDN92572.1 - 0.046 13.7 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EDN92572.1 - 0.047 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EDN92572.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Amidoligase_2 PF12224.3 EDN92573.1 - 2.3e-33 115.8 0.3 2.3e-32 112.6 0.2 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme Aminotran_3 PF00202.16 EDN92576.1 - 1.1e-35 123.1 0.0 5.1e-21 74.8 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EDN92576.1 - 2.3e-28 99.1 0.0 4.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 EDN92577.1 - 6.7e-27 94.3 0.0 9.6e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II BATS PF06968.8 EDN92578.1 - 1.2e-23 82.7 0.0 3e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EDN92578.1 - 8.6e-20 71.5 0.2 3e-19 69.7 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily HrpB7 PF09486.5 EDN92584.1 - 0.0012 18.7 1.0 0.0018 18.2 0.7 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 EDN92584.1 - 0.022 14.3 0.5 0.031 13.8 0.4 1.1 1 0 0 1 1 1 0 IncA protein OmpH PF03938.9 EDN92584.1 - 0.078 12.9 0.3 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MSSP PF03940.8 EDN92585.1 - 3.1 7.2 12.6 22 4.5 8.8 2.2 1 1 0 1 1 1 0 Male specific sperm protein EAP30 PF04157.11 EDN92586.1 - 1.2e-54 184.8 0.0 1.4e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EDN92586.1 - 2.3e-06 27.3 0.0 0.037 13.8 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.2 EDN92586.1 - 0.003 17.3 6.5 0.33 10.8 0.4 2.3 2 0 0 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.13 EDN92586.1 - 0.024 13.7 12.1 0.069 12.2 0.7 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Mu-like_Com PF10122.4 EDN92586.1 - 0.075 12.0 0.9 0.81 8.7 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.1 EDN92586.1 - 0.39 9.9 6.9 2.1 7.6 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EDN92586.1 - 0.97 9.0 6.1 0.67 9.5 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain SAC3_GANP PF03399.11 EDN92587.1 - 8.1e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SH3_1 PF00018.23 EDN92591.1 - 4.8e-26 89.8 0.1 4.4e-12 45.1 0.0 3.0 4 0 0 4 4 4 2 SH3 domain SH3_9 PF14604.1 EDN92591.1 - 3.7e-14 52.0 0.2 1.2e-05 24.7 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EDN92591.1 - 3.9e-14 52.4 0.0 8.1e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EDN92591.1 - 8.3e-12 44.4 0.0 4.2e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EDN92591.1 - 2.9e-08 33.2 0.1 5e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain DBD_Tnp_Mut PF03108.10 EDN92592.1 - 1.1e-12 47.3 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 MuDR family transposase DUF605 PF04652.11 EDN92592.1 - 4.2 6.6 7.1 5.8 6.2 4.9 1.1 1 0 0 1 1 1 0 Vta1 like Thymidylat_synt PF00303.14 EDN92593.1 - 2.8e-110 367.5 0.0 3.4e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase adh_short PF00106.20 EDN92594.1 - 6e-25 88.0 0.2 1e-24 87.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN92594.1 - 2.3e-17 63.5 0.0 3.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDN92594.1 - 5.3e-06 26.5 0.1 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EDN92594.1 - 6.2e-05 22.5 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EDN92594.1 - 0.0001 21.6 0.1 0.00024 20.4 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.5 EDN92594.1 - 0.018 14.1 0.0 3.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EDN92594.1 - 0.054 12.3 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 EDN92594.1 - 0.058 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EDN92594.1 - 0.092 12.3 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hexapep PF00132.19 EDN92595.1 - 1.7e-14 52.5 22.0 1.1e-08 34.1 6.2 4.0 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN92595.1 - 1.5e-12 46.8 20.4 3.4e-08 32.9 5.1 4.4 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EDN92595.1 - 0.076 13.0 0.5 0.42 10.6 0.3 2.0 1 1 0 1 1 1 0 Maltose acetyltransferase MTP18 PF10558.4 EDN92596.1 - 3e-53 179.7 0.0 4.9e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EDN92597.1 - 1.1e-30 105.4 0.6 1.3e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) gp12-short_mid PF09089.5 EDN92597.1 - 0.078 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain DUF2681 PF10883.3 EDN92598.1 - 0.012 15.8 0.2 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Vfa1 PF08432.5 EDN92598.1 - 0.069 13.1 2.0 0.077 13.0 1.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.7 EDN92598.1 - 0.075 12.2 3.0 0.077 12.1 2.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF755 PF05501.6 EDN92598.1 - 0.31 11.0 7.2 0.39 10.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3246 PF11596.3 EDN92598.1 - 0.59 9.3 8.8 0.71 9.1 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MFMR PF07777.6 EDN92598.1 - 1.9 8.3 7.0 2.2 8.1 4.8 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR Sec16_C PF12931.2 EDN92599.1 - 0.074 12.7 0.1 0.074 12.7 0.1 1.0 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DUF1077 PF06417.7 EDN92600.1 - 2.5e-53 178.7 0.9 3e-53 178.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EDN92601.1 - 9.7e-131 436.6 7.1 1.2e-130 436.3 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDN92601.1 - 3.9e-17 62.6 1.6 1.4e-16 60.8 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDN92601.1 - 1.3e-15 57.4 3.4 1.2e-09 38.3 0.1 4.4 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EDN92601.1 - 2.3e-09 36.5 2.7 0.01 15.8 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EDN92601.1 - 8.9e-05 22.8 4.1 1.2 9.7 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EDN92601.1 - 0.00072 18.9 1.6 0.88 8.8 0.1 3.4 3 0 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.4 EDN92601.1 - 0.0019 17.9 0.0 0.66 9.7 0.0 3.9 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EDN92601.1 - 0.01 15.6 1.0 3.7 7.4 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ifi-6-16 PF06140.8 EDN92602.1 - 0.0087 15.8 5.0 0.016 14.9 3.4 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family Inhibitor_I53 PF11714.3 EDN92602.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Thrombin inhibitor Madanin TMEM154 PF15102.1 EDN92602.1 - 0.087 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 EDN92602.1 - 0.16 12.4 1.5 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NfeD PF01957.13 EDN92602.1 - 0.41 10.7 4.7 0.83 9.7 3.2 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF2207 PF09972.4 EDN92602.1 - 0.41 9.1 3.3 0.61 8.5 2.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Cofilin_ADF PF00241.15 EDN92603.1 - 3.2e-09 36.7 0.0 3.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sugar_tr PF00083.19 EDN92604.1 - 1.1e-36 126.4 24.4 1.5e-35 122.6 16.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN92604.1 - 4e-32 111.2 26.2 4.9e-25 87.9 5.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EDN92604.1 - 0.033 12.6 17.0 0.073 11.5 3.3 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like GDA1_CD39 PF01150.12 EDN92606.1 - 3.9e-109 365.0 0.0 5.2e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNase_PH PF01138.16 EDN92608.1 - 8e-27 94.1 0.0 2.8e-26 92.4 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 PAXNEB PF05625.6 EDN92611.1 - 7.3e-115 383.6 0.0 8.1e-115 383.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 EDN92612.1 - 6e-37 126.9 0.1 6.9e-37 126.7 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EDN92613.1 - 2.7e-08 33.5 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 EDN92614.1 - 4.9e-61 205.7 0.0 5.6e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA_int_endo PF01974.12 EDN92616.1 - 3.6e-15 55.5 0.0 6.5e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Anp1 PF03452.9 EDN92617.1 - 4.9e-121 403.0 0.0 7.8e-121 402.3 0.0 1.3 1 0 0 1 1 1 1 Anp1 DUF1768 PF08719.6 EDN92617.1 - 0.53 10.0 6.1 1.5 8.5 4.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) Sec7 PF01369.15 EDN92618.1 - 1.7e-62 210.4 0.0 3e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EDN92618.1 - 9.4e-20 70.7 0.2 1.9e-12 46.9 0.1 3.4 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1495 PF07381.6 EDN92619.1 - 0.039 13.6 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) Abhydrolase_4 PF08386.5 EDN92622.1 - 1.1e-17 63.7 0.0 2.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EDN92622.1 - 1e-10 41.5 0.0 3.5e-08 33.2 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN92622.1 - 0.00024 21.0 0.0 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN92622.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DHC_N1 PF08385.7 EDN92623.1 - 7.2e-190 632.2 4.0 7.2e-190 632.2 2.8 4.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EDN92623.1 - 2.6e-132 441.1 9.6 2.6e-132 441.1 6.7 4.8 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EDN92623.1 - 3.2e-104 349.4 0.1 1.3e-103 347.3 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EDN92623.1 - 3.6e-78 262.2 0.0 9.5e-78 260.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EDN92623.1 - 6e-43 146.3 0.1 1.9e-42 144.7 0.1 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EDN92623.1 - 1.4e-41 142.2 0.8 2e-40 138.4 0.1 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EDN92623.1 - 6e-41 140.3 6.8 6e-41 140.3 4.7 2.1 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EDN92623.1 - 2.5e-31 108.2 0.6 1.1e-10 41.3 0.0 7.1 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EDN92623.1 - 2.6e-21 75.9 0.0 1.5e-19 70.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EDN92623.1 - 1.7e-15 57.3 0.0 0.011 15.9 0.0 6.2 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 EDN92623.1 - 3.2e-14 53.2 0.0 0.00078 19.6 0.0 5.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDN92623.1 - 5.8e-11 42.4 0.0 0.12 12.2 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EDN92623.1 - 3.6e-09 37.4 2.6 0.046 14.5 0.0 6.7 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.1 EDN92623.1 - 3.6e-08 33.7 3.8 0.035 14.3 0.0 6.1 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 EDN92623.1 - 3.7e-07 29.3 0.0 0.053 12.4 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 EDN92623.1 - 9.1e-06 24.9 0.8 0.49 9.5 0.0 4.3 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EDN92623.1 - 1e-05 25.1 0.1 0.88 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain ABC_tran PF00005.22 EDN92623.1 - 1.2e-05 25.6 0.2 1.9 8.7 0.0 5.3 4 0 0 4 4 4 1 ABC transporter AAA_16 PF13191.1 EDN92623.1 - 1.4e-05 25.1 18.6 0.15 12.0 0.1 8.6 8 2 1 9 9 7 2 AAA ATPase domain AAA_29 PF13555.1 EDN92623.1 - 3.2e-05 23.3 0.0 2 8.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDN92623.1 - 0.0001 21.8 0.0 2.1 7.7 0.0 4.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family Vps23_core PF09454.5 EDN92623.1 - 0.0015 18.1 2.0 0.1 12.1 0.3 2.9 2 0 0 2 2 2 1 Vps23 core domain RNA_helicase PF00910.17 EDN92623.1 - 0.0058 16.7 0.1 19 5.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase DUF258 PF03193.11 EDN92623.1 - 0.012 14.8 0.1 18 4.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN92623.1 - 0.018 14.4 4.9 9.1 5.6 0.1 4.6 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 EDN92623.1 - 0.023 14.3 0.3 7.4 6.2 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EDN92623.1 - 0.032 13.6 4.0 0.56 9.5 0.0 4.4 6 0 0 6 6 6 0 AAA domain ERM PF00769.14 EDN92623.1 - 1.2 8.6 22.9 2.3 7.6 1.3 3.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MAS20 PF02064.10 EDN92624.1 - 1e-21 77.0 0.1 1.1e-20 73.7 0.1 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.7 EDN92624.1 - 0.00018 20.9 0.2 0.00027 20.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) DUF1079 PF06435.6 EDN92624.1 - 0.015 15.2 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) TIP120 PF08623.5 EDN92624.1 - 0.017 14.7 0.8 0.025 14.1 0.5 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DcuA_DcuB PF03605.9 EDN92624.1 - 0.19 10.5 0.4 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter ABA_WDS PF02496.11 EDN92624.1 - 0.29 11.3 5.9 0.45 10.7 1.5 2.5 2 1 1 3 3 3 0 ABA/WDS induced protein Vps51 PF08700.6 EDN92625.1 - 1.2e-15 57.0 2.8 1.2e-15 57.0 1.9 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EDN92625.1 - 0.0005 19.9 1.9 0.0068 16.2 0.1 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_B PF00052.13 EDN92625.1 - 0.2 11.2 2.7 0.1 12.1 0.1 1.8 2 0 0 2 2 2 0 Laminin B (Domain IV) Fib_alpha PF08702.5 EDN92625.1 - 0.53 10.3 8.1 0.071 13.2 0.9 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EDN92625.1 - 2.9 6.7 8.4 0.57 9.0 1.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Metallophos PF00149.23 EDN92626.1 - 4.4e-30 104.5 0.1 6.1e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAR1 PF03101.10 EDN92627.1 - 0.00039 20.8 0.1 0.00086 19.7 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Med9 PF07544.8 EDN92627.1 - 0.016 14.8 1.9 0.043 13.5 1.3 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Apolipoprotein PF01442.13 EDN92627.1 - 0.031 13.7 1.3 0.054 13.0 0.9 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Radical_SAM PF04055.16 EDN92628.1 - 5.8e-25 88.3 0.1 1.3e-24 87.2 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EDN92628.1 - 7e-24 83.7 0.0 1.9e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EDN92628.1 - 9e-11 41.9 0.2 5.6e-08 32.9 0.0 2.7 3 0 0 3 3 3 2 Flavodoxin Cpn10 PF00166.16 EDN92629.1 - 5.3e-27 93.5 0.0 5.9e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_61 PF03443.9 EDN92630.1 - 1.1e-47 162.7 0.0 1.5e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_1 PF00187.14 EDN92630.1 - 0.00083 19.2 26.5 0.00083 19.2 18.4 2.4 3 0 0 3 3 3 1 Chitin recognition protein Pkinase PF00069.20 EDN92631.1 - 1e-59 201.8 0.0 1.6e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92631.1 - 1.9e-21 76.3 0.0 4.3e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDN92631.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EDN92632.1 - 6.8e-27 92.7 0.1 2e-26 91.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDN92632.1 - 1.1e-21 76.7 0.5 2.5e-21 75.6 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EDN92633.1 - 1.4e-120 402.2 0.6 1.4e-118 395.5 0.4 2.0 1 1 0 1 1 1 1 Svf1-like Histone PF00125.19 EDN92634.1 - 2.5e-10 40.3 0.2 3.3e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDN92634.1 - 9.5e-06 25.4 0.2 1.3e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EDN92634.1 - 0.00022 21.2 0.2 0.00034 20.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EDN92634.1 - 0.0006 19.9 0.3 0.001 19.2 0.2 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S Pmp3 PF01679.12 EDN92635.1 - 4e-08 32.8 2.1 5.1e-08 32.5 1.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SNF2_N PF00176.18 EDN92636.1 - 1.2e-69 234.4 0.1 1.6e-69 234.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDN92636.1 - 8e-15 54.6 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EDN92636.1 - 3.2e-11 42.9 0.0 7.4e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EDN92636.1 - 2.9e-10 39.8 7.4 6.6e-10 38.6 5.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN92636.1 - 3e-08 33.5 8.2 3e-08 33.5 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN92636.1 - 8.3e-07 28.5 8.7 9.8e-07 28.3 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN92636.1 - 5e-06 26.0 8.5 5e-06 26.0 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN92636.1 - 6.2e-06 25.8 6.3 1.5e-05 24.6 4.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDN92636.1 - 1.4e-05 25.0 6.7 4.5e-05 23.4 4.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger DEAD PF00270.24 EDN92636.1 - 0.00031 20.2 0.0 0.00074 19.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 EDN92636.1 - 0.00052 19.8 6.7 0.0011 18.8 4.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDN92636.1 - 0.00075 19.1 5.1 0.0023 17.5 3.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EDN92636.1 - 0.0011 18.4 6.8 0.003 17.0 4.5 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit ResIII PF04851.10 EDN92636.1 - 0.0056 16.5 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-Apc11 PF12861.2 EDN92636.1 - 0.011 15.5 1.2 0.027 14.3 0.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EDN92636.1 - 0.037 13.9 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 EDN92636.1 - 0.048 13.4 2.1 0.11 12.2 1.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein EamA PF00892.15 EDN92637.1 - 0.00031 20.7 12.3 0.00087 19.3 8.2 1.8 1 1 1 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EDN92637.1 - 0.00086 19.4 0.7 0.00086 19.4 0.5 1.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter PBP1_TM PF14812.1 EDN92637.1 - 0.0089 16.3 0.9 0.0089 16.3 0.6 3.1 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Ca_hom_mod PF14798.1 EDN92637.1 - 0.058 12.3 0.1 0.38 9.6 0.0 1.9 2 0 0 2 2 2 0 Calcium homeostasis modulator Oxidored_q6 PF01058.17 EDN92637.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit TPT PF03151.11 EDN92637.1 - 0.14 11.8 9.7 0.21 11.2 4.6 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family UPF0546 PF10639.4 EDN92637.1 - 0.15 11.8 2.5 0.31 10.8 1.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 zf-CCHC_5 PF14787.1 EDN92638.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger YlbD_coat PF14071.1 EDN92639.1 - 9.5 6.3 10.5 0.78 9.8 3.3 2.0 2 0 0 2 2 2 0 Putative coat protein TFIIA_gamma_C PF02751.9 EDN92641.1 - 9.3e-28 95.8 2.1 1.3e-27 95.3 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EDN92641.1 - 3e-17 61.9 0.5 4.2e-17 61.4 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 EDN92642.1 - 1.4e-26 92.1 27.7 8.8e-17 60.7 4.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Cation_efflux PF01545.16 EDN92642.1 - 2.2 7.2 12.0 0.033 13.2 0.8 2.4 1 1 1 2 2 2 0 Cation efflux family MoCF_biosynth PF00994.19 EDN92644.1 - 6.8e-57 190.9 1.5 4.4e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EDN92644.1 - 4.3e-35 120.4 3.2 7e-35 119.7 2.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EDN92644.1 - 1.3e-17 63.4 0.0 3.5e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) YajC PF02699.10 EDN92644.1 - 4.8 6.9 5.4 22 4.8 0.2 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit ATP_bind_1 PF03029.12 EDN92645.1 - 9.7e-74 247.8 0.0 1.3e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EDN92645.1 - 0.00066 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EDN92645.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EDN92645.1 - 0.027 14.4 0.0 0.1 12.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EDN92645.1 - 0.029 13.5 0.5 0.3 10.2 0.3 2.2 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.18 EDN92645.1 - 0.031 13.6 0.0 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EDN92645.1 - 0.032 13.3 0.2 0.081 12.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EDN92645.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EDN92645.1 - 0.14 13.0 2.8 0.41 11.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDN92645.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 EDN92646.1 - 6.2e-19 67.0 0.3 2.8e-05 23.8 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Collagen PF01391.13 EDN92647.1 - 0.0037 16.7 3.3 0.0085 15.6 2.3 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) KilA-N PF04383.8 EDN92648.1 - 0.0014 18.1 0.0 0.0095 15.5 0.0 2.1 1 1 1 2 2 2 1 KilA-N domain IER PF05760.7 EDN92648.1 - 1.6 8.5 17.5 3.4 7.5 12.1 1.5 1 1 0 1 1 1 0 Immediate early response protein (IER) Rho_GDI PF02115.12 EDN92649.1 - 2.6e-58 196.7 0.2 2.8e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EDN92650.1 - 1.2e-37 129.2 1.1 1.5e-37 128.9 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 EDN92651.1 - 7.6e-07 28.7 1.6 1.3e-06 28.0 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EDN92651.1 - 0.00022 20.6 1.1 0.0011 18.4 0.7 2.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN92651.1 - 0.052 13.2 0.9 0.095 12.3 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Adaptin_N PF01602.15 EDN92652.1 - 5.2e-103 345.1 0.0 7.1e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDN92652.1 - 3.3e-11 43.3 1.5 2.7e-05 24.3 0.0 4.8 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EDN92652.1 - 9.4e-09 34.6 0.1 0.2 11.8 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat Cohesin_HEAT PF12765.2 EDN92652.1 - 0.00024 21.0 0.0 0.54 10.2 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EDN92652.1 - 0.0044 17.4 7.9 0.024 15.1 0.0 4.8 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EDN92652.1 - 0.021 14.6 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Nuf2 PF03800.9 EDN92654.1 - 1.3e-47 161.4 0.2 3.3e-47 160.1 0.1 1.7 1 0 0 1 1 1 1 Nuf2 family Reo_sigmaC PF04582.7 EDN92654.1 - 0.32 10.1 6.2 0.3 10.2 2.6 1.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EDN92654.1 - 9.1 3.9 24.4 15 3.3 16.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_1 PF03184.14 EDN92655.1 - 8.8e-27 93.6 0.0 2e-26 92.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN92655.1 - 2.4e-07 30.4 1.0 3.7e-07 29.8 0.0 1.9 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain Phage_CI_repr PF07022.8 EDN92655.1 - 0.08 13.0 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Methyltransf_33 PF10017.4 EDN92656.1 - 2.7e-13 49.9 0.0 4.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EDN92656.1 - 6.1e-13 48.7 0.5 7.2e-12 45.2 0.4 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EDN92656.1 - 0.012 15.9 0.1 0.029 14.6 0.1 1.7 1 0 0 1 1 1 0 DinB superfamily CRA PF06589.6 EDN92657.1 - 1.3 8.2 3.9 0.48 9.7 0.2 2.0 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) CENP-H PF05837.7 EDN92657.1 - 1.4 9.1 6.6 5.3 7.2 0.7 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GATA PF00320.22 EDN92660.1 - 1.8e-31 107.1 17.6 4.8e-17 61.0 2.3 2.8 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EDN92660.1 - 6.2e-05 22.2 4.3 0.068 12.5 0.1 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EDN92660.1 - 0.00044 19.3 4.7 0.22 10.7 0.2 2.9 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EDN92660.1 - 0.0016 18.0 5.7 0.04 13.5 0.5 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain HypA PF01155.14 EDN92660.1 - 0.0042 16.7 1.8 0.65 9.6 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EDN92660.1 - 0.0074 16.2 2.2 1.6 8.7 0.1 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Ribosomal_L32p PF01783.18 EDN92660.1 - 0.067 13.3 6.0 2.2 8.5 1.2 4.0 2 2 0 2 2 2 0 Ribosomal L32p protein family Auto_anti-p27 PF06677.7 EDN92660.1 - 0.12 12.1 3.7 2.5 7.9 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 EDN92660.1 - 0.82 9.3 6.4 3.9 7.1 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.10 EDN92660.1 - 7.1 6.2 13.2 0.062 12.8 0.3 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger COPI_assoc PF08507.5 EDN92661.1 - 3.7e-14 52.5 1.2 3.9e-14 52.4 0.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3096 PF11295.3 EDN92661.1 - 0.0068 15.8 4.5 0.23 11.0 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3096) YtpI PF14007.1 EDN92661.1 - 0.0097 15.8 4.3 0.013 15.4 3.0 1.2 1 0 0 1 1 1 1 YtpI-like protein BPD_transp_2 PF02653.11 EDN92661.1 - 0.062 12.2 2.0 0.068 12.1 1.4 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component ExoD PF06055.7 EDN92661.1 - 0.1 11.6 1.8 0.13 11.4 1.3 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD DUF308 PF03729.8 EDN92661.1 - 1.8 8.6 9.8 30 4.7 6.9 2.0 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) DAO PF01266.19 EDN92662.1 - 3e-28 98.7 0.0 3.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN92662.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN92662.1 - 0.00046 19.3 1.2 0.00097 18.2 0.0 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 EDN92662.1 - 0.0018 17.1 0.0 0.0031 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN92662.1 - 0.046 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN92662.1 - 0.053 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EDN92662.1 - 0.061 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDN92662.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein OTU PF02338.14 EDN92663.1 - 3.3e-17 63.1 0.1 8.6e-17 61.8 0.1 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDN92663.1 - 0.0004 19.8 0.0 0.42 9.9 0.0 2.8 2 1 0 2 2 2 2 Peptidase C65 Otubain GCK PF07802.6 EDN92663.1 - 0.003 17.6 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 GCK domain Spp-24 PF07448.6 EDN92664.1 - 0.03 14.2 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) HRXXH PF13933.1 EDN92665.1 - 4.4e-100 334.1 0.1 5.4e-100 333.8 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 EDN92666.1 - 4.5e-38 131.0 19.0 7e-38 130.4 13.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter PepSY_TM_2 PF13703.1 EDN92667.1 - 0.082 13.0 5.2 0.081 13.1 3.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM helix CcmD PF04995.9 EDN92667.1 - 7.7 6.3 9.3 12 5.7 6.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) RCC1 PF00415.13 EDN92670.1 - 2.4e-50 168.5 0.4 5.4e-11 42.5 0.0 8.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN92670.1 - 2.3e-28 97.1 25.0 2.7e-09 36.3 0.2 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH_5 PF14567.1 EDN92670.1 - 0.022 14.2 0.0 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Thioredoxin PF00085.15 EDN92671.1 - 1e-26 92.6 0.0 2.2e-26 91.5 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EDN92671.1 - 6.9e-07 29.2 0.0 3.1e-05 24.0 0.0 2.4 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDN92671.1 - 3.1e-06 27.3 0.1 7.2e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EDN92671.1 - 0.00021 20.8 0.1 0.0024 17.4 0.1 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EDN92671.1 - 0.00077 19.0 0.0 0.0012 18.4 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EDN92671.1 - 0.0024 16.6 0.0 0.0028 16.4 0.0 1.1 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.16 EDN92671.1 - 0.0078 15.8 0.0 0.028 14.0 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA family Glutaredoxin PF00462.19 EDN92671.1 - 0.032 14.2 0.2 0.078 12.9 0.2 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.1 EDN92671.1 - 0.034 14.1 0.1 0.067 13.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Fer4_15 PF13459.1 EDN92671.1 - 0.11 13.1 0.1 0.26 11.8 0.1 1.8 1 1 0 1 1 1 0 4Fe-4S single cluster domain DRY_EERY PF09750.4 EDN92672.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 Alternative splicing regulator Spc97_Spc98 PF04130.8 EDN92676.1 - 9.3e-72 242.0 0.1 1.6e-71 241.2 0.0 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family Prefoldin PF02996.12 EDN92676.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit Exonuc_VII_L PF02601.10 EDN92677.1 - 0.002 17.4 0.1 0.0025 17.0 0.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4375 PF14300.1 EDN92677.1 - 0.022 14.7 0.3 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) U5_2-snRNA_bdg PF10597.4 EDN92677.1 - 0.054 13.0 0.1 0.15 11.6 0.0 1.7 1 1 1 2 2 2 0 U5-snRNA binding site 2 of PrP8 Ifi-6-16 PF06140.8 EDN92677.1 - 0.14 11.9 15.8 0.038 13.7 8.5 1.9 2 0 0 2 2 2 0 Interferon-induced 6-16 family DUF2809 PF10990.3 EDN92678.1 - 0.048 14.0 0.4 0.13 12.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) DnaJ PF00226.26 EDN92682.1 - 0.00051 19.7 0.1 0.012 15.3 0.1 2.7 1 1 0 1 1 1 1 DnaJ domain ParA PF10609.4 EDN92684.1 - 2.5e-35 120.2 0.0 8.6e-35 118.4 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EDN92684.1 - 1.8e-16 60.1 0.0 2.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EDN92684.1 - 8.5e-06 25.0 0.1 0.00057 19.0 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EDN92684.1 - 7.5e-05 22.7 0.0 0.00022 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EDN92684.1 - 0.00029 20.4 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN92684.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EDN92684.1 - 0.0013 17.8 0.0 0.0037 16.3 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ T2SE PF00437.15 EDN92684.1 - 0.0069 15.3 0.1 0.0099 14.8 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EDN92684.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EDN92684.1 - 0.018 14.7 0.2 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain Fer4_NifH PF00142.13 EDN92684.1 - 0.019 14.1 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirE PF05272.6 EDN92684.1 - 0.046 13.2 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Zn_Tnp_IS1595 PF12760.2 EDN92684.1 - 0.076 12.8 0.9 0.23 11.3 0.0 2.2 3 0 0 3 3 2 0 Transposase zinc-ribbon domain SRP54 PF00448.17 EDN92684.1 - 0.085 12.2 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EDN92684.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EDN92684.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN92684.1 - 0.14 13.0 0.2 0.49 11.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EDN92684.1 - 0.15 10.9 0.0 0.8 8.5 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_29 PF13555.1 EDN92684.1 - 0.17 11.4 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EDN92684.1 - 0.17 11.4 0.1 0.31 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain NUDIX PF00293.23 EDN92686.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2499 PF10693.4 EDN92687.1 - 0.022 14.7 0.1 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) Ion_trans PF00520.26 EDN92689.1 - 0.00033 19.9 24.1 0.0058 15.8 16.7 2.2 1 1 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.12 EDN92690.1 - 6.5e-111 368.6 0.2 1.5e-83 279.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EDN92690.1 - 3.3e-46 157.1 0.0 6.8e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EDN92690.1 - 5.2e-45 152.1 0.0 1.2e-44 150.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 EDN92690.1 - 1.8e-42 143.9 0.3 4.3e-42 142.7 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 EDN92690.1 - 5.7e-41 139.5 0.0 1.1e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EDN92690.1 - 8.9e-38 128.7 0.0 6.9e-21 74.4 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN92690.1 - 1e-33 116.6 0.1 6.4e-19 68.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EDN92690.1 - 1.7e-33 115.7 0.0 3.5e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EDN92690.1 - 8e-21 73.7 0.0 8.6e-20 70.4 0.0 2.9 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EDN92690.1 - 6.5e-16 58.3 0.2 1.1e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EDN92690.1 - 1.1e-15 57.2 0.1 5.6e-08 31.9 0.0 4.2 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDN92690.1 - 1e-13 51.0 0.0 4.8e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EDN92690.1 - 7.4e-07 28.8 0.2 2.8e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EDN92690.1 - 0.0001 22.1 0.2 0.2 11.5 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EDN92690.1 - 0.00029 20.3 0.0 0.087 12.2 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 EDN92690.1 - 0.0017 17.8 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EDN92690.1 - 0.015 14.8 0.2 0.88 9.1 0.0 2.9 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MFS_1 PF07690.11 EDN92691.1 - 2.8e-42 144.7 31.0 2.8e-42 144.7 21.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN92691.1 - 9.1e-13 47.5 10.0 9.1e-13 47.5 6.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 EDN92691.1 - 6.7 6.5 12.5 0.52 10.1 0.2 3.8 4 0 0 4 4 4 0 MFS_1 like family Fungal_trans PF04082.13 EDN92693.1 - 8.5e-12 44.4 1.3 8.5e-12 44.4 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EDN92693.1 - 4.9e-05 23.4 0.4 4.9e-05 23.4 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN92693.1 - 0.054 13.8 0.7 0.054 13.8 0.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.14 EDN92694.1 - 1.7e-27 96.4 0.0 2.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDN92694.1 - 7.5e-06 25.8 0.0 2.3e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EDN92694.1 - 0.00018 20.4 0.0 0.064 12.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 EDN92694.1 - 0.00055 20.2 0.0 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN92694.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN92694.1 - 0.0037 16.2 0.0 0.0068 15.3 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN92694.1 - 0.0095 15.8 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN92694.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EDN92694.1 - 0.047 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MRP-S35 PF10246.4 EDN92694.1 - 0.051 13.5 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Lycopene_cycl PF05834.7 EDN92694.1 - 0.086 11.7 0.0 0.37 9.6 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Abhydrolase_6 PF12697.2 EDN92695.1 - 1.7e-23 83.7 0.1 1.9e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN92695.1 - 5.8e-06 26.1 0.0 6.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN92695.1 - 0.0042 16.7 0.2 0.0081 15.7 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF1918 PF08940.6 EDN92695.1 - 0.081 12.2 0.7 0.87 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) LEF-8 PF04941.7 EDN92696.1 - 0.059 11.0 0.0 0.07 10.8 0.0 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) Benyvirus_14KDa PF07255.6 EDN92696.1 - 0.07 13.0 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Benyvirus 14KDa protein Metallophos PF00149.23 EDN92697.1 - 2.1e-05 23.9 1.0 0.00012 21.5 0.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN92697.1 - 0.003 17.4 0.1 0.0045 16.8 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain A_deamin PF02137.13 EDN92697.1 - 0.037 13.3 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain PGA_cap PF09587.5 EDN92697.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap AMP-binding PF00501.23 EDN92698.1 - 1.1e-80 271.1 0.0 1.8e-80 270.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EDN92698.1 - 6.6e-70 235.3 0.2 1e-37 129.6 0.0 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EDN92698.1 - 3.4e-18 65.6 0.5 2.3e-09 37.3 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EDN92698.1 - 0.00059 20.0 0.0 0.0034 17.6 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EDN92698.1 - 0.0011 19.8 0.3 0.003 18.4 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 EDN92699.1 - 1.4e-22 80.2 0.1 5.1e-22 78.4 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN92699.1 - 0.00013 20.9 0.0 0.0012 17.7 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EDN92699.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN92699.1 - 0.0022 17.9 0.0 0.0062 16.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EDN92699.1 - 0.023 14.0 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EDN92699.1 - 0.033 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EDN92699.1 - 0.045 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EDN92699.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN92699.1 - 0.093 11.5 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EDN92699.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EDN92699.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EDN92700.1 - 1.6e-27 96.7 0.0 1.8e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN92700.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EDN92700.1 - 0.00093 18.7 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EDN92700.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EDN92700.1 - 0.029 14.3 0.1 0.085 12.8 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EDN92700.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 EDN92701.1 - 1.4e-16 60.1 0.9 3.3e-16 58.9 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN92701.1 - 2.9e-08 33.4 8.2 5.8e-08 32.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c_4 PF13749.1 EDN92701.1 - 0.036 13.8 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 ATP-dependent DNA helicase recG C-terminal p450 PF00067.17 EDN92702.1 - 7.1e-35 120.4 0.0 9.4e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1180 PF06679.7 EDN92703.1 - 0.034 14.0 1.3 0.043 13.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PLRV_ORF5 PF01690.12 EDN92703.1 - 0.34 9.9 2.5 0.48 9.5 1.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WD40 PF00400.27 EDN92705.1 - 5.4e-37 124.3 6.3 5.4e-10 38.7 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EDN92705.1 - 6.4e-07 27.8 7.2 0.085 10.9 0.1 4.7 3 2 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDN92705.1 - 0.029 13.8 1.5 0.11 11.9 0.2 2.4 2 1 1 3 3 3 0 PQQ-like domain CM_2 PF01817.16 EDN92706.1 - 5.8e-08 32.7 0.0 0.00059 19.8 0.0 3.2 3 1 0 3 3 3 2 Chorismate mutase type II BCIP PF13862.1 EDN92707.1 - 7.7e-56 188.6 0.0 9.4e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SH3_9 PF14604.1 EDN92708.1 - 3.9e-06 26.3 0.0 1.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EDN92708.1 - 0.00016 20.9 0.1 0.00035 19.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF2668 PF10873.3 EDN92708.1 - 0.00078 19.6 0.1 0.0024 18.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF1183 PF06682.7 EDN92708.1 - 0.0057 16.3 4.5 0.0057 16.3 3.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) Mid2 PF04478.7 EDN92708.1 - 0.011 15.2 0.9 0.032 13.6 0.6 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gly-zipper_YMGG PF13441.1 EDN92708.1 - 0.014 14.9 12.8 0.045 13.2 0.8 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EDN92708.1 - 0.066 12.8 16.4 0.05 13.2 0.8 2.4 2 0 0 2 2 2 0 Glycine zipper MRAP PF15183.1 EDN92708.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2613 PF11021.3 EDN92708.1 - 0.23 11.1 4.2 1.9 8.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Yip1 PF04893.12 EDN92708.1 - 0.87 9.0 5.7 0.11 12.0 0.9 1.6 2 0 0 2 2 2 0 Yip1 domain Rick_17kDa_Anti PF05433.10 EDN92708.1 - 1 9.0 16.7 0.13 11.9 1.7 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EDN92708.1 - 3.8 7.2 13.6 0.35 10.5 1.2 2.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Pkinase PF00069.20 EDN92711.1 - 4.2e-23 81.8 0.0 8.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EDN92711.1 - 5.9e-14 51.3 8.5 4.8e-07 29.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EDN92711.1 - 6.7e-07 28.8 8.7 0.024 14.7 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 EDN92711.1 - 3.5e-06 26.2 0.0 5.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EDN92711.1 - 0.0022 18.2 0.7 4.9 7.5 0.0 3.6 2 1 2 4 4 4 3 HEAT repeats Kinase-like PF14531.1 EDN92711.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.1 EDN92711.1 - 0.048 14.1 1.7 1.4 9.5 0.1 3.9 5 0 0 5 5 5 0 HEAT-like repeat LRR_9 PF14580.1 EDN92712.1 - 3.6e-52 176.4 0.3 6.7e-52 175.5 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EDN92712.1 - 2.3e-13 49.4 6.2 7.1e-09 35.0 1.5 4.1 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN92712.1 - 3.2e-11 42.8 2.3 3.1e-10 39.6 0.5 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 EDN92712.1 - 0.0038 17.1 0.1 8.1 6.8 0.1 4.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 EDN92712.1 - 0.025 14.7 5.5 44 4.9 0.0 4.9 4 1 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EDN92712.1 - 0.16 12.0 7.6 6.3 7.2 0.1 4.8 5 1 1 6 6 6 0 Leucine Rich Repeat PspB PF06667.7 EDN92712.1 - 5.9 6.9 5.2 0.88 9.5 0.4 2.0 2 0 0 2 2 2 0 Phage shock protein B CBFD_NFYB_HMF PF00808.18 EDN92713.1 - 1.9e-10 40.6 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN92713.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NAD_binding_4 PF07993.7 EDN92715.1 - 2.1e-26 92.3 0.0 3.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN92715.1 - 9.1e-14 50.6 0.0 2.6e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EDN92715.1 - 2.9e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN92715.1 - 0.2 10.3 0.1 1.4 7.5 0.1 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.17 EDN92716.1 - 2.7e-25 87.7 0.6 2.5e-11 43.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN92716.1 - 5.7e-16 58.2 0.1 1.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN92716.1 - 1.1e-13 50.7 0.1 3.7e-10 39.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN92716.1 - 0.0065 16.1 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 EDN92716.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcipressin DUF45 PF01863.12 EDN92716.1 - 0.076 12.7 0.3 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 ATP-synt_D PF01813.12 EDN92717.1 - 9.5e-67 224.3 1.8 1.2e-66 224.0 1.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Iron_permease PF04120.7 EDN92717.1 - 0.63 9.6 3.3 1.3 8.6 1.1 2.0 2 0 0 2 2 2 0 Low affinity iron permease Nup54 PF13874.1 EDN92717.1 - 0.99 9.0 6.3 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 EDN92717.1 - 4.7 6.6 7.2 4.9 6.6 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_12 PF13424.1 EDN92718.1 - 5.6e-13 48.6 1.5 0.00034 20.4 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN92718.1 - 1.7e-09 37.4 13.5 1.4 9.7 0.0 10.0 11 1 1 12 12 11 2 Tetratricopeptide repeat Suf PF05843.9 EDN92718.1 - 2.2e-09 37.4 4.8 0.78 9.4 0.2 5.5 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EDN92718.1 - 1.2e-07 31.2 5.5 0.17 11.5 0.0 7.1 8 1 0 8 8 8 2 TPR repeat TPR_15 PF13429.1 EDN92718.1 - 3.9e-07 29.4 0.7 0.00021 20.4 0.4 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.1 EDN92718.1 - 9.6e-05 21.6 1.0 0.53 9.3 0.3 4.6 4 2 1 5 5 5 1 Soluble NSF attachment protein, SNAP Mad3_BUB1_I PF08311.7 EDN92718.1 - 0.00016 21.4 10.6 0.58 9.9 0.1 6.1 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_16 PF13432.1 EDN92718.1 - 0.00017 22.1 14.1 0.0012 19.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN92718.1 - 0.0018 17.8 6.9 0.73 9.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN92718.1 - 0.0022 17.7 15.8 2.4 8.2 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDN92718.1 - 0.088 12.0 0.0 0.47 9.7 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.1 EDN92718.1 - 2.5 8.5 6.7 19 5.8 0.0 5.7 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN92718.1 - 4.6 7.3 7.6 76 3.4 0.5 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Asp PF00026.18 EDN92720.1 - 0.0098 15.1 0.2 3.6 6.7 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease LigA PF07746.6 EDN92721.1 - 0.09 12.7 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit F-box PF00646.28 EDN92722.1 - 1.7e-08 33.8 0.3 4.8e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EDN92722.1 - 2.1e-08 33.7 0.2 4e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like DHHA2 PF02833.9 EDN92723.1 - 2.8e-29 101.8 0.0 5e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EDN92723.1 - 1.1e-07 31.6 0.0 4.6e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 DHH family DUF3384 PF11864.3 EDN92723.1 - 0.044 12.2 0.0 0.061 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Lon_C PF05362.8 EDN92726.1 - 2.4e-24 85.8 0.1 2.8e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 EDN92726.1 - 0.0008 18.9 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase TFIIA PF03153.8 EDN92733.1 - 0.09 12.6 6.2 0.16 11.8 4.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MOR2-PAG1_C PF14225.1 EDN92736.1 - 2.2e-77 260.3 5.7 1.3e-56 192.2 0.0 3.2 3 1 1 4 4 4 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EDN92736.1 - 3.7e-26 91.1 0.8 6.4e-12 43.9 0.0 3.1 3 0 0 3 3 3 2 Cell morphogenesis central region MRP_L53 PF10780.4 EDN92736.1 - 0.084 12.8 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 MOR2-PAG1_N PF14222.1 EDN92737.1 - 2e-228 759.5 0.0 2.6e-228 759.2 0.0 1.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal FAD_binding_1 PF00667.15 EDN92739.1 - 3.8e-60 203.0 0.0 6e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EDN92739.1 - 2.3e-31 108.7 3.2 4.9e-31 107.6 2.3 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDN92739.1 - 2.3e-22 79.6 0.2 2.9e-21 76.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EDN92739.1 - 0.041 13.8 0.0 0.2 11.6 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EDN92741.1 - 1.8e-22 78.7 0.0 3.2e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN92741.1 - 1.3e-14 53.9 0.0 5.9e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN92741.1 - 0.0096 15.7 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 EDN92742.1 - 3.3e-41 140.7 0.1 8.3e-41 139.4 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EDN92742.1 - 2.7e-31 107.4 0.1 5.1e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EDN92742.1 - 7.2e-08 32.4 0.1 0.00054 19.7 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN92742.1 - 2.3e-06 26.8 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.7 EDN92742.1 - 0.063 12.5 13.0 0.088 12.0 9.0 1.1 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.9 EDN92742.1 - 0.29 11.2 23.4 0.58 10.3 16.3 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Daxx PF03344.10 EDN92742.1 - 1 7.7 18.4 1.4 7.3 12.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EDN92742.1 - 8.4 4.2 10.6 11 3.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PC_rep PF01851.17 EDN92743.1 - 3.1e-24 83.7 20.9 4.2e-08 32.9 0.1 9.5 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDN92743.1 - 2e-09 37.5 0.7 0.0015 18.8 0.0 4.2 3 2 1 4 4 4 2 HEAT repeats FEZ PF07763.8 EDN92743.1 - 0.077 12.6 3.8 0.14 11.8 0.4 2.3 2 0 0 2 2 2 0 FEZ-like protein DNA_mis_repair PF01119.14 EDN92744.1 - 7.4e-32 109.3 0.0 1.3e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EDN92744.1 - 2.9e-15 56.1 0.0 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN92744.1 - 1.7e-10 40.5 0.0 3.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMC_oxred_N PF00732.14 EDN92745.1 - 1.4e-45 155.7 0.0 2.1e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN92745.1 - 2.2e-33 115.5 0.0 5.1e-32 111.1 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EDN92745.1 - 0.001 19.0 0.1 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN92745.1 - 0.012 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN92745.1 - 0.017 14.0 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EDN92745.1 - 0.21 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF202 PF02656.10 EDN92746.1 - 7.6e-21 74.1 2.8 2.9e-20 72.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EDN92746.1 - 0.21 11.6 0.0 0.21 11.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV LHC PF00556.15 EDN92746.1 - 0.61 9.9 0.1 0.61 9.9 0.1 2.3 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit DUF3112 PF11309.3 EDN92746.1 - 0.86 9.3 4.5 1.3 8.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF2976 PF11190.3 EDN92746.1 - 0.93 9.0 3.6 0.43 10.1 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) MatE PF01554.13 EDN92747.1 - 5e-53 179.0 27.2 7.1e-28 97.2 6.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EDN92747.1 - 8.3e-05 22.4 8.0 8.3e-05 22.4 5.6 3.8 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain PHP PF02811.14 EDN92748.1 - 8.2e-15 55.0 0.0 1.5e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 PHP domain GMC_oxred_N PF00732.14 EDN92751.1 - 1.8e-06 27.3 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase ACPS PF01648.15 EDN92752.1 - 1.8e-14 53.5 0.1 6.6e-09 35.5 0.0 2.8 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily zf-RanBP PF00641.13 EDN92752.1 - 0.0065 15.5 2.3 0.016 14.2 1.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others S-antigen PF05756.6 EDN92752.1 - 1.2 9.1 6.8 2.8 7.9 4.7 1.6 1 0 0 1 1 1 0 S-antigen protein GOLD_2 PF13897.1 EDN92752.1 - 6.1 7.0 6.6 0.44 10.7 0.8 1.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF1774 PF08611.5 EDN92753.1 - 0.071 13.2 0.0 0.071 13.2 0.0 3.1 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) FixQ PF05545.6 EDN92753.1 - 1 9.0 6.7 0.12 11.9 0.4 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_M28 PF04389.12 EDN92754.1 - 4.5e-28 98.2 0.1 1.1e-27 96.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDN92754.1 - 2.1e-06 27.4 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 EDN92755.1 - 7.2e-26 90.6 4.3 1.3e-25 89.9 3.0 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EDN92755.1 - 0.00047 19.7 1.1 0.0026 17.4 0.0 2.5 2 1 1 3 3 3 1 R3H domain OmpH PF03938.9 EDN92755.1 - 0.38 10.6 3.2 0.46 10.3 1.7 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NinG PF05766.7 EDN92755.1 - 7.7 6.2 9.1 0.9 9.2 2.2 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein AFG1_ATPase PF03969.11 EDN92756.1 - 1.1e-93 313.9 0.0 1.4e-88 297.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EDN92756.1 - 8.4e-06 25.8 0.1 0.01 15.8 0.0 2.7 2 1 0 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.13 EDN92756.1 - 0.0016 18.1 0.2 0.18 11.4 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 EDN92756.1 - 0.0021 18.2 0.0 0.0083 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN92756.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EDN92756.1 - 0.0063 16.1 0.0 0.024 14.2 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA PF00004.24 EDN92756.1 - 0.0078 16.4 0.3 0.039 14.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDN92756.1 - 0.02 14.6 0.0 0.058 13.0 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EDN92756.1 - 0.064 13.3 0.0 0.58 10.2 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EDN92756.1 - 0.068 13.3 0.3 0.28 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EDN92756.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 EDN92756.1 - 0.12 11.9 0.5 13 5.2 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein S1-P1_nuclease PF02265.11 EDN92757.1 - 1.7e-64 217.8 0.0 2e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease RNA_pol PF00940.14 EDN92759.1 - 1.9e-160 533.8 0.0 2.8e-160 533.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EDN92759.1 - 1.6e-79 267.4 0.1 2.7e-79 266.7 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Myb_Cef PF11831.3 EDN92761.1 - 2.3e-67 226.5 1.5 2.3e-67 226.5 1.0 2.8 2 0 0 2 2 2 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EDN92761.1 - 1.7e-20 72.8 6.4 7.5e-14 51.5 1.4 3.9 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN92761.1 - 1.3e-19 70.0 6.8 4.1e-09 36.3 0.3 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EDN92761.1 - 3.1 7.7 6.8 0.88 9.5 0.0 3.2 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Hexokinase_2 PF03727.11 EDN92762.1 - 1.9e-23 82.9 0.0 2.9e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 EDN92762.1 - 4.3e-12 45.7 0.0 5.2e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Hexokinase GILT PF03227.11 EDN92763.1 - 4e-09 36.2 0.0 7.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Fungal_trans PF04082.13 EDN92766.1 - 2.9e-41 141.0 0.0 4.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN92766.1 - 4.2e-09 36.1 7.1 8.4e-09 35.1 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind PF01588.15 EDN92767.1 - 1.4e-22 79.3 0.6 1.8e-21 75.7 0.4 2.4 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EDN92767.1 - 2e-08 34.6 0.2 5.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN92767.1 - 2e-05 24.3 0.0 5.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN92767.1 - 0.00034 20.5 0.1 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Rotamase_2 PF13145.1 EDN92767.1 - 0.18 12.4 11.5 0.6 10.7 8.0 1.9 1 1 0 1 1 1 0 PPIC-type PPIASE domain DUF3323 PF11796.3 EDN92767.1 - 1.5 8.0 7.0 2 7.7 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) CHASE3 PF05227.8 EDN92768.1 - 0.0027 17.3 7.6 0.13 11.9 0.1 3.2 3 0 0 3 3 3 2 CHASE3 domain Rep_4 PF05797.6 EDN92768.1 - 0.5 9.0 3.3 2 7.0 0.6 2.2 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) ORF6C PF10552.4 EDN92768.1 - 0.64 9.7 3.5 29 4.4 1.6 2.3 2 0 0 2 2 2 0 ORF6C domain INCENP_ARK-bind PF03941.10 EDN92768.1 - 1.4 8.8 4.7 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Pyridox_oxase_2 PF12766.2 EDN92769.1 - 2.2e-13 50.3 0.0 4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_28 PF00295.12 EDN92770.1 - 4.6e-45 154.0 4.1 4.7e-44 150.6 2.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 HATPase_c PF02518.21 EDN92772.1 - 1.2e-24 86.1 0.0 2.4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EDN92772.1 - 3.1e-23 82.1 0.0 1.3e-10 41.5 0.0 3.6 3 0 0 3 3 3 2 PAS domain Response_reg PF00072.19 EDN92772.1 - 1.1e-19 70.5 0.3 1e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain PAS_4 PF08448.5 EDN92772.1 - 9.9e-13 48.0 0.0 6.2e-05 23.0 0.0 3.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EDN92772.1 - 6.6e-10 38.7 0.0 0.00026 20.7 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EDN92772.1 - 1e-09 37.8 0.0 0.0027 17.5 0.0 3.2 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 EDN92772.1 - 3.1e-08 33.4 0.2 1.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.2 EDN92772.1 - 2.2e-05 24.4 0.0 0.21 11.6 0.0 3.8 4 0 0 4 4 4 2 PAS fold GAF_3 PF13492.1 EDN92772.1 - 6e-05 23.1 0.0 0.00032 20.8 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.1 EDN92772.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 GAF domain HATPase_c_3 PF13589.1 EDN92772.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Formyl_trans_C PF02911.13 EDN92772.1 - 0.15 12.1 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain GHMP_kinases_N PF00288.21 EDN92773.1 - 1.2e-14 54.0 0.6 3e-14 52.8 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDN92773.1 - 2.5e-07 30.8 0.0 4.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_2 PF13041.1 EDN92774.1 - 1.8e-52 175.0 10.1 1.2e-08 34.7 0.0 14.1 10 3 5 16 16 16 12 PPR repeat family PPR_3 PF13812.1 EDN92774.1 - 3.5e-28 95.4 19.9 0.0011 19.0 0.0 16.1 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR PF01535.15 EDN92774.1 - 2.4e-26 89.8 23.8 0.0002 21.0 0.0 14.0 17 1 0 17 17 17 5 PPR repeat PPR_1 PF12854.2 EDN92774.1 - 2.5e-25 87.6 0.1 5.9e-08 32.0 0.0 10.9 11 0 0 11 11 11 4 PPR repeat TPR_14 PF13428.1 EDN92774.1 - 0.00012 22.3 2.5 56 4.7 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat RPM2 PF08579.6 EDN92774.1 - 0.0031 17.6 0.0 0.84 9.7 0.0 4.5 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EDN92774.1 - 0.099 11.4 0.0 3.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway XPG_I PF00867.13 EDN92775.1 - 2.3e-21 75.6 0.0 7.2e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDN92775.1 - 2.7e-05 24.3 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDN92775.1 - 0.046 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing GLTT PF01744.15 EDN92775.1 - 0.34 10.3 5.6 0.68 9.4 3.9 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) XPG_I PF00867.13 EDN92777.1 - 2.4e-19 69.1 0.0 4.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDN92777.1 - 0.0059 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDN92777.1 - 0.0062 16.0 0.1 0.0096 15.4 0.0 1.3 1 1 0 1 1 1 1 XPG domain containing p450 PF00067.17 EDN92778.1 - 3e-45 154.6 0.0 3.9e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIP PF03583.9 EDN92780.1 - 1.2e-70 238.0 0.0 1.5e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Glyoxalase_5 PF14696.1 EDN92780.1 - 0.0095 15.8 0.0 0.023 14.6 0.0 1.6 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FAD_binding_4 PF01565.18 EDN92781.1 - 4.8e-22 77.9 2.9 7.2e-22 77.3 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN92781.1 - 0.00033 20.4 0.1 0.00076 19.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like UCR_TM PF02921.9 EDN92782.1 - 3.5e-21 75.1 2.0 6.4e-21 74.3 1.4 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EDN92782.1 - 8.9e-19 66.8 0.1 1.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Cpn60_TCP1 PF00118.19 EDN92783.1 - 1.2e-132 442.9 14.2 1.5e-132 442.7 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_Eps PF04627.8 EDN92783.1 - 7.5 6.1 5.8 6 6.5 0.1 3.4 4 0 0 4 4 4 0 Mitochondrial ATP synthase epsilon chain tRNA-synt_2b PF00587.20 EDN92784.1 - 3.1e-20 72.4 0.0 5.3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN92784.1 - 1.4e-17 63.3 0.0 2.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 EDN92784.1 - 7.5e-12 44.9 0.4 1.5e-11 43.9 0.3 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal SpoVR PF04293.8 EDN92785.1 - 0.12 10.7 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 SpoVR like protein Ank_2 PF12796.2 EDN92786.1 - 1.1e-20 73.6 0.1 5.8e-10 39.3 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN92786.1 - 3e-18 64.6 0.0 1.8e-07 30.6 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EDN92786.1 - 1.2e-13 51.1 0.0 1.2e-05 25.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN92786.1 - 2e-12 46.8 0.0 0.00019 21.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN92786.1 - 6.3e-12 44.5 0.1 0.0013 18.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PUA PF01472.15 EDN92787.1 - 3.4e-15 55.5 1.2 7.5e-15 54.4 0.8 1.6 1 1 0 1 1 1 1 PUA domain AA_kinase PF00696.23 EDN92787.1 - 1.9e-08 34.1 0.1 2.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family Peptidase_M76 PF09768.4 EDN92788.1 - 2.4e-71 238.7 3.8 2.9e-71 238.4 2.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family DUF2315 PF10231.4 EDN92788.1 - 0.02 14.7 0.6 0.047 13.5 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) Peptidase_M13 PF01431.16 EDN92788.1 - 0.094 11.8 0.2 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M13 SprT-like PF10263.4 EDN92788.1 - 0.16 11.5 9.8 0.1 12.2 4.5 2.2 1 1 1 2 2 2 0 SprT-like family Pkinase PF00069.20 EDN92789.1 - 4.6e-73 245.5 0.0 6.3e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN92789.1 - 1.2e-44 152.3 0.0 1.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN92789.1 - 5.4e-09 35.4 0.0 8.2e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN92789.1 - 0.00012 21.1 0.1 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDN92789.1 - 0.0056 16.0 0.1 0.012 14.9 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EDN92789.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN92789.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TIP41 PF04176.8 EDN92790.1 - 2.2e-77 258.4 0.3 2.7e-77 258.1 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family Toxin_YhaV PF11663.3 EDN92790.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Toxin with endonuclease activity YhaV p450 PF00067.17 EDN92795.1 - 4.8e-62 209.9 0.0 1.3e-48 165.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 SET PF00856.23 EDN92797.1 - 3.7e-15 56.6 1.0 1e-12 48.6 0.3 2.6 3 0 0 3 3 3 2 SET domain Transp_cyt_pur PF02133.10 EDN92799.1 - 3.7e-47 160.8 16.3 4.3e-47 160.6 11.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 EDN92800.1 - 8.2e-24 83.9 9.9 9.5e-24 83.7 6.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4260 PF14079.1 EDN92800.1 - 0.66 9.8 4.2 1.1 9.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) MFS_1 PF07690.11 EDN92802.1 - 1.1e-13 50.6 16.2 1.3e-13 50.3 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1700 PF08006.6 EDN92802.1 - 0.59 9.4 7.6 0.95 8.7 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MFS_1 PF07690.11 EDN92803.1 - 0.0013 17.5 3.8 0.0019 16.9 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauE PF01925.14 EDN92803.1 - 0.076 12.4 5.9 0.15 11.4 4.1 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE EIIBC-GUT_C PF07663.6 EDN92803.1 - 0.39 10.8 7.3 1.3 9.2 1.9 2.3 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus Bac_export_1 PF01311.15 EDN92803.1 - 4.8 6.3 6.6 7.8 5.6 0.4 2.0 1 1 1 2 2 2 0 Bacterial export proteins, family 1 Rhomboid PF01694.17 EDN92804.1 - 0.0062 16.5 1.8 0.0069 16.4 1.3 1.1 1 0 0 1 1 1 1 Rhomboid family Ribonuclease_T2 PF00445.13 EDN92808.1 - 2e-24 86.2 0.0 2.3e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family p450 PF00067.17 EDN92812.1 - 4.4e-38 130.9 0.5 1.1e-37 129.7 0.3 1.5 1 1 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EDN92813.1 - 1.4e-32 112.5 0.1 1.1e-25 90.0 0.0 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_psq PF05225.11 EDN92813.1 - 6e-11 41.7 0.7 4.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN92813.1 - 1.8e-07 30.8 0.1 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_37 PF13744.1 EDN92813.1 - 0.032 14.0 0.2 0.085 12.6 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDN92813.1 - 0.098 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 NUMOD1 domain Homeobox_KN PF05920.6 EDN92816.1 - 2.9e-18 65.2 0.5 6.7e-18 64.1 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EDN92816.1 - 9.1e-07 28.4 0.3 1.7e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain RtcR PF06956.6 EDN92816.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Glyco_tran_WecB PF03808.8 EDN92821.1 - 0.064 12.6 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DDE_1 PF03184.14 EDN92822.1 - 1e-50 171.9 0.0 5.3e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN92822.1 - 5.8e-13 48.8 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN92822.1 - 1.3e-12 47.0 3.2 7e-12 44.7 0.4 2.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN92822.1 - 4.4e-11 42.4 0.3 1.4e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN92822.1 - 0.0083 16.2 0.1 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 EDN92822.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Acyltransferase PF01553.16 EDN92823.1 - 0.03 13.7 0.0 0.085 12.2 0.0 1.7 2 1 0 2 2 2 0 Acyltransferase DUF3538 PF12057.3 EDN92823.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) CAP59_mtransfer PF11735.3 EDN92826.1 - 1.9e-31 109.1 0.1 1.5e-30 106.2 0.1 2.0 1 1 1 2 2 2 2 Cryptococcal mannosyltransferase 1 Glyco_hydro_18 PF00704.23 EDN92830.1 - 1.2e-17 64.3 5.6 9e-17 61.5 0.6 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EDN92830.1 - 3e-12 45.9 9.0 6.6e-12 44.8 6.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_4 PF01565.18 EDN92831.1 - 2e-19 69.4 1.5 1e-18 67.1 1.0 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN92831.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like HTH_Tnp_Tc5 PF03221.11 EDN92832.1 - 1.4e-07 31.1 0.0 3.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Ricin_B_lectin PF00652.17 EDN92833.1 - 1.6e-12 47.5 0.6 1.3e-05 25.2 0.1 4.3 2 2 1 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EDN92833.1 - 1.8e-07 30.6 5.8 0.0003 20.1 0.1 3.2 2 1 2 4 4 4 2 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 EDN92833.1 - 0.00063 20.0 0.0 0.37 11.1 0.0 2.8 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Med3 PF11593.3 EDN92833.1 - 1.9 7.6 15.3 2.8 7.0 10.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn60_TCP1 PF00118.19 EDN92834.1 - 2.6e-135 451.7 5.4 3e-135 451.6 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMG_box PF00505.14 EDN92835.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN92835.1 - 0.03 14.6 0.0 0.083 13.2 0.0 1.7 2 0 0 2 2 2 0 HMG-box domain DUF2280 PF10045.4 EDN92835.1 - 0.079 12.8 0.2 9.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Atg14 PF10186.4 EDN92835.1 - 0.2 10.5 3.2 0.37 9.7 2.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EDN92835.1 - 0.38 11.1 2.6 0.46 10.8 0.5 2.1 2 1 0 2 2 2 0 SlyX DUF155 PF02582.9 EDN92836.1 - 2e-56 190.6 0.3 3.2e-56 189.9 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 EDN92836.1 - 0.026 14.7 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Herpes_UL92 PF03048.9 EDN92838.1 - 0.072 12.6 0.2 0.083 12.4 0.1 1.0 1 0 0 1 1 1 0 UL92 family DPBB_1 PF03330.13 EDN92841.1 - 3.6e-11 42.9 0.1 5.4e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDN92841.1 - 0.00018 21.1 0.1 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EDN92841.1 - 0.00079 19.4 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Cerato-platanin PRK PF00485.13 EDN92842.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Abhydrolase_3 PF07859.8 EDN92846.1 - 3.5e-22 79.0 0.0 5.1e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN92846.1 - 7.2e-20 70.9 0.0 9e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EDN92846.1 - 0.16 10.6 0.2 9 4.8 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family SET PF00856.23 EDN92847.1 - 9e-12 45.5 0.0 6.2e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EDN92847.1 - 0.024 15.0 0.0 0.7 10.3 0.0 2.3 2 0 0 2 2 2 0 SAF domain Abhydrolase_3 PF07859.8 EDN92848.1 - 8.3e-23 81.0 0.0 1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 EDN92848.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Acetyltransf_2 PF00797.12 EDN92849.1 - 2.3e-07 30.6 0.1 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 2 N-acetyltransferase Fungal_trans PF04082.13 EDN92850.1 - 2.2e-10 39.8 0.0 2.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PH_10 PF15411.1 EDN92851.1 - 2.8e-24 85.5 0.3 6e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EDN92851.1 - 4.4e-12 45.9 0.1 3.2e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EDN92851.1 - 9e-09 35.2 0.1 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EDN92851.1 - 3.8e-08 33.0 5.5 7.3e-08 32.1 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN92851.1 - 5.8e-05 22.7 5.3 0.0001 21.9 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN92851.1 - 0.00022 20.8 1.8 0.00038 20.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN92851.1 - 0.00026 20.9 4.8 0.00046 20.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN92851.1 - 0.00065 19.3 5.4 0.0012 18.4 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN92851.1 - 0.0018 18.3 1.7 0.0035 17.3 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger PH PF00169.24 EDN92851.1 - 0.011 15.8 0.2 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.6 EDN92851.1 - 0.15 11.9 0.3 0.37 10.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 EDN92851.1 - 0.15 12.0 4.8 0.29 11.1 3.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EDN92851.1 - 0.75 9.4 3.5 1.3 8.6 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4222 PF13973.1 EDN92855.1 - 0.08 12.3 0.1 0.098 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) SapB_2 PF03489.12 EDN92857.1 - 0.043 13.8 0.2 0.057 13.4 0.1 1.2 1 0 0 1 1 1 0 Saposin-like type B, region 2 BofC_C PF08955.5 EDN92861.1 - 0.02 14.9 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 BofC C-terminal domain TRAPPC9-Trs120 PF08626.6 EDN92862.1 - 2.3e-122 409.5 0.0 4.2e-122 408.6 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 EDN92862.1 - 0.14 12.1 0.1 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.6 EDN92863.1 - 2.8e-09 34.9 0.0 2.8e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Zn_clus PF00172.13 EDN92864.1 - 3.7e-07 29.9 6.0 3.7e-07 29.9 4.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 EDN92864.1 - 0.37 10.3 2.7 0.59 9.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Elong_Iki1 PF10483.4 EDN92866.1 - 4.8e-92 308.2 0.0 5.6e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Sec8_exocyst PF04048.9 EDN92867.1 - 1.1e-27 96.4 0.3 5.9e-22 77.8 0.0 3.0 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain Plectin PF00681.15 EDN92867.1 - 0.024 14.1 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Plectin repeat Actin PF00022.14 EDN92868.1 - 6.2e-159 528.6 0.0 7.1e-159 528.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EDN92868.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EDN92869.1 - 2.6e-31 107.9 1.7 4.4e-31 107.2 0.2 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EDN92869.1 - 9.1e-11 41.8 1.2 3.2e-05 24.1 0.1 2.6 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 EDN92869.1 - 4.6e-09 35.7 0.3 0.0045 16.7 0.0 3.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EDN92869.1 - 2e-06 28.0 0.1 0.00092 19.6 0.0 3.3 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EDN92869.1 - 3.2e-06 26.7 0.1 0.0096 15.9 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat RICTOR_V PF14668.1 EDN92869.1 - 0.03 14.2 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 EDN92869.1 - 0.033 14.0 0.3 0.33 10.8 0.1 2.1 1 1 1 2 2 2 0 V-ATPase subunit H V-ATPase_H_N PF03224.9 EDN92869.1 - 0.063 12.3 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Rota_VP2 PF05087.7 EDN92869.1 - 0.075 10.9 0.1 0.091 10.6 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF2296 PF10058.4 EDN92870.1 - 0.099 12.4 0.1 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) p450 PF00067.17 EDN92872.1 - 9.4e-49 166.1 0.2 2e-46 158.5 0.2 2.1 1 1 0 1 1 1 1 Cytochrome P450 SMI1_KNR4 PF09346.5 EDN92873.1 - 1.2e-33 115.9 0.0 2.1e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF3657 PF12394.3 EDN92874.1 - 0.0046 16.9 0.1 0.0055 16.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) UPF0220 PF05255.6 EDN92876.1 - 1.9e-64 215.9 0.9 2.1e-64 215.7 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Phosphodiest PF01663.17 EDN92877.1 - 3.4e-14 52.9 0.4 6.1e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDN92877.1 - 5.3e-06 26.0 1.4 9e-06 25.2 1.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EDN92877.1 - 1.7e-05 24.1 0.1 0.00011 21.5 0.0 2.3 2 1 0 2 2 2 1 Sulfatase DUF1777 PF08648.7 EDN92878.1 - 1.8e-20 73.4 58.0 1.8e-20 73.4 40.2 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Glyco_hydro_63 PF03200.11 EDN92879.1 - 7.7e-244 811.2 0.1 8.7e-243 807.7 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EDN92879.1 - 0.00019 20.2 0.1 0.00031 19.5 0.1 1.2 1 0 0 1 1 1 1 Trehalase COesterase PF00135.23 EDN92882.1 - 6.4e-80 269.3 0.5 9.6e-80 268.7 0.4 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN92882.1 - 7e-07 29.0 0.3 1.4e-05 24.8 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-H2C2_2 PF13465.1 EDN92885.1 - 8.1e-17 60.6 18.6 7.1e-06 26.0 0.3 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDN92885.1 - 1.8e-14 53.0 20.1 0.00018 21.6 0.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN92885.1 - 2.1e-10 40.1 18.0 0.00063 19.8 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EDN92885.1 - 1.6e-05 24.9 1.0 1.4 9.1 0.0 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN92885.1 - 0.079 13.1 3.0 0.56 10.4 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EDN92885.1 - 0.92 9.9 8.4 1.7 9.1 1.1 2.6 2 0 0 2 2 2 0 TRAF-type zinc finger CHORD PF04968.7 EDN92885.1 - 1.8 8.8 5.2 3.7 7.8 0.2 3.0 3 1 0 3 3 3 0 CHORD zf-C2H2_6 PF13912.1 EDN92885.1 - 8.5 6.4 8.5 0.38 10.7 0.1 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger Urm1 PF09138.6 EDN92886.1 - 1.9e-34 117.6 0.0 2.2e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EDN92886.1 - 0.0096 16.3 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family WD40 PF00400.27 EDN92887.1 - 4.9e-60 197.3 25.8 1e-08 34.6 0.2 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat SR-25 PF10500.4 EDN92887.1 - 0.017 14.6 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BBS2_Mid PF14783.1 EDN92887.1 - 0.19 11.4 2.8 5 6.9 0.0 4.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 EDN92887.1 - 0.25 11.0 2.4 24 4.7 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.22 EDN92888.1 - 2.7e-15 56.8 0.1 1.9e-14 54.1 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN92888.1 - 2.1e-13 50.8 0.6 2.4e-10 40.8 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EDN92888.1 - 3.6e-08 32.8 0.0 0.00026 20.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EDN92888.1 - 5.4e-05 22.5 0.0 0.031 13.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN92888.1 - 0.00072 19.0 0.2 0.0013 18.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EDN92888.1 - 0.0008 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EDN92888.1 - 0.00083 16.8 0.2 0.0011 16.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EDN92888.1 - 0.01 16.2 0.2 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN92888.1 - 0.011 15.6 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDN92888.1 - 0.011 15.9 0.1 0.09 12.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EDN92888.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 EDN92888.1 - 0.029 13.5 0.5 0.093 11.9 0.4 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_25 PF13481.1 EDN92888.1 - 0.031 13.6 0.4 0.083 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN92888.1 - 0.043 13.7 0.5 0.08 12.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain NAAA-beta PF15508.1 EDN92888.1 - 0.044 14.1 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA_17 PF13207.1 EDN92888.1 - 0.046 14.5 1.1 0.1 13.4 0.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDN92888.1 - 0.061 13.4 0.6 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EDN92888.1 - 0.08 12.7 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_10 PF12846.2 EDN92888.1 - 0.094 12.1 0.1 0.27 10.6 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EDN92888.1 - 0.1 12.5 2.2 0.11 12.4 0.2 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 EDN92888.1 - 0.16 10.4 0.1 0.22 9.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN92888.1 - 0.16 11.6 0.5 0.97 9.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EDN92888.1 - 0.16 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 EDN92888.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MBOAT_2 PF13813.1 EDN92892.1 - 1.2e-15 57.2 2.9 2.5e-15 56.2 2.0 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PDR_assoc PF08370.6 EDN92892.1 - 0.0083 15.6 1.1 0.02 14.3 0.8 1.7 1 0 0 1 1 1 1 Plant PDR ABC transporter associated Lysine_decarbox PF03641.9 EDN92893.1 - 9.6e-30 103.1 0.0 1.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EDN92894.1 - 1.4e-51 174.4 0.0 1.8e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN92894.1 - 3.6e-11 42.1 0.2 7.4e-11 41.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 EDN92895.1 - 8.3e-43 144.9 8.9 9.2e-43 144.8 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Chorismate_bind PF00425.13 EDN92896.1 - 2.7e-63 213.7 0.0 6e-35 120.8 0.0 2.6 1 1 1 2 2 2 2 chorismate binding enzyme GATase PF00117.23 EDN92896.1 - 1.7e-23 83.1 0.0 8.6e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EDN92896.1 - 1.1e-17 64.3 0.0 2.8e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EDN92896.1 - 1.4e-05 24.6 0.1 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 p450 PF00067.17 EDN92900.1 - 0.0028 16.2 0.0 0.0029 16.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Translat_reg PF01818.12 EDN92900.1 - 0.093 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage translational regulator Longin PF13774.1 EDN92902.1 - 1.7e-27 94.7 0.2 3.1e-27 93.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDN92902.1 - 2.9e-16 58.8 0.7 1.1e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 EDN92902.1 - 0.053 13.3 1.3 0.097 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 EDN92902.1 - 0.064 13.6 1.7 11 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 EDN92903.1 - 0.0022 17.7 0.0 0.011 15.4 0.0 2.0 1 1 0 2 2 2 1 Asx homology domain ECH PF00378.15 EDN92906.1 - 1.2e-30 106.4 0.0 1.8e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Diphtheria_T PF02764.9 EDN92906.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain AMP-binding PF00501.23 EDN92909.1 - 0.0022 16.4 0.0 0.0038 15.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.17 EDN92910.1 - 0.0003 20.3 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EDN92910.1 - 0.043 13.8 0.4 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding RRM_5 PF13893.1 EDN92910.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4451 PF14616.1 EDN92911.1 - 0.032 13.9 0.1 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) PPR_2 PF13041.1 EDN92912.1 - 2.5e-20 72.2 0.0 1.8e-14 53.4 0.0 4.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EDN92912.1 - 1.8e-05 24.6 0.4 14 6.2 0.0 5.7 6 1 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EDN92912.1 - 0.0064 16.3 5.7 0.14 12.2 0.0 4.7 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 EDN92912.1 - 0.008 15.6 0.4 17 4.9 0.0 4.2 4 0 0 4 4 4 1 PPR repeat DNA_pol_B PF00136.16 EDN92913.1 - 4.1e-111 372.0 5.9 6.3e-111 371.4 4.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EDN92913.1 - 3.9e-65 218.7 4.2 6.9e-65 217.9 2.9 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EDN92913.1 - 5.3e-37 127.4 0.0 9.6e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EDN92913.1 - 1.6e-24 85.4 16.9 7.7e-24 83.3 7.5 2.8 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal Mso1_Sec1_bdg PF14475.1 EDN92916.1 - 8.7e-14 50.6 0.0 1.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EDN92917.1 - 7.3e-33 113.4 0.6 7.3e-33 113.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EDN92917.1 - 2.5e-21 75.6 21.8 2.5e-21 75.6 15.1 3.6 2 2 0 2 2 2 1 Mak16 protein C-terminal region CENP-T PF15511.1 EDN92917.1 - 0.058 12.6 12.5 0.073 12.3 8.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 EDN92917.1 - 0.21 9.8 22.8 0.26 9.6 15.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EDN92917.1 - 0.63 7.8 25.7 0.87 7.4 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF952 PF06108.7 EDN92918.1 - 6.5e-26 90.0 0.0 8.1e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Anillin PF08174.6 EDN92919.1 - 3e-31 108.3 0.5 7.2e-31 107.1 0.4 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EDN92919.1 - 7.6e-08 32.5 0.0 2.5e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF2150 PF09920.4 EDN92921.1 - 0.013 15.0 0.4 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) RAI16-like PF10257.4 EDN92922.1 - 1.4e-86 290.6 0.4 2.1e-86 290.0 0.3 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF3140 PF11338.3 EDN92926.1 - 0.095 12.8 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) ketoacyl-synt PF00109.21 EDN92927.1 - 4.2e-60 203.3 1.6 9e-60 202.2 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDN92927.1 - 2.3e-30 104.8 1.3 2.3e-30 104.8 0.9 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EDN92927.1 - 6.7e-06 25.2 0.0 2.8e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Acetyltransf_6 PF13480.1 EDN92928.1 - 0.036 14.0 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_2 PF13347.1 EDN92929.1 - 1e-05 24.1 14.3 1e-05 24.1 9.9 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 EDN92929.1 - 0.00087 18.0 39.9 0.078 11.6 27.7 3.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Mito_carr PF00153.22 EDN92930.1 - 2.4e-70 232.3 0.9 4.7e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EDN92931.1 - 7.3e-26 90.5 0.0 1.7e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Med22 PF06179.7 EDN92932.1 - 3e-20 72.2 0.4 4.3e-20 71.7 0.3 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DEAD PF00270.24 EDN92933.1 - 1.9e-45 154.4 0.1 1.6e-42 144.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN92933.1 - 1e-19 70.1 0.0 2.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN92933.1 - 4.3e-05 23.4 0.1 9.1e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN92933.1 - 0.0076 16.3 0.1 0.081 13.0 0.1 2.5 2 2 0 2 2 2 1 AAA domain SecA_DEAD PF07517.9 EDN92933.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_30 PF13604.1 EDN92933.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDN92933.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) adh_short PF00106.20 EDN92934.1 - 3.1e-29 102.0 0.7 3.9e-29 101.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN92934.1 - 7.3e-27 94.6 0.2 8.3e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN92934.1 - 2e-15 56.9 0.3 2.6e-15 56.5 0.2 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EDN92934.1 - 0.055 13.0 0.2 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Death PF00531.17 EDN92934.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Death domain NicO PF03824.11 EDN92935.1 - 4.8e-41 140.9 11.7 6.2e-41 140.5 8.1 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF1295 PF06966.7 EDN92936.1 - 8.2e-06 25.2 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) BTB PF00651.26 EDN92937.1 - 9.4e-10 38.4 0.0 2.3e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DHFR_1 PF00186.14 EDN92938.1 - 2e-30 105.4 0.0 7.6e-30 103.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase Tenui_NS3 PF05310.7 EDN92939.1 - 0.025 14.4 0.2 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus movement protein GET2 PF08690.5 EDN92939.1 - 0.025 13.8 0.6 0.036 13.3 0.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Rhabdo_matrix PF03397.9 EDN92940.1 - 0.027 13.8 0.0 0.033 13.5 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus matrix protein DUF3827 PF12877.2 EDN92940.1 - 0.17 9.9 4.0 0.17 9.9 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CAAD PF14159.1 EDN92941.1 - 0.11 12.0 0.1 0.13 11.9 0.1 1.0 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ubiq_cyt_C_chap PF03981.7 EDN92943.1 - 4.5e-34 117.3 0.1 7e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Cript PF10235.4 EDN92946.1 - 1.9e-15 56.9 0.6 1.9e-15 56.9 0.4 2.4 2 1 1 3 3 3 2 Microtubule-associated protein CRIPT HAD PF12710.2 EDN92948.1 - 1.4e-21 77.5 0.2 3.7e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN92948.1 - 7.9e-21 74.1 0.2 1.7e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN92948.1 - 3.4e-15 57.0 1.7 6.5e-14 52.8 1.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN92948.1 - 5.4e-11 42.2 0.0 1.6e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN92948.1 - 0.00039 20.0 0.1 0.0076 15.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDN92948.1 - 0.015 15.5 0.2 0.044 14.0 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Cupin_1 PF00190.17 EDN92949.1 - 1.8e-26 92.3 0.0 3.5e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EDN92949.1 - 1e-23 82.5 0.8 5.4e-12 45.0 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EDN92949.1 - 3.1e-10 39.2 0.2 0.00057 19.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EDN92949.1 - 8.1e-08 32.0 0.0 1.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EDN92949.1 - 1.6e-06 27.8 0.1 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain FdtA PF05523.6 EDN92949.1 - 5.4e-06 25.9 0.0 0.099 12.1 0.0 2.2 2 0 0 2 2 2 2 WxcM-like, C-terminal Cupin_6 PF12852.2 EDN92949.1 - 0.00031 20.4 0.1 0.04 13.5 0.0 2.6 3 0 0 3 3 3 1 Cupin 3-HAO PF06052.7 EDN92949.1 - 0.0014 18.0 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.1 EDN92949.1 - 0.036 13.5 0.0 1 8.8 0.0 2.6 3 0 0 3 3 3 0 Cupin-like domain Cupin_4 PF08007.7 EDN92949.1 - 0.17 11.0 0.0 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Zn_clus PF00172.13 EDN92950.1 - 6.6e-07 29.1 11.6 1.2e-06 28.2 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4315 PF14193.1 EDN92950.1 - 0.03 14.2 1.0 0.03 14.2 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF2800 PF10926.3 EDN92950.1 - 0.088 11.9 1.0 0.2 10.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Peptidase_S64 PF08192.6 EDN92950.1 - 1.2 7.4 4.9 0.56 8.4 1.8 1.6 2 0 0 2 2 2 0 Peptidase family S64 He_PIG PF05345.7 EDN92953.1 - 0.2 11.7 1.6 1.3 9.1 0.4 2.6 1 1 1 2 2 2 0 Putative Ig domain Fungal_trans PF04082.13 EDN92954.1 - 7.1e-19 67.6 0.5 1.2e-18 66.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN92954.1 - 2.1e-05 24.2 3.2 4e-05 23.4 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spo12 PF05032.7 EDN92955.1 - 1.5e-09 37.2 0.6 4.4e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 Spo12 family Nucleoporin_FG PF13634.1 EDN92955.1 - 0.22 11.7 5.3 0.29 11.3 3.7 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Acyl-CoA_dh_1 PF00441.19 EDN92956.1 - 3.5e-27 95.3 0.2 1.3e-26 93.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN92956.1 - 1.8e-17 62.5 0.0 4.2e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EDN92956.1 - 6.2e-16 58.8 0.0 4.4e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN92956.1 - 3.6e-14 53.3 0.1 9.1e-14 51.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain MMR_HSR1 PF01926.18 EDN92957.1 - 1.8e-17 63.3 0.1 2.7e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN92957.1 - 6.3e-07 28.8 0.2 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN92957.1 - 8.5e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN92957.1 - 0.00012 21.9 0.2 0.026 14.3 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EDN92957.1 - 0.0051 15.9 0.1 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EDN92957.1 - 0.022 15.2 0.0 0.072 13.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PPP4R2 PF09184.6 EDN92957.1 - 2 7.8 13.8 4.1 6.8 9.6 1.4 1 0 0 1 1 1 0 PPP4R2 CENP-B_dimeris PF09026.5 EDN92957.1 - 3 8.1 11.4 9.6 6.5 7.9 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LTV PF04180.9 EDN92958.1 - 3.5e-104 349.6 20.4 4e-104 349.4 14.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.11 EDN92959.1 - 7.1e-48 162.8 0.3 1.2e-47 162.1 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDN92959.1 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DKCLD PF08068.7 EDN92960.1 - 6.2e-29 99.7 0.1 4.1e-28 97.0 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EDN92960.1 - 6.6e-23 81.5 4.6 3.1e-21 76.0 0.1 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EDN92960.1 - 6.7e-22 77.0 1.3 1.6e-21 75.8 0.9 1.7 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 EDN92960.1 - 0.62 9.7 11.1 1.2 8.7 7.7 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TGS PF02824.16 EDN92961.1 - 2.7e-19 68.7 0.1 4.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDN92961.1 - 6e-19 68.1 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN92961.1 - 1.1e-12 47.5 0.0 1.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDN92961.1 - 1.1e-05 25.2 0.5 0.023 14.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EDN92961.1 - 0.0018 18.7 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EDN92961.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EDN92961.1 - 0.057 12.1 0.3 0.14 10.9 0.1 1.7 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EDN92961.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 EDN92961.1 - 0.19 12.5 1.4 0.91 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Malic_M PF03949.10 EDN92962.1 - 7.2e-91 304.2 0.0 9.9e-91 303.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDN92962.1 - 1.2e-48 165.1 0.0 1.9e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3551 PF12071.3 EDN92962.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) RAI1 PF08652.6 EDN92963.1 - 1.8e-22 78.8 0.1 4.2e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Pox_Ag35 PF03286.9 EDN92964.1 - 0.1 12.0 0.1 0.1 12.0 0.0 1.8 2 1 0 2 2 2 0 Pox virus Ag35 surface protein DUF410 PF04190.8 EDN92965.1 - 5.1e-47 160.5 0.0 6.2e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) vWA-TerF-like PF10138.4 EDN92966.1 - 1.5e-09 38.0 0.4 2.4e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EDN92966.1 - 0.003 17.6 1.9 0.083 12.9 1.3 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain MurB_C PF02873.11 EDN92966.1 - 0.0093 15.7 0.0 0.054 13.2 0.0 2.0 1 1 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain VWA PF00092.23 EDN92966.1 - 0.039 13.6 0.2 0.039 13.6 0.1 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Voltage_CLC PF00654.15 EDN92967.1 - 2.1e-70 237.5 35.7 1.5e-38 132.7 12.7 2.4 2 1 1 3 3 3 2 Voltage gated chloride channel CBS PF00571.23 EDN92967.1 - 4e-07 29.7 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Neurochondrin PF05536.6 EDN92968.1 - 3.8e-74 249.9 0.6 2.8e-48 164.5 0.0 2.3 1 1 1 2 2 2 2 Neurochondrin RIX1 PF08167.7 EDN92968.1 - 0.0057 16.3 2.4 0.0088 15.7 0.4 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec7_N PF12783.2 EDN92968.1 - 0.054 12.9 2.0 0.1 12.0 0.1 2.4 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF720 PF05302.6 EDN92969.1 - 0.048 13.4 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF2985 PF11204.3 EDN92970.1 - 1.1e-29 101.9 2.4 2.6e-29 100.7 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Ycf1 PF05758.7 EDN92970.1 - 0.037 11.7 0.3 0.05 11.3 0.2 1.1 1 0 0 1 1 1 0 Ycf1 Cellulase PF00150.13 EDN92972.1 - 7.9e-46 156.5 0.1 1.1e-45 156.0 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_22 PF13401.1 EDN92973.1 - 1.1e-08 35.2 1.3 7.5e-08 32.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain TPR_12 PF13424.1 EDN92973.1 - 8.3e-05 22.4 15.4 2 8.4 0.0 7.0 6 2 1 7 7 7 3 Tetratricopeptide repeat AAA_16 PF13191.1 EDN92973.1 - 0.00094 19.2 0.9 0.0077 16.2 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 EDN92973.1 - 0.0054 16.6 0.1 0.034 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN92973.1 - 0.031 14.0 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EDN92973.1 - 0.034 14.9 0.0 0.18 12.6 0.0 2.4 1 0 0 1 1 1 0 AAA domain O-FucT PF10250.4 EDN92975.1 - 2.5e-07 30.1 0.0 2.5e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HA2 PF04408.18 EDN92976.1 - 2.9e-20 72.1 0.0 1.3e-19 70.0 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN92976.1 - 5.8e-13 48.5 0.0 2.2e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDN92976.1 - 1.6e-12 47.2 0.0 4.6e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EDN92976.1 - 1.5e-08 34.2 0.1 4.9e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN92976.1 - 3.8e-05 23.8 0.1 0.00027 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDN92976.1 - 0.011 14.6 0.0 0.025 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EDN92976.1 - 0.013 15.2 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EDN92976.1 - 0.017 14.9 2.2 2.2 8.0 0.0 3.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EDN92976.1 - 0.031 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EDN92976.1 - 0.078 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Med6 PF04934.9 EDN92977.1 - 2.8e-40 137.1 0.0 4e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Transp_cyt_pur PF02133.10 EDN92978.1 - 3.4e-95 319.1 40.8 4e-95 318.9 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EDN92979.1 - 1.6e-27 96.3 0.1 4.2e-27 94.9 0.0 1.7 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN92979.1 - 1.2e-19 70.4 0.0 2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CoaE PF01121.15 EDN92983.1 - 3.3e-43 147.1 0.0 5.4e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EDN92983.1 - 0.001 19.8 0.0 0.0045 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EDN92983.1 - 0.023 14.5 0.0 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.1 EDN92983.1 - 0.036 14.3 1.5 0.25 11.6 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EDN92983.1 - 0.1 12.4 0.0 0.87 9.4 0.0 2.5 1 1 0 1 1 1 0 AAA domain Toxin_38 PF14866.1 EDN92985.1 - 0.076 13.1 0.4 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Potassium channel toxin ILVD_EDD PF00920.16 EDN92987.1 - 8e-204 677.8 0.2 9.3e-204 677.6 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EDN92987.1 - 0.028 14.3 0.1 0.21 11.5 0.0 2.4 3 0 0 3 3 3 0 5'-nucleotidase, C-terminal domain Peptidase_S28 PF05577.7 EDN92990.1 - 2.6e-42 144.9 0.9 2e-35 122.2 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_M35 PF02102.10 EDN92993.1 - 2.3e-28 98.9 16.2 3e-28 98.5 11.3 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EDN92993.1 - 1.8e-07 31.7 1.5 6.2e-07 30.0 1.0 1.9 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EDN92993.1 - 0.0049 16.3 0.5 0.0049 16.3 0.4 1.6 2 0 0 2 2 2 1 Putative peptidase family DUF4352 PF11611.3 EDN92993.1 - 0.043 13.9 1.6 0.071 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) Hormone_recep PF00104.25 EDN92994.1 - 0.067 12.3 0.1 0.071 12.2 0.1 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Apc3 PF12895.2 EDN93001.1 - 0.071 13.2 0.5 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BH3 PF15285.1 EDN93003.1 - 0.071 12.6 0.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting Lipase_3 PF01764.20 EDN93004.1 - 1.9e-19 69.7 0.0 3.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Kv2channel PF03521.9 EDN93004.1 - 0.019 14.4 0.2 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel DUF2974 PF11187.3 EDN93004.1 - 0.046 13.0 0.1 1.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) adh_short_C2 PF13561.1 EDN93005.1 - 9.7e-27 94.2 0.4 1.2e-26 94.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN93005.1 - 2.1e-23 83.0 2.2 3.4e-23 82.3 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN93005.1 - 3.1e-07 30.2 0.1 3.1e-07 30.2 0.1 1.5 2 0 0 2 2 2 1 KR domain Kp4 PF09044.5 EDN93005.1 - 0.08 12.7 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Kp4 Peptidase_C2 PF00648.16 EDN93006.1 - 6.7e-52 176.3 0.2 9.5e-35 120.0 0.1 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease MIP-T3 PF10243.4 EDN93006.1 - 1.8 6.9 95.4 0.61 8.4 40.4 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 ILVD_EDD PF00920.16 EDN93007.1 - 2.7e-191 636.5 5.3 3.3e-191 636.2 3.7 1.0 1 0 0 1 1 1 1 Dehydratase family DUF498 PF04430.9 EDN93008.1 - 7.2e-26 89.9 0.0 9.9e-26 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) NADH_B2 PF14813.1 EDN93010.1 - 0.027 14.1 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Peptidase_M16_C PF05193.16 EDN93011.1 - 1.9e-32 112.4 0.0 8.8e-21 74.4 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDN93011.1 - 1.6e-22 79.8 1.9 1.5e-21 76.6 0.3 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Acyltransferase PF01553.16 EDN93015.1 - 1.4e-34 118.3 0.0 2.7e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EDN93015.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP SNO PF01174.14 EDN93016.1 - 6.3e-50 169.4 0.0 1.2e-38 132.6 0.0 2.7 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDN93016.1 - 2.2e-08 33.8 0.0 5.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EDN93016.1 - 0.00072 19.0 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EDN93016.1 - 0.0059 16.0 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EDN93016.1 - 0.043 13.1 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Peptidase_S51 PF03575.12 EDN93016.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Rad60-SLD PF11976.3 EDN93018.1 - 8.4e-19 67.0 1.2 9.9e-19 66.8 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Imm-NTF2 PF15655.1 EDN93018.1 - 0.012 16.0 0.1 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 NTF2 fold immunity protein B3 PF02362.16 EDN93018.1 - 0.026 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 B3 DNA binding domain ubiquitin PF00240.18 EDN93018.1 - 0.051 12.9 0.6 0.064 12.6 0.4 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF1793 PF08760.6 EDN93024.1 - 3.1e-65 219.2 0.8 5.8e-65 218.3 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF3638 PF12340.3 EDN93025.1 - 1.7e-92 308.5 0.7 3.2e-92 307.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EDN93025.1 - 8.4e-16 56.8 0.2 1.6e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MAPEG PF01124.13 EDN93028.1 - 9.6e-13 47.8 0.2 1.2e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 MAPEG family Abhydrolase_6 PF12697.2 EDN93029.1 - 1.8e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93029.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNase_H PF00075.19 EDN93033.1 - 4e-15 56.3 0.0 6.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN93033.1 - 0.0027 18.0 0.2 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EDN93034.1 - 0.022 14.3 1.4 0.034 13.7 0.1 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase WD40 PF00400.27 EDN93035.1 - 1.7e-106 344.6 22.9 5.6e-15 54.5 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 EDN93035.1 - 3.7e-12 46.2 1.3 9.3e-06 25.3 0.1 2.6 1 1 1 2 2 2 2 NACHT domain PD40 PF07676.7 EDN93035.1 - 1.1e-06 28.1 9.6 33 4.3 0.0 7.5 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EDN93035.1 - 4.9e-05 21.8 0.2 1.3 7.2 0.0 3.6 1 1 3 4 4 4 4 Cytochrome D1 heme domain AAA_19 PF13245.1 EDN93035.1 - 0.031 14.0 0.0 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 EDN93035.1 - 0.29 10.2 0.0 0.49 9.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3435 PF11917.3 EDN93036.1 - 4.7e-28 98.0 2.4 5e-28 97.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF2515 PF10720.4 EDN93036.1 - 0.0055 15.6 0.2 0.026 13.4 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2515) DUF2851 PF11013.3 EDN93036.1 - 0.032 12.9 0.5 0.039 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) CM_2 PF01817.16 EDN93036.1 - 0.26 11.4 5.5 0.11 12.6 1.9 1.8 2 1 0 2 2 2 0 Chorismate mutase type II DUF3373 PF11853.3 EDN93036.1 - 0.38 9.2 3.3 5.3 5.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Aa_trans PF01490.13 EDN93040.1 - 2.3e-28 98.8 28.9 7.9e-12 44.3 1.7 3.0 1 1 2 3 3 3 3 Transmembrane amino acid transporter protein Lysozyme_like PF13702.1 EDN93042.1 - 0.014 14.8 0.2 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Lysozyme-like FANCI_S1-cap PF14674.1 EDN93043.1 - 0.033 14.2 0.1 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 cap Poxvirus_B22R_C PF13168.1 EDN93043.1 - 0.067 12.4 0.1 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Abhydrolase_6 PF12697.2 EDN93045.1 - 6.2e-09 36.0 0.0 7.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93045.1 - 4.5e-06 26.4 0.0 4.8e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN93046.1 - 3.5e-25 89.2 0.0 4.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN93046.1 - 1.3e-11 44.5 0.0 9.8e-11 41.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN93046.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN93046.1 - 7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase 2OG-FeII_Oxy_3 PF13640.1 EDN93047.1 - 5.7e-08 33.1 0.0 9.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDN93047.1 - 1e-05 25.7 0.0 2.9e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1489 PF07370.6 EDN93047.1 - 0.064 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) DUF1675 PF07897.6 EDN93048.1 - 0.14 12.0 11.1 0.19 11.5 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PseudoU_synth_1 PF01416.15 EDN93049.1 - 2.7e-22 79.1 0.2 2.6e-10 40.6 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase TFIIE_alpha PF02002.12 EDN93050.1 - 1.6e-15 56.4 0.2 3.1e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-TFIIB PF13453.1 EDN93050.1 - 0.056 12.6 0.5 0.1 11.8 0.3 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-FPG_IleRS PF06827.9 EDN93050.1 - 0.19 11.4 1.4 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS BNIP3 PF06553.7 EDN93050.1 - 1.1 8.5 3.8 1.9 7.8 2.6 1.4 1 0 0 1 1 1 0 BNIP3 PALP PF00291.20 EDN93051.1 - 4.8e-61 206.6 0.1 5.8e-61 206.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EDN93051.1 - 5.7e-09 35.6 0.0 1.7e-07 30.8 0.0 2.6 2 0 0 2 2 2 1 CBS domain GPI-anchored PF10342.4 EDN93052.1 - 2.7e-17 63.0 1.9 2.7e-17 63.0 1.3 3.0 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EDN93052.1 - 9.3e-14 51.6 7.8 9.3e-14 51.6 5.4 2.5 1 1 1 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 DUF824 PF05688.6 EDN93052.1 - 0.95 9.1 6.4 0.12 12.0 0.7 2.3 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) Cyclin PF08613.6 EDN93054.1 - 5.5e-38 130.7 0.0 7.7e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDN93054.1 - 0.024 14.2 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain CLU_N PF15044.1 EDN93054.1 - 0.093 12.8 0.1 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Peptidase_M24 PF00557.19 EDN93055.1 - 8.4e-54 182.2 0.0 1.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDN93055.1 - 4.7e-27 93.9 0.0 1.9e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain TPP_enzyme_N PF02776.13 EDN93056.1 - 1.1e-35 122.6 0.1 3.6e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN93056.1 - 1.1e-20 73.7 0.0 6.3e-20 71.3 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN93056.1 - 3.4e-20 72.1 0.1 9.3e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DDE_Tnp_IS1595 PF12762.2 EDN93058.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 ISXO2-like transposase domain LrgB PF04172.11 EDN93059.1 - 7.4e-29 100.4 7.3 1.7e-28 99.2 5.1 1.6 1 0 0 1 1 1 1 LrgB-like family DUF4526 PF15029.1 EDN93059.1 - 0.13 11.8 2.8 0.16 11.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) DUF1614 PF07758.6 EDN93059.1 - 0.3 10.8 11.1 0.04 13.6 3.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) MAPEG PF01124.13 EDN93060.1 - 5.6e-21 74.4 0.5 7e-21 74.1 0.4 1.1 1 0 0 1 1 1 1 MAPEG family EHN PF06441.7 EDN93061.1 - 2.3e-31 108.0 3.2 3.6e-31 107.3 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EDN93061.1 - 5.5e-11 42.7 0.5 3.8e-10 40.0 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN93061.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.19 EDN93062.1 - 1.9e-66 224.5 0.0 2.6e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EDN93064.1 - 1.1e-40 139.3 0.0 1.9e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EDN93064.1 - 7.5e-06 26.1 0.1 1.7e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDN93064.1 - 3.3e-05 24.0 0.1 8.7e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 PH domain Choline_kinase PF01633.15 EDN93065.1 - 8.2e-08 32.0 0.0 1.6e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EDN93065.1 - 1.8e-07 31.1 0.1 2.7e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SRP72 PF08492.7 EDN93066.1 - 9.4e-13 48.3 4.2 3e-12 46.7 2.9 1.9 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_2 PF07719.12 EDN93066.1 - 1.6e-07 30.6 18.9 0.022 14.6 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDN93066.1 - 3.4e-07 30.5 13.3 0.17 12.2 0.2 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EDN93066.1 - 1.1e-05 25.4 7.1 1 9.5 2.9 4.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDN93066.1 - 3.5e-05 24.0 12.7 0.98 10.2 0.1 6.6 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN93066.1 - 0.00016 22.2 20.6 0.44 11.2 0.1 5.3 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN93066.1 - 0.00025 20.8 4.9 0.27 11.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.5 EDN93066.1 - 0.0007 18.7 0.2 0.059 12.4 0.0 2.6 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EDN93066.1 - 0.0024 17.7 12.9 0.22 11.5 0.0 4.7 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN93066.1 - 0.025 14.2 11.7 0.77 9.4 1.2 4.5 4 1 1 5 5 5 0 TPR repeat TPR_1 PF00515.23 EDN93066.1 - 0.042 13.4 9.8 0.15 11.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDN93066.1 - 0.17 12.1 1.9 6.6 7.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN93066.1 - 0.43 10.5 5.6 49 4.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAUB PF08164.7 EDN93068.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.7 1 1 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Ank_2 PF12796.2 EDN93069.1 - 2e-32 111.3 0.5 9.9e-19 67.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN93069.1 - 9.4e-32 107.2 6.0 3.9e-09 35.8 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EDN93069.1 - 1e-22 80.0 4.0 4.1e-06 27.1 0.3 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN93069.1 - 1.4e-22 77.5 2.8 1.4e-07 31.0 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EDN93069.1 - 1.2e-21 76.1 9.1 5.3e-10 39.2 0.3 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) zf-DHHC PF01529.15 EDN93069.1 - 0.00025 20.5 8.7 0.0083 15.5 0.2 3.1 3 0 0 3 3 3 2 DHHC palmitoyltransferase SRPRB PF09439.5 EDN93070.1 - 1.3e-31 109.1 0.0 4.3e-31 107.5 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DNA_pol_lambd_f PF10391.4 EDN93070.1 - 2.4e-21 75.0 0.8 5.8e-21 73.7 0.6 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EDN93070.1 - 6e-20 70.7 0.1 1.3e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EDN93070.1 - 4.3e-19 68.6 0.0 9.8e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EDN93070.1 - 5e-09 36.2 0.0 2.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain MMR_HSR1 PF01926.18 EDN93070.1 - 4.5e-06 26.6 0.2 1.8e-05 24.6 0.0 2.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EDN93070.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EDN93070.1 - 0.0017 17.6 0.0 0.016 14.4 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EDN93070.1 - 0.0023 18.0 0.0 0.0072 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EDN93070.1 - 0.0024 16.9 0.0 0.0059 15.6 0.0 1.6 1 0 0 1 1 1 1 Septin NTP_transf_2 PF01909.18 EDN93070.1 - 0.0085 16.4 0.0 0.032 14.5 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain ABC_tran PF00005.22 EDN93070.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EDN93070.1 - 0.017 14.6 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EDN93070.1 - 0.02 14.3 0.2 0.17 11.3 0.2 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN93070.1 - 0.024 13.8 0.1 0.13 11.4 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EDN93070.1 - 0.031 14.7 0.0 0.097 13.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EDN93070.1 - 0.071 12.6 0.1 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EDN93070.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EDN93070.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EDN93070.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Rotamase PF00639.16 EDN93071.1 - 4.9e-21 75.2 0.1 8.8e-21 74.4 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EDN93071.1 - 5e-16 59.0 0.0 6.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EDN93071.1 - 2.7e-06 27.0 0.3 6e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EDN93071.1 - 1.6e-05 25.4 0.0 3.1e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain MbtH PF03621.8 EDN93071.1 - 0.12 11.7 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 MbtH-like protein RNA_POL_M_15KD PF02150.11 EDN93072.1 - 5.7e-13 48.3 1.9 1.1e-12 47.3 1.3 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EDN93072.1 - 0.0051 16.7 3.8 0.089 12.7 0.2 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EDN93072.1 - 0.036 13.8 2.9 0.036 13.8 2.0 2.0 2 0 0 2 2 2 0 Double zinc ribbon zf-C2HC5 PF06221.8 EDN93072.1 - 1.7 8.4 6.9 4.3 7.1 0.2 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE PF01363.16 EDN93072.1 - 2.2 8.2 6.5 2.5 8.0 1.0 2.4 2 1 0 2 2 2 0 FYVE zinc finger zf-C3HC4_3 PF13920.1 EDN93072.1 - 7.2 6.3 9.8 1.2 8.8 0.1 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L14 PF00238.14 EDN93073.1 - 1.9e-36 124.4 2.7 2.2e-36 124.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EDN93074.1 - 8.2e-09 35.9 9.6 1.2e-08 35.3 0.3 4.2 3 2 0 3 3 3 1 SET domain BTB PF00651.26 EDN93075.1 - 0.00059 19.8 0.0 0.0031 17.4 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.1 EDN93076.1 - 4e-20 72.1 14.7 6.4e-16 58.4 2.1 2.6 3 0 0 3 3 3 2 PAP2 superfamily PAP2_C PF14360.1 EDN93076.1 - 0.026 14.8 1.2 0.026 14.8 0.8 3.7 5 0 0 5 5 5 0 PAP2 superfamily C-terminal RtcB PF01139.12 EDN93076.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB YL1 PF05764.8 EDN93079.1 - 0.00028 20.5 4.9 0.00028 20.5 3.4 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Nop53 PF07767.6 EDN93079.1 - 0.079 11.9 15.5 0.011 14.7 6.9 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) eIF-3c_N PF05470.7 EDN93079.1 - 0.13 10.2 8.2 0.23 9.5 5.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus zf-CCHC PF00098.18 EDN93079.1 - 0.18 11.7 5.4 0.88 9.6 3.8 2.0 1 1 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EDN93079.1 - 0.35 10.7 0.2 0.35 10.7 0.1 3.2 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Spt5_N PF11942.3 EDN93079.1 - 0.38 11.4 10.9 0.059 13.9 4.4 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EDN93079.1 - 0.85 7.5 6.9 1.3 6.9 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein MPP6 PF10175.4 EDN93079.1 - 2.1 8.7 0.0 2.1 8.7 0.0 3.5 4 0 0 4 4 4 0 M-phase phosphoprotein 6 DUF4139 PF13598.1 EDN93079.1 - 4.4 6.5 9.1 0.25 10.6 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) Merozoite_SPAM PF07133.6 EDN93079.1 - 4.5 7.1 15.1 1.2 9.0 7.0 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) zf-CHCC PF10276.4 EDN93080.1 - 2.3e-15 56.1 2.1 3.8e-15 55.4 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EDN93080.1 - 0.089 12.4 0.9 0.18 11.4 0.1 1.9 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Vb NUDIX_2 PF13869.1 EDN93081.1 - 1.6e-82 275.4 0.0 1.9e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 EDN93082.1 - 1.6e-41 140.8 0.0 1.8e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF2339 PF10101.4 EDN93083.1 - 0.013 13.8 6.3 0.017 13.4 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) YfhO PF09586.5 EDN93083.1 - 0.057 11.4 2.8 0.08 10.9 1.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 7TMR-DISM_7TM PF07695.6 EDN93083.1 - 0.074 12.7 12.3 0.14 11.8 8.5 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.1 EDN93083.1 - 3 7.2 8.5 47 3.3 5.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1675 PF07897.6 EDN93084.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PDE6_gamma PF04868.7 EDN93085.1 - 0.0028 17.4 2.7 0.91 9.4 0.4 3.0 1 1 2 3 3 3 3 Retinal cGMP phosphodiesterase, gamma subunit 5_3_exonuc_N PF02739.11 EDN93085.1 - 0.31 10.4 12.4 1.5 8.1 0.2 3.9 1 1 3 4 4 4 0 5'-3' exonuclease, N-terminal resolvase-like domain APH PF01636.18 EDN93086.1 - 7.9e-14 51.9 0.0 2.4e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN93086.1 - 1.3e-09 37.9 0.0 9.6e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EDN93086.1 - 0.0015 17.7 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain ADH_zinc_N PF00107.21 EDN93087.1 - 2.9e-24 85.0 0.0 4.3e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN93087.1 - 3.4e-12 47.3 0.0 6.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN93087.1 - 0.0009 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain D123 PF07065.9 EDN93088.1 - 1.6e-97 326.1 0.0 2.9e-97 325.3 0.0 1.4 1 1 0 1 1 1 1 D123 cwf21 PF08312.7 EDN93089.1 - 2.1e-16 59.4 14.0 4.1e-16 58.5 9.7 1.5 1 0 0 1 1 1 1 cwf21 domain DUF2346 PF09803.4 EDN93090.1 - 1.6e-05 24.6 0.1 2.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Transcrip_reg PF01709.15 EDN93091.1 - 9e-40 136.2 0.3 1e-39 136.0 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator Flagellin_IN PF07196.8 EDN93091.1 - 0.087 12.8 0.7 0.19 11.7 0.5 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif HEAT_2 PF13646.1 EDN93092.1 - 3.9e-13 49.4 5.5 6.7e-05 23.0 0.0 6.1 5 1 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EDN93092.1 - 5.1e-07 29.9 0.2 0.053 13.8 0.0 5.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDN93092.1 - 4.6e-06 26.2 17.7 0.074 13.1 0.0 8.9 10 1 1 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 EDN93092.1 - 0.035 14.6 10.3 15 6.2 0.0 7.2 6 3 2 8 8 8 0 HEAT-like repeat CLASP_N PF12348.3 EDN93093.1 - 0.057 12.7 2.5 0.14 11.4 0.1 2.7 3 0 0 3 3 3 0 CLASP N terminal APH PF01636.18 EDN93095.1 - 7.1e-06 25.9 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN93095.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase RVT_1 PF00078.22 EDN93096.1 - 1.6e-13 50.5 0.0 3.1e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDN93097.1 - 9e-23 80.7 0.0 1.9e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN93097.1 - 5.2e-05 22.8 0.1 0.00015 21.3 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EDN93097.1 - 0.076 13.0 2.2 0.39 10.8 0.2 3.1 2 1 0 2 2 2 0 Retrotransposon gag protein Cortex-I_coil PF09304.5 EDN93097.1 - 5.1 7.1 12.4 0.28 11.2 3.2 3.0 3 1 0 3 3 3 0 Cortexillin I, coiled coil WD40 PF00400.27 EDN93098.1 - 6.4e-69 225.5 15.8 5.8e-11 41.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EDN93098.1 - 2.8e-27 94.7 6.2 4.1e-27 94.1 4.3 1.2 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EDN93098.1 - 0.00057 18.2 0.9 0.033 12.4 0.2 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EDN93098.1 - 0.00099 17.3 0.3 0.061 11.4 0.0 3.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDN93098.1 - 0.021 13.5 0.1 0.27 9.9 0.1 2.5 1 1 1 2 2 2 0 Nup133 N terminal like DUF3037 PF11236.3 EDN93098.1 - 0.2 11.7 0.1 0.44 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) FA_hydroxylase PF04116.8 EDN93099.1 - 3.2e-12 46.8 21.3 5.5e-12 46.1 11.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF3435 PF11917.3 EDN93100.1 - 7.5e-18 64.4 0.0 8.8e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.3 EDN93101.1 - 0.0087 14.8 6.5 0.0093 14.7 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) PMAIP1 PF15150.1 EDN93101.1 - 0.017 14.9 0.8 0.029 14.1 0.5 1.4 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced MscS_porin PF12795.2 EDN93101.1 - 0.02 14.2 3.2 0.024 13.9 2.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain THOC7 PF05615.8 EDN93101.1 - 0.078 13.2 6.6 0.11 12.8 4.6 1.3 1 1 0 1 1 1 0 Tho complex subunit 7 APG6 PF04111.7 EDN93101.1 - 0.078 12.0 2.4 0.087 11.8 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 EDN93101.1 - 0.11 12.3 2.0 0.14 12.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Kinetocho_Slk19 PF12709.2 EDN93101.1 - 0.13 12.3 3.3 0.16 12.0 1.3 1.7 2 0 0 2 2 2 0 Central kinetochore-associated Phage_GP20 PF06810.6 EDN93101.1 - 0.14 11.6 1.0 0.23 10.8 0.7 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 vATP-synt_E PF01991.13 EDN93101.1 - 0.15 11.3 2.6 0.17 11.1 1.8 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit HALZ PF02183.13 EDN93101.1 - 0.2 11.3 0.2 0.2 11.3 0.1 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 EDN93101.1 - 0.27 10.7 5.2 3 7.3 0.7 2.7 2 1 1 3 3 3 0 Septum formation initiator Fungal_trans_2 PF11951.3 EDN93101.1 - 0.3 9.6 1.6 0.29 9.6 1.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Baculo_RING PF05883.6 EDN93101.1 - 0.33 10.7 1.8 0.43 10.4 1.3 1.1 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Occludin_ELL PF07303.8 EDN93101.1 - 0.45 11.2 5.1 0.58 10.9 3.6 1.3 1 0 0 1 1 1 0 Occludin homology domain IncA PF04156.9 EDN93101.1 - 0.88 9.1 4.1 1.1 8.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein DUF3007 PF11460.3 EDN93101.1 - 0.99 9.5 4.2 3.8 7.6 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) DUF4225 PF13988.1 EDN93101.1 - 0.99 8.8 3.6 3.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Wbp11 PF09429.5 EDN93101.1 - 1.1 9.3 6.5 2 8.4 4.5 1.6 1 1 0 1 1 1 0 WW domain binding protein 11 DUF904 PF06005.7 EDN93101.1 - 3.7 7.9 6.1 26 5.1 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DDE_1 PF03184.14 EDN93103.1 - 1.6e-36 125.5 0.0 1.8e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HET PF06985.6 EDN93104.1 - 1e-22 80.8 14.6 7.5e-20 71.5 1.9 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.1 EDN93104.1 - 2.1e-21 75.1 4.5 1.1e-08 34.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN93104.1 - 1.1e-20 73.3 5.0 6.4e-17 61.2 1.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EDN93104.1 - 9.7e-11 41.0 0.1 1.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 EDN93104.1 - 4.9e-10 38.5 4.1 0.001 18.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN93104.1 - 9.6e-09 34.4 3.7 0.016 14.9 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat AAA_16 PF13191.1 EDN93104.1 - 3.4e-08 33.6 0.0 9.8e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.1 EDN93104.1 - 6.7e-08 32.0 8.4 4.5e-07 29.4 0.7 2.7 2 1 1 3 3 2 2 TPR repeat TPR_7 PF13176.1 EDN93104.1 - 1.4e-06 27.6 3.2 0.022 14.5 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN93104.1 - 4e-06 26.9 2.3 0.72 10.6 0.2 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN93104.1 - 2.7e-05 23.7 7.1 0.49 10.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN93104.1 - 7.8e-05 22.5 2.5 0.55 10.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 EDN93104.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EDN93104.1 - 0.00043 20.4 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EDN93104.1 - 0.0078 16.1 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF2225 PF09986.4 EDN93104.1 - 0.021 14.2 1.9 0.027 13.9 0.1 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF630 PF04783.7 EDN93104.1 - 0.058 13.3 0.1 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF630) TPR_4 PF07721.9 EDN93104.1 - 0.074 13.5 0.1 20 6.0 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN93104.1 - 0.18 12.4 6.0 7.5 7.3 0.7 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN93104.1 - 0.25 11.8 5.5 28 5.4 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3384 PF11864.3 EDN93105.1 - 0.018 13.5 1.2 0.022 13.2 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) MAS20 PF02064.10 EDN93105.1 - 0.098 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor DUF2246 PF10229.4 EDN93105.1 - 0.1 11.9 0.3 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) DUF4484 PF14831.1 EDN93105.1 - 0.19 11.7 2.0 0.22 11.5 1.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) WD40 PF00400.27 EDN93109.1 - 2.4e-30 103.2 2.8 2.3e-14 52.6 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat HET PF06985.6 EDN93109.1 - 4.5e-21 75.4 8.3 4.2e-19 69.0 5.8 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EDN93109.1 - 7.8e-05 22.3 0.1 0.00019 21.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EDN93109.1 - 0.0016 17.5 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain PD40 PF07676.7 EDN93109.1 - 0.0093 15.6 0.2 6.5 6.5 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ldh_1_C PF02866.13 EDN93110.1 - 5.9e-44 149.8 0.0 8.6e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EDN93110.1 - 2.9e-42 143.8 0.1 3.9e-42 143.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDN93110.1 - 0.047 12.3 0.0 0.073 11.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EDN93110.1 - 0.049 12.7 0.2 0.62 9.1 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EDN93110.1 - 0.14 11.4 0.2 3 7.1 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ribosomal_L28e PF01778.12 EDN93111.1 - 4.4e-42 143.1 0.3 5.6e-42 142.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 EDN93112.1 - 6.2e-50 168.2 0.0 6.9e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TRAPP PF04051.11 EDN93113.1 - 1.4e-25 89.5 0.0 1.7e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Adeno_PVIII PF01310.13 EDN93114.1 - 0.051 13.3 0.4 0.45 10.2 0.3 2.0 1 1 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Rhomboid PF01694.17 EDN93115.1 - 3.1e-16 59.7 12.6 3.1e-16 59.7 8.8 1.8 1 1 1 2 2 2 1 Rhomboid family Sugar_tr PF00083.19 EDN93116.1 - 1.7e-49 168.6 19.1 2e-49 168.4 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 EDN93117.1 - 9.3e-26 90.4 4.0 1.9e-20 72.9 1.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN93117.1 - 7.5e-05 21.6 1.9 7.5e-05 21.6 1.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2837 PF10997.3 EDN93117.1 - 0.00041 19.6 0.5 0.52 9.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2837) Rad1 PF02144.11 EDN93117.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DUF2264 PF10022.4 EDN93118.1 - 1.3e-128 428.6 0.1 1.6e-128 428.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.18 EDN93120.1 - 4.4e-69 233.1 6.8 8.9e-69 232.1 4.7 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EDN93120.1 - 9.7e-56 188.3 1.2 9.7e-56 188.3 0.9 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EDN93120.1 - 1.9e-46 157.8 2.0 2.4e-22 79.2 0.0 3.0 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain DUF4189 PF13827.1 EDN93122.1 - 0.032 14.4 0.4 0.066 13.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4189) API5 PF05918.6 EDN93125.1 - 6.4 5.1 8.0 9 4.6 5.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Hus1 PF04005.7 EDN93126.1 - 4e-95 318.1 0.0 4.5e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein SAP PF02037.22 EDN93127.1 - 1.5e-07 30.7 0.5 2.5e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 SAP domain PA14_2 PF10528.4 EDN93135.1 - 1e-39 134.9 3.4 1.9e-39 134.1 0.9 2.7 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.7 EDN93135.1 - 0.0015 18.2 1.6 0.0036 16.9 0.0 2.5 3 0 0 3 3 3 1 PA14 domain PAN_4 PF14295.1 EDN93135.1 - 0.01 15.5 3.0 0.18 11.5 0.3 2.7 2 0 0 2 2 2 0 PAN domain Amidohydro_2 PF04909.9 EDN93140.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Hydrolase PF00702.21 EDN93142.1 - 1.8e-16 61.2 0.0 7.9e-16 59.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN93142.1 - 3.1e-15 55.8 0.0 7.6e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EDN93142.1 - 4e-10 40.1 0.0 8.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN93142.1 - 0.00053 19.8 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN93142.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.2 EDN93143.1 - 6.6e-103 344.3 0.0 8.8e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EDN93143.1 - 2.7e-31 107.9 0.0 6.2e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.2 EDN93143.1 - 2e-10 41.0 25.4 2e-10 41.0 17.6 5.1 3 2 1 5 5 5 1 Vesicle coat trafficking protein Sec16 N-terminus ORC6 PF05460.8 EDN93149.1 - 0.021 13.9 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TrmE_N PF10396.4 EDN93150.1 - 5.9e-24 84.2 0.0 1.5e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EDN93150.1 - 8.7e-22 77.3 1.8 1.8e-21 76.2 0.4 2.3 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EDN93150.1 - 1.3e-17 63.8 0.0 3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN93150.1 - 3.1e-07 30.3 0.1 7.7e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EDN93150.1 - 7.7e-05 22.0 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDN93150.1 - 0.00017 22.0 0.0 0.00067 20.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EDN93150.1 - 0.0081 15.6 0.0 3.8 6.8 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EDN93150.1 - 0.018 15.3 0.5 0.044 14.0 0.4 1.9 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EDN93150.1 - 0.025 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EDN93150.1 - 0.054 12.5 0.3 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RabGAP-TBC PF00566.13 EDN93151.1 - 9.5e-29 100.4 6.2 9.5e-29 100.4 4.3 1.7 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Response_reg PF00072.19 EDN93151.1 - 4.6e-17 62.0 0.1 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EDN93151.1 - 8.7e-16 57.6 0.0 2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3548 PF12068.3 EDN93151.1 - 5.7e-07 29.0 0.0 4.4e-05 22.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3548) CENP-B_dimeris PF09026.5 EDN93152.1 - 1 9.6 6.6 1.9 8.7 4.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EDN93152.1 - 6.5 7.1 8.6 13 6.1 5.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypan_PARP PF05887.6 EDN93153.1 - 0.00014 21.6 3.7 0.00033 20.4 2.5 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MSA-2c PF12238.3 EDN93153.1 - 0.81 9.3 7.2 0.34 10.5 3.0 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Neisseria_TspB PF05616.8 EDN93153.1 - 4.2 5.6 9.7 6.6 4.9 6.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3684 PF12449.3 EDN93154.1 - 0 1251.2 1.9 0 1111.3 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) MMtag PF10159.4 EDN93154.1 - 6.3e-13 48.5 2.6 6.3e-13 48.5 1.8 2.9 2 0 0 2 2 2 1 Kinase phosphorylation protein HATPase_c_3 PF13589.1 EDN93154.1 - 2.6e-05 23.8 0.0 0.0001 21.9 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_7 PF00840.15 EDN93155.1 - 2.9e-208 691.5 25.1 3.4e-208 691.3 17.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Bac_rhamnosid_N PF08531.5 EDN93155.1 - 0.081 12.4 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_3 PF00933.16 EDN93156.1 - 1.1e-60 205.2 0.1 1.5e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ATG22 PF11700.3 EDN93157.1 - 4.2e-24 84.8 6.0 5.1e-24 84.5 4.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4379 PF14311.1 EDN93158.1 - 0.032 14.0 0.8 0.059 13.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4379) PINIT PF14324.1 EDN93159.1 - 2.3e-38 131.4 0.0 4.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 PINIT domain SAP PF02037.22 EDN93159.1 - 8.1e-05 22.0 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-MIZ PF02891.15 EDN93159.1 - 0.039 13.4 0.4 0.076 12.5 0.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.10 EDN93159.1 - 0.049 13.2 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 EDN93160.1 - 3.1e-18 65.4 1.7 3.1e-18 65.4 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2357 PF09823.4 EDN93160.1 - 0.051 12.6 0.8 0.059 12.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Phosphodiest PF01663.17 EDN93161.1 - 2.4e-14 53.4 2.2 3.2e-13 49.7 1.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PigN PF04987.9 EDN93161.1 - 0.00011 20.9 2.1 0.00011 20.9 1.4 2.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Metalloenzyme PF01676.13 EDN93161.1 - 0.00028 20.3 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EDN93161.1 - 0.08 12.1 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Sulfatase Neur_chan_memb PF02932.11 EDN93162.1 - 0.13 12.1 4.2 0.23 11.3 2.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 EDN93162.1 - 0.2 9.8 0.5 0.25 9.4 0.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Bap31 PF05529.7 EDN93162.1 - 0.26 10.7 7.9 0.22 10.9 2.5 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Cucumo_2B PF03263.8 EDN93162.1 - 2 8.7 5.5 0.51 10.6 0.5 2.3 2 1 0 2 2 2 0 Cucumovirus protein 2B Tom37_C PF11801.3 EDN93162.1 - 2.1 8.1 7.1 9.7 6.0 2.8 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain RR_TM4-6 PF06459.7 EDN93162.1 - 9.9 5.9 13.8 14 5.4 7.9 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Vps51 PF08700.6 EDN93163.1 - 1.5e-13 50.3 0.0 1.1e-12 47.6 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 KxDL PF10241.4 EDN93163.1 - 0.4 10.6 4.1 13 5.8 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein GMC_oxred_N PF00732.14 EDN93164.1 - 2.7e-06 26.7 0.0 3.3e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN93164.1 - 1.5e-05 25.3 0.0 0.00019 21.7 0.0 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN93164.1 - 0.0001 21.2 0.1 0.00019 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDN93164.1 - 0.00065 19.6 0.5 0.0032 17.4 0.3 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDN93164.1 - 0.00085 18.5 0.1 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EDN93164.1 - 0.0026 16.7 0.0 0.0057 15.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDN93164.1 - 0.014 14.2 0.1 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EDN93164.1 - 0.015 15.1 0.1 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN93164.1 - 0.055 11.9 0.0 0.089 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_6 PF12697.2 EDN93164.1 - 0.12 12.2 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EDN93164.1 - 0.12 11.4 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDN93164.1 - 0.14 12.6 0.7 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TRAP_alpha PF03896.11 EDN93167.1 - 6.2e-09 35.2 0.1 1.8e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Rox3 PF08633.5 EDN93168.1 - 5.7e-64 215.9 0.2 5.7e-64 215.9 0.1 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit RRM_1 PF00076.17 EDN93169.1 - 4.2e-59 196.1 0.0 9.8e-18 63.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN93169.1 - 4.1e-42 142.0 0.2 3.4e-12 46.1 0.0 5.5 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN93169.1 - 1.4e-25 88.9 0.4 4.7e-08 32.7 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 EDN93169.1 - 0.00071 18.8 0.0 0.98 8.7 0.0 2.9 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated DUF4253 PF14062.1 EDN93171.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) 2-Hacid_dh_C PF02826.14 EDN93172.1 - 3.2e-51 172.9 0.0 5.6e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN93172.1 - 1.7e-15 56.6 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN93172.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MARVEL PF01284.18 EDN93176.1 - 9.8e-12 44.9 15.2 1.9e-11 43.9 10.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EDN93176.1 - 0.33 10.5 12.3 0.38 10.2 0.0 2.6 2 1 1 3 3 3 0 SUR7/PalI family DUF3357 PF11837.3 EDN93176.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) bZIP_1 PF00170.16 EDN93177.1 - 0.027 14.4 7.1 0.18 11.7 4.9 2.3 1 1 0 1 1 1 0 bZIP transcription factor DUF1866 PF08952.6 EDN93177.1 - 0.067 12.7 0.5 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF2205 PF10224.4 EDN93177.1 - 1.5 8.4 13.0 1.6 8.3 3.5 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF1640 PF07798.6 EDN93179.1 - 8.4e-12 45.4 7.9 8.4e-12 45.4 5.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) BOF PF04076.8 EDN93179.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein NACHT PF05729.7 EDN93180.1 - 1.7e-07 31.0 0.1 1.5e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 NACHT domain Ank PF00023.25 EDN93180.1 - 0.0013 18.4 0.0 3.4 7.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat AAA_22 PF13401.1 EDN93180.1 - 0.0019 18.3 0.0 1.1 9.4 0.0 3.1 2 1 1 3 3 3 2 AAA domain Ank_2 PF12796.2 EDN93180.1 - 0.069 13.4 0.0 0.6 10.4 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Rotamase PF00639.16 EDN93181.1 - 0.012 16.2 2.3 0.012 16.2 0.2 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF2959 PF11172.3 EDN93181.1 - 0.014 15.2 5.9 0.023 14.4 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) DUF4129 PF13559.1 EDN93181.1 - 0.024 14.6 0.1 0.045 13.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Syntaxin PF00804.20 EDN93181.1 - 0.063 13.4 3.9 0.087 12.9 2.3 1.6 1 1 0 1 1 1 0 Syntaxin Syntaxin-6_N PF09177.6 EDN93181.1 - 0.15 12.4 2.9 0.18 12.2 1.1 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Utp11 PF03998.8 EDN93181.1 - 0.19 11.4 6.4 0.24 11.1 4.4 1.1 1 0 0 1 1 1 0 Utp11 protein DUF3216 PF11505.3 EDN93181.1 - 0.2 11.4 4.1 0.36 10.6 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3216) Tom37_C PF11801.3 EDN93181.1 - 0.24 11.2 3.8 0.33 10.8 2.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Ribosomal_L12 PF00542.14 EDN93181.1 - 0.32 11.0 3.1 0.66 10.0 2.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain YtxH PF12732.2 EDN93181.1 - 0.51 10.7 2.7 0.47 10.8 0.6 1.8 2 0 0 2 2 2 0 YtxH-like protein Vpu PF00558.14 EDN93181.1 - 0.76 9.3 4.5 4 7.0 1.3 2.6 1 1 2 3 3 3 0 Vpu protein Rho_Binding PF08912.6 EDN93181.1 - 3.7 7.9 10.0 1.3 9.4 3.1 2.4 1 1 0 2 2 2 0 Rho Binding Aminotran_5 PF00266.14 EDN93183.1 - 7.2e-29 100.6 0.0 8.1e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V GAS2 PF02187.12 EDN93187.1 - 8.8e-05 22.2 0.1 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain RNA_pol_L PF01193.19 EDN93187.1 - 0.0039 16.2 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ketoacyl-synt PF00109.21 EDN93188.1 - 1.6e-06 27.7 0.1 1.6e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain 4HBT_3 PF13622.1 EDN93189.1 - 2.2e-35 122.6 0.7 2.5e-35 122.4 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.17 EDN93191.1 - 1.7e-06 26.8 0.0 2.1e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PNTB PF02233.11 EDN93192.1 - 2.2e-166 554.2 24.2 2.2e-166 554.2 16.8 1.5 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EDN93192.1 - 1.7e-49 167.6 0.3 3.4e-49 166.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EDN93192.1 - 3.3e-46 156.6 0.0 7e-46 155.6 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EDN93192.1 - 8.6e-31 105.9 4.8 8.6e-31 105.9 3.3 4.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EDN93192.1 - 0.0066 15.6 0.0 1.5 7.9 0.0 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EDN93192.1 - 0.0074 15.8 0.3 0.04 13.4 0.2 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EDN93192.1 - 0.035 13.9 1.9 0.11 12.3 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EDN93192.1 - 0.052 13.3 0.5 0.3 10.8 0.1 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain GIDA PF01134.17 EDN93192.1 - 0.087 11.6 1.3 0.16 10.7 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EDN93192.1 - 1.7 8.6 6.0 0.32 11.0 0.3 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Peptidase_S8 PF00082.17 EDN93194.1 - 7.6e-50 169.6 1.7 1.3e-49 168.8 1.2 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EDN93194.1 - 8.4e-12 45.4 0.4 2e-11 44.2 0.3 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) NPCBM_assoc PF10633.4 EDN93194.1 - 0.086 12.8 1.6 0.13 12.2 0.2 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Herpes_UL16 PF03044.9 EDN93195.1 - 0.047 12.6 0.2 0.054 12.4 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family PAP2 PF01569.16 EDN93196.1 - 9.1e-14 51.2 0.4 9.1e-14 51.2 0.3 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EDN93196.1 - 0.0033 17.1 0.1 0.093 12.4 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family RWD PF05773.17 EDN93197.1 - 7.7e-20 70.8 0.0 1.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EDN93197.1 - 2.6e-19 68.8 35.3 2e-13 49.9 1.4 3.9 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EDN93197.1 - 1.7e-05 24.5 6.8 1.7e-05 24.5 4.7 3.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN93197.1 - 0.0011 18.9 8.5 0.0011 18.9 5.9 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN93197.1 - 0.0014 18.2 4.0 0.0014 18.2 2.8 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN93197.1 - 0.0077 15.8 7.1 0.0077 15.8 4.9 4.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDN93197.1 - 0.012 15.3 3.2 0.012 15.3 2.2 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Baculo_RING PF05883.6 EDN93197.1 - 1 9.1 6.8 0.088 12.6 0.6 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain APH PF01636.18 EDN93199.1 - 0.0029 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF687 PF05095.7 EDN93205.1 - 0.016 13.6 0.6 0.022 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) zf-RING_2 PF13639.1 EDN93206.1 - 0.002 17.8 8.3 0.002 17.8 5.8 2.0 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 EDN93206.1 - 0.0089 15.7 8.3 0.0089 15.7 5.7 1.8 2 0 0 2 2 2 1 PHD-finger OrfB_Zn_ribbon PF07282.6 EDN93206.1 - 0.67 9.6 9.2 0.12 12.0 0.4 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Trep_dent_lipo PF09710.5 EDN93207.1 - 0.064 11.9 0.0 0.16 10.5 0.0 1.6 2 0 0 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) PPTA PF01239.17 EDN93207.1 - 0.094 12.1 2.2 3.6 7.1 0.1 2.9 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Methyltransf_31 PF13847.1 EDN93208.1 - 6.8e-27 93.9 0.0 8.7e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN93208.1 - 4e-24 84.9 0.0 6.2e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN93208.1 - 3.4e-17 62.3 0.0 5.1e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EDN93208.1 - 3.5e-15 56.2 0.0 5e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN93208.1 - 7.6e-14 51.7 0.0 1.4e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN93208.1 - 3.7e-13 50.0 0.0 6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN93208.1 - 6.4e-13 48.9 0.0 9.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN93208.1 - 1.1e-09 38.3 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN93208.1 - 5.4e-09 35.6 0.0 8.1e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EDN93208.1 - 2.9e-07 29.7 0.0 4.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 EDN93208.1 - 5.7e-07 29.0 0.0 9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EDN93208.1 - 6.9e-06 25.7 0.0 9.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EDN93208.1 - 0.00067 19.3 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EDN93208.1 - 0.00072 19.1 0.0 0.00098 18.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_9 PF08003.6 EDN93208.1 - 0.0015 17.3 0.0 0.0021 16.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) FmrO PF07091.6 EDN93208.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 EDN93208.1 - 0.0019 17.8 0.2 0.011 15.4 0.2 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.6 EDN93208.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.13 EDN93208.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 EDN93208.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EDN93208.1 - 0.064 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 EDN93208.1 - 0.065 12.1 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 EDN93208.1 - 0.068 12.1 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Mito_carr PF00153.22 EDN93209.1 - 9.3e-25 86.1 0.0 3.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein RRM_1 PF00076.17 EDN93211.1 - 2e-32 110.6 0.0 5.3e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN93211.1 - 2.9e-18 65.6 0.0 1.9e-09 37.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN93211.1 - 4e-14 52.1 0.0 2.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EDN93211.1 - 0.0042 16.5 0.2 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EDN93211.1 - 0.042 13.5 0.3 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 MIF4G_like_2 PF09090.6 EDN93212.1 - 6.1e-24 84.6 0.0 7.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 MIF4G like EF-hand_1 PF00036.27 EDN93212.1 - 0.038 13.2 0.1 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Pkinase PF00069.20 EDN93213.1 - 1.6e-57 194.6 0.0 5.8e-57 192.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93213.1 - 2.5e-21 75.9 0.0 5e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN93213.1 - 6.8e-07 28.5 0.0 1.8e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN93213.1 - 0.004 16.9 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDP-OH_P_transf PF01066.16 EDN93214.1 - 0.0042 17.3 0.2 0.0042 17.3 0.1 1.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RVT_2 PF07727.9 EDN93219.1 - 4.5e-18 65.1 0.1 9.2e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN93219.1 - 2.2e-11 43.9 0.0 5.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN93219.1 - 1.1e-08 34.5 0.0 4.3e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN93219.1 - 1.5e-05 24.7 0.4 3.8e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN93219.1 - 0.00022 20.7 0.6 0.00022 20.7 0.4 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN93219.1 - 0.003 17.0 3.0 0.003 17.0 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle A1_Propeptide PF07966.7 EDN93219.1 - 0.052 13.3 0.0 3.5 7.5 0.0 3.0 2 0 0 2 2 2 0 A1 Propeptide UBN2 PF14223.1 EDN93220.1 - 2.7e-05 23.9 0.1 6.4e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN93220.1 - 0.0049 16.4 0.2 0.022 14.3 0.1 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN93220.1 - 0.032 13.7 0.9 0.032 13.7 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle Consortin_C PF15281.1 EDN93220.1 - 0.057 12.9 1.2 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Consortin C-terminus zf-CCHC PF00098.18 EDN93220.1 - 5.9 7.0 9.1 0.21 11.6 1.8 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.9 EDN93221.1 - 2.9e-73 245.8 0.4 9.6e-73 244.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN93221.1 - 0.00057 19.9 0.0 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDN93221.1 - 0.017 14.4 0.1 0.21 10.9 0.1 2.7 2 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4471 PF14740.1 EDN93221.1 - 0.06 12.5 0.4 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Porin_3 PF01459.17 EDN93222.1 - 1.5e-88 296.6 0.2 1.7e-88 296.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 EDN93223.1 - 2.2e-30 105.3 0.4 1.6e-17 63.3 0.0 2.8 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN93223.1 - 3.7e-21 75.8 0.2 5.9e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UCH_1 PF13423.1 EDN93226.1 - 6.2e-22 78.3 0.3 6.2e-22 78.3 0.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EDN93226.1 - 4.1e-07 29.3 4.3 3.8e-06 26.2 0.4 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 EDN93227.1 - 6e-26 90.0 0.0 9.4e-26 89.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDN93227.1 - 1e-06 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 CYSTM PF12734.2 EDN93229.1 - 1.7e-06 27.9 10.8 1.7e-06 27.9 7.5 2.5 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Dioxygenase_C PF00775.16 EDN93234.1 - 9.6e-14 51.0 0.6 3.5e-13 49.2 0.4 1.9 1 1 0 1 1 1 1 Dioxygenase DUF3402 PF11882.3 EDN93237.1 - 1.2e-113 380.2 1.1 3.5e-95 319.4 0.0 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.8 EDN93237.1 - 1.8e-92 309.3 0.1 2.8e-92 308.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Glyco_hydro_47 PF01532.15 EDN93238.1 - 1.7e-137 458.8 0.0 2e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Podoplanin PF05808.6 EDN93239.1 - 3.8e-06 26.5 1.1 3.8e-06 26.5 0.8 1.7 2 0 0 2 2 2 1 Podoplanin S1FA PF04689.8 EDN93239.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4366 PF14283.1 EDN93239.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Adeno_E3_CR2 PF02439.10 EDN93239.1 - 0.021 14.3 0.4 0.042 13.3 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.8 EDN93239.1 - 0.03 12.9 1.8 0.056 12.0 1.3 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Herpes_gE PF02480.11 EDN93239.1 - 0.035 12.3 0.1 0.049 11.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2668 PF10873.3 EDN93239.1 - 0.041 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Amnionless PF14828.1 EDN93239.1 - 0.05 12.0 0.0 0.07 11.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless IncA PF04156.9 EDN93239.1 - 0.18 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF3042 PF11240.3 EDN93239.1 - 0.2 11.5 0.1 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SKG6 PF08693.5 EDN93239.1 - 0.26 10.6 4.2 0.69 9.2 2.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.7 EDN93239.1 - 0.34 10.3 4.1 0.15 11.5 0.7 1.9 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor Thaumatin PF00314.12 EDN93244.1 - 6e-18 65.1 3.2 8e-18 64.6 2.2 1.2 1 0 0 1 1 1 1 Thaumatin family Ada_Zn_binding PF02805.11 EDN93245.1 - 3e-28 97.1 0.8 4.7e-28 96.5 0.6 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EDN93245.1 - 9.3e-09 34.8 0.0 1.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EDN93245.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN93245.1 - 0.015 14.9 0.2 0.046 13.3 0.0 2.0 2 1 0 2 2 2 0 Homeodomain-like domain DNA_binding_1 PF01035.15 EDN93246.1 - 2.1e-26 91.4 0.0 2.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DHO_dh PF01180.16 EDN93247.1 - 1.4e-24 86.6 0.1 2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DnaJ PF00226.26 EDN93248.1 - 2.4e-18 65.6 0.6 6.3e-18 64.2 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Matrilin_ccoil PF10393.4 EDN93248.1 - 0.032 13.5 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4061 PF13270.1 EDN93248.1 - 0.055 13.5 0.7 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF4407 PF14362.1 EDN93248.1 - 0.26 10.2 1.9 0.28 10.0 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRR PF07709.6 EDN93248.1 - 0.53 10.6 3.0 1.3 9.5 0.0 3.2 5 0 0 5 5 5 0 Seven Residue Repeat DUF2427 PF10348.4 EDN93249.1 - 0.026 14.0 0.7 0.043 13.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) UL2 PF08196.6 EDN93249.1 - 0.11 12.3 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 UL2 protein DASH_Spc34 PF08657.5 EDN93250.1 - 0.0011 18.6 3.7 0.0011 18.6 2.6 1.8 2 0 0 2 2 2 1 DASH complex subunit Spc34 Fungal_trans PF04082.13 EDN93250.1 - 0.0021 17.0 0.1 0.0051 15.7 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN93250.1 - 0.0048 16.7 12.8 0.0098 15.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3Beta_HSD PF01073.14 EDN93251.1 - 8.1e-39 132.9 0.0 7.3e-22 77.3 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN93251.1 - 2.1e-22 79.7 0.0 2.8e-18 66.2 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDN93251.1 - 4.6e-12 46.1 0.0 7.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EDN93251.1 - 7.9e-08 31.5 0.0 4.5e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EDN93251.1 - 9.2e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN93251.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN93251.1 - 2.3e-05 23.4 0.5 0.0014 17.6 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDN93251.1 - 3.2e-05 24.0 0.0 6.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase_Csub PF13950.1 EDN93251.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Glyco_hydro_16 PF00722.16 EDN93252.1 - 1.6e-10 40.6 0.6 2.4e-08 33.4 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 ELFV_dehydrog PF00208.16 EDN93254.1 - 7.2e-86 287.7 4.9 9.1e-86 287.3 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EDN93254.1 - 4.6e-48 162.0 0.0 2e-47 160.0 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EDN93254.1 - 0.015 15.5 0.1 0.044 14.0 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Aldo_ket_red PF00248.16 EDN93255.1 - 7e-45 153.0 0.0 8.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABM PF03992.11 EDN93257.1 - 0.12 12.4 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Glyco_hydro_71 PF03659.9 EDN93259.1 - 1.1e-152 508.0 3.1 1.5e-152 507.5 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.13 EDN93260.1 - 7.4e-14 51.2 0.0 1.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.8 EDN93261.1 - 1.7 8.4 6.2 1.7 8.4 4.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_1 PF00232.13 EDN93263.1 - 1.5e-83 280.5 5.4 2.6e-64 217.0 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Ferritin_2 PF13668.1 EDN93264.1 - 2.1e-41 141.0 0.9 2.1e-41 141.0 0.6 1.7 2 0 0 2 2 2 1 Ferritin-like domain RNB PF00773.14 EDN93265.1 - 3.3e-88 296.1 0.0 9e-88 294.6 0.0 1.8 1 0 0 1 1 1 1 RNB domain AAA_7 PF12775.2 EDN93265.1 - 0.15 11.1 0.0 2.9 6.8 0.0 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region D3 GLE1 PF07817.8 EDN93266.1 - 1.3e-25 89.7 0.2 1.5e-24 86.3 0.0 2.5 2 1 0 2 2 2 1 GLE1-like protein PAT1 PF09770.4 EDN93266.1 - 0.6 8.2 33.8 0.78 7.9 23.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 EDN93266.1 - 2.9 6.2 8.3 4.6 5.5 5.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADH_N PF08240.7 EDN93269.1 - 1.7e-22 79.2 4.8 2.9e-22 78.4 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN93269.1 - 7.4e-16 57.8 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN93269.1 - 0.00032 21.6 0.0 0.00051 20.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EDN93269.1 - 0.04 14.0 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EDN93269.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HMA PF00403.21 EDN93271.1 - 1e-07 31.9 0.0 2.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain AsnC_trans_reg PF01037.16 EDN93271.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AsnC family DUF1768 PF08719.6 EDN93274.1 - 2.1e-30 105.5 0.3 4.3e-30 104.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ferric_reduct PF01794.14 EDN93274.1 - 4.3e-14 52.6 5.0 4.3e-14 52.6 3.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDN93274.1 - 3.2e-11 43.0 0.1 1.6e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN93274.1 - 3.8e-09 36.6 0.3 7.8e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Catalase PF00199.14 EDN93275.1 - 6.8e-157 522.0 2.3 8.7e-157 521.7 1.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN93275.1 - 4.3e-11 42.5 0.0 1.7e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive IglC PF11550.3 EDN93276.1 - 0.0088 15.3 0.1 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Intracellular growth locus C protein FATC PF02260.15 EDN93276.1 - 1.1 8.7 3.3 1.1 8.7 0.5 2.3 2 0 0 2 2 2 0 FATC domain Amidohydro_2 PF04909.9 EDN93277.1 - 3.5e-19 69.4 0.1 4.5e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase APH PF01636.18 EDN93278.1 - 1.7e-18 67.2 0.0 2.3e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN93278.1 - 0.00073 18.9 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EDN93278.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EDN93278.1 - 0.017 14.1 0.0 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4234 PF14018.1 EDN93278.1 - 0.082 12.6 0.3 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) adh_short PF00106.20 EDN93280.1 - 7.6e-18 64.9 0.0 4.2e-16 59.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN93280.1 - 2.1e-07 30.7 0.0 0.00071 19.2 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EDN93280.1 - 1.4e-05 24.9 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN93280.1 - 0.023 14.1 0.0 0.078 12.3 0.0 1.9 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BTB PF00651.26 EDN93281.1 - 1e-07 31.8 0.1 2.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4535 PF15054.1 EDN93283.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF3735 PF12537.3 EDN93284.1 - 0.024 14.6 0.0 0.088 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) PBP1_TM PF14812.1 EDN93286.1 - 0.082 13.2 0.6 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3403 PF11883.3 EDN93287.1 - 0.094 12.9 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) Ribosomal_S14 PF00253.16 EDN93288.1 - 6.8e-18 63.7 0.4 1.3e-17 62.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.6 EDN93288.1 - 0.1 12.0 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 QLQ Arb2 PF09757.4 EDN93289.1 - 4.6e-28 97.8 0.0 6.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Amidoligase_2 PF12224.3 EDN93291.1 - 5.8e-28 98.1 0.3 2.1e-21 76.6 0.0 2.4 1 1 0 2 2 2 2 Putative amidoligase enzyme DUF3595 PF12166.3 EDN93292.1 - 0.007 15.2 0.2 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3595) DUF3149 PF11346.3 EDN93292.1 - 0.53 9.8 4.1 0.7 9.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF3425 PF11905.3 EDN93293.1 - 3e-26 91.9 0.0 9.3e-26 90.3 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) RVT_1 PF00078.22 EDN93294.1 - 3e-26 92.0 0.0 3.5e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PG_binding_3 PF09374.5 EDN93294.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.7 1 1 0 1 1 1 0 Predicted Peptidoglycan domain Tox-MPTase3 PF15639.1 EDN93294.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 WD40 PF00400.27 EDN93296.1 - 1.1e-09 37.8 18.9 0.00019 21.1 0.5 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EDN93296.1 - 0.0011 19.2 0.3 0.9 9.9 0.1 4.0 3 1 1 4 4 4 1 PQQ-like domain PQQ_2 PF13360.1 EDN93296.1 - 0.0032 16.9 0.0 0.023 14.1 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain eIF3_subunit PF08597.5 EDN93296.1 - 0.048 13.2 0.3 0.069 12.7 0.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spherulin4 PF12138.3 EDN93297.1 - 4e-53 180.4 0.2 4.5e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 zf-RING_4 PF14570.1 EDN93299.1 - 0.038 13.5 0.2 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PAN_1 PF00024.21 EDN93300.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.1 EDN93300.1 - 0.02 14.6 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 PAN domain HET PF06985.6 EDN93301.1 - 4.1e-33 114.4 3.2 8.5e-33 113.4 2.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SOG2 PF10428.4 EDN93302.1 - 0.21 10.2 5.4 0.22 10.1 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.8 EDN93302.1 - 0.38 10.8 6.1 1.4 8.9 3.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EDN93302.1 - 7.9 4.6 9.5 8.8 4.4 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein BTB PF00651.26 EDN93304.1 - 9.7e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF1447 PF07288.6 EDN93304.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) HTH_Tnp_Tc3_2 PF01498.13 EDN93305.1 - 0.05 13.6 0.7 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Transposase BTB PF00651.26 EDN93307.1 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TP_methylase PF00590.15 EDN93311.1 - 3.4e-43 147.8 0.1 5.5e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EDN93311.1 - 5e-06 25.7 0.0 9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal DASH_Spc19 PF08287.6 EDN93312.1 - 2.1e-47 160.5 5.1 2.8e-47 160.1 3.6 1.1 1 0 0 1 1 1 1 Spc19 Sec20 PF03908.8 EDN93312.1 - 0.25 11.0 1.5 9.3 6.0 0.1 2.5 1 1 1 2 2 2 0 Sec20 Radical_SAM PF04055.16 EDN93313.1 - 1.1e-12 48.4 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_2 PF02230.11 EDN93314.1 - 3.7e-16 59.2 0.4 1.6e-15 57.1 0.2 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDN93314.1 - 4.3e-07 29.7 0.2 1.5e-06 28.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN93314.1 - 0.0015 18.4 0.3 0.0052 16.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDN93314.1 - 0.0065 16.0 0.3 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold AP_endonuc_2 PF01261.19 EDN93317.1 - 5.6e-19 68.2 0.0 9.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.13 EDN93318.1 - 1.3e-22 79.9 0.1 2.2e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN93318.1 - 3.9e-08 33.0 14.6 6.7e-08 32.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EDN93320.1 - 1.6e-45 155.5 0.0 4.8e-45 153.9 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EDN93320.1 - 2.4e-16 59.5 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EDN93320.1 - 3.4e-14 53.0 0.2 1.1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 EDN93320.1 - 3.8e-13 49.6 0.0 1.1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EDN93320.1 - 0.099 13.0 0.6 0.52 10.7 0.0 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent SinI PF08671.5 EDN93320.1 - 0.2 11.1 0.0 15 5.1 0.0 2.7 2 0 0 2 2 2 0 Anti-repressor SinI Sugar_tr PF00083.19 EDN93321.1 - 2.7e-126 421.7 27.1 3.1e-126 421.5 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93321.1 - 2.3e-19 69.3 41.3 1.1e-17 63.8 20.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 EDN93322.1 - 7.4e-23 80.4 0.0 1.3e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EDN93322.1 - 3.9e-11 43.1 0.0 6.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.20 EDN93323.1 - 2.5e-69 233.5 0.0 3.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pribosyltran_N PF13793.1 EDN93324.1 - 3.2e-42 142.9 0.1 2.4e-40 136.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDN93324.1 - 2.8e-33 115.1 0.0 2.8e-29 102.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDN93324.1 - 1.7e-07 31.0 0.0 2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.2 EDN93325.1 - 1.4e-56 191.7 0.0 2.6e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EDN93325.1 - 0.028 14.4 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 XPG I-region Isochorismatase PF00857.15 EDN93327.1 - 1.2e-20 74.1 0.0 1.5e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DAO PF01266.19 EDN93328.1 - 2.6e-13 49.6 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDN93328.1 - 0.00048 18.8 0.1 0.001 17.7 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EDN93328.1 - 0.0008 18.3 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EDN93328.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN93328.1 - 0.042 13.6 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ECH PF00378.15 EDN93330.1 - 0.00013 21.2 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 EDN93331.1 - 1.9e-25 89.4 0.1 2.1e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Exo_endo_phos_2 PF14529.1 EDN93336.1 - 1.3e-22 79.6 1.2 3.1e-22 78.4 0.9 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN93336.1 - 1.5e-05 25.0 0.7 2.2e-05 24.5 0.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EDN93337.1 - 8.9e-15 55.1 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN93337.1 - 8.5e-12 44.8 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Collagen PF01391.13 EDN93337.1 - 0.00066 19.1 6.3 0.00066 19.1 4.4 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-RVT PF13966.1 EDN93337.1 - 0.0081 16.4 0.2 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.17 EDN93338.1 - 2.6e-13 49.3 0.0 2.6e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3466 PF11949.3 EDN93341.1 - 0.0042 15.7 1.1 0.0054 15.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3466) rve PF00665.21 EDN93342.1 - 2.9e-08 33.8 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN93342.1 - 8.7e-05 22.0 0.3 0.00026 20.5 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN93342.1 - 0.032 13.9 0.2 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Glyco_transf_25 PF01755.12 EDN93345.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) HTH_Tnp_Tc5 PF03221.11 EDN93346.1 - 1.4e-10 40.8 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDN93346.1 - 0.039 12.8 0.1 0.053 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Rsm22 PF09243.5 EDN93347.1 - 2.8e-31 108.5 0.0 1.8e-28 99.3 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Pectate_lyase_3 PF12708.2 EDN93350.1 - 8.9e-86 287.6 18.6 1.8e-70 237.5 6.9 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EDN93350.1 - 2.5e-07 30.0 0.4 0.018 14.5 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Opi1 PF08618.5 EDN93350.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 Sugar_tr PF00083.19 EDN93351.1 - 1.2e-88 297.7 29.8 1.4e-88 297.5 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93351.1 - 1.8e-22 79.5 52.9 2.2e-18 66.1 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EDN93351.1 - 0.0035 15.4 13.6 0.0076 14.3 0.2 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family NHL PF01436.16 EDN93353.1 - 0.003 17.4 0.9 0.025 14.5 0.1 2.6 2 0 0 2 2 2 1 NHL repeat SGL PF08450.7 EDN93353.1 - 0.041 13.2 0.7 0.83 8.9 0.1 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Adeno_E4 PF05385.6 EDN93354.1 - 0.13 12.2 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Pyr_redox_3 PF13738.1 EDN93355.1 - 3.3e-22 79.5 0.0 2e-21 77.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN93355.1 - 6.8e-16 57.5 0.1 2.1e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN93355.1 - 4.7e-08 32.3 0.2 4.3e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN93355.1 - 7.4e-05 22.7 0.0 0.017 15.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN93355.1 - 0.00074 19.8 0.0 0.055 13.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN93355.1 - 0.004 17.1 0.0 0.85 9.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EDN93355.1 - 0.013 15.6 0.0 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDN93355.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EDN93355.1 - 0.037 12.9 0.1 6.6 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 EDN93355.1 - 0.057 12.4 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DDE_1 PF03184.14 EDN93356.1 - 5.7e-13 48.5 0.4 1.5e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93356.1 - 1.3e-12 47.0 0.2 3.6e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDN93356.1 - 0.021 14.6 0.4 0.28 11.0 0.0 2.7 2 0 0 2 2 2 0 NUMOD1 domain HTH_Tnp_Tc5 PF03221.11 EDN93356.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF3373 PF11853.3 EDN93357.1 - 0.047 12.2 0.7 0.045 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Nucleo_P87 PF07267.6 EDN93357.1 - 1.1 7.8 5.2 1.2 7.7 3.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2098 PF09871.4 EDN93357.1 - 1.2 9.0 4.9 1.8 8.5 3.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Med9 PF07544.8 EDN93357.1 - 3.6 7.3 10.7 0.55 9.9 1.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HTH_psq PF05225.11 EDN93358.1 - 1.3e-08 34.2 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDN93358.1 - 0.0023 17.7 0.1 0.0049 16.6 0.0 1.6 2 0 0 2 2 2 1 NUMOD1 domain SpoIIID PF12116.3 EDN93358.1 - 0.061 13.2 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D PhoU_div PF01865.11 EDN93358.1 - 0.072 12.2 0.2 0.082 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF47 HMG_box_5 PF14887.1 EDN93358.1 - 0.13 12.0 0.1 0.4 10.4 0.0 1.7 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Pro-kuma_activ PF09286.6 EDN93359.1 - 2e-36 125.1 1.9 2.3e-36 124.9 0.2 1.9 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN93359.1 - 2.1e-05 23.8 0.7 2.1e-05 23.8 0.5 2.2 2 0 0 2 2 2 1 Subtilase family DNA_primase_lrg PF04104.9 EDN93359.1 - 0.0044 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Perilipin PF03036.11 EDN93359.1 - 0.015 14.1 0.1 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Perilipin family Pil1 PF13805.1 EDN93360.1 - 8.8e-149 494.0 0.8 1.1e-148 493.7 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EDN93360.1 - 0.027 13.8 4.1 0.03 13.6 0.8 2.3 2 1 0 3 3 3 0 FAM92 protein LSM PF01423.17 EDN93361.1 - 3.4e-06 26.5 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain XPG_N PF00752.12 EDN93362.1 - 3.1e-31 107.6 0.0 9.4e-31 106.0 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDN93362.1 - 5.6e-27 93.6 0.0 1.4e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EDN93362.1 - 5.3e-05 22.4 14.0 0.0063 15.9 0.9 4.8 3 0 0 3 3 3 2 Ubiquitin interaction motif DUF2477 PF10631.4 EDN93362.1 - 0.18 12.0 0.1 0.5 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Glyco_hydro_92 PF07971.7 EDN93363.1 - 5e-113 378.4 0.3 5.7e-113 378.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DDE_1 PF03184.14 EDN93367.1 - 2.8e-36 124.7 0.0 5e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN93367.1 - 1e-12 47.6 0.1 1e-11 44.4 0.1 2.6 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN93367.1 - 3.3e-06 26.9 0.0 7.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93367.1 - 0.0048 16.4 0.4 0.012 15.1 0.1 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain MarR_2 PF12802.2 EDN93367.1 - 0.012 15.2 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_AsnC-type PF13404.1 EDN93367.1 - 0.019 14.4 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.1 EDN93367.1 - 0.023 14.6 0.1 0.096 12.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0180 PF03698.8 EDN93367.1 - 0.036 13.9 0.2 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF3400 PF11880.3 EDN93367.1 - 0.044 13.0 0.0 0.55 9.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3400) HTH_24 PF13412.1 EDN93367.1 - 0.058 12.7 0.1 0.45 9.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_6 PF01418.12 EDN93367.1 - 0.06 13.0 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family p450 PF00067.17 EDN93368.1 - 3.2e-63 213.8 0.2 3.9e-63 213.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN93369.1 - 2.7e-41 141.5 0.1 3.5e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EDN93370.1 - 0.00034 20.3 0.1 0.0037 17.0 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Acyl_transf_1 PF00698.16 EDN93371.1 - 2.7e-52 178.0 0.0 6.6e-51 173.5 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EDN93371.1 - 9.1e-45 152.5 0.0 3e-44 150.8 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EDN93371.1 - 1.1e-40 139.3 0.0 3e-40 137.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EDN93371.1 - 4.9e-38 130.9 0.0 7.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EDN93371.1 - 2.8e-31 107.8 0.1 6e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EDN93371.1 - 4.4e-28 98.4 0.0 1.1e-27 97.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.7 EDN93371.1 - 9.9e-17 61.2 0.0 5.1e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN93371.1 - 5.2e-12 45.6 0.0 3.7e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN93371.1 - 1e-10 41.5 0.0 2.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN93371.1 - 1.1e-10 41.7 0.0 3.5e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN93371.1 - 3.7e-07 30.7 0.0 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EDN93371.1 - 3e-05 24.1 0.0 9.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EDN93371.1 - 4.6e-05 22.6 0.0 9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EDN93371.1 - 0.00024 20.6 0.0 0.00061 19.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase p450 PF00067.17 EDN93372.1 - 6e-33 114.0 0.0 8.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EDN93373.1 - 5.1e-17 61.9 0.0 1.8e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EDN93373.1 - 0.002 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EDN93373.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein KR PF08659.5 EDN93374.1 - 2.7e-53 180.3 0.0 8.7e-53 178.6 0.0 1.9 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EDN93374.1 - 8e-53 179.5 0.0 1.2e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EDN93374.1 - 1e-50 172.8 0.0 1.7e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EDN93374.1 - 2.1e-50 171.5 0.2 7.6e-32 110.7 0.0 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EDN93374.1 - 8.4e-42 142.9 0.2 3.5e-41 140.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDN93374.1 - 1.8e-35 121.3 0.1 1.2e-34 118.7 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EDN93374.1 - 6.2e-18 64.6 0.0 1.7e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EDN93374.1 - 1.3e-05 25.3 0.2 3.6e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EDN93374.1 - 0.0002 21.0 0.0 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDN93374.1 - 0.00061 20.6 0.0 0.0028 18.5 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EDN93374.1 - 0.0035 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lactamase_B_3 PF13483.1 EDN93374.1 - 0.077 12.6 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Thioesterase PF00975.15 EDN93375.1 - 3.4e-13 50.3 0.0 3.9e-13 50.1 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EDN93375.1 - 1.2e-05 25.2 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93375.1 - 0.00017 21.3 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDN93375.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transferase PF02458.10 EDN93376.1 - 1.8e-15 56.3 0.0 1e-12 47.2 0.0 3.0 2 1 0 2 2 2 2 Transferase family zf-RING_2 PF13639.1 EDN93381.1 - 2.6e-08 33.5 9.2 2.6e-08 33.5 6.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN93381.1 - 0.00036 20.1 8.1 0.00036 20.1 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN93381.1 - 0.00098 18.8 9.1 0.00098 18.8 6.3 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN93381.1 - 0.0022 17.9 11.4 0.0022 17.9 7.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN93381.1 - 0.004 17.2 5.5 0.004 17.2 3.8 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDN93381.1 - 0.11 12.1 9.3 0.27 10.9 5.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EDN93381.1 - 1.9 8.5 9.2 81 3.2 6.4 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain Hydrophobin_2 PF06766.6 EDN93382.1 - 5.2e-24 83.6 12.6 6.4e-24 83.4 8.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_12 PF01670.11 EDN93384.1 - 1.4e-16 60.6 0.2 2.2e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Rad9_Rad53_bind PF08605.5 EDN93384.1 - 0.11 12.2 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Glyco_hydro_61 PF03443.9 EDN93385.1 - 4.3e-63 213.0 0.2 4.3e-63 213.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EDN93385.1 - 5.6e-12 45.1 8.8 1.6e-11 43.6 6.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_transf_28 PF03033.15 EDN93386.1 - 1.3e-24 86.5 0.0 3.6e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EDN93386.1 - 1.9e-06 26.7 0.0 3.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.10 EDN93386.1 - 0.042 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger ATG_C PF09333.6 EDN93386.1 - 0.081 13.0 0.0 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 ATG C terminal domain WD40 PF00400.27 EDN93387.1 - 1e-28 98.1 4.1 2.3e-08 33.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN93387.1 - 1.1e-05 25.2 0.1 0.039 13.6 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EDN93387.1 - 0.077 12.5 0.2 0.31 10.6 0.1 2.1 1 0 0 1 1 1 0 HIRA B motif ABC_tran PF00005.22 EDN93389.1 - 1.8e-51 174.0 0.0 4.6e-31 107.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN93389.1 - 2.3e-24 86.2 35.4 1.7e-15 57.1 12.2 4.6 4 1 1 5 5 5 3 ABC transporter transmembrane region SMC_N PF02463.14 EDN93389.1 - 3.9e-09 36.0 0.8 8.4e-05 21.8 0.1 4.0 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EDN93389.1 - 7.1e-06 25.5 0.0 0.013 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDN93389.1 - 8.8e-05 22.5 1.1 0.031 14.2 0.2 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EDN93389.1 - 0.00026 20.4 0.2 0.84 9.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SE PF00437.15 EDN93389.1 - 0.00097 18.1 0.0 0.61 8.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EDN93389.1 - 0.0015 18.9 0.0 0.11 12.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EDN93389.1 - 0.0021 17.2 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN93389.1 - 0.004 17.2 0.2 8.9 6.4 0.1 3.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EDN93389.1 - 0.019 14.9 0.1 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EDN93389.1 - 0.02 14.8 0.7 0.5 10.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain Miro PF08477.8 EDN93389.1 - 0.022 15.2 0.1 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 EDN93389.1 - 0.023 14.5 2.8 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 EDN93389.1 - 0.049 13.2 1.1 9.8 5.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EDN93389.1 - 0.053 12.4 0.1 0.92 8.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 EDN93389.1 - 0.054 12.9 0.6 4 6.8 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EDN93389.1 - 0.072 12.1 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 EDN93389.1 - 0.091 12.6 0.1 3.6 7.5 0.0 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EDN93394.1 - 2e-46 157.7 0.1 3.3e-30 105.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN93394.1 - 1.9e-28 99.6 20.7 2.2e-14 53.5 8.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EDN93394.1 - 8.3e-14 52.2 0.1 0.0001 22.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN93394.1 - 2.1e-12 46.7 2.3 1.5e-05 24.3 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EDN93394.1 - 9.6e-07 28.3 0.2 0.0032 16.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN93394.1 - 1.2e-06 28.9 0.3 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN93394.1 - 2.9e-06 27.4 0.1 0.026 14.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDN93394.1 - 6.7e-06 26.2 0.8 0.2 11.6 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDN93394.1 - 0.0018 17.7 8.5 0.012 15.0 1.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EDN93394.1 - 0.0024 17.7 0.0 2 8.4 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EDN93394.1 - 0.0034 16.8 0.3 0.11 11.8 0.1 3.0 3 1 0 4 4 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EDN93394.1 - 0.0065 15.9 0.1 1 8.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EDN93394.1 - 0.012 15.5 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 EDN93394.1 - 0.015 14.2 1.8 1.8 7.3 0.5 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EDN93394.1 - 0.017 15.6 0.0 9.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EDN93394.1 - 0.022 14.4 0.1 9.5 5.8 0.1 3.2 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 EDN93394.1 - 0.024 14.3 0.3 0.47 10.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EDN93394.1 - 0.025 13.7 0.2 0.27 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EDN93394.1 - 0.026 14.3 1.8 0.063 13.0 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EDN93394.1 - 0.031 14.4 0.3 4.2 7.5 0.0 3.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDN93394.1 - 0.038 14.2 0.1 5.6 7.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN93394.1 - 0.049 13.3 0.7 5.9 6.7 0.1 3.2 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 EDN93394.1 - 0.081 12.7 0.4 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EDN93394.1 - 0.099 12.1 0.4 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EDN93394.1 - 0.16 11.8 0.1 2.7 7.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN93394.1 - 0.17 12.0 0.1 28 4.9 0.0 3.8 5 0 0 5 5 3 0 RNA helicase Zot PF05707.7 EDN93394.1 - 0.18 11.2 0.2 1.1 8.7 0.0 2.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EDN93394.1 - 0.19 12.5 0.0 4.8 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EDN93394.1 - 1.7 7.0 1.5 2.5 6.4 0.0 1.9 3 0 0 3 3 3 0 AAA domain RAMP4 PF06624.7 EDN93394.1 - 4.7 6.8 6.1 0.91 9.1 0.0 2.7 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 Spc7_N PF15402.1 EDN93395.1 - 3e-284 945.5 77.8 2.2e-158 529.0 24.4 2.5 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EDN93395.1 - 9.9e-123 408.9 9.4 1.6e-122 408.2 6.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EDN93395.1 - 3.5e-21 74.6 1.3 6.9e-21 73.6 0.9 1.5 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17 PF00366.15 EDN93396.1 - 7.2e-30 102.8 0.4 1.2e-29 102.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Aldo_ket_red PF00248.16 EDN93400.1 - 4.6e-12 45.3 0.1 5.3e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1908 PF08926.6 EDN93400.1 - 0.052 12.2 0.3 0.054 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Macoilin PF09726.4 EDN93400.1 - 0.074 11.3 1.2 0.075 11.3 0.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Mac PF12464.3 EDN93400.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase Tannase PF07519.6 EDN93401.1 - 1.4e-97 327.3 0.0 1.7e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EDN93401.1 - 8.5e-05 22.5 0.0 0.00056 19.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN93401.1 - 0.002 17.3 0.1 0.62 9.2 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pro-kuma_activ PF09286.6 EDN93402.1 - 3.3e-41 140.6 0.3 5.1e-41 140.0 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN93402.1 - 3.4e-13 49.4 0.0 1.1e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Subtilase family HsbA PF12296.3 EDN93404.1 - 1.8e-23 82.6 4.7 2.8e-23 82.0 3.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Endonuc-BglII PF09195.6 EDN93406.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.4 2 0 0 2 2 2 0 Restriction endonuclease BglII Strumpellin PF10266.4 EDN93406.1 - 0.11 9.8 0.1 0.14 9.5 0.1 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin dDENN PF03455.14 EDN93409.1 - 0.047 13.7 0.0 0.92 9.6 0.0 2.2 1 1 1 2 2 2 0 dDENN domain DUF2592 PF10766.4 EDN93409.1 - 0.2 11.0 0.7 0.87 8.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) DDE_1 PF03184.14 EDN93411.1 - 8.8e-64 214.6 0.0 1.4e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93411.1 - 2.1e-15 55.9 0.0 3.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN93411.1 - 1.9e-11 43.6 0.1 4.5e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN93411.1 - 1.2e-08 34.8 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDN93411.1 - 0.02 14.8 0.9 0.091 12.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN93411.1 - 0.026 14.1 0.0 0.1 12.2 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain tRNA_anti_2 PF13742.1 EDN93413.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain HSP70 PF00012.15 EDN93414.1 - 2.2e-82 276.8 1.6 2.2e-82 276.8 1.1 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDN93414.1 - 1.5e-09 36.9 0.1 2.6e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Afi1 PF07792.7 EDN93414.1 - 0.13 12.3 2.2 0.18 11.8 0.4 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SprT-like PF10263.4 EDN93415.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Acetyltransf_1 PF00583.19 EDN93417.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN93417.1 - 4.4e-07 29.9 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN93417.1 - 0.00071 19.6 0.0 0.00086 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN93417.1 - 0.057 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AATase PF07247.7 EDN93424.1 - 0.047 12.2 0.1 0.047 12.2 0.1 1.0 1 0 0 1 1 1 0 Alcohol acetyltransferase Methyltransf_23 PF13489.1 EDN93425.1 - 0.036 13.7 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 EDN93427.1 - 1.3e-120 403.0 27.0 1.5e-120 402.8 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93427.1 - 5.3e-23 81.3 28.6 4.2e-20 71.7 1.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EDN93428.1 - 0.063 12.4 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF2860 PF11059.3 EDN93428.1 - 0.099 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) AMP-binding PF00501.23 EDN93429.1 - 2.1e-84 283.3 0.0 2.5e-47 161.2 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN93429.1 - 2.7e-13 50.6 0.0 5.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OPT PF03169.10 EDN93430.1 - 1.1e-121 407.2 42.3 1.3e-121 407.0 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EDN93431.1 - 3.9e-140 468.2 39.0 4.5e-140 468.0 27.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VWA_3 PF13768.1 EDN93434.1 - 1.5e-30 105.9 0.0 2.5e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EDN93434.1 - 1.6e-10 41.3 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDN93434.1 - 2.2e-07 30.7 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glycos_transf_2 PF00535.21 EDN93434.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 VWA_CoxE PF05762.9 EDN93434.1 - 0.035 13.2 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EDN93434.1 - 0.17 11.6 0.1 1.2 8.9 0.0 2.0 1 1 0 1 1 1 0 vWA found in TerF C terminus Med8 PF10232.4 EDN93438.1 - 1.2e-25 90.3 0.2 1.4e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4612 PF15389.1 EDN93438.1 - 0.052 14.1 3.0 0.096 13.3 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) SDA1 PF05285.7 EDN93438.1 - 0.5 9.5 11.3 0.73 9.0 7.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EDN93438.1 - 5.9 4.6 9.6 8 4.2 6.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EDN93439.1 - 0.17 10.9 20.7 0.17 10.9 14.4 1.0 1 0 0 1 1 1 0 BUD22 Sec62 PF03839.11 EDN93439.1 - 0.88 8.9 7.6 1 8.6 5.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 EDN93439.1 - 1.2 8.8 9.1 1.3 8.7 6.3 1.0 1 0 0 1 1 1 0 DDHD domain DUF1777 PF08648.7 EDN93439.1 - 1.4 8.6 18.9 1.5 8.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FYDLN_acid PF09538.5 EDN93439.1 - 1.6 9.3 18.6 1.8 9.1 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Trypan_PARP PF05887.6 EDN93439.1 - 2 8.2 28.1 2.3 8.0 19.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trypan_glycop_C PF10659.4 EDN93439.1 - 2.1 8.6 10.4 2.7 8.3 7.2 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DUF2956 PF11169.3 EDN93439.1 - 3.5 7.6 7.1 4.2 7.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF2457 PF10446.4 EDN93439.1 - 4.9 5.7 25.6 5.3 5.6 17.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 EDN93439.1 - 5 6.4 20.4 5.3 6.3 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DHHW PF14286.1 EDN93439.1 - 5.2 6.2 6.9 5.5 6.2 4.8 1.0 1 0 0 1 1 1 0 DHHW protein YqfQ PF14181.1 EDN93439.1 - 5.6 6.9 15.4 6.4 6.8 10.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein MIP-T3 PF10243.4 EDN93439.1 - 5.8 5.2 23.5 6.2 5.1 16.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CKAP2_C PF15297.1 EDN93439.1 - 6.2 5.5 14.0 6.5 5.4 9.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Peptidase_U57 PF05582.7 EDN93439.1 - 8.8 5.1 6.2 10 5.0 4.3 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3464 PF11947.3 EDN93439.1 - 9.6 5.6 5.8 11 5.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AIF_C PF14721.1 EDN93439.1 - 9.7 6.4 7.9 11 6.2 5.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vfa1 PF08432.5 EDN93439.1 - 9.9 6.1 14.0 11 5.9 9.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PQ-loop PF04193.9 EDN93440.1 - 1.1e-20 72.9 11.1 8.7e-13 47.6 2.3 2.7 3 0 0 3 3 3 2 PQ loop repeat DUF3112 PF11309.3 EDN93440.1 - 0.06 13.1 0.5 0.52 10.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Swi3 PF07962.7 EDN93441.1 - 0.033 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 2OG-FeII_Oxy_3 PF13640.1 EDN93443.1 - 8.1e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EDN93443.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDN93443.1 - 4.6e-05 23.6 0.0 7.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EDN93444.1 - 3.3e-22 79.1 0.0 4.1e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN93444.1 - 7.8e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN93444.1 - 2e-07 31.0 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.17 EDN93445.1 - 9.1e-15 54.0 0.2 2.1e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN93445.1 - 3.4e-14 52.5 0.0 2.5e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EDN93445.1 - 5.4e-11 42.0 2.1 1.1e-10 41.0 1.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDN93445.1 - 1.1e-08 34.8 0.8 3.4e-08 33.2 0.5 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EDN93445.1 - 7.6e-06 25.6 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EDN93445.1 - 0.0001 21.3 0.8 0.00024 20.1 0.6 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.8 EDN93445.1 - 0.0011 18.2 2.9 0.0029 16.8 2.0 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.3 EDN93445.1 - 0.0022 18.0 0.4 0.007 16.4 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 EDN93445.1 - 0.19 11.4 22.7 1.1 8.9 8.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MoaE PF02391.12 EDN93446.1 - 2.9e-33 114.1 0.0 4.1e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 MoaE protein Sugar_tr PF00083.19 EDN93447.1 - 8e-43 146.6 30.7 7.3e-42 143.4 21.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93447.1 - 3.1e-15 55.7 32.4 1.8e-08 33.4 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FLILHELTA PF10306.4 EDN93447.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA DUF606 PF04657.8 EDN93447.1 - 1.6 8.8 19.7 0.33 11.0 2.7 3.7 2 2 1 3 3 3 0 Protein of unknown function, DUF606 RVT_1 PF00078.22 EDN93452.1 - 1.6e-34 119.1 1.8 3e-34 118.2 1.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN93452.1 - 1.3e-19 69.9 0.7 4.3e-19 68.2 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN93452.1 - 4.8e-13 49.5 0.6 1.9e-12 47.6 0.1 2.3 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EDN93452.1 - 2.3e-05 24.4 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDN93452.1 - 0.074 12.7 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Collagen PF01391.13 EDN93453.1 - 9.9e-05 21.8 3.4 0.00014 21.3 2.4 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-RING-like PF08746.6 EDN93453.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 RING-like domain RVT_1 PF00078.22 EDN93454.1 - 0.0031 16.8 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN93455.1 - 0.0085 15.7 0.6 0.021 14.4 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase YccV-like PF08755.6 EDN93456.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like DDE_1 PF03184.14 EDN93457.1 - 3.3e-10 39.4 0.0 9.6e-10 37.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93457.1 - 1.2e-09 37.5 0.0 1.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN93457.1 - 0.036 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EDN93457.1 - 0.043 13.7 0.2 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D UPF0175 PF03683.8 EDN93457.1 - 0.065 12.7 0.1 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_23 PF13384.1 EDN93457.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF3433 PF11915.3 EDN93458.1 - 1.3e-31 108.5 10.4 8.9e-27 93.0 0.6 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) LEP503 PF15221.1 EDN93462.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.3 1 1 0 1 1 1 0 Lens epithelial cell protein LEP503 Aldo_ket_red PF00248.16 EDN93463.1 - 1.3e-24 86.5 0.0 1.6e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HypA PF01155.14 EDN93465.1 - 0.14 11.8 0.1 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RNA_pol_I_A49 PF06870.7 EDN93466.1 - 1 7.8 3.9 4.1 5.8 1.2 2.1 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor SNARE PF05739.14 EDN93468.1 - 8.9e-18 63.7 6.0 9.6e-18 63.6 0.3 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EDN93468.1 - 5.4e-17 61.8 1.8 5.4e-17 61.8 1.2 3.1 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EDN93468.1 - 0.011 15.2 0.3 0.011 15.2 0.2 2.8 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 EDN93468.1 - 0.016 15.1 1.9 1 9.3 0.1 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Syntaxin-18_N PF10496.4 EDN93468.1 - 0.031 14.1 2.6 0.13 12.1 0.1 2.8 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 EDN93468.1 - 0.16 12.2 8.5 2.5 8.3 0.1 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EDN93468.1 - 0.18 10.2 7.2 0.13 10.6 3.3 1.8 2 0 0 2 2 2 0 AAA domain KxDL PF10241.4 EDN93468.1 - 0.67 9.8 4.1 6.1 6.8 0.1 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein BLOC1_2 PF10046.4 EDN93468.1 - 1 9.5 4.8 11 6.1 0.1 3.0 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoLp-III PF07464.6 EDN93468.1 - 2.3 8.2 8.3 3.1 7.7 0.7 3.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.6 EDN93468.1 - 6.6 5.2 10.1 0.17 10.5 1.5 2.1 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2299 PF10061.4 EDN93469.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) EBP50_C-term PF09007.6 EDN93469.1 - 0.37 10.6 1.6 4.3 7.2 0.2 2.3 2 0 0 2 2 2 0 EBP50, C-terminal F-box PF00646.28 EDN93471.1 - 0.016 14.8 0.1 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EDN93471.1 - 0.019 14.9 0.5 0.27 11.2 0.0 2.6 1 1 1 2 2 2 0 PRANC domain Glyco_hydro_47 PF01532.15 EDN93472.1 - 5.8e-168 559.2 0.0 6.8e-168 558.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Podoplanin PF05808.6 EDN93473.1 - 0.00098 18.7 1.2 0.0018 17.8 0.8 1.4 1 0 0 1 1 1 1 Podoplanin RCR PF12273.3 EDN93473.1 - 0.032 14.7 0.2 0.1 13.1 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red VSP PF03302.8 EDN93473.1 - 0.033 12.8 6.6 0.089 11.4 4.6 1.6 1 1 1 2 2 2 0 Giardia variant-specific surface protein I-set PF07679.11 EDN93473.1 - 0.083 12.7 0.4 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF1180 PF06679.7 EDN93473.1 - 0.14 12.0 1.1 0.24 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Med3 PF11593.3 EDN93473.1 - 2 7.5 8.3 2.8 7.0 5.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RVT_1 PF00078.22 EDN93475.1 - 5.1e-34 117.5 0.0 1e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN93475.1 - 0.00029 21.1 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN93481.1 - 3.5e-34 118.0 0.9 7.1e-34 117.0 0.6 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN93481.1 - 9.4e-12 45.4 0.0 2.7e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN93481.1 - 0.00022 20.7 0.1 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN93481.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4470 PF14737.1 EDN93482.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) DUF972 PF06156.8 EDN93483.1 - 0.011 16.0 2.0 0.026 14.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EDN93483.1 - 0.02 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 EDN93483.1 - 0.035 12.0 1.5 0.059 11.2 0.0 2.1 3 0 0 3 3 3 0 Hsp70 protein V-SNARE PF05008.10 EDN93483.1 - 0.12 12.5 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CENP-F_leu_zip PF10473.4 EDN93483.1 - 0.13 12.1 1.6 0.24 11.2 1.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 EDN93483.1 - 0.14 12.3 2.2 0.29 11.2 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Rootletin PF15035.1 EDN93483.1 - 0.52 10.2 6.0 1.1 9.1 4.2 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SRF-TF PF00319.13 EDN93485.1 - 0.00018 20.6 0.0 0.00041 19.5 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NAD_binding_6 PF08030.7 EDN93487.1 - 7.6e-09 35.6 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN93487.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain Corona_NS8 PF12093.3 EDN93487.1 - 0.0043 17.3 0.0 0.36 11.2 0.0 2.1 1 1 1 2 2 2 1 Coronavirus NS8 protein Pkinase PF00069.20 EDN93488.1 - 2.1e-08 33.6 0.0 3.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93488.1 - 0.00043 19.4 0.0 0.0007 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN93488.1 - 0.0047 16.7 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3435 PF11917.3 EDN93491.1 - 2.9e-55 187.6 0.1 4.7e-55 186.9 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN93491.1 - 0.0036 16.9 0.4 0.021 14.4 0.1 2.1 2 0 0 2 2 2 1 Phage integrase family NIF PF03031.13 EDN93493.1 - 0.028 14.0 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Abhydrolase_5 PF12695.2 EDN93496.1 - 0.00035 20.3 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EDN93496.1 - 0.004 16.4 0.0 0.018 14.2 0.0 2.1 2 1 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.7 EDN93496.1 - 0.0087 14.5 0.0 0.15 10.5 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Cellulase PF00150.13 EDN93498.1 - 1.4e-20 73.6 4.3 1.9e-20 73.2 3.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_3 PF00933.16 EDN93499.1 - 1.7e-64 217.7 0.0 2.2e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN93499.1 - 2.1e-58 197.5 0.2 3.8e-58 196.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN93499.1 - 1.1e-23 82.9 0.2 2.8e-23 81.6 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.8 EDN93499.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1034 PF06280.7 EDN93499.1 - 0.037 14.4 0.6 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) WPP PF13943.1 EDN93499.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 WPP domain Glyco_hydro_31 PF01055.21 EDN93500.1 - 2.4e-114 382.6 0.6 2.9e-114 382.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN93500.1 - 9.8e-20 70.1 0.5 1.4e-18 66.4 0.0 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like MFS_1 PF07690.11 EDN93501.1 - 2e-32 112.3 27.8 2e-32 112.3 19.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Dicty_CAR PF05462.6 EDN93502.1 - 1.1e-06 27.7 8.5 1.1e-06 27.7 5.9 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EDN93502.1 - 0.0071 15.9 9.9 0.011 15.2 6.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.19 EDN93502.1 - 0.0081 15.2 4.0 0.014 14.5 2.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3_C PF11970.3 EDN93502.1 - 0.072 12.8 1.3 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term OPT PF03169.10 EDN93503.1 - 7.6e-209 695.2 35.7 9e-209 694.9 24.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S64 PF08192.6 EDN93503.1 - 1.8 6.7 3.7 3.2 5.9 2.6 1.3 1 0 0 1 1 1 0 Peptidase family S64 Inositol_P PF00459.20 EDN93505.1 - 4.4e-59 200.0 0.0 5.1e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF4580 PF15162.1 EDN93506.1 - 0.11 11.8 0.6 0.38 10.1 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4580) adh_short PF00106.20 EDN93507.1 - 1.6e-19 70.4 0.0 2.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN93507.1 - 2.5e-07 30.7 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN93507.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN93507.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Na_Ca_ex PF01699.19 EDN93510.1 - 4.3e-06 26.3 15.8 0.0002 21.0 1.1 3.1 2 2 1 3 3 3 2 Sodium/calcium exchanger protein Pirin PF02678.11 EDN93511.1 - 4.4e-23 81.1 2.0 1.6e-22 79.3 1.4 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EDN93511.1 - 5.9e-07 28.8 2.3 5.9e-06 25.6 0.3 3.1 2 1 0 2 2 2 1 Cupin domain DUF1330 PF07045.6 EDN93512.1 - 0.013 15.3 0.5 0.024 14.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) Rax2 PF12768.2 EDN93513.1 - 2e-05 23.9 0.4 5.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.5 EDN93513.1 - 0.0026 17.0 0.5 0.0026 17.0 0.3 2.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EDN93513.1 - 0.067 12.7 0.8 0.47 10.0 0.0 2.7 3 0 0 3 3 3 0 Kelch motif YajC PF02699.10 EDN93513.1 - 0.14 11.8 0.0 20 4.9 0.0 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit SieB PF14163.1 EDN93513.1 - 0.26 10.8 0.0 0.46 10.0 0.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B MIP-T3 PF10243.4 EDN93517.1 - 0.86 7.9 12.8 0.99 7.7 8.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 EDN93517.1 - 2.2 7.9 61.6 13 5.4 42.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EDN93517.1 - 5.4 7.6 77.6 1.5e+04 -5.4 53.8 2.1 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2296 PF10058.4 EDN93520.1 - 0.0069 16.1 0.5 0.0069 16.1 0.3 2.7 1 1 2 3 3 3 1 Predicted integral membrane metal-binding protein (DUF2296) C1_2 PF03107.11 EDN93520.1 - 0.081 13.0 9.7 0.13 12.4 6.8 1.4 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.19 EDN93520.1 - 0.47 10.3 8.3 0.92 9.4 5.8 1.6 1 1 0 1 1 1 0 B-box zinc finger zf-HIT PF04438.11 EDN93520.1 - 0.63 9.7 13.1 0.46 10.1 6.6 2.3 2 1 0 2 2 2 0 HIT zinc finger FYVE_2 PF02318.11 EDN93520.1 - 1 9.3 9.7 1.5 8.7 6.0 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger His_Phos_2 PF00328.17 EDN93522.1 - 3.4e-126 421.2 1.2 4.4e-126 420.8 0.8 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EDN93522.1 - 2.7e-06 26.9 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EDN93523.1 - 9e-79 263.9 0.0 1.3e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EDN93523.1 - 5.7e-24 83.0 22.5 1.7e-07 30.8 0.8 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EDN93523.1 - 0.00059 18.2 0.1 0.0023 16.2 0.0 1.9 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EDN93523.1 - 0.0017 17.1 0.3 3.4 6.3 0.0 3.3 3 1 0 4 4 4 2 Nup133 N terminal like CBM_20 PF00686.14 EDN93525.1 - 8.9e-30 102.1 0.1 2.2e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 EDN93525.1 - 4.8e-08 33.4 2.6 3.6e-05 24.1 0.0 2.7 3 0 0 3 3 3 2 Chitin binding domain IBR PF01485.16 EDN93526.1 - 8.8e-14 51.1 18.8 2.2e-07 30.6 4.8 2.6 2 0 0 2 2 2 2 IBR domain DFP PF04127.10 EDN93527.1 - 1.9e-12 47.2 0.0 3.2e-05 23.6 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Acatn PF13000.2 EDN93528.1 - 2.2e-154 515.0 26.0 8.7e-81 272.0 7.0 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 EDN93529.1 - 8.8e-25 86.7 0.0 1.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF4200 PF13863.1 EDN93529.1 - 0.043 13.7 2.1 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HTH_psq PF05225.11 EDN93532.1 - 5.3e-12 45.0 0.2 7.6e-12 44.5 0.1 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_3 PF01381.17 EDN93532.1 - 0.00016 21.4 0.1 0.00039 20.2 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 EDN93532.1 - 0.0023 17.5 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain SpoIIID PF12116.3 EDN93532.1 - 0.008 16.0 0.6 0.019 14.8 0.3 1.8 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_Tnp_Tc5 PF03221.11 EDN93532.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN93532.1 - 0.042 13.8 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.1 EDN93532.1 - 0.092 12.5 0.7 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 EDN93532.1 - 0.11 12.1 0.2 0.14 11.8 0.2 1.3 1 1 0 1 1 1 0 Transposase ChaC PF04752.7 EDN93532.1 - 0.13 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 ChaC-like protein HTH_8 PF02954.14 EDN93532.1 - 0.19 11.2 0.9 1.2 8.6 0.0 2.4 2 1 0 2 2 2 0 Bacterial regulatory protein, Fis family DDE_1 PF03184.14 EDN93533.1 - 6.2e-13 48.3 0.0 7e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CBM_5_12_2 PF14600.1 EDN93533.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Cellulose-binding domain DUF3054 PF11255.3 EDN93533.1 - 0.087 12.6 0.1 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3054) RED_N PF07808.8 EDN93534.1 - 0.0032 16.7 0.9 0.0056 15.9 0.6 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region DDE_1 PF03184.14 EDN93534.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease NAGLU PF05089.7 EDN93536.1 - 3.5e-129 430.3 4.8 3.5e-129 430.3 3.3 1.5 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EDN93536.1 - 5.7e-80 268.5 0.0 7.6e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EDN93536.1 - 6.9e-22 76.9 0.0 1.6e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain HTH_21 PF13276.1 EDN93536.1 - 0.069 13.1 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 HTH-like domain HTH_psq PF05225.11 EDN93538.1 - 1.2e-13 50.3 0.1 2.1e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN93538.1 - 1e-11 44.4 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDN93538.1 - 2e-05 24.3 0.0 9.6e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN93538.1 - 0.00074 19.2 0.5 0.0032 17.2 0.2 2.2 2 0 0 2 2 2 1 NUMOD1 domain HTH_24 PF13412.1 EDN93538.1 - 0.0031 16.8 0.4 0.0058 15.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 EDN93538.1 - 0.0031 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 EDN93538.1 - 0.0046 16.7 1.6 0.01 15.6 1.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN93538.1 - 0.0084 15.7 2.1 0.0084 15.7 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain UPF0175 PF03683.8 EDN93538.1 - 0.025 14.0 0.2 0.067 12.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_DeoR PF08220.7 EDN93538.1 - 0.027 14.0 0.1 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EDN93538.1 - 0.046 12.8 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Mga PF05043.8 EDN93538.1 - 0.049 13.9 0.4 0.18 12.1 0.1 1.9 1 1 1 2 2 2 0 Mga helix-turn-helix domain F-box PF00646.28 EDN93539.1 - 0.00044 19.8 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN93539.1 - 0.0013 18.3 0.0 0.0052 16.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like bZIP_1 PF00170.16 EDN93540.1 - 1.1e-05 25.2 8.9 3.2e-05 23.7 6.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDN93540.1 - 0.0071 16.6 2.2 0.0071 16.6 1.5 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EDN93540.1 - 0.015 15.1 7.5 0.043 13.6 5.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF1237 PF06824.6 EDN93544.1 - 9.4e-179 594.4 0.0 1.2e-178 594.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DDE_1 PF03184.14 EDN93545.1 - 1.9e-51 174.2 0.0 2.9e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93545.1 - 1.2e-12 47.1 1.6 3.1e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN93545.1 - 1.1e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN93545.1 - 3.4e-08 33.1 0.4 1.2e-07 31.3 0.0 2.2 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN93545.1 - 0.025 14.5 7.4 0.025 14.5 5.1 2.2 2 0 0 2 2 2 0 Zinc knuckle HTH_3 PF01381.17 EDN93545.1 - 0.033 14.0 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.1 EDN93545.1 - 0.044 13.1 0.2 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BLVR PF06375.6 EDN93547.1 - 0.03 14.1 1.9 0.034 13.9 1.3 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) JAB PF01398.16 EDN93548.1 - 9.8e-11 41.4 0.0 3.7e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDN93548.1 - 1.4e-08 34.8 0.0 9.9e-07 28.8 0.0 2.6 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function ADH_N PF08240.7 EDN93549.1 - 1.1e-26 92.7 2.0 2e-26 91.8 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN93549.1 - 2.4e-17 62.7 0.1 9.7e-12 44.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase TrkA_N PF02254.13 EDN93549.1 - 0.0018 18.2 0.1 0.0047 16.9 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.13 EDN93549.1 - 0.0061 16.2 0.4 0.011 15.3 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EDN93549.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EDN93549.1 - 0.031 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EDN93549.1 - 0.044 13.6 0.3 1 9.2 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDN93549.1 - 0.067 13.3 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EDN93549.1 - 0.083 13.3 0.4 0.19 12.1 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDN93549.1 - 0.098 12.0 0.4 0.22 10.8 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EDN93549.1 - 0.15 11.6 0.2 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NADH_4Fe-4S PF10589.4 EDN93549.1 - 0.33 10.1 2.7 0.73 9.0 1.9 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PX PF00787.19 EDN93550.1 - 3.3e-10 39.7 0.0 6.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EDN93550.1 - 8.4e-10 38.3 1.0 1.6e-09 37.3 0.7 1.4 1 0 0 1 1 1 1 Vps5 C terminal like CCT_2 PF09425.5 EDN93550.1 - 0.16 11.5 3.7 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Divergent CCT motif GTP_EFTU PF00009.22 EDN93551.1 - 3.6e-31 108.0 0.0 5.8e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDN93551.1 - 4.5e-25 87.3 0.0 1e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDN93551.1 - 5.5e-18 64.6 0.0 1.2e-16 60.3 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDN93551.1 - 1.7e-08 34.4 0.0 3.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Phosducin PF02114.11 EDN93555.1 - 1.5e-11 43.5 0.1 2.1e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Phosducin ANAPC15 PF15243.1 EDN93555.1 - 7.9 6.6 9.4 5 7.2 0.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Ribosomal_S27e PF01667.12 EDN93556.1 - 5.7e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EDN93556.1 - 0.0056 16.5 1.2 0.0063 16.3 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EDN93556.1 - 0.13 11.7 0.9 0.26 10.8 0.6 1.5 1 0 0 1 1 1 0 CSL zinc finger Pkinase PF00069.20 EDN93562.1 - 1.3e-38 132.6 0.0 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93562.1 - 7e-14 51.5 0.0 1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN93562.1 - 1.6e-05 24.8 0.0 0.0016 18.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDN93562.1 - 0.05 12.3 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kelch_5 PF13854.1 EDN93565.1 - 2e-35 120.1 1.8 4.9e-09 35.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EDN93565.1 - 9.9e-32 107.8 2.0 1.4e-11 44.0 0.4 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EDN93565.1 - 3.2e-31 106.8 4.4 1.6e-06 27.7 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EDN93565.1 - 6e-31 105.8 14.2 3.4e-08 33.4 0.1 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EDN93565.1 - 7.8e-31 105.3 0.3 1.9e-09 36.9 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EDN93565.1 - 4.1e-21 73.8 2.2 4.7e-08 32.4 0.1 6.7 7 0 0 7 7 7 4 Kelch motif DUF3993 PF13158.1 EDN93565.1 - 1.7 8.4 6.1 0.24 11.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Raptor_N PF14538.1 EDN93567.1 - 7.8e-64 214.1 0.0 1.5e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EDN93567.1 - 1.2e-06 28.1 4.5 0.75 9.7 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDN93567.1 - 1.3e-05 24.9 0.3 0.046 13.4 0.2 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 EDN93567.1 - 0.00067 19.3 0.2 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 EDN93567.1 - 0.092 13.0 0.1 2.5 8.4 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.17 EDN93567.1 - 0.33 11.1 4.9 6.5 7.1 0.1 4.8 6 0 0 6 6 6 0 HEAT repeat Orn_Arg_deC_N PF02784.11 EDN93570.1 - 1.1e-35 123.0 0.0 1.2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF1647 PF07801.6 EDN93570.1 - 0.033 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) DUF1408 PF07193.6 EDN93571.1 - 0.13 11.8 0.1 0.96 9.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1408) tRNA-synt_2 PF00152.15 EDN93572.1 - 1.2e-67 228.0 0.0 1.8e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN93572.1 - 5.1e-05 23.0 0.1 8.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MCM_N PF14551.1 EDN93572.1 - 0.11 12.9 0.1 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 MCM N-terminal domain NARP1 PF12569.3 EDN93572.1 - 5.2 5.7 9.0 7.7 5.1 6.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AbiH PF14253.1 EDN93573.1 - 1.8 8.1 4.9 2.5 7.6 3.4 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Ndc1_Nup PF09531.5 EDN93573.1 - 2.4 6.4 13.5 2.9 6.1 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Baculo_LEF-2 PF03041.9 EDN93573.1 - 3.1 7.4 7.8 1 8.9 0.4 2.2 1 1 1 2 2 2 0 lef-2 TFIIA PF03153.8 EDN93573.1 - 3.8 7.3 14.8 5.1 6.8 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit nec1 PF10379.4 EDN93574.1 - 0.06 12.6 0.1 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Virulence protein nec1 eIF-4B PF06273.6 EDN93574.1 - 0.12 11.0 5.0 0.14 10.8 3.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B NIPSNAP PF07978.8 EDN93576.1 - 1.1e-38 131.3 0.3 1.1e-28 99.2 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP APC_CDC26 PF10471.4 EDN93576.1 - 0.0058 17.3 1.1 0.0058 17.3 0.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 ATP-synt_J PF04911.7 EDN93577.1 - 2.4e-28 97.3 5.4 2.6e-28 97.2 3.7 1.0 1 0 0 1 1 1 1 ATP synthase j chain Aminotran_5 PF00266.14 EDN93578.1 - 4.9e-14 51.8 0.0 7.7e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDN93578.1 - 0.051 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Carn_acyltransf PF00755.15 EDN93579.1 - 2.3e-92 309.9 0.5 3.2e-92 309.5 0.3 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 EDN93579.1 - 6.6e-80 268.2 0.0 1.1e-79 267.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EDN93579.1 - 5.9e-42 143.3 0.6 3e-41 141.0 0.0 2.6 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EDN93579.1 - 3.8e-40 138.1 0.1 1.1e-39 136.7 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EDN93579.1 - 2e-35 121.2 0.0 4.6e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDN93579.1 - 6.1e-32 110.8 0.1 2e-31 109.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 EDN93579.1 - 1.7e-10 40.9 1.1 7.4e-10 38.9 0.3 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EDN93579.1 - 2.9e-08 33.3 0.0 8.1e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EDN93579.1 - 8.4e-08 31.7 0.0 2.3e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EDN93579.1 - 0.013 14.5 0.1 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 EDN93579.1 - 0.059 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EDN93579.1 - 0.088 11.6 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN93582.1 - 1.7e-34 118.8 0.0 3.4e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN93582.1 - 8.1e-24 83.7 0.0 1.6e-15 56.4 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EDN93582.1 - 2.1e-09 37.1 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN93582.1 - 2.4e-08 34.1 0.1 6.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EDN93582.1 - 0.00015 21.7 0.0 0.002 18.0 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN93582.1 - 0.025 14.2 0.0 0.65 9.6 0.0 2.6 1 1 0 1 1 1 0 KR domain Unstab_antitox PF09720.5 EDN93582.1 - 0.064 12.9 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 Putative addiction module component Rogdi_lz PF10259.4 EDN93583.1 - 8.6e-81 271.0 0.1 9.8e-81 270.8 0.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 EDN93584.1 - 2.8e-33 114.6 1.4 3.7e-33 114.1 0.9 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EDN93584.1 - 2e-19 68.9 0.3 2.9e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Alba Dynamin_N PF00350.18 EDN93586.1 - 1.2e-11 44.6 0.1 9.7e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EDN93586.1 - 7.5e-06 25.8 0.3 0.0067 16.3 0.0 3.3 3 1 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EDN93586.1 - 8.5e-05 21.7 0.1 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN93586.1 - 0.00016 21.6 0.1 0.00051 20.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EDN93586.1 - 0.00035 20.8 0.6 0.002 18.4 0.0 2.5 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.8 EDN93586.1 - 0.0014 17.5 0.0 0.0069 15.2 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Adeno_IVa2 PF02456.10 EDN93586.1 - 0.013 14.1 0.0 0.027 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein Guanylate_kin PF00625.16 EDN93586.1 - 0.02 14.3 1.3 0.45 9.9 0.0 3.0 3 0 0 3 3 3 0 Guanylate kinase AAA_29 PF13555.1 EDN93586.1 - 0.039 13.4 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN93586.1 - 0.042 13.2 0.3 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EDN93586.1 - 0.078 13.4 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PspB PF06667.7 EDN93588.1 - 0.031 14.1 0.2 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B Mis12 PF05859.7 EDN93588.1 - 0.063 13.0 0.4 0.082 12.7 0.3 1.2 1 0 0 1 1 1 0 Mis12 protein SlyX PF04102.7 EDN93588.1 - 0.17 12.2 0.9 2.5 8.5 0.1 2.2 2 0 0 2 2 2 0 SlyX DUF1154 PF06631.6 EDN93588.1 - 0.22 11.2 3.6 0.54 9.9 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) hEGF PF12661.2 EDN93589.1 - 0.093 12.8 3.0 0.2 11.8 2.1 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 EDN93589.1 - 1.3 9.2 11.9 2.3 8.4 8.2 1.4 1 0 0 1 1 1 0 EGF-like domain Phage_Coat_Gp8 PF05371.7 EDN93592.1 - 0.14 11.7 0.1 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 PCI PF01399.22 EDN93594.1 - 4.9e-21 75.0 0.0 1.7e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain EST1_DNA_bind PF10373.4 EDN93594.1 - 0.029 13.5 1.4 0.88 8.7 0.0 2.4 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain PCI_Csn8 PF10075.4 EDN93594.1 - 0.051 13.3 0.6 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Phage_Nu1 PF07471.7 EDN93594.1 - 0.056 12.9 3.0 0.057 12.8 0.4 2.2 2 1 0 2 2 2 0 Phage DNA packaging protein Nu1 CLTH PF10607.4 EDN93594.1 - 0.093 12.4 2.3 2.7 7.6 1.6 2.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain MRP-L51 PF10244.4 EDN93594.1 - 0.11 12.5 0.6 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit FSH1 PF03959.8 EDN93595.1 - 1.7e-60 204.1 0.0 2.1e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDN93595.1 - 0.0031 17.4 0.0 0.18 11.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93595.1 - 0.0039 16.9 0.0 0.0075 16.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1590 PF07629.6 EDN93596.1 - 0.054 13.0 0.9 0.068 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) PTase_Orf2 PF11468.3 EDN93598.1 - 5.2e-117 390.2 0.0 5.8e-117 390.0 0.0 1.0 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 IMS PF00817.15 EDN93600.1 - 1.2e-40 138.6 0.2 3e-40 137.4 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDN93600.1 - 7.3e-18 64.7 0.0 1.9e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EDN93600.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif GTP_EFTU PF00009.22 EDN93601.1 - 2.1e-57 193.5 0.2 3.8e-57 192.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDN93601.1 - 6.9e-34 115.5 0.1 1.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EDN93601.1 - 1.5e-29 101.9 0.0 3.2e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EDN93601.1 - 5.9e-24 83.7 0.0 1.4e-22 79.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDN93601.1 - 7e-14 51.7 0.0 2.9e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EDN93601.1 - 0.066 13.0 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Putative phosphatase (DUF442) RPEL PF02755.10 EDN93603.1 - 2.5e-29 99.7 7.4 3.2e-12 45.3 0.3 3.5 3 0 0 3 3 3 3 RPEL repeat DUF4174 PF13778.1 EDN93603.1 - 0.001 19.1 1.7 0.07 13.2 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4174) Rotamase_3 PF13616.1 EDN93603.1 - 0.047 13.9 0.9 0.3 11.3 0.1 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Pmp3 PF01679.12 EDN93606.1 - 2.4e-24 84.7 8.4 2.7e-24 84.6 5.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 EDN93606.1 - 0.16 12.0 2.7 0.19 11.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) DUF983 PF06170.7 EDN93606.1 - 0.31 11.1 2.5 0.33 11.0 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Na_Ca_ex PF01699.19 EDN93607.1 - 6.6e-29 100.2 20.1 4.4e-17 61.9 2.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.3 EDN93607.1 - 0.0046 16.1 1.3 0.0046 16.1 0.9 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3169) DUF1510 PF07423.6 EDN93607.1 - 0.16 11.2 2.4 0.3 10.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_S10 PF00450.17 EDN93608.1 - 2.7e-84 283.7 0.3 3.8e-84 283.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDN93609.1 - 2.2e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93609.1 - 0.0035 17.0 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EDN93609.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF2235 PF09994.4 EDN93610.1 - 9.5e-67 225.2 0.0 1.5e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF972 PF06156.8 EDN93610.1 - 0.14 12.4 0.9 0.4 11.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) EutA PF06277.6 EDN93610.1 - 0.35 9.4 0.2 0.5 8.9 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA SET PF00856.23 EDN93611.1 - 8.8e-07 29.3 0.2 1.8e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 SET domain GST_N_2 PF13409.1 EDN93612.1 - 7.1e-06 25.9 0.1 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN93612.1 - 0.00024 21.2 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN93612.1 - 0.00072 19.6 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain KGG PF10685.4 EDN93613.1 - 0.00083 19.2 18.6 0.027 14.4 0.5 3.4 3 1 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif DUF4355 PF14265.1 EDN93614.1 - 0.48 10.3 4.7 0.77 9.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RabGAP-TBC PF00566.13 EDN93615.1 - 1e-47 162.4 0.1 1.5e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short_C2 PF13561.1 EDN93617.1 - 4.6e-29 101.8 1.4 5.5e-29 101.6 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN93617.1 - 2.9e-27 95.6 1.7 4.1e-27 95.1 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN93617.1 - 1.7e-11 44.1 1.8 5.5e-11 42.4 1.3 1.7 1 1 0 1 1 1 1 KR domain zf-HIT PF04438.11 EDN93618.1 - 7.1e-09 35.1 10.5 1.1e-08 34.5 7.3 1.3 1 0 0 1 1 1 1 HIT zinc finger SNF2_N PF00176.18 EDN93619.1 - 1.1e-77 260.7 0.0 1.9e-77 260.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN93619.1 - 1.8e-12 46.9 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN93619.1 - 1.3e-05 25.1 0.2 0.00012 21.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EDN93619.1 - 0.0045 16.4 0.1 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 SH3_1 PF00018.23 EDN93619.1 - 0.062 12.7 0.4 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 SH3 domain HDA2-3 PF11496.3 EDN93619.1 - 0.071 11.9 3.5 0.14 10.9 0.0 2.8 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 BUD22 PF09073.5 EDN93619.1 - 1.1 8.3 33.7 0.2 10.7 18.2 2.4 2 0 0 2 2 2 0 BUD22 DDE_1 PF03184.14 EDN93620.1 - 1.2e-47 161.8 0.0 1.7e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN93620.1 - 2.9e-07 30.3 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HIM1 PF08732.5 EDN93621.1 - 2.1e-13 49.5 0.0 5.3e-13 48.2 0.0 1.6 2 0 0 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 EDN93621.1 - 1.3e-05 24.2 0.0 0.037 12.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 EDN93621.1 - 5.5e-05 23.4 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EDN93621.1 - 0.00024 20.6 0.0 0.0017 17.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDN93621.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EDN93621.1 - 0.036 12.7 0.0 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1663 PF07909.6 EDN93623.1 - 0.064 11.7 0.0 0.066 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) FAD_binding_1 PF00667.15 EDN93624.1 - 1.4e-60 204.4 0.0 2.4e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EDN93624.1 - 1.9e-12 47.7 0.0 6.1e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EDN93624.1 - 1.8e-08 34.4 0.0 5.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EDN93624.1 - 0.00024 21.0 0.0 0.00062 19.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF3500 PF12006.3 EDN93626.1 - 2.5e-28 98.9 0.0 3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.13 EDN93627.1 - 7e-52 176.0 0.0 1.1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PAF-AH_p_II PF03403.8 EDN93628.1 - 1.1e-18 66.7 0.0 1.4e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EDN93628.1 - 1e-12 48.0 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EDN93628.1 - 7.3e-05 21.7 0.1 0.00025 20.0 0.1 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDN93628.1 - 0.0017 17.2 0.7 0.2 10.4 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase DLH PF01738.13 EDN93628.1 - 0.013 14.7 0.0 0.037 13.2 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EDN93628.1 - 0.02 14.8 0.0 0.047 13.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN93628.1 - 0.053 12.7 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2812 PF11193.3 EDN93630.1 - 0.048 13.7 0.4 0.096 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) zf-C2H2 PF00096.21 EDN93632.1 - 5.9e-09 35.7 22.3 0.0001 22.3 1.1 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN93632.1 - 5e-07 29.6 21.6 0.016 15.5 1.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EDN93632.1 - 0.0025 17.9 5.0 0.65 10.2 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EDN93632.1 - 0.0082 16.3 2.0 0.0082 16.3 1.4 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EDN93632.1 - 0.07 13.4 24.9 0.36 11.1 0.5 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 EDN93632.1 - 0.19 11.8 7.6 1.9 8.6 0.3 3.2 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EDN93632.1 - 0.38 10.9 5.8 0.5 10.5 0.8 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EDN93632.1 - 1.2 9.3 12.2 4.8 7.3 4.8 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EDN93632.1 - 1.3 8.7 6.9 8 6.2 0.8 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_hydro_12 PF01670.11 EDN93633.1 - 9.4e-15 54.7 1.4 5.3e-14 52.2 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Ank_2 PF12796.2 EDN93634.1 - 7.6e-21 74.2 2.7 5.6e-12 45.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN93634.1 - 1.8e-10 40.0 1.2 3.4e-05 23.4 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDN93634.1 - 2.7e-10 40.1 2.2 3.7e-05 23.8 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN93634.1 - 2.8e-09 37.2 0.6 0.00029 21.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN93634.1 - 1.1e-07 31.3 0.7 0.0023 18.0 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EDN93635.1 - 0.01 16.1 0.0 1.2 9.5 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.25 EDN93635.1 - 0.029 14.1 1.3 0.37 10.7 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeat p31comet PF06581.7 EDN93636.1 - 0.072 11.9 0.3 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding SLD3 PF08639.5 EDN93637.1 - 0.067 11.8 0.1 0.078 11.6 0.0 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Med7 PF05983.6 EDN93638.1 - 3.6e-20 72.3 0.5 4.6e-20 72.0 0.3 1.1 1 0 0 1 1 1 1 MED7 protein HTH_38 PF13936.1 EDN93638.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PAP2 PF01569.16 EDN93639.1 - 2.9e-24 85.1 0.3 2.9e-24 85.1 0.2 2.0 2 1 0 2 2 2 1 PAP2 superfamily Frag1 PF10277.4 EDN93639.1 - 0.1 12.0 3.2 0.1 12.0 1.2 1.7 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family FtsX PF02687.16 EDN93639.1 - 0.17 11.6 3.5 2.4 7.9 0.0 2.8 2 1 1 3 3 3 0 FtsX-like permease family DivIC PF04977.10 EDN93640.1 - 0.017 14.5 1.0 0.017 14.5 0.7 4.2 4 0 0 4 4 4 0 Septum formation initiator NPV_P10 PF05531.7 EDN93640.1 - 0.63 10.3 11.3 2.9 8.2 0.6 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EDN93640.1 - 6.4 7.0 11.2 29 4.8 3.3 3.1 2 1 0 2 2 2 0 Syntaxin Hemerythrin PF01814.18 EDN93641.1 - 1.1e-15 57.9 1.0 1.5e-15 57.4 0.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Catalase PF00199.14 EDN93642.1 - 3e-147 490.3 0.8 3.7e-147 490.0 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN93642.1 - 1.2e-11 44.2 0.1 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive TPR_7 PF13176.1 EDN93642.1 - 0.035 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EDN93644.1 - 5.2e-37 127.3 0.0 4.7e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93644.1 - 2e-25 89.3 0.0 4e-25 88.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3552 PF12072.3 EDN93644.1 - 0.0033 16.6 9.7 0.0071 15.5 6.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) APH PF01636.18 EDN93644.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family ADIP PF11559.3 EDN93644.1 - 0.23 11.3 17.3 0.1 12.4 8.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EDN93644.1 - 0.28 10.7 4.6 0.54 9.8 3.2 1.4 1 0 0 1 1 1 0 IncA protein Glyoxalase PF00903.20 EDN93648.1 - 3.4e-27 94.9 0.1 1.6e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDN93648.1 - 1.9e-21 76.6 0.0 3.1e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EDN93648.1 - 6.8e-14 51.8 0.1 2.1e-07 30.9 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDN93648.1 - 1.8e-05 24.7 0.0 0.055 13.3 0.0 2.7 1 1 2 3 3 3 3 Glyoxalase-like domain DUF4105 PF13387.1 EDN93648.1 - 0.063 12.4 0.1 1.5 7.9 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4105) Imm1 PF14430.1 EDN93648.1 - 0.1 12.7 0.0 11 6.1 0.0 2.5 3 0 0 3 3 3 0 Immunity protein Imm1 2-Hacid_dh PF00389.25 EDN93649.1 - 3.9e-24 84.6 0.0 4.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EDN93649.1 - 6.3e-11 41.7 0.7 1.1e-10 40.9 0.5 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HSP70 PF00012.15 EDN93650.1 - 0.0013 16.7 0.2 0.0029 15.5 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein DUF1679 PF07914.6 EDN93653.1 - 0.023 13.3 0.4 0.034 12.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mito_fiss_reg PF05308.6 EDN93653.1 - 1.1 8.6 3.2 1.8 7.9 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator COX4_pro_2 PF07835.7 EDN93654.1 - 0.014 15.3 0.7 0.028 14.4 0.1 1.8 1 1 1 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Yip1 PF04893.12 EDN93654.1 - 0.055 12.9 4.7 0.084 12.3 3.2 1.2 1 0 0 1 1 1 0 Yip1 domain eIF-3c_N PF05470.7 EDN93654.1 - 0.092 10.8 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1426 PF07234.6 EDN93654.1 - 5.1 6.8 6.4 2.6 7.7 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1426) zf-DHHC PF01529.15 EDN93654.1 - 5.4 6.3 7.5 10 5.4 5.2 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_16 PF13191.1 EDN93656.1 - 3.6e-06 27.1 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EDN93656.1 - 3.9e-05 23.3 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EDN93656.1 - 4e-05 23.7 0.0 0.00022 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDN93656.1 - 0.0055 16.1 0.0 0.12 11.8 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EDN93656.1 - 0.0057 17.4 1.7 0.62 10.8 0.0 4.0 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 EDN93656.1 - 0.048 13.8 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EDN93656.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SRF-TF PF00319.13 EDN93659.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) PS_Dcarbxylase PF02666.10 EDN93659.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase zf-RVT PF13966.1 EDN93660.1 - 0.0089 16.3 0.2 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase MATH PF00917.21 EDN93660.1 - 0.034 14.3 0.4 0.13 12.4 0.1 2.0 2 1 0 2 2 2 0 MATH domain RVT_2 PF07727.9 EDN93661.1 - 3e-50 170.4 0.0 3.5e-49 166.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN93661.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN93661.1 - 0.00017 21.1 0.7 0.0005 19.6 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN93661.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DDE_1 PF03184.14 EDN93663.1 - 9.6e-51 171.9 0.0 6.5e-50 169.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN93663.1 - 1.4e-13 50.8 0.0 3.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93663.1 - 4.6e-13 48.5 3.1 2.5e-12 46.1 0.3 2.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN93663.1 - 3.8e-11 42.6 0.2 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN93663.1 - 0.0079 16.2 0.1 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 EDN93664.1 - 1e-15 57.2 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EDN93664.1 - 5.5e-10 39.1 0.2 3.2e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EDN93664.1 - 5.9e-09 36.3 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EDN93664.1 - 1.2e-06 28.1 2.6 2.2e-06 27.2 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 EDN93664.1 - 1.3e-05 24.6 0.1 0.00023 20.6 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EDN93664.1 - 0.00016 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDN93664.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_5 PF14787.1 EDN93664.1 - 0.047 13.1 8.1 0.02 14.3 3.7 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3443 PF11925.3 EDN93664.1 - 0.21 10.2 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) DUF21 PF01595.15 EDN93668.1 - 1.8e-32 112.1 0.0 3.5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EDN93668.1 - 2.8e-07 30.1 0.1 0.0059 16.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain Abhydrolase_6 PF12697.2 EDN93670.1 - 1e-25 90.9 0.0 1.3e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN93670.1 - 5.1e-18 65.4 0.0 6.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN93670.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN93670.1 - 0.00029 20.6 0.0 0.00091 19.0 0.0 1.8 1 1 1 2 2 2 1 Putative lysophospholipase Minor_capsid_3 PF12691.2 EDN93670.1 - 0.12 12.0 0.6 8.5 6.0 0.2 2.2 1 1 1 2 2 2 0 Minor capsid protein from bacteriophage p450 PF00067.17 EDN93671.1 - 6.1e-50 170.0 0.0 7.9e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad4 PF03835.10 EDN93673.1 - 2.1e-31 108.2 0.0 4.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EDN93673.1 - 5e-25 87.0 0.1 1e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDN93673.1 - 4.2e-19 67.8 0.0 9.2e-19 66.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDN93673.1 - 4e-16 59.0 0.1 1.1e-15 57.6 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDN93673.1 - 0.022 14.9 0.0 0.074 13.2 0.0 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily Ank_2 PF12796.2 EDN93674.1 - 2.4e-24 85.4 0.1 3.9e-08 33.5 0.0 3.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN93674.1 - 2.9e-15 55.1 0.8 0.0065 16.2 0.1 5.9 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EDN93674.1 - 3.5e-15 56.0 0.3 8.2e-06 26.1 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN93674.1 - 3.3e-11 42.2 0.8 0.12 12.6 0.0 5.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EDN93674.1 - 9e-07 28.9 0.3 0.044 14.0 0.0 5.3 3 3 3 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.2 EDN93674.1 - 0.011 15.4 0.6 0.025 14.3 0.4 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EDN93674.1 - 0.054 13.1 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain PPO1_DWL PF12142.3 EDN93676.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Ank PF00023.25 EDN93677.1 - 1.8e-07 30.6 0.5 4.8e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDN93677.1 - 3.2e-07 30.6 0.0 5.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN93677.1 - 6.3e-06 25.9 0.8 0.0017 18.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EDN93677.1 - 2.5e-05 24.6 0.2 0.017 15.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN93677.1 - 0.0057 16.8 0.2 0.16 12.2 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Pirin PF02678.11 EDN93677.1 - 0.02 14.7 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Pirin Ank PF00023.25 EDN93678.1 - 1.5e-07 30.8 0.0 0.016 15.0 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDN93678.1 - 1.6e-06 28.3 0.3 1.7e-05 25.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN93678.1 - 0.00012 22.5 0.0 0.32 11.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN93678.1 - 0.004 17.2 0.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EDN93678.1 - 0.034 14.3 0.0 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CN_hydrolase PF00795.17 EDN93679.1 - 6.6e-25 87.5 0.0 1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cellulase PF00150.13 EDN93680.1 - 1.7e-10 40.5 2.0 2.9e-10 39.8 1.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EDN93680.1 - 0.014 15.7 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Transket_pyr PF02779.19 EDN93681.1 - 2e-40 138.1 0.0 2.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN93681.1 - 8.2e-31 106.5 0.1 1.8e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain RCC1 PF00415.13 EDN93683.1 - 9.3e-26 89.8 0.1 7.4e-08 32.4 0.0 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EDN93683.1 - 8.2e-14 51.5 0.0 2.4e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EDN93683.1 - 3.6e-10 40.0 0.0 7.9e-09 35.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EDN93683.1 - 4.8e-09 35.5 2.8 2.3e-07 30.2 0.5 3.5 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EDN93683.1 - 7.5e-06 25.7 0.1 0.029 14.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDN93683.1 - 0.00063 20.0 0.0 0.0025 18.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN93683.1 - 0.0015 18.7 0.0 2.5 8.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EDN93683.1 - 0.018 14.8 0.0 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF1160 PF06648.6 EDN93683.1 - 0.17 11.6 0.2 0.39 10.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) SET PF00856.23 EDN93684.1 - 2.1e-08 34.6 0.0 8.1e-07 29.4 0.0 2.6 1 1 0 1 1 1 1 SET domain Glycoprotein_B PF00606.13 EDN93685.1 - 0.00057 18.0 3.8 0.00064 17.8 2.6 1.0 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Baculo_PEP_C PF04513.7 EDN93685.1 - 0.016 15.0 3.6 0.04 13.7 2.5 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3318 PF11780.3 EDN93685.1 - 0.073 12.6 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) P12 PF12669.2 EDN93685.1 - 0.29 11.3 1.3 0.87 9.8 0.0 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF1035 PF06281.7 EDN93685.1 - 0.37 10.6 5.4 1.5 8.6 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1035) SPC12 PF06645.8 EDN93685.1 - 1.3 8.8 5.5 0.38 10.5 1.3 1.8 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Copper-fist PF00649.13 EDN93687.1 - 1.2e-21 75.5 3.0 1.2e-21 75.5 2.1 2.6 1 1 1 2 2 2 2 Copper fist DNA binding domain Zn_clus PF00172.13 EDN93688.1 - 1.2e-10 41.1 11.3 1.8e-10 40.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN93688.1 - 2.5e-07 29.8 0.7 1.1e-06 27.7 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_M14 PF00246.19 EDN93689.1 - 1.2e-39 136.6 0.1 1.6e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_3 PF07859.8 EDN93690.1 - 4.5e-38 130.9 0.0 7.4e-30 104.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN93690.1 - 1.8e-15 56.4 0.0 3.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDN93690.1 - 0.0017 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDN93690.1 - 0.0031 16.3 0.1 0.036 12.7 0.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family WGG PF10273.4 EDN93691.1 - 6.5e-29 99.8 0.2 9.8e-29 99.2 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 S-antigen PF05756.6 EDN93691.1 - 0.24 11.4 1.6 0.37 10.7 1.1 1.3 1 0 0 1 1 1 0 S-antigen protein BSD PF03909.12 EDN93692.1 - 1.3e-13 50.5 0.9 3.1e-13 49.2 0.6 1.7 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EDN93692.1 - 0.0044 16.7 4.5 0.0099 15.6 3.1 1.6 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAP1 PF08601.5 EDN93694.1 - 9.6e-57 193.2 46.3 9.6e-57 193.2 32.1 4.4 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EDN93694.1 - 2e-08 34.0 8.5 4.1e-08 33.0 5.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN93694.1 - 0.0046 16.7 10.2 0.017 14.9 7.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 EDN93694.1 - 0.012 16.0 0.8 0.012 16.0 0.5 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 EDN93694.1 - 0.19 12.0 8.6 0.41 10.9 5.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor GAS PF13851.1 EDN93694.1 - 0.33 10.1 7.7 0.36 10.0 3.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG7 PF10191.4 EDN93694.1 - 0.42 8.4 1.7 0.65 7.8 1.2 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) IncA PF04156.9 EDN93694.1 - 1.5 8.4 3.6 3 7.4 2.5 1.4 1 0 0 1 1 1 0 IncA protein Chromate_transp PF02417.10 EDN93697.1 - 0.077 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromate transporter Pkinase PF00069.20 EDN93699.1 - 8.7e-71 238.1 0.0 1.6e-70 237.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93699.1 - 1.7e-30 105.9 0.0 3.2e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN93699.1 - 3e-05 23.1 0.0 0.39 9.6 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EDN93699.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mre11_DNA_bind PF04152.9 EDN93700.1 - 3.1e-52 176.9 5.3 5.2e-51 172.9 0.6 2.3 2 0 0 2 2 2 2 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EDN93700.1 - 4.7e-26 91.4 2.4 6.7e-26 90.9 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN93700.1 - 1.2e-05 25.1 2.1 3.2e-05 23.8 1.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FATC PF02260.15 EDN93700.1 - 0.72 9.3 2.0 5.7 6.4 0.1 2.4 2 0 0 2 2 2 0 FATC domain Ribosomal_S19 PF00203.16 EDN93701.1 - 3.1e-23 81.1 0.1 5.4e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EDN93702.1 - 3.9e-26 90.6 0.3 5.8e-26 90.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EDN93702.1 - 0.00094 19.5 0.4 0.0016 18.8 0.3 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 OB_NTP_bind PF07717.11 EDN93703.1 - 9.8e-27 93.0 0.1 2.3e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN93703.1 - 7.8e-24 83.6 0.3 2.7e-23 81.9 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN93703.1 - 1.4e-11 44.0 0.0 4.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN93703.1 - 1.6e-06 27.7 0.2 4.3e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN93703.1 - 7.3e-06 26.1 0.1 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDN93703.1 - 0.00066 19.1 0.1 0.0024 17.3 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EDN93703.1 - 0.0018 18.1 0.0 0.96 9.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDN93703.1 - 0.012 15.4 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SE PF00437.15 EDN93703.1 - 0.022 13.6 0.0 0.049 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EDN93703.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDN93703.1 - 0.063 12.5 0.1 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Glyco_transf_25 PF01755.12 EDN93709.1 - 3e-05 23.7 0.0 1.5 8.3 0.0 3.1 2 1 1 3 3 3 3 Glycosyltransferase family 25 (LPS biosynthesis protein) DSBA PF01323.15 EDN93712.1 - 2.5e-12 46.7 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DDHD PF02862.12 EDN93713.1 - 9.2e-42 143.3 0.0 9.2e-42 143.3 0.0 5.6 2 2 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 EDN93713.1 - 0.068 13.0 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EDN93713.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Dehydrin PF00257.14 EDN93714.1 - 0.008 16.5 6.0 0.032 14.5 4.2 2.1 1 1 0 1 1 1 1 Dehydrin DNA_pol_B_3 PF08408.5 EDN93714.1 - 0.034 14.0 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase family B viral insert FAD_binding_3 PF01494.14 EDN93715.1 - 1.6e-75 254.4 0.0 2.1e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDN93715.1 - 9.3e-43 145.7 0.1 1.5e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Lycopene_cycl PF05834.7 EDN93715.1 - 0.0021 17.0 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EDN93715.1 - 0.0022 18.3 0.1 0.018 15.4 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EDN93715.1 - 0.0079 15.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EDN93715.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN93715.1 - 0.017 15.0 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN93715.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 EDN93715.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.19 EDN93715.1 - 0.055 12.3 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDN93715.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDI PF00996.13 EDN93715.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.16 EDN93715.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Peptidase_C48 PF02902.14 EDN93716.1 - 3.4e-19 69.3 0.0 1.1e-18 67.6 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BCAS2 PF05700.6 EDN93716.1 - 0.097 12.1 7.0 0.037 13.4 1.7 2.6 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3337 PF11816.3 EDN93717.1 - 1.6e-83 280.8 0.0 8.6e-80 268.6 0.7 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EDN93717.1 - 1.4e-23 81.7 12.7 9.1e-08 31.7 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Cupin_8 PF13621.1 EDN93718.1 - 9.7e-39 133.3 0.0 1.4e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Kelch_5 PF13854.1 EDN93718.1 - 8.4e-10 38.3 0.4 0.0013 18.6 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EDN93718.1 - 2e-08 33.8 10.8 0.01 15.6 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EDN93718.1 - 3.8e-08 32.7 1.2 0.31 10.6 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Cupin_4 PF08007.7 EDN93718.1 - 1.7e-06 27.5 0.0 3.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.1 EDN93718.1 - 7e-05 22.8 4.1 1.3 9.3 0.1 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EDN93718.1 - 0.001 18.7 3.5 0.18 11.6 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 EDN93718.1 - 0.0034 17.4 11.0 0.0048 17.0 0.3 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain RCC_reductase PF06405.6 EDN93718.1 - 0.039 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) WD40 PF00400.27 EDN93719.1 - 9.5e-07 28.4 4.6 0.0013 18.5 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat CPSF_A PF03178.10 EDN93719.1 - 0.018 14.1 0.1 4.3 6.3 0.0 2.9 2 2 0 2 2 2 0 CPSF A subunit region zf-C2H2 PF00096.21 EDN93721.1 - 3.8e-13 48.9 17.5 0.00043 20.4 1.7 4.1 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN93721.1 - 1.5e-09 37.4 14.4 0.0029 17.8 0.7 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN93721.1 - 2.7e-06 27.3 19.8 0.00014 21.9 1.1 4.3 4 1 1 5 5 5 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EDN93721.1 - 0.0053 16.9 11.2 0.0094 16.1 0.4 4.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EDN93721.1 - 0.57 10.4 11.9 0.41 10.8 1.3 3.7 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EDN93721.1 - 3.4 8.1 11.8 1.2 9.5 4.5 2.6 2 1 1 3 3 3 0 TRAF-type zinc finger Mito_carr PF00153.22 EDN93727.1 - 4.5e-47 157.6 9.9 2.5e-18 65.5 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 EDN93727.1 - 0.21 11.7 0.3 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family ATP_bind_3 PF01171.15 EDN93728.1 - 7.5e-34 116.8 0.0 3.8e-15 55.8 0.0 3.2 2 1 1 3 3 3 3 PP-loop family DUF2893 PF11459.3 EDN93728.1 - 0.0069 16.1 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknwon function (DUF2893) Asn_synthase PF00733.16 EDN93728.1 - 0.042 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase Plasmodium_Vir PF05795.6 EDN93729.1 - 0.0032 16.7 0.3 0.0048 16.1 0.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Rax2 PF12768.2 EDN93729.1 - 0.0044 16.2 0.3 0.0065 15.7 0.1 1.3 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Rifin_STEVOR PF02009.11 EDN93729.1 - 0.0074 15.9 0.0 0.0096 15.6 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family DUF1517 PF07466.6 EDN93729.1 - 0.36 9.7 5.0 0.53 9.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Macoilin PF09726.4 EDN93729.1 - 5.3 5.1 6.0 5.4 5.1 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 7kD_coat PF02495.12 EDN93731.1 - 0.19 11.2 0.5 0.29 10.6 0.4 1.3 1 0 0 1 1 1 0 7kD viral coat protein DSPc PF00782.15 EDN93732.1 - 6.1e-25 87.3 0.0 3.3e-21 75.2 0.0 2.2 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN93732.1 - 2.3e-06 27.1 0.1 2.4e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EDN93732.1 - 0.075 12.4 0.0 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) eRF1_1 PF03463.10 EDN93735.1 - 1.8e-47 160.2 0.0 3.3e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EDN93735.1 - 3.5e-23 82.4 0.0 5.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDN93735.1 - 4.7e-21 75.1 0.0 8.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 EDN93736.1 - 9.3e-46 155.9 0.0 1.3e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_pol_Rpb1_5 PF04998.12 EDN93737.1 - 3.8e-87 292.0 0.0 1e-86 290.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDN93737.1 - 5.3e-65 218.4 0.1 1e-64 217.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDN93737.1 - 9.2e-33 113.1 0.0 3e-32 111.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EDN93737.1 - 2.1e-32 112.6 0.5 3.2e-23 82.5 0.0 3.0 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EDN93737.1 - 1.3e-16 60.3 0.0 5.6e-16 58.2 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 EDN93738.1 - 7.1e-71 238.1 4.9 1.1e-70 237.4 3.4 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EDN93738.1 - 1.5e-39 134.5 1.1 1.5e-39 134.5 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF1227 PF06777.6 EDN93739.1 - 3e-59 198.9 0.6 6.2e-59 197.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EDN93739.1 - 4.9e-52 175.8 0.2 7.8e-52 175.1 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EDN93739.1 - 6.8e-37 126.9 0.6 1.7e-32 112.6 0.1 2.8 1 1 1 2 2 2 2 Helicase C-terminal domain DEAD PF00270.24 EDN93739.1 - 0.00036 20.0 0.1 0.084 12.3 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EDN93739.1 - 0.00068 18.5 0.0 0.0038 16.0 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EDN93739.1 - 0.0092 16.1 0.2 1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EDN93739.1 - 0.02 14.7 0.2 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN93739.1 - 0.098 11.8 0.1 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF4528 PF15031.1 EDN93740.1 - 0.11 12.2 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Histone PF00125.19 EDN93741.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDN93741.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN93741.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDN93741.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EDN93742.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDN93742.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDN93742.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN93742.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDN93742.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EDN93742.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GTP_cyclohydroI PF01227.17 EDN93743.1 - 1.1e-73 246.3 0.5 1.5e-73 245.8 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EDN93743.1 - 0.0037 17.1 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein Thymidylate_kin PF02223.12 EDN93744.1 - 4.7e-42 143.4 0.0 5.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 EDN93744.1 - 0.0039 18.0 0.0 0.0079 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EDN93744.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase AAA_14 PF13173.1 EDN93744.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EDN93744.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.1 EDN93744.1 - 0.098 12.9 0.0 0.34 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF1546 PF07571.8 EDN93745.1 - 3.4e-29 100.7 0.0 2.5e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EDN93745.1 - 8.1e-21 73.7 0.0 1.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EDN93745.1 - 0.039 14.0 0.1 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 COesterase PF00135.23 EDN93746.1 - 2.7e-77 260.6 0.2 7.6e-77 259.2 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN93746.1 - 4.1e-08 33.0 0.2 3.2e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_1 PF00667.15 EDN93747.1 - 5.7e-46 156.7 0.0 4.6e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EDN93747.1 - 6.3e-11 42.8 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 EDN93748.1 - 5.4e-15 55.5 0.1 7.4e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Nitroreductase family COesterase PF00135.23 EDN93752.1 - 0.047 12.3 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF4066 PF13278.1 EDN93753.1 - 4.6e-22 78.0 0.0 4.5e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EDN93753.1 - 1.4e-09 37.6 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.14 EDN93753.1 - 0.041 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Mito_carr PF00153.22 EDN93754.1 - 1.3e-46 156.2 6.8 2e-16 59.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein E1_dh PF00676.15 EDN93759.1 - 3.1e-119 397.1 0.4 3.8e-119 396.8 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDN93759.1 - 5.1e-05 22.3 0.0 9.5e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 EDN93760.1 - 1.5e-52 173.6 16.5 5.2e-10 38.8 0.2 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EDN93760.1 - 5.6e-11 41.2 6.7 0.00061 18.0 0.5 4.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EDN93760.1 - 2.6e-10 39.8 1.2 4.9e-10 38.9 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN93760.1 - 0.00012 21.5 2.2 0.00025 20.5 1.5 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EDN93760.1 - 0.0033 16.2 0.8 0.18 10.5 0.0 3.3 2 1 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.1 EDN93760.1 - 0.0099 15.3 5.4 0.061 12.7 0.6 3.2 1 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 EDN93760.1 - 0.017 15.4 0.5 33 4.9 0.0 4.7 6 1 0 6 6 6 0 PQQ-like domain Zip PF02535.17 EDN93761.1 - 8.3e-40 136.7 10.4 3.6e-38 131.3 7.2 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3620 PF12281.3 EDN93761.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) PDR_assoc PF08370.6 EDN93761.1 - 0.097 12.1 0.1 0.097 12.1 0.1 2.1 2 0 0 2 2 2 0 Plant PDR ABC transporter associated HlyIII PF03006.15 EDN93761.1 - 0.9 8.9 9.6 0.86 8.9 1.4 2.3 2 0 0 2 2 2 0 Haemolysin-III related Hat1_N PF10394.4 EDN93762.1 - 4.1e-38 130.9 0.0 8.3e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus P5CR_dimer PF14748.1 EDN93763.1 - 2.5e-26 91.7 1.2 4.4e-26 90.9 0.8 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDN93763.1 - 2.2e-05 24.7 0.0 6.5e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EDN93763.1 - 0.053 12.4 0.1 0.16 10.7 0.0 1.7 1 1 1 2 2 2 0 Prephenate dehydrogenase RVT_1 PF00078.22 EDN93765.1 - 1.3e-37 129.2 0.0 2.2e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN93765.1 - 7.8e-10 39.2 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 RNase H AAA PF00004.24 EDN93767.1 - 3.1e-41 140.6 0.6 5.2e-14 52.5 0.0 5.6 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EDN93767.1 - 7.8e-39 133.1 0.2 5e-38 130.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EDN93767.1 - 3.2e-29 102.1 22.5 1.3e-24 87.1 0.0 6.9 6 0 0 6 6 6 2 AAA domain AAA_19 PF13245.1 EDN93767.1 - 2.7e-21 75.0 1.1 8.3e-06 25.4 0.0 5.3 5 0 0 5 5 5 4 Part of AAA domain AAA_5 PF07728.9 EDN93767.1 - 1.8e-12 47.1 1.6 0.022 14.4 0.0 5.3 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN93767.1 - 5.3e-11 43.3 20.4 0.02 15.7 0.0 6.5 6 0 0 6 6 4 4 AAA domain AAA_30 PF13604.1 EDN93767.1 - 9.8e-11 41.6 23.1 0.0055 16.3 0.0 8.5 7 3 1 8 8 7 4 AAA domain Mg_chelatase PF01078.16 EDN93767.1 - 2.5e-10 39.8 0.3 0.53 9.4 0.0 5.2 5 0 0 5 5 5 4 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EDN93767.1 - 8.6e-10 38.5 0.6 0.16 11.4 0.0 5.9 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDN93767.1 - 7.8e-09 35.7 19.2 0.11 12.6 0.0 8.3 6 3 0 6 6 6 3 AAA domain IstB_IS21 PF01695.12 EDN93767.1 - 5.7e-08 32.3 0.1 2.2 7.6 0.0 5.1 4 0 0 4 4 4 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EDN93767.1 - 3.7e-07 30.2 0.1 1.2 9.3 0.0 5.0 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.1 EDN93767.1 - 6.2e-06 26.3 20.5 0.7 9.8 0.1 6.2 6 0 0 6 6 6 4 AAA ATPase domain AAA_14 PF13173.1 EDN93767.1 - 9.9e-06 25.4 0.1 0.087 12.7 0.0 4.8 5 0 0 5 5 4 1 AAA domain Torsin PF06309.6 EDN93767.1 - 4.6e-05 23.2 0.0 0.52 10.1 0.0 4.5 4 0 0 4 4 4 1 Torsin AAA_25 PF13481.1 EDN93767.1 - 0.00026 20.4 1.7 10 5.4 0.0 4.8 4 0 0 4 4 4 0 AAA domain PhoH PF02562.11 EDN93767.1 - 0.00044 19.5 0.7 1.1 8.4 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein AAA_33 PF13671.1 EDN93767.1 - 0.00075 19.3 20.9 0.67 9.8 0.0 6.0 5 1 0 5 5 4 3 AAA domain AAA_24 PF13479.1 EDN93767.1 - 0.0019 17.8 10.8 2.5 7.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain ResIII PF04851.10 EDN93767.1 - 0.0064 16.3 9.0 0.092 12.5 0.0 5.4 6 1 1 7 7 5 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EDN93767.1 - 0.046 12.6 0.0 0.046 12.6 0.0 6.6 8 2 0 8 8 7 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EDN93767.1 - 0.091 12.4 4.4 24 4.5 0.0 4.6 4 0 0 4 4 4 0 NACHT domain MobB PF03205.9 EDN93767.1 - 0.16 11.6 1.9 55 3.4 0.0 3.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EDN93767.1 - 0.37 10.4 8.2 18 4.9 0.0 4.3 4 0 0 4 4 3 0 NTPase AAA_18 PF13238.1 EDN93767.1 - 1.2 9.4 35.1 0.69 10.2 0.0 6.8 7 0 0 7 7 5 0 AAA domain ADK PF00406.17 EDN93767.1 - 1.8 8.4 9.4 13 5.6 0.0 4.3 5 0 0 5 5 3 0 Adenylate kinase Sugar_tr PF00083.19 EDN93769.1 - 5e-11 41.8 1.3 6.3e-11 41.5 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93769.1 - 2.6e-10 39.5 4.6 3.3e-10 39.2 3.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN93769.1 - 0.0031 15.9 1.8 0.0047 15.3 1.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 EDN93769.1 - 0.17 10.0 1.8 0.21 9.7 1.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EDN93771.1 - 5.1e-75 252.7 0.0 6.4e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELMO_CED12 PF04727.8 EDN93771.1 - 0.0095 15.4 0.1 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family MRP-S26 PF14943.1 EDN93774.1 - 0.024 14.1 0.2 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-LSD1 PF06943.7 EDN93775.1 - 0.15 11.7 1.1 0.27 10.8 0.8 1.4 1 0 0 1 1 1 0 LSD1 zinc finger DUF566 PF04484.7 EDN93790.1 - 0.002 17.7 2.2 0.002 17.7 1.5 3.0 2 1 1 3 3 3 1 Family of unknown function (DUF566) DUF559 PF04480.7 EDN93793.1 - 0.051 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF559) SYF2 PF08231.7 EDN93794.1 - 3.3e-27 95.4 2.3 3.3e-27 95.4 1.6 2.1 2 0 0 2 2 2 1 SYF2 splicing factor NAD_binding_10 PF13460.1 EDN93795.1 - 6.6e-13 49.0 0.0 1.5e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN93795.1 - 2.4e-07 30.4 0.0 5.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN93795.1 - 3.4e-05 22.7 0.0 0.00017 20.4 0.0 2.0 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDN93795.1 - 0.0014 17.5 0.0 0.053 12.4 0.0 2.6 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.20 EDN93795.1 - 0.0048 16.8 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EDN93795.1 - 0.035 12.9 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain YEATS PF03366.11 EDN93796.1 - 5.8e-31 106.0 0.4 9e-31 105.4 0.3 1.3 1 0 0 1 1 1 1 YEATS family DUF641 PF04859.7 EDN93796.1 - 0.053 13.2 0.6 0.091 12.5 0.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2404 PF10296.4 EDN93797.1 - 6.7e-05 22.9 0.0 0.00044 20.3 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 EDN93798.1 - 5.6e-68 229.2 0.1 6.5e-68 229.0 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF2713 PF10897.3 EDN93798.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) zf-met PF12874.2 EDN93799.1 - 0.19 11.9 2.4 12 6.3 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDN93799.1 - 0.56 10.6 28.9 0.084 13.2 1.4 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN93799.1 - 0.93 9.7 3.9 21 5.4 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Nucleoside_tran PF01733.13 EDN93800.1 - 6e-42 143.8 4.7 2.1e-40 138.8 3.2 2.5 1 1 0 1 1 1 1 Nucleoside transporter Clc-like PF07062.7 EDN93800.1 - 6.5 5.9 9.0 0.78 8.9 2.4 2.2 2 1 0 2 2 2 0 Clc-like SNARE PF05739.14 EDN93802.1 - 7.4e-18 64.0 2.5 7.4e-18 64.0 1.7 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EDN93802.1 - 2.7e-12 46.7 1.7 2.7e-12 46.7 1.2 2.2 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EDN93802.1 - 0.0046 16.5 9.2 0.015 14.8 0.6 2.5 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2019 PF09450.5 EDN93802.1 - 0.06 13.2 0.4 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DNA_repr_REX1B PF14966.1 EDN93802.1 - 1.5 9.2 6.6 0.5 10.7 0.1 2.9 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.27 EDN93803.1 - 2.4e-41 135.8 11.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDN93803.1 - 1e-36 124.8 5.0 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EDN93803.1 - 4.9e-35 118.9 10.8 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EDN93803.1 - 1.4e-30 102.3 7.0 2.8e-09 36.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDN93803.1 - 8.6e-27 91.2 8.7 4.5e-07 28.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EDN93803.1 - 3.5e-15 55.6 0.2 6.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDN93803.1 - 1.4e-09 37.6 1.5 0.00059 19.5 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDN93803.1 - 6e-09 35.9 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EDN93803.1 - 2.3e-08 33.5 0.0 0.015 14.8 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EDN93803.1 - 8.1e-07 28.9 2.0 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EDN93803.1 - 7.5e-05 22.4 0.3 0.16 11.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EDN93803.1 - 0.00016 21.2 0.2 0.053 13.0 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EDN93803.1 - 0.0026 17.3 0.1 0.13 11.7 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EDN93803.1 - 0.0041 17.1 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF3349 PF11829.3 EDN93803.1 - 0.021 15.2 0.3 9.4 6.7 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) YqeY PF09424.5 EDN93803.1 - 0.096 12.5 0.7 0.51 10.1 0.2 2.0 1 1 0 2 2 2 0 Yqey-like protein EF-hand_10 PF14788.1 EDN93803.1 - 0.1 12.3 2.6 0.83 9.3 0.1 3.3 2 1 2 4 4 4 0 EF hand PB1 PF00564.19 EDN93803.1 - 0.5 10.0 2.8 35 4.1 0.0 3.2 2 1 1 3 3 3 0 PB1 domain RloB PF13707.1 EDN93803.1 - 0.5 9.9 2.3 0.91 9.1 1.5 1.8 1 1 0 1 1 1 0 RloB-like protein Glyco_hydro_47 PF01532.15 EDN93804.1 - 9.6e-165 548.6 0.0 3.3e-164 546.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3635 PF12330.3 EDN93805.1 - 4.5e-06 26.6 0.0 8.7e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 EDN93806.1 - 5.3e-112 373.8 3.9 6.1e-112 373.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DRY_EERY PF09750.4 EDN93806.1 - 9.2 6.3 9.5 40 4.3 6.3 2.1 2 0 0 2 2 2 0 Alternative splicing regulator Amidoligase_2 PF12224.3 EDN93807.1 - 1.2e-68 231.5 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF3452 PF11934.3 EDN93809.1 - 0.15 11.3 0.3 2.7 7.3 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3452) Ribosomal_L12 PF00542.14 EDN93810.1 - 4e-19 68.3 2.7 4e-19 68.3 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain YejG PF13989.1 EDN93810.1 - 0.066 13.2 0.0 0.083 12.9 0.0 1.2 1 1 0 1 1 1 0 YejG-like protein AAA_5 PF07728.9 EDN93811.1 - 3.5e-123 405.8 1.1 1.7e-21 76.4 0.0 10.0 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EDN93811.1 - 2.4e-28 98.9 0.1 0.00039 20.6 0.0 7.3 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EDN93811.1 - 7.4e-28 96.7 0.0 5.6e-11 42.1 0.0 7.3 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN93811.1 - 1.2e-26 93.8 5.5 0.00052 20.8 0.0 8.5 8 1 0 8 8 6 5 AAA domain AAA_33 PF13671.1 EDN93811.1 - 5.9e-26 91.0 0.0 0.0048 16.7 0.0 8.7 9 1 0 9 9 7 6 AAA domain AAA_22 PF13401.1 EDN93811.1 - 7.3e-23 81.1 6.2 0.00074 19.6 0.0 8.9 9 1 0 9 9 8 5 AAA domain AAA_16 PF13191.1 EDN93811.1 - 9.1e-22 77.9 19.9 0.00024 21.1 0.4 8.4 8 1 0 8 8 6 5 AAA ATPase domain AAA_14 PF13173.1 EDN93811.1 - 8.7e-21 74.1 0.0 0.00018 21.4 0.0 7.9 7 1 1 8 8 7 3 AAA domain AAA_18 PF13238.1 EDN93811.1 - 5e-20 72.1 0.1 0.0071 16.6 0.0 7.6 6 0 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.1 EDN93811.1 - 3e-19 69.4 2.3 0.00014 21.8 0.0 7.9 8 0 0 8 8 6 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EDN93811.1 - 3.4e-19 68.9 0.2 0.033 13.6 0.0 6.7 6 0 0 6 6 6 5 Sigma-54 interaction domain ABC_tran PF00005.22 EDN93811.1 - 1.8e-17 63.9 5.2 0.001 19.3 0.0 7.9 7 0 0 7 7 7 3 ABC transporter T2SE PF00437.15 EDN93811.1 - 1.5e-15 56.8 0.2 0.027 13.3 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein UPF0079 PF02367.12 EDN93811.1 - 4.7e-14 52.0 5.0 0.0085 15.7 0.0 6.3 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EDN93811.1 - 4.9e-14 52.3 3.7 0.13 11.9 0.0 6.6 6 0 0 6 6 6 3 NACHT domain AAA_19 PF13245.1 EDN93811.1 - 5.5e-14 51.6 2.8 0.0019 17.9 0.0 6.8 6 0 0 6 6 6 2 Part of AAA domain RNA_helicase PF00910.17 EDN93811.1 - 8.1e-14 51.7 1.6 0.11 12.6 0.0 7.4 7 0 0 7 7 7 2 RNA helicase DUF258 PF03193.11 EDN93811.1 - 3.6e-13 49.0 2.2 0.32 10.1 0.1 6.0 6 0 0 6 6 6 4 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EDN93811.1 - 5.5e-13 48.4 6.5 0.55 9.2 0.0 8.6 9 0 0 9 9 9 3 Zeta toxin AAA_29 PF13555.1 EDN93811.1 - 1.3e-12 47.0 0.1 0.068 12.7 0.0 6.4 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_28 PF13521.1 EDN93811.1 - 1.8e-12 47.5 2.6 0.097 12.6 0.0 7.3 7 0 0 7 7 6 1 AAA domain Miro PF08477.8 EDN93811.1 - 7.3e-12 45.8 0.9 2.5 8.6 0.0 7.0 6 0 0 6 6 6 1 Miro-like protein AAA_25 PF13481.1 EDN93811.1 - 6.9e-11 41.9 1.1 0.18 11.1 0.0 5.6 5 0 0 5 5 5 3 AAA domain Arch_ATPase PF01637.13 EDN93811.1 - 8.4e-11 42.0 0.0 0.36 10.5 0.0 6.8 6 0 0 6 6 6 1 Archaeal ATPase MobB PF03205.9 EDN93811.1 - 8.9e-11 41.6 3.5 1.2 8.8 0.0 6.6 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EDN93811.1 - 1.1e-10 40.9 2.3 0.042 12.9 0.0 6.3 5 1 1 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EDN93811.1 - 5e-10 39.1 0.9 0.24 10.8 0.0 5.9 6 0 0 6 6 5 3 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 EDN93811.1 - 5.4e-09 35.9 0.1 0.31 10.5 0.0 6.3 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EDN93811.1 - 1.5e-08 34.0 1.2 6.5 5.8 0.0 8.0 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDN93811.1 - 1.7e-07 30.8 0.0 0.3 10.4 0.0 5.5 6 0 0 6 6 5 1 IstB-like ATP binding protein cobW PF02492.14 EDN93811.1 - 2.4e-07 30.3 2.0 1.7 8.0 0.0 6.0 6 0 0 6 6 6 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EDN93811.1 - 3.7e-07 29.7 2.7 0.033 13.6 0.0 5.4 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EDN93811.1 - 6.8e-07 28.9 1.0 3.1 7.2 0.0 5.7 6 0 0 6 6 6 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EDN93811.1 - 1.3e-06 28.3 0.4 4.7 7.2 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EDN93811.1 - 3.7e-06 26.7 5.4 0.46 10.1 0.0 5.5 5 0 0 5 5 5 2 NTPase AAA_7 PF12775.2 EDN93811.1 - 6.7e-05 22.1 3.1 0.42 9.6 0.0 4.6 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 AAA_6 PF12774.2 EDN93811.1 - 0.00016 21.3 0.1 13 5.2 0.0 5.6 7 0 0 7 7 5 0 Hydrolytic ATP binding site of dynein motor region D1 CbiA PF01656.18 EDN93811.1 - 0.00025 20.5 2.4 1 8.7 0.0 4.1 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 EDN93811.1 - 0.0004 19.6 0.1 3.3 6.8 0.0 4.7 5 0 0 5 5 5 1 PhoH-like protein KaiC PF06745.8 EDN93811.1 - 0.0013 17.9 1.5 12 4.9 0.0 5.5 5 1 1 6 6 5 0 KaiC ATP_bind_1 PF03029.12 EDN93811.1 - 0.0029 17.1 7.7 6.8 6.1 0.1 6.0 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 EDN93811.1 - 0.0055 16.2 0.0 11 5.4 0.0 4.6 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 EDN93811.1 - 0.012 15.2 1.0 2.9 7.4 0.0 4.5 6 0 0 6 6 4 0 Phosphoribulokinase / Uridine kinase family DBI_PRT PF02277.12 EDN93811.1 - 0.024 13.7 0.4 4.2 6.3 0.1 3.2 3 0 0 3 3 3 0 Phosphoribosyltransferase tRNA_lig_kinase PF08303.6 EDN93811.1 - 0.025 14.4 0.9 0.086 12.7 0.0 2.4 3 0 0 3 3 1 0 tRNA ligase kinase domain SHP PF03579.8 EDN93812.1 - 2.4 7.6 4.4 0.73 9.2 0.8 1.7 2 0 0 2 2 2 0 Small hydrophobic protein NOC3p PF07540.6 EDN93813.1 - 7.1e-34 115.9 0.1 3e-33 113.9 0.1 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EDN93813.1 - 1.5e-29 102.5 0.1 4e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family UPF0113 PF03657.8 EDN93814.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EDN93814.1 - 0.043 13.8 0.1 0.17 12.0 0.0 2.0 2 1 1 3 3 3 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EDN93814.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 PUA domain Zn_clus PF00172.13 EDN93815.1 - 0.00079 19.2 8.3 0.0012 18.6 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN93816.1 - 9e-32 110.1 38.0 9e-32 110.1 26.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Bestrophin PF01062.16 EDN93816.1 - 0.075 11.9 3.7 0.15 11.0 2.6 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Cad PF03596.8 EDN93816.1 - 0.17 11.5 2.6 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Cadmium resistance transporter DEAD PF00270.24 EDN93818.1 - 1.7e-29 102.5 0.0 2.7e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN93818.1 - 1.2e-16 60.2 0.0 2.6e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN93818.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BCS1_N PF08740.6 EDN93819.1 - 4e-54 183.0 0.9 9.3e-54 181.8 0.6 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN93819.1 - 8.4e-18 64.8 2.7 6.8e-08 32.7 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN93819.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN93819.1 - 0.0057 17.4 0.0 0.0057 17.4 0.0 3.3 3 3 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EDN93819.1 - 0.0085 15.8 0.0 0.053 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDN93819.1 - 0.012 14.9 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDN93819.1 - 0.047 12.7 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN93819.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EDN93819.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.5 3 1 0 3 3 3 0 ABC transporter UCH PF00443.24 EDN93820.1 - 3.2e-76 255.9 0.0 1.8e-43 148.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN93820.1 - 8.2e-16 58.2 0.0 3.6e-08 33.1 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EDN93820.1 - 2.3e-11 43.9 0.0 8.5e-11 42.1 0.0 2.1 1 0 0 1 1 1 1 DUSP domain DUF3735 PF12537.3 EDN93823.1 - 0.068 13.2 0.9 0.087 12.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) FAD_binding_6 PF00970.19 EDN93828.1 - 6.9e-26 90.2 0.0 1.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDN93828.1 - 1.5e-24 86.6 0.0 2.2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDN93828.1 - 1.2e-05 25.3 0.0 0.0008 19.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDN93828.1 - 0.0084 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF788 PF05620.6 EDN93829.1 - 2.8e-41 141.2 0.1 3.1e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_11 PF13414.1 EDN93830.1 - 4.3e-40 135.2 21.7 6.5e-12 44.9 0.5 8.1 6 1 2 9 9 9 7 TPR repeat TPR_2 PF07719.12 EDN93830.1 - 2.3e-37 123.9 17.7 2.4e-06 27.0 0.0 11.4 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 EDN93830.1 - 7.5e-36 120.2 14.5 6.6e-08 31.8 0.0 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDN93830.1 - 4.9e-32 107.2 8.0 1.9e-05 24.0 0.1 9.9 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 EDN93830.1 - 3.6e-29 100.7 16.6 1.6e-21 76.1 0.1 5.0 4 2 3 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDN93830.1 - 7e-27 93.4 12.4 1.4e-06 28.7 0.0 8.8 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN93830.1 - 4e-26 90.7 12.3 8.1e-08 32.0 0.0 8.2 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDN93830.1 - 2.6e-24 85.3 11.8 4.6e-08 33.2 0.1 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN93830.1 - 2.8e-23 80.2 5.5 0.0038 17.7 0.0 10.1 9 2 3 12 12 11 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDN93830.1 - 1.5e-18 65.3 6.0 0.0009 19.2 0.0 9.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN93830.1 - 3.9e-13 48.1 3.6 0.019 14.7 0.0 8.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN93830.1 - 5.3e-12 45.3 15.8 0.18 12.3 0.0 10.2 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN93830.1 - 1.3e-07 31.3 1.6 0.012 15.3 0.0 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDN93830.1 - 0.00051 19.8 0.7 0.41 10.5 0.0 4.3 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 EDN93830.1 - 0.0097 14.7 4.9 0.29 9.8 0.0 3.2 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 Sel1 PF08238.7 EDN93830.1 - 0.012 16.1 10.5 5.6 7.7 0.0 6.0 7 0 0 7 7 6 0 Sel1 repeat DUF3856 PF12968.2 EDN93830.1 - 0.036 13.8 1.9 4.2 7.1 0.5 4.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 EDN93830.1 - 0.047 13.5 2.9 11 5.9 0.0 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 EDN93830.1 - 0.053 12.9 3.4 13 5.1 1.4 3.9 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.1 EDN93830.1 - 0.063 13.4 0.2 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat APP_E2 PF12925.2 EDN93830.1 - 0.38 10.2 3.0 16 5.0 0.0 3.3 3 2 1 4 4 4 0 E2 domain of amyloid precursor protein zf-RING_2 PF13639.1 EDN93832.1 - 6e-09 35.5 5.1 6e-09 35.5 3.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EDN93832.1 - 1.8e-08 33.9 4.2 1.8e-08 33.9 2.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDN93832.1 - 4.1e-08 33.2 1.3 4.1e-08 33.2 0.9 1.9 3 0 0 3 3 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDN93832.1 - 6.3e-06 26.1 4.7 6.3e-06 26.1 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN93832.1 - 1.3e-05 24.7 7.6 1.6e-05 24.4 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN93832.1 - 3.3e-05 23.4 2.5 3.3e-05 23.4 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN93832.1 - 9.2e-05 22.2 2.7 0.00052 19.7 1.8 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EDN93832.1 - 0.0016 17.9 2.8 0.0022 17.4 1.1 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 EDN93832.1 - 0.0056 16.3 7.6 0.0062 16.1 3.5 2.1 2 0 0 2 2 2 1 PHD-finger zf-RING_4 PF14570.1 EDN93832.1 - 0.031 13.8 2.1 0.058 12.9 1.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDN93832.1 - 0.032 13.9 4.0 0.081 12.6 2.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EDN93832.1 - 0.046 13.7 6.2 0.73 9.9 2.7 2.6 2 0 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.1 EDN93832.1 - 0.22 11.2 6.8 0.18 11.5 0.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EDN93832.1 - 0.24 11.3 4.9 1.6 8.7 3.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain C1_1 PF00130.17 EDN93832.1 - 0.33 10.6 6.8 0.18 11.5 1.0 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EDN93832.1 - 0.69 9.9 7.6 0.46 10.5 3.4 2.1 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.1 EDN93832.1 - 1.9 8.4 6.5 0.46 10.4 1.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING peroxidase PF00141.18 EDN93835.1 - 6.2e-48 163.2 0.0 8.7e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.20 EDN93837.1 - 3.4e-47 160.7 0.0 1.6e-46 158.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93837.1 - 3e-28 98.6 0.0 7.9e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN93837.1 - 0.02 13.8 0.1 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EDN93837.1 - 0.056 12.4 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Velvet PF11754.3 EDN93840.1 - 1.1e-53 181.8 0.0 1.6e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor CTP_synth_N PF06418.9 EDN93841.1 - 2e-95 319.0 9.6 1.8e-88 296.1 0.2 2.1 1 1 1 2 2 2 2 CTP synthase N-terminus GATase PF00117.23 EDN93841.1 - 8.9e-43 145.9 0.0 2.2e-21 76.1 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDN93841.1 - 0.00027 20.4 0.1 0.0012 18.3 0.0 2.0 1 1 1 2 2 2 1 Peptidase C26 Pkinase PF00069.20 EDN93842.1 - 1.3e-09 37.5 0.4 1.3e-05 24.5 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93842.1 - 0.028 13.4 0.8 1.2 8.1 0.0 2.9 2 1 0 2 2 2 0 Protein tyrosine kinase Sugar_tr PF00083.19 EDN93843.1 - 1.1e-91 307.6 28.5 1.3e-91 307.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN93843.1 - 1.4e-27 96.3 23.0 1.4e-27 96.3 15.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.10 EDN93843.1 - 0.0072 16.3 1.8 0.03 14.3 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family Pik1 PF11522.3 EDN93844.1 - 5.3e-20 70.8 0.1 1.4e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF1811 PF08838.5 EDN93844.1 - 0.13 12.2 0.2 0.51 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) UNC-93 PF05978.11 EDN93845.1 - 1.7e-10 40.6 7.3 7.4e-10 38.5 5.1 2.2 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EDN93845.1 - 2.1e-10 39.8 33.4 3.6e-10 39.0 23.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.7 EDN93845.1 - 1.7 8.4 6.4 12 5.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function, DUF485 NuA4 PF09340.5 EDN93846.1 - 0.13 11.8 0.9 0.37 10.4 0.6 1.8 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 PRAP PF15314.1 EDN93847.1 - 3.6 7.9 7.5 7.8 6.8 5.2 1.6 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Spo7 PF03907.8 EDN93850.1 - 2.6e-82 275.4 0.0 3.3e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 EDN93851.1 - 2.7e-26 92.8 0.1 8.8e-26 91.1 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN93851.1 - 5e-16 58.9 0.0 4e-14 52.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN93851.1 - 5.9e-13 48.7 0.0 1.1e-11 44.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN93851.1 - 2e-05 24.1 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EDN93851.1 - 3.4e-05 23.0 0.0 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EDN93851.1 - 0.00062 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDN93851.1 - 0.0055 15.5 0.0 0.0081 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EDN93851.1 - 0.0061 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EDN93851.1 - 0.0091 16.2 0.4 0.044 14.0 0.3 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EDN93851.1 - 0.024 14.1 0.0 13 5.1 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EDN93851.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EDN93851.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EDN93851.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EDN93851.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.9 EDN93852.1 - 1.6e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN93852.1 - 2.6e-08 34.1 0.1 1.2e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN93852.1 - 0.032 14.2 0.3 4.9 7.1 0.0 2.9 1 1 3 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DUF4451 PF14616.1 EDN93854.1 - 0.024 14.4 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Abhydrolase_6 PF12697.2 EDN93855.1 - 2.6e-18 66.7 0.0 3.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN93855.1 - 0.00035 20.3 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN93855.1 - 0.00039 20.0 0.0 0.00077 19.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDN93855.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EDN93855.1 - 0.029 12.8 0.0 0.052 12.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family UbiA PF01040.13 EDN93857.1 - 9.1e-28 97.1 14.1 1.3e-27 96.6 9.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Thi4 PF01946.12 EDN93860.1 - 7.8e-107 355.5 0.1 9.6e-107 355.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EDN93860.1 - 2.6e-07 29.8 0.5 7e-07 28.4 0.4 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN93860.1 - 4.4e-06 25.8 0.3 3.2e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN93860.1 - 0.0001 22.2 0.3 0.00027 20.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN93860.1 - 0.00017 21.4 0.8 0.00078 19.2 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EDN93860.1 - 0.0018 17.1 2.1 0.041 12.7 0.4 2.6 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN93860.1 - 0.0022 17.8 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN93860.1 - 0.0023 18.0 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN93860.1 - 0.014 14.5 0.1 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EDN93860.1 - 0.13 11.3 0.9 0.44 9.5 0.6 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDN93860.1 - 0.13 10.8 0.2 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Acyl-CoA_dh_1 PF00441.19 EDN93863.1 - 5.2e-24 85.0 0.6 7.5e-24 84.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN93863.1 - 1e-08 34.5 0.1 2.8e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN93863.1 - 1.8e-06 28.4 0.1 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN93863.1 - 0.0028 17.9 1.7 0.0028 17.9 1.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain adh_short PF00106.20 EDN93864.1 - 5.7e-10 39.3 0.0 7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EDN93864.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDN93864.1 - 1.8e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN93864.1 - 0.033 13.1 0.1 0.06 12.2 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Dpy-30 PF05186.8 EDN93864.1 - 0.17 11.4 0.4 0.64 9.5 0.0 2.0 3 0 0 3 3 3 0 Dpy-30 motif Xan_ur_permease PF00860.15 EDN93865.1 - 2.9e-69 233.4 37.3 8.2e-68 228.6 25.9 2.0 1 1 0 1 1 1 1 Permease family Pkinase PF00069.20 EDN93866.1 - 1.7e-12 47.0 0.0 2.1e-10 40.1 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN93866.1 - 1.2e-09 37.6 0.0 1.7e-08 33.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 EDN93868.1 - 3.7e-62 209.2 0.0 6.9e-62 208.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EDN93868.1 - 2.2e-39 135.2 0.1 5.6e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EDN93868.1 - 3.1e-22 79.1 0.0 7.2e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN93868.1 - 9.9e-07 28.5 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN93868.1 - 1.6e-06 28.1 0.0 5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDN93868.1 - 8.2e-06 25.9 0.1 0.00019 21.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN93868.1 - 1.7e-05 24.8 0.3 0.0016 18.4 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain ChlI PF13541.1 EDN93868.1 - 3e-05 23.5 0.0 8.8e-05 22.0 0.0 1.9 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 EDN93868.1 - 4.8e-05 24.1 0.0 0.00022 21.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EDN93868.1 - 0.00015 20.6 0.0 0.00031 19.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EDN93868.1 - 0.0002 20.4 0.0 0.0015 17.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EDN93868.1 - 0.0021 18.3 0.9 0.028 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDN93868.1 - 0.0046 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN93868.1 - 0.022 14.1 0.1 0.065 12.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 EDN93868.1 - 0.027 14.1 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EDN93868.1 - 0.027 14.1 0.1 1 9.0 0.0 2.9 2 1 1 3 3 3 0 NTPase ClpB_D2-small PF10431.4 EDN93868.1 - 0.035 14.0 0.2 0.035 14.0 0.1 2.6 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein DUF258 PF03193.11 EDN93868.1 - 0.04 13.1 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EDN93868.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EDN93868.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EDN93868.1 - 0.1 12.1 0.0 0.34 10.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDN93868.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ALIX_LYPXL_bnd PF13949.1 EDN93869.1 - 6.1e-13 48.3 0.2 1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV PAT1 PF09770.4 EDN93869.1 - 9.2 4.3 33.4 13 3.9 23.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BRO1 PF03097.13 EDN93870.1 - 1.1e-100 337.1 14.0 5.1e-94 315.1 4.6 3.3 2 1 1 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDN93870.1 - 1.8e-49 168.3 5.5 1.8e-49 168.3 3.8 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Myosin_tail_1 PF01576.14 EDN93870.1 - 0.0095 13.7 8.2 0.016 12.9 5.7 1.3 1 0 0 1 1 1 1 Myosin tail DUF3012 PF11216.3 EDN93870.1 - 0.18 11.5 1.4 0.59 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) NYD-SP28 PF14772.1 EDN93870.1 - 1.8 8.6 8.5 0.16 12.1 0.7 3.0 3 1 0 3 3 3 0 Sperm tail DUF4164 PF13747.1 EDN93870.1 - 7.9 6.6 8.8 1.3 9.1 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) CTDII PF01556.13 EDN93871.1 - 1.6e-27 95.2 2.0 1.8e-22 78.9 0.5 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EDN93871.1 - 5.1e-22 77.3 0.7 8.5e-22 76.6 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDN93871.1 - 4.2e-10 39.5 22.2 1e-09 38.2 15.4 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EDN93871.1 - 7.6 6.2 9.5 4.6 6.9 0.7 2.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family SAP30_Sin3_bdg PF13867.1 EDN93872.1 - 5.3e-17 61.4 0.5 6e-16 58.0 0.4 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 HeLo PF14479.1 EDN93873.1 - 0.052 13.2 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Fungal_trans PF04082.13 EDN93874.1 - 3.7e-55 186.6 0.5 6.1e-55 185.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EDN93874.1 - 0.00052 20.1 1.3 0.00052 20.1 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN93874.1 - 0.0034 17.5 4.3 0.044 14.1 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN93874.1 - 0.0054 16.9 1.1 0.0054 16.9 0.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2415 PF10313.4 EDN93876.1 - 1.4e-14 53.4 0.0 4e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HSP70 PF00012.15 EDN93877.1 - 6.3e-257 853.3 14.5 7.3e-257 853.1 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN93877.1 - 1.2e-13 50.3 0.9 1.2e-13 50.3 0.7 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDN93877.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaG_DnaB_bind PF08278.6 EDN93877.1 - 2.8 8.1 5.2 0.89 9.7 0.9 2.2 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding eIF3g PF12353.3 EDN93878.1 - 1.4e-45 154.3 3.7 2.3e-45 153.6 2.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EDN93878.1 - 4.7e-17 61.3 0.1 9e-17 60.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN93878.1 - 5.9e-12 45.4 0.1 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN93878.1 - 1e-07 31.6 0.3 2.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN93878.1 - 0.021 14.6 1.7 1.4 8.8 0.1 2.8 3 0 0 3 3 3 0 RNA binding motif NOT2_3_5 PF04153.13 EDN93881.1 - 3.1e-35 120.9 1.4 7.6e-35 119.7 1.0 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Fungal_trans_2 PF11951.3 EDN93882.1 - 6.3e-11 41.4 0.1 1.2e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.1 EDN93882.1 - 0.19 11.6 1.2 0.36 10.7 0.8 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3135 PF11333.3 EDN93883.1 - 0.12 12.5 0.0 0.63 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) SMC_N PF02463.14 EDN93886.1 - 1.3e-39 135.6 13.1 4.8e-39 133.8 9.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDN93886.1 - 4e-22 78.4 1.2 2.2e-21 76.0 0.3 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN93886.1 - 2.7e-06 27.5 0.4 2.7e-06 27.5 0.3 4.0 2 2 1 3 3 3 1 AAA domain MscS_porin PF12795.2 EDN93886.1 - 0.00068 19.0 27.0 0.00068 19.0 18.7 6.6 2 2 2 6 6 6 2 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EDN93886.1 - 0.2 10.7 39.4 0.3 10.2 2.6 6.8 3 2 4 7 7 7 0 Reovirus sigma C capsid protein MOSC PF03473.12 EDN93888.1 - 8.1e-21 73.8 0.0 1.5e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EDN93888.1 - 4.3e-12 45.7 0.0 9.8e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain 4HBT PF03061.17 EDN93889.1 - 2.4e-06 27.5 1.3 5.6e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Imm9 PF15561.1 EDN93890.1 - 0.13 11.8 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 9 MFS_1 PF07690.11 EDN93892.1 - 1.2e-38 132.8 43.2 1.2e-38 132.8 29.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN93892.1 - 5.8e-09 34.6 8.5 9.5e-09 33.9 5.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN93892.1 - 2.2e-05 23.2 16.0 2.2e-05 23.2 11.1 3.1 1 1 1 3 3 3 2 Sugar (and other) transporter Neurensin PF14927.1 EDN93892.1 - 0.46 9.8 0.0 0.46 9.8 0.0 4.2 3 1 2 5 5 5 0 Neurensin Fungal_trans PF04082.13 EDN93893.1 - 2.8e-07 29.6 0.1 4.8e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Proteasome PF00227.21 EDN93895.1 - 9e-57 191.4 0.1 1.2e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN93895.1 - 1.2e-10 40.4 0.1 2.6e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EDN93895.1 - 0.002 17.8 0.2 0.061 12.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 EDN93896.1 - 3e-97 326.2 0.0 3e-62 210.6 0.0 2.2 1 1 1 2 2 2 2 Spc97 / Spc98 family HECA PF15353.1 EDN93896.1 - 0.017 14.7 0.4 0.079 12.6 0.5 1.8 2 0 0 2 2 2 0 Headcase protein family homologue MTHFR PF02219.12 EDN93897.1 - 3.4e-112 374.2 0.0 4.8e-112 373.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Fungal_trans PF04082.13 EDN93898.1 - 3e-20 72.1 0.0 5.2e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EDN93898.1 - 9.5e-07 28.8 14.7 1.1e-05 25.4 0.8 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN93898.1 - 2.7e-05 24.1 14.2 0.0014 18.8 4.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EDN93898.1 - 0.0006 19.8 3.2 0.0017 18.4 2.2 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EDN93898.1 - 0.55 10.4 3.6 7.2 6.8 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDN93898.1 - 9.1 6.8 26.8 0.046 14.0 4.7 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type PTS_IIA PF02255.11 EDN93899.1 - 0.011 15.5 1.7 0.61 9.9 0.1 2.4 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit MMR_HSR1_C PF08438.5 EDN93899.1 - 0.17 12.1 1.8 0.18 12.0 0.2 1.7 2 0 0 2 2 2 0 GTPase of unknown function C-terminal MRP-L47 PF06984.8 EDN93902.1 - 6.1e-20 70.9 0.2 9.3e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 EDN93902.1 - 0.076 12.2 0.7 0.11 11.7 0.5 1.1 1 0 0 1 1 1 0 Clc-like GDI PF00996.13 EDN93903.1 - 2.1e-177 589.8 0.0 3.2e-177 589.2 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EDN93903.1 - 0.022 14.8 0.2 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N PF00107.21 EDN93904.1 - 3.1e-09 36.4 0.0 6.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN93904.1 - 2.4e-05 24.0 0.1 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box PF00646.28 EDN93907.1 - 3.8e-05 23.2 5.1 0.00016 21.2 1.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EDN93907.1 - 0.25 11.0 2.8 1.2 8.9 0.6 2.6 2 0 0 2 2 2 0 F-box-like Amidase PF01425.16 EDN93908.1 - 1.3e-21 76.9 11.4 7.5e-21 74.4 7.6 2.3 1 1 1 2 2 2 2 Amidase DUF2476 PF10630.4 EDN93908.1 - 0.0096 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2476) MFS_1 PF07690.11 EDN93909.1 - 1.2e-37 129.5 22.7 4.1e-28 98.1 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN93909.1 - 1.8e-10 40.0 6.0 1.8e-10 40.0 4.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EDN93909.1 - 7.4e-06 24.6 18.3 0.00013 20.4 2.0 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EDN93909.1 - 0.2 9.7 7.6 0.11 10.5 2.5 2.2 2 1 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.11 EDN93913.1 - 4.7e-29 101.2 34.0 4.7e-29 101.2 23.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ish1 PF10281.4 EDN93914.1 - 0.017 15.2 0.2 0.068 13.2 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein S1-P1_nuclease PF02265.11 EDN93915.1 - 5.5e-72 242.4 0.0 6.2e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease KH_3 PF13014.1 EDN93916.1 - 0.013 15.1 0.1 0.82 9.3 0.0 2.9 3 0 0 3 3 3 0 KH domain KH_1 PF00013.24 EDN93916.1 - 0.028 14.0 0.1 0.3 10.7 0.0 2.6 2 1 1 3 3 3 0 KH domain CT47 PF15623.1 EDN93916.1 - 0.061 13.0 13.1 0.08 12.6 9.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 MFMR PF07777.6 EDN93916.1 - 3.5 7.5 6.1 5.3 6.9 4.2 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR RR_TM4-6 PF06459.7 EDN93916.1 - 5 6.9 16.4 6.8 6.5 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GATA PF00320.22 EDN93917.1 - 5e-15 54.5 2.0 1.2e-14 53.3 1.4 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2353 PF09789.4 EDN93917.1 - 0.002 17.4 6.1 0.003 16.8 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Macoilin PF09726.4 EDN93917.1 - 0.0021 16.4 1.5 0.003 15.9 1.0 1.1 1 0 0 1 1 1 1 Transmembrane protein YscO PF07321.7 EDN93917.1 - 0.026 14.3 5.3 0.059 13.1 3.7 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO Fmp27_WPPW PF10359.4 EDN93917.1 - 0.046 12.1 3.3 0.066 11.6 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DegS PF05384.6 EDN93917.1 - 0.047 12.8 5.9 0.075 12.2 4.1 1.3 1 0 0 1 1 1 0 Sensor protein DegS APG6 PF04111.7 EDN93917.1 - 0.1 11.6 5.4 0.16 11.0 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EDN93917.1 - 0.12 12.2 9.5 0.41 10.5 6.6 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EDN93917.1 - 0.15 11.2 6.0 0.24 10.5 4.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArfGap PF01412.13 EDN93917.1 - 0.16 11.7 0.4 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf CENP-F_leu_zip PF10473.4 EDN93917.1 - 0.23 11.2 11.1 1.7 8.5 0.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EDN93917.1 - 0.31 11.1 6.7 0.7 9.9 4.7 1.6 1 1 0 1 1 1 0 DivIVA protein Pox_A_type_inc PF04508.7 EDN93917.1 - 0.5 10.2 5.2 1.1 9.1 1.4 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat IncA PF04156.9 EDN93917.1 - 0.54 9.8 4.9 1.1 8.8 3.4 1.4 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EDN93917.1 - 0.77 9.6 9.6 2 8.2 0.2 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Prefoldin_2 PF01920.15 EDN93917.1 - 2 8.2 7.6 0.93 9.2 1.6 2.3 1 1 0 2 2 2 0 Prefoldin subunit DNA_mis_repair PF01119.14 EDN93918.1 - 5.9e-18 64.4 0.0 2e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EDN93918.1 - 1.8e-13 50.3 0.1 2.2e-12 46.8 0.0 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN93918.1 - 9e-10 38.2 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EDN93918.1 - 4.9e-06 26.2 0.1 2.4e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain Aconitase PF00330.15 EDN93920.1 - 2.5e-48 164.7 0.0 3e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) SKN1 PF03935.10 EDN93922.1 - 9.9e-234 776.1 5.4 1.2e-233 775.8 3.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Red1 PF07964.6 EDN93923.1 - 0.17 10.0 4.0 0.28 9.3 2.7 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Tom22 PF04281.8 EDN93923.1 - 5.7 6.4 7.0 0.34 10.4 0.6 2.1 2 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF3716 PF12511.3 EDN93924.1 - 6.8e-14 51.2 5.5 1.1e-13 50.5 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Mit_KHE1 PF10173.4 EDN93925.1 - 1.3e-38 132.6 0.7 2.2e-38 132.0 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Herpes_UL37_2 PF07413.6 EDN93925.1 - 0.046 12.5 0.9 0.068 11.9 0.6 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF588 PF04535.7 EDN93926.1 - 2.4e-07 30.4 0.8 4.2e-07 29.6 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) MARVEL PF01284.18 EDN93926.1 - 0.0004 20.2 4.1 0.00067 19.4 2.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2569 PF10754.4 EDN93926.1 - 0.0093 16.1 1.0 0.0093 16.1 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) Ion_trans_2 PF07885.11 EDN93927.1 - 8.6e-31 105.4 15.1 7.1e-17 60.8 2.4 2.5 2 0 0 2 2 2 2 Ion channel Cutinase PF01083.17 EDN93928.1 - 2.9e-44 150.9 6.8 4.2e-44 150.4 4.7 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EDN93928.1 - 3.5e-05 23.3 0.3 5.6e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EDN93928.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) EphA2_TM PF14575.1 EDN93929.1 - 0.47 10.8 2.2 0.53 10.7 0.8 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain BTB PF00651.26 EDN93930.1 - 0.00016 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4288 PF14119.1 EDN93930.1 - 0.08 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DDE_1 PF03184.14 EDN93931.1 - 2.3e-21 75.9 6.0 1.3e-17 63.6 0.2 3.1 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN93931.1 - 2.7e-11 43.1 0.2 1.2e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN93931.1 - 0.011 15.4 0.1 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 EDN93931.1 - 0.014 15.5 0.1 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Cytidylate_kin PF02224.13 EDN93935.1 - 0.084 12.3 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase MFS_1 PF07690.11 EDN93936.1 - 8.1e-31 107.0 25.8 8.1e-31 107.0 17.9 1.6 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2763 PF10961.3 EDN93936.1 - 0.14 12.6 0.4 4.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) BTB PF00651.26 EDN93937.1 - 0.0002 21.3 0.0 0.00058 19.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain RVT_1 PF00078.22 EDN93938.1 - 3.9e-17 62.3 0.1 1.2e-12 47.6 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN93938.1 - 3.2e-15 56.2 0.4 1.1e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EDN93938.1 - 0.0047 16.2 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger BTB PF00651.26 EDN93939.1 - 0.0004 20.3 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pil1 PF13805.1 EDN93940.1 - 1.6e-104 348.8 4.6 2.5e-104 348.2 3.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 EDN93940.1 - 0.062 13.4 1.3 0.28 11.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DDE_1 PF03184.14 EDN93942.1 - 1e-48 165.3 0.0 1.7e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN93942.1 - 6.9e-11 41.5 0.7 5.2e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN93942.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN93942.1 - 0.019 14.8 7.3 0.042 13.8 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_37 PF13744.1 EDN93942.1 - 0.03 14.1 0.2 0.095 12.5 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDN93942.1 - 0.1 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 NUMOD1 domain DUF3435 PF11917.3 EDN93943.1 - 1.3e-36 126.2 0.0 2.3e-36 125.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) AAA_10 PF12846.2 EDN93944.1 - 1.1e-10 41.4 0.0 3e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EDN93944.1 - 8.6e-05 22.0 0.0 0.00094 18.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EDN93944.1 - 0.013 15.6 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN93944.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_34 PF13872.1 EDN93944.1 - 0.06 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF87 PF01935.12 EDN93944.1 - 0.077 12.7 0.0 2.3 7.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EDN93944.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EDN93944.1 - 0.12 12.3 0.1 0.56 10.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain HET PF06985.6 EDN93949.1 - 6.2e-23 81.5 0.5 6.2e-23 81.5 0.4 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RVT_2 PF07727.9 EDN93950.1 - 3e-50 170.4 0.0 3.5e-49 166.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN93950.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN93950.1 - 0.00017 21.1 0.7 0.0005 19.6 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN93950.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) zf-CCHC_4 PF14392.1 EDN93951.1 - 0.028 14.0 2.3 0.031 13.9 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN93951.1 - 0.41 10.3 10.2 2.2 8.0 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 EDN93953.1 - 1.5e-07 30.8 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN93953.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN93953.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN93953.1 - 0.047 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_61 PF03443.9 EDN93954.1 - 6.2e-65 219.0 0.0 7.9e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EDN93955.1 - 4.4e-37 127.6 73.3 6.5e-27 94.1 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN93955.1 - 2.4e-05 24.0 4.0 0.051 13.3 0.0 3.1 3 0 0 3 3 3 2 MFS_1 like family Fungal_trans PF04082.13 EDN93956.1 - 4.8e-16 58.4 0.9 7.5e-16 57.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SlyX PF04102.7 EDN93958.1 - 0.094 13.1 13.2 0.048 14.0 4.3 3.5 3 1 2 5 5 5 0 SlyX Vfa1 PF08432.5 EDN93958.1 - 0.35 10.8 12.6 0.84 9.6 8.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Chromo PF00385.19 EDN93959.1 - 0.00037 20.1 0.0 0.00092 18.8 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 EDN93959.1 - 0.071 13.0 0.1 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Filament PF00038.16 EDN93960.1 - 0.0011 18.5 0.9 0.0011 18.5 0.6 3.4 2 1 1 3 3 3 1 Intermediate filament protein DUF2664 PF10867.3 EDN93960.1 - 0.56 10.8 4.7 11 6.6 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2664) DUF948 PF06103.6 EDN93960.1 - 2.1 8.2 6.7 0.91 9.4 0.2 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TACC PF05010.9 EDN93960.1 - 4.8 6.8 18.4 1.6 8.4 9.8 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Striatin PF08232.7 EDN93960.1 - 5.4 7.3 20.6 0.17 12.1 0.8 4.1 3 1 0 4 4 4 0 Striatin family TP_methylase PF00590.15 EDN93961.1 - 1.2e-21 77.4 0.0 2e-21 76.6 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 EDN93961.1 - 0.14 11.8 0.1 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) zf-C2H2_jaz PF12171.3 EDN93962.1 - 2e-07 30.9 0.3 3.5e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 EDN93962.1 - 1.7e-05 24.6 12.8 1.7e-05 24.6 8.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 EDN93962.1 - 0.00013 22.0 0.6 0.00023 21.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF2217 PF10265.4 EDN93963.1 - 0.67 8.6 3.0 0.9 8.2 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TPR_MLP1_2 PF07926.7 EDN93964.1 - 0.29 10.8 2.5 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein p450 PF00067.17 EDN93965.1 - 9.9e-52 175.9 0.0 1.9e-51 175.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Apc15p PF05841.6 EDN93967.1 - 0.42 11.3 4.5 0.51 11.0 3.1 1.1 1 0 0 1 1 1 0 Apc15p protein DASH_Ask1 PF08655.5 EDN93968.1 - 3.7e-32 109.9 0.2 6e-32 109.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 RicinB_lectin_2 PF14200.1 EDN93971.1 - 6e-19 68.3 0.3 1.9e-15 57.1 0.4 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EDN93971.1 - 0.055 13.4 0.1 0.25 11.3 0.0 1.9 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Aa_trans PF01490.13 EDN93972.1 - 3e-30 105.0 25.0 3e-30 105.0 17.3 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Peptidase_C15 PF01470.12 EDN93973.1 - 4.9e-20 72.2 0.0 3.8e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 Pyroglutamyl peptidase ChiC PF06483.6 EDN93973.1 - 0.093 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Chitinase C But2 PF09792.4 EDN93974.1 - 5.6e-06 26.1 0.4 9e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain But2 PF09792.4 EDN93977.1 - 0.00035 20.3 1.2 0.00055 19.6 0.9 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AMP-binding PF00501.23 EDN93979.1 - 1.6e-27 95.9 0.0 3.8e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme DUF1349 PF07081.6 EDN93980.1 - 2.8e-19 69.1 0.0 3.5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) REV PF00424.13 EDN93981.1 - 0.35 10.7 3.7 0.53 10.2 2.6 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) MAM PF00629.18 EDN93982.1 - 0.085 12.6 0.1 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 MAM domain Herpes_LMP1 PF05297.6 EDN93984.1 - 0.47 9.3 3.1 0.53 9.1 2.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) O-FucT PF10250.4 EDN93985.1 - 5.3e-10 38.9 0.6 1.4e-09 37.5 0.4 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1155 PF06633.6 EDN93985.1 - 0.078 12.2 0.2 0.078 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) CorA PF01544.13 EDN93987.1 - 3.1e-41 141.3 0.3 3.8e-40 137.7 0.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Guanylate_kin PF00625.16 EDN93987.1 - 0.11 11.9 0.8 0.27 10.6 0.5 1.6 1 0 0 1 1 1 0 Guanylate kinase Glyco_hydro_88 PF07470.8 EDN93990.1 - 4.8e-85 285.5 4.5 5.6e-85 285.3 3.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 EDN93990.1 - 0.0067 16.8 1.5 4.4 7.7 0.0 3.1 3 1 0 3 3 3 2 Prenyltransferase-like Pectate_lyase_3 PF12708.2 EDN93991.1 - 4.2e-87 291.9 26.0 8.1e-71 238.7 4.1 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EDN93991.1 - 1.1e-06 27.9 4.1 0.0015 17.9 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF2265 PF10023.4 EDN93993.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Glyco_hydro_71 PF03659.9 EDN93994.1 - 1.9e-138 461.1 6.9 2.9e-138 460.5 4.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SOG2 PF10428.4 EDN93994.1 - 5.4 5.5 15.4 7.1 5.1 10.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TBCA PF02970.11 EDN93995.1 - 2.9e-13 49.6 5.2 3.6e-13 49.3 3.6 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF4315 PF14193.1 EDN93995.1 - 0.016 15.1 1.5 0.02 14.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) THOC7 PF05615.8 EDN93996.1 - 8e-41 139.5 8.5 8e-41 139.5 5.9 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 DUF2228 PF10228.4 EDN93996.1 - 0.064 12.8 2.0 0.092 12.2 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) AAA_23 PF13476.1 EDN93996.1 - 0.18 12.1 8.9 0.29 11.4 6.2 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EDN93996.1 - 3.2 5.5 4.8 4.2 5.0 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EDN93996.1 - 6.9 5.5 11.2 11 4.8 7.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Elongin_A PF06881.6 EDN93997.1 - 3.8e-22 78.7 1.0 3.8e-22 78.7 0.7 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 EDN93998.1 - 2.7e-24 84.3 0.2 3.7e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN93998.1 - 3.7e-15 55.3 0.3 3.7e-15 55.3 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN93998.1 - 3.6e-05 23.9 0.1 0.00012 22.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain MCR_beta_N PF02783.10 EDN93998.1 - 0.11 11.9 0.2 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Cellulase PF00150.13 EDN93999.1 - 9.1e-17 61.1 2.9 2.1e-16 59.9 2.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DAGK_cat PF00781.19 EDN94000.1 - 4.4e-25 87.5 0.0 8.8e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain 6PGD PF00393.14 EDN94003.1 - 1.2e-133 444.8 0.0 1.5e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDN94003.1 - 1.3e-51 174.6 0.0 2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EDN94003.1 - 0.056 13.5 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EDN94003.1 - 0.065 12.3 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDN94003.1 - 0.075 12.6 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.17 EDN94004.1 - 7.6e-16 57.5 0.0 1.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94004.1 - 6.3e-10 38.8 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN94004.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EDN94004.1 - 0.06 12.8 1.1 0.26 10.8 0.2 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain p450 PF00067.17 EDN94005.1 - 1.8e-64 217.9 0.0 2.4e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF605 PF04652.11 EDN94006.1 - 1.6 8.0 11.3 1.8 7.8 7.9 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 EDN94006.1 - 1.8 6.4 13.7 2.1 6.2 9.5 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SWI-SNF_Ssr4 PF08549.5 EDN94007.1 - 2.7e-167 558.0 26.4 5.5e-167 557.0 18.3 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Ppx-GppA PF02541.11 EDN94008.1 - 9.1e-40 136.6 0.0 3.6e-39 134.6 0.0 1.8 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 EDN94008.1 - 0.011 14.2 0.1 0.021 13.3 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family TPT PF03151.11 EDN94010.1 - 2.5e-32 111.6 7.8 2.5e-32 111.6 5.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDN94010.1 - 5.1e-06 25.6 14.6 5.1e-06 25.6 10.1 1.8 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EDN94010.1 - 0.061 13.3 30.7 0.029 14.3 2.6 3.0 3 1 0 3 3 3 0 EamA-like transporter family Glyco_hydro_15 PF00723.16 EDN94011.1 - 3e-52 177.6 0.0 1.2e-47 162.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 DUF1752 PF08550.5 EDN94013.1 - 3.2e-11 42.6 4.5 6e-11 41.7 3.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Indigoidine_A PF04227.7 EDN94014.1 - 5.7e-105 350.7 0.2 8.9e-105 350.1 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EDN94014.1 - 7.1e-13 48.3 1.4 4.4e-07 29.3 0.1 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase adh_short PF00106.20 EDN94016.1 - 1.4e-24 86.8 2.4 4e-24 85.4 1.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN94016.1 - 4.6e-15 56.0 0.3 6.6e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN94016.1 - 7.5e-08 32.2 3.3 1.7e-06 27.8 2.2 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN94016.1 - 4.3e-07 30.1 0.1 1.4e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN94016.1 - 5.2e-05 22.8 0.2 0.00012 21.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN94016.1 - 0.0091 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN94016.1 - 0.0091 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EDN94016.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lipase_GDSL_3 PF14606.1 EDN94016.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Saccharop_dh PF03435.13 EDN94016.1 - 0.25 10.2 2.2 8.7 5.2 0.0 2.1 1 1 0 2 2 2 0 Saccharopine dehydrogenase Rad21_Rec8_N PF04825.8 EDN94017.1 - 1.9e-39 134.0 0.0 3.3e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDN94017.1 - 3e-08 32.7 0.2 7.3e-08 31.4 0.1 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EDN94017.1 - 0.0014 18.2 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein ABC_trans_N PF14510.1 EDN94017.1 - 0.0017 18.3 0.2 2.2 8.4 0.2 2.8 2 0 0 2 2 2 2 ABC-transporter extracellular N-terminal E1-E2_ATPase PF00122.15 EDN94018.1 - 3e-73 245.6 0.1 5.8e-73 244.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN94018.1 - 6.5e-38 130.0 0.8 1.9e-37 128.5 0.5 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EDN94018.1 - 4.9e-19 67.5 0.0 1e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 EDN94018.1 - 2.7e-18 67.1 0.5 6.2e-18 65.9 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN94018.1 - 6e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN94018.1 - 7.7e-08 32.7 0.1 3.7e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN94018.1 - 9.3e-05 22.1 1.1 0.00017 21.2 0.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase COG4 PF08318.7 EDN94019.1 - 5.7e-97 324.4 0.0 1.1e-96 323.5 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein SAP PF02037.22 EDN94020.1 - 1.5e-06 27.5 0.1 4.7e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 SAP domain WD40 PF00400.27 EDN94021.1 - 0.00011 21.8 4.4 0.38 10.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.7 EDN94021.1 - 0.0012 18.4 0.0 0.52 10.0 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF2583 PF10762.4 EDN94021.1 - 0.041 14.0 0.4 0.083 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) MFS_1 PF07690.11 EDN94025.1 - 1.5e-45 155.4 30.8 2e-45 155.0 21.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN94025.1 - 2.4e-13 49.4 8.2 2.4e-13 49.4 5.7 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 EDN94025.1 - 0.013 13.6 0.5 0.021 12.9 0.3 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.15 EDN94025.1 - 0.19 9.7 8.2 0.27 9.2 1.0 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Macoilin PF09726.4 EDN94026.1 - 1.1 7.5 18.5 1.1 7.4 12.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2215 PF10225.4 EDN94026.1 - 1.3 8.3 4.8 2.9 7.2 3.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Sld5 PF05916.6 EDN94027.1 - 2.5e-08 34.1 0.3 4.6e-08 33.3 0.1 1.6 2 0 0 2 2 2 1 GINS complex protein PAT1 PF09770.4 EDN94028.1 - 0.45 8.6 11.9 0.55 8.3 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase_C PF00433.19 EDN94028.1 - 1.3 9.5 5.0 1.5 9.3 2.3 2.4 2 1 0 2 2 2 0 Protein kinase C terminal domain Orthopox_F8 PF05886.6 EDN94028.1 - 2.2 8.1 6.3 2.2 8.1 0.3 2.7 1 1 0 2 2 2 0 Orthopoxvirus F8 protein Bul1_N PF04425.7 EDN94028.1 - 6.2 5.2 10.2 14 4.1 7.1 1.7 1 1 0 1 1 1 0 Bul1 N terminus Rhodanese PF00581.15 EDN94030.1 - 6.3e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF3263 PF11662.3 EDN94033.1 - 0.15 11.5 0.0 0.85 9.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3263) AIRC PF00731.15 EDN94035.1 - 5.6e-60 200.9 2.5 5.6e-60 200.9 1.7 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 EDN94035.1 - 4.9e-54 182.2 0.0 8.2e-54 181.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EDN94035.1 - 7.2e-12 45.4 0.0 3.7e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 EDN94035.1 - 3.2e-05 23.1 0.0 6.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 EDN94035.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 EDN94035.1 - 0.0004 20.6 0.0 0.24 11.7 0.0 2.6 2 1 0 2 2 2 2 XdhC Rossmann domain NAD_binding_2 PF03446.10 EDN94035.1 - 0.0071 16.1 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP-grasp_3 PF02655.9 EDN94035.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Auxin_repressed PF05564.7 EDN94038.1 - 1 9.9 7.1 1.1 9.9 3.1 2.3 2 1 1 3 3 3 0 Dormancy/auxin associated protein DUF328 PF03883.9 EDN94039.1 - 0.046 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF328) CSTF2_hinge PF14327.1 EDN94040.1 - 7.2e-30 102.9 2.2 7.2e-30 102.9 1.5 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EDN94040.1 - 3.5e-22 77.8 0.0 5.1e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94040.1 - 1.9e-16 59.8 0.0 3.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EDN94040.1 - 2.7e-08 32.9 4.7 2.7e-08 32.9 3.3 2.7 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EDN94040.1 - 6.5e-08 32.3 0.0 9.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Band_7 PF01145.20 EDN94041.1 - 1.4e-24 86.9 1.1 2.2e-24 86.3 0.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EDN94041.1 - 0.03 13.6 2.9 0.044 13.0 2.0 1.3 1 1 0 1 1 1 0 MraW methylase family Peptidase_S9 PF00326.16 EDN94042.1 - 2.2e-52 177.3 0.7 7.5e-52 175.6 0.5 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN94042.1 - 3.1e-06 26.9 0.0 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDN94042.1 - 0.00097 17.7 0.2 0.024 13.1 0.2 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DDE_1 PF03184.14 EDN94047.1 - 1.2e-37 129.1 0.0 1.8e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN94047.1 - 0.0002 21.1 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDN94047.1 - 0.001 18.9 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.11 EDN94047.1 - 0.0073 15.8 0.1 0.027 14.0 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EDN94047.1 - 0.083 12.5 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain NUMOD1 PF07453.8 EDN94047.1 - 0.084 12.7 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain Rap1-DNA-bind PF09197.5 EDN94047.1 - 0.44 11.1 2.5 1.5 9.4 0.3 2.6 2 1 0 2 2 2 0 Rap1, DNA-binding RdRP PF05183.7 EDN94048.1 - 1.4e-163 545.7 0.0 2e-163 545.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EDN94048.1 - 0.0083 16.0 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HAUS6_N PF14661.1 EDN94050.1 - 0.0014 18.0 0.8 0.0021 17.4 0.6 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF3373 PF11853.3 EDN94050.1 - 0.0015 17.1 0.6 0.0018 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) bZIP_1 PF00170.16 EDN94050.1 - 0.016 15.1 3.6 0.016 15.1 2.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor DivIVA PF05103.8 EDN94050.1 - 0.13 12.3 5.6 21 5.1 5.6 2.4 1 1 1 2 2 2 0 DivIVA protein HALZ PF02183.13 EDN94050.1 - 1.3 8.7 5.6 0.21 11.3 0.9 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EDN94050.1 - 3.9 7.8 6.5 1.8 8.9 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) THOC7 PF05615.8 EDN94050.1 - 4.6 7.5 11.7 0.29 11.3 3.7 2.3 2 1 1 3 3 3 0 Tho complex subunit 7 SH3_9 PF14604.1 EDN94052.1 - 2.5e-10 39.7 0.0 4.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN94052.1 - 1.1e-08 34.2 0.0 1.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDN94052.1 - 1.6e-06 27.5 0.0 3.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rifin_STEVOR PF02009.11 EDN94052.1 - 0.0067 16.1 0.4 0.015 15.0 0.3 1.5 1 1 0 1 1 1 1 Rifin/stevor family Otopetrin PF03189.8 EDN94052.1 - 0.011 14.7 0.1 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Otopetrin DUF1049 PF06305.6 EDN94052.1 - 0.013 14.9 0.2 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Plasmodium_Vir PF05795.6 EDN94052.1 - 0.089 11.9 2.3 0.2 10.8 1.6 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein OAD_gamma PF04277.8 EDN94052.1 - 0.14 12.5 1.9 0.55 10.6 0.0 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Amnionless PF14828.1 EDN94052.1 - 0.16 10.3 0.1 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless Csm1 PF12539.3 EDN94054.1 - 2e-27 95.5 0.0 3.6e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 GAS PF13851.1 EDN94054.1 - 0.0018 17.5 3.6 0.0018 17.5 2.5 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 EDN94054.1 - 0.028 13.7 1.9 0.055 12.8 1.3 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EDN94054.1 - 0.062 12.4 1.9 0.087 11.9 1.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 EDN94054.1 - 0.44 10.4 10.0 0.56 10.0 6.3 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA PF00004.24 EDN94055.1 - 5.6e-38 130.1 0.0 1e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDN94055.1 - 5.2e-06 26.3 0.0 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EDN94055.1 - 1.5e-05 25.7 0.0 5.1e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN94055.1 - 1.9e-05 24.4 0.2 0.00035 20.3 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN94055.1 - 2.5e-05 24.4 0.1 0.00045 20.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDN94055.1 - 2.7e-05 24.1 0.0 7.8e-05 22.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN94055.1 - 3.1e-05 24.0 1.5 0.00025 21.0 0.1 2.4 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 EDN94055.1 - 4.6e-05 22.5 0.0 9.4e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EDN94055.1 - 0.00018 20.9 0.1 0.028 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN94055.1 - 0.00019 21.3 0.1 0.00067 19.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDN94055.1 - 0.00034 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EDN94055.1 - 0.00084 19.3 0.0 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDN94055.1 - 0.00086 18.5 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDN94055.1 - 0.00089 18.9 0.1 0.0095 15.5 0.0 2.6 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EDN94055.1 - 0.00097 19.2 0.0 0.0046 17.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EDN94055.1 - 0.0021 17.1 0.1 0.0056 15.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EDN94055.1 - 0.0033 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EDN94055.1 - 0.0057 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN94055.1 - 0.0063 16.8 1.2 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN94055.1 - 0.0094 15.6 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain CPT PF07931.7 EDN94055.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 EDN94055.1 - 0.017 14.6 0.0 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EDN94055.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EDN94055.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EDN94055.1 - 0.037 13.4 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EDN94055.1 - 0.044 12.7 0.1 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EDN94055.1 - 0.079 12.6 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 EDN94055.1 - 0.081 11.5 0.0 0.15 10.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EDN94055.1 - 0.085 11.9 0.0 0.79 8.7 0.0 2.2 1 1 1 2 2 2 0 KaiC Guanylate_kin PF00625.16 EDN94055.1 - 0.09 12.2 0.0 0.79 9.1 0.0 2.5 2 1 0 2 2 2 0 Guanylate kinase AAA_10 PF12846.2 EDN94055.1 - 0.11 11.9 0.2 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NB-ARC PF00931.17 EDN94055.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 EDN94055.1 - 0.13 12.1 0.8 0.24 11.2 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase AAA_11 PF13086.1 EDN94055.1 - 0.13 11.8 0.4 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain EF-1_beta_acid PF10587.4 EDN94055.1 - 7.2 6.8 12.4 8.4 6.6 1.6 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Cys_Met_Meta_PP PF01053.15 EDN94056.1 - 2.5e-137 457.2 0.0 3e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDN94056.1 - 2.5e-06 26.4 0.0 7e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDN94056.1 - 9.7e-06 24.7 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDN94056.1 - 2.1e-05 23.7 0.1 5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EDN94056.1 - 0.00011 20.7 0.1 0.00047 18.5 0.1 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EDN94056.1 - 0.0013 17.9 0.0 0.0047 16.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EDN94056.1 - 0.0014 17.3 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Herpes_gE PF02480.11 EDN94058.1 - 0.01 14.1 0.1 0.012 13.8 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EDN94058.1 - 0.013 15.1 1.3 0.018 14.6 0.9 1.2 1 0 0 1 1 1 0 Syndecan domain DUF2754 PF10953.3 EDN94058.1 - 0.11 12.5 0.2 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) CSF-1 PF05337.6 EDN94058.1 - 0.14 11.4 0.2 4.4 6.5 0.0 2.0 1 1 1 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) ORC4_C PF14629.1 EDN94059.1 - 4.2e-53 179.7 0.0 7e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD PF00628.24 EDN94059.1 - 1.5e-19 69.4 22.1 3.2e-10 39.5 4.2 2.3 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EDN94059.1 - 6.8e-18 63.7 16.1 5.8e-12 44.7 1.0 2.9 3 0 0 3 3 3 2 PHD-finger AAA_16 PF13191.1 EDN94059.1 - 3.5e-17 62.9 0.9 3.2e-16 59.8 0.6 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN94059.1 - 5.1e-08 33.1 0.1 1.6e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN94059.1 - 2.4e-07 31.0 0.0 7.5e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDN94059.1 - 9.1e-07 28.6 0.2 1e-05 25.2 0.2 2.3 1 1 0 1 1 1 1 NACHT domain ATP_bind_1 PF03029.12 EDN94059.1 - 7e-05 22.4 0.1 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EDN94059.1 - 0.00036 19.6 0.0 0.00066 18.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EDN94059.1 - 0.00043 20.0 0.1 0.00083 19.1 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EDN94059.1 - 0.00077 19.3 0.0 0.0029 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain FYVE_2 PF02318.11 EDN94059.1 - 0.00086 19.2 13.7 0.15 11.9 1.3 2.6 1 1 1 2 2 2 2 FYVE-type zinc finger AAA_29 PF13555.1 EDN94059.1 - 0.00087 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EDN94059.1 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDN94059.1 - 0.0031 18.3 0.8 0.029 15.1 0.0 2.8 2 1 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDN94059.1 - 0.0032 16.9 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 EDN94059.1 - 0.0049 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EDN94059.1 - 0.005 15.7 0.0 0.0098 14.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 EDN94059.1 - 0.011 15.3 0.0 0.035 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-PHD-like PF15446.1 EDN94059.1 - 0.011 14.9 11.7 0.058 12.6 1.0 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain ABC_tran PF00005.22 EDN94059.1 - 0.016 15.5 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EDN94059.1 - 0.02 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein C1_1 PF00130.17 EDN94059.1 - 0.022 14.4 18.6 0.036 13.7 1.2 3.3 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_19 PF13245.1 EDN94059.1 - 0.023 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EDN94059.1 - 0.024 14.1 0.1 0.08 12.3 0.1 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2791 PF10923.3 EDN94059.1 - 0.028 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_33 PF13671.1 EDN94059.1 - 0.029 14.2 0.1 0.13 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN94059.1 - 0.031 13.7 0.7 1.4 8.3 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain Miro PF08477.8 EDN94059.1 - 0.032 14.7 0.5 0.19 12.2 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein ATP-synt_ab PF00006.20 EDN94059.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 EDN94059.1 - 0.09 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain C1_3 PF07649.7 EDN94059.1 - 0.13 12.2 15.5 0.54 10.3 1.8 3.3 3 0 0 3 3 3 0 C1-like domain AT_hook PF02178.14 EDN94059.1 - 0.31 10.8 14.2 0.057 13.0 2.8 3.0 2 0 0 2 2 2 0 AT hook motif Prok-RING_1 PF14446.1 EDN94059.1 - 3.2 7.5 12.5 5 6.9 2.3 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.1 EDN94059.1 - 4.1 7.8 9.8 4.4 7.7 4.5 2.5 1 1 1 2 2 2 0 Cytochrome c3 adh_short_C2 PF13561.1 EDN94061.1 - 6.3e-10 39.2 0.1 8e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN94061.1 - 0.00092 19.1 0.4 0.0017 18.3 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase p450 PF00067.17 EDN94063.1 - 1e-11 44.0 0.2 4.9e-11 41.8 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 zf-H2C2_2 PF13465.1 EDN94066.1 - 7.8e-10 38.5 13.7 3.3e-05 23.9 1.9 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN94066.1 - 2.2e-07 30.7 13.2 0.0027 17.9 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN94066.1 - 2.7e-05 24.2 12.8 0.038 14.3 3.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2225 PF09986.4 EDN94066.1 - 0.083 12.3 0.7 0.86 9.0 0.3 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Anticodon_1 PF08264.8 EDN94067.1 - 0.14 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA HTH_44 PF14641.1 EDN94070.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 DDE_1 PF03184.14 EDN94073.1 - 4e-36 124.1 0.1 1.4e-35 122.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN94073.1 - 1.5e-11 43.8 0.2 7.8e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN94073.1 - 6.5e-08 31.9 0.0 1.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN94073.1 - 3.6e-06 26.7 0.0 1.5e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDN94073.1 - 0.013 15.2 0.0 0.085 12.7 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain CRS1_YhbY PF01985.16 EDN94073.1 - 7.3 6.6 7.5 9.3 6.3 0.1 3.2 4 0 0 4 4 4 0 CRS1 / YhbY (CRM) domain AMP-binding PF00501.23 EDN94076.1 - 1.6e-86 290.3 0.0 2.2e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN94076.1 - 0.029 15.2 0.3 0.091 13.7 0.2 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cyanate_lyase PF02560.9 EDN94076.1 - 0.093 12.2 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain ECM11 PF15463.1 EDN94077.1 - 8e-37 126.6 3.3 8e-37 126.6 2.3 3.4 4 0 0 4 4 4 1 Extracellular mutant protein 11 DUF3650 PF12368.3 EDN94077.1 - 0.33 10.4 2.0 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) PRK PF00485.13 EDN94078.1 - 7.7e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 EDN94078.1 - 9.4e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EDN94078.1 - 0.00057 18.7 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 EDN94078.1 - 0.001 19.8 0.1 0.0024 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN94078.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EDN94078.1 - 0.0051 17.1 0.3 0.017 15.3 0.0 2.0 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 EDN94078.1 - 0.0063 15.9 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EDN94078.1 - 0.0063 16.4 0.5 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EDN94078.1 - 0.0068 15.4 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Thymidylate_kin PF02223.12 EDN94078.1 - 0.0071 15.7 0.1 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase ABC_tran PF00005.22 EDN94078.1 - 0.0085 16.3 0.1 0.042 14.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.15 EDN94078.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 EDN94078.1 - 0.034 13.7 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EDN94078.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EDN94078.1 - 0.073 12.5 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EDN94079.1 - 7.2e-63 211.4 6.2 1.6e-31 109.4 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EDN94079.1 - 7.8e-32 109.2 0.0 1.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EDN94079.1 - 3.8e-31 108.1 1.4 3.6e-16 59.3 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 EDN94079.1 - 7.9e-08 32.1 0.0 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 EDN94079.1 - 0.0014 17.7 1.9 0.0044 16.0 0.1 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EDN94079.1 - 0.0022 17.4 4.1 0.013 14.8 0.1 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF4161 PF13722.1 EDN94079.1 - 0.042 14.1 0.5 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DDE_1 PF03184.14 EDN94080.1 - 0.0089 15.1 0.5 0.031 13.4 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Herpes_BLRF2 PF05812.7 EDN94080.1 - 0.096 12.5 4.2 1 9.2 0.4 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein HTH_psq PF05225.11 EDN94081.1 - 2e-09 36.8 0.0 2.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDN94081.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 NUMOD1 domain HTH_23 PF13384.1 EDN94081.1 - 0.011 15.3 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain SpoIIID PF12116.3 EDN94081.1 - 0.034 14.0 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D DUF445 PF04286.7 EDN94081.1 - 0.062 12.8 0.4 0.074 12.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Phage_CI_repr PF07022.8 EDN94081.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sec5 PF15469.1 EDN94088.1 - 1.3e-37 129.2 0.0 7.7e-37 126.7 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EDN94088.1 - 2.1e-05 24.2 0.1 0.0001 22.0 0.1 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF2642 PF10842.3 EDN94088.1 - 0.069 12.6 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Iso_dh PF00180.15 EDN94089.1 - 1e-99 333.8 0.0 1.2e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase His_Phos_2 PF00328.17 EDN94090.1 - 1.5e-52 179.0 0.0 1.8e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rot1 PF10681.4 EDN94091.1 - 2.2e-89 298.4 0.2 2.9e-89 298.0 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 EDN94092.1 - 2.1e-30 105.9 0.0 2.9e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EDN94093.1 - 6.3e-17 60.8 0.0 7.5e-17 60.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 EDN94094.1 - 5.3e-28 97.7 2.0 1.7e-27 96.1 0.6 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EDN94094.1 - 1.6e-05 24.7 0.2 0.0001 22.1 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain FANCI_S1 PF14675.1 EDN94094.1 - 0.053 12.8 0.6 4.8 6.4 0.0 2.9 2 0 0 2 2 2 0 FANCI solenoid 1 HypA PF01155.14 EDN94095.1 - 2.6 7.7 5.2 4.2 7.0 0.2 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Metallophos PF00149.23 EDN94096.1 - 1.2e-12 47.6 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN94096.1 - 0.00018 21.3 0.0 0.0005 19.9 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_1 PF00300.17 EDN94098.1 - 1.9e-12 47.5 0.0 3.9e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CCD PF07860.6 EDN94098.1 - 0.19 11.1 4.4 0.39 10.1 3.0 1.5 1 1 0 1 1 1 0 WisP family C-Terminal Region BCLP PF12304.3 EDN94101.1 - 0.087 12.2 0.2 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Beta-casein like protein RGS PF00615.14 EDN94102.1 - 9.1e-36 122.5 0.1 2.6e-35 121.0 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EDN94102.1 - 9.8e-26 89.3 0.0 2.9e-21 74.9 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS-like PF09128.6 EDN94102.1 - 0.029 13.8 0.2 0.98 8.8 0.0 2.5 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain cobW PF02492.14 EDN94103.1 - 1e-38 132.5 0.1 1.4e-38 132.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EDN94103.1 - 0.0026 16.8 0.2 0.64 8.9 0.0 2.2 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.18 EDN94103.1 - 0.0032 17.3 0.5 0.033 14.1 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDN94103.1 - 0.0065 16.6 0.1 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EDN94103.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EDN94103.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDN94103.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN94103.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EDN94103.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDN94103.1 - 0.032 14.5 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SRP54 PF00448.17 EDN94103.1 - 0.041 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EDN94103.1 - 0.059 13.1 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDN94103.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDN94103.1 - 0.076 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ORC6 PF05460.8 EDN94103.1 - 5.1 6.1 9.6 0.63 9.0 3.1 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Mob1_phocein PF03637.12 EDN94104.1 - 2.2e-24 86.0 0.1 3.7e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family DAO PF01266.19 EDN94105.1 - 1.9e-45 155.3 0.0 2.3e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN94105.1 - 1.5e-05 24.9 0.4 3.4e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDN94105.1 - 0.0007 19.7 0.2 0.0029 17.6 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN94105.1 - 0.019 13.4 0.9 0.052 12.0 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EDN94105.1 - 0.049 13.4 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EDN94105.1 - 0.09 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.20 EDN94105.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase FAD_oxidored PF12831.2 EDN94105.1 - 0.2 10.6 1.9 0.41 9.6 1.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase End3 PF12761.2 EDN94106.1 - 0.045 13.3 2.4 3 7.4 0.3 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF2046 PF09755.4 EDN94106.1 - 0.054 12.3 5.8 0.03 13.2 1.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Shugoshin_N PF07558.6 EDN94106.1 - 0.054 13.2 0.3 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIVA PF05103.8 EDN94106.1 - 0.066 13.2 3.7 0.25 11.3 0.2 2.3 2 0 0 2 2 2 0 DivIVA protein Inhibitor_Mig-6 PF11555.3 EDN94106.1 - 0.078 13.3 0.2 0.078 13.3 0.2 3.7 2 1 1 3 3 3 0 EGFR receptor inhibitor Mig-6 DUF2968 PF11180.3 EDN94106.1 - 0.082 12.2 12.2 0.33 10.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EDN94106.1 - 0.11 11.9 0.3 0.11 11.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EDN94106.1 - 0.39 10.6 4.1 3.4 7.6 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MerR-DNA-bind PF09278.6 EDN94106.1 - 0.43 11.0 10.2 0.48 10.8 0.3 2.3 2 0 0 2 2 2 0 MerR, DNA binding Fib_alpha PF08702.5 EDN94106.1 - 0.47 10.5 6.0 6.6 6.8 0.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.3 EDN94106.1 - 0.88 7.6 5.6 1.2 7.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Nsp1_C PF05064.8 EDN94106.1 - 7.3 6.2 9.0 3.5 7.2 2.6 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF2866 PF11065.3 EDN94108.1 - 0.023 14.5 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Peptidase_S41 PF03572.13 EDN94109.1 - 0.0004 19.8 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Oxidored_molyb PF00174.14 EDN94111.1 - 1.5e-49 167.6 0.0 2.4e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EDN94111.1 - 3.5e-25 88.1 1.0 6.1e-25 87.3 0.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain V_ATPase_I PF01496.14 EDN94112.1 - 0.0065 14.3 0.1 0.0078 14.1 0.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3464 PF11947.3 EDN94112.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Acyl-CoA_dh_2 PF08028.6 EDN94112.1 - 0.17 12.1 3.9 0.25 11.5 2.6 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Presenilin PF01080.12 EDN94112.1 - 0.19 10.4 0.3 0.25 10.1 0.2 1.2 1 0 0 1 1 1 0 Presenilin Bul1_N PF04425.7 EDN94112.1 - 0.23 9.9 2.3 0.31 9.5 1.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus Sporozoite_P67 PF05642.6 EDN94112.1 - 0.5 8.1 15.7 0.57 7.9 10.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3584 PF12128.3 EDN94112.1 - 6.5 3.9 15.1 11 3.2 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF883 PF05957.8 EDN94112.1 - 9.2 6.7 15.4 0.068 13.5 4.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Rick_17kDa_Anti PF05433.10 EDN94116.1 - 0.0043 16.6 5.7 0.0049 16.5 4.0 1.1 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EDN94116.1 - 0.044 13.4 5.2 0.051 13.2 3.6 1.2 1 0 0 1 1 1 0 Glycine zipper DUF1275 PF06912.6 EDN94116.1 - 0.11 11.7 1.9 0.095 11.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Bacteriocin_IIc PF10439.4 EDN94116.1 - 0.12 12.4 2.6 0.13 12.4 1.8 1.1 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EDN94116.1 - 0.37 10.3 6.5 0.47 10.0 4.5 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF2613 PF11021.3 EDN94116.1 - 0.43 10.3 4.4 0.52 10.0 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4298 PF14131.1 EDN94117.1 - 0.078 12.8 1.7 13 5.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) FKBP_C PF00254.23 EDN94118.1 - 6.6e-31 106.1 0.2 3e-30 104.0 0.0 2.2 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase FA_desaturase PF00487.19 EDN94118.1 - 0.57 9.5 1.1 0.84 9.0 0.7 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Pkinase PF00069.20 EDN94119.1 - 7.3e-50 169.5 0.0 1.1e-28 100.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94119.1 - 4.6e-22 78.3 0.0 3.2e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDN94119.1 - 0.00026 20.8 0.9 0.0015 18.2 0.4 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EDN94119.1 - 0.94 10.0 4.0 1.4 9.4 0.6 2.7 2 1 0 2 2 2 0 Protein kinase C terminal domain PTS_EIIB PF00367.15 EDN94120.1 - 0.21 10.8 0.6 0.34 10.1 0.2 1.5 2 0 0 2 2 2 0 phosphotransferase system, EIIB Fungal_trans_2 PF11951.3 EDN94122.1 - 0.00022 19.9 3.0 0.00047 18.8 2.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 EDN94123.1 - 2.5e-16 59.0 0.5 5e-16 58.1 0.2 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94123.1 - 8e-12 44.9 0.1 1.3e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN94123.1 - 2.8e-07 30.2 0.2 5.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WSC PF01822.14 EDN94124.1 - 0.012 15.5 2.5 0.012 15.5 1.8 1.1 1 0 0 1 1 1 0 WSC domain Metallothio_PEC PF02068.11 EDN94124.1 - 0.013 15.8 5.2 0.014 15.7 3.6 1.0 1 0 0 1 1 1 0 Plant PEC family metallothionein DUF3661 PF12400.3 EDN94126.1 - 3.5e-33 114.4 2.4 4.6e-33 114.0 1.7 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein DUF1980 PF09323.5 EDN94126.1 - 0.045 13.4 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) UDPGT PF00201.13 EDN94128.1 - 4.7e-11 41.9 0.0 6.9e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EDN94128.1 - 7.7e-09 35.4 0.0 2.4e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_4 PF13439.1 EDN94128.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 tRNA-synt_His PF13393.1 EDN94130.1 - 1.5e-39 135.9 0.0 3.6e-33 114.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EDN94130.1 - 1e-17 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN94130.1 - 1.1e-11 44.5 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDN94130.1 - 8.8e-05 21.4 0.0 0.002 16.9 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Sec1 PF00995.18 EDN94131.1 - 1.3e-138 463.1 0.0 1.5e-138 462.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SIS PF01380.17 EDN94131.1 - 0.12 12.0 0.1 8.1 6.0 0.0 3.1 3 0 0 3 3 3 0 SIS domain Amino_oxidase PF01593.19 EDN94132.1 - 3.5e-86 290.0 0.0 4.8e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EDN94132.1 - 5.5e-10 39.2 0.1 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EDN94132.1 - 9.6e-08 31.9 0.1 2.4e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EDN94132.1 - 8.5e-07 29.1 3.4 8.5e-07 29.1 2.3 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN94132.1 - 1.1e-06 28.8 4.4 2.6e-06 27.7 3.1 1.7 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.19 EDN94132.1 - 0.081 11.8 0.0 0.21 10.4 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase NUMOD3 PF07460.6 EDN94132.1 - 0.19 11.6 0.9 0.43 10.5 0.6 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) F_actin_cap_B PF01115.12 EDN94133.1 - 6.8e-107 356.1 0.0 7.8e-107 355.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit SIP1 PF04938.7 EDN94135.1 - 0.13 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Epimerase PF01370.16 EDN94137.1 - 3e-18 66.1 0.0 4.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EDN94137.1 - 4.4e-11 42.2 0.0 6.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EDN94137.1 - 6e-05 23.0 0.0 0.00024 21.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EDN94137.1 - 0.00015 20.5 0.0 0.00037 19.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN94137.1 - 0.0031 17.5 0.2 0.023 14.6 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EDN94137.1 - 0.0053 15.7 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EDN94137.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein ATG22 PF11700.3 EDN94138.1 - 1.1e-206 686.9 11.3 1.3e-206 686.7 7.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EDN94138.1 - 6.2e-06 25.1 48.2 0.0001 21.1 3.7 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Med14 PF08638.6 EDN94139.1 - 2e-58 196.9 0.9 4.5e-58 195.7 0.6 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 UCH PF00443.24 EDN94140.1 - 2.7e-19 69.3 0.0 4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN94140.1 - 6.4e-06 25.8 0.3 0.0016 17.9 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2222 PF09984.4 EDN94140.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Tachykinin PF02202.11 EDN94140.1 - 9.6 6.2 8.2 5.5 6.9 0.0 3.6 4 0 0 4 4 4 0 Tachykinin family CDC27 PF09507.5 EDN94141.1 - 0.15 11.2 23.2 0.22 10.6 16.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3987 PF13148.1 EDN94141.1 - 2.2 6.7 10.3 11 4.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Yos1 PF08571.5 EDN94142.1 - 6.7e-26 90.2 1.0 7.5e-26 90.0 0.7 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EDN94143.1 - 2.4e-39 135.5 16.7 2.9e-39 135.2 11.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Consortin_C PF15281.1 EDN94144.1 - 0.31 10.5 1.8 0.32 10.4 1.3 1.0 1 0 0 1 1 1 0 Consortin C-terminus Apis_Csd PF11671.3 EDN94144.1 - 2.1 8.1 6.0 2.3 8.0 4.1 1.0 1 0 0 1 1 1 0 Complementary sex determiner protein Cir_N PF10197.4 EDN94144.1 - 4.5 7.3 17.9 6.3 6.9 12.4 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Atrophin-1 PF03154.10 EDN94144.1 - 5.5 5.0 14.5 5.5 5.0 10.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family ATP-synt PF00231.14 EDN94147.1 - 1.9e-70 237.5 5.0 2.2e-70 237.3 3.5 1.0 1 0 0 1 1 1 1 ATP synthase Beta-Casp PF10996.3 EDN94147.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Beta-Casp domain Topoisom_I_N PF02919.10 EDN94149.1 - 3.5e-95 317.3 0.9 3.5e-95 317.3 0.6 3.4 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EDN94149.1 - 2.8e-85 285.1 5.3 2.8e-85 285.1 3.7 2.8 2 1 1 3 3 3 2 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EDN94149.1 - 1.3e-30 104.8 0.2 4.6e-30 103.0 0.1 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain FAD_binding_3 PF01494.14 EDN94150.1 - 1.1e-24 87.1 0.2 1.7e-23 83.2 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN94150.1 - 1.2e-05 24.4 0.1 0.029 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN94150.1 - 0.0031 16.4 0.0 0.0083 15.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EDN94150.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN94150.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN94150.1 - 0.022 13.6 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EDN94150.1 - 0.023 13.3 0.0 3.8 6.0 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.5 EDN94150.1 - 0.024 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase UQ_con PF00179.21 EDN94151.1 - 4e-27 94.3 0.1 4.7e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN94151.1 - 1.1e-07 31.6 0.0 2.6e-06 27.2 0.0 2.0 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EDN94151.1 - 9.6e-05 22.2 0.5 0.00012 21.8 0.3 1.4 1 1 0 1 1 1 1 RWD domain Pkinase PF00069.20 EDN94152.1 - 1.2e-62 211.4 0.0 1.8e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94152.1 - 5.3e-26 91.2 0.0 8.7e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN94152.1 - 5.4e-06 25.5 0.0 7.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDN94152.1 - 0.0038 16.5 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RTC4 PF14474.1 EDN94154.1 - 2.6e-35 121.0 0.0 4.9e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 EDN94155.1 - 2e-35 122.3 13.2 1.3e-17 63.6 6.7 2.7 2 1 0 2 2 2 2 Dynamitin DUF2205 PF10224.4 EDN94155.1 - 0.0055 16.2 9.6 7.3 6.2 0.5 4.3 4 0 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) Laminin_II PF06009.7 EDN94155.1 - 0.013 15.2 11.1 0.037 13.7 0.4 3.6 2 1 2 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.4 EDN94155.1 - 0.02 15.0 10.4 5.3 7.2 0.0 4.3 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.7 EDN94155.1 - 0.027 13.8 13.4 0.45 9.8 0.1 3.4 3 0 0 3 3 3 0 PspA/IM30 family DivIC PF04977.10 EDN94155.1 - 0.029 13.8 12.2 0.88 9.0 0.9 3.6 3 0 0 3 3 3 0 Septum formation initiator Tropomyosin_1 PF12718.2 EDN94155.1 - 0.04 13.7 14.8 1.4 8.7 0.3 3.4 3 0 0 3 3 3 0 Tropomyosin like KxDL PF10241.4 EDN94155.1 - 0.058 13.2 0.3 18 5.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein IncA PF04156.9 EDN94155.1 - 0.07 12.7 8.8 4.9 6.6 0.5 3.3 3 0 0 3 3 3 0 IncA protein Effector_1 PF04518.7 EDN94155.1 - 0.11 11.4 1.1 0.13 11.2 0.1 1.5 2 0 0 2 2 2 0 Effector from type III secretion system SYF2 PF08231.7 EDN94155.1 - 0.13 12.3 8.2 0.037 14.1 1.2 2.7 3 0 0 3 3 3 0 SYF2 splicing factor COG2 PF06148.6 EDN94155.1 - 0.19 11.5 5.7 6 6.7 0.1 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.6 EDN94155.1 - 0.22 11.2 9.4 2.7 7.7 0.5 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4446 PF14584.1 EDN94155.1 - 0.24 11.2 6.2 2.6 7.8 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF948 PF06103.6 EDN94155.1 - 0.25 11.2 4.5 11 5.9 0.2 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sipho_Gp157 PF05565.6 EDN94155.1 - 0.4 10.2 0.0 0.4 10.2 0.0 2.8 3 0 0 3 3 3 0 Siphovirus Gp157 DUF1192 PF06698.6 EDN94155.1 - 0.5 10.2 10.7 2.8 7.8 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Mnd1 PF03962.10 EDN94155.1 - 0.63 9.6 11.8 0.59 9.7 1.0 3.3 3 0 0 3 3 3 0 Mnd1 family FH2 PF02181.18 EDN94155.1 - 0.65 8.8 5.5 4.9 5.9 0.1 3.0 3 0 0 3 3 3 0 Formin Homology 2 Domain XhlA PF10779.4 EDN94155.1 - 1 9.3 11.0 3.1 7.7 0.8 3.4 3 0 0 3 3 3 0 Haemolysin XhlA zf-C4H2 PF10146.4 EDN94155.1 - 1 9.3 4.4 16 5.4 0.4 2.8 2 1 0 2 2 2 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.7 EDN94155.1 - 1.1 9.0 13.6 1.3 8.8 0.4 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.1 EDN94155.1 - 5 7.4 8.2 3.2 8.1 0.3 3.6 3 2 1 4 4 4 0 Snapin/Pallidin CENP-Q PF13094.1 EDN94155.1 - 7.1 6.6 16.3 6.8 6.6 3.7 3.0 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lge1 PF11488.3 EDN94155.1 - 8 6.7 10.3 10 6.4 0.8 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Viral_P18 PF04521.8 EDN94155.1 - 10 5.6 9.3 24 4.3 0.3 3.3 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein MFS_2 PF13347.1 EDN94156.1 - 1.9e-09 36.4 7.5 1.9e-09 36.4 5.2 2.9 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EDN94156.1 - 0.039 13.7 2.0 0.66 9.8 0.0 3.0 2 0 0 2 2 2 0 MFS_1 like family Aminotran_1_2 PF00155.16 EDN94162.1 - 3e-16 59.3 0.0 3.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDN94162.1 - 0.0034 15.9 0.0 0.0076 14.8 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase p450 PF00067.17 EDN94164.1 - 1.4e-64 218.3 0.0 1.9e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 EDN94165.1 - 1e-82 278.1 0.0 1.3e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EDN94165.1 - 1.4e-22 80.6 0.1 2.5e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EDN94165.1 - 1.8e-08 34.9 0.4 2.7e-07 31.1 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 zf-CCCH_2 PF14608.1 EDN94167.1 - 6e-11 41.9 48.6 9.1e-06 25.4 5.0 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EDN94167.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 EDN94168.1 - 2.5e-19 69.7 0.1 7.7e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDN94168.1 - 0.00083 19.3 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-RING_2 PF13639.1 EDN94169.1 - 6.4e-06 25.9 3.4 1.1e-05 25.2 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN94169.1 - 0.00074 19.1 0.6 0.0013 18.3 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN94169.1 - 0.0092 15.6 1.1 0.015 15.0 0.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN94169.1 - 0.027 14.1 1.1 0.048 13.3 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN94169.1 - 0.031 14.3 2.4 0.058 13.4 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDN94169.1 - 0.97 9.1 3.9 1.7 8.3 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_16 PF00722.16 EDN94170.1 - 1.3e-39 135.3 1.1 2.1e-39 134.7 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CRAL_TRIO PF00650.15 EDN94171.1 - 6.7e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN94171.1 - 0.024 14.7 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain PDDEXK_4 PF14281.1 EDN94171.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily USP7_ICP0_bdg PF12436.3 EDN94173.1 - 2.7e-79 265.9 0.1 1.3e-77 260.4 0.0 3.2 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EDN94173.1 - 1.6e-54 184.8 3.8 3e-54 183.9 2.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EMP24_GP25L PF01105.19 EDN94173.1 - 1e-45 155.7 3.7 1.9e-45 154.8 2.6 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_C2 PF14533.1 EDN94173.1 - 3e-42 144.4 5.8 6.6e-40 136.8 0.3 4.2 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EDN94173.1 - 1.9e-29 103.0 0.2 9.8e-29 100.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EDN94173.1 - 7.2e-07 29.4 3.2 8e-07 29.3 0.1 2.8 3 0 0 3 3 3 1 MATH domain YukD PF08817.5 EDN94173.1 - 0.11 13.0 0.0 38 4.9 0.0 3.4 2 1 1 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD SKIP_SNW PF02731.10 EDN94174.1 - 5.6e-68 227.3 5.5 5.6e-68 227.3 3.8 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SR-25 PF10500.4 EDN94174.1 - 0.11 11.9 23.9 0.23 10.8 16.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 EDN94174.1 - 4.9 6.8 10.0 12 5.5 6.9 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_hydro_16 PF00722.16 EDN94175.1 - 4e-09 36.0 0.1 9.7e-09 34.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 OppC_N PF12911.2 EDN94175.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4307 PF14155.1 EDN94175.1 - 0.12 12.1 2.9 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Tim17 PF02466.14 EDN94176.1 - 3.4e-51 172.6 6.0 4e-51 172.3 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EDN94176.1 - 0.23 11.1 7.8 0.21 11.2 1.5 2.5 2 0 0 2 2 2 0 Glycine zipper ABA_WDS PF02496.11 EDN94176.1 - 1.1 9.5 3.7 1.7 8.8 1.2 2.3 2 1 0 2 2 2 0 ABA/WDS induced protein EmrE PF13536.1 EDN94177.1 - 0.00072 19.7 0.5 0.0012 19.0 0.3 1.4 1 0 0 1 1 1 1 Multidrug resistance efflux transporter CHDCT2 PF08074.6 EDN94177.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF4243 PF14027.1 EDN94178.1 - 1.7e-106 356.4 0.4 2.2e-106 356.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1910 PF08928.5 EDN94178.1 - 0.054 13.5 0.2 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) PhoD PF09423.5 EDN94179.1 - 4.6e-62 210.0 0.0 5.8e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase ORC6 PF05460.8 EDN94180.1 - 0.0082 15.2 0.4 0.016 14.3 0.3 1.5 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) CENP-N PF05238.8 EDN94180.1 - 0.014 14.4 0.5 0.02 13.9 0.4 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Prefoldin_2 PF01920.15 EDN94182.1 - 2.5e-23 81.8 4.2 3.1e-23 81.5 2.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 EDN94182.1 - 0.088 12.2 2.0 0.11 11.9 1.4 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_23 PF13476.1 EDN94182.1 - 0.68 10.2 4.9 0.82 9.9 3.4 1.1 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EDN94183.1 - 2.1e-40 138.5 35.9 2.1e-40 138.5 24.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN94183.1 - 7.8e-10 37.9 20.9 2.5e-09 36.2 14.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1673 PF07895.6 EDN94183.1 - 1.8 8.0 7.5 0.86 9.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) 2OG-FeII_Oxy PF03171.15 EDN94185.1 - 3.6e-13 49.6 0.0 5.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN94185.1 - 0.0024 18.3 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal APC10 PF03256.11 EDN94186.1 - 2e-48 164.6 0.0 2.8e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EDN94186.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain SDA1 PF05285.7 EDN94186.1 - 0.28 10.4 4.4 0.38 9.9 3.0 1.2 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 EDN94186.1 - 0.28 11.2 5.5 0.41 10.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 EDN94186.1 - 7.6 4.8 8.0 11 4.3 5.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF3824 PF12868.2 EDN94187.1 - 0.1 13.4 1.9 0.12 13.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Viral_P18 PF04521.8 EDN94187.1 - 0.11 11.8 1.4 0.15 11.4 0.4 1.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Unstab_antitox PF09720.5 EDN94187.1 - 0.31 10.7 2.2 0.56 9.9 0.3 2.1 1 1 1 2 2 2 0 Putative addiction module component ATG27 PF09451.5 EDN94189.1 - 1.1e-66 224.8 0.0 1.3e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EDN94189.1 - 8.1e-05 22.4 0.0 0.018 14.8 0.0 2.5 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat MFS_1 PF07690.11 EDN94192.1 - 4.8e-39 134.0 19.4 4.8e-39 134.0 13.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN94192.1 - 3.9e-11 42.2 12.5 5.2e-11 41.7 8.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter NAD_binding_4 PF07993.7 EDN94193.1 - 1.1e-36 125.9 0.1 1.9e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN94193.1 - 3.3e-33 114.6 0.0 7.7e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 EDN94193.1 - 6.3e-14 51.4 0.1 1.3e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.16 EDN94193.1 - 1.9e-13 50.4 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN94193.1 - 1.6e-08 34.6 0.1 4.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EDN94193.1 - 3.2e-07 29.3 0.0 5.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EDN94193.1 - 8.1e-05 22.3 0.1 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EDN94193.1 - 0.00076 19.4 0.2 0.0024 17.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EDN94193.1 - 0.042 12.7 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 EDN94193.1 - 0.06 13.8 0.1 6.3 7.3 0.0 3.0 3 0 0 3 3 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gp58 PF07902.6 EDN94193.1 - 0.082 11.1 0.9 0.11 10.6 0.1 1.5 2 0 0 2 2 2 0 gp58-like protein MR_MLE_C PF13378.1 EDN94194.1 - 3.3e-35 120.4 0.1 7.8e-35 119.2 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EDN94194.1 - 1.4e-14 54.1 0.0 3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EDN94194.1 - 1.2e-11 44.9 0.0 3.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Aldo_ket_red PF00248.16 EDN94195.1 - 4.5e-57 193.0 0.0 5.7e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DHDPS PF00701.17 EDN94196.1 - 9.8e-22 76.8 0.0 1.1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pec_lyase_C PF00544.14 EDN94198.1 - 8.2e-18 64.5 5.4 1.5e-17 63.7 3.8 1.4 1 0 0 1 1 1 1 Pectate lyase Baculo_LEF5 PF04838.7 EDN94198.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 DEAD PF00270.24 EDN94202.1 - 2.4e-32 111.7 0.0 1.3e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94202.1 - 2.3e-21 75.4 0.0 5.5e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN94202.1 - 6.2e-05 22.9 4.3 0.0001 22.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SR-25 PF10500.4 EDN94202.1 - 0.00016 21.2 16.5 0.00016 21.2 11.5 3.3 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 EDN94202.1 - 0.003 15.5 4.7 0.003 15.5 3.2 2.1 2 0 0 2 2 2 1 Nop14-like family PapG_C PF03628.8 EDN94202.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 PapG chaperone-binding domain SAPS PF04499.10 EDN94202.1 - 1.6 7.2 12.7 2.5 6.6 0.4 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EDN94202.1 - 7.4 4.4 36.7 0.025 12.6 4.5 2.2 2 0 0 2 2 2 0 CDC45-like protein PIGA PF08288.7 EDN94203.1 - 2.4e-46 156.0 3.7 4.6e-46 155.1 1.1 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EDN94203.1 - 1.2e-29 102.9 0.0 1.8e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN94203.1 - 4.7e-18 65.6 0.1 7.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EDN94203.1 - 2.6e-10 40.6 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EDN94203.1 - 1.6e-09 37.7 1.0 9.2e-09 35.2 0.7 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EDN94203.1 - 0.00021 21.5 0.0 0.00052 20.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EDN94203.1 - 0.014 15.2 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Peroxidase_2 PF01328.12 EDN94205.1 - 2.8e-13 49.2 0.2 5.4e-13 48.2 0.1 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 DUF3431 PF11913.3 EDN94206.1 - 8.9e-14 51.4 0.0 5.1e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Pkinase PF00069.20 EDN94211.1 - 3.1e-16 59.3 0.1 6.4e-16 58.2 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN94211.1 - 0.00075 18.6 0.3 0.0012 17.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Extensin-like_C PF06904.7 EDN94212.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Extensin-like protein C-terminus Acetyltransf_1 PF00583.19 EDN94213.1 - 6.8e-05 22.8 0.0 0.00016 21.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EDN94213.1 - 0.074 13.6 0.0 1.1 9.8 0.0 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN94213.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HSP70 PF00012.15 EDN94214.1 - 2.9e-58 197.2 8.3 5.5e-55 186.4 0.1 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EDN94214.1 - 0.00071 18.2 0.0 0.0017 17.0 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein p450 PF00067.17 EDN94215.1 - 1.4e-49 168.9 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4037 PF13228.1 EDN94215.1 - 0.076 13.2 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) Fungal_trans PF04082.13 EDN94217.1 - 6e-12 44.9 0.1 9.9e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN94217.1 - 0.0024 17.7 9.4 0.0041 17.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Parathyroid PF01279.12 EDN94217.1 - 0.058 14.0 1.0 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 Parathyroid hormone family HATPase_c PF02518.21 EDN94218.1 - 2.8e-23 81.7 0.7 1.5e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN94218.1 - 1e-21 77.0 0.0 5.3e-18 65.0 0.1 3.5 2 1 0 2 2 2 2 Response regulator receiver domain GAF PF01590.21 EDN94218.1 - 2e-05 24.7 0.0 0.00089 19.4 0.0 2.7 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 EDN94218.1 - 0.025 14.6 0.0 1.2 9.2 0.0 3.2 3 1 0 3 3 3 0 GAF domain Glyco_hydro_11 PF00457.12 EDN94219.1 - 8.4e-79 263.1 21.3 9.7e-79 262.9 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Cerato-platanin PF07249.7 EDN94223.1 - 4.4e-53 178.3 1.7 5.1e-53 178.1 1.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EDN94223.1 - 0.049 13.7 1.3 0.078 13.0 0.9 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 45 DUF1966 PF09260.6 EDN94223.1 - 0.12 12.4 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) BBP1_N PF15271.1 EDN94226.1 - 0.16 12.3 4.9 1.1 9.5 0.6 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein Alpha-amylase PF00128.19 EDN94228.1 - 2.2e-30 106.1 3.3 6.3e-30 104.6 2.3 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EDN94228.1 - 3.1e-07 28.6 2.8 0.042 11.6 0.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EDN94228.1 - 0.00039 20.2 0.2 0.00085 19.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Kin17_mid PF10357.4 EDN94228.1 - 0.088 12.4 1.1 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein HTH_Tnp_Tc5 PF03221.11 EDN94230.1 - 0.076 12.8 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RVT_1 PF00078.22 EDN94233.1 - 1.5e-29 102.9 0.0 2.3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GSH_synth_ATP PF03917.12 EDN94233.1 - 0.053 12.0 0.0 0.092 11.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain GST_C PF00043.20 EDN94235.1 - 1e-14 54.2 0.0 1.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN94235.1 - 3.6e-10 39.5 0.0 6.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN94235.1 - 1.7e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phostensin_N PF13916.1 EDN94235.1 - 0.0018 18.1 0.2 0.0036 17.2 0.1 1.5 1 0 0 1 1 1 1 PP1-regulatory protein, Phostensin N-terminal GST_N PF02798.15 EDN94235.1 - 0.0094 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF953 PF06110.6 EDN94236.1 - 8.9e-15 54.1 0.1 1e-14 53.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EDN94236.1 - 0.12 12.0 0.1 0.51 10.0 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin HMG_box PF00505.14 EDN94236.1 - 0.15 12.3 1.0 8.4 6.7 0.0 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box Fis1_TPR_C PF14853.1 EDN94237.1 - 0.4 10.6 2.8 3.1 7.7 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TelA PF05816.6 EDN94238.1 - 0.051 12.2 1.6 0.14 10.8 1.1 1.6 1 1 0 1 1 1 0 Toxic anion resistance protein (TelA) polyprenyl_synt PF00348.12 EDN94240.1 - 1.3e-59 201.1 0.0 1.5e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 EDN94241.1 - 7.7e-102 339.8 0.0 8.7e-102 339.6 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component RNase_H PF00075.19 EDN94242.1 - 2.4e-13 50.5 0.1 8e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 RNase H TMEM154 PF15102.1 EDN94242.1 - 0.00011 21.8 2.1 0.00027 20.6 1.5 1.6 1 0 0 1 1 1 1 TMEM154 protein family HTH_psq PF05225.11 EDN94242.1 - 0.034 13.6 0.5 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Plasmodium_Vir PF05795.6 EDN94242.1 - 0.037 13.2 5.5 0.069 12.3 3.8 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein STE2 PF02116.10 EDN94242.1 - 0.039 13.0 0.3 0.061 12.3 0.2 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR SSP160 PF06933.6 EDN94242.1 - 0.046 11.7 16.9 0.066 11.1 11.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF912 PF06024.7 EDN94242.1 - 0.073 13.1 0.9 0.3 11.1 0.6 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HTH_Tnp_Tc5 PF03221.11 EDN94242.1 - 0.091 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain SKG6 PF08693.5 EDN94242.1 - 0.12 11.7 0.4 2.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain WD40 PF00400.27 EDN94244.1 - 1.6e-186 598.4 42.4 1.5e-15 56.3 0.1 12.4 12 0 0 12 12 12 12 WD domain, G-beta repeat PD40 PF07676.7 EDN94244.1 - 1.5e-13 50.0 15.8 34 4.2 0.0 12.2 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 EDN94244.1 - 5.1e-13 49.0 2.1 6.8e-07 29.0 0.2 2.4 1 1 1 2 2 2 2 NACHT domain DUF1652 PF07865.6 EDN94244.1 - 3.4e-10 39.3 0.0 62 3.2 0.0 10.0 11 0 0 11 11 11 0 Protein of unknown function (DUF1652) DUF1258 PF06869.7 EDN94244.1 - 1.3e-08 34.2 9.7 0.57 9.2 0.0 9.4 2 1 10 12 12 12 1 Protein of unknown function (DUF1258) Nbas_N PF15492.1 EDN94244.1 - 2.7e-05 23.4 13.0 1.3 8.0 0.0 8.1 1 1 10 11 11 11 2 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 EDN94244.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EDN94244.1 - 0.19 10.8 0.0 0.5 9.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4282 PF14110.1 EDN94247.1 - 0.0019 18.3 0.7 0.0033 17.5 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) TMC PF07810.8 EDN94247.1 - 0.022 15.1 2.0 0.027 14.9 0.2 2.0 2 0 0 2 2 2 0 TMC domain zf-DHHC PF01529.15 EDN94247.1 - 0.023 14.0 0.6 0.043 13.2 0.4 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Kei1 PF08552.6 EDN94247.1 - 0.1 12.2 1.3 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SdpI PF13630.1 EDN94247.1 - 0.13 11.9 2.9 0.31 10.7 2.0 1.6 1 1 0 1 1 1 0 SdpI/YhfL protein family PTR2 PF00854.16 EDN94248.1 - 2e-57 194.6 12.3 3.4e-57 193.9 8.5 1.4 1 0 0 1 1 1 1 POT family Ring_hydroxyl_A PF00848.14 EDN94249.1 - 0.031 13.9 0.2 0.092 12.3 0.2 1.7 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Sugar_tr PF00083.19 EDN94252.1 - 8.8e-89 298.1 21.2 8.8e-89 298.1 14.7 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN94252.1 - 8.1e-13 47.8 39.6 8.3e-09 34.6 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 EDN94252.1 - 0.009 14.9 0.6 0.023 13.6 0.4 1.6 1 0 0 1 1 1 1 UAA transporter family DUF3328 PF11807.3 EDN94255.1 - 3.7e-14 52.9 0.1 5.5e-14 52.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) AflR PF08493.5 EDN94257.1 - 1.1 8.2 10.3 0.27 10.2 4.0 2.1 2 0 0 2 2 2 0 Aflatoxin regulatory protein Zn_clus PF00172.13 EDN94258.1 - 4.8e-07 29.5 7.6 9.7e-07 28.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1560 PF07597.6 EDN94258.1 - 0.051 13.5 0.9 0.1 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) ADH_N PF08240.7 EDN94262.1 - 1.9e-27 95.1 1.6 1.9e-27 95.1 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN94262.1 - 7.7e-20 70.7 0.1 1.4e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN94262.1 - 0.001 19.9 0.0 0.0025 18.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EDN94262.1 - 0.0032 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EDN94262.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EDN94262.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1188 PF06690.6 EDN94262.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.9 EDN94262.1 - 0.057 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EDN94262.1 - 0.074 13.4 0.2 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CbiJ PF02571.9 EDN94263.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK DUF4345 PF14248.1 EDN94264.1 - 0.043 13.2 10.7 0.076 12.4 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) EmrE PF13536.1 EDN94264.1 - 2.9 8.1 8.2 13 6.0 1.5 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter DDE_1 PF03184.14 EDN94266.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN94266.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN94266.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN94266.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN94266.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle SKG6 PF08693.5 EDN94267.1 - 1e-09 37.4 1.8 1e-09 37.4 1.2 3.0 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EDN94267.1 - 0.22 11.1 1.7 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Rifin/stevor family Neil1-DNA_bind PF09292.5 EDN94268.1 - 0.098 12.4 0.1 9.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind zf-C4_Topoisom PF01396.14 EDN94269.1 - 0.00012 21.4 1.5 0.00062 19.2 0.0 2.3 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Peptidase_S49_N PF08496.5 EDN94269.1 - 0.1 12.3 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_12 PF13087.1 EDN94270.1 - 1.8e-27 96.0 0.0 3.8e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDN94270.1 - 9.1e-21 74.5 0.0 2.5e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDN94270.1 - 0.00015 21.3 0.7 0.00092 18.8 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDN94270.1 - 0.00043 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDN94270.1 - 0.016 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sdh5 PF03937.11 EDN94271.1 - 4.7e-24 83.8 0.2 1.2e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase FtsL PF04999.8 EDN94273.1 - 0.29 10.8 2.2 0.55 9.9 1.5 1.4 1 0 0 1 1 1 0 Cell division protein FtsL DUF3433 PF11915.3 EDN94275.1 - 9.2e-43 144.3 14.7 7.8e-26 90.0 0.7 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) 4HBT PF03061.17 EDN94276.1 - 0.0022 18.0 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DEAD PF00270.24 EDN94277.1 - 1.3e-41 141.9 0.0 2.4e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94277.1 - 2.8e-22 78.3 0.0 8.2e-22 76.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDN94277.1 - 3.5e-21 74.5 0.3 6.7e-21 73.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RNA_pol_Rpb1_5 PF04998.12 EDN94277.1 - 0.83 8.8 6.8 0.78 8.9 3.7 1.7 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Daxx PF03344.10 EDN94277.1 - 1 7.8 24.7 1.3 7.4 17.1 1.1 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 EDN94277.1 - 1 7.8 9.8 1.6 7.2 6.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.6 EDN94277.1 - 1 9.1 20.0 2 8.2 13.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 EDN94277.1 - 3.9 6.6 14.2 17 4.5 8.4 2.2 2 0 0 2 2 2 0 NOA36 protein Merozoite_SPAM PF07133.6 EDN94277.1 - 5.4 6.8 31.5 12 5.7 21.8 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Astro_capsid PF03115.9 EDN94277.1 - 6.7 4.8 7.4 9.4 4.3 5.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Spore_coat_CotO PF14153.1 EDN94277.1 - 7.6 5.9 22.9 13 5.1 15.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO COPI_C PF06957.6 EDN94277.1 - 8.3 4.8 12.3 15 3.9 8.5 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Vfa1 PF08432.5 EDN94277.1 - 8.4 6.3 19.6 14 5.6 13.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRP PF06011.7 EDN94278.1 - 2.6e-158 527.1 31.2 3.1e-158 526.9 21.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDN94278.1 - 6.8e-42 142.8 1.0 1.1e-41 142.1 0.7 1.4 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EDN94278.1 - 0.0027 17.0 0.0 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycoprotein UL132 VirB3 PF05101.8 EDN94278.1 - 0.033 14.1 7.6 0.48 10.4 1.2 3.2 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DDE_1 PF03184.14 EDN94280.1 - 2.5e-29 101.9 0.0 4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN94280.1 - 2.3e-17 62.5 0.0 1.7e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN94280.1 - 5.9e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN94280.1 - 6e-05 22.5 0.4 0.00016 21.1 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF3400 PF11880.3 EDN94280.1 - 0.034 13.3 0.1 1.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3400) UPF0180 PF03698.8 EDN94280.1 - 0.068 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) HTH_28 PF13518.1 EDN94280.1 - 0.087 12.8 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Doppel PF11466.3 EDN94281.1 - 4.2 7.0 5.6 2.9 7.5 0.2 2.3 2 1 0 2 2 2 0 Prion-like protein Doppel MFS_1 PF07690.11 EDN94282.1 - 5e-28 97.8 28.1 5e-28 97.8 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AIP3 PF03915.8 EDN94284.1 - 1.7e-165 551.0 16.3 2.6e-165 550.4 11.3 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 FliL PF03748.9 EDN94284.1 - 0.02 14.8 0.1 0.12 12.3 0.1 2.4 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Lectin_N PF03954.9 EDN94284.1 - 0.03 13.6 0.4 0.03 13.6 0.3 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain LsmAD PF06741.8 EDN94286.1 - 1.5e-17 63.4 2.3 1.5e-17 63.4 1.6 1.7 2 0 0 2 2 2 1 LsmAD domain DNA_binding_1 PF01035.15 EDN94287.1 - 2.5e-24 84.8 0.0 3.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PPI_Ypi1 PF07491.6 EDN94289.1 - 7.1e-26 89.6 0.3 1.6e-25 88.4 0.2 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.7 EDN94289.1 - 0.34 10.5 2.6 0.5 10.0 1.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EDN94289.1 - 0.57 8.1 3.0 0.83 7.6 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EDN94289.1 - 4.2 5.5 6.7 4.9 5.3 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Pectinesterase PF01095.14 EDN94292.1 - 1.9e-40 138.2 8.0 2.6e-40 137.8 5.6 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.12 EDN94294.1 - 2.1e-104 349.0 20.9 2.4e-104 348.8 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AcetylCoA_hyd_C PF13336.1 EDN94294.1 - 0.071 12.7 4.2 0.54 9.9 0.4 2.5 1 1 1 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Beta_helix PF13229.1 EDN94294.1 - 0.3 10.8 34.2 5.4 6.7 23.7 2.8 1 1 0 1 1 1 0 Right handed beta helix region DUF1279 PF06916.8 EDN94295.1 - 1.6e-32 111.6 0.0 3.5e-32 110.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Aminotran_5 PF00266.14 EDN94296.1 - 4.9e-32 111.0 0.0 6.2e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDN94296.1 - 0.00011 20.6 0.0 0.00018 19.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 EDN94296.1 - 0.0012 18.7 0.3 0.033 14.0 0.0 2.6 2 1 0 2 2 2 1 B12 binding domain Beta_elim_lyase PF01212.16 EDN94296.1 - 0.0045 16.1 0.0 0.0059 15.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase CRM1_C PF08767.6 EDN94298.1 - 5.8e-135 449.2 1.6 5.8e-135 449.2 1.1 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EDN94298.1 - 3.7e-22 78.8 4.4 1.7e-21 76.6 0.9 3.7 3 1 1 4 4 4 1 Exportin 1-like protein DUF3385 PF11865.3 EDN94298.1 - 0.035 14.0 4.2 0.11 12.4 0.0 3.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 EDN94298.1 - 0.064 13.6 0.9 1.9 8.9 0.0 3.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region C8 PF08742.6 EDN94298.1 - 0.13 12.5 0.8 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 C8 domain Phytase-like PF13449.1 EDN94299.1 - 3.7e-29 102.0 0.0 5.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase CN_hydrolase PF00795.17 EDN94301.1 - 9.1e-32 109.9 0.0 1.2e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Vfa1 PF08432.5 EDN94303.1 - 0.08 12.9 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fungal_trans PF04082.13 EDN94304.1 - 0.014 14.3 0.2 0.014 14.3 0.1 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain SurE PF01975.12 EDN94305.1 - 5.7e-35 120.4 1.3 8.2e-35 119.8 0.9 1.2 1 0 0 1 1 1 1 Survival protein SurE HET PF06985.6 EDN94306.1 - 0.054 13.6 0.5 0.2 11.8 0.0 2.1 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) TBPIP_N PF15517.1 EDN94307.1 - 0.029 13.9 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 TBP-interacting protein N-terminus YsaB PF13983.1 EDN94311.1 - 0.05 13.7 0.1 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein Ecl1 PF12855.2 EDN94312.1 - 1.2e-08 34.0 1.3 2.2e-08 33.2 0.9 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF3519 PF12033.3 EDN94312.1 - 0.1 12.8 0.8 0.14 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Metallothio_Pro PF02069.11 EDN94312.1 - 0.15 11.9 1.1 0.27 11.0 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein PPV_E1_N PF00524.13 EDN94313.1 - 0.067 13.4 1.3 0.075 13.2 0.9 1.1 1 0 0 1 1 1 0 E1 Protein, N terminal domain DUF3181 PF11378.3 EDN94314.1 - 0.096 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) P_proprotein PF01483.15 EDN94318.1 - 0.16 11.7 6.3 11 5.8 0.0 3.4 1 1 1 2 2 2 0 Proprotein convertase P-domain ADK PF00406.17 EDN94319.1 - 1.4e-18 67.2 0.1 1.5e-08 34.6 0.0 2.5 2 1 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 EDN94319.1 - 0.001 19.3 0.0 0.0088 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF2767 PF10965.3 EDN94319.1 - 0.0047 16.7 0.5 0.42 10.4 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2767) AAA_17 PF13207.1 EDN94319.1 - 0.046 14.5 0.0 0.079 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NmrA PF05368.8 EDN94320.1 - 9.9e-24 83.8 0.0 1.3e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EDN94320.1 - 0.009 15.9 0.2 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDN94320.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EDN94320.1 - 0.034 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 EDN94320.1 - 0.058 12.8 0.1 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RVT_2 PF07727.9 EDN94321.1 - 1.6e-70 236.9 0.0 2.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN94321.1 - 2.5e-11 43.7 0.0 8.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN94321.1 - 2e-08 33.7 0.0 6.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN94321.1 - 2.8e-05 23.8 0.4 6.2e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN94321.1 - 0.00037 20.0 0.6 0.00037 20.0 0.4 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN94321.1 - 0.0044 16.4 3.0 0.0044 16.4 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-Sec23_Sec24 PF04810.10 EDN94321.1 - 0.034 13.7 0.1 6.3 6.4 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger NmrA PF05368.8 EDN94322.1 - 1.4e-31 109.5 0.0 1.8e-29 102.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN94322.1 - 0.00011 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN94322.1 - 0.0011 17.7 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EDN94322.1 - 0.0021 17.7 0.2 0.0052 16.4 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EDN94322.1 - 0.0088 15.4 0.1 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDN94322.1 - 0.02 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase UBN_AB PF14075.1 EDN94323.1 - 0.063 12.9 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain HflK_N PF12221.3 EDN94323.1 - 0.25 11.1 0.7 25 4.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane protein N terminal DUF4448 PF14610.1 EDN94325.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AAA PF00004.24 EDN94326.1 - 5e-91 301.7 0.0 4.1e-46 156.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDN94326.1 - 1.3e-14 53.8 0.0 2.3e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN94326.1 - 1.8e-12 47.6 0.1 4.7e-05 23.4 0.0 3.3 3 1 1 4 4 2 2 AAA ATPase domain AAA_22 PF13401.1 EDN94326.1 - 4.6e-11 42.9 0.1 0.0026 17.9 0.0 4.7 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EDN94326.1 - 3.1e-10 39.9 1.1 0.00087 19.0 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN94326.1 - 8.1e-10 38.8 0.0 0.0013 18.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EDN94326.1 - 1.2e-09 38.1 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN94326.1 - 1.4e-09 37.3 0.0 0.00064 18.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EDN94326.1 - 1.5e-09 38.6 0.0 0.00073 20.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EDN94326.1 - 3.5e-09 36.6 0.0 0.0028 17.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EDN94326.1 - 8.2e-09 35.0 0.2 0.0051 16.5 0.0 3.6 3 1 0 3 3 3 2 Part of AAA domain TIP49 PF06068.8 EDN94326.1 - 5.1e-08 32.0 0.1 0.0023 16.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EDN94326.1 - 7.1e-08 32.0 5.5 0.58 9.5 0.0 5.0 2 2 1 5 5 5 3 AAA domain IstB_IS21 PF01695.12 EDN94326.1 - 7.5e-08 31.9 0.0 0.0094 15.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EDN94326.1 - 1.8e-07 31.3 0.0 0.013 15.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EDN94326.1 - 3.2e-07 29.7 0.7 0.026 13.6 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDN94326.1 - 1e-06 28.4 0.1 0.11 12.1 0.0 3.7 2 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.1 EDN94326.1 - 1.2e-06 28.6 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EDN94326.1 - 2e-06 27.4 0.0 0.024 14.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EDN94326.1 - 3.9e-06 26.1 0.2 0.029 13.4 0.0 3.2 3 0 0 3 3 3 2 KaiC AAA_18 PF13238.1 EDN94326.1 - 5e-06 26.8 0.0 0.084 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EDN94326.1 - 2.2e-05 24.7 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Cytidylate_kin2 PF13189.1 EDN94326.1 - 3e-05 24.0 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 EDN94326.1 - 3.5e-05 23.8 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EDN94326.1 - 4.8e-05 23.1 0.0 0.7 9.5 0.0 3.2 3 1 0 3 3 2 2 Archaeal ATPase Sigma54_activat PF00158.21 EDN94326.1 - 5.4e-05 22.7 0.0 0.17 11.3 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EDN94326.1 - 0.00012 21.6 0.1 0.29 10.6 0.0 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EDN94326.1 - 0.00015 20.5 0.0 0.18 10.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein SKI PF01202.17 EDN94326.1 - 0.00039 20.3 0.1 0.99 9.2 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase Viral_helicase1 PF01443.13 EDN94326.1 - 0.00042 19.9 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EDN94326.1 - 0.00045 19.1 0.7 0.27 10.0 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain PhoH PF02562.11 EDN94326.1 - 0.00059 19.1 0.2 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 EDN94326.1 - 0.00085 18.3 0.0 0.029 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 EDN94326.1 - 0.0014 18.4 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EDN94326.1 - 0.002 17.7 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EDN94326.1 - 0.0022 16.8 0.0 0.52 9.0 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase Parvo_NS1 PF01057.12 EDN94326.1 - 0.0022 16.8 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EDN94326.1 - 0.0023 17.5 0.2 1.7 8.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EDN94326.1 - 0.012 15.2 0.2 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDN94326.1 - 0.017 14.8 0.8 1.9 8.1 0.0 3.2 3 0 0 3 3 3 0 NTPase T2SE PF00437.15 EDN94326.1 - 0.025 13.4 0.0 3.7 6.3 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF2075 PF09848.4 EDN94326.1 - 0.04 12.8 0.0 4.4 6.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EDN94326.1 - 0.055 13.0 0.0 3.6 7.1 0.0 2.9 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EDN94326.1 - 0.15 12.3 1.3 4.3 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Snf7 PF03357.16 EDN94327.1 - 3.6e-14 52.5 23.2 2e-11 43.5 5.8 2.4 2 1 1 3 3 3 2 Snf7 Prefoldin_2 PF01920.15 EDN94327.1 - 0.44 10.3 8.9 0.39 10.5 2.7 2.4 1 1 1 2 2 2 0 Prefoldin subunit DUF2293 PF10056.4 EDN94328.1 - 9.6e-30 102.4 0.1 9.6e-30 102.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Nucleoplasmin PF03066.10 EDN94328.1 - 0.45 10.0 10.3 1.1 8.7 7.1 1.6 1 0 0 1 1 1 0 Nucleoplasmin 3Beta_HSD PF01073.14 EDN94329.1 - 0.00017 20.3 0.0 0.029 13.0 0.0 2.0 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN94329.1 - 0.035 13.5 0.0 1.5 8.2 0.0 2.1 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family FerA PF08165.6 EDN94330.1 - 0.093 12.4 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 FerA (NUC095) domain Mito_carr PF00153.22 EDN94331.1 - 2.2e-47 158.6 8.7 1.4e-18 66.3 0.3 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4633 PF15464.1 EDN94331.1 - 0.053 13.3 0.1 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Complex1_LYR PF05347.10 EDN94332.1 - 4.8e-08 32.6 0.4 7.4e-08 32.0 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN94332.1 - 0.00039 20.5 0.3 0.00049 20.2 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EDN94333.1 - 2e-25 88.3 0.4 2e-25 88.3 0.3 2.9 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EDN94333.1 - 1.9e-14 53.5 20.3 1.9e-14 53.5 14.1 4.1 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EDN94333.1 - 7e-08 32.1 9.8 7e-08 32.1 6.8 4.1 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN94333.1 - 8.7e-06 25.6 8.5 8.7e-06 25.6 5.9 4.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN94333.1 - 0.00045 19.8 8.6 0.00045 19.8 6.0 5.4 3 2 1 4 4 4 1 zinc-RING finger domain Nop14 PF04147.7 EDN94333.1 - 3.9 5.2 10.8 0.92 7.3 5.5 1.4 2 0 0 2 2 2 0 Nop14-like family MOZART1 PF12554.3 EDN94334.1 - 7.8e-25 86.0 0.3 9.8e-25 85.7 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PilJ PF13675.1 EDN94334.1 - 0.022 15.0 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Metal_resist PF13801.1 EDN94334.1 - 0.16 11.9 0.9 0.71 9.8 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Spindle_Spc25 PF08234.7 EDN94335.1 - 2.9e-24 84.8 0.9 4.7e-24 84.1 0.1 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 EDN94335.1 - 0.0015 18.0 10.3 0.0028 17.1 7.1 1.4 1 0 0 1 1 1 1 Intermediate filament protein Striatin PF08232.7 EDN94335.1 - 0.29 11.4 7.5 0.032 14.5 1.6 2.0 1 1 1 2 2 2 0 Striatin family DUF4614 PF15391.1 EDN94335.1 - 0.43 10.3 7.3 2.3 7.9 5.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) Atg14 PF10186.4 EDN94335.1 - 4.8 6.0 10.7 3.8 6.3 6.4 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Rrn6 PF10214.4 EDN94336.1 - 5.6e-71 239.6 0.0 1.1e-27 96.6 0.0 3.0 1 1 2 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Gemini_coat PF00844.13 EDN94336.1 - 0.018 14.2 0.6 0.031 13.5 0.4 1.3 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family PITH PF06201.8 EDN94337.1 - 3.5e-50 169.7 0.2 4.3e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 PITH domain PAZ_siRNAbind PF12212.3 EDN94338.1 - 0.1 12.2 0.2 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain RsgI_N PF12791.2 EDN94338.1 - 0.12 12.0 0.7 0.53 9.9 0.3 2.2 1 1 0 1 1 1 0 Anti-sigma factor N-terminus PBP_sp32 PF07222.7 EDN94338.1 - 2.7 7.1 5.6 3.6 6.6 3.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_L3 PF00297.17 EDN94339.1 - 9e-37 126.8 5.6 1.4e-35 122.9 3.9 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 DUF1466 PF07326.6 EDN94339.1 - 0.0072 15.6 0.4 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1466) Coa1 PF08695.5 EDN94340.1 - 6.2e-20 70.8 0.1 7e-20 70.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4231 PF14015.1 EDN94341.1 - 0.013 15.4 1.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3278 PF11683.3 EDN94341.1 - 0.087 12.8 0.2 0.81 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Ank_2 PF12796.2 EDN94342.1 - 3.5e-44 149.0 11.8 5.1e-15 55.5 0.8 5.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SPX PF03105.14 EDN94342.1 - 2.8e-28 99.4 13.9 6e-16 59.0 4.6 2.3 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EDN94342.1 - 4.9e-28 95.5 12.3 0.00088 18.9 0.4 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EDN94342.1 - 7.9e-27 93.1 5.2 6.9e-06 26.4 0.0 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN94342.1 - 2.9e-19 67.2 13.0 0.0013 18.8 0.1 9.2 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 EDN94342.1 - 3.1e-17 62.1 9.5 0.00021 21.4 0.0 7.9 3 2 6 9 9 9 6 Ankyrin repeats (many copies) GDPD PF03009.12 EDN94342.1 - 9.2e-10 38.4 0.0 1.2e-08 34.7 0.0 2.6 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF3447 PF11929.3 EDN94342.1 - 0.049 13.4 0.2 1.7 8.4 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) Rsa3 PF14615.1 EDN94342.1 - 0.1 11.9 1.1 0.95 8.8 0.1 2.7 2 0 0 2 2 2 0 Ribosome-assembly protein 3 Orn_Arg_deC_N PF02784.11 EDN94342.1 - 0.19 10.8 0.2 0.33 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain CUE PF02845.11 EDN94343.1 - 1.4e-12 46.8 0.0 2.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain INO80_Ies4 PF08193.6 EDN94345.1 - 3.2e-76 256.2 23.7 3.2e-76 256.2 16.4 1.6 2 0 0 2 2 2 1 INO80 complex subunit Ies4 OSCP PF00213.13 EDN94346.1 - 0.061 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CLTH PF10607.4 EDN94347.1 - 5.8e-34 116.8 0.3 9.7e-34 116.1 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EDN94347.1 - 5.8e-20 71.6 0.2 1e-19 70.8 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EDN94347.1 - 3.7e-05 23.3 0.2 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 LisH Phosphoprotein PF00922.12 EDN94349.1 - 0.0021 17.3 8.2 0.0023 17.2 5.7 1.0 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein SR-25 PF10500.4 EDN94349.1 - 0.12 11.7 10.7 0.13 11.6 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 EDN94349.1 - 0.37 10.1 11.7 0.4 10.0 8.1 1.0 1 0 0 1 1 1 0 Vta1 like DUF4614 PF15391.1 EDN94349.1 - 0.51 10.0 7.8 0.56 9.9 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 EDN94349.1 - 0.66 8.7 2.8 0.69 8.7 1.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Apc15p PF05841.6 EDN94349.1 - 1.3 9.7 5.2 1.7 9.3 3.6 1.2 1 0 0 1 1 1 0 Apc15p protein MSP1_C PF07462.6 EDN94349.1 - 2.6 6.3 3.9 2.7 6.2 2.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CAF-1_p150 PF11600.3 EDN94349.1 - 4.8 6.5 8.6 5.3 6.3 6.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2731 PF10806.3 EDN94351.1 - 5e-05 23.5 0.1 0.00039 20.6 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EDN94351.1 - 0.00074 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EDN94351.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN94351.1 - 0.031 14.1 1.0 0.072 12.9 0.6 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Exo_endo_phos_2 PF14529.1 EDN94353.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Kri1_C PF12936.2 EDN94355.1 - 0.062 13.2 0.0 0.069 13.0 0.0 1.0 1 0 0 1 1 1 0 KRI1-like family C-terminal Dsh_C PF12316.3 EDN94356.1 - 3 7.8 24.2 2.2 8.3 4.5 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal VWA_3 PF13768.1 EDN94358.1 - 1.4e-40 138.4 0.0 2.3e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ATP_synt_I PF03899.10 EDN94360.1 - 0.04 14.0 0.1 0.053 13.6 0.1 1.1 1 0 0 1 1 1 0 ATP synthase I chain RGS PF00615.14 EDN94361.1 - 3.6e-08 33.5 0.0 1.9e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain ATP1G1_PLM_MAT8 PF02038.11 EDN94361.1 - 1 8.4 3.5 3.9 6.5 0.9 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family ACOX PF01756.14 EDN94365.1 - 2.4e-35 121.6 0.1 4.7e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EDN94365.1 - 1.8e-27 96.1 0.2 4.2e-27 94.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EDN94365.1 - 3.1e-12 45.7 0.5 9.6e-12 44.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EDN94365.1 - 5.8e-08 32.9 0.2 0.00036 20.6 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L7Ae PF01248.21 EDN94366.1 - 1.7e-25 88.3 0.0 2e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDN94366.1 - 0.00058 19.7 0.0 0.00077 19.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EDN94366.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain ATP-synt_C PF00137.16 EDN94367.1 - 3.4e-32 110.1 31.1 1e-18 66.9 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EDN94367.1 - 0.16 11.0 0.9 3.8 6.5 0.1 2.1 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 EDN94367.1 - 0.26 10.8 4.6 0.072 12.6 0.8 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A CMD PF02627.15 EDN94369.1 - 3.7e-08 33.0 0.0 1.8e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.16 EDN94371.1 - 4e-10 39.4 6.9 4e-10 39.4 4.8 1.6 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN94371.1 - 4.1e-05 23.3 8.6 4.1e-05 23.3 6.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper PilJ PF13675.1 EDN94371.1 - 0.0019 18.4 2.3 0.0026 18.0 1.6 1.2 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_Maf PF03131.12 EDN94371.1 - 0.0074 16.5 9.4 0.0074 16.5 6.5 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor V_ATPase_I PF01496.14 EDN94371.1 - 0.018 12.9 1.4 0.018 12.9 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EDN94371.1 - 0.023 14.3 3.1 0.028 14.0 2.2 1.2 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EDN94371.1 - 0.025 14.3 1.0 0.044 13.5 0.7 1.3 1 0 0 1 1 1 0 Prefoldin subunit HALZ PF02183.13 EDN94371.1 - 0.03 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spc7 PF08317.6 EDN94371.1 - 0.059 12.0 0.8 0.075 11.6 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMCO5 PF14992.1 EDN94371.1 - 0.065 12.3 1.3 0.065 12.3 0.9 1.1 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.1 EDN94371.1 - 0.09 11.9 5.9 0.12 11.5 4.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EDN94371.1 - 0.96 8.4 3.9 1.1 8.2 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Transketolase_N PF00456.16 EDN94373.1 - 1.4e-149 497.4 0.1 2.1e-149 496.8 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EDN94373.1 - 3.8e-46 156.8 0.0 6.2e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN94373.1 - 6.8e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EDN94373.1 - 5e-07 28.9 0.1 4.1e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EDN94373.1 - 0.016 13.9 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Scm3 PF10384.4 EDN94373.1 - 0.04 13.4 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 TPP_enzyme_N PF02776.13 EDN94373.1 - 0.14 11.6 0.3 0.96 8.9 0.0 2.4 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF4589 PF15252.1 EDN94374.1 - 0.25 11.1 3.9 0.077 12.8 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) TMEM192 PF14802.1 EDN94375.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.2 3 0 0 3 3 3 0 TMEM192 family FlaC_arch PF05377.6 EDN94375.1 - 0.34 10.8 38.0 0.35 10.7 0.4 6.6 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EDN94375.1 - 1 8.4 3.8 1.8 7.6 2.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APH PF01636.18 EDN94377.1 - 0.041 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 EDN94378.1 - 1.6e-11 43.5 0.0 2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EDN94379.1 - 1.5e-24 86.3 0.7 5.6e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 Clathrin adaptor complex small chain CagE_TrbE_VirB PF03135.9 EDN94379.1 - 0.0067 16.2 0.2 0.0077 16.0 0.1 1.1 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system DUF629 PF04780.7 EDN94379.1 - 0.017 13.7 0.1 0.02 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Maf1 PF09174.5 EDN94380.1 - 1.1e-57 194.7 0.0 1.6e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator MFS_2 PF13347.1 EDN94381.1 - 0.0016 16.8 5.8 0.0016 16.8 4.0 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein hSac2 PF12456.3 EDN94383.1 - 1e-36 124.7 0.0 1.6e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Inositol phosphatase DUF3185 PF11381.3 EDN94383.1 - 0.096 12.4 0.1 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Syja_N PF02383.13 EDN94384.1 - 1.1e-55 188.7 0.0 1.5e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF3115 PF11312.3 EDN94385.1 - 3.6e-40 137.7 0.0 4.3e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUF1864 PF08933.6 EDN94386.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) HATPase_c PF02518.21 EDN94387.1 - 4.6e-29 100.3 0.0 1.3e-28 98.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN94387.1 - 5.6e-25 87.5 0.3 1.2e-24 86.4 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EDN94387.1 - 5.1e-13 48.8 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EDN94387.1 - 0.00018 21.6 1.7 0.4 10.9 0.0 3.1 3 0 0 3 3 3 2 HAMP domain Phage_holin PF04688.8 EDN94387.1 - 0.063 12.8 0.4 0.14 11.7 0.3 1.5 1 0 0 1 1 1 0 Phage lysis protein, holin CobT PF06213.7 EDN94388.1 - 0.35 9.9 17.1 0.021 13.9 7.3 2.2 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EDN94388.1 - 0.95 9.0 16.3 0.24 11.0 8.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 EDN94388.1 - 1.2 8.9 12.6 4.7 7.0 8.7 2.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 EDN94388.1 - 1.8 6.5 13.9 3.3 5.6 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EDN94388.1 - 4.1 5.1 9.3 6.2 4.5 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.24 EDN94389.1 - 2.3e-15 56.9 0.0 5.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN94389.1 - 0.0008 19.4 0.1 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN94389.1 - 0.014 16.2 0.1 0.062 14.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN94389.1 - 0.028 14.1 0.1 0.082 12.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EDN94389.1 - 0.051 13.7 0.1 0.19 11.8 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 EDN94389.1 - 1.7 8.1 13.8 16 4.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Aldolase_II PF00596.16 EDN94390.1 - 1.9e-46 158.0 0.2 2.6e-46 157.5 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DDE_1 PF03184.14 EDN94391.1 - 9.1e-12 44.5 0.0 2e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN94391.1 - 2.3e-06 27.3 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN94392.1 - 0.0057 16.5 6.8 0.0096 15.8 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle ORMDL PF04061.9 EDN94395.1 - 1.6e-59 199.3 2.8 1.8e-59 199.1 1.9 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EDN94395.1 - 0.14 11.8 3.8 0.14 11.7 1.0 1.8 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-RanBP PF00641.13 EDN94396.1 - 2.3 7.4 6.5 0.52 9.4 0.1 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-CCHC PF00098.18 EDN94396.1 - 8.2 6.5 22.7 0.15 12.0 3.0 4.2 4 0 0 4 4 4 0 Zinc knuckle RVT_1 PF00078.22 EDN94397.1 - 1.1e-36 126.1 0.0 1.8e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN94397.1 - 4.9e-10 39.8 0.0 9.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN94398.1 - 3.6e-13 49.1 0.1 6.3e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN94398.1 - 0.00095 19.1 0.1 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_T PF00929.19 EDN94400.1 - 4.9e-07 30.1 0.0 7.5e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Exonuclease DUF676 PF05057.9 EDN94401.1 - 1.7e-50 171.3 0.0 2.4e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EDN94401.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDN94401.1 - 0.00034 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EDN94401.1 - 0.00048 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDN94401.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Rep_fac_C PF08542.6 EDN94402.1 - 4.6e-23 81.0 0.1 1.1e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDN94402.1 - 1.1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDN94402.1 - 4.2e-06 26.9 0.1 1e-05 25.7 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN94402.1 - 0.00017 21.7 1.2 0.0022 18.1 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN94402.1 - 0.0038 17.2 0.7 0.03 14.3 0.3 2.4 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EDN94402.1 - 0.0051 16.8 0.2 0.31 11.0 0.0 2.4 1 1 0 2 2 2 1 Sigma-54 interaction domain DUF2861 PF11060.3 EDN94402.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) SNF2_N PF00176.18 EDN94402.1 - 0.034 12.9 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 EDN94402.1 - 0.078 11.5 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_5 PF07728.9 EDN94402.1 - 0.088 12.5 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-C2H2_4 PF13894.1 EDN94403.1 - 0.00012 22.1 13.7 0.34 11.3 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN94403.1 - 0.0014 18.8 14.7 0.11 12.8 1.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Bap31 PF05529.7 EDN94403.1 - 0.058 12.8 4.5 0.096 12.1 3.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EDN94403.1 - 0.24 11.2 8.1 0.48 10.2 5.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF607 PF04678.8 EDN94403.1 - 0.71 9.7 2.6 1.2 9.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 APG6 PF04111.7 EDN94403.1 - 1.5 7.8 7.1 2.2 7.2 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MFS_1 PF07690.11 EDN94406.1 - 5.1e-38 130.6 43.2 5.1e-38 130.6 30.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 EDN94408.1 - 3.1e-30 104.9 0.0 5.4e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.17 EDN94408.1 - 0.068 12.8 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 PA domain Spermine_synth PF01564.12 EDN94409.1 - 2.7e-99 331.0 0.0 3.5e-99 330.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EDN94409.1 - 0.00065 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EDN94409.1 - 0.0023 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_31 PF13847.1 EDN94409.1 - 0.0038 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN94409.1 - 0.028 14.8 0.2 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EDN94409.1 - 0.1 11.7 0.1 0.58 9.3 0.0 1.8 1 1 1 2 2 2 0 O-methyltransferase DREV PF05219.7 EDN94409.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.1 EDN94409.1 - 0.11 12.1 0.0 0.43 10.3 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain G-alpha PF00503.15 EDN94413.1 - 1.5e-116 389.3 1.5 1.8e-116 389.0 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EDN94413.1 - 6.2e-15 54.8 0.9 2.5e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN94413.1 - 0.0058 15.7 4.7 0.15 11.1 0.1 2.6 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN94413.1 - 0.016 15.6 0.0 3.1 8.3 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EDN94413.1 - 0.02 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN94413.1 - 0.1 12.0 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EDN94413.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain MIS13 PF08202.6 EDN94414.1 - 8.7e-51 172.7 0.2 1.5e-50 172.0 0.1 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family NmrA PF05368.8 EDN94415.1 - 1e-06 28.2 0.0 1.1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN94415.1 - 0.005 16.8 0.0 0.08 12.9 0.0 2.5 1 1 1 2 2 2 1 NADH(P)-binding Adeno_E3_CR2 PF02439.10 EDN94417.1 - 8.9e-05 21.9 0.9 0.00016 21.1 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1191 PF06697.7 EDN94417.1 - 0.00063 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EDN94417.1 - 0.018 13.3 0.2 0.032 12.4 0.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EDN94417.1 - 0.11 12.9 0.1 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.6 EDN94417.1 - 0.15 11.8 0.5 0.39 10.5 0.4 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Syndecan PF01034.15 EDN94417.1 - 0.15 11.7 0.5 0.27 10.8 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Neurensin PF14927.1 EDN94417.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Neurensin DEAD PF00270.24 EDN94418.1 - 3.3e-31 108.0 0.2 5.1e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94418.1 - 3.8e-25 87.5 0.1 1.1e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDN94418.1 - 0.026 14.2 2.1 0.21 11.3 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain Helicase_C_2 PF13307.1 EDN94418.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain FCH PF00611.18 EDN94419.1 - 4.4e-22 78.0 0.0 4.4e-22 78.0 0.0 3.1 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EDN94419.1 - 2.4e-19 68.6 0.4 4.3e-12 45.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EDN94419.1 - 2.3e-15 55.7 0.2 3.3e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EDN94419.1 - 1.3e-14 53.6 5.6 2.2e-14 52.9 3.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 EDN94419.1 - 8.1e-05 22.7 0.8 0.0018 18.4 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.12 EDN94419.1 - 0.0016 17.9 0.1 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Allexi_40kDa PF05549.6 EDN94419.1 - 0.048 12.9 6.1 0.017 14.4 0.9 2.3 2 1 0 2 2 2 0 Allexivirus 40kDa protein C1_2 PF03107.11 EDN94419.1 - 0.56 10.3 7.8 0.99 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain YlqD PF11068.3 EDN94419.1 - 2.7 8.0 16.9 1.5 8.8 1.9 2.9 3 0 0 3 3 3 0 YlqD protein Ax_dynein_light PF10211.4 EDN94419.1 - 4.2 7.1 19.5 0.059 13.2 4.0 2.9 3 0 0 3 3 3 0 Axonemal dynein light chain COG2 PF06148.6 EDN94419.1 - 4.9 7.0 8.4 2.2 8.1 1.9 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ax_dynein_light PF10211.4 EDN94420.1 - 0.0075 16.1 1.8 0.0089 15.8 1.3 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Striatin PF08232.7 EDN94420.1 - 0.0077 16.5 3.4 0.0097 16.2 2.3 1.1 1 0 0 1 1 1 1 Striatin family ALIX_LYPXL_bnd PF13949.1 EDN94420.1 - 0.0089 15.0 1.9 0.01 14.7 1.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV vWA-TerF-like PF10138.4 EDN94420.1 - 0.009 15.8 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF848 PF05852.6 EDN94420.1 - 0.016 15.0 0.8 0.017 14.9 0.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Allexi_40kDa PF05549.6 EDN94420.1 - 0.018 14.3 0.5 0.019 14.2 0.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Phage_GP20 PF06810.6 EDN94420.1 - 0.02 14.3 3.3 0.023 14.1 2.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3829 PF12889.2 EDN94420.1 - 0.02 14.0 0.4 0.022 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) GP41 PF00517.12 EDN94420.1 - 0.029 13.9 0.3 0.041 13.4 0.2 1.2 1 0 0 1 1 1 0 Retroviral envelope protein SNARE PF05739.14 EDN94420.1 - 0.057 13.1 3.1 0.11 12.1 2.1 1.4 1 0 0 1 1 1 0 SNARE domain DUF2664 PF10867.3 EDN94420.1 - 0.061 13.9 1.8 0.089 13.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Herpes_UL25 PF01499.11 EDN94420.1 - 0.061 11.6 2.8 0.072 11.3 2.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family HSBP1 PF06825.7 EDN94420.1 - 0.063 12.8 4.6 0.49 10.0 3.3 2.5 1 1 1 2 2 2 0 Heat shock factor binding protein 1 TMF_DNA_bd PF12329.3 EDN94420.1 - 0.078 12.8 8.7 2.3 8.0 6.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EDN94420.1 - 0.081 13.2 1.7 0.096 13.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EDN94420.1 - 0.089 12.9 4.1 1.1 9.3 2.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4132 PF13569.1 EDN94420.1 - 0.089 12.3 1.8 0.15 11.6 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) Tropomyosin_1 PF12718.2 EDN94420.1 - 0.095 12.5 5.6 0.13 12.0 3.9 1.2 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.10 EDN94420.1 - 0.097 12.1 5.6 4.9 6.7 3.9 2.1 1 1 0 1 1 1 0 Septum formation initiator LUC7 PF03194.10 EDN94420.1 - 0.11 12.0 2.1 0.12 11.9 1.5 1.1 1 0 0 1 1 1 0 LUC7 N_terminus TBCA PF02970.11 EDN94420.1 - 0.11 12.6 4.5 0.58 10.2 3.1 2.0 1 1 0 1 1 1 0 Tubulin binding cofactor A SlyX PF04102.7 EDN94420.1 - 0.11 12.8 5.8 0.71 10.2 4.0 2.2 1 1 0 1 1 1 0 SlyX CENP-F_leu_zip PF10473.4 EDN94420.1 - 0.12 12.2 6.1 0.54 10.1 4.2 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSP70 PF00012.15 EDN94420.1 - 0.13 10.1 2.8 0.14 9.9 1.9 1.0 1 0 0 1 1 1 0 Hsp70 protein AAA_23 PF13476.1 EDN94420.1 - 0.14 12.4 3.0 0.17 12.2 2.1 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.8 EDN94420.1 - 0.15 11.8 5.3 0.26 11.0 3.6 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Takusan PF04822.8 EDN94420.1 - 0.15 11.8 3.9 0.28 10.9 2.7 1.4 1 1 0 1 1 1 0 Takusan MRF_C1 PF13887.1 EDN94420.1 - 0.15 11.0 4.6 2.9 6.9 0.4 2.4 2 1 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF4404 PF14357.1 EDN94420.1 - 0.24 11.8 2.3 0.32 11.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) OmpH PF03938.9 EDN94420.1 - 0.35 10.8 5.1 0.41 10.5 3.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.6 EDN94420.1 - 0.37 11.2 3.2 0.63 10.4 2.0 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal AKNA PF12443.3 EDN94420.1 - 0.44 10.5 3.7 0.37 10.8 1.4 1.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor FlaC_arch PF05377.6 EDN94420.1 - 1.4 8.8 6.6 2.3 8.1 2.5 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EDN94420.1 - 1.8 8.4 4.8 4.2 7.2 3.3 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.16 EDN94420.1 - 1.8 8.5 5.7 2.8 7.9 1.6 2.1 1 1 1 2 2 2 0 bZIP transcription factor PspB PF06667.7 EDN94420.1 - 1.9 8.5 3.8 18 5.3 1.4 2.4 1 1 1 2 2 2 0 Phage shock protein B IncA PF04156.9 EDN94420.1 - 2.1 7.8 5.5 3.5 7.1 3.5 1.4 1 1 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EDN94420.1 - 7.2 6.5 8.7 9.3 6.1 2.2 2.6 1 1 1 2 2 2 0 Basic region leucine zipper GST_N PF02798.15 EDN94422.1 - 2.9e-17 62.5 0.0 4.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN94422.1 - 7.8e-17 61.2 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN94422.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDN94422.1 - 3.6e-12 46.0 0.0 8.9e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN94422.1 - 8.4e-09 35.2 0.1 1.5e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN94422.1 - 2.3e-06 28.0 0.1 3.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1751 PF08551.5 EDN94428.1 - 7.9e-25 87.0 4.1 7.9e-25 87.0 2.9 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) WD40 PF00400.27 EDN94429.1 - 1.2e-09 37.6 2.7 0.053 13.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN94429.1 - 0.00088 19.0 0.1 1.2 8.7 0.0 2.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Big_2 PF02368.13 EDN94429.1 - 0.0064 16.3 3.9 2.5 8.0 0.0 3.5 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 2) TPR_1 PF00515.23 EDN94431.1 - 2.7e-49 162.8 28.3 5.1e-08 32.1 0.0 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EDN94431.1 - 5.3e-48 160.5 39.5 1.4e-13 50.2 1.3 6.2 2 1 7 9 9 9 9 TPR repeat TPR_2 PF07719.12 EDN94431.1 - 2.5e-43 142.5 22.2 1.9e-05 24.2 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EDN94431.1 - 1.6e-34 115.0 19.2 9.4e-06 25.0 0.5 10.2 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EDN94431.1 - 1.5e-31 108.3 11.4 1.9e-07 31.5 0.1 6.8 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EDN94431.1 - 1.1e-29 102.1 18.6 3e-06 27.0 1.4 6.8 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EDN94431.1 - 4.8e-25 85.6 11.7 0.0015 18.5 0.1 10.1 10 1 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EDN94431.1 - 4.2e-23 79.2 12.3 0.0018 17.8 0.0 9.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDN94431.1 - 2.8e-21 74.0 21.7 0.0019 18.6 0.0 9.8 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_6 PF13174.1 EDN94431.1 - 5.7e-21 73.4 20.1 0.0082 16.5 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDN94431.1 - 3.1e-20 72.2 19.0 0.0013 19.0 0.1 6.0 4 1 1 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EDN94431.1 - 8.4e-13 48.2 9.9 1.3e-07 31.6 0.8 4.2 3 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN94431.1 - 1e-10 41.2 11.9 0.00095 18.9 0.1 7.1 1 1 4 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.4 EDN94431.1 - 1.3e-07 31.6 10.9 0.026 14.4 0.1 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EDN94431.1 - 7.8e-05 21.8 20.4 0.034 13.2 3.9 5.5 2 1 2 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 EDN94431.1 - 0.0058 16.1 2.4 0.5 9.7 0.0 3.2 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 EDN94431.1 - 0.013 15.4 14.5 9.3 6.3 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 EDN94431.1 - 0.04 14.0 11.5 0.89 9.7 0.0 4.7 5 1 1 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.1 EDN94431.1 - 0.71 8.9 15.7 6.1 5.8 1.4 4.5 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.13 EDN94431.1 - 9.6 6.1 17.5 8.3 6.3 0.3 5.6 6 2 0 6 6 6 0 MIT (microtubule interacting and transport) domain AhpC-TSA_2 PF13911.1 EDN94432.1 - 1.1e-18 67.1 0.0 2.7e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EDN94432.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Dehydratase_MU PF02288.10 EDN94433.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit IDO PF01231.13 EDN94434.1 - 1.2e-173 577.4 0.0 1.4e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EDN94435.1 - 1.8e-37 127.6 0.1 3.5e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EDN94435.1 - 8.7e-21 73.3 0.0 1.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain STE2 PF02116.10 EDN94437.1 - 1.3e-95 319.7 14.8 1.6e-95 319.4 10.2 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF3129 PF11327.3 EDN94438.1 - 3.2e-69 232.4 14.1 4.3e-69 232.0 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Methyltransf_FA PF12248.3 EDN94438.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase LRR_4 PF12799.2 EDN94441.1 - 0.0051 16.4 17.5 0.17 11.5 0.5 6.0 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EDN94441.1 - 0.03 14.3 14.9 30 5.0 0.0 7.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 EDN94441.1 - 9.5 6.9 9.7 51 4.7 0.0 6.2 7 0 0 7 7 7 0 Leucine rich repeat Ribosomal_L18p PF00861.17 EDN94442.1 - 4e-43 146.3 0.1 7.8e-43 145.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EDN94442.1 - 9.7e-33 112.6 8.2 9.7e-33 112.6 5.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3640 PF12342.3 EDN94443.1 - 0.0051 16.3 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3640) ADIP PF11559.3 EDN94444.1 - 8.2e-28 97.2 10.0 8.2e-28 97.2 7.0 3.0 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding HAD_2 PF13419.1 EDN94445.1 - 1.9e-12 47.7 0.0 3.4e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN94445.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TPR_11 PF13414.1 EDN94446.1 - 1.6e-10 40.4 0.4 2.3e-07 30.3 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN94446.1 - 4e-08 32.5 2.9 0.13 12.2 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN94446.1 - 2.7e-07 29.9 8.6 0.014 14.9 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN94446.1 - 1.2e-05 25.1 3.2 0.00063 19.6 1.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat LRR_8 PF13855.1 EDN94446.1 - 0.00011 21.9 15.3 0.14 11.9 0.0 5.5 5 2 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EDN94446.1 - 0.00036 20.2 2.4 0.014 15.3 0.0 4.8 6 0 0 6 6 5 1 Leucine Rich repeat F-box-like PF12937.2 EDN94446.1 - 0.00088 18.9 0.3 0.0031 17.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDN94446.1 - 0.0022 17.6 0.7 0.0044 16.6 0.1 1.9 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 EDN94446.1 - 0.0067 16.2 4.9 59 4.2 0.0 6.5 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EDN94446.1 - 0.0081 16.1 11.8 8.2 7.1 0.0 7.3 8 0 0 8 8 7 1 Leucine rich repeat TPR_8 PF13181.1 EDN94446.1 - 0.014 15.1 1.4 12 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 EDN94446.1 - 0.021 14.4 0.0 0.021 14.4 0.0 5.9 5 2 2 7 7 6 0 Leucine Rich repeats (2 copies) TPR_16 PF13432.1 EDN94446.1 - 0.041 14.5 0.6 0.42 11.3 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1699 PF08004.6 EDN94446.1 - 0.056 12.9 0.2 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) HET PF06985.6 EDN94447.1 - 8.1e-26 90.8 0.2 1.5e-25 90.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF605 PF04652.11 EDN94450.1 - 8.4 5.6 9.9 9.7 5.4 6.8 1.0 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 EDN94451.1 - 1.3e-28 99.5 1.0 2e-28 98.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN94451.1 - 1.3e-06 28.2 13.0 2.1e-06 27.5 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EDN94452.1 - 1.8e-22 79.3 0.0 2.5e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EDN94452.1 - 6.9e-13 48.9 0.0 2.2e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EDN94452.1 - 1.6e-07 31.3 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.1 EDN94453.1 - 5.2e-17 62.4 0.0 1.8e-11 44.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN94453.1 - 6.6e-17 61.9 2.1 5.5e-09 36.1 0.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EDN94453.1 - 0.0002 21.1 0.7 0.37 10.4 0.1 2.2 1 1 1 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 EDN94453.1 - 0.14 11.2 0.1 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polyketide_cyc2 PF10604.4 EDN94455.1 - 3.4e-08 33.7 0.0 4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ran_BP1 PF00638.13 EDN94457.1 - 2.9e-14 53.1 0.2 2e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain Nucleoporin_FG PF13634.1 EDN94457.1 - 6.5e-05 23.1 76.9 0.00023 21.3 23.8 12.3 5 4 7 12 12 12 6 Nucleoporin FG repeat region Nucleoplasmin PF03066.10 EDN94457.1 - 0.13 11.8 5.8 0.35 10.3 0.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin MMR_HSR1_C PF08438.5 EDN94460.1 - 1.7e-32 111.8 0.0 3.1e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EDN94460.1 - 8.8e-06 25.6 0.0 2.2e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase VirB8 PF04335.8 EDN94460.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein Hairy_orange PF07527.8 EDN94461.1 - 0.057 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Hairy Orange Pmp3 PF01679.12 EDN94462.1 - 5.6e-27 93.1 6.2 6.2e-27 93.0 4.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EDN94462.1 - 3.2 7.4 8.8 0.26 10.9 2.3 1.8 2 0 0 2 2 2 0 Conserved TM helix Ribosomal_L22e PF01776.12 EDN94463.1 - 6.8e-45 151.6 0.9 7.4e-45 151.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Yae1_N PF09811.4 EDN94464.1 - 2.8e-05 23.5 16.5 0.29 10.7 11.4 2.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SCP2 PF02036.12 EDN94465.1 - 4.1e-24 84.8 0.1 4.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EDN94465.1 - 4.1e-05 23.5 0.0 5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Fungal_trans PF04082.13 EDN94466.1 - 6.4e-30 103.8 1.8 1.6e-29 102.5 1.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN94466.1 - 4.5e-08 32.8 14.2 7.8e-08 32.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.2 EDN94466.1 - 0.27 10.9 3.5 0.25 10.9 0.7 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) SET PF00856.23 EDN94468.1 - 2.4e-05 24.6 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 SET domain P-mevalo_kinase PF04275.9 EDN94468.1 - 0.0086 15.7 0.1 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase PIG-F PF06699.6 EDN94469.1 - 1.6e-55 187.9 4.5 2.1e-55 187.6 3.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.11 EDN94470.1 - 1.8e-57 194.2 0.1 2.1e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EDN94470.1 - 0.012 15.3 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain Apolipoprotein PF01442.13 EDN94470.1 - 0.029 13.8 0.5 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.4 EDN94470.1 - 0.58 10.3 2.8 8.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-H2C2_2 PF13465.1 EDN94471.1 - 5.9e-07 29.4 18.2 9.3e-06 25.6 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN94471.1 - 8.6e-05 22.6 18.3 0.0026 17.9 4.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN94471.1 - 0.00018 21.5 22.1 0.014 15.6 3.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger DUF3401 PF11881.3 EDN94471.1 - 0.028 13.7 0.2 0.25 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3401) zf-C2H2_6 PF13912.1 EDN94471.1 - 0.069 13.0 4.4 0.15 11.9 3.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN94471.1 - 9.7 6.4 10.5 16 5.7 2.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LON PF02190.11 EDN94473.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain Helicase_C PF00271.26 EDN94475.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Mucin PF01456.12 EDN94476.1 - 0.0029 17.3 12.6 0.0029 17.3 8.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 EDN94476.1 - 0.011 13.8 14.3 0.011 13.7 9.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 EDN94476.1 - 1.2 6.9 3.7 1.1 7.0 2.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.1 EDN94476.1 - 10 5.8 7.8 12 5.6 5.4 1.1 1 0 0 1 1 1 0 TMEM154 protein family GAF_2 PF13185.1 EDN94477.1 - 1e-08 35.7 0.0 1.3e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EDN94477.1 - 0.00014 22.0 0.0 0.00019 21.5 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EDN94477.1 - 0.0073 16.4 0.0 0.0092 16.0 0.0 1.1 1 0 0 1 1 1 1 GAF domain DDE_1 PF03184.14 EDN94478.1 - 1.2e-12 47.4 0.0 3.1e-12 46.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN94478.1 - 5.7e-08 32.1 0.0 1.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain S1-like PF14444.1 EDN94478.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 S1-like Glyco_hydro_72 PF03198.9 EDN94479.1 - 2.1e-132 440.9 2.2 2.5e-132 440.6 1.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EDN94479.1 - 7.4e-07 28.3 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EDN94479.1 - 1.1e-05 24.8 0.3 8.1e-05 21.9 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) APH PF01636.18 EDN94481.1 - 3.7e-10 39.9 0.0 6.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN94481.1 - 0.0031 17.1 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HNH_2 PF13391.1 EDN94481.1 - 0.031 14.0 0.1 0.085 12.6 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease GDPD PF03009.12 EDN94484.1 - 3.3e-16 59.5 0.4 4.3e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_2_N PF02837.13 EDN94484.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain GDPD PF03009.12 EDN94485.1 - 2.5e-06 27.1 0.0 3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EDN94485.1 - 0.02 15.0 2.3 0.064 13.4 1.6 1.8 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GCS PF03074.11 EDN94494.1 - 1.8e-155 517.5 0.0 5.5e-155 515.9 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0278 PF08745.6 EDN94494.1 - 0.18 11.0 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 UPF0278 family Ribonuclease_3 PF00636.21 EDN94495.1 - 1.7e-48 163.8 0.0 2.1e-23 82.9 0.0 3.3 3 1 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EDN94495.1 - 6.2e-35 119.9 0.2 5.7e-19 68.3 0.0 3.7 2 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 EDN94495.1 - 1.5e-17 63.6 0.0 4.7e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94495.1 - 8.3e-16 57.6 0.1 3.3e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EDN94495.1 - 5.8e-15 54.8 0.0 2.4e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 EDN94495.1 - 5.5e-09 36.1 0.0 1.8e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EDN94495.1 - 0.00052 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 UvrD-helicase PF00580.16 EDN94495.1 - 0.013 14.7 0.2 1 8.5 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain T2SE PF00437.15 EDN94495.1 - 0.068 12.0 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EDN94495.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein BCDHK_Adom3 PF10436.4 EDN94497.1 - 1.1e-44 151.8 0.0 3.4e-44 150.2 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDN94497.1 - 2e-14 53.2 0.0 5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDN94497.1 - 0.003 17.2 0.6 0.0097 15.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stc1 PF12898.2 EDN94500.1 - 1.1e-23 83.0 8.0 1.7e-23 82.4 5.5 1.3 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.20 EDN94503.1 - 7.7e-59 198.9 0.0 1.1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94503.1 - 2.6e-32 111.9 0.0 8.7e-31 106.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDN94503.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EDN94503.1 - 1.6 8.2 0.0 1.6 8.2 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1387) Fer4_10 PF13237.1 EDN94504.1 - 0.07 12.9 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDN94504.1 - 0.13 12.2 1.0 0.19 11.6 0.7 1.2 1 0 0 1 1 1 0 4Fe-4S binding domain DUF2457 PF10446.4 EDN94505.1 - 0.26 9.9 20.1 0.28 9.8 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 EDN94505.1 - 0.67 9.6 2.9 0.7 9.5 2.0 1.1 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 EDN94505.1 - 0.99 9.6 13.3 1.1 9.5 9.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SGT1 PF07093.6 EDN94505.1 - 1 7.6 5.7 1.1 7.5 4.0 1.0 1 0 0 1 1 1 0 SGT1 protein Sigma70_ner PF04546.8 EDN94505.1 - 1.6 8.3 10.8 1.7 8.1 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region ATG27 PF09451.5 EDN94505.1 - 1.7 7.8 4.6 1.7 7.8 3.2 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Tom22 PF04281.8 EDN94505.1 - 1.8 8.1 8.7 2.1 7.8 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 EDN94505.1 - 2.5 6.0 7.4 2.6 5.9 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.3 EDN94505.1 - 3.8 8.1 15.3 4.5 7.9 10.6 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EDN94505.1 - 4 6.9 16.4 4.9 6.6 11.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 EDN94505.1 - 4.1 7.1 6.7 4.1 7.1 4.7 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2722 PF10846.3 EDN94505.1 - 4.9 6.0 5.9 4.9 6.0 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Utp14 PF04615.8 EDN94505.1 - 5.8 4.9 7.7 6.1 4.8 5.4 1.0 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.7 EDN94505.1 - 7.9 5.6 14.9 8.8 5.4 10.4 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EDN94505.1 - 9 6.6 18.3 11 6.3 12.7 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EDN94505.1 - 9.2 6.0 13.5 11 5.7 9.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal YqfQ PF14181.1 EDN94507.1 - 0.14 12.1 18.2 0.17 11.8 12.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Pox_Ag35 PF03286.9 EDN94507.1 - 0.17 11.3 11.5 0.19 11.2 8.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SprA-related PF12118.3 EDN94507.1 - 0.52 9.5 25.9 0.5 9.6 17.9 1.0 1 0 0 1 1 1 0 SprA-related family FLO_LFY PF01698.11 EDN94507.1 - 0.63 8.8 12.0 0.59 8.9 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 EDN94507.1 - 0.9 8.5 27.0 1.1 8.2 18.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein DARPP-32 PF05395.7 EDN94507.1 - 1.5 8.9 20.1 1.7 8.7 14.0 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Peptidase_U57 PF05582.7 EDN94507.1 - 2 7.2 10.2 1.9 7.4 7.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 RP-C_C PF11800.3 EDN94507.1 - 2.1 7.9 19.1 2.5 7.7 13.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Tim54 PF11711.3 EDN94507.1 - 2.8 6.4 12.3 3 6.3 8.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0565 PF10561.4 EDN94507.1 - 3.2 6.5 18.6 3.3 6.5 12.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Band_3_cyto PF07565.8 EDN94507.1 - 3.2 7.1 17.0 3.3 7.1 11.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Raftlin PF15250.1 EDN94507.1 - 3.4 6.0 13.9 3.2 6.1 9.6 1.1 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.11 EDN94507.1 - 3.9 7.1 13.9 3.9 7.1 9.7 1.1 1 0 0 1 1 1 0 AUX/IAA family Hid1 PF12722.2 EDN94507.1 - 4.1 4.9 23.4 4.3 4.8 16.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpc4 PF05132.9 EDN94507.1 - 4.8 7.1 16.4 6.2 6.8 11.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM60A PF15396.1 EDN94507.1 - 5.4 6.7 11.5 5.2 6.7 8.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hom_end_hint PF05203.11 EDN94507.1 - 5.5 6.6 13.1 5.8 6.5 9.1 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint CPSF100_C PF13299.1 EDN94507.1 - 6.4 6.9 16.2 6.6 6.9 11.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Bul1_N PF04425.7 EDN94507.1 - 7.2 5.0 20.1 7.8 4.9 13.9 1.0 1 0 0 1 1 1 0 Bul1 N terminus FAM176 PF14851.1 EDN94507.1 - 9 5.9 9.1 11 5.6 6.3 1.2 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.11 EDN94507.1 - 9.4 5.5 10.9 8.8 5.6 7.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Pyridoxal_deC PF00282.14 EDN94508.1 - 3e-19 68.7 0.0 4.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDN94508.1 - 9.8e-06 24.5 0.0 3.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN94508.1 - 0.0052 15.8 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SNO PF01174.14 EDN94508.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Glyco_transf_34 PF05637.7 EDN94509.1 - 1.3e-71 240.9 0.0 1.6e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PMI_typeI PF01238.16 EDN94510.1 - 2.7e-71 240.5 0.0 3.2e-70 236.9 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EDN94510.1 - 0.00056 19.3 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EDN94510.1 - 0.0048 16.5 0.0 0.078 12.6 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain RINGv PF12906.2 EDN94511.1 - 1.7e-08 34.3 3.6 8.5e-08 32.1 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EDN94511.1 - 0.016 15.0 5.4 0.07 12.9 1.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EDN94511.1 - 0.074 12.7 0.8 0.69 9.6 0.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 EDN94511.1 - 0.09 12.8 0.5 0.09 12.8 0.4 1.9 2 0 0 2 2 2 0 C1-like domain Proteasome PF00227.21 EDN94512.1 - 3.7e-51 173.1 0.1 3.8e-27 94.8 0.0 2.8 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EDN94512.1 - 1.8e-11 43.1 0.3 4e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HTH_CodY PF08222.6 EDN94512.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain RCC1_2 PF13540.1 EDN94513.1 - 5.4e-11 41.7 3.5 3.3e-05 23.3 0.0 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EDN94513.1 - 7.9e-08 32.3 8.1 0.014 15.6 0.0 4.5 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EDN94513.1 - 0.067 12.6 0.4 0.17 11.4 0.1 1.9 2 1 0 2 2 2 0 Putative carbohydrate binding domain HSP70 PF00012.15 EDN94514.1 - 7.9e-11 40.5 0.1 2.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein DUF655 PF04919.7 EDN94515.1 - 0.016 14.8 0.1 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) TMF_TATA_bd PF12325.3 EDN94518.1 - 0.0046 16.6 0.4 0.017 14.8 0.2 1.9 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Acyl-ACP_TE PF01643.12 EDN94518.1 - 0.029 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase Macoilin PF09726.4 EDN94518.1 - 0.03 12.6 14.1 0.041 12.1 9.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Metal_resist PF13801.1 EDN94518.1 - 0.28 11.1 1.8 0.34 10.9 0.4 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF605 PF04652.11 EDN94518.1 - 1 8.7 33.0 1.4 8.2 22.9 1.2 1 0 0 1 1 1 0 Vta1 like MDFI PF15316.1 EDN94518.1 - 1.3 8.9 5.1 2.8 7.8 3.5 1.6 1 0 0 1 1 1 0 MyoD family inhibitor AKAP7_NLS PF10469.4 EDN94519.1 - 2.7e-14 53.3 0.3 1e-12 48.2 0.2 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.18 EDN94520.1 - 8.8e-13 48.0 0.3 1.4e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Hpt domain DUF2593 PF10767.4 EDN94521.1 - 0.084 12.5 0.2 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Collagen_bind_2 PF12904.2 EDN94522.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase CsbD PF05532.7 EDN94523.1 - 4.6e-10 39.0 19.4 4.9e-08 32.5 2.8 3.3 2 1 1 3 3 3 2 CsbD-like Apo-CIII PF05778.7 EDN94523.1 - 0.17 11.3 0.6 0.37 10.1 0.4 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) DUF1601 PF07671.6 EDN94524.1 - 0.083 12.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) A2M PF00207.17 EDN94524.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin family Peptidase_M49 PF03571.10 EDN94525.1 - 7.9e-49 166.1 0.1 1.8e-47 161.7 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M49 Oxysterol_BP PF01237.13 EDN94526.1 - 6.3e-72 242.0 2.0 1.3e-70 237.7 1.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein IncA PF04156.9 EDN94527.1 - 4.7 6.7 6.7 1.1 8.8 1.9 1.7 2 0 0 2 2 2 0 IncA protein Sugar_tr PF00083.19 EDN94529.1 - 4.7e-101 338.5 19.0 8.5e-101 337.7 13.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN94529.1 - 2e-24 85.9 32.0 2e-24 85.9 22.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Trep_Strep PF09605.5 EDN94529.1 - 0.015 14.9 3.8 0.015 14.9 2.6 3.0 5 0 0 5 5 5 0 Hypothetical bacterial integral membrane protein (Trep_Strep) JmjC PF02373.17 EDN94530.1 - 7.8e-06 26.1 1.8 2e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EDN94530.1 - 5.7e-05 23.1 11.5 5.7e-05 23.1 8.0 2.8 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EDN94530.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Cupin domain DDE_1 PF03184.14 EDN94531.1 - 9.1e-63 211.2 0.0 1.7e-62 210.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease UbiA PF01040.13 EDN94531.1 - 3.9e-31 108.2 21.1 5.7e-31 107.6 14.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HTH_psq PF05225.11 EDN94531.1 - 4.4e-15 54.9 0.0 8.6e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN94531.1 - 1.7e-11 43.7 0.1 3.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN94531.1 - 1.7e-08 34.3 0.0 9e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDN94531.1 - 0.05 13.6 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN94531.1 - 0.096 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Lsr2 PF11774.3 EDN94531.1 - 0.35 10.7 1.3 0.95 9.4 0.1 2.2 2 0 0 2 2 2 0 Lsr2 MARVEL PF01284.18 EDN94532.1 - 1.1e-24 86.8 15.3 1.3e-24 86.6 10.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain TctB PF07331.6 EDN94532.1 - 0.7 9.5 10.8 7.3 6.2 7.5 2.1 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2304 PF10066.4 EDN94532.1 - 1.2 9.0 5.6 0.45 10.3 2.3 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF4191 PF13829.1 EDN94532.1 - 1.2 8.1 3.7 2 7.4 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4293 PF14126.1 EDN94532.1 - 2.6 7.9 9.4 1.9 8.4 4.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Syd PF07348.7 EDN94533.1 - 0.085 12.1 0.3 0.1 11.9 0.2 1.1 1 0 0 1 1 1 0 Syd protein (SUKH-2) eIF-5_eIF-2B PF01873.12 EDN94534.1 - 8.7e-46 154.6 0.7 1.3e-45 154.0 0.5 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.7 EDN94534.1 - 0.62 9.5 3.1 0.54 9.7 0.8 2.0 2 0 0 2 2 2 0 HypF finger AIM24 PF01987.12 EDN94535.1 - 4.7e-46 156.9 0.2 6.2e-46 156.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 APH PF01636.18 EDN94536.1 - 3.4e-08 33.5 0.0 3.6e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DEAD PF00270.24 EDN94537.1 - 5.7e-18 64.9 0.0 1.1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94537.1 - 8.5e-08 31.9 0.1 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN94537.1 - 1.3e-07 31.6 0.0 1.5e-06 28.1 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN94537.1 - 0.29 10.3 0.0 0.55 9.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sugar_tr PF00083.19 EDN94539.1 - 8.4e-105 350.9 26.0 9.6e-105 350.7 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN94539.1 - 6.9e-22 77.6 38.1 1.1e-15 57.1 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EDN94539.1 - 0.00029 19.0 6.2 0.0007 17.8 1.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector DUF1228 PF06779.9 EDN94539.1 - 0.00039 20.3 4.7 0.087 12.8 0.2 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) TylF PF05711.6 EDN94541.1 - 8.6e-11 41.3 0.0 4.1e-08 32.6 0.0 2.2 1 1 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 EDN94541.1 - 4.9e-08 33.7 0.0 8.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_17 PF12692.2 EDN94541.1 - 7.7e-05 22.4 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 2 S-adenosyl-L-methionine methyltransferase DUF3431 PF11913.3 EDN94543.1 - 6.3e-14 51.9 0.2 1.6e-13 50.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3435 PF11917.3 EDN94544.1 - 1.1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-U1 PF06220.7 EDN94545.1 - 6.7e-18 63.9 3.1 9.6e-18 63.4 2.1 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EDN94545.1 - 0.17 12.0 2.3 0.41 10.8 1.6 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EMP24_GP25L PF01105.19 EDN94546.1 - 3e-44 150.9 0.0 3.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 EDN94546.1 - 0.025 12.7 0.3 0.032 12.4 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Nup54 PF13874.1 EDN94546.1 - 0.059 13.0 0.4 0.087 12.4 0.3 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Pkinase PF00069.20 EDN94548.1 - 1.1e-07 31.3 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94548.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN94548.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDN94548.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Gln-synt_C PF00120.19 EDN94550.1 - 2.9e-61 206.9 0.0 3.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EDN94550.1 - 3e-19 68.3 0.0 6.1e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Pkinase PF00069.20 EDN94552.1 - 4.2e-76 255.5 0.0 5.8e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94552.1 - 8.7e-39 133.1 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EDN94552.1 - 1.8e-13 50.4 0.1 4.2e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EDN94552.1 - 5.6e-08 32.0 0.0 1.9e-07 30.3 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDN94552.1 - 5.4e-05 22.6 0.5 0.00013 21.4 0.3 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EDN94552.1 - 0.00091 17.8 0.2 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EDN94552.1 - 0.038 13.0 0.1 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN94552.1 - 0.059 13.0 3.0 0.42 10.3 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RVT_1 PF00078.22 EDN94553.1 - 2.7e-24 85.7 0.1 5.4e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN94553.1 - 2.3e-17 63.2 0.0 5.1e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN94553.1 - 2.8e-07 30.0 0.8 8.1e-07 28.6 0.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN94553.1 - 0.00012 21.4 0.0 0.00028 20.2 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Med1 PF10744.4 EDN94555.1 - 1.3e-89 300.6 0.0 1.9e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 COesterase PF00135.23 EDN94558.1 - 5.7e-92 309.1 0.0 1.1e-91 308.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN94558.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DDE_1 PF03184.14 EDN94559.1 - 5e-22 78.1 0.3 4.8e-21 74.9 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN94559.1 - 0.09 12.6 0.0 0.31 10.8 0.0 2.0 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain CHB_HEX_C PF03174.8 EDN94560.1 - 0.012 15.4 5.5 0.017 14.9 3.8 1.2 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Phageshock_PspD PF09584.5 EDN94560.1 - 0.04 13.6 0.2 0.071 12.8 0.2 1.3 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) CHB_HEX_C_1 PF13290.1 EDN94560.1 - 0.084 12.6 4.9 0.12 12.1 3.4 1.3 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF3328 PF11807.3 EDN94567.1 - 3.3e-36 124.9 1.5 4.8e-36 124.4 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribonuc_L-PSP PF01042.16 EDN94570.1 - 1.4e-26 92.6 0.0 2.3e-26 91.9 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP His_Phos_1 PF00300.17 EDN94571.1 - 3.6e-10 40.1 0.1 1.2e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Integrin_b_cyt PF08725.6 EDN94571.1 - 0.022 14.1 0.9 0.051 12.9 0.6 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain DUF3169 PF11368.3 EDN94572.1 - 0.012 14.8 1.4 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MARVEL PF01284.18 EDN94572.1 - 0.028 14.2 11.8 0.04 13.7 8.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain Antirestrict PF03230.8 EDN94572.1 - 0.041 13.8 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 Antirestriction protein DUF1129 PF06570.6 EDN94572.1 - 0.13 11.6 2.8 0.22 10.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) NfeD PF01957.13 EDN94572.1 - 1.3 9.1 4.7 0.94 9.6 2.0 1.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2975 PF11188.3 EDN94572.1 - 8.6 6.0 9.6 0.42 10.3 1.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Fungal_trans_2 PF11951.3 EDN94573.1 - 1.4e-05 23.8 0.0 3.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN94573.1 - 0.0071 16.2 4.2 0.014 15.2 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.8 EDN94580.1 - 0.24 11.1 2.3 0.36 10.5 1.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like SUR7 PF06687.7 EDN94582.1 - 2.1e-22 79.7 14.1 2.7e-22 79.4 9.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EDN94582.1 - 0.0006 19.5 9.6 0.0006 19.5 6.6 2.3 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Glycophorin_A PF01102.13 EDN94582.1 - 0.00067 19.4 0.4 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 Glycophorin A GpcrRhopsn4 PF10192.4 EDN94582.1 - 0.001 18.2 1.5 0.001 18.2 1.0 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain PLAC8 PF04749.12 EDN94582.1 - 0.27 11.8 2.4 0.49 10.9 0.3 2.2 1 1 1 2 2 2 0 PLAC8 family DUF2231 PF09990.4 EDN94582.1 - 1.2 9.5 0.1 1.2 9.5 0.0 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2231) VIT1 PF01988.14 EDN94582.1 - 2.7 7.4 16.0 0.044 13.2 6.1 1.7 2 0 0 2 2 2 0 VIT family DUF3446 PF11928.3 EDN94583.1 - 7.6 6.8 10.0 3.7 7.8 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3446) AA_permease PF00324.16 EDN94587.1 - 4.2e-140 467.2 39.9 5.1e-140 466.9 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN94587.1 - 1.4e-42 145.7 45.9 1.8e-42 145.4 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease MOZART2 PF12926.2 EDN94587.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF575 PF04746.7 EDN94587.1 - 0.78 9.8 2.9 2.5 8.1 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF575) zf-C2H2_4 PF13894.1 EDN94588.1 - 7.3e-08 32.2 12.1 0.063 13.6 0.1 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger Raptor_N PF14538.1 EDN94588.1 - 0.0014 18.4 0.0 0.0057 16.5 0.0 2.0 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain zf-H2C2_2 PF13465.1 EDN94588.1 - 0.0027 17.9 1.8 3.9 7.9 0.0 3.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-TRAF PF02176.13 EDN94588.1 - 0.015 15.6 0.6 0.058 13.7 0.4 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2 PF00096.21 EDN94588.1 - 0.35 11.3 21.4 0.32 11.4 0.6 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EDN94588.1 - 9.2 6.7 8.2 76 3.8 0.1 4.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Pkinase PF00069.20 EDN94589.1 - 2.2e-26 92.5 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94589.1 - 3.2e-06 26.4 0.0 2.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase WW PF00397.21 EDN94589.1 - 0.075 12.9 6.1 6.9 6.6 0.0 2.9 2 1 0 2 2 2 0 WW domain Coatomer_E PF04733.9 EDN94591.1 - 4.5e-65 219.7 7.2 5.1e-65 219.5 5.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EDN94591.1 - 8.2e-11 42.0 19.1 0.001 19.3 0.3 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN94591.1 - 2.1e-10 40.2 14.1 9.7e-06 25.7 0.1 6.0 3 1 2 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN94591.1 - 1.2e-08 35.0 1.9 0.065 13.3 0.0 3.7 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EDN94591.1 - 1.6e-08 34.0 1.8 0.0066 16.0 0.0 4.5 3 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EDN94591.1 - 1.1e-07 32.3 10.3 0.00092 19.8 0.0 4.5 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN94591.1 - 1.7e-05 24.1 4.4 0.1 12.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN94591.1 - 2.4e-05 24.1 10.3 0.93 9.4 0.2 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDN94591.1 - 5e-05 22.9 14.7 0.0011 18.7 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN94591.1 - 0.00023 21.1 0.3 9.1 6.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN94591.1 - 0.00051 19.6 0.1 0.032 14.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN94591.1 - 0.0013 18.4 7.1 0.38 10.6 0.1 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat Type_III_YscG PF09477.5 EDN94591.1 - 0.0098 15.9 6.9 10 6.2 0.1 3.7 1 1 4 5 5 5 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 EDN94591.1 - 0.019 15.3 1.9 0.019 15.3 1.3 6.1 7 1 1 8 8 7 0 Tetratricopeptide repeat KorB PF08535.5 EDN94591.1 - 0.045 13.9 0.3 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 KorB domain TPR_10 PF13374.1 EDN94591.1 - 0.081 12.8 12.3 3.7 7.5 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN94591.1 - 0.43 10.4 4.0 0.71 9.7 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN94591.1 - 0.48 10.9 6.1 16 6.2 0.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EDN94591.1 - 4.3 7.2 8.7 0.94 9.3 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EDN94591.1 - 5.3 7.2 9.4 5.2 7.2 0.4 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat HAD PF12710.2 EDN94592.1 - 6.6e-10 39.4 0.0 9.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDN94592.1 - 0.0069 15.5 0.0 0.04 13.0 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 EDN94592.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EDN94592.1 - 0.028 14.8 0.1 0.22 11.9 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fumerase PF05681.9 EDN94593.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Cyt-b5 PF00173.23 EDN94594.1 - 0.035 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 EDN94596.1 - 1.6e-30 106.0 47.1 3.1e-30 105.0 32.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN94596.1 - 1.5e-18 66.3 15.9 2e-18 65.9 11.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.1 EDN94596.1 - 0.013 15.1 10.8 0.56 9.9 1.5 3.3 2 1 0 2 2 2 0 YrhK-like protein Aminotran_1_2 PF00155.16 EDN94597.1 - 2.9e-07 29.7 0.1 5.5e-05 22.2 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Acyl_transf_1 PF00698.16 EDN94600.1 - 2.4e-60 204.5 0.0 4.4e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EDN94600.1 - 4.6e-54 182.8 0.1 9.4e-54 181.8 0.0 1.6 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 EDN94600.1 - 9.2e-42 143.2 0.3 4e-29 101.8 0.0 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EDN94600.1 - 2.1e-41 141.6 0.0 5.5e-41 140.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDN94600.1 - 8.3e-31 106.3 0.0 3e-30 104.5 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EDN94600.1 - 5.6e-17 61.8 0.0 1.3e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EDN94600.1 - 7.3e-09 35.2 0.0 2.5e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EDN94600.1 - 6e-08 32.8 0.1 2.2e-07 31.0 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EDN94600.1 - 1.9e-07 30.9 0.0 6.1e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN94600.1 - 2.8e-06 27.7 0.0 2e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EDN94600.1 - 3e-06 26.9 0.1 7.5e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EDN94600.1 - 3.9e-06 26.5 0.0 2e-05 24.2 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN94600.1 - 0.00052 20.4 0.0 0.0037 17.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EDN94600.1 - 0.0021 18.9 0.0 0.02 15.7 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 EDN94600.1 - 0.0033 16.1 0.0 0.0057 15.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PS_Dcarbxylase PF02666.10 EDN94601.1 - 1.7e-53 180.9 0.0 2.5e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EDN94601.1 - 1.8e-37 127.0 0.2 9.8e-19 66.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EDN94601.1 - 0.00043 20.3 0.0 0.0016 18.5 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN94601.1 - 0.0092 15.2 0.1 0.031 13.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EDN94601.1 - 0.019 14.7 0.7 0.11 12.3 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain E1-E2_ATPase PF00122.15 EDN94603.1 - 3e-63 212.9 3.8 7.1e-63 211.7 2.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN94603.1 - 6.7e-35 120.2 4.1 6.7e-35 120.2 2.9 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN94603.1 - 4.3e-29 102.4 0.0 1.3e-27 97.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN94603.1 - 1.4e-21 76.2 0.0 3.5e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDN94603.1 - 4.6e-13 48.4 0.2 1.2e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDN94603.1 - 1.4e-12 48.2 0.0 3.6e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN94603.1 - 4.6e-06 26.3 3.7 0.014 15.0 0.4 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase KR PF08659.5 EDN94603.1 - 0.06 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.2 EDN94604.1 - 2e-28 98.5 0.6 4.8e-09 36.4 0.7 4.6 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN94604.1 - 2.6e-25 86.9 1.5 8.2e-05 22.2 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EDN94604.1 - 3.7e-21 74.6 0.5 0.00014 22.0 0.0 6.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN94604.1 - 1.3e-19 70.2 0.3 0.00053 20.4 0.0 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN94604.1 - 3.8e-15 54.4 0.6 0.1 12.9 0.1 7.3 7 0 0 7 7 7 3 Ankyrin repeat CorA PF01544.13 EDN94604.1 - 7e-11 41.6 0.4 7e-11 41.6 0.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HisKA PF00512.20 EDN94604.1 - 0.13 12.2 1.0 0.91 9.5 0.7 2.3 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Wzy_C PF04932.10 EDN94605.1 - 0.17 11.6 7.4 0.2 11.4 5.1 1.3 1 0 0 1 1 1 0 O-Antigen ligase Claudin_2 PF13903.1 EDN94605.1 - 0.38 10.4 8.8 0.53 9.9 6.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CbiQ PF02361.11 EDN94605.1 - 0.62 9.5 9.4 1 8.9 6.5 1.4 1 0 0 1 1 1 0 Cobalt transport protein DUF3487 PF11990.3 EDN94605.1 - 2.1 7.7 10.1 3.1 7.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF898 PF05987.8 EDN94605.1 - 2.4 6.9 10.3 2.6 6.8 7.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) O-antigen_lig PF13425.1 EDN94605.1 - 2.6 8.0 10.9 3.2 7.7 7.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Lipase_GDSL PF00657.17 EDN94608.1 - 3.7e-07 30.2 0.5 5.6e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDN94608.1 - 1.1e-05 25.7 0.1 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-C2H2_4 PF13894.1 EDN94611.1 - 1.3e-05 25.1 20.9 0.022 15.0 1.4 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN94611.1 - 0.0069 16.6 2.2 0.0069 16.6 1.6 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type C1_4 PF07975.7 EDN94611.1 - 0.0097 15.8 0.3 0.0097 15.8 0.2 1.9 2 0 0 2 2 2 1 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EDN94611.1 - 0.018 14.9 0.8 0.073 13.0 0.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC PF01530.13 EDN94611.1 - 0.18 11.5 2.2 8 6.2 0.0 2.9 3 0 0 3 3 3 0 Zinc finger, C2HC type zf-H2C2_2 PF13465.1 EDN94611.1 - 2.2 8.7 15.7 1.7 9.1 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain GET2 PF08690.5 EDN94612.1 - 9.2e-06 25.1 8.4 0.0015 17.8 0.2 3.2 2 1 0 2 2 2 2 GET complex subunit GET2 WD40 PF00400.27 EDN94613.1 - 3.3e-16 58.4 1.2 0.00035 20.3 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Sec16_C PF12931.2 EDN94613.1 - 6e-07 29.4 0.4 2.9e-06 27.2 0.1 2.2 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.6 EDN94613.1 - 4.4e-06 26.5 10.7 4.4e-06 26.5 7.4 3.4 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) RRM_1 PF00076.17 EDN94614.1 - 2.9e-17 62.0 0.0 4.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94614.1 - 3.9e-12 45.9 0.0 7.9e-12 44.9 0.0 1.5 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN94614.1 - 1.7e-07 30.9 0.0 4.1e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B12D PF06522.6 EDN94615.1 - 0.00081 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 EDN94616.1 - 1.1e-20 73.3 4.0 1.4e-20 73.1 2.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EDN94616.1 - 0.0064 15.8 0.6 0.011 15.1 0.4 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EDN94616.1 - 0.079 12.8 0.6 0.21 11.5 0.4 1.8 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.21 EDN94616.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UPF0203 PF05254.7 EDN94616.1 - 1.2 8.9 4.7 2.2 8.1 1.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Peptidase_M20 PF01546.23 EDN94617.1 - 0.0043 16.5 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN94617.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain Telomere_Sde2 PF13019.1 EDN94618.1 - 2.5e-24 85.8 6.2 4.7e-24 84.8 4.3 1.5 1 0 0 1 1 1 1 Telomere stability and silencing DUF605 PF04652.11 EDN94618.1 - 0.055 12.8 14.4 0.075 12.4 10.0 1.1 1 0 0 1 1 1 0 Vta1 like LacI PF00356.16 EDN94618.1 - 0.087 12.4 1.6 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Nop14 PF04147.7 EDN94618.1 - 0.85 7.4 30.8 1.4 6.7 21.3 1.3 1 1 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EDN94618.1 - 3.7 6.7 24.5 5.8 6.0 17.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 EDN94618.1 - 5.5 4.5 5.9 6.7 4.2 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TAF4 PF05236.9 EDN94618.1 - 6.5 5.9 16.3 0.013 14.8 4.2 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family S10_plectin PF03501.10 EDN94619.1 - 9e-39 131.2 0.3 1.1e-38 130.9 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 EDN94621.1 - 3.4e-29 100.7 0.2 1e-28 99.2 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN94621.1 - 2.9e-17 62.4 0.0 5.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN94621.1 - 2.2e-05 25.3 0.0 3.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EDN94621.1 - 0.016 14.2 0.6 0.026 13.6 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 EDN94621.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EDN94621.1 - 0.037 14.0 0.2 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EDN94621.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2318 PF10080.4 EDN94621.1 - 0.078 12.7 1.2 15 5.3 0.5 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) ATE_C PF04377.10 EDN94622.1 - 9.9e-44 148.4 0.8 1.8e-43 147.6 0.5 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EDN94622.1 - 6.2e-05 22.7 0.2 0.00015 21.5 0.2 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.23 EDN94624.1 - 4.3e-17 62.0 1.0 5.1e-17 61.7 0.7 1.0 1 0 0 1 1 1 1 NUDIX domain LSM PF01423.17 EDN94626.1 - 7.1e-09 35.0 0.0 1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain RasGEF PF00617.14 EDN94628.1 - 4.1e-45 153.8 0.4 7.1e-45 153.0 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDN94628.1 - 1.3e-13 50.9 0.0 4.2e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EDN94628.1 - 3.6e-13 50.0 0.0 1.7e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EDN94628.1 - 5.3e-05 22.6 0.2 0.00065 19.1 0.0 2.5 2 1 0 2 2 2 1 Ras family AAA_29 PF13555.1 EDN94628.1 - 0.025 14.0 0.0 0.091 12.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN94628.1 - 0.029 13.7 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EDN94628.1 - 0.038 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EDN94628.1 - 0.087 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 EDN94628.1 - 0.089 12.7 0.2 0.29 11.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EDN94628.1 - 0.15 12.8 0.0 0.6 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDN94628.1 - 0.22 11.6 0.8 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF3578 PF12102.3 EDN94631.1 - 0.028 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) Rota_NSP3 PF01665.11 EDN94631.1 - 0.16 10.8 0.4 0.26 10.2 0.3 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 HEAT_2 PF13646.1 EDN94632.1 - 0.058 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 HEAT repeats Nfu_N PF08712.6 EDN94633.1 - 3.1e-29 100.4 0.0 1.5e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EDN94633.1 - 3e-22 78.1 0.2 5.7e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 EDN94636.1 - 2.7e-30 104.1 0.8 4.2e-30 103.5 0.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region ScpA_ScpB PF02616.9 EDN94637.1 - 5.2 6.5 10.6 0.52 9.8 4.1 1.6 1 1 1 2 2 2 0 ScpA/B protein Ribosomal_L15e PF00827.12 EDN94638.1 - 1.2e-91 305.5 9.2 1.3e-91 305.3 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.20 EDN94639.1 - 1.1e-73 248.1 0.0 1.8e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 EDN94639.1 - 0.012 15.3 0.9 0.025 14.2 0.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) L51_S25_CI-B8 PF05047.11 EDN94641.1 - 7.3e-18 64.0 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.18 EDN94642.1 - 0.00015 21.7 0.0 0.00077 19.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Mnd1 PF03962.10 EDN94644.1 - 5.6 6.5 8.4 4.7 6.8 3.5 2.1 1 1 1 2 2 2 0 Mnd1 family Ribosomal_L7Ae PF01248.21 EDN94645.1 - 9.8e-22 76.2 0.4 9.8e-22 76.2 0.3 2.3 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDN94645.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 UcrQ PF02939.11 EDN94646.1 - 6.5e-29 99.5 0.2 8.1e-29 99.2 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EDN94647.1 - 1.8e-25 89.8 6.5 2.5e-25 89.4 4.2 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Trp_DMAT PF11991.3 EDN94650.1 - 2.8e-106 355.7 0.0 3.9e-106 355.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Rft-1 PF04506.8 EDN94651.1 - 4.3e-89 299.3 7.6 5.4e-89 299.0 5.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EDN94651.1 - 3.8e-06 26.3 9.8 3.8e-06 26.3 6.8 2.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein DEAD PF00270.24 EDN94652.1 - 1.2e-49 168.0 0.0 8e-48 162.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94652.1 - 4.7e-30 103.2 0.0 1.6e-28 98.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN94652.1 - 1.1e-08 35.1 0.1 6.2e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EDN94652.1 - 0.0029 16.9 0.0 0.0067 15.7 0.0 1.8 1 1 0 1 1 1 1 SecA DEAD-like domain DUF1253 PF06862.7 EDN94652.1 - 0.0069 14.8 0.0 0.065 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EDN94652.1 - 0.0094 16.1 0.0 0.036 14.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain CMS1 PF14617.1 EDN94652.1 - 0.011 14.8 0.0 0.011 14.8 0.0 3.1 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF563 PF04577.9 EDN94652.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF563) NifU_N PF01592.11 EDN94653.1 - 5.1e-51 171.8 0.0 6.8e-51 171.4 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 EDN94654.1 - 2e-41 141.8 0.0 3e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EDN94654.1 - 3.2e-24 84.0 1.4 1.7e-11 43.6 0.4 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.14 EDN94654.1 - 2.5e-21 75.5 12.0 3.2e-18 65.5 2.5 2.9 2 1 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EDN94654.1 - 1.2e-20 74.1 0.0 4.3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TerY-C PF15616.1 EDN94654.1 - 0.014 15.3 1.4 0.85 9.5 0.4 2.7 2 0 0 2 2 2 0 TerY-C metal binding domain Prim_Zn_Ribbon PF08273.7 EDN94654.1 - 0.077 13.0 9.4 0.11 12.6 0.2 4.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase UBA_4 PF14555.1 EDN94654.1 - 0.084 12.4 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain DUF2180 PF09947.4 EDN94654.1 - 1.6 8.5 8.5 3.4 7.4 0.3 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Peptidase_M20 PF01546.23 EDN94655.1 - 1.3e-31 109.6 0.0 2.2e-31 108.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN94655.1 - 1.1e-16 60.4 0.0 1.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-C2H2 PF00096.21 EDN94658.1 - 7.3e-09 35.4 13.7 0.00027 21.1 3.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN94658.1 - 3e-07 30.3 11.5 0.00026 21.1 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN94658.1 - 0.00089 19.0 2.0 0.0023 17.7 0.9 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN94658.1 - 0.018 15.2 13.1 0.63 10.4 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDN94658.1 - 0.04 14.0 2.0 0.27 11.4 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN94658.1 - 0.046 13.9 1.6 0.24 11.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type cNMP_binding PF00027.24 EDN94662.1 - 3.8e-39 132.3 0.0 1.5e-19 69.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.6 EDN94663.1 - 5e-36 124.2 0.0 5.5e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EDN94664.1 - 1.3e-280 932.1 0.0 1.5e-280 931.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase RNA_pol_Rpb1_1 PF04997.7 EDN94665.1 - 4.1e-89 299.1 0.1 7.2e-89 298.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EDN94665.1 - 1.1e-85 287.2 0.1 2.5e-85 286.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDN94665.1 - 2.6e-69 232.3 0.0 6.9e-69 231.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDN94665.1 - 9.9e-39 132.6 0.0 2.3e-38 131.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDN94665.1 - 2.9e-26 91.3 0.1 1.2e-25 89.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Transketolase_N PF00456.16 EDN94665.1 - 0.042 12.6 0.0 0.094 11.5 0.0 1.5 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain NIF PF03031.13 EDN94666.1 - 1e-53 181.2 0.0 1.5e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 EDN94667.1 - 6.3e-58 196.0 8.4 2.2e-54 184.3 5.8 2.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2493 PF10686.4 EDN94667.1 - 0.0013 18.1 0.3 0.14 11.7 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2493) Cep57_MT_bd PF06657.8 EDN94667.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4646 PF15496.1 EDN94669.1 - 0.00041 20.3 0.2 0.003 17.6 0.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF972 PF06156.8 EDN94669.1 - 0.19 12.1 17.2 13 6.1 3.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF972) CAF-1_p150 PF11600.3 EDN94669.1 - 0.42 9.9 32.1 0.18 11.1 13.7 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF342 PF03961.8 EDN94669.1 - 0.81 8.0 17.2 0.15 10.4 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PA26 PF04636.8 EDN94669.1 - 8.6 4.9 12.7 1 7.9 2.3 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) adh_short PF00106.20 EDN94670.1 - 1.3e-20 73.9 0.3 5.2e-20 72.0 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN94670.1 - 5.7e-18 65.5 0.4 3.6e-17 62.9 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN94670.1 - 2.4e-10 40.3 1.7 1.2e-08 34.8 1.2 2.1 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EDN94670.1 - 0.034 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDN94670.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EDN94670.1 - 0.074 12.6 0.6 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EDN94670.1 - 0.078 13.3 0.4 0.29 11.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.5 EDN94670.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HI0933_like PF03486.9 EDN94670.1 - 0.11 10.9 0.8 0.25 9.7 0.5 1.7 1 1 1 2 2 2 0 HI0933-like protein ADH_zinc_N PF00107.21 EDN94670.1 - 0.13 11.7 0.3 0.33 10.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glutaredoxin PF00462.19 EDN94671.1 - 1.5e-16 60.1 0.0 2.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.14 EDN94672.1 - 1.8e-38 131.1 0.2 4.4e-38 129.8 0.0 1.8 2 0 0 2 2 2 1 Flavoprotein Aminotran_4 PF01063.14 EDN94673.1 - 8.2e-27 94.1 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 EDN94674.1 - 4.5e-18 65.7 0.0 3.9e-14 52.9 0.0 3.4 2 1 0 2 2 2 2 Cytidylyltransferase WD40 PF00400.27 EDN94678.1 - 1.8e-25 87.8 2.0 2.9e-05 23.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_S10 PF00450.17 EDN94679.1 - 3.1e-109 365.9 0.0 3.7e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDN94679.1 - 0.0019 18.0 0.0 0.015 15.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_Me_trans PF04252.8 EDN94680.1 - 1.3e-46 158.4 0.0 1.6e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 EDN94681.1 - 2.1e-20 72.4 0.0 3.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.8 EDN94682.1 - 3.5e-128 427.5 0.0 4e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 EDN94683.1 - 5.4e-113 377.7 1.0 6.4e-113 377.4 0.7 1.0 1 0 0 1 1 1 1 ICE2 TctB PF07331.6 EDN94683.1 - 3.6 7.2 14.1 0.059 13.0 1.5 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family SAP PF02037.22 EDN94685.1 - 0.022 14.2 0.1 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 SAP domain CIAPIN1 PF05093.8 EDN94686.1 - 3.7e-35 120.0 4.3 5.9e-35 119.3 3.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HABP4_PAI-RBP1 PF04774.10 EDN94687.1 - 1 9.9 6.9 2.3 8.7 4.8 1.7 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family adh_short PF00106.20 EDN94688.1 - 3e-27 95.5 0.0 4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN94688.1 - 3.2e-14 52.9 0.0 4.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN94688.1 - 6.8e-12 45.6 0.0 9.2e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN94688.1 - 0.00097 18.6 0.0 0.0027 17.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EDN94689.1 - 8.1e-81 271.5 0.0 1.1e-80 271.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN94689.1 - 1e-42 145.8 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EDN94689.1 - 5.3e-08 32.5 0.0 1.3e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN94689.1 - 3.6e-05 23.9 0.1 9.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDN94689.1 - 0.0048 17.8 0.0 0.012 16.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EDN94689.1 - 0.012 14.3 0.1 0.53 8.9 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family P5CR_dimer PF14748.1 EDN94690.1 - 3.4e-28 97.7 1.5 6.1e-28 96.9 1.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDN94690.1 - 3.3e-06 27.4 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF4470 PF14737.1 EDN94690.1 - 0.0094 15.6 0.0 0.29 10.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) ADH_N PF08240.7 EDN94691.1 - 2.5e-23 81.8 3.4 4.1e-23 81.2 2.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN94691.1 - 2.1e-17 62.8 0.0 3.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN94691.1 - 0.00059 19.0 0.0 0.00093 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDN94691.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF4241 PF14025.1 EDN94691.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4241) GFO_IDH_MocA PF01408.17 EDN94691.1 - 0.092 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 EDN94692.1 - 8.3e-54 182.6 49.3 8.2e-39 133.3 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN94692.1 - 1.8e-08 33.3 28.2 2.8e-06 26.2 2.7 4.0 3 1 0 4 4 4 3 Sugar (and other) transporter BT1 PF03092.11 EDN94692.1 - 2.7e-05 23.0 1.6 0.0025 16.5 0.0 3.5 1 1 0 3 3 3 1 BT1 family MFS_2 PF13347.1 EDN94692.1 - 0.0037 15.7 28.3 0.0046 15.4 0.4 3.8 3 1 1 4 4 4 3 MFS/sugar transport protein Mem_trans PF03547.13 EDN94692.1 - 0.0073 14.6 1.5 0.015 13.5 0.0 2.2 1 1 1 2 2 2 1 Membrane transport protein MFS_1_like PF12832.2 EDN94692.1 - 0.2 11.4 4.7 0.26 11.0 0.1 3.5 4 2 1 5 5 5 0 MFS_1 like family OATP PF03137.15 EDN94692.1 - 1.9 6.4 8.4 0.24 9.4 1.5 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FA_hydroxylase PF04116.8 EDN94693.1 - 2.2e-18 66.7 6.3 2.2e-18 66.7 4.3 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HAUS2 PF15003.1 EDN94694.1 - 0.04 12.9 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 G-patch PF01585.18 EDN94696.1 - 5.1e-11 42.1 2.7 9.9e-11 41.2 1.8 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EDN94696.1 - 9.4e-08 31.7 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN94696.1 - 5.5e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94696.1 - 0.004 17.1 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EDN94697.1 - 5.9e-84 281.8 0.0 8.2e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN94697.1 - 4.9e-16 59.4 0.4 1.3e-15 58.0 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EDN94697.1 - 0.00085 17.9 0.0 0.0041 15.6 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.5 EDN94697.1 - 0.077 12.7 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 RTX C-terminal domain Ecm33 PF12454.3 EDN94698.1 - 1.9e-13 50.0 5.6 1.9e-13 50.0 3.9 2.9 4 0 0 4 4 4 1 GPI-anchored cell wall organization protein Asp_decarbox PF02261.11 EDN94698.1 - 0.021 14.3 0.2 0.057 13.0 0.1 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase DUF4522 PF15022.1 EDN94698.1 - 0.072 12.8 0.1 6.7 6.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4522) Pilus_PilP PF11356.3 EDN94698.1 - 0.26 11.5 2.9 0.67 10.2 0.5 2.6 2 0 0 2 2 2 0 Type IV pilus biogenesis HhH-GPD PF00730.20 EDN94700.1 - 7e-16 58.4 0.0 1.6e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 EDN94701.1 - 2.7e-111 371.0 0.0 3.3e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EDN94701.1 - 0.018 14.7 0.2 0.98 9.0 0.1 2.8 2 1 0 2 2 2 0 Glycosyl transferase family 2 UCR_14kD PF02271.11 EDN94702.1 - 5.3e-29 100.0 0.6 3.8e-25 87.6 0.1 2.0 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EDN94703.1 - 6.2e-68 224.5 6.5 1.1e-23 82.7 0.2 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein T2SM PF04612.7 EDN94704.1 - 0.092 12.5 1.7 0.12 12.1 0.8 1.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M ABC1 PF03109.11 EDN94705.1 - 2.7e-30 104.7 0.0 4.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Thioredoxin PF00085.15 EDN94708.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Reo_sigmaC PF04582.7 EDN94709.1 - 0.48 9.5 18.3 1.2 8.1 2.0 3.4 2 2 2 4 4 4 0 Reovirus sigma C capsid protein FtsJ PF01728.14 EDN94710.1 - 4.1e-41 140.9 0.0 1.8e-40 138.8 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Ribosomal_L18e PF00828.14 EDN94711.1 - 1.9e-24 86.4 0.1 1.9e-24 86.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 EDN94712.1 - 1.5e-74 245.8 4.9 2.3e-24 84.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EDN94713.1 - 4.7e-11 42.1 0.0 6.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN94713.1 - 2.2e-07 30.7 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN94713.1 - 3.4e-07 30.0 0.0 4.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN94713.1 - 0.0022 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DDHD PF02862.12 EDN94714.1 - 5.1e-81 271.7 4.0 1.3e-80 270.4 0.0 2.8 3 0 0 3 3 3 1 DDHD domain DUF2305 PF10230.4 EDN94714.1 - 0.18 11.1 0.1 3 7.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Acetyltransf_6 PF13480.1 EDN94716.1 - 0.026 14.4 0.2 0.43 10.5 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF2304 PF10066.4 EDN94717.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) FCD PF07729.7 EDN94717.1 - 0.066 13.5 0.1 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 FCD domain Ank_2 PF12796.2 EDN94717.1 - 0.093 13.0 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EDN94717.1 - 0.13 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat 4HBT PF03061.17 EDN94718.1 - 7.9e-14 51.5 0.1 1.3e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CH PF00307.26 EDN94720.1 - 7e-64 212.6 0.0 1.3e-17 63.8 0.1 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EDN94720.1 - 8.3e-08 32.2 0.3 1.6e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN94720.1 - 8.1e-06 24.7 1.7 0.12 11.7 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EDN94720.1 - 0.0025 17.5 0.8 0.049 13.5 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EDN94720.1 - 0.41 10.0 3.0 0.38 10.1 0.2 2.5 2 0 0 2 2 2 0 EF hand Hydantoinase_B PF02538.9 EDN94721.1 - 2.6e-200 666.1 0.2 2e-198 659.9 0.2 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EDN94721.1 - 1.7e-92 309.6 1.1 3.8e-92 308.4 0.8 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDN94721.1 - 4.7e-58 195.5 0.9 1.6e-56 190.5 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MIT PF04212.13 EDN94723.1 - 2.4e-12 46.5 1.6 5e-12 45.5 1.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1761 PF08570.5 EDN94724.1 - 6.9e-25 87.4 2.3 7.8e-25 87.3 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CD20 PF04103.10 EDN94724.1 - 0.085 12.7 1.3 0.13 12.2 0.9 1.3 1 0 0 1 1 1 0 CD20-like family His_Phos_1 PF00300.17 EDN94726.1 - 9.9e-14 51.7 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acetyltransf_1 PF00583.19 EDN94727.1 - 1.4e-14 53.8 0.2 6.6e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDN94727.1 - 8e-07 28.7 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EDN94727.1 - 0.00042 20.4 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN94727.1 - 0.0021 18.1 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN94727.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EDN94727.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.1 EDN94727.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 EDN94728.1 - 6.6e-29 100.9 0.0 1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN94728.1 - 6.2e-22 78.5 0.7 3.5e-21 76.0 0.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN94728.1 - 3.1e-14 53.0 0.0 4.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN94728.1 - 3.3e-05 23.4 0.1 0.0003 20.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDN94728.1 - 0.067 13.1 0.1 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding Snf7 PF03357.16 EDN94732.1 - 4.4e-34 117.3 15.9 4.4e-34 117.3 11.0 2.0 2 0 0 2 2 2 1 Snf7 CDI PF02234.14 EDN94732.1 - 0.1 12.4 0.3 0.1 12.4 0.2 2.4 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Fmp27_WPPW PF10359.4 EDN94732.1 - 0.11 10.9 6.4 0.15 10.4 4.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.6 EDN94732.1 - 0.26 10.5 5.6 0.4 9.9 3.9 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.3 EDN94732.1 - 0.9 7.6 7.7 0.84 7.7 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) COMPASS-Shg1 PF05205.7 EDN94732.1 - 6.2 7.1 9.8 2.2 8.6 2.3 2.6 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 BLOC1_2 PF10046.4 EDN94732.1 - 8.9 6.5 12.4 5.4 7.2 4.3 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ten1 PF12658.2 EDN94733.1 - 2.6e-16 59.4 0.1 3e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Fork_head PF00250.13 EDN94738.1 - 2.4e-16 59.5 0.2 4.8e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EDN94738.1 - 3.6e-05 23.7 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain SART-1 PF03343.8 EDN94740.1 - 8.6e-181 602.4 66.1 9.8e-181 602.2 45.8 1.0 1 0 0 1 1 1 1 SART-1 family SIMPL PF04402.9 EDN94740.1 - 0.042 13.7 9.7 0.15 11.8 6.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF541) zf-Di19 PF05605.7 EDN94742.1 - 0.23 11.6 1.6 0.44 10.7 1.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_15 PF00723.16 EDN94743.1 - 3.2e-106 355.5 0.9 4e-106 355.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EDN94743.1 - 5.1e-34 115.7 0.6 1.3e-33 114.4 0.4 1.8 1 0 0 1 1 1 1 Starch binding domain CBM_25 PF03423.8 EDN94743.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PC4 PF02229.11 EDN94744.1 - 1.9e-19 68.5 1.0 1.2e-17 62.9 0.1 2.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Pox_A12 PF04651.8 EDN94744.1 - 0.47 10.5 17.3 0.17 12.0 4.9 2.1 2 0 0 2 2 2 0 Poxvirus A12 protein DUF2890 PF11081.3 EDN94744.1 - 0.75 9.8 21.2 0.048 13.7 9.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ax_dynein_light PF10211.4 EDN94744.1 - 2 8.1 12.9 3.1 7.5 9.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CDC27 PF09507.5 EDN94744.1 - 5.1 6.2 30.9 1.6 7.8 15.5 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 YqfQ PF14181.1 EDN94744.1 - 5.2 7.0 21.0 3.8 7.5 10.1 2.4 2 0 0 2 2 2 0 YqfQ-like protein DUF2457 PF10446.4 EDN94744.1 - 5.8 5.5 30.2 0.094 11.4 14.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PXA PF02194.10 EDN94745.1 - 4.9e-37 127.2 0.1 1.4e-36 125.7 0.0 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EDN94745.1 - 7.5e-21 74.3 2.0 1e-20 73.8 0.0 2.4 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EDN94745.1 - 2.8e-06 27.0 0.6 2e-05 24.3 0.0 2.7 3 1 0 3 3 3 1 PX domain HORMA PF02301.13 EDN94746.1 - 9.6e-46 155.8 0.2 1.4e-45 155.3 0.1 1.2 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 EDN94746.1 - 0.053 13.1 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Alba DUF2660 PF10859.3 EDN94746.1 - 0.5 10.6 3.7 0.28 11.4 0.2 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2660) LepA_C PF06421.7 EDN94747.1 - 4.7e-36 122.9 4.5 7.2e-36 122.3 3.1 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EDN94747.1 - 4.5e-33 114.2 0.0 7.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDN94747.1 - 5.1e-19 67.9 0.0 8.8e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDN94747.1 - 1.8e-06 27.9 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EDN94747.1 - 0.00017 21.0 0.0 0.00085 18.7 0.0 2.0 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 EDN94747.1 - 0.0029 17.3 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EDN94747.1 - 0.043 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SpoIIIAH PF12685.2 EDN94749.1 - 0.0022 17.5 3.2 0.0027 17.2 2.2 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein Apolipoprotein PF01442.13 EDN94749.1 - 0.11 12.0 5.1 0.84 9.1 1.5 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain tRNA-synt_1g PF09334.6 EDN94749.1 - 0.13 10.8 2.6 0.17 10.4 1.8 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DivIVA PF05103.8 EDN94749.1 - 0.28 11.2 7.7 0.047 13.7 2.1 2.0 1 1 1 2 2 2 0 DivIVA protein Borrelia_P83 PF05262.6 EDN94749.1 - 0.5 8.5 10.5 0.55 8.4 7.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.9 EDN94749.1 - 1.4 8.7 11.6 2.1 8.2 8.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 EDN94749.1 - 1.6 5.9 8.5 2 5.6 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Remorin_C PF03763.8 EDN94749.1 - 3.2 7.3 17.0 7.5 6.1 6.9 2.2 1 1 1 2 2 2 0 Remorin, C-terminal region ATP-synt_B PF00430.13 EDN94749.1 - 5.7 6.7 17.4 2.6 7.8 3.1 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HlyD PF00529.15 EDN94749.1 - 7.8 5.7 11.2 0.93 8.7 4.9 1.4 2 0 0 2 2 2 0 HlyD family secretion protein tRNA-synt_1g PF09334.6 EDN94750.1 - 2.4e-140 467.6 0.0 4.3e-140 466.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDN94750.1 - 7.3e-08 30.8 0.1 0.00014 20.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDN94750.1 - 0.0042 16.8 0.3 0.0073 16.0 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SR-25 PF10500.4 EDN94750.1 - 0.24 10.8 9.6 0.37 10.2 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNase_H2-Ydr279 PF09468.5 EDN94750.1 - 1.2 8.2 5.3 2 7.5 3.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 EDN94750.1 - 2.5 7.7 10.0 5.9 6.5 7.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Yae1_N PF09811.4 EDN94751.1 - 2.9e-10 39.4 2.7 2.9e-10 39.4 1.8 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Phage-scaffold PF09306.5 EDN94751.1 - 0.0055 15.9 0.2 0.0069 15.5 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage, scaffolding protein DUF2408 PF10303.4 EDN94752.1 - 6.5e-49 165.4 6.4 4.1e-32 111.0 0.1 5.5 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Laminin_II PF06009.7 EDN94752.1 - 0.018 14.8 3.9 0.13 11.9 0.1 2.9 2 1 1 3 3 3 0 Laminin Domain II Phage_term_smal PF05944.7 EDN94752.1 - 0.021 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Phage small terminase subunit Spc7 PF08317.6 EDN94752.1 - 0.023 13.3 5.3 0.034 12.8 0.2 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EDN94752.1 - 0.25 10.4 1.4 0.25 10.4 0.2 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Nop14 PF04147.7 EDN94752.1 - 0.25 9.2 2.6 0.2 9.5 0.3 1.7 2 0 0 2 2 2 0 Nop14-like family Prefoldin_2 PF01920.15 EDN94752.1 - 0.49 10.1 5.2 3.6 7.4 0.2 3.8 3 1 1 4 4 4 0 Prefoldin subunit DUF1664 PF07889.7 EDN94752.1 - 0.53 10.0 5.6 7.9 6.2 0.3 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.14 EDN94753.1 - 4.1e-26 91.1 9.3 5e-26 90.9 6.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PBP_like PF12727.2 EDN94753.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 PBP superfamily domain YCII PF03795.9 EDN94754.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain OTCace_N PF02729.16 EDN94756.1 - 3.1e-41 140.3 0.0 5e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EDN94756.1 - 7.8e-39 133.0 0.0 1.1e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain AA_permease PF00324.16 EDN94759.1 - 3.4e-121 404.9 44.4 4e-121 404.6 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN94759.1 - 2.5e-38 131.7 46.1 3e-38 131.4 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aconitase PF00330.15 EDN94761.1 - 1.4e-123 412.8 0.0 9.8e-66 222.1 0.0 2.7 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN94761.1 - 6.9e-39 132.9 0.0 1.2e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Cut8_C PF08559.5 EDN94763.1 - 7.6e-53 178.1 0.0 1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EDN94763.1 - 2.5e-17 62.3 1.1 2.5e-17 62.3 0.8 1.8 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 EDN94763.1 - 4.9e-12 45.6 3.5 6.4e-12 45.2 1.8 1.7 2 0 0 2 2 2 1 Cut8 proteasome-binding domain Rad52_Rad22 PF04098.10 EDN94764.1 - 2.3e-62 209.2 0.1 3.8e-62 208.5 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.26 EDN94765.1 - 1.8e-05 24.4 0.0 6.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 EDN94765.1 - 0.0033 17.4 0.8 0.0065 16.5 0.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Med18 PF09637.5 EDN94765.1 - 0.019 14.5 2.3 0.034 13.6 1.6 1.4 1 0 0 1 1 1 0 Med18 protein zf-C2H2 PF00096.21 EDN94765.1 - 0.04 14.2 0.3 0.076 13.3 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Radical_SAM_N PF08497.5 EDN94765.1 - 0.97 8.2 8.6 1.4 7.7 6.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal Ycf1 PF05758.7 EDN94765.1 - 4.6 4.8 11.3 5.3 4.6 7.8 1.3 1 0 0 1 1 1 0 Ycf1 Motile_Sperm PF00635.21 EDN94766.1 - 2.1e-24 85.2 0.1 4e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FA_desaturase PF00487.19 EDN94768.1 - 3.2e-30 105.4 14.0 4.3e-30 105.0 9.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EDN94768.1 - 1.7e-20 71.9 0.2 3.2e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HMG_CoA_synt_C PF08540.5 EDN94769.1 - 3.1e-87 292.6 0.0 3.9e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EDN94769.1 - 1.1e-80 269.2 0.0 2.1e-80 268.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal SRP_SPB PF02978.14 EDN94771.1 - 0.03 14.5 0.3 0.063 13.5 0.2 1.5 1 0 0 1 1 1 0 Signal peptide binding domain Pex19 PF04614.7 EDN94772.1 - 9.3e-75 251.4 14.7 9.3e-75 251.4 10.2 1.8 1 1 1 2 2 2 1 Pex19 protein family Transketolase_N PF00456.16 EDN94772.1 - 0.019 13.7 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain UQ_con PF00179.21 EDN94773.1 - 1.3e-47 160.7 0.0 1.5e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN94773.1 - 0.00031 20.4 0.0 0.0006 19.5 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EDN94773.1 - 0.037 13.9 0.8 0.053 13.4 0.6 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 EDN94774.1 - 9.3e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDN94774.1 - 2.2e-36 124.3 0.0 3.5e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDN94774.1 - 2.6e-29 101.8 0.0 6.8e-29 100.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDN94774.1 - 4.9e-09 35.7 0.0 9e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EDN94774.1 - 0.00029 19.6 0.1 0.0027 16.4 0.0 2.2 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EDN94774.1 - 0.0011 17.9 0.1 0.0051 15.7 0.0 1.9 1 1 0 1 1 1 1 NAD synthase BRX_N PF13713.1 EDN94774.1 - 0.062 12.7 0.0 0.18 11.2 0.0 1.9 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain tRNA_Me_trans PF03054.11 EDN94774.1 - 0.2 10.1 0.0 0.83 8.1 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase QueC PF06508.8 EDN94774.1 - 0.21 10.8 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.17 EDN94776.1 - 2.5e-64 217.2 7.2 2.8e-64 217.0 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 EDN94777.1 - 7e-21 73.7 0.1 1e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 EDN94778.1 - 1.5e-45 155.3 0.1 1.9e-45 154.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2967 PF11179.3 EDN94778.1 - 0.019 14.4 0.7 0.03 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PGA2 PF07543.7 EDN94778.1 - 0.29 10.9 5.6 0.61 9.8 3.8 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_polI_A34 PF08208.6 EDN94778.1 - 3.2 7.3 12.4 6.8 6.3 8.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 APC_CDC26 PF10471.4 EDN94779.1 - 0.055 14.2 0.7 0.091 13.5 0.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF3276 PF11680.3 EDN94779.1 - 0.09 12.5 0.7 0.18 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Diphthamide_syn PF01866.12 EDN94781.1 - 1.1e-113 379.5 0.0 1.3e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DehI PF10778.4 EDN94784.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI FANCAA PF15146.1 EDN94784.1 - 0.031 13.1 0.1 0.031 13.1 0.1 1.0 1 0 0 1 1 1 0 Fanconi anemia-associated Phosphoesterase PF04185.9 EDN94786.1 - 1.9e-28 99.7 0.6 6.4e-28 98.0 0.4 1.7 1 1 0 1 1 1 1 Phosphoesterase family CLN3 PF02487.12 EDN94787.1 - 7.9e-91 304.8 17.9 1.2e-89 300.9 12.4 2.0 1 1 0 1 1 1 1 CLN3 protein Rxt3 PF08642.5 EDN94788.1 - 1.1e-23 83.6 0.0 1.1e-23 83.6 0.0 2.4 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EDN94788.1 - 0.0001 22.2 0.0 0.00068 19.5 0.0 2.2 2 0 0 2 2 2 1 LCCL domain PA_decarbox PF05870.6 EDN94788.1 - 0.13 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) WD40 PF00400.27 EDN94789.1 - 7.5e-06 25.6 8.1 0.0012 18.6 0.1 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PPTA PF01239.17 EDN94790.1 - 8e-25 85.1 11.5 4.4e-06 25.8 0.0 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF4525 PF15027.1 EDN94792.1 - 0.087 12.3 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Aminotran_3 PF00202.16 EDN94800.1 - 9.4e-95 317.3 0.0 1.2e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDN94800.1 - 5e-06 25.7 0.0 1.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1475 PF07343.6 EDN94801.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) adh_short PF00106.20 EDN94802.1 - 1.6e-26 93.2 0.6 2.2e-26 92.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN94802.1 - 1.9e-26 93.3 0.0 2.5e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN94802.1 - 3.8e-13 49.4 0.3 5.8e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1372 PF07116.6 EDN94802.1 - 0.0014 18.5 0.4 0.0036 17.2 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1372) GspH PF12019.3 EDN94802.1 - 0.039 14.0 0.4 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Type II transport protein GspH NLBH PF05211.7 EDN94802.1 - 0.066 12.4 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Methyltransf_23 PF13489.1 EDN94804.1 - 7.1e-17 61.5 0.1 9.6e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN94804.1 - 6.3e-15 55.0 0.0 2.6e-14 53.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN94804.1 - 6.4e-13 49.0 0.0 1.5e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN94804.1 - 3e-12 47.1 0.0 2.7e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN94804.1 - 1.2e-07 32.0 0.0 2.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN94804.1 - 1.9e-07 31.3 0.0 6.2e-07 29.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDN94804.1 - 0.00052 19.1 0.0 0.00099 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EDN94804.1 - 0.0027 16.8 0.0 0.02 14.0 0.0 2.0 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EDN94804.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN94804.1 - 0.0027 17.0 0.0 0.0089 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EDN94804.1 - 0.0057 15.8 0.1 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase DUF938 PF06080.7 EDN94804.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CMAS PF02353.15 EDN94804.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EDN94804.1 - 0.015 14.3 0.0 0.034 13.2 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EDN94804.1 - 0.027 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EDN94804.1 - 0.048 13.6 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EDN94804.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HMGL-like PF00682.14 EDN94806.1 - 6.5e-39 133.9 0.2 3.4e-38 131.6 0.1 1.8 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 EDN94807.1 - 2.8e-60 203.5 0.0 3.8e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN94807.1 - 1.7e-15 57.4 0.2 3.1e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDN94807.1 - 2.7e-12 46.6 0.4 5.7e-12 45.6 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDN94807.1 - 0.0002 21.2 0.2 0.0004 20.2 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain Aldose_epim PF01263.15 EDN94808.1 - 7e-47 159.9 0.0 1.1e-46 159.3 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase PGM_PMM_IV PF00408.15 EDN94813.1 - 0.055 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain HTH_Tnp_Tc5 PF03221.11 EDN94814.1 - 0.00017 21.3 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN94814.1 - 0.064 12.3 0.1 0.21 10.6 0.0 1.7 1 1 1 2 2 2 0 DDE superfamily endonuclease Ferric_reduct PF01794.14 EDN94816.1 - 2.8e-20 72.6 7.9 2.8e-20 72.6 5.5 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDN94816.1 - 4.7e-16 59.0 0.0 6.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN94816.1 - 5.3e-12 45.5 0.0 2e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 FAD-binding domain Sdh_cyt PF01127.17 EDN94816.1 - 0.0011 18.7 3.8 0.0011 18.7 2.6 2.7 3 0 0 3 3 3 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NAD_binding_1 PF00175.16 EDN94816.1 - 0.003 18.0 0.0 0.022 15.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDN94816.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain CitMHS PF03600.11 EDN94816.1 - 0.1 11.1 0.9 0.21 10.1 0.6 1.4 1 0 0 1 1 1 0 Citrate transporter Bromodomain PF00439.20 EDN94818.1 - 1.4e-16 60.1 0.0 2.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3552 PF12072.3 EDN94821.1 - 0.0018 17.5 1.0 0.0023 17.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Allexi_40kDa PF05549.6 EDN94821.1 - 0.019 14.2 0.3 0.026 13.8 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein SlyX PF04102.7 EDN94821.1 - 0.024 14.9 0.2 0.046 14.1 0.1 1.4 1 0 0 1 1 1 0 SlyX Sugarporin_N PF11471.3 EDN94821.1 - 0.08 12.6 2.7 0.14 11.8 1.9 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Atg14 PF10186.4 EDN94821.1 - 0.12 11.3 0.3 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NMT1 PF09084.6 EDN94822.1 - 1.5e-67 227.4 0.0 1.9e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EDN94822.1 - 0.0027 17.1 0.4 0.15 11.4 0.1 3.0 2 1 1 3 3 3 1 NMT1-like family Glyco_hydro_28 PF00295.12 EDN94823.1 - 3.7e-99 331.7 24.5 5.6e-99 331.1 17.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EDN94823.1 - 1.1e-05 25.2 66.2 4.3e-05 23.3 16.2 3.1 1 1 1 3 3 3 2 Right handed beta helix region DUF2470 PF10615.4 EDN94827.1 - 8.6e-19 67.5 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Fun_ATP-synt_8 PF05933.8 EDN94827.1 - 0.53 10.3 2.2 1.2 9.2 0.3 2.2 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DOCK-C2 PF14429.1 EDN94829.1 - 2.8e-29 102.0 0.0 4.7e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EDN94829.1 - 3e-08 33.1 0.0 7.2e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EDN94829.1 - 0.0011 18.2 0.0 0.0038 16.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EDN94829.1 - 0.027 14.0 0.2 0.41 10.2 0.0 2.9 3 0 0 3 3 3 0 Variant SH3 domain An_peroxidase PF03098.10 EDN94830.1 - 3.4e-100 335.9 0.0 3.8e-98 329.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EDN94830.1 - 1.4e-05 23.8 0.0 3.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF3357 PF11837.3 EDN94830.1 - 0.11 12.3 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Steroid_dh PF02544.11 EDN94831.1 - 8.1e-35 119.8 0.5 8.1e-35 119.8 0.4 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EDN94831.1 - 2.6e-05 23.6 0.3 3.8e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EDN94831.1 - 0.00027 20.9 0.2 0.00076 19.5 0.1 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase ubiquitin PF00240.18 EDN94831.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family RA PF00788.18 EDN94831.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Fasciclin PF02469.17 EDN94832.1 - 4.8e-47 159.1 4.9 1.4e-26 92.9 0.4 2.2 2 0 0 2 2 2 2 Fasciclin domain Dynactin PF12455.3 EDN94833.1 - 1.3e-95 319.4 6.0 1.3e-95 319.4 4.2 3.2 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EDN94833.1 - 5.5e-19 67.6 0.5 1e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain p450 PF00067.17 EDN94835.1 - 1.7e-26 92.7 0.0 1.6e-20 73.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 polyprenyl_synt PF00348.12 EDN94836.1 - 5.9e-19 67.9 0.0 4.8e-09 35.4 0.0 2.4 1 1 1 2 2 2 2 Polyprenyl synthetase RabGAP-TBC PF00566.13 EDN94837.1 - 9.5e-48 162.5 0.1 9.5e-48 162.5 0.1 2.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PilJ PF13675.1 EDN94837.1 - 0.0025 18.1 7.1 0.05 13.9 0.5 2.9 1 1 1 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term DUF972 PF06156.8 EDN94837.1 - 0.017 15.4 22.6 0.26 11.6 5.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EDN94837.1 - 0.099 12.2 26.8 1.1 8.7 9.0 2.7 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 EDN94837.1 - 1.2 7.4 3.1 2.1 6.7 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2205 PF10224.4 EDN94837.1 - 3.9 7.1 26.4 3.6 7.2 10.0 3.6 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.10 EDN94837.1 - 4.9 6.7 24.1 3.4 7.2 2.8 3.9 1 1 2 3 3 3 0 Septum formation initiator DUF342 PF03961.8 EDN94837.1 - 5 5.4 18.5 1.2 7.4 10.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3287 PF11690.3 EDN94837.1 - 6.8 6.8 10.2 2.7 8.1 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF913 PF06025.7 EDN94838.1 - 5.3e-114 380.8 0.0 5.3e-114 380.8 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EDN94838.1 - 5.1e-96 321.5 0.0 9.3e-96 320.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EDN94838.1 - 6.3e-76 255.7 1.3 1.2e-75 254.8 0.2 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EDN94838.1 - 6.6e-30 103.2 4.3 6.6e-30 103.2 3.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 EDN94838.1 - 1.9e-05 24.3 0.6 7.4e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain HTH_psq PF05225.11 EDN94839.1 - 9.9e-07 28.2 0.0 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_24 PF13412.1 EDN94839.1 - 0.029 13.7 0.5 0.051 12.9 0.4 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EDN94839.1 - 0.075 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_37 PF13744.1 EDN94839.1 - 0.12 12.2 2.0 0.18 11.5 1.3 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain TPR_MLP1_2 PF07926.7 EDN94840.1 - 0.16 11.7 3.3 0.85 9.3 1.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.6 EDN94841.1 - 8.5e-05 21.9 2.4 8.5e-05 21.9 1.7 1.9 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.7 EDN94841.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.6 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cluap1 PF10234.4 EDN94841.1 - 0.66 9.1 3.9 5.6 6.0 0.6 2.8 2 1 1 3 3 3 0 Clusterin-associated protein-1 Cauli_DNA-bind PF03310.8 EDN94841.1 - 2 8.2 5.8 2.7 7.8 0.5 2.7 2 2 1 3 3 3 0 Caulimovirus DNA-binding protein XendoU PF09412.5 EDN94842.1 - 0.041 12.9 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU Neur_chan_LBD PF02931.18 EDN94843.1 - 0.095 11.8 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain CobT PF06213.7 EDN94845.1 - 0.14 11.3 8.5 0.15 11.1 5.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HEAT PF02985.17 EDN94846.1 - 5.9e-11 41.4 1.7 0.032 14.2 0.0 5.5 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 EDN94846.1 - 7e-06 26.3 0.1 0.26 11.8 0.0 3.1 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 EDN94846.1 - 0.00036 20.7 0.0 0.011 16.0 0.0 2.9 1 1 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.15 EDN94846.1 - 0.01 14.2 0.0 0.022 13.0 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.2 EDN94846.1 - 0.023 14.5 0.0 0.075 12.8 0.0 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDN94846.1 - 0.098 12.0 0.1 0.8 9.0 0.1 2.1 1 1 1 2 2 2 0 CLASP N terminal CoA_trans PF01144.18 EDN94846.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Ydc2-catalyt PF09159.5 EDN94847.1 - 3.9e-86 288.9 2.2 4.5e-86 288.7 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EDN94847.1 - 5.3e-07 29.0 0.1 1.5e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.8 EDN94847.1 - 7.2e-05 22.6 0.1 1.1 9.1 0.0 3.3 4 0 0 4 4 4 2 Poxvirus A22 protein Fis1_TPR_C PF14853.1 EDN94848.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Pyr_redox_2 PF07992.9 EDN94849.1 - 6.6e-31 107.7 6.4 2e-29 102.9 4.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDN94849.1 - 2.7e-25 88.5 0.1 8.3e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 EDN94849.1 - 4.1e-05 23.7 0.4 0.0013 18.8 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN94849.1 - 0.00098 18.1 0.5 0.055 12.3 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EDN94849.1 - 0.002 18.4 3.2 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN94849.1 - 0.018 13.9 1.5 0.018 13.9 1.1 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EDN94849.1 - 0.058 12.4 0.1 0.082 11.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Toxin_62 PF15540.1 EDN94849.1 - 0.08 13.0 0.2 0.56 10.3 0.1 2.2 2 0 0 2 2 2 0 Putative toxin 62 FAD_binding_2 PF00890.19 EDN94849.1 - 0.13 11.0 3.3 1.8 7.3 1.6 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EDN94849.1 - 0.19 10.1 6.0 3.3 6.0 0.0 3.0 2 1 1 3 3 3 0 HI0933-like protein Zn_clus PF00172.13 EDN94850.1 - 0.0021 17.9 34.4 0.0043 16.9 4.8 4.5 3 1 1 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.17 EDN94852.1 - 1.8e-19 70.3 0.0 2.5e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EDN94852.1 - 0.0064 15.8 0.4 0.012 15.0 0.2 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MIP-T3 PF10243.4 EDN94853.1 - 3.3 6.0 32.1 4.7 5.5 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATG_C PF09333.6 EDN94853.1 - 3.4 7.8 10.0 5.3 7.2 1.0 3.3 2 0 0 2 2 2 0 ATG C terminal domain tRNA-synt_1 PF00133.17 EDN94854.1 - 3e-36 124.6 0.0 5.2e-28 97.4 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDN94854.1 - 7.1e-18 64.4 0.0 3.1e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDN94854.1 - 8.4e-11 41.8 0.2 8.4e-11 41.8 0.2 2.5 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDN94854.1 - 4.3e-07 29.3 0.0 8.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.15 EDN94856.1 - 3.8e-43 146.6 0.1 1.1e-42 145.1 0.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EDN94857.1 - 2.1e-35 120.7 0.0 2.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DUF4110 PF13422.1 EDN94857.1 - 0.019 14.7 0.2 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Sds3 PF08598.6 EDN94857.1 - 0.031 13.8 0.1 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Sds3-like Adeno_terminal PF02459.10 EDN94857.1 - 0.085 11.0 0.5 0.11 10.6 0.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein zf-CSL PF05207.8 EDN94858.1 - 1.7e-23 81.8 0.4 2.1e-23 81.5 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EDN94858.1 - 0.15 12.0 1.2 0.29 11.1 0.8 1.5 1 1 0 1 1 1 0 Zinc ribbon domain SspH PF08141.7 EDN94863.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Ribosomal_S8e PF01201.17 EDN94864.1 - 1.5e-45 154.5 1.5 1.7e-45 154.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EDN94864.1 - 1.1 9.5 5.6 0.42 10.9 1.2 2.3 2 1 0 2 2 2 0 Small acidic protein family GCN5L1 PF06320.8 EDN94865.1 - 1e-05 25.3 1.8 0.00011 22.0 1.3 2.1 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF2884 PF11101.3 EDN94865.1 - 0.0029 17.0 0.2 0.0049 16.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Tektin PF03148.9 EDN94865.1 - 0.0053 15.3 1.3 0.0077 14.8 0.9 1.2 1 0 0 1 1 1 1 Tektin family CENP-F_leu_zip PF10473.4 EDN94865.1 - 0.0065 16.3 2.3 0.0065 16.3 1.6 1.6 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.3 EDN94865.1 - 0.0084 16.1 0.3 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 AT-hook-containing transcription factor Exonuc_VII_L PF02601.10 EDN94865.1 - 0.01 15.0 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.3 EDN94865.1 - 0.011 14.9 3.0 0.016 14.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Not3 PF04065.10 EDN94865.1 - 0.012 14.8 1.2 0.021 14.1 0.8 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Jnk-SapK_ap_N PF09744.4 EDN94865.1 - 0.041 13.8 1.2 0.069 13.1 0.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF677 PF05055.7 EDN94865.1 - 0.069 11.8 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) APG6 PF04111.7 EDN94865.1 - 0.13 11.3 2.1 0.22 10.5 1.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EDN94865.1 - 0.14 12.1 5.2 0.32 11.0 3.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EDN94865.1 - 0.4 10.2 1.7 0.78 9.2 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Neugrin PF06413.6 EDN94865.1 - 0.64 9.8 8.2 0.038 13.8 1.5 1.9 2 0 0 2 2 2 0 Neugrin TMF_TATA_bd PF12325.3 EDN94865.1 - 0.89 9.3 5.5 0.1 12.3 0.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RAP1 PF07218.6 EDN94865.1 - 9.2 4.2 12.6 0.038 12.1 1.0 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF3237 PF11578.3 EDN94866.1 - 3.2e-54 182.3 0.0 3.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SP2 PF03014.9 EDN94868.1 - 0.051 11.4 0.0 0.061 11.1 0.0 1.0 1 0 0 1 1 1 0 Structural protein 2 6PF2K PF01591.13 EDN94870.1 - 1.1e-81 273.1 0.7 1.4e-81 272.7 0.5 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN94870.1 - 1.2e-31 109.9 0.0 2.4e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDN94870.1 - 1.3e-06 28.3 0.1 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDN94870.1 - 1.9e-05 24.0 0.1 3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EDN94870.1 - 0.0014 19.4 0.2 0.014 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF4248 PF14053.1 EDN94870.1 - 0.015 14.8 0.3 1.9 8.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) Zeta_toxin PF06414.7 EDN94870.1 - 0.029 13.4 0.0 0.73 8.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_membrane_2 PF06472.10 EDN94872.1 - 3.7e-107 357.6 1.2 5.8e-107 357.0 0.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDN94872.1 - 2.3e-17 63.5 0.0 4.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN94872.1 - 0.00084 19.3 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN94872.1 - 0.012 15.6 0.2 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EDN94872.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 EDN94872.1 - 0.034 13.1 0.1 0.89 8.5 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 EDN94872.1 - 0.042 14.1 0.4 0.094 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EDN94872.1 - 0.055 12.6 0.2 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ank_2 PF12796.2 EDN94874.1 - 4.6e-21 74.9 0.7 2.5e-08 34.1 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN94874.1 - 6.4e-16 57.2 0.0 0.11 12.3 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EDN94874.1 - 4.1e-13 49.4 0.0 2.3e-05 24.7 0.0 4.5 2 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 EDN94874.1 - 6.4e-10 38.9 0.1 3.2e-09 36.6 0.0 2.2 3 0 0 3 3 3 1 NACHT domain Ank_3 PF13606.1 EDN94874.1 - 2.7e-08 33.2 0.0 3.7 8.0 0.0 5.6 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.1 EDN94874.1 - 1.5e-07 31.4 0.0 0.27 11.5 0.0 4.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EDN94874.1 - 3.5e-07 30.3 0.1 3.7e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN94874.1 - 6.2e-06 26.3 0.0 2.3e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN94874.1 - 0.0024 18.0 0.4 0.025 14.7 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EDN94874.1 - 0.0025 16.8 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EDN94874.1 - 0.0081 15.0 0.0 0.02 13.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EDN94874.1 - 0.018 15.8 0.8 0.31 11.8 0.1 3.2 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDN94874.1 - 0.059 12.4 0.0 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EDN94874.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EDN94874.1 - 0.077 12.7 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EDN94874.1 - 0.11 12.8 0.5 38 4.6 0.0 3.5 2 1 0 2 2 2 0 AAA domain Ctf8 PF09696.5 EDN94877.1 - 4.6e-39 132.9 0.0 5.5e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.14 EDN94878.1 - 2.7e-62 208.0 0.3 2.7e-62 208.0 0.2 1.7 2 1 0 2 2 2 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 EDN94879.1 - 4.1e-43 145.7 0.3 4.1e-42 142.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDN94879.1 - 1.1e-41 142.6 2.2 7.9e-35 120.2 1.0 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDN94879.1 - 1.6e-11 44.0 1.5 9.7e-11 41.4 0.7 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDN94879.1 - 0.0013 18.0 0.3 0.002 17.3 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EDN94879.1 - 0.042 13.3 0.1 0.21 11.0 0.1 2.1 1 1 0 1 1 1 0 DUF218 domain Chlorosome_CsmC PF11098.3 EDN94879.1 - 0.15 11.7 1.8 0.31 10.7 1.2 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C DEAD PF00270.24 EDN94882.1 - 2.5e-18 66.1 0.0 1.6e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN94882.1 - 3.7e-08 33.1 0.0 1.7e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN94882.1 - 0.029 13.1 0.2 0.054 12.2 0.1 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain SOG2 PF10428.4 EDN94883.1 - 7.4e-115 384.1 0.0 1.7e-114 382.9 0.0 1.6 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EDN94883.1 - 1e-17 63.3 6.1 8.8e-09 34.8 2.1 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN94883.1 - 5.1e-16 58.1 3.6 4.7e-10 39.0 1.1 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EDN94883.1 - 5.5e-10 37.8 4.4 0.15 12.2 0.1 6.1 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EDN94883.1 - 5.7e-08 31.7 4.1 2 8.9 0.0 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EDN94883.1 - 1.7 8.9 11.1 28 5.1 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Tcp11 PF05794.8 EDN94885.1 - 1.1e-34 119.9 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 WD40 PF00400.27 EDN94887.1 - 2.1e-46 154.1 16.6 6.7e-11 41.6 0.5 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDN94887.1 - 0.07 12.6 0.0 2.7 7.5 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PNGaseA PF12222.3 EDN94889.1 - 1.5e-148 495.2 8.4 2.1e-148 494.7 5.8 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ribosom_S12_S23 PF00164.20 EDN94894.1 - 3.5e-41 139.4 0.5 4.2e-41 139.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ADH_zinc_N_2 PF13602.1 EDN94895.1 - 0.2 12.5 1.4 0.38 11.6 0.7 1.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase TFIID-18kDa PF02269.11 EDN94897.1 - 1.1e-18 66.8 0.1 1.4e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EDN94897.1 - 0.0013 18.9 0.1 0.0021 18.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EDN94897.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EDN94897.1 - 0.0026 17.7 0.2 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN94897.1 - 0.0043 17.1 0.1 0.0066 16.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cullin_binding PF03556.10 EDN94898.1 - 0.042 13.9 0.1 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Cullin binding SUR7 PF06687.7 EDN94899.1 - 2.5e-41 141.5 20.3 3e-41 141.3 14.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EDN94899.1 - 0.069 13.0 11.1 0.21 11.4 7.0 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Shisa PF13908.1 EDN94899.1 - 3 7.9 4.5 3.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Amidohydro_2 PF04909.9 EDN94900.1 - 6.9e-09 35.6 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EDN94900.1 - 0.0003 20.9 0.0 0.0007 19.7 0.0 1.5 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EDN94900.1 - 0.016 14.8 0.3 0.079 12.5 0.2 1.9 1 1 0 1 1 1 0 Amidohydrolase family SNF2_N PF00176.18 EDN94901.1 - 6.2e-83 278.0 0.2 1.1e-82 277.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EDN94901.1 - 9.1e-46 154.4 1.3 3.2e-45 152.6 0.9 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EDN94901.1 - 1.4e-36 125.3 2.5 1.4e-36 125.3 1.7 4.1 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 EDN94901.1 - 1.2e-14 53.9 0.0 3.7e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN94901.1 - 3.9e-09 36.5 0.0 2.9e-08 33.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDN94901.1 - 1.3e-05 24.7 0.0 3.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EDN94901.1 - 2.7e-05 23.1 0.0 7e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 EDN94901.1 - 0.032 13.6 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EDN94901.1 - 0.05 13.5 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EDN94901.1 - 2.9 6.7 14.0 0.2 10.5 0.5 3.7 4 0 0 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4588 PF15251.1 EDN94902.1 - 0.093 12.6 9.5 0.32 10.9 6.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF2204 PF09970.4 EDN94906.1 - 0.055 12.9 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) RNase_H PF00075.19 EDN94907.1 - 9.3e-15 55.1 0.1 1.9e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 RNase H GnsAB PF08178.6 EDN94907.1 - 0.03 13.9 0.1 0.094 12.3 0.0 1.8 1 0 0 1 1 1 0 GnsA/GnsB family DUF3602 PF12223.3 EDN94908.1 - 3.2e-20 72.2 16.3 7.8e-16 58.2 1.1 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Metallophos_C PF14008.1 EDN94908.1 - 0.75 9.9 2.9 6.3 6.9 0.1 2.9 3 0 0 3 3 3 0 Iron/zinc purple acid phosphatase-like protein C DUF3270 PF11674.3 EDN94910.1 - 0.054 13.5 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) FHA PF00498.21 EDN94911.1 - 1.1e-14 54.2 0.0 3.3e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain IFRD PF05004.8 EDN94912.1 - 1.4e-35 122.9 1.2 2.4e-35 122.1 0.8 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EDN94912.1 - 0.00058 20.2 0.6 3.4 8.2 0.1 3.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EDN94912.1 - 0.00067 19.8 0.3 0.034 14.4 0.3 2.6 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 EDN94912.1 - 0.0018 18.1 0.2 2.9 8.2 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat Unstab_antitox PF09720.5 EDN94912.1 - 0.014 15.0 0.6 0.072 12.7 0.4 2.3 1 0 0 1 1 1 0 Putative addiction module component V_ATPase_I PF01496.14 EDN94912.1 - 0.048 11.5 0.1 0.2 9.4 0.0 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Corona_nucleoca PF00937.13 EDN94912.1 - 0.74 8.6 5.0 1.4 7.7 3.5 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Oxysterol_BP PF01237.13 EDN94913.1 - 9.4e-114 379.5 0.0 3.9e-113 377.5 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EDN94913.1 - 2.1e-38 130.2 1.6 3e-38 129.7 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EDN94913.1 - 0.00012 22.2 0.5 0.0008 19.5 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EDN94913.1 - 0.018 15.2 5.0 0.3 11.3 1.4 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain SH2_2 PF14633.1 EDN94915.1 - 2e-83 278.8 0.1 5.3e-83 277.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EDN94915.1 - 1.2e-36 125.2 5.0 1.2e-36 125.2 3.4 3.8 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 EDN94915.1 - 1.1e-32 112.6 0.0 3e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EDN94915.1 - 3.2e-31 107.5 0.0 1.4e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EDN94915.1 - 1.3e-23 82.9 27.5 1.3e-23 82.9 19.1 5.9 4 1 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EDN94915.1 - 1.9e-18 66.5 4.5 2.2e-17 63.1 3.1 2.7 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EDN94915.1 - 0.00014 21.5 0.0 0.00048 19.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EDN94915.1 - 0.0029 17.6 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 S1 RNA binding domain HHH_3 PF12836.2 EDN94915.1 - 0.072 13.0 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pkinase PF00069.20 EDN94917.1 - 8.6e-60 202.0 0.0 1.2e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN94917.1 - 8.7e-41 139.7 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN94917.1 - 3.2e-06 26.3 0.0 7.5e-06 25.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Totivirus_coat PF05518.6 EDN94917.1 - 2.9 5.5 8.4 4.5 4.9 5.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein Hydrolase_like PF13242.1 EDN94920.1 - 1.8e-10 40.4 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EDN94920.1 - 6.8e-10 39.4 0.0 7.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN94920.1 - 2.8e-08 34.4 0.0 3.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDN94920.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Cupin_1 PF00190.17 EDN94921.1 - 5e-27 94.1 0.0 2.9e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EDN94921.1 - 3.2e-26 90.6 0.0 3.8e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EDN94921.1 - 5.1e-10 38.6 0.0 0.00016 21.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EDN94921.1 - 2.8e-06 27.0 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EDN94921.1 - 8.6e-05 22.2 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.7 EDN94921.1 - 0.00065 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.3 EDN94921.1 - 0.0016 18.4 0.0 0.056 13.4 0.0 2.4 2 0 0 2 2 2 1 Mif2/CENP-C like FdtA PF05523.6 EDN94921.1 - 0.0034 16.8 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal Cupin_6 PF12852.2 EDN94921.1 - 0.014 15.0 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 Cupin Auxin_BP PF02041.11 EDN94921.1 - 0.032 13.6 0.0 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein ARD PF03079.9 EDN94921.1 - 0.039 13.8 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family Glyco_tran_28_C PF04101.11 EDN94922.1 - 1.3e-20 73.7 0.0 1.7e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EDN94922.1 - 0.00029 20.1 0.0 0.00045 19.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 EDN94922.1 - 0.096 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.4 EDN94923.1 - 1.6e-24 86.3 0.0 3.7e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF1743 PF08489.6 EDN94923.1 - 0.021 14.5 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) Aldedh PF00171.17 EDN94924.1 - 5.8e-77 258.9 0.0 7e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sec6 PF06046.8 EDN94924.1 - 0.0042 15.2 0.2 0.0057 14.7 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 COMPASS-Shg1 PF05205.7 EDN94926.1 - 0.024 14.9 0.2 0.028 14.7 0.1 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3897 PF13036.1 EDN94926.1 - 0.098 12.2 0.2 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) DHHW PF14286.1 EDN94926.1 - 0.1 11.8 1.4 0.11 11.8 0.9 1.0 1 0 0 1 1 1 0 DHHW protein ADH_N PF08240.7 EDN94928.1 - 4.3e-19 68.2 2.8 8.5e-19 67.3 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN94928.1 - 2.8e-15 56.0 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EDN94928.1 - 3.2e-05 23.5 0.2 6.2e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN94928.1 - 5.9e-05 22.2 0.0 9.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EDN94928.1 - 0.0018 19.1 0.0 0.0051 17.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EDN94928.1 - 0.0019 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EDN94928.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EDN94928.1 - 0.012 15.2 0.1 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EDN94928.1 - 0.063 12.7 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EDN94928.1 - 0.083 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.17 EDN94928.1 - 0.12 12.8 0.4 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ECR1_N PF14382.1 EDN94929.1 - 6.1e-10 38.2 0.1 1.1e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EDN94929.1 - 0.0013 18.6 0.0 0.019 14.9 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EDN94929.1 - 0.021 14.8 4.2 0.085 12.9 0.0 3.4 4 0 0 4 4 4 0 S1 RNA binding domain PMP1_2 PF08114.6 EDN94931.1 - 0.0091 15.4 4.8 0.014 14.8 2.1 2.2 2 0 0 2 2 2 1 ATPase proteolipid family DUF2304 PF10066.4 EDN94931.1 - 0.069 13.0 0.4 0.097 12.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF4149 PF13664.1 EDN94931.1 - 0.072 13.1 1.5 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF2301 PF10063.4 EDN94931.1 - 0.26 11.4 2.2 0.39 10.9 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) 7tm_2 PF00002.19 EDN94931.1 - 0.36 9.8 5.4 0.74 8.8 3.7 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) ABC2_membrane_3 PF12698.2 EDN94931.1 - 1.3 7.9 5.9 1.6 7.6 4.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4536 PF15055.1 EDN94932.1 - 0.00037 20.4 2.8 0.0015 18.5 1.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 EDN94933.1 - 3.2e-60 203.4 0.0 4.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDN94933.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.4 2 0 0 2 2 2 1 Clathrin adaptor complex small chain SSP160 PF06933.6 EDN94934.1 - 1 7.2 1.2 1.7 6.5 0.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ubiquitin PF00240.18 EDN94936.1 - 0.0085 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PSK_trans_fac PF07704.6 EDN94938.1 - 3.4 8.4 7.9 8.9 7.0 0.2 3.5 2 2 2 4 4 4 0 Rv0623-like transcription factor Ribosomal_L17 PF01196.14 EDN94939.1 - 2.2e-31 108.2 0.0 3.7e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 DUF1253 PF06862.7 EDN94940.1 - 3.2e-172 572.9 0.2 4.5e-172 572.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF3347 PF11827.3 EDN94940.1 - 1.4 8.9 12.4 1.3 9.0 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) JAB PF01398.16 EDN94941.1 - 7.6e-16 57.8 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDN94941.1 - 5.6e-15 55.4 0.1 8.8e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3113 PF11310.3 EDN94941.1 - 0.063 12.9 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) SUZ PF12752.2 EDN94942.1 - 2.5e-16 59.9 2.2 2.5e-16 59.9 1.5 2.3 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EDN94942.1 - 1.8e-09 37.1 0.0 3.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EDN94943.1 - 2.2e-10 40.0 0.7 3.3e-10 39.5 0.5 1.2 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.7 EDN94944.1 - 5.6e-45 152.9 4.5 5.6e-45 152.9 3.1 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF3585 PF12130.3 EDN94944.1 - 1.3 8.8 14.0 4.8 7.0 9.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3585) PPR_2 PF13041.1 EDN94945.1 - 3.3e-23 81.4 1.8 1.9e-10 40.5 0.2 4.9 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EDN94945.1 - 9.8e-13 47.2 0.2 0.00035 20.6 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EDN94945.1 - 5.1e-12 44.9 0.0 0.0028 17.5 0.0 4.7 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EDN94945.1 - 1.4e-10 40.5 0.0 0.032 13.7 0.0 5.3 5 0 0 5 5 5 3 PPR repeat TPR_14 PF13428.1 EDN94945.1 - 0.067 13.8 0.7 9.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 EDN94946.1 - 9e-23 81.1 0.0 1.1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4164 PF13747.1 EDN94946.1 - 0.088 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Methyltransf_16 PF10294.4 EDN94947.1 - 4.2e-24 84.9 0.0 5.3e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDN94947.1 - 0.0062 15.9 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EDN94947.1 - 0.036 14.6 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SMN PF06003.7 EDN94950.1 - 6.5e-06 25.4 5.4 0.0001 21.5 1.3 2.4 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) Nsp1_C PF05064.8 EDN94950.1 - 0.062 12.9 1.2 0.13 11.9 0.5 1.8 2 1 0 2 2 2 0 Nsp1-like C-terminal region Turandot PF07240.6 EDN94950.1 - 0.072 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Cu_bind_like PF02298.12 EDN94951.1 - 0.002 17.9 0.1 0.0076 16.0 0.1 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain DUF11 PF01345.13 EDN94951.1 - 2.9 8.0 11.3 0.43 10.6 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function DUF11 DUF566 PF04484.7 EDN94952.1 - 1.9 7.9 9.3 2.1 7.7 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SWI-SNF_Ssr4 PF08549.5 EDN94952.1 - 4.4 5.4 5.8 5.1 5.2 4.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.4 EDN94952.1 - 6.6 4.8 12.3 7.4 4.7 8.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 EDN94952.1 - 6.6 5.3 6.2 6.9 5.3 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) WD40 PF00400.27 EDN94953.1 - 5e-31 105.4 17.1 1.4e-11 43.7 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 EDN94953.1 - 0.0012 17.9 0.3 0.62 9.1 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Ribosomal_L32p PF01783.18 EDN94954.1 - 1.6e-14 53.8 1.0 2.2e-14 53.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 EDN94954.1 - 0.41 10.2 2.4 13 5.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Septin PF00735.13 EDN94955.1 - 1.9e-111 371.6 0.7 2.3e-111 371.3 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EDN94955.1 - 4.2e-07 29.9 0.0 7.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EDN94955.1 - 2e-06 27.0 0.0 3.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EDN94955.1 - 2.1e-05 23.7 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDN94955.1 - 0.00033 20.1 0.9 0.0037 16.7 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDN94955.1 - 0.00036 20.4 0.7 0.96 9.2 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_23 PF13476.1 EDN94955.1 - 0.0014 19.0 0.2 0.0019 18.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDN94955.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EDN94955.1 - 0.0073 16.6 0.3 0.012 15.9 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EDN94955.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EDN94955.1 - 0.025 13.7 0.1 0.088 11.9 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 EDN94955.1 - 0.026 13.4 0.0 0.054 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 EDN94955.1 - 0.03 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EDN94955.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EDN94955.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 EDN94955.1 - 0.068 12.5 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 Ras family Guanylate_kin PF00625.16 EDN94956.1 - 2.2e-52 177.1 0.0 2.7e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EDN94956.1 - 8.7e-05 22.8 0.7 0.0039 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN94956.1 - 0.00023 21.9 0.0 0.00052 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN94956.1 - 0.00038 20.3 0.0 0.0042 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN94956.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN94956.1 - 0.0016 18.5 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN94956.1 - 0.031 14.2 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF1895 PF08988.5 EDN94956.1 - 0.092 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) MMR_HSR1 PF01926.18 EDN94956.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase 4F5 PF04419.9 EDN94957.1 - 2.1e-07 31.5 16.0 2.1e-07 31.5 11.1 2.3 2 0 0 2 2 2 1 4F5 protein family SPOR PF05036.8 EDN94957.1 - 0.74 10.0 5.4 0.9 9.7 3.8 1.1 1 0 0 1 1 1 0 Sporulation related domain Selenoprotein_S PF06936.6 EDN94957.1 - 3.3 7.2 8.4 3.5 7.1 5.8 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3481 PF11980.3 EDN94958.1 - 0.18 11.6 0.3 0.53 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) WD40 PF00400.27 EDN94959.1 - 8.6e-50 164.9 19.3 1.5e-11 43.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDN94959.1 - 2.4e-05 22.7 4.2 0.37 8.8 0.0 4.7 2 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 EDN94959.1 - 0.00076 17.8 0.0 0.0015 16.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 EDN94959.1 - 0.0039 16.0 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Hira PF07569.6 EDN94959.1 - 0.039 13.1 0.3 12 5.0 0.0 2.9 1 1 2 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EDN94959.1 - 0.049 12.3 0.2 2 7.0 0.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Fer2_4 PF13510.1 EDN94961.1 - 0.024 14.4 0.5 2.7 7.8 0.1 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF2892 PF11127.3 EDN94961.1 - 9.3 6.1 7.4 0.56 10.0 1.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) Chorismate_bind PF00425.13 EDN94964.1 - 0.094 12.0 0.1 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 chorismate binding enzyme Glyco_hydro_35 PF01301.14 EDN94967.1 - 4.6e-77 259.4 4.6 7.2e-77 258.8 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EDN94967.1 - 2.1e-52 177.1 6.2 4.8e-52 175.9 4.3 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EDN94967.1 - 6.1e-47 158.4 10.3 9e-24 83.8 1.0 3.6 3 1 1 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EDN94967.1 - 5e-25 86.7 0.3 2.9e-24 84.2 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EDN94967.1 - 1.2e-06 27.9 0.0 4.7e-05 22.6 0.1 2.6 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.13 EDN94967.1 - 3e-05 23.3 0.1 6.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF605 PF04652.11 EDN94968.1 - 2.8 7.2 19.7 3.4 6.9 13.6 1.2 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EDN94968.1 - 4.6 5.5 19.8 5.7 5.2 13.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_12 PF01670.11 EDN94970.1 - 0.019 14.7 1.7 0.27 11.0 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 EDN94972.1 - 5.6e-37 127.7 0.0 8.6e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDN94972.1 - 4.9e-24 85.1 0.2 4.9e-24 85.1 0.1 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EDN94972.1 - 2.7e-12 46.3 0.0 4.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN94972.1 - 1.6e-10 40.9 0.0 4.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 EDN94972.1 - 6.7e-10 37.9 8.2 1.9e-08 33.1 2.8 2.9 1 1 2 3 3 3 2 Cellulose synthase Chitin_synth_2 PF03142.10 EDN94972.1 - 0.00019 19.9 0.8 0.012 14.0 0.1 3.0 3 0 0 3 3 3 1 Chitin synthase AA_permease PF00324.16 EDN94974.1 - 7.3e-62 209.2 28.9 2.7e-61 207.3 20.1 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN94974.1 - 1.5e-23 83.0 26.2 2.7e-23 82.2 18.2 1.4 1 1 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EDN94974.1 - 0.81 8.2 4.4 1.2 7.6 0.4 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 EDN94981.1 - 5.6e-06 25.2 0.1 5.6e-06 25.2 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN94981.1 - 0.00029 19.6 0.0 0.00031 19.5 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EDN94981.1 - 0.0016 16.5 0.3 0.002 16.2 0.2 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EDN94982.1 - 4.6e-24 84.8 4.8 5.2e-24 84.6 3.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DNA_pol_phi PF04931.8 EDN94984.1 - 3.7 5.1 8.2 4 5.0 5.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DGCR6 PF07324.6 EDN94985.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1610 PF07754.6 EDN94986.1 - 0.019 15.0 0.7 0.041 14.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) CHORD PF04968.7 EDN94986.1 - 0.98 9.7 11.7 0.07 13.3 1.6 2.7 1 1 0 2 2 2 0 CHORD BTK PF00779.14 EDN94987.1 - 0.017 14.6 1.0 0.028 14.0 0.7 1.4 1 0 0 1 1 1 0 BTK motif TFIIF_alpha PF05793.7 EDN94987.1 - 0.45 8.8 13.2 0.52 8.6 9.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) P5CR_dimer PF14748.1 EDN94989.1 - 3.3e-24 84.9 0.2 1e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDN94989.1 - 1.2e-12 48.0 1.2 2.6e-12 47.0 0.3 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EDN94989.1 - 0.026 14.3 0.3 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EDN94989.1 - 0.081 12.5 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HET PF06985.6 EDN94990.1 - 3.2e-06 27.3 0.1 0.0029 17.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.9 EDN94992.1 - 8.3e-40 137.3 16.0 1.1e-39 136.9 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MutL_C PF08676.6 EDN94995.1 - 3e-07 30.1 0.0 2e-06 27.4 0.0 2.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EDN94997.1 - 3.3e-12 46.2 0.0 3.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN94997.1 - 0.0001 21.9 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COesterase PF00135.23 EDN95000.1 - 2.8e-84 283.7 0.7 3.5e-84 283.4 0.5 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN95000.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN95000.1 - 0.0048 16.1 0.1 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN95000.1 - 0.02 14.6 0.1 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EDN95001.1 - 5.4e-10 39.0 8.3 1.1e-09 38.0 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN95001.1 - 2.5e-05 23.2 0.6 3.8e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RVT_1 PF00078.22 EDN95004.1 - 5.4e-35 120.6 0.0 9.9e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN95004.1 - 1e-10 42.0 0.0 2.7e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 RNase H PG_binding_3 PF09374.5 EDN95004.1 - 0.16 11.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Predicted Peptidoglycan domain NAD_binding_1 PF00175.16 EDN95005.1 - 1.4e-09 38.4 0.0 2.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDN95005.1 - 2.2e-09 37.3 0.0 3.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EDN95005.1 - 4.3e-08 33.4 0.3 1.4e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 EDN95005.1 - 9.9e-07 28.7 0.0 0.00031 20.6 0.0 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Protoglobin PF11563.3 EDN95005.1 - 0.0016 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Protoglobin NMO PF03060.10 EDN95006.1 - 1.3e-41 142.8 2.9 5.5e-41 140.8 2.0 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EDN95006.1 - 5.8e-10 38.5 1.0 7.5e-10 38.1 0.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EDN95006.1 - 0.00016 20.7 0.5 0.023 13.5 0.4 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EDN95006.1 - 0.00017 20.6 0.2 0.00028 19.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Alpha-amylase PF00128.19 EDN95007.1 - 1.1e-53 182.7 1.8 1.5e-53 182.2 1.3 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN95007.1 - 1.5e-21 76.2 0.7 6.4e-21 74.2 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EDN95007.1 - 0.086 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 DUF4611 PF15387.1 EDN95010.1 - 1.4 9.1 7.4 0.13 12.4 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PP2C PF00481.16 EDN95011.1 - 5.2e-42 144.0 0.0 9.8e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDN95011.1 - 0.00054 19.7 0.3 0.27 10.9 0.0 3.2 4 0 0 4 4 4 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EDN95011.1 - 0.0036 16.7 0.3 0.07 12.5 0.1 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C Tcf25 PF04910.9 EDN95012.1 - 1.4e-85 287.4 0.4 2.2e-85 286.8 0.3 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PsiA PF06952.6 EDN95012.1 - 0.68 8.9 5.6 0.19 10.7 0.1 2.5 3 0 0 3 3 3 0 PsiA protein HMA PF00403.21 EDN95013.1 - 1.5e-14 53.9 0.4 3.5e-14 52.6 0.1 1.7 1 1 1 2 2 2 1 Heavy-metal-associated domain Peptidase_M4 PF01447.13 EDN95014.1 - 2.1e-16 60.3 1.0 2.9e-16 59.9 0.7 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Thiolase_C PF02803.13 EDN95015.1 - 7.4e-11 41.5 2.1 2e-10 40.1 0.3 2.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EDN95015.1 - 1.4e-07 31.0 0.0 1.2e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EDN95015.1 - 9.7e-06 24.7 0.1 8e-05 21.7 0.0 2.4 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EDN95015.1 - 0.0013 18.3 0.5 0.0029 17.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDN95015.1 - 0.0074 16.1 0.2 0.79 9.5 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 EDN95015.1 - 0.023 13.1 0.3 0.06 11.7 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) DFP PF04127.10 EDN95015.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HsbA PF12296.3 EDN95017.1 - 8e-24 83.8 1.8 1.2e-23 83.2 1.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A RNA_replicase_B PF03431.8 EDN95017.1 - 0.11 10.6 0.2 0.15 10.2 0.2 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain MFS_1 PF07690.11 EDN95018.1 - 8.1e-14 51.0 32.9 1.7e-13 50.0 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDN95018.1 - 2.8e-11 43.1 4.5 2.8e-11 43.1 3.1 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DAO PF01266.19 EDN95020.1 - 1.5e-51 175.4 0.0 2e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN95020.1 - 1.6e-10 40.4 1.0 5.6e-10 38.6 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDN95020.1 - 1.6e-06 27.4 0.1 4.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN95020.1 - 4.3e-06 26.7 0.1 0.00067 19.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN95020.1 - 0.0021 18.0 0.2 0.0069 16.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EDN95020.1 - 0.0036 16.2 0.3 0.14 10.9 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDN95020.1 - 0.0039 16.8 0.2 0.007 16.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EDN95020.1 - 0.01 14.8 0.0 0.2 10.5 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EDN95020.1 - 0.011 16.1 0.2 0.047 14.1 0.2 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN95020.1 - 0.012 14.1 0.2 0.021 13.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EDN95020.1 - 0.032 13.3 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EDN95020.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EDN95020.1 - 0.19 9.9 0.2 1.5 7.0 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Sugar_tr PF00083.19 EDN95021.1 - 1.7e-75 254.3 19.1 2e-75 254.1 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN95021.1 - 2e-16 59.6 13.1 1.3e-11 43.8 0.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 EDN95021.1 - 0.0069 15.6 5.4 0.0069 15.6 3.7 1.8 2 0 0 2 2 2 1 Tetraspanin family DUF676 PF05057.9 EDN95022.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3638 PF12340.3 EDN95022.1 - 0.0058 15.6 0.0 0.008 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DnaJ PF00226.26 EDN95023.1 - 2.8e-10 39.7 0.2 9.8e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Aldo_ket_red PF00248.16 EDN95025.1 - 4.1e-79 265.3 0.0 5.1e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.14 EDN95025.1 - 0.081 12.5 0.1 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 HMGL-like DUF3328 PF11807.3 EDN95031.1 - 2.1e-29 102.7 0.8 2.6e-29 102.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Rad54_N PF08658.5 EDN95032.1 - 0.078 12.7 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Rad54 N terminal UPF0029 PF01205.14 EDN95033.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Rio2_N PF09202.6 EDN95035.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Rio2, N-terminal Rogdi_lz PF10259.4 EDN95036.1 - 0.064 12.3 0.1 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RasGEF PF00617.14 EDN95043.1 - 3e-58 196.6 0.1 7.2e-58 195.4 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDN95043.1 - 4.3e-18 65.3 0.0 2.8e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EDN95043.1 - 9.2e-06 25.1 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN95043.1 - 0.00017 20.8 0.0 0.00035 19.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Meth_synt_2 PF01717.13 EDN95044.1 - 3.6e-146 486.2 0.0 2.2e-139 463.9 0.0 2.8 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDN95044.1 - 5.6e-123 410.1 0.0 8.9e-111 370.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EDN95044.1 - 0.0011 17.9 0.1 1.4 7.7 0.0 2.8 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 EDN95044.1 - 0.088 12.3 2.9 0.33 10.4 0.1 2.8 2 0 0 2 2 2 0 Short C-terminal domain Bac_small_YrzI PF09501.5 EDN95044.1 - 0.096 12.6 1.7 1.2 9.1 1.7 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) AA_permease_2 PF13520.1 EDN95045.1 - 1e-78 264.7 29.3 1.3e-78 264.4 20.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1467 PF07330.7 EDN95045.1 - 0.0055 16.4 0.7 0.032 14.0 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1467) UPF0193 PF05250.6 EDN95046.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) RVT_1 PF00078.22 EDN95047.1 - 3.2e-34 118.1 1.7 5.4e-34 117.4 1.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN95047.1 - 3.5e-11 43.5 0.3 7.2e-10 39.3 0.1 3.0 2 1 0 2 2 2 1 RNase H DUF929 PF06053.6 EDN95049.1 - 0.008 15.2 1.4 0.0095 15.0 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF929) Wzy_C PF04932.10 EDN95049.1 - 0.02 14.6 0.1 0.022 14.5 0.1 1.0 1 0 0 1 1 1 0 O-Antigen ligase Tmemb_9 PF05434.6 EDN95049.1 - 0.066 12.9 0.5 0.073 12.8 0.3 1.1 1 0 0 1 1 1 0 TMEM9 Hamartin PF04388.7 EDN95049.1 - 0.12 10.9 0.1 0.12 10.9 0.1 1.0 1 0 0 1 1 1 0 Hamartin protein ASFV_J13L PF05568.6 EDN95049.1 - 0.2 11.1 4.8 0.22 11.0 3.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3753 PF12575.3 EDN95049.1 - 1.2 8.9 9.6 1.9 8.3 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Bunya_G2 PF03563.8 EDN95049.1 - 7.3 5.3 7.3 8.2 5.2 5.1 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Tcp11 PF05794.8 EDN95050.1 - 1.7e-51 175.3 0.1 1.7e-51 175.3 0.1 1.7 2 0 0 2 2 2 1 T-complex protein 11 BRO1 PF03097.13 EDN95051.1 - 1e-116 389.8 0.1 1e-116 389.8 0.1 1.9 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDN95051.1 - 2.2e-80 269.8 8.9 3.2e-80 269.2 6.2 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FBP PF07299.6 EDN95051.1 - 0.18 11.1 2.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Fringe PF02434.11 EDN95053.1 - 6.7e-09 35.3 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EDN95053.1 - 3.8e-05 23.0 0.0 0.0001 21.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF604 LAGLIDADG_3 PF14528.1 EDN95053.1 - 0.0012 19.0 0.0 0.0048 17.1 0.0 2.0 2 0 0 2 2 2 1 LAGLIDADG-like domain Steroid_dh PF02544.11 EDN95055.1 - 9.1e-05 22.2 0.1 0.00023 20.9 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Malate_DH PF12434.3 EDN95055.1 - 0.45 10.2 1.5 0.77 9.5 1.0 1.3 1 0 0 1 1 1 0 Malate dehydrogenase enzyme MIP PF00230.15 EDN95056.1 - 1e-46 159.2 21.6 1.3e-46 158.8 15.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fucose_iso_C PF02952.12 EDN95056.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain DUF788 PF05620.6 EDN95056.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Pkinase PF00069.20 EDN95057.1 - 1.9e-51 174.7 0.1 2.1e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN95057.1 - 8.7e-22 77.4 0.0 7.4e-20 71.0 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN95057.1 - 9.5e-07 28.0 0.0 1.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN95057.1 - 0.0023 17.6 0.1 0.0061 16.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family CFEM PF05730.6 EDN95061.1 - 1.8e-13 50.0 5.9 5.1e-13 48.6 4.1 1.8 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.10 EDN95062.1 - 2.5e-219 729.3 0.0 3.6e-219 728.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDN95062.1 - 2.1e-24 85.1 0.0 4.5e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDN95062.1 - 1.2e-16 60.9 0.5 4.8e-16 58.9 0.1 2.2 2 0 0 2 2 2 1 ATP cone domain 60KD_IMP PF02096.15 EDN95063.1 - 2.2e-21 76.4 2.2 2.8e-21 76.0 1.5 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EDN95064.1 - 6.1e-20 71.3 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN95064.1 - 2.2e-08 34.3 0.0 1.7e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDN95064.1 - 0.031 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 G_glu_transpept PF01019.16 EDN95065.1 - 6.5e-158 526.3 0.0 7.4e-158 526.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3716 PF12511.3 EDN95066.1 - 2.1e-13 49.6 4.1 3.7e-13 48.8 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) bZIP_2 PF07716.10 EDN95068.1 - 3.7e-12 45.8 10.8 6.9e-12 44.9 7.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN95068.1 - 0.00013 21.8 14.4 0.00065 19.6 10.0 2.0 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EDN95068.1 - 0.00064 19.5 2.5 0.0013 18.6 1.7 1.5 1 0 0 1 1 1 1 Haemolysin XhlA TSC22 PF01166.13 EDN95068.1 - 0.019 14.8 0.4 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 EDN95068.1 - 0.048 13.2 4.0 0.069 12.7 2.8 1.2 1 0 0 1 1 1 0 IncA protein MCC-bdg_PDZ PF10506.4 EDN95068.1 - 0.39 10.5 0.1 0.39 10.5 0.1 2.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF972 PF06156.8 EDN95068.1 - 0.84 10.0 3.1 1.1 9.5 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Dynamin_N PF00350.18 EDN95069.1 - 9.8e-13 48.2 0.0 5.4e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EDN95069.1 - 7e-08 32.4 0.2 4.4e-06 26.6 0.2 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN95069.1 - 0.00061 20.2 0.1 0.0028 18.1 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein IIGP PF05049.8 EDN95069.1 - 0.0013 17.6 3.1 0.012 14.4 0.0 2.7 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EDN95069.1 - 0.0023 18.2 2.2 0.0088 16.3 0.0 3.1 4 0 0 4 4 4 1 ABC transporter AAA_16 PF13191.1 EDN95069.1 - 0.0071 16.3 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EDN95069.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EDN95069.1 - 0.021 14.2 0.4 0.37 10.1 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDN95069.1 - 0.023 14.5 0.0 2 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN95069.1 - 0.032 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EDN95069.1 - 0.034 12.7 0.0 0.079 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.1 EDN95069.1 - 0.036 14.2 0.0 7.2 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EDN95069.1 - 0.038 14.7 3.7 4.3 8.1 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EDN95069.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EDN95069.1 - 0.056 13.1 3.4 0.71 9.5 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 EDN95069.1 - 0.15 11.8 0.1 0.15 11.8 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EDN95069.1 - 1.7 8.9 0.0 1.7 8.9 0.0 3.5 3 1 0 3 3 2 0 AAA domain CENP-N PF05238.8 EDN95070.1 - 1.3e-144 482.2 0.0 2e-144 481.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.16 EDN95071.1 - 2.2e-49 167.9 0.0 2.9e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Baculo_PEP_C PF04513.7 EDN95072.1 - 7.7e-06 25.7 101.9 0.032 14.0 4.7 12.2 2 2 8 12 12 12 7 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EDN95072.1 - 0.001 18.3 113.9 0.088 11.9 2.7 9.7 2 2 6 10 10 10 7 Reovirus sigma C capsid protein IncA PF04156.9 EDN95072.1 - 0.0013 18.4 53.5 0.02 14.4 2.8 7.9 4 2 3 8 8 8 4 IncA protein TMP_2 PF06791.8 EDN95072.1 - 0.038 13.5 0.3 0.038 13.5 0.2 6.9 3 3 2 7 7 7 0 Prophage tail length tape measure protein HisKA_3 PF07730.8 EDN95072.1 - 0.14 12.5 17.2 0.44 10.9 0.1 7.8 7 2 0 7 7 7 0 Histidine kinase FUSC-like PF12805.2 EDN95072.1 - 0.18 10.6 3.0 4.1 6.2 0.4 3.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS BLOC1_2 PF10046.4 EDN95072.1 - 7.3 6.8 61.7 0.48 10.5 4.4 12.2 4 3 9 16 16 16 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GMC_oxred_N PF00732.14 EDN95074.1 - 2.8e-70 236.8 0.1 4e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN95074.1 - 1.2e-30 106.6 0.0 2.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EDN95074.1 - 0.00028 20.8 0.1 0.00081 19.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN95074.1 - 0.00076 18.4 0.1 0.0086 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EDN95074.1 - 0.0011 17.9 0.3 0.0039 16.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EDN95074.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EDN95074.1 - 0.091 11.2 0.4 3.1 6.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EDN95074.1 - 0.12 11.2 0.5 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 EDN95075.1 - 1.7e-20 73.5 0.0 3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN95075.1 - 7.7e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN95075.1 - 0.0013 17.7 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3779 PF12621.3 EDN95076.1 - 4.2e-20 71.4 0.1 1e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein CN_hydrolase PF00795.17 EDN95076.1 - 1.1e-19 70.4 0.0 5.5e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.18 EDN95076.1 - 6.9e-15 54.7 0.9 4.1e-14 52.2 0.7 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EDN95076.1 - 2.1e-08 33.9 0.1 6.5e-08 32.3 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like Pro_CA PF00484.14 EDN95077.1 - 2.6e-30 105.4 0.1 3.4e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Rieske PF00355.21 EDN95077.1 - 0.015 14.8 0.2 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Methyltransf_32 PF13679.1 EDN95079.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmdE PF02663.9 EDN95079.1 - 0.12 12.2 0.2 0.4 10.5 0.1 1.8 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF2805 PF10985.3 EDN95080.1 - 0.083 12.8 3.0 0.095 12.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Cerato-platanin PF07249.7 EDN95081.1 - 0.0032 17.4 0.2 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 Cerato-platanin 2-oxoacid_dh PF00198.18 EDN95082.1 - 6.5e-80 267.7 0.1 8.6e-80 267.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDN95082.1 - 1.2e-18 66.4 1.6 2.4e-18 65.5 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF605 PF04652.11 EDN95082.1 - 0.0082 15.5 12.1 0.01 15.2 8.4 1.1 1 0 0 1 1 1 1 Vta1 like Biotin_lipoyl_2 PF13533.1 EDN95082.1 - 0.019 14.5 0.3 0.55 9.9 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.1 EDN95082.1 - 0.025 14.9 0.2 0.1 12.9 0.2 1.9 1 1 0 1 1 1 0 HlyD family secretion protein PRCC PF10253.4 EDN95082.1 - 0.12 13.0 13.5 0.22 12.2 9.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ndc1_Nup PF09531.5 EDN95082.1 - 0.14 10.5 7.8 0.19 10.1 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 EDN95082.1 - 0.8 7.9 7.6 1 7.5 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Neisseria_TspB PF05616.8 EDN95082.1 - 8.3 4.6 9.0 11 4.2 6.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Histone PF00125.19 EDN95084.1 - 3.1e-17 62.4 0.3 4.4e-16 58.7 0.2 2.0 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.19 EDN95085.1 - 1.1e-21 76.7 0.1 1.6e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN95085.1 - 4.2e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDN95085.1 - 0.00022 21.4 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EDN95085.1 - 0.055 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.17 EDN95086.1 - 7.4e-13 47.9 0.0 2.2e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EDN95086.1 - 1.1e-10 41.1 0.4 2.9e-10 39.7 0.3 1.8 1 0 0 1 1 1 1 G-patch domain Chromo PF00385.19 EDN95086.1 - 6.3e-05 22.5 0.0 0.00021 20.9 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.2 EDN95086.1 - 0.00048 19.9 0.2 0.0036 17.1 0.1 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 EDN95087.1 - 1.1e-79 267.5 0.0 1.5e-68 230.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 DnaJ PF00226.26 EDN95088.1 - 7.9e-27 92.7 0.3 2.2e-26 91.3 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EDN95088.1 - 8.4e-11 41.6 1.7 2.2e-10 40.3 1.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN95088.1 - 6.3e-10 38.9 2.6 2.3e-09 37.1 1.8 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN95088.1 - 1.2e-05 25.3 9.0 0.00012 22.0 1.7 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EDN95088.1 - 0.00027 21.0 11.2 0.061 13.6 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type RPT PF13446.1 EDN95088.1 - 0.0026 17.1 0.0 0.0097 15.2 0.0 2.0 2 0 0 2 2 2 1 A repeated domain in UCH-protein zf-C2H2_6 PF13912.1 EDN95088.1 - 0.0091 15.8 0.5 0.0091 15.8 0.4 2.3 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EDN95088.1 - 0.026 14.8 6.6 1.3 9.5 1.3 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger Ndc1_Nup PF09531.5 EDN95088.1 - 7.3 4.8 5.8 13 4.0 4.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.14 EDN95089.1 - 4.8e-20 72.4 0.2 6.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 SPX domain Transglut_core2 PF13369.1 EDN95090.1 - 6.6e-12 45.1 0.1 2.8e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 EDN95090.1 - 7.9e-09 35.1 0.3 2.5e-08 33.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN95090.1 - 0.00067 19.2 0.1 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Peptidase_C12 PF01088.16 EDN95091.1 - 4.1e-42 143.7 0.0 4e-30 104.5 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 TrmB PF01978.14 EDN95091.1 - 0.033 13.8 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF1918 PF08940.6 EDN95092.1 - 0.042 13.2 2.4 17 4.8 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Abhydrolase_6 PF12697.2 EDN95094.1 - 1.2e-05 25.3 0.1 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN95094.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Putative lysophospholipase p450 PF00067.17 EDN95095.1 - 8e-47 159.8 0.0 2e-43 148.5 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 Transglut_core2 PF13369.1 EDN95095.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Metallopep PF12044.3 EDN95098.1 - 7.4e-173 574.8 0.0 9.2e-173 574.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family CDP-OH_P_transf PF01066.16 EDN95098.1 - 1.3e-12 47.9 2.4 2.9e-12 46.7 1.7 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Jacalin PF01419.12 EDN95098.1 - 0.00017 21.4 0.1 0.011 15.5 0.0 2.3 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 EDN95098.1 - 0.0097 15.9 0.2 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EDN95098.1 - 0.024 14.5 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Gar1 PF04410.9 EDN95099.1 - 3.7e-42 143.3 0.7 9.9e-42 142.0 0.4 1.8 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EDN95100.1 - 5.4e-43 146.5 0.1 9e-43 145.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN95100.1 - 1.5e-16 60.1 0.1 3.4e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EDN95100.1 - 3.6e-13 49.1 0.0 7.4e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EDN95100.1 - 5.2e-12 45.4 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain PH PF00169.24 EDN95101.1 - 2.9e-05 24.1 0.0 8.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EDN95101.1 - 0.0019 15.8 0.3 0.0028 15.2 0.2 1.1 1 0 0 1 1 1 1 Prominin Benyvirus_P25 PF05744.6 EDN95102.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.0 1 0 0 1 1 1 0 Benyvirus P25/P26 protein DUF2013 PF09431.5 EDN95105.1 - 9.7e-52 174.4 6.0 9.7e-52 174.4 4.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) DnaJ PF00226.26 EDN95106.1 - 6.2e-24 83.5 5.3 1.4e-22 79.1 1.2 3.3 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EDN95106.1 - 1.3e-22 79.2 14.9 4.3e-11 42.2 0.4 5.6 4 2 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EDN95106.1 - 5.5e-21 73.2 11.7 2.5e-06 26.8 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EDN95106.1 - 6.5e-19 66.2 16.9 0.00026 20.6 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EDN95106.1 - 1.3e-17 63.3 3.4 1.4e-05 24.8 0.1 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN95106.1 - 9.7e-13 47.5 8.7 0.17 12.6 0.0 7.5 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN95106.1 - 4e-12 44.9 5.3 0.0041 16.7 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN95106.1 - 2.2e-11 44.1 13.2 1.2e-08 35.3 0.5 5.9 4 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN95106.1 - 3.1e-08 33.5 7.5 2.3 8.8 0.0 7.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN95106.1 - 7.2e-08 32.6 13.1 0.1 12.9 0.1 6.1 4 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN95106.1 - 2.3e-07 30.1 8.1 0.063 13.1 0.1 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN95106.1 - 6.6e-07 29.0 5.3 0.0093 16.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN95106.1 - 1.2e-05 25.1 13.6 0.1 12.5 0.8 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat YfiO PF13525.1 EDN95106.1 - 0.026 14.0 0.5 0.026 14.0 0.3 3.3 4 1 1 5 5 5 0 Outer membrane lipoprotein Fis1_TPR_C PF14853.1 EDN95106.1 - 1.3 9.0 10.1 4.3 7.2 0.1 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EDN95106.1 - 2.9 8.1 8.0 12 6.1 0.3 3.6 4 2 0 4 4 4 0 Alkyl sulfatase dimerisation Corona_S2 PF01601.11 EDN95107.1 - 0.065 11.3 1.3 0.13 10.2 0.5 1.7 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein Fungal_trans_2 PF11951.3 EDN95107.1 - 0.11 11.1 7.3 0.044 12.3 0.7 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain Hormone_1 PF00103.15 EDN95107.1 - 0.17 11.2 3.4 0.24 10.6 2.4 1.4 1 1 0 1 1 1 0 Somatotropin hormone family Takusan PF04822.8 EDN95107.1 - 0.2 11.4 3.5 0.32 10.7 0.3 2.6 2 0 0 2 2 2 0 Takusan CENP-F_leu_zip PF10473.4 EDN95107.1 - 0.22 11.3 9.8 0.13 12.1 0.6 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EDN95107.1 - 0.26 11.0 9.2 0.092 12.4 1.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EDN95107.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHAD PF05235.9 EDN95107.1 - 0.47 9.9 13.3 3.1 7.3 9.2 1.9 1 1 0 1 1 1 0 CHAD domain TBPIP PF07106.8 EDN95107.1 - 0.93 9.0 10.6 0.38 10.2 3.1 2.9 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EDN95107.1 - 1.6 7.0 3.4 2.1 6.6 0.5 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Snf7 PF03357.16 EDN95107.1 - 3.2 7.1 8.7 0.75 9.1 0.2 2.6 3 0 0 3 3 3 0 Snf7 Prominin PF05478.6 EDN95107.1 - 6.1 4.2 8.7 0.83 7.1 1.5 1.6 1 1 1 2 2 2 0 Prominin Pkinase PF00069.20 EDN95108.1 - 1.3e-61 208.0 0.0 1.9e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN95108.1 - 1.3e-44 152.2 0.0 2.1e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN95108.1 - 1.5e-10 40.5 0.0 3.6e-07 29.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EDN95108.1 - 0.004 16.2 0.1 0.015 14.4 0.0 2.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN95108.1 - 0.09 12.4 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPP_enzyme_N PF02776.13 EDN95110.1 - 1.3e-34 119.1 0.0 2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN95110.1 - 1.1e-26 93.2 0.0 3.1e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN95110.1 - 6.6e-14 51.7 0.5 1.9e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EDN95110.1 - 0.003 16.3 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OCC1 PF15506.1 EDN95110.1 - 0.8 9.6 4.5 7 6.6 0.2 3.1 3 0 0 3 3 3 0 OCC1 family DUF2763 PF10961.3 EDN95111.1 - 5.7 7.3 7.1 13 6.3 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) SGT1 PF07093.6 EDN95115.1 - 4.5e-153 510.7 40.3 8.1e-152 506.6 28.0 2.0 1 1 0 1 1 1 1 SGT1 protein Microtub_assoc PF07989.6 EDN95116.1 - 1.1e-26 92.3 4.3 1.1e-26 92.3 3.0 15.0 9 5 6 16 16 16 2 Microtubule associated PACT_coil_coil PF10495.4 EDN95116.1 - 2.5e-22 78.6 0.1 1.4e-21 76.2 0.0 2.5 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 EDN95116.1 - 7.9e-06 25.7 17.7 7.9e-06 25.7 12.3 13.5 1 1 11 13 13 13 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EDN95116.1 - 0.00093 19.0 19.5 0.00093 19.0 13.5 11.8 1 1 12 13 13 13 3 Tropomyosin like Nup54 PF13874.1 EDN95116.1 - 0.0041 16.8 7.0 0.0041 16.8 4.8 11.0 1 1 7 11 11 11 2 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 EDN95116.1 - 0.055 12.6 66.4 0.02 14.1 2.7 8.6 1 1 8 10 10 10 0 Reovirus sigma C capsid protein DUF2576 PF10845.3 EDN95116.1 - 5.2 6.3 9.4 4.3 6.5 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2576) Peptidase_C14 PF00656.17 EDN95117.1 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EDN95117.1 - 0.22 11.3 0.8 0.87 9.4 0.0 2.4 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Chlam_OMP3 PF03503.8 EDN95118.1 - 0.035 14.3 0.1 0.042 14.0 0.1 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 PCI_Csn8 PF10075.4 EDN95122.1 - 8.9e-45 151.9 0.0 1.3e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDN95122.1 - 1.7e-27 96.2 0.0 2.3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EDN95123.1 - 2.3e-56 189.9 0.0 8.5e-55 184.8 0.0 2.1 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Nrap PF03813.9 EDN95124.1 - 0 1118.4 0.0 2.9e-291 968.5 0.0 2.0 1 1 1 2 2 2 2 Nrap protein Cys_Met_Meta_PP PF01053.15 EDN95125.1 - 1.6e-36 125.4 0.0 2.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDN95125.1 - 0.092 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SMC_N PF02463.14 EDN95126.1 - 1e-21 77.1 12.2 6e-10 38.7 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDN95126.1 - 1.4e-06 28.7 33.8 1.4e-06 28.7 23.4 5.3 2 2 0 2 2 2 1 AAA domain SMC_hinge PF06470.8 EDN95126.1 - 9.4e-06 25.6 0.0 4.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN95126.1 - 8.4e-05 22.6 2.3 0.022 14.7 0.6 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDN95126.1 - 0.002 18.0 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF904 PF06005.7 EDN95126.1 - 0.0046 17.2 7.4 0.0046 17.2 5.1 6.9 3 2 3 6 6 6 1 Protein of unknown function (DUF904) AAA_29 PF13555.1 EDN95126.1 - 0.029 13.8 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FlaC_arch PF05377.6 EDN95126.1 - 0.08 12.8 0.1 0.08 12.8 0.1 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) COQ9 PF08511.6 EDN95127.1 - 9.2e-30 101.9 0.9 1.2e-29 101.6 0.1 1.6 2 0 0 2 2 2 1 COQ9 Peptidase_C3 PF00548.15 EDN95128.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) RRM_1 PF00076.17 EDN95129.1 - 2.3e-43 145.6 0.0 2.4e-18 65.5 0.0 4.4 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN95129.1 - 6.3e-35 118.9 0.0 4.5e-15 55.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN95129.1 - 1.4e-20 72.8 0.0 1.7e-06 27.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 EDN95129.1 - 0.0006 19.2 0.0 0.023 14.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Limkain-b1 PF11608.3 EDN95129.1 - 0.0024 17.5 0.1 14 5.5 0.0 4.1 4 1 0 4 4 4 1 Limkain b1 RRM_3 PF08777.6 EDN95129.1 - 0.0058 16.4 0.0 0.59 9.9 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif DUF1777 PF08648.7 EDN95129.1 - 0.11 12.2 21.9 0.2 11.3 15.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Med15 PF09606.5 EDN95130.1 - 0.31 9.1 24.0 0.52 8.4 16.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1754 PF08555.5 EDN95130.1 - 0.85 10.2 6.8 1.1 9.9 2.6 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) SRP14 PF02290.10 EDN95131.1 - 7.7e-13 48.1 0.2 1.7e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MIF4G PF02854.14 EDN95132.1 - 8.4e-24 84.1 1.2 9.8e-24 83.9 0.1 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EDN95132.1 - 9.1e-19 67.2 2.3 1.2e-18 66.8 0.3 2.3 2 1 0 2 2 2 1 MA3 domain Pyr_redox_dim PF02852.17 EDN95133.1 - 5.3e-42 142.3 1.4 3.4e-41 139.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EDN95133.1 - 5e-40 137.5 12.0 2.2e-38 132.1 8.3 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN95133.1 - 6.2e-24 84.2 11.3 1.9e-20 73.0 0.6 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN95133.1 - 3.6e-11 42.9 1.2 1.8e-06 27.8 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDN95133.1 - 8.3e-10 38.3 5.6 1.7e-09 37.3 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EDN95133.1 - 9.9e-10 37.8 7.6 1.1e-08 34.3 1.2 2.5 2 1 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDN95133.1 - 4.9e-09 36.5 1.1 1.2e-05 25.4 0.4 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN95133.1 - 1.9e-07 30.2 9.2 7e-07 28.4 1.9 2.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EDN95133.1 - 3.9e-07 29.4 2.6 3.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EDN95133.1 - 1.1e-06 27.4 12.2 7.6e-05 21.3 1.4 4.1 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.1 EDN95133.1 - 5.4e-06 25.5 0.6 0.043 12.7 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EDN95133.1 - 6.1e-06 25.3 18.7 0.0002 20.4 1.8 3.6 2 2 2 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDN95133.1 - 6.3e-05 22.6 2.2 0.18 11.3 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EDN95133.1 - 0.00053 19.0 1.1 0.015 14.1 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EDN95133.1 - 0.0019 17.2 10.0 0.068 12.2 0.9 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 EDN95133.1 - 0.011 15.9 2.4 5.2 7.3 0.1 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EDN95133.1 - 0.051 12.6 0.6 5.9 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 EDN95133.1 - 0.052 12.6 0.3 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EDN95133.1 - 0.17 10.4 5.1 0.052 12.1 0.5 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EDN95133.1 - 0.38 10.3 7.3 0.28 10.8 0.3 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDN95133.1 - 0.64 9.3 3.7 6.3 6.1 0.1 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain WCCH PF03716.9 EDN95134.1 - 0.12 11.8 3.5 0.35 10.3 2.4 1.8 1 0 0 1 1 1 0 WCCH motif FA_desaturase PF00487.19 EDN95135.1 - 3.8e-37 128.1 21.4 5.3e-37 127.6 14.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EDN95135.1 - 1.7e-13 50.1 0.0 3.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.3 EDN95137.1 - 2.9e-82 274.2 6.5 2.9e-82 274.2 4.5 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EDN95137.1 - 6.8e-26 90.4 0.1 4.2e-18 65.5 0.0 4.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDN95137.1 - 1.8e-07 31.4 5.4 0.0058 17.0 0.1 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EDN95137.1 - 4.6e-07 29.3 0.4 0.098 12.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EDN95137.1 - 0.0021 18.2 4.2 0.63 10.3 0.1 5.0 5 1 0 5 5 5 1 HEAT repeats Arm PF00514.18 EDN95137.1 - 0.042 13.6 0.2 61 3.6 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Metalloenzyme PF01676.13 EDN95140.1 - 8.8e-71 238.2 0.2 1e-70 238.0 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EDN95140.1 - 1.3e-70 237.2 0.0 1.8e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EDN95140.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN95140.1 - 9.9e-06 24.9 0.0 3.1e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Med9 PF07544.8 EDN95141.1 - 1.1e-22 79.5 0.0 1.8e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF16 PF01519.11 EDN95141.1 - 0.15 12.3 1.2 0.19 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 TBCC PF07986.7 EDN95142.1 - 6.6e-33 112.6 0.2 1.3e-32 111.7 0.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Tim17 PF02466.14 EDN95143.1 - 2.8e-07 30.6 5.6 4.2e-07 30.0 3.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TFIIF_alpha PF05793.7 EDN95143.1 - 0.059 11.7 0.9 0.079 11.3 0.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UCH PF00443.24 EDN95144.1 - 2.8e-43 147.9 0.1 7.3e-43 146.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EDN95144.1 - 1.5e-37 126.8 4.7 7.4e-13 47.7 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EDN95144.1 - 3.6e-15 56.1 0.7 1.2e-06 28.1 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PCMT PF01135.14 EDN95146.1 - 2.9e-45 154.3 0.0 8.5e-30 103.8 0.0 2.0 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EDN95146.1 - 8.4e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN95146.1 - 8.4e-05 23.1 0.0 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN95146.1 - 0.0003 20.4 0.1 0.00069 19.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDN95146.1 - 0.0063 16.1 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN95146.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EDN95146.1 - 0.047 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SR-25 PF10500.4 EDN95146.1 - 0.05 13.0 4.1 0.073 12.5 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RrnaAD PF00398.15 EDN95146.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EDN95146.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GA PF01468.12 EDN95148.1 - 0.053 13.6 0.6 0.065 13.3 0.4 1.2 1 0 0 1 1 1 0 GA module ELYS PF13934.1 EDN95149.1 - 3.1e-63 213.5 0.1 4.1e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EDN95150.1 - 4.3e-73 245.1 21.1 7.4e-72 241.1 14.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN95150.1 - 2.8e-13 50.4 4.2 1.1e-05 25.5 0.4 3.3 2 2 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 EDN95150.1 - 1e-10 41.5 0.0 4.3e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 EDN95150.1 - 7.8e-06 25.2 32.6 0.00065 18.9 2.4 5.0 2 2 2 4 4 4 4 Reovirus sigma C capsid protein IncA PF04156.9 EDN95150.1 - 3.6e-05 23.4 11.8 3.6e-05 23.4 8.2 7.4 3 2 5 8 8 8 4 IncA protein AAA_29 PF13555.1 EDN95150.1 - 0.00019 20.9 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DivIC PF04977.10 EDN95150.1 - 0.00028 20.3 2.3 0.00028 20.3 1.6 11.7 6 3 7 13 13 13 1 Septum formation initiator Tropomyosin_1 PF12718.2 EDN95150.1 - 0.0017 18.2 13.7 0.0017 18.2 9.5 8.0 2 2 5 8 8 6 1 Tropomyosin like AAA_13 PF13166.1 EDN95150.1 - 0.023 13.1 100.0 0.029 12.8 7.6 5.7 3 2 3 6 6 6 0 AAA domain DUF869 PF05911.6 EDN95150.1 - 0.48 8.5 95.2 0.0078 14.5 24.5 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) APG6 PF04111.7 EDN95150.1 - 1.1 8.2 118.8 0.21 10.5 9.2 6.7 2 2 3 6 6 6 0 Autophagy protein Apg6 Halo_GVPC PF05465.8 EDN95150.1 - 5 7.1 7.0 41 4.2 0.0 3.9 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat MVL PF12151.3 EDN95151.1 - 0.16 11.6 1.5 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Mannan-binding protein Abhydrolase_6 PF12697.2 EDN95152.1 - 1.2e-25 90.7 0.0 1.4e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN95152.1 - 1.3e-08 34.7 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxysterol_BP PF01237.13 EDN95153.1 - 2.9e-58 197.0 0.0 1.4e-55 188.2 0.0 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein CP2 PF04516.10 EDN95155.1 - 3.8e-68 229.0 0.0 1.8e-66 223.5 0.0 2.3 1 1 0 1 1 1 1 CP2 transcription factor TMF_DNA_bd PF12329.3 EDN95155.1 - 0.01 15.6 0.4 0.018 14.8 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_G PF02306.10 EDN95155.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Major spike protein (G protein) Tektin PF03148.9 EDN95155.1 - 0.091 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Tektin family Kinesin PF00225.18 EDN95156.1 - 2.1e-81 273.2 0.2 3.6e-81 272.4 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 EDN95156.1 - 0.00083 19.2 0.0 0.0039 17.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EDN95156.1 - 0.00084 18.9 0.1 1.8 8.3 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EDN95156.1 - 0.1 12.7 0.2 2.4 8.3 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix domain DUF1423 PF07227.6 EDN95156.1 - 0.96 8.0 5.2 1.5 7.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) ABC_tran PF00005.22 EDN95157.1 - 2.3e-26 92.7 0.0 2.6e-18 66.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN95157.1 - 4e-22 78.9 23.1 2.7e-16 59.7 4.6 3.5 2 2 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN95157.1 - 3.9e-09 36.0 0.9 9e-05 21.7 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN95157.1 - 2e-06 28.0 1.4 0.015 15.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EDN95157.1 - 3.4e-05 23.6 0.9 0.16 11.8 0.0 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EDN95157.1 - 3.4e-05 22.9 0.2 6.4e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EDN95157.1 - 0.00056 20.3 0.2 0.0013 19.0 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN95157.1 - 0.00087 19.4 0.5 1.5 9.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN95157.1 - 0.0015 18.7 0.6 0.066 13.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EDN95157.1 - 0.0052 16.5 0.1 0.017 14.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EDN95157.1 - 0.008 15.8 0.1 0.052 13.2 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EDN95157.1 - 0.013 15.4 0.1 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN95157.1 - 0.022 14.2 0.1 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MutS_V PF00488.16 EDN95157.1 - 0.023 14.1 0.2 0.13 11.6 0.0 2.3 3 0 0 3 3 3 0 MutS domain V AAA_29 PF13555.1 EDN95157.1 - 0.023 14.2 0.1 0.061 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EDN95157.1 - 0.023 13.8 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EDN95157.1 - 0.026 13.9 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EDN95157.1 - 0.029 13.0 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.1 EDN95157.1 - 0.03 14.3 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 EDN95157.1 - 0.031 12.8 0.3 5.2 5.5 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NACHT PF05729.7 EDN95157.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EDN95157.1 - 0.049 13.0 0.2 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_11 PF13086.1 EDN95157.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EDN95157.1 - 0.085 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EDN95157.1 - 0.095 12.8 0.0 0.29 11.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase RNA12 PF10443.4 EDN95157.1 - 0.1 11.1 0.8 0.27 9.6 0.0 2.0 3 0 0 3 3 3 0 RNA12 protein AAA_30 PF13604.1 EDN95157.1 - 0.15 11.6 0.1 0.48 9.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EDN95157.1 - 0.27 10.2 0.0 0.9 8.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Rsa3 PF14615.1 EDN95159.1 - 1e-19 69.5 0.1 1.6e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 ubiquitin PF00240.18 EDN95160.1 - 7.8e-35 118.0 0.7 1.3e-34 117.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EDN95160.1 - 8.6e-28 95.9 2.1 1.8e-27 94.8 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EDN95160.1 - 7.9e-20 70.3 0.7 1.4e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN95160.1 - 1e-05 25.6 0.1 4.7e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN95160.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN95160.1 - 0.001 18.8 0.5 0.0022 17.8 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN95160.1 - 0.0049 17.0 0.4 0.0068 16.5 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EDN95160.1 - 0.022 14.6 0.3 0.037 13.8 0.2 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EDN95160.1 - 0.062 13.3 0.2 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 EDN95160.1 - 0.065 11.8 0.2 0.07 11.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 EDN95160.1 - 0.25 9.6 2.0 4.9 5.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Ribosomal_S26e PF01283.14 EDN95161.1 - 3.1e-50 169.1 9.6 3.7e-50 168.9 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EDN95161.1 - 0.042 14.2 0.7 1.6 9.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EDN95161.1 - 0.054 13.8 0.3 5.5 7.4 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 EDN95161.1 - 0.14 11.5 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) RINT1_TIP1 PF04437.8 EDN95162.1 - 0.0028 16.3 0.1 0.003 16.1 0.1 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family RINT1_TIP1 PF04437.8 EDN95163.1 - 8.5e-52 176.3 0.2 8.5e-52 176.3 0.2 2.6 3 0 0 3 3 3 1 RINT-1 / TIP-1 family ADIP PF11559.3 EDN95163.1 - 0.93 9.3 10.2 0.19 11.6 4.5 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EDN95163.1 - 1.5 8.9 9.1 3.3 7.7 3.4 2.5 2 0 0 2 2 2 0 DivIVA protein NifQ PF04891.7 EDN95163.1 - 2.5 8.2 7.0 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 NifQ Snapin_Pallidin PF14712.1 EDN95163.1 - 6.4 7.1 9.5 1 9.7 2.0 2.9 3 1 0 3 3 3 0 Snapin/Pallidin DNA_ligase_A_M PF01068.16 EDN95164.1 - 9.8e-47 158.9 0.3 5.6e-44 149.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDN95164.1 - 4.4e-40 137.3 0.1 9.9e-40 136.2 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDN95164.1 - 4.6e-18 65.4 0.0 2.1e-17 63.2 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region SprT-like PF10263.4 EDN95165.1 - 1.8e-49 167.4 2.8 2.7e-49 166.8 1.9 1.3 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EDN95165.1 - 0.0058 16.8 0.3 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box Peptidase_MA_2 PF13485.1 EDN95165.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily SPT6_acidic PF14632.1 EDN95165.1 - 1.1 9.5 19.6 0.024 14.8 7.9 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Mog1 PF04603.7 EDN95166.1 - 5e-18 65.3 0.0 8e-18 64.7 0.0 1.3 1 1 0 1 1 1 1 Ran-interacting Mog1 protein ELMO_CED12 PF04727.8 EDN95167.1 - 0.05 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 ELMO/CED-12 family HIT PF01230.18 EDN95168.1 - 1.8e-17 63.6 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDN95168.1 - 1.4e-09 38.1 0.0 2.3e-09 37.4 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDN95168.1 - 0.00063 19.3 0.1 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EDN95169.1 - 6.9e-34 116.6 0.0 8.9e-24 83.7 0.0 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN95169.1 - 9.2e-15 54.5 0.0 3.4e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDN95169.1 - 1.8e-05 24.6 0.0 0.00045 20.1 0.0 2.5 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EDN95170.1 - 8.2e-29 99.1 2.0 1.3e-28 98.5 1.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.3 EDN95171.1 - 1.5e-09 37.6 0.9 1.5e-09 37.6 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN95171.1 - 3.7e-05 23.7 2.8 0.0011 19.1 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN95171.1 - 0.0046 17.0 0.3 0.0069 16.4 0.2 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EDN95171.1 - 0.02 15.1 0.6 0.29 11.5 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EDN95171.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF3279 PF11682.3 EDN95171.1 - 0.071 12.6 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Prim_Zn_Ribbon PF08273.7 EDN95171.1 - 0.15 12.2 0.1 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Aconitase PF00330.15 EDN95172.1 - 1.2e-176 587.8 0.1 4.3e-176 585.9 0.0 1.9 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN95172.1 - 1.7e-46 157.5 0.0 3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.17 EDN95173.1 - 2.3e-14 53.6 13.6 2.3e-14 53.6 9.5 1.6 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EDN95174.1 - 8e-101 338.2 1.3 1.1e-100 337.8 0.9 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EDN95175.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 PCI domain NAD_binding_10 PF13460.1 EDN95176.1 - 2.2e-19 70.1 0.0 3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN95176.1 - 2.7e-17 62.8 0.0 3.4e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EDN95176.1 - 4.9e-16 58.8 0.1 1.6e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN95176.1 - 7.1e-12 44.6 0.0 1.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN95176.1 - 1.4e-11 43.8 0.0 1.5e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EDN95176.1 - 8.2e-07 28.1 0.2 0.00067 18.6 0.1 3.1 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EDN95176.1 - 0.0005 19.1 0.0 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EDN95176.1 - 0.0021 18.0 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase DDE_Tnp_1_3 PF13612.1 EDN95176.1 - 0.013 15.2 0.0 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Polysacc_synt_2 PF02719.10 EDN95176.1 - 0.035 13.0 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 EDN95176.1 - 0.047 13.3 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 KR domain N6-adenineMlase PF10237.4 EDN95177.1 - 1.4e-20 73.5 0.6 1.2e-12 47.7 0.1 2.2 1 1 1 2 2 2 2 Probable N6-adenine methyltransferase Ycf54 PF10674.4 EDN95177.1 - 0.13 12.4 0.1 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Lactamase_B PF00753.22 EDN95178.1 - 4.9e-08 32.8 3.3 7.4e-08 32.2 2.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily UCH PF00443.24 EDN95179.1 - 2.4e-52 177.7 4.8 7.7e-52 176.0 3.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN95179.1 - 1.2e-31 110.3 12.5 9.4e-31 107.3 8.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDN95179.1 - 4.8e-05 23.3 0.2 4.8e-05 23.3 0.1 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Ytp1 PF10355.4 EDN95180.1 - 1.3e-113 378.7 13.1 2.1e-113 378.0 9.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDN95180.1 - 6.3e-34 115.7 2.6 6.3e-34 115.7 1.8 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) ADH_zinc_N PF00107.21 EDN95181.1 - 1.1e-23 83.1 0.0 1.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_28 PF00295.12 EDN95182.1 - 1.7e-85 286.8 15.9 2.1e-85 286.5 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EDN95182.1 - 0.18 11.5 48.2 1.3e+03 -1.1 33.4 3.3 1 1 0 1 1 1 0 Right handed beta helix region DDE_1 PF03184.14 EDN95185.1 - 1.7e-14 53.5 0.0 4.7e-13 48.7 0.0 2.0 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95185.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RTA1 PF04479.8 EDN95186.1 - 1.5e-17 63.8 3.2 1.8e-17 63.6 2.2 1.0 1 0 0 1 1 1 1 RTA1 like protein Claudin_2 PF13903.1 EDN95186.1 - 0.31 10.7 4.2 0.19 11.3 1.6 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TPT PF03151.11 EDN95186.1 - 3 7.4 10.4 0.15 11.6 1.8 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Fungal_trans_2 PF11951.3 EDN95187.1 - 5.5e-05 21.9 0.4 7.1e-05 21.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WBP-1 PF11669.3 EDN95187.1 - 0.026 14.5 0.3 0.048 13.7 0.2 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 NmrA PF05368.8 EDN95188.1 - 2.7e-26 92.2 0.0 2.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN95188.1 - 4.7e-12 46.2 1.9 1.6e-11 44.5 1.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN95188.1 - 0.0011 18.4 0.5 0.068 12.5 0.3 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDN95188.1 - 0.033 14.1 2.0 0.068 13.0 1.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EDN95188.1 - 0.12 11.0 0.2 0.24 10.0 0.2 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sporozoite_P67 PF05642.6 EDN95189.1 - 0.52 8.1 1.9 0.7 7.6 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Amidohydro_1 PF01979.15 EDN95191.1 - 9.4e-21 74.8 0.1 2.7e-11 43.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EDN95191.1 - 8.1e-17 62.1 0.2 9.6e-16 58.6 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EDN95191.1 - 7.2e-10 38.5 0.1 1.6e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDN95191.1 - 5.1e-08 32.5 0.2 6e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidase PF01425.16 EDN95192.1 - 4.6e-56 190.5 1.9 8.8e-49 166.5 1.0 3.0 1 1 0 2 2 2 2 Amidase Glyco_transf_20 PF00982.16 EDN95192.1 - 0.15 10.5 0.2 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 20 DDE_1 PF03184.14 EDN95194.1 - 3e-51 173.6 0.0 9.9e-51 171.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN95194.1 - 5e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95194.1 - 1.2e-12 47.1 3.0 7e-12 44.7 0.4 2.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN95194.1 - 4.5e-11 42.4 0.2 1.4e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN95194.1 - 0.0088 16.1 0.1 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain NUMOD1 PF07453.8 EDN95194.1 - 0.12 12.2 0.2 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain COG5 PF10392.4 EDN95195.1 - 1.8e-40 137.9 0.6 1.8e-40 137.9 0.4 2.6 2 1 0 2 2 2 1 Golgi transport complex subunit 5 SPX PF03105.14 EDN95195.1 - 0.17 11.6 2.2 0.51 10.0 1.5 1.8 1 1 0 1 1 1 0 SPX domain DUF2434 PF10361.4 EDN95196.1 - 1.1e-131 438.3 6.3 1.3e-131 438.0 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF2516 PF10724.4 EDN95196.1 - 0.11 12.5 0.3 0.11 12.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) PalH PF08733.5 EDN95196.1 - 0.35 9.6 3.5 0.19 10.5 1.0 1.6 2 0 0 2 2 2 0 PalH/RIM21 Corona_nucleoca PF00937.13 EDN95201.1 - 0.73 8.7 3.7 0.8 8.5 2.6 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3965 PF13112.1 EDN95202.1 - 0.017 14.3 0.0 0.019 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) Peptidase_M13 PF01431.16 EDN95203.1 - 0.13 11.4 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 DUF3317 PF11779.3 EDN95204.1 - 0.1 12.0 0.8 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Zn_clus PF00172.13 EDN95205.1 - 4.1e-09 36.2 11.6 6.6e-09 35.5 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EDN95205.1 - 0.0085 15.6 5.5 0.03 13.9 3.8 2.0 1 0 0 1 1 1 1 AT hook motif Glyco_hydro_16 PF00722.16 EDN95205.1 - 0.1 11.8 0.6 0.2 10.9 0.4 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 RVT_1 PF00078.22 EDN95206.1 - 5.6e-38 130.4 0.0 1e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN95206.1 - 2.7e-15 56.0 0.4 1.5e-14 53.6 0.2 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN95206.1 - 3.7e-15 56.4 0.0 7.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN95206.1 - 7.2e-05 22.8 0.3 0.00016 21.7 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3285 PF11688.3 EDN95208.1 - 0.15 11.6 0.0 0.74 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Myb_DNA-bind_6 PF13921.1 EDN95210.1 - 0.0082 16.2 0.1 0.024 14.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Acetyltransf_13 PF13880.1 EDN95211.1 - 5e-17 61.3 0.0 1e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EDN95211.1 - 1e-13 50.5 1.5 2.1e-13 49.6 1.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EDN95211.1 - 3.3e-06 27.0 0.0 9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN95211.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain polyprenyl_synt PF00348.12 EDN95212.1 - 5.8e-31 107.2 0.1 6.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.3 EDN95212.1 - 0.074 12.7 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Thymosin PF01290.15 EDN95212.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Thymosin beta-4 family Vma12 PF11712.3 EDN95213.1 - 5.5e-40 136.3 1.6 2.3e-39 134.3 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF572 PF04502.8 EDN95213.1 - 0.02 14.0 3.8 0.033 13.4 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3366 PF11846.3 EDN95213.1 - 0.051 13.4 1.3 0.35 10.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) DUF1469 PF07332.6 EDN95213.1 - 0.07 12.8 2.4 0.15 11.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) ATXN-1_C PF12547.3 EDN95216.1 - 0.0073 16.2 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Capicua transcriptional repressor modulator zf-CCHC PF00098.18 EDN95216.1 - 0.31 11.0 4.0 0.47 10.4 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN95216.1 - 0.61 9.7 3.1 1.6 8.4 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle HTH_psq PF05225.11 EDN95217.1 - 1.6e-06 27.5 0.0 2.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain ATP_bind_4 PF01902.12 EDN95217.1 - 0.021 14.2 0.2 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 ATP-binding region HTH_8 PF02954.14 EDN95217.1 - 1.1 8.7 4.2 0.38 10.3 0.2 2.3 2 1 0 2 2 2 0 Bacterial regulatory protein, Fis family DDE_1 PF03184.14 EDN95218.1 - 1.2e-13 50.7 0.0 1.3e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-binding PF00249.26 EDN95219.1 - 6.4e-14 51.7 7.7 2e-09 37.3 0.2 4.2 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN95219.1 - 1.8e-13 50.3 8.6 2.8e-10 40.1 1.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EDN95219.1 - 0.03 14.5 5.2 4.6 7.5 0.1 4.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EDN95219.1 - 0.34 10.8 6.1 1.1 9.2 0.1 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Abhydrolase_6 PF12697.2 EDN95220.1 - 7.6e-24 84.8 0.0 1.6e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN95220.1 - 2.3e-11 43.6 0.0 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN95220.1 - 1.3e-10 41.1 0.0 4.6e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 EDN95221.1 - 9.3e-07 29.0 1.0 9.2e-06 25.7 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EDN95221.1 - 0.00013 21.7 0.1 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EDN95221.1 - 0.013 14.9 0.0 0.042 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDN95221.1 - 0.026 14.0 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN95221.1 - 0.033 14.3 0.1 0.1 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDN95221.1 - 0.037 12.9 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EDN95221.1 - 0.091 12.4 0.1 1 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EDN95221.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EDN95221.1 - 0.13 12.7 0.3 2 8.9 0.2 2.6 1 1 0 1 1 1 0 Miro-like protein Alpha-amylase PF00128.19 EDN95224.1 - 8.3e-94 314.5 0.0 1.3e-93 313.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EDN95224.1 - 0.0022 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 EDN95224.1 - 0.0025 17.8 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Gly-zipper_Omp PF13488.1 EDN95228.1 - 0.062 12.9 2.3 0.11 12.1 1.6 1.4 1 0 0 1 1 1 0 Glycine zipper EMG1 PF03587.9 EDN95230.1 - 1.7e-78 262.5 0.0 1.9e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RVT_2 PF07727.9 EDN95233.1 - 1.7e-19 69.7 0.0 2.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN95233.1 - 0.00022 21.2 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AA_permease_2 PF13520.1 EDN95237.1 - 1.8e-55 188.1 55.0 2.3e-55 187.8 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN95237.1 - 7.9e-15 54.1 45.1 1.2e-14 53.5 31.3 1.2 1 0 0 1 1 1 1 Amino acid permease Renin_r PF07850.9 EDN95237.1 - 4.9 7.5 6.0 0.79 10.1 0.3 2.6 2 1 0 2 2 2 0 Renin receptor-like protein RVT_1 PF00078.22 EDN95249.1 - 1.9e-26 92.7 0.0 2.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRJP PF03022.11 EDN95250.1 - 5.1e-12 45.5 0.0 9.2e-12 44.7 0.0 1.4 2 0 0 2 2 2 1 Major royal jelly protein NHL PF01436.16 EDN95250.1 - 1.4 9.0 4.3 35 4.5 0.0 3.8 4 0 0 4 4 4 0 NHL repeat RRF PF01765.14 EDN95251.1 - 0.048 13.1 0.7 0.13 11.7 0.6 1.6 2 0 0 2 2 2 0 Ribosome recycling factor Metal_resist PF13801.1 EDN95251.1 - 0.18 11.8 2.4 0.29 11.1 1.7 1.4 1 0 0 1 1 1 0 Heavy-metal resistance UDP-g_GGTase PF06427.6 EDN95253.1 - 3.3e-63 212.8 0.0 6.7e-63 211.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EDN95253.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.9 EDN95254.1 - 5.1e-148 493.5 0.0 7.8e-148 492.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EDN95254.1 - 1.4e-86 290.7 0.0 1.9e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EDN95254.1 - 1.3e-47 158.0 14.1 1.2e-08 34.5 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDN95254.1 - 0.0048 15.0 5.9 0.73 7.8 0.0 3.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Clathrin PF00637.15 EDN95254.1 - 0.0081 15.7 1.5 0.14 11.7 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EDN95255.1 - 1.2e-06 28.2 1.4 0.0016 18.2 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1917 PF08939.5 EDN95256.1 - 4.8e-83 278.6 0.0 6.2e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TrmB PF01978.14 EDN95256.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TLD PF07534.11 EDN95257.1 - 2.7e-16 59.8 0.2 3.4e-15 56.2 0.1 2.1 1 1 0 1 1 1 1 TLD HEM4 PF02602.10 EDN95258.1 - 3.9e-31 108.0 0.0 4.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.8 EDN95259.1 - 2.3e-27 94.7 2.8 2.3e-27 94.7 1.9 1.8 2 0 0 2 2 2 1 Erv1 / Alr family LCAT PF02450.10 EDN95260.1 - 1e-95 320.9 0.0 1.4e-95 320.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EDN95260.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EDN95260.1 - 0.0025 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN95260.1 - 0.0095 15.8 0.0 0.078 12.8 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN95260.1 - 0.069 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Cnd1_N PF12922.2 EDN95261.1 - 7.9e-60 201.3 0.8 6.4e-59 198.4 0.5 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EDN95261.1 - 1.3e-54 184.7 3.4 3.8e-51 173.4 1.3 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDN95261.1 - 3.3e-11 43.3 4.4 6.4e-05 23.1 0.0 5.9 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.17 EDN95261.1 - 6.2e-09 35.2 9.1 0.036 14.1 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EDN95261.1 - 2.3e-05 24.7 5.3 0.53 10.8 0.0 6.0 5 1 1 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EDN95261.1 - 0.012 15.5 1.6 5.1 7.1 0.2 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 EDN95262.1 - 3.3e-42 144.4 0.0 4.1e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN95262.1 - 1.3e-12 47.3 0.0 3.9e-08 32.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EDN95262.1 - 8.4e-05 22.4 0.0 0.031 13.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN95262.1 - 0.02 13.8 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Ribosomal_L18e PF00828.14 EDN95263.1 - 8.1e-34 116.7 0.0 1.1e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MFS_1 PF07690.11 EDN95266.1 - 1.5e-22 79.8 66.5 2.8e-19 69.0 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dexa_ind PF15198.1 EDN95266.1 - 0.17 11.8 3.8 0.12 12.2 0.4 2.3 2 0 0 2 2 2 0 Dexamethasone-induced YqzM PF14141.1 EDN95266.1 - 4.9 7.0 10.0 8.4 6.2 0.2 3.2 2 1 0 3 3 3 0 YqzM-like protein Zn_clus PF00172.13 EDN95269.1 - 3.5e-08 33.2 8.6 5.8e-08 32.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN95269.1 - 7.6e-05 21.7 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain BAF1_ABF1 PF04684.8 EDN95269.1 - 2.6 6.8 9.4 4.1 6.1 6.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cu_amine_oxid PF01179.15 EDN95270.1 - 1.4e-168 560.9 0.2 1.7e-168 560.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EDN95270.1 - 6.2e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CPSF100_C PF13299.1 EDN95272.1 - 2.6e-43 148.0 0.2 2.6e-43 148.0 0.1 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EDN95272.1 - 5e-27 94.3 0.0 1.9e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EDN95272.1 - 7.2e-05 22.5 0.0 0.00021 21.0 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EDN95272.1 - 0.064 12.8 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Sec23_trunk PF04811.10 EDN95273.1 - 1.9e-54 184.5 0.0 5.5e-54 183.0 0.0 1.8 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN95273.1 - 1.4e-24 85.4 0.0 2.4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDN95273.1 - 1.7e-18 66.9 0.0 2.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDN95273.1 - 4.9e-17 61.1 5.1 1e-16 60.2 3.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDN95273.1 - 1.5e-07 31.0 0.0 3.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat C6 PF01681.12 EDN95274.1 - 0.0046 16.9 0.0 1.9 8.6 0.0 2.1 2 0 0 2 2 2 2 C6 domain SAM_1 PF00536.25 EDN95275.1 - 0.098 12.8 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2263 PF10021.4 EDN95277.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.15 EDN95278.1 - 4.6e-34 117.6 0.0 5.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Gti1_Pac2 PF09729.4 EDN95280.1 - 3.4e-49 166.9 3.7 1.5e-48 164.8 0.1 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family FAM194 PF14977.1 EDN95281.1 - 0.072 12.0 0.0 0.087 11.7 0.0 1.0 1 0 0 1 1 1 0 FAM194 protein PMR5N PF14416.1 EDN95283.1 - 0.03 14.3 0.3 0.082 12.9 0.2 1.7 1 1 0 1 1 1 0 PMR5 N terminal Domain HET PF06985.6 EDN95284.1 - 2.5e-19 69.8 0.2 1e-18 67.8 0.2 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SYS1 PF09801.4 EDN95286.1 - 1.1e-52 177.8 9.2 1.3e-52 177.6 6.4 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network FeoB_C PF07664.7 EDN95286.1 - 0.19 11.1 2.3 1 8.8 0.4 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus HET PF06985.6 EDN95288.1 - 2.4e-25 89.3 0.1 6.2e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 EDN95289.1 - 0.001 17.7 0.1 0.073 11.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Autophagy_Cterm PF10381.4 EDN95290.1 - 0.12 11.5 0.3 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Tmemb_9 PF05434.6 EDN95292.1 - 0.0081 15.9 0.0 0.0094 15.7 0.0 1.0 1 0 0 1 1 1 1 TMEM9 NinG PF05766.7 EDN95292.1 - 0.18 11.5 4.3 0.2 11.4 3.0 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein MMtag PF10159.4 EDN95292.1 - 4.9 7.2 13.5 8.6 6.4 0.4 2.2 2 0 0 2 2 2 0 Kinase phosphorylation protein DUF2011 PF09428.5 EDN95292.1 - 6.6 6.6 16.6 8 6.3 11.5 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) CAF-1_p150 PF11600.3 EDN95292.1 - 9.4 5.5 21.7 11 5.3 15.0 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2749 PF10907.3 EDN95294.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2749) DUF1049 PF06305.6 EDN95294.1 - 0.0061 16.0 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Bac_Ubq_Cox PF01654.12 EDN95294.1 - 0.12 10.7 1.0 0.15 10.3 0.7 1.1 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase DUF1191 PF06697.7 EDN95294.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SCIMP PF15050.1 EDN95294.1 - 0.6 10.0 3.9 0.26 11.1 0.3 1.9 1 1 1 2 2 2 0 SCIMP protein NAD_binding_6 PF08030.7 EDN95295.1 - 3.7e-32 111.3 0.0 6.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN95295.1 - 1.6e-18 66.4 0.0 4.3e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN95295.1 - 6.1e-17 61.8 17.6 1.9e-16 60.3 7.0 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EDN95295.1 - 0.00042 20.4 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UQ_con PF00179.21 EDN95296.1 - 1.3e-51 173.7 0.0 1.4e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN95296.1 - 4.1e-05 23.3 0.0 4.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN95296.1 - 0.0035 17.2 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EDN95296.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_1 PF00441.19 EDN95297.1 - 2.9e-25 89.1 0.1 4.7e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN95297.1 - 1.6e-22 80.2 0.1 3.3e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EDN95297.1 - 5e-18 64.3 0.0 1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EDN95297.1 - 6.5e-06 26.4 0.1 1.1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_N PF00752.12 EDN95298.1 - 4.6e-23 81.4 0.2 1.1e-21 76.9 0.0 2.9 2 1 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EDN95298.1 - 8.8e-15 54.5 3.8 9.5e-07 28.7 0.1 3.2 3 1 1 4 4 4 2 XPG I-region 5_3_exonuc PF01367.15 EDN95298.1 - 0.00016 21.8 0.5 0.00051 20.2 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 EDN95298.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain TniB PF05621.6 EDN95298.1 - 0.081 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein HHH_2 PF12826.2 EDN95298.1 - 0.14 12.0 0.0 0.48 10.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HXXSHH PF07586.6 EDN95298.1 - 0.78 8.6 4.8 1.2 7.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) RNase_H2-Ydr279 PF09468.5 EDN95298.1 - 2.7 7.1 10.7 4.4 6.4 7.0 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF3915 PF13054.1 EDN95301.1 - 0.28 11.1 1.6 0.3 11.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Linker_histone PF00538.14 EDN95302.1 - 7.5e-13 48.3 2.0 1.3e-12 47.5 0.2 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family Acetyltransf_7 PF13508.1 EDN95304.1 - 6.7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN95304.1 - 2e-05 24.5 0.1 6.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDN95304.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN95304.1 - 0.039 13.6 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 FR47-like protein Pox_polyA_pol PF03296.8 EDN95306.1 - 0.016 14.7 0.0 0.016 14.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Sugar_tr PF00083.19 EDN95307.1 - 2.2e-43 148.4 25.8 3.1e-43 148.0 17.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN95307.1 - 1.8e-18 66.4 25.4 1.8e-18 66.4 17.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily PhzC-PhzF PF02567.11 EDN95308.1 - 5.9e-36 124.1 0.0 1e-35 123.3 0.0 1.4 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_11 PF13720.1 EDN95309.1 - 0.31 11.2 5.1 5.4 7.3 0.1 4.3 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Baculo_PEP_C PF04513.7 EDN95309.1 - 0.46 10.3 3.7 16 5.3 0.2 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDE_1 PF03184.14 EDN95311.1 - 1.8e-47 161.2 0.1 5.2e-47 159.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95311.1 - 4e-10 39.3 1.1 1.2e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN95311.1 - 3.8e-06 26.7 0.0 7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M14 PF00246.19 EDN95312.1 - 3.3e-72 243.4 0.2 5.4e-72 242.7 0.0 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EDN95312.1 - 3.7e-10 39.3 0.1 7.9e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide ABC_tran PF00005.22 EDN95313.1 - 1.7e-31 109.3 0.0 4e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN95313.1 - 9.6e-23 80.9 18.9 1.3e-16 60.8 12.1 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN95313.1 - 1.9e-09 37.0 0.0 0.00053 19.2 0.0 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN95313.1 - 4.9e-06 26.7 8.7 0.046 13.6 0.0 3.9 3 1 1 4 4 4 3 AAA domain AAA_23 PF13476.1 EDN95313.1 - 0.0003 21.1 0.6 0.00064 20.1 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN95313.1 - 0.001 19.2 0.2 0.45 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDN95313.1 - 0.0014 17.7 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 EDN95313.1 - 0.0022 16.9 0.0 0.0089 14.9 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 EDN95313.1 - 0.0042 16.9 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EDN95313.1 - 0.0051 16.2 0.0 0.028 13.8 0.0 2.2 3 0 0 3 3 3 1 AAA-like domain AIG1 PF04548.11 EDN95313.1 - 0.03 13.4 0.2 0.14 11.2 0.0 2.1 3 0 0 3 3 3 0 AIG1 family FtsK_SpoIIIE PF01580.13 EDN95313.1 - 0.035 13.5 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EDN95313.1 - 0.084 12.4 0.1 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDN95313.1 - 0.18 11.7 0.4 0.49 10.3 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase Meth_synt_2 PF01717.13 EDN95314.1 - 3.6e-16 59.0 0.0 5.6e-09 35.4 0.0 2.9 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDN95314.1 - 2.3e-05 23.8 0.3 0.06 12.6 0.1 3.1 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Metallophos_2 PF12850.2 EDN95315.1 - 0.016 15.0 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EDN95315.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos PF00149.23 EDN95316.1 - 0.0011 18.4 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN95316.1 - 0.0073 16.1 0.0 0.0078 16.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNase_H PF00075.19 EDN95318.1 - 1.6e-15 57.6 0.0 3.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-C2H2 PF00096.21 EDN95322.1 - 1.6e-05 24.9 10.7 0.0084 16.3 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN95322.1 - 1.8e-05 24.7 5.2 1.8e-05 24.7 3.6 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN95322.1 - 9.2e-05 22.5 12.1 0.0049 17.1 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN95322.1 - 0.68 9.9 4.7 0.29 11.1 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Alginate_lyase2 PF08787.6 EDN95323.1 - 0.04 13.5 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 Alginate lyase Response_reg PF00072.19 EDN95324.1 - 9.7e-19 67.4 0.0 4.4e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EDN95324.1 - 1.7e-16 59.9 0.0 3.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDN95324.1 - 8.8e-13 48.0 0.1 3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DDE_1 PF03184.14 EDN95326.1 - 1.8e-32 112.2 0.0 3.2e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95326.1 - 2.3e-06 27.3 0.5 5.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN95326.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN95327.1 - 0.015 15.1 7.0 0.031 14.2 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN95327.1 - 0.16 11.6 3.6 0.31 10.7 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_20 PF00982.16 EDN95328.1 - 3.6e-146 487.3 0.0 5e-146 486.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDN95328.1 - 4.8e-81 271.1 0.0 9.6e-81 270.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EDN95328.1 - 0.012 15.2 0.0 0.062 12.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EDN95328.1 - 0.029 14.4 0.2 1.5 8.9 0.0 3.5 2 1 1 3 3 3 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EDN95328.1 - 0.053 13.0 0.1 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Epimerase PF01370.16 EDN95330.1 - 9.7e-17 61.1 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDN95330.1 - 1.2e-16 61.2 0.1 1.8e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EDN95330.1 - 1.6e-07 30.5 0.1 2.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EDN95330.1 - 1.7e-06 27.5 0.1 4.7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EDN95330.1 - 1.5e-05 23.8 0.0 9.2e-05 21.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN95330.1 - 0.0044 15.9 2.0 0.037 12.9 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN95330.1 - 0.0049 15.8 0.1 0.14 11.0 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein NUC129 PF08157.6 EDN95332.1 - 0.037 13.9 0.3 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 NUC129 domain DUF4109 PF13397.1 EDN95333.1 - 0.15 12.4 2.6 0.37 11.1 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4109) UPF0239 PF06783.6 EDN95333.1 - 8.7 6.3 6.6 28 4.7 4.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Sec62 PF03839.11 EDN95333.1 - 9.3 5.5 9.7 20 4.5 6.7 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_hydro_18 PF00704.23 EDN95335.1 - 6.3e-14 52.1 3.0 1.4e-13 51.0 0.1 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EDN95335.1 - 2e-08 33.7 11.5 2e-08 33.7 8.0 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 EDN95335.1 - 7 4.3 6.9 9.7 3.9 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Opacity PF02462.10 EDN95336.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Opacity family porin protein YjgP_YjgQ PF03739.9 EDN95337.1 - 0.48 9.1 4.3 0.54 8.9 3.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family AOX PF01786.12 EDN95338.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Alternative oxidase Pro_isomerase PF00160.16 EDN95339.1 - 3.7e-46 157.1 0.4 5e-46 156.7 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 EDN95340.1 - 5.9e-07 29.9 0.4 6e-07 29.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1521 PF07481.6 EDN95343.1 - 0.031 13.9 0.0 0.033 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) NAM-associated PF14303.1 EDN95344.1 - 0.23 11.7 3.8 0.33 11.2 2.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Herpes_UL37_1 PF03970.8 EDN95346.1 - 0.00081 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL37 tegument protein MFS_1 PF07690.11 EDN95347.1 - 3e-22 78.8 32.8 8.1e-13 47.8 13.1 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily F-box PF00646.28 EDN95348.1 - 5.1e-05 22.8 0.2 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain FAST_1 PF06743.10 EDN95348.1 - 0.21 11.3 2.8 14 5.4 0.1 3.5 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 CTP_transf_1 PF01148.15 EDN95349.1 - 8.8e-09 35.3 2.4 8.8e-09 35.3 1.7 3.1 2 2 0 2 2 2 1 Cytidylyltransferase family Glyco_transf_22 PF03901.12 EDN95351.1 - 1.4e-38 133.0 7.9 1.6e-38 132.7 5.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EDN95351.1 - 0.081 12.8 2.6 0.17 11.8 1.8 1.5 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Aminotran_3 PF00202.16 EDN95353.1 - 2.5e-110 368.5 0.0 3.1e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EDN95353.1 - 0.00023 20.4 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDN95353.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3543 PF12063.3 EDN95354.1 - 1.5e-95 318.9 0.0 2.1e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EDN95354.1 - 3.1e-61 206.7 0.0 6.9e-61 205.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN95354.1 - 1.2e-41 142.5 0.0 2.2e-41 141.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease_2 PF13520.1 EDN95356.1 - 1.1e-95 320.6 38.5 1.4e-95 320.4 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN95356.1 - 2.8e-20 72.1 35.1 4e-20 71.6 24.4 1.2 1 0 0 1 1 1 1 Amino acid permease NMO PF03060.10 EDN95358.1 - 2.1e-67 227.6 1.0 2.4e-67 227.4 0.7 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDN95358.1 - 3.2e-06 26.2 0.0 0.00018 20.5 0.0 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TIM-br_sig_trns PF09370.5 EDN95358.1 - 0.053 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 TIM-barrel signal transduction protein FMN_dh PF01070.13 EDN95358.1 - 0.087 11.6 3.6 0.14 10.9 2.5 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase cobW PF02492.14 EDN95359.1 - 1.6e-36 125.4 0.0 2.2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EDN95359.1 - 0.012 15.7 0.1 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EDN95359.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EDN95359.1 - 0.021 14.3 0.0 0.07 12.6 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EDN95359.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EDN95359.1 - 0.052 13.0 0.2 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN95359.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EDN95359.1 - 0.099 12.0 0.2 1.3 8.3 0.1 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EDN95359.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 EDN95360.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 GYF domain DUF1996 PF09362.5 EDN95362.1 - 1.5e-65 221.1 0.4 2.2e-65 220.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EDN95362.1 - 1.2e-19 70.0 12.4 2.8e-19 68.8 8.6 1.7 1 0 0 1 1 1 1 WSC domain Hep_59 PF07052.6 EDN95365.1 - 0.056 13.8 4.0 0.079 13.3 2.8 1.2 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 CDKN3 PF05706.7 EDN95365.1 - 0.12 11.8 0.3 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Daxx PF03344.10 EDN95365.1 - 0.67 8.3 16.7 0.74 8.2 11.6 1.0 1 0 0 1 1 1 0 Daxx Family Packaging_FI PF14000.1 EDN95365.1 - 0.96 9.6 8.3 1.3 9.2 5.8 1.2 1 0 0 1 1 1 0 DNA packaging protein FI Cwf_Cwc_15 PF04889.7 EDN95365.1 - 1.2 8.7 17.1 1.5 8.4 11.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 EDN95365.1 - 1.9 6.7 21.1 2.1 6.6 14.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 EDN95365.1 - 2.2 7.7 9.0 2.3 7.7 6.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-T PF15511.1 EDN95365.1 - 3.5 6.7 14.5 4.1 6.5 10.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Vfa1 PF08432.5 EDN95365.1 - 4.1 7.3 7.7 5.7 6.9 5.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2151 PF10221.4 EDN95365.1 - 4.6 5.3 6.3 5 5.1 4.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Mpp10 PF04006.7 EDN95365.1 - 7.7 4.7 23.3 8.9 4.5 16.2 1.0 1 0 0 1 1 1 0 Mpp10 protein OB_NTP_bind PF07717.11 EDN95366.1 - 6e-29 100.1 0.0 1.8e-28 98.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN95366.1 - 3.6e-21 75.0 0.0 3.6e-21 75.0 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN95366.1 - 1.4e-12 47.3 0.0 3.3e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN95366.1 - 2.5e-06 27.1 0.1 6.5e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN95366.1 - 4.5e-05 23.6 0.1 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN95366.1 - 0.0027 16.6 0.0 0.0064 15.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EDN95366.1 - 0.011 15.4 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 EDN95366.1 - 0.049 13.2 1.6 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EDN95366.1 - 0.081 12.3 0.8 0.48 9.8 0.6 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.14 EDN95366.1 - 0.13 11.6 0.1 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 EDN95366.1 - 2.3 7.9 13.1 1.6 8.5 0.0 4.0 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit Urb2 PF10441.4 EDN95368.1 - 6.6e-65 218.8 0.7 2.3e-64 217.0 0.0 2.3 3 0 0 3 3 3 1 Urb2/Npa2 family Methyltransf_12 PF08242.7 EDN95369.1 - 3.4e-16 59.5 0.0 1.3e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN95369.1 - 3.4e-12 46.5 0.0 6.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN95369.1 - 5.7e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN95369.1 - 1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN95369.1 - 1.4e-09 37.7 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN95369.1 - 7.4e-09 36.1 0.0 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN95369.1 - 9.4e-08 32.0 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN95369.1 - 2.7e-07 29.9 0.0 4.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDN95369.1 - 3.2e-05 23.3 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EDN95369.1 - 0.002 17.1 0.0 0.58 9.0 0.0 2.3 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family DUF3419 PF11899.3 EDN95369.1 - 0.0032 16.2 0.0 0.0049 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.4 EDN95369.1 - 0.0049 16.3 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EDN95369.1 - 0.044 14.6 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EDN95369.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) p450 PF00067.17 EDN95370.1 - 4.1e-52 177.2 0.0 5.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2b PF00587.20 EDN95371.1 - 4e-19 68.8 0.0 6.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDN95371.1 - 2.3e-12 46.8 5.3 1.5e-11 44.2 3.6 2.0 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ret_tiss PF10044.4 EDN95371.1 - 0.0029 18.1 0.2 0.0066 16.9 0.1 1.5 1 0 0 1 1 1 1 Retinal tissue protein HSBP1 PF06825.7 EDN95372.1 - 0.0006 19.3 0.0 0.71 9.4 0.0 4.4 3 1 0 3 3 3 1 Heat shock factor binding protein 1 Phage_rep_O PF04492.8 EDN95372.1 - 0.13 12.5 1.3 0.72 10.0 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage replication protein O Ish1 PF10281.4 EDN95373.1 - 9e-08 32.0 3.1 16 5.6 0.0 11.5 14 2 2 16 16 16 0 Putative stress-responsive nuclear envelope protein PMBR PF09373.5 EDN95373.1 - 0.00018 21.3 0.0 36 4.5 0.0 7.5 7 1 1 8 8 8 0 Pseudomurein-binding repeat Apolipoprotein PF01442.13 EDN95373.1 - 0.0093 15.5 10.4 0.028 13.9 0.1 3.7 4 0 0 4 4 4 2 Apolipoprotein A1/A4/E domain DUF3143 PF11341.3 EDN95373.1 - 0.021 14.7 1.5 88 3.0 0.0 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF3143) EnY2 PF10163.4 EDN95373.1 - 0.022 14.7 1.0 0.15 11.9 0.0 3.2 2 0 0 2 2 2 0 Transcription factor e(y)2 Tup_N PF08581.5 EDN95373.1 - 0.18 11.9 11.5 4.9 7.4 0.1 6.1 5 1 1 6 6 6 0 Tup N-terminal EF-hand_1 PF00036.27 EDN95373.1 - 0.29 10.5 3.0 10 5.7 0.0 4.6 3 0 0 3 3 3 0 EF hand FUSC PF04632.7 EDN95373.1 - 0.8 8.0 7.2 2.6 6.3 0.1 3.9 4 0 0 4 4 4 0 Fusaric acid resistance protein family IncA PF04156.9 EDN95373.1 - 0.85 9.1 16.5 2.7 7.5 0.1 4.3 4 0 0 4 4 4 0 IncA protein EF-hand_6 PF13405.1 EDN95373.1 - 1.1 9.2 8.7 28 4.9 0.0 6.2 7 0 0 7 7 7 0 EF-hand domain Ribosomal_L27e PF01777.13 EDN95374.1 - 5.4e-38 128.9 3.2 6.9e-38 128.6 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EDN95374.1 - 0.0065 16.1 1.4 0.011 15.4 0.2 2.0 2 0 0 2 2 2 1 KOW motif VacA2 PF03077.9 EDN95377.1 - 0.09 12.3 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Putative vacuolating cytotoxin TPR_14 PF13428.1 EDN95378.1 - 7.9e-10 38.4 1.0 1.2e-06 28.5 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN95378.1 - 3.4e-09 36.9 0.6 7.1e-09 35.8 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN95378.1 - 1.7e-08 33.9 0.0 4.5e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EDN95378.1 - 6.6e-08 31.8 0.0 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN95378.1 - 8.1e-08 31.5 0.0 0.0067 16.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN95378.1 - 1.6e-06 27.4 0.0 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN95378.1 - 8.3e-06 26.3 0.7 3.7e-05 24.2 0.0 2.3 2 1 0 3 3 2 1 Tetratricopeptide repeat ChAPs PF09295.5 EDN95378.1 - 3.7e-05 22.6 0.1 4.5e-05 22.4 0.1 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.1 EDN95378.1 - 4.4e-05 23.3 0.1 0.00082 19.3 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN95378.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 EDN95378.1 - 0.00029 20.8 0.1 0.026 14.6 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN95378.1 - 0.00058 19.7 0.0 0.0039 17.0 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN95378.1 - 0.0014 18.9 0.1 0.71 10.4 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN95378.1 - 0.0014 18.2 0.0 1.4 8.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDN95378.1 - 0.0044 16.1 0.1 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN95378.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Adaptin_N PF01602.15 EDN95379.1 - 2e-41 141.9 0.5 2.3e-33 115.3 0.1 2.5 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EDN95379.1 - 0.054 13.3 0.3 0.79 9.5 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SMAP PF15477.1 EDN95380.1 - 5e-17 61.9 3.7 5e-17 61.9 2.6 5.6 4 2 0 4 4 4 1 Small acidic protein family DUF1469 PF07332.6 EDN95381.1 - 0.031 13.9 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ribonuc_red_sm PF00268.16 EDN95381.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain zf-CCHC_3 PF13917.1 EDN95383.1 - 0.16 11.7 0.3 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Zinc knuckle Dicty_REP PF05086.7 EDN95383.1 - 4.2 5.0 8.4 7.1 4.2 5.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_A_type_inc PF04508.7 EDN95384.1 - 4.7 7.2 7.9 0.22 11.3 0.6 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat MOZ_SAS PF01853.13 EDN95385.1 - 2.3e-51 173.7 0.0 3.5e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Rpn3_C PF08375.6 EDN95386.1 - 1.9e-24 85.8 1.5 4.5e-24 84.6 1.0 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EDN95386.1 - 1.6e-19 70.1 0.6 4.7e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EDN95386.1 - 0.0075 16.1 0.2 0.028 14.3 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EDN95386.1 - 0.074 12.8 2.0 0.21 11.3 0.5 2.4 2 1 0 2 2 2 0 COP9 signalosome, subunit CSN8 TFIID_20kDa PF03847.8 EDN95387.1 - 1.9e-17 63.2 0.0 6.2e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EDN95387.1 - 0.034 14.1 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DASH_Spc34 PF08657.5 EDN95389.1 - 3.6e-61 207.0 11.3 3.7e-60 203.7 7.8 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 EDN95389.1 - 0.00045 19.8 7.4 0.00063 19.3 5.1 1.2 1 0 0 1 1 1 1 IncA protein DUF1978 PF09321.5 EDN95389.1 - 0.0047 16.3 9.4 0.0062 16.0 6.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) DUF4611 PF15387.1 EDN95389.1 - 0.019 15.1 1.5 0.034 14.2 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_13 PF13166.1 EDN95389.1 - 0.023 13.1 0.7 0.028 12.8 0.5 1.1 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 EDN95389.1 - 0.035 14.1 6.9 0.076 13.0 4.8 1.5 1 0 0 1 1 1 0 Up-regulated During Septation SlyX PF04102.7 EDN95389.1 - 0.064 13.6 4.9 4.4 7.7 0.1 2.9 2 0 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 EDN95389.1 - 0.091 12.5 8.8 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EDN95389.1 - 0.14 10.4 5.6 0.18 10.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDHD PF02862.12 EDN95389.1 - 0.48 10.1 2.9 0.66 9.7 2.0 1.2 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.14 EDN95389.1 - 0.83 7.4 5.0 1.1 7.0 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EDN95389.1 - 2.1 7.1 5.8 3 6.6 4.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2951 PF11166.3 EDN95389.1 - 2.2 8.2 7.5 0.34 10.7 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) KLRAQ PF10205.4 EDN95389.1 - 2.7 8.0 13.1 5 7.2 3.5 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 EDN95389.1 - 8.4 6.9 9.7 11 6.4 0.9 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HpcH_HpaI PF03328.9 EDN95392.1 - 7.2e-26 90.4 0.0 8.5e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Wound_ind PF08186.6 EDN95394.1 - 0.087 12.7 0.7 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 Wound-inducible basic protein family Spore_YhcN_YlaJ PF09580.5 EDN95394.1 - 0.12 12.4 0.7 0.12 12.4 0.5 1.0 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Glyco_transf_90 PF05686.7 EDN95395.1 - 2.6e-17 62.6 4.2 2.5e-11 42.8 0.1 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Microtub_assoc PF07989.6 EDN95396.1 - 1e-20 73.3 8.9 1e-20 73.3 6.2 8.4 6 1 3 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 EDN95396.1 - 3.3e-18 65.5 14.4 3.3e-18 65.5 10.0 12.1 13 2 0 13 13 13 4 Micro-tubular organiser Mto1 C-term Mto2-binding region SRPRB PF09439.5 EDN95398.1 - 0.089 12.0 0.1 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arginase PF00491.16 EDN95400.1 - 6.1e-77 258.6 0.2 7.1e-77 258.4 0.2 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 EDN95401.1 - 9.9e-07 28.6 16.4 2.3e-05 24.2 12.2 2.1 1 1 1 2 2 2 2 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EDN95401.1 - 0.29 10.7 24.3 0.087 12.4 9.7 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Voltage_CLC PF00654.15 EDN95401.1 - 1.1 8.1 13.2 1.5 7.8 9.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Tmemb_14 PF03647.8 EDN95401.1 - 8.7 6.8 10.0 2.4 8.6 2.8 2.1 2 0 0 2 2 2 0 Transmembrane proteins 14C DIOX_N PF14226.1 EDN95402.1 - 1.4e-29 102.9 0.0 2.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN95402.1 - 2.6e-21 75.7 0.0 4.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Topoisom_I_N PF02919.10 EDN95403.1 - 0.17 11.1 0.4 0.17 11.1 0.3 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Hemerythrin PF01814.18 EDN95404.1 - 0.016 15.3 0.2 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain RrnaAD PF00398.15 EDN95406.1 - 0.00016 20.7 0.0 0.017 14.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Nsp1_C PF05064.8 EDN95406.1 - 0.016 14.8 1.7 0.038 13.6 0.6 2.0 1 1 0 1 1 1 0 Nsp1-like C-terminal region JAB PF01398.16 EDN95407.1 - 4.8e-14 52.0 0.0 8.2e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EDN95407.1 - 4.8e-11 42.6 0.0 8.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EDN95407.1 - 3.3e-06 26.6 0.0 8.8e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CDO_I PF05995.7 EDN95408.1 - 2.5e-37 127.7 0.1 3.2e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I YwhD PF08741.5 EDN95409.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 YwhD family Virul_fac_BrkB PF03631.10 EDN95413.1 - 7e-05 22.3 4.9 9.9e-05 21.8 3.4 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF2721 PF11026.3 EDN95413.1 - 0.15 11.6 7.2 0.062 12.9 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) NfeD PF01957.13 EDN95413.1 - 8.6 6.4 8.2 1e+02 2.9 5.7 2.0 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding TIP_N PF12457.3 EDN95416.1 - 0.0081 16.2 2.4 0.01 15.8 0.1 2.3 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal Glypican PF01153.14 EDN95416.1 - 0.33 9.5 0.8 0.45 9.0 0.5 1.1 1 0 0 1 1 1 0 Glypican DHH PF01368.15 EDN95417.1 - 3.9e-07 29.8 0.0 6.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DHH family VSG_B PF13206.1 EDN95417.1 - 0.16 11.0 2.0 0.19 10.8 0.1 1.9 2 0 0 2 2 2 0 Trypanosomal VSG domain OTT_1508_deam PF14441.1 EDN95420.1 - 2.1e-10 40.5 0.3 2.1e-10 40.5 0.2 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase RasGAP PF00616.14 EDN95421.1 - 1.7e-54 184.5 0.0 2.9e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EDN95421.1 - 2.5e-30 105.0 3.6 6.4e-30 103.6 2.5 1.8 1 0 0 1 1 1 1 RasGAP C-terminus DnaJ PF00226.26 EDN95425.1 - 1.4e-08 34.2 0.6 5.3e-08 32.4 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain DUF2959 PF11172.3 EDN95425.1 - 0.059 13.1 0.2 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Glyco_hydro_18 PF00704.23 EDN95426.1 - 2.3e-98 329.8 0.6 2.6e-98 329.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNA_primase_S PF01896.14 EDN95430.1 - 9.8e-55 184.3 0.3 2.2e-54 183.2 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DEAD PF00270.24 EDN95431.1 - 5.2e-42 143.1 0.0 7.4e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN95431.1 - 1.5e-23 82.4 0.1 3.2e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Folliculin PF11704.3 EDN95433.1 - 8.8e-31 106.7 0.0 9.1e-30 103.4 0.0 2.6 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3331 PF11811.3 EDN95434.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) HET PF06985.6 EDN95435.1 - 1.1e-15 57.9 0.1 1.9e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.19 EDN95436.1 - 2.6e-59 200.8 0.1 1.1e-58 198.8 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase HET PF06985.6 EDN95437.1 - 3e-26 92.2 0.8 6.1e-26 91.2 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S41 PF03572.13 EDN95438.1 - 5.6e-05 22.6 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DUF4508 PF14969.1 EDN95439.1 - 0.015 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF4098 PF13345.1 EDN95440.1 - 0.00058 19.7 6.2 0.16 11.9 0.0 5.3 5 1 0 5 5 5 2 Domain of unknown function (DUF4098) DUF809 PF05663.6 EDN95444.1 - 0.033 14.0 0.1 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) PRP38 PF03371.10 EDN95445.1 - 5.1e-61 205.2 0.0 6.1e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PI3Ka PF00613.15 EDN95446.1 - 8.3e-59 197.8 0.4 1.4e-58 197.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EDN95446.1 - 4.4e-44 150.7 0.0 5.2e-43 147.1 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EDN95446.1 - 4.8e-30 104.2 0.0 8.3e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EDN95447.1 - 1.6e-34 117.8 0.0 3.3e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EDN95447.1 - 2.8e-16 59.0 0.3 6.9e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1691 PF07950.6 EDN95448.1 - 1e-44 150.9 8.0 6.3e-27 93.6 2.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF308 PF03729.8 EDN95448.1 - 0.069 13.1 5.9 0.17 11.8 4.1 1.8 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) zf-C2H2_jaz PF12171.3 EDN95449.1 - 1.7e-06 27.9 3.0 3.1e-06 27.1 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN95449.1 - 0.00081 19.5 0.5 0.0016 18.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDN95449.1 - 0.011 15.9 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 EDN95449.1 - 0.022 14.4 1.9 0.038 13.6 1.3 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 EDN95449.1 - 0.062 13.4 0.2 0.094 12.8 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EDN95449.1 - 0.064 13.6 0.4 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3360 PF11840.3 EDN95450.1 - 0.099 10.9 0.0 0.099 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) adh_short PF00106.20 EDN95451.1 - 0.009 15.9 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ISN1 PF06437.6 EDN95453.1 - 3e-176 586.1 0.0 9.4e-92 307.8 0.0 2.0 1 1 1 2 2 2 2 IMP-specific 5'-nucleotidase DUF1932 PF09130.6 EDN95453.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Metallophos PF00149.23 EDN95454.1 - 1e-07 31.5 1.8 1.9e-07 30.7 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidase PF01425.16 EDN95455.1 - 2e-68 231.2 0.0 3.4e-68 230.5 0.0 1.4 1 0 0 1 1 1 1 Amidase YlqD PF11068.3 EDN95455.1 - 0.059 13.3 2.1 0.1 12.6 1.5 1.3 1 0 0 1 1 1 0 YlqD protein Methyltransf_25 PF13649.1 EDN95456.1 - 3.1e-08 33.8 0.0 5.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN95456.1 - 1.9e-07 31.4 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN95456.1 - 2.7e-07 30.4 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN95456.1 - 9.2e-07 29.4 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN95456.1 - 8.3e-06 25.4 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN95456.1 - 9e-05 22.8 0.0 0.00035 21.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_7 PF03492.10 EDN95456.1 - 0.032 13.0 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ubie_methyltran PF01209.13 EDN95456.1 - 0.048 12.7 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EDN95456.1 - 0.084 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Herpes_LMP2 PF07415.6 EDN95457.1 - 0.0063 15.1 3.6 0.01 14.4 2.5 1.2 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein ADH_zinc_N PF00107.21 EDN95458.1 - 8.5e-17 60.9 0.1 1.9e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN95458.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CBFD_NFYB_HMF PF00808.18 EDN95460.1 - 2.8e-13 49.7 0.3 6.9e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN95460.1 - 0.0013 18.7 0.0 0.0075 16.3 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 YolD PF08863.5 EDN95460.1 - 0.22 11.3 3.2 1 9.2 0.4 2.6 2 0 0 2 2 2 0 YolD-like protein Bot1p PF12298.3 EDN95461.1 - 8.2e-55 185.3 1.2 1.2e-54 184.8 0.8 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein LZ_Tnp_IS481 PF13011.1 EDN95461.1 - 0.024 14.9 0.3 0.063 13.6 0.2 1.7 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Y_phosphatase3 PF13350.1 EDN95462.1 - 2.9e-50 170.7 0.0 3.8e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EDN95462.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EDN95462.1 - 5e-05 22.7 0.0 7.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EDN95462.1 - 0.0023 17.3 0.0 0.0048 16.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EDN95462.1 - 0.011 15.3 0.0 0.051 13.1 0.0 2.1 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EDN95462.1 - 0.18 10.5 0.0 0.58 8.8 0.0 1.7 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DUF2052 PF09747.4 EDN95463.1 - 1e-40 139.6 2.0 1.3e-40 139.2 1.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Repressor_Mnt PF11423.3 EDN95463.1 - 1.6 8.1 4.7 11 5.4 0.1 2.5 2 0 0 2 2 2 0 Regulatory protein Mnt Autophagy_N PF03986.8 EDN95464.1 - 6.4e-45 152.5 0.1 6.4e-45 152.5 0.1 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EDN95464.1 - 1.1e-21 76.7 0.9 2.3e-21 75.7 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EDN95464.1 - 1.5e-14 52.7 0.4 2.6e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Transket_pyr PF02779.19 EDN95465.1 - 1.3e-46 158.3 0.0 1.9e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN95465.1 - 2.1e-34 118.1 0.0 5.7e-34 116.7 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 EDN95465.1 - 0.03 13.0 0.0 0.059 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V UQ_con PF00179.21 EDN95467.1 - 1.5e-22 79.5 0.0 2.6e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GTSE1_N PF15259.1 EDN95467.1 - 0.00024 21.0 1.0 0.00052 19.9 0.7 1.6 1 0 0 1 1 1 1 G-2 and S-phase expressed 1 Tim54 PF11711.3 EDN95467.1 - 0.00073 18.2 1.4 0.00095 17.8 1.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RWD PF05773.17 EDN95467.1 - 0.0077 16.1 0.6 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 RWD domain zf-DHHC PF01529.15 EDN95470.1 - 6.9e-43 146.0 3.8 1.1e-42 145.4 2.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EDN95470.1 - 0.067 13.0 4.9 0.14 11.9 3.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 EDN95472.1 - 2.5e-08 33.7 18.8 0.037 14.3 0.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.2 EDN95472.1 - 7.9e-05 22.7 8.7 0.1 12.8 0.1 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDN95472.1 - 9.7e-05 22.4 15.5 0.092 13.1 0.4 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN95472.1 - 0.0001 22.0 13.5 0.023 14.5 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN95472.1 - 0.00015 21.7 9.5 0.054 13.6 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EDN95472.1 - 0.071 13.1 1.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 zinc-finger zf-H2C2_2 PF13465.1 EDN95472.1 - 0.079 13.2 15.9 2.8 8.4 1.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 EDN95472.1 - 0.14 12.2 8.0 16 5.6 0.4 3.9 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EDN95472.1 - 0.27 11.4 8.6 0.049 13.7 1.9 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hyd_65N_2 PF14498.1 EDN95473.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DSBA PF01323.15 EDN95474.1 - 1.7e-36 125.6 0.0 1.9e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EDN95474.1 - 0.00045 20.2 0.2 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 EDN95474.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.20 EDN95475.1 - 1e-21 77.6 0.3 1.5e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN95475.1 - 5.9e-11 42.5 0.1 8.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN95475.1 - 0.0006 19.3 0.1 0.00094 18.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDN95475.1 - 0.0017 18.0 0.8 0.0058 16.3 0.5 1.8 1 1 0 1 1 1 1 KR domain DUF1980 PF09323.5 EDN95478.1 - 0.022 14.4 0.8 0.042 13.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2636 PF11120.3 EDN95478.1 - 0.046 13.2 3.2 0.098 12.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Ceramidase PF05875.7 EDN95478.1 - 0.13 11.3 4.2 0.084 11.9 1.3 1.6 1 1 0 2 2 2 0 Ceramidase DUF373 PF04123.8 EDN95478.1 - 2.9 6.8 12.9 3.9 6.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cytochrom_B_C PF00032.12 EDN95478.1 - 9.6 6.4 12.9 3.2 8.0 1.5 3.2 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Lung_7-TM_R PF06814.8 EDN95481.1 - 6.5e-74 248.5 14.3 7.8e-74 248.2 9.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3753 PF12575.3 EDN95481.1 - 0.56 10.0 6.8 3.3 7.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF4131 PF13567.1 EDN95481.1 - 4.7 6.5 13.2 0.18 11.1 1.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2392 PF10288.4 EDN95482.1 - 4.5e-24 84.8 0.0 9.3e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EDN95482.1 - 0.097 12.1 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 PP-loop family Mito_carr PF00153.22 EDN95483.1 - 4e-41 138.6 7.5 4.2e-20 71.2 0.2 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein WD40 PF00400.27 EDN95484.1 - 1.8e-22 78.3 0.8 3.8e-10 39.2 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EDN95484.1 - 0.019 14.6 0.2 6.3 6.4 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Asp PF00026.18 EDN95488.1 - 6.6e-45 153.7 0.0 9.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EDN95488.1 - 4e-05 23.2 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EDN95488.1 - 0.0016 18.4 0.1 0.0042 17.0 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Zn_clus PF00172.13 EDN95489.1 - 4.5e-07 29.6 12.1 7.7e-07 28.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FBPase PF00316.15 EDN95491.1 - 1.2e-122 408.8 0.0 1.3e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase RRM_1 PF00076.17 EDN95492.1 - 1.4e-15 56.6 0.0 2.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN95492.1 - 2.7e-12 46.5 0.0 4.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN95492.1 - 5.5e-07 29.3 0.0 9.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN95492.1 - 0.052 13.4 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Methyltransf_23 PF13489.1 EDN95493.1 - 1.9e-18 66.7 0.0 2.6e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN95493.1 - 1.1e-15 57.8 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN95493.1 - 1.8e-15 56.8 0.0 2.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN95493.1 - 9.8e-13 48.6 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN95493.1 - 1.9e-12 47.4 0.0 3.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN95493.1 - 4.8e-08 33.0 0.0 3.1e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN95493.1 - 1.7e-06 28.3 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN95493.1 - 4.3e-06 26.0 0.0 6.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EDN95493.1 - 5.3e-05 22.4 0.0 6.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDN95493.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EDN95493.1 - 0.0051 15.9 0.0 0.0094 15.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DHBP_synthase PF00926.14 EDN95494.1 - 3.4e-72 241.7 0.0 2.4e-71 238.9 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-H2C2_2 PF13465.1 EDN95495.1 - 1.3e-15 56.7 19.6 2.2e-08 33.9 1.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDN95495.1 - 6.4e-15 54.4 16.8 2.1e-05 24.5 0.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN95495.1 - 2.2e-11 43.2 17.1 0.0014 18.8 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN95495.1 - 1.3e-05 25.1 2.3 1 9.5 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDN95495.1 - 0.00085 19.1 9.4 0.045 13.6 1.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EDN95495.1 - 0.0014 18.7 5.5 2.1 8.6 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type C1_4 PF07975.7 EDN95495.1 - 0.06 13.3 0.2 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 EDN95495.1 - 0.089 12.4 6.2 0.89 9.2 0.3 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 EDN95495.1 - 0.93 9.9 6.7 1.5 9.2 0.4 2.5 1 1 2 3 3 3 0 TRAF-type zinc finger Collagen_bind_2 PF12904.2 EDN95499.1 - 0.085 12.6 0.1 0.26 11.0 0.0 1.7 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase DUF3590 PF12148.3 EDN95501.1 - 0.087 12.4 5.2 0.068 12.7 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3590) Sec62 PF03839.11 EDN95501.1 - 0.58 9.5 4.9 0.7 9.2 3.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF728 PF05304.7 EDN95502.1 - 0.0074 16.4 0.1 0.0086 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF728) DNA_ligase_A_N PF04675.9 EDN95502.1 - 0.071 12.9 0.0 0.077 12.8 0.0 1.0 1 0 0 1 1 1 0 DNA ligase N terminus Peptidase_S10 PF00450.17 EDN95504.1 - 2.9e-78 263.8 2.0 5.5e-78 262.9 1.4 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase SNF2_N PF00176.18 EDN95505.1 - 3.6e-65 219.7 0.0 6.3e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN95505.1 - 4.5e-12 45.6 0.0 1.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EDN95505.1 - 1.4e-05 24.5 7.2 3.1e-05 23.5 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN95505.1 - 1.5e-05 24.9 5.9 3.1e-05 23.8 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN95505.1 - 0.0021 17.7 5.4 0.0048 16.6 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDN95505.1 - 0.004 16.8 3.3 0.012 15.2 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDN95505.1 - 0.016 15.0 6.5 0.038 13.8 4.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EDN95505.1 - 0.068 12.7 2.8 0.17 11.4 1.9 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Mgm101p PF06420.7 EDN95506.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Pex24p PF06398.6 EDN95508.1 - 0.0023 16.7 2.7 0.0027 16.5 1.9 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin O-antigen_lig PF13425.1 EDN95508.1 - 0.012 15.5 5.1 0.015 15.3 3.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YfhO PF09586.5 EDN95508.1 - 0.056 11.4 2.6 0.056 11.4 1.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2207 PF09972.4 EDN95508.1 - 0.077 11.5 6.7 0.074 11.6 4.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytochrome-c551 PF10643.4 EDN95508.1 - 0.11 11.7 2.7 0.12 11.6 1.8 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Wzy_C PF04932.10 EDN95508.1 - 0.14 11.9 8.4 0.15 11.8 5.8 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF1183 PF06682.7 EDN95508.1 - 0.67 9.5 3.6 1.3 8.5 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) CbiQ PF02361.11 EDN95508.1 - 1.5 8.2 10.1 1.7 8.1 7.0 1.2 1 0 0 1 1 1 0 Cobalt transport protein PIG-P PF08510.7 EDN95508.1 - 2.7 7.6 8.0 7.2 6.2 5.5 1.7 1 1 0 1 1 1 0 PIG-P DUF1700 PF08006.6 EDN95508.1 - 6.1 6.0 19.0 7.7 5.7 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) VirB3 PF05101.8 EDN95508.1 - 9.1 6.3 10.4 11 6.1 7.2 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF1295 PF06966.7 EDN95509.1 - 5.4e-37 127.3 0.3 3e-35 121.6 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EDN95509.1 - 0.00044 20.3 0.0 0.0019 18.3 0.0 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EDN95509.1 - 0.0083 16.3 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Aminotran_1_2 PF00155.16 EDN95510.1 - 2.4e-63 214.2 0.0 3.5e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDN95510.1 - 9.8e-05 21.6 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EDN95510.1 - 0.0052 15.1 0.0 0.011 14.0 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.23 EDN95512.1 - 9.1e-18 63.8 0.1 1.4e-17 63.1 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.23 EDN95513.1 - 2.9e-09 35.8 0.0 3.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN95513.1 - 8.4e-05 23.4 0.0 0.00012 22.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTCB-BRCT PF12738.2 EDN95514.1 - 3.2e-45 151.8 0.3 1.7e-20 72.6 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EDN95514.1 - 2.3e-38 130.1 0.1 6.8e-14 51.7 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.17 EDN95515.1 - 7.5e-20 71.4 0.0 3.7e-19 69.1 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDN95515.1 - 1.8e-09 37.5 0.1 0.00042 20.1 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain NmrA PF05368.8 EDN95516.1 - 8e-21 74.3 0.0 9.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN95516.1 - 7.7e-13 48.8 0.0 9.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN95516.1 - 0.0012 18.3 0.1 0.0072 15.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EDN95516.1 - 0.002 18.4 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EDN95516.1 - 0.11 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 EDN95517.1 - 3.2e-11 42.6 1.3 3.8e-10 39.0 0.9 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2576 PF10845.3 EDN95517.1 - 0.0084 15.2 0.5 0.016 14.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2576) Pyr_redox_3 PF13738.1 EDN95518.1 - 5.9e-23 81.9 0.0 1.5e-22 80.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN95518.1 - 1.7e-10 39.7 0.0 5.7e-09 34.7 0.0 2.4 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN95518.1 - 4.7e-10 38.9 0.0 2.5e-08 33.2 0.0 2.9 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN95518.1 - 1.2e-08 35.1 0.0 7e-08 32.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN95518.1 - 0.033 13.3 0.1 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EDN95518.1 - 0.06 13.3 0.1 0.28 11.2 0.1 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain RNase_H PF00075.19 EDN95519.1 - 4.9e-10 39.8 0.0 1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 RNase H Shisa PF13908.1 EDN95522.1 - 1.2 9.2 4.9 0.72 10.0 2.0 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator adh_short PF00106.20 EDN95523.1 - 1.1e-30 106.7 0.8 3.1e-28 98.7 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN95523.1 - 1.5e-23 83.8 0.3 1.9e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN95523.1 - 4.7e-10 39.4 0.3 2.2e-09 37.2 0.2 2.0 1 1 0 1 1 1 1 KR domain DUF4557 PF15101.1 EDN95523.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PALP PF00291.20 EDN95523.1 - 0.047 12.9 2.5 0.51 9.5 0.2 2.2 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.3 EDN95523.1 - 0.32 10.7 0.1 0.32 10.7 0.1 3.0 3 1 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_3 PF07859.8 EDN95524.1 - 8.5e-35 120.2 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN95524.1 - 2.8e-15 55.8 0.0 4.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EDN95524.1 - 6.3e-06 25.5 0.0 1.6e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN95524.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDN95524.1 - 0.00026 19.8 0.9 0.0013 17.5 0.6 1.8 1 1 0 1 1 1 1 Carboxylesterase family BAAT_C PF08840.6 EDN95524.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 EDN95524.1 - 0.049 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3328 PF11807.3 EDN95525.1 - 0.091 12.4 0.0 0.091 12.4 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) ketoacyl-synt PF00109.21 EDN95526.1 - 1.6e-69 234.2 0.0 3.2e-69 233.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EDN95526.1 - 1.5e-57 194.1 0.0 4.2e-57 192.7 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EDN95526.1 - 3.6e-52 177.6 0.1 6.4e-52 176.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EDN95526.1 - 7.3e-43 146.3 0.1 4.1e-42 143.9 0.0 2.5 2 0 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 EDN95526.1 - 2.2e-42 145.2 0.0 3.5e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EDN95526.1 - 2.8e-36 123.9 0.0 7.3e-36 122.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EDN95526.1 - 4.1e-18 65.6 0.0 1.1e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN95526.1 - 9.3e-13 48.0 0.0 2.6e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN95526.1 - 3.4e-11 43.1 0.0 8.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN95526.1 - 2.4e-09 37.7 0.0 2e-08 34.7 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN95526.1 - 2.5e-08 34.3 0.0 8.4e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EDN95526.1 - 2.1e-06 27.8 0.1 8.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 EDN95526.1 - 6.6e-05 22.6 0.1 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EDN95526.1 - 7.2e-05 22.0 0.0 0.0002 20.5 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.21 EDN95526.1 - 0.00024 20.6 0.2 0.00076 19.0 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EDN95526.1 - 0.011 14.7 0.1 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EDN95526.1 - 0.011 16.0 0.0 0.07 13.5 0.0 2.6 2 0 0 2 2 1 0 Methyltransferase domain ACP_syn_III_C PF08541.5 EDN95526.1 - 0.026 14.5 0.5 0.22 11.5 0.0 2.9 3 1 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Methyltransf_24 PF13578.1 EDN95526.1 - 0.037 14.8 0.0 0.2 12.5 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain DUF915 PF06028.6 EDN95526.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Bactofilin PF04519.8 EDN95527.1 - 3.3e-08 33.4 20.3 0.0043 17.0 1.8 4.0 1 1 3 4 4 4 4 Polymer-forming cytoskeletal DUF342 PF03961.8 EDN95527.1 - 2e-05 23.1 29.0 0.028 12.8 1.9 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF342) MinC_C PF03775.11 EDN95527.1 - 3.3e-05 23.4 17.5 0.29 10.7 0.3 5.4 1 1 5 6 6 6 5 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.6 EDN95527.1 - 0.015 15.2 0.1 2.9 7.8 0.0 3.6 2 2 0 2 2 2 0 Domain of Unknown Function (DUF748) Qn_am_d_aII PF14930.1 EDN95527.1 - 0.064 13.2 1.8 2.9 7.8 0.0 3.0 1 1 1 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II gp12-short_mid PF09089.5 EDN95527.1 - 0.094 12.6 4.0 2.9 7.9 0.7 2.9 2 1 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain DUF3494 PF11999.3 EDN95527.1 - 0.72 9.4 6.2 9.9 5.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3494) Phosphodiest PF01663.17 EDN95528.1 - 2.8e-85 286.8 0.8 3.8e-85 286.4 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN95528.1 - 0.00011 21.5 0.4 0.054 12.6 0.3 2.5 1 1 0 1 1 1 1 Sulfatase WD40 PF00400.27 EDN95531.1 - 1.6e-33 113.3 4.5 1.5e-09 37.3 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF2173 PF09941.4 EDN95531.1 - 0.049 13.5 0.0 9.7 6.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2173) Cupin_2 PF07883.6 EDN95534.1 - 5.3e-12 45.0 0.4 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EDN95534.1 - 4.9e-05 22.6 0.1 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) EutQ PF06249.7 EDN95534.1 - 0.00038 20.0 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 EDN95534.1 - 0.0029 17.2 0.0 0.2 11.2 0.0 2.5 2 1 0 2 2 2 1 Cupin CENP-C_C PF11699.3 EDN95534.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Mif2/CENP-C like Prominin PF05478.6 EDN95535.1 - 0.2 9.1 0.2 0.26 8.7 0.1 1.1 1 0 0 1 1 1 0 Prominin Rifin_STEVOR PF02009.11 EDN95535.1 - 0.57 9.7 3.8 0.96 9.0 2.7 1.5 1 0 0 1 1 1 0 Rifin/stevor family LPP PF04728.8 EDN95535.1 - 0.6 9.9 4.7 5 6.9 1.2 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Acyl-CoA_dh_N PF02771.11 EDN95536.1 - 4.1e-17 62.7 0.1 5.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PHD PF00628.24 EDN95537.1 - 6.3e-10 38.5 1.9 1.4e-09 37.4 1.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN95537.1 - 0.023 13.9 2.9 0.041 13.2 2.0 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EDN95537.1 - 1.3 8.8 5.4 3.3 7.5 0.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4596 PF15363.1 EDN95537.1 - 3 7.8 5.8 5.4 7.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Trypan_PARP PF05887.6 EDN95538.1 - 0.35 10.6 5.8 1.3 8.8 4.0 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) 2OG-FeII_Oxy_3 PF13640.1 EDN95539.1 - 0.0013 19.2 0.0 0.0029 18.0 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CPSase_L_D2 PF02786.12 EDN95540.1 - 1.5e-72 243.2 0.0 2.2e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EDN95540.1 - 7.7e-37 125.5 0.0 1.8e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EDN95540.1 - 3.7e-18 64.9 1.0 4.8e-17 61.3 0.9 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme CPSase_L_chain PF00289.17 EDN95540.1 - 4.2e-18 65.4 0.0 9.4e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN95540.1 - 6.2e-17 61.9 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN95540.1 - 8.6e-11 41.1 0.0 2.3e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN95540.1 - 8.4e-09 35.1 0.0 1.9e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EDN95540.1 - 4.5e-07 29.4 0.1 0.014 15.0 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EDN95540.1 - 1.4e-06 27.7 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EDN95540.1 - 0.00015 21.2 0.7 0.34 10.1 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 EDN95540.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EDN95540.1 - 0.0028 17.1 0.0 0.0074 15.7 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EDN95540.1 - 0.0029 17.9 0.1 2.7 8.3 0.0 3.1 3 0 0 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 EDN95540.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 EDN95540.1 - 0.028 14.1 0.1 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) YjeF_N PF03853.10 EDN95541.1 - 4.8e-35 120.6 0.0 6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EDN95542.1 - 3.5e-23 81.1 0.0 5.6e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 EDN95543.1 - 3.1e-93 312.4 18.3 4e-93 312.1 12.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EDN95543.1 - 1.4e-05 24.1 20.1 1.4e-05 24.1 14.0 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family GlnD_UR_UTase PF08335.6 EDN95544.1 - 0.0046 16.8 0.3 0.0069 16.2 0.2 1.2 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase SH3_1 PF00018.23 EDN95546.1 - 1.5e-08 33.8 0.1 2.6e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN95546.1 - 2.4e-06 27.0 0.0 4.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN95546.1 - 6.1e-06 25.6 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dispanin PF04505.7 EDN95546.1 - 0.026 14.0 0.5 0.026 14.0 0.3 2.5 3 1 0 3 3 3 0 Interferon-induced transmembrane protein 7TMR-DISM_7TM PF07695.6 EDN95546.1 - 0.1 12.2 9.9 0.13 11.8 6.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3623 PF12291.3 EDN95546.1 - 0.62 8.9 5.3 0.98 8.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) IBN_N PF03810.14 EDN95547.1 - 2.1e-10 40.3 6.1 5.4e-10 39.0 0.0 3.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain Cse1 PF08506.5 EDN95547.1 - 1.2e-05 24.0 0.4 3.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 EDN95547.1 - 0.0001 22.2 4.4 0.027 14.3 0.0 4.7 5 0 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 EDN95547.1 - 0.00022 21.4 1.9 0.39 11.0 0.0 3.5 3 1 0 3 3 3 2 HEAT repeats DUF2435 PF10363.4 EDN95547.1 - 0.017 15.0 0.3 0.058 13.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EDN95547.1 - 0.033 14.5 3.5 1.5 9.2 0.1 3.9 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region zf-C3HC4_3 PF13920.1 EDN95549.1 - 1.1e-08 34.6 4.4 1.8e-08 33.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN95549.1 - 2.4e-08 33.8 9.6 4.2e-08 33.0 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EDN95549.1 - 6e-07 28.9 2.3 1.2e-06 28.0 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 EDN95549.1 - 8.6e-07 28.5 9.1 1.6e-06 27.6 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN95549.1 - 9.4e-07 28.4 7.6 1.7e-06 27.6 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN95549.1 - 1.6e-05 24.6 6.0 2.6e-05 23.9 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDN95549.1 - 0.0035 17.1 7.7 0.0075 16.1 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDN95549.1 - 0.012 15.3 3.2 0.029 14.0 2.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EDN95549.1 - 0.15 11.5 1.3 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 EDN95549.1 - 0.91 9.9 9.8 0.12 12.7 3.3 2.2 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT TT_ORF1 PF02956.9 EDN95550.1 - 9.3 4.5 12.0 8.7 4.6 8.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 Circo_capsid PF02443.10 EDN95550.1 - 9.6 5.4 11.1 10 5.3 7.7 1.0 1 0 0 1 1 1 0 Circovirus capsid protein Mcp5_PH PF12814.2 EDN95551.1 - 2.4e-43 146.9 0.7 5e-43 145.9 0.0 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology p450 PF00067.17 EDN95552.1 - 6.7e-59 199.6 0.0 8.5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.17 EDN95553.1 - 1.6 7.6 2.4 2.1 7.2 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EDN95553.1 - 1.9 6.0 4.1 2.4 5.7 2.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EDN95553.1 - 5.3 4.9 14.7 7.8 4.3 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TIM PF00121.13 EDN95555.1 - 1.3e-86 289.7 0.1 1.4e-86 289.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.11 EDN95556.1 - 7e-16 57.7 0.0 9.6e-16 57.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EDN95557.1 - 3.4e-32 110.6 3.8 1.5e-31 108.5 3.1 1.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EDN95557.1 - 4.2e-11 42.3 0.2 2.3e-10 39.9 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN95557.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN95557.1 - 0.026 14.3 1.2 0.071 12.9 0.2 2.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EDN95558.1 - 1.8e-18 66.2 0.0 2.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3722 PF12519.3 EDN95559.1 - 2.1e-96 322.1 0.0 2.6e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EDN95559.1 - 1.1e-06 28.1 0.0 0.086 12.1 0.0 3.4 3 1 0 4 4 4 2 Eukaryotic porin Zip PF02535.17 EDN95560.1 - 8.8e-56 189.2 7.2 2.5e-55 187.7 5.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_transf_15 PF01793.11 EDN95563.1 - 6.1e-134 446.1 0.4 7.7e-134 445.7 0.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.1 EDN95564.1 - 1.6e-21 77.1 15.2 1.9e-21 76.8 10.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Daxx PF03344.10 EDN95564.1 - 0.71 8.2 12.6 0.93 7.9 8.8 1.1 1 0 0 1 1 1 0 Daxx Family PRP21_like_P PF12230.3 EDN95564.1 - 2.7 7.4 11.7 4.9 6.5 2.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein YEATS PF03366.11 EDN95565.1 - 6.2e-23 80.3 0.0 1.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family IL3 PF02059.10 EDN95565.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Interleukin-3 REV PF00424.13 EDN95565.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ran_BP1 PF00638.13 EDN95566.1 - 9e-49 164.5 1.5 1.6e-48 163.8 1.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EDN95566.1 - 0.00087 18.9 0.5 0.0054 16.4 0.3 2.0 1 1 0 1 1 1 1 WH1 domain Acyl-CoA_dh_2 PF08028.6 EDN95566.1 - 0.016 15.4 0.3 0.039 14.2 0.2 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain FHIPEP PF00771.15 EDN95566.1 - 0.12 10.6 1.3 0.17 10.1 0.9 1.3 1 1 0 1 1 1 0 FHIPEP family CDC27 PF09507.5 EDN95566.1 - 0.26 10.4 17.3 0.32 10.1 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF904 PF06005.7 EDN95568.1 - 0.24 11.6 1.7 0.29 11.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) IGF2_C PF08365.6 EDN95569.1 - 0.0045 16.7 1.4 0.0053 16.4 1.0 1.1 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Fungal_trans_2 PF11951.3 EDN95572.1 - 1.2e-49 168.9 0.2 1.7e-49 168.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain dCMP_cyt_deam_1 PF00383.17 EDN95575.1 - 1.6e-19 69.4 0.0 2.8e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EDN95575.1 - 0.00024 20.9 0.1 0.0048 16.7 0.1 2.4 1 1 0 1 1 1 1 Bd3614-like deaminase YwqJ-deaminase PF14431.1 EDN95575.1 - 0.0067 16.2 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 YwqJ-like deaminase NADH-u_ox-rdase PF10785.4 EDN95576.1 - 4.2e-34 116.6 0.2 6.5e-34 116.0 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EDN95576.1 - 9.8e-34 114.9 0.3 1.4e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 EDN95577.1 - 2.7e-31 107.0 0.2 5.7e-31 105.9 0.2 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.7 EDN95578.1 - 3.7e-56 189.2 0.1 7.2e-56 188.2 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDN95578.1 - 7.4e-11 41.8 0.2 4.3e-10 39.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN95578.1 - 8.3e-07 28.7 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EDN95578.1 - 0.017 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain 2OG-FeII_Oxy_2 PF13532.1 EDN95579.1 - 1.2e-18 67.7 0.5 2.5e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ldh_1_C PF02866.13 EDN95580.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain AMP-binding PF00501.23 EDN95581.1 - 3.7e-58 196.8 0.0 7.7e-33 113.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN95581.1 - 1.9e-12 47.9 0.1 3.6e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WAC_Acf1_DNA_bd PF10537.4 EDN95581.1 - 0.011 15.8 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal WD40 PF00400.27 EDN95582.1 - 1.8e-33 113.1 0.8 1.6e-07 30.9 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDN95582.1 - 0.003 17.0 0.0 0.26 10.8 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EDN95582.1 - 0.058 13.0 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SnoaL PF07366.7 EDN95584.1 - 0.00028 20.4 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EDN95584.1 - 0.024 15.0 0.1 0.049 14.0 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain DDE_1 PF03184.14 EDN95585.1 - 2.7e-49 167.2 0.0 4.7e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95585.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN95585.1 - 3.9e-08 33.1 0.0 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95585.1 - 4.2e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN95585.1 - 0.012 15.4 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Fungal_trans PF04082.13 EDN95586.1 - 2.1e-24 85.8 0.2 3.2e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN95586.1 - 1.8e-08 34.1 10.0 3.8e-08 33.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STAG PF08514.6 EDN95587.1 - 9e-29 99.5 0.5 1.5e-27 95.6 0.0 3.0 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 EDN95587.1 - 0.0015 18.4 0.3 19 5.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EDN95587.1 - 0.014 15.2 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EDN95587.1 - 0.02 14.8 2.4 1.9 8.5 1.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cut8_N PF14482.1 EDN95587.1 - 0.43 10.6 4.5 9.1 6.3 0.9 3.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain UreD PF01774.12 EDN95588.1 - 2.8e-55 187.0 0.0 3.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF3129 PF11327.3 EDN95590.1 - 1.4e-59 200.9 12.0 2.1e-59 200.4 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) APH PF01636.18 EDN95591.1 - 2.1e-06 27.6 0.0 1.7e-05 24.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN95591.1 - 3.8e-05 23.3 0.0 5.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EDN95591.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3787 PF12655.2 EDN95591.1 - 0.32 10.7 2.4 0.45 10.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3787) tRNA_anti-codon PF01336.20 EDN95593.1 - 0.022 14.6 0.1 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Arm PF00514.18 EDN95594.1 - 4.8e-95 308.5 13.2 2.7e-13 49.1 0.1 8.5 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDN95594.1 - 1.9e-27 95.3 1.1 2.4e-09 37.3 0.0 5.6 1 1 6 7 7 7 7 HEAT repeats IBB PF01749.15 EDN95594.1 - 1e-21 76.8 0.7 1.8e-21 76.0 0.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EDN95594.1 - 2.3e-20 72.4 10.8 1.8e-08 34.5 0.0 6.2 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EDN95594.1 - 3.1e-19 67.2 1.0 2.3e-05 24.1 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 EDN95594.1 - 6.4e-10 38.5 0.0 0.00025 20.2 0.0 3.8 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.3 EDN95594.1 - 0.0003 20.6 0.0 0.98 9.3 0.0 4.4 3 1 2 5 5 5 1 V-ATPase subunit H Adaptin_N PF01602.15 EDN95594.1 - 0.00037 18.9 0.0 0.029 12.6 0.0 3.1 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.11 EDN95594.1 - 0.0045 17.3 2.9 1.8 9.2 0.0 4.7 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EDN95594.1 - 0.018 13.3 0.0 0.62 8.2 0.0 2.6 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Abhydrolase_3 PF07859.8 EDN95595.1 - 1e-35 123.2 0.1 4.4e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EDN95595.1 - 1.7e-07 30.3 0.8 3.7e-07 29.2 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EDN95595.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_2 PF00152.15 EDN95597.1 - 8.9e-70 235.0 0.5 2.7e-37 128.2 0.0 2.9 2 1 1 3 3 3 2 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EDN95597.1 - 1.3e-12 47.2 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EDN95597.1 - 0.00078 19.2 0.1 0.002 17.9 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ndc1_Nup PF09531.5 EDN95597.1 - 2.6 6.3 2.9 4.3 5.6 2.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAF-1_p150 PF11600.3 EDN95597.1 - 6.2 6.1 16.5 0.33 10.3 6.8 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ADH_zinc_N_2 PF13602.1 EDN95598.1 - 1e-24 87.8 0.5 1.7e-24 87.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN95598.1 - 1.5e-16 60.0 1.6 2.4e-16 59.4 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cas_VVA1548 PF09652.5 EDN95598.1 - 0.16 11.9 0.7 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) Ank_2 PF12796.2 EDN95600.1 - 1.6e-45 153.3 1.7 5.5e-22 77.9 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN95600.1 - 8.2e-41 135.8 2.4 4.6e-08 32.4 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EDN95600.1 - 1.8e-36 123.8 5.9 5e-11 42.7 0.0 6.3 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN95600.1 - 1.8e-31 107.4 0.5 1.4e-09 37.8 0.0 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN95600.1 - 6.1e-27 90.9 1.6 2.2e-05 24.2 0.0 7.2 6 1 1 7 7 7 4 Ankyrin repeat F-box PF00646.28 EDN95601.1 - 2e-05 24.0 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN95601.1 - 0.0012 18.5 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like NUDIX PF00293.23 EDN95603.1 - 1.4e-12 47.3 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-CCHC_5 PF14787.1 EDN95604.1 - 0.011 15.2 0.2 0.011 15.2 0.1 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3315 PF11776.3 EDN95604.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) DUF3835 PF12927.2 EDN95605.1 - 0.15 13.0 1.7 0.22 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) SET PF00856.23 EDN95606.1 - 5.9e-15 55.9 0.0 1.4e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.1 EDN95606.1 - 0.036 13.9 0.1 0.2 11.5 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Cyanate_lyase PF02560.9 EDN95607.1 - 2.1e-31 107.2 0.0 3e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 EDN95607.1 - 0.00012 21.4 0.1 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_31 PF13560.1 EDN95607.1 - 0.028 14.6 0.1 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 EDN95607.1 - 0.029 14.5 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Neuroparsin PF07327.6 EDN95608.1 - 0.12 12.6 3.6 0.13 12.5 2.5 1.2 1 0 0 1 1 1 0 Neuroparsin zf-C2H2_4 PF13894.1 EDN95609.1 - 0.014 15.7 0.6 2.4 8.6 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC PF01530.13 EDN95609.1 - 0.13 12.0 2.8 0.52 10.0 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2HC type Zn_clus PF00172.13 EDN95613.1 - 3e-07 30.2 11.0 3e-07 30.2 7.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN95613.1 - 0.00018 20.2 0.0 0.00032 19.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliJ PF02050.11 EDN95613.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Ank_2 PF12796.2 EDN95614.1 - 1.8e-39 133.9 1.5 1.2e-11 44.8 0.3 5.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EDN95614.1 - 2.8e-30 102.5 4.5 1e-05 25.0 0.1 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EDN95614.1 - 3.8e-30 103.7 4.5 4.9e-05 23.7 0.0 7.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN95614.1 - 3.9e-27 91.5 3.0 3.2e-05 23.7 0.0 8.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EDN95614.1 - 2.1e-22 78.6 4.7 1.4e-07 31.5 0.0 6.5 5 2 2 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.2 EDN95614.1 - 0.026 14.2 0.1 0.059 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like Recep_L_domain PF01030.19 EDN95615.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Receptor L domain Sulfatase PF00884.18 EDN95620.1 - 6e-54 183.3 0.0 7.6e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EDN95620.1 - 1.4e-23 82.4 0.3 3.4e-23 81.2 0.1 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EDN95620.1 - 3.2e-10 39.8 0.1 4.6e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EDN95620.1 - 0.081 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Tox-HDC PF15656.1 EDN95620.1 - 0.099 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Glyco_hydro_16 PF00722.16 EDN95621.1 - 2.4e-09 36.7 0.4 3.4e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EDN95621.1 - 0.012 13.7 0.2 0.017 13.2 0.1 1.5 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) RseA_N PF03872.8 EDN95621.1 - 0.1 12.9 0.2 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain DUF2939 PF11159.3 EDN95623.1 - 1.8 8.8 6.0 0.27 11.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Rhomboid PF01694.17 EDN95624.1 - 2.7e-34 118.2 11.4 5.3e-34 117.3 7.9 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1129 PF06570.6 EDN95624.1 - 3 7.0 5.6 3.3 6.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DNA_pol_B PF00136.16 EDN95626.1 - 9.1e-144 479.7 4.3 1.5e-143 478.9 3.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDN95626.1 - 3.3e-82 275.9 1.3 6.8e-82 274.9 0.9 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDN95626.1 - 3.7e-21 74.8 8.6 3.7e-21 74.8 6.0 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EDN95626.1 - 0.00011 22.0 0.6 0.0006 19.6 0.4 2.3 1 1 0 1 1 1 1 RNase_H superfamily DUF2614 PF11023.3 EDN95626.1 - 0.079 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) DUF3435 PF11917.3 EDN95627.1 - 4.2e-68 229.9 0.0 6.6e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) AAA_10 PF12846.2 EDN95627.1 - 0.077 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain zf-RanBP PF00641.13 EDN95628.1 - 6.4 5.9 11.5 9.7 5.3 0.2 3.6 3 1 0 3 3 3 0 Zn-finger in Ran binding protein and others RVT_1 PF00078.22 EDN95629.1 - 1.5e-17 63.6 0.0 2.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN95629.1 - 0.037 13.6 0.4 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN95630.1 - 9.8e-22 77.3 0.0 5.8e-21 74.8 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN95630.1 - 1.4e-12 48.1 0.0 3.8e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 EDN95630.1 - 0.0024 17.6 0.0 0.007 16.1 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like TetR PF13972.1 EDN95630.1 - 0.055 12.9 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial transcriptional repressor WD40 PF00400.27 EDN95631.1 - 1.5e-14 53.1 0.4 2.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EDN95631.1 - 0.038 12.1 0.1 0.042 11.9 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HET PF06985.6 EDN95632.1 - 1.2e-23 83.8 9.0 9.1e-22 77.7 6.2 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EDN95632.1 - 3.5e-12 45.7 0.0 5.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EDN95632.1 - 7.9e-08 32.5 0.0 3.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN95632.1 - 1.2e-07 31.8 0.0 5.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDN95632.1 - 1.8e-06 27.6 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arabinose_bd PF12625.2 EDN95632.1 - 0.0084 15.9 1.3 5.3 6.8 0.0 3.8 3 1 2 5 5 5 1 Arabinose-binding domain of AraC transcription regulator, N-term DUF2075 PF09848.4 EDN95632.1 - 0.059 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EDN95632.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EDN95632.1 - 0.1 12.5 0.0 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EDN95632.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein KaiC PF06745.8 EDN95633.1 - 0.041 12.9 0.2 0.066 12.3 0.2 1.2 1 0 0 1 1 1 0 KaiC RXT2_N PF08595.6 EDN95637.1 - 0.0071 16.1 0.2 0.0093 15.7 0.1 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF334 PF03904.8 EDN95640.1 - 2.7 7.2 6.0 2.9 7.1 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) HSP70 PF00012.15 EDN95641.1 - 0.011 13.6 0.4 0.027 12.4 0.0 1.8 3 0 0 3 3 3 0 Hsp70 protein RIO1 PF01163.17 EDN95646.1 - 0.0018 17.6 0.0 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EDN95646.1 - 0.0093 15.7 0.1 0.23 11.1 0.1 2.4 1 1 2 3 3 3 1 Phosphotransferase enzyme family Rifin_STEVOR PF02009.11 EDN95649.1 - 0.017 14.7 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 EDN95649.1 - 0.045 13.0 0.8 0.09 12.1 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain P12 PF12669.2 EDN95649.1 - 0.048 13.8 0.5 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family NfeD PF01957.13 EDN95649.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF1180 PF06679.7 EDN95649.1 - 2 8.2 12.1 0.11 12.3 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MKT1_C PF12246.3 EDN95652.1 - 3.3e-42 144.1 0.1 1.7e-28 99.3 0.0 2.4 1 1 1 2 2 2 2 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EDN95652.1 - 1.3e-25 89.5 0.0 3.6e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EDN95652.1 - 0.00058 20.0 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDN95652.1 - 0.0016 18.4 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region TPR_2 PF07719.12 EDN95652.1 - 0.056 13.3 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.15 EDN95653.1 - 1.8e-14 53.8 0.0 3.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN95653.1 - 1.9e-14 54.1 0.0 2.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TruB_N PF01509.13 EDN95654.1 - 9e-44 149.2 0.0 5e-43 146.8 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Glyco_hyd_65N_2 PF14498.1 EDN95656.1 - 1.2e-50 172.4 0.0 1.9e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 EDN95656.1 - 0.0015 17.2 0.0 0.0026 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain RVT_1 PF00078.22 EDN95657.1 - 1e-30 106.6 1.5 1.1e-30 106.6 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN95657.1 - 1.9e-21 75.8 3.4 2e-21 75.8 1.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN95657.1 - 6.9e-05 22.8 0.9 0.00011 22.2 0.6 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDN95657.1 - 0.1 12.2 0.2 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.19 EDN95658.1 - 1.8e-15 57.4 0.0 3.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 RNase H CrtC PF07143.6 EDN95660.1 - 1e-18 67.7 2.3 1.5e-18 67.2 1.6 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) FAD_binding_3 PF01494.14 EDN95661.1 - 8.6e-26 90.8 3.6 2.1e-12 46.7 0.2 2.4 1 1 1 2 2 2 2 FAD binding domain bZIP_1 PF00170.16 EDN95661.1 - 1.9e-08 34.1 8.3 4.3e-08 32.9 5.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor DAO PF01266.19 EDN95661.1 - 1.2e-06 27.7 1.5 1.6e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN95661.1 - 1.7e-06 27.9 0.1 6e-06 26.1 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN95661.1 - 1.5e-05 24.1 0.6 6.3e-05 22.1 0.1 2.2 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 EDN95661.1 - 3.1e-05 24.1 0.0 8.4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN95661.1 - 0.00015 20.5 0.0 0.00025 19.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 EDN95661.1 - 0.00068 19.9 0.7 0.0016 18.8 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN95661.1 - 0.0015 18.4 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EDN95661.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.19 EDN95661.1 - 0.003 16.4 1.0 0.0051 15.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EDN95661.1 - 0.0053 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EDN95661.1 - 0.0084 14.6 0.2 0.014 13.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.1 EDN95661.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EDN95661.1 - 0.011 15.0 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IncA PF04156.9 EDN95661.1 - 0.015 14.8 2.5 0.033 13.8 1.7 1.5 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EDN95661.1 - 0.016 14.9 12.8 0.036 13.8 8.7 1.7 1 1 0 1 1 1 0 Basic region leucine zipper AlaDh_PNT_C PF01262.16 EDN95661.1 - 0.018 14.6 0.3 0.047 13.2 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SlyX PF04102.7 EDN95661.1 - 0.021 15.2 1.1 0.063 13.6 0.8 1.9 1 0 0 1 1 1 0 SlyX Shikimate_DH PF01488.15 EDN95661.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDN95661.1 - 0.04 13.5 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WEMBL PF05701.6 EDN95661.1 - 0.059 11.8 2.1 0.31 9.4 0.8 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Amino_oxidase PF01593.19 EDN95661.1 - 0.063 12.3 0.1 0.063 12.3 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase XdhC_C PF13478.1 EDN95661.1 - 0.07 13.4 0.4 0.32 11.2 0.0 2.2 3 0 0 3 3 2 0 XdhC Rossmann domain DUF1664 PF07889.7 EDN95661.1 - 0.072 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ThiF PF00899.16 EDN95661.1 - 0.079 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 ThiF family Prefoldin_2 PF01920.15 EDN95661.1 - 0.16 11.7 2.1 0.22 11.2 0.6 1.9 2 0 0 2 2 1 0 Prefoldin subunit bZIP_Maf PF03131.12 EDN95661.1 - 0.55 10.5 10.2 0.25 11.6 5.0 2.0 2 0 0 2 2 1 0 bZIP Maf transcription factor HhH-GPD PF00730.20 EDN95662.1 - 0.0002 21.5 0.1 0.00071 19.8 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDN95662.1 - 0.0098 15.5 0.2 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Metallophos_2 PF12850.2 EDN95662.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EspF PF04806.7 EDN95662.1 - 0.091 12.9 0.4 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 EspF protein repeat Methyltransf_20 PF12147.3 EDN95663.1 - 0.091 11.6 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Putative methyltransferase IMS PF00817.15 EDN95664.1 - 1.5e-39 135.1 0.0 2.4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family ADH_N PF08240.7 EDN95665.1 - 1.8e-11 43.7 0.1 3.1e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN95665.1 - 0.0034 16.9 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Coagulin PF02035.10 EDN95668.1 - 0.14 11.8 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Coagulin zf-MYND PF01753.13 EDN95669.1 - 2.6e-07 30.3 20.2 7.4e-07 28.9 14.0 1.8 1 0 0 1 1 1 1 MYND finger HTH_psq PF05225.11 EDN95671.1 - 2e-10 40.0 0.2 2.3e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EDN95671.1 - 0.0067 16.3 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_23 PF13384.1 EDN95671.1 - 0.059 13.0 0.1 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 EDN95671.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EDN95672.1 - 2.5e-23 82.3 2.9 4e-23 81.6 0.7 1.8 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 EDN95674.1 - 2.5e-27 95.5 0.0 4.8e-27 94.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GON PF08685.6 EDN95674.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 GON domain Ebp2 PF05890.7 EDN95677.1 - 1.6e-95 319.5 16.8 1.6e-95 319.5 11.7 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 BUD22 PF09073.5 EDN95677.1 - 0.37 9.8 47.6 0.01 14.9 20.3 2.4 2 0 0 2 2 2 0 BUD22 Cation_efflux PF01545.16 EDN95679.1 - 8e-33 113.7 9.5 1e-32 113.3 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family PLAC8 PF04749.12 EDN95679.1 - 0.15 12.6 1.7 0.26 11.8 0.1 2.1 2 0 0 2 2 2 0 PLAC8 family Dynamin_N PF00350.18 EDN95680.1 - 1.7e-43 148.3 0.0 3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDN95680.1 - 3e-13 49.2 0.3 8.1e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EDN95680.1 - 0.0012 18.8 0.0 0.02 14.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EDN95680.1 - 0.0042 17.5 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRI PF08236.6 EDN95680.1 - 0.07 13.0 0.2 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_16 PF13191.1 EDN95680.1 - 0.092 12.7 1.8 0.68 9.8 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 EDN95680.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 EDN95681.1 - 5.1e-14 51.6 0.0 5.7e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDN95681.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EDN95681.1 - 0.00047 18.9 0.0 0.0008 18.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA_23 PF13476.1 EDN95682.1 - 0.15 12.4 11.0 0.2 11.9 7.6 1.1 1 0 0 1 1 1 0 AAA domain AA_permease PF00324.16 EDN95684.1 - 1.5e-118 396.1 45.4 1.8e-118 395.9 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN95684.1 - 1.1e-35 122.9 56.0 1.9e-35 122.2 38.2 1.6 1 1 0 1 1 1 1 Amino acid permease PQ-loop PF04193.9 EDN95685.1 - 1e-34 117.8 12.1 3.1e-18 65.0 2.8 3.0 3 0 0 3 3 3 2 PQ loop repeat TctB PF07331.6 EDN95685.1 - 0.0036 16.9 0.4 0.009 15.6 0.2 1.8 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family GtrA PF04138.9 EDN95685.1 - 7 6.6 10.8 1.5 8.8 0.1 2.9 2 1 0 3 3 3 0 GtrA-like protein PhzC-PhzF PF02567.11 EDN95686.1 - 0.055 12.6 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DUF2417 PF10329.4 EDN95688.1 - 0.018 14.4 0.3 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Pex24p PF06398.6 EDN95688.1 - 0.68 8.6 5.9 2.8 6.6 4.1 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin TP53IP5 PF15331.1 EDN95689.1 - 0.026 14.4 0.9 0.038 13.9 0.6 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Zip PF02535.17 EDN95689.1 - 0.031 13.3 0.2 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2365 PF10157.4 EDN95689.1 - 0.3 10.9 0.1 0.3 10.9 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF3328 PF11807.3 EDN95689.1 - 2 8.0 6.1 0.2 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Zn_clus PF00172.13 EDN95690.1 - 0.00028 20.7 11.5 0.0005 19.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EDN95690.1 - 0.036 13.2 7.2 0.048 12.9 0.0 3.5 3 0 0 3 3 3 0 Histone chaperone domain CHZ RB_B PF01857.15 EDN95692.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.18 EDN95693.1 - 5.4e-43 145.5 0.0 1.1e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDN95693.1 - 5.6e-33 113.3 0.2 1.5e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Mito_carr PF00153.22 EDN95695.1 - 2.1e-74 245.3 0.2 1.9e-25 88.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EDN95695.1 - 2.5e-15 54.9 4.8 3.7e-07 29.4 0.1 5.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EDN95695.1 - 4.1e-15 53.8 3.8 3.1e-07 29.2 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 EDN95695.1 - 7.2e-15 54.8 2.7 5.2e-06 26.4 1.0 4.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EDN95695.1 - 1.3e-11 43.8 3.9 0.091 12.3 0.0 5.3 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.1 EDN95695.1 - 2.9e-10 39.0 0.6 3.8e-05 22.8 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EDN95695.1 - 0.011 15.6 0.0 0.93 9.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain Clr5 PF14420.1 EDN95696.1 - 4.2e-20 71.3 2.7 7.4e-20 70.6 1.8 1.4 1 0 0 1 1 1 1 Clr5 domain Kunitz_legume PF00197.13 EDN95696.1 - 0.067 12.7 0.3 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Trypsin and protease inhibitor DUF3368 PF11848.3 EDN95696.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) DDE_1 PF03184.14 EDN95697.1 - 2.7e-48 163.9 0.5 8e-48 162.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95697.1 - 7.6e-09 34.9 0.1 1.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN95697.1 - 8.3e-08 31.9 0.0 4.4e-07 29.6 0.0 2.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN95697.1 - 3.2e-07 30.1 0.0 7.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease ATXN-1_C PF12547.3 EDN95697.1 - 0.056 13.4 0.4 0.16 11.9 0.3 1.8 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator zf-CCHC PF00098.18 EDN95697.1 - 0.08 12.9 5.1 0.2 11.6 3.5 1.7 1 0 0 1 1 1 0 Zinc knuckle HTH_3 PF01381.17 EDN95697.1 - 0.11 12.3 0.1 0.4 10.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix NUMOD1 PF07453.8 EDN95697.1 - 0.13 12.1 0.3 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 NUMOD1 domain zf-CCHC_4 PF14392.1 EDN95697.1 - 0.37 10.5 3.4 0.9 9.2 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle RNA_pol_Rpc4 PF05132.9 EDN95698.1 - 7e-30 103.6 0.1 7e-30 103.6 0.0 3.6 3 1 0 3 3 3 1 RNA polymerase III RPC4 CENP-N PF05238.8 EDN95698.1 - 5.7 5.8 7.3 6.8 5.6 2.2 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like FAD_binding_3 PF01494.14 EDN95699.1 - 8.5e-15 54.6 0.0 3.3e-06 26.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN95699.1 - 4.2e-09 35.7 0.1 0.0011 17.9 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN95699.1 - 2.4e-05 23.4 0.3 0.00035 19.6 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EDN95699.1 - 4.9e-05 21.9 0.3 0.042 12.3 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EDN95699.1 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDN95699.1 - 0.00028 20.1 0.1 0.0026 16.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EDN95699.1 - 0.0004 19.3 1.6 0.00083 18.3 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EDN95699.1 - 0.00085 19.3 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN95699.1 - 0.0035 17.2 0.1 0.01 15.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN95699.1 - 0.0078 14.8 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 EDN95699.1 - 0.015 15.7 0.2 0.37 11.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDN95699.1 - 0.026 13.3 0.3 0.12 11.2 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_76 PF03663.9 EDN95700.1 - 1.4e-130 435.9 19.8 1.9e-130 435.5 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tropomyosin_1 PF12718.2 EDN95702.1 - 0.0012 18.6 7.3 0.0012 18.6 5.1 2.1 2 1 0 2 2 2 1 Tropomyosin like vATP-synt_E PF01991.13 EDN95702.1 - 0.014 14.6 6.0 0.029 13.6 4.2 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Pkip-1 PF06878.6 EDN95702.1 - 0.017 15.0 4.9 0.031 14.1 3.4 1.4 1 0 0 1 1 1 0 Pkip-1 protein Spc24 PF08286.6 EDN95702.1 - 0.019 14.6 10.6 0.36 10.5 1.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 EDN95702.1 - 0.022 14.5 13.4 0.028 14.2 3.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCLC PF05934.6 EDN95702.1 - 0.023 13.0 0.4 0.033 12.5 0.3 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4201 PF13870.1 EDN95702.1 - 0.028 13.8 7.0 0.052 12.9 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Coatomer_E PF04733.9 EDN95702.1 - 0.031 13.4 1.6 0.054 12.6 1.1 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit AAA_13 PF13166.1 EDN95702.1 - 0.036 12.5 5.9 0.056 11.9 4.1 1.2 1 0 0 1 1 1 0 AAA domain SNARE PF05739.14 EDN95702.1 - 0.042 13.5 0.5 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 SNARE domain IncA PF04156.9 EDN95702.1 - 0.05 13.1 15.4 0.014 14.9 8.6 1.7 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EDN95702.1 - 0.057 12.4 6.6 0.11 11.5 4.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 TROVE PF05731.6 EDN95702.1 - 0.079 11.7 3.6 0.13 11.0 2.5 1.3 1 0 0 1 1 1 0 TROVE domain Baculo_PEP_C PF04513.7 EDN95702.1 - 0.084 12.6 2.6 0.15 11.8 1.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.11 EDN95702.1 - 0.096 12.7 7.8 0.31 11.0 5.4 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein PilJ PF13675.1 EDN95702.1 - 0.12 12.7 1.8 0.25 11.6 1.2 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Laminin_II PF06009.7 EDN95702.1 - 0.2 11.4 9.4 0.031 14.0 1.6 2.2 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.6 EDN95702.1 - 0.27 11.6 9.4 0.59 10.5 2.3 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EDN95702.1 - 0.29 10.9 8.4 0.34 10.7 0.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 EDN95702.1 - 0.31 11.0 7.9 0.34 10.9 4.2 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 EDN95702.1 - 0.51 10.2 8.3 1.3 8.9 5.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TBPIP PF07106.8 EDN95702.1 - 0.56 9.7 10.1 3 7.3 7.0 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EDN95702.1 - 0.67 9.7 15.2 0.88 9.3 8.6 2.5 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 EDN95702.1 - 1.1 9.3 12.0 0.93 9.5 2.6 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4140 PF13600.1 EDN95702.1 - 1.2 9.5 8.7 4.4 7.8 0.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 EDN95702.1 - 1.2 8.8 11.4 6.1 6.6 6.9 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CCDC-167 PF15188.1 EDN95702.1 - 1.4 8.9 6.1 7.6 6.5 0.7 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Kinetochor_Ybp2 PF08568.5 EDN95705.1 - 7.2e-146 487.0 0.0 8.5e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_hydro_53 PF07745.8 EDN95706.1 - 2.5e-107 358.5 0.1 2.8e-107 358.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 EDN95706.1 - 0.0051 16.0 0.1 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PaaX_C PF08223.6 EDN95706.1 - 0.051 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain DDE_1 PF03184.14 EDN95708.1 - 2.8e-44 150.8 0.0 4.6e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95708.1 - 6.7e-06 25.5 0.2 6.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN95708.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN95708.1 - 0.019 14.8 7.3 0.042 13.8 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_tran_WecB PF03808.8 EDN95708.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HSP70 PF00012.15 EDN95710.1 - 0.0001 20.3 0.1 0.0016 16.4 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein Sugar_tr PF00083.19 EDN95712.1 - 6.3e-93 311.7 27.2 7.5e-93 311.5 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN95712.1 - 9e-24 83.8 25.4 9e-24 83.8 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LtrA PF06772.6 EDN95713.1 - 2.5e-21 76.0 20.7 2.5e-21 76.0 14.4 1.5 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DNA_pol_A PF00476.15 EDN95714.1 - 1.2e-99 333.5 0.0 7.6e-92 307.8 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase family A zf-C3HC4_3 PF13920.1 EDN95715.1 - 1.1e-10 40.9 7.8 1.6e-10 40.4 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN95715.1 - 4.5e-10 39.1 9.9 7.1e-10 38.5 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN95715.1 - 4.6e-09 36.1 9.5 7.2e-09 35.5 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN95715.1 - 3.1e-08 33.1 9.7 4.9e-08 32.4 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN95715.1 - 3e-07 30.0 9.5 4.7e-07 29.4 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDN95715.1 - 0.0011 18.6 7.9 0.016 14.8 4.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDN95715.1 - 0.0027 17.5 7.9 0.0046 16.7 5.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDN95715.1 - 0.0035 16.8 5.2 0.0062 16.1 3.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EDN95715.1 - 0.011 15.8 4.4 0.019 15.0 3.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN95715.1 - 0.55 10.1 4.0 0.93 9.3 2.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EDN95715.1 - 0.66 9.8 4.1 1.1 9.0 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EDN95715.1 - 1.5 8.4 10.4 4.9 6.7 7.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PI3_PI4_kinase PF00454.22 EDN95718.1 - 1.1e-49 169.0 0.0 2e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EDN95718.1 - 1.5e-44 152.4 8.8 3.1e-44 151.4 6.1 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EDN95718.1 - 1e-33 115.4 0.3 1.2e-32 112.0 0.1 2.8 2 0 0 2 2 2 1 UME (NUC010) domain TPR_19 PF14559.1 EDN95718.1 - 0.028 14.7 2.0 0.21 11.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN95718.1 - 0.59 10.9 5.4 11 6.9 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat COX16 PF14138.1 EDN95719.1 - 1.9e-32 111.2 0.1 2.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF4215 PF13948.1 EDN95721.1 - 6.6e-07 29.4 3.0 2e-06 27.8 2.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) Abhydrolase_3 PF07859.8 EDN95722.1 - 1.2e-24 87.0 0.0 1.5e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN95722.1 - 3.3e-12 45.7 0.0 4.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EDN95722.1 - 0.0054 15.9 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DDE_1 PF03184.14 EDN95723.1 - 6.5e-51 172.5 0.0 1.5e-50 171.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95723.1 - 4.4e-10 39.2 1.0 1.2e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN95723.1 - 3.3e-08 33.4 0.0 6.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN95723.1 - 0.005 16.7 6.0 0.012 15.4 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDN95723.1 - 0.076 13.3 0.6 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) PFK PF00365.15 EDN95724.1 - 7.6e-163 540.2 1.5 1.3e-117 391.7 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Med17 PF10156.4 EDN95725.1 - 2.6e-108 362.2 0.0 3.1e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex zf-PARP PF00645.13 EDN95726.1 - 4.1e-23 81.4 0.1 1.6e-22 79.5 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PIG-L PF02585.12 EDN95727.1 - 1e-27 97.1 0.0 1.3e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Abi PF02517.11 EDN95728.1 - 6.9 6.8 9.7 43 4.3 6.8 2.4 1 1 0 1 1 1 0 CAAX protease self-immunity MFS_1 PF07690.11 EDN95730.1 - 1.9e-26 92.6 34.7 2.4e-26 92.3 24.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GTP_EFTU PF00009.22 EDN95732.1 - 3.8e-21 75.3 0.0 7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN95732.1 - 1.4e-14 54.0 0.0 3.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN95732.1 - 3.3e-11 43.1 1.4 5.4e-10 39.2 0.7 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EDN95732.1 - 0.0062 17.0 0.0 0.089 13.2 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EDN95732.1 - 0.0087 15.5 1.2 0.61 9.5 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EDN95732.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDN95732.1 - 0.08 12.5 0.9 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 LSM PF01423.17 EDN95733.1 - 7.4e-09 35.0 0.1 1.1e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF2179 PF10035.4 EDN95733.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) ATP13 PF12921.2 EDN95734.1 - 1.6e-39 134.0 0.0 3.1e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EDN95734.1 - 0.0097 15.8 0.3 2.5 8.1 0.0 3.6 4 0 0 4 4 4 1 PPR repeat family AAA_12 PF13087.1 EDN95735.1 - 1.7e-36 125.4 0.0 1.1e-35 122.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDN95735.1 - 2.7e-22 79.4 0.0 7.2e-22 78.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDN95735.1 - 8.6e-10 38.5 0.0 3.3e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EDN95735.1 - 1.7e-08 34.1 0.0 3.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EDN95735.1 - 5.1e-06 26.1 0.0 0.033 13.7 0.0 3.4 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EDN95735.1 - 0.0079 15.2 0.2 0.26 10.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EDN95735.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN95735.1 - 0.012 14.8 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EDN95735.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EDN95736.1 - 3.9e-17 61.3 3.1 0.048 13.5 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat p450 PF00067.17 EDN95740.1 - 0.00043 18.9 0.0 0.00047 18.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN95742.1 - 2.5e-18 65.8 0.0 2.9e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PROCT PF08084.6 EDN95742.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain Methyltransf_14 PF08484.6 EDN95742.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Med16 PF11635.3 EDN95744.1 - 0.16 9.8 0.4 0.22 9.4 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 2OG-FeII_Oxy_3 PF13640.1 EDN95745.1 - 1.4e-05 25.5 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EDN95745.1 - 0.0043 17.3 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Exo_endo_phos PF03372.18 EDN95747.1 - 1.5e-19 70.8 0.1 1.9e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EDN95749.1 - 2e-17 62.9 46.4 2e-17 62.9 32.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN95749.1 - 8.6e-07 27.5 22.1 1.5e-06 26.7 15.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1749 PF08538.5 EDN95750.1 - 2.1e-93 312.5 0.0 2.5e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EDN95750.1 - 3.1e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN95750.1 - 7.4e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN95750.1 - 0.00035 20.2 0.0 0.0037 16.8 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 EDN95750.1 - 0.0026 17.1 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 EDN95750.1 - 0.015 14.7 0.1 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EDN95750.1 - 0.056 12.3 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cutinase PF01083.17 EDN95750.1 - 0.064 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase XPA_C PF05181.7 EDN95750.1 - 0.095 12.3 0.3 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 XPA protein C-terminus Abhydrolase_2 PF02230.11 EDN95750.1 - 0.13 11.6 0.0 0.87 8.9 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Adaptin_binding PF10199.4 EDN95752.1 - 7.2e-20 71.6 7.5 1.2e-19 70.9 5.2 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 GvpH PF05455.6 EDN95752.1 - 0.08 12.5 2.4 0.13 11.8 1.7 1.3 1 0 0 1 1 1 0 GvpH Tom22 PF04281.8 EDN95752.1 - 0.12 11.9 1.7 0.16 11.5 0.9 1.5 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF773 PF05600.7 EDN95752.1 - 0.24 10.1 2.2 0.3 9.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) PGP_phosphatase PF09419.5 EDN95753.1 - 2.2e-65 219.0 0.0 2.9e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EDN95753.1 - 0.00027 20.5 0.0 0.00062 19.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Homeobox PF00046.24 EDN95756.1 - 7.4e-17 60.7 2.0 1.6e-16 59.6 1.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDN95756.1 - 0.0034 17.0 0.1 0.0078 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 EDN95757.1 - 1.8e-20 72.9 0.1 3.2e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase DUF912 PF06024.7 EDN95757.1 - 0.026 14.5 0.1 0.079 13.0 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hydrolase PF00702.21 EDN95758.1 - 1.7e-05 25.3 0.0 2.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN95758.1 - 7.2e-05 22.4 0.1 0.0001 21.9 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN95758.1 - 0.0009 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SelP_N PF04592.9 EDN95758.1 - 4.3 6.6 5.1 6.7 6.0 3.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sec63 PF02889.11 EDN95759.1 - 3.9e-48 164.2 0.0 6.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EDN95759.1 - 7.3e-26 90.6 0.1 2.9e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN95759.1 - 3.1e-09 36.9 0.1 1.4e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN95759.1 - 4.7e-08 32.7 0.0 2e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EDN95759.1 - 0.00079 19.5 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain UvrD-helicase PF00580.16 EDN95759.1 - 0.0015 17.8 0.1 0.028 13.7 0.0 2.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EDN95759.1 - 0.0036 17.4 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN95759.1 - 0.028 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.9 EDN95759.1 - 0.066 12.8 0.0 0.35 10.5 0.0 2.2 2 1 0 3 3 3 0 Helicase AAA_16 PF13191.1 EDN95759.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Nuc_sug_transp PF04142.10 EDN95760.1 - 1.5e-70 237.0 5.9 3.2e-70 235.9 4.1 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EDN95760.1 - 1.9e-09 36.8 10.7 2.2e-08 33.3 7.3 2.0 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EDN95760.1 - 3.8e-05 23.8 13.1 0.00024 21.2 0.6 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EDN95760.1 - 0.038 13.6 21.7 0.76 9.4 10.1 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 EDN95760.1 - 0.048 13.7 25.4 0.084 12.9 4.0 2.6 2 1 0 2 2 2 0 EamA-like transporter family DUF2871 PF11070.3 EDN95760.1 - 0.74 9.9 5.6 3.6 7.7 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2871) HTH_Tnp_Mu_1 PF02316.11 EDN95762.1 - 0.096 12.3 0.6 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 Mu DNA-binding domain PHD_2 PF13831.1 EDN95763.1 - 0.0024 17.1 8.4 0.0056 15.9 5.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EDN95763.1 - 0.011 15.9 0.5 0.038 14.2 0.4 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD PF00628.24 EDN95763.1 - 0.36 10.5 12.4 0.72 9.5 8.6 1.5 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 EDN95765.1 - 6.2e-57 187.5 18.4 5e-10 38.8 0.3 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EDN95765.1 - 5.1e-14 51.7 0.1 1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN95765.1 - 1.4e-12 46.9 0.3 4.5e-12 45.2 0.2 2.0 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EDN95765.1 - 0.00011 20.4 5.2 0.29 9.2 0.0 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EDN95765.1 - 0.00037 20.2 0.0 8.1 6.2 0.0 4.5 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 EDN95765.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.6 1 1 0 1 1 1 0 PRANC domain DUF1629 PF07791.6 EDN95765.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) NDUF_B7 PF05676.8 EDN95766.1 - 2.3e-32 110.1 2.6 3e-32 109.8 1.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PepSY_2 PF13670.1 EDN95768.1 - 2.4 8.0 5.2 4 7.4 3.6 1.7 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Aha1_N PF09229.6 EDN95769.1 - 3.9e-37 127.1 1.2 7e-37 126.3 0.8 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EDN95769.1 - 1.4e-19 70.3 0.1 3.9e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EDN95769.1 - 0.0062 16.7 0.9 0.058 13.5 0.3 2.2 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Alkyl_sulf_dimr PF14863.1 EDN95770.1 - 2.4e-53 180.1 0.0 6.8e-53 178.6 0.0 1.7 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EDN95770.1 - 3.8e-28 97.9 0.3 7.6e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EDN95770.1 - 8.4e-26 90.8 0.2 1.3e-25 90.1 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN95770.1 - 0.0014 18.1 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PEX11 PF05648.9 EDN95771.1 - 0.00062 19.0 0.0 0.00071 18.9 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Complex1_51K PF01512.12 EDN95772.1 - 8.2e-47 158.7 0.0 1.3e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EDN95772.1 - 3.3e-17 61.3 0.5 3.3e-17 61.3 0.4 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EDN95772.1 - 6.7e-10 38.7 0.0 2e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 SLBB domain Hexapep PF00132.19 EDN95773.1 - 0.0042 16.5 13.8 0.04 13.4 0.3 4.5 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN95773.1 - 4.9 6.8 16.2 9 5.9 4.9 3.5 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.7 EDN95774.1 - 2.3e-31 108.2 24.4 2.3e-31 108.2 16.9 16.3 10 3 6 16 16 16 8 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EDN95774.1 - 3.1e-05 23.8 48.9 4.3e-05 23.4 12.8 17.9 8 6 7 17 17 17 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 EDN95774.1 - 0.00032 19.0 23.5 0.00032 19.0 16.3 8.4 2 2 6 8 8 8 3 Plant protein of unknown function (DUF869) DUF4200 PF13863.1 EDN95774.1 - 0.0014 18.6 12.0 0.0014 18.6 8.3 19.4 9 4 9 18 18 18 3 Domain of unknown function (DUF4200) TFIIE_beta PF02186.10 EDN95775.1 - 4.9e-07 29.6 0.1 1.7e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain Pro_isomerase PF00160.16 EDN95776.1 - 3.1e-48 163.8 0.1 3.1e-48 163.8 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mo25 PF08569.6 EDN95776.1 - 0.093 11.7 0.6 0.14 11.1 0.4 1.2 1 0 0 1 1 1 0 Mo25-like Pentapeptide_4 PF13599.1 EDN95777.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) bZIP_2 PF07716.10 EDN95779.1 - 3.1e-06 26.9 19.8 6.5e-06 25.8 13.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN95779.1 - 0.00024 20.9 19.8 0.00038 20.3 13.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDN95779.1 - 0.00033 20.8 17.3 0.00054 20.2 12.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.4 EDN95779.1 - 0.0013 18.5 9.8 0.0023 17.7 6.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 EDN95779.1 - 0.032 13.7 4.4 0.063 12.7 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 EDN95779.1 - 0.26 10.2 7.3 0.37 9.7 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PA26 PF04636.8 EDN95779.1 - 0.74 8.4 4.5 1 7.9 3.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TMEM247 PF15444.1 EDN95779.1 - 0.97 9.2 3.8 1.4 8.6 2.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 zf-C2H2_4 PF13894.1 EDN95784.1 - 0.024 14.9 0.1 0.089 13.1 0.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN95784.1 - 0.6 10.5 0.2 1.6 9.2 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 EDN95785.1 - 0.051 13.9 0.3 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN95785.1 - 0.18 12.0 0.2 0.46 10.7 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PSRT PF07636.6 EDN95786.1 - 0.034 13.6 1.1 0.086 12.3 0.8 1.7 1 0 0 1 1 1 0 PSRT Jnk-SapK_ap_N PF09744.4 EDN95786.1 - 0.38 10.7 9.5 0.098 12.6 3.8 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 RE_TaqI PF09573.5 EDN95787.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 TaqI restriction endonuclease HemY_N PF07219.8 EDN95793.1 - 0.053 13.0 0.2 0.061 12.8 0.2 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DUF4448 PF14610.1 EDN95793.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PAN_1 PF00024.21 EDN95794.1 - 0.00044 19.9 0.5 0.00063 19.4 0.3 1.3 1 0 0 1 1 1 1 PAN domain Penaeidin PF05927.6 EDN95794.1 - 0.0076 16.7 1.5 0.019 15.5 0.3 2.0 1 1 1 2 2 2 1 Penaeidin DcpS_C PF11969.3 EDN95796.1 - 4.1e-17 62.4 1.7 2.2e-16 60.1 1.1 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EDN95796.1 - 5e-15 55.8 0.0 1.1e-14 54.7 0.0 1.5 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 EDN95797.1 - 9.6e-20 70.5 0.7 3.4e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN95797.1 - 6.5e-14 51.5 0.0 4.5e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDN95797.1 - 1.7e-12 47.1 0.0 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 EDN95797.1 - 1.9e-11 43.8 0.1 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EDN95797.1 - 3.6e-09 36.3 0.1 8e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN95797.1 - 0.00014 21.9 0.1 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN95797.1 - 0.0017 17.3 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EDN95797.1 - 0.0038 16.7 0.2 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DND1_DSRM PF14709.1 EDN95797.1 - 0.006 16.8 0.1 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 KaiC PF06745.8 EDN95797.1 - 0.0065 15.6 0.3 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 KaiC ResIII PF04851.10 EDN95797.1 - 0.0072 16.1 0.0 0.031 14.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EDN95797.1 - 0.016 15.5 0.2 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_1 PF03184.14 EDN95798.1 - 2.4e-45 154.3 0.0 4.3e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95798.1 - 1e-07 31.6 0.1 3.8e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN95798.1 - 0.00047 19.9 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN95798.1 - 0.016 15.1 7.3 0.043 13.7 5.1 1.8 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EDN95798.1 - 0.089 12.9 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain DUF302 PF03625.9 EDN95799.1 - 0.00053 19.4 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF302 Anti-adapt_IraP PF10796.4 EDN95799.1 - 0.086 13.2 0.0 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF3159 PF11361.3 EDN95799.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Tim17 PF02466.14 EDN95800.1 - 1.1e-33 115.9 7.5 1.3e-33 115.7 5.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EDN95800.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal DDE_1 PF03184.14 EDN95803.1 - 1.2e-25 89.9 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95803.1 - 1.4e-12 46.9 0.5 3.6e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN95803.1 - 1.7e-09 37.5 0.1 4.3e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95803.1 - 5.8e-05 22.8 0.1 0.00029 20.6 0.0 2.3 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN95803.1 - 0.021 14.9 0.1 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Scaffolding_pro PF11418.3 EDN95803.1 - 0.073 13.3 1.0 0.13 12.6 0.6 1.5 1 1 0 1 1 1 0 Phi29 scaffolding protein NUMOD1 PF07453.8 EDN95803.1 - 0.081 12.7 0.1 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain HTH_28 PF13518.1 EDN95803.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Gly-rich_Ago1 PF12764.2 EDN95804.1 - 4e-05 24.1 27.9 0.0052 17.4 7.7 3.4 3 0 0 3 3 3 3 Glycine-rich region of argonaut CorA PF01544.13 EDN95807.1 - 0.027 13.4 0.5 0.05 12.6 0.1 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Cullin_Nedd8 PF10557.4 EDN95807.1 - 0.042 13.6 0.9 0.089 12.6 0.4 1.7 2 0 0 2 2 2 0 Cullin protein neddylation domain TMF_DNA_bd PF12329.3 EDN95807.1 - 0.071 12.9 6.4 2.1 8.1 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PSI_PsaH PF03244.9 EDN95809.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI FF PF01846.14 EDN95810.1 - 2.3e-09 37.0 0.2 2.3e-09 37.0 0.1 4.3 4 0 0 4 4 4 1 FF domain WW PF00397.21 EDN95810.1 - 1.4e-08 34.4 4.7 1.4e-08 34.4 3.2 2.6 2 0 0 2 2 2 1 WW domain FliL PF03748.9 EDN95810.1 - 0.057 13.4 0.1 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Proteasome PF00227.21 EDN95811.1 - 4.8e-61 205.3 0.1 5.8e-61 205.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN95811.1 - 3.7e-14 51.7 0.2 7.1e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EDN95811.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit BAR_2 PF10455.4 EDN95812.1 - 0.0062 15.4 2.1 0.72 8.7 0.1 2.3 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking SAM_PNT PF02198.11 EDN95816.1 - 0.061 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain p450 PF00067.17 EDN95818.1 - 1.4e-63 215.0 0.0 1e-58 198.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Flavodoxin_1 PF00258.20 EDN95818.1 - 7.9e-20 71.3 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EDN95818.1 - 9.2e-16 57.9 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EDN95818.1 - 7.3e-12 45.8 0.0 2.4e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EDN95818.1 - 7.6e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain WD40 PF00400.27 EDN95820.1 - 1.3e-22 78.7 2.0 1.4e-15 56.4 0.3 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EDN95820.1 - 0.03 12.4 0.0 0.037 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Glyco_hydro_18 PF00704.23 EDN95821.1 - 4.2e-90 302.6 10.1 5e-90 302.4 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IL13 PF03487.8 EDN95821.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin-13 AMA-1 PF02430.10 EDN95822.1 - 0.096 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Apical membrane antigen 1 Gpi16 PF04113.9 EDN95823.1 - 8.2e-91 304.7 0.1 9.5e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Gpi16 PF04113.9 EDN95824.1 - 7.2e-44 149.7 0.1 8.1e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Mitovir_RNA_pol PF05919.6 EDN95824.1 - 0.071 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase LUC7 PF03194.10 EDN95825.1 - 3.2e-71 239.8 0.9 3.9e-71 239.5 0.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Dynamitin PF04912.9 EDN95825.1 - 0.0012 17.7 1.6 0.002 16.9 0.7 1.5 2 0 0 2 2 2 1 Dynamitin zf-C4H2 PF10146.4 EDN95825.1 - 0.0068 16.4 0.5 0.011 15.8 0.4 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein DUF4200 PF13863.1 EDN95825.1 - 0.02 14.8 0.5 0.02 14.8 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) MCPsignal PF00015.16 EDN95825.1 - 0.059 12.9 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MutS_III PF05192.13 EDN95825.1 - 0.13 12.0 0.5 0.19 11.4 0.3 1.2 1 0 0 1 1 1 0 MutS domain III GRP PF07172.6 EDN95825.1 - 2.5 8.6 22.5 0.74 10.3 13.4 1.7 2 0 0 2 2 2 0 Glycine rich protein family Occludin_ELL PF07303.8 EDN95825.1 - 2.7 8.7 7.0 2.3 9.0 0.2 2.9 1 1 1 3 3 3 0 Occludin homology domain zf-His_Me_endon PF05551.6 EDN95828.1 - 2.4e-32 111.6 0.2 3.2e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Zea_mays_MuDR PF05928.6 EDN95829.1 - 0.0038 16.6 0.0 0.0045 16.4 0.0 1.0 1 0 0 1 1 1 1 Zea mays MURB-like protein (MuDR) Packaging_FI PF14000.1 EDN95829.1 - 0.0056 16.8 1.3 0.0085 16.2 0.6 1.5 1 1 0 1 1 1 1 DNA packaging protein FI FCP1_C PF09309.5 EDN95829.1 - 0.035 13.4 3.3 0.039 13.2 2.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF3373 PF11853.3 EDN95829.1 - 0.046 12.2 0.2 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) YscO PF07321.7 EDN95829.1 - 0.44 10.3 8.1 0.61 9.9 5.6 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Med9 PF07544.8 EDN95829.1 - 8.5 6.1 13.3 0.84 9.4 0.8 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HTH_Tnp_Tc5 PF03221.11 EDN95830.1 - 7.3e-15 54.5 0.2 2.5e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN95830.1 - 2.2e-10 40.0 0.2 5.5e-10 38.7 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95830.1 - 1.9e-08 33.6 0.0 3.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDN95830.1 - 0.0015 18.3 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 NUMOD1 domain HTH_23 PF13384.1 EDN95830.1 - 0.02 14.5 0.1 1.4 8.7 0.0 2.6 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EDN95830.1 - 0.051 13.5 0.1 0.58 10.1 0.0 2.2 1 1 0 2 2 2 0 Transposase DDE_1 PF03184.14 EDN95831.1 - 7.8e-47 159.2 0.0 1.2e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95831.1 - 1.2e-10 40.7 0.6 1.3e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN95831.1 - 4.1e-05 23.3 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDN95831.1 - 0.015 15.1 0.2 0.047 13.5 0.2 1.9 1 0 0 1 1 1 0 NUMOD1 domain HTH_37 PF13744.1 EDN95831.1 - 0.16 11.7 1.1 0.38 10.6 0.3 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain MFS_1 PF07690.11 EDN95832.1 - 1.7e-41 142.1 31.7 1.7e-41 142.1 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN95832.1 - 4.6e-14 51.8 12.8 4.6e-14 51.8 8.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EDN95832.1 - 2.3e-06 26.1 3.1 2.3e-06 26.1 2.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 EDN95834.1 - 2.9 7.8 11.4 0.8 9.6 5.3 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B_2 PF12706.2 EDN95835.1 - 2.4e-26 92.4 0.0 3.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDN95835.1 - 6.3e-12 45.5 0.1 1e-11 44.7 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Se-cys_synth_N PF12390.3 EDN95835.1 - 0.35 10.9 1.6 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Selenocysteine synthase N terminal DDE_1 PF03184.14 EDN95836.1 - 1.5e-52 177.8 0.2 7.6e-52 175.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95836.1 - 6.4e-09 35.4 0.7 1.8e-08 34.0 0.0 2.2 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain RNase_PH PF01138.16 EDN95837.1 - 3.3e-34 118.0 0.1 6.2e-34 117.1 0.1 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.15 EDN95838.1 - 6.7e-33 112.4 0.1 4.1e-25 87.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EDN95838.1 - 9.1e-09 35.5 0.6 0.0019 18.3 0.1 2.8 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN95838.1 - 4.4e-06 26.7 0.1 0.0055 16.7 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.16 EDN95838.1 - 0.0053 16.4 0.1 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EDN95838.1 - 0.011 15.7 0.1 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EDN95838.1 - 0.091 12.5 0.2 1.2 8.9 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin domain DUF605 PF04652.11 EDN95839.1 - 6.7e-116 387.8 14.8 7.6e-116 387.6 10.2 1.0 1 0 0 1 1 1 1 Vta1 like OPT PF03169.10 EDN95842.1 - 1.4e-134 449.9 44.4 1.6e-134 449.7 30.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EDN95842.1 - 0.38 9.8 1.0 1.1 8.3 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.4 EDN95842.1 - 1.5 7.2 7.2 0.1 11.1 0.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2077 PF09850.4 EDN95842.1 - 4.5 6.6 4.9 1.2 8.5 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Lipase_GDSL_2 PF13472.1 EDN95843.1 - 3.2e-16 59.9 3.7 3.9e-16 59.7 2.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN95843.1 - 3.1e-09 37.0 2.2 3.8e-09 36.7 1.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rieske PF00355.21 EDN95844.1 - 1.2e-09 37.5 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EDN95844.1 - 1.8e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MtrE PF04206.7 EDN95846.1 - 0.0069 15.4 2.5 0.014 14.4 1.8 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit E VIT1 PF01988.14 EDN95846.1 - 6.3 6.2 12.3 3.1 7.2 5.8 2.2 2 0 0 2 2 2 0 VIT family RasGAP_C PF03836.10 EDN95848.1 - 1.4e-46 157.7 0.7 3.7e-46 156.3 0.5 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EDN95848.1 - 2.7e-44 151.2 0.0 8.9e-44 149.5 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EDN95848.1 - 1.4e-23 80.2 32.1 0.15 11.8 0.0 15.7 16 0 0 16 16 16 8 IQ calmodulin-binding motif CH PF00307.26 EDN95848.1 - 2.4e-11 43.6 0.0 7.5e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 EDN95849.1 - 9.1e-130 432.6 6.5 1.1e-129 432.3 4.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EDN95849.1 - 3.7e-15 55.4 0.0 5.5e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EDN95849.1 - 5.7e-08 32.2 1.7 0.0017 17.6 0.7 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EDN95849.1 - 2.8e-06 26.4 1.5 4.8e-06 25.6 0.3 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EDN95849.1 - 0.0098 15.1 1.5 0.69 9.1 0.1 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein DUF1273 PF06908.6 EDN95849.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Tmemb_185A PF10269.4 EDN95851.1 - 0.0031 17.1 2.5 0.074 12.6 0.3 2.3 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein Glyco_hydro_28 PF00295.12 EDN95852.1 - 5e-33 114.4 6.5 4.3e-32 111.3 4.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_61 PF03443.9 EDN95854.1 - 1e-42 146.3 0.2 1.6e-42 145.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ING PF12998.2 EDN95855.1 - 0.2 11.9 1.7 0.31 11.3 1.2 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding FAD_binding_3 PF01494.14 EDN95857.1 - 2.9e-13 49.6 1.3 1.7e-10 40.5 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EDN95857.1 - 5.4e-06 25.4 0.0 0.00018 20.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 EDN95857.1 - 0.0029 17.3 0.2 0.012 15.4 0.2 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN95857.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN95857.1 - 0.067 13.2 0.9 0.16 11.9 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN95857.1 - 0.089 11.6 0.2 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.13 EDN95858.1 - 3.5e-10 39.1 0.1 7.7e-10 38.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RPE65 PF03055.10 EDN95859.1 - 2.4e-121 405.6 0.0 2.7e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein O-FucT PF10250.4 EDN95861.1 - 2.9e-09 36.4 0.0 1.9e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Terminase_1 PF03354.10 EDN95861.1 - 0.029 12.7 0.1 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase ABC_tran PF00005.22 EDN95865.1 - 5.7e-48 162.6 0.7 1.3e-26 93.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EDN95865.1 - 8.7e-32 110.4 58.6 1.3e-25 90.1 20.4 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EDN95865.1 - 1.4e-21 77.7 2.1 0.00013 22.0 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EDN95865.1 - 6.9e-10 38.3 4.3 4.9e-05 22.7 0.6 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN95865.1 - 1.9e-08 34.9 4.9 0.0014 18.9 0.3 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EDN95865.1 - 3.4e-07 29.7 4.3 0.087 12.0 0.1 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN95865.1 - 6.2e-05 23.0 0.3 0.35 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EDN95865.1 - 0.00017 20.8 1.3 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EDN95865.1 - 0.0015 17.7 0.1 0.26 10.2 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDN95865.1 - 0.0027 17.8 0.1 0.51 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 EDN95865.1 - 0.0033 16.8 0.4 0.11 11.8 0.1 2.4 2 0 0 2 2 2 1 MutS domain V AAA_30 PF13604.1 EDN95865.1 - 0.0037 16.8 0.4 1.4 8.4 0.2 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN95865.1 - 0.0066 15.8 0.4 3.7 6.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN95865.1 - 0.021 13.8 0.2 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EDN95865.1 - 0.026 14.2 6.4 2.5 7.9 0.5 4.0 4 0 0 4 4 3 0 Part of AAA domain AAA_33 PF13671.1 EDN95865.1 - 0.036 13.9 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDN95865.1 - 0.037 13.9 1.4 1.8 8.5 0.5 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EDN95865.1 - 0.072 13.0 0.6 6.4 6.7 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EDN95865.1 - 0.1 12.0 1.3 12 5.3 0.4 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EDN95865.1 - 0.12 11.7 1.1 8.9 5.6 0.4 2.3 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 EDN95865.1 - 0.17 12.3 0.0 6.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EDN95865.1 - 0.19 10.4 0.0 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 EDN95865.1 - 0.45 9.1 0.0 5.9 5.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 EDN95865.1 - 0.54 8.6 0.8 5.7 5.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain Herpes_BMRF2 PF04633.7 EDN95866.1 - 0.0063 15.5 0.3 0.0075 15.2 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus BMRF2 protein 2TM PF13239.1 EDN95866.1 - 0.082 12.9 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 2TM domain ST7 PF04184.7 EDN95866.1 - 0.093 10.9 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 ST7 protein Lactate_perm PF02652.9 EDN95866.1 - 0.14 10.6 0.5 0.18 10.3 0.4 1.0 1 0 0 1 1 1 0 L-lactate permease NUDIX PF00293.23 EDN95867.1 - 5e-15 55.3 0.0 3.1e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain Tim17 PF02466.14 EDN95869.1 - 0.027 14.4 1.8 0.054 13.5 1.0 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Pro_dh PF01619.13 EDN95870.1 - 1.3e-34 119.6 0.2 5.7e-27 94.5 0.0 2.1 2 0 0 2 2 2 2 Proline dehydrogenase FAD_binding_7 PF03441.9 EDN95871.1 - 3.3e-99 331.5 1.7 4.1e-99 331.2 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EDN95871.1 - 3.7e-41 140.6 1.0 1.7e-40 138.4 0.0 2.3 3 0 0 3 3 3 1 DNA photolyase Ribosomal_S21e PF01249.13 EDN95872.1 - 4.6e-42 141.8 0.1 5.2e-42 141.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 EDN95873.1 - 4.7e-23 80.6 0.1 9.5e-23 79.7 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Malic_M PF03949.10 EDN95874.1 - 1.9e-82 276.6 0.0 2.5e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDN95874.1 - 1.4e-68 230.0 0.0 2.2e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3715 PF12509.3 EDN95874.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) AlaDh_PNT_C PF01262.16 EDN95874.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YqgF PF14639.1 EDN95874.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 zf-C2H2 PF00096.21 EDN95876.1 - 0.00075 19.6 2.8 0.021 15.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN95876.1 - 0.0014 18.7 1.6 0.054 13.8 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN95876.1 - 0.13 12.4 1.8 8.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PFO_beta_C PF12367.3 EDN95877.1 - 0.068 13.1 0.9 0.1 12.5 0.6 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DUF3876 PF12992.2 EDN95877.1 - 0.084 12.8 0.3 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF1768 PF08719.6 EDN95879.1 - 7.4e-46 155.7 0.2 9.1e-46 155.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Med2 PF11214.3 EDN95879.1 - 8.2 6.5 13.2 2.5 8.1 0.2 2.7 2 1 1 3 3 3 0 Mediator complex subunit 2 RRM_1 PF00076.17 EDN95880.1 - 2.4e-06 27.1 0.0 0.00016 21.2 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN95880.1 - 0.0002 21.2 0.0 0.0054 16.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN95880.1 - 0.0011 18.7 0.4 0.61 9.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1827 PF08860.5 EDN95880.1 - 0.14 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Gly_transf_sug PF04488.10 EDN95881.1 - 0.0035 17.7 0.0 0.0083 16.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif BTB PF00651.26 EDN95883.1 - 6.9e-05 22.7 0.1 0.002 18.1 0.0 2.1 2 0 0 2 2 2 2 BTB/POZ domain CGI-121 PF08617.5 EDN95885.1 - 4.9e-57 192.1 0.0 5.8e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.13 EDN95886.1 - 1.6e-22 79.6 0.3 3e-22 78.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN95886.1 - 0.00049 19.9 1.4 0.0009 19.1 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 EDN95887.1 - 1.5e-116 388.7 0.2 2.3e-116 388.1 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 EDN95887.1 - 0.011 15.6 0.0 0.043 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc5 PF03221.11 EDN95889.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF971 PF06155.7 EDN95890.1 - 0.023 15.1 0.2 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Collagen PF01391.13 EDN95891.1 - 0.00048 19.6 3.4 0.00069 19.1 2.4 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-RING-like PF08746.6 EDN95891.1 - 0.14 12.1 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 RING-like domain DUF3791 PF12668.2 EDN95893.1 - 0.098 12.2 0.6 0.4 10.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) TFR_dimer PF04253.10 EDN95895.1 - 1.1e-19 70.2 0.0 1.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDN95895.1 - 2.2e-15 56.8 0.0 4.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDN95895.1 - 8.9e-05 22.1 0.0 0.00022 20.8 0.0 1.7 1 0 0 1 1 1 1 PA domain MFS_1 PF07690.11 EDN95896.1 - 7.5e-33 113.6 45.9 1.7e-31 109.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN95896.1 - 5.8e-10 38.3 4.4 5.8e-10 38.3 3.1 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDN95896.1 - 0.0065 14.7 0.6 0.0065 14.7 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BTB PF00651.26 EDN95897.1 - 3.6e-06 26.9 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RVT_1 PF00078.22 EDN95898.1 - 2.2e-28 99.1 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PG_binding_3 PF09374.5 EDN95898.1 - 0.023 14.6 0.2 0.32 10.9 0.0 2.9 4 0 0 4 4 4 0 Predicted Peptidoglycan domain ER_lumen_recept PF00810.13 EDN95900.1 - 3.7e-39 134.5 11.5 5.7e-39 133.9 8.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EDN95900.1 - 1.4 8.5 9.9 0.93 9.0 0.2 3.8 2 2 1 3 3 3 0 PQ loop repeat Glyco_hydro_76 PF03663.9 EDN95901.1 - 3.2e-25 89.3 3.2 8.1e-24 84.6 2.2 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Hpr_kinase_C PF07475.7 EDN95901.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF4347 PF14252.1 EDN95903.1 - 0.017 14.5 0.1 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) DUF16 PF01519.11 EDN95904.1 - 0.17 12.1 1.4 0.23 11.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF2570 PF10828.3 EDN95904.1 - 1.5 8.4 6.6 2.4 7.7 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) RVT_1 PF00078.22 EDN95905.1 - 8.7e-35 120.0 1.7 1.7e-34 119.0 1.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN95905.1 - 2.3e-19 69.1 0.1 6.5e-19 67.7 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN95905.1 - 1.5e-14 54.4 0.5 5.9e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EDN95905.1 - 0.00026 21.0 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDN95905.1 - 0.062 12.9 0.3 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle ADH_N PF08240.7 EDN95906.1 - 5.9e-29 100.0 5.7 9.6e-29 99.3 3.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN95906.1 - 1.8e-20 72.8 0.1 2.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EDN95906.1 - 0.0025 17.4 0.1 0.004 16.7 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 EDN95906.1 - 0.016 16.1 0.0 0.03 15.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN95906.1 - 0.026 13.6 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EDN95906.1 - 0.11 12.3 0.9 0.2 11.4 0.6 1.4 1 0 0 1 1 1 0 ThiF family DDE_1 PF03184.14 EDN95907.1 - 5.7e-44 149.8 0.1 3.9e-43 147.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95907.1 - 2.1e-14 52.7 0.5 6.4e-14 51.2 0.1 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN95907.1 - 5.8e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN95907.1 - 1.8e-08 34.0 1.6 3.9e-08 33.0 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN95907.1 - 0.00066 19.7 0.1 0.0028 17.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_3 PF01381.17 EDN95907.1 - 0.0022 17.7 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN95907.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 NUMOD1 domain AMP-binding PF00501.23 EDN95911.1 - 2.7e-61 207.2 0.0 3.4e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EDN95911.1 - 2.6e-32 112.9 0.0 6.4e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EDN95911.1 - 3.5e-07 30.3 0.0 1.1e-06 28.7 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN95911.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EDN95911.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 EDN95911.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase VirJ PF06057.6 EDN95911.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) YrhC PF14143.1 EDN95912.1 - 0.038 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 YrhC-like protein DDE_1 PF03184.14 EDN95913.1 - 9.6e-36 122.9 4.5 3.9e-35 120.9 0.2 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95913.1 - 4.2e-12 45.3 0.4 1.3e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN95913.1 - 1.3e-10 40.9 0.0 4.4e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDN95913.1 - 0.0019 18.0 0.0 0.0058 16.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN95913.1 - 0.0044 16.8 0.8 0.013 15.2 0.1 2.2 2 0 0 2 2 2 1 NUMOD1 domain HTH_37 PF13744.1 EDN95913.1 - 0.025 14.3 0.4 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 EDN95913.1 - 0.032 14.2 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Zwint PF15556.1 EDN95913.1 - 0.076 12.2 0.4 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 ZW10 interactor HTH_24 PF13412.1 EDN95913.1 - 0.092 12.1 0.2 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF320 PF03777.8 EDN95914.1 - 0.065 13.0 5.7 0.44 10.3 0.1 3.5 3 1 0 3 3 3 0 Small secreted domain (DUF320) RVT_1 PF00078.22 EDN95917.1 - 7.4e-36 123.5 1.6 8.7e-36 123.2 0.4 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN95917.1 - 0.025 14.1 0.6 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF3435 PF11917.3 EDN95920.1 - 5.7e-21 74.7 3.8 1.5e-20 73.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3435) RNase_H PF00075.19 EDN95921.1 - 1.5e-11 44.7 0.1 2.7e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 RNase H DUF993 PF06187.6 EDN95921.1 - 0.012 14.1 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) RVT_1 PF00078.22 EDN95921.1 - 0.13 11.5 0.0 0.76 9.0 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EDN95923.1 - 1e-49 169.1 53.4 2.1e-49 168.1 35.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN95923.1 - 2.2e-15 55.9 21.9 8.8e-15 53.9 15.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN95923.1 - 2.2e-14 52.9 15.7 2.2e-14 52.9 10.9 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2635 PF10948.3 EDN95923.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) RRM_1 PF00076.17 EDN95924.1 - 3.6e-15 55.3 0.0 5.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN95924.1 - 8.6e-12 44.8 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN95924.1 - 2.2e-07 30.6 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.14 EDN95926.1 - 2.2e-54 184.6 0.0 2.9e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN95926.1 - 2.2e-35 122.0 0.0 3.4e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDN95926.1 - 0.00045 19.2 0.0 0.0045 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN95926.1 - 0.0014 18.5 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF3401 PF11881.3 EDN95926.1 - 0.083 12.2 0.4 1.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3401) Pyr_redox PF00070.22 EDN95926.1 - 0.17 12.2 1.1 3 8.3 0.0 2.9 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase BNR_2 PF13088.1 EDN95928.1 - 0.0014 17.9 0.1 0.37 10.0 0.0 3.0 3 1 0 3 3 3 2 BNR repeat-like domain MFS_1 PF07690.11 EDN95929.1 - 7.1e-39 133.4 40.9 1e-37 129.7 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN95929.1 - 3.6e-08 32.4 26.5 8.4e-07 27.9 17.3 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDN95929.1 - 0.012 13.8 8.7 0.0039 15.4 3.2 2.0 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2681 PF10883.3 EDN95929.1 - 0.032 14.4 0.1 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF1049 PF06305.6 EDN95929.1 - 0.17 11.4 0.1 0.17 11.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Myosin_tail_1 PF01576.14 EDN95935.1 - 0.00011 20.1 8.3 0.00017 19.4 5.8 1.2 1 0 0 1 1 1 1 Myosin tail bZIP_1 PF00170.16 EDN95935.1 - 0.0031 17.4 2.2 0.0031 17.4 1.6 3.3 3 1 1 4 4 3 1 bZIP transcription factor Ax_dynein_light PF10211.4 EDN95935.1 - 0.0037 17.1 5.4 0.0037 17.1 3.8 2.1 1 1 1 2 2 2 2 Axonemal dynein light chain Fmp27_WPPW PF10359.4 EDN95935.1 - 0.0049 15.3 6.9 0.0072 14.7 4.8 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CCDC155 PF14662.1 EDN95935.1 - 0.0057 16.2 11.1 0.011 15.4 7.7 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Tropomyosin_1 PF12718.2 EDN95935.1 - 0.012 15.4 14.4 0.087 12.6 10.0 2.2 1 1 0 1 1 1 0 Tropomyosin like DUF812 PF05667.6 EDN95935.1 - 0.014 13.8 8.3 0.021 13.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.6 EDN95935.1 - 0.015 15.0 12.9 0.027 14.3 9.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.6 EDN95935.1 - 0.021 14.6 4.0 0.038 13.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DnaJ PF00226.26 EDN95935.1 - 0.022 14.4 1.6 0.058 13.1 0.1 2.2 2 0 0 2 2 2 0 DnaJ domain Atg14 PF10186.4 EDN95935.1 - 0.029 13.3 10.0 0.044 12.7 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EDN95935.1 - 0.054 12.7 15.5 0.036 13.3 9.2 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EDN95935.1 - 0.072 12.9 11.2 0.37 10.6 5.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec34 PF04136.10 EDN95935.1 - 0.077 12.6 3.2 0.14 11.8 2.2 1.4 1 0 0 1 1 1 0 Sec34-like family Ssu72 PF04722.8 EDN95935.1 - 0.078 12.2 2.1 0.36 10.1 0.8 2.1 2 0 0 2 2 2 0 Ssu72-like protein Filament PF00038.16 EDN95935.1 - 0.084 12.3 12.1 0.034 13.6 6.4 1.7 2 1 0 2 2 1 0 Intermediate filament protein DUF2353 PF09789.4 EDN95935.1 - 0.11 11.7 8.5 0.17 11.1 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 EDN95935.1 - 0.15 11.6 17.5 0.19 11.2 11.2 1.8 1 1 0 1 1 1 0 IncA protein Rootletin PF15035.1 EDN95935.1 - 0.15 11.9 14.8 0.39 10.6 10.2 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TBPIP PF07106.8 EDN95935.1 - 0.24 10.9 8.3 0.74 9.3 5.8 1.8 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fzo_mitofusin PF04799.8 EDN95935.1 - 0.27 10.5 3.5 0.52 9.6 2.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region CENP-F_leu_zip PF10473.4 EDN95935.1 - 0.32 10.8 12.2 0.36 10.6 6.8 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rho_Binding PF08912.6 EDN95935.1 - 0.36 11.1 6.5 1.9 8.8 4.5 2.2 1 1 0 1 1 1 0 Rho Binding DUF972 PF06156.8 EDN95935.1 - 0.51 10.7 7.2 0.9 9.9 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CCDC92 PF14916.1 EDN95935.1 - 0.52 9.9 8.1 0.2 11.2 0.6 3.2 2 1 2 4 4 3 0 Coiled-coil domain of unknown function V_ATPase_I PF01496.14 EDN95935.1 - 0.59 7.9 6.3 0.8 7.4 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 EDN95935.1 - 0.65 10.0 14.5 0.15 12.0 4.2 2.8 1 1 2 3 3 3 0 DivIVA protein Tup_N PF08581.5 EDN95935.1 - 0.8 9.9 9.3 1.2 9.3 5.2 2.3 2 1 0 2 2 1 0 Tup N-terminal ADIP PF11559.3 EDN95935.1 - 0.84 9.5 14.9 0.67 9.8 5.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 EDN95935.1 - 1 9.0 13.9 0.64 9.6 7.5 2.0 1 1 1 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 EDN95935.1 - 1.1 9.3 10.9 0.53 10.3 4.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 EDN95935.1 - 1.1 9.6 14.5 0.25 11.6 2.2 3.0 1 1 2 3 3 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EDN95935.1 - 1.4 7.9 13.3 4.2 6.3 9.2 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EDN95935.1 - 1.7 6.9 5.9 2.8 6.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HCMV_UL139 PF12507.3 EDN95935.1 - 1.8 8.7 6.6 1.9 8.6 0.5 2.9 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein LOH1CR12 PF10158.4 EDN95935.1 - 1.9 8.2 6.0 0.96 9.2 1.9 2.1 3 0 0 3 3 1 0 Tumour suppressor protein DUF4200 PF13863.1 EDN95935.1 - 1.9 8.4 12.2 3.3 7.6 7.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 EDN95935.1 - 2.2 8.7 7.8 7.9 6.9 1.8 3.3 3 1 1 4 4 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EDN95935.1 - 2.7 8.3 11.2 0.44 10.8 1.6 3.4 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EDN95935.1 - 2.9 7.6 16.7 29 4.3 0.0 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EDN95935.1 - 3.5 7.5 4.7 3.8 7.4 0.8 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 EDN95935.1 - 3.9 7.2 12.3 0.82 9.4 4.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EDN95935.1 - 4 7.2 7.3 6.6 6.5 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EDN95935.1 - 5.9 7.1 9.5 5.3 7.2 5.1 2.2 2 1 0 2 2 1 0 Syntaxin Osmo_CC PF08946.5 EDN95935.1 - 5.9 6.9 10.5 30 4.7 0.9 4.1 3 1 1 4 4 4 0 Osmosensory transporter coiled coil FlaC_arch PF05377.6 EDN95935.1 - 6.9 6.6 6.6 8.3 6.3 1.8 3.0 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EDN95935.1 - 7.3 6.1 23.6 0.11 11.9 3.1 3.7 2 1 2 4 4 3 0 Septum formation initiator Sugar_tr PF00083.19 EDN95937.1 - 2e-119 399.1 23.7 3.4e-119 398.3 16.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN95937.1 - 7.6e-30 103.8 55.3 3.8e-27 94.9 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_31 PF13847.1 EDN95938.1 - 0.003 17.1 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDN95938.1 - 0.0037 16.8 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EDN95938.1 - 0.006 15.6 0.0 0.0062 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EDN95938.1 - 0.0079 15.5 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EDN95938.1 - 0.046 13.7 0.1 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDN95938.1 - 0.046 12.7 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EDN95938.1 - 0.075 12.3 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.13 EDN95938.1 - 0.076 12.5 0.0 0.083 12.4 0.0 1.0 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HHH_8 PF14716.1 EDN95938.1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain CMAS PF02353.15 EDN95938.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Amidase PF01425.16 EDN95939.1 - 2.4e-96 323.2 0.0 2.8e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.22 EDN95940.1 - 0.0014 18.3 0.3 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN95940.1 - 0.058 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Metallophos PF00149.23 EDN95941.1 - 9.7e-12 44.6 2.7 7e-11 41.8 1.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ PF00226.26 EDN95941.1 - 0.0078 15.9 0.1 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain DUF993 PF06187.6 EDN95941.1 - 0.1 11.1 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Syntaphilin PF15290.1 EDN95941.1 - 0.51 9.7 2.1 0.78 9.1 1.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp NTR2 PF15458.1 EDN95942.1 - 4.8e-68 229.1 17.7 4.8e-68 229.1 12.3 1.8 2 0 0 2 2 2 1 Nineteen complex-related protein 2 KAR PF15222.1 EDN95942.1 - 0.062 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Kidney androgen-regulated HlyD PF00529.15 EDN95942.1 - 0.093 12.0 7.5 0.18 11.0 5.2 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Toxin_43 PF15604.1 EDN95942.1 - 0.54 10.2 12.0 0.072 13.1 3.4 2.5 2 0 0 2 2 2 0 Putative toxin 43 LSM PF01423.17 EDN95943.1 - 1.4e-19 69.4 0.8 1.6e-19 69.1 0.5 1.1 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.15 EDN95944.1 - 2.4e-08 34.3 0.0 3.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain GNAT_acetyltr_2 PF13718.1 EDN95945.1 - 4.4e-80 267.6 0.0 7.8e-80 266.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EDN95945.1 - 2.1e-66 222.8 0.0 7.9e-66 221.0 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EDN95945.1 - 1.3e-40 136.9 0.1 3.9e-40 135.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EDN95945.1 - 1.5e-35 121.3 0.6 4.4e-35 119.8 0.4 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EDN95945.1 - 0.0037 17.4 0.2 0.12 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Acetyltransf_7 PF13508.1 EDN95945.1 - 0.022 14.9 0.0 0.074 13.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.1 EDN95945.1 - 0.026 14.2 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain DUF4559 PF15112.1 EDN95945.1 - 0.59 9.2 3.3 0.23 10.5 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Thiolase_N PF00108.18 EDN95946.1 - 3.4e-98 327.8 0.8 3.4e-98 327.8 0.5 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN95946.1 - 1.5e-44 150.3 0.8 3.3e-44 149.2 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN95946.1 - 1.4e-05 24.7 0.3 1.4e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EDN95946.1 - 0.014 15.0 3.2 0.02 14.5 0.1 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF605 PF04652.11 EDN95946.1 - 0.15 11.4 0.4 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Vta1 like GTP_EFTU PF00009.22 EDN95947.1 - 2.6e-43 147.6 0.0 3.8e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDN95947.1 - 3.4e-18 65.2 0.0 1.2e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EDN95947.1 - 1.6e-15 56.7 0.0 6.7e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EDN95947.1 - 2.7e-09 37.0 0.1 7.5e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDN95947.1 - 4.2e-07 29.7 0.0 9.1e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EDN95947.1 - 8e-05 22.5 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN95947.1 - 0.0059 17.1 0.1 0.031 14.7 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein DUF59 PF01883.14 EDN95949.1 - 4.2e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 SBDS_C PF09377.5 EDN95949.1 - 0.065 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 SBDS protein C-terminal domain DUF3341 PF11821.3 EDN95949.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) HILPDA PF15220.1 EDN95951.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Fungal_trans PF04082.13 EDN95952.1 - 1.6e-10 40.3 0.2 4.7e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN95952.1 - 3.7e-06 26.7 8.2 7.1e-06 25.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 EDN95953.1 - 1e-14 54.1 0.0 3.2e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN95953.1 - 9.2e-10 37.9 0.1 1.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN95953.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PAP_central PF04928.12 EDN95953.1 - 0.076 11.8 0.2 0.096 11.4 0.1 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF2602 PF10782.4 EDN95953.1 - 0.091 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) HTH_24 PF13412.1 EDN95953.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3844 PF12955.2 EDN95959.1 - 5.4e-29 100.3 5.2 1.3e-28 99.1 3.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) UBN2 PF14223.1 EDN95960.1 - 3.3e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN95960.1 - 0.00018 21.0 0.0 0.00047 19.7 0.0 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN95960.1 - 0.032 13.7 0.9 0.032 13.7 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle Consortin_C PF15281.1 EDN95960.1 - 0.056 12.9 1.2 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Consortin C-terminus zf-CCHC PF00098.18 EDN95960.1 - 5.9 7.0 9.1 0.2 11.6 1.8 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.9 EDN95961.1 - 2.9e-73 245.8 0.4 9.6e-73 244.1 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN95961.1 - 0.00057 19.9 0.0 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDN95961.1 - 0.017 14.4 0.1 0.21 10.9 0.1 2.7 2 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4471 PF14740.1 EDN95961.1 - 0.06 12.5 0.4 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4212 PF13937.1 EDN95963.1 - 0.71 9.9 2.9 1.9 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) ABC_membrane PF00664.18 EDN95964.1 - 0.0049 16.3 0.0 0.0051 16.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region UFD1 PF03152.9 EDN95964.1 - 0.017 14.2 0.3 0.02 14.0 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 DUF2097 PF09870.4 EDN95964.1 - 0.023 14.7 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) ABC_tran PF00005.22 EDN95965.1 - 0.055 13.7 0.2 0.088 13.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter CDP-OH_P_transf PF01066.16 EDN95968.1 - 5.1e-17 62.0 2.0 1.1e-16 60.9 1.4 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PCI PF01399.22 EDN95969.1 - 1e-07 32.2 0.0 1.9e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 PCI domain RGS PF00615.14 EDN95970.1 - 5.9e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAP1 PF08601.5 EDN95970.1 - 0.047 13.3 2.2 0.062 12.9 1.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Ribosomal_L31e PF01198.14 EDN95971.1 - 7.6e-37 124.8 0.4 9.5e-37 124.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 EDN95972.1 - 5.4e-49 165.2 0.0 6.4e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN95972.1 - 1.9e-05 24.4 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN95972.1 - 0.00043 20.1 0.6 0.00099 18.9 0.3 1.8 1 1 1 2 2 2 1 RWD domain UEV PF05743.8 EDN95972.1 - 0.0029 17.2 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EDN95973.1 - 5.1e-60 202.8 0.0 6.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN95973.1 - 7.4e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN95973.1 - 5e-08 32.2 0.0 7.3e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN95973.1 - 0.06 13.0 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EDN95973.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EDN95974.1 - 5e-09 35.7 0.0 5e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDN95974.1 - 1.1e-07 31.3 0.1 2.3e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain MTBP_C PF14920.1 EDN95976.1 - 0.051 13.0 2.6 0.076 12.4 1.8 1.2 1 0 0 1 1 1 0 MDM2-binding Ribosomal_L38e PF01781.13 EDN95977.1 - 1e-32 111.6 2.3 1.2e-32 111.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF1395 PF07160.7 EDN95977.1 - 0.065 12.7 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Ish1 PF10281.4 EDN95978.1 - 0.00028 20.8 1.3 0.00088 19.2 0.9 1.8 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DEK_C PF08766.6 EDN95978.1 - 0.037 13.8 0.1 0.088 12.5 0.1 1.6 1 1 0 1 1 1 0 DEK C terminal domain SAP PF02037.22 EDN95978.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 SAP domain Mtr2 PF10429.4 EDN95980.1 - 6.2e-06 26.0 0.0 8.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 EDN95980.1 - 0.0012 19.1 0.0 0.0054 17.1 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain TnpW PF14202.1 EDN95980.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpW tRNA-synt_1g PF09334.6 EDN95981.1 - 6.4e-119 397.1 0.3 1.2e-118 396.1 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDN95981.1 - 1.6e-23 82.5 3.7 5e-12 44.6 0.0 3.7 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDN95981.1 - 4.8e-08 32.4 0.0 0.0035 16.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Peptidase_C28 PF05408.6 EDN95981.1 - 0.061 12.7 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Peripla_BP_3 PF13377.1 EDN95981.1 - 0.063 13.2 0.0 15 5.5 0.0 2.5 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Mago-bind PF09282.5 EDN95982.1 - 0.15 11.6 3.0 0.27 10.8 0.2 2.4 2 0 0 2 2 2 0 Mago binding TFIIF_alpha PF05793.7 EDN95982.1 - 1 7.6 30.2 1.6 6.9 20.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 EDN95982.1 - 10 3.6 11.9 13 3.3 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_10 PF00331.15 EDN95985.1 - 2.4e-95 319.2 0.1 2.7e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 HTH_Tnp_Tc5 PF03221.11 EDN95986.1 - 4e-15 55.3 0.2 1e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN95986.1 - 1.6e-12 47.0 0.3 8.2e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4355 PF14265.1 EDN95987.1 - 0.043 13.7 0.8 0.043 13.7 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) DUF3373 PF11853.3 EDN95987.1 - 0.15 10.5 0.3 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Med9 PF07544.8 EDN95987.1 - 5.3 6.8 8.2 0.26 11.0 0.8 2.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4129 PF13559.1 EDN95989.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) V_ATPase_I PF01496.14 EDN95990.1 - 2e-301 1001.4 0.1 2.3e-301 1001.2 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EDN95990.1 - 0.0075 15.7 5.1 1.6 8.0 0.0 2.7 2 1 0 2 2 2 2 Intermediate filament protein Reo_sigmaC PF04582.7 EDN95990.1 - 0.08 12.1 0.7 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 EDN95990.1 - 0.096 12.1 1.0 0.33 10.4 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Transposase_22 PF02994.9 EDN95990.1 - 0.13 10.6 0.7 0.24 9.8 0.1 1.6 2 0 0 2 2 2 0 L1 transposable element Baculo_PEP_C PF04513.7 EDN95990.1 - 0.28 11.0 4.3 2.7 7.8 0.2 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EDN95990.1 - 1.3 8.5 3.5 4.4 6.8 0.9 2.5 2 0 0 2 2 2 0 IncA protein Aminotran_1_2 PF00155.16 EDN95991.1 - 6.6e-34 117.4 0.0 1e-27 97.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II GMC_oxred_N PF00732.14 EDN95992.1 - 2.8e-53 181.0 0.0 3.6e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN95992.1 - 4.4e-37 127.5 0.1 1.2e-36 126.1 0.1 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN95992.1 - 2.5e-07 29.9 0.3 2.2e-06 26.8 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN95992.1 - 4e-07 29.2 0.1 9.7e-06 24.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN95992.1 - 1.8e-05 24.9 0.7 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN95992.1 - 9.6e-05 22.3 0.1 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN95992.1 - 0.00016 21.6 0.7 0.0005 20.0 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN95992.1 - 0.0011 17.9 0.1 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EDN95992.1 - 0.006 15.6 0.1 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EDN95992.1 - 0.034 12.6 0.1 0.051 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EDN95992.1 - 0.076 12.7 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EDN95992.1 - 0.13 10.9 0.4 0.19 10.2 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EDN95992.1 - 0.2 12.0 0.5 0.53 10.7 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.1 EDN95993.1 - 9.3e-51 171.0 2.8 9e-29 100.0 0.1 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EDN95993.1 - 3.9e-33 114.6 0.1 6.5e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDN95993.1 - 0.0044 17.4 0.4 0.017 15.5 0.1 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EDN95993.1 - 0.013 14.8 1.1 0.38 10.1 0.1 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sulfate_tra_GLY PF13792.1 EDN95993.1 - 2 8.1 5.7 0.72 9.5 0.3 2.7 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif FAD_binding_4 PF01565.18 EDN95994.1 - 5.1e-26 90.8 3.9 8.6e-26 90.0 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN95994.1 - 8.4e-12 44.8 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Taxilin PF09728.4 EDN95998.1 - 5.4e-98 327.8 57.2 7.5e-98 327.4 39.6 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein CENP-Q PF13094.1 EDN95998.1 - 0.0085 16.1 13.5 0.0085 16.1 9.4 4.2 1 1 3 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 EDN95998.1 - 0.2 11.4 54.5 0.08 12.6 4.2 4.6 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.6 EDN95999.1 - 4.3e-63 212.4 0.0 6.7e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EDN95999.1 - 2.1e-34 118.8 0.0 2.8e-18 66.2 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Orn_Arg_deC_N PF02784.11 EDN96001.1 - 1.1e-78 263.8 0.0 1.8e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EDN96001.1 - 5.9e-30 103.3 0.0 1.2e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EDN96001.1 - 0.0034 16.7 0.0 0.0077 15.5 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_M24 PF00557.19 EDN96002.1 - 6.1e-44 150.0 0.3 8.4e-44 149.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDN96002.1 - 1e-09 39.0 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AdoHcyase_NAD PF00670.16 EDN96002.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain OGFr_N PF04664.8 EDN96003.1 - 1.4e-33 116.0 0.0 3e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region HSF_DNA-bind PF00447.12 EDN96003.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 HSF-type DNA-binding DUF4404 PF14357.1 EDN96003.1 - 0.94 9.9 6.1 4 7.9 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Pro-kuma_activ PF09286.6 EDN96004.1 - 5.2e-49 165.9 1.9 5.7e-49 165.8 0.7 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN96004.1 - 3e-08 33.1 2.8 5.6e-08 32.2 1.9 1.4 1 0 0 1 1 1 1 Subtilase family Ribosomal_S2 PF00318.15 EDN96005.1 - 4.1e-44 150.3 0.0 4.2e-23 81.6 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EDN96006.1 - 1.9e-06 27.5 0.2 5.2e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 SAE2 PF08573.5 EDN96006.1 - 0.45 11.2 3.7 0.49 11.1 0.4 2.5 2 1 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus vATP-synt_AC39 PF01992.11 EDN96007.1 - 2.5e-117 391.7 0.0 2.8e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EDN96008.1 - 3.5e-54 182.1 2.1 3.5e-54 182.1 1.4 2.3 2 1 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EDN96008.1 - 4.4e-27 93.6 0.1 8.2e-27 92.7 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDN96008.1 - 7.6e-20 70.8 2.5 7.6e-20 70.8 1.7 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ubiquitin PF00240.18 EDN96009.1 - 0.00021 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 EDN96009.1 - 0.014 15.1 23.4 0.02 14.6 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) YukD PF08817.5 EDN96009.1 - 0.033 14.7 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD FAM220 PF15487.1 EDN96009.1 - 1.7 7.9 12.1 0.032 13.6 3.9 1.3 2 0 0 2 2 2 0 FAM220 family DUF1675 PF07897.6 EDN96009.1 - 3.8 7.3 8.4 5 6.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PIG-H PF10181.4 EDN96010.1 - 1.5e-24 85.4 0.6 2.2e-24 84.8 0.4 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component KxDL PF10241.4 EDN96011.1 - 5.9e-27 93.4 0.4 7.7e-27 93.0 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2125 PF09898.4 EDN96011.1 - 0.026 13.8 0.1 0.032 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) CTP_transf_1 PF01148.15 EDN96013.1 - 1.4e-14 54.3 8.1 2e-14 53.9 5.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DEAD PF00270.24 EDN96015.1 - 4.8e-36 123.7 0.0 1.3e-35 122.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDN96015.1 - 2.8e-19 68.3 0.0 5.8e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDN96015.1 - 3.3e-16 58.8 0.0 8.7e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN96015.1 - 0.0023 17.8 0.5 0.026 14.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EDN96015.1 - 0.044 13.0 5.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EDN96015.1 - 0.098 12.4 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EDN96015.1 - 0.89 9.7 4.4 0.65 10.1 0.2 2.6 2 1 0 2 2 2 0 AAA domain Orbi_VP5 PF00901.12 EDN96015.1 - 4.6 5.3 10.1 6.8 4.7 7.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 MPLKIP PF15502.1 EDN96016.1 - 0.005 17.5 0.6 0.011 16.4 0.4 1.6 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Stimulus_sens_1 PF13756.1 EDN96017.1 - 0.08 13.3 0.1 0.74 10.2 0.0 2.1 2 0 0 2 2 2 0 Stimulus-sensing domain Cir_N PF10197.4 EDN96018.1 - 0.00016 21.6 5.1 0.00016 21.6 3.5 2.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EDN96019.1 - 1.1e-55 187.4 0.0 5.6e-39 133.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDN96019.1 - 3.6e-14 52.4 0.0 8.6e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EDN96019.1 - 2e-12 46.5 0.1 2.8e-10 39.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 EDN96019.1 - 3.8e-10 39.0 0.0 4.6e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 EDN96019.1 - 5e-10 39.6 0.8 0.00083 19.5 0.0 4.3 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.1 EDN96019.1 - 7.2e-10 38.8 0.0 6.5e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDN96019.1 - 3e-09 37.7 0.0 0.0048 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EDN96019.1 - 1e-08 34.5 0.2 0.00036 19.6 0.0 3.0 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDN96019.1 - 1.3e-08 34.9 0.0 2.6e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN96019.1 - 2e-08 34.4 0.1 0.012 15.6 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EDN96019.1 - 5.2e-08 32.7 0.2 0.0022 17.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN96019.1 - 5.5e-08 32.4 0.3 0.0068 16.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EDN96019.1 - 9.1e-08 32.4 0.0 0.0039 17.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EDN96019.1 - 9.5e-08 31.6 0.4 0.016 14.5 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_33 PF13671.1 EDN96019.1 - 2.4e-07 30.7 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDN96019.1 - 3.9e-07 30.2 0.0 0.037 14.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EDN96019.1 - 6.9e-07 28.6 0.2 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EDN96019.1 - 5e-06 25.7 0.1 0.021 13.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 EDN96019.1 - 9.6e-06 25.9 0.2 0.03 14.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EDN96019.1 - 5.9e-05 22.6 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EDN96019.1 - 6.5e-05 22.9 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EDN96019.1 - 0.00011 21.2 0.1 0.054 12.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EDN96019.1 - 0.00015 21.2 2.7 0.65 9.3 0.2 3.4 2 2 1 3 3 3 2 AAA domain PhoH PF02562.11 EDN96019.1 - 0.00019 20.7 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EDN96019.1 - 0.00028 20.6 0.4 27 4.3 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Parvo_NS1 PF01057.12 EDN96019.1 - 0.00031 19.7 0.0 0.51 9.1 0.0 2.4 3 0 0 3 3 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EDN96019.1 - 0.00039 20.0 0.0 0.61 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EDN96019.1 - 0.0004 20.4 0.3 0.88 9.6 0.1 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EDN96019.1 - 0.00049 19.7 1.4 0.81 9.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EDN96019.1 - 0.0005 19.6 0.0 0.81 9.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDN96019.1 - 0.00051 19.7 0.7 0.24 11.0 0.0 3.1 4 0 0 4 4 2 1 NACHT domain UPF0079 PF02367.12 EDN96019.1 - 0.00066 19.3 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EDN96019.1 - 0.0008 18.5 0.7 0.035 13.2 0.1 2.6 2 1 0 2 2 2 1 KaiC AAA_30 PF13604.1 EDN96019.1 - 0.0011 18.6 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EDN96019.1 - 0.0015 17.5 0.1 0.62 8.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 EDN96019.1 - 0.0053 16.2 0.0 2.1 7.7 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EDN96019.1 - 0.0056 16.1 0.1 0.59 9.5 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain KTI12 PF08433.5 EDN96019.1 - 0.0059 15.8 0.0 0.34 10.0 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.7 EDN96019.1 - 0.0091 15.6 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 EDN96019.1 - 0.017 14.9 0.2 3.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EDN96019.1 - 0.04 13.6 0.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 NTPase SKI PF01202.17 EDN96019.1 - 0.041 13.7 0.1 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 EDN96019.1 - 0.047 13.2 0.3 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.14 EDN96019.1 - 0.053 12.9 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EDN96019.1 - 0.099 11.8 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EDN96019.1 - 0.1 11.5 0.1 7.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EDN96019.1 - 0.1 12.8 0.9 6.4 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 EDN96019.1 - 0.15 11.7 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 EDN96019.1 - 0.25 10.8 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PseudoU_synth_1 PF01416.15 EDN96020.1 - 1.2e-34 118.9 0.0 1e-25 90.2 0.0 4.2 3 2 0 3 3 3 2 tRNA pseudouridine synthase Ras PF00071.17 EDN96021.1 - 1.1e-13 50.9 0.0 1.9e-11 43.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN96021.1 - 0.00017 22.0 0.0 0.00031 21.2 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EDN96021.1 - 0.081 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RasGEF PF00617.14 EDN96022.1 - 8.7e-48 162.5 0.0 1.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDN96022.1 - 1.2e-13 50.9 0.3 2.8e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1577 PF07614.6 EDN96025.1 - 0.051 12.4 0.1 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) adh_short PF00106.20 EDN96026.1 - 6.2e-22 78.2 4.2 4.9e-16 59.0 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDN96026.1 - 2.3e-05 24.2 0.0 5.6e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN96026.1 - 0.00031 20.4 4.1 0.045 13.4 0.0 2.2 1 1 1 2 2 2 2 KR domain DUF2069 PF09842.4 EDN96026.1 - 0.083 12.8 1.0 0.2 11.6 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) DUF1776 PF08643.5 EDN96026.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pribosyl_synth PF14572.1 EDN96027.1 - 5.9e-39 133.7 0.8 6e-34 117.3 0.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDN96027.1 - 1.7e-25 89.0 0.0 5.3e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDN96027.1 - 6.8e-10 38.7 0.2 1.6e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain G5 PF07501.7 EDN96027.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 G5 domain AviRa PF11599.3 EDN96027.1 - 0.097 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Glyco_tran_WecB PF03808.8 EDN96027.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family RNA_pol_Rpb4 PF03874.11 EDN96028.1 - 3.6e-25 88.2 0.2 3.6e-25 88.2 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 GatB_Yqey PF02637.13 EDN96028.1 - 0.00043 20.0 0.3 0.00055 19.6 0.2 1.1 1 0 0 1 1 1 1 GatB domain RF-1 PF00472.15 EDN96028.1 - 0.12 12.1 1.2 0.25 11.1 0.4 1.7 1 1 1 2 2 2 0 RF-1 domain Fes1 PF08609.5 EDN96028.1 - 0.44 11.0 4.1 1.4 9.4 0.9 2.4 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 ECH PF00378.15 EDN96029.1 - 2.3e-40 138.2 0.0 3e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ribonuc_L-PSP PF01042.16 EDN96030.1 - 3.2e-39 133.4 0.0 3.5e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ATG_C PF09333.6 EDN96031.1 - 0.0028 17.7 1.2 2.4 8.3 0.1 2.8 2 0 0 2 2 2 2 ATG C terminal domain DUF883 PF05957.8 EDN96031.1 - 2.4 8.6 7.2 1.1 9.7 0.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EDN96031.1 - 8.8 6.7 9.4 1.5e+03 -0.4 6.5 3.0 1 1 0 1 1 1 0 YtxH-like protein GATA PF00320.22 EDN96032.1 - 6e-16 57.4 4.9 1.2e-15 56.5 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EDN96032.1 - 1.7e-14 53.6 0.5 3.6e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EDN96032.1 - 9.5e-10 38.7 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EDN96032.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EDN96032.1 - 1.8e-07 31.0 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EDN96032.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF4428 PF14471.1 EDN96032.1 - 1.3 8.7 6.7 0.21 11.3 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) NblA PF04485.7 EDN96032.1 - 1.9 8.4 4.2 7.3 6.5 0.2 2.4 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA SbcCD_C PF13558.1 EDN96033.1 - 3.3e-11 42.9 0.0 1.3e-10 41.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EDN96033.1 - 7e-07 28.7 36.6 1.7e-05 24.1 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDN96033.1 - 7.6e-07 29.6 56.8 7.6e-07 29.6 39.4 7.9 2 1 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EDN96033.1 - 3.9e-06 27.0 4.1 0.0005 20.1 0.5 4.6 5 2 1 6 6 6 2 AAA domain AAA_13 PF13166.1 EDN96033.1 - 1.2e-05 24.0 129.1 0.0034 15.9 0.0 7.4 2 1 5 7 7 7 4 AAA domain AAA_29 PF13555.1 EDN96033.1 - 0.0013 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN96033.1 - 0.086 12.9 0.1 0.086 12.9 0.1 4.8 5 1 0 5 5 5 0 AAA domain DUF1722 PF08349.6 EDN96033.1 - 0.1 12.4 0.0 0.1 12.4 0.0 5.5 5 1 0 5 5 5 0 Protein of unknown function (DUF1722) AAA_16 PF13191.1 EDN96033.1 - 0.69 9.8 0.0 0.69 9.8 0.0 4.5 3 2 2 5 5 5 0 AAA ATPase domain Bac_small_YrzI PF09501.5 EDN96033.1 - 9.2 6.2 14.0 7.1 6.6 2.8 4.9 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) Fungal_trans PF04082.13 EDN96034.1 - 0.0087 14.9 1.5 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 EDN96035.1 - 5.6e-61 205.9 0.1 6.4e-61 205.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96035.1 - 3.3e-20 72.2 0.0 4.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN96035.1 - 8e-08 32.2 0.0 5.3e-05 23.0 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN96035.1 - 0.0075 15.8 0.3 0.023 14.2 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EDN96035.1 - 0.018 14.0 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EDN96035.1 - 0.054 12.5 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF257 PF03192.8 EDN96035.1 - 0.067 12.4 0.7 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 RNase_P_p30 PF01876.11 EDN96036.1 - 3.6e-17 62.0 0.0 5.6e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF4094 PF13334.1 EDN96036.1 - 1.9 8.9 5.8 1.1 9.6 2.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Pap_E4 PF02711.9 EDN96036.1 - 8.7 7.2 6.1 9 7.1 3.6 1.5 1 1 1 2 2 2 0 E4 protein DUF1295 PF06966.7 EDN96038.1 - 1.3e-58 198.0 0.4 1.7e-58 197.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EDN96038.1 - 7.6e-08 32.2 0.6 7.6e-08 32.2 0.4 2.7 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EDN96038.1 - 3.8e-06 27.0 0.3 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EDN96038.1 - 0.00029 20.8 0.0 0.00029 20.8 0.0 2.9 4 1 1 5 5 5 1 Phospholipid methyltransferase SeleniumBinding PF11524.3 EDN96038.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Selenium binding protein adh_short_C2 PF13561.1 EDN96039.1 - 1.6e-36 126.2 0.2 2e-36 126.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN96039.1 - 2.5e-25 89.3 0.1 3.6e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN96039.1 - 8.1e-11 41.9 0.1 1.9e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EDN96039.1 - 7.4e-06 25.5 0.3 1.6e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN96039.1 - 0.014 14.3 0.3 0.017 14.0 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN96039.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN96039.1 - 0.045 13.5 0.5 0.088 12.6 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EDN96039.1 - 0.073 12.1 0.3 0.34 9.9 0.1 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TFIIS_M PF07500.9 EDN96041.1 - 3.7e-29 101.1 3.0 1.2e-28 99.4 0.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EDN96041.1 - 7.9e-18 63.8 7.4 1.4e-17 62.9 5.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EDN96041.1 - 4.9e-12 45.1 0.9 1.1e-11 44.0 0.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Cytochrome_C554 PF13435.1 EDN96041.1 - 0.0068 16.4 4.9 0.0068 16.4 3.4 2.0 2 0 0 2 2 2 1 Cytochrome c554 and c-prime Borrelia_REV PF03978.8 EDN96041.1 - 0.15 11.8 4.4 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Hus1 PF04005.7 EDN96041.1 - 0.94 8.3 5.2 0.89 8.4 0.9 2.1 2 0 0 2 2 2 0 Hus1-like protein CRA PF06589.6 EDN96041.1 - 2.7 7.2 9.0 5.7 6.2 1.3 2.6 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) GST_N_3 PF13417.1 EDN96042.1 - 4e-10 39.7 0.1 8.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN96042.1 - 7.8e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN96042.1 - 7.6e-09 35.4 0.4 2.9e-08 33.6 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Bul1_N PF04425.7 EDN96044.1 - 8.6e-09 34.4 5.7 1.3e-06 27.2 0.8 3.6 3 1 0 3 3 3 2 Bul1 N terminus Arrestin_N PF00339.24 EDN96044.1 - 1.5e-05 24.8 0.2 5.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EDN96044.1 - 0.00017 20.9 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Scm3 PF10384.4 EDN96047.1 - 6.5e-22 76.7 0.9 6.5e-22 76.7 0.7 2.5 2 0 0 2 2 2 1 Centromere protein Scm3 Myb_DNA-bind_2 PF08914.6 EDN96047.1 - 5.4e-07 29.3 0.2 1.5e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EDN96047.1 - 0.047 14.2 0.7 0.29 11.6 0.0 2.8 2 0 0 2 2 2 0 Rap1, DNA-binding Myb_DNA-binding PF00249.26 EDN96047.1 - 0.064 13.3 0.0 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain APG6 PF04111.7 EDN96048.1 - 2.4e-126 421.0 0.1 3e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3142 PF11340.3 EDN96048.1 - 0.032 13.8 0.1 0.2 11.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3142) DUF4337 PF14235.1 EDN96048.1 - 1.3 8.8 5.3 2.2 8.0 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF904 PF06005.7 EDN96048.1 - 3.5 7.9 11.7 3.2 8.1 5.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CPSF_A PF03178.10 EDN96050.1 - 3.8e-88 295.6 0.0 6.1e-86 288.4 0.0 2.8 3 0 0 3 3 3 2 CPSF A subunit region LMBR1 PF04791.11 EDN96051.1 - 2.4e-17 62.6 3.7 2.4e-17 62.6 2.6 2.4 1 1 0 2 2 2 2 LMBR1-like membrane protein CitG PF01874.11 EDN96052.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase zf-MYND PF01753.13 EDN96052.1 - 1 9.2 5.3 1.9 8.4 3.7 1.4 1 0 0 1 1 1 0 MYND finger DUF3807 PF12720.2 EDN96053.1 - 1e-46 159.2 6.5 1.2e-46 158.9 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Nop53 PF07767.6 EDN96053.1 - 0.0021 17.1 7.1 0.0027 16.7 5.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.7 EDN96053.1 - 0.079 12.9 2.7 0.1 12.5 1.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PGA2 PF07543.7 EDN96053.1 - 0.26 11.1 5.2 0.41 10.4 2.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 AbiH PF14253.1 EDN96054.1 - 0.014 14.9 1.7 0.018 14.6 1.2 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Ribosomal_S30 PF04758.9 EDN96054.1 - 0.069 12.9 0.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S30 DUF1041 PF06292.12 EDN96054.1 - 0.5 10.5 2.3 0.27 11.3 0.2 1.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1041) Atg14 PF10186.4 EDN96055.1 - 2.1e-86 289.6 0.0 2.8e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CytochromB561_N PF09786.4 EDN96056.1 - 0.021 13.2 2.6 0.028 12.8 1.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 EDN96056.1 - 0.62 8.2 11.2 0.82 7.8 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2051 PF09738.4 EDN96056.1 - 0.97 8.6 3.7 1.4 8.1 2.6 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF2401 PF10287.4 EDN96057.1 - 2.1e-88 295.8 0.1 3.3e-88 295.1 0.1 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EDN96057.1 - 1.1e-26 92.6 0.8 2.8e-26 91.4 0.1 2.1 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) HTH_Tnp_IS1 PF12759.2 EDN96057.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain NmrA PF05368.8 EDN96059.1 - 9.6e-59 198.4 0.0 1.3e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN96059.1 - 2.5e-14 53.7 0.2 3.6e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN96059.1 - 4.3e-06 25.6 0.0 7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EDN96059.1 - 0.0012 17.8 0.1 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EDN96059.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Peroxin-13_N PF04088.8 EDN96060.1 - 1.7e-59 200.2 0.3 2.6e-59 199.6 0.2 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 EDN96060.1 - 1.2e-07 31.0 0.0 2.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDN96060.1 - 2e-07 30.3 0.0 3.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EDN96060.1 - 6.4e-07 28.8 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Sporozoite_P67 PF05642.6 EDN96060.1 - 0.012 13.4 2.1 0.021 12.6 1.5 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF2733 PF10813.3 EDN96062.1 - 0.33 10.5 0.1 0.33 10.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2733) Histidinol_dh PF00815.15 EDN96063.1 - 7.1e-178 591.4 2.7 7.1e-178 591.4 1.9 1.7 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EDN96063.1 - 4.3e-26 90.3 0.1 7.9e-26 89.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EDN96063.1 - 3.1e-10 40.1 1.8 1.5e-09 37.9 0.1 2.7 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EDN96063.1 - 0.068 13.1 0.7 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain TFIID-31kDa PF02291.10 EDN96064.1 - 2.1e-29 101.8 0.0 8.1e-29 100.0 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF607 PF04678.8 EDN96065.1 - 3.8e-42 144.2 0.2 3.8e-42 144.2 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF607 Rotavirus_VP7 PF05868.6 EDN96066.1 - 0.0016 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 Acetyltransf_8 PF13523.1 EDN96067.1 - 4.2e-45 153.3 0.1 5.1e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Imm38 PF15599.1 EDN96070.1 - 0.079 12.4 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 38 DUF1024 PF06260.7 EDN96074.1 - 0.062 13.4 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) PRKCSH PF07915.8 EDN96077.1 - 3.7e-21 75.7 0.4 1e-20 74.2 0.3 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EDN96077.1 - 0.02 14.3 0.1 0.084 12.3 0.1 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DDE_1 PF03184.14 EDN96079.1 - 1.6e-50 171.2 0.5 4.9e-50 169.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN96079.1 - 4.3e-09 35.7 0.1 9.1e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN96079.1 - 8.4e-08 31.9 0.0 4.4e-07 29.6 0.0 2.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN96079.1 - 1.1e-07 31.6 0.0 2.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EDN96079.1 - 0.037 14.1 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix zf-CCHC PF00098.18 EDN96079.1 - 0.11 12.5 5.1 0.2 11.6 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle ATXN-1_C PF12547.3 EDN96079.1 - 0.12 12.3 1.7 0.34 10.8 1.2 1.8 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator HTH_24 PF13412.1 EDN96079.1 - 0.24 10.8 1.2 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding zf-CCHC_4 PF14392.1 EDN96079.1 - 0.37 10.4 3.4 0.9 9.2 2.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Lar_restr_allev PF14354.1 EDN96081.1 - 1.6 9.0 6.9 0.7 10.2 1.3 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar GFA PF04828.9 EDN96082.1 - 1.1e-06 28.4 0.5 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Corona_nucleoca PF00937.13 EDN96082.1 - 0.017 14.1 2.0 0.017 14.1 1.4 1.7 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein FAD_binding_4 PF01565.18 EDN96083.1 - 2.1e-20 72.5 0.1 1.1e-19 70.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Acetyltransf_3 PF13302.1 EDN96087.1 - 2.7e-11 43.8 0.0 7.5e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN96087.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDN96087.1 - 0.044 13.7 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_72 PF03198.9 EDN96088.1 - 5.4e-104 347.5 0.5 7.4e-104 347.1 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EDN96088.1 - 0.00038 19.7 0.3 0.0035 16.5 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EDN96088.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain NIF PF03031.13 EDN96092.1 - 2.1e-39 134.7 0.1 3.2e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pyr_redox_3 PF13738.1 EDN96094.1 - 3.4e-19 69.7 0.0 8.2e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN96094.1 - 4e-10 38.5 0.1 2.9e-07 29.0 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN96094.1 - 1.6e-06 27.2 0.0 0.0001 21.3 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN96094.1 - 0.023 14.6 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NmrA PF05368.8 EDN96095.1 - 1.5e-15 57.1 0.1 1.8e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EDN96095.1 - 0.048 13.0 0.1 0.28 10.5 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pirin PF02678.11 EDN96098.1 - 1.3e-32 111.8 0.0 2.4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EDN96098.1 - 1.3e-21 76.6 0.1 1.9e-20 72.8 0.1 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EDN96098.1 - 5.9e-08 32.0 0.2 0.00084 18.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EDN96098.1 - 0.00026 20.3 0.1 0.051 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Ank_2 PF12796.2 EDN96100.1 - 1.4e-88 291.3 22.3 3.2e-17 62.6 0.2 12.4 5 3 6 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 EDN96100.1 - 4.3e-75 244.0 26.4 1.4e-07 30.9 0.2 21.2 20 2 0 20 20 20 16 Ankyrin repeat Ank_4 PF13637.1 EDN96100.1 - 5.1e-59 195.6 23.3 7.2e-08 32.7 0.0 15.5 10 4 7 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN96100.1 - 4.2e-53 176.1 28.2 4.6e-06 26.7 0.1 17.1 12 5 5 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN96100.1 - 9.4e-52 167.8 32.4 0.00027 20.8 0.1 21.2 23 1 0 23 23 23 14 Ankyrin repeat NACHT PF05729.7 EDN96101.1 - 0.00095 18.8 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Utp12 PF04003.7 EDN96101.1 - 0.097 12.5 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 Dip2/Utp12 Family Amidase PF01425.16 EDN96102.1 - 3.4e-73 246.9 0.1 2e-72 244.4 0.0 2.2 3 0 0 3 3 3 1 Amidase FAD-oxidase_C PF02913.14 EDN96102.1 - 1.1e-56 191.9 0.1 1.6e-56 191.3 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN96102.1 - 2.5e-35 120.9 0.0 4.8e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 EDN96103.1 - 5e-20 71.1 7.6 6.4e-20 70.7 3.5 2.5 2 0 0 2 2 2 1 Clr5 domain Sensor PF13796.1 EDN96103.1 - 0.67 9.5 2.7 1.4 8.5 1.9 1.4 1 0 0 1 1 1 0 Putative sensor Cu_amine_oxid PF01179.15 EDN96105.1 - 3e-151 503.8 0.1 3.6e-151 503.5 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EDN96105.1 - 9.7e-06 25.5 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EDN96105.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain AA_permease_2 PF13520.1 EDN96106.1 - 3e-20 72.1 18.0 2e-13 49.6 0.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN96106.1 - 1.1e-06 27.2 8.8 0.0083 14.5 6.0 2.1 1 1 1 2 2 2 2 Amino acid permease Fungal_trans PF04082.13 EDN96107.1 - 5.1e-13 48.4 0.2 7.5e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4635 PF15466.1 EDN96108.1 - 0.051 12.8 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) AMP-binding PF00501.23 EDN96109.1 - 5.2e-52 176.6 0.1 8.9e-39 133.0 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme LGFP PF08310.6 EDN96110.1 - 1.3e-35 120.7 0.1 1.8e-10 40.2 0.0 4.4 4 0 0 4 4 4 4 LGFP repeat SPRY PF00622.23 EDN96111.1 - 5.4e-06 26.5 0.2 1.5e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 SPRY domain Acyl_transf_3 PF01757.17 EDN96113.1 - 7.7 5.2 10.0 9.9 4.8 6.9 1.1 1 0 0 1 1 1 0 Acyltransferase family Glyco_hydro_16 PF00722.16 EDN96114.1 - 1e-09 37.9 0.1 1.7e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 EDN96115.1 - 1.7e-23 83.6 0.0 2.1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDN96115.1 - 1.4e-21 77.1 1.1 2.1e-21 76.5 0.7 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EDN96115.1 - 0.0038 16.9 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDN96115.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 DNA_pol3_a_NII PF11490.3 EDN96116.1 - 2.5 7.7 11.6 5 6.7 8.0 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Peptidase_S49_N PF08496.5 EDN96116.1 - 9.6 5.9 8.0 19 5.0 5.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_tranf_2_3 PF13641.1 EDN96121.1 - 7.6e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN96121.1 - 1.9e-08 33.7 0.0 5.8e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN96121.1 - 0.00032 20.4 0.0 0.00067 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tic20 PF09685.5 EDN96121.1 - 0.32 11.0 6.1 0.65 9.9 4.2 1.5 1 0 0 1 1 1 0 Tic20-like protein AdoHcyase_NAD PF00670.16 EDN96123.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GWT1 PF06423.7 EDN96124.1 - 2.3e-45 154.0 2.3 6.9e-45 152.4 1.6 1.9 1 0 0 1 1 1 1 GWT1 p53-inducible11 PF14936.1 EDN96124.1 - 0.042 13.7 0.5 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Pkinase PF00069.20 EDN96127.1 - 4.8e-63 212.7 0.0 8.4e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96127.1 - 7.2e-36 123.5 0.0 9.4e-31 106.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN96127.1 - 1.7e-05 23.9 0.1 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDN96127.1 - 0.0018 18.0 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN96127.1 - 0.016 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN96127.1 - 0.049 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Lactamase_B_3 PF13483.1 EDN96128.1 - 0.00051 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EDN96128.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Bac_small_YrzI PF09501.5 EDN96129.1 - 0.14 12.0 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Chitin_bind_3 PF03067.10 EDN96130.1 - 2e-13 50.9 1.6 2.9e-13 50.5 1.1 1.2 1 0 0 1 1 1 1 Chitin binding domain Na_Ca_ex PF01699.19 EDN96131.1 - 1.3e-37 128.4 32.5 5.6e-21 74.6 11.0 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF737 PF05300.6 EDN96131.1 - 0.069 13.1 6.0 0.17 11.8 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Peptidase_S49_N PF08496.5 EDN96131.1 - 1.3 8.8 4.2 3.9 7.2 2.9 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.4 EDN96131.1 - 1.9 7.8 25.0 1.4 8.3 5.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ras PF00071.17 EDN96132.1 - 1.5e-22 79.7 0.0 2.8e-22 78.8 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN96132.1 - 0.023 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein adh_short PF00106.20 EDN96133.1 - 1.8e-23 83.2 0.2 2.5e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN96133.1 - 2.9e-11 43.3 0.1 1.3e-10 41.2 0.1 1.9 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDN96133.1 - 4.5e-09 36.4 0.0 5.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EDN96133.1 - 0.0026 16.5 0.2 0.042 12.5 0.2 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AraC_binding_2 PF14525.1 EDN96133.1 - 0.032 13.8 0.3 0.05 13.1 0.2 1.2 1 0 0 1 1 1 0 AraC-binding-like domain DEAD PF00270.24 EDN96134.1 - 1.1e-25 90.0 0.9 4.7e-25 88.0 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN96134.1 - 2.9e-23 81.5 0.2 1.3e-22 79.4 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN96134.1 - 6.8e-05 22.7 0.0 0.00028 20.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF543 PF04418.7 EDN96135.1 - 5.8e-28 96.6 0.0 6.8e-28 96.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pkr1 PF08636.5 EDN96136.1 - 0.033 14.2 0.3 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 ER protein Pkr1 DUF4017 PF13209.1 EDN96136.1 - 0.086 12.6 1.0 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) G-alpha PF00503.15 EDN96137.1 - 6e-134 446.5 3.7 7.2e-134 446.3 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EDN96137.1 - 3.5e-15 55.6 2.1 2.2e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EDN96137.1 - 0.0013 18.2 0.0 0.0055 16.2 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EDN96137.1 - 0.0014 19.1 0.7 2.5 8.5 0.0 2.9 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EDN96137.1 - 0.0083 15.2 4.4 0.15 11.1 0.1 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EDN96137.1 - 0.011 15.1 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN96137.1 - 0.03 13.7 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EDN96137.1 - 0.06 13.6 1.0 0.086 13.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain Mog1 PF04603.7 EDN96137.1 - 0.082 12.8 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein MMR_HSR1 PF01926.18 EDN96137.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.4 EDN96139.1 - 8.8e-10 38.4 4.4 1.3e-09 37.8 3.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Vpu PF00558.14 EDN96139.1 - 0.046 13.2 1.8 0.1 12.1 1.2 1.5 1 0 0 1 1 1 0 Vpu protein PTCB-BRCT PF12738.2 EDN96140.1 - 3.3e-07 30.0 1.1 7.7e-07 28.8 0.8 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDN96140.1 - 3.9e-07 30.1 0.1 2e-06 27.8 0.1 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IGPS PF00218.16 EDN96141.1 - 6.9e-97 323.4 0.0 3.2e-96 321.2 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EDN96141.1 - 9.7e-52 175.3 0.1 3.4e-49 167.0 0.4 2.7 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EDN96141.1 - 2.3e-48 164.1 0.0 5.4e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDN96141.1 - 0.00071 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EDN96141.1 - 0.001 18.6 0.8 0.064 12.7 0.0 3.3 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EDN96141.1 - 0.0022 17.0 0.1 0.017 14.1 0.0 2.3 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EDN96141.1 - 0.0044 16.3 0.2 0.04 13.1 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.12 EDN96141.1 - 0.23 10.7 2.0 6.2 6.0 0.0 2.8 3 0 0 3 3 3 0 PcrB family Nup188 PF10487.4 EDN96142.1 - 7.7e-36 123.4 0.0 1.9e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.10 EDN96143.1 - 4.9e-21 73.7 2.5 6.4e-21 73.4 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EDN96143.1 - 0.63 9.5 4.5 2.1 7.8 2.7 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.22 EDN96144.1 - 1.4e-36 125.3 0.0 2.3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Mucin PF01456.12 EDN96145.1 - 0.0066 16.2 18.9 0.0066 16.2 13.1 5.6 2 2 2 4 4 4 1 Mucin-like glycoprotein DUF1754 PF08555.5 EDN96146.1 - 5.6e-17 62.1 10.9 9.2e-17 61.4 7.6 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4599 PF15371.1 EDN96146.1 - 0.34 11.0 4.4 2.6 8.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) DDE_1 PF03184.14 EDN96148.1 - 7e-19 67.8 0.8 1.1e-18 67.2 0.6 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN96148.1 - 3.3e-09 36.4 0.0 1.2e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN96148.1 - 0.01 15.5 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 EDN96148.1 - 0.018 15.1 0.2 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain GMC_oxred_C PF05199.8 EDN96152.1 - 0.0029 17.9 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase ADH_N PF08240.7 EDN96153.1 - 2.9e-21 75.2 0.1 4.8e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN96153.1 - 4.9e-10 39.0 0.3 8.7e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN96153.1 - 0.0036 18.2 0.0 0.022 15.6 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AWPM-19 PF05512.6 EDN96153.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AWPM-19-like family NADH_4Fe-4S PF10589.4 EDN96153.1 - 0.48 9.6 3.3 1.1 8.4 2.3 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Lactamase_B PF00753.22 EDN96155.1 - 2.6e-12 46.7 2.8 4e-12 46.1 1.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ADH_N PF08240.7 EDN96156.1 - 8.9e-29 99.4 1.2 1.5e-28 98.7 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN96156.1 - 1e-18 67.1 0.0 2.9e-18 65.6 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EDN96156.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 EDN96156.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Catalase PF00199.14 EDN96157.1 - 1.9e-160 533.7 0.3 2.5e-160 533.3 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN96157.1 - 5.3e-17 61.4 0.0 9.4e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Glyco_hydro_31 PF01055.21 EDN96159.1 - 4.5e-166 553.0 2.1 6.4e-166 552.5 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Cecropin PF00272.14 EDN96162.1 - 0.52 9.9 5.5 2.1 7.9 0.3 2.2 2 0 0 2 2 2 0 Cecropin family DUF4366 PF14283.1 EDN96163.1 - 0.0032 16.9 0.1 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Vma12 PF11712.3 EDN96163.1 - 0.0037 16.9 0.2 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DcuC PF03606.10 EDN96163.1 - 0.029 12.6 0.0 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Dysbindin PF04440.11 EDN96163.1 - 0.14 11.9 2.5 0.18 11.5 0.3 2.0 1 1 1 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) Ribosomal_60s PF00428.14 EDN96163.1 - 4 7.9 13.4 13 6.2 7.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3329 PF11808.3 EDN96166.1 - 0.088 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) Peptidase_S24 PF00717.18 EDN96168.1 - 4.1e-08 32.7 0.0 6.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 EDN96169.1 - 2.5e-41 140.3 0.0 2.9e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN96169.1 - 8.5e-05 22.3 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN96169.1 - 0.012 15.4 0.2 0.013 15.3 0.2 1.4 1 1 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.13 EDN96170.1 - 4.1e-39 134.2 0.0 7.8e-39 133.3 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DEC-1_N PF04625.8 EDN96170.1 - 0.084 11.5 4.5 0.19 10.4 3.1 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Lamp PF01299.12 EDN96170.1 - 4.1 6.4 7.6 7.3 5.6 2.3 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Kinesin PF00225.18 EDN96171.1 - 1.9e-31 108.9 0.0 3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pyr_redox_3 PF13738.1 EDN96172.1 - 6.3e-16 59.0 0.0 1.9e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN96172.1 - 2e-07 29.6 0.1 3.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN96172.1 - 7.4e-07 28.3 0.0 3.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN96172.1 - 5.5e-05 23.1 0.0 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN96172.1 - 0.00088 19.1 0.0 1.5 8.6 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EDN96172.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EDN96172.1 - 0.0063 15.4 0.0 1.5 7.6 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase BTB PF00651.26 EDN96173.1 - 1.2e-07 31.7 0.0 2.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Aldedh PF00171.17 EDN96175.1 - 5.6e-109 364.5 0.0 7.3e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 EDN96176.1 - 0.0051 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AD PF09793.4 EDN96176.1 - 0.053 13.3 0.6 0.2 11.5 0.2 1.9 1 1 1 2 2 2 0 Anticodon-binding domain PKD PF00801.15 EDN96176.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 PKD domain p450 PF00067.17 EDN96177.1 - 6.2e-09 34.8 0.0 7.7e-09 34.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EDN96178.1 - 6.1e-21 74.3 0.3 1.2e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN96178.1 - 0.0066 16.3 0.2 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3808 PF10300.4 EDN96179.1 - 2.2e-119 399.0 0.0 2.9e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EDN96180.1 - 1.4e-23 82.3 16.7 1.9e-23 82.0 11.6 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 EDN96181.1 - 9.7e-155 514.8 2.0 1.1e-154 514.6 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mpv17_PMP22 PF04117.7 EDN96182.1 - 1e-23 82.7 0.1 2.4e-23 81.5 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PROL5-SMR PF15621.1 EDN96183.1 - 0.077 13.4 9.7 0.12 12.7 6.7 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Mito_fiss_reg PF05308.6 EDN96183.1 - 1.7 7.9 7.4 2.2 7.6 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator X PF00739.14 EDN96183.1 - 2.1 8.2 5.7 3 7.7 4.0 1.3 1 0 0 1 1 1 0 Trans-activation protein X zf-C2H2 PF00096.21 EDN96185.1 - 4.9e-13 48.5 23.4 0.016 15.5 2.0 6.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN96185.1 - 1.2e-11 44.1 21.2 0.049 13.9 1.7 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN96185.1 - 1.2e-05 25.3 3.2 1.2e-05 25.3 2.2 5.0 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDN96185.1 - 0.028 14.5 12.5 5.4 7.2 0.0 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Bunya_G2 PF03563.8 EDN96185.1 - 0.31 9.8 4.4 13 4.5 0.1 3.5 3 1 1 4 4 4 0 Bunyavirus glycoprotein G2 zf-met PF12874.2 EDN96185.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDN96185.1 - 3.7 7.5 13.3 0.21 11.5 0.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Transp_cyt_pur PF02133.10 EDN96187.1 - 1.4e-20 73.3 39.2 1.4e-20 73.3 27.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3938 PF13074.1 EDN96187.1 - 5.2 6.9 14.6 2.7 7.8 0.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3938) TPR_11 PF13414.1 EDN96188.1 - 0.0055 16.3 2.8 8.4 6.1 0.1 4.1 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EDN96188.1 - 0.36 11.5 4.2 7.4 7.3 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Amidohydro_4 PF13147.1 EDN96189.1 - 2.4e-20 73.7 1.8 1.4e-18 67.9 0.2 3.1 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EDN96189.1 - 5.7e-15 54.8 0.5 4.4e-11 42.4 0.1 2.8 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EDN96189.1 - 1.1e-10 41.7 1.0 1.9e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EDN96189.1 - 3.1e-06 26.6 1.9 0.0024 17.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidase_5 PF05382.8 EDN96189.1 - 0.028 14.0 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase ChAPs PF09295.5 EDN96191.1 - 1.4e-154 514.6 1.4 2.7e-153 510.4 1.0 2.1 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EDN96191.1 - 5.7e-05 22.6 0.1 0.38 10.4 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EDN96191.1 - 0.00076 19.7 0.0 0.54 10.6 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN96191.1 - 0.0008 19.8 0.1 1.1 10.1 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN96191.1 - 0.0019 17.9 0.0 2.4 8.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat FTCD PF02971.9 EDN96191.1 - 0.0024 17.5 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase domain TPR_8 PF13181.1 EDN96191.1 - 0.005 16.5 0.0 6.8 6.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN96191.1 - 0.014 15.2 0.2 0.063 13.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN96191.1 - 0.037 14.1 0.0 8.5 6.5 0.0 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EDN96191.1 - 0.041 13.5 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDN96191.1 - 0.053 13.4 0.2 6.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2007 PF09413.5 EDN96191.1 - 0.055 13.3 0.0 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) TPR_7 PF13176.1 EDN96191.1 - 0.13 12.1 0.2 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EDN96192.1 - 3.1e-20 72.0 0.7 7.3e-20 70.8 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN96192.1 - 0.00023 20.9 0.1 0.00074 19.3 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cyclin PF08613.6 EDN96197.1 - 3.8e-11 43.5 0.0 6.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDN96197.1 - 0.0028 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRC_subunit PF08624.5 EDN96199.1 - 4.7e-59 198.2 0.1 7.4e-59 197.6 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 EDN96200.1 - 3.2e-71 239.5 0.0 4.2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96200.1 - 1.8e-31 109.1 0.0 2.6e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDN96200.1 - 3.1e-15 56.4 0.3 1.2e-14 54.4 0.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDN96200.1 - 1.8e-09 36.9 0.0 3.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EDN96200.1 - 0.00069 19.4 0.1 0.0073 16.1 0.0 2.5 1 1 0 1 1 1 1 C2 domain APH PF01636.18 EDN96200.1 - 0.0049 16.6 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDN96200.1 - 0.047 13.0 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EDN96200.1 - 0.083 11.9 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mid2 PF04478.7 EDN96202.1 - 0.0087 15.4 0.4 0.021 14.2 0.3 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 EDN96202.1 - 0.0091 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EDN96202.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP_sub_h PF10775.4 EDN96203.1 - 2.8e-27 94.2 0.6 4.4e-27 93.6 0.4 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EDN96203.1 - 0.032 14.1 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 GFO_IDH_MocA PF01408.17 EDN96205.1 - 6.3e-10 39.6 0.0 1.6e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDN96205.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Ank_5 PF13857.1 EDN96206.1 - 1.8e-18 66.1 0.3 2.4e-12 46.6 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.13 EDN96206.1 - 3.5e-16 59.1 0.0 7.7e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EDN96206.1 - 1.7e-12 47.5 0.0 2.1e-08 34.3 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN96206.1 - 8.4e-11 41.0 0.3 0.085 13.1 0.0 5.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EDN96206.1 - 6.6e-10 39.2 0.1 0.00069 20.0 0.0 4.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN96206.1 - 7.2e-07 28.7 3.6 0.0037 17.0 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeat PX PF00787.19 EDN96206.1 - 0.00033 20.4 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 PX domain DIRP PF06584.8 EDN96206.1 - 0.35 10.7 3.9 0.47 10.3 1.3 2.2 1 1 1 2 2 2 0 DIRP Polysacc_deac_1 PF01522.16 EDN96207.1 - 3.2e-21 75.2 0.0 6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EDN96207.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) UPRTase PF14681.1 EDN96210.1 - 1.9e-18 66.4 0.2 2.4e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase HAD PF12710.2 EDN96210.1 - 0.00029 21.0 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.22 EDN96210.1 - 0.073 12.8 0.2 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Phosphoribosyl transferase domain Hydrolase PF00702.21 EDN96210.1 - 0.085 13.2 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA PF00004.24 EDN96211.1 - 9.5e-40 135.8 0.0 1.8e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN96211.1 - 0.00017 21.3 0.1 0.00079 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN96211.1 - 0.00018 21.5 0.1 0.013 15.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EDN96211.1 - 0.00031 19.8 0.0 0.00067 18.7 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDN96211.1 - 0.00043 20.4 0.1 0.019 15.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EDN96211.1 - 0.00076 19.4 0.1 0.009 15.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EDN96211.1 - 0.0049 16.1 0.2 0.045 12.9 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EDN96211.1 - 0.0084 15.2 0.1 0.021 13.9 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDN96211.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDN96211.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDN96211.1 - 0.018 14.7 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EDN96211.1 - 0.024 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EDN96211.1 - 0.038 13.4 1.5 0.28 10.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN96211.1 - 0.049 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN96211.1 - 0.087 13.6 0.1 0.087 13.6 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EDN96211.1 - 0.15 11.6 1.1 0.68 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 EDN96211.1 - 0.15 10.2 0.5 0.21 9.8 0.2 1.3 1 1 0 1 1 1 0 Herpesvirus UL25 family Vfa1 PF08432.5 EDN96211.1 - 3.6 7.5 9.0 6.8 6.6 6.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIB PF00382.14 EDN96212.1 - 1.5e-36 124.0 0.5 4.7e-21 74.3 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EDN96212.1 - 7.9e-12 44.2 2.6 1.7e-11 43.2 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EDN96212.1 - 0.0032 17.3 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_5 PF01022.15 EDN96212.1 - 0.011 15.3 0.0 4 7.1 0.0 3.2 4 0 0 4 4 4 0 Bacterial regulatory protein, arsR family Androgen_recep PF02166.11 EDN96212.1 - 0.018 13.9 1.1 0.028 13.3 0.3 1.6 2 0 0 2 2 2 0 Androgen receptor HTH_Tnp_ISL3 PF13542.1 EDN96212.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MaoC_dehydratas PF01575.14 EDN96213.1 - 4.9e-23 80.8 0.0 1.5e-22 79.2 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EDN96213.1 - 2.3e-08 33.8 0.0 1.9e-05 24.4 0.0 3.1 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase FA_hydroxylase PF04116.8 EDN96216.1 - 3.8e-12 46.6 4.2 3.8e-12 46.6 2.9 2.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4190 PF13828.1 EDN96216.1 - 0.0017 17.8 0.1 0.0075 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4190) CTF_NFI PF00859.13 EDN96217.1 - 0.017 14.9 0.3 0.017 14.9 0.2 1.0 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Abhydrolase_6 PF12697.2 EDN96219.1 - 2.6e-20 73.2 0.3 9.4e-20 71.4 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN96219.1 - 1.6e-08 34.3 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN96219.1 - 5.6e-08 32.6 0.0 8.6e-07 28.7 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN96219.1 - 0.1 11.7 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glutaredoxin PF00462.19 EDN96220.1 - 3.6e-14 52.4 0.0 8.2e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin MFS_1 PF07690.11 EDN96221.1 - 3.4e-39 134.5 34.6 3.4e-39 134.5 24.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PhyH PF05721.8 EDN96222.1 - 0.89 9.5 4.2 0.9 9.5 2.9 1.0 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DDRGK PF09756.4 EDN96222.1 - 7.3 5.9 18.0 7.5 5.9 12.5 1.0 1 0 0 1 1 1 0 DDRGK domain DUF3899 PF13038.1 EDN96222.1 - 9.5 6.4 6.7 10 6.3 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Ribosom_S12_S23 PF00164.20 EDN96224.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S12/S23 p450 PF00067.17 EDN96225.1 - 7.6e-06 24.7 0.1 2.6e-05 22.9 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 CryBP1 PF07029.6 EDN96225.1 - 0.0048 16.6 0.0 0.0067 16.1 0.0 1.1 1 0 0 1 1 1 1 CryBP1 protein DUF4294 PF14127.1 EDN96225.1 - 0.025 14.1 0.2 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) SNF5 PF04855.7 EDN96226.1 - 1.2e-85 286.9 0.0 1.7e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EDN96226.1 - 1.4e-05 24.2 4.8 3e-05 23.2 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAT1 PF09770.4 EDN96227.1 - 0.25 9.5 90.3 0.064 11.4 29.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Proteasom_Rpn13 PF04683.8 EDN96228.1 - 2.4e-27 94.8 0.0 3.4e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EDN96229.1 - 1.3e-38 131.5 0.2 1.3e-38 131.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.10 EDN96230.1 - 5e-220 731.2 0.0 6e-220 730.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 EDN96230.1 - 0.13 12.1 2.0 0.31 10.9 1.4 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain RVT_1 PF00078.22 EDN96231.1 - 5.1e-24 84.8 0.1 9.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN96231.1 - 2.7e-17 63.0 0.3 8.9e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EDN96231.1 - 0.00021 20.6 0.0 0.00045 19.5 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVP_2 PF08284.6 EDN96231.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN96231.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ribosomal_L6 PF00347.18 EDN96232.1 - 3e-25 88.5 6.1 3.2e-13 49.9 0.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Sulfate_transp PF00916.15 EDN96234.1 - 1.8e-34 119.0 6.0 3.5e-34 118.0 4.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EDN96234.1 - 2.5e-17 62.4 0.0 4.5e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EDN96234.1 - 1.4e-10 40.6 0.0 2.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain ACT_7 PF13840.1 EDN96234.1 - 0.076 12.5 0.5 0.51 9.8 0.1 2.5 2 0 0 2 2 2 0 ACT domain Sld5 PF05916.6 EDN96235.1 - 2e-13 50.5 0.0 3.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.14 EDN96236.1 - 4e-11 43.0 0.2 4e-11 43.0 0.2 3.1 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN96236.1 - 0.00088 19.5 0.2 0.00088 19.5 0.2 2.7 2 0 0 2 2 2 1 HMG-box domain DUF3328 PF11807.3 EDN96240.1 - 8.9e-22 77.8 1.9 1e-21 77.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aldedh PF00171.17 EDN96241.1 - 5.4e-132 440.4 0.2 6.4e-132 440.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDN96241.1 - 0.0017 17.5 0.0 0.004 16.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Neuromodulin PF06614.6 EDN96241.1 - 0.29 11.0 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Neuromodulin MFS_1 PF07690.11 EDN96242.1 - 6.2e-19 67.9 38.3 3e-15 55.7 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDN96242.1 - 2.1e-08 32.8 10.2 2.6e-08 32.5 7.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ion_trans PF00520.26 EDN96244.1 - 2.4e-86 288.1 82.0 2.7e-34 118.1 7.2 5.6 5 1 0 5 5 5 4 Ion transport protein DUF3824 PF12868.2 EDN96244.1 - 0.015 16.2 0.6 0.015 16.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) EF-hand_1 PF00036.27 EDN96244.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 EF hand FPN1 PF06963.7 EDN96247.1 - 1.8e-83 280.3 17.0 4.5e-44 150.5 1.7 3.1 3 0 0 3 3 3 3 Ferroportin1 (FPN1) HTH_psq PF05225.11 EDN96249.1 - 3.3e-10 39.3 0.4 2e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN96249.1 - 1.9e-07 30.8 0.1 5.8e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN96249.1 - 2.4e-06 26.8 0.2 0.0017 17.5 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_36 PF13730.1 EDN96249.1 - 0.0025 17.9 0.2 0.12 12.4 0.1 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain NUMOD1 PF07453.8 EDN96249.1 - 0.019 14.8 0.4 0.06 13.2 0.3 1.9 1 0 0 1 1 1 0 NUMOD1 domain bZIP_1 PF00170.16 EDN96249.1 - 0.053 13.4 1.3 0.053 13.4 0.9 2.5 3 0 0 3 3 3 0 bZIP transcription factor DUF2962 PF11176.3 EDN96249.1 - 0.053 13.0 4.0 0.14 11.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2962) DUF2668 PF10873.3 EDN96251.1 - 0.53 10.4 13.7 0.064 13.4 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Syndecan PF01034.15 EDN96251.1 - 0.63 9.7 2.2 1.6 8.4 1.6 1.6 1 0 0 1 1 1 0 Syndecan domain TPR_12 PF13424.1 EDN96252.1 - 2.3e-12 46.6 0.1 2e-08 34.0 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDN96252.1 - 2.1e-10 40.1 0.0 1.1e-08 34.7 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN96252.1 - 0.012 16.1 0.5 0.13 12.9 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN96252.1 - 0.043 14.1 0.1 0.32 11.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Latarcin PF10279.4 EDN96252.1 - 0.048 13.8 3.1 0.089 12.9 0.7 2.3 2 1 0 2 2 2 0 Latarcin precursor DinB_2 PF12867.2 EDN96252.1 - 0.055 13.8 0.1 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 DinB superfamily RuvA_C PF07499.8 EDN96252.1 - 0.062 13.4 0.0 0.87 9.8 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_11 PF13414.1 EDN96252.1 - 0.065 12.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 TPR repeat AAA_16 PF13191.1 EDN96253.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 EDN96253.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 EDN96253.1 - 0.084 13.0 0.1 0.26 11.4 0.0 1.8 1 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDN96253.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase p450 PF00067.17 EDN96254.1 - 2.2e-06 26.4 0.0 4.2e-06 25.5 0.0 1.3 2 0 0 2 2 2 1 Cytochrome P450 TRAM_LAG1_CLN8 PF03798.11 EDN96255.1 - 2e-29 102.5 14.4 2.8e-29 102.0 10.0 1.2 1 0 0 1 1 1 1 TLC domain DUF1282 PF06930.7 EDN96255.1 - 0.0054 16.4 1.7 0.012 15.3 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) TRAP_alpha PF03896.11 EDN96255.1 - 0.071 12.0 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PHD PF00628.24 EDN96257.1 - 9.9e-09 34.7 7.8 1.9e-08 33.8 5.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN96257.1 - 0.013 14.7 3.9 0.029 13.6 2.7 1.5 1 0 0 1 1 1 0 PHD-finger PRCH PF03967.8 EDN96257.1 - 0.11 12.0 0.3 0.42 10.1 0.2 1.9 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Tim54 PF11711.3 EDN96260.1 - 3.6e-136 453.7 0.0 4.4e-136 453.4 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 P_C PF06640.6 EDN96260.1 - 0.97 9.3 8.2 0.22 11.4 3.1 1.8 2 0 0 2 2 2 0 P protein C-terminus NARP1 PF12569.3 EDN96261.1 - 6.3e-208 691.7 31.2 6.7e-207 688.3 15.5 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EDN96261.1 - 7.8e-23 80.6 24.2 4.4e-05 23.7 0.0 7.4 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 EDN96261.1 - 5.1e-21 74.0 25.9 2.9e-06 26.8 0.3 7.7 7 1 0 7 7 7 4 TPR repeat TPR_14 PF13428.1 EDN96261.1 - 3.3e-18 64.5 13.6 0.0011 19.4 0.1 9.3 7 3 4 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN96261.1 - 1.5e-17 63.7 26.2 0.0012 19.4 0.0 6.9 7 1 0 7 7 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDN96261.1 - 9.5e-16 56.6 10.5 0.00074 19.5 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDN96261.1 - 5.3e-15 54.0 31.4 0.00025 20.6 0.2 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN96261.1 - 2.5e-11 43.3 19.3 0.033 14.1 0.3 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN96261.1 - 4e-10 38.7 14.7 0.011 15.4 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN96261.1 - 6.5e-10 38.1 33.0 3.1e-05 23.3 0.4 9.0 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN96261.1 - 4.4e-08 32.8 8.1 0.0012 18.6 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN96261.1 - 3.5e-05 23.2 12.9 2.3 8.2 0.1 6.9 5 1 1 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDN96261.1 - 0.0011 18.7 15.7 4.6 7.1 0.3 5.6 5 1 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EDN96261.1 - 0.0033 17.7 7.5 0.47 11.0 1.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 EDN96261.1 - 0.024 14.9 0.2 0.024 14.9 0.1 2.7 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EDN96261.1 - 0.049 13.5 17.0 8.4 6.4 0.4 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin PF00637.15 EDN96261.1 - 0.065 12.8 9.5 0.68 9.5 0.0 4.5 5 0 0 5 5 5 0 Region in Clathrin and VPS TPR_3 PF07720.7 EDN96261.1 - 0.17 11.7 9.0 0.19 11.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN96261.1 - 0.3 11.6 38.2 0.69 10.5 0.2 9.4 11 0 0 11 11 9 0 Tetratricopeptide repeat Sel1 PF08238.7 EDN96261.1 - 0.37 11.4 5.4 0.21 12.2 0.3 3.1 3 0 0 3 3 3 0 Sel1 repeat NAM-associated PF14303.1 EDN96261.1 - 0.81 9.9 19.5 0.069 13.4 0.3 3.1 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF3366 PF11846.3 EDN96261.1 - 1.7 8.5 10.8 0.58 10.0 0.1 4.0 3 1 1 5 5 5 0 Domain of unknown function (DUF3366) Cid2 PF09774.4 EDN96262.1 - 2e-49 167.5 0.0 2.5e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Dymeclin PF09742.4 EDN96262.1 - 0.1 10.6 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Mito_carr PF00153.22 EDN96263.1 - 3.6e-46 154.8 4.8 3.6e-17 61.8 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 EDN96265.1 - 5e-09 35.9 0.1 1.2e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.12 EDN96266.1 - 2.4e-136 452.9 0.1 2.7e-136 452.7 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EDN96266.1 - 1.5e-82 275.2 2.7 2.3e-82 274.6 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDN96266.1 - 2.1e-06 27.0 0.6 3.8e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EDN96266.1 - 0.0058 16.2 0.9 0.015 14.8 0.4 1.6 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EDN96266.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein IlvN PF07991.7 EDN96266.1 - 0.044 13.1 0.3 0.078 12.3 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EDN96266.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ATG11 PF10377.4 EDN96267.1 - 9.2e-41 138.7 0.0 9.2e-41 138.7 0.0 3.7 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.7 EDN96267.1 - 0.00034 19.5 0.9 0.00034 19.5 0.6 6.6 3 3 3 6 6 6 1 Autophagy protein Apg17 Filament PF00038.16 EDN96267.1 - 0.0041 16.6 33.7 0.0041 16.6 23.4 4.9 2 1 1 3 3 3 2 Intermediate filament protein IncA PF04156.9 EDN96267.1 - 4.1 6.9 87.4 1.1 8.8 6.8 6.7 3 1 3 6 6 6 0 IncA protein CENP-H PF05837.7 EDN96268.1 - 2.6e-32 111.1 13.1 2.7e-32 111.1 3.6 2.6 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Period_C PF12114.3 EDN96268.1 - 0.025 14.1 2.2 0.052 13.1 0.7 1.8 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Tmemb_18A PF09771.4 EDN96268.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Fusion_gly PF00523.13 EDN96268.1 - 0.046 11.7 0.6 0.059 11.4 0.4 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Terminase_2 PF03592.11 EDN96268.1 - 0.094 12.9 0.3 0.094 12.9 0.2 2.2 1 1 1 2 2 2 0 Terminase small subunit IncA PF04156.9 EDN96268.1 - 7.9 6.0 11.6 1.6 8.2 3.6 2.1 1 1 1 2 2 2 0 IncA protein Pkinase PF00069.20 EDN96269.1 - 5.1e-56 189.7 0.1 9.7e-55 185.5 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96269.1 - 8.6e-27 93.8 0.2 6.9e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN96269.1 - 7.6e-05 21.8 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Med15 PF09606.5 EDN96269.1 - 8e-05 21.0 48.0 9.9e-05 20.7 33.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Kdo PF06293.9 EDN96269.1 - 0.00047 19.2 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN96269.1 - 0.00095 18.9 3.5 0.016 14.9 0.2 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDN96269.1 - 0.037 12.8 0.1 0.06 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EDN96269.1 - 0.05 12.4 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EDN96269.1 - 0.16 11.3 2.1 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 EDN96270.1 - 2e-05 24.6 0.6 3.7e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EDN96270.1 - 0.027 14.0 0.4 0.041 13.4 0.2 1.2 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EDN96270.1 - 0.05 12.8 0.9 0.094 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.20 EDN96271.1 - 1.2e-14 53.7 0.1 2.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EDN96271.1 - 4.8e-08 32.4 22.2 0.0038 16.7 1.7 4.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN96271.1 - 1.4e-07 31.1 16.9 0.0066 16.1 1.5 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EDN96271.1 - 1.9e-05 24.2 15.9 6.3 7.1 0.0 7.3 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.28 EDN96271.1 - 0.0026 17.5 13.4 7.9 6.9 0.1 6.7 7 1 0 7 7 7 1 Leucine Rich Repeat BetaGal_dom3 PF13363.1 EDN96271.1 - 0.12 11.7 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 LRR_7 PF13504.1 EDN96271.1 - 0.16 12.2 9.6 14 6.4 0.2 6.2 7 0 0 7 7 7 0 Leucine rich repeat Feld-I_B PF09252.5 EDN96272.1 - 0.044 13.6 0.2 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain zf-H2C2_2 PF13465.1 EDN96273.1 - 4.1e-08 33.1 8.3 2e-07 30.9 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDN96273.1 - 2e-06 27.8 5.0 0.0001 22.3 0.1 3.5 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN96273.1 - 7.8e-06 25.8 2.8 0.00086 19.4 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN96273.1 - 0.053 13.6 1.9 4.4 7.5 0.2 3.1 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Aldo_ket_red PF00248.16 EDN96274.1 - 1.9e-55 187.7 0.0 2.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3185 PF11381.3 EDN96275.1 - 0.019 14.7 1.8 0.02 14.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SoxE PF06525.6 EDN96275.1 - 0.055 12.7 0.9 0.076 12.2 0.6 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF2569 PF10754.4 EDN96275.1 - 6.1 7.0 6.8 4.3 7.5 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Fe_hyd_lg_C PF02906.9 EDN96276.1 - 7.8e-67 225.5 0.0 1.6e-66 224.5 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2413 PF10310.4 EDN96278.1 - 5.4 5.7 7.1 6.3 5.5 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDE_1 PF03184.14 EDN96282.1 - 8.9e-16 57.6 0.2 1e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EDN96283.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN96283.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN96283.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN96283.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN96283.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle PAP2 PF01569.16 EDN96284.1 - 5.7e-22 77.7 0.7 1.9e-21 76.0 0.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily SieB PF14163.1 EDN96284.1 - 0.18 11.3 0.1 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Abhydrolase_6 PF12697.2 EDN96285.1 - 1.7e-22 80.4 0.2 2.1e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN96285.1 - 1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN96285.1 - 6.4e-06 25.8 0.1 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EDN96285.1 - 0.073 11.5 0.0 0.092 11.2 0.0 1.3 1 1 0 1 1 1 0 Ndr family MCC-bdg_PDZ PF10506.4 EDN96287.1 - 0.092 12.5 0.2 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Hydrophobin_2 PF06766.6 EDN96288.1 - 3.4e-23 81.0 9.2 4.2e-23 80.8 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_53 PF07745.8 EDN96290.1 - 1.6e-81 273.6 0.0 2e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 NAD_binding_4 PF07993.7 EDN96291.1 - 8.3e-33 113.3 0.0 1.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN96291.1 - 4.2e-24 84.7 0.0 7.7e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EDN96291.1 - 1.8e-09 37.3 0.0 5.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN96291.1 - 1.9e-09 37.6 0.1 5.5e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EDN96291.1 - 0.039 13.6 0.0 0.15 11.7 0.0 2.0 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 EDN96291.1 - 0.047 13.6 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EDN96291.1 - 0.079 11.6 0.0 0.14 10.8 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN96291.1 - 0.2 10.5 0.0 0.45 9.3 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein XH PF03469.9 EDN96292.1 - 0.034 13.7 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 XH domain ketoacyl-synt PF00109.21 EDN96294.1 - 3.4e-12 46.3 0.0 3.7e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDN96295.1 - 1.8e-05 24.2 0.1 2.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain MFS_1 PF07690.11 EDN96296.1 - 0.003 16.3 21.8 0.0064 15.2 14.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3246 PF11596.3 EDN96297.1 - 0.0079 15.5 0.1 0.0096 15.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Tachykinin PF02202.11 EDN96297.1 - 0.1 12.3 0.2 0.3 10.8 0.1 1.9 1 0 0 1 1 1 0 Tachykinin family Amidoligase_2 PF12224.3 EDN96301.1 - 1.1e-47 162.7 0.0 1.8e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF1388 PF07142.7 EDN96302.1 - 5.6e-09 35.5 3.0 6.1e-09 35.4 0.6 2.0 2 0 0 2 2 2 1 Repeat of unknown function (DUF1388) Synaphin PF05835.7 EDN96302.1 - 4.2 7.5 17.6 7.5 6.7 12.2 1.4 1 0 0 1 1 1 0 Synaphin protein Pectate_lyase_3 PF12708.2 EDN96303.1 - 1.2e-75 254.4 22.1 8.3e-64 215.7 3.3 3.4 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EDN96303.1 - 4.6e-07 29.2 0.6 0.0025 17.2 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Sulfate_transp PF00916.15 EDN96305.1 - 5.4e-42 143.7 13.4 5.4e-42 143.7 9.3 2.3 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDN96305.1 - 6.9e-27 92.9 3.2 6.9e-27 92.9 2.2 3.1 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDN96305.1 - 4.1e-10 39.0 0.0 8.7e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain BCS1_N PF08740.6 EDN96306.1 - 2.6e-44 151.1 0.0 3.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN96306.1 - 2.7e-16 59.9 0.0 5.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN96306.1 - 3.8e-06 27.7 0.1 1e-05 26.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDN96306.1 - 9.1e-05 21.9 0.0 0.00031 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN96306.1 - 0.00072 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN96306.1 - 0.001 19.1 0.1 0.015 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN96306.1 - 0.0019 18.3 0.0 0.0062 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN96306.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EDN96306.1 - 0.0084 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN96306.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EDN96306.1 - 0.017 14.6 0.1 0.048 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDN96306.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EDN96306.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EDN96306.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EDN96306.1 - 0.03 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN96306.1 - 0.031 14.0 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EDN96306.1 - 0.037 12.9 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EDN96306.1 - 0.042 13.8 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN96306.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EDN96306.1 - 0.065 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EDN96306.1 - 0.09 12.4 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 1 0 NACHT domain Arch_ATPase PF01637.13 EDN96306.1 - 0.1 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 EDN96306.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EDN96306.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Mg_chelatase PF01078.16 EDN96306.1 - 0.14 11.3 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EDN96306.1 - 0.19 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lum_binding PF00677.12 EDN96308.1 - 4.5e-39 132.2 2.0 2.4e-22 78.6 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain Abhydrolase_1 PF00561.15 EDN96310.1 - 4.9e-17 62.2 0.1 2.9e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EDN96310.1 - 1.6e-13 50.3 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EDN96310.1 - 4.8e-10 39.7 0.7 4.3e-09 36.5 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN96310.1 - 4.5e-05 23.2 1.2 0.002 17.9 0.8 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_72 PF03198.9 EDN96312.1 - 1.7e-96 322.9 0.1 2.1e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase EF-hand_1 PF00036.27 EDN96314.1 - 1.1e-37 124.3 11.8 1.1e-08 33.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDN96314.1 - 8.2e-35 118.7 2.8 1.9e-16 59.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EDN96314.1 - 2.5e-34 116.6 12.8 4.1e-14 51.9 0.6 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EDN96314.1 - 8.8e-31 103.0 3.9 4.7e-08 32.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDN96314.1 - 1.6e-28 96.7 8.1 2.1e-07 29.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EDN96314.1 - 3.8e-13 49.1 0.1 3.2e-06 26.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EDN96314.1 - 8.7e-09 35.4 0.0 0.0047 16.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EDN96314.1 - 5e-07 29.4 2.8 0.00092 18.9 0.1 2.6 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EDN96314.1 - 2.7e-06 26.8 0.1 0.063 12.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EDN96314.1 - 1.5e-05 24.6 0.0 0.0047 16.4 0.0 2.3 1 1 0 1 1 1 1 Caleosin related protein TerB PF05099.8 EDN96314.1 - 5.4e-05 22.9 0.2 0.17 11.6 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.3 EDN96314.1 - 0.00046 20.5 0.0 0.056 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) DUF3164 PF11363.3 EDN96314.1 - 0.00086 18.7 0.2 0.32 10.3 0.1 3.3 1 1 3 4 4 4 1 Protein of unknown function (DUF3164) Acetyltransf_11 PF13720.1 EDN96314.1 - 0.0013 18.9 0.0 0.073 13.3 0.0 2.3 2 0 0 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RNA_pol_Rpb4 PF03874.11 EDN96314.1 - 0.012 15.6 1.2 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 EF-hand_10 PF14788.1 EDN96314.1 - 0.035 13.7 5.5 0.14 11.8 0.2 3.8 2 2 2 4 4 4 0 EF hand PMBR PF09373.5 EDN96314.1 - 0.042 13.8 0.2 30 4.8 0.0 4.2 4 0 0 4 4 4 0 Pseudomurein-binding repeat DUF3335 PF11814.3 EDN96314.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C39 like family SpoVIF PF14069.1 EDN96314.1 - 0.088 12.5 1.2 7.8 6.3 0.1 2.7 2 1 0 2 2 2 0 Stage VI sporulation protein F DUF3647 PF12363.3 EDN96314.1 - 0.12 12.5 2.0 6.4 6.9 0.1 2.5 2 1 1 3 3 3 0 Phage protein YqeY PF09424.5 EDN96314.1 - 0.14 12.0 0.8 1.5 8.6 0.6 2.1 1 1 1 2 2 2 0 Yqey-like protein HU-DNA_bdg PF14848.1 EDN96314.1 - 0.14 11.8 0.6 5.8 6.6 0.0 2.6 1 1 2 3 3 3 0 DNA-binding domain DUF1456 PF07308.8 EDN96314.1 - 0.15 12.0 0.2 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF1296 PF06972.6 EDN96314.1 - 0.23 11.4 1.6 15 5.6 0.1 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF1296) Amidoligase_2 PF12224.3 EDN96315.1 - 6.1e-14 52.2 0.0 5.7e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Putative amidoligase enzyme DUF3987 PF13148.1 EDN96320.1 - 0.032 12.8 6.4 0.041 12.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4043 PF13252.1 EDN96320.1 - 0.077 11.9 0.2 0.095 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Cut8_N PF14482.1 EDN96320.1 - 0.6 10.1 0.1 0.6 10.1 0.1 3.5 3 1 0 3 3 3 0 Cut8 proteasome-binding domain Adeno_terminal PF02459.10 EDN96321.1 - 0.074 11.2 0.6 0.11 10.6 0.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PTCB-BRCT PF12738.2 EDN96323.1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.4 1 1 1 2 2 2 1 twin BRCT domain FAD_binding_3 PF01494.14 EDN96325.1 - 2.3e-13 49.9 0.1 0.0011 18.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EDN96325.1 - 0.00045 20.1 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN96325.1 - 0.008 15.1 0.0 0.056 12.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN96325.1 - 0.013 15.8 0.2 0.034 14.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1087 PF06465.8 EDN96328.1 - 0.076 12.9 0.4 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF3742 PF12553.3 EDN96334.1 - 0.22 11.9 1.8 1.6 9.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) DUF2306 PF10067.4 EDN96335.1 - 3.8e-12 46.2 6.8 3.8e-12 46.2 4.7 2.0 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) PepSY_TM_1 PF13172.1 EDN96335.1 - 0.063 13.0 0.2 0.063 13.0 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Glyco_hydro_cc PF11790.3 EDN96336.1 - 2.8e-65 220.0 2.5 4.5e-65 219.4 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Rad51 PF08423.6 EDN96337.1 - 1.5e-25 89.5 0.0 2.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDN96337.1 - 2.5e-09 36.8 0.0 4.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDN96337.1 - 4.4e-06 25.9 0.1 2.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDN96337.1 - 1.1e-05 24.6 0.1 3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EDN96337.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EDN96337.1 - 0.06 12.2 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.13 EDN96337.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MFS_1 PF07690.11 EDN96338.1 - 1.6e-42 145.4 14.8 1.6e-42 145.4 10.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EDN96338.1 - 0.00014 20.1 9.7 0.00029 19.0 2.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector PUCC PF03209.10 EDN96338.1 - 0.00051 18.8 6.3 0.00086 18.1 1.3 2.3 2 0 0 2 2 2 1 PUCC protein DUF3043 PF11241.3 EDN96338.1 - 0.0011 18.5 0.9 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3043) Mem_trans PF03547.13 EDN96338.1 - 0.0023 16.3 0.3 0.0039 15.5 0.2 1.5 1 0 0 1 1 1 1 Membrane transport protein OATP PF03137.15 EDN96338.1 - 0.061 11.3 3.4 0.71 7.8 1.5 2.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ASFV_J13L PF05568.6 EDN96338.1 - 0.18 11.3 0.6 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein AMP-binding PF00501.23 EDN96339.1 - 5.1e-80 268.9 0.2 1.5e-42 145.4 0.0 3.5 2 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EDN96339.1 - 6.6e-73 245.1 0.3 6e-39 133.6 0.0 2.3 2 0 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.7 EDN96339.1 - 3e-34 118.0 0.0 5.6e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EDN96339.1 - 3.3e-16 59.2 0.1 4e-10 39.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDN96339.1 - 1.8e-11 44.8 0.0 0.00016 22.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EDN96340.1 - 1.1e-70 237.8 0.0 1.5e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96340.1 - 9.9e-49 165.7 0.0 1.9e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN96340.1 - 1.3e-05 24.3 0.0 5.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Transglut_core PF01841.14 EDN96342.1 - 9.4e-12 45.1 0.0 2.5e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily RVT_1 PF00078.22 EDN96343.1 - 1.8e-15 56.9 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PG_binding_3 PF09374.5 EDN96343.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 1 0 1 1 1 0 Predicted Peptidoglycan domain RNase_H PF00075.19 EDN96344.1 - 4.5e-12 46.4 0.0 8.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.11 EDN96345.1 - 1.6e-32 112.5 31.4 1.6e-32 112.5 21.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 EDN96346.1 - 7.3e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.11 EDN96347.1 - 3.1e-89 298.3 0.0 7.9e-89 297.0 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 EDN96347.1 - 1.8e-76 256.0 0.1 1.1e-75 253.4 0.0 1.9 2 0 0 2 2 2 1 Hexokinase MiAMP1 PF09117.5 EDN96347.1 - 0.074 13.4 0.2 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 MiAMP1 FGGY_N PF00370.16 EDN96347.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ribophorin_I PF04597.9 EDN96348.1 - 4.6e-153 509.7 0.4 5.2e-153 509.6 0.3 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.5 EDN96349.1 - 3.8e-100 334.5 0.6 6.5e-100 333.7 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EDN96349.1 - 7.7e-25 88.2 11.9 2.2e-22 80.1 6.9 3.6 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EDN96349.1 - 6e-12 45.6 2.3 1.3e-11 44.5 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Amidohydro_1 PF01979.15 EDN96350.1 - 2.8e-33 115.9 0.0 3.6e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EDN96350.1 - 5.6e-10 39.0 0.0 6.1e-06 25.6 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EDN96350.1 - 6.8e-07 29.5 0.1 0.016 15.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EDN96350.1 - 1.4e-05 24.8 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EDN96350.1 - 0.0023 16.9 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Lipase_GDSL_2 PF13472.1 EDN96351.1 - 5.8e-15 55.8 0.0 1.5e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN96351.1 - 3.8e-07 30.1 0.0 7.2e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MCM PF00493.18 EDN96352.1 - 3.9e-132 440.0 0.0 8.4e-132 438.9 0.0 1.5 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN96352.1 - 6.9e-25 87.8 0.0 4.1e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN96352.1 - 9.3e-06 24.9 0.0 0.00034 19.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN96352.1 - 6.8e-05 22.6 0.0 0.00026 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN96352.1 - 0.00072 19.1 0.0 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MazG-like PF12643.2 EDN96352.1 - 0.03 14.2 0.4 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 MazG-like family Sigma54_activat PF00158.21 EDN96352.1 - 0.1 12.0 0.1 4.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_32 PF13654.1 EDN96352.1 - 0.27 9.8 5.1 0.035 12.7 0.5 1.6 2 0 0 2 2 2 0 AAA domain RVT_thumb PF06817.9 EDN96353.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Clat_adaptor_s PF01217.15 EDN96356.1 - 0.0016 18.2 0.1 0.0098 15.6 0.0 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 EDN96357.1 - 5.4e-55 185.3 0.0 9.5e-55 184.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EDN96357.1 - 6e-28 97.4 0.0 2.9e-27 95.2 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding HTH_Tnp_Tc5 PF03221.11 EDN96358.1 - 2.3e-09 36.9 0.0 4.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN96358.1 - 0.00011 21.3 0.1 0.00058 19.0 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_1 PF03184.14 EDN96359.1 - 1e-06 28.0 0.1 1.2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ArsD PF06953.6 EDN96359.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD Response_reg PF00072.19 EDN96362.1 - 2.4e-15 56.5 0.0 5.2e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDN96362.1 - 1.2e-11 44.4 0.0 2.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 EDN96362.1 - 5.2e-08 32.6 0.0 2.9e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EDN96362.1 - 0.041 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 GAF domain DUF823 PF05689.6 EDN96362.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Proteasome PF00227.21 EDN96363.1 - 1.1e-48 165.0 0.4 1.3e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1590 PF07629.6 EDN96366.1 - 0.1 12.2 0.1 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) tRNA-synt_1b PF00579.20 EDN96368.1 - 1e-59 202.0 0.0 1.3e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ApoO PF09769.4 EDN96369.1 - 2e-49 167.3 0.5 2.5e-48 163.7 0.0 2.0 2 0 0 2 2 2 2 Apolipoprotein O Peptidase_M3 PF01432.15 EDN96370.1 - 9.1e-121 404.0 0.0 1.3e-120 403.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EDN96370.1 - 0.014 14.7 0.1 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like WSC PF01822.14 EDN96371.1 - 6.8e-21 73.9 7.2 1.2e-20 73.2 5.0 1.4 1 0 0 1 1 1 1 WSC domain p450 PF00067.17 EDN96372.1 - 6e-46 156.9 0.0 4.5e-43 147.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 IMS PF00817.15 EDN96373.1 - 1.5e-39 135.1 0.0 3.2e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDN96373.1 - 1.9e-17 63.3 0.0 4.7e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EDN96373.1 - 2.7e-15 56.1 9.8 7.7e-07 29.0 0.4 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EDN96373.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDN96373.1 - 0.00023 20.9 0.1 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EDN96373.1 - 0.00096 19.0 0.2 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 EDN96373.1 - 0.011 15.8 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain MgtE_N PF03448.12 EDN96373.1 - 0.072 13.4 1.0 9.5 6.6 0.0 3.5 3 0 0 3 3 3 0 MgtE intracellular N domain MFS_1 PF07690.11 EDN96374.1 - 3.5e-33 114.7 39.9 9.4e-30 103.4 8.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily SecY PF00344.15 EDN96374.1 - 0.22 10.4 9.1 0.67 8.8 0.1 2.9 3 0 0 3 3 3 0 SecY translocase OATP PF03137.15 EDN96374.1 - 1.5 6.7 8.3 0.047 11.7 0.7 2.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EDN96374.1 - 1.7 7.1 22.9 1.2 7.5 0.1 3.2 2 1 0 3 3 3 0 Sugar (and other) transporter Sugar_tr PF00083.19 EDN96376.1 - 3.9e-94 315.7 34.7 4.8e-94 315.4 24.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN96376.1 - 3.7e-22 78.5 42.2 1.2e-19 70.2 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3353 PF11833.3 EDN96376.1 - 3.6 6.9 9.0 0.41 10.0 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) DnaJ PF00226.26 EDN96377.1 - 9.6e-16 57.2 2.0 1.6e-15 56.6 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain TMEMspv1-c74-12 PF11044.3 EDN96377.1 - 0.77 9.3 1.8 1.4 8.5 1.2 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein p450 PF00067.17 EDN96378.1 - 2.6e-18 65.8 0.0 6e-18 64.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Metallophos_2 PF12850.2 EDN96379.1 - 2.8e-12 46.7 0.0 5.9e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EDN96379.1 - 3.9e-10 39.4 0.6 4.3e-09 36.0 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Caldesmon PF02029.10 EDN96380.1 - 0.015 13.7 0.6 0.03 12.7 0.0 1.6 2 0 0 2 2 2 0 Caldesmon TP2 PF01254.13 EDN96380.1 - 0.024 14.9 0.2 0.041 14.2 0.2 1.3 1 0 0 1 1 1 0 Nuclear transition protein 2 bZIP_2 PF07716.10 EDN96381.1 - 0.083 12.7 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF3425 PF11905.3 EDN96382.1 - 3.4e-30 104.7 0.2 6.1e-30 103.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDN96382.1 - 0.0095 15.8 3.3 0.018 15.0 2.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor ATG22 PF11700.3 EDN96383.1 - 4.1e-183 609.2 22.0 4.6e-183 609.0 15.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EDN96383.1 - 2.2 6.9 52.6 0.16 10.6 5.0 3.8 2 1 1 3 3 3 0 Major Facilitator Superfamily Pkinase PF00069.20 EDN96385.1 - 6.3e-09 35.3 0.0 9.3e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96385.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDN96385.1 - 0.16 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family LCM PF04072.9 EDN96387.1 - 3.7e-22 78.7 0.0 5.2e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DSPc PF00782.15 EDN96388.1 - 6.8e-08 32.1 0.0 7.5e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EDN96388.1 - 0.0095 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase End3 PF12761.2 EDN96389.1 - 4.5e-75 251.5 0.1 6.1e-75 251.1 0.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EDN96389.1 - 4.5e-50 167.7 0.0 1e-49 166.5 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EDN96389.1 - 2.4e-07 29.5 0.3 6.6e-07 28.1 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EDN96389.1 - 6e-07 28.9 0.2 3.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EDN96389.1 - 3.4e-05 23.8 0.7 0.00011 22.2 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN96389.1 - 0.0018 17.9 1.2 0.0038 16.9 0.2 2.1 2 0 0 2 2 1 1 EF-hand domain EF-hand_5 PF13202.1 EDN96389.1 - 0.0073 15.5 1.4 0.013 14.8 0.1 2.1 2 0 0 2 2 2 1 EF hand TPR_MLP1_2 PF07926.7 EDN96389.1 - 0.012 15.3 1.7 0.41 10.4 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 EDN96389.1 - 0.047 13.5 4.0 0.052 13.4 0.4 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EDN96389.1 - 0.053 13.2 3.5 0.044 13.5 0.9 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ALIX_LYPXL_bnd PF13949.1 EDN96389.1 - 0.076 11.9 5.2 0.16 10.9 3.6 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mnd1 PF03962.10 EDN96389.1 - 0.4 10.3 4.2 0.98 9.0 2.9 1.6 1 1 0 1 1 1 0 Mnd1 family SlyX PF04102.7 EDN96389.1 - 0.64 10.4 3.9 15 6.0 0.8 2.7 2 0 0 2 2 2 0 SlyX TSC22 PF01166.13 EDN96389.1 - 3.4 7.6 7.4 12 5.9 1.3 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family SNF2_N PF00176.18 EDN96391.1 - 3.6e-68 229.5 0.4 3.6e-68 229.5 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN96391.1 - 5.9e-16 58.1 0.0 1.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN96391.1 - 1.1e-05 25.2 2.4 1.9e-05 24.5 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EDN96391.1 - 0.0026 16.6 0.2 0.02 13.7 0.0 2.5 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EDN96391.1 - 0.05 13.7 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Myb_DNA-bind_4 PF13837.1 EDN96392.1 - 3.9e-07 30.1 5.3 8.2e-05 22.6 0.3 2.9 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Homeobox PF00046.24 EDN96392.1 - 0.00061 19.3 0.3 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 1 Homeobox domain Myb_DNA-bind_5 PF13873.1 EDN96392.1 - 0.0024 17.6 2.8 0.017 14.9 0.1 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN96392.1 - 0.018 15.0 1.6 10 6.2 0.1 3.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Homeobox PF00046.24 EDN96394.1 - 0.00022 20.7 0.1 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Myb_DNA-bind_4 PF13837.1 EDN96396.1 - 0.0027 17.8 0.4 0.006 16.6 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EDN96396.1 - 0.007 16.2 2.0 0.016 15.0 0.1 2.4 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN96396.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN96396.1 - 0.028 14.4 0.9 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain RhoGAP PF00620.22 EDN96397.1 - 2.3e-45 153.8 0.1 6.9e-45 152.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain DUF948 PF06103.6 EDN96397.1 - 9.2 6.2 6.3 29 4.6 0.9 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CLASP_N PF12348.3 EDN96400.1 - 4.4e-135 448.2 1.4 1.7e-90 302.3 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EDN96400.1 - 0.00029 20.6 0.1 16 5.9 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 EDN96400.1 - 0.011 15.9 0.4 6.6 7.0 0.0 4.9 4 2 0 4 4 4 0 HEAT repeats DUF2115 PF09888.4 EDN96400.1 - 0.085 12.9 0.2 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) BSP PF04450.7 EDN96401.1 - 1.2e-80 269.7 0.0 1.5e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EDN96401.1 - 3.2e-07 30.4 0.2 2.2e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 EDN96401.1 - 0.0025 17.4 0.5 0.0044 16.6 0.4 1.4 1 0 0 1 1 1 1 SprT-like family Lectin_C PF00059.16 EDN96404.1 - 0.059 14.0 4.2 0.36 11.4 1.4 2.4 2 0 0 2 2 2 0 Lectin C-type domain Sec62 PF03839.11 EDN96405.1 - 4.6e-49 166.8 0.0 4.6e-49 166.8 0.0 2.4 2 1 0 2 2 2 1 Translocation protein Sec62 RHH_4 PF13467.1 EDN96405.1 - 3.7e-05 23.5 4.3 0.58 10.0 0.0 3.4 2 1 1 3 3 3 3 Ribbon-helix-helix domain RHH_1 PF01402.16 EDN96405.1 - 0.023 14.5 0.0 25 4.9 0.0 3.4 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF3713 PF12506.3 EDN96405.1 - 0.14 12.2 1.8 2.4 8.2 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF768 PF05589.6 EDN96405.1 - 0.26 11.2 3.5 14 5.6 0.1 3.3 2 2 1 4 4 4 0 Protein of unknown function (DUF768) DUF4023 PF13215.1 EDN96405.1 - 0.32 10.7 12.1 0.96 9.2 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4023) DUF1848 PF08902.6 EDN96405.1 - 0.6 9.6 4.4 0.91 9.0 2.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) DUF3349 PF11829.3 EDN96405.1 - 1.3 9.5 6.1 3.1 8.2 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) HA PF03457.9 EDN96405.1 - 4.3 7.5 10.1 1.8 8.7 0.0 3.2 1 1 1 2 2 2 0 Helicase associated domain DUF3595 PF12166.3 EDN96405.1 - 4.7 5.9 6.7 9.9 4.8 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF3431 PF11913.3 EDN96406.1 - 1e-61 208.2 0.5 1.5e-61 207.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Gliadin PF13016.1 EDN96406.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Cys-rich Gliadin N-terminal RRM_6 PF14259.1 EDN96407.1 - 1.6e-10 40.8 0.1 5.9e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN96407.1 - 4.4e-10 39.2 0.0 9.2e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EDN96407.1 - 5.7e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EDN96407.1 - 4.6e-06 26.1 0.1 4.2e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN96407.1 - 0.00011 21.8 0.0 0.0053 16.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EDN96407.1 - 0.015 14.9 4.1 0.025 14.2 2.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EDN96407.1 - 1.2 9.0 11.1 0.66 9.8 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Glyco_hydro_92 PF07971.7 EDN96408.1 - 1.9e-154 515.0 1.5 2.5e-154 514.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 SNF2_N PF00176.18 EDN96411.1 - 2.2e-71 240.0 0.0 3.3e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN96411.1 - 1.9e-11 43.6 0.0 3.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN96411.1 - 1.8e-07 30.8 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EDN96411.1 - 1.4e-05 24.7 2.8 2.7e-05 23.8 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN96411.1 - 0.0067 16.0 1.5 0.023 14.3 1.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN96411.1 - 0.016 14.8 2.0 0.036 13.7 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN96411.1 - 0.02 14.6 2.7 0.042 13.6 1.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EDN96411.1 - 0.022 14.7 0.9 0.049 13.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Brucella_OMP2 PF05244.6 EDN96411.1 - 0.12 11.5 0.1 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Sgf11 PF08209.6 EDN96411.1 - 0.4 10.0 2.5 4 6.8 0.1 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) PI3_PI4_kinase PF00454.22 EDN96412.1 - 1.1e-41 142.8 0.0 1.6e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase YqeY PF09424.5 EDN96413.1 - 2.2e-23 82.7 5.8 2.6e-23 82.4 4.0 1.1 1 0 0 1 1 1 1 Yqey-like protein RE_MjaI PF09568.5 EDN96413.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF3104 PF11302.3 EDN96414.1 - 0.14 11.5 0.9 0.18 11.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3104) GTP_EFTU PF00009.22 EDN96415.1 - 9e-62 207.8 0.1 1.4e-61 207.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDN96415.1 - 9.5e-22 76.6 0.0 3.9e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EDN96415.1 - 9.1e-12 44.6 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDN96415.1 - 1.6e-11 44.1 2.3 4.5e-11 42.7 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EDN96415.1 - 3.2e-07 29.9 0.0 1.1e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EDN96415.1 - 2.9e-05 23.9 0.1 5.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EDN96415.1 - 0.1 12.0 0.1 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Solute_trans_a PF03619.11 EDN96417.1 - 4.2e-91 305.0 4.4 5.5e-91 304.6 3.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Methyltransf_11 PF08241.7 EDN96420.1 - 8.5e-05 22.9 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EDN96420.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.11 EDN96420.1 - 0.00028 19.3 0.0 0.00032 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 EDN96420.1 - 0.00049 19.8 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN96420.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain NOGCT PF08155.6 EDN96421.1 - 2.1e-29 100.9 4.6 4.6e-29 99.8 3.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EDN96421.1 - 3.5e-27 94.0 0.9 8.6e-27 92.7 0.6 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EDN96421.1 - 8.9e-15 54.6 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN96421.1 - 2.1e-08 33.5 0.0 4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDN96421.1 - 0.0002 21.8 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EDN96421.1 - 0.0045 16.1 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EDN96421.1 - 0.011 15.5 0.1 4.6 7.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Pribosyltran PF00156.22 EDN96422.1 - 1.8e-16 59.9 1.1 3e-16 59.2 0.8 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3984 PF13136.1 EDN96423.1 - 0.078 12.1 0.3 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Asp_protease PF09668.5 EDN96424.1 - 8e-63 209.5 0.3 1.2e-62 208.9 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EDN96424.1 - 3.4e-12 45.5 0.3 6.8e-12 44.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.1 EDN96424.1 - 4.7e-12 46.2 0.0 1.4e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 EDN96424.1 - 3.1e-07 30.0 0.0 7.5e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EDN96424.1 - 4.2e-07 29.9 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN96424.1 - 2e-06 27.4 0.0 5.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 EDN96424.1 - 0.0001 21.9 0.2 0.0002 20.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 EDN96424.1 - 0.00024 20.9 0.0 0.00092 19.0 0.0 2.0 2 1 0 2 2 1 1 Retroviral aspartyl protease YukD PF08817.5 EDN96424.1 - 0.00036 21.0 0.1 0.0008 19.9 0.1 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.3 EDN96424.1 - 0.00036 20.7 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RuvA_C PF07499.8 EDN96424.1 - 0.022 14.8 0.1 0.055 13.6 0.0 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain AlkA_N PF06029.6 EDN96424.1 - 0.023 14.7 0.5 0.048 13.7 0.3 1.5 1 0 0 1 1 1 0 AlkA N-terminal domain DUF2407 PF10302.4 EDN96424.1 - 0.023 14.8 0.1 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBA_4 PF14555.1 EDN96424.1 - 0.08 12.4 0.6 0.21 11.1 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain Methyltransf_8 PF05148.10 EDN96425.1 - 3e-57 193.7 0.0 3.8e-54 183.6 0.0 2.7 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EDN96425.1 - 1.8e-06 28.3 0.9 1.2e-05 25.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN96425.1 - 0.00024 20.7 0.2 0.37 10.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EDN96425.1 - 0.036 13.4 0.4 4.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EDN96425.1 - 0.042 13.5 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EDN96427.1 - 5e-16 58.2 2.8 3.1e-14 52.3 1.1 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN96427.1 - 7.4e-07 28.9 11.7 1.4e-06 28.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bcl-2_3 PF15286.1 EDN96428.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Mg_trans_NIPA PF05653.9 EDN96430.1 - 1.6e-92 309.7 26.8 2.2e-92 309.2 18.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EDN96430.1 - 2.2e-07 31.0 6.8 2.2e-07 31.0 4.7 3.4 1 1 2 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EDN96430.1 - 2.6e-06 27.4 7.0 2.6e-06 27.4 4.8 3.3 3 1 1 4 4 4 1 EamA-like transporter family DUF1843 PF08898.5 EDN96430.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Nucleoplasmin PF03066.10 EDN96431.1 - 0.34 10.4 5.4 0.29 10.6 3.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin Spore_YtfJ PF09579.5 EDN96431.1 - 0.79 9.6 2.6 1.2 9.0 1.8 1.3 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) CENP-B_dimeris PF09026.5 EDN96431.1 - 7.7 6.8 9.7 10 6.4 6.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LigB PF02900.13 EDN96435.1 - 1.6e-47 161.7 0.0 1.9e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF321 PF03778.8 EDN96438.1 - 0.21 11.0 1.2 2.3 7.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Pentapeptide_4 PF13599.1 EDN96439.1 - 0.0007 19.3 0.1 0.00096 18.9 0.1 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Mpv17_PMP22 PF04117.7 EDN96440.1 - 1.7e-21 75.5 0.2 3e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1360 PF07098.6 EDN96442.1 - 0.012 15.3 0.1 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) DUF3445 PF11927.3 EDN96444.1 - 1.7e-73 247.0 0.0 2.3e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Gar1 PF04410.9 EDN96445.1 - 3.9e-48 162.8 0.5 3.9e-48 162.8 0.4 2.5 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 EDN96446.1 - 5e-84 282.7 18.3 5.9e-84 282.4 12.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CBM_1 PF00734.13 EDN96447.1 - 3.3e-07 29.8 9.5 3.3e-07 29.8 6.6 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain adh_short PF00106.20 EDN96448.1 - 3.8e-18 65.9 0.0 4.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN96448.1 - 1.7e-09 37.5 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN96448.1 - 0.14 10.9 0.0 0.35 9.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PNP_UDP_1 PF01048.15 EDN96449.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily Exo5 PF09810.4 EDN96450.1 - 5e-119 397.2 0.1 6.2e-119 396.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EDN96450.1 - 2.8e-10 40.0 0.8 2.2e-09 37.0 0.6 2.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PsbJ PF01788.12 EDN96451.1 - 0.094 12.2 2.0 0.16 11.5 1.4 1.3 1 0 0 1 1 1 0 PsbJ DUF1996 PF09362.5 EDN96452.1 - 6e-81 271.5 0.1 8.2e-81 271.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EDN96452.1 - 3.4e-19 68.5 8.9 3.4e-19 68.5 6.2 2.5 2 0 0 2 2 2 1 WSC domain PAS_9 PF13426.1 EDN96453.1 - 1.1e-16 61.0 0.0 1e-13 51.5 0.0 2.7 2 1 0 2 2 2 2 PAS domain RGS PF00615.14 EDN96453.1 - 3.6e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.19 EDN96453.1 - 0.0074 16.0 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EDN96453.1 - 0.1 12.6 0.0 17 5.4 0.0 2.6 2 0 0 2 2 2 0 PAS fold FAD_binding_3 PF01494.14 EDN96454.1 - 6e-28 97.9 0.0 8.5e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN96454.1 - 7.2e-07 28.4 1.8 0.021 13.7 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN96454.1 - 0.0023 16.9 0.5 2.1 7.1 0.2 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDN96454.1 - 0.0054 15.6 0.2 0.018 13.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EDN96454.1 - 0.0098 15.9 0.1 0.027 14.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN96454.1 - 0.011 15.5 0.4 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN96454.1 - 0.028 13.0 0.2 12 4.4 0.1 3.0 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.5 EDN96454.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Abhydrolase_5 PF12695.2 EDN96456.1 - 9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN96456.1 - 2e-10 40.9 0.2 3.9e-10 39.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EDN96456.1 - 4.3e-10 38.7 0.0 5.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EDN96456.1 - 1.3e-05 24.5 0.0 2.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EDN96456.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EDN96456.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EDN96456.1 - 0.092 12.2 0.4 2.5 7.5 0.1 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Ndr PF03096.9 EDN96456.1 - 0.22 9.9 0.0 0.36 9.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.13 EDN96460.1 - 0.00014 20.8 1.0 0.00037 19.4 0.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Alginate_lyase2 PF08787.6 EDN96463.1 - 2.4e-51 174.6 0.0 2.8e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Cys_rich_CWC PF14375.1 EDN96464.1 - 0.081 12.8 0.6 0.12 12.3 0.4 1.3 1 1 0 1 1 1 0 Cysteine-rich CWC HDA2-3 PF11496.3 EDN96467.1 - 7.2e-08 31.5 2.7 7.9e-08 31.4 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EDN96467.1 - 0.00039 20.0 0.6 0.00088 18.9 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PSD2 PF07624.6 EDN96467.1 - 0.021 14.4 0.1 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) APG6 PF04111.7 EDN96467.1 - 0.87 8.5 31.2 1.3 8.0 11.1 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 EDN96467.1 - 1.3 8.5 25.5 0.025 14.1 5.8 3.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SAB PF04382.8 EDN96467.1 - 2.9 7.6 10.4 4.5 7.0 0.1 3.7 4 0 0 4 4 4 0 SAB domain Peptidase_C48 PF02902.14 EDN96468.1 - 6.9e-27 94.4 0.0 2.1e-26 92.9 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain COX5A PF02284.11 EDN96470.1 - 1e-40 138.0 0.3 1.4e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.8 EDN96470.1 - 0.028 14.7 0.3 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF488 DHC_N1 PF08385.7 EDN96470.1 - 0.045 12.1 0.2 0.85 7.9 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ELO PF01151.13 EDN96471.1 - 5e-64 215.9 17.1 5.9e-64 215.7 11.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RPE65 PF03055.10 EDN96471.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein Ribosomal_L4 PF00573.17 EDN96475.1 - 3.1e-40 137.6 0.1 4.2e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EDN96475.1 - 2.5e-25 88.1 0.4 5.5e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain EamA PF00892.15 EDN96475.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 EamA-like transporter family Ribosomal_S8e PF01201.17 EDN96479.1 - 1.4e-28 99.6 0.2 2.1e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Abhydrolase_6 PF12697.2 EDN96480.1 - 3.8e-10 40.0 0.0 4.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN96480.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN96480.1 - 0.0042 16.8 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mt_ATP-synt_B PF05405.9 EDN96481.1 - 3.6e-50 169.6 7.8 4.4e-50 169.3 5.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Orthopox_A5L PF06193.6 EDN96481.1 - 0.022 14.7 1.3 0.036 14.0 0.1 1.9 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like Dak2 PF02734.12 EDN96481.1 - 0.033 13.8 1.1 0.072 12.7 0.4 1.8 1 1 1 2 2 2 0 DAK2 domain SRX PF09201.5 EDN96481.1 - 0.057 13.0 0.9 0.1 12.2 0.7 1.4 1 0 0 1 1 1 0 SRX DUF1539 PF07560.6 EDN96481.1 - 0.087 12.6 1.3 0.15 11.9 0.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) CBF PF03914.12 EDN96482.1 - 1.2e-48 164.6 0.1 2.1e-48 163.8 0.1 1.4 1 0 0 1 1 1 1 CBF/Mak21 family Utp12 PF04003.7 EDN96482.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 1 0 1 1 1 0 Dip2/Utp12 Family Sel1 PF08238.7 EDN96483.1 - 2.5e-10 40.6 4.5 9.1e-07 29.3 0.0 3.6 4 0 0 4 4 4 2 Sel1 repeat bZIP_Maf PF03131.12 EDN96485.1 - 1.3e-06 28.5 12.6 4.6e-06 26.8 8.7 1.9 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EDN96485.1 - 2e-06 27.4 10.0 6e-06 25.9 6.9 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN96485.1 - 2.9e-06 27.1 10.1 2.9e-06 27.1 7.0 2.5 1 1 1 2 2 2 1 bZIP transcription factor AAA_23 PF13476.1 EDN96485.1 - 0.068 13.4 4.5 0.13 12.5 3.1 1.4 1 0 0 1 1 1 0 AAA domain Endotoxin_N PF03945.9 EDN96485.1 - 0.22 10.8 4.2 0.41 10.0 2.9 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain zf-CCCH PF00642.19 EDN96489.1 - 0.37 10.5 15.7 1.1 9.0 1.3 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 EDN96490.1 - 3.8e-85 286.0 0.2 4.3e-85 285.8 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit SpoIIE PF07228.7 EDN96491.1 - 4.7e-12 46.0 0.4 5.6e-11 42.5 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EDN96491.1 - 3.5e-06 26.6 0.1 0.015 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDN96491.1 - 3.7e-06 26.5 0.3 8.9e-06 25.2 0.2 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4341 PF14241.1 EDN96491.1 - 0.042 13.5 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) Glyco_transf_17 PF04724.8 EDN96492.1 - 1.4e-26 93.3 0.0 2.9e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 Glyco_hydro_16 PF00722.16 EDN96496.1 - 4.9e-10 39.0 1.3 3.9e-09 36.0 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.27 EDN96497.1 - 9.5e-53 174.3 19.3 9.7e-10 37.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EDN96497.1 - 3e-15 55.1 3.2 6.1e-15 54.1 2.2 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EDN96497.1 - 0.011 15.4 0.0 0.42 10.2 0.0 2.9 3 1 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A TMEM171 PF15471.1 EDN96499.1 - 3.5 6.3 10.4 2.2 7.0 1.4 2.4 2 0 0 2 2 2 0 Transmembrane protein family 171 PAN_3 PF08277.7 EDN96501.1 - 0.00038 20.0 2.9 0.029 13.9 0.1 2.6 2 0 0 2 2 2 2 PAN-like domain PAN_1 PF00024.21 EDN96502.1 - 1.6e-14 53.4 24.8 9.2e-06 25.3 0.6 3.6 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.7 EDN96502.1 - 3.3e-06 26.6 8.5 0.041 13.5 0.1 3.4 3 0 0 3 3 3 3 PAN-like domain PAN_4 PF14295.1 EDN96502.1 - 3.8e-06 26.4 21.0 0.0022 17.6 0.4 4.3 4 0 0 4 4 4 3 PAN domain Glyco_transf_34 PF05637.7 EDN96503.1 - 3.8e-64 216.4 0.2 5.2e-64 216.0 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family HSCB_C PF07743.8 EDN96505.1 - 5.9e-18 65.0 3.1 1.1e-17 64.2 1.2 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EDN96505.1 - 4.2e-09 36.0 0.0 7.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Halo_GVPC PF05465.8 EDN96505.1 - 0.021 14.7 1.1 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat HTH_29 PF13551.1 EDN96506.1 - 8e-06 25.9 0.2 2.1e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EDN96506.1 - 7e-05 23.5 1.0 0.00015 22.4 0.7 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 EDN96506.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Arg_repressor PF01316.16 EDN96506.1 - 0.072 12.6 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Pkinase PF00069.20 EDN96507.1 - 6.9e-48 163.0 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96507.1 - 4.4e-21 75.1 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN96507.1 - 7.2e-07 28.4 0.0 2.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN96507.1 - 0.00056 19.7 0.0 0.33 10.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EDN96507.1 - 0.0035 16.6 0.4 0.0084 15.4 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Lipase_GDSL_2 PF13472.1 EDN96508.1 - 1.2e-19 71.1 0.0 1.3e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN96508.1 - 7.5e-05 22.6 0.4 0.002 17.9 0.3 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.22 EDN96509.1 - 4.1e-14 52.7 0.1 2e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EDN96509.1 - 4.1e-05 23.0 0.2 8.7e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 MS_channel PF00924.13 EDN96511.1 - 1.1e-26 93.5 3.9 1.9e-26 92.7 2.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EDN96511.1 - 0.0019 17.3 0.2 0.0051 16.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN96511.1 - 0.0021 18.1 0.5 0.0072 16.4 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN96511.1 - 0.011 15.5 0.6 0.043 13.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.1 EDN96511.1 - 0.035 13.4 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 EF hand FR47 PF08445.5 EDN96511.1 - 0.061 13.0 0.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 FR47-like protein BLOC1_2 PF10046.4 EDN96511.1 - 0.71 10.0 3.1 5.7 7.1 0.1 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Beta_elim_lyase PF01212.16 EDN96512.1 - 8.7e-73 244.9 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EDN96512.1 - 1.5e-05 23.5 0.0 2.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDN96512.1 - 0.003 16.6 0.6 0.022 13.7 0.4 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EDN96512.1 - 0.017 13.8 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDN96512.1 - 0.033 13.1 0.0 0.068 12.1 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class I and II GTP_cyclohydro2 PF00925.15 EDN96512.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 GTP cyclohydrolase II HTH_psq PF05225.11 EDN96513.1 - 1.2e-09 37.6 0.1 2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN96513.1 - 3.8e-07 29.8 0.3 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN96513.1 - 2.4e-05 23.6 0.5 8.7e-05 21.7 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease DUF3404 PF11884.3 EDN96513.1 - 0.015 14.1 0.1 0.027 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HTH_28 PF13518.1 EDN96513.1 - 0.037 14.0 0.5 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDN96513.1 - 0.038 13.8 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 NUMOD1 domain HTH_29 PF13551.1 EDN96513.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.1 EDN96513.1 - 0.096 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EDN96513.1 - 0.099 12.3 0.5 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain AAA PF00004.24 EDN96515.1 - 1.5e-52 177.2 0.0 4e-43 146.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN96515.1 - 4.2e-06 27.5 0.1 0.0013 19.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN96515.1 - 1.3e-05 24.7 0.5 0.00052 19.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN96515.1 - 6.4e-05 22.1 0.0 0.00044 19.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EDN96515.1 - 0.0001 21.2 0.0 0.00076 18.4 0.0 2.0 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EDN96515.1 - 0.00019 21.5 0.2 0.0063 16.6 0.0 3.2 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN96515.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EDN96515.1 - 0.0012 19.0 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EDN96515.1 - 0.0016 18.4 6.2 0.026 14.5 0.0 4.2 4 1 1 5 5 4 1 AAA ATPase domain AAA_2 PF07724.9 EDN96515.1 - 0.0026 17.6 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EDN96515.1 - 0.0046 15.7 0.0 0.0087 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EDN96515.1 - 0.011 15.4 2.4 0.026 14.2 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain Mg_chelatase PF01078.16 EDN96515.1 - 0.014 14.5 0.1 0.04 13.0 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN96515.1 - 0.021 14.5 0.0 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EDN96515.1 - 0.023 13.9 0.0 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EDN96515.1 - 0.028 13.5 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EDN96515.1 - 0.029 14.6 0.0 0.092 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EDN96515.1 - 0.045 13.2 0.0 1.8 8.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 EDN96515.1 - 0.051 13.4 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDN96515.1 - 0.056 13.3 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EDN96515.1 - 0.25 9.9 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NB-ARC PF00931.17 EDN96515.1 - 0.25 10.1 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EDN96515.1 - 1.3 8.5 5.4 0.22 11.0 0.1 2.4 3 0 0 3 3 3 0 AAA domain Abhydro_lipase PF04083.11 EDN96516.1 - 4.7e-20 70.7 0.0 2e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EDN96516.1 - 2.7e-05 24.1 0.0 4.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN96516.1 - 0.0079 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN96516.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3402 PF11882.3 EDN96522.1 - 0.011 14.8 0.6 0.015 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RAMPs PF03787.10 EDN96522.1 - 0.029 14.2 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 RAMP superfamily CHU_C PF13585.1 EDN96522.1 - 0.47 10.3 9.1 0.32 10.8 5.1 1.7 1 1 1 2 2 2 0 C-terminal domain of CHU protein family BAT2_N PF07001.6 EDN96528.1 - 0.006 16.9 0.2 0.0099 16.2 0.1 1.3 1 0 0 1 1 1 1 BAT2 N-terminus Cytochrom_B561 PF03188.11 EDN96531.1 - 1.9 8.2 6.6 4.6 7.0 4.5 1.7 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 FAD_binding_3 PF01494.14 EDN96532.1 - 4e-13 49.1 0.0 1e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN96532.1 - 0.0037 16.2 0.0 0.54 9.1 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN96532.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2172 PF09940.4 EDN96533.1 - 0.13 10.5 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Abhydrolase_2 PF02230.11 EDN96535.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDN96535.1 - 1.2e-06 28.2 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN96535.1 - 9.4e-05 22.3 0.0 0.0037 17.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EDN96535.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF3759 PF12585.3 EDN96537.1 - 4e-36 122.7 4.8 5.4e-36 122.3 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.2 EDN96537.1 - 0.33 11.8 6.1 12 6.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Peptidase_M18 PF02127.10 EDN96538.1 - 6.5e-128 426.8 0.0 8.4e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1360 PF07098.6 EDN96539.1 - 0.067 12.9 0.3 0.067 12.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) DUF485 PF04341.7 EDN96545.1 - 1.2 8.9 4.2 2.4 7.9 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 COesterase PF00135.23 EDN96546.1 - 3.3e-99 333.0 0.0 4.6e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN96546.1 - 7.4e-06 25.6 0.4 0.00013 21.6 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN96546.1 - 0.001 18.3 0.1 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ribosomal_60s PF00428.14 EDN96548.1 - 0.0005 20.4 1.9 0.0005 20.4 1.3 2.4 3 0 0 3 3 3 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EDN96548.1 - 0.0053 16.2 1.5 0.0053 16.2 1.0 2.2 2 1 0 2 2 2 1 Nucleoplasmin FANCL_C PF11793.3 EDN96548.1 - 0.0092 15.9 0.4 0.015 15.2 0.3 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EDN96548.1 - 0.046 13.5 0.5 0.072 12.9 0.3 1.3 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.7 EDN96548.1 - 0.051 12.7 2.1 0.052 12.7 1.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger HSA PF07529.8 EDN96548.1 - 0.15 11.8 1.8 0.4 10.4 0.4 2.1 2 0 0 2 2 2 0 HSA Mak16 PF04874.9 EDN96548.1 - 0.28 11.2 11.0 0.077 13.0 3.3 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region RRP7 PF12923.2 EDN96548.1 - 0.56 10.2 5.6 1.2 9.2 3.9 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Myc_N PF01056.13 EDN96548.1 - 0.6 9.2 10.3 0.26 10.4 2.8 2.0 2 0 0 2 2 2 0 Myc amino-terminal region RXT2_N PF08595.6 EDN96548.1 - 1 9.1 5.0 0.52 10.0 0.9 2.3 3 0 0 3 3 3 0 RXT2-like, N-terminal PBP1_TM PF14812.1 EDN96548.1 - 2.6 8.4 5.6 1.6 9.0 1.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prothymosin PF03247.9 EDN96548.1 - 2.7 8.1 18.4 0.034 14.3 5.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.8 EDN96548.1 - 7.4 4.1 12.1 10 3.7 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.9 EDN96548.1 - 8 5.9 8.3 1.5 8.3 3.3 1.6 1 1 1 2 2 2 0 Pox virus Ag35 surface protein GIY-YIG PF01541.19 EDN96549.1 - 3.9e-06 27.1 0.1 4.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 EDN96549.1 - 0.042 14.2 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 T5orf172 domain DUF347 PF03988.7 EDN96550.1 - 0.034 14.0 0.7 0.04 13.8 0.5 1.1 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) LRRC37AB_C PF14914.1 EDN96550.1 - 0.11 11.9 1.2 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF1517 PF07466.6 EDN96550.1 - 0.15 11.0 2.0 0.13 11.1 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3309 PF11752.3 EDN96550.1 - 0.18 11.5 10.5 0.25 11.1 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) EphA2_TM PF14575.1 EDN96550.1 - 0.39 11.1 4.4 0.46 10.9 3.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 EDN96550.1 - 0.6 9.5 4.6 0.67 9.3 3.2 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.1 EDN96550.1 - 4.8 7.3 8.0 5.5 7.1 5.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SP_C-Propep PF08999.5 EDN96550.1 - 6.1 6.3 8.8 7 6.2 6.1 1.1 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PLU-1 PF08429.6 EDN96551.1 - 7.6e-106 353.7 6.9 1e-102 343.5 4.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EDN96551.1 - 2.6e-43 146.8 0.1 6e-43 145.7 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EDN96551.1 - 2.2e-27 94.7 0.1 5.8e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EDN96551.1 - 1.4e-17 63.0 32.8 2e-08 33.7 6.3 3.6 3 0 0 3 3 3 3 PHD-finger zf-C5HC2 PF02928.11 EDN96551.1 - 1.2e-15 57.2 7.0 2.8e-15 56.1 4.8 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 EDN96551.1 - 5.3e-15 54.6 0.8 1.3e-14 53.4 0.6 1.7 1 0 0 1 1 1 1 jmjN domain C1_3 PF07649.7 EDN96551.1 - 0.6 10.1 10.0 0.93 9.5 3.8 2.9 2 0 0 2 2 2 0 C1-like domain C1_1 PF00130.17 EDN96551.1 - 8 6.2 19.0 0.79 9.5 2.3 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CMAS PF02353.15 EDN96552.1 - 2.9e-69 233.1 0.0 4.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EDN96552.1 - 1.3e-07 32.1 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN96552.1 - 0.00038 20.8 0.0 0.00094 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN96552.1 - 0.018 14.1 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDN96552.1 - 0.022 14.1 0.0 0.069 12.5 0.0 1.7 1 1 0 2 2 2 0 Methyltransferase small domain DUF633 PF04816.7 EDN96552.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_31 PF13847.1 EDN96552.1 - 0.057 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GST_N_2 PF13409.1 EDN96553.1 - 2.7e-12 46.5 0.0 5.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN96553.1 - 3.8e-12 46.2 0.0 6.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN96553.1 - 7.6e-10 38.8 0.0 2.3e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN96553.1 - 2.7e-07 30.4 0.1 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN96553.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN96553.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN96554.1 - 1.8e-44 150.9 0.0 3.5e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN96554.1 - 2.3e-06 27.0 0.0 3.6e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN96554.1 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EDN96554.1 - 0.012 16.0 0.0 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F-box PF00646.28 EDN96555.1 - 0.064 12.9 0.4 2.7 7.7 0.4 2.4 2 0 0 2 2 2 0 F-box domain Glyco_hydro_16 PF00722.16 EDN96559.1 - 3.6e-09 36.1 3.7 6.1e-09 35.4 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Synaptonemal_3 PF15191.1 EDN96559.1 - 0.021 14.5 0.1 0.048 13.3 0.0 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 CN_hydrolase PF00795.17 EDN96561.1 - 5.4e-25 87.8 0.1 7.8e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_76 PF03663.9 EDN96562.1 - 2.8e-33 115.8 0.2 3.2e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EDN96562.1 - 4.5e-05 22.8 0.0 0.044 13.0 0.0 2.4 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 EDN96562.1 - 5.8e-05 21.5 0.2 0.38 8.9 0.0 3.3 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 EDN96562.1 - 8.4e-05 21.7 0.7 0.34 9.9 0.2 3.1 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.6 EDN96562.1 - 0.00019 20.6 0.1 0.31 10.0 0.1 2.1 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Aldo_ket_red PF00248.16 EDN96565.1 - 3.5e-27 94.9 0.0 1.5e-24 86.3 0.0 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family AA_permease PF00324.16 EDN96566.1 - 1.4e-72 244.6 35.6 2.1e-65 220.9 19.7 3.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDN96566.1 - 1.6e-22 79.7 30.9 3.8e-22 78.4 21.4 1.5 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_3 PF00933.16 EDN96567.1 - 7.8e-60 202.3 0.0 1.4e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN96567.1 - 1.1e-43 149.4 0.0 1.6e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN96567.1 - 7.4e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_71 PF03659.9 EDN96568.1 - 1.7e-133 444.8 1.0 2.2e-133 444.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EDN96568.1 - 0.072 12.8 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kelch_1 PF01344.20 EDN96569.1 - 0.071 12.6 1.1 0.18 11.3 0.7 1.7 1 0 0 1 1 1 0 Kelch motif Abhydrolase_6 PF12697.2 EDN96570.1 - 1.8e-09 37.8 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN96570.1 - 5.6e-08 32.6 0.0 7.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PLDc_3 PF13918.1 EDN96570.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain Abhydrolase_5 PF12695.2 EDN96570.1 - 0.085 12.6 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos_2 PF14529.1 EDN96572.1 - 1.1e-21 76.5 2.5 1.6e-21 76.1 0.9 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN96572.1 - 1.2e-19 70.5 0.1 2.7e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN96572.1 - 1.5e-14 54.4 0.0 3.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN96572.1 - 6.8e-05 22.9 0.6 0.00012 22.1 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EDN96572.1 - 0.00021 21.5 1.0 0.051 13.8 0.0 3.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.17 EDN96573.1 - 2.4e-61 207.6 0.0 3.7e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EDN96573.1 - 1.2e-51 174.9 0.0 2.5e-51 173.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN96573.1 - 9.7e-08 31.7 0.0 2.9e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN96573.1 - 0.041 13.8 7.3 0.099 12.6 5.1 1.7 1 0 0 1 1 1 0 Zinc knuckle adh_short_C2 PF13561.1 EDN96574.1 - 3.6e-24 85.8 0.0 4.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN96574.1 - 3.2e-21 75.9 0.5 5.2e-21 75.2 0.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN96574.1 - 3e-07 30.2 0.8 1.6e-06 27.8 0.5 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN96574.1 - 0.0032 16.9 0.2 0.29 10.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EDN96574.1 - 0.0033 16.5 0.1 0.0071 15.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EDN96574.1 - 0.0074 16.0 0.9 0.025 14.3 0.5 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EDN96574.1 - 0.02 14.5 0.5 0.03 13.9 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EDN96574.1 - 0.031 13.7 1.0 0.072 12.5 0.7 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3698 PF12479.3 EDN96574.1 - 0.047 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Pyr_redox_3 PF13738.1 EDN96574.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EDN96574.1 - 0.13 12.7 0.9 0.24 11.8 0.6 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NMT1 PF09084.6 EDN96575.1 - 0.0046 16.5 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 NMT1/THI5 like UQ_con PF00179.21 EDN96576.1 - 6.2e-51 171.5 0.0 7e-51 171.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN96576.1 - 0.11 12.2 0.1 0.38 10.5 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Ank_2 PF12796.2 EDN96577.1 - 5.2e-44 148.4 1.6 1.6e-14 54.0 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN96577.1 - 1.7e-27 93.8 0.0 2.2e-05 24.0 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EDN96577.1 - 1.1e-24 84.0 0.1 0.0037 17.3 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EDN96577.1 - 1.1e-24 86.2 0.0 5.7e-08 33.0 0.0 5.6 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN96577.1 - 7.4e-15 54.6 0.0 0.014 15.6 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) KH_1 PF00013.24 EDN96578.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDN96578.1 - 0.009 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 KH domain Glyco_transf_8 PF01501.15 EDN96579.1 - 0.00018 20.9 4.4 0.00052 19.4 3.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDN96579.1 - 0.00043 19.7 0.2 0.00093 18.6 0.1 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Abhydrolase_3 PF07859.8 EDN96583.1 - 3.3e-16 59.5 0.0 4.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN96583.1 - 5e-05 23.0 0.0 9.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDN96583.1 - 0.00011 21.0 0.0 0.0066 15.2 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.2 EDN96583.1 - 0.00061 18.7 0.0 0.00093 18.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EDN96583.1 - 0.0016 17.7 0.1 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EDN96583.1 - 0.011 14.3 0.0 1.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 EDN96583.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase K_channel_TID PF07941.6 EDN96586.1 - 0.021 15.0 0.4 0.023 14.8 0.3 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_18 PF00704.23 EDN96587.1 - 2.8e-12 46.7 0.0 2.1e-11 43.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 DUF2397 PF09660.5 EDN96593.1 - 0.073 11.6 0.1 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) TEBP_beta PF07404.6 EDN96596.1 - 0.8 8.7 2.7 1.6 7.7 1.9 1.5 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Sugar_tr PF00083.19 EDN96597.1 - 2.2e-63 214.4 15.3 5.2e-55 186.8 5.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN96597.1 - 7.5e-22 77.5 23.9 2.9e-20 72.3 8.5 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily DsbD PF02683.10 EDN96597.1 - 0.11 12.0 6.5 0.033 13.7 2.1 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF3357 PF11837.3 EDN96597.1 - 0.26 11.1 0.9 0.76 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF1275 PF06912.6 EDN96597.1 - 1 8.5 15.8 0.013 14.6 3.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) tRNA_int_endo PF01974.12 EDN96598.1 - 3.4e-22 78.0 0.1 7e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EDN96598.1 - 9.1e-05 21.9 0.0 0.024 14.1 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.1 EDN96599.1 - 4.2e-11 42.4 0.0 6.3e-05 22.3 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EDN96599.1 - 1e-09 38.5 0.0 3.5e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDN96599.1 - 2.1e-06 27.5 0.0 0.00026 20.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 2 Toxin_61 PF15538.1 EDN96599.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 61 DUF4450 PF14614.1 EDN96600.1 - 0.13 11.4 0.9 0.18 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) SGS PF05002.10 EDN96601.1 - 1.7e-31 107.8 3.5 1.7e-31 107.8 2.4 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EDN96601.1 - 6.6e-16 58.6 0.1 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EDN96601.1 - 2.8e-09 36.4 1.1 2.8e-09 36.4 0.8 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EDN96601.1 - 3.3e-06 26.5 1.2 0.051 13.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN96601.1 - 0.00012 22.6 4.4 0.00032 21.2 0.4 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN96601.1 - 0.00058 19.3 0.5 0.1 12.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN96601.1 - 0.011 16.2 2.8 1.5 9.7 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN96601.1 - 0.048 13.8 0.4 0.086 12.9 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Prenyltrans_1 PF13243.1 EDN96602.1 - 1.3e-15 57.3 0.2 3.4e-05 23.8 0.1 6.1 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EDN96602.1 - 2.3e-15 56.9 4.6 1.5e-05 25.3 0.1 5.3 3 1 3 6 6 6 5 Prenyltransferase-like Prenyltrans PF00432.16 EDN96602.1 - 1.7e-13 49.8 4.3 6.1e-06 25.6 0.5 3.6 4 0 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EDN96602.1 - 0.00087 18.5 0.1 0.68 9.0 0.0 3.7 5 0 0 5 5 5 2 Pectic acid lyase Chromadorea_ALT PF05535.7 EDN96602.1 - 0.035 14.2 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Chromadorea ALT protein TP6A_N PF04406.9 EDN96603.1 - 1.5e-18 66.2 0.0 3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SPX PF03105.14 EDN96604.1 - 1e-60 205.8 2.1 1e-60 205.8 1.5 2.3 2 0 0 2 2 2 1 SPX domain EXS PF03124.9 EDN96604.1 - 1e-58 199.0 24.3 2.3e-37 128.8 5.5 2.1 1 1 1 2 2 2 2 EXS family Vpu PF00558.14 EDN96604.1 - 0.36 10.4 3.7 1.8 8.1 1.3 2.8 2 1 0 2 2 2 0 Vpu protein Cation_efflux PF01545.16 EDN96607.1 - 6.1e-33 114.1 2.4 8.3e-33 113.6 1.7 1.1 1 0 0 1 1 1 1 Cation efflux family Apis_Csd PF11671.3 EDN96608.1 - 1.5 8.5 4.5 1.6 8.5 3.1 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Wbp11 PF09429.5 EDN96608.1 - 1.5 8.8 12.3 2.4 8.2 8.5 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 Oxysterol_BP PF01237.13 EDN96608.1 - 1.7 7.0 6.4 1.7 7.0 4.5 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein PAF-AH_p_II PF03403.8 EDN96611.1 - 1.1e-49 168.7 0.0 6.5e-49 166.2 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EDN96611.1 - 2.3e-08 33.9 0.0 4.4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EDN96611.1 - 1.5e-06 27.2 0.0 5.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDN96611.1 - 4.3e-06 25.7 0.0 7.7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EDN96611.1 - 0.001 18.9 0.0 0.0061 16.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDN96611.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 EDN96611.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase AAA PF00004.24 EDN96614.1 - 1.4e-16 60.9 0.0 2.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EDN96614.1 - 3.1e-16 59.1 0.0 6.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDN96614.1 - 2.3e-14 53.3 0.0 6.1e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDN96614.1 - 1.9e-10 40.0 0.0 2.6e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDN96614.1 - 3.5e-06 27.1 0.2 4.8e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN96614.1 - 1.1e-05 24.6 0.1 0.00014 20.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDN96614.1 - 1.7e-05 23.6 0.7 0.1 11.2 0.0 3.0 2 1 1 3 3 3 2 TIP49 C-terminus AAA_19 PF13245.1 EDN96614.1 - 2.2e-05 24.1 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDN96614.1 - 2.3e-05 24.4 0.0 0.00087 19.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EDN96614.1 - 4.1e-05 23.2 0.2 0.00016 21.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN96614.1 - 8.4e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EDN96614.1 - 9.4e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 EDN96614.1 - 0.00012 21.7 0.0 0.00034 20.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN96614.1 - 0.00012 21.7 0.1 0.00045 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN96614.1 - 0.0002 20.9 0.0 0.00081 19.0 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EDN96614.1 - 0.00062 19.4 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDN96614.1 - 0.00081 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EDN96614.1 - 0.0062 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EDN96614.1 - 0.0063 15.7 0.3 1.7 7.8 0.0 2.7 2 1 1 3 3 3 1 PhoH-like protein AAA_28 PF13521.1 EDN96614.1 - 0.0095 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EDN96614.1 - 0.01 15.6 0.0 0.14 11.9 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDN96614.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDN96614.1 - 0.013 14.6 0.0 0.11 11.6 0.0 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EDN96614.1 - 0.014 14.8 0.2 2.7 7.3 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain VTC PF09359.5 EDN96614.1 - 0.015 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 VTC domain AAA_17 PF13207.1 EDN96614.1 - 0.032 15.0 0.0 0.061 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDN96614.1 - 0.036 14.3 0.0 0.081 13.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 EDN96614.1 - 0.037 13.4 0.1 0.33 10.3 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EDN96614.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain DEAD PF00270.24 EDN96614.1 - 0.067 12.6 0.1 0.62 9.5 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EDN96614.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EDN96614.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EDN96614.1 - 0.14 10.9 0.0 1.4 7.5 0.0 2.0 1 1 0 2 2 2 0 SNF2 family N-terminal domain DDE_1 PF03184.14 EDN96615.1 - 3.4e-14 52.4 0.0 5.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN96615.1 - 4.9e-09 35.8 0.1 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF904 PF06005.7 EDN96616.1 - 0.001 19.3 1.2 0.0022 18.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) zf-CCHC PF00098.18 EDN96616.1 - 0.0024 17.7 6.0 0.0036 17.1 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Herpes_BLRF2 PF05812.7 EDN96616.1 - 0.017 14.9 4.2 3.8 7.3 0.4 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EDN96616.1 - 0.019 14.9 1.3 0.03 14.2 0.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 EDN96616.1 - 0.04 14.2 0.4 0.057 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 EDN96617.1 - 2.5e-32 111.9 27.5 3.6e-32 111.4 19.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DSX_dimer PF08828.5 EDN96617.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain SHD1 PF03983.7 EDN96618.1 - 1.7e-37 126.8 0.1 3e-37 126.1 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EDN96618.1 - 1.8e-36 123.2 9.0 6.6e-12 44.6 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EDN96618.1 - 3.9e-34 115.9 8.9 3.7e-12 45.6 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EDN96618.1 - 3.3e-26 90.5 1.8 7.6e-08 31.7 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EDN96618.1 - 2.7e-05 24.2 4.8 1.9 8.7 0.0 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain RNA_pol_Rpb5_C PF01191.14 EDN96618.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain GST_N_3 PF13417.1 EDN96619.1 - 1.1e-12 48.0 0.1 2.1e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN96619.1 - 1.4e-08 34.5 0.3 5.4e-07 29.5 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EDN96619.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin WW PF00397.21 EDN96620.1 - 8.1e-06 25.6 0.4 1.7e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 WW domain Tubulin PF00091.20 EDN96622.1 - 3.1e-70 236.3 0.0 4.4e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN96622.1 - 1.1e-48 164.4 0.1 1.9e-48 163.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN96622.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 EDN96623.1 - 2.4e-30 104.3 0.0 1.3e-11 44.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EDN96623.1 - 1.5e-09 37.8 0.0 0.00025 21.1 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN96623.1 - 1.5e-06 27.0 0.0 1.6 8.2 0.0 5.0 5 0 0 5 5 5 1 EF hand UBA PF00627.26 EDN96623.1 - 5.4e-06 26.0 0.1 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain IncA PF04156.9 EDN96623.1 - 0.00011 21.9 18.2 0.00011 21.9 12.6 2.2 1 1 1 2 2 2 1 IncA protein EF-hand_6 PF13405.1 EDN96623.1 - 0.00036 20.1 0.3 6.1 7.0 0.0 4.8 5 0 0 5 5 5 0 EF-hand domain DUF3584 PF12128.3 EDN96623.1 - 0.00046 17.6 24.1 0.00063 17.2 16.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Macoilin PF09726.4 EDN96623.1 - 0.0018 16.6 17.2 0.0029 15.9 12.0 1.3 1 0 0 1 1 1 1 Transmembrane protein EzrA PF06160.7 EDN96623.1 - 0.0045 15.2 17.6 0.0067 14.6 12.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4047 PF13256.1 EDN96623.1 - 0.012 15.5 9.7 0.012 15.5 4.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) EF-hand_8 PF13833.1 EDN96623.1 - 0.031 13.8 0.0 32 4.2 0.0 3.6 3 1 1 4 4 4 0 EF-hand domain pair WEMBL PF05701.6 EDN96623.1 - 0.2 10.0 26.6 0.29 9.5 18.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF1664 PF07889.7 EDN96623.1 - 0.2 11.4 11.7 0.032 14.0 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF960 PF06124.6 EDN96623.1 - 0.22 11.7 0.0 16 5.8 0.0 2.9 3 0 0 3 3 2 0 Staphylococcal protein of unknown function (DUF960) ATG16 PF08614.6 EDN96623.1 - 0.27 11.0 31.2 0.12 12.1 10.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EDN96623.1 - 1.1 9.0 28.3 0.73 9.6 11.3 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EDN96623.1 - 1.2 8.2 16.1 0.27 10.3 3.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EDN96623.1 - 2.3 7.9 26.2 1.2 8.8 3.1 3.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup54 PF13874.1 EDN96623.1 - 2.4 7.8 24.9 0.51 9.9 8.9 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EDN96623.1 - 2.4 7.9 31.1 8.1 6.2 11.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EDN96623.1 - 2.7 7.8 31.1 1 9.2 10.0 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EDN96623.1 - 2.7 6.5 26.9 0.68 8.5 5.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CCDC144C PF14915.1 EDN96623.1 - 2.8 6.7 30.3 1.4 7.8 16.3 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region AAA_13 PF13166.1 EDN96623.1 - 2.8 6.2 22.2 4 5.7 15.4 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EDN96623.1 - 3.4 6.5 29.8 3.4 6.5 8.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EDN96623.1 - 4.7 7.0 31.9 11 5.8 6.1 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding SET PF00856.23 EDN96624.1 - 8.4e-22 78.2 0.2 3.5e-21 76.2 0.1 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EDN96624.1 - 1.1e-18 67.3 8.1 1.1e-18 67.3 5.6 1.9 2 0 0 2 2 2 1 Pre-SET motif Nop52 PF05997.7 EDN96625.1 - 7.5e-53 179.1 0.0 2.3e-42 144.8 0.0 2.0 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EDN96625.1 - 0.018 14.8 0.2 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Gag_p17 PF00540.13 EDN96625.1 - 0.053 13.2 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) EH_Signature PF15611.1 EDN96625.1 - 0.06 12.3 0.4 7 5.5 0.0 2.0 2 0 0 2 2 2 0 EH_Signature domain DAGK_cat PF00781.19 EDN96626.1 - 2.4e-25 88.4 0.0 4.2e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 EDN96627.1 - 1.1e-95 320.9 6.3 2.2e-95 319.9 4.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EDN96627.1 - 4.8e-63 211.0 2.4 1.1e-62 209.8 1.6 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EDN96627.1 - 1.8e-62 208.8 0.0 5.4e-62 207.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EDN96627.1 - 7.1e-09 35.8 5.9 8.6e-05 22.7 0.0 4.4 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EDN96627.1 - 3.2e-05 23.8 8.1 0.011 15.6 0.0 4.1 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDN96627.1 - 0.00056 19.7 0.4 0.67 10.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EDN96627.1 - 0.018 15.5 1.7 1.2 9.7 0.0 4.2 4 1 1 5 5 5 0 HEAT-like repeat RE_Alw26IDE PF09665.5 EDN96627.1 - 0.067 11.8 1.6 1.4 7.5 0.1 2.9 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 EDN96628.1 - 4.3e-54 182.1 0.3 4.8e-54 181.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EDN96629.1 - 5.5e-70 234.4 1.4 7.6e-70 233.9 0.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein HLH PF00010.21 EDN96631.1 - 4.1e-13 48.8 0.1 9.6e-13 47.6 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cellulase PF00150.13 EDN96632.1 - 2e-12 46.8 0.2 3.6e-12 46.0 0.0 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ank PF00023.25 EDN96633.1 - 1.8e-06 27.4 0.1 1.3e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.1 EDN96633.1 - 1.6e-05 25.0 0.0 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 EDN96633.1 - 3.4e-05 23.6 0.0 0.00031 20.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EDN96633.1 - 6.9e-05 23.1 0.0 0.0012 19.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.7 EDN96633.1 - 7.1e-05 22.5 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 EDN96633.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN96633.1 - 0.022 15.2 0.0 0.12 12.9 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNB PF00773.14 EDN96634.1 - 1.1e-94 317.3 0.1 1.9e-94 316.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EDN96634.1 - 1.1e-09 38.5 0.2 5.5e-09 36.2 0.2 2.3 1 1 0 1 1 1 1 PIN domain CRC_subunit PF08624.5 EDN96636.1 - 5.5e-56 188.3 0.1 8e-56 187.8 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HAD_2 PF13419.1 EDN96637.1 - 2.4e-13 50.6 0.0 4.5e-11 43.2 0.0 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN96637.1 - 3.3e-08 33.1 0.0 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN96637.1 - 2.7e-07 31.2 0.0 0.00058 20.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN96637.1 - 0.00022 21.4 0.0 0.00054 20.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EDN96637.1 - 0.054 13.3 0.5 0.32 10.9 0.4 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EDN96638.1 - 6.8e-24 83.5 13.6 1.3e-23 82.6 9.4 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EDN96638.1 - 5.9e-21 74.5 0.1 2.9e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN96638.1 - 4.1e-07 29.9 3.5 0.025 14.4 0.2 3.6 3 1 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 EDN96638.1 - 5e-06 25.8 0.1 8.5e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDN96638.1 - 1.1e-05 24.8 0.0 0.014 14.8 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN96638.1 - 0.00074 18.7 0.2 0.0013 17.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EDN96638.1 - 0.0078 16.7 0.4 3.2 8.2 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EDN96638.1 - 0.01 15.8 2.6 0.065 13.2 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EDN96638.1 - 0.017 13.9 0.1 0.017 13.9 0.1 2.0 3 0 0 3 3 3 0 ArgK protein DUF2277 PF10041.4 EDN96638.1 - 0.034 14.1 0.3 3.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Arf PF00025.16 EDN96638.1 - 0.043 13.0 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_17 PF13207.1 EDN96638.1 - 0.29 11.9 0.1 0.29 11.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Per1 PF04080.8 EDN96640.1 - 4.8e-108 360.6 14.2 5.7e-108 360.3 9.9 1.1 1 0 0 1 1 1 1 Per1-like Homeobox PF00046.24 EDN96641.1 - 1.1e-11 44.1 1.2 1.2e-10 40.8 1.0 2.4 2 0 0 2 2 2 1 Homeobox domain DUF2197 PF09963.4 EDN96644.1 - 0.14 12.1 1.3 0.22 11.4 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Glyco_hydro_35 PF01301.14 EDN96646.1 - 2.1e-77 260.6 0.3 2.8e-77 260.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EDN96646.1 - 1e-65 220.5 0.0 1.7e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EDN96646.1 - 6.1e-52 174.5 12.1 1.2e-29 102.7 2.1 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EDN96646.1 - 3e-22 77.8 0.2 9.8e-22 76.1 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 HTH_Tnp_Tc5 PF03221.11 EDN96647.1 - 1.6e-17 63.0 0.0 2.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN96647.1 - 0.0041 17.0 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.1 EDN96647.1 - 0.006 16.6 0.2 1 9.5 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EDN96647.1 - 0.0063 16.6 0.2 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_psq PF05225.11 EDN96647.1 - 0.024 14.1 0.2 0.053 13.0 0.1 1.7 1 1 0 1 1 1 0 helix-turn-helix, Psq domain MarR_2 PF12802.2 EDN96647.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 MarR family NUMOD1 PF07453.8 EDN96647.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain HTH_6 PF01418.12 EDN96647.1 - 0.061 13.0 0.2 0.49 10.1 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family HTH_23 PF13384.1 EDN96647.1 - 0.065 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.2 EDN96647.1 - 0.072 13.3 0.0 0.32 11.2 0.0 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain DUF3400 PF11880.3 EDN96647.1 - 0.12 11.5 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) HTH_24 PF13412.1 EDN96647.1 - 0.14 11.5 1.1 0.67 9.3 0.0 2.6 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding RNA_pol_3_Rpc31 PF11705.3 EDN96649.1 - 0.088 12.7 7.6 0.091 12.6 5.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1087 PF06465.8 EDN96649.1 - 0.6 10.0 2.9 0.56 10.1 1.2 1.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1087) Tyrosinase PF00264.15 EDN96650.1 - 1.2e-56 192.3 4.3 1.4e-56 192.2 2.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Methyltransf_31 PF13847.1 EDN96654.1 - 2.1e-11 43.6 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN96654.1 - 7.6e-11 41.6 0.0 1.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EDN96654.1 - 1.4e-09 37.3 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EDN96654.1 - 2.5e-08 34.4 0.0 7.1e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN96654.1 - 1.1e-07 31.8 0.0 5.2e-07 29.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN96654.1 - 4.7e-07 30.2 0.0 1.2e-06 28.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDN96654.1 - 4.4e-05 22.3 0.1 7.1e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EDN96654.1 - 6.7e-05 23.1 0.0 0.0004 20.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN96654.1 - 0.00013 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN96654.1 - 0.00044 20.6 0.0 0.00094 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDN96654.1 - 0.00092 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EDN96654.1 - 0.00094 18.5 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EDN96654.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EDN96654.1 - 0.098 13.4 0.0 0.21 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TFIIB PF00382.14 EDN96655.1 - 2.4e-24 84.9 0.1 1.1e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EDN96655.1 - 5e-22 77.9 7.8 2e-21 76.0 1.7 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EDN96655.1 - 0.0044 16.2 1.4 0.012 14.9 1.0 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EDN96655.1 - 0.03 13.9 0.1 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain PGM_PMM_I PF02878.11 EDN96656.1 - 1.5e-17 63.3 0.0 2.7e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDN96656.1 - 8.9e-17 61.3 0.3 4.8e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDN96656.1 - 2.3e-13 49.9 1.0 7.7e-13 48.2 0.3 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EDN96656.1 - 0.00048 20.1 0.1 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF2358 PF10184.4 EDN96657.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 EDN96657.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain ERCC4 PF02732.10 EDN96658.1 - 6.7e-26 90.7 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain MutL PF13941.1 EDN96658.1 - 0.078 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 MutL protein Carn_acyltransf PF00755.15 EDN96663.1 - 2.8e-154 514.4 0.0 3.5e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3829 PF12889.2 EDN96663.1 - 0.22 10.7 1.1 0.34 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) NmrA PF05368.8 EDN96665.1 - 5e-37 127.3 0.0 6.1e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN96665.1 - 1.3e-12 48.0 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN96665.1 - 0.00069 19.1 0.0 0.0041 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN96665.1 - 0.0016 17.2 0.0 0.0032 16.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EDN96665.1 - 0.0098 15.8 0.0 0.03 14.2 0.0 1.8 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EDN96665.1 - 0.014 14.2 0.0 0.22 10.3 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN96665.1 - 0.033 13.1 0.0 1.7 7.4 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein KR PF08659.5 EDN96665.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 KR domain VHS PF00790.14 EDN96666.1 - 2.2e-05 24.1 0.0 5.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.8 EDN96666.1 - 0.00065 19.8 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EDN96666.1 - 0.00093 19.2 0.2 0.0029 17.7 0.1 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 DUF2387 PF09526.5 EDN96666.1 - 0.047 13.6 0.9 0.7 9.8 0.1 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 EDN96666.1 - 0.76 10.2 3.7 10 6.6 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDN96666.1 - 1.2 8.9 4.9 5.2 6.8 0.2 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 EDN96667.1 - 0.0057 17.1 0.0 0.0083 16.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 ATP-synt_8 PF00895.15 EDN96667.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 CH PF00307.26 EDN96668.1 - 0.023 14.7 0.3 0.14 12.2 0.0 2.5 2 0 0 2 2 2 0 Calponin homology (CH) domain WXG100 PF06013.7 EDN96668.1 - 4.7 7.2 14.2 3.4 7.7 0.4 4.8 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Mak10 PF04112.8 EDN96669.1 - 7.3e-19 67.6 0.5 2.6e-16 59.2 0.0 2.6 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EDN96670.1 - 6.5e-23 80.0 1.7 1.2e-22 79.2 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 EDN96671.1 - 1.3e-15 57.4 0.1 2.3e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDN96671.1 - 1.9e-11 44.0 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EDN96672.1 - 1.8e-89 299.6 0.3 4.1e-87 291.9 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EDN96672.1 - 4.3e-15 55.3 6.0 2.4e-11 43.3 0.7 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EDN96672.1 - 0.2 11.1 2.4 6.2 6.3 0.1 3.0 2 1 1 3 3 3 0 TFIIE alpha subunit Ribosomal_L11 PF00298.14 EDN96672.1 - 0.27 11.3 1.6 0.36 11.0 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Mito_carr PF00153.22 EDN96673.1 - 1.3e-28 98.4 0.9 4.4e-15 55.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 EDN96674.1 - 4.2e-08 32.6 0.0 6.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Atg8 PF02991.11 EDN96676.1 - 2.8e-51 171.8 0.2 3.3e-51 171.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EDN96676.1 - 2.7e-06 27.4 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 EDN96677.1 - 5.9e-137 455.0 0.1 7e-137 454.8 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Herpes_glycop PF01528.11 EDN96677.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M SWIM PF04434.12 EDN96678.1 - 0.00032 20.1 0.0 0.097 12.1 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger BLIP PF07467.6 EDN96678.1 - 0.19 11.3 2.4 0.3 10.7 1.7 1.2 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) MitMem_reg PF13012.1 EDN96679.1 - 1.1e-39 135.1 0.5 2e-39 134.2 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EDN96679.1 - 3.3e-27 94.5 0.0 9.9e-27 92.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4407 PF14362.1 EDN96679.1 - 0.52 9.2 4.4 0.81 8.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADK PF00406.17 EDN96680.1 - 2.2e-58 196.3 0.0 2.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDN96680.1 - 2.4e-13 49.5 0.0 6.6e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EDN96680.1 - 4.1e-06 26.7 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN96680.1 - 3e-05 24.8 0.0 5e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN96680.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN96680.1 - 0.014 14.4 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin BLOC1_2 PF10046.4 EDN96680.1 - 0.086 12.9 0.2 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynamin_M PF01031.15 EDN96682.1 - 1.1e-114 382.1 0.0 3.7e-114 380.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EDN96682.1 - 1.2e-55 187.8 0.0 1.2e-55 187.8 0.0 2.1 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EDN96682.1 - 2.3e-31 107.5 2.2 2.3e-31 107.5 1.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDN96682.1 - 0.00086 19.2 0.2 0.0064 16.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN96682.1 - 0.011 16.2 0.0 0.039 14.4 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein WD40 PF00400.27 EDN96684.1 - 1.8e-25 87.8 2.0 2.9e-09 36.4 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 EDN96684.1 - 2.5e-10 40.1 3.9 1.1e-09 38.1 2.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EDN96684.1 - 8.3e-06 25.6 0.1 0.00034 20.3 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EDN96684.1 - 2.7e-05 23.1 0.0 0.00013 20.9 0.0 2.0 2 1 1 3 3 3 1 Coatomer WD associated region IKI3 PF04762.7 EDN96684.1 - 0.029 12.2 0.0 0.055 11.2 0.0 1.5 1 0 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.3 EDN96684.1 - 0.17 11.7 1.2 0.44 10.4 0.8 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.27 EDN96685.1 - 6.5e-23 79.7 11.4 0.0013 18.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EDN96685.1 - 2.3 8.5 6.8 2.8 8.3 0.0 4.1 5 1 1 6 6 6 0 PQQ-like domain Bac_rhodopsin PF01036.13 EDN96688.1 - 8.4e-49 165.8 20.5 9.9e-49 165.6 14.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Intg_mem_TP0381 PF09529.5 EDN96688.1 - 0.00044 19.5 8.3 0.0029 16.8 1.5 2.4 2 0 0 2 2 2 2 Integral membrane protein (intg_mem_TP0381) DUF4305 PF14146.1 EDN96688.1 - 0.012 15.2 1.4 0.012 15.2 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) Wzy_C PF04932.10 EDN96688.1 - 0.033 13.9 0.7 0.033 13.9 0.5 2.3 1 1 1 2 2 2 0 O-Antigen ligase DUF4131 PF13567.1 EDN96688.1 - 0.14 11.6 9.3 0.38 10.1 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HTH_psq PF05225.11 EDN96689.1 - 2e-09 36.8 2.1 6.5e-08 32.0 0.2 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain DivIC PF04977.10 EDN96689.1 - 0.054 12.9 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator ACT_7 PF13840.1 EDN96690.1 - 1.5e-18 66.0 0.0 1.1e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 ACT domain DGCR6 PF07324.6 EDN96690.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein CTD_bind PF04818.8 EDN96691.1 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAT1 PF09770.4 EDN96691.1 - 0.046 11.9 20.1 0.063 11.5 14.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exo_endo_phos PF03372.18 EDN96695.1 - 4e-25 89.2 3.1 4e-25 89.1 0.5 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EDN96695.1 - 0.13 12.0 0.2 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region GFA PF04828.9 EDN96696.1 - 6.7e-11 41.9 2.8 6.7e-11 41.9 2.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Mito_carr PF00153.22 EDN96698.1 - 1.3e-27 95.3 8.4 1.4e-11 43.9 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EDN96699.1 - 2.8e-93 312.4 0.0 1.7e-92 309.8 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EDN96699.1 - 0.043 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone RRM_5 PF13893.1 EDN96700.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN96700.1 - 1.6e-07 30.8 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN96700.1 - 6e-07 29.3 0.1 1.3e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EDN96700.1 - 0.0006 19.9 0.0 0.0019 18.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Cu-oxidase_2 PF07731.9 EDN96701.1 - 5.2e-45 152.3 7.2 1.3e-40 138.1 0.4 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDN96701.1 - 1.7e-40 137.3 2.6 2.1e-38 130.6 0.5 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EDN96701.1 - 3.4e-38 131.0 2.8 4e-33 114.5 0.2 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EDN96701.1 - 0.0049 16.7 0.0 24 4.8 0.0 4.1 4 0 0 4 4 4 1 Cupredoxin-like domain FTR1 PF03239.9 EDN96702.1 - 4.5e-66 222.8 10.3 4.5e-66 222.8 7.1 2.1 1 1 1 2 2 2 2 Iron permease FTR1 family DUF3169 PF11368.3 EDN96702.1 - 0.01 15.0 2.3 0.044 12.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) XK-related PF09815.4 EDN96702.1 - 0.021 13.8 0.2 0.021 13.8 0.1 2.3 1 1 0 2 2 2 0 XK-related protein Dor1 PF04124.7 EDN96703.1 - 4.6e-53 179.8 3.5 8.4e-43 146.1 4.7 2.1 2 0 0 2 2 2 2 Dor1-like family PBP1_TM PF14812.1 EDN96703.1 - 0.33 11.2 3.7 0.79 10.0 2.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.11 EDN96705.1 - 3.8e-53 180.0 9.5 5.4e-53 179.4 6.6 1.2 1 0 0 1 1 1 1 TLC domain Cytochrom_B561 PF03188.11 EDN96705.1 - 0.019 14.8 1.0 0.045 13.5 0.6 1.7 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 PLAC8 PF04749.12 EDN96706.1 - 4.1e-18 65.8 18.8 4.8e-18 65.6 13.0 1.0 1 0 0 1 1 1 1 PLAC8 family PP2C PF00481.16 EDN96707.1 - 2.5e-35 122.0 0.0 2.4e-28 99.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDN96707.1 - 0.0015 18.0 0.0 0.0034 16.7 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Fructosamin_kin PF03881.9 EDN96708.1 - 5.6e-64 215.8 0.0 6.4e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 EDN96708.1 - 0.01 14.5 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EDN96708.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.15 EDN96708.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Mif2_N PF15624.1 EDN96709.1 - 4.9e-35 121.0 1.3 4.9e-35 121.0 0.9 4.0 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EDN96709.1 - 1.5e-27 95.4 0.2 2.5e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EDN96709.1 - 0.0037 16.7 0.0 0.0078 15.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain RNase_HII PF01351.13 EDN96710.1 - 8.3e-46 156.1 0.0 6e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease HII Nic96 PF04097.9 EDN96711.1 - 2.6e-199 663.3 0.0 3.2e-199 663.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EDN96711.1 - 4.4e-13 49.4 91.2 1.3e-08 35.0 23.2 3.3 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF3425 PF11905.3 EDN96712.1 - 6.6e-34 116.7 0.1 1.3e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDN96712.1 - 0.02 14.8 8.2 0.041 13.8 5.5 1.7 1 1 0 1 1 1 0 bZIP transcription factor Metal_resist PF13801.1 EDN96712.1 - 0.98 9.4 7.3 0.22 11.5 2.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance FGGY_C PF02782.11 EDN96714.1 - 1.5e-50 171.6 0.6 2.1e-50 171.0 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDN96714.1 - 9.5e-22 77.4 0.1 5.6e-19 68.4 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AAA PF00004.24 EDN96715.1 - 1.7e-43 147.9 0.0 2.7e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN96715.1 - 8.8e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN96715.1 - 3.6e-07 30.2 0.0 5.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN96715.1 - 3e-06 27.3 0.0 6.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN96715.1 - 4.6e-06 26.8 0.0 0.00024 21.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN96715.1 - 0.00011 21.9 0.0 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN96715.1 - 0.00011 22.9 0.0 0.00024 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN96715.1 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDN96715.1 - 0.0004 19.8 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EDN96715.1 - 0.0012 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDN96715.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN96715.1 - 0.0028 16.7 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EDN96715.1 - 0.0036 17.2 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN96715.1 - 0.0038 17.1 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDN96715.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EDN96715.1 - 0.0072 15.5 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDN96715.1 - 0.0082 16.4 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain KaiC PF06745.8 EDN96715.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EDN96715.1 - 0.017 14.5 0.1 0.093 12.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN96715.1 - 0.02 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EDN96715.1 - 0.026 14.0 0.0 0.098 12.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 EDN96715.1 - 0.027 13.4 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EDN96715.1 - 0.028 13.6 0.0 0.076 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EDN96715.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EDN96715.1 - 0.052 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EDN96715.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EDN96715.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EDN96715.1 - 0.085 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EDN96715.1 - 0.11 12.1 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF307 PF03733.8 EDN96716.1 - 4.2e-17 62.3 13.4 6.8e-17 61.6 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF307) COPR5 PF15340.1 EDN96716.1 - 0.037 14.4 1.9 0.093 13.0 0.8 2.1 2 0 0 2 2 2 0 Cooperator of PRMT5 family Na_Ca_ex PF01699.19 EDN96717.1 - 4.2e-33 113.8 34.7 1.4e-18 66.8 8.1 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PV-1 PF06637.6 EDN96717.1 - 0.14 10.7 0.1 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) F-box PF00646.28 EDN96719.1 - 0.0014 18.2 0.4 0.0039 16.8 0.3 1.9 1 0 0 1 1 1 1 F-box domain HSF_DNA-bind PF00447.12 EDN96720.1 - 8.4e-13 48.3 0.4 3.1e-09 36.9 0.1 2.3 1 1 1 2 2 2 2 HSF-type DNA-binding ABM PF03992.11 EDN96722.1 - 0.0038 17.2 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MHCassoc_trimer PF08831.5 EDN96722.1 - 0.11 12.3 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF3733 PF12534.3 EDN96722.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 WD40 PF00400.27 EDN96723.1 - 1.2e-07 31.3 11.6 0.021 14.7 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat SAP PF02037.22 EDN96724.1 - 3e-05 23.4 0.0 5.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain MFS_1 PF07690.11 EDN96725.1 - 1.2e-40 139.3 49.7 1.2e-40 139.3 34.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN96725.1 - 5e-15 55.0 13.2 5e-15 55.0 9.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EDN96725.1 - 0.0091 15.7 6.3 0.011 15.5 0.3 3.3 3 1 0 3 3 3 1 MFS_1 like family CN_hydrolase PF00795.17 EDN96726.1 - 4.9e-30 104.2 0.0 8.2e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4236 PF14020.1 EDN96726.1 - 0.07 13.2 0.8 0.15 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Dehydratase_hem PF13816.1 EDN96727.1 - 2.7e-55 187.6 0.0 4.3e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase DUF1919 PF08942.5 EDN96728.1 - 0.015 14.6 0.0 0.016 14.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) MFS_1 PF07690.11 EDN96730.1 - 3.2e-36 124.7 38.3 3.2e-36 124.7 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN96730.1 - 9e-09 34.4 37.8 0.00015 20.4 10.7 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Ni_hydr_CYTB PF01292.15 EDN96730.1 - 0.72 9.2 11.7 0.034 13.5 3.8 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Rick_17kDa_Anti PF05433.10 EDN96730.1 - 7.8 6.2 11.3 0.5 10.0 3.8 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain An_peroxidase PF03098.10 EDN96731.1 - 7.8e-85 285.2 0.0 1.5e-82 277.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EDN96731.1 - 1.9e-07 30.0 0.0 3.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_3 PF01757.17 EDN96732.1 - 1.4e-24 86.5 19.9 2.3e-24 85.8 13.8 1.3 1 0 0 1 1 1 1 Acyltransferase family Sdh_cyt PF01127.17 EDN96735.1 - 7.1e-22 77.5 3.8 9.3e-22 77.1 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_hydro_1 PF00232.13 EDN96736.1 - 7.8e-100 334.1 0.3 9.7e-100 333.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TGT PF01702.13 EDN96737.1 - 3.7e-36 124.6 0.0 4.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.14 EDN96738.1 - 3.6e-21 74.9 0.4 6e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 LCCL domain CAF1A PF12253.3 EDN96741.1 - 1.3e-24 86.0 5.8 1.3e-24 86.0 4.0 3.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A MIP-T3 PF10243.4 EDN96741.1 - 3.8e-05 22.3 39.8 3.8e-05 22.3 27.6 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 EDN96741.1 - 0.0064 14.8 25.0 0.0095 14.2 17.3 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein Ycf1 PF05758.7 EDN96741.1 - 0.0064 14.2 16.2 0.01 13.5 11.3 1.5 1 0 0 1 1 1 1 Ycf1 Neur_chan_memb PF02932.11 EDN96741.1 - 1 9.1 9.7 2.9 7.7 6.7 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med3 PF11593.3 EDN96742.1 - 3.3 6.8 10.9 3.5 6.7 7.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nop25 PF09805.4 EDN96745.1 - 0.024 14.7 0.7 0.03 14.3 0.5 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1577 PF07614.6 EDN96747.1 - 0.099 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Neurochondrin PF05536.6 EDN96749.1 - 0.081 11.2 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin Ank_2 PF12796.2 EDN96750.1 - 3.7e-29 100.8 0.7 3e-16 59.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN96750.1 - 6.8e-18 63.5 0.7 2.4e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDN96750.1 - 2.9e-17 62.6 0.1 3.1e-10 40.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN96750.1 - 1.3e-14 53.8 0.1 1.4e-10 41.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN96750.1 - 1.6e-14 52.5 1.0 6.4e-09 35.1 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat MscL PF01741.13 EDN96751.1 - 1.3e-12 47.9 0.1 6.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 EDN96751.1 - 0.037 13.7 3.0 0.037 13.7 2.1 2.6 2 1 1 3 3 3 0 BED zinc finger Glyco_hydro_31 PF01055.21 EDN96752.1 - 1.1e-154 515.5 4.8 1.4e-154 515.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN96752.1 - 4e-23 81.0 0.1 1.2e-22 79.5 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EDN96753.1 - 2e-53 179.7 0.0 2.3e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UME PF08064.8 EDN96755.1 - 0.038 13.9 0.8 0.066 13.1 0.5 1.5 1 0 0 1 1 1 0 UME (NUC010) domain GCD14 PF08704.5 EDN96756.1 - 1.1e-61 208.5 0.0 4.6e-42 144.2 0.0 2.5 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Acyl_CoA_thio PF02551.10 EDN96756.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase tRNA-synt_1e PF01406.14 EDN96757.1 - 1.7e-86 290.0 0.0 9.3e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.6 EDN96757.1 - 0.046 13.9 0.0 0.046 13.9 0.0 2.0 2 0 0 2 2 2 0 DALR domain tRNA-synt_1g PF09334.6 EDN96757.1 - 0.046 12.3 0.0 0.11 11.1 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 EDN96757.1 - 0.14 10.7 2.2 0.19 10.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain zf-C2H2 PF00096.21 EDN96758.1 - 2.8e-12 46.1 7.2 1.9e-05 24.6 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN96758.1 - 6.9e-12 44.8 7.8 4.8e-06 26.5 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN96758.1 - 8.1e-09 35.3 9.3 2.6e-05 24.2 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDN96758.1 - 1.1e-05 25.0 4.1 0.013 15.3 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EDN96758.1 - 0.0031 17.6 2.0 0.013 15.6 1.5 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Fungal_trans PF04082.13 EDN96758.1 - 0.0071 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRN7 PF11781.3 EDN96758.1 - 0.018 14.5 0.7 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 EDN96758.1 - 0.033 14.3 1.9 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EDN96758.1 - 0.17 11.6 0.6 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 BED zinc finger DUF2225 PF09986.4 EDN96758.1 - 0.18 11.2 0.4 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.1 EDN96758.1 - 9 6.7 5.9 3.4 8.0 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain adh_short PF00106.20 EDN96759.1 - 1.3e-23 83.7 3.5 5.5e-23 81.7 2.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN96759.1 - 6.8e-18 65.3 0.5 3.4e-16 59.7 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN96759.1 - 5.8e-09 35.8 0.3 1.5e-08 34.5 0.3 1.6 2 0 0 2 2 2 1 KR domain HHH_5 PF14520.1 EDN96759.1 - 0.001 19.1 0.2 0.095 12.8 0.2 2.8 1 1 0 1 1 1 1 Helix-hairpin-helix domain Hema_stalk PF08720.5 EDN96759.1 - 0.11 11.9 0.8 0.17 11.3 0.6 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Carb_kinase PF01256.12 EDN96760.1 - 5.1e-56 189.6 0.0 6e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EDN96760.1 - 0.00022 20.4 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EDN96760.1 - 0.036 13.2 0.0 0.35 10.0 0.0 2.1 1 1 0 2 2 2 0 Phosphomethylpyrimidine kinase Sigma70_r2 PF04542.9 EDN96760.1 - 0.12 11.9 0.0 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 2 Shal-type PF11601.3 EDN96762.1 - 0.47 10.0 2.0 0.37 10.3 0.3 1.7 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels CENP-Q PF13094.1 EDN96763.1 - 1.9 8.4 42.3 0.14 12.2 12.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lipase PF00151.14 EDN96763.1 - 2.4 7.2 7.5 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Lipase DUF3453 PF11935.3 EDN96765.1 - 5.3e-31 107.8 3.3 1.8e-26 93.0 0.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3453) XPA_C PF05181.7 EDN96765.1 - 0.068 12.7 0.1 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 XPA protein C-terminus DUF3666 PF12408.3 EDN96765.1 - 0.075 12.1 0.3 0.22 10.6 0.2 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Coiled-coil_56 PF09813.4 EDN96766.1 - 0.00068 19.5 0.0 0.00076 19.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.6 EDN96767.1 - 6e-29 101.0 5.1 6e-29 101.0 3.6 3.1 2 2 0 2 2 2 1 Sds3-like DTHCT PF08070.6 EDN96767.1 - 5.9 7.6 11.5 9.8 6.9 3.2 3.5 2 1 1 3 3 3 0 DTHCT (NUC029) region RRM_5 PF13893.1 EDN96768.1 - 0.0037 17.0 0.1 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EDN96770.1 - 5.1e-22 78.0 27.4 2.4e-11 42.8 6.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN96770.1 - 5.3e-12 45.1 51.9 4.2e-08 32.3 7.4 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF973 PF06157.6 EDN96770.1 - 0.0072 15.3 3.1 0.011 14.6 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) MRI PF15325.1 EDN96771.1 - 0.2 12.6 1.5 0.26 12.2 1.0 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Ribosomal_S19 PF00203.16 EDN96772.1 - 2e-33 113.8 0.3 2.9e-33 113.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3386 PF11866.3 EDN96772.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Ribosomal_60s PF00428.14 EDN96773.1 - 1.7e-29 102.0 9.5 2e-29 101.8 6.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.6 EDN96774.1 - 0.15 12.3 25.8 6.8 7.0 17.9 2.5 1 1 0 1 1 1 0 SPT2 chromatin protein Fungal_trans_2 PF11951.3 EDN96775.1 - 7.2e-07 28.1 0.1 1.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 EDN96776.1 - 3.1e-139 463.5 0.5 3.5e-139 463.3 0.4 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDN96776.1 - 2.7e-09 36.4 0.1 4.2e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDN96776.1 - 1.7e-07 30.6 0.6 2.9e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EDN96776.1 - 2.8e-07 29.6 1.9 3.4e-07 29.3 0.7 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDN96776.1 - 0.0013 17.9 0.8 0.003 16.7 0.6 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_3 PF07859.8 EDN96777.1 - 6.6e-48 163.0 0.0 8.1e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN96777.1 - 7.9e-11 41.3 0.0 1.8e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EDN96777.1 - 3.2e-05 23.7 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN96777.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 EDN96777.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein NUFIP1 PF10453.4 EDN96778.1 - 5.7e-12 44.9 0.2 5.7e-12 44.9 0.1 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EDN96778.1 - 0.093 12.4 5.1 0.17 11.6 3.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC45 PF02724.9 EDN96778.1 - 1.2 7.0 8.4 2.1 6.2 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rbc25 PF08292.7 EDN96779.1 - 1.2e-38 132.0 0.5 2e-38 131.3 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDN96779.1 - 0.0015 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Orbi_VP7 PF00897.12 EDN96780.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 Creb_binding PF09030.5 EDN96781.1 - 0.081 13.1 2.2 0.18 12.0 1.5 1.5 1 0 0 1 1 1 0 Creb binding LSM PF01423.17 EDN96782.1 - 5.1e-15 54.7 1.0 6.4e-15 54.4 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN96782.1 - 0.0032 17.3 0.1 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DRMBL PF07522.9 EDN96783.1 - 1.3e-34 118.5 0.0 3.4e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EDN96783.1 - 4.2e-13 49.2 0.0 9e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1752 PF08550.5 EDN96785.1 - 3.3e-11 42.5 2.0 6.7e-11 41.5 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1325 PF07039.6 EDN96785.1 - 0.00071 19.1 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Met_10 PF02475.11 EDN96788.1 - 6.4e-61 205.4 0.3 8e-61 205.1 0.2 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 EDN96788.1 - 0.0092 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_26 PF13659.1 EDN96788.1 - 0.055 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 EDN96789.1 - 4.4e-28 98.4 0.0 5.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec10 PF07393.6 EDN96791.1 - 2.4e-224 746.7 2.3 3.2e-224 746.2 1.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF4226 PF10774.4 EDN96791.1 - 0.036 14.0 0.5 2.9 7.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) Baculo_PEP_C PF04513.7 EDN96791.1 - 1.6 8.5 8.9 0.25 11.1 0.6 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COX17 PF05051.8 EDN96792.1 - 3.4e-20 71.7 5.6 4.2e-20 71.5 3.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) LRR_6 PF13516.1 EDN96793.1 - 5.7e-09 35.1 13.5 0.021 14.8 0.0 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EDN96793.1 - 4.2e-05 23.0 14.9 0.022 14.3 0.3 5.6 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDN96793.1 - 0.0019 17.9 3.8 36 4.9 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 EDN96793.1 - 0.018 14.7 9.0 0.25 11.1 0.1 3.8 4 2 0 4 4 4 0 Leucine rich repeat Radial_spoke PF04712.7 EDN96793.1 - 0.47 9.1 0.0 0.47 9.1 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein SLAC1 PF03595.12 EDN96794.1 - 6.3e-58 195.9 30.2 7.1e-58 195.8 20.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phe_ZIP PF08916.6 EDN96797.1 - 0.051 13.8 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Phenylalanine zipper CBFB_NFYA PF02045.10 EDN96799.1 - 8e-30 103.1 4.3 1.7e-29 102.1 3.0 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.8 EDN96799.1 - 1.9 8.3 25.4 7.3 6.3 17.6 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAS PF03059.11 EDN96800.1 - 4.3e-95 318.0 0.0 6e-95 317.5 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EDN96800.1 - 0.0018 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain EST1_DNA_bind PF10373.4 EDN96800.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain FAT PF02259.18 EDN96801.1 - 4.8e-78 262.6 3.1 1e-77 261.4 2.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EDN96801.1 - 1.2e-30 106.7 0.2 4.2e-30 104.9 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EDN96801.1 - 5.3e-10 38.5 0.2 1.3e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_12 PF13424.1 EDN96801.1 - 0.024 14.5 1.3 0.3 11.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S58 PF03576.9 EDN96802.1 - 0.093 11.8 1.2 0.16 11.1 0.8 1.3 1 0 0 1 1 1 0 Peptidase family S58 YbaB_DNA_bd PF02575.11 EDN96802.1 - 1.7 8.6 6.8 4 7.3 0.7 2.8 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family ParA PF10609.4 EDN96803.1 - 1.1e-35 121.2 0.1 2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDN96803.1 - 2.8e-13 49.6 0.0 4.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EDN96803.1 - 3.5e-06 26.3 0.0 6.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EDN96803.1 - 0.00011 21.4 1.1 0.00019 20.6 0.4 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EDN96803.1 - 0.00011 22.1 0.1 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN96803.1 - 0.0056 16.1 0.2 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EDN96803.1 - 0.0092 14.7 0.6 0.016 14.0 0.4 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 EDN96803.1 - 0.022 14.1 0.4 0.037 13.4 0.3 1.5 1 1 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 EDN96803.1 - 0.024 13.8 0.5 0.098 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Aminotran_1_2 PF00155.16 EDN96804.1 - 9.3e-11 41.2 0.0 1e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Tannase PF07519.6 EDN96804.1 - 0.01 14.6 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 EDN96805.1 - 7e-55 185.8 0.0 8.8e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN96805.1 - 0.0013 18.0 0.0 0.004 16.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDN96805.1 - 0.0047 16.8 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN96805.1 - 0.034 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EDN96805.1 - 0.14 11.3 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.27 EDN96806.1 - 1.5e-25 88.0 9.6 8.6e-08 31.7 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ricin_B_lectin PF00652.17 EDN96806.1 - 0.072 13.1 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Fungal_trans PF04082.13 EDN96807.1 - 5.4e-26 91.0 0.2 9.3e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN96807.1 - 9.2e-07 28.6 8.6 2.1e-06 27.5 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP PF00230.15 EDN96810.1 - 1.2e-47 162.3 15.2 1.6e-47 161.8 10.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Ureide_permease PF07168.6 EDN96810.1 - 0.006 15.3 0.7 0.0095 14.6 0.5 1.4 1 0 0 1 1 1 1 Ureide permease 2TM PF13239.1 EDN96810.1 - 4.9 7.2 5.0 3.2 7.8 0.1 2.6 3 0 0 3 3 3 0 2TM domain Beta-lactamase PF00144.19 EDN96811.1 - 8.1e-43 146.6 0.0 1.3e-42 146.0 0.0 1.2 1 1 0 1 1 1 1 Beta-lactamase Glyco_transf_15 PF01793.11 EDN96815.1 - 4.5e-137 456.4 12.1 5.5e-137 456.1 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EDN96816.1 - 1.5e-57 195.1 9.3 1.5e-57 195.1 6.5 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family RSS_P20 PF11757.3 EDN96816.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.8 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like SAM_decarbox PF01536.11 EDN96819.1 - 2.3e-87 292.7 0.0 1.1e-61 208.3 0.0 3.0 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase Ribonucleas_3_3 PF14622.1 EDN96820.1 - 7.3e-25 87.3 0.0 1.5e-24 86.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDN96820.1 - 7.7e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 EDN96821.1 - 4.1e-05 22.8 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein RTA1 PF04479.8 EDN96822.1 - 8.5e-19 67.9 9.6 1.5e-18 67.1 6.7 1.3 1 0 0 1 1 1 1 RTA1 like protein Glycos_transf_1 PF00534.15 EDN96824.1 - 0.014 14.7 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 BRCT PF00533.21 EDN96825.1 - 2.7e-07 30.6 0.0 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Mannitol_dh_C PF08125.8 EDN96827.1 - 0.015 14.4 0.1 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain KfrA_N PF11740.3 EDN96827.1 - 0.047 14.1 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RRM_5 PF13893.1 EDN96828.1 - 9.8e-07 28.5 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN96828.1 - 1.4e-06 27.8 0.1 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN96828.1 - 1.8e-05 24.6 0.1 5.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SnoaL_4 PF13577.1 EDN96829.1 - 2.4e-09 37.1 0.0 2.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain ThiW PF09512.5 EDN96829.1 - 0.017 14.9 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) SnoaL_2 PF12680.2 EDN96829.1 - 0.029 14.7 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.7 EDN96829.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase p450 PF00067.17 EDN96831.1 - 1.1e-72 245.0 0.0 1.3e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 EDN96832.1 - 8.5e-37 126.5 0.0 1.4e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN96832.1 - 6.7e-13 48.2 0.1 1.6e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN96832.1 - 6.8e-10 39.3 0.0 1.6e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN96832.1 - 8.7e-06 25.8 0.1 2.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 EDN96833.1 - 1.8e-58 198.2 14.0 4.3e-42 144.2 3.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN96833.1 - 8.5e-10 37.8 19.0 5e-08 32.0 6.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Rad17 PF03215.10 EDN96834.1 - 3e-61 207.6 0.0 5.3e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDN96834.1 - 0.002 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN96834.1 - 0.0028 17.8 0.0 0.0089 16.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDN96834.1 - 0.0054 16.4 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EDN96834.1 - 0.0091 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EDN96834.1 - 0.013 16.3 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN96834.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EDN96834.1 - 0.03 13.8 0.2 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN96834.1 - 0.036 14.3 0.0 0.085 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDN96834.1 - 0.043 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Herpes_Helicase PF02689.9 EDN96834.1 - 0.077 10.7 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 Helicase UPF0079 PF02367.12 EDN96834.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EDN96834.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDN96834.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EDN96834.1 - 0.17 11.5 0.6 0.41 10.2 0.2 1.8 2 0 0 2 2 2 0 NACHT domain PUF PF00806.14 EDN96835.1 - 7.4e-37 122.7 2.0 8.3e-06 24.9 0.0 9.1 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EDN96835.1 - 0.072 13.7 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of ribonuclease activity B MRP-S33 PF08293.6 EDN96836.1 - 2.4e-34 117.1 0.4 3.2e-34 116.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PBP1_TM PF14812.1 EDN96836.1 - 0.039 14.2 0.6 0.061 13.6 0.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SURF2 PF05477.6 EDN96836.1 - 0.052 12.6 1.7 0.07 12.2 1.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ACBP PF00887.14 EDN96838.1 - 5.1e-31 106.1 0.0 8.2e-31 105.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein GFA PF04828.9 EDN96839.1 - 7.1e-22 77.1 0.1 9.5e-22 76.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 EDN96839.1 - 0.12 12.6 0.8 10 6.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) Auto_anti-p27 PF06677.7 EDN96839.1 - 0.3 10.8 0.1 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SH3_2 PF07653.12 EDN96840.1 - 0.00014 21.2 0.1 1.7 8.2 0.0 4.2 4 1 0 4 4 4 2 Variant SH3 domain Rad9_Rad53_bind PF08605.5 EDN96840.1 - 0.0021 17.8 0.0 1.4 8.6 0.0 4.2 5 0 0 5 5 5 1 Fungal Rad9-like Rad53-binding Peptidase_A4 PF01828.12 EDN96840.1 - 0.0075 15.3 5.2 0.39 9.7 0.0 4.7 6 0 0 6 6 6 1 Peptidase A4 family SH3_1 PF00018.23 EDN96840.1 - 0.0085 15.4 0.1 44 3.5 0.0 4.9 6 0 0 6 6 6 0 SH3 domain ALS2CR8 PF15299.1 EDN96840.1 - 0.018 14.6 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Molybdopterin PF00384.17 EDN96841.1 - 1.3e-74 251.4 0.0 1.7e-72 244.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EDN96841.1 - 5.4e-19 67.1 0.1 1.3e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EDN96841.1 - 1.3e-18 66.5 0.4 3.6e-18 65.1 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EDN96841.1 - 3.4e-15 55.9 0.0 7.7e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 EDN96841.1 - 0.00024 20.8 0.1 0.046 13.4 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fer2 PF00111.22 EDN96841.1 - 0.0003 20.4 0.3 0.0003 20.4 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain ER_lumen_recept PF00810.13 EDN96842.1 - 9e-54 181.9 6.6 1.5e-53 181.2 4.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EDN96842.1 - 0.032 13.7 11.4 0.56 9.7 0.2 4.1 2 1 2 4 4 4 0 PQ loop repeat WLM PF08325.5 EDN96843.1 - 2.6e-46 157.8 0.0 3.9e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.4 EDN96843.1 - 0.00042 20.0 0.1 0.0007 19.2 0.1 1.4 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 EDN96843.1 - 0.0024 17.7 0.1 0.0051 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 ubiquitin PF00240.18 EDN96843.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family F-box PF00646.28 EDN96844.1 - 0.073 12.7 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 F-box domain DUF1889 PF08986.5 EDN96844.1 - 0.1 12.7 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) zf-RanBP PF00641.13 EDN96846.1 - 5.8e-20 70.0 8.9 4.3e-11 41.7 0.8 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EDN96846.1 - 5.8e-08 32.2 0.0 1.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN96846.1 - 2e-05 24.5 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EDN96846.1 - 3e-05 24.3 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.1 EDN96846.1 - 1.1 8.5 5.9 9.6 5.5 1.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EDN96846.1 - 1.3 8.8 8.5 1 9.2 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon Alpha-amylase PF00128.19 EDN96850.1 - 1.1e-47 162.9 0.2 1.2e-33 116.8 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN96850.1 - 1.4e-31 108.4 0.9 4.2e-31 106.8 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Atu4866 PF11512.3 EDN96850.1 - 0.11 12.1 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Agrobacterium tumefaciens protein Atu4866 DDE_1 PF03184.14 EDN96851.1 - 4.6e-50 169.7 0.1 9.3e-50 168.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN96851.1 - 2e-05 24.3 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN96851.1 - 0.79 9.7 12.9 0.041 13.8 5.1 1.8 2 0 0 2 2 2 0 Zinc knuckle SPC22 PF04573.7 EDN96852.1 - 2e-32 111.8 0.8 1e-23 83.4 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit DUF2671 PF10877.3 EDN96852.1 - 0.098 12.4 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) Pmp3 PF01679.12 EDN96853.1 - 1.8e-19 69.1 9.7 2.2e-19 68.8 6.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Carboxyl_trans PF01039.17 EDN96854.1 - 1.6e-79 267.5 0.0 2.1e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain HJURP_C PF12347.3 EDN96854.1 - 0.029 13.9 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat CPSase_L_D2 PF02786.12 EDN96855.1 - 1.6e-35 122.2 0.0 2.4e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EDN96855.1 - 4.8e-27 94.0 0.0 8.9e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EDN96855.1 - 1.9e-11 43.3 0.3 4e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EDN96855.1 - 1.3e-10 41.2 0.1 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN96855.1 - 9.7e-09 34.9 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDN96855.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDN96855.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EDN96855.1 - 0.044 12.9 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein ATPgrasp_Ter PF15632.1 EDN96855.1 - 0.061 12.0 0.0 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.1 EDN96855.1 - 0.064 12.3 0.1 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.11 EDN96855.1 - 0.098 11.7 0.1 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 EDN96855.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDN96855.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like Corona_nucleoca PF00937.13 EDN96857.1 - 3.7 6.3 8.0 5.4 5.8 5.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein WW PF00397.21 EDN96858.1 - 2.6e-06 27.1 2.5 6.6e-06 25.8 1.7 1.7 1 0 0 1 1 1 1 WW domain Selenoprotein_S PF06936.6 EDN96858.1 - 0.2 11.1 5.5 0.41 10.1 3.8 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Metallophos PF00149.23 EDN96862.1 - 3.8e-42 143.9 0.9 5.6e-42 143.4 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase bZIP_2 PF07716.10 EDN96864.1 - 0.00089 19.0 8.0 0.00089 19.0 5.6 2.2 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN96864.1 - 0.052 13.5 6.6 0.67 9.9 4.4 2.2 1 1 0 1 1 1 0 bZIP transcription factor Voldacs PF03517.8 EDN96865.1 - 3e-24 85.4 0.0 6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling ketoacyl-synt PF00109.21 EDN96866.1 - 2.8e-72 243.2 0.0 5.6e-72 242.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDN96866.1 - 1.1e-54 185.9 0.1 5.1e-54 183.7 0.1 2.0 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EDN96866.1 - 2.7e-43 148.2 0.0 4.2e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EDN96866.1 - 4.8e-42 143.6 0.6 5.2e-25 88.1 0.0 3.2 2 1 1 3 3 3 2 KR domain Ketoacyl-synt_C PF02801.17 EDN96866.1 - 1.1e-37 128.4 0.1 3.8e-37 126.7 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDN96866.1 - 2.7e-30 105.4 0.3 2.9e-17 63.0 0.0 3.6 2 1 1 3 3 3 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EDN96866.1 - 2.8e-18 66.2 0.0 7.9e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EDN96866.1 - 4.1e-12 45.7 0.0 2e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EDN96866.1 - 1.3e-11 44.5 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN96866.1 - 3.1e-10 40.6 0.0 1.2e-09 38.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN96866.1 - 7.2e-09 35.3 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN96866.1 - 1.2e-06 28.9 0.0 8.5e-06 26.1 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EDN96866.1 - 1.7e-06 28.1 0.0 4.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EDN96866.1 - 0.0001 22.6 0.0 0.00066 19.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN96866.1 - 0.00032 19.8 0.0 0.001 18.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EDN96866.1 - 0.00044 19.3 0.1 0.00097 18.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 EDN96866.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EDN96866.1 - 0.1 12.6 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EDN96867.1 - 2.3e-15 57.0 0.1 3.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN96867.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 EDN96870.1 - 0.068 12.1 0.0 2.9 6.7 0.0 2.0 1 1 1 2 2 2 0 Aminotransferase class I and II Pyr_redox_2 PF07992.9 EDN96871.1 - 5.2e-16 59.1 0.0 1.3e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN96871.1 - 2.6e-10 40.5 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN96871.1 - 9.6e-06 24.7 0.0 8.4e-05 21.6 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDN96871.1 - 2.4e-05 24.4 0.1 0.00026 21.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN96871.1 - 0.015 13.9 0.2 2.9 6.4 0.0 2.5 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EDN96871.1 - 0.016 15.4 0.0 0.07 13.3 0.0 2.0 3 0 0 3 3 3 0 Putative NAD(P)-binding DAO PF01266.19 EDN96871.1 - 0.02 13.8 0.1 2.1 7.1 0.2 3.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN96871.1 - 0.15 11.8 1.1 4.5 7.0 0.0 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding Acetyltransf_1 PF00583.19 EDN96872.1 - 8.6e-13 48.1 0.1 1.3e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN96872.1 - 3.5e-08 33.4 0.2 5.8e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN96872.1 - 9.2e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN96872.1 - 0.00033 20.7 0.1 0.00049 20.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN96872.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4434 PF14488.1 EDN96872.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Melibiase PF02065.13 EDN96873.1 - 4.3e-12 45.4 0.0 4.3e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EDN96873.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Sugar_tr PF00083.19 EDN96874.1 - 1.4e-78 264.4 28.8 1.6e-78 264.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN96874.1 - 9.3e-19 67.3 40.2 8.2e-14 51.0 21.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN96874.1 - 0.001 17.5 33.8 0.0031 15.9 2.1 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein Aa_trans PF01490.13 EDN96876.1 - 5.1e-47 160.2 38.9 6.1e-47 160.0 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EDN96876.1 - 1.4e-07 30.7 19.2 2.7e-07 29.7 13.3 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family rve PF00665.21 EDN96877.1 - 2.9e-08 33.8 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN96877.1 - 8.7e-05 22.0 0.3 0.00026 20.5 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN96877.1 - 0.032 13.9 0.2 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) HTH_Tnp_Tc5 PF03221.11 EDN96878.1 - 0.0032 17.2 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain ketoacyl-synt PF00109.21 EDN96879.1 - 1.1e-77 260.9 0.0 1.9e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 EDN96879.1 - 7.6e-72 242.2 0.0 1.7e-43 148.6 0.0 2.2 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase KR PF08659.5 EDN96879.1 - 8.2e-51 172.2 0.1 2e-50 170.9 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EDN96879.1 - 2.4e-46 158.2 0.0 4.1e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EDN96879.1 - 7.1e-39 133.3 0.1 7.1e-39 133.3 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDN96879.1 - 2.2e-37 127.5 0.1 5.5e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EDN96879.1 - 7e-20 71.3 0.0 2.8e-19 69.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EDN96879.1 - 4.6e-18 65.0 0.0 4.6e-17 61.7 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.16 EDN96879.1 - 4.6e-17 62.3 2.0 4e-12 46.0 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_23 PF13489.1 EDN96879.1 - 1.2e-11 44.6 0.0 3.7e-11 42.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EDN96879.1 - 1.6e-09 38.7 0.0 7e-09 36.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EDN96879.1 - 4.7e-08 33.4 0.0 1.7e-07 31.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN96879.1 - 1.9e-07 31.6 0.0 5.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN96879.1 - 4.6e-07 29.5 0.0 1.7e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EDN96879.1 - 5.2e-07 29.4 0.2 1.2e-06 28.1 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EDN96879.1 - 9.7e-07 28.9 0.1 2.7e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EDN96879.1 - 1.9e-05 24.1 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN96879.1 - 2.7e-05 23.0 0.1 4.9e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 EDN96879.1 - 0.00018 20.7 0.0 0.00045 19.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EDN96879.1 - 0.0017 18.6 0.0 0.008 16.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EDN96879.1 - 0.0031 17.5 1.7 0.59 10.1 0.0 3.4 3 0 0 3 3 3 1 NADH(P)-binding Thiolase_N PF00108.18 EDN96879.1 - 0.0058 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 EDN96879.1 - 0.011 15.8 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GYD PF08734.6 EDN96879.1 - 0.13 12.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 GYD domain PLDc_2 PF13091.1 EDN96881.1 - 3e-14 52.8 0.0 6.1e-06 26.0 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EDN96881.1 - 7.9e-13 47.7 0.9 6e-05 22.7 0.0 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif GMC_oxred_N PF00732.14 EDN96883.1 - 6.7e-50 169.9 0.1 6.9e-30 104.2 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN96883.1 - 9.4e-22 77.8 0.0 1.8e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN96883.1 - 1.3e-07 30.8 0.1 0.002 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN96883.1 - 1e-05 24.6 0.1 0.026 13.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN96883.1 - 0.0035 17.3 0.1 0.0081 16.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN96883.1 - 0.017 14.0 0.1 0.043 12.7 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EDN96883.1 - 0.02 14.7 0.2 7.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN96883.1 - 0.022 14.8 0.1 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN96883.1 - 0.04 13.0 0.1 0.095 11.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EDN96883.1 - 0.13 11.9 0.1 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding ADH_N PF08240.7 EDN96884.1 - 1.5e-09 37.5 0.0 3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN96884.1 - 9e-07 28.5 0.1 1.7e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQ-loop PF04193.9 EDN96886.1 - 2.7e-16 58.8 0.6 2.7e-16 58.8 0.4 2.0 2 0 0 2 2 2 1 PQ loop repeat DUF3537 PF12056.3 EDN96886.1 - 0.16 10.6 0.7 0.26 9.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) zf-GRF PF06839.7 EDN96887.1 - 3.8e-11 42.7 3.3 7.5e-11 41.7 2.3 1.4 1 0 0 1 1 1 1 GRF zinc finger TMF_DNA_bd PF12329.3 EDN96887.1 - 0.00026 20.7 0.9 0.00026 20.7 0.6 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding BMFP PF04380.8 EDN96887.1 - 0.4 10.8 7.1 1.8 8.7 1.7 3.3 3 1 0 3 3 3 0 Membrane fusogenic activity GATase_5 PF13507.1 EDN96888.1 - 7.7e-99 329.7 0.0 1.1e-98 329.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EDN96888.1 - 2e-43 148.0 0.1 1.4e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EDN96888.1 - 5.8e-25 87.3 0.9 5.3e-24 84.2 0.0 3.0 4 0 0 4 4 4 1 AIR synthase related protein, N-terminal domain DUF3378 PF11858.3 EDN96888.1 - 0.18 11.8 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) DUF2206 PF09971.4 EDN96889.1 - 0.014 14.2 0.2 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Tubulin PF00091.20 EDN96890.1 - 7.6e-66 222.0 0.0 1e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN96890.1 - 2.4e-42 143.9 0.0 3.7e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN96890.1 - 0.004 16.6 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4187 PF13821.1 EDN96891.1 - 8.9e-24 82.8 0.0 2.2e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EDN96891.1 - 1.9e-23 82.5 1.1 7.1e-23 80.7 0.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EDN96891.1 - 2.1e-08 34.6 0.5 4.9e-08 33.4 0.4 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 TspO_MBR PF03073.10 EDN96892.1 - 2.1e-42 144.1 8.9 2.9e-42 143.6 6.2 1.2 1 0 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.22 EDN96893.1 - 7.4e-63 208.2 0.7 2.5e-21 75.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 EDN96894.1 - 5.8e-39 132.6 27.5 6.8e-39 132.4 19.0 1.0 1 0 0 1 1 1 1 Cgr1 family SprA-related PF12118.3 EDN96894.1 - 0.1 11.8 12.9 0.12 11.7 8.9 1.0 1 0 0 1 1 1 0 SprA-related family PRP1_N PF06424.7 EDN96894.1 - 0.12 12.6 8.8 0.13 12.5 6.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Calc_CGRP_IAPP PF00214.14 EDN96894.1 - 0.6 10.1 4.1 0.94 9.5 2.8 1.5 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family GAGA_bind PF06217.7 EDN96894.1 - 0.7 9.7 13.7 0.8 9.6 9.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Acyl-thio_N PF12590.3 EDN96894.1 - 2.8 8.4 5.6 1.2 9.5 2.3 1.5 1 1 0 1 1 1 0 Acyl-ATP thioesterase Adeno_VII PF03228.9 EDN96894.1 - 4.2 7.9 11.6 5.7 7.5 8.1 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII HrpB7 PF09486.5 EDN96895.1 - 0.019 14.8 1.1 0.035 14.0 0.7 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.6 EDN96895.1 - 0.023 13.3 1.6 0.035 12.7 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BatA PF07584.6 EDN96895.1 - 0.031 14.4 0.2 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF2951 PF11166.3 EDN96895.1 - 0.038 13.8 4.3 0.039 13.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) PEARLI-4 PF05278.7 EDN96895.1 - 0.048 13.0 2.8 0.092 12.1 2.0 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Hemerythrin PF01814.18 EDN96895.1 - 0.057 13.5 1.9 3.6 7.7 0.5 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Fib_alpha PF08702.5 EDN96895.1 - 0.058 13.5 0.6 0.19 11.8 0.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rrn6 PF10214.4 EDN96895.1 - 0.064 11.3 0.1 0.066 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PDDEXK_1 PF12705.2 EDN96895.1 - 0.076 12.3 0.4 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF2116 PF09889.4 EDN96895.1 - 0.085 12.6 0.4 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Syntaxin-6_N PF09177.6 EDN96895.1 - 0.088 13.2 2.2 0.59 10.5 0.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Peroxin-13_N PF04088.8 EDN96895.1 - 0.12 12.3 0.5 0.94 9.4 0.0 2.4 2 1 1 3 3 3 0 Peroxin 13, N-terminal region SlyX PF04102.7 EDN96895.1 - 0.99 9.8 4.0 0.76 10.1 0.1 2.7 2 1 2 4 4 4 0 SlyX DUF3818 PF12825.2 EDN96896.1 - 1.5e-138 461.1 3.8 2.3e-138 460.5 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDN96896.1 - 4.8e-43 146.0 0.9 1e-42 144.9 0.6 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EDN96896.1 - 3.1e-13 49.5 1.1 2.6e-12 46.5 0.0 3.2 4 1 0 4 4 4 1 PX domain Myc_N PF01056.13 EDN96896.1 - 0.024 13.7 1.3 0.044 12.9 0.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Methyltransf_32 PF13679.1 EDN96897.1 - 5.2e-18 65.0 0.0 4.2e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Cpn60_TCP1 PF00118.19 EDN96898.1 - 3.9e-138 461.1 14.9 4.9e-138 460.7 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EDN96898.1 - 0.03 13.7 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 EDN96899.1 - 2.4e-40 137.7 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN96899.1 - 4.8e-06 26.7 0.0 0.00061 19.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN96899.1 - 4.5e-05 23.2 0.1 0.00028 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN96899.1 - 0.00031 20.7 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN96899.1 - 0.00031 20.7 0.1 0.0016 18.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EDN96899.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDN96899.1 - 0.0041 17.9 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN96899.1 - 0.0075 15.9 0.2 0.021 14.5 0.1 1.7 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EDN96899.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDN96899.1 - 0.016 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN96899.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN96899.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN96899.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EDN96899.1 - 0.046 13.2 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EDN96899.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDN96899.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EDN96899.1 - 0.089 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EDN96899.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDN96899.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EDN96899.1 - 0.15 11.4 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Glyco_hydro_45 PF02015.11 EDN96900.1 - 8e-81 270.9 22.6 8e-81 270.9 15.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EDN96900.1 - 2.8e-12 46.0 10.2 2.8e-12 46.0 7.1 3.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Ribonuc_L-PSP PF01042.16 EDN96902.1 - 1.7e-34 118.1 0.0 2.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.13 EDN96903.1 - 2.9e-79 265.8 17.8 2.9e-79 265.8 12.3 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDN96903.1 - 4.1e-19 68.8 0.1 1.1e-18 67.4 0.0 1.7 1 1 1 2 2 2 2 MIR domain NAD_binding_10 PF13460.1 EDN96904.1 - 5.5e-28 98.2 0.0 6.3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN96904.1 - 1.6e-05 24.4 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EDN96904.1 - 9e-05 21.8 0.1 0.00015 21.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EDN96904.1 - 0.0042 17.0 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 EDN96904.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_43 PF04616.9 EDN96905.1 - 1.4e-31 109.6 3.5 1.1e-30 106.7 2.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF544 PF04424.8 EDN96906.1 - 1.3e-12 47.6 0.0 2.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EDN96907.1 - 3.7e-76 256.1 0.0 5e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 EDN96908.1 - 1.1e-81 272.7 0.0 1.2e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Isochorismatase PF00857.15 EDN96909.1 - 7.7e-20 71.5 0.0 8.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_61 PF03443.9 EDN96910.1 - 1.5e-80 270.0 0.2 1.8e-80 269.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.1 EDN96910.1 - 0.026 14.8 5.1 0.11 12.8 0.3 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) NPCBM_assoc PF10633.4 EDN96910.1 - 0.039 14.0 2.4 0.5 10.4 0.0 3.0 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Methyltransf_11 PF08241.7 EDN96912.1 - 2.1e-09 37.7 0.0 3.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN96912.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDN96912.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EDN96915.1 - 1.9e-83 280.5 0.0 2.7e-82 276.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ribul_P_3_epim PF00834.14 EDN96916.1 - 1.5e-63 213.5 0.0 1.5e-62 210.3 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EDN96916.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 EDN96916.1 - 0.062 12.5 0.2 0.15 11.3 0.1 1.7 1 1 0 1 1 1 0 PcrB family ThiG PF05690.9 EDN96916.1 - 0.098 11.7 0.1 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Phosphodiest PF01663.17 EDN96916.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase QRPTase_C PF01729.14 EDN96916.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Amidohydro_2 PF04909.9 EDN96916.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.6 1 1 1 2 2 2 0 Amidohydrolase Aminotran_5 PF00266.14 EDN96918.1 - 1.7e-56 191.6 0.0 2.1e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDN96918.1 - 2.6e-05 23.3 0.0 6.4e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDN96918.1 - 0.00045 18.6 0.0 0.00079 17.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ofd1_CTDD PF10637.4 EDN96919.1 - 2.2e-103 345.0 5.3 5.6e-97 324.0 3.4 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EDN96919.1 - 9.9e-16 58.0 0.0 2.3e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TFIIA PF03153.8 EDN96920.1 - 0.0041 17.0 18.1 0.0064 16.4 12.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ChlamPMP_M PF07548.6 EDN96920.1 - 0.048 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Abhydrolase_3 PF07859.8 EDN96921.1 - 1.4e-35 122.7 0.0 4.9e-35 121.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN96921.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EDN96921.1 - 0.17 10.4 0.0 9.2 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Pkinase PF00069.20 EDN96922.1 - 6e-69 232.0 0.0 8.5e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN96922.1 - 2.9e-30 105.2 0.0 4.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDN96922.1 - 2.2e-09 37.2 0.4 1.6e-07 31.3 0.1 2.6 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EDN96922.1 - 5.8e-05 22.1 0.0 0.0012 17.9 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN96922.1 - 0.0037 16.3 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GPI-anchored PF10342.4 EDN96923.1 - 3.4e-20 72.2 3.5 3.4e-20 72.2 2.4 3.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hex_IIIa PF02455.11 EDN96923.1 - 1.5 7.4 11.5 2.3 6.8 8.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Macoilin PF09726.4 EDN96923.1 - 6.4 4.9 35.4 8.4 4.5 24.5 1.1 1 0 0 1 1 1 0 Transmembrane protein STT3 PF02516.9 EDN96926.1 - 1.3e-100 337.6 29.4 8.6e-96 321.7 19.3 2.2 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.7 EDN96927.1 - 7.4e-25 86.7 0.1 7.7e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 EDN96928.1 - 7e-20 70.1 3.9 3.9e-07 29.6 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Dynein_IC2 PF11540.3 EDN96928.1 - 0.14 11.5 1.9 0.98 8.8 0.8 2.5 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 UCH PF00443.24 EDN96929.1 - 7.3e-33 113.8 0.0 1.1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN96929.1 - 1.7e-21 76.9 0.0 5.9e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_Zc3h12a_2 PF14626.1 EDN96929.1 - 0.11 12.3 0.1 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain PSCyt2 PF07583.6 EDN96929.1 - 0.16 11.4 0.1 0.48 9.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Methyltransf_11 PF08241.7 EDN96930.1 - 9.7e-11 42.0 0.0 1.6e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN96930.1 - 6.6e-09 35.6 0.0 9.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN96930.1 - 9.4e-07 29.1 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN96930.1 - 5.5e-06 26.7 0.0 9.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN96930.1 - 3.7e-05 23.3 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN96930.1 - 0.00058 20.4 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EDN96930.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.26 EDN96931.1 - 3.9e-11 42.8 2.0 1.3e-08 34.7 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN96931.1 - 7.4e-07 29.1 5.3 0.00097 19.1 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EDN96933.1 - 1.9e-20 72.2 3.5 2.8e-20 71.7 2.4 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EDN96933.1 - 8.8e-16 57.9 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EDN96933.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Aldo_ket_red PF00248.16 EDN96934.1 - 2e-08 33.4 0.2 3e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 EDN96935.1 - 2e-19 70.2 0.2 3.5e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EDN96935.1 - 0.031 14.6 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain zf-RING_2 PF13639.1 EDN96938.1 - 6.1e-14 51.5 6.0 1e-13 50.8 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN96938.1 - 2.2e-08 34.1 0.6 3.9e-08 33.2 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN96938.1 - 8.8e-07 28.4 3.9 1.5e-06 27.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN96938.1 - 7.1e-06 25.9 5.2 1.1e-05 25.2 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN96938.1 - 8.3e-06 25.4 4.1 1.3e-05 24.7 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN96938.1 - 5.9e-05 22.6 2.3 0.0001 21.8 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN96938.1 - 0.002 17.9 1.2 0.0044 16.8 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDN96938.1 - 0.0068 15.9 2.8 0.011 15.3 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 EDN96938.1 - 0.047 13.8 1.0 0.061 13.4 0.1 1.7 2 0 0 2 2 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EDN96938.1 - 0.052 13.5 0.2 0.097 12.6 0.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EDN96938.1 - 0.35 10.9 3.1 0.58 10.2 2.2 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EDN96938.1 - 0.9 9.2 5.0 2.2 8.0 3.4 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EDN96938.1 - 2.2 8.0 6.3 9.9 5.9 4.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EDN96938.1 - 6.5 6.7 7.6 13 5.8 3.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Ribosomal_L27 PF01016.14 EDN96940.1 - 1.8e-28 98.1 0.1 3.1e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rhodanese PF00581.15 EDN96943.1 - 1.1e-12 48.2 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.12 EDN96944.1 - 2.6e-12 46.5 17.7 3.6e-12 46.1 12.1 1.4 1 1 0 1 1 1 1 Yip1 domain TPIP1 PF15338.1 EDN96944.1 - 0.073 12.9 0.3 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 ubiquitin PF00240.18 EDN96945.1 - 6.2e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EDN96945.1 - 3e-30 103.5 10.2 4.8e-30 102.9 7.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EDN96945.1 - 6.1e-20 70.6 0.7 8.8e-20 70.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN96945.1 - 8.4e-06 25.9 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN96945.1 - 0.00017 21.3 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN96945.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN96945.1 - 0.013 15.6 0.1 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDN96945.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) eIF-5a PF01287.15 EDN96946.1 - 1.2e-24 86.0 0.7 1.7e-24 85.5 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EDN96946.1 - 0.00029 20.4 0.5 0.00057 19.4 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EDN96946.1 - 0.019 14.8 0.1 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EDN96947.1 - 1.5e-125 419.6 1.2 2e-125 419.2 0.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EDN96947.1 - 0.00014 20.1 3.1 0.00021 19.6 2.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 EDN96947.1 - 0.01 15.7 1.4 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 Mer2 Reo_sigmaC PF04582.7 EDN96947.1 - 0.11 11.6 0.3 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RabGAP-TBC PF00566.13 EDN96948.1 - 0.033 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain MMS1_N PF10433.4 EDN96949.1 - 1.2e-123 412.9 0.0 4.9e-123 410.9 0.0 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 EDN96950.1 - 1.5e-31 109.3 0.0 1.5e-31 109.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EDN96950.1 - 5.2e-08 32.8 0.9 1.4e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN96950.1 - 3.3e-06 27.0 0.0 8.6e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EDN96950.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EDN96950.1 - 0.0045 17.4 0.0 0.02 15.3 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDN96950.1 - 0.019 14.3 0.0 0.094 12.0 0.0 2.3 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.1 EDN96950.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain GTP_EFTU_D4 PF14578.1 EDN96951.1 - 0.0044 16.6 0.4 0.0097 15.5 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Arteri_env PF01606.11 EDN96951.1 - 0.056 13.0 0.0 4.6 6.8 0.0 2.2 1 1 1 2 2 2 0 Arterivirus envelope protein DNA_pol_phi PF04931.8 EDN96952.1 - 0.0036 15.1 1.6 0.0063 14.3 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase phi DNA_pol_phi PF04931.8 EDN96953.1 - 2.2e-08 32.3 41.9 5.3e-08 31.1 29.1 1.6 1 1 0 1 1 1 1 DNA polymerase phi Daxx PF03344.10 EDN96953.1 - 0.063 11.7 16.9 0.083 11.3 11.7 1.3 1 0 0 1 1 1 0 Daxx Family Med23 PF11573.3 EDN96953.1 - 0.073 10.3 1.1 2.8 5.1 0.1 2.0 1 1 1 2 2 2 0 Mediator complex subunit 23 TFIIF_alpha PF05793.7 EDN96953.1 - 0.18 10.1 24.2 0.23 9.7 16.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1676 PF07898.8 EDN96953.1 - 1 9.7 5.7 1.4 9.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Cutinase PF01083.17 EDN96954.1 - 1.4e-11 44.4 0.1 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF1614 PF07758.6 EDN96954.1 - 0.15 11.7 0.6 0.19 11.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) PPR_2 PF13041.1 EDN96955.1 - 3.1e-16 59.0 7.8 2.6e-09 36.9 0.2 7.0 6 2 3 9 9 9 4 PPR repeat family PPR_3 PF13812.1 EDN96955.1 - 1.2e-14 53.2 18.6 0.027 14.7 0.0 10.5 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR PF01535.15 EDN96955.1 - 2.3e-12 45.9 13.7 0.044 13.7 0.0 10.1 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 EDN96955.1 - 1.2e-06 27.8 0.0 0.0057 16.1 0.0 3.3 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.1 EDN96955.1 - 3.2e-05 24.1 0.0 5.1 7.5 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN96955.1 - 8.1e-05 22.9 5.8 17 6.3 0.0 7.5 10 0 0 10 10 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN96955.1 - 0.0034 17.4 0.2 2.8 8.1 0.1 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Sec7 PF01369.15 EDN96955.1 - 0.014 15.0 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Sec7 domain HLH PF00010.21 EDN96955.1 - 0.027 14.1 0.2 0.081 12.6 0.2 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Cytidylate_kin PF02224.13 EDN96955.1 - 0.065 12.6 0.2 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase TPR_10 PF13374.1 EDN96955.1 - 0.83 9.6 4.5 7.2 6.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Mo-co_dimer PF03404.11 EDN96957.1 - 5.2e-55 184.6 0.3 5.2e-55 184.6 0.2 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EDN96957.1 - 3.5e-49 166.4 0.0 6.2e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EDN96957.1 - 6.6e-30 103.1 0.0 1.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EDN96957.1 - 9.9e-25 86.1 0.0 4e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EDN96957.1 - 3.6e-21 75.7 0.0 7.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDN96957.1 - 0.00015 21.6 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MIF4G PF02854.14 EDN96959.1 - 1.9e-60 203.8 0.0 8.5e-30 103.7 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EDN96959.1 - 4.1e-58 195.9 12.8 4.1e-58 195.9 8.8 3.1 3 0 0 3 3 3 1 Up-frameshift suppressor 2 HSP70 PF00012.15 EDN96960.1 - 1.8e-169 564.4 0.2 1.8e-169 564.4 0.2 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDN96960.1 - 2.7e-13 49.2 0.1 7e-12 44.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EDN96960.1 - 0.0069 16.2 3.3 0.35 10.7 0.0 3.2 3 2 0 3 3 3 2 Cell division protein FtsA IncA PF04156.9 EDN96960.1 - 1.6 8.3 6.6 3 7.3 4.6 1.4 1 0 0 1 1 1 0 IncA protein Chitin_synth_2 PF03142.10 EDN96961.1 - 1.7e-26 92.7 4.2 2.3e-23 82.3 1.8 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EDN96961.1 - 3.8e-17 62.8 0.0 7.2e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDN96961.1 - 7.9e-17 61.5 4.2 7.9e-17 61.5 2.9 2.4 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EDN96961.1 - 0.0067 16.1 0.1 4.2 7.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF4210 PF13915.1 EDN96964.1 - 1e-25 89.7 0.0 1.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EDN96964.1 - 1.5e-19 69.5 0.6 2.9e-19 68.7 0.4 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 EDN96967.1 - 0.0015 18.3 34.9 0.0031 17.2 9.8 2.2 1 1 1 2 2 2 2 rRNA processing Myb_DNA-bind_6 PF13921.1 EDN96970.1 - 0.00025 21.0 0.1 0.0072 16.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN96970.1 - 0.0026 17.7 0.1 0.0086 16.1 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 EDN96970.1 - 0.032 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1616 PF07760.6 EDN96971.1 - 0.096 11.8 0.2 0.096 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) TatD_DNase PF01026.16 EDN96972.1 - 1.2e-30 106.5 0.0 1.9e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Adeno_PVIII PF01310.13 EDN96972.1 - 0.071 12.9 0.0 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII Spc24 PF08286.6 EDN96974.1 - 7.6e-40 135.2 3.8 3.2e-39 133.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EDN96974.1 - 0.0043 16.7 2.5 0.18 11.5 0.7 2.3 2 0 0 2 2 2 1 Prefoldin subunit DUF342 PF03961.8 EDN96974.1 - 0.0063 14.9 1.8 0.0076 14.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) HOOK PF05622.7 EDN96974.1 - 0.012 13.5 3.5 0.015 13.1 2.4 1.1 1 0 0 1 1 1 0 HOOK protein Reo_sigmaC PF04582.7 EDN96974.1 - 0.013 14.6 1.8 0.017 14.3 1.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 EDN96974.1 - 0.015 14.3 5.1 0.02 13.9 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4613 PF15390.1 EDN96974.1 - 0.02 13.0 1.9 0.025 12.7 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) MAGSP PF03082.9 EDN96974.1 - 0.023 14.1 1.8 0.035 13.4 1.3 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein Exonuc_VII_L PF02601.10 EDN96974.1 - 0.028 13.6 1.8 0.032 13.4 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Streptin-Immun PF11083.3 EDN96974.1 - 0.032 14.2 2.2 0.084 12.8 0.1 2.3 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein PGA_cap PF09587.5 EDN96974.1 - 0.04 13.2 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap WXG100 PF06013.7 EDN96974.1 - 0.048 13.6 3.9 0.065 13.2 0.3 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG TBPIP PF07106.8 EDN96974.1 - 0.055 13.0 5.3 0.051 13.1 1.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glyco_hydro_4C PF11975.3 EDN96974.1 - 0.095 12.4 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain V_ATPase_I PF01496.14 EDN96974.1 - 0.11 10.3 0.9 0.11 10.2 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dad1 PF08649.5 EDN96974.1 - 0.13 11.9 0.7 0.25 11.0 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 MT PF12777.2 EDN96974.1 - 0.21 10.2 1.8 0.28 9.9 0.3 1.7 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor DUF724 PF05266.9 EDN96974.1 - 0.38 10.3 4.1 7.1 6.2 2.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) AATF-Che1 PF13339.1 EDN96974.1 - 1.1 9.4 5.7 0.66 10.1 0.5 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4164 PF13747.1 EDN96974.1 - 1.2 9.3 11.1 1.6 8.9 5.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Viral_P18 PF04521.8 EDN96974.1 - 1.5 8.3 4.7 5 6.5 0.5 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DASH_Hsk3 PF08227.6 EDN96974.1 - 1.5 9.0 11.3 0.99 9.6 1.7 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like FlxA PF14282.1 EDN96974.1 - 2.4 8.1 9.4 3.6 7.5 2.4 2.4 1 1 1 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 EDN96974.1 - 2.5 8.0 4.4 14 5.6 0.2 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EDN96974.1 - 2.8 7.4 11.7 13 5.3 8.1 1.8 1 1 0 1 1 1 0 IncA protein PEP-utilisers_N PF05524.8 EDN96974.1 - 2.9 7.7 6.6 3.6 7.4 1.5 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Fis1_TPR_C PF14853.1 EDN96975.1 - 1.5e-26 92.0 1.2 2.5e-26 91.2 0.9 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EDN96975.1 - 1.7e-18 65.6 0.0 3.4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EDN96975.1 - 0.0013 18.5 1.3 0.0028 17.4 0.9 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN96975.1 - 0.024 15.3 0.5 0.046 14.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN96975.1 - 0.075 13.5 1.2 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN96975.1 - 0.076 13.3 0.7 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EDN96976.1 - 1.3e-14 53.7 6.1 1.3e-14 53.7 4.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN96976.1 - 2.2e-11 43.2 2.2 2.2e-11 43.2 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN96976.1 - 3.1e-08 33.4 6.1 3.1e-08 33.4 4.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN96976.1 - 6.8e-07 29.3 2.9 1.3e-06 28.3 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDN96976.1 - 2.6e-06 27.0 3.8 2.6e-06 27.0 2.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN96976.1 - 4.5e-05 23.0 7.9 6.9e-05 22.4 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN96976.1 - 0.0011 18.7 1.3 0.002 17.9 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EDN96976.1 - 0.0092 15.5 2.4 0.018 14.6 1.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PHD PF00628.24 EDN96976.1 - 0.57 9.9 8.5 2.6 7.7 3.2 2.5 2 0 0 2 2 2 0 PHD-finger Fungal_trans PF04082.13 EDN96977.1 - 3.1e-24 85.2 0.6 4.5e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN96977.1 - 6.3e-08 32.4 9.3 1.1e-07 31.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EDN96978.1 - 1.6e-10 41.3 0.1 4.9e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN96978.1 - 2.5e-07 30.8 0.0 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN96978.1 - 7.8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDN96978.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN96978.1 - 0.00019 21.1 0.0 0.00054 19.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EDN96978.1 - 0.00089 19.1 0.1 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDN96978.1 - 0.0014 17.4 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDN96978.1 - 0.0017 19.1 0.1 0.015 16.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EDN96978.1 - 0.0027 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDN96978.1 - 0.015 15.0 0.7 0.1 12.3 0.1 2.3 1 1 1 2 2 2 0 NTPase Zeta_toxin PF06414.7 EDN96978.1 - 0.028 13.5 0.0 0.078 12.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EDN96978.1 - 0.029 14.3 0.0 0.24 11.3 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EDN96978.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDN96978.1 - 0.065 13.5 0.1 0.22 11.8 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EDN96978.1 - 0.067 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDN96978.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 EDN96978.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain zf-FPG_IleRS PF06827.9 EDN96980.1 - 0.011 15.3 0.9 0.089 12.4 0.5 2.2 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS DUF4501 PF14946.1 EDN96980.1 - 0.19 11.1 1.0 0.21 11.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) zf-A20 PF01754.11 EDN96980.1 - 0.56 9.8 0.2 0.56 9.8 0.1 2.3 4 0 0 4 4 4 0 A20-like zinc finger DUF2034 PF10356.4 EDN96981.1 - 4.3e-33 114.0 0.0 4.3e-18 65.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EDN96981.1 - 3.2e-07 30.1 0.0 4.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 EDN96982.1 - 6.9e-47 159.0 6.1 8e-47 158.8 4.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Orbi_VP5 PF00901.12 EDN96982.1 - 0.0049 15.1 1.8 0.0065 14.7 1.2 1.3 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 Nop16 PF09420.5 EDN96982.1 - 0.014 15.5 1.8 0.016 15.2 1.2 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Spore_III_AB PF09548.5 EDN96982.1 - 0.056 13.1 2.9 0.06 13.1 1.1 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Macoilin PF09726.4 EDN96982.1 - 0.062 11.5 9.0 0.014 13.6 3.3 1.8 2 0 0 2 2 2 0 Transmembrane protein Med9 PF07544.8 EDN96982.1 - 0.063 13.0 10.4 0.044 13.5 2.4 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4642 PF15484.1 EDN96982.1 - 0.14 12.1 3.6 0.14 12.1 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4642) Fib_alpha PF08702.5 EDN96982.1 - 0.14 12.2 2.4 0.17 12.0 0.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EDN96982.1 - 0.21 10.7 8.8 0.86 8.7 3.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1311 PF07007.7 EDN96982.1 - 0.75 9.9 5.1 2.1 8.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) CENP-Q PF13094.1 EDN96982.1 - 0.78 9.7 12.8 0.12 12.3 6.2 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EDN96982.1 - 0.83 9.5 13.2 0.27 11.0 7.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PhoU PF01895.14 EDN96982.1 - 0.93 9.9 8.1 8 6.9 0.0 2.9 2 1 0 2 2 2 0 PhoU domain IncA PF04156.9 EDN96982.1 - 2.5 7.6 10.6 0.46 10.0 4.1 1.9 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EDN96982.1 - 5 6.0 9.8 0.85 8.6 4.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 HAD_2 PF13419.1 EDN96983.1 - 1.5e-32 113.2 0.3 1.8e-32 112.9 0.2 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN96983.1 - 2.5e-07 30.2 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN96983.1 - 1.4e-05 25.6 0.0 4.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EDN96983.1 - 0.0005 19.7 0.1 0.0027 17.3 0.1 2.0 1 1 0 1 1 1 1 Acid Phosphatase Endonuc-dimeris PF09124.5 EDN96983.1 - 0.002 17.7 0.4 0.0045 16.5 0.3 1.6 1 0 0 1 1 1 1 T4 recombination endonuclease VII, dimerisation KH_3 PF13014.1 EDN96986.1 - 1.3e-24 85.3 6.9 5.7e-05 22.6 0.2 5.7 5 0 0 5 5 5 5 KH domain KH_1 PF00013.24 EDN96986.1 - 5.1e-23 80.4 6.6 1.9e-07 30.5 0.1 7.1 7 0 0 7 7 7 5 KH domain RCC1 PF00415.13 EDN96987.1 - 5.7e-38 128.8 2.0 2e-06 27.9 0.0 7.0 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN96987.1 - 4.6e-24 83.4 21.1 4.2e-08 32.5 0.1 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat HIT PF01230.18 EDN96989.1 - 8.1e-21 74.3 0.0 1.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDN96989.1 - 4.2e-07 30.1 0.0 6.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDN96989.1 - 0.014 15.0 0.8 0.063 12.9 0.5 1.9 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GST_C PF00043.20 EDN96990.1 - 3.8e-14 52.4 0.1 7.3e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN96990.1 - 3.1e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN96990.1 - 4.8e-12 45.8 0.0 9.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN96990.1 - 1.3e-10 41.1 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN96990.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN96990.1 - 3.1e-05 24.3 0.2 4.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Svf1 PF08622.5 EDN96991.1 - 2e-124 414.8 0.0 2.3e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Svf1-like HYR PF02494.11 EDN96991.1 - 0.094 12.7 0.5 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 HYR domain DUF4361 PF14274.1 EDN96991.1 - 0.097 12.3 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) EF-hand_1 PF00036.27 EDN96993.1 - 1.1e-24 83.8 12.0 3.4e-08 32.2 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EDN96993.1 - 1.8e-23 80.2 3.0 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EDN96993.1 - 5.1e-22 77.7 2.2 2.2e-13 50.1 0.1 3.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDN96993.1 - 1.6e-17 61.9 12.9 1.3e-05 24.2 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EDN96993.1 - 3.1e-13 49.1 13.6 1.7e-05 24.3 0.9 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EDN96993.1 - 7.3e-10 38.5 6.1 0.00083 19.0 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EDN96993.1 - 0.00022 21.0 0.3 0.035 14.0 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EDN96993.1 - 0.00062 19.7 1.2 0.19 11.7 0.1 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EDN96993.1 - 0.006 16.2 3.4 0.6 9.8 0.0 3.9 4 0 0 4 4 4 1 EF hand Toprim PF01751.17 EDN96993.1 - 0.012 15.5 0.0 5 7.1 0.0 2.2 1 1 1 2 2 2 0 Toprim domain EF-hand_2 PF09068.6 EDN96993.1 - 0.018 15.1 0.0 2.9 7.9 0.0 3.1 3 1 1 4 4 4 0 EF hand DUF1679 PF07914.6 EDN96993.1 - 0.035 12.7 0.4 1.1 7.7 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EDN96993.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 GST_N_3 PF13417.1 EDN96994.1 - 8.8e-19 67.5 0.1 1.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN96994.1 - 5.5e-15 55.1 0.0 1.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN96994.1 - 1.5e-10 41.1 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EDN96994.1 - 0.026 14.4 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Cation_efflux PF01545.16 EDN96997.1 - 2.7e-19 69.3 0.6 1.2e-17 63.9 0.4 2.0 1 1 0 1 1 1 1 Cation efflux family TPR_11 PF13414.1 EDN96998.1 - 9.5e-08 31.5 3.4 5.2e-05 22.8 0.0 2.6 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN96998.1 - 3.7e-06 26.4 0.8 0.56 10.2 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN96998.1 - 4.9e-05 22.7 2.7 0.5 10.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN96998.1 - 0.0078 16.3 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDN96998.1 - 0.01 16.4 0.3 0.031 14.9 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN96998.1 - 0.015 15.6 0.3 0.04 14.2 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_topoisoIV PF00521.15 EDN97002.1 - 1.1e-126 423.1 0.1 3.4e-126 421.5 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EDN97002.1 - 3.3e-36 124.0 1.9 8e-36 122.8 1.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDN97002.1 - 5e-12 45.6 0.0 3e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EDN97002.1 - 1.1e-09 37.9 0.1 4e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mem_trans PF03547.13 EDN97002.1 - 1.2 7.3 0.6 2 6.6 0.4 1.4 1 0 0 1 1 1 0 Membrane transport protein RabGAP-TBC PF00566.13 EDN97004.1 - 7.1e-47 159.6 0.0 1.5e-46 158.6 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FUSC PF04632.7 EDN97004.1 - 0.18 10.2 1.7 0.33 9.3 1.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fer4_18 PF13746.1 EDN97012.1 - 0.061 13.7 0.5 0.073 13.5 0.4 1.1 1 0 0 1 1 1 0 4Fe-4S dicluster domain Abhydrolase_5 PF12695.2 EDN97013.1 - 6.2e-10 39.0 0.1 1.2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EDN97013.1 - 6.7e-05 22.2 0.3 0.001 18.4 0.1 2.4 1 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EDN97013.1 - 7.1e-05 22.8 0.2 0.001 18.9 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EDN97013.1 - 0.0036 17.0 0.1 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EDN97013.1 - 0.024 13.1 0.1 0.046 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RVT_1 PF00078.22 EDN97015.1 - 8.4e-37 126.5 0.0 1.5e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN97015.1 - 2.7e-11 43.1 0.1 7.7e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN97015.1 - 0.00052 20.0 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PDZ_1 PF12812.2 EDN97016.1 - 4.7e-39 132.1 0.0 1.6e-34 117.6 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EDN97016.1 - 2.2e-14 53.4 0.1 2.2e-13 50.2 0.0 2.4 2 1 1 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EDN97016.1 - 3.1e-11 42.9 0.3 3.3e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.19 EDN97016.1 - 3.6e-07 30.2 0.0 0.0022 18.1 0.0 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EDN97016.1 - 1.7e-05 24.5 0.0 5.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EDN97016.1 - 0.073 12.8 0.2 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EDN97016.1 - 0.099 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF4554 PF15091.1 EDN97016.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF31 PF01732.11 EDN97016.1 - 0.21 10.8 0.2 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) DCX PF03607.12 EDN97018.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Doublecortin Collagen PF01391.13 EDN97020.1 - 2.6e-05 23.6 11.9 2.6e-05 23.6 8.2 1.8 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) CENP-B_dimeris PF09026.5 EDN97020.1 - 0.13 12.5 2.8 0.15 12.2 1.9 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DnaJ PF00226.26 EDN97021.1 - 8.1e-20 70.3 0.6 1.7e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain INCENP_ARK-bind PF03941.10 EDN97023.1 - 7.7e-13 48.0 3.5 3.5e-12 45.9 2.4 2.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Acyl-CoA_dh_1 PF00441.19 EDN97024.1 - 1.5e-29 103.0 1.6 2.2e-29 102.5 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN97024.1 - 1.4e-16 59.7 0.1 3.1e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN97024.1 - 2.9e-15 56.8 0.0 5.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN97024.1 - 3.6e-15 56.3 0.4 6.8e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lipase_GDSL PF00657.17 EDN97025.1 - 1.5e-15 57.6 0.3 1.9e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3969 PF13108.1 EDN97028.1 - 0.019 14.6 0.2 0.039 13.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3969) DUF2422 PF10337.4 EDN97031.1 - 7.7e-31 107.3 9.4 1.8e-14 53.4 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EDN97031.1 - 1.1e-13 51.2 17.8 1.1e-13 51.2 12.3 2.7 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.3 EDN97031.1 - 9.1e-08 31.1 8.6 9.1e-08 31.1 6.0 2.4 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF2421 PF10334.4 EDN97031.1 - 3.7e-05 23.4 0.1 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Ist1 PF03398.9 EDN97032.1 - 1.6e-66 222.7 4.4 2e-66 222.4 3.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway NmrA PF05368.8 EDN97033.1 - 2.4e-05 23.7 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Orthopox_35kD PF02250.10 EDN97035.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 35kD major secreted virus protein Shugoshin_N PF07558.6 EDN97035.1 - 0.12 12.1 1.3 0.26 11.0 0.9 1.6 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DDE_1 PF03184.14 EDN97036.1 - 3.5e-11 42.6 0.0 5.5e-11 42.0 0.0 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease RNA_replicase_B PF03431.8 EDN97036.1 - 0.064 11.4 0.0 0.082 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Epimerase PF01370.16 EDN97037.1 - 3.1e-15 56.2 0.0 4.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN97037.1 - 4e-08 32.4 0.0 1.1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EDN97037.1 - 4.6e-08 32.1 0.0 1e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN97037.1 - 7.5e-05 22.8 0.0 0.00033 20.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EDN97037.1 - 0.0083 15.0 0.3 2.5 6.9 0.0 3.2 2 1 0 3 3 3 1 RmlD substrate binding domain KR PF08659.5 EDN97037.1 - 0.098 12.3 0.2 0.098 12.3 0.1 1.9 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EDN97037.1 - 0.15 11.9 1.6 0.79 9.6 1.1 2.1 1 1 0 1 1 1 0 short chain dehydrogenase DUF515 PF04415.7 EDN97038.1 - 0.2 9.8 14.1 0.26 9.4 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pex14_N PF04695.8 EDN97038.1 - 0.23 11.5 7.3 0.35 10.9 5.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Reticulon PF02453.12 EDN97039.1 - 1.8e-40 138.3 6.4 1.8e-40 138.3 4.4 1.8 2 0 0 2 2 2 1 Reticulon Rotamase PF00639.16 EDN97039.1 - 0.05 14.3 0.3 0.52 11.0 0.0 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain TMEM18 PF14770.1 EDN97039.1 - 0.061 12.8 4.0 3.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Transmembrane protein 18 DUF883 PF05957.8 EDN97039.1 - 0.71 10.3 4.7 0.31 11.4 0.5 2.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1786 PF08735.5 EDN97040.1 - 0.035 13.2 0.6 0.065 12.4 0.1 1.6 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) HET PF06985.6 EDN97041.1 - 1.3e-12 48.1 0.7 2.8e-11 43.7 0.0 2.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Clat_adaptor_s PF01217.15 EDN97042.1 - 1.8e-07 30.9 0.0 1.9e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.1 EDN97043.1 - 1.4e-09 37.3 8.6 0.00022 20.6 1.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EDN97043.1 - 0.00032 20.4 2.4 0.00032 20.4 1.6 2.1 2 0 0 2 2 2 1 Zinc knuckle MAP7 PF05672.6 EDN97043.1 - 0.0023 17.3 1.5 0.0046 16.3 0.1 2.2 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family zf-CCHC_3 PF13917.1 EDN97043.1 - 2.2 8.0 5.4 1.9 8.2 2.5 1.9 1 1 0 1 1 1 0 Zinc knuckle Aminotran_1_2 PF00155.16 EDN97045.1 - 1e-58 199.0 0.0 1.3e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EDN97045.1 - 0.097 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Allinase MmgE_PrpD PF03972.9 EDN97048.1 - 3.6e-84 282.5 1.3 4.4e-43 147.0 0.1 2.0 1 1 1 2 2 2 2 MmgE/PrpD family Peptidase_M1 PF01433.15 EDN97050.1 - 6.2e-118 394.2 0.4 1.1e-117 393.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDN97050.1 - 1.3e-76 257.9 0.0 2e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDN97050.1 - 9.4e-22 77.4 0.4 2.1e-21 76.2 0.3 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily CBFD_NFYB_HMF PF00808.18 EDN97051.1 - 5.7e-05 23.0 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EDN97051.1 - 0.047 13.6 0.3 0.13 12.2 0.2 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W DUF3671 PF12420.3 EDN97051.1 - 0.11 12.4 1.1 0.13 12.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF4404 PF14357.1 EDN97052.1 - 0.71 10.3 7.0 3.3 8.2 4.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) JmjC PF02373.17 EDN97054.1 - 1.9e-39 134.4 0.2 1.9e-39 134.4 0.1 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EDN97054.1 - 8.4e-22 77.2 4.9 1.6e-21 76.3 3.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDN97054.1 - 3.8e-21 75.0 6.4 3.8e-21 75.0 4.4 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EDN97054.1 - 1.6e-13 49.9 0.4 3.2e-13 48.9 0.3 1.6 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.5 EDN97054.1 - 8.4 6.7 12.1 7.4 6.8 4.1 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Excalibur PF05901.6 EDN97055.1 - 0.44 10.9 6.9 14 6.1 0.0 2.1 2 0 0 2 2 2 0 Excalibur calcium-binding domain GMC_oxred_N PF00732.14 EDN97056.1 - 2.3e-60 204.2 0.0 3.9e-60 203.4 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN97056.1 - 1.8e-31 109.3 0.0 3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EDN97056.1 - 0.0048 15.8 0.1 0.0075 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Ras PF00071.17 EDN97057.1 - 1.7e-65 219.3 0.5 1.9e-65 219.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN97057.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN97057.1 - 3.4e-16 58.9 0.1 4e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN97057.1 - 2.2e-05 23.6 0.1 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDN97057.1 - 5.4e-05 22.7 0.2 0.00011 21.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN97057.1 - 6.5e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDN97057.1 - 0.00041 19.6 0.0 0.0006 19.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EDN97057.1 - 0.00053 20.2 0.1 0.092 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN97057.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EDN97057.1 - 0.0048 16.1 0.0 0.033 13.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN97057.1 - 0.0099 15.0 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN97057.1 - 0.013 15.4 0.1 0.083 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EDN97057.1 - 0.029 14.2 0.1 0.09 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDN97057.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDN97057.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EDN97057.1 - 0.076 12.0 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EDN97057.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EDN97057.1 - 0.089 12.2 0.1 0.93 8.9 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SnoaL_2 PF12680.2 EDN97058.1 - 0.093 13.1 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Tom5 PF10642.4 EDN97058.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Helicase_C PF00271.26 EDN97059.1 - 1e-16 60.5 0.0 2.4e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN97059.1 - 4.2e-07 29.6 0.0 2.3e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 EDN97059.1 - 0.083 12.8 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain DUF1256 PF06866.6 EDN97059.1 - 0.099 11.8 0.1 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) Mito_carr PF00153.22 EDN97060.1 - 2.9e-45 151.9 0.5 5.4e-16 58.0 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EDN97060.1 - 0.0052 16.5 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 UcrQ family Abp2 PF09441.5 EDN97061.1 - 1.6e-94 314.7 0.0 2.5e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Oxidored_FMN PF00724.15 EDN97063.1 - 5.3e-99 331.4 0.0 6.8e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UMPH-1 PF05822.7 EDN97063.1 - 0.14 11.4 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) CAP59_mtransfer PF11735.3 EDN97064.1 - 3e-84 282.0 0.0 4.2e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 OppC_N PF12911.2 EDN97066.1 - 0.022 14.1 1.2 0.029 13.7 0.8 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Herpes_UL92 PF03048.9 EDN97066.1 - 0.078 12.5 2.5 0.094 12.2 1.7 1.1 1 0 0 1 1 1 0 UL92 family Shisa PF13908.1 EDN97066.1 - 0.097 12.8 0.9 0.096 12.8 0.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.6 EDN97066.1 - 0.27 10.7 2.2 0.29 10.6 1.5 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Synaptobrevin PF00957.16 EDN97066.1 - 0.73 9.4 6.3 0.92 9.1 4.4 1.2 1 0 0 1 1 1 0 Synaptobrevin HLH PF00010.21 EDN97067.1 - 3.1e-12 45.9 1.2 8e-12 44.6 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Atg14 PF10186.4 EDN97067.1 - 0.015 14.2 3.7 0.03 13.2 2.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EDN97067.1 - 0.027 13.6 4.8 0.048 12.8 3.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Myb_DNA-bind_5 PF13873.1 EDN97067.1 - 0.053 13.4 0.6 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain LtrA PF06772.6 EDN97068.1 - 1.2e-17 63.8 10.9 1.6e-17 63.4 7.6 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Cep57_CLD_2 PF14197.1 EDN97068.1 - 0.11 12.3 3.2 0.3 11.0 1.7 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 KR PF08659.5 EDN97069.1 - 3.5e-60 202.7 1.3 3.5e-60 202.7 0.9 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EDN97069.1 - 5.8e-58 196.7 0.0 9.3e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EDN97069.1 - 1.4e-48 165.0 5.3 4.7e-48 163.2 1.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EDN97069.1 - 5.8e-47 160.2 0.0 9.5e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EDN97069.1 - 8.2e-43 145.0 0.1 4.1e-42 142.7 0.0 2.4 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EDN97069.1 - 6.8e-39 133.8 0.0 1.3e-31 110.0 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N_2 PF13602.1 EDN97069.1 - 7.6e-09 36.5 0.0 2.8e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN97069.1 - 2.3e-07 30.4 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN97069.1 - 0.00012 21.8 0.1 0.0003 20.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EDN97069.1 - 0.00013 22.1 2.8 0.00042 20.5 0.5 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EDN97069.1 - 0.0015 17.9 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EDN97069.1 - 0.014 14.6 0.1 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EDN97069.1 - 0.064 13.3 0.1 0.73 9.9 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 EDN97069.1 - 0.12 12.2 0.1 1.1 9.0 0.1 2.3 2 1 0 3 3 3 0 Alpha/beta hydrolase family Polysacc_synt_2 PF02719.10 EDN97069.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN97069.1 - 0.2 11.6 1.7 4.8 7.1 0.8 3.1 2 1 0 2 2 2 0 NADH(P)-binding FSH1 PF03959.8 EDN97071.1 - 1.7e-30 106.0 0.0 1.6e-29 102.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDN97071.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EDN97071.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ABC_tran PF00005.22 EDN97072.1 - 1.8e-68 229.1 0.0 5.3e-35 120.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN97072.1 - 5.4e-48 163.7 27.4 1.4e-44 152.6 12.4 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN97072.1 - 2.7e-16 59.4 2.0 5.5e-05 22.5 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN97072.1 - 1.4e-14 54.7 0.4 8.1e-05 22.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDN97072.1 - 2.3e-10 39.6 0.3 0.0025 16.4 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EDN97072.1 - 1.6e-08 34.7 0.6 0.00016 21.7 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EDN97072.1 - 3.9e-08 34.1 0.0 0.0026 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDN97072.1 - 4.8e-08 32.3 0.2 0.0068 15.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN97072.1 - 2.3e-07 31.0 2.5 0.033 14.3 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN97072.1 - 2.6e-07 30.0 1.3 0.0004 19.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN97072.1 - 1.5e-06 28.7 0.1 0.014 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDN97072.1 - 4.6e-06 26.4 0.7 0.015 15.1 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EDN97072.1 - 1.2e-05 24.8 0.2 0.19 11.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EDN97072.1 - 7.5e-05 22.3 0.5 0.7 9.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 EDN97072.1 - 0.00012 21.9 0.1 0.31 10.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EDN97072.1 - 0.0002 20.9 0.1 0.054 12.9 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EDN97072.1 - 0.00041 19.8 0.1 0.87 8.9 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EDN97072.1 - 0.00049 20.3 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDN97072.1 - 0.00065 18.8 0.2 0.32 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 EDN97072.1 - 0.00066 19.8 2.9 1.4 9.1 0.0 4.7 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDN97072.1 - 0.00086 19.0 0.0 1 9.1 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EDN97072.1 - 0.0015 18.2 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EDN97072.1 - 0.0076 15.8 0.1 0.88 9.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 EDN97072.1 - 0.0079 15.9 0.0 3 7.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EDN97072.1 - 0.0082 15.2 0.0 0.31 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EDN97072.1 - 0.0091 15.9 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EDN97072.1 - 0.01 14.9 0.3 0.37 9.8 0.0 2.8 3 0 0 3 3 3 0 KaiC ABC_membrane_3 PF13748.1 EDN97072.1 - 0.014 14.4 0.3 0.014 14.4 0.2 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_33 PF13671.1 EDN97072.1 - 0.018 14.9 0.8 4.7 7.0 0.2 2.8 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDN97072.1 - 0.039 13.7 0.6 0.36 10.6 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EDN97072.1 - 0.057 12.2 0.1 9.1 5.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EDN97072.1 - 0.098 12.3 0.9 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase Miro PF08477.8 EDN97072.1 - 0.11 13.0 0.8 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EDN97072.1 - 0.12 11.9 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 EDN97072.1 - 0.13 10.9 0.0 0.49 9.0 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF3590 PF12148.3 EDN97073.1 - 0.01 15.4 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3590) Disulph_isomer PF06491.6 EDN97073.1 - 0.036 13.9 0.3 7.3 6.4 0.0 2.3 1 1 1 2 2 2 0 Disulphide isomerase SH3_1 PF00018.23 EDN97073.1 - 0.11 11.8 0.1 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 SH3 domain Gtr1_RagA PF04670.7 EDN97074.1 - 5.3e-94 313.7 0.1 6.7e-94 313.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EDN97074.1 - 5.6e-07 28.9 0.0 8.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDN97074.1 - 1.4e-06 27.8 0.0 2.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN97074.1 - 9.1e-06 26.1 0.1 2.5e-05 24.7 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN97074.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EDN97074.1 - 0.0027 17.2 0.2 0.0088 15.5 0.2 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain G-alpha PF00503.15 EDN97074.1 - 0.0095 14.6 8.2 0.012 14.3 3.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 EDN97074.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EDN97074.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EDN97074.1 - 0.052 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 EDN97074.1 - 0.064 12.4 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DLIC PF05783.6 EDN97074.1 - 0.078 11.6 0.1 0.17 10.4 0.1 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.4 EDN97074.1 - 0.17 11.3 0.1 0.94 8.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_25 PF01183.15 EDN97075.1 - 0.0032 17.3 0.1 0.0049 16.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Cellulase PF00150.13 EDN97075.1 - 0.096 11.8 2.2 0.18 10.9 1.0 1.8 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) GATase PF00117.23 EDN97076.1 - 3e-06 26.8 0.0 5.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Fungal_trans_2 PF11951.3 EDN97077.1 - 1.7e-06 26.9 0.0 3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2767 PF10965.3 EDN97078.1 - 0.0035 17.1 0.2 6.5 6.6 0.0 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF2767) TraV PF09676.5 EDN97080.1 - 0.41 11.3 3.5 0.67 10.6 2.4 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Lipoprotein_X PF03305.8 EDN97080.1 - 0.96 8.7 5.3 1.2 8.4 3.7 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein MTHFR PF02219.12 EDN97081.1 - 3.5e-102 341.3 0.0 5.2e-102 340.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AIG2 PF06094.7 EDN97083.1 - 1.3e-18 67.3 0.1 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family DUF3859 PF12975.2 EDN97083.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) UPF0029 PF01205.14 EDN97084.1 - 7.9e-31 106.0 0.0 1.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EDN97084.1 - 1.3e-10 41.1 0.0 3.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 RWD domain DDE_1 PF03184.14 EDN97085.1 - 1.5e-27 96.1 0.0 2.5e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN97085.1 - 3.8e-05 23.4 0.1 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3450 PF11932.3 EDN97085.1 - 7.6 5.7 9.2 0.11 11.7 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Chitin_bind_3 PF03067.10 EDN97086.1 - 0.00079 19.7 0.1 0.0024 18.1 0.0 1.8 2 0 0 2 2 2 1 Chitin binding domain Herpes_BLLF1 PF05109.8 EDN97086.1 - 0.19 9.6 37.1 0.29 9.0 25.7 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DDE_1 PF03184.14 EDN97088.1 - 4e-11 42.4 1.7 1.4e-07 30.8 0.3 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease TPR_11 PF13414.1 EDN97089.1 - 7.5e-28 95.9 1.9 3.7e-09 36.0 0.0 3.9 2 1 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 EDN97089.1 - 1.7e-20 71.2 2.1 0.02 14.8 0.0 6.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN97089.1 - 9.9e-20 70.2 4.9 6.1e-09 35.7 0.2 5.0 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDN97089.1 - 7.4e-17 60.1 0.2 0.026 14.1 0.0 6.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97089.1 - 5.9e-15 54.4 6.2 0.0077 16.7 0.1 5.6 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDN97089.1 - 1.6e-12 47.6 2.7 0.00034 21.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDN97089.1 - 5.2e-12 45.2 4.0 0.0052 16.6 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDN97089.1 - 2.4e-09 37.4 2.4 0.0049 17.1 0.1 4.4 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN97089.1 - 1.8e-08 33.5 0.0 0.37 10.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN97089.1 - 2.7e-08 33.3 0.0 0.33 11.2 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN97089.1 - 2.6e-06 26.7 1.1 2.6 8.0 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN97089.1 - 0.001 18.8 1.3 4.7 7.1 0.2 3.6 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDN97089.1 - 0.0055 15.8 0.3 6.2 5.7 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 EDN97089.1 - 0.14 11.3 0.1 9.3 5.2 0.0 2.6 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EDN97089.1 - 0.17 12.4 3.1 21 5.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF572 PF04502.8 EDN97090.1 - 9.1e-75 251.8 12.3 1.1e-74 251.6 8.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EDN97090.1 - 0.026 14.0 0.5 0.048 13.1 0.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EDN97090.1 - 0.036 13.9 0.2 0.13 12.1 0.2 1.8 1 1 0 1 1 1 0 Benyvirus 14KDa protein XAP5 PF04921.9 EDN97090.1 - 0.07 12.6 8.0 0.095 12.2 5.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF4407 PF14362.1 EDN97090.1 - 3.7 6.4 8.5 5.7 5.8 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_4 PF07993.7 EDN97092.1 - 4.6e-34 117.4 0.0 6.9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN97092.1 - 3.9e-26 91.3 0.0 6.2e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EDN97092.1 - 2.3e-07 30.4 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN97092.1 - 1.1e-05 25.6 0.3 2.9e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site DDE_1 PF03184.14 EDN97093.1 - 3.4e-52 176.7 0.0 4.7e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97093.1 - 1.1e-10 40.8 0.7 2.7e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97093.1 - 1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN97093.1 - 0.011 15.6 7.4 0.022 14.6 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc5 PF03221.11 EDN97093.1 - 0.019 14.8 0.5 0.086 12.6 0.0 2.4 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Glyco_hydro_92 PF07971.7 EDN97094.1 - 7.2e-168 559.3 0.1 9e-168 559.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 OPT PF03169.10 EDN97096.1 - 6.1e-166 553.4 60.5 7e-166 553.2 41.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EDN97096.1 - 0.12 11.4 1.8 0.33 9.9 1.3 1.7 1 0 0 1 1 1 0 E1-E2 ATPase COPI_assoc PF08507.5 EDN97096.1 - 2.6 7.7 20.5 0.93 9.1 0.6 3.8 3 0 0 3 3 3 0 COPI associated protein ParA PF10609.4 EDN97097.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ParA/MinD ATPase like Methyltransf_2 PF00891.13 EDN97099.1 - 5.6e-26 91.2 0.0 1.2e-25 90.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EDN97099.1 - 0.00039 20.1 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Herpes_gE PF02480.11 EDN97100.1 - 0.0068 14.7 0.0 0.012 13.9 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EDN97100.1 - 0.025 13.8 1.9 0.025 13.8 1.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Imm33 PF15580.1 EDN97100.1 - 0.026 13.9 0.3 5.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 33 EphA2_TM PF14575.1 EDN97100.1 - 0.032 14.6 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EDN97100.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF3609 PF12259.3 EDN97101.1 - 0.02 13.6 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF3485 PF11984.3 EDN97101.1 - 0.038 13.0 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) CoA_binding_3 PF13727.1 EDN97101.1 - 0.067 13.0 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 CoA-binding domain DUF4010 PF13194.1 EDN97101.1 - 1.7 7.8 5.7 5.8 6.1 3.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) EthD PF07110.6 EDN97102.1 - 0.1 13.5 0.2 1.5 9.7 0.1 2.1 1 1 0 1 1 1 0 EthD domain F-box PF00646.28 EDN97103.1 - 0.017 14.8 0.4 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 F-box domain CENP-B_dimeris PF09026.5 EDN97104.1 - 2.6e-05 24.3 8.6 4.8e-05 23.5 5.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EDN97104.1 - 0.004 16.6 2.3 0.0067 15.9 1.6 1.3 1 0 0 1 1 1 1 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 EDN97104.1 - 0.23 11.1 2.2 0.38 10.4 1.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 EDN97104.1 - 1.5 7.4 9.9 3.4 6.3 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EDN97104.1 - 3 7.0 4.4 4.7 6.3 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EDN97104.1 - 7.2 6.9 11.4 21 5.4 7.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pho88 PF10032.4 EDN97106.1 - 1.9e-79 265.3 0.3 2.2e-79 265.1 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 EDN97107.1 - 3e-28 97.1 2.5 6.4e-28 96.1 1.7 1.6 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 EDN97107.1 - 0.0059 16.3 4.0 0.87 9.4 0.3 2.6 2 0 0 2 2 2 2 YhfH-like protein Staphopain_pro PF14731.1 EDN97107.1 - 0.11 12.2 2.5 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Staphopain proregion Vma12 PF11712.3 EDN97107.1 - 0.6 9.8 4.4 0.31 10.7 0.3 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Fer4_17 PF13534.1 EDN97107.1 - 8.5 6.8 10.2 14 6.0 0.2 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Striatin PF08232.7 EDN97108.1 - 2.2e-40 138.1 2.7 3.6e-40 137.4 1.9 1.4 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 EDN97108.1 - 3.8e-33 112.1 18.7 1.9e-08 33.8 0.1 7.5 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDN97108.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ERM PF00769.14 EDN97108.1 - 0.12 11.8 6.4 0.21 11.1 4.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PIG-P PF08510.7 EDN97109.1 - 0.001 18.7 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 PIG-P Atrophin-1 PF03154.10 EDN97109.1 - 1.4 6.9 5.9 1.4 6.9 4.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_A4 PF01828.12 EDN97110.1 - 5.6e-66 221.5 16.0 6.7e-66 221.3 11.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family ABC2_membrane PF01061.19 EDN97114.1 - 1.4e-92 308.6 61.7 1.4e-47 161.5 15.1 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EDN97114.1 - 4.9e-40 136.9 1.3 8.1e-19 68.2 0.0 3.1 4 0 0 4 4 2 2 ABC transporter PDR_CDR PF06422.7 EDN97114.1 - 2.5e-39 133.0 10.7 6.8e-34 115.6 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EDN97114.1 - 1.3e-17 63.6 0.1 1e-15 57.5 0.0 2.9 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EDN97114.1 - 4.3e-09 36.0 0.0 2.5e-06 27.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EDN97114.1 - 7.8e-06 25.1 0.1 0.0011 18.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EDN97114.1 - 8.2e-06 25.0 14.7 8.2e-06 25.0 10.2 3.9 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.1 EDN97114.1 - 6.2e-05 22.4 0.9 0.037 13.5 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDN97114.1 - 0.00011 22.0 0.0 0.016 15.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDN97114.1 - 0.00018 21.5 0.9 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EDN97114.1 - 0.0007 19.0 1.1 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EDN97114.1 - 0.0014 18.9 0.1 0.061 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDN97114.1 - 0.0025 17.8 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDN97114.1 - 0.003 18.3 0.0 0.13 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN97114.1 - 0.0041 17.2 0.2 0.76 9.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDN97114.1 - 0.016 14.7 0.2 0.32 10.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EDN97114.1 - 0.018 14.7 0.4 3.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain MMR_HSR1 PF01926.18 EDN97114.1 - 0.019 14.9 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 EDN97114.1 - 0.024 13.8 0.1 0.55 9.4 0.0 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EDN97114.1 - 0.026 14.2 0.8 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EDN97114.1 - 0.042 14.0 0.1 4.6 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 EDN97114.1 - 0.051 13.2 1.6 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4523 PF15023.1 EDN97114.1 - 0.068 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Miro PF08477.8 EDN97114.1 - 0.08 13.4 0.1 13 6.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DDE_1 PF03184.14 EDN97116.1 - 1.7e-09 37.1 0.2 2.7e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97116.1 - 1.9e-09 36.9 0.0 3.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN97116.1 - 3.8e-09 36.2 0.4 8.5e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.15 EDN97116.1 - 0.01 15.7 0.6 0.1 12.5 0.1 2.6 3 0 0 3 3 3 0 Transposase NUMOD1 PF07453.8 EDN97116.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain HTH_Tnp_Tc5 PF03221.11 EDN97117.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3928 PF13065.1 EDN97117.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3928) Sipho_tail PF05709.6 EDN97119.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein MFS_1 PF07690.11 EDN97120.1 - 3.5e-42 144.3 38.6 1.1e-41 142.7 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN97120.1 - 2.6e-11 42.7 8.7 2.6e-11 42.7 6.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EDN97120.1 - 1.8e-06 26.4 3.7 1.8e-06 26.4 2.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EDN97121.1 - 1.4e-37 129.3 0.0 3.5e-37 128.0 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Histone PF00125.19 EDN97124.1 - 4.3e-22 78.0 0.0 5.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN97124.1 - 4.1e-05 23.5 0.3 7.4e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zn_clus PF00172.13 EDN97126.1 - 0.0004 20.2 14.3 0.0004 20.2 9.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN97126.1 - 0.033 12.7 2.6 1.1 7.8 0.1 2.9 3 0 0 3 3 3 0 Fungal specific transcription factor domain HSF_DNA-bind PF00447.12 EDN97127.1 - 6.5e-28 96.9 0.1 1.5e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.16 EDN97128.1 - 4.8e-39 134.0 0.0 9.4e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GET2 PF08690.5 EDN97128.1 - 5.7 6.0 5.4 10 5.2 3.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 R3H PF01424.17 EDN97129.1 - 5e-11 42.1 0.0 1.1e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EDN97129.1 - 6.4e-10 38.8 0.6 3.2e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN97129.1 - 1.3e-07 31.1 0.0 3.2e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN97129.1 - 0.00094 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DS PF01916.12 EDN97137.1 - 4.8e-142 472.4 0.0 5.7e-142 472.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EDN97137.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EDN97138.1 - 3.1e-05 23.9 0.2 0.32 11.0 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain CLU PF13236.1 EDN97139.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Clustered mitochondria TIL PF01826.12 EDN97140.1 - 1.9 8.6 7.0 0.41 10.8 2.6 1.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain LSM14 PF12701.2 EDN97142.1 - 4.9e-27 93.5 0.0 8.9e-27 92.7 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EDN97142.1 - 4.2e-22 78.6 4.2 4.2e-22 78.6 2.9 2.2 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EDN97142.1 - 0.0015 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 EDN97142.1 - 5.8 7.4 34.4 0.22 12.0 19.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family UPF0061 PF02696.9 EDN97143.1 - 2.1e-116 389.1 0.0 2.6e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.16 EDN97144.1 - 7e-38 130.0 0.0 8.2e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_H PF00075.19 EDN97145.1 - 0.00041 20.7 0.0 0.00066 20.0 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN97145.1 - 0.019 14.7 0.0 0.72 9.6 0.0 2.9 3 0 0 3 3 3 0 Reverse transcriptase-like XRCC4 PF06632.7 EDN97146.1 - 0.0063 15.4 18.7 0.013 14.3 13.0 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1980 PF09323.5 EDN97146.1 - 1.3 8.7 10.4 0.59 9.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PRK PF00485.13 EDN97150.1 - 0.056 13.0 0.2 0.066 12.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF1993 PF09351.5 EDN97150.1 - 0.11 12.3 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) RNase_H PF00075.19 EDN97151.1 - 7.8e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN97151.1 - 9e-05 22.1 0.0 0.00072 19.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase-like PYRIN PF02758.11 EDN97152.1 - 0.09 12.4 0.1 8.2 6.2 0.1 2.6 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain BTB PF00651.26 EDN97153.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF2890 PF11081.3 EDN97154.1 - 0.76 9.8 3.1 1.2 9.1 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EDN97154.1 - 2.1 6.1 6.9 2.4 5.9 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pneumo_att_G PF05539.6 EDN97155.1 - 0.023 14.0 4.2 0.027 13.8 2.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RR_TM4-6 PF06459.7 EDN97155.1 - 0.21 11.4 5.6 0.22 11.3 3.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.8 EDN97156.1 - 0.029 13.4 6.6 0.035 13.2 4.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 EDN97156.1 - 0.13 11.7 7.1 0.18 11.2 4.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SR-25 PF10500.4 EDN97157.1 - 0.0039 16.7 11.3 0.0057 16.1 7.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 EDN97157.1 - 0.25 9.9 2.4 0.32 9.6 1.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.12 EDN97157.1 - 0.96 8.2 2.5 1.2 7.8 1.7 1.1 1 0 0 1 1 1 0 Presenilin DUF3251 PF11622.3 EDN97158.1 - 0.27 10.6 2.3 3.3 7.0 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3251) Cpn60_TCP1 PF00118.19 EDN97159.1 - 2.1e-116 389.4 9.5 2.4e-116 389.2 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 EDN97159.1 - 0.046 13.8 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator DDE_1 PF03184.14 EDN97160.1 - 2.8e-26 91.9 0.9 1.8e-23 82.8 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97160.1 - 2.2e-07 30.6 0.1 1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN97160.1 - 0.012 15.5 6.7 0.028 14.3 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EDN97161.1 - 0.016 14.3 3.4 0.074 12.1 0.3 2.0 1 1 1 2 2 2 0 DDE superfamily endonuclease Cofilin_ADF PF00241.15 EDN97162.1 - 3.3e-28 98.0 0.5 4.1e-28 97.8 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.2 EDN97163.1 - 1.9e-36 126.2 1.2 3.6e-30 105.6 0.2 2.4 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 EDN97163.1 - 7.8e-08 31.6 0.0 1.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN97163.1 - 0.0004 20.0 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Nol1_Nop2_Fmu PF01189.12 EDN97164.1 - 6.7e-99 330.8 0.0 4.8e-98 328.0 0.0 2.2 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EDN97164.1 - 0.00036 20.1 0.0 0.00092 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDN97164.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Chromo PF00385.19 EDN97167.1 - 3.8e-07 29.6 0.2 0.00016 21.3 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH PF00642.19 EDN97167.1 - 0.52 10.0 21.4 0.53 10.0 0.7 4.2 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HTH_psq PF05225.11 EDN97168.1 - 4.5e-12 45.3 0.2 7e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_3 PF01381.17 EDN97168.1 - 0.0002 21.1 0.1 0.00035 20.3 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.1 EDN97168.1 - 0.0021 17.6 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc5 PF03221.11 EDN97168.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EDN97168.1 - 0.01 15.7 0.5 0.02 14.7 0.2 1.6 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_28 PF13518.1 EDN97168.1 - 0.041 13.8 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 EDN97168.1 - 0.079 12.6 0.1 0.085 12.5 0.1 1.2 1 0 0 1 1 1 0 Transposase HTH_37 PF13744.1 EDN97168.1 - 0.082 12.7 0.8 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SieB PF14163.1 EDN97168.1 - 0.09 12.3 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B Ras PF00071.17 EDN97169.1 - 1.6e-63 212.9 0.2 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN97169.1 - 6.1e-22 78.3 0.1 8.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN97169.1 - 2.5e-13 49.6 0.1 3.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDN97169.1 - 3.3e-08 33.4 0.1 5.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN97169.1 - 3.8e-05 23.2 0.1 0.00013 21.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN97169.1 - 6e-05 22.2 0.1 9.8e-05 21.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EDN97169.1 - 0.0001 22.4 0.2 0.00031 20.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDN97169.1 - 0.001 18.9 0.1 0.0029 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EDN97169.1 - 0.0019 17.3 0.0 0.0024 16.9 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EDN97169.1 - 0.0028 16.8 0.1 0.0066 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EDN97169.1 - 0.0069 16.2 0.1 0.085 12.8 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EDN97169.1 - 0.0094 15.1 0.0 0.018 14.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EDN97169.1 - 0.021 14.7 0.4 0.049 13.6 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EDN97169.1 - 0.022 15.0 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EDN97169.1 - 0.023 14.3 0.2 0.058 12.9 0.0 1.6 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 EDN97169.1 - 0.083 12.1 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EDN97169.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDN97169.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Brix PF04427.13 EDN97171.1 - 4.5e-39 134.0 0.1 5.8e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain Reo_sigmaC PF04582.7 EDN97172.1 - 0.00035 19.8 42.8 0.028 13.6 3.2 6.3 1 1 6 7 7 7 4 Reovirus sigma C capsid protein DUF4201 PF13870.1 EDN97172.1 - 0.054 12.9 0.2 0.054 12.9 0.1 6.0 5 2 1 6 6 6 0 Domain of unknown function (DUF4201) DASH_Dad3 PF08656.5 EDN97172.1 - 0.14 11.8 0.1 0.14 11.8 0.1 7.1 3 3 3 7 7 7 0 DASH complex subunit Dad3 Spectrin PF00435.16 EDN97172.1 - 0.16 12.2 46.6 0.048 13.9 2.2 7.1 6 3 1 7 7 7 0 Spectrin repeat DUF1664 PF07889.7 EDN97172.1 - 0.38 10.5 40.5 0.79 9.5 0.1 7.3 6 1 0 7 7 7 0 Protein of unknown function (DUF1664) Tape_meas_lam_C PF09718.5 EDN97172.1 - 0.41 10.5 3.5 3.9 7.4 0.0 4.1 6 0 0 6 6 6 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) IncA PF04156.9 EDN97172.1 - 0.5 9.9 57.1 0.15 11.6 0.5 6.9 3 1 2 5 5 5 0 IncA protein AAA_13 PF13166.1 EDN97172.1 - 0.88 7.9 55.7 0.051 12.0 1.0 3.9 1 1 2 4 4 4 0 AAA domain DUF3584 PF12128.3 EDN97172.1 - 1.1 6.4 55.1 0.26 8.5 20.0 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Surfac_D-trimer PF09006.6 EDN97172.1 - 1.4 8.6 8.4 14 5.5 0.0 5.2 6 0 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation Filament PF00038.16 EDN97172.1 - 4.1 6.7 53.4 0.19 11.1 2.7 5.4 1 1 3 5 5 5 0 Intermediate filament protein DUF1515 PF07439.6 EDN97172.1 - 4.2 7.2 23.6 0.23 11.2 0.3 5.8 5 1 2 7 7 6 0 Protein of unknown function (DUF1515) Tropomyosin_1 PF12718.2 EDN97172.1 - 5.1 6.9 66.4 0.11 12.3 1.1 7.3 4 3 3 8 8 8 0 Tropomyosin like Fib_alpha PF08702.5 EDN97172.1 - 6.7 6.8 50.9 1.2 9.3 2.7 6.7 2 2 6 8 8 8 0 Fibrinogen alpha/beta chain family DUF2937 PF11157.3 EDN97172.1 - 7.9 5.7 9.2 9 5.5 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) TIP49 PF06068.8 EDN97174.1 - 1.3e-176 587.2 3.7 1.5e-176 586.9 2.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDN97174.1 - 5.3e-09 35.4 1.8 3.9e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EDN97174.1 - 2.2e-08 34.3 1.2 4.6e-05 23.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EDN97174.1 - 9.2e-07 27.9 0.7 1.6e-06 27.2 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EDN97174.1 - 6.7e-05 22.9 0.0 0.0049 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN97174.1 - 0.00034 20.7 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDN97174.1 - 0.00071 19.4 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EDN97174.1 - 0.0012 18.0 1.0 0.027 13.6 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EDN97174.1 - 0.0028 17.0 0.1 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN97174.1 - 0.0034 17.1 0.0 0.6 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDN97174.1 - 0.0062 16.0 0.1 3.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EDN97174.1 - 0.015 15.0 0.7 0.078 12.7 0.2 2.3 2 1 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDN97174.1 - 0.045 13.2 0.4 0.41 10.1 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.1 EDN97174.1 - 0.058 12.9 0.3 0.1 12.1 0.2 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EDN97174.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EDN97174.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 EDN97175.1 - 2.9e-12 45.9 0.7 5.3e-12 45.1 0.5 1.5 1 0 0 1 1 1 1 GYF domain DUF2464 PF10240.4 EDN97176.1 - 0.14 11.4 0.6 0.17 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) RNA_pol_Rpb2_3 PF04565.11 EDN97176.1 - 0.62 9.8 8.0 73 3.2 5.6 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 3 GcrA PF07750.6 EDN97176.1 - 1.1 9.4 4.7 1.2 9.3 3.3 1.0 1 0 0 1 1 1 0 GcrA cell cycle regulator Nab6_mRNP_bdg PF10567.4 EDN97176.1 - 1.9 7.4 6.4 2 7.3 4.4 1.0 1 0 0 1 1 1 0 RNA-recognition motif Orexin_rec2 PF03827.8 EDN97176.1 - 8.7 6.4 8.2 1.8e+02 2.2 5.7 2.2 1 1 0 1 1 1 0 Orexin receptor type 2 UFD1 PF03152.9 EDN97177.1 - 3.4e-58 195.6 0.0 4.6e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 HTH_23 PF13384.1 EDN97178.1 - 0.029 14.0 0.3 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain WGR PF05406.10 EDN97178.1 - 0.51 10.3 3.3 0.33 10.9 0.2 2.0 2 0 0 2 2 2 0 WGR domain DUF1849 PF08904.6 EDN97179.1 - 0.08 12.2 1.0 0.83 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1849) DUF1180 PF06679.7 EDN97180.1 - 0.035 13.9 0.2 0.038 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DTHCT PF08070.6 EDN97180.1 - 0.039 14.5 5.2 0.048 14.3 3.6 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region IER PF05760.7 EDN97180.1 - 0.041 13.8 1.6 0.046 13.6 1.1 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Ribosomal_60s PF00428.14 EDN97180.1 - 0.047 14.0 0.4 0.076 13.4 0.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein hNIFK_binding PF12196.3 EDN97180.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK YolD PF08863.5 EDN97183.1 - 0.062 13.1 0.5 0.093 12.5 0.3 1.3 1 0 0 1 1 1 0 YolD-like protein CorA PF01544.13 EDN97187.1 - 5.1e-11 42.1 0.8 5.1e-11 42.1 0.5 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ABC2_membrane PF01061.19 EDN97187.1 - 0.049 12.7 11.6 0.076 12.1 8.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Memo PF01875.12 EDN97188.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Memo-like protein PP28 PF10252.4 EDN97191.1 - 1.9e-25 88.6 19.0 1.9e-25 88.6 13.2 3.5 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EDN97191.1 - 0.65 8.4 30.9 0.75 8.2 21.4 1.1 1 0 0 1 1 1 0 Daxx Family Angiomotin_C PF12240.3 EDN97192.1 - 0.046 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Angiomotin C terminal Lgl_C PF08596.5 EDN97193.1 - 3e-120 401.3 0.0 6.2e-120 400.2 0.0 1.5 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EDN97193.1 - 8.6e-06 25.4 1.5 0.05 13.4 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN97193.1 - 0.065 11.9 0.0 0.26 10.0 0.0 2.0 3 0 0 3 3 3 0 Nup133 N terminal like ASF1_hist_chap PF04729.8 EDN97195.1 - 4.7e-66 221.1 0.0 6.3e-66 220.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.9 EDN97196.1 - 4.5e-85 285.7 0.1 4.5e-85 285.7 0.1 4.3 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EDN97196.1 - 2.7e-06 27.8 0.2 1.4e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97196.1 - 6.4e-06 26.3 0.1 0.0012 19.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN97196.1 - 0.0016 18.7 0.0 0.03 14.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.11 EDN97196.1 - 0.0017 18.0 0.1 0.55 10.0 0.0 2.7 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_7 PF13176.1 EDN97196.1 - 0.086 12.6 0.1 13 5.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Piwi PF02171.12 EDN97198.1 - 2.6e-77 259.7 0.1 4.8e-77 258.8 0.1 1.4 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EDN97198.1 - 3.8e-20 70.9 0.1 8e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EDN97198.1 - 5.1e-13 48.5 1.2 1.1e-12 47.4 0.8 1.5 1 0 0 1 1 1 1 PAZ domain Ras PF00071.17 EDN97200.1 - 1.2e-38 132.0 0.0 8.7e-25 86.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN97200.1 - 3.1e-13 50.2 0.0 6.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN97200.1 - 3e-05 23.9 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EDN97200.1 - 0.00076 18.7 0.1 0.0073 15.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN97200.1 - 0.025 14.0 0.1 1.1 8.6 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 EDN97200.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AMMECR1 PF01871.12 EDN97202.1 - 1.5e-41 141.4 0.0 4.4e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 2-Hacid_dh_C PF02826.14 EDN97204.1 - 2.8e-35 121.0 0.0 3.9e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN97204.1 - 3e-20 72.0 0.0 3.8e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Oxidored_q2 PF00420.19 EDN97206.1 - 0.048 13.2 0.1 0.058 12.9 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Wzz PF02706.10 EDN97206.1 - 0.07 12.9 0.1 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Chain length determinant protein FtsL PF04999.8 EDN97206.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsL GTP_EFTU PF00009.22 EDN97209.1 - 4e-40 137.2 2.3 1.9e-39 135.0 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDN97209.1 - 6.3e-25 87.1 0.4 1.5e-24 85.9 0.3 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDN97209.1 - 2.9e-11 43.3 1.5 7.2e-06 26.0 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EDN97209.1 - 9.6e-09 34.7 0.1 2.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EDN97209.1 - 3.6e-08 33.3 0.1 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN97209.1 - 8.3e-07 29.5 0.1 2.4e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN97209.1 - 5.2e-05 22.5 0.0 9.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EDN97209.1 - 0.00024 20.5 0.2 0.00067 19.1 0.2 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EDN97209.1 - 0.00059 19.0 0.0 0.0018 17.5 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EDN97209.1 - 0.0072 15.6 0.1 0.024 13.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 EDN97209.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Ras family Pyridoxal_deC PF00282.14 EDN97210.1 - 5.5e-79 265.3 0.0 2.8e-78 262.9 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EDN97210.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDN97210.1 - 0.00028 19.7 0.0 0.00039 19.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.14 EDN97211.1 - 1.8e-08 33.3 0.2 3.4 7.3 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Arg_repressor_C PF02863.13 EDN97212.1 - 0.11 12.0 0.1 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF367 PF04034.8 EDN97213.1 - 1e-47 160.9 0.1 1.4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EDN97213.1 - 5.4e-12 45.0 1.0 1.2e-11 43.9 0.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.14 EDN97214.1 - 9.9e-48 161.3 0.0 3.5e-47 159.5 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EDN97214.1 - 4.3e-25 87.6 0.7 1.2e-24 86.2 0.5 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EDN97214.1 - 6.4e-15 55.4 0.7 6.4e-15 55.4 0.5 2.1 3 0 0 3 3 3 1 Adaptin C-terminal domain SET PF00856.23 EDN97215.1 - 0.58 10.4 10.7 0.68 10.2 7.4 1.1 1 0 0 1 1 1 0 SET domain DUF2201_N PF13203.1 EDN97215.1 - 0.9 8.6 18.2 1 8.5 12.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 EDN97215.1 - 1 9.3 44.4 1.2 9.0 30.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.8 EDN97215.1 - 1.4 8.4 42.1 1.8 8.0 29.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF1510 PF07423.6 EDN97215.1 - 1.4 8.1 39.2 1.6 8.0 27.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Corona_nucleoca PF00937.13 EDN97215.1 - 1.9 7.3 32.9 2.2 7.1 22.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DDHD PF02862.12 EDN97215.1 - 4.2 7.1 25.0 5.3 6.7 17.4 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EDN97215.1 - 4.6 7.0 31.5 5.6 6.7 21.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EDN97215.1 - 4.9 5.0 25.2 5.5 4.9 17.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 EDN97215.1 - 5.3 6.2 30.1 5.9 6.1 20.9 1.0 1 0 0 1 1 1 0 SprA-related family DUF2992 PF11208.3 EDN97215.1 - 8.6 6.2 48.4 12 5.8 33.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) NB-ARC PF00931.17 EDN97216.1 - 1.6e-08 33.7 0.0 2.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EDN97216.1 - 2.8e-08 33.9 0.2 1.3e-06 28.5 0.2 3.0 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 EDN97216.1 - 2.9e-05 23.4 0.1 6.9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 EDN97216.1 - 0.00077 19.6 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN97216.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Abhydrolase_6 PF12697.2 EDN97216.1 - 0.013 15.4 0.0 0.047 13.5 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_14 PF13173.1 EDN97216.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.8 EDN97216.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FHA PF00498.21 EDN97219.1 - 1e-15 57.5 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 EDN97224.1 - 3.4e-15 55.6 26.5 3.4e-15 55.6 18.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN97224.1 - 3.1 6.2 23.8 8.1 4.8 13.8 2.7 1 1 0 2 2 2 0 Sugar (and other) transporter DUF221 PF02714.10 EDN97227.1 - 7.4e-106 353.6 21.0 1.4e-105 352.7 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN97227.1 - 8.5e-42 142.3 1.1 8.5e-42 142.3 0.8 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDN97227.1 - 3e-27 94.3 0.0 5e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN97227.1 - 2.4e-12 47.1 0.0 3.6e-11 43.4 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) Colicin_V PF02674.11 EDN97227.1 - 0.0018 18.1 4.0 0.0018 18.1 2.7 2.5 2 1 0 2 2 2 1 Colicin V production protein RRM_5 PF13893.1 EDN97227.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2456 PF10445.4 EDN97227.1 - 0.66 9.9 7.4 0.2 11.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Aldo_ket_red PF00248.16 EDN97228.1 - 1e-49 168.8 0.0 1.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EDN97229.1 - 9.5e-23 80.4 34.3 1e-22 80.3 22.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 EDN97229.1 - 0.02 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2407_C PF13373.1 EDN97229.1 - 5 7.0 6.0 5.4 6.9 0.7 3.1 3 0 0 3 3 3 0 DUF2407 C-terminal domain FAD_binding_4 PF01565.18 EDN97230.1 - 4.4e-15 55.3 0.0 7.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lipase3_N PF03893.11 EDN97230.1 - 0.049 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Lipase 3 N-terminal region Dicty_CAR PF05462.6 EDN97231.1 - 1.5e-12 47.0 10.6 1.5e-12 47.0 7.4 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 EDN97231.1 - 2.7e-06 27.0 12.6 2.7e-06 27.0 8.8 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Sarcoglycan_2 PF05510.8 EDN97231.1 - 0.011 14.0 0.0 0.019 13.3 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon CcmH PF03918.9 EDN97231.1 - 0.98 8.4 3.2 3.1 6.7 0.2 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein COX2-transmemb PF09125.5 EDN97231.1 - 2.5 7.7 5.4 2.8 7.5 0.2 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane BTB PF00651.26 EDN97232.1 - 3.8e-06 26.8 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ceramidase PF05875.7 EDN97234.1 - 1.3e-56 191.6 5.9 1.5e-56 191.4 4.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF788 PF05620.6 EDN97234.1 - 0.14 12.0 2.6 1.6 8.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF788) InaF-motif PF15018.1 EDN97234.1 - 0.15 11.5 4.5 0.17 11.3 0.3 2.5 2 0 0 2 2 2 0 TRP-interacting helix DUF4401 PF14351.1 EDN97234.1 - 0.26 10.2 5.0 0.38 9.6 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) RNase_H PF00075.19 EDN97235.1 - 1.6e-13 51.1 0.0 3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.11 EDN97236.1 - 4.4e-16 58.5 25.1 8e-16 57.6 15.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 EDN97238.1 - 1.7e-107 358.7 0.0 2.3e-107 358.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EDN97238.1 - 1.7e-41 141.5 0.4 3.5e-41 140.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.1 EDN97238.1 - 0.0016 18.6 1.0 0.0049 17.1 0.7 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain HsbA PF12296.3 EDN97239.1 - 0.00041 20.1 0.2 0.00071 19.4 0.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A VirD1 PF07328.6 EDN97239.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Glyco_hydro_71 PF03659.9 EDN97240.1 - 1.8e-132 441.5 4.9 2.1e-132 441.2 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 RVT_1 PF00078.22 EDN97241.1 - 1.4e-35 122.5 0.6 3.1e-35 121.4 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN97241.1 - 2.4e-21 75.5 3.1 2.6e-21 75.4 1.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN97241.1 - 1.3e-14 54.6 0.0 3.2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN97241.1 - 9.2e-05 22.4 0.7 0.00016 21.6 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EDN97241.1 - 0.011 16.0 0.1 0.045 14.0 0.0 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase p450 PF00067.17 EDN97243.1 - 1.7e-54 185.1 0.0 2.1e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3328 PF11807.3 EDN97245.1 - 2.1e-15 57.0 0.1 2.4e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EDN97246.1 - 1.4e-17 64.1 6.3 3.6e-17 62.7 1.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Peptidase_M50 PF02163.17 EDN97248.1 - 0.096 11.6 0.2 0.28 10.1 0.0 1.9 1 1 1 2 2 2 0 Peptidase family M50 APH PF01636.18 EDN97249.1 - 2.7e-15 56.7 0.0 4.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN97249.1 - 3.4e-05 23.2 0.2 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 RIO1 family EcKinase PF02958.15 EDN97249.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN97249.1 - 0.0087 15.6 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3530 PF12048.3 EDN97250.1 - 0.16 10.9 1.9 0.24 10.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3047 PF11249.3 EDN97254.1 - 0.04 13.2 0.7 0.04 13.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) AA_permease_2 PF13520.1 EDN97255.1 - 1.1e-55 188.8 53.7 1.4e-55 188.5 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN97255.1 - 3.8e-14 51.8 47.2 6e-14 51.2 32.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 EDN97255.1 - 0.00041 20.0 10.7 0.0015 18.2 0.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4234) AA_permease PF00324.16 EDN97256.1 - 1.2e-130 436.0 45.2 1.4e-130 435.8 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN97256.1 - 3.8e-32 111.3 50.9 4.8e-32 111.0 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 EDN97259.1 - 3.7e-19 68.9 0.1 3.5e-09 36.1 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EDN97259.1 - 0.0011 18.8 0.2 0.0028 17.6 0.1 1.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN97259.1 - 0.0031 17.8 0.2 0.016 15.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN97259.1 - 0.0056 15.6 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN97259.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDN97259.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EDN97259.1 - 0.042 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EDN97259.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EDN97259.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EDN97259.1 - 0.093 12.7 0.3 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain ACP_syn_III PF08545.5 EDN97259.1 - 0.12 12.0 0.4 0.36 10.5 0.0 2.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 EDN97261.1 - 0.038 13.5 0.1 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EDN97261.1 - 0.11 11.9 0.1 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.21 EDN97264.1 - 5.4e-72 242.3 0.0 1.4e-71 240.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDN97264.1 - 1.4e-53 182.3 0.0 2.6e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 EDN97264.1 - 5.9e-37 128.0 0.0 1.5e-36 126.7 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EDN97264.1 - 9.8e-37 125.4 1.2 2.4e-36 124.2 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EDN97264.1 - 8.1e-19 67.6 4.5 4.3e-10 39.7 0.3 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EDN97264.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EDN97264.1 - 1.8e-07 31.2 0.4 0.0026 17.6 0.0 3.7 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN97264.1 - 3e-07 30.2 0.0 0.12 12.1 0.0 4.0 4 0 0 4 4 4 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EDN97264.1 - 0.00028 19.9 0.0 0.00098 18.1 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EDN97264.1 - 0.097 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ABC_tran PF00005.22 EDN97272.1 - 8.5e-47 158.8 0.0 1.5e-22 80.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EDN97272.1 - 1.5e-38 132.0 38.2 2e-25 89.1 9.6 3.4 3 1 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 EDN97272.1 - 2.2e-17 63.9 6.1 6.6e-05 23.0 0.0 4.5 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN97272.1 - 1.1e-07 31.3 0.4 0.0018 17.5 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN97272.1 - 4.5e-07 29.2 4.2 0.0062 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN97272.1 - 5.5e-07 30.1 2.8 0.0005 20.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDN97272.1 - 9.3e-07 28.4 1.1 0.033 13.5 0.3 2.9 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 EDN97272.1 - 1.7e-06 28.2 0.1 0.018 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDN97272.1 - 2e-06 27.8 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EDN97272.1 - 2.6e-06 26.7 1.7 0.0056 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EDN97272.1 - 1.4e-05 24.3 0.1 1.2 8.0 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 EDN97272.1 - 2.1e-05 24.3 1.2 0.54 10.2 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EDN97272.1 - 3.1e-05 24.7 0.1 0.45 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDN97272.1 - 4.1e-05 23.2 1.3 0.29 10.7 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.1 EDN97272.1 - 5.5e-05 23.1 2.7 0.17 11.8 0.9 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EDN97272.1 - 0.00019 20.9 2.9 0.066 12.6 0.5 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.17 EDN97272.1 - 0.0002 21.5 0.2 0.66 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.1 EDN97272.1 - 0.00028 20.5 0.6 0.52 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF4388 PF14332.1 EDN97272.1 - 0.00034 20.4 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF4388) AAA_10 PF12846.2 EDN97272.1 - 0.00037 20.0 5.5 0.15 11.4 0.8 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 EDN97272.1 - 0.00052 19.7 1.1 0.43 10.3 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EDN97272.1 - 0.00061 20.1 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EDN97272.1 - 0.00077 18.4 2.1 0.35 9.7 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.14 EDN97272.1 - 0.00082 18.8 3.4 0.29 10.5 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EDN97272.1 - 0.00096 18.9 0.2 0.084 12.5 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 EDN97272.1 - 0.0012 19.3 0.5 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 EDN97272.1 - 0.003 17.1 0.7 0.9 9.0 0.2 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EDN97272.1 - 0.0046 16.6 1.0 3.3 7.3 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EDN97272.1 - 0.0049 16.4 0.9 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN97272.1 - 0.005 16.7 0.3 2.5 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EDN97272.1 - 0.0054 16.6 3.1 0.85 9.6 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 EDN97272.1 - 0.011 15.4 3.3 0.76 9.4 0.6 3.4 4 0 0 4 4 4 0 NTPase Pox_A32 PF04665.7 EDN97272.1 - 0.018 14.3 1.2 0.61 9.3 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 EDN97272.1 - 0.021 14.3 0.8 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EDN97272.1 - 0.021 14.9 0.4 6.1 7.0 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EDN97272.1 - 0.022 14.5 0.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 EDN97272.1 - 0.026 14.2 1.5 7.2 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EDN97272.1 - 0.038 13.0 1.4 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EDN97272.1 - 0.054 13.3 1.4 11 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EDN97272.1 - 0.13 11.2 1.5 2.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Septin PRK PF00485.13 EDN97272.1 - 0.15 11.6 1.6 5.3 6.5 0.3 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 EDN97272.1 - 0.28 10.8 1.6 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EDN97272.1 - 0.38 9.9 1.5 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ABC_ATPase PF09818.4 EDN97272.1 - 0.43 9.1 1.8 6.7 5.1 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.12 EDN97272.1 - 0.67 9.3 4.1 2.4 7.5 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein SRP54 PF00448.17 EDN97272.1 - 0.93 8.8 3.6 15 4.9 0.7 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EDN97272.1 - 5.1 5.6 4.7 4.4 5.8 0.9 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MutS_V PF00488.16 EDN97273.1 - 1.3e-78 263.6 0.2 3.9e-69 232.6 0.1 2.2 1 1 1 2 2 2 2 MutS domain V MutS_IV PF05190.13 EDN97273.1 - 3.6e-12 46.2 0.3 9.9e-12 44.8 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.13 EDN97273.1 - 0.0019 18.0 0.1 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain III NTPase_1 PF03266.10 EDN97273.1 - 0.076 12.7 0.4 8.3 6.0 0.0 2.6 3 0 0 3 3 3 0 NTPase DUF1268 PF06896.6 EDN97273.1 - 0.23 11.8 1.5 9.3 6.6 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1268) tRNA_m1G_MT PF01746.16 EDN97274.1 - 1.6e-25 89.7 0.0 2.6e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Zn_clus PF00172.13 EDN97276.1 - 1.3e-07 31.4 8.7 1.3e-07 31.4 6.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN97276.1 - 2.1e-06 26.6 0.0 3e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA PF00004.24 EDN97278.1 - 2.4e-45 153.9 0.7 5.5e-45 152.7 0.0 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN97278.1 - 3.3e-09 36.5 0.3 1.2e-08 34.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN97278.1 - 4.2e-08 33.2 0.0 8.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN97278.1 - 5e-07 29.8 0.0 1.6e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN97278.1 - 8.7e-07 29.1 0.6 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EDN97278.1 - 3.8e-06 26.0 0.0 7.5e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EDN97278.1 - 0.00013 21.8 0.0 0.00059 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN97278.1 - 0.00034 21.4 0.0 0.0019 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN97278.1 - 0.00035 19.7 0.0 0.00081 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDN97278.1 - 0.00043 20.2 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN97278.1 - 0.001 18.7 0.4 0.057 13.0 0.0 2.9 3 1 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.7 EDN97278.1 - 0.001 18.1 0.1 0.0037 16.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EDN97278.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EDN97278.1 - 0.0015 18.2 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EDN97278.1 - 0.0015 17.3 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EDN97278.1 - 0.0031 17.2 0.0 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_3 PF07726.6 EDN97278.1 - 0.004 16.7 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EDN97278.1 - 0.0046 16.5 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EDN97278.1 - 0.0048 17.2 0.3 0.81 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDN97278.1 - 0.0051 16.4 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN97278.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN97278.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDN97278.1 - 0.0065 16.1 0.6 0.06 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EDN97278.1 - 0.0073 15.7 0.8 0.078 12.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 EDN97278.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN97278.1 - 0.011 15.2 0.3 0.024 14.0 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EDN97278.1 - 0.014 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EDN97278.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EDN97278.1 - 0.025 13.6 0.9 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EDN97278.1 - 0.028 14.7 0.0 0.096 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EDN97278.1 - 0.046 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EDN97278.1 - 0.056 13.4 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EDN97278.1 - 0.075 11.3 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 EDN97278.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EDN97278.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2410 PF10307.4 EDN97284.1 - 1.3e-82 275.9 0.0 1.8e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF167 PF02594.11 EDN97285.1 - 7.4e-13 48.2 0.0 9.8e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Response_reg PF00072.19 EDN97287.1 - 4.3e-21 75.0 0.2 6.6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 EDN97287.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1722 PF08349.6 EDN97287.1 - 0.014 15.2 0.8 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) W2 PF02020.13 EDN97288.1 - 1e-19 70.2 1.3 1e-19 70.2 0.9 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EDN97288.1 - 1.4e-09 36.9 9.3 0.06 12.8 0.1 4.5 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EDN97288.1 - 1.4e-06 27.8 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EDN97288.1 - 0.00027 20.4 7.9 0.049 13.2 0.8 3.4 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EDN97288.1 - 0.00034 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Bcl-2_BAD PF10514.4 EDN97288.1 - 0.017 15.0 0.9 0.017 15.0 0.6 2.1 2 1 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD DUF4171 PF13775.1 EDN97288.1 - 0.022 14.9 0.9 0.022 14.9 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) Clp1 PF06807.9 EDN97289.1 - 2.5e-11 43.7 0.0 1.1e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EDN97289.1 - 0.0014 18.3 0.0 0.014 15.1 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDN97289.1 - 0.0047 17.7 0.1 0.027 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN97289.1 - 0.0068 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN97289.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sporozoite_P67 PF05642.6 EDN97289.1 - 0.041 11.7 5.3 0.069 11.0 3.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EDN97289.1 - 0.17 9.7 11.2 0.26 9.1 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 EDN97289.1 - 0.19 11.4 3.9 0.59 9.8 2.7 1.8 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PI3K_1B_p101 PF10486.4 EDN97289.1 - 0.19 9.2 2.9 0.28 8.7 2.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.4 EDN97289.1 - 0.28 9.8 15.1 0.53 8.9 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dynamin_N PF00350.18 EDN97289.1 - 0.31 10.8 0.1 0.31 10.8 0.0 2.4 2 1 0 2 2 2 0 Dynamin family IFT57 PF10498.4 EDN97289.1 - 0.31 9.7 5.5 0.55 8.9 3.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TRAP_alpha PF03896.11 EDN97289.1 - 0.71 8.8 5.9 1.2 8.1 4.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 EDN97289.1 - 1.4 8.3 10.6 2.8 7.4 7.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EDN97289.1 - 4.4 7.6 10.7 9.8 6.5 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EDN97289.1 - 5.8 4.8 9.2 8.9 4.1 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EDN97289.1 - 9.3 4.3 8.4 13 3.8 5.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein RNA_polI_A34 PF08208.6 EDN97290.1 - 1.5e-40 138.9 22.9 1.5e-40 138.9 15.9 4.1 3 2 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 TEX19 PF15553.1 EDN97290.1 - 2.9 7.7 17.8 4.1 7.2 1.7 2.9 2 1 0 2 2 2 0 Testis-expressed protein 19 SHMT PF00464.14 EDN97291.1 - 9.2e-207 686.1 0.0 1.1e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EDN97291.1 - 0.0036 16.1 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Baculo_DNA_bind PF04786.7 EDN97291.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein Asp PF00026.18 EDN97293.1 - 4.2e-105 351.4 0.1 5.2e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN97293.1 - 1.7e-11 44.3 0.0 5e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDN97293.1 - 3.7e-06 27.3 0.1 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDN97293.1 - 2.7e-05 23.7 0.0 0.00043 19.8 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EDN97293.1 - 0.016 15.3 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Prefoldin PF02996.12 EDN97294.1 - 4.9e-28 97.1 0.1 1e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EDN97294.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.5 3 1 0 3 3 3 0 Prefoldin subunit EzrA PF06160.7 EDN97294.1 - 0.018 13.2 3.0 1.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2353 PF09789.4 EDN97294.1 - 0.1 11.8 1.7 0.11 11.6 1.1 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CRAL_TRIO PF00650.15 EDN97295.1 - 5.5e-36 123.4 0.0 7.8e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN97295.1 - 8.8e-09 35.3 1.3 2.6e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDN97295.1 - 0.00069 19.5 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Ferric_reduct PF01794.14 EDN97296.1 - 9.5e-15 54.7 11.4 9.5e-15 54.7 7.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDN97296.1 - 3.7e-10 39.6 0.0 1.4e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN97296.1 - 8.6e-09 35.4 0.0 0.00011 22.1 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF952 PF06108.7 EDN97298.1 - 0.07 12.9 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF952) FAD_binding_4 PF01565.18 EDN97298.1 - 0.13 11.7 0.2 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain Nop PF01798.13 EDN97299.1 - 2.9e-60 201.8 0.1 5.4e-60 201.0 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDN97299.1 - 5.1e-25 87.0 0.0 1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDN97299.1 - 4.4e-22 78.0 0.0 4.4e-22 78.0 0.0 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EDN97299.1 - 0.059 13.0 28.0 0.11 12.1 19.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EDN97299.1 - 0.073 13.0 12.9 0.13 12.2 9.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EDN97299.1 - 7.9 6.2 9.8 15 5.3 6.8 1.5 1 0 0 1 1 1 0 DDHD domain AAA PF00004.24 EDN97300.1 - 1.8e-42 144.6 0.0 3.7e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDN97300.1 - 2.3e-29 101.0 0.1 7.3e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EDN97300.1 - 2.5e-19 68.8 5.4 2.5e-19 68.8 3.7 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.9 EDN97300.1 - 3.1e-06 26.9 0.0 2.3e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN97300.1 - 3.4e-06 27.8 0.1 1.6e-05 25.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EDN97300.1 - 6.1e-06 26.4 0.0 0.0018 18.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN97300.1 - 1.7e-05 24.3 0.0 4.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN97300.1 - 2.5e-05 23.4 0.0 4.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDN97300.1 - 3.8e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDN97300.1 - 4.4e-05 23.4 0.2 0.0082 16.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDN97300.1 - 6.9e-05 21.8 0.0 0.0014 17.6 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EDN97300.1 - 8e-05 22.7 0.0 0.001 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EDN97300.1 - 8.7e-05 22.6 0.0 0.009 16.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 EDN97300.1 - 0.00014 20.7 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EDN97300.1 - 0.0005 19.5 0.1 0.19 11.1 0.1 2.6 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 EDN97300.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN97300.1 - 0.0033 16.5 0.1 0.15 11.0 0.0 2.6 1 1 1 3 3 3 1 Zeta toxin AAA_24 PF13479.1 EDN97300.1 - 0.0044 16.6 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDN97300.1 - 0.01 16.1 0.1 0.028 14.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EDN97300.1 - 0.018 14.7 0.3 0.31 10.7 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 EDN97300.1 - 0.019 14.1 0.1 0.059 12.5 0.0 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EDN97300.1 - 0.022 14.4 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EDN97300.1 - 0.028 14.2 0.1 0.074 12.9 0.0 1.7 2 0 0 2 2 1 0 Torsin PhoH PF02562.11 EDN97300.1 - 0.037 13.2 0.0 0.091 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EDN97300.1 - 0.04 13.5 0.0 0.47 10.1 0.0 2.4 2 1 0 2 2 1 0 NACHT domain ResIII PF04851.10 EDN97300.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EDN97300.1 - 0.046 12.5 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 EDN97300.1 - 0.062 12.4 0.1 7.2 5.6 0.0 2.9 2 1 1 3 3 3 0 KaiC CPT PF07931.7 EDN97300.1 - 0.1 12.2 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EDN97300.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 EDN97300.1 - 0.16 11.9 0.2 3 7.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EDN97301.1 - 1.4e-21 76.2 11.9 1.7e-21 75.9 8.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EDN97301.1 - 0.0014 18.4 5.8 0.0018 17.9 3.6 1.6 1 1 1 2 2 2 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 EDN97301.1 - 0.0047 16.7 10.9 0.32 10.8 2.8 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 EDN97301.1 - 0.0099 15.3 15.0 0.04 13.4 0.2 3.1 2 1 1 3 3 3 2 Septum formation initiator IncA PF04156.9 EDN97301.1 - 0.014 15.0 13.9 0.058 12.9 9.7 1.8 1 1 0 1 1 1 0 IncA protein Lzipper-MIP1 PF14389.1 EDN97301.1 - 0.023 14.7 8.7 0.052 13.6 2.4 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.6 EDN97301.1 - 0.031 14.0 4.6 0.35 10.7 0.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 EDN97301.1 - 0.064 13.6 9.1 0.44 10.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EDN97301.1 - 0.13 11.9 10.5 0.21 11.2 2.8 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HR1 PF02185.11 EDN97301.1 - 0.13 11.9 13.4 0.075 12.7 0.8 3.0 2 2 1 3 3 3 0 Hr1 repeat Snapin_Pallidin PF14712.1 EDN97301.1 - 0.16 12.2 0.2 0.16 12.2 0.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Aida_N PF08910.5 EDN97301.1 - 0.2 11.9 3.5 1.2 9.3 2.3 2.0 1 1 0 1 1 1 0 Aida N-terminus MHC2-interact PF09307.5 EDN97301.1 - 0.22 11.3 5.8 0.54 10.0 1.5 2.2 2 0 0 2 2 2 0 CLIP, MHC2 interacting DUF4201 PF13870.1 EDN97301.1 - 0.22 10.9 8.7 2.2 7.6 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FliD_N PF02465.13 EDN97301.1 - 0.23 11.8 8.6 0.83 10.0 3.4 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PEP-utilisers_N PF05524.8 EDN97301.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal GAS PF13851.1 EDN97301.1 - 0.27 10.3 12.7 0.38 9.9 4.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EDN97301.1 - 0.28 11.4 9.5 0.72 10.1 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 EDN97301.1 - 0.33 10.6 13.2 7.6 6.2 9.2 2.0 1 1 0 1 1 1 0 Prefoldin subunit DUF4140 PF13600.1 EDN97301.1 - 0.36 11.3 0.2 0.36 11.3 0.1 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 EDN97301.1 - 0.36 10.8 4.6 0.68 9.9 3.2 1.5 1 1 0 1 1 1 0 Up-regulated During Septation BLOC1_2 PF10046.4 EDN97301.1 - 0.38 10.9 5.5 5 7.3 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.3 EDN97301.1 - 0.47 10.2 10.7 2.1 8.1 2.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Taxilin PF09728.4 EDN97301.1 - 0.47 9.4 11.6 0.5 9.4 3.2 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF3571 PF12095.3 EDN97301.1 - 0.55 10.4 6.1 1.8 8.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) BRE1 PF08647.6 EDN97301.1 - 0.6 10.1 7.8 0.57 10.1 0.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Enkurin PF13864.1 EDN97301.1 - 0.7 10.1 8.8 5.3 7.3 2.3 2.2 2 0 0 2 2 2 0 Calmodulin-binding DUF848 PF05852.6 EDN97301.1 - 0.73 9.6 8.4 1.9 8.3 1.4 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 EDN97301.1 - 0.83 8.6 11.8 0.52 9.2 3.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EDN97301.1 - 0.88 9.4 13.4 3.3 7.5 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin like Rootletin PF15035.1 EDN97301.1 - 0.99 9.3 8.1 1.7 8.5 5.6 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 EDN97301.1 - 1 9.0 10.3 11 5.6 6.7 2.0 1 1 1 2 2 2 0 Mnd1 family DUF3847 PF12958.2 EDN97301.1 - 1.5 8.6 10.7 3.1 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF106 PF01956.11 EDN97301.1 - 1.6 8.2 5.4 2.4 7.6 3.7 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 M PF02370.11 EDN97301.1 - 2 9.0 11.6 1.8 9.2 1.1 3.5 2 1 1 3 3 2 0 M protein repeat DUF4164 PF13747.1 EDN97301.1 - 2.2 8.4 7.2 4.3 7.5 1.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Tho2 PF11262.3 EDN97301.1 - 2.4 7.1 5.4 1.9 7.4 1.1 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Siah-Interact_N PF09032.6 EDN97301.1 - 4.8 7.3 15.0 1.4 9.0 3.6 2.4 2 1 0 2 2 2 0 Siah interacting protein, N terminal DUF1664 PF07889.7 EDN97301.1 - 5.1 6.9 7.0 3.6 7.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 EDN97301.1 - 5.1 7.1 12.1 11 6.0 4.1 2.1 1 1 1 2 2 2 0 DivIVA protein Spc7 PF08317.6 EDN97301.1 - 6 5.4 13.3 1.1 7.8 0.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Kinesin-relat_1 PF12711.2 EDN97301.1 - 6 7.3 8.2 13 6.2 0.2 2.3 2 0 0 2 2 2 0 Kinesin motor V_ATPase_I PF01496.14 EDN97301.1 - 6.1 4.5 9.6 2.2 6.0 3.5 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 EDN97301.1 - 6.9 6.9 10.9 16 5.6 3.3 2.2 2 0 0 2 2 2 0 Syntaxin DUF4200 PF13863.1 EDN97301.1 - 7.2 6.5 12.9 12 5.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Bromodomain PF00439.20 EDN97303.1 - 7.8e-19 67.3 0.1 2e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EDN97303.1 - 6.6e-07 28.9 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 EDN97305.1 - 2.3e-10 40.5 4.5 3.5e-10 39.9 3.1 1.2 1 0 0 1 1 1 1 VanZ like family ABC_membrane_3 PF13748.1 EDN97305.1 - 0.18 10.7 1.5 0.25 10.3 1.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4401 PF14351.1 EDN97305.1 - 0.19 10.6 3.7 0.25 10.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1754 PF08555.5 EDN97306.1 - 0.054 14.0 17.8 0.081 13.5 12.4 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Rtf2 PF04641.7 EDN97306.1 - 0.069 12.3 7.3 0.069 12.3 5.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger HA2 PF04408.18 EDN97306.1 - 0.14 12.1 1.2 0.15 12.1 0.8 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) BLVR PF06375.6 EDN97306.1 - 0.16 11.7 17.7 0.2 11.4 12.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med19 PF10278.4 EDN97306.1 - 0.17 11.5 12.1 0.17 11.5 8.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Protocadherin PF08374.6 EDN97306.1 - 0.25 10.9 6.5 0.22 11.1 4.5 1.1 1 0 0 1 1 1 0 Protocadherin NST1 PF13945.1 EDN97306.1 - 0.7 9.9 13.0 1 9.4 9.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator TSGP1 PF07771.6 EDN97306.1 - 0.82 9.5 8.4 0.9 9.4 5.8 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 OAD_gamma PF04277.8 EDN97306.1 - 1.3 9.3 4.0 1.6 9.1 2.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Eapp_C PF10238.4 EDN97306.1 - 1.7 8.5 5.6 1.9 8.3 3.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein SR-25 PF10500.4 EDN97306.1 - 6.6 6.1 16.6 7.7 5.9 11.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EDN97306.1 - 8 6.2 11.4 9.4 6.0 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RPAP1_C PF08620.5 EDN97307.1 - 1.4e-28 98.5 0.0 2.8e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EDN97307.1 - 5.3e-19 67.5 7.3 2e-18 65.7 5.1 1.9 2 0 0 2 2 2 1 RPAP1-like, N-terminal HUN PF08729.5 EDN97308.1 - 7e-14 51.4 1.3 9.8e-14 50.9 0.1 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Mito_carr PF00153.22 EDN97309.1 - 1.2e-52 175.5 2.1 4.6e-18 64.7 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane_2 PF12679.2 EDN97309.1 - 0.59 8.9 13.4 1.1 8.0 9.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein E1-E2_ATPase PF00122.15 EDN97309.1 - 1 8.3 4.3 1.6 7.7 3.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Complex1_LYR PF05347.10 EDN97310.1 - 0.16 11.7 0.9 0.34 10.7 0.6 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF2370 PF10176.4 EDN97311.1 - 1.1e-88 296.4 0.0 1.9e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) XPG_I PF00867.13 EDN97312.1 - 3.6e-27 94.2 0.2 9.7e-27 92.8 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EDN97312.1 - 8e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing DUF2962 PF11176.3 EDN97313.1 - 6e-45 152.5 2.0 7.1e-45 152.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 EDN97313.1 - 0.0044 17.7 0.7 0.32 11.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain BamHI PF02923.10 EDN97313.1 - 0.029 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BamHI MAM33 PF02330.11 EDN97314.1 - 2e-31 109.3 1.3 2.6e-31 108.9 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein IBR PF01485.16 EDN97315.1 - 2.1e-22 78.7 46.3 7.9e-12 44.8 5.1 4.6 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EDN97315.1 - 1.2e-05 24.9 44.0 0.00057 19.4 3.5 4.9 3 2 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN97315.1 - 1.3e-05 25.0 8.3 1.3e-05 25.0 5.7 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN97315.1 - 0.00012 21.8 43.0 0.0036 17.0 5.1 3.7 2 1 1 3 3 3 3 Ring finger domain UN_NPL4 PF11543.3 EDN97315.1 - 0.0022 18.2 0.0 0.0062 16.8 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EDN97315.1 - 0.019 14.6 8.7 0.019 14.6 6.0 3.9 3 1 1 4 4 4 0 zinc-RING finger domain AceK PF06315.6 EDN97315.1 - 0.023 12.9 1.6 0.035 12.3 1.1 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-C3HC4_4 PF15227.1 EDN97315.1 - 0.31 10.9 33.8 0.16 11.8 2.8 4.9 3 2 1 4 4 4 0 zinc finger of C3HC4-type, RING BNR_2 PF13088.1 EDN97317.1 - 2.3e-06 27.1 0.1 0.00021 20.6 0.0 2.6 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EDN97317.1 - 0.0072 15.9 11.2 0.049 13.4 0.4 4.1 4 0 0 4 4 4 2 BNR/Asp-box repeat Redoxin PF08534.5 EDN97318.1 - 6.2e-29 100.4 0.0 7.3e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDN97318.1 - 4.6e-05 23.0 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family FRQ PF09421.5 EDN97319.1 - 2.6e-148 495.6 45.6 2e-147 492.6 31.6 2.2 1 1 0 1 1 1 1 Frequency clock protein Leu_zip PF15294.1 EDN97319.1 - 0.029 13.4 0.6 0.05 12.7 0.4 1.3 1 0 0 1 1 1 0 Leucine zipper Acetyltransf_1 PF00583.19 EDN97321.1 - 7.9e-10 38.6 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN97321.1 - 2.7e-09 37.1 0.0 5.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN97321.1 - 5.9e-05 23.1 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN97321.1 - 0.0065 16.3 0.0 0.3 10.9 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.16 EDN97322.1 - 2.9e-198 659.1 0.0 3.4e-198 658.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EDN97322.1 - 0.13 11.6 0.7 0.43 10.0 0.1 2.1 3 0 0 3 3 3 0 Starch synthase catalytic domain Sugarporin_N PF11471.3 EDN97322.1 - 0.14 11.7 0.3 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Adaptin_N PF01602.15 EDN97323.1 - 6.6e-146 486.6 7.5 9e-146 486.2 5.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDN97323.1 - 9.5e-26 90.7 0.5 7.4e-25 87.8 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDN97323.1 - 3.3e-17 62.5 0.2 3.8e-06 27.0 0.0 4.9 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EDN97323.1 - 1.1e-11 43.8 2.4 0.016 15.2 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EDN97323.1 - 0.00025 21.4 0.4 0.88 10.1 0.0 5.2 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.3 EDN97323.1 - 0.00081 18.8 0.1 2 7.7 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Cohesin_HEAT PF12765.2 EDN97323.1 - 0.021 14.7 0.1 9.8 6.2 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CAAP1 PF15335.1 EDN97323.1 - 0.084 13.0 0.5 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 DUF3593 PF12159.3 EDN97324.1 - 0.076 12.8 0.1 0.076 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) BolA PF01722.13 EDN97325.1 - 5.5e-21 74.3 0.0 7.2e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EDN97326.1 - 2.8e-59 200.6 0.0 3.7e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 EDN97327.1 - 1.7e-28 98.2 0.1 2.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EDN97327.1 - 0.0004 18.9 0.1 0.00054 18.5 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family DUF3826 PF12875.2 EDN97327.1 - 0.0042 16.8 0.2 0.15 11.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3826) COG5 PF10392.4 EDN97327.1 - 0.0048 16.8 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ATP-synt_ab PF00006.20 EDN97327.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NYD-SP28_assoc PF14775.1 EDN97327.1 - 0.071 12.8 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain COesterase PF00135.23 EDN97328.1 - 5.6e-78 262.9 0.0 7.8e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN97328.1 - 2.1e-05 24.1 0.6 9e-05 22.1 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TFIIS_C PF01096.13 EDN97329.1 - 1.8e-11 43.4 0.5 1.8e-11 43.4 0.4 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 EDN97329.1 - 0.034 13.5 0.1 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain UPF0547 PF10571.4 EDN97329.1 - 0.036 13.7 0.2 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 EDN97329.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 zinc-finger TusA PF01206.12 EDN97329.1 - 0.1 12.1 0.3 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Sulfurtransferase TusA DUF1610 PF07754.6 EDN97329.1 - 0.11 12.6 1.1 0.3 11.2 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 EDN97329.1 - 0.32 11.3 0.1 0.32 11.3 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger double domain Med3 PF11593.3 EDN97330.1 - 0.05 12.8 0.9 0.051 12.7 0.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF3_N PF09440.5 EDN97331.1 - 3.3e-52 176.1 0.4 8.2e-52 174.8 0.2 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EDN97331.1 - 1.1e-14 54.6 0.6 8.1e-14 51.8 0.0 2.5 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.4 EDN97331.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 PCI_Csn8 PF10075.4 EDN97331.1 - 0.024 14.4 0.1 0.059 13.1 0.1 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EDN97332.1 - 9.2e-08 32.2 0.4 9.7e-08 32.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) HSCB_C PF07743.8 EDN97332.1 - 0.13 12.7 0.2 0.14 12.6 0.2 1.2 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain ARID PF01388.16 EDN97333.1 - 1.2e-20 73.1 0.9 2.9e-20 71.9 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF4579 PF15158.1 EDN97333.1 - 0.1 12.1 0.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) EVE PF01878.13 EDN97334.1 - 6e-22 78.2 1.1 4.9e-17 62.2 0.4 2.5 1 1 1 2 2 2 2 EVE domain FlgH PF02107.11 EDN97334.1 - 0.099 12.2 7.2 0.15 11.5 5.0 1.4 1 0 0 1 1 1 0 Flagellar L-ring protein RNA_pol_Rbc25 PF08292.7 EDN97334.1 - 1.1 9.4 5.5 15 5.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Dicty_REP PF05086.7 EDN97334.1 - 1.5 6.4 9.3 1.8 6.2 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.6 EDN97334.1 - 2.1 6.5 8.5 2.5 6.3 5.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.5 EDN97334.1 - 6 5.1 7.2 6.5 5.0 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Xpo1 PF08389.7 EDN97335.1 - 1.5e-05 24.9 0.1 8.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EDN97335.1 - 0.0013 18.5 0.6 0.011 15.6 0.1 2.8 1 1 1 2 2 2 1 Importin-beta N-terminal domain Fungal_trans_2 PF11951.3 EDN97337.1 - 1.1e-09 37.3 0.2 3.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN97337.1 - 0.059 13.2 3.5 0.12 12.2 2.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEMspv1-c74-12 PF11044.3 EDN97338.1 - 0.035 13.6 0.2 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sec23_trunk PF04811.10 EDN97339.1 - 4.9e-71 238.9 0.0 7.2e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN97339.1 - 4.8e-24 83.7 0.0 1.8e-22 78.6 0.0 2.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDN97339.1 - 3.3e-19 69.1 0.1 7.1e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDN97339.1 - 1.8e-17 62.5 5.2 3.2e-17 61.7 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDN97339.1 - 2.3e-07 30.3 0.0 5.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 EDN97339.1 - 0.22 11.5 0.7 0.5 10.3 0.5 1.5 1 0 0 1 1 1 0 Testis-expressed 12 Pkinase PF00069.20 EDN97341.1 - 5.2e-74 248.6 0.0 6.8e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97341.1 - 1.1e-31 109.8 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN97341.1 - 0.00056 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN97341.1 - 0.002 17.2 0.1 0.0036 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN97341.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN97341.1 - 0.051 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cellulase PF00150.13 EDN97342.1 - 5.6e-13 48.7 3.3 1.9e-09 37.1 1.1 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EDN97342.1 - 0.0043 16.2 0.9 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase TPR_11 PF13414.1 EDN97343.1 - 1.5e-41 139.8 31.9 6.9e-07 28.8 0.1 11.9 9 2 2 11 11 11 9 TPR repeat TPR_16 PF13432.1 EDN97343.1 - 9.6e-35 118.5 38.0 1.9e-07 31.5 0.6 12.9 12 2 2 14 14 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97343.1 - 7e-27 91.4 29.5 0.036 14.7 0.0 13.9 10 3 4 14 14 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EDN97343.1 - 7.6e-27 91.7 29.3 0.00017 21.0 0.2 13.1 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.12 EDN97343.1 - 5.7e-26 88.3 47.7 0.0015 18.2 0.2 15.5 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_17 PF13431.1 EDN97343.1 - 7.3e-24 81.9 9.8 0.016 15.3 0.3 14.4 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDN97343.1 - 3.8e-23 81.5 16.5 0.0048 17.2 1.2 11.7 10 2 2 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN97343.1 - 6.4e-21 74.0 35.7 3.4e-05 23.6 0.1 12.0 8 3 6 14 14 14 9 Tetratricopeptide repeat TPR_8 PF13181.1 EDN97343.1 - 2.4e-19 67.5 22.5 0.026 14.2 0.0 11.8 12 1 1 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.1 EDN97343.1 - 3.1e-15 54.7 19.2 0.21 11.4 0.1 12.4 11 2 2 13 13 12 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDN97343.1 - 4.4e-10 39.3 26.3 5.3 7.7 0.2 13.2 16 0 0 16 16 13 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN97343.1 - 0.0024 17.6 15.3 4.1 7.3 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Tcf25 PF04910.9 EDN97343.1 - 0.0027 16.6 0.0 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Rapsyn_N PF10579.4 EDN97343.1 - 0.061 13.1 0.7 13 5.6 0.0 4.1 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 EDN97343.1 - 0.33 10.8 8.4 6.2 6.7 0.3 5.7 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Mid2 PF04478.7 EDN97345.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM51 PF15345.1 EDN97345.1 - 0.0033 17.1 0.2 0.0053 16.4 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.11 EDN97345.1 - 0.0063 14.8 0.1 0.0094 14.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 EDN97345.1 - 0.0069 16.7 1.1 0.025 14.9 0.2 2.1 2 0 0 2 2 2 1 Alphavirus glycoprotein J DUF1191 PF06697.7 EDN97345.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 EDN97345.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Plasmodium_Vir PF05795.6 EDN97345.1 - 0.32 10.1 1.2 0.48 9.5 0.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase PF00069.20 EDN97346.1 - 1.1e-67 227.9 0.0 1.4e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97346.1 - 3.2e-28 98.5 0.0 4.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN97346.1 - 9.4e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN97346.1 - 0.00018 21.3 0.1 0.00035 20.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN97346.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDN97346.1 - 0.048 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Phage_lambda_P PF06992.6 EDN97347.1 - 0.057 12.6 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 Replication protein P U3_assoc_6 PF08640.6 EDN97348.1 - 2.1e-27 94.6 0.6 5.4e-27 93.3 0.1 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EDN97348.1 - 0.003 16.5 0.0 0.11 11.3 0.0 1.7 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 EDN97348.1 - 0.0081 15.9 0.2 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EDN97348.1 - 0.043 14.4 0.5 0.87 10.3 0.1 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Frag1 PF10277.4 EDN97349.1 - 7e-42 143.3 10.1 7e-42 143.3 7.0 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Abhydrolase_6 PF12697.2 EDN97350.1 - 2.1e-11 44.1 0.2 3.6e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN97350.1 - 3.4e-11 43.0 0.0 6.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDN97350.1 - 3.3e-08 32.4 0.0 0.00012 20.6 0.0 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EDN97350.1 - 3e-06 26.8 0.2 1.5e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 EDN97350.1 - 0.00049 18.7 0.0 0.00083 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EDN97350.1 - 0.0011 18.1 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EDN97350.1 - 0.012 15.3 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAP2 PF01569.16 EDN97352.1 - 1.5e-12 47.3 5.8 1.5e-12 47.3 4.0 2.8 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EDN97352.1 - 1.7e-06 27.6 8.1 1.7e-06 27.6 5.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EDN97352.1 - 3.4 7.9 9.1 2.4 8.5 1.2 2.9 2 1 0 3 3 3 0 PAP2 superfamily C-terminal RF-1 PF00472.15 EDN97353.1 - 9.4e-10 38.3 5.3 9.4e-10 38.3 3.7 2.3 1 1 1 2 2 2 1 RF-1 domain Hyccin PF09790.4 EDN97353.1 - 0.0099 14.7 0.2 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Hyccin LMF1 PF06762.9 EDN97353.1 - 0.092 11.5 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipase maturation factor RRM_1 PF00076.17 EDN97354.1 - 3e-11 42.7 0.0 5.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN97354.1 - 3.3e-07 30.1 0.0 6.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN97354.1 - 0.0067 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.8 EDN97355.1 - 1.6e-14 53.5 1.9 1.4e-10 40.6 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF685 PF05085.7 EDN97355.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF685) NAD_binding_6 PF08030.7 EDN97356.1 - 2e-20 73.2 0.0 3.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN97356.1 - 1.7e-14 53.9 13.2 3.7e-14 52.8 9.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDN97356.1 - 7.6e-10 38.6 0.6 5.9e-09 35.7 0.1 2.5 2 2 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EDN97356.1 - 0.00089 19.8 0.0 0.41 11.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DNA_pol_A_exo1 PF01612.15 EDN97357.1 - 1.3e-40 138.7 0.1 2.2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EDN97357.1 - 8.4e-26 90.1 0.1 3.6e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EDN97357.1 - 6.2e-13 48.2 0.0 1.8e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.7 EDN97358.1 - 3.6e-30 103.6 1.5 4.2e-30 103.4 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EDN97358.1 - 0.0015 18.4 0.5 0.004 17.1 0.4 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EDN97358.1 - 0.0035 17.0 3.9 0.079 12.7 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 EDN97358.1 - 0.095 12.8 0.3 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.11 EDN97358.1 - 0.15 12.0 1.8 0.44 10.5 1.2 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.4 EDN97358.1 - 0.16 12.0 1.7 2.9 7.9 1.2 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EDN97358.1 - 1.6 8.8 5.8 2.4 8.2 0.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Gpi1 PF05024.10 EDN97359.1 - 1.5e-65 220.4 9.9 2.3e-65 219.8 6.8 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) ISG65-75 PF11727.3 EDN97360.1 - 0.008 15.2 8.8 0.0098 14.9 6.1 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein MCP_N PF05581.7 EDN97360.1 - 0.078 13.1 0.6 0.11 12.7 0.4 1.3 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus Cmyb_C PF09316.5 EDN97360.1 - 0.091 12.4 0.7 0.14 11.8 0.4 1.4 1 1 0 1 1 1 0 C-myb, C-terminal DUF2992 PF11208.3 EDN97360.1 - 0.28 11.0 4.5 0.35 10.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF883 PF05957.8 EDN97360.1 - 1 9.7 7.9 0.61 10.5 2.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_L6e PF01159.14 EDN97360.1 - 3.5 7.9 5.6 1.5 9.1 1.8 1.8 1 1 1 2 2 2 0 Ribosomal protein L6e YtxH PF12732.2 EDN97360.1 - 9 6.7 11.4 1.4 9.3 1.5 2.3 1 1 1 2 2 2 0 YtxH-like protein Glyco_hydro_76 PF03663.9 EDN97361.1 - 5.1e-158 526.3 24.7 6.5e-158 525.9 17.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 SAYSvFN PF10260.4 EDN97361.1 - 0.12 12.1 0.2 0.39 10.5 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) TPPII_N PF12583.3 EDN97361.1 - 1.5 8.9 4.4 0.54 10.3 1.1 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal adh_short PF00106.20 EDN97366.1 - 2.3e-24 86.1 0.0 4.1e-24 85.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN97366.1 - 7.2e-23 81.5 0.1 1.6e-21 77.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN97366.1 - 8.4e-10 38.5 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EDN97366.1 - 0.00011 21.4 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EDN97366.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UPF0182 PF03699.8 EDN97367.1 - 2 6.2 6.9 3.2 5.5 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Mito_carr PF00153.22 EDN97368.1 - 7.1e-47 157.0 1.9 1.3e-18 66.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 EDN97369.1 - 5e-67 225.7 0.0 9e-67 224.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EDN97369.1 - 1.6e-64 217.2 2.0 2.4e-64 216.7 0.8 1.7 1 1 1 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EDN97369.1 - 1.3e-12 47.3 0.0 3.9e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDN97369.1 - 0.00021 20.2 0.3 0.0015 17.3 0.0 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EDN97369.1 - 0.00026 20.8 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Hydrophobin PF01185.13 EDN97370.1 - 7.4e-08 32.7 10.6 2.5e-07 31.0 7.3 1.7 1 1 0 1 1 1 1 Fungal hydrophobin SURF6 PF04935.7 EDN97372.1 - 7.6e-52 175.6 31.2 7.6e-52 175.6 21.7 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EDN97372.1 - 5e-05 23.2 5.6 5e-05 23.2 3.9 7.2 8 1 0 8 8 8 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.6 EDN97373.1 - 1.7e-65 220.9 0.1 2.1e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EDN97374.1 - 6e-10 39.2 0.9 8.8e-10 38.7 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EDN97374.1 - 0.00057 19.8 1.3 0.0013 18.6 0.7 1.6 1 1 1 2 2 2 1 Acyl-carrier Fer4 PF00037.22 EDN97375.1 - 1.5e-13 49.6 16.5 5.5e-08 32.0 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EDN97375.1 - 3.5e-12 46.5 10.5 5.8e-12 45.8 7.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDN97375.1 - 1.9e-09 37.1 22.1 5.7e-08 32.4 8.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDN97375.1 - 2.1e-09 37.4 10.7 4.1e-09 36.5 7.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EDN97375.1 - 2.6e-09 37.6 7.6 0.00022 21.8 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EDN97375.1 - 1e-08 34.8 31.9 1.4e-05 24.8 8.6 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDN97375.1 - 1.1e-07 31.7 20.5 1.9e-05 24.5 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDN97375.1 - 1.4e-07 31.0 14.7 0.00045 19.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EDN97375.1 - 2.7e-07 30.1 17.1 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EDN97375.1 - 5.5e-06 26.2 12.7 0.00059 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EDN97375.1 - 5.8e-06 26.5 9.5 0.00069 19.9 7.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDN97375.1 - 3.5e-05 24.1 9.5 0.013 15.8 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EDN97375.1 - 0.0083 16.4 15.1 0.31 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EDN97375.1 - 0.018 15.5 13.3 0.3 11.6 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EDN97375.1 - 0.076 13.6 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain LEA_4 PF02987.11 EDN97375.1 - 0.094 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein c-SKI_SMAD_bind PF08782.5 EDN97375.1 - 0.12 12.4 4.9 0.14 12.3 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain CarbpepA_inh PF02977.10 EDN97380.1 - 0.19 11.3 0.6 0.29 10.7 0.4 1.2 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor DDE_1 PF03184.14 EDN97383.1 - 2.2e-51 174.0 0.0 5.1e-51 172.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97383.1 - 4.6e-10 39.1 1.0 1.2e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN97383.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN97383.1 - 0.0047 16.7 6.0 0.012 15.4 4.2 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDN97383.1 - 0.078 13.2 0.6 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) SLAIN PF15301.1 EDN97384.1 - 0.013 14.6 9.1 0.015 14.5 6.3 1.0 1 0 0 1 1 1 0 SLAIN motif-containing family WSC PF01822.14 EDN97385.1 - 3.4e-08 33.2 3.6 3.4e-08 33.2 2.5 3.0 3 0 0 3 3 3 1 WSC domain CBM_4_9 PF02018.12 EDN97385.1 - 0.0011 18.9 0.1 0.0026 17.7 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain zf-C2H2 PF00096.21 EDN97386.1 - 4.8e-11 42.3 12.3 0.005 17.0 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN97386.1 - 1.5e-08 34.4 10.5 0.042 14.1 1.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN97386.1 - 2.2e-05 24.1 5.1 0.092 12.6 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EDN97386.1 - 6.9e-05 22.8 3.8 0.43 10.8 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN97386.1 - 0.0005 20.1 2.7 0.06 13.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EDN97386.1 - 0.00069 19.6 3.5 0.011 15.8 1.7 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EDN97386.1 - 0.0058 16.8 0.5 0.0058 16.8 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 EDN97386.1 - 0.029 14.4 5.5 1.4 9.1 3.9 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.17 EDN97386.1 - 0.082 12.6 0.6 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 EDN97386.1 - 0.4 10.9 7.7 8.5 6.8 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NPP1 PF05630.6 EDN97387.1 - 7.9e-55 185.8 0.0 9.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Acyl_transf_3 PF01757.17 EDN97390.1 - 5.4e-35 120.8 30.9 1.5e-34 119.4 21.3 1.7 1 1 0 1 1 1 1 Acyltransferase family eIF2A PF08662.6 EDN97393.1 - 1.7e-79 266.0 0.2 2.3e-78 262.3 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EDN97393.1 - 1.3e-06 27.9 2.4 0.57 10.1 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat CDV3 PF15359.1 EDN97393.1 - 0.0085 16.1 0.4 0.0085 16.1 0.3 2.7 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 MFS_1 PF07690.11 EDN97394.1 - 1.7e-35 122.3 32.9 1.7e-35 122.3 22.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN97394.1 - 4.2e-09 35.5 10.2 4.2e-09 35.5 7.1 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1228 PF06779.9 EDN97394.1 - 0.02 14.9 0.9 0.02 14.9 0.6 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Glyco_hydro_43 PF04616.9 EDN97397.1 - 9e-30 103.7 5.3 1.1e-29 103.4 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ECH PF00378.15 EDN97398.1 - 1.6e-45 155.1 0.1 3.7e-42 144.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF222 PF02720.12 EDN97398.1 - 0.023 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) Ank_2 PF12796.2 EDN97399.1 - 2.2e-18 66.3 0.0 2.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN97399.1 - 4.6e-17 61.6 1.2 1.9e-09 37.4 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EDN97399.1 - 7.5e-16 57.0 0.3 8.4e-09 34.8 0.3 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EDN97399.1 - 6.3e-13 48.8 0.1 3.9e-09 36.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN97399.1 - 1.6e-12 46.3 0.0 1.1e-05 25.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat DUF2958 PF11171.3 EDN97400.1 - 0.61 9.9 9.5 17 5.2 0.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2958) Apc1 PF12859.2 EDN97401.1 - 5.5e-29 100.4 0.1 1.9e-28 98.7 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EDN97401.1 - 2.6e-05 24.2 0.9 0.3 11.3 0.1 4.7 4 0 0 4 4 4 2 Proteasome/cyclosome repeat DUF1871 PF08958.5 EDN97401.1 - 0.033 14.2 0.1 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) Cu-oxidase_3 PF07732.10 EDN97402.1 - 2.6e-43 146.5 5.7 2.5e-41 140.1 0.4 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN97402.1 - 5e-41 139.4 9.8 1.3e-40 138.0 0.6 3.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EDN97402.1 - 1.1e-35 122.9 0.4 3.7e-35 121.1 0.3 1.9 1 0 0 1 1 1 1 Multicopper oxidase Macoilin PF09726.4 EDN97402.1 - 6.3 4.9 12.5 8.7 4.4 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein COesterase PF00135.23 EDN97405.1 - 2.8e-101 339.8 0.0 3.8e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN97405.1 - 2.9e-05 23.7 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 EDN97407.1 - 5.6e-23 81.6 0.1 6.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN97407.1 - 6.2e-13 49.0 0.0 8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN97407.1 - 1.7e-06 27.8 0.1 4.2e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN97407.1 - 0.0025 17.8 0.2 0.0045 17.0 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN97407.1 - 0.0026 17.5 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EDN97407.1 - 0.021 13.9 0.3 0.03 13.4 0.2 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 EDN97407.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1744 PF08490.7 EDN97408.1 - 9.5e-153 508.4 0.0 1.4e-152 507.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EDN97408.1 - 1.2e-63 214.9 0.1 2.5e-63 213.8 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EDN97408.1 - 4.2e-24 85.1 0.4 1.6e-23 83.2 0.3 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EDN97408.1 - 8.2e-09 35.3 0.1 2.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EDN97408.1 - 2.7e-06 27.2 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EDN97409.1 - 2.9e-16 59.1 0.0 3.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF4378 PF14309.1 EDN97414.1 - 0.065 13.2 0.1 0.085 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Ribosomal_S2 PF00318.15 EDN97415.1 - 9.3e-49 165.5 0.0 2.4e-48 164.1 0.0 1.7 2 1 0 2 2 2 1 Ribosomal protein S2 CBS PF00571.23 EDN97416.1 - 1.4e-40 136.8 9.5 4.8e-11 42.2 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EDN97416.1 - 3.5e-11 42.6 0.0 1.3e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 PB1 domain zf-H2C2_2 PF13465.1 EDN97417.1 - 1.8e-09 37.4 13.4 0.00033 20.7 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN97417.1 - 7.9e-08 32.2 26.2 0.001 19.2 6.3 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN97417.1 - 0.0012 18.9 23.0 0.3 11.5 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger AT_hook PF02178.14 EDN97417.1 - 0.81 9.5 5.2 2.9 7.8 3.6 2.0 1 0 0 1 1 1 0 AT hook motif zf-C2H2_6 PF13912.1 EDN97417.1 - 4.8 7.2 12.2 0.57 10.1 0.5 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Nucleoplasmin PF03066.10 EDN97418.1 - 0.12 11.8 6.9 0.12 11.8 4.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EDN97418.1 - 0.16 12.2 6.8 0.16 12.2 4.7 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 EDN97418.1 - 0.65 10.1 4.8 0.75 9.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Spt5_N PF11942.3 EDN97418.1 - 1 10.0 10.9 1.2 9.7 7.6 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EDN97418.1 - 1.9 8.8 5.9 2.1 8.6 4.1 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EDN97418.1 - 7.8 5.0 9.5 8.8 4.9 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ubiquitin PF00240.18 EDN97420.1 - 3.4e-21 74.3 0.0 6.9e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN97420.1 - 4.2e-11 42.3 0.0 7.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Spore_YabQ PF09578.5 EDN97421.1 - 0.039 13.9 0.2 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) MFS_1 PF07690.11 EDN97423.1 - 6.7e-44 150.0 30.0 6.7e-44 150.0 20.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN97423.1 - 2.2e-08 32.7 4.4 3.8e-08 31.9 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN97423.1 - 3.1e-07 29.3 28.1 7.3e-07 28.1 19.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 EDN97423.1 - 9.7e-05 22.0 1.5 9.7e-05 22.0 1.1 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) Fungal_trans PF04082.13 EDN97424.1 - 8.7e-09 34.6 0.0 1.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN97424.1 - 2e-08 34.0 11.3 3.9e-08 33.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.5 EDN97424.1 - 1 9.3 6.0 3.1 7.8 4.1 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding CBS PF00571.23 EDN97425.1 - 4.9e-17 61.4 0.3 0.00065 19.4 0.0 5.4 5 0 0 5 5 5 4 CBS domain HEAT PF02985.17 EDN97426.1 - 3.3e-20 70.2 9.6 0.00091 19.1 0.0 11.2 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.1 EDN97426.1 - 3.3e-19 68.9 9.4 7.3e-08 32.5 0.2 8.5 5 3 4 9 9 8 6 HEAT repeats HEAT_EZ PF13513.1 EDN97426.1 - 1e-16 60.8 19.4 7.5e-08 32.6 0.1 9.8 6 3 5 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN97426.1 - 7.3e-11 42.3 0.1 0.035 14.4 0.0 6.7 4 2 5 9 9 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDN97426.1 - 2.5e-08 33.5 1.7 0.016 14.5 0.1 5.6 6 1 0 7 7 7 2 CLASP N terminal RIX1 PF08167.7 EDN97426.1 - 2.8e-07 30.3 0.0 0.11 12.1 0.0 4.5 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EDN97426.1 - 1.6e-06 27.1 2.2 4.4e-05 22.3 0.1 3.4 2 2 2 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 EDN97426.1 - 0.00036 20.4 5.0 0.52 10.1 0.1 4.5 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EDN97426.1 - 0.00083 17.7 0.3 0.052 11.8 0.0 2.8 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit TFCD_C PF12612.3 EDN97426.1 - 0.0085 15.5 0.1 2.7 7.3 0.0 3.9 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal Xpo1 PF08389.7 EDN97426.1 - 0.0092 15.8 0.0 1.9 8.3 0.0 3.8 2 1 1 3 3 3 1 Exportin 1-like protein DNA_alkylation PF08713.6 EDN97426.1 - 0.012 15.1 0.0 0.41 10.1 0.0 2.9 3 0 0 3 3 3 0 DNA alkylation repair enzyme V-ATPase_H_N PF03224.9 EDN97426.1 - 0.026 13.6 1.4 3.7 6.5 0.0 3.4 2 1 0 2 2 2 0 V-ATPase subunit H IBN_N PF03810.14 EDN97426.1 - 0.087 12.7 1.3 0.3 11.0 0.1 2.6 2 1 1 3 3 3 0 Importin-beta N-terminal domain DUF3385 PF11865.3 EDN97426.1 - 0.096 12.6 2.8 22 4.9 0.0 4.6 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) Arm PF00514.18 EDN97426.1 - 0.21 11.4 14.4 1.1 9.1 0.0 5.7 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat DDE_1 PF03184.14 EDN97427.1 - 8e-51 172.2 0.0 1.4e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97427.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97427.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97427.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN97427.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle PAS_9 PF13426.1 EDN97428.1 - 1.3e-28 99.4 0.0 5e-15 55.7 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EDN97428.1 - 3.6e-17 62.2 0.0 2.5e-11 43.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 EDN97428.1 - 1.4e-15 56.3 5.8 3.1e-15 55.2 4.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EDN97428.1 - 4.7e-12 45.6 0.0 8.9e-06 25.4 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EDN97428.1 - 1.7e-09 37.6 3.3 0.0011 18.9 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EDN97428.1 - 1.7e-07 31.2 0.0 0.037 14.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EDN97428.1 - 0.064 13.1 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 PAS domain Lamprin PF06403.6 EDN97429.1 - 1.2 8.9 12.8 1.6 8.4 8.8 1.3 1 0 0 1 1 1 0 Lamprin GatB_N PF02934.10 EDN97431.1 - 2.4e-89 299.0 0.0 2.7e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 GatB/GatE catalytic domain Fzo_mitofusin PF04799.8 EDN97432.1 - 0.0015 17.9 0.2 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 fzo-like conserved region DUF3995 PF13160.1 EDN97432.1 - 0.039 13.9 0.2 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) PVL_ORF50 PF07768.6 EDN97432.1 - 5.5 7.0 16.2 23 5.0 8.8 2.7 2 0 0 2 2 2 0 PVL ORF-50-like family WD40 PF00400.27 EDN97434.1 - 0.0048 16.7 0.4 0.061 13.2 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat HAD_2 PF13419.1 EDN97435.1 - 4.5e-30 105.1 0.0 5.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN97435.1 - 4.4e-05 23.1 0.0 7.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN97435.1 - 0.017 15.5 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4525 PF15027.1 EDN97435.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) HNH PF01844.18 EDN97436.1 - 0.00011 22.0 1.8 0.00024 20.9 1.3 1.6 1 0 0 1 1 1 1 HNH endonuclease HeLo PF14479.1 EDN97437.1 - 1.4e-40 139.3 0.2 3.2e-40 138.1 0.1 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation UQ_con PF00179.21 EDN97437.1 - 2.5e-24 85.3 0.0 5.5e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Zn_clus PF00172.13 EDN97437.1 - 0.002 18.0 9.3 0.0038 17.0 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec7 PF01369.15 EDN97440.1 - 6.2e-44 149.9 0.0 2.2e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EDN97440.1 - 1.2e-16 60.9 0.0 3.1e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PLAC9 PF15205.1 EDN97441.1 - 0.14 12.4 0.1 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Placenta-specific protein 9 DUF2630 PF10944.3 EDN97441.1 - 0.25 11.4 4.7 4.7 7.3 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2630) Nop14 PF04147.7 EDN97442.1 - 0.0029 15.6 1.7 0.0023 15.9 1.2 1.1 1 0 0 1 1 1 1 Nop14-like family TMP_2 PF06791.8 EDN97444.1 - 0.0044 16.6 1.2 0.23 11.0 0.0 2.2 2 0 0 2 2 2 2 Prophage tail length tape measure protein DUF986 PF06173.7 EDN97444.1 - 0.072 12.8 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF986) DUF1996 PF09362.5 EDN97444.1 - 0.077 12.6 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1996) Ribosomal_S30AE PF02482.14 EDN97444.1 - 0.28 11.6 2.6 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Prominin PF05478.6 EDN97444.1 - 1.1 6.6 10.0 0.036 11.6 2.3 1.8 3 0 0 3 3 3 0 Prominin CENP-Q PF13094.1 EDN97444.1 - 4 7.4 15.6 0.28 11.2 1.4 2.7 2 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Bact_transglu_N PF08379.5 EDN97445.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial transglutaminase-like N-terminal region DnaJ PF00226.26 EDN97445.1 - 0.026 14.2 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Wzz PF02706.10 EDN97445.1 - 0.038 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Chain length determinant protein DUF3373 PF11853.3 EDN97447.1 - 0.17 10.3 0.5 0.16 10.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HTH_Tnp_Tc5 PF03221.11 EDN97448.1 - 9.1e-15 54.2 0.0 1.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN97448.1 - 5.7e-09 35.4 1.3 1.6e-08 33.9 0.2 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF972 PF06156.8 EDN97449.1 - 0.0053 17.0 6.3 0.0053 17.0 4.4 5.5 4 2 2 6 6 6 2 Protein of unknown function (DUF972) Calici_MSP PF05752.6 EDN97449.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.2 3 0 0 3 3 3 0 Calicivirus minor structural protein IncA PF04156.9 EDN97449.1 - 0.2 11.2 51.2 0.14 11.7 7.1 4.5 3 1 1 4 4 4 0 IncA protein DUF489 PF04356.7 EDN97449.1 - 0.39 10.2 7.4 0.14 11.7 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF1664 PF07889.7 EDN97449.1 - 0.43 10.3 25.6 0.064 13.0 1.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 EDN97449.1 - 1.6 7.9 22.8 0.77 8.9 2.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EDN97449.1 - 1.7 8.4 54.9 0.025 14.4 7.8 7.6 7 1 0 8 8 8 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EDN97449.1 - 2.6 7.8 26.7 0.038 13.8 1.8 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aldose_epim PF01263.15 EDN97451.1 - 1.3e-41 142.6 0.2 2.3e-41 141.8 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Acyl-CoA_dh_1 PF00441.19 EDN97451.1 - 4.1e-41 140.5 0.1 7.3e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN97451.1 - 2.1e-20 71.9 0.3 4.9e-20 70.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN97451.1 - 1.8e-16 60.6 0.0 3.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN97451.1 - 2.6e-07 30.9 0.0 7.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 EDN97451.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Glyco_hydro_16 PF00722.16 EDN97452.1 - 4.5e-07 29.3 0.0 1.8e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 KAR9 PF08580.5 EDN97452.1 - 2.4 6.3 4.0 3.1 5.9 2.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Acetyltransf_1 PF00583.19 EDN97453.1 - 2.7e-08 33.7 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN97453.1 - 2.8e-07 30.5 0.1 5.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN97453.1 - 2e-05 24.2 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein GETHR PF05671.6 EDN97453.1 - 2.4e-05 23.3 52.4 0.057 12.5 8.7 3.8 1 1 1 3 3 3 3 GETHR pentapeptide repeat (5 copies) Acetyltransf_9 PF13527.1 EDN97453.1 - 3.5e-05 23.6 0.3 6.2e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN97453.1 - 0.00028 20.9 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hid1 PF12722.2 EDN97453.1 - 1.9 6.0 4.8 2.2 5.8 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 EDN97453.1 - 4.2 5.8 7.5 5.2 5.5 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 EDN97453.1 - 4.8 6.3 22.5 6.7 5.8 15.6 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 EDN97453.1 - 9.8 5.2 14.3 13 4.8 9.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2276 PF10040.4 EDN97458.1 - 0.034 14.3 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) zf-H2C2 PF09337.5 EDN97460.1 - 5e-20 70.6 5.5 1e-19 69.6 3.8 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EDN97460.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDN97460.1 - 0.0044 16.9 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN97460.1 - 0.016 15.4 0.0 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN97460.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.19 EDN97461.1 - 1.6e-140 468.9 4.2 1.8e-140 468.7 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EDN97461.1 - 0.095 12.5 0.6 0.69 9.7 0.1 2.5 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) GMC_oxred_N PF00732.14 EDN97463.1 - 9.5e-29 100.4 0.0 6.3e-27 94.4 0.0 2.8 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN97463.1 - 5.6e-26 91.5 0.0 9.5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EDN97463.1 - 0.0021 18.0 0.2 0.0062 16.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN97463.1 - 0.0031 17.4 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDN97463.1 - 0.03 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EDN97463.1 - 0.083 11.9 0.2 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EDN97463.1 - 0.091 11.5 1.5 0.25 10.1 0.2 2.3 2 1 0 2 2 2 0 FAD binding domain DUF3934 PF13070.1 EDN97465.1 - 0.31 11.3 1.6 0.39 10.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) Oxidored_FMN PF00724.15 EDN97466.1 - 8e-42 143.4 0.0 1e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EDN97466.1 - 0.037 13.3 0.0 11 5.2 0.0 2.8 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Dus PF01207.12 EDN97466.1 - 0.059 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF849 PF05853.7 EDN97466.1 - 0.13 11.0 0.3 0.98 8.2 0.0 2.3 1 1 1 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Lipase_GDSL PF00657.17 EDN97467.1 - 9.3e-08 32.1 4.5 1.4e-06 28.2 3.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDN97467.1 - 1.6e-07 31.6 0.7 2.3e-07 31.1 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DJ-1_PfpI PF01965.19 EDN97470.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3029 PF11230.3 EDN97470.1 - 0.0022 16.2 0.0 0.0036 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3029) GATase_3 PF07685.9 EDN97470.1 - 0.0045 16.5 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EDN97470.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUF239 PF03080.10 EDN97470.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF239) DUF4066 PF13278.1 EDN97470.1 - 0.065 12.5 0.0 0.092 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative amidotransferase Zn_clus PF00172.13 EDN97472.1 - 7.8e-09 35.3 8.5 1.5e-08 34.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN97472.1 - 0.003 16.2 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF155 PF02582.9 EDN97476.1 - 1.2e-42 145.8 0.0 1.5e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Amidohydro_5 PF13594.1 EDN97476.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Clathrin PF00637.15 EDN97477.1 - 1e-13 51.1 0.1 3.5e-11 42.8 0.0 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS Abhydrolase_6 PF12697.2 EDN97478.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EDN97478.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SURF1 PF02104.10 EDN97480.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 SURF1 family RCC1 PF00415.13 EDN97487.1 - 1.7e-28 98.5 4.4 4.8e-05 23.4 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN97487.1 - 1.9e-12 46.4 21.1 7e-09 35.0 0.0 6.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EDN97488.1 - 6.4e-32 110.4 3.0 1.1e-31 109.6 1.2 2.1 2 0 0 2 2 2 1 Sec34-like family CBF PF03914.12 EDN97488.1 - 0.057 12.8 1.1 3.1 7.2 0.0 3.0 2 1 0 2 2 2 0 CBF/Mak21 family Bromodomain PF00439.20 EDN97489.1 - 2.2e-36 123.6 4.6 4.2e-18 65.0 0.2 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EDN97489.1 - 2.8e-12 46.4 0.9 2.8e-12 46.4 0.6 2.0 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.9 EDN97489.1 - 0.094 10.7 7.5 0.15 10.0 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EDN97489.1 - 0.14 11.6 10.7 0.36 10.3 7.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin eIF-3c_N PF05470.7 EDN97489.1 - 0.74 7.8 11.5 0.21 9.6 4.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AT_hook PF02178.14 EDN97489.1 - 0.98 9.3 7.3 0.14 11.8 1.0 2.7 2 0 0 2 2 2 0 AT hook motif DNA_pol_phi PF04931.8 EDN97489.1 - 8.1 4.0 12.1 14 3.3 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.5 EDN97489.1 - 8.5 6.6 19.6 10 6.4 11.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OTU PF02338.14 EDN97490.1 - 1.7e-09 38.3 0.0 3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDN97490.1 - 0.0097 15.2 0.0 0.067 12.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain Mito_carr PF00153.22 EDN97491.1 - 3e-64 212.7 2.5 4.6e-22 77.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_72 PF03198.9 EDN97492.1 - 6.4e-135 449.1 4.7 9.3e-135 448.6 3.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EDN97492.1 - 7.1e-26 90.5 6.7 7.1e-26 90.5 4.7 2.2 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.10 EDN97496.1 - 0 1471.7 0.0 0 1471.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDN97496.1 - 1.3e-38 131.5 0.3 2.8e-38 130.4 0.2 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EDN97497.1 - 1.8e-31 109.4 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDN97497.1 - 0.00047 18.5 0.0 0.00076 17.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EDN97497.1 - 0.011 14.3 0.0 0.086 11.3 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydro_17 PF00332.13 EDN97499.1 - 5.1e-09 35.5 1.7 6.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF4434 PF14488.1 EDN97499.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Ribosomal_S10 PF00338.17 EDN97500.1 - 2.7e-29 100.8 0.3 3.2e-29 100.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.4 EDN97500.1 - 0.029 12.7 0.0 0.029 12.7 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein CUE PF02845.11 EDN97501.1 - 5.2e-09 35.4 0.0 1.3e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain EI24 PF07264.6 EDN97503.1 - 4.2e-08 32.8 5.0 2e-06 27.3 3.5 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3993 PF13158.1 EDN97503.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) FmdA_AmdA PF03069.10 EDN97504.1 - 1.1e-93 313.9 0.6 5.3e-56 189.8 0.0 2.0 2 0 0 2 2 2 2 Acetamidase/Formamidase family CoA_trans PF01144.18 EDN97506.1 - 9.4e-90 299.5 1.0 1e-59 201.3 0.0 3.0 2 1 1 3 3 3 3 Coenzyme A transferase RNase_H PF00075.19 EDN97511.1 - 2.7e-15 56.8 0.0 5.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN97511.1 - 0.0042 17.3 0.2 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc5 PF03221.11 EDN97512.1 - 1.9e-17 62.8 0.0 1.3e-16 60.1 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN97512.1 - 1.3e-16 60.3 0.0 2.1e-09 36.8 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97512.1 - 0.00032 20.1 0.7 0.00084 18.8 0.1 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN97512.1 - 0.0047 16.9 0.1 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3400 PF11880.3 EDN97512.1 - 0.03 13.5 0.1 1.8 7.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3400) UPF0180 PF03698.8 EDN97512.1 - 0.045 13.5 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) HTH_AsnC-type PF13404.1 EDN97512.1 - 0.065 12.7 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rap1-DNA-bind PF09197.5 EDN97512.1 - 0.077 13.5 0.3 0.82 10.2 0.0 2.8 3 0 0 3 3 3 0 Rap1, DNA-binding MarR_2 PF12802.2 EDN97512.1 - 0.1 12.3 0.0 0.37 10.4 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.1 EDN97512.1 - 0.33 11.0 2.9 0.36 11.0 0.1 2.5 3 1 1 4 4 4 0 Winged helix-turn helix DUF4484 PF14831.1 EDN97513.1 - 0.12 12.5 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) SAM_PNT PF02198.11 EDN97515.1 - 0.037 13.7 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DDE_1 PF03184.14 EDN97516.1 - 3.7e-19 68.7 0.1 5.7e-18 64.8 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97516.1 - 2.1e-13 49.5 0.1 4.4e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN97516.1 - 1.1e-11 44.3 0.0 2.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDN97516.1 - 5.7e-05 22.8 0.0 0.0002 21.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN97516.1 - 0.0025 17.5 0.2 0.0059 16.4 0.1 1.6 1 0 0 1 1 1 1 NUMOD1 domain HTH_28 PF13518.1 EDN97516.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EDN97516.1 - 0.0062 15.9 0.4 0.012 14.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.1 EDN97516.1 - 0.0067 16.2 0.7 0.014 15.2 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN97516.1 - 0.0068 16.0 0.1 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_DeoR PF08220.7 EDN97516.1 - 0.051 13.1 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EDN97516.1 - 0.08 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 UPF0175 PF03683.8 EDN97516.1 - 0.082 12.3 0.1 0.26 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) DDE_1 PF03184.14 EDN97517.1 - 5.4e-17 61.6 0.0 1.1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97517.1 - 1.2e-09 37.5 0.0 2.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN97517.1 - 1.8e-06 27.6 0.1 6.1e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.1 EDN97517.1 - 0.013 14.9 0.2 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.1 EDN97517.1 - 0.058 13.2 0.4 0.11 12.3 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN97517.1 - 0.11 12.2 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Pyr_redox PF00070.22 EDN97518.1 - 0.055 13.8 0.1 0.17 12.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RVT_2 PF07727.9 EDN97519.1 - 1.4e-48 164.9 0.0 2.5e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN97519.1 - 2.9e-08 33.8 0.0 8.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN97519.1 - 0.00013 21.5 0.7 0.00036 20.1 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain HTH_Tnp_Tc5 PF03221.11 EDN97520.1 - 3.2e-11 42.8 0.0 5.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDN97520.1 - 0.037 12.9 0.1 0.053 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Pkinase PF00069.20 EDN97521.1 - 9.9e-14 51.1 0.0 4.9e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97521.1 - 5.4e-06 25.6 0.0 6.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_2 PF07992.9 EDN97522.1 - 4e-05 23.5 0.0 0.00038 20.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN97522.1 - 0.00033 20.4 0.0 0.0099 15.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDN97522.1 - 0.00051 20.1 0.0 0.12 12.3 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN97522.1 - 0.0049 15.8 0.2 0.011 14.6 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Aminotran_1_2 PF00155.16 EDN97522.1 - 0.048 12.6 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Malic_M PF03949.10 EDN97522.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DDE_1 PF03184.14 EDN97523.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97523.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97523.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97523.1 - 4.2e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN97523.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle PetL PF05115.9 EDN97524.1 - 0.04 13.8 1.6 0.083 12.8 1.1 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) DUF3431 PF11913.3 EDN97525.1 - 6.7e-34 117.3 0.0 8.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Hydrolase_4 PF12146.3 EDN97526.1 - 0.049 13.4 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 EDN97527.1 - 4.3e-10 39.8 0.0 4.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN97527.1 - 9.7e-05 22.1 0.0 0.00011 22.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN97527.1 - 0.0061 16.1 0.0 0.0071 15.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Colicin_D PF11429.3 EDN97527.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Colicin D TAF1_subA PF14929.1 EDN97528.1 - 0.018 13.5 1.9 0.019 13.4 1.3 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A KAP PF05804.7 EDN97528.1 - 0.048 11.5 0.1 0.05 11.5 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) MIP PF00230.15 EDN97530.1 - 3e-51 174.0 14.1 3.8e-51 173.7 9.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein FAD_binding_3 PF01494.14 EDN97531.1 - 9.1e-21 74.2 0.0 3.4e-20 72.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDN97531.1 - 2.4e-07 30.6 0.2 5.6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN97531.1 - 1.6e-05 23.9 1.4 0.00095 18.1 0.5 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN97531.1 - 8.6e-05 21.5 1.6 0.00031 19.7 0.9 1.9 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDN97531.1 - 0.0006 19.9 0.0 0.00099 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN97531.1 - 0.00083 19.2 0.9 0.0028 17.5 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN97531.1 - 0.0022 18.3 0.0 0.17 12.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN97531.1 - 0.0041 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EDN97531.1 - 0.008 16.0 0.8 0.022 14.6 0.1 2.1 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.12 EDN97531.1 - 0.026 13.6 0.2 0.055 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EDN97531.1 - 0.048 12.1 0.2 0.079 11.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EDN97531.1 - 0.08 12.7 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EDN97531.1 - 0.11 11.3 0.5 0.17 10.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A His_Phos_2 PF00328.17 EDN97532.1 - 9.4e-09 35.0 0.0 4e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) UPF0236 PF06782.6 EDN97533.1 - 0.042 12.2 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) PI-PLC-X PF00388.14 EDN97534.1 - 1.1e-08 34.6 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Eaf7 PF07904.8 EDN97535.1 - 0.15 12.0 0.4 9.1 6.3 0.1 2.1 1 1 1 2 2 2 0 Chromatin modification-related protein EAF7 DDE_1 PF03184.14 EDN97538.1 - 1.7e-52 177.6 0.0 3e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97538.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97538.1 - 1.2e-08 34.8 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97538.1 - 4.2e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN97538.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.13 EDN97539.1 - 1.1e-05 25.1 7.6 2.3e-05 24.1 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN97539.1 - 2.1e-05 23.3 0.0 6.2e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.11 EDN97541.1 - 8.6e-08 31.8 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDN97541.1 - 0.15 10.9 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Abhydrolase_3 PF07859.8 EDN97545.1 - 1.1e-21 77.4 0.0 2.1e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN97545.1 - 4.9e-17 61.6 0.0 6.4e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_2 PF02230.11 EDN97545.1 - 0.0078 15.6 0.0 0.23 10.8 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EDN97547.1 - 1.2e-19 70.2 30.3 3.9e-16 58.7 16.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDN97547.1 - 6e-11 41.2 8.7 9.4e-11 40.6 6.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNase_H PF00075.19 EDN97547.1 - 5.1e-08 33.3 0.1 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN97547.1 - 0.009 16.3 0.1 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PsbL PF02419.12 EDN97547.1 - 9.1 5.8 6.4 6.6 6.2 0.0 2.8 3 0 0 3 3 3 0 PsbL protein Phospholamban PF04272.9 EDN97549.1 - 0.019 14.3 0.9 0.032 13.6 0.6 1.3 1 0 0 1 1 1 0 Phospholamban Totivirus_coat PF05518.6 EDN97551.1 - 1 7.1 6.2 1.2 6.8 4.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein DDE_1 PF03184.14 EDN97552.1 - 9.3e-42 142.6 0.1 1.9e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97552.1 - 2.6e-14 52.7 1.3 6.9e-14 51.4 0.0 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN97552.1 - 1.5e-08 34.0 0.1 2.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97552.1 - 2.4e-07 30.6 0.0 7.2e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDN97552.1 - 0.01 15.6 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 NUMOD1 domain MUG113 PF13455.1 EDN97553.1 - 5.3e-31 106.8 0.5 5.3e-31 106.8 0.4 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EDN97553.1 - 7.4e-22 77.6 2.4 8.3e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 T5orf172 domain CENP-F_leu_zip PF10473.4 EDN97554.1 - 0.042 13.7 33.7 0.68 9.7 0.4 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myc-LZ PF02344.10 EDN97554.1 - 0.069 12.7 11.1 2.1 8.0 2.0 3.9 1 1 2 3 3 3 0 Myc leucine zipper domain ATG16 PF08614.6 EDN97554.1 - 1.5 8.6 23.6 0.67 9.7 0.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4337 PF14235.1 EDN97554.1 - 4.5 7.0 28.1 0.94 9.3 10.7 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) HTH_Tnp_Tc5 PF03221.11 EDN97555.1 - 9.6e-08 31.7 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDN97555.1 - 0.053 12.3 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) zf-CCHC PF00098.18 EDN97555.1 - 0.13 12.2 5.6 0.26 11.2 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN97555.1 - 1.3 8.7 3.8 2.8 7.6 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF904 PF06005.7 EDN97555.1 - 3.5 7.9 5.6 0.59 10.4 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) WD40 PF00400.27 EDN97557.1 - 4.3e-21 73.9 22.1 0.00012 21.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EDN97557.1 - 0.00076 19.2 0.1 0.42 10.2 0.0 3.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.9 EDN97558.1 - 4.7e-66 222.7 5.6 6.2e-62 209.2 1.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EDN97558.1 - 0.012 15.6 3.8 0.012 15.6 2.7 4.0 3 1 1 4 4 4 0 EamA-like transporter family DUF1772 PF08592.6 EDN97558.1 - 3.5 7.3 8.7 1.6 8.4 0.7 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF759 PF05537.6 EDN97559.1 - 0.76 8.4 5.2 0.47 9.1 1.2 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) Sugar_tr PF00083.19 EDN97561.1 - 1.6e-106 356.5 25.3 2.1e-106 356.2 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN97561.1 - 1.6e-26 92.9 30.4 3.2e-18 65.5 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EDN97561.1 - 0.003 17.5 1.2 0.17 11.9 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) OATP PF03137.15 EDN97561.1 - 0.1 10.6 9.1 0.041 11.9 2.5 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S10 PF00450.17 EDN97562.1 - 5.4e-101 338.7 5.1 6.6e-101 338.4 3.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RVT_1 PF00078.22 EDN97563.1 - 4.1e-35 121.0 1.7 7.5e-35 120.2 1.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN97563.1 - 6.2e-15 55.7 0.6 3e-14 53.4 0.1 2.3 2 0 0 2 2 2 1 RNase H DIL PF01843.14 EDN97564.1 - 0.05 13.4 0.1 0.05 13.4 0.1 1.0 1 0 0 1 1 1 0 DIL domain RVT_1 PF00078.22 EDN97565.1 - 6.4e-38 130.2 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN97565.1 - 3.8e-15 55.5 0.5 1.6e-14 53.4 0.2 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN97565.1 - 4.2e-15 56.2 0.0 8.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN97565.1 - 8.4e-05 22.6 0.3 0.00018 21.5 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF993 PF06187.6 EDN97565.1 - 0.13 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Ank_2 PF12796.2 EDN97566.1 - 3.7e-06 27.1 3.0 0.79 10.0 0.2 5.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) AAA_16 PF13191.1 EDN97566.1 - 7.5e-06 26.0 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN97566.1 - 5.5e-05 23.3 0.0 0.00035 20.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN97566.1 - 9.1e-05 22.1 0.0 0.00024 20.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Nitro_FeMo-Co PF02579.12 EDN97566.1 - 0.0093 16.0 14.2 5.3 7.1 0.1 6.8 1 1 8 9 9 9 2 Dinitrogenase iron-molybdenum cofactor DUF676 PF05057.9 EDN97566.1 - 0.022 14.0 0.1 0.2 10.9 0.0 2.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_10 PF12846.2 EDN97566.1 - 0.025 14.0 0.0 0.2 11.0 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EDN97566.1 - 0.067 13.3 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF1269 PF06897.7 EDN97566.1 - 0.09 12.8 5.9 6.3 6.8 0.1 4.6 3 1 0 4 4 4 0 Protein of unknown function (DUF1269) AAA_17 PF13207.1 EDN97566.1 - 0.17 12.7 5.9 0.61 10.9 0.0 4.4 4 1 1 5 5 5 0 AAA domain COX4_pro_2 PF07835.7 EDN97567.1 - 0.043 13.7 2.2 0.052 13.5 0.1 2.2 2 1 1 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV Pkinase PF00069.20 EDN97571.1 - 1.9e-08 33.7 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97571.1 - 0.0004 19.5 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN97571.1 - 0.0043 16.8 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DDE_1 PF03184.14 EDN97572.1 - 1.2e-48 165.1 0.0 2e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN97572.1 - 7.9e-10 38.1 0.5 6.9e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN97572.1 - 1.9e-06 27.7 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN97572.1 - 0.022 14.6 7.0 0.044 13.7 4.9 1.5 1 0 0 1 1 1 0 Zinc knuckle HTH_24 PF13412.1 EDN97572.1 - 0.024 13.9 0.2 0.062 12.6 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.1 EDN97572.1 - 0.066 13.0 0.2 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN97572.1 - 0.16 11.6 0.8 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain RNase_H PF00075.19 EDN97573.1 - 6.3e-11 42.7 0.0 1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN97573.1 - 0.003 17.8 0.1 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ubie_methyltran PF01209.13 EDN97574.1 - 6.4e-07 28.7 0.0 2.9e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDN97574.1 - 1.2e-06 29.0 0.0 8.8e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN97574.1 - 1.9e-06 27.5 0.0 1.8e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN97574.1 - 1.3e-05 25.5 0.0 0.00018 21.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN97574.1 - 2.5e-05 24.5 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN97574.1 - 4.7e-05 23.7 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN97574.1 - 0.00063 19.7 0.0 0.0015 18.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN97574.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EDN97574.1 - 0.0015 18.2 0.0 0.0044 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NAAA-beta PF15508.1 EDN97575.1 - 5.2e-18 65.1 0.0 7.8e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Aldo_ket_red PF00248.16 EDN97576.1 - 8.9e-44 149.3 0.0 1.3e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2480 PF10652.4 EDN97576.1 - 0.077 12.5 0.0 7.1 6.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2480) Neisseria_TspB PF05616.8 EDN97577.1 - 3.1 6.0 10.3 5.5 5.2 7.1 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CLP_protease PF00574.18 EDN97579.1 - 1.7e-74 249.3 0.0 2e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease ECH PF00378.15 EDN97579.1 - 0.065 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Ribosomal_S9 PF00380.14 EDN97579.1 - 0.075 13.2 0.0 0.096 12.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Lge1 PF11488.3 EDN97579.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Hydrolase_4 PF12146.3 EDN97581.1 - 3.9e-18 65.0 0.0 6.8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EDN97581.1 - 1.3e-14 54.6 0.0 1.4e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN97581.1 - 4.6e-13 49.1 0.0 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EDN97581.1 - 0.0077 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EDN97581.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein PAF-AH_p_II PF03403.8 EDN97581.1 - 0.069 11.4 0.0 1.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Methyltransf_31 PF13847.1 EDN97582.1 - 5.1e-06 26.1 0.0 0.00078 19.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain GCD14 PF08704.5 EDN97582.1 - 0.00014 21.4 0.5 0.065 12.7 0.0 2.8 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EDN97582.1 - 0.044 14.3 0.0 15 6.2 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.23 EDN97583.1 - 4.9e-13 48.9 0.2 7.1e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN97583.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TMF_DNA_bd PF12329.3 EDN97587.1 - 0.00086 19.0 3.9 0.078 12.7 0.3 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EDN97587.1 - 0.0021 17.9 3.2 0.0044 16.9 2.2 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 EDN97587.1 - 0.0026 17.4 3.1 0.5 10.1 0.5 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EDN97587.1 - 0.015 15.1 2.6 0.026 14.3 1.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EDN97587.1 - 0.031 13.3 8.4 0.047 12.7 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EDN97587.1 - 0.04 14.2 4.9 0.23 11.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Lge1 PF11488.3 EDN97587.1 - 0.095 12.9 3.8 0.33 11.1 0.3 2.6 2 1 1 3 3 2 0 Transcriptional regulatory protein LGE1 zf-C4H2 PF10146.4 EDN97587.1 - 0.44 10.5 7.5 0.78 9.7 5.2 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Fib_alpha PF08702.5 EDN97587.1 - 0.93 9.6 4.0 2.6 8.1 2.7 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 EDN97587.1 - 1.2 9.1 5.9 12 5.9 0.2 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EDN97587.1 - 4.3 6.9 6.4 51 3.3 4.5 2.0 1 1 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 EDN97587.1 - 4.9 6.9 8.9 6.2 6.6 1.4 2.2 1 1 2 3 3 3 0 Axonemal dynein light chain Bap31 PF05529.7 EDN97587.1 - 9 5.7 6.8 2.3e+02 1.0 4.7 2.2 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Tash_PEST PF07708.6 EDN97588.1 - 0.031 14.1 0.4 0.046 13.6 0.3 1.3 1 0 0 1 1 1 0 Tash protein PEST motif Methyltransf_23 PF13489.1 EDN97589.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN97589.1 - 0.018 15.3 0.2 0.071 13.4 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EDN97589.1 - 0.037 14.0 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EDN97589.1 - 0.043 12.8 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EDN97589.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain PEP-utilisers_N PF05524.8 EDN97590.1 - 0.017 14.9 1.0 0.021 14.6 0.7 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal SR-25 PF10500.4 EDN97590.1 - 0.08 12.3 8.4 0.1 12.0 5.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_11 PF13414.1 EDN97592.1 - 4.5e-14 51.8 0.0 5.8e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN97592.1 - 1.4e-09 37.1 3.1 7.8e-06 25.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN97592.1 - 3e-06 26.5 0.4 0.008 15.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN97592.1 - 2e-05 24.4 0.3 0.0011 18.8 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97592.1 - 6.4e-05 23.2 4.9 0.0027 18.2 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN97592.1 - 0.00019 20.9 0.1 0.0063 16.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN97592.1 - 0.00019 21.7 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN97592.1 - 0.00027 21.5 0.3 0.0018 18.8 0.2 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN97592.1 - 0.0097 15.7 1.2 0.03 14.1 0.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN97592.1 - 0.028 14.2 0.3 23 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN97592.1 - 0.14 12.6 0.1 0.63 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN97592.1 - 0.57 10.1 2.5 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDN97592.1 - 0.98 10.0 8.3 0.55 10.8 1.5 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat E2F_TDP PF02319.15 EDN97593.1 - 0.1 12.1 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain MFS_2 PF13347.1 EDN97594.1 - 6e-09 34.8 17.1 1.2e-07 30.4 11.0 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein Na_H_Exchanger PF00999.16 EDN97595.1 - 1.2e-50 172.2 30.4 1.6e-41 142.0 17.1 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF605 PF04652.11 EDN97595.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Vta1 like PepSY_TM_2 PF13703.1 EDN97595.1 - 7.3 6.8 13.6 0.33 11.1 0.7 4.2 4 1 0 4 4 4 0 PepSY-associated TM helix MFS_1 PF07690.11 EDN97596.1 - 1.8e-19 69.6 41.7 4.3e-19 68.4 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN97596.1 - 3e-06 26.1 7.8 3e-06 26.1 5.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DMPK_coil PF08826.5 EDN97597.1 - 0.0051 16.6 2.4 0.015 15.2 1.1 2.0 2 0 0 2 2 2 1 DMPK coiled coil domain like Tubulin-binding PF00418.14 EDN97597.1 - 0.12 12.0 0.5 0.44 10.2 0.1 2.0 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat RVT_thumb PF06817.9 EDN97599.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain ADIP PF11559.3 EDN97602.1 - 0.0045 16.9 6.5 0.027 14.3 1.4 2.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.6 EDN97602.1 - 0.014 15.2 4.6 0.035 14.0 3.2 1.7 1 1 0 1 1 1 0 Rabaptin-like protein Rho_Binding PF08912.6 EDN97602.1 - 0.025 14.8 3.2 0.025 14.8 2.2 2.0 2 0 0 2 2 1 0 Rho Binding NPV_P10 PF05531.7 EDN97602.1 - 0.059 13.6 1.4 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.3 EDN97602.1 - 0.083 12.1 3.1 0.48 9.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.5 EDN97602.1 - 0.17 11.9 8.0 1.1 9.3 3.3 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil HALZ PF02183.13 EDN97602.1 - 0.23 11.2 7.7 16 5.3 3.2 3.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper Tup_N PF08581.5 EDN97602.1 - 0.26 11.4 6.9 0.13 12.4 1.9 2.6 2 2 1 3 3 3 0 Tup N-terminal DivIC PF04977.10 EDN97602.1 - 0.28 10.6 7.4 11 5.5 0.1 3.7 2 1 0 3 3 3 0 Septum formation initiator Lectin_N PF03954.9 EDN97602.1 - 0.43 9.9 2.9 0.47 9.8 0.5 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 EDN97602.1 - 0.82 9.4 4.7 1.9 8.2 3.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_2 PF07716.10 EDN97602.1 - 1.4 8.7 9.3 6.1 6.7 1.9 3.7 3 1 1 4 4 3 0 Basic region leucine zipper DUF904 PF06005.7 EDN97602.1 - 2.7 8.3 13.1 33 4.8 5.3 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) XhlA PF10779.4 EDN97602.1 - 3.7 7.5 7.2 0.15 11.9 0.3 2.3 3 0 0 3 3 2 0 Haemolysin XhlA Syntaxin PF00804.20 EDN97602.1 - 9.4 6.4 9.4 2.3 8.4 3.3 2.3 2 1 0 2 2 2 0 Syntaxin NHase_beta PF02211.10 EDN97603.1 - 0.031 13.9 0.7 5.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Nitrile hydratase beta subunit His_biosynth PF00977.16 EDN97604.1 - 1.6e-34 119.1 0.0 1.9e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.6 EDN97604.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein PcrB PF01884.12 EDN97604.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PcrB family DUF4602 PF15375.1 EDN97605.1 - 4e-05 23.7 14.5 0.00012 22.2 10.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) CAF1 PF04857.15 EDN97606.1 - 2.2e-55 187.8 0.0 3e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EDN97607.1 - 1.9e-21 75.5 0.1 2.9e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Response_reg PF00072.19 EDN97608.1 - 1.6e-18 66.6 0.4 8.8e-15 54.6 0.2 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EDN97608.1 - 4.6e-16 58.5 0.1 9.2e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF89 PF01937.14 EDN97609.1 - 6.9e-135 449.4 0.0 7.9e-135 449.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Acetyltransf_3 PF13302.1 EDN97610.1 - 2.2e-06 27.8 0.0 6.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN97610.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDN97610.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDN97610.1 - 0.016 15.3 0.1 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M26_C PF07580.9 EDN97610.1 - 0.065 11.5 0.1 0.093 11.0 0.1 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region DUF2946 PF11162.3 EDN97611.1 - 0.055 13.6 0.9 0.12 12.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) BAF1_ABF1 PF04684.8 EDN97611.1 - 0.2 10.4 8.8 0.41 9.4 6.1 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 EDN97611.1 - 0.26 10.6 0.1 0.26 10.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 EDN97611.1 - 0.29 11.1 0.8 0.72 9.9 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3328 PF11807.3 EDN97612.1 - 1.4e-24 86.9 2.9 2.5e-24 86.1 2.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EDN97613.1 - 2.1e-53 181.2 1.3 2.8e-53 180.8 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) XPG_I PF00867.13 EDN97615.1 - 0.063 13.3 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 XPG I-region C2-set_2 PF08205.7 EDN97615.1 - 0.14 12.0 1.2 39 4.2 0.0 3.0 1 1 2 3 3 3 0 CD80-like C2-set immunoglobulin domain HTH_psq PF05225.11 EDN97618.1 - 1.6e-05 24.3 0.9 2.6e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDN97618.1 - 0.00073 18.7 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Chitin_synth_2 PF03142.10 EDN97618.1 - 0.0082 14.5 0.0 0.0082 14.5 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase DUF1295 PF06966.7 EDN97619.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Ribosomal_S7e PF01251.13 EDN97623.1 - 7.9e-84 279.8 0.1 8.9e-84 279.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Glyco_transf_41 PF13844.1 EDN97624.1 - 3.3e-97 325.3 0.1 1.5e-49 168.2 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EDN97624.1 - 1.7e-21 75.6 6.1 1.3e-06 27.9 0.0 4.9 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EDN97624.1 - 2.9e-18 64.6 5.7 4.6e-05 22.8 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDN97624.1 - 5.9e-17 60.1 7.5 0.0035 17.1 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN97624.1 - 8.7e-16 57.6 2.1 3.8e-07 29.9 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN97624.1 - 5.9e-12 44.7 1.4 0.096 12.9 0.0 5.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN97624.1 - 1.5e-10 41.4 5.1 0.015 15.9 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN97624.1 - 7.3e-10 37.9 5.6 0.007 16.0 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97624.1 - 1.7e-09 37.4 6.1 0.0027 18.1 0.0 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN97624.1 - 1.8e-09 36.6 1.4 0.0014 18.2 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDN97624.1 - 3e-08 33.3 5.6 0.35 10.8 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDN97624.1 - 4.6e-07 30.0 1.3 0.034 14.4 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN97624.1 - 2.4e-05 24.4 1.3 1.4 9.5 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN97624.1 - 0.0044 17.1 0.1 2.1 8.5 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN97624.1 - 0.029 14.2 2.2 0.53 10.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 EDN97624.1 - 0.053 13.5 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat Ribosomal_L11_N PF03946.9 EDN97625.1 - 7.6e-18 63.7 0.0 1.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDN97625.1 - 1.2e-11 44.5 0.4 1.9e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EDN97625.1 - 0.0019 17.8 0.4 0.074 12.7 0.0 2.6 1 1 1 2 2 2 2 Translation initiation factor IF-2, N-terminal region Sec23_trunk PF04811.10 EDN97626.1 - 2e-80 269.6 0.0 2.8e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN97626.1 - 1.6e-34 117.3 0.8 3.8e-34 116.2 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDN97626.1 - 1.4e-30 105.6 0.2 2.9e-30 104.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDN97626.1 - 3.1e-16 58.6 6.6 6.2e-16 57.6 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDN97626.1 - 7.7e-13 47.9 0.0 2.3e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat HsbA PF12296.3 EDN97627.1 - 1.3e-25 89.6 0.0 2.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Drf_FH1 PF06346.7 EDN97627.1 - 0.016 14.6 3.6 0.029 13.8 2.5 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 FAD-SLDH PF12318.3 EDN97627.1 - 0.031 13.9 0.3 0.058 13.0 0.2 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase NIT PF08376.5 EDN97627.1 - 0.044 13.3 1.2 0.065 12.7 0.2 1.6 2 0 0 2 2 2 0 Nitrate and nitrite sensing DUF842 PF05811.8 EDN97627.1 - 0.068 12.6 0.3 0.068 12.6 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cytadhesin_P30 PF07271.6 EDN97627.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF883 PF05957.8 EDN97627.1 - 0.9 9.9 3.3 1.2 9.5 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Fibrillarin PF01269.12 EDN97629.1 - 1.1e-106 354.9 0.0 1.3e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EDN97629.1 - 8.8e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EDN97629.1 - 0.0043 16.6 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EDN97629.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Dynactin_p62 PF05502.8 EDN97630.1 - 4.7e-123 411.4 0.0 6.5e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Myb_DNA-binding PF00249.26 EDN97634.1 - 5.6e-23 80.7 0.3 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN97634.1 - 2.3e-18 66.0 0.3 5.9e-13 48.7 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EDN97634.1 - 0.049 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) DUF3463 PF11946.3 EDN97638.1 - 0.077 12.5 0.3 0.087 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Ureidogly_hydro PF04115.7 EDN97639.1 - 4.2e-55 185.5 0.0 5.4e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Myb_DNA-bind_4 PF13837.1 EDN97640.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN97640.1 - 0.097 12.7 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain ELO PF01151.13 EDN97641.1 - 3.5e-85 285.2 10.1 4.6e-85 284.8 7.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2414 PF10309.4 EDN97643.1 - 8e-24 83.0 0.0 1.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Cas1_AcylT PF07779.7 EDN97644.1 - 1.9e-108 363.0 24.2 2.3e-107 359.4 16.7 2.3 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EDN97644.1 - 3e-38 132.1 0.1 4.9e-38 131.4 0.1 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_S10 PF00450.17 EDN97645.1 - 3.3e-86 290.0 8.9 3.2e-85 286.7 6.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Inhibitor_I36 PF03995.8 EDN97645.1 - 0.31 11.4 4.2 23 5.4 0.0 3.6 4 0 0 4 4 4 0 Peptidase inhibitor family I36 Peptidase_S10 PF00450.17 EDN97646.1 - 1.2e-131 439.6 1.1 1.8e-131 439.1 0.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EDN97646.1 - 2.8e-10 40.3 0.6 5.2e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EDN97646.1 - 0.00038 20.4 0.1 0.0031 17.4 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family SBDS_C PF09377.5 EDN97647.1 - 1.5e-37 128.0 0.5 2.5e-37 127.3 0.3 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EDN97647.1 - 5.3e-30 103.0 0.1 1.2e-29 101.9 0.1 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.17 EDN97648.1 - 1e-40 138.4 1.2 1.2e-40 138.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDN97648.1 - 0.0055 15.3 0.0 0.0056 15.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EDN97648.1 - 0.1 12.6 0.5 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Ribosomal_L22 PF00237.14 EDN97649.1 - 1.5e-34 118.1 0.0 2.1e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4506 PF14958.1 EDN97649.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) GMC_oxred_N PF00732.14 EDN97654.1 - 1.7e-47 162.0 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN97654.1 - 4.4e-15 56.2 0.0 7.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDN97654.1 - 7.5e-08 31.6 0.0 2.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN97654.1 - 0.00019 21.4 0.3 0.00057 19.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN97654.1 - 0.0017 17.3 0.1 0.0033 16.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EDN97654.1 - 0.0026 18.1 0.1 0.59 10.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN97654.1 - 0.0069 15.2 0.1 0.1 11.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDN97654.1 - 0.088 12.8 0.0 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LysM PF01476.15 EDN97655.1 - 2.4e-08 33.7 0.0 0.12 12.3 0.0 3.5 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.23 EDN97656.1 - 2.1e-70 237.9 0.8 3e-70 237.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EDN97656.1 - 1.3e-08 34.6 6.8 1.3e-08 34.6 4.7 4.4 5 0 0 5 5 5 1 Chitin recognition protein Glyco_hydro_85 PF03644.8 EDN97656.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DDE_1 PF03184.14 EDN97658.1 - 1.5e-13 50.3 0.8 8.9e-11 41.3 0.0 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97658.1 - 1.7e-11 43.7 0.0 3.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN97658.1 - 0.0017 18.0 0.5 0.0073 16.0 0.1 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF3608 PF12257.3 EDN97658.1 - 0.027 13.3 0.3 0.041 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) DUF2701 PF10857.3 EDN97658.1 - 0.14 11.9 0.1 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) LysM PF01476.15 EDN97659.1 - 3.1e-09 36.5 0.0 0.03 14.2 0.0 4.4 4 0 0 4 4 4 4 LysM domain DUF4087 PF13316.1 EDN97659.1 - 1.6 8.9 7.1 2.5 8.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4087) FA_hydroxylase PF04116.8 EDN97667.1 - 1.8e-17 63.7 8.8 1.8e-17 63.7 6.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 EDN97668.1 - 1.3e-22 80.5 2.5 1.5e-22 80.3 1.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Peptidase_S64 PF08192.6 EDN97669.1 - 3.6 5.7 4.1 5.1 5.3 2.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mtc PF03820.12 EDN97672.1 - 1.2e-72 244.1 3.4 3.7e-60 203.1 1.0 2.9 1 1 1 2 2 2 2 Tricarboxylate carrier Pkinase PF00069.20 EDN97673.1 - 3.6e-60 203.3 0.1 6.1e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97673.1 - 5.9e-21 74.6 0.1 1.5e-19 70.0 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Lactamase_B_2 PF12706.2 EDN97674.1 - 6.1e-32 110.7 0.3 1e-31 110.0 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EDN97674.1 - 5.7e-25 86.5 0.1 2.1e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EDN97674.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pex14_N PF04695.8 EDN97676.1 - 0.033 14.2 0.1 0.033 14.2 0.1 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FCP1_C PF09309.5 EDN97676.1 - 0.093 12.0 11.2 0.12 11.6 7.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal NESP55 PF06390.7 EDN97676.1 - 0.33 10.2 11.9 0.42 9.9 8.2 1.3 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 EDN97676.1 - 1.3 8.8 13.7 2.1 8.1 8.6 1.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.8 EDN97676.1 - 1.8 6.2 7.4 2.5 5.7 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.6 EDN97676.1 - 2.1 7.8 8.4 2.8 7.4 5.8 1.1 1 0 0 1 1 1 0 PPP4R2 DUF1146 PF06612.6 EDN97677.1 - 0.05 13.5 0.4 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) Fungal_trans PF04082.13 EDN97678.1 - 1e-27 96.6 0.0 1.9e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN97678.1 - 1.4e-09 37.6 11.5 2.3e-09 37.0 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3881 PF12997.2 EDN97678.1 - 0.062 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) adh_short_C2 PF13561.1 EDN97680.1 - 1.1e-18 67.9 0.2 7.7e-16 58.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN97680.1 - 7.1e-14 52.0 3.0 3.1e-08 33.6 0.4 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EDN97680.1 - 7.9e-07 28.9 0.4 2e-06 27.5 0.1 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EDN97680.1 - 0.0015 17.9 0.3 0.029 13.7 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YbbR PF07949.7 EDN97681.1 - 0.14 12.2 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 YbbR-like protein DUF2235 PF09994.4 EDN97682.1 - 1.8e-72 244.0 0.0 2.1e-71 240.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EDN97682.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family N2227 PF07942.7 EDN97683.1 - 1.2e-94 316.3 0.0 1.4e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EDN97683.1 - 2.1e-08 34.0 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN97683.1 - 2.9e-05 24.4 0.0 0.00036 20.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN97683.1 - 0.0009 19.6 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN97683.1 - 0.01 16.3 0.0 0.028 14.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EDN97683.1 - 0.096 12.2 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PAP_central PF04928.12 EDN97684.1 - 3.7e-109 363.4 0.0 4.8e-109 363.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EDN97684.1 - 1.6e-49 167.4 0.0 2.6e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDN97684.1 - 7.9e-10 38.9 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1186 PF06685.6 EDN97684.1 - 0.15 11.1 0.1 16 4.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1186) DUF2183 PF09949.4 EDN97685.1 - 4.3e-33 113.2 0.0 1.4e-32 111.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DEAD PF00270.24 EDN97686.1 - 4.3e-42 143.4 0.0 1.3e-41 141.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN97686.1 - 6.6e-26 89.9 0.0 1.4e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDN97686.1 - 0.00013 20.5 0.1 0.0021 16.5 0.0 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1253) Acetyltransf_4 PF13420.1 EDN97687.1 - 0.068 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN97687.1 - 0.068 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EDN97688.1 - 2.9e-44 150.3 0.1 3.6e-44 150.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EDN97688.1 - 6.7e-08 33.0 0.0 8.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN97688.1 - 5.6e-07 29.5 0.0 1.2e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDN97688.1 - 3.5e-06 26.3 0.0 3.9e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EDN97688.1 - 1.4e-05 24.5 0.0 1.8e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDN97688.1 - 4.7e-05 22.2 0.1 0.00048 18.9 0.0 2.2 1 1 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.5 EDN97688.1 - 0.00024 20.3 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EDN97688.1 - 0.0024 17.3 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDN97688.1 - 0.01 15.6 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EDN97688.1 - 0.036 13.7 0.3 0.15 11.7 0.2 1.9 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EDN97688.1 - 0.093 12.8 0.1 0.47 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF4045 PF13254.1 EDN97689.1 - 1.9e-79 267.9 43.1 3.1e-45 155.2 18.6 6.5 3 3 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EDN97689.1 - 1.5e-07 30.9 0.0 0.0068 16.0 0.0 3.1 3 0 0 3 3 3 2 Gelsolin repeat TarH PF02203.10 EDN97690.1 - 0.14 11.9 0.1 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Rubredoxin PF00301.15 EDN97692.1 - 0.087 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Rubredoxin DUF2347 PF09804.4 EDN97694.1 - 2.2e-71 240.4 0.0 1.6e-46 158.8 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EDN97694.1 - 7.5e-63 211.7 0.0 1.1e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) CDC48_N PF02359.13 EDN97694.1 - 0.18 11.7 0.0 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Sec63 PF02889.11 EDN97695.1 - 1.1e-47 162.7 0.0 1.1e-45 156.2 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EDN97695.1 - 8.9e-17 60.5 1.9 8.9e-17 60.5 1.3 2.0 2 0 0 2 2 2 1 DnaJ domain TctB PF07331.6 EDN97695.1 - 0.03 13.9 0.2 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family 7tm_1 PF00001.16 EDN97695.1 - 0.19 10.8 0.0 1 8.4 0.0 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SNF2_N PF00176.18 EDN97696.1 - 8.4e-65 218.5 0.0 1.2e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN97696.1 - 2.2e-11 43.4 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN97696.1 - 9.2e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BP28CT PF08146.7 EDN97697.1 - 2e-43 147.7 1.0 2e-43 147.7 0.7 4.3 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EDN97697.1 - 5e-30 103.9 0.1 5e-30 103.9 0.0 4.6 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EDN97697.1 - 2.8e-08 33.1 1.5 0.0071 16.3 0.0 5.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EDN97697.1 - 8.9e-07 29.1 11.3 0.35 11.1 0.1 7.0 6 2 0 6 6 6 3 HEAT repeats NRDE-2 PF08424.5 EDN97698.1 - 1.3e-102 343.0 0.4 1.3e-102 343.0 0.2 3.8 4 0 0 4 4 4 3 NRDE-2, necessary for RNA interference Metallophos PF00149.23 EDN97699.1 - 1.7e-27 96.1 0.0 1.7e-16 60.1 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase HTH_psq PF05225.11 EDN97701.1 - 2e-09 36.8 0.1 4e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN97701.1 - 5.7e-06 26.0 0.0 1.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EDN97701.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein D GST_N_3 PF13417.1 EDN97702.1 - 2.9e-09 37.0 0.1 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN97702.1 - 5.6e-06 26.2 0.1 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN97702.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RPN7 PF10602.4 EDN97703.1 - 8.2e-54 181.6 0.0 1.8e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDN97703.1 - 0.0021 18.3 2.5 0.011 15.9 0.1 2.8 2 1 1 3 3 3 1 PCI domain TPR_2 PF07719.12 EDN97703.1 - 0.053 13.4 0.4 7.3 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_2 PF07724.9 EDN97704.1 - 2.4e-46 157.7 0.0 3.5e-45 153.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDN97704.1 - 1e-27 96.9 0.5 2.1e-14 53.8 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDN97704.1 - 2.6e-23 81.7 0.1 8.8e-23 80.0 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EDN97704.1 - 9.6e-17 61.5 10.9 3e-06 27.3 0.0 6.0 3 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 EDN97704.1 - 1.5e-15 57.1 0.0 1.2e-09 37.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN97704.1 - 8.2e-14 51.8 0.9 5.2e-05 23.4 0.0 4.3 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EDN97704.1 - 2.7e-09 36.7 0.0 2.6e-06 26.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Clp_N PF02861.15 EDN97704.1 - 1.7e-08 34.2 1.7 0.0015 18.4 0.0 4.1 3 0 0 3 3 3 2 Clp amino terminal domain AAA_17 PF13207.1 EDN97704.1 - 1.3e-07 32.4 6.5 0.011 16.4 0.7 3.9 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDN97704.1 - 5.3e-07 29.9 0.1 0.012 15.8 0.0 3.4 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EDN97704.1 - 7.3e-07 28.7 0.0 0.032 13.6 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDN97704.1 - 2.1e-06 27.3 1.2 0.032 13.9 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EDN97704.1 - 9.8e-06 24.8 0.1 0.069 12.3 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EDN97704.1 - 2.5e-05 23.3 0.0 0.0031 16.4 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 EDN97704.1 - 2.8e-05 24.1 0.4 0.27 11.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EDN97704.1 - 3e-05 23.9 0.0 0.19 11.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDN97704.1 - 5.2e-05 23.3 0.0 0.44 10.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 EDN97704.1 - 8.2e-05 21.7 0.2 0.014 14.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin MobB PF03205.9 EDN97704.1 - 0.00016 21.4 0.0 0.64 9.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EDN97704.1 - 0.0002 20.9 0.0 0.98 9.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDN97704.1 - 0.00032 21.0 0.4 0.4 10.9 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 EDN97704.1 - 0.00047 19.6 0.8 1.3 8.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EDN97704.1 - 0.00059 19.6 9.9 0.0088 15.7 0.1 4.5 4 2 0 5 5 3 1 Archaeal ATPase AAA_24 PF13479.1 EDN97704.1 - 0.0008 19.0 0.0 0.81 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDN97704.1 - 0.00094 18.3 0.0 0.4 9.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN97704.1 - 0.00099 18.6 6.7 0.72 9.2 0.1 5.4 5 1 0 5 5 5 1 AAA-like domain AAA_29 PF13555.1 EDN97704.1 - 0.0012 18.3 0.0 0.82 9.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EDN97704.1 - 0.0022 17.8 0.0 0.78 9.5 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EDN97704.1 - 0.0027 17.3 0.0 0.38 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EDN97704.1 - 0.0045 16.4 0.1 4 6.8 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EDN97704.1 - 0.012 15.2 0.0 0.28 10.8 0.0 2.7 2 0 0 2 2 2 0 NTPase Torsin PF06309.6 EDN97704.1 - 0.013 15.4 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_21 PF13304.1 EDN97704.1 - 0.017 15.0 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EDN97704.1 - 0.026 14.1 0.0 8.7 6.0 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EDN97704.1 - 0.031 14.2 0.1 1.5 8.7 0.0 3.7 4 1 0 4 4 3 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EDN97704.1 - 0.035 14.4 6.9 1.3 9.3 0.0 3.9 5 0 0 5 5 3 0 AAA domain PduV-EutP PF10662.4 EDN97704.1 - 0.065 12.7 0.0 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EDN97704.1 - 0.068 12.7 0.0 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Occludin_ELL PF07303.8 EDN97704.1 - 0.51 11.1 5.2 2.1 9.1 3.6 2.1 1 0 0 1 1 1 0 Occludin homology domain Rabaptin PF03528.10 EDN97704.1 - 2.2 8.2 12.9 2.6 8.0 0.2 2.8 2 0 0 2 2 2 0 Rabaptin Cep57_CLD_2 PF14197.1 EDN97704.1 - 9.8 6.2 17.2 1.6 8.7 8.5 2.3 2 1 1 3 3 1 0 Centrosome localisation domain of PPC89 Mhr1 PF12829.2 EDN97705.1 - 3.4e-32 110.1 0.0 3.4e-32 110.1 0.0 2.5 3 0 0 3 3 3 1 Transcriptional regulation of mitochondrial recombination HMG_box_5 PF14887.1 EDN97705.1 - 1.4 8.7 9.5 0.19 11.5 2.7 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 BAF1_ABF1 PF04684.8 EDN97706.1 - 0.28 10.0 3.5 0.44 9.3 2.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fungal_trans PF04082.13 EDN97707.1 - 8.6e-26 90.3 0.2 1.4e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAS_9 PF13426.1 EDN97709.1 - 2.5e-10 40.6 0.0 4.8e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain PSD1 PF07587.6 EDN97709.1 - 0.035 13.4 0.2 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) DUF3431 PF11913.3 EDN97710.1 - 7.6e-86 287.1 1.1 1.2e-85 286.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) IPPT PF01715.12 EDN97710.1 - 0.054 12.4 0.1 0.097 11.6 0.1 1.3 1 0 0 1 1 1 0 IPP transferase Glyco_transf_11 PF01531.11 EDN97710.1 - 0.057 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Rdx PF10262.4 EDN97712.1 - 1.2e-15 57.2 0.2 3.1e-15 55.9 0.1 1.7 1 1 0 1 1 1 1 Rdx family SAGA-Tad1 PF12767.2 EDN97712.1 - 0.028 14.0 1.8 0.038 13.6 1.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit G-gamma PF00631.17 EDN97713.1 - 4.5e-25 87.1 0.0 5.5e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 EDN97714.1 - 3.2e-08 33.8 0.5 1.2e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain CAF-1_p150 PF11600.3 EDN97714.1 - 0.00016 21.1 27.1 0.00016 21.1 18.8 4.0 3 1 0 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal LRR_4 PF12799.2 EDN97718.1 - 8.9e-16 57.1 10.6 1e-05 25.0 4.1 4.2 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN97718.1 - 3.4e-12 45.9 6.3 3.1e-08 33.2 2.7 2.9 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EDN97718.1 - 3.2e-09 35.5 9.3 2.6 8.4 0.2 6.7 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EDN97718.1 - 2e-06 27.2 4.8 1.7 8.9 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 EDN97718.1 - 0.00053 19.7 6.4 19 6.0 0.2 6.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_9 PF14580.1 EDN97718.1 - 0.12 11.8 1.2 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat Cas_Cas02710 PF09670.5 EDN97719.1 - 0.059 11.9 0.0 0.059 11.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Biotin_lipoyl PF00364.17 EDN97722.1 - 2.1e-16 59.2 1.5 4.7e-16 58.1 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EDN97722.1 - 2.1e-06 27.2 0.0 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like E3_binding PF02817.12 EDN97722.1 - 0.0012 18.4 0.0 0.0096 15.5 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain HlyD PF00529.15 EDN97722.1 - 0.0072 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 EDN97722.1 - 0.12 11.5 0.1 1 8.4 0.0 2.1 1 1 0 1 1 1 0 HlyD family secretion protein QRPTase_N PF02749.11 EDN97722.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain YlbE PF14003.1 EDN97727.1 - 0.24 11.5 1.6 0.55 10.3 0.7 1.8 1 1 1 2 2 2 0 YlbE-like protein zf-C4H2 PF10146.4 EDN97729.1 - 3.1 7.7 17.2 0.45 10.4 2.6 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein NAD_binding_6 PF08030.7 EDN97730.1 - 4.4e-05 23.4 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EDN97730.1 - 0.0011 19.5 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PetL PF05115.9 EDN97731.1 - 0.097 12.5 0.5 0.23 11.3 0.4 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Mss4 PF04421.8 EDN97731.1 - 0.13 12.1 0.3 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Mss4 protein DNA_primase_lrg PF04104.9 EDN97734.1 - 4e-81 272.0 0.0 5.3e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Glyco_hydro_12 PF01670.11 EDN97737.1 - 0.033 13.9 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 PDEase_I PF00233.14 EDN97740.1 - 7.6e-46 156.7 0.0 1.3e-42 146.2 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M28 PF04389.12 EDN97742.1 - 1.5e-34 119.2 0.3 3.1e-34 118.2 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDN97742.1 - 0.00016 21.2 0.2 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Exo_endo_phos PF03372.18 EDN97744.1 - 6.4e-21 75.4 0.6 1.2e-20 74.4 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EDN97744.1 - 1.3e-12 47.0 0.5 8.5e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN97744.1 - 3e-10 39.6 4.3 6.9e-06 25.7 0.9 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EDN97744.1 - 1.1e-07 30.8 2.6 0.12 12.4 0.0 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EDN97744.1 - 6.4e-06 25.5 5.2 2.3 8.7 0.3 4.0 3 0 0 3 3 3 3 Leucine rich repeat Methyltransf_25 PF13649.1 EDN97745.1 - 4.8e-10 39.6 0.0 8.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN97745.1 - 8.7e-09 35.7 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN97745.1 - 9.2e-08 32.1 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN97745.1 - 9.8e-08 31.8 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN97745.1 - 1.8e-05 23.9 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDN97745.1 - 2.3e-05 24.9 0.0 6.1e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN97745.1 - 0.00033 20.2 0.0 0.0009 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN97745.1 - 0.00037 20.9 0.0 0.00082 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDN97745.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Complex1_LYR_2 PF13233.1 EDN97746.1 - 1.8e-06 28.3 0.0 2.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN97746.1 - 8.6e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN97746.1 - 1.9e-05 24.8 0.1 2.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.1 EDN97747.1 - 4.9e-23 81.8 0.1 7.4e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EDN97747.1 - 0.0079 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EDN97747.1 - 0.017 14.0 0.1 0.036 12.9 0.1 1.5 1 0 0 1 1 1 0 Acyl-ACP thioesterase DUF4444 PF14563.1 EDN97747.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Selenoprotein_S PF06936.6 EDN97747.1 - 0.11 12.0 0.6 0.17 11.3 0.4 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) HTH_psq PF05225.11 EDN97748.1 - 2e-09 36.8 0.1 3.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDN97748.1 - 1.6e-07 30.6 0.0 4.6e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDN97748.1 - 0.016 14.9 0.3 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 NUMOD1 domain HTH_3 PF01381.17 EDN97748.1 - 0.037 13.8 0.2 0.081 12.7 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.1 EDN97748.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EDN97749.1 - 2.5e-51 174.6 0.0 4.6e-50 170.4 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.17 EDN97751.1 - 3.4e-48 164.2 23.6 3.4e-48 164.2 16.3 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EDN97751.1 - 9.8e-10 38.8 2.8 1.9e-09 37.9 1.9 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Tetraspannin PF00335.15 EDN97754.1 - 0.00072 18.8 2.0 0.00091 18.5 0.8 1.6 1 1 0 1 1 1 1 Tetraspanin family CRPA PF05745.6 EDN97754.1 - 0.11 12.3 3.4 0.76 9.5 0.7 2.2 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) TctB PF07331.6 EDN97754.1 - 1 8.9 8.0 1.2 8.7 2.4 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Peroxidase_2 PF01328.12 EDN97755.1 - 1.1e-33 116.2 0.1 1.4e-33 115.9 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 MIF PF01187.13 EDN97761.1 - 2.5e-09 37.2 0.0 6.2e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.7 EDN97763.1 - 6.4e-74 247.9 0.2 8.6e-74 247.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN97763.1 - 7.4e-06 26.4 0.0 0.00012 22.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN97763.1 - 0.002 17.4 0.0 0.004 16.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN97763.1 - 0.036 13.2 0.0 0.078 12.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PIG-X PF08320.7 EDN97764.1 - 2.4e-70 236.0 0.0 1e-69 233.9 0.0 1.8 2 0 0 2 2 2 1 PIG-X / PBN1 DUF1183 PF06682.7 EDN97765.1 - 9.4e-101 337.5 6.8 1.1e-100 337.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) P12 PF12669.2 EDN97765.1 - 0.0075 16.4 2.5 0.78 9.9 0.2 2.5 2 0 0 2 2 2 2 Virus attachment protein p12 family BRE1 PF08647.6 EDN97766.1 - 2.2e-27 94.8 9.8 2.2e-27 94.8 6.8 7.0 4 2 3 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EDN97766.1 - 8.4e-09 34.9 7.2 1.4e-08 34.2 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN97766.1 - 1.1e-07 31.7 9.3 1.9e-07 30.9 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN97766.1 - 2e-07 30.5 9.7 3.8e-07 29.6 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN97766.1 - 7.7e-06 25.5 9.8 1.3e-05 24.7 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN97766.1 - 9.6e-06 25.3 7.2 1.7e-05 24.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EDN97766.1 - 4.7e-05 23.0 4.9 0.00014 21.5 3.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EDN97766.1 - 0.00026 20.4 3.2 0.00055 19.4 2.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EDN97766.1 - 0.00077 19.2 1.6 0.0015 18.2 1.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EDN97766.1 - 0.0039 17.0 6.6 0.0081 16.0 4.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDN97766.1 - 0.036 13.6 7.3 0.13 11.8 5.2 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 EDN97766.1 - 0.57 9.3 26.9 0.65 9.1 1.5 3.9 1 1 1 4 4 4 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EDN97766.1 - 0.97 7.0 76.1 0.86 7.2 19.0 4.1 2 1 1 3 3 3 0 Myosin tail FYVE PF01363.16 EDN97766.1 - 1 9.2 10.7 1 9.2 3.3 2.5 1 1 1 2 2 2 0 FYVE zinc finger DUF869 PF05911.6 EDN97766.1 - 1.4 7.0 62.9 0.16 10.1 15.5 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Filament PF00038.16 EDN97766.1 - 2.3 7.5 64.6 0.04 13.3 9.8 4.2 2 1 2 4 4 4 0 Intermediate filament protein zf-C2H2_4 PF13894.1 EDN97766.1 - 2.5 8.6 4.5 9.7 6.7 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_1 PF00232.13 EDN97768.1 - 1.1e-160 534.8 0.0 1.3e-160 534.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFA PF04828.9 EDN97769.1 - 0.00018 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EDN97769.1 - 0.93 8.7 3.4 0.31 10.2 0.4 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Apo-CIII PF05778.7 EDN97771.1 - 0.017 14.5 0.1 0.045 13.1 0.1 1.8 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) AAA_13 PF13166.1 EDN97771.1 - 0.19 10.1 20.8 1 7.7 14.5 1.8 1 1 0 1 1 1 0 AAA domain RasGAP_C PF03836.10 EDN97771.1 - 0.21 11.2 22.2 1.3 8.7 9.0 2.6 2 1 0 2 2 2 0 RasGAP C-terminus DUF2353 PF09789.4 EDN97771.1 - 0.28 10.3 28.9 0.69 9.1 13.7 2.5 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Baculo_PEP_C PF04513.7 EDN97771.1 - 0.52 10.1 5.2 2 8.2 3.3 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDN97771.1 - 0.57 9.9 13.2 9.2 6.0 0.1 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-Q PF13094.1 EDN97771.1 - 1.2 9.1 25.8 3 7.8 7.3 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Myb_DNA-bind_4 PF13837.1 EDN97771.1 - 3.2 7.9 17.6 0.4 10.8 1.1 3.4 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain ERM PF00769.14 EDN97771.1 - 4.4 6.7 30.8 0.42 10.0 3.2 2.4 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 EDN97771.1 - 4.6 7.3 19.6 4.7 7.3 1.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EDN97771.1 - 5 6.9 31.5 0.11 12.3 2.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EDN97771.1 - 5.4 5.9 29.4 8.7 5.2 7.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EDN97771.1 - 7 7.1 17.6 1.9 8.9 2.8 3.4 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DUF2527 PF10736.4 EDN97775.1 - 0.29 10.7 1.8 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Apc4_WD40 PF12894.2 EDN97777.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Mnd1 PF03962.10 EDN97779.1 - 0.036 13.7 5.7 0.064 12.9 3.9 1.3 1 0 0 1 1 1 0 Mnd1 family Methyltransf_25 PF13649.1 EDN97779.1 - 0.049 14.0 0.6 2.1 8.7 0.0 2.4 1 1 0 2 2 2 0 Methyltransferase domain DUF896 PF05979.7 EDN97779.1 - 0.057 13.0 1.6 0.15 11.7 1.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) IncA PF04156.9 EDN97779.1 - 0.13 11.8 5.6 0.2 11.2 3.9 1.3 1 0 0 1 1 1 0 IncA protein CHD5 PF04420.9 EDN97779.1 - 0.14 11.8 2.2 0.21 11.2 1.6 1.2 1 0 0 1 1 1 0 CHD5-like protein Atg14 PF10186.4 EDN97779.1 - 2.2 7.1 5.8 3.3 6.5 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EDN97780.1 - 0.32 10.9 2.1 1.5 8.8 0.3 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF148 PF02520.12 EDN97780.1 - 0.36 10.6 13.4 0.63 9.8 0.6 3.7 4 1 0 4 4 4 0 Domain of unknown function DUF148 Fzo_mitofusin PF04799.8 EDN97780.1 - 0.41 10.0 2.9 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 fzo-like conserved region Syntaxin-6_N PF09177.6 EDN97780.1 - 0.56 10.6 11.0 0.39 11.1 0.5 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal WXG100 PF06013.7 EDN97780.1 - 1.6 8.7 6.5 87 3.2 0.0 4.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Aurora-A_bind PF09041.5 EDN97782.1 - 0.43 10.3 3.6 7.6 6.3 0.3 3.8 3 1 0 3 3 3 0 Aurora-A binding DegT_DnrJ_EryC1 PF01041.12 EDN97784.1 - 0.044 12.8 0.4 0.064 12.2 0.3 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1313 PF07011.6 EDN97784.1 - 0.26 10.9 4.8 1.9 8.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1313) DUF2935 PF11155.3 EDN97784.1 - 9.3 6.3 10.2 9.2 6.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) AAA PF00004.24 EDN97785.1 - 4.2e-51 172.5 0.0 1.8e-41 141.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EDN97785.1 - 4.7e-06 26.1 0.0 2.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EDN97785.1 - 1.8e-05 24.7 0.0 6.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN97785.1 - 3.2e-05 24.0 0.1 0.00017 21.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EDN97785.1 - 0.0001 22.0 0.0 0.00037 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN97785.1 - 0.00012 22.2 0.1 0.0062 16.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN97785.1 - 0.00064 19.4 0.3 0.0073 16.0 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EDN97785.1 - 0.0012 18.2 0.0 0.0047 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN97785.1 - 0.0023 17.8 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN97785.1 - 0.0081 16.9 2.4 0.025 15.4 0.0 3.2 4 0 0 4 4 1 1 AAA domain AAA_28 PF13521.1 EDN97785.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EDN97785.1 - 0.0085 16.1 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EDN97785.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN97785.1 - 0.017 15.3 0.0 0.054 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 EDN97785.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 EDN97785.1 - 0.047 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EDN97785.1 - 0.051 12.7 1.6 0.095 11.8 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDN97785.1 - 0.061 12.9 0.2 0.19 11.3 0.1 1.9 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EDN97785.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EDN97785.1 - 0.13 11.4 0.1 0.27 10.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EDN97785.1 - 0.21 11.0 0.0 4.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DSBA PF01323.15 EDN97786.1 - 2e-16 60.1 0.0 2.3e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 EDN97787.1 - 1.9e-16 60.4 0.0 2.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN97787.1 - 4.2e-08 33.2 0.0 8e-08 32.3 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN97787.1 - 4.7e-08 32.8 0.0 7.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDN97787.1 - 0.046 13.5 0.2 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EDN97787.1 - 0.082 12.9 0.2 0.36 10.7 0.1 1.9 1 1 1 2 2 2 0 NADH(P)-binding Dus PF01207.12 EDN97788.1 - 1.4e-56 191.6 0.0 3.8e-56 190.1 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EDN97788.1 - 0.014 14.4 0.0 0.03 13.2 0.0 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1179 PF06678.6 EDN97789.1 - 0.27 11.5 5.1 0.16 12.3 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) BCNT PF07572.7 EDN97791.1 - 1e-23 83.0 0.1 2.6e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Inhibitor_I53 PF11714.3 EDN97791.1 - 0.85 9.6 4.8 1.2 9.1 0.1 3.1 2 1 1 3 3 3 0 Thrombin inhibitor Madanin Rox3 PF08633.5 EDN97791.1 - 7.5 6.8 13.1 0.094 13.0 2.7 2.4 2 1 1 4 4 4 0 Rox3 mediator complex subunit Acyltransferase PF01553.16 EDN97792.1 - 5.7e-28 96.9 0.0 9.2e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EDN97793.1 - 2.2e-52 177.5 0.0 3.4e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase MFS_1 PF07690.11 EDN97795.1 - 4.4e-30 104.5 36.6 6.3e-30 104.0 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1435 PF07256.7 EDN97795.1 - 0.033 14.1 1.4 0.033 14.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) DUF2283 PF10049.4 EDN97796.1 - 0.22 11.4 0.7 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) adh_short PF00106.20 EDN97798.1 - 0.00098 19.0 0.0 0.0011 18.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Stb3 PF10330.4 EDN97799.1 - 5.3e-37 125.3 0.0 8.7e-37 124.7 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 EDN97801.1 - 9.1e-93 311.2 0.0 1.3e-87 294.2 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EDN97801.1 - 4.4e-17 61.8 0.0 1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 EDN97801.1 - 0.035 14.0 0.0 7.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Toprim domain DUF1295 PF06966.7 EDN97802.1 - 1.5e-23 83.3 5.3 1.9e-23 82.9 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NIDO PF06119.9 EDN97802.1 - 0.013 16.1 0.3 0.21 12.3 0.1 2.3 1 1 1 2 2 2 0 Nidogen-like ICMT PF04140.9 EDN97802.1 - 0.23 11.6 1.9 0.4 10.9 0.1 2.3 1 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Aldolase_2 PF10120.4 EDN97804.1 - 0.12 11.7 0.2 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative aldolase Tropomyosin_1 PF12718.2 EDN97805.1 - 0.0044 16.8 14.9 0.086 12.6 0.0 3.2 2 1 1 3 3 3 1 Tropomyosin like IncA PF04156.9 EDN97805.1 - 0.016 14.7 18.9 0.16 11.5 0.1 2.6 2 1 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EDN97805.1 - 0.025 14.4 19.9 0.8 9.5 0.3 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 EDN97805.1 - 0.032 14.2 12.7 0.24 11.4 2.8 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein DivIVA PF05103.8 EDN97805.1 - 0.044 13.8 9.6 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 DivIVA protein HALZ PF02183.13 EDN97805.1 - 0.12 12.1 2.5 20 4.9 0.0 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Halo_GVPC PF05465.8 EDN97805.1 - 0.14 12.1 0.4 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat TPR_MLP1_2 PF07926.7 EDN97805.1 - 0.2 11.4 16.9 1.7 8.3 9.0 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EDN97805.1 - 0.22 11.3 0.1 0.22 11.3 0.1 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 EDN97805.1 - 0.24 11.3 8.6 0.44 10.5 2.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2968 PF11180.3 EDN97805.1 - 0.26 10.6 11.5 0.83 9.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Prefoldin PF02996.12 EDN97805.1 - 0.35 10.5 6.5 0.76 9.4 0.0 3.1 3 0 0 3 3 3 0 Prefoldin subunit DUF4482 PF14818.1 EDN97805.1 - 0.48 11.0 10.5 0.07 13.7 2.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) Ax_dynein_light PF10211.4 EDN97805.1 - 0.51 10.1 10.9 0.55 10.0 1.2 3.0 2 1 1 3 3 3 0 Axonemal dynein light chain DUF329 PF03884.9 EDN97805.1 - 0.66 9.5 6.4 1.5 8.4 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2730 PF10805.3 EDN97805.1 - 0.7 9.6 5.1 0.96 9.2 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Hemerythrin PF01814.18 EDN97805.1 - 1.6 8.9 5.2 12 6.1 0.3 3.0 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain HCMV_UL139 PF12507.3 EDN97805.1 - 4.1 7.5 7.9 18 5.5 0.3 2.5 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein bZIP_2 PF07716.10 EDN97805.1 - 6.1 6.7 11.7 1.6 8.6 0.1 3.6 3 0 0 3 3 3 0 Basic region leucine zipper APG6 PF04111.7 EDN97805.1 - 6.8 5.6 16.0 9 5.2 0.3 2.4 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF2205 PF10224.4 EDN97805.1 - 7.1 6.2 11.6 2.7 7.6 0.2 3.4 4 0 0 4 4 3 0 Predicted coiled-coil protein (DUF2205) DUF4140 PF13600.1 EDN97805.1 - 8.2 6.9 13.6 0.29 11.6 0.4 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EDN97805.1 - 9.3 5.8 10.7 8.1 6.0 0.1 3.3 2 1 2 4 4 4 0 Septum formation initiator MIF4G PF02854.14 EDN97807.1 - 5e-27 94.6 1.0 1e-26 93.6 0.2 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EDN97807.1 - 1.2e-25 89.3 0.0 6e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 MA3 domain Peptidase_M26_N PF05342.9 EDN97807.1 - 0.023 13.6 0.3 0.04 12.9 0.2 1.4 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region CENP-B_dimeris PF09026.5 EDN97807.1 - 0.29 11.3 7.8 2.8 8.2 4.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.8 EDN97807.1 - 0.62 9.9 6.0 1.4 8.7 4.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.7 EDN97807.1 - 7 5.8 6.6 12 5.0 4.6 1.3 1 0 0 1 1 1 0 NOA36 protein DPM2 PF07297.7 EDN97808.1 - 2.2e-35 120.7 3.1 2.6e-35 120.5 2.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EDN97808.1 - 1.4e-05 24.7 1.6 1.7e-05 24.4 1.1 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EDN97808.1 - 0.00041 20.1 0.9 0.00041 20.1 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) Cytochrom_C_asm PF01578.15 EDN97808.1 - 0.004 16.7 0.5 0.0044 16.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF1049 PF06305.6 EDN97808.1 - 0.025 14.0 0.2 0.025 14.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DiS_P_DiS PF06750.8 EDN97808.1 - 0.062 13.1 0.6 0.092 12.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF588 PF04535.7 EDN97808.1 - 0.082 12.4 0.5 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF1469 PF07332.6 EDN97808.1 - 0.088 12.5 1.6 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4083 PF13314.1 EDN97808.1 - 0.093 12.5 0.2 0.093 12.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) COX14 PF14880.1 EDN97808.1 - 0.096 12.3 2.9 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TPPK_C PF12555.3 EDN97808.1 - 0.13 11.9 9.0 0.14 11.9 1.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YajC PF02699.10 EDN97808.1 - 1.4 8.6 3.6 0.8 9.4 0.1 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit HLH PF00010.21 EDN97813.1 - 1.2e-13 50.5 0.1 3.9e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Pcc1 PF09341.5 EDN97814.1 - 1.3e-24 85.9 0.8 1.8e-24 85.5 0.6 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EDN97815.1 - 2.8e-42 144.0 0.0 1.4e-40 138.5 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EDN97815.1 - 1.1e-14 54.0 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN97815.1 - 1.7e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EF-hand_1 PF00036.27 EDN97816.1 - 0.078 12.3 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 EF hand Flg_bb_rod PF00460.15 EDN97820.1 - 0.038 13.7 0.3 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Flagella basal body rod protein Ank_4 PF13637.1 EDN97822.1 - 0.021 15.3 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN97822.1 - 0.028 14.7 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN97822.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN97822.1 - 0.04 14.1 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeat DUF706 PF05153.10 EDN97823.1 - 2.4e-99 331.7 1.7 2.8e-99 331.5 1.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EDN97823.1 - 0.0077 16.2 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 2 HD domain HDOD PF08668.7 EDN97823.1 - 0.014 14.6 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 HDOD domain DUF397 PF04149.7 EDN97823.1 - 0.048 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF397) ADH_N PF08240.7 EDN97824.1 - 5.4e-30 103.3 0.5 1.1e-29 102.3 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN97824.1 - 2.3e-18 65.9 0.1 3.8e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EDN97824.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 ThiF family Methyltransf_18 PF12847.2 EDN97824.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_2 PF00890.19 EDN97824.1 - 0.028 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EDN97824.1 - 0.028 13.5 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDN97824.1 - 0.03 13.7 0.0 0.072 12.4 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EDN97824.1 - 0.035 13.9 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 EDN97824.1 - 0.12 12.6 0.1 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDN97824.1 - 0.13 12.3 0.9 0.75 9.8 0.6 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EDN97825.1 - 2.1e-31 109.0 0.2 2.8e-31 108.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN97825.1 - 4.1e-19 69.3 0.0 5.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN97825.1 - 2.2e-13 50.2 0.2 4.9e-13 49.1 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN97825.1 - 2.4e-08 33.7 0.0 3.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDN97825.1 - 0.0004 20.0 0.3 0.00075 19.2 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EDN97825.1 - 0.029 14.3 0.5 0.12 12.3 0.4 2.2 1 1 0 1 1 1 0 NADH(P)-binding NUDIX_4 PF14815.1 EDN97826.1 - 0.05 13.0 0.9 0.3 10.5 0.6 1.9 1 1 0 1 1 1 0 NUDIX domain AP3B1_C PF14796.1 EDN97826.1 - 0.98 9.0 4.8 1.2 8.8 3.4 1.1 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Apc15p PF05841.6 EDN97826.1 - 2.5 8.8 7.2 3.8 8.2 5.0 1.3 1 0 0 1 1 1 0 Apc15p protein SR-25 PF10500.4 EDN97826.1 - 3.7 6.9 15.0 6 6.2 10.4 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myc_N PF01056.13 EDN97829.1 - 0.065 12.3 2.0 0.062 12.4 1.4 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Brevenin PF03032.10 EDN97829.1 - 1.8 8.4 6.3 2.3 8.1 4.4 1.3 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family dUTPase PF00692.14 EDN97830.1 - 7e-43 145.1 0.0 9.9e-43 144.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase Pex14_N PF04695.8 EDN97830.1 - 2.4 8.1 5.9 3.6 7.6 4.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EDN97830.1 - 7.2 5.8 9.1 7.7 5.8 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Phos_pyr_kin PF08543.7 EDN97831.1 - 2.3e-11 43.3 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EDN97831.1 - 1.5e-06 27.5 0.1 7.1e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Sugar_tr PF00083.19 EDN97832.1 - 5.6e-106 354.8 22.3 8.7e-106 354.1 15.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter PCNA_N PF00705.13 EDN97832.1 - 2e-53 179.2 3.5 2e-53 179.2 2.4 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EDN97832.1 - 2.7e-49 166.3 0.0 7.8e-49 164.8 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain MFS_1 PF07690.11 EDN97832.1 - 5.1e-27 94.5 29.4 7.4e-27 93.9 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Rad9 PF04139.8 EDN97832.1 - 7.6e-09 35.0 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 TRI12 PF06609.8 EDN97832.1 - 0.00013 20.2 5.1 0.00013 20.2 3.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Hus1 PF04005.7 EDN97832.1 - 0.0029 16.6 0.2 0.011 14.7 0.1 1.8 1 1 1 2 2 2 1 Hus1-like protein MFS_1 PF07690.11 EDN97836.1 - 3.3e-28 98.4 18.2 3.3e-28 98.4 12.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIA PF03153.8 EDN97837.1 - 9.5 5.9 16.3 0.013 15.4 3.1 2.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Membr_traf_MHD PF10540.4 EDN97838.1 - 3.1e-25 88.5 0.2 8.3e-25 87.1 0.2 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EDN97838.1 - 1.7e-16 59.8 0.0 4.6e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EDN97838.1 - 3.3e-05 22.4 0.4 7.1e-05 21.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF810) HAMP PF00672.20 EDN97840.1 - 3.6e-49 164.8 21.8 1.5e-10 41.0 0.3 7.4 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.21 EDN97840.1 - 6e-29 100.0 0.1 2.2e-28 98.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN97840.1 - 9e-27 93.3 1.8 6.1e-26 90.6 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EDN97840.1 - 4e-18 65.1 0.5 4e-18 65.1 0.4 4.6 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EDN97840.1 - 3.5e-05 22.5 20.0 0.0027 16.2 0.9 3.9 1 1 2 4 4 4 3 AAA domain DUF4279 PF14106.1 EDN97840.1 - 0.011 15.5 0.0 7.2 6.5 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4279) DUF2365 PF10157.4 EDN97840.1 - 0.057 13.3 14.2 7.4 6.4 0.0 6.6 6 1 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) DUF883 PF05957.8 EDN97840.1 - 0.34 11.3 20.3 2.6 8.5 0.1 6.5 4 2 2 7 7 7 0 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 EDN97840.1 - 0.5 10.7 6.0 31 4.9 0.0 5.9 5 2 3 8 8 8 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TSC22 PF01166.13 EDN97840.1 - 0.69 9.9 14.5 22 5.1 0.1 5.9 5 0 0 5 5 5 0 TSC-22/dip/bun family Tho2 PF11262.3 EDN97840.1 - 1.2 8.0 4.9 0.47 9.4 1.2 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Rotamase PF00639.16 EDN97840.1 - 4.9 7.9 13.0 18 6.1 0.3 5.4 4 2 1 5 5 5 0 PPIC-type PPIASE domain MBOAT_2 PF13813.1 EDN97842.1 - 3.6e-14 52.5 0.9 1e-13 51.1 0.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EDN97844.1 - 3.8e-32 111.3 29.0 5.7e-32 110.8 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN97844.1 - 1.8e-06 26.6 7.8 1.8e-06 26.6 5.4 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Fungal_trans_2 PF11951.3 EDN97845.1 - 1.4e-81 274.1 0.2 1.8e-81 273.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN97845.1 - 7.2e-06 25.8 7.7 1.3e-05 24.9 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EDN97847.1 - 1.1e-08 34.7 0.1 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDN97847.1 - 1.3e-08 34.8 0.1 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EDN97847.1 - 3.1e-05 24.1 0.0 0.00013 22.1 0.0 2.1 1 1 0 1 1 1 1 PH domain SAM_PNT PF02198.11 EDN97847.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RabGAP-TBC PF00566.13 EDN97848.1 - 1.4e-36 125.9 0.0 2.5e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ESCRT-II PF05871.7 EDN97849.1 - 3.1e-48 163.2 0.0 5.3e-48 162.4 0.0 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit FeoC PF09012.5 EDN97849.1 - 0.018 14.7 0.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator p450 PF00067.17 EDN97854.1 - 7.4e-55 186.2 0.0 1.4e-54 185.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.17 EDN97855.1 - 1.4e-49 168.3 4.3 1.6e-49 168.0 3.0 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EDN97855.1 - 0.0017 17.9 0.1 0.0021 17.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDN97855.1 - 0.0028 17.2 0.1 0.0034 16.9 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EDN97855.1 - 0.0036 16.7 0.2 0.0049 16.3 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EDN97855.1 - 0.0062 16.2 0.9 0.011 15.5 0.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EDN97855.1 - 0.0093 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) VirJ PF06057.6 EDN97855.1 - 0.038 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.15 EDN97855.1 - 0.038 14.1 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 EDN97855.1 - 0.047 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EDN97855.1 - 0.061 12.8 0.3 0.061 12.8 0.2 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EDN97855.1 - 0.062 12.5 0.3 0.086 12.1 0.2 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family BetaGal_dom2 PF10435.4 EDN97855.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 PGAP1 PF07819.8 EDN97855.1 - 0.17 11.4 0.3 0.23 11.0 0.2 1.1 1 0 0 1 1 1 0 PGAP1-like protein RVT_2 PF07727.9 EDN97858.1 - 1.1e-15 57.2 0.0 2.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN97858.1 - 2.7e-06 27.7 1.1 5.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 RNase H rve PF00665.21 EDN97858.1 - 7.6e-05 22.8 0.0 0.00036 20.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN97858.1 - 7.9e-05 22.2 0.5 0.00027 20.5 0.4 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain NmrA PF05368.8 EDN97862.1 - 8.7e-31 106.9 0.0 4.6e-29 101.3 0.0 2.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN97862.1 - 4.5e-10 39.8 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN97862.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDN97862.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S28e PF01200.13 EDN97862.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S28e AA_permease_2 PF13520.1 EDN97865.1 - 1.2e-05 24.1 6.9 1.4e-05 23.8 4.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN97865.1 - 0.0012 17.3 4.1 0.0014 17.0 2.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN97866.1 - 1.6e-08 33.5 4.8 1.7e-08 33.4 3.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN97866.1 - 0.00068 18.0 1.8 0.00068 18.0 1.3 1.1 1 0 0 1 1 1 1 Amino acid permease zf-CCHC PF00098.18 EDN97868.1 - 0.029 14.3 4.8 0.051 13.5 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN97868.1 - 0.27 10.9 3.2 0.61 9.7 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_psq PF05225.11 EDN97869.1 - 1.5e-07 30.8 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Ribosomal_S13_N PF08069.7 EDN97869.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain HTH_29 PF13551.1 EDN97869.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn helix RIO1 PF01163.17 EDN97869.1 - 0.031 13.6 0.2 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family HTH_Tnp_Tc5 PF03221.11 EDN97869.1 - 0.086 12.6 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Abhydrolase_5 PF12695.2 EDN97870.1 - 8e-06 25.6 1.7 9.4e-05 22.1 0.1 3.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN97870.1 - 1.6e-05 24.9 0.0 0.00011 22.2 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family SKG6 PF08693.5 EDN97871.1 - 0.0021 17.3 1.2 0.0059 15.9 0.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ABC2_membrane_3 PF12698.2 EDN97871.1 - 0.014 14.4 2.9 0.017 14.1 2.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AJAP1_PANP_C PF15298.1 EDN97871.1 - 0.018 14.9 11.3 0.025 14.4 7.8 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Macoilin PF09726.4 EDN97871.1 - 0.18 10.0 7.9 0.22 9.7 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 EDN97871.1 - 0.41 10.1 8.1 0.57 9.6 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RVT_1 PF00078.22 EDN97872.1 - 2.4e-17 62.9 0.0 2.4e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PG_binding_3 PF09374.5 EDN97872.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Predicted Peptidoglycan domain RNase_H PF00075.19 EDN97873.1 - 1.8e-11 44.4 0.0 3.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNase H AAA_16 PF13191.1 EDN97874.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EDN97874.1 - 0.021 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EDN97874.1 - 0.036 14.2 0.1 0.04 14.1 0.1 1.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EDN97874.1 - 0.077 12.3 0.0 0.095 12.0 0.0 1.3 1 1 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.1 EDN97874.1 - 0.077 13.1 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN97874.1 - 0.11 13.3 0.1 0.11 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDN97874.1 - 0.11 11.3 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.1 EDN97874.1 - 0.11 10.8 0.1 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.14 EDN97875.1 - 2.4e-18 66.0 0.0 3.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN97875.1 - 1.6e-14 53.4 0.0 4e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN97875.1 - 3e-06 27.0 0.2 7.2e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Ank_2 PF12796.2 EDN97876.1 - 2.4e-23 82.2 0.0 9e-19 67.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN97876.1 - 4e-16 57.9 0.0 4.5e-07 29.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EDN97876.1 - 5.2e-15 55.1 0.0 2.6e-07 30.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN97876.1 - 2.4e-14 53.3 0.0 2.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN97876.1 - 1.1e-12 46.8 0.0 4.4e-05 23.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat HET PF06985.6 EDN97877.1 - 0.0001 22.4 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) INCENP_ARK-bind PF03941.10 EDN97877.1 - 0.15 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Thioredoxin_3 PF13192.1 EDN97882.1 - 0.68 9.7 4.0 1 9.2 2.8 1.3 1 0 0 1 1 1 0 Thioredoxin domain bZIP_1 PF00170.16 EDN97884.1 - 1.9e-05 24.5 1.6 1.9e-05 24.5 1.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor Nif11 PF07862.6 EDN97884.1 - 0.18 11.7 2.5 12 5.9 0.0 3.1 2 1 1 3 3 3 0 Nitrogen fixation protein of unknown function bZIP_Maf PF03131.12 EDN97884.1 - 9.1 6.6 13.2 0.44 10.8 3.4 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor Rcd1 PF04078.8 EDN97886.1 - 1.7e-96 322.1 3.4 2.8e-86 288.6 0.2 2.1 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like OSCP PF00213.13 EDN97886.1 - 0.099 12.4 0.9 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit BAF1_ABF1 PF04684.8 EDN97886.1 - 2 7.1 14.3 2.7 6.7 9.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Na_Ca_ex PF01699.19 EDN97887.1 - 4.6e-49 165.6 33.3 1.7e-25 89.2 2.8 3.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 EDN97888.1 - 3.2e-213 710.2 6.4 1.2e-147 493.5 0.1 2.0 2 0 0 2 2 2 2 Condensin complex subunit 2 DUF912 PF06024.7 EDN97888.1 - 0.036 14.1 1.6 0.75 9.8 0.4 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EDN97888.1 - 0.091 13.0 0.1 0.091 13.0 0.0 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 EDN97890.1 - 2.2e-30 105.5 38.4 2.2e-30 105.5 26.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN97890.1 - 8.5e-06 24.6 29.9 3e-05 22.7 20.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter F-box-like PF12937.2 EDN97892.1 - 0.00021 20.9 0.0 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like TFIIE-A_C-term PF11521.3 EDN97892.1 - 0.035 14.0 2.6 0.11 12.4 1.8 1.9 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha WD40 PF00400.27 EDN97893.1 - 2.7e-46 153.8 16.1 1.1e-08 34.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDN97893.1 - 0.00053 19.7 11.6 0.15 11.7 0.1 4.4 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term Polysacc_synt_2 PF02719.10 EDN97893.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IKI3 PF04762.7 EDN97893.1 - 0.31 8.7 2.3 8 4.1 0.3 2.3 2 1 0 2 2 2 0 IKI3 family Cytomega_UL84 PF06284.6 EDN97894.1 - 0.38 9.1 2.4 0.61 8.4 1.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MCM PF00493.18 EDN97897.1 - 4.6e-133 443.1 0.0 6.9e-133 442.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN97897.1 - 5.6e-30 104.3 0.4 2.1e-29 102.4 0.1 2.1 2 1 1 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN97897.1 - 1.9e-07 30.4 0.0 1.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN97897.1 - 9.8e-06 25.3 0.0 3.3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EDN97897.1 - 0.002 18.4 0.3 0.01 16.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDN97897.1 - 0.055 13.0 0.1 0.23 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDN97898.1 - 2e-55 186.6 0.0 3.1e-43 147.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EDN97898.1 - 1.7e-28 98.5 0.1 3.3e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EDN97898.1 - 1.4e-12 47.9 3.3 9.5e-08 32.2 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EDN97898.1 - 1.2e-06 29.3 0.0 0.093 13.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EDN97898.1 - 2.3e-06 27.6 0.0 0.078 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EDN97898.1 - 3.3e-06 27.4 0.4 0.0022 18.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN97898.1 - 4.1e-06 26.9 0.3 0.17 12.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EDN97898.1 - 7e-06 26.1 0.0 0.0013 18.8 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EDN97898.1 - 7.5e-06 25.8 0.0 0.054 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN97898.1 - 7.9e-06 25.1 0.0 0.011 14.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 EDN97898.1 - 9e-06 24.9 0.0 0.012 14.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDN97898.1 - 1.3e-05 24.9 0.2 0.031 14.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN97898.1 - 2.4e-05 23.9 0.0 0.059 13.1 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EDN97898.1 - 5.5e-05 22.8 1.0 0.075 12.6 0.0 3.9 3 1 0 3 3 3 1 NACHT domain AAA_33 PF13671.1 EDN97898.1 - 0.00012 21.9 0.0 0.42 10.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDN97898.1 - 0.00015 21.2 0.2 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein UPF0079 PF02367.12 EDN97898.1 - 0.00024 20.7 0.0 0.0034 17.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EDN97898.1 - 0.00063 19.2 0.0 0.024 14.1 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.1 EDN97898.1 - 0.0018 18.2 0.1 0.93 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDN97898.1 - 0.0023 17.1 0.6 0.85 8.7 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EDN97898.1 - 0.0031 16.9 3.1 12 5.2 0.1 4.2 2 2 1 4 4 4 0 AAA domain KAP_NTPase PF07693.9 EDN97898.1 - 0.0037 16.3 0.1 0.043 12.8 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain SKI PF01202.17 EDN97898.1 - 0.0048 16.7 0.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.13 EDN97898.1 - 0.0055 16.2 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EDN97898.1 - 0.0064 16.7 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.8 EDN97898.1 - 0.011 14.6 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EDN97898.1 - 0.012 14.3 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus NB-ARC PF00931.17 EDN97898.1 - 0.018 13.8 0.0 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EDN97898.1 - 0.024 14.8 0.0 8.2 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EDN97898.1 - 0.047 13.3 0.1 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase KaiC PF06745.8 EDN97898.1 - 0.11 11.6 0.0 18 4.3 0.0 2.5 2 0 0 2 2 2 0 KaiC cobW PF02492.14 EDN97898.1 - 0.15 11.4 0.7 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_3 PF07726.6 EDN97898.1 - 0.16 11.6 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PBP_like_2 PF12849.2 EDN97900.1 - 0.0046 16.4 0.0 0.0088 15.5 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain AT_hook PF02178.14 EDN97901.1 - 1.9 8.4 14.7 0.34 10.7 2.9 3.0 2 0 0 2 2 2 0 AT hook motif Pam17 PF08566.5 EDN97902.1 - 3.3e-69 232.0 0.1 4.4e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ThiF PF00899.16 EDN97903.1 - 2.6e-28 98.5 4.2 2e-19 69.7 0.5 2.6 2 1 1 3 3 3 2 ThiF family MoeZ_MoeB PF05237.8 EDN97903.1 - 5.8e-21 73.8 1.2 3.1e-20 71.5 0.8 2.1 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EDN97903.1 - 6.9e-12 45.7 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EDN97903.1 - 4.4e-05 23.6 0.2 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDN97903.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FlxA PF14282.1 EDN97903.1 - 0.089 12.7 1.1 0.22 11.4 0.8 1.6 1 0 0 1 1 1 0 FlxA-like protein CENP-Q PF13094.1 EDN97903.1 - 0.26 11.2 4.4 0.47 10.4 3.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SLX9 PF15341.1 EDN97904.1 - 1.6e-37 128.6 3.5 1.9e-37 128.3 2.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 AP_endonuc_2 PF01261.19 EDN97905.1 - 7.6e-33 113.5 0.0 9.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_C48 PF02902.14 EDN97906.1 - 5.6e-18 65.3 0.0 1.6e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CVNH PF08881.5 EDN97909.1 - 6.5e-32 109.8 0.1 7.2e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 CVNH domain CTNNBL PF08216.6 EDN97909.1 - 0.081 12.5 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear CBM_1 PF00734.13 EDN97911.1 - 6e-07 29.0 5.7 1.7e-06 27.5 3.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3439 PF11921.3 EDN97911.1 - 6.7 6.4 13.9 2.2 8.0 4.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DAP3 PF10236.4 EDN97912.1 - 4.8e-102 341.0 0.0 5.8e-102 340.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.7 EDN97913.1 - 1e-58 197.4 3.2 1.2e-58 197.2 2.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EDN97914.1 - 2.6e-27 95.2 0.0 5.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain adh_short PF00106.20 EDN97916.1 - 4.2e-17 62.5 0.0 1.1e-15 57.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN97916.1 - 2.9e-06 27.0 0.1 2.3e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDN97916.1 - 0.0012 18.6 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN97916.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EDN97916.1 - 0.044 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EDN97916.1 - 0.081 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EDN97916.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1180 PF06679.7 EDN97917.1 - 0.092 12.6 0.3 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Glycophorin_A PF01102.13 EDN97917.1 - 0.32 10.7 1.8 0.31 10.7 0.1 1.9 2 1 0 2 2 2 0 Glycophorin A CFEM PF05730.6 EDN97917.1 - 3.3 7.6 10.8 8.6 6.2 7.5 1.7 1 1 0 1 1 1 0 CFEM domain DUF4231 PF14015.1 EDN97917.1 - 3.5 7.6 8.0 36 4.3 5.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) RRM_6 PF14259.1 EDN97918.1 - 0.021 14.7 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YXWGXW PF12779.2 EDN97918.1 - 0.28 11.1 1.3 0.57 10.1 0.9 1.5 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) MMPL PF03176.10 EDN97919.1 - 0.13 10.9 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 MMPL family Abhydrolase_6 PF12697.2 EDN97921.1 - 7.8e-25 88.0 0.1 9.4e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN97921.1 - 4.1e-15 55.9 0.0 1.8e-14 53.9 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN97921.1 - 2e-09 37.3 0.0 5.3e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDN97921.1 - 0.026 14.1 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EDN97921.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 EDN97921.1 - 0.047 13.4 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EDN97921.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3328 PF11807.3 EDN97922.1 - 3.2e-13 49.8 0.2 2.1e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Phage_holin_6 PF10746.4 EDN97925.1 - 0.081 12.6 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Phage holin family 6 AA_permease_2 PF13520.1 EDN97926.1 - 2e-37 128.7 45.7 8.7e-28 97.0 6.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN97926.1 - 2.5e-14 52.5 36.6 3.3e-12 45.5 5.5 2.2 1 1 1 2 2 2 2 Amino acid permease RVT_2 PF07727.9 EDN97932.1 - 3e-50 170.4 0.0 3.5e-49 166.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN97932.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN97932.1 - 0.00017 21.1 0.7 0.0005 19.6 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN97932.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) HhH-GPD PF00730.20 EDN97934.1 - 0.0015 18.7 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PBD PF00786.23 EDN97934.1 - 0.11 12.9 0.6 0.77 10.2 0.1 2.2 2 0 0 2 2 2 0 P21-Rho-binding domain Cytochrom_C1 PF02167.10 EDN97936.1 - 2.5e-78 262.6 0.0 3.3e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EDN97936.1 - 0.0073 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EDN97936.1 - 0.099 13.4 0.2 0.3 11.9 0.2 2.0 1 1 0 1 1 1 0 Cytochrome c Shadoo PF14999.1 EDN97936.1 - 0.21 11.4 3.3 6.7 6.5 2.1 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DAHP_synth_1 PF00793.15 EDN97937.1 - 5e-100 333.6 0.0 6.1e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family NAD_Gly3P_dh_N PF01210.18 EDN97938.1 - 5.2e-45 152.9 0.1 1.1e-44 151.9 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EDN97938.1 - 3.2e-40 137.2 0.1 4.7e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Malic_M PF03949.10 EDN97938.1 - 0.092 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain hGDE_central PF14702.1 EDN97939.1 - 3e-91 305.1 0.0 1.2e-90 303.2 0.0 2.0 3 0 0 3 3 3 1 central domain of human glycogen debranching enzyme GDE_C PF06202.9 EDN97939.1 - 2.5e-70 237.0 0.0 3.7e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hDGE_amylase PF14701.1 EDN97939.1 - 1.5e-58 198.6 0.0 2.4e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme hGDE_N PF14699.1 EDN97939.1 - 2.9e-23 81.5 0.8 1e-22 79.7 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain from the human glycogen debranching enzyme Far-17a_AIG1 PF04750.9 EDN97941.1 - 4.4e-62 208.8 13.2 5e-62 208.6 9.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pro_isomerase PF00160.16 EDN97942.1 - 1.8e-50 171.1 0.2 4.7e-50 169.8 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EDN97942.1 - 0.00019 21.1 0.0 0.41 10.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DeoC PF01791.4 EDN97942.1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase Fungal_trans_2 PF11951.3 EDN97943.1 - 6.9e-57 192.7 1.1 9.5e-57 192.3 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN97943.1 - 6.1e-09 35.6 9.5 1.4e-08 34.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A2M_N_2 PF07703.9 EDN97944.1 - 0.024 14.4 0.2 0.11 12.2 0.2 1.9 1 1 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region DUF2246 PF10229.4 EDN97944.1 - 0.49 9.6 4.6 0.62 9.3 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) AMP-binding PF00501.23 EDN97945.1 - 1e-95 320.6 0.0 1.2e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN97945.1 - 5e-12 46.5 0.4 1.9e-11 44.7 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.6 EDN97946.1 - 2.3e-89 299.4 0.0 2.7e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Cas_Cas02710 PF09670.5 EDN97946.1 - 0.037 12.6 0.1 0.06 11.9 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) SseB PF07179.7 EDN97946.1 - 0.087 12.6 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 SseB protein N-terminal domain DUF938 PF06080.7 EDN97946.1 - 0.12 11.8 0.0 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Totivirus_coat PF05518.6 EDN97946.1 - 0.39 8.4 1.4 0.49 8.1 1.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein RHH_1 PF01402.16 EDN97946.1 - 1.9 8.5 6.0 1.3 9.0 0.2 2.8 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family BTB PF00651.26 EDN97948.1 - 1.6e-14 53.8 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DDE_1 PF03184.14 EDN97949.1 - 6e-06 25.5 0.3 9.1e-06 24.9 0.2 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3450 PF11932.3 EDN97949.1 - 0.016 14.4 0.2 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3539 PF12058.3 EDN97949.1 - 0.26 11.1 1.4 0.37 10.6 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3539) Med9 PF07544.8 EDN97949.1 - 9.8 6.0 9.4 1.4 8.6 0.6 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BTB PF00651.26 EDN97950.1 - 3.7e-06 26.8 0.0 7.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EDN97951.1 - 0.0066 16.4 0.1 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain PAT1 PF09770.4 EDN97952.1 - 3.4 5.7 18.1 3.9 5.5 12.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EDN97954.1 - 1.6e-05 24.4 0.0 4.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN97954.1 - 7.3e-05 22.3 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF221 PF02714.10 EDN97955.1 - 1.6e-98 329.5 18.6 2.4e-98 329.0 12.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN97955.1 - 1.5e-43 148.0 0.9 1.5e-43 148.0 0.7 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDN97955.1 - 2.4e-22 79.2 0.0 4.1e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EDN97955.1 - 0.02 13.5 5.2 0.009 14.6 1.6 1.8 2 0 0 2 2 2 0 Calcium-activated chloride channel RRM_6 PF14259.1 EDN97955.1 - 0.039 13.9 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EDN97956.1 - 1.8e-13 50.8 0.0 3.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Glyco_transf_20 PF00982.16 EDN97959.1 - 4.8e-164 546.3 0.1 6.6e-164 545.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDN97959.1 - 8.5e-45 152.4 0.0 1.7e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Tagatose_6_P_K PF08013.6 EDN97959.1 - 0.12 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Aminotran_4 PF01063.14 EDN97960.1 - 2e-25 89.6 0.0 2.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Evr1_Alr PF04777.8 EDN97961.1 - 1.2e-27 95.5 0.2 1.8e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.21 EDN97962.1 - 4.6e-25 88.0 0.0 5.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EDN97963.1 - 3e-39 134.8 1.3 1.9e-22 80.3 0.2 2.5 2 0 0 2 2 2 2 Cyclin YqfQ PF14181.1 EDN97964.1 - 2 8.4 13.7 2.4 8.2 9.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein Proteasome PF00227.21 EDN97965.1 - 2.7e-43 147.4 3.6 3.7e-31 107.8 0.0 2.4 2 1 1 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EDN97965.1 - 5.4e-12 44.7 0.0 1.3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HATPase_c PF02518.21 EDN97971.1 - 7.9e-19 67.4 0.5 3.4e-18 65.3 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.15 EDN97971.1 - 1.2e-17 63.6 0.0 2.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.19 EDN97971.1 - 7e-16 58.2 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EDN97971.1 - 5.3e-12 46.1 0.0 1.2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.6 EDN97971.1 - 1e-07 32.3 0.0 3.1e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 EDN97971.1 - 2.6e-06 27.3 0.9 5.8e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EDN97971.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bestrophin PF01062.16 EDN97972.1 - 0.061 12.2 4.6 0.068 12.0 3.2 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Peptidase_S49_N PF08496.5 EDN97972.1 - 0.21 11.3 0.1 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SUR7 PF06687.7 EDN97972.1 - 5.6 6.4 12.6 6.8 6.1 8.7 1.1 1 0 0 1 1 1 0 SUR7/PalI family Fungal_trans PF04082.13 EDN97973.1 - 2.3e-10 39.8 0.4 2.3e-10 39.8 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Metal_CEHH PF14455.1 EDN97973.1 - 0.032 13.6 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 Predicted metal binding domain zf-C2H2 PF00096.21 EDN97974.1 - 0.00011 22.3 1.5 0.00014 22.0 1.0 1.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN97974.1 - 0.00017 21.6 1.1 0.00023 21.2 0.7 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger DUF2116 PF09889.4 EDN97974.1 - 0.08 12.7 0.1 0.08 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) GATA PF00320.22 EDN97974.1 - 0.093 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 GATA zinc finger zf-H2C2_2 PF13465.1 EDN97974.1 - 0.58 10.5 2.1 0.81 10.0 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDN97974.1 - 0.69 9.8 3.5 0.99 9.4 2.4 1.4 1 1 0 1 1 1 0 C2H2-type zinc finger UvrD_C PF13361.1 EDN97976.1 - 1.8e-73 248.0 0.0 2.8e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EDN97976.1 - 3.2e-60 204.0 1.3 5.8e-59 199.9 0.9 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EDN97976.1 - 1.6e-14 53.9 0.0 5.7e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EDN97976.1 - 3.5e-11 42.7 0.3 1.3e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDN97976.1 - 1.2e-07 31.5 0.4 2.5e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EDN97976.1 - 1.3e-05 24.8 0.0 0.5 9.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EDN97976.1 - 0.007 15.7 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain UCR_TM PF02921.9 EDN97976.1 - 0.061 13.5 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region AAA_22 PF13401.1 EDN97976.1 - 0.075 13.1 1.5 4.4 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Hexokinase_1 PF00349.16 EDN97977.1 - 2.2e-32 112.0 0.0 3.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EDN97977.1 - 2.5e-32 112.0 0.0 3.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.15 EDN97978.1 - 9.5e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Amidohydro_4 PF13147.1 EDN97979.1 - 1.2e-12 48.5 0.4 5.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EDN97979.1 - 1.5e-08 34.6 0.1 4.4e-07 29.8 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EDN97979.1 - 6.8e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EDN97979.1 - 1.4e-05 24.8 0.0 3.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_3 PF00933.16 EDN97980.1 - 3.6e-54 183.7 0.0 5.6e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN97980.1 - 0.0002 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EDN97980.1 - 0.0022 17.9 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN97980.1 - 0.0041 17.2 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.12 EDN97982.1 - 1.5e-81 272.7 0.2 2.3e-81 272.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EDN97982.1 - 1.2e-65 220.6 0.0 2e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.14 EDN97982.1 - 2.2e-30 104.7 0.0 6.5e-30 103.2 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EDN97982.1 - 1e-25 90.7 0.0 2.4e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 HMGL-like CPSase_L_chain PF00289.17 EDN97982.1 - 1.2e-23 83.3 0.0 3.6e-23 81.7 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN97982.1 - 2.6e-21 76.1 0.1 5.9e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EDN97982.1 - 4.7e-18 64.6 5.7 6.7e-18 64.1 2.5 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EDN97982.1 - 5.7e-16 58.1 0.0 4.1e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN97982.1 - 5.4e-12 45.5 0.0 9.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EDN97982.1 - 7.5e-10 38.3 2.4 3.7e-07 29.7 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 EDN97982.1 - 9.2e-09 34.8 0.1 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDN97982.1 - 1.1e-06 28.2 0.1 2.9e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EDN97982.1 - 0.00012 22.0 0.1 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EDN97982.1 - 0.00012 21.3 0.1 0.077 12.1 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EDN97982.1 - 0.00015 22.0 0.1 0.01 16.1 0.1 3.3 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EDN97982.1 - 0.0014 18.0 0.1 0.0046 16.3 0.0 1.9 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EDN97982.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 EDN97982.1 - 0.029 13.5 0.2 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 EDN97982.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Clathrin PF00637.15 EDN97983.1 - 2.6e-201 659.2 28.1 5.6e-33 113.5 1.9 7.8 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EDN97983.1 - 1.8e-30 104.6 0.3 1.3e-29 101.8 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EDN97983.1 - 2.9e-27 93.0 0.2 0.00041 20.4 0.0 7.8 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin-link PF09268.5 EDN97983.1 - 8.2e-05 21.5 0.1 0.00024 20.0 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 EDN97983.1 - 0.0028 17.5 8.9 0.97 9.4 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN97983.1 - 0.0083 15.8 12.1 15 5.6 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2191 PF09957.4 EDN97983.1 - 0.071 12.9 0.5 0.7 9.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_8 PF13181.1 EDN97983.1 - 0.13 12.1 3.2 34 4.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN97983.1 - 0.25 10.9 3.2 13 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN97983.1 - 0.3 11.1 7.3 6.2 6.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN97983.1 - 3 8.7 17.2 35 5.4 0.0 8.8 13 1 1 14 14 8 0 Tetratricopeptide repeat MFS_1 PF07690.11 EDN97985.1 - 2.4e-40 138.3 51.8 2.4e-40 138.3 35.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN97985.1 - 2.1e-07 29.5 26.6 3e-07 29.0 18.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PsbL PF02419.12 EDN97985.1 - 5.8 6.4 6.4 0.75 9.2 0.5 2.5 2 0 0 2 2 2 0 PsbL protein GTP_EFTU PF00009.22 EDN97986.1 - 8.6e-38 129.6 0.0 1.4e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EDN97986.1 - 1.3e-36 124.5 0.5 2.8e-36 123.4 0.4 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EDN97986.1 - 2.3e-10 40.4 0.6 5.5e-10 39.2 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN97986.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1640 PF07798.6 EDN97987.1 - 1.1e-65 220.9 6.5 1.3e-65 220.7 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 EDN97987.1 - 0.25 11.2 2.6 1.1 9.1 1.8 2.3 1 1 0 1 1 1 0 cwf21 domain UBA PF00627.26 EDN97989.1 - 0.061 13.1 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain Orthopox_F6 PF06601.7 EDN97989.1 - 0.072 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Orthopoxvirus F6 protein Pkinase PF00069.20 EDN97991.1 - 1.8e-53 181.3 0.0 3.8e-33 114.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN97991.1 - 5.3e-41 140.4 0.0 2.9e-24 85.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN97991.1 - 0.0091 14.9 0.0 0.88 8.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like ABC1 PF03109.11 EDN97991.1 - 0.024 14.5 0.0 0.094 12.6 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Thioredoxin_7 PF13899.1 EDN97993.1 - 2.1e-16 59.7 0.0 6.5e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EDN97993.1 - 5.4e-12 45.0 0.0 1.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EDN97993.1 - 6.9e-07 29.2 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.1 EDN97993.1 - 0.046 13.9 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EDN97993.1 - 0.051 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PITH PF06201.8 EDN97995.1 - 3.9e-40 137.1 0.0 5.8e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EDN97995.1 - 2.5e-29 101.0 0.1 5.1e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDN97995.1 - 5.7e-08 32.7 0.0 2.3e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDN97995.1 - 7.2e-07 29.3 0.3 3.4e-06 27.2 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EDN97995.1 - 7.2e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EDN97995.1 - 0.0024 17.3 0.2 0.032 13.7 0.1 2.3 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EDN97995.1 - 0.0042 16.7 0.2 0.12 12.0 0.0 2.4 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EDN97995.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EDN97995.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 EDN97995.1 - 0.075 13.0 0.5 1 9.3 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin PH PF00169.24 EDN98000.1 - 7.9e-06 26.0 0.1 0.00023 21.3 0.0 3.2 4 0 0 4 4 4 1 PH domain PP2C_2 PF13672.1 EDN98001.1 - 0.00029 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDN98001.1 - 0.00091 18.9 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EDN98001.1 - 0.0037 16.6 0.0 0.35 10.2 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C DUF726 PF05277.7 EDN98002.1 - 2.8e-125 417.7 0.6 4e-125 417.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.7 EDN98002.1 - 2.1e-29 101.5 0.0 4.6e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Fcf1 Lipase_3 PF01764.20 EDN98002.1 - 0.036 13.6 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Mtf2_C PF14061.1 EDN98003.1 - 0.12 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 TMEM154 PF15102.1 EDN98004.1 - 0.012 15.3 0.3 0.026 14.2 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family IncA PF04156.9 EDN98004.1 - 1.2 8.6 3.8 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein HpcH_HpaI PF03328.9 EDN98005.1 - 2.6e-41 140.9 0.0 5.3e-41 139.9 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EDN98005.1 - 1.2e-15 57.1 0.0 3.4e-07 29.4 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Hep_59 PF07052.6 EDN98006.1 - 3.5e-15 56.2 0.1 3.5e-15 56.2 0.1 2.8 3 0 0 3 3 3 2 Hepatocellular carcinoma-associated antigen 59 Lactamase_B_3 PF13483.1 EDN98007.1 - 1.7e-07 31.0 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EDN98007.1 - 0.0016 17.9 1.0 0.002 17.7 0.7 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RNase_H PF00075.19 EDN98008.1 - 1.1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF993 PF06187.6 EDN98008.1 - 0.031 12.8 0.0 0.057 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) zf-UDP PF14569.1 EDN98009.1 - 0.051 13.3 6.1 0.1 12.3 4.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger FAD_binding_4 PF01565.18 EDN98010.1 - 2.8e-09 36.5 0.3 0.0015 18.0 0.2 2.4 1 1 1 2 2 2 2 FAD binding domain EF-hand_5 PF13202.1 EDN98010.1 - 0.0095 15.2 0.1 0.028 13.7 0.1 1.8 1 0 0 1 1 1 1 EF hand ALO PF04030.9 EDN98010.1 - 0.033 13.7 0.5 0.83 9.1 0.1 2.2 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase EF-hand_1 PF00036.27 EDN98010.1 - 0.047 12.9 0.3 0.14 11.5 0.2 1.8 1 0 0 1 1 1 0 EF hand GFA PF04828.9 EDN98013.1 - 3.1e-05 23.8 0.7 3.1e-05 23.8 0.5 1.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EDN98013.1 - 0.064 12.4 0.2 0.064 12.4 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EDN98013.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EDN98013.1 - 0.2 11.1 0.1 0.2 11.1 0.1 2.9 3 0 0 3 3 3 0 A2L zinc ribbon domain AICARFT_IMPCHas PF01808.13 EDN98015.1 - 1.9e-103 345.9 0.0 2.5e-103 345.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EDN98015.1 - 5.8e-25 87.0 0.0 1.1e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF202 PF02656.10 EDN98016.1 - 0.042 14.0 2.2 7.6 6.8 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Chromate_transp PF02417.10 EDN98016.1 - 0.13 11.8 2.3 0.13 11.8 0.4 1.8 2 0 0 2 2 2 0 Chromate transporter DUF3329 PF11808.3 EDN98016.1 - 0.24 11.4 1.5 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) MPC PF03650.8 EDN98017.1 - 5.3e-32 110.2 0.0 6.6e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EDN98018.1 - 1.8e-17 62.6 0.0 2.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EDN98018.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Ribosomal_L5_C PF00673.16 EDN98019.1 - 2.2e-22 78.6 0.0 3.2e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDN98019.1 - 1.8e-21 75.6 0.2 5e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 SNF2_N PF00176.18 EDN98024.1 - 1.2e-51 175.2 0.0 1.7e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN98024.1 - 9.2e-14 51.0 0.1 1.9e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDN98024.1 - 0.00026 19.9 0.0 0.00054 18.8 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EDN98024.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VMA21 PF09446.5 EDN98025.1 - 1.8e-14 53.4 7.6 2.6e-14 52.8 5.2 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF3112 PF11309.3 EDN98025.1 - 0.065 13.0 0.2 0.08 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF2406 PF10295.4 EDN98026.1 - 4.8e-20 71.8 0.8 1.7e-19 70.0 0.6 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) PT PF04886.7 EDN98027.1 - 0.015 14.5 3.2 0.025 13.8 2.2 1.4 1 1 0 1 1 1 0 PT repeat APC_15aa PF05972.6 EDN98027.1 - 0.32 11.0 2.1 67 3.7 0.0 3.0 3 0 0 3 3 3 0 APC 15 residue motif Ribosomal_L35Ae PF01247.13 EDN98028.1 - 1.7e-27 95.0 0.2 2.2e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EDN98028.1 - 0.02 14.8 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain G6PD_C PF02781.11 EDN98029.1 - 8.9e-135 448.2 0.0 1.3e-134 447.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EDN98029.1 - 6.5e-65 218.8 0.0 1.1e-64 218.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EDN98030.1 - 0.0034 16.1 0.2 0.0038 15.9 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SBP_bac_10 PF07596.6 EDN98032.1 - 0.0056 16.7 1.1 0.0066 16.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1559) ADK PF00406.17 EDN98033.1 - 1.5e-45 154.7 0.0 1.9e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EDN98033.1 - 7.7e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN98033.1 - 2.4e-06 28.3 0.0 4e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EDN98033.1 - 3.7e-06 26.4 0.1 0.0058 16.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EDN98033.1 - 0.00015 21.6 0.0 0.00057 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain PAS_7 PF12860.2 EDN98033.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Zeta_toxin PF06414.7 EDN98033.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin PCI PF01399.22 EDN98034.1 - 1.2e-14 54.5 1.7 6.4e-14 52.1 0.2 2.7 3 0 0 3 3 3 1 PCI domain Rep_3 PF01051.16 EDN98034.1 - 0.03 13.9 0.1 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 Initiator Replication protein ATP-cone PF03477.11 EDN98034.1 - 0.043 14.2 0.4 0.21 12.0 0.1 2.2 2 0 0 2 2 2 0 ATP cone domain YTH PF04146.10 EDN98038.1 - 2.8e-58 195.4 0.0 4.7e-58 194.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain HSP20 PF00011.16 EDN98040.1 - 2.1e-19 69.2 2.6 1.8e-14 53.4 1.6 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family HAD PF12710.2 EDN98041.1 - 1.1e-18 68.1 0.3 2.8e-18 66.7 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDN98041.1 - 0.00079 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EDN98041.1 - 0.042 13.4 1.5 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3775 PF12616.3 EDN98041.1 - 0.057 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Proteasome PF00227.21 EDN98042.1 - 8.7e-30 103.4 0.8 1.8e-29 102.3 0.2 1.7 2 1 0 2 2 2 1 Proteasome subunit PI3_PI4_kinase PF00454.22 EDN98043.1 - 1.4e-41 142.4 0.0 1.8e-39 135.6 0.0 2.9 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDN98043.1 - 7e-24 84.0 0.2 2.7e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Methyltransf_18 PF12847.2 EDN98044.1 - 1.7e-10 41.4 0.0 3e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN98044.1 - 1.5e-06 28.5 0.0 2.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN98044.1 - 5.5e-05 22.9 0.0 8.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN98044.1 - 0.0003 21.1 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN98044.1 - 0.00031 20.7 0.0 0.00045 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN98044.1 - 0.00034 21.0 0.0 0.00096 19.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN98044.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDN98044.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN98044.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EDN98044.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.7 EDN98044.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_4 PF02390.12 EDN98044.1 - 0.053 12.5 0.1 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 EDN98044.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EDN98044.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EDN98044.1 - 0.17 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LSM PF01423.17 EDN98045.1 - 4.8e-16 58.0 0.2 5.8e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN98045.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain SpoA PF01052.15 EDN98045.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Rad60-SLD PF11976.3 EDN98046.1 - 3.1e-22 78.0 2.0 5.4e-21 74.0 1.0 2.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TCTP PF00838.12 EDN98046.1 - 0.011 15.7 0.1 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Translationally controlled tumour protein ubiquitin PF00240.18 EDN98046.1 - 0.012 15.0 0.1 0.031 13.6 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin family Put_Phosphatase PF06888.7 EDN98046.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase MR_MLE_C PF13378.1 EDN98048.1 - 1.1e-18 67.2 0.0 6.8e-18 64.6 0.0 2.3 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EDN98048.1 - 1.9e-13 50.7 0.0 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EDN98048.1 - 0.00024 21.0 0.1 0.00099 19.0 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EDN98048.1 - 0.0016 17.4 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Spermine_synth PF01564.12 EDN98049.1 - 1.3e-08 34.0 0.0 2.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EDN98049.1 - 5e-06 26.5 0.0 9.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN98049.1 - 0.0086 16.6 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN98049.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 EDN98049.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Cutinase PF01083.17 EDN98050.1 - 4.2e-51 173.2 2.9 6.3e-51 172.6 2.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EDN98050.1 - 4.1e-05 23.2 0.1 7.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EDN98050.1 - 0.0015 17.9 0.3 0.0029 17.0 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EDN98050.1 - 0.0031 17.2 0.9 0.0046 16.7 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EDN98050.1 - 0.0033 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 EDN98050.1 - 0.0064 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EDN98050.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 EDN98050.1 - 0.043 13.3 0.4 0.066 12.7 0.1 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 EDN98050.1 - 0.11 11.1 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family VPEP PF07589.6 EDN98052.1 - 1.1 9.2 4.3 9.1 6.3 0.3 2.2 2 0 0 2 2 2 0 PEP-CTERM motif APH PF01636.18 EDN98059.1 - 4.1e-09 36.5 0.0 7.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_cc PF11790.3 EDN98060.1 - 1.1e-61 208.2 5.1 1.5e-61 207.9 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WSC PF01822.14 EDN98060.1 - 5.4e-19 67.9 12.9 5.4e-19 67.9 8.9 2.4 2 0 0 2 2 2 1 WSC domain Ecm29 PF13001.2 EDN98063.1 - 5.3e-132 440.8 0.0 1.3e-131 439.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EDN98063.1 - 3.4e-08 32.8 3.3 0.98 9.6 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EDN98063.1 - 4.2e-05 23.8 5.2 5.7 7.5 0.1 7.7 6 1 2 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN98063.1 - 0.00023 21.4 0.0 0.042 14.2 0.0 4.1 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region 14-3-3 PF00244.15 EDN98064.1 - 1.7e-114 380.8 2.0 2.3e-114 380.3 1.4 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EDN98064.1 - 0.0096 15.8 0.2 6.4 6.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 EDN98064.1 - 0.017 14.6 0.4 9.1 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4085 PF13315.1 EDN98064.1 - 0.018 14.4 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) E1-E2_ATPase PF00122.15 EDN98066.1 - 1.9e-64 216.8 6.1 4.3e-63 212.4 3.8 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN98066.1 - 1.8e-44 151.4 7.3 1.8e-44 151.4 5.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN98066.1 - 8.6e-34 117.8 0.0 7.6e-33 114.7 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN98066.1 - 5.5e-21 74.3 0.0 1.1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDN98066.1 - 1.7e-20 72.2 0.1 4.1e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDN98066.1 - 3.8e-16 59.8 0.0 1.7e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN98066.1 - 2.1e-08 34.0 1.2 3.9e-06 26.6 0.7 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDN98066.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EDN98067.1 - 5.3e-42 143.2 0.0 6.4e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EDN98068.1 - 2.4e-22 78.6 0.1 4.4e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EDN98068.1 - 0.064 13.3 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 UBX domain Ribosomal_L36e PF01158.13 EDN98069.1 - 1.8e-40 136.8 4.9 2.1e-40 136.6 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EDN98069.1 - 0.023 13.8 0.1 0.026 13.6 0.0 1.0 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 EDN98069.1 - 0.13 12.0 0.6 0.16 11.7 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 peroxidase PF00141.18 EDN98071.1 - 5.1e-51 173.3 0.0 8.3e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_17 PF00332.13 EDN98073.1 - 2.1e-14 53.2 1.0 2.9e-14 52.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 COX14 PF14880.1 EDN98074.1 - 1.4e-19 69.4 0.6 1.4e-19 69.4 0.4 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1180 PF06679.7 EDN98074.1 - 0.017 15.0 0.1 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2458 PF10454.4 EDN98075.1 - 1.7e-23 83.1 0.0 1.7e-23 83.1 0.0 2.6 2 2 1 3 3 3 1 Protein of unknown function (DUF2458) Aldo_ket_red PF00248.16 EDN98078.1 - 2.8e-69 233.0 0.0 3.2e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 EDN98079.1 - 1.5e-37 128.5 1.5 2.5e-37 127.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDN98079.1 - 0.12 12.3 3.1 0.23 11.4 2.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Glyco_hydro_76 PF03663.9 EDN98080.1 - 1.7e-43 149.4 13.9 3.2e-42 145.2 9.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_47 PF01532.15 EDN98080.1 - 0.00052 18.8 0.0 0.61 8.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 EDN98080.1 - 0.00088 18.3 0.1 0.91 8.5 0.0 2.9 1 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EDN98080.1 - 0.02 14.2 0.0 1.3 8.2 0.0 2.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus APOC4 PF15119.1 EDN98080.1 - 0.03 14.2 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C4 GPI-anchored PF10342.4 EDN98081.1 - 8.7e-18 64.5 6.2 8.7e-18 64.5 4.3 4.3 4 0 0 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2456 PF10445.4 EDN98081.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) GMC_oxred_N PF00732.14 EDN98082.1 - 1.6e-59 201.5 0.0 2.4e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN98082.1 - 3e-34 118.3 1.0 7.3e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EDN98082.1 - 2.7e-05 23.2 0.1 0.00045 19.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN98082.1 - 0.00097 18.1 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN98082.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN98082.1 - 0.011 14.5 0.4 0.061 12.1 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EDN98082.1 - 0.011 14.7 0.2 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EDN98082.1 - 0.057 11.8 0.1 0.26 9.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein PRKCSH-like PF12999.2 EDN98088.1 - 6.2e-40 136.6 14.0 4.9e-21 75.0 2.3 3.6 2 1 1 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EDN98088.1 - 1.2e-31 109.2 1.1 1.2e-31 109.2 0.8 2.3 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EDN98088.1 - 1.1e-09 39.0 1.2 1.1e-09 39.0 0.8 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EDN98088.1 - 2.3 8.2 13.2 0.055 13.3 1.4 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4090 PF13319.1 EDN98088.1 - 3.2 7.7 6.9 7.9 6.5 0.8 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4090) V_ATPase_I PF01496.14 EDN98088.1 - 5.5 4.7 9.0 7.8 4.2 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rtf2 PF04641.7 EDN98089.1 - 6.2e-57 192.7 1.8 9.2e-57 192.1 1.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EDN98089.1 - 4.2e-06 26.1 0.1 0.0069 15.8 0.1 2.6 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN98089.1 - 0.00038 20.1 0.1 0.0012 18.5 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EDN98089.1 - 0.08 12.6 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FAT PF02259.18 EDN98090.1 - 2.8e-131 437.6 4.1 7.3e-131 436.3 2.9 1.8 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 EDN98090.1 - 1.1e-63 213.8 3.7 9.7e-61 204.3 0.2 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EDN98090.1 - 1.5e-60 204.6 0.3 2.8e-60 203.6 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EDN98090.1 - 7.9e-44 147.8 0.9 4.7e-43 145.3 0.1 2.9 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EDN98090.1 - 2.7e-19 69.2 4.4 0.0019 18.4 0.0 8.2 4 2 3 8 8 8 5 HEAT repeats HEAT PF02985.17 EDN98090.1 - 3.8e-14 51.4 16.1 0.011 15.7 0.0 11.1 12 0 0 12 12 10 2 HEAT repeat HEAT_EZ PF13513.1 EDN98090.1 - 5.3e-14 52.2 6.0 3.4e-05 24.1 0.0 10.1 7 2 2 9 9 9 2 HEAT-like repeat FATC PF02260.15 EDN98090.1 - 3.6e-13 48.6 0.1 8e-13 47.5 0.1 1.6 1 0 0 1 1 1 1 FATC domain Adaptin_N PF01602.15 EDN98090.1 - 3.8e-06 25.5 6.2 0.001 17.5 0.2 4.1 3 2 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EDN98090.1 - 1e-05 25.8 0.2 67 3.9 0.0 7.3 6 1 2 8 8 7 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDN98090.1 - 0.00017 21.0 0.3 0.2 11.0 0.0 4.8 4 1 0 4 4 4 1 CLASP N terminal UME PF08064.8 EDN98090.1 - 0.00034 20.5 3.7 0.78 9.7 0.1 5.7 5 1 0 5 5 5 1 UME (NUC010) domain Apc3 PF12895.2 EDN98090.1 - 0.0088 16.1 2.7 2.2 8.4 0.0 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDN98090.1 - 0.017 14.8 2.1 2.5 8.0 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PmbA_TldD PF01523.11 EDN98090.1 - 0.16 11.2 0.0 0.43 9.7 0.0 1.6 2 0 0 2 2 2 0 Putative modulator of DNA gyrase TPR_14 PF13428.1 EDN98090.1 - 0.34 11.6 3.4 17 6.3 0.1 4.4 2 1 0 3 3 2 0 Tetratricopeptide repeat DnaJ PF00226.26 EDN98092.1 - 1.1e-21 76.2 1.8 1.1e-21 76.2 1.3 2.5 3 0 0 3 3 3 1 DnaJ domain DUF3500 PF12006.3 EDN98092.1 - 0.031 13.2 0.3 0.055 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Pup PF05639.6 EDN98092.1 - 0.3 11.6 0.2 0.3 11.6 0.1 2.6 2 1 0 2 2 2 0 Pup-like protein MFS_1 PF07690.11 EDN98093.1 - 6.5e-15 54.7 57.8 3.9e-13 48.8 39.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN98093.1 - 1.4e-07 30.1 29.1 1.8e-07 29.7 20.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ApbA PF02558.11 EDN98094.1 - 4.9e-29 100.7 0.0 6.8e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDN98094.1 - 1.1e-23 83.5 0.0 2.1e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Saccharop_dh PF03435.13 EDN98094.1 - 0.017 14.0 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DAO PF01266.19 EDN98094.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase zf-CCHC PF00098.18 EDN98096.1 - 0.0045 16.8 7.3 0.0076 16.1 5.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Glyco_tran_WecB PF03808.8 EDN98096.1 - 0.052 12.9 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF2681 PF10883.3 EDN98096.1 - 0.16 12.1 3.1 0.28 11.4 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sugar_tr PF00083.19 EDN98097.1 - 4.7e-31 107.8 9.0 5.8e-31 107.5 6.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN98097.1 - 2.1e-10 39.8 14.7 2.1e-10 39.8 10.2 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 EDN98099.1 - 9.1e-26 91.0 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN98099.1 - 1.8e-19 70.2 0.1 2.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN98099.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Fiji_64_capsid PF05880.6 EDN98099.1 - 0.16 10.2 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein IBR PF01485.16 EDN98100.1 - 5.7e-14 51.7 43.9 2.9e-08 33.4 7.2 3.4 3 0 0 3 3 3 3 IBR domain zf-piccolo PF05715.8 EDN98100.1 - 0.64 10.0 19.2 0.084 12.8 1.0 3.6 2 1 1 3 3 3 0 Piccolo Zn-finger DUF676 PF05057.9 EDN98101.1 - 1.7e-40 138.6 0.1 3.9e-26 91.7 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF4066 PF13278.1 EDN98102.1 - 2e-22 79.2 0.0 2.9e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EDN98102.1 - 2.9e-09 36.5 0.0 4.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Bac_rhamnosid PF05592.6 EDN98107.1 - 1.6e-11 43.1 0.1 9e-06 24.1 0.1 3.2 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EDN98107.1 - 0.00026 19.8 0.5 0.00059 18.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF608 TRM PF02005.11 EDN98108.1 - 2.1e-106 356.0 0.0 2e-91 306.7 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EDN98108.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.4 EDN98108.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_3 PF01596.12 EDN98108.1 - 0.022 13.7 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EDN98108.1 - 0.038 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BRF1 PF07741.8 EDN98108.1 - 9.1 6.5 9.4 0.66 10.2 3.1 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ank_2 PF12796.2 EDN98109.1 - 4.2e-91 299.4 17.6 1.4e-15 57.4 0.1 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN98109.1 - 1.9e-54 181.1 6.2 4.1e-10 39.8 0.0 10.5 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.25 EDN98109.1 - 1.3e-51 169.9 26.9 6.8e-06 25.6 0.0 15.0 15 0 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.1 EDN98109.1 - 2.3e-50 163.5 8.6 8e-06 25.6 0.0 14.5 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 EDN98109.1 - 1.5e-38 129.9 13.1 3.5e-05 23.9 0.2 11.8 2 2 11 13 13 13 9 Ankyrin repeats (many copies) NACHT PF05729.7 EDN98109.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EDN98109.1 - 1.3e-06 28.5 0.0 4.4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN98109.1 - 0.00025 21.1 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDN98109.1 - 0.0096 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EDN98109.1 - 0.011 16.5 0.0 0.047 14.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF3447 PF11929.3 EDN98109.1 - 0.012 15.3 0.0 0.094 12.5 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3447) RNA_helicase PF00910.17 EDN98109.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDN98109.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EDN98109.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.4 EDN98109.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNARE PF05739.14 EDN98110.1 - 1.1e-09 37.7 6.5 1.1e-09 37.7 4.5 2.4 3 0 0 3 3 3 1 SNARE domain V-SNARE PF05008.10 EDN98110.1 - 0.012 15.7 0.9 0.012 15.7 0.6 3.5 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus ODV-E18 PF10717.4 EDN98110.1 - 0.038 13.4 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 7TM-7TMR_HD PF07698.6 EDN98110.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF2562 PF10814.3 EDN98110.1 - 0.13 12.1 3.5 0.076 12.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) Baculo_PEP_C PF04513.7 EDN98110.1 - 0.28 10.9 11.8 2.5 7.9 2.6 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EDN98110.1 - 0.82 8.2 14.9 0.018 13.6 3.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF334 PF03904.8 EDN98110.1 - 1.8 7.8 12.2 0.16 11.2 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF334) Atg31 PF09795.4 EDN98111.1 - 0.0008 19.1 0.1 0.25 11.0 0.0 2.5 2 1 0 2 2 2 2 Autophagy-related protein 31 Asp PF00026.18 EDN98112.1 - 2.3e-68 230.7 7.8 3e-68 230.4 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN98112.1 - 4.4e-10 39.7 1.0 1.9e-09 37.6 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDN98112.1 - 6e-06 25.9 0.0 1.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDN98112.1 - 0.0015 18.9 1.6 3.5 8.1 0.4 3.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EDN98112.1 - 0.0047 16.7 0.4 0.99 9.2 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease PriCT_1 PF08708.6 EDN98113.1 - 0.092 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) tRNA-synt_1 PF00133.17 EDN98114.1 - 1.1e-161 538.8 0.0 1.5e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDN98114.1 - 9.9e-22 77.3 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDN98114.1 - 1.4e-21 76.6 0.1 1.4e-12 47.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EDN98114.1 - 1.9e-06 27.3 5.1 3.9e-06 26.3 3.5 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EDN98114.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EDN98114.1 - 0.12 11.1 0.0 6.2 5.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) HET PF06985.6 EDN98116.1 - 2.9e-21 76.0 4.3 1.8e-19 70.3 3.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EDN98117.1 - 4.3e-11 42.1 8.3 7.7e-11 41.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EDN98117.1 - 1.8e-08 33.0 10.8 0.0012 18.0 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EDN98117.1 - 4.2e-06 26.1 5.7 0.016 15.0 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EDN98117.1 - 1.5e-05 25.0 7.9 0.063 13.4 0.3 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 EDN98117.1 - 6.4e-05 22.4 9.1 0.00059 19.4 1.9 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EDN98117.1 - 1.4 8.4 9.3 7.1 6.1 0.4 3.5 3 0 0 3 3 3 0 EF hand C1_3 PF07649.7 EDN98117.1 - 2.7 8.1 5.8 5.3 7.1 4.0 1.5 1 0 0 1 1 1 0 C1-like domain Kinesin PF00225.18 EDN98118.1 - 1.2e-107 359.5 0.9 2.7e-107 358.3 0.6 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EDN98118.1 - 3.4e-07 30.5 0.5 3.4e-07 30.5 0.3 4.9 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding UPF0183 PF03676.9 EDN98119.1 - 1.1e-42 146.0 0.0 9.7e-28 96.8 0.0 4.2 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Tombus_movement PF05318.7 EDN98121.1 - 0.55 10.8 6.8 1.3 9.6 0.1 2.5 3 0 0 3 3 3 0 Tombusvirus movement protein Gypsy PF07253.6 EDN98122.1 - 0.11 10.7 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein FAD_binding_7 PF03441.9 EDN98126.1 - 0.048 12.8 0.0 0.049 12.8 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase MDFI PF15316.1 EDN98127.1 - 0.017 15.0 0.1 0.02 14.8 0.1 1.0 1 0 0 1 1 1 0 MyoD family inhibitor Tom37_C PF11801.3 EDN98128.1 - 3.8e-43 147.2 0.0 7.2e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EDN98128.1 - 2.6e-28 98.0 0.0 3.6e-27 94.4 0.0 2.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EDN98128.1 - 0.0067 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_4 PF07993.7 EDN98129.1 - 8.1e-11 41.3 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EDN98129.1 - 6.3e-10 39.1 0.0 1.5e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EDN98129.1 - 2.5e-08 32.7 0.0 4.2e-06 25.4 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Unstab_antitox PF09720.5 EDN98129.1 - 0.056 13.1 0.1 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Putative addiction module component Carn_acyltransf PF00755.15 EDN98130.1 - 1.8e-06 26.3 0.0 3.9e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pyr_redox_2 PF07992.9 EDN98131.1 - 2.1e-26 93.0 0.0 3.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN98131.1 - 7.6e-11 42.2 0.0 3.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN98131.1 - 0.00037 20.6 0.0 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN98131.1 - 2.2 8.3 5.8 14 5.7 0.0 3.6 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain CENP-F_leu_zip PF10473.4 EDN98132.1 - 0.005 16.7 0.3 0.073 12.9 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DDE_1 PF03184.14 EDN98133.1 - 1.1e-15 57.3 0.0 1.2e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PH_8 PF15409.1 EDN98133.1 - 0.058 13.4 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain TrkH PF02386.11 EDN98134.1 - 5.8e-85 284.9 6.8 1.3e-82 277.2 3.2 2.8 2 1 0 2 2 2 2 Cation transport protein Rad4 PF03835.10 EDN98135.1 - 1.1e-15 57.2 3.5 1.1e-15 57.2 2.4 1.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EDN98135.1 - 4.7e-05 23.5 1.0 0.00015 21.9 0.7 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pex14_N PF04695.8 EDN98135.1 - 8.1 6.4 14.1 3.8 7.5 6.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 EDN98137.1 - 7.2e-11 41.5 12.1 0.019 14.8 0.0 8.5 11 0 0 11 11 11 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EDN98137.1 - 1.7e-06 27.7 0.4 0.023 14.1 0.2 4.0 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 EDN98137.1 - 0.037 13.5 0.1 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 EDN98137.1 - 0.1 10.8 0.2 1.1 7.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) p450 PF00067.17 EDN98140.1 - 3.6e-21 75.2 0.0 4.5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S5 PF00333.15 EDN98143.1 - 9.5e-29 98.9 2.4 1.7e-28 98.1 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDN98143.1 - 1.6e-20 72.1 0.0 3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Fungal_trans_2 PF11951.3 EDN98144.1 - 1.1e-08 34.1 3.9 5.6e-08 31.7 2.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN98144.1 - 6.7e-08 32.3 8.6 6.7e-08 32.3 5.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_7 PF12914.2 EDN98144.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain of SH3b2 type Hexokinase_1 PF00349.16 EDN98144.1 - 0.13 11.5 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Hexokinase Uds1 PF15456.1 EDN98151.1 - 0.0036 17.2 4.2 0.0062 16.5 2.9 1.3 1 0 0 1 1 1 1 Up-regulated During Septation DUF3678 PF12435.3 EDN98154.1 - 0.0024 17.3 0.1 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) FKBP_C PF00254.23 EDN98155.1 - 6.6e-30 102.9 0.0 9.8e-30 102.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MT0933_antitox PF14013.1 EDN98155.1 - 0.013 15.6 3.6 0.028 14.5 2.5 1.6 1 0 0 1 1 1 0 MT0933-like antitoxin protein HCV_NS4a PF01006.15 EDN98157.1 - 0.033 13.7 0.8 0.08 12.4 0.6 1.7 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF613 PF04764.7 EDN98159.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF613) zf-Apc11 PF12861.2 EDN98161.1 - 5.6e-30 103.0 10.8 3.2e-27 94.2 7.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EDN98161.1 - 3.8e-19 68.5 7.3 4.6e-17 61.8 2.0 2.0 1 1 1 2 2 2 2 RING-H2 zinc finger zf-HIT PF04438.11 EDN98161.1 - 0.029 14.0 1.0 0.029 14.0 0.7 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING_2 PF13639.1 EDN98161.1 - 0.032 14.0 0.3 0.032 14.0 0.2 2.8 2 1 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.1 EDN98161.1 - 0.07 12.7 8.7 0.41 10.2 0.2 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EDN98161.1 - 0.24 11.0 11.0 1.9e+02 1.8 7.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 EDN98161.1 - 0.71 10.0 7.3 0.25 11.5 1.3 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Opy2 PF09463.5 EDN98161.1 - 0.84 9.7 10.0 5.7 7.1 0.2 2.3 2 0 0 2 2 2 0 Opy2 protein RecR PF02132.10 EDN98161.1 - 0.94 8.9 7.3 0.74 9.2 0.2 2.9 3 0 0 3 3 3 0 RecR protein zf-RING_5 PF14634.1 EDN98161.1 - 1.6 8.4 9.5 2.4 7.9 0.2 3.0 2 1 0 2 2 2 0 zinc-RING finger domain DZR PF12773.2 EDN98161.1 - 2.6 7.9 9.4 76 3.2 6.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon Rhodanese PF00581.15 EDN98162.1 - 5.2e-18 65.4 0.0 9.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain APG6 PF04111.7 EDN98165.1 - 0.005 15.9 0.6 0.0054 15.8 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Cortex-I_coil PF09304.5 EDN98165.1 - 0.0088 16.0 4.7 0.016 15.2 3.2 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil CASP_C PF08172.7 EDN98165.1 - 0.014 14.4 0.7 0.017 14.1 0.5 1.2 1 0 0 1 1 1 0 CASP C terminal BicD PF09730.4 EDN98165.1 - 0.017 13.4 0.9 0.022 13.1 0.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D BBP1_C PF15272.1 EDN98165.1 - 0.022 14.2 0.8 0.028 13.9 0.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Shugoshin_N PF07558.6 EDN98165.1 - 0.066 12.9 0.1 0.066 12.9 0.0 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EDN98165.1 - 0.6 9.6 8.1 2.9 7.4 1.0 2.9 1 1 2 3 3 3 0 Septum formation initiator RVT_1 PF00078.22 EDN98166.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EDN98167.1 - 1.7e-34 119.1 36.3 3e-26 91.9 7.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN98167.1 - 2.9e-14 52.5 7.5 2.9e-14 52.5 5.2 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.20 EDN98170.1 - 1.2e-36 126.2 0.0 4.5e-35 121.0 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN98170.1 - 9e-14 51.1 0.0 1.9e-07 30.4 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EDN98170.1 - 0.003 16.6 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN98170.1 - 0.0057 16.4 1.4 0.0099 15.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN98170.1 - 0.0086 15.4 0.0 0.069 12.4 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EDN98170.1 - 0.038 12.9 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like YtxH PF12732.2 EDN98172.1 - 0.015 15.6 3.0 0.17 12.2 0.0 3.1 2 2 0 2 2 2 0 YtxH-like protein Oxysterol_BP PF01237.13 EDN98172.1 - 0.028 12.9 0.5 0.047 12.1 0.3 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein Sec34 PF04136.10 EDN98172.1 - 0.03 14.0 2.7 0.56 9.9 0.1 2.5 2 0 0 2 2 2 0 Sec34-like family CENP-F_leu_zip PF10473.4 EDN98172.1 - 0.033 14.0 0.9 0.033 14.0 0.6 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Enkurin PF13864.1 EDN98172.1 - 0.3 11.3 6.2 3.9 7.7 0.0 3.7 4 0 0 4 4 4 0 Calmodulin-binding DUF4407 PF14362.1 EDN98172.1 - 4.3 6.1 19.4 86 1.9 13.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.15 EDN98172.1 - 9.5 5.2 21.6 0.4 9.7 2.1 3.1 3 0 0 3 3 3 0 Tropomyosin DUF3571 PF12095.3 EDN98173.1 - 0.13 12.5 1.0 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF718 PF05336.8 EDN98174.1 - 3.7e-15 55.6 0.3 4.4e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Ribosomal_L37e PF01907.14 EDN98176.1 - 9.2e-27 92.6 11.3 1.6e-26 91.8 7.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EDN98176.1 - 0.0057 16.4 1.1 0.0093 15.7 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EDN98176.1 - 0.89 9.1 4.0 18 4.9 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S14 PF00253.16 EDN98176.1 - 9.4 5.7 10.5 9 5.7 0.4 2.7 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF221 PF02714.10 EDN98177.1 - 2.1e-106 355.4 26.3 2.1e-106 355.4 18.3 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN98177.1 - 1.2e-41 141.9 0.7 1.2e-41 141.9 0.5 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDN98177.1 - 4.7e-21 74.4 0.0 1.3e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN98177.1 - 5.1e-09 36.5 6.5 0.0031 17.9 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) ANAPC15 PF15243.1 EDN98177.1 - 4.3 7.4 8.9 0.092 12.8 0.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Cu-oxidase_3 PF07732.10 EDN98179.1 - 1.8e-38 130.8 4.5 1.8e-38 130.8 3.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN98179.1 - 1.9e-38 131.0 8.4 1e-37 128.6 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EDN98179.1 - 1.3e-34 119.4 2.0 3e-34 118.2 0.7 2.2 1 1 1 2 2 2 1 Multicopper oxidase Spc7 PF08317.6 EDN98181.1 - 0.048 12.3 12.8 0.088 11.4 8.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1675 PF07897.6 EDN98181.1 - 0.054 13.3 1.1 0.08 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4201 PF13870.1 EDN98181.1 - 0.082 12.3 14.3 0.22 10.9 4.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) GvpK PF05121.7 EDN98181.1 - 0.32 10.8 7.4 0.19 11.5 2.0 2.6 1 1 1 2 2 2 0 Gas vesicle protein K FlxA PF14282.1 EDN98181.1 - 0.33 10.9 7.1 0.97 9.4 0.4 2.6 2 0 0 2 2 2 0 FlxA-like protein Jnk-SapK_ap_N PF09744.4 EDN98181.1 - 0.34 10.9 12.9 0.1 12.5 2.4 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.14 EDN98181.1 - 0.56 9.7 14.5 1.1 8.7 10.0 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EDN98181.1 - 1.1 7.0 5.6 1.5 6.5 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 EDN98181.1 - 1.2 9.1 12.8 2.4 8.2 3.2 2.4 2 0 0 2 2 2 0 YlqD protein BLOC1_2 PF10046.4 EDN98181.1 - 1.5 9.0 9.8 0.13 12.3 1.6 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 EDN98181.1 - 2 8.2 18.3 2.3 7.9 3.2 2.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 EDN98181.1 - 2.5 7.2 15.2 0.59 9.2 5.9 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HlyD PF00529.15 EDN98181.1 - 3.2 6.9 10.6 8.4 5.5 7.4 1.6 1 1 0 1 1 1 0 HlyD family secretion protein DUF1664 PF07889.7 EDN98181.1 - 3.2 7.5 4.8 12 5.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EDN98181.1 - 3.5 5.9 10.3 6.5 5.0 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Mod_r PF07200.8 EDN98181.1 - 5.4 6.9 15.7 1.3 8.9 3.7 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EDN98181.1 - 6.5 6.3 20.3 18 4.8 13.1 2.1 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EDN98181.1 - 6.6 6.7 7.4 4.6 7.2 0.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) UPF0016 PF01169.14 EDN98182.1 - 3e-39 133.0 17.3 2.9e-20 72.1 6.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4614 PF15391.1 EDN98182.1 - 2.5 7.8 6.8 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Peptidase_S24 PF00717.18 EDN98184.1 - 8.8e-06 25.2 0.0 4e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EDN98184.1 - 5.4e-05 22.7 0.0 0.035 13.6 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CN_hydrolase PF00795.17 EDN98185.1 - 9e-26 90.3 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EDN98185.1 - 1.5e-23 82.9 0.0 4.1e-23 81.5 0.0 1.6 1 1 0 1 1 1 1 NAD synthase MIP PF00230.15 EDN98188.1 - 1.5e-50 171.7 14.6 2e-50 171.4 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.1 EDN98189.1 - 1.4e-13 50.3 5.7 2.3e-13 49.7 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EDN98189.1 - 2.4e-11 43.1 0.0 6.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EDN98189.1 - 4.2e-09 36.2 5.3 6.6e-09 35.6 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN98189.1 - 4.9e-09 36.1 3.2 9.6e-09 35.2 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN98189.1 - 1.4e-08 34.2 3.0 2.2e-08 33.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN98189.1 - 1.1e-07 31.4 3.0 1.6e-07 30.8 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN98189.1 - 3.2e-07 29.9 2.4 5e-07 29.3 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDN98189.1 - 0.0012 18.6 1.1 0.0023 17.7 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EDN98189.1 - 0.038 13.8 3.7 0.13 12.1 2.6 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EDN98189.1 - 0.1 12.5 2.1 0.26 11.2 1.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EDN98189.1 - 0.12 12.0 2.8 0.29 10.8 1.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EDN98189.1 - 0.13 12.3 3.5 0.26 11.3 2.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EDN98189.1 - 0.25 11.3 3.6 0.47 10.4 2.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EDN98189.1 - 0.28 10.7 2.5 0.52 9.9 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EDN98189.1 - 1.1 9.0 3.0 1.9 8.2 2.1 1.5 1 0 0 1 1 1 0 PHD-finger SHIPPO-rpt PF07004.7 EDN98189.1 - 2.3 9.2 8.7 14 6.8 0.2 4.4 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat DUF946 PF06101.6 EDN98190.1 - 8e-13 47.2 1.3 5e-12 44.5 0.3 2.0 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EDN98190.1 - 0.008 15.9 0.3 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) EIF_2_alpha PF07541.7 EDN98191.1 - 2.2e-37 127.2 0.0 4.3e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EDN98191.1 - 3.1e-11 43.2 0.4 9e-11 41.7 0.3 1.9 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 EDN98192.1 - 3.2e-40 135.8 0.0 1e-20 73.3 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EDN98192.1 - 1.6e-17 64.1 3.3 1.5e-16 60.9 2.3 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase DUF3568 PF12092.3 EDN98192.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Mito_carr PF00153.22 EDN98193.1 - 8.6e-59 195.2 0.1 3.2e-21 74.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein GMC_oxred_N PF00732.14 EDN98194.1 - 3.3e-21 75.7 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN98194.1 - 3.1e-19 69.7 0.1 5.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase EndoU_bacteria PF14436.1 EDN98194.1 - 0.089 12.6 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial EndoU nuclease Amidohydro_1 PF01979.15 EDN98195.1 - 1.1e-43 150.1 0.0 1.4e-43 149.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EDN98195.1 - 3.4e-06 26.5 0.7 0.00041 19.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EDN98195.1 - 0.00034 20.3 0.0 0.00094 18.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EDN98195.1 - 0.012 15.6 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase Pterin_4a PF01329.14 EDN98198.1 - 2.7e-25 87.9 2.0 8.2e-25 86.3 0.1 2.3 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase DGF-1_4 PF11024.3 EDN98198.1 - 0.094 13.1 4.2 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Caleosin PF05042.8 EDN98199.1 - 1.4e-55 187.5 0.0 1.7e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 EDN98199.1 - 0.0057 16.4 0.1 0.069 13.0 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EDN98199.1 - 0.06 12.6 0.3 9.7 5.7 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF2238 PF09997.4 EDN98199.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) AAA PF00004.24 EDN98200.1 - 9.2e-55 184.4 0.0 3e-41 140.7 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN98200.1 - 2.8e-07 30.6 2.1 0.019 14.9 0.7 4.1 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EDN98200.1 - 3.8e-07 29.4 0.0 3.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDN98200.1 - 2.2e-06 27.5 0.0 0.0087 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDN98200.1 - 5.5e-06 26.1 0.6 0.0059 16.3 0.0 3.5 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN98200.1 - 1.5e-05 24.6 0.0 0.048 13.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EDN98200.1 - 2.1e-05 24.6 0.0 0.053 13.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.1 EDN98200.1 - 2.5e-05 24.4 3.3 0.23 11.6 0.7 4.6 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EDN98200.1 - 6.2e-05 23.0 0.0 0.033 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDN98200.1 - 0.00024 21.8 0.3 2.2 9.1 0.0 3.5 3 2 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EDN98200.1 - 0.00026 20.4 2.7 11 5.3 0.1 4.5 2 2 2 4 4 4 0 AAA domain AAA_2 PF07724.9 EDN98200.1 - 0.0034 17.3 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EDN98200.1 - 0.0048 15.6 0.0 0.039 12.6 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EDN98200.1 - 0.014 14.3 0.0 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EDN98200.1 - 0.02 14.5 4.4 2.2 7.8 0.0 3.5 4 1 1 5 5 4 0 AAA domain Sigma54_activ_2 PF14532.1 EDN98200.1 - 0.021 14.8 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.10 EDN98200.1 - 0.027 13.1 0.0 0.067 11.8 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EDN98200.1 - 0.036 13.4 0.1 10 5.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDN98200.1 - 0.052 12.7 0.4 0.95 8.5 0.1 2.8 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDN98200.1 - 0.052 13.4 0.0 5.5 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EDN98200.1 - 0.096 12.3 1.5 3.4 7.3 0.2 3.5 3 1 1 4 4 4 0 NACHT domain ResIII PF04851.10 EDN98200.1 - 0.17 11.6 0.3 4.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Ras PF00071.17 EDN98202.1 - 5.4e-65 217.7 0.0 6.5e-65 217.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN98202.1 - 6.3e-19 68.6 0.0 9.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN98202.1 - 5.2e-13 48.6 0.1 7.5e-13 48.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN98202.1 - 3.9e-06 26.4 0.1 7.4e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN98202.1 - 4.6e-06 25.9 0.0 5.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN98202.1 - 0.0049 16.8 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDN98202.1 - 0.014 14.5 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EDN98202.1 - 0.072 12.2 0.0 0.2 10.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EDN98202.1 - 0.084 12.1 0.0 0.5 9.6 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EDN98202.1 - 0.11 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN98202.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain NCA2 PF08637.5 EDN98203.1 - 1.9e-88 296.1 0.0 3.4e-88 295.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 PBP1_TM PF14812.1 EDN98203.1 - 0.096 13.0 3.0 0.23 11.7 2.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPR_2 PF13041.1 EDN98204.1 - 0.00049 20.0 3.0 11 6.0 0.0 5.7 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 EDN98204.1 - 0.11 12.5 5.7 12 6.1 0.0 5.6 6 0 0 6 6 6 0 PPR repeat bZIP_1 PF00170.16 EDN98208.1 - 7e-09 35.5 8.1 1.6e-07 31.1 5.6 2.2 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 EDN98208.1 - 0.011 15.5 0.2 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) HALZ PF02183.13 EDN98208.1 - 0.024 14.3 0.1 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper tRNA_synt_1c_R2 PF04557.10 EDN98208.1 - 0.043 14.5 1.0 0.19 12.4 0.0 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PAT1 PF09770.4 EDN98208.1 - 0.12 10.5 18.4 0.14 10.3 12.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 dsrm PF00035.20 EDN98208.1 - 0.58 10.7 2.8 1 10.0 0.3 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif bZIP_2 PF07716.10 EDN98208.1 - 1.6 8.5 7.6 9.3 6.1 5.3 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.14 EDN98209.1 - 3e-51 174.0 0.0 1.3e-29 102.8 0.0 2.2 2 0 0 2 2 2 2 Actin YL1_C PF08265.6 EDN98210.1 - 3.1e-17 61.7 0.1 5.2e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain YrhK PF14145.1 EDN98211.1 - 0.11 12.1 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 YrhK-like protein Got1 PF04178.7 EDN98212.1 - 1.2e-06 28.6 0.7 1.3e-06 28.4 0.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3953 PF13129.1 EDN98212.1 - 0.57 9.8 7.0 0.27 10.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Longin PF13774.1 EDN98213.1 - 1.3e-15 56.7 0.0 2.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDN98213.1 - 1.8e-14 53.0 0.4 3.1e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin RST PF12174.3 EDN98213.1 - 0.13 12.0 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Sec63 PF02889.11 EDN98214.1 - 4.6e-154 512.2 0.9 6.9e-97 324.4 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDN98214.1 - 1.1e-52 177.9 0.1 4.1e-28 97.9 0.1 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN98214.1 - 2e-15 56.4 0.0 6.3e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EDN98214.1 - 3.2e-15 56.4 0.0 5.1e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN98214.1 - 1.3e-08 35.0 0.0 0.0059 16.7 0.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EDN98214.1 - 6.2e-06 25.8 0.1 0.047 13.4 0.0 3.6 4 0 0 4 4 4 2 Part of AAA domain IstB_IS21 PF01695.12 EDN98214.1 - 0.013 14.9 0.7 9.4 5.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Collagen PF01391.13 EDN98215.1 - 2.2e-05 23.8 6.5 2.5e-05 23.7 4.5 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Acyl_transf_1 PF00698.16 EDN98216.1 - 4.7e-81 272.5 0.0 3.6e-80 269.6 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EDN98216.1 - 3.2e-38 129.8 0.0 6.7e-38 128.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EDN98216.1 - 9.1e-31 105.4 0.0 3.5e-30 103.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EDN98216.1 - 4.9e-22 78.1 0.0 3e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EDN98216.1 - 0.00048 19.3 1.3 0.0094 15.1 0.9 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase ketoacyl-synt PF00109.21 EDN98217.1 - 4.3e-20 72.2 0.0 8.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EDN98217.1 - 1.2e-17 64.4 0.0 7.1e-17 61.9 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EDN98217.1 - 1.7e-17 63.3 0.1 4.2e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EDN98217.1 - 1.9e-10 40.6 0.0 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDN98217.1 - 0.00037 20.4 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase IncA PF04156.9 EDN98217.1 - 0.0061 16.1 0.9 0.018 14.6 0.6 1.7 1 0 0 1 1 1 1 IncA protein SH3_9 PF14604.1 EDN98218.1 - 3.9e-19 67.9 2.9 1.7e-15 56.3 1.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EDN98218.1 - 1.6e-06 27.4 1.2 0.00041 19.7 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EDN98218.1 - 0.43 10.0 6.5 0.62 9.5 2.8 2.3 2 0 0 2 2 2 0 SH3 domain Profilin PF00235.14 EDN98219.1 - 1.9e-08 34.4 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Profilin CcmD PF04995.9 EDN98220.1 - 0.047 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PsbL PF02419.12 EDN98220.1 - 0.053 12.9 1.7 0.088 12.2 1.2 1.4 1 0 0 1 1 1 0 PsbL protein RSN1_TM PF13967.1 EDN98220.1 - 0.053 13.0 0.0 0.054 13.0 0.0 1.0 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport EphA2_TM PF14575.1 EDN98220.1 - 0.063 13.6 0.3 0.071 13.5 0.2 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PsbX PF06596.6 EDN98220.1 - 0.072 12.7 3.9 0.1 12.2 2.7 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Tetraspannin PF00335.15 EDN98220.1 - 0.086 12.0 0.0 0.088 12.0 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family SP_C-Propep PF08999.5 EDN98220.1 - 0.11 12.0 1.9 0.11 11.9 1.3 1.1 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide CbiN PF02553.10 EDN98220.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Cobalt transport protein component CbiN FtsL PF04999.8 EDN98220.1 - 0.12 12.1 0.1 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Cell division protein FtsL JTB PF05439.7 EDN98220.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) DUF4558 PF15104.1 EDN98223.1 - 2.3 8.2 5.7 0.58 10.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) ABC_membrane PF00664.18 EDN98225.1 - 6.3e-08 32.3 1.0 3.1e-06 26.8 0.1 3.9 2 1 2 4 4 4 2 ABC transporter transmembrane region DUF2207 PF09972.4 EDN98225.1 - 0.64 8.5 8.1 2.3 6.7 5.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_hydroxylase PF04116.8 EDN98226.1 - 4.5e-17 62.4 20.3 4.5e-17 62.4 14.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SE PF08491.5 EDN98227.1 - 3.3e-98 327.8 0.0 4.3e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EDN98227.1 - 3.9e-09 36.0 1.0 1.1e-07 31.3 0.7 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN98227.1 - 6.2e-09 35.2 0.2 1.1e-07 31.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN98227.1 - 1.5e-05 24.9 0.3 4.4e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EDN98227.1 - 2.6e-05 23.2 0.6 0.00014 20.8 0.4 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EDN98227.1 - 0.00025 20.2 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EDN98227.1 - 0.00041 19.3 0.0 0.085 11.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDN98227.1 - 0.0019 17.0 0.2 0.0029 16.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EDN98227.1 - 0.0028 17.1 0.1 0.0048 16.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EDN98227.1 - 0.0069 15.5 0.3 0.0094 15.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN98227.1 - 0.0085 15.9 0.1 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDN98227.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDN98227.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EDN98227.1 - 0.033 12.5 0.0 0.051 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EDN98227.1 - 0.04 14.3 0.1 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EDN98227.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EDN98227.1 - 0.21 11.4 0.4 0.45 10.3 0.2 1.5 1 0 0 1 1 1 0 ThiF family Phage_Gp19 PF09355.5 EDN98228.1 - 0.08 12.7 1.3 0.16 11.8 0.0 2.1 3 0 0 3 3 3 0 Phage protein Gp19/Gp15/Gp42 TT_ORF1 PF02956.9 EDN98230.1 - 0.05 12.0 2.1 0.069 11.5 1.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 ComFB PF10719.4 EDN98232.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Late competence development protein ComFB SMK-1 PF04802.10 EDN98233.1 - 3.4e-71 238.7 2.3 6.8e-71 237.7 1.6 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 FBD PF08387.5 EDN98233.1 - 0.84 9.1 3.1 16 5.0 0.1 3.0 3 0 0 3 3 3 0 FBD Glycos_transf_2 PF00535.21 EDN98234.1 - 9e-24 84.0 0.0 1.3e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDN98234.1 - 3.1e-09 36.9 0.0 1.1e-08 35.1 0.0 1.6 1 1 0 2 2 2 1 Glycosyltransferase like family 2 WD40 PF00400.27 EDN98235.1 - 3.3e-87 283.5 11.9 5.8e-16 57.6 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 EDN98235.1 - 8.3e-13 48.3 2.0 1.8e-06 27.6 0.2 2.5 1 1 1 2 2 2 2 NACHT domain PD40 PF07676.7 EDN98235.1 - 2.4e-05 23.9 4.1 39 4.0 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF1258 PF06869.7 EDN98235.1 - 0.0002 20.5 1.2 15 4.5 0.0 5.1 2 1 4 6 6 6 1 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 EDN98235.1 - 0.0008 17.8 0.1 0.7 8.1 0.0 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 EDN98235.1 - 0.012 14.3 0.0 1.3 7.5 0.0 2.8 2 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) AAA_19 PF13245.1 EDN98235.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain COG2 PF06148.6 EDN98235.1 - 0.09 12.6 0.4 0.25 11.1 0.3 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Mg_chelatase PF01078.16 EDN98235.1 - 0.094 11.8 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3435 PF11917.3 EDN98236.1 - 4.2e-67 226.7 0.0 6.2e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sugar_tr PF00083.19 EDN98237.1 - 4.4e-66 223.3 28.2 5e-66 223.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN98237.1 - 4.9e-10 38.6 40.3 2.4e-09 36.3 21.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN98237.1 - 0.57 8.5 35.7 0.0078 14.6 5.2 3.7 3 2 1 4 4 4 0 MFS/sugar transport protein Ras PF00071.17 EDN98238.1 - 1.2e-41 141.8 0.0 2.1e-39 134.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN98238.1 - 3.4e-17 63.0 0.0 5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN98238.1 - 3.8e-11 42.5 0.0 6.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN98238.1 - 0.00064 18.9 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN98238.1 - 0.0029 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDN98238.1 - 0.0064 15.7 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EDN98238.1 - 0.023 14.8 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDN98238.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN98238.1 - 0.046 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EDN98238.1 - 0.077 12.5 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN98238.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EDN98238.1 - 0.14 12.1 0.5 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EDN98238.1 - 0.15 11.8 0.1 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Dynamin family FMN_dh PF01070.13 EDN98239.1 - 5.8e-123 410.2 0.0 8.2e-123 409.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDN98239.1 - 7.3e-17 60.9 0.0 5.5e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDN98239.1 - 4.9e-08 32.2 0.0 8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDN98239.1 - 0.00021 20.3 0.0 0.0004 19.3 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EDN98239.1 - 0.0029 16.8 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EDN98239.1 - 0.024 13.8 0.7 0.51 9.5 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein Metallophos PF00149.23 EDN98240.1 - 3.9e-08 32.9 4.4 1.2e-07 31.3 3.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN98240.1 - 3e-07 30.4 0.1 6.1e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 EDN98240.1 - 0.65 9.5 3.9 3.2 7.2 0.8 2.2 1 1 0 2 2 2 0 Beta-lactamase superfamily domain Anoctamin PF04547.7 EDN98241.1 - 9e-119 397.0 2.3 1.1e-118 396.7 1.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HATPase_c PF02518.21 EDN98243.1 - 2e-24 85.4 0.0 4.5e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN98243.1 - 3.2e-21 75.4 0.0 6.5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDN98243.1 - 4.5e-10 39.3 0.0 1.2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EDN98243.1 - 1.9e-07 31.4 0.0 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EDN98243.1 - 2.2e-06 27.6 0.0 7.2e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EDN98243.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.1 EDN98243.1 - 0.00028 20.9 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 EDN98243.1 - 0.00078 19.2 0.0 0.0054 16.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EDN98243.1 - 0.004 17.6 0.0 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 GAF domain DUF719 PF05334.8 EDN98243.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PAS_3 PF08447.6 EDN98243.1 - 0.34 11.0 1.6 2.1 8.4 0.1 3.1 3 1 0 3 3 3 0 PAS fold FAD-oxidase_C PF02913.14 EDN98244.1 - 4.3e-29 101.5 0.0 8e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN98244.1 - 3.3e-28 97.9 0.0 6.6e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.2 EDN98244.1 - 9.4e-20 71.4 0.2 7.1e-19 68.5 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN98244.1 - 4.1e-14 52.6 0.0 1.7e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN98244.1 - 1.2e-08 34.8 0.0 4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EDN98244.1 - 0.0063 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Peptidase_S9 PF00326.16 EDN98244.1 - 0.076 12.2 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EDN98244.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain HET PF06985.6 EDN98247.1 - 1.1e-26 93.6 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Adhes-Ig_like PF09085.5 EDN98247.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like Ecm29 PF13001.2 EDN98247.1 - 0.13 10.6 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Proteasome stabiliser TLD PF07534.11 EDN98249.1 - 1.7e-30 105.8 0.0 2.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 TLD HIG_1_N PF04588.8 EDN98250.1 - 1.2e-18 66.5 0.4 2.1e-17 62.5 0.2 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EDN98250.1 - 0.051 13.4 0.6 0.13 12.2 0.4 1.6 1 1 0 1 1 1 0 MAS20 protein import receptor DUF1682 PF07946.9 EDN98250.1 - 0.44 9.3 8.9 0.6 8.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3395 PF11875.3 EDN98250.1 - 0.56 9.8 4.6 0.79 9.3 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) PALP PF00291.20 EDN98251.1 - 3.6e-60 203.7 2.0 4.8e-60 203.3 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EDN98251.1 - 4.3e-42 141.6 0.0 1.9e-22 78.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Amidohydro_3 PF07969.6 EDN98252.1 - 1.4e-38 133.1 0.0 7.7e-23 81.3 0.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EDN98252.1 - 0.0058 16.3 0.2 0.66 9.5 0.0 2.9 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 EDN98252.1 - 0.02 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase Memo PF01875.12 EDN98253.1 - 1.1e-72 244.2 0.0 1.3e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ABC_tran PF00005.22 EDN98254.1 - 4.5e-40 137.1 0.0 1.1e-17 64.5 0.0 3.5 2 1 1 3 3 3 3 ABC transporter ABC_membrane PF00664.18 EDN98254.1 - 3.2e-27 95.6 24.7 5.2e-25 88.3 6.5 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EDN98254.1 - 1.1e-11 45.3 0.2 0.099 12.5 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EDN98254.1 - 1.4e-09 38.2 0.1 0.00069 19.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EDN98254.1 - 6.6e-09 35.3 3.9 0.33 10.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EDN98254.1 - 8.1e-09 35.7 0.1 0.00031 20.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EDN98254.1 - 3.1e-07 30.9 0.1 0.02 15.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EDN98254.1 - 4e-07 29.4 0.1 0.0079 15.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDN98254.1 - 1.6e-06 28.0 0.0 0.075 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EDN98254.1 - 1.3e-05 24.4 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDN98254.1 - 1.4e-05 25.8 0.3 0.084 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDN98254.1 - 2.4e-05 24.2 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDN98254.1 - 0.00016 21.2 3.7 0.09 12.1 0.2 3.0 2 1 0 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 EDN98254.1 - 0.00018 21.3 0.5 1.1 9.2 0.2 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EDN98254.1 - 0.00031 21.1 0.2 1.1 9.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EDN98254.1 - 0.00037 20.7 0.1 0.57 10.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDN98254.1 - 0.00044 20.0 0.0 0.038 13.6 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EDN98254.1 - 0.00058 19.9 0.2 1 9.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase ATP-synt_ab PF00006.20 EDN98254.1 - 0.00081 18.9 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EDN98254.1 - 0.0011 19.2 0.6 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN98254.1 - 0.0015 17.9 1.2 1.1 8.5 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EDN98254.1 - 0.0023 17.8 0.0 0.15 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDN98254.1 - 0.0033 17.2 0.8 0.88 9.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EDN98254.1 - 0.005 16.5 0.2 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EDN98254.1 - 0.0058 16.4 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EDN98254.1 - 0.0064 16.2 0.7 1.8 8.3 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 EDN98254.1 - 0.011 15.1 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase NB-ARC PF00931.17 EDN98254.1 - 0.015 14.1 0.0 1.6 7.4 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 EDN98254.1 - 0.015 14.7 0.3 0.41 10.1 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EDN98254.1 - 0.021 14.4 2.1 1.4 8.5 0.1 3.3 3 0 0 3 3 3 0 NACHT domain DUF815 PF05673.8 EDN98254.1 - 0.028 13.3 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 EDN98254.1 - 0.031 13.1 0.1 1 8.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 EDN98254.1 - 0.037 12.6 0.1 2.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.13 EDN98254.1 - 0.047 13.2 0.1 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EDN98254.1 - 0.05 12.6 0.2 14 4.5 0.0 3.2 4 0 0 4 4 4 0 Septin KAP_NTPase PF07693.9 EDN98254.1 - 0.092 11.7 0.0 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_28 PF13521.1 EDN98254.1 - 0.12 12.3 0.2 5.1 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDN98254.1 - 0.12 12.0 3.9 11 5.7 0.0 3.4 4 0 0 4 4 4 0 NTPase AAA_24 PF13479.1 EDN98254.1 - 0.18 11.3 0.1 10 5.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDN98254.1 - 0.23 10.9 1.2 6.5 6.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EDN98254.1 - 0.23 10.5 0.1 21 4.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AA_permease PF00324.16 EDN98256.1 - 3.6e-133 444.3 50.1 6.3e-133 443.5 34.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN98256.1 - 1.7e-36 125.6 46.6 2.2e-36 125.3 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.15 EDN98256.1 - 3.6 7.2 9.5 0.19 11.3 0.8 3.1 2 1 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex p450 PF00067.17 EDN98258.1 - 7.2e-54 183.0 0.0 9.3e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DinB_2 PF12867.2 EDN98258.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 DinB superfamily DDE_1 PF03184.14 EDN98259.1 - 4.4e-50 169.8 0.1 2.5e-49 167.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN98259.1 - 8.9e-14 50.7 1.3 1.3e-12 47.0 0.1 2.6 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN98259.1 - 7.8e-13 48.3 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98259.1 - 2.2e-11 43.4 0.1 8.4e-11 41.5 0.0 2.2 2 0 0 2 2 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDN98259.1 - 0.0002 21.1 0.0 0.0006 19.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix NUMOD1 PF07453.8 EDN98259.1 - 0.0046 16.7 0.2 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 NUMOD1 domain HTH_24 PF13412.1 EDN98259.1 - 0.011 15.0 0.4 0.034 13.5 0.3 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 EDN98259.1 - 0.013 15.5 0.1 0.042 13.8 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain rve PF00665.21 EDN98259.1 - 0.015 15.3 0.1 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain HTH_23 PF13384.1 EDN98259.1 - 0.019 14.6 0.1 0.053 13.1 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_37 PF13744.1 EDN98259.1 - 0.039 13.7 2.5 0.039 13.7 0.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.7 EDN98259.1 - 0.093 12.2 0.1 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_AsnC-type PF13404.1 EDN98259.1 - 0.1 12.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pkinase PF00069.20 EDN98260.1 - 1.2e-05 24.6 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN98260.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN98260.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EDN98260.1 - 0.066 12.2 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.14 EDN98262.1 - 5.6e-21 74.9 0.0 8.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EDN98262.1 - 6.1e-07 29.7 0.0 0.00016 22.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN98262.1 - 1.2e-05 24.3 0.0 0.0011 17.9 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN98262.1 - 8.1e-05 22.5 0.1 0.00021 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EDN98262.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EDN98262.1 - 0.00067 19.5 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN98262.1 - 0.00072 18.1 0.0 0.0015 17.1 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EDN98262.1 - 0.0083 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDN98262.1 - 0.14 12.2 0.3 0.61 10.1 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN98262.1 - 0.21 10.6 0.4 0.32 10.0 0.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M24 PF00557.19 EDN98263.1 - 2.5e-42 144.8 0.0 3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EDN98263.1 - 0.00013 21.7 5.3 0.00013 21.7 3.7 2.1 2 0 0 2 2 2 1 MYND finger DUF2116 PF09889.4 EDN98263.1 - 0.035 13.9 0.8 0.083 12.7 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1065 PF06358.6 EDN98263.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) zf-HIT PF04438.11 EDN98263.1 - 0.67 9.6 3.8 1.8 8.2 2.6 1.8 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.9 EDN98264.1 - 9.1e-45 151.9 6.4 9.8e-45 151.8 4.4 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 EDN98265.1 - 6.5e-33 111.4 1.6 4.3e-10 39.0 0.2 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EDN98265.1 - 0.003 15.7 0.1 0.49 8.4 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 SOCS PF12610.3 EDN98266.1 - 1.2 9.5 3.4 2.1 8.7 2.4 1.4 1 0 0 1 1 1 0 Suppressor of cytokine signalling X PF00739.14 EDN98268.1 - 0.14 12.0 1.5 0.16 11.8 0.2 1.6 2 0 0 2 2 2 0 Trans-activation protein X Trypsin_2 PF13365.1 EDN98269.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2012 PF09430.5 EDN98269.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF3712 PF12505.3 EDN98271.1 - 2.5e-32 111.5 3.3 2.9e-31 108.0 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) DUF805 PF05656.9 EDN98271.1 - 0.0084 15.9 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF805) p450 PF00067.17 EDN98276.1 - 6.2e-53 179.9 0.0 9e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TatC PF00902.13 EDN98276.1 - 0.011 15.0 0.2 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Lentiviral_Tat PF02998.9 EDN98278.1 - 0.07 12.9 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Lentiviral Tat protein Zn_clus PF00172.13 EDN98286.1 - 3.2e-09 36.5 7.8 5.6e-09 35.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN98286.1 - 1.4e-07 30.6 0.1 2.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syja_N PF02383.13 EDN98290.1 - 5.4e-90 301.4 0.0 7.1e-90 300.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 EDN98291.1 - 3e-59 199.0 0.2 3.5e-59 198.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN98291.1 - 1.6e-19 70.5 0.1 2.8e-19 69.7 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN98291.1 - 6e-15 54.9 0.1 7.2e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN98291.1 - 5.1e-08 32.5 0.0 9.1e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN98291.1 - 7.6e-08 31.7 0.0 9.2e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN98291.1 - 4.2e-06 26.6 0.0 5.8e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDN98291.1 - 0.0067 16.5 0.1 0.61 10.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN98291.1 - 0.018 14.2 0.2 0.079 12.1 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN98291.1 - 0.039 13.9 0.2 0.1 12.5 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 EDN98291.1 - 0.062 12.5 0.1 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EDN98291.1 - 0.093 12.6 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Mitofilin PF09731.4 EDN98292.1 - 1.1e-161 539.4 11.3 1.4e-161 539.1 7.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 EDN98292.1 - 0.096 12.7 0.1 0.096 12.7 0.1 3.6 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC_tran PF00005.22 EDN98293.1 - 5.4e-45 153.0 11.2 1.6e-24 86.7 0.1 3.7 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EDN98293.1 - 7.3e-16 58.9 12.3 3.9e-06 27.0 4.6 4.5 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN98293.1 - 3.9e-12 45.8 3.2 0.0061 15.8 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDN98293.1 - 3.3e-09 37.6 3.3 0.0005 20.8 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDN98293.1 - 1.2e-08 34.3 1.0 0.00051 19.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDN98293.1 - 8.3e-07 28.9 1.1 0.017 15.1 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EDN98293.1 - 4.1e-06 26.5 0.6 0.05 13.3 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EDN98293.1 - 9e-06 26.1 0.9 0.19 12.2 0.0 3.0 2 1 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EDN98293.1 - 1.8e-05 24.8 1.8 0.093 12.8 0.0 3.7 4 2 0 4 4 3 2 AAA domain NACHT PF05729.7 EDN98293.1 - 4.4e-05 23.1 0.2 0.061 12.9 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EDN98293.1 - 6.6e-05 22.9 0.5 0.12 12.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran_2 PF12848.2 EDN98293.1 - 6.8e-05 22.6 5.7 6.8e-05 22.6 4.0 2.7 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EDN98293.1 - 0.00014 21.1 0.6 0.18 10.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EDN98293.1 - 0.00024 20.7 0.5 0.89 9.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDN98293.1 - 0.00028 20.7 5.7 0.22 11.3 0.5 3.3 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDN98293.1 - 0.00047 20.1 7.7 0.13 12.2 1.8 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EDN98293.1 - 0.00052 19.9 0.1 2 8.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 EDN98293.1 - 0.00067 19.8 0.0 0.027 14.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDN98293.1 - 0.0011 19.2 10.5 0.028 14.7 0.0 3.6 3 1 0 4 4 3 2 AAA domain ArgK PF03308.11 EDN98293.1 - 0.0012 17.6 1.6 0.077 11.7 0.1 2.6 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 EDN98293.1 - 0.0019 17.6 0.4 0.95 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN98293.1 - 0.0051 16.5 1.7 0.56 9.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDN98293.1 - 0.0063 16.6 0.2 0.59 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.1 EDN98293.1 - 0.015 14.3 13.2 0.019 14.0 1.4 3.6 4 1 0 4 4 4 0 AAA ATPase domain AAA_10 PF12846.2 EDN98293.1 - 0.017 14.5 8.4 1.8 7.9 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain NTPase_1 PF03266.10 EDN98293.1 - 0.018 14.7 2.4 2.1 7.9 0.1 3.1 3 0 0 3 3 3 0 NTPase KAP_NTPase PF07693.9 EDN98293.1 - 0.03 13.3 1.2 3 6.7 0.0 2.9 3 1 0 3 3 3 0 KAP family P-loop domain Dynamin_N PF00350.18 EDN98293.1 - 0.032 14.0 10.5 0.25 11.1 2.4 3.4 2 1 0 3 3 3 0 Dynamin family cobW PF02492.14 EDN98293.1 - 0.043 13.2 1.5 3.6 6.9 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EDN98293.1 - 0.049 13.3 0.6 0.64 9.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 EDN98293.1 - 0.14 11.7 0.7 2.2 7.7 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EDN98293.1 - 0.3 11.3 32.9 0.28 11.4 0.2 4.2 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 EDN98293.1 - 1.2 8.9 15.9 2.1 8.0 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function DUF87 Thymidylate_kin PF02223.12 EDN98293.1 - 1.2 8.4 6.8 4.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.17 EDN98293.1 - 3.5 6.3 9.7 6.9 5.4 0.0 3.5 4 0 0 4 4 4 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EDN98293.1 - 8.9 5.7 7.7 20 4.5 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family rve PF00665.21 EDN98295.1 - 2.9e-08 33.8 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN98295.1 - 8.7e-05 22.0 0.3 0.00026 20.5 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDN98295.1 - 0.032 13.9 0.2 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DnaB_bind PF10410.4 EDN98296.1 - 0.04 13.9 0.3 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Dicer_dimer PF03368.9 EDN98296.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Dicer dimerisation domain Glyco_hydro_18 PF00704.23 EDN98297.1 - 2.5e-11 43.6 0.2 1.3e-09 38.0 0.0 2.5 1 1 0 2 2 2 2 Glycosyl hydrolases family 18 V-ATPase_H_N PF03224.9 EDN98298.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H RNA_pol_3_Rpc31 PF11705.3 EDN98299.1 - 6.9e-61 206.1 15.2 7.7e-61 205.9 10.5 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cytomega_UL20A PF05984.7 EDN98299.1 - 0.044 13.9 4.7 0.091 12.9 3.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein FAD-oxidase_C PF02913.14 EDN98300.1 - 2.1e-53 181.1 0.4 3e-53 180.6 0.3 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN98300.1 - 2.6e-35 120.8 0.0 4.5e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EDN98300.1 - 0.11 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF963 PF06131.6 EDN98300.1 - 0.31 10.3 6.7 0.72 9.1 4.7 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ribosomal_S4e PF00900.15 EDN98302.1 - 8.3e-32 108.7 0.4 1.5e-31 107.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EDN98302.1 - 1.7e-17 62.9 2.7 3.2e-17 62.0 1.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EDN98302.1 - 3.5e-06 26.3 0.0 6.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EDN98302.1 - 0.0011 18.5 2.6 0.0028 17.3 0.4 2.8 2 0 0 2 2 2 1 KOW motif RdRP PF05183.7 EDN98303.1 - 8.2e-189 629.0 0.0 1.1e-188 628.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Semialdhyde_dhC PF02774.13 EDN98304.1 - 2e-41 141.9 0.0 2.6e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EDN98304.1 - 8.5e-30 103.5 0.0 2.4e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EDN98304.1 - 0.0039 17.0 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EDN98304.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2076 PF09849.4 EDN98305.1 - 8.9e-09 35.7 7.7 1e-08 35.5 5.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EDN98305.1 - 0.0002 21.1 5.4 0.00029 20.6 3.7 1.3 1 0 0 1 1 1 1 CHCH domain Sas10_Utp3 PF04000.10 EDN98306.1 - 4.1e-16 58.9 0.1 4.1e-16 58.9 0.1 2.5 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 EDN98306.1 - 1.6 6.2 13.9 1.8 6.1 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 EDN98306.1 - 7.1 6.3 15.0 11 5.7 10.4 1.4 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 EDN98306.1 - 10 5.2 12.5 13 4.8 8.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ApbA_C PF08546.6 EDN98308.1 - 1.1e-22 80.2 0.0 1.8e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDN98308.1 - 4.5e-16 58.6 0.0 1.8e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA dsDNA_bind PF01984.15 EDN98309.1 - 2.4e-36 123.9 6.3 2.8e-36 123.7 4.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DHHA1 PF02272.14 EDN98309.1 - 0.0047 16.6 2.9 0.0076 15.9 1.2 1.9 2 0 0 2 2 2 1 DHHA1 domain DUF4615 PF15393.1 EDN98309.1 - 0.016 15.4 0.8 0.022 15.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) CD99L2 PF12301.3 EDN98309.1 - 0.057 13.0 2.8 1.3 8.6 0.5 2.1 2 0 0 2 2 2 0 CD99 antigen like protein 2 Coq4 PF05019.8 EDN98310.1 - 7.5e-62 208.1 0.0 8.7e-62 207.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 EDN98311.1 - 1.2e-12 48.4 0.0 2.1e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 SET domain SecE PF00584.15 EDN98314.1 - 5.4e-14 51.4 0.0 6.2e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex UCR_Fe-S_N PF10399.4 EDN98314.1 - 0.0095 15.0 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal WD40 PF00400.27 EDN98315.1 - 1.9e-21 75.0 7.7 1.5e-08 34.1 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EDN98315.1 - 0.0029 17.8 0.5 9 6.7 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 EDN98315.1 - 0.0056 15.4 0.1 6.4 5.3 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EDN98315.1 - 0.068 12.8 0.0 0.068 12.8 0.0 2.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EDN98315.1 - 0.14 11.9 0.0 13 5.6 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Myb_DNA-binding PF00249.26 EDN98316.1 - 2.7e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN98316.1 - 0.00058 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ceramidase_alk PF04734.8 EDN98316.1 - 0.034 12.0 0.2 0.11 10.3 0.1 1.7 1 1 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase Tmemb_40 PF10160.4 EDN98317.1 - 0.032 13.4 1.0 0.04 13.1 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein Transgly_assoc PF04226.8 EDN98317.1 - 5.1 7.2 7.5 17 5.6 0.1 3.1 3 1 1 4 4 4 0 Transglycosylase associated protein UBX PF00789.15 EDN98318.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EDN98318.1 - 0.025 14.5 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like eIF3_subunit PF08597.5 EDN98318.1 - 5 6.6 8.6 2.7 7.4 4.2 1.7 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit SURF1 PF02104.10 EDN98319.1 - 8e-54 182.6 0.0 1.1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EDN98320.1 - 9.6e-79 265.5 19.6 2.5e-66 224.6 4.2 2.1 1 1 1 2 2 2 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 EDN98320.1 - 5.5e-08 32.8 0.0 9.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN98320.1 - 1.8e-06 27.8 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN98320.1 - 1.9e-05 24.6 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EDN98320.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NUP50 PF08911.6 EDN98320.1 - 0.018 15.4 0.1 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) ORC6 PF05460.8 EDN98320.1 - 0.09 11.8 0.5 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CMS1 PF14617.1 EDN98321.1 - 7.2e-112 372.5 3.0 8.3e-112 372.3 2.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EDN98321.1 - 2.2e-05 24.0 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.17 EDN98324.1 - 2.9e-09 36.4 0.0 6.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN98324.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hex_IIIa PF02455.11 EDN98324.1 - 1.4 7.5 9.4 2 6.9 6.5 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Macoilin PF09726.4 EDN98324.1 - 1.5 7.0 13.8 1.9 6.7 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 EDN98324.1 - 5.5 5.2 8.4 7.7 4.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MCLC PF05934.6 EDN98324.1 - 8 4.6 9.1 11 4.1 6.3 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Ras PF00071.17 EDN98325.1 - 3.3e-39 133.8 0.0 4e-38 130.3 0.0 1.9 1 1 1 2 2 2 1 Ras family Miro PF08477.8 EDN98325.1 - 3.8e-11 43.5 0.0 1.9e-10 41.2 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EDN98325.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EDN98325.1 - 0.058 12.6 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Peptidase_M24 PF00557.19 EDN98327.1 - 5.9e-39 133.7 0.0 8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAD_binding_8 PF08022.7 EDN98328.1 - 0.00063 19.5 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN98328.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Sulfotransfer_3 PF13469.1 EDN98333.1 - 6.4e-07 30.4 0.0 8.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.1 EDN98334.1 - 6.9e-46 156.7 5.4 5.7e-35 120.9 0.5 2.3 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EDN98334.1 - 2.7e-13 49.2 1.2 4.1e-12 45.3 0.2 2.2 1 1 0 2 2 2 2 Arylsulfotransferase (ASST) ICEA PF05315.6 EDN98335.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 ICEA Protein MFS_1 PF07690.11 EDN98336.1 - 2.2e-16 59.5 50.8 2.3e-16 59.4 28.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN98336.1 - 2.2e-08 33.1 0.7 2.2e-08 33.1 0.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter NRPS PF08415.5 EDN98336.1 - 0.027 14.2 0.4 0.088 12.5 0.3 1.9 1 0 0 1 1 1 0 Nonribosomal peptide synthase Phage_P2_GpU PF06995.6 EDN98338.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage P2 GpU Pyr_redox_3 PF13738.1 EDN98340.1 - 1.4e-19 70.9 0.0 2.3e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN98340.1 - 4.4e-12 44.9 0.0 1.4e-09 36.7 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN98340.1 - 1.9e-11 43.4 0.0 1.8e-09 37.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN98340.1 - 3.9e-09 36.6 0.0 2.5e-07 30.7 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN98340.1 - 2.6e-07 30.5 0.1 0.0011 18.7 0.0 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDN98340.1 - 3.5e-05 23.7 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDN98340.1 - 0.00071 18.1 0.0 2.1 6.7 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EDN98340.1 - 0.0025 16.9 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EDN98340.1 - 0.003 17.9 1.3 1.6 9.1 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN98340.1 - 0.0033 16.3 0.1 0.16 10.8 0.2 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EDN98340.1 - 0.015 15.5 0.1 4.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EDN98340.1 - 0.022 13.6 0.0 0.23 10.2 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EDN98340.1 - 0.11 11.3 0.0 0.28 10.0 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Lactonase PF10282.4 EDN98341.1 - 1.3e-69 234.9 0.1 1.6e-69 234.6 0.1 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1777 PF08648.7 EDN98343.1 - 0.18 11.5 11.3 0.19 11.4 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Agouti PF05039.7 EDN98343.1 - 0.2 12.0 5.4 0.2 12.0 3.7 1.1 1 0 0 1 1 1 0 Agouti protein Apis_Csd PF11671.3 EDN98343.1 - 0.83 9.4 7.2 0.93 9.2 5.0 1.0 1 0 0 1 1 1 0 Complementary sex determiner protein Cytomega_UL84 PF06284.6 EDN98343.1 - 0.91 7.8 3.8 0.97 7.7 2.6 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3915 PF13054.1 EDN98343.1 - 2.6 8.0 4.9 2.8 7.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.10 EDN98343.1 - 9.9 4.1 11.0 10 4.1 7.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Sterol-sensing PF12349.3 EDN98344.1 - 2.8e-39 134.0 1.9 8.6e-39 132.4 1.3 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EDN98344.1 - 0.00046 18.2 0.0 0.00069 17.6 0.0 1.2 1 0 0 1 1 1 1 Patched family adh_short PF00106.20 EDN98345.1 - 7.3e-20 71.5 0.0 9.4e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN98345.1 - 1.2e-07 31.6 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN98345.1 - 3.6e-07 30.2 0.0 4.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN98345.1 - 0.00021 21.0 0.4 0.00042 20.0 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EDN98345.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EDN98345.1 - 0.11 12.4 0.6 0.2 11.6 0.4 1.4 1 0 0 1 1 1 0 NADH(P)-binding SR-25 PF10500.4 EDN98346.1 - 0.042 13.3 14.2 0.045 13.2 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TALPID3 PF15324.1 EDN98346.1 - 0.1 9.9 7.8 0.11 9.7 5.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Tir_receptor_N PF07490.6 EDN98346.1 - 0.14 11.7 5.8 0.15 11.6 4.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus SSP160 PF06933.6 EDN98346.1 - 0.22 9.4 7.8 0.21 9.5 5.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4614 PF15391.1 EDN98346.1 - 1.4 8.6 9.7 1.5 8.5 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF515 PF04415.7 EDN98346.1 - 2.8 6.1 7.1 2.5 6.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) NST1 PF13945.1 EDN98346.1 - 4.5 7.2 6.6 4.7 7.2 4.6 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Pap_E4 PF02711.9 EDN98346.1 - 5 8.0 9.6 6.2 7.7 6.7 1.2 1 0 0 1 1 1 0 E4 protein Herpes_pp85 PF04637.7 EDN98346.1 - 6.2 5.0 6.8 6.8 4.8 4.7 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-3CxxC PF13695.1 EDN98347.1 - 2.4 8.4 9.3 1.4 9.1 4.0 2.2 1 1 1 2 2 2 0 Zinc-binding domain YL1_C PF08265.6 EDN98348.1 - 0.0098 15.4 1.2 0.021 14.3 0.8 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Usp PF00582.21 EDN98349.1 - 7.3 6.7 6.4 1.2e+02 2.8 4.5 2.0 1 1 0 1 1 1 0 Universal stress protein family Glyco_hydro_16 PF00722.16 EDN98351.1 - 1.1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ABC1 PF03109.11 EDN98352.1 - 7.7e-33 112.9 0.0 2.9e-32 111.1 0.0 2.1 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.4 EDN98353.1 - 1.7e-105 353.8 1.1 2.1e-105 353.5 0.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 cwf21 PF08312.7 EDN98353.1 - 0.032 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 cwf21 domain Metallophos PF00149.23 EDN98354.1 - 5e-37 127.2 0.0 7.7e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EDN98354.1 - 3.4e-28 97.5 2.2 2.5e-27 94.7 0.3 2.5 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EDN98354.1 - 4e-25 87.2 7.4 2.2e-18 65.6 1.7 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDN98354.1 - 1.3e-16 59.4 5.2 0.0001 21.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDN98354.1 - 6.1e-14 50.7 3.9 0.00052 19.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN98354.1 - 8.2e-08 31.8 1.1 0.0006 19.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN98354.1 - 3.7e-07 30.6 2.4 0.018 15.6 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN98354.1 - 0.00016 22.0 0.4 0.2 12.4 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN98354.1 - 0.00016 21.9 3.0 0.9 9.9 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN98354.1 - 0.0002 21.1 0.0 0.18 11.6 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN98354.1 - 0.00059 20.1 0.6 0.034 14.5 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN98354.1 - 0.014 15.3 2.6 0.043 13.7 0.5 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EDN98354.1 - 0.018 14.1 1.4 1.8 7.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EDN98354.1 - 0.021 14.6 3.6 2.9 7.8 0.3 2.6 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2683 PF10884.3 EDN98354.1 - 0.031 14.1 0.2 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) TPR_7 PF13176.1 EDN98354.1 - 0.045 13.5 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EDN98354.1 - 0.079 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Saccharop_dh PF03435.13 EDN98355.1 - 4.4e-129 430.8 0.0 5.2e-129 430.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EDN98355.1 - 2.5e-06 27.6 0.1 3.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EDN98355.1 - 5.6e-05 23.2 0.5 0.00013 21.9 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding IlvN PF07991.7 EDN98355.1 - 0.00094 18.5 0.3 0.011 15.0 0.0 2.6 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EDN98355.1 - 0.025 14.9 0.1 0.049 14.0 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EDN98355.1 - 0.034 14.1 0.3 0.062 13.3 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EDN98355.1 - 0.036 14.5 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DER1 PF04511.10 EDN98356.1 - 9.9e-24 83.9 0.2 1.1e-23 83.7 0.2 1.0 1 0 0 1 1 1 1 Der1-like family CN_hydrolase PF00795.17 EDN98357.1 - 9.1e-16 57.7 0.0 1.7e-15 56.8 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Type_III_YscX PF09474.5 EDN98358.1 - 0.078 12.9 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) TP53IP5 PF15331.1 EDN98363.1 - 0.057 13.3 0.3 0.084 12.7 0.2 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RVT_2 PF07727.9 EDN98366.1 - 1.5e-70 236.9 0.0 2.8e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN98366.1 - 2.4e-11 43.7 0.0 8.2e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN98366.1 - 1.9e-08 33.8 0.0 6.6e-08 32.0 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN98366.1 - 2.7e-05 23.9 0.4 6.1e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN98366.1 - 0.00036 20.0 0.6 0.00036 20.0 0.4 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN98366.1 - 0.0044 16.4 3.0 0.0044 16.4 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-Sec23_Sec24 PF04810.10 EDN98366.1 - 0.032 13.7 0.1 6.2 6.4 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Shugoshin_N PF07558.6 EDN98369.1 - 0.02 14.5 0.3 0.043 13.5 0.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region NTP_transf_5 PF14907.1 EDN98369.1 - 0.041 13.2 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase NYD-SP28_assoc PF14775.1 EDN98369.1 - 0.093 12.4 1.0 1.2 8.8 0.6 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain SBDS PF01172.13 EDN98371.1 - 0.012 15.3 0.2 0.014 15.1 0.1 1.0 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Septin PF00735.13 EDN98372.1 - 4.7e-124 412.9 0.4 4.7e-124 412.9 0.3 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDN98372.1 - 5.5e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EDN98372.1 - 3.3e-05 24.2 1.4 0.027 14.7 0.0 2.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EDN98372.1 - 8.6e-05 21.7 0.3 0.0007 18.8 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN98372.1 - 0.00014 21.3 0.0 0.002 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 EDN98372.1 - 0.00071 19.0 2.0 0.0032 16.9 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDN98372.1 - 0.0034 17.8 0.0 0.015 15.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EDN98372.1 - 0.0035 17.3 0.1 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EDN98372.1 - 0.0041 16.6 0.1 0.52 9.8 0.0 2.8 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 EDN98372.1 - 0.0046 16.3 0.1 0.049 13.0 0.0 2.6 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.1 EDN98372.1 - 0.0052 16.9 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 EDN98372.1 - 0.0066 15.5 0.0 0.0066 15.5 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.1 EDN98372.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EDN98372.1 - 0.025 14.2 0.6 0.3 10.7 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EDN98372.1 - 0.032 13.7 0.0 0.032 13.7 0.0 2.5 4 0 0 4 4 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EDN98372.1 - 0.045 13.5 8.3 0.64 9.8 0.0 3.9 4 1 0 4 4 3 0 Dynamin family RNA_helicase PF00910.17 EDN98372.1 - 0.099 12.8 0.7 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase YlqD PF11068.3 EDN98372.1 - 0.1 12.6 13.2 0.24 11.4 9.2 1.6 1 0 0 1 1 1 0 YlqD protein AAA_24 PF13479.1 EDN98372.1 - 0.1 12.1 0.8 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.10 EDN98372.1 - 0.12 11.5 8.4 0.3 10.2 5.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.6 EDN98372.1 - 0.3 10.8 2.9 0.47 10.2 1.1 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat IncA PF04156.9 EDN98372.1 - 0.57 9.7 10.6 1.3 8.6 7.4 1.6 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 EDN98372.1 - 0.99 8.5 8.3 1.8 7.7 5.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 EDN98372.1 - 2.1 8.0 7.0 4.1 7.1 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AA_permease PF00324.16 EDN98374.1 - 3.9e-71 239.8 23.5 3.2e-61 207.1 12.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDN98374.1 - 9e-19 67.2 26.1 1.5e-16 59.9 13.2 2.1 1 1 1 2 2 2 2 Amino acid permease F-box PF00646.28 EDN98375.1 - 0.00027 20.5 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN98375.1 - 0.0057 16.3 0.2 0.0057 16.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 EDN98376.1 - 6.1e-24 84.3 35.8 8.9e-24 83.8 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EDN98378.1 - 1.7e-30 105.9 42.5 1.7e-30 105.9 29.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN98378.1 - 1.6e-10 40.2 15.4 1.6e-10 40.2 10.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EDN98378.1 - 2.9e-06 25.7 8.6 4.6e-06 25.1 6.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF983 PF06170.7 EDN98378.1 - 4.9 7.3 8.8 0.4 10.8 0.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF983) BTB PF00651.26 EDN98379.1 - 0.0017 18.2 0.0 0.0082 16.1 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain PPR_2 PF13041.1 EDN98380.1 - 1.9e-19 69.3 0.2 0.0098 15.8 0.0 7.6 5 3 3 8 8 8 5 PPR repeat family PPR_3 PF13812.1 EDN98380.1 - 2.1e-19 68.1 8.1 0.00021 21.3 0.0 8.6 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.15 EDN98380.1 - 3.4e-05 23.5 15.5 0.78 9.8 0.0 8.1 9 0 0 9 9 9 1 PPR repeat Ftsk_gamma PF09397.5 EDN98380.1 - 0.032 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Ftsk gamma domain PPR_1 PF12854.2 EDN98380.1 - 4.6 6.7 0.0 4.6 6.7 0.0 5.2 8 0 0 8 8 8 0 PPR repeat LSM PF01423.17 EDN98381.1 - 1.1e-16 60.1 0.0 1.5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN98381.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain GRP PF07172.6 EDN98381.1 - 2.4 8.6 17.8 3.1 8.3 12.3 1.2 1 0 0 1 1 1 0 Glycine rich protein family DSPc PF00782.15 EDN98383.1 - 1.5e-10 40.7 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN98383.1 - 0.00025 20.4 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EDN98383.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EDN98383.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PTEN_C2 PF10409.4 EDN98383.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Cytochrome_cB PF11783.3 EDN98385.1 - 0.042 13.3 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial ZF-HD_dimer PF04770.7 EDN98385.1 - 0.16 12.0 1.4 0.32 11.0 1.0 1.5 1 0 0 1 1 1 0 ZF-HD protein dimerisation region Peptidase_M22 PF00814.20 EDN98389.1 - 2.8e-37 128.6 0.0 3.7e-36 124.9 0.0 2.3 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EDN98389.1 - 0.022 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein ABC2_membrane_3 PF12698.2 EDN98390.1 - 1.5 7.7 6.6 3.5 6.5 4.6 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Ank_2 PF12796.2 EDN98391.1 - 3e-78 258.2 7.9 1.7e-13 50.7 0.0 8.0 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EDN98391.1 - 1e-57 189.1 11.7 1.6e-06 27.6 0.0 15.8 16 1 0 16 16 16 13 Ankyrin repeat Ank_4 PF13637.1 EDN98391.1 - 2.6e-49 164.7 7.7 3.2e-06 27.4 0.0 13.6 5 4 9 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN98391.1 - 2.7e-41 138.6 13.0 2.1e-06 27.7 0.0 11.6 8 6 5 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN98391.1 - 1e-39 130.5 6.6 0.00062 19.7 0.0 15.6 16 0 0 16 16 16 8 Ankyrin repeat Tower PF09121.5 EDN98392.1 - 2.3 8.2 9.3 0.36 10.7 1.0 2.4 1 1 1 2 2 2 0 Tower Noelin-1 PF12308.3 EDN98393.1 - 0.00094 18.9 1.6 0.00094 18.9 1.1 2.2 2 1 1 3 3 3 1 Neurogenesis glycoprotein Spore_IV_A PF09547.5 EDN98393.1 - 0.012 14.3 2.2 0.018 13.7 1.5 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) CENP-F_leu_zip PF10473.4 EDN98393.1 - 0.047 13.5 17.3 0.048 13.5 3.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EDN98393.1 - 0.21 9.3 4.4 0.27 9.0 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EDN98393.1 - 0.39 9.7 13.2 0.66 8.9 9.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 EDN98393.1 - 0.47 9.6 3.6 0.22 10.7 0.9 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 EDN98393.1 - 6.1 6.4 17.0 66 3.0 11.9 2.1 1 1 0 1 1 1 0 IncA protein TMEM51 PF15345.1 EDN98394.1 - 0.09 12.4 1.8 0.16 11.6 1.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Transp_Tc5_C PF04236.10 EDN98395.1 - 0.012 15.8 1.1 0.017 15.3 0.7 1.4 1 1 0 1 1 1 0 Tc5 transposase C-terminal domain DUF2369 PF10179.4 EDN98395.1 - 0.025 13.7 1.8 0.037 13.1 1.2 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Meleagrin PF08189.6 EDN98395.1 - 0.077 12.4 1.1 0.078 12.4 0.1 1.5 2 0 0 2 2 2 0 Meleagrin/Cygnin family DUF1319 PF07028.6 EDN98396.1 - 0.052 13.7 2.6 0.13 12.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) bZIP_1 PF00170.16 EDN98396.1 - 0.077 12.9 3.8 0.19 11.7 2.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor Glyco_hydro_3 PF00933.16 EDN98397.1 - 5.6e-89 298.0 0.0 8.9e-89 297.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN98397.1 - 1.1e-56 191.9 2.7 2e-56 191.0 0.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN98397.1 - 9.6e-14 51.0 0.0 2.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain GP46 PF07409.7 EDN98398.1 - 0.018 14.3 0.5 0.14 11.4 0.0 1.9 1 1 1 2 2 2 0 Phage protein GP46 CwfJ_C_1 PF04677.10 EDN98399.1 - 9.6e-27 93.0 0.0 1.7e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDN98399.1 - 1.6e-25 89.3 0.3 3.1e-25 88.5 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 EDN98400.1 - 3.9e-42 143.0 0.0 4.4e-41 139.5 0.0 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.1 EDN98401.1 - 0.00057 20.1 0.8 0.036 14.3 0.0 3.7 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EDN98401.1 - 0.0026 17.6 4.5 0.07 13.2 0.0 5.3 6 1 1 7 7 7 1 HEAT repeat DNA_alkylation PF08713.6 EDN98401.1 - 0.0063 16.0 2.8 1.4 8.4 0.1 3.0 2 1 1 3 3 3 2 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.2 EDN98401.1 - 0.05 13.9 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region zf-DNL PF05180.7 EDN98402.1 - 1.2e-28 98.6 0.1 2e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EDN98402.1 - 0.017 14.6 0.4 0.029 13.8 0.3 1.3 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EDN98402.1 - 0.11 12.2 1.1 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDN98402.1 - 0.11 12.0 0.6 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EDN98402.1 - 0.12 12.1 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cullin PF00888.17 EDN98403.1 - 9.5e-134 447.1 4.0 1.5e-133 446.4 2.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDN98403.1 - 2e-26 91.6 1.9 5.7e-26 90.1 1.3 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Fungal_trans_2 PF11951.3 EDN98404.1 - 5.3e-25 87.8 4.3 7.4e-25 87.3 2.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN98404.1 - 1.3e-09 37.8 9.2 2e-09 37.1 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.15 EDN98405.1 - 3.8e-18 65.8 0.0 3.8e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EDN98405.1 - 2.4e-17 62.6 0.0 1.8e-16 59.8 0.0 2.3 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EDN98405.1 - 3.5e-09 36.8 0.0 2.8e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN98405.1 - 0.0015 18.3 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Amidase PF01425.16 EDN98406.1 - 7.1e-84 282.1 0.0 1.1e-83 281.5 0.0 1.3 1 1 0 1 1 1 1 Amidase Exo_endo_phos PF03372.18 EDN98408.1 - 1.9e-16 60.7 0.0 2.8e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EDN98409.1 - 5.8e-51 168.6 17.5 6e-13 48.1 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDN98409.1 - 6.2e-06 26.0 0.0 0.017 14.8 0.0 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EDN98409.1 - 0.00018 20.3 0.3 0.0046 15.7 0.0 2.4 2 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EDN98409.1 - 0.0015 16.7 0.1 0.0095 14.1 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDN98409.1 - 0.016 14.6 0.4 0.37 10.1 0.1 2.3 1 1 1 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.9 EDN98409.1 - 0.044 12.5 0.0 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.7 EDN98409.1 - 0.066 12.8 1.4 13 5.6 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SNF2_N PF00176.18 EDN98410.1 - 3e-32 111.6 0.0 3.1e-28 98.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN98410.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox_2 PF07992.9 EDN98411.1 - 1.3e-19 70.8 0.0 2.9e-19 69.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN98411.1 - 2.2e-09 37.5 0.1 3.2e-08 33.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN98411.1 - 0.013 15.2 0.1 7.8 6.2 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF4339 PF14237.1 EDN98415.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Mad3_BUB1_I PF08311.7 EDN98417.1 - 4.2e-42 142.9 0.0 8.3e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EDN98417.1 - 2.8e-15 56.1 0.0 5.2e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN98417.1 - 5.3e-06 25.6 0.0 1.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EDN98417.1 - 6.3e-05 22.7 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Cu_bind_like PF02298.12 EDN98419.1 - 0.16 11.7 1.5 0.56 10.0 1.0 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Zip PF02535.17 EDN98422.1 - 0.91 8.4 5.6 1.3 7.9 3.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter AP_endonuc_2 PF01261.19 EDN98424.1 - 6.8e-29 100.6 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SMN PF06003.7 EDN98424.1 - 9.3 5.2 11.8 0.11 11.5 1.2 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) RED_N PF07808.8 EDN98425.1 - 4.4e-11 42.4 5.9 4.4e-11 42.4 4.1 2.0 2 0 0 2 2 2 1 RED-like protein N-terminal region p450 PF00067.17 EDN98426.1 - 1.6e-24 86.2 0.1 1.4e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 IU_nuc_hydro PF01156.14 EDN98429.1 - 0.041 13.0 0.0 0.041 13.0 0.0 1.0 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.14 EDN98430.1 - 1.6e-53 181.9 0.0 1.9e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mago-bind PF09282.5 EDN98431.1 - 9.4e-13 47.4 3.6 1.8e-12 46.5 2.5 1.5 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 EDN98431.1 - 7.1 6.4 13.2 8.7 6.1 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UCR_UQCRX_QCR9 PF05365.7 EDN98432.1 - 3.5e-27 93.7 1.0 3.9e-27 93.6 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 EDN98433.1 - 3e-18 65.2 13.7 5.7e-18 64.4 9.5 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EDN98433.1 - 3.3e-06 26.7 0.4 7.4e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.14 EDN98433.1 - 0.014 14.7 2.1 0.029 13.6 1.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-H2C2_2 PF13465.1 EDN98434.1 - 0.11 12.8 0.9 0.5 10.7 0.7 2.2 1 0 0 1 1 1 0 Zinc-finger double domain DEAD PF00270.24 EDN98435.1 - 2.7e-07 30.2 0.0 6.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDT1 PF08839.6 EDN98435.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like SBP_bac_3 PF00497.15 EDN98435.1 - 0.008 15.4 0.1 0.44 9.7 0.0 2.9 2 1 1 3 3 3 1 Bacterial extracellular solute-binding proteins, family 3 Cut8_N PF14482.1 EDN98435.1 - 0.011 15.7 2.8 0.011 15.7 1.9 2.0 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Ribosomal_S4e PF00900.15 EDN98435.1 - 0.063 12.9 0.1 0.2 11.3 0.1 1.9 1 0 0 1 1 1 0 Ribosomal family S4e DUF1998 PF09369.5 EDN98436.1 - 1.8e-13 50.8 0.2 5.4e-13 49.3 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EDN98436.1 - 2.7e-09 36.7 0.0 8.4e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FeoC PF09012.5 EDN98438.1 - 0.0028 17.3 2.7 0.35 10.6 0.1 4.0 3 0 0 3 3 3 1 FeoC like transcriptional regulator SlyX PF04102.7 EDN98438.1 - 0.008 16.5 0.4 0.008 16.5 0.3 7.9 7 1 1 8 8 8 1 SlyX zf-C2H2_jaz PF12171.3 EDN98438.1 - 0.14 12.3 2.6 0.45 10.7 1.8 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Baculo_PEP_C PF04513.7 EDN98438.1 - 0.95 9.2 22.0 0.95 9.2 0.5 5.2 3 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 EDN98438.1 - 6.2 6.6 21.4 0.17 11.7 0.1 5.2 4 2 2 6 6 6 0 Protein of unknown function (DUF1515) Spc7 PF08317.6 EDN98440.1 - 0.00014 20.6 7.2 0.15 10.6 3.3 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Leu_zip PF15294.1 EDN98440.1 - 0.00029 20.0 4.1 0.00042 19.5 2.8 1.4 1 1 0 1 1 1 1 Leucine zipper ATG16 PF08614.6 EDN98440.1 - 0.0004 20.2 6.8 0.0069 16.2 1.8 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) HemX PF04375.9 EDN98440.1 - 0.00047 18.8 2.8 0.00047 18.8 1.9 1.5 2 0 0 2 2 2 1 HemX TBPIP PF07106.8 EDN98440.1 - 0.00065 19.2 7.9 0.56 9.7 0.0 2.8 2 1 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EDN98440.1 - 0.0011 18.8 2.6 1 9.3 0.2 2.8 2 1 0 2 2 2 2 bZIP transcription factor Tektin PF03148.9 EDN98440.1 - 0.0024 16.4 7.5 0.084 11.4 3.0 2.0 2 0 0 2 2 2 2 Tektin family ERM PF00769.14 EDN98440.1 - 0.0032 17.0 7.4 0.073 12.5 2.8 2.1 1 1 0 2 2 2 1 Ezrin/radixin/moesin family DUF641 PF04859.7 EDN98440.1 - 0.0033 17.1 2.6 0.045 13.4 0.9 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) GOLGA2L5 PF15070.1 EDN98440.1 - 0.0036 15.8 3.0 0.0042 15.6 2.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 SlyX PF04102.7 EDN98440.1 - 0.0036 17.6 5.4 0.013 15.8 0.4 3.3 2 2 2 4 4 4 1 SlyX DUF2353 PF09789.4 EDN98440.1 - 0.0039 16.5 3.6 0.0039 16.5 2.5 1.7 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) Lge1 PF11488.3 EDN98440.1 - 0.0072 16.4 4.4 0.051 13.7 0.9 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 Reo_sigmaC PF04582.7 EDN98440.1 - 0.01 15.0 1.5 0.021 13.9 0.8 1.6 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Med9 PF07544.8 EDN98440.1 - 0.013 15.2 10.5 0.17 11.6 0.6 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 EDN98440.1 - 0.016 15.0 10.3 0.22 11.3 2.8 3.2 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding COG5 PF10392.4 EDN98440.1 - 0.031 14.2 4.7 0.18 11.7 2.0 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.7 EDN98440.1 - 0.054 13.2 5.0 1.2 8.9 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 EDN98440.1 - 0.055 13.3 3.4 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMCO5 PF14992.1 EDN98440.1 - 0.056 12.5 3.4 0.096 11.8 2.0 1.6 1 1 0 1 1 1 0 TMCO5 family DUF4250 PF14056.1 EDN98440.1 - 0.07 12.8 2.0 0.32 10.7 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Fib_alpha PF08702.5 EDN98440.1 - 0.072 13.2 8.1 0.14 12.2 1.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PhoU PF01895.14 EDN98440.1 - 0.073 13.5 4.0 0.12 12.8 0.8 2.4 2 1 0 2 2 2 0 PhoU domain DUF4201 PF13870.1 EDN98440.1 - 0.08 12.3 6.7 0.73 9.2 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MutS_II PF05188.12 EDN98440.1 - 0.083 12.9 0.3 0.17 11.9 0.2 1.6 1 1 0 1 1 1 0 MutS domain II Tropomyosin_1 PF12718.2 EDN98440.1 - 0.086 12.6 4.1 1.2 8.9 1.1 2.4 2 1 0 2 2 2 0 Tropomyosin like DUF2688 PF10892.3 EDN98440.1 - 0.09 12.4 2.0 0.13 11.9 0.5 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2688) ADIP PF11559.3 EDN98440.1 - 0.097 12.5 7.6 1.5 8.7 3.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EDN98440.1 - 0.098 11.1 6.7 0.074 11.5 3.2 1.6 1 1 0 1 1 1 0 AAA domain FliD_C PF07195.7 EDN98440.1 - 0.1 11.8 2.3 6.2 6.0 1.6 2.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF1465 PF07323.7 EDN98440.1 - 0.11 11.9 2.6 1.2 8.7 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) YlqD PF11068.3 EDN98440.1 - 0.12 12.4 2.3 0.56 10.2 0.6 2.4 1 1 2 3 3 3 0 YlqD protein Phage_GP20 PF06810.6 EDN98440.1 - 0.14 11.6 2.4 0.14 11.6 0.4 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Bap31 PF05529.7 EDN98440.1 - 0.19 11.1 3.0 0.17 11.3 0.6 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 EDN98440.1 - 0.21 10.4 11.3 0.74 8.6 7.8 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EDN98440.1 - 0.22 11.0 7.6 0.18 11.3 0.8 3.2 2 2 1 3 3 3 0 Septum formation initiator DUF2730 PF10805.3 EDN98440.1 - 0.26 11.0 3.5 0.68 9.6 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) IncA PF04156.9 EDN98440.1 - 0.28 10.7 9.7 24 4.4 6.7 2.4 1 1 0 1 1 1 0 IncA protein Cluap1 PF10234.4 EDN98440.1 - 0.29 10.2 8.7 0.18 10.9 3.8 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 GrpE PF01025.14 EDN98440.1 - 0.4 10.2 3.3 1.7 8.1 1.7 2.2 2 1 0 2 2 2 0 GrpE DUF4200 PF13863.1 EDN98440.1 - 0.68 9.8 8.4 0.56 10.1 1.6 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Val_tRNA-synt_C PF10458.4 EDN98440.1 - 0.8 9.8 5.3 1 9.4 0.3 3.0 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm CENP-F_leu_zip PF10473.4 EDN98440.1 - 0.81 9.5 7.4 3.3 7.5 0.1 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EDN98440.1 - 0.88 9.3 6.1 1.2 8.9 1.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CHD5 PF04420.9 EDN98440.1 - 1.1 8.9 7.5 0.66 9.6 3.2 2.0 1 1 1 2 2 2 0 CHD5-like protein zf-C4pol PF14260.1 EDN98440.1 - 1.3 9.1 4.1 1.5 8.8 0.4 2.6 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Lebercilin PF15619.1 EDN98440.1 - 1.4 8.3 9.9 0.82 9.0 1.2 2.7 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.6 EDN98440.1 - 1.6 8.7 6.7 9.5 6.2 3.1 2.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase HeLo PF14479.1 EDN98440.1 - 1.8 8.2 7.8 7.4 6.2 5.4 1.8 1 1 0 1 1 1 0 Prion-inhibition and propagation Sipho_Gp157 PF05565.6 EDN98440.1 - 2.1 7.8 6.7 1.3 8.6 3.0 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 DUF4515 PF14988.1 EDN98440.1 - 2.1 7.9 7.7 0.96 9.0 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) DASH_Duo1 PF08651.5 EDN98440.1 - 3 7.4 5.4 7.8 6.1 0.1 3.2 2 1 2 4 4 4 0 DASH complex subunit Duo1 Rab5-bind PF09311.6 EDN98440.1 - 4 7.2 8.0 0.63 9.9 0.3 2.7 2 2 0 2 2 2 0 Rabaptin-like protein FlaC_arch PF05377.6 EDN98440.1 - 4.2 7.3 7.7 6 6.8 0.1 3.7 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF16 PF01519.11 EDN98440.1 - 4.8 7.4 6.9 6.6 7.0 3.6 2.1 2 1 0 2 2 1 0 Protein of unknown function DUF16 Thioredoxin PF00085.15 EDN98441.1 - 8.7e-44 147.4 0.5 8.9e-26 89.5 0.0 4.9 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EDN98441.1 - 4.7e-13 49.3 0.0 2.1e-06 27.6 0.0 4.2 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EDN98441.1 - 2.5e-09 37.2 0.2 0.01 16.0 0.1 4.7 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN98441.1 - 2.6e-07 30.6 0.1 0.0046 17.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EDN98441.1 - 0.00058 19.8 2.6 0.0016 18.4 0.0 2.9 4 0 0 4 4 4 1 Thioredoxin-like HyaE PF07449.6 EDN98441.1 - 0.00084 19.2 0.0 0.96 9.3 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EDN98441.1 - 0.0081 15.9 0.1 0.089 12.6 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain DHBP_synthase PF00926.14 EDN98441.1 - 0.84 8.8 5.7 1 8.5 0.2 2.4 3 0 0 3 3 3 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Tyr-DNA_phospho PF06087.7 EDN98442.1 - 5.8e-131 437.1 0.2 8.5e-131 436.6 0.2 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EDN98442.1 - 0.0014 18.3 0.2 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.14 EDN98443.1 - 2.3e-21 75.2 0.2 2.6e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2986 PF11661.3 EDN98443.1 - 3.9 7.8 7.7 0.84 10.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Ran_BP1 PF00638.13 EDN98444.1 - 4.1e-17 62.3 0.2 3.6e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain PBP1_TM PF14812.1 EDN98444.1 - 1 9.6 0.0 1 9.6 0.0 3.4 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 EDN98445.1 - 2e-10 40.1 22.8 1.4e-06 27.9 0.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat PAS PF00989.19 EDN98446.1 - 4.1e-08 32.9 0.0 0.00046 19.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EDN98446.1 - 1.7e-07 31.5 0.0 0.0064 16.8 0.0 2.7 2 1 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EDN98446.1 - 9.4e-06 25.6 0.0 0.0099 15.9 0.0 3.1 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EDN98446.1 - 0.00088 19.2 0.0 0.053 13.5 0.0 2.5 2 0 0 2 2 2 1 PAS fold Yip1 PF04893.12 EDN98447.1 - 6.8e-13 48.4 10.0 1e-12 47.9 6.9 1.3 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EDN98447.1 - 0.0027 17.3 2.5 0.0044 16.6 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF3722 PF12519.3 EDN98447.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Epimerase PF01370.16 EDN98448.1 - 2.1e-11 43.7 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN98448.1 - 5.9e-08 31.7 0.0 8e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN98448.1 - 1.9e-07 31.2 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN98448.1 - 2.1e-06 27.2 0.0 4.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EDN98448.1 - 0.00025 20.9 0.3 0.0016 18.3 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN98448.1 - 0.034 13.8 0.1 0.079 12.6 0.0 1.6 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EDN98448.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Na_Ca_ex PF01699.19 EDN98449.1 - 5.4e-28 97.3 17.4 7.2e-16 58.0 3.8 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Dioxygenase_C PF00775.16 EDN98453.1 - 7e-50 168.8 0.0 9e-50 168.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EDN98453.1 - 3.8e-13 49.2 0.0 6.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EDN98453.1 - 4.2e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EDN98453.1 - 0.016 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Cna protein B-type domain DUF4480 PF13715.1 EDN98453.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) FAD_binding_3 PF01494.14 EDN98454.1 - 3.3e-69 233.6 0.0 3e-62 210.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EDN98454.1 - 9e-58 194.6 0.0 2e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EDN98454.1 - 3.9e-05 22.8 0.1 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EDN98454.1 - 8.1e-05 21.6 0.2 0.00014 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDN98454.1 - 8.1e-05 21.2 0.2 0.00012 20.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EDN98454.1 - 0.00019 21.3 0.4 0.00056 19.8 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN98454.1 - 0.0022 17.1 0.5 0.0041 16.2 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDN98454.1 - 0.0052 15.6 0.3 0.0091 14.8 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EDN98454.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EDN98454.1 - 0.012 15.6 0.0 0.069 13.1 0.0 2.3 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN98454.1 - 0.024 13.5 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN98454.1 - 0.028 13.3 0.1 0.055 12.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EDN98454.1 - 0.18 10.4 0.9 0.44 9.1 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Scytalone_dh PF02982.9 EDN98455.1 - 7.2e-75 249.9 2.1 9e-75 249.6 1.5 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EDN98455.1 - 1.6e-06 28.0 0.3 2.3e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 EDN98456.1 - 2e-29 102.6 0.4 2.5e-29 102.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN98456.1 - 5.1e-28 98.4 0.0 7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN98456.1 - 4.3e-15 55.8 0.1 6.2e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN98456.1 - 0.02 14.3 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 EDN98457.1 - 1.1e-27 96.6 0.2 1.5e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Rab15_effector PF15208.1 EDN98459.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Rab15 effector Abhydrolase_6 PF12697.2 EDN98460.1 - 3.9e-35 121.7 0.0 4.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN98460.1 - 4.1e-21 75.6 0.0 5.2e-14 52.3 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN98460.1 - 1.4e-18 67.0 0.1 1.1e-17 64.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EDN98460.1 - 4.5e-07 28.6 0.0 2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EDN98460.1 - 8e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EDN98460.1 - 4.2e-05 23.8 0.0 6.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EDN98460.1 - 4.4e-05 22.8 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EDN98460.1 - 0.00015 21.4 0.0 0.00047 19.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase Esterase PF00756.15 EDN98460.1 - 0.00023 20.6 0.2 0.0015 18.0 0.1 2.0 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 EDN98460.1 - 0.00031 20.0 0.1 0.19 10.9 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Lipase_3 PF01764.20 EDN98460.1 - 0.00058 19.4 0.1 0.00089 18.8 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EDN98460.1 - 0.00059 19.0 0.2 0.057 12.4 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EDN98460.1 - 0.0031 17.1 0.2 0.02 14.4 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EDN98460.1 - 0.0053 16.2 0.0 0.0089 15.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EDN98460.1 - 0.0092 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EDN98460.1 - 0.012 15.0 0.1 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EDN98460.1 - 0.041 12.7 0.1 0.2 10.5 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF676 PF05057.9 EDN98460.1 - 0.041 13.1 0.0 0.078 12.2 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.8 EDN98460.1 - 0.043 12.1 0.1 5.5 5.1 0.0 2.3 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 EDN98460.1 - 0.06 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase PF07224.6 EDN98460.1 - 0.071 11.8 0.2 0.14 10.9 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 EDN98460.1 - 0.077 12.6 0.1 0.5 10.0 0.1 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 EDN98460.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ketoacyl-synt PF00109.21 EDN98463.1 - 1.2e-75 254.2 0.0 2.3e-75 253.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDN98463.1 - 2e-50 171.9 0.2 7.4e-50 170.0 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EDN98463.1 - 3.1e-33 114.1 0.4 7.9e-33 112.8 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EDN98463.1 - 8.7e-29 101.3 0.0 1.2e-27 97.6 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EDN98463.1 - 6.4e-19 67.9 3.7 5.9e-11 42.4 0.8 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EDN98463.1 - 1.6e-16 60.3 0.0 2.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EDN98463.1 - 3.1e-07 29.6 0.0 9.6e-07 28.0 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 EDN98463.1 - 7.3e-07 29.2 0.0 0.0059 16.5 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN98463.1 - 8.6e-06 25.5 0.0 0.18 11.5 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Sec34 PF04136.10 EDN98463.1 - 0.0095 15.6 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Sec34-like family DUF2974 PF11187.3 EDN98463.1 - 0.083 12.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) RNA_pol_I_TF PF04090.7 EDN98466.1 - 3.9e-09 36.0 0.0 2.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Nop14 PF04147.7 EDN98466.1 - 0.094 10.6 15.9 0.057 11.3 5.3 2.3 2 0 0 2 2 2 0 Nop14-like family Tom37_C PF11801.3 EDN98466.1 - 0.11 12.3 3.7 3.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain SMN PF06003.7 EDN98466.1 - 2 7.4 8.1 0.65 9.0 0.7 2.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) CAP_N PF01213.14 EDN98468.1 - 9.9e-86 287.8 14.8 1.9e-85 286.9 10.2 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EDN98468.1 - 7.7e-58 194.3 0.4 1.1e-57 193.8 0.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EDN98468.1 - 0.22 10.9 1.2 1.6 8.1 0.2 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 EDN98469.1 - 7.4e-12 45.0 0.0 0.0001 21.5 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DDE_1 PF03184.14 EDN98470.1 - 5.9e-34 117.1 0.0 9.6e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98470.1 - 2.8e-11 43.0 0.0 2.6e-10 39.9 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN98470.1 - 4.9e-05 23.1 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN98470.1 - 0.00042 19.8 0.6 0.00085 18.8 0.1 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN98470.1 - 0.013 15.4 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EDN98470.1 - 0.083 12.4 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.2 EDN98470.1 - 0.11 12.1 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 EDN98470.1 - 0.12 11.7 0.5 1.4 8.4 0.0 3.0 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding MCM PF00493.18 EDN98471.1 - 9.5e-129 428.9 1.2 1.3e-128 428.4 0.8 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN98471.1 - 5.9e-18 65.5 0.1 5.8e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN98471.1 - 2.4e-07 30.1 0.0 1.9e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDN98471.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDN98471.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-RanBP PF00641.13 EDN98474.1 - 0.0016 17.5 0.5 0.0025 16.8 0.4 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 EDN98474.1 - 0.078 12.2 1.3 0.52 9.6 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain APH PF01636.18 EDN98475.1 - 4.7e-06 26.5 0.0 7.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribonucleas_3_3 PF14622.1 EDN98477.1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EDN98477.1 - 0.0072 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif La PF05383.12 EDN98478.1 - 3.7e-16 58.6 0.0 6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EDN98478.1 - 6.4e-11 42.0 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN98478.1 - 5.1e-07 29.2 0.1 1.1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98478.1 - 3.6e-06 26.7 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bac_export_2 PF01312.14 EDN98478.1 - 1 8.1 7.6 1.6 7.5 5.3 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family S4 PF01479.20 EDN98479.1 - 1.4e-15 56.4 0.0 2.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EDN98479.1 - 0.029 13.9 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain Mnd1 PF03962.10 EDN98479.1 - 0.77 9.3 6.7 1.2 8.7 4.7 1.2 1 0 0 1 1 1 0 Mnd1 family Carn_acyltransf PF00755.15 EDN98480.1 - 3.2e-182 606.7 0.0 5.1e-182 606.0 0.0 1.3 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase Cyclin_N PF00134.18 EDN98482.1 - 0.0054 16.2 0.0 0.049 13.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain PLA2_B PF01735.13 EDN98485.1 - 5.5e-21 74.3 0.0 8.2e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Glyco_hydro_67N PF03648.9 EDN98485.1 - 0.24 11.4 1.4 0.53 10.3 1.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus Exo70 PF03081.10 EDN98486.1 - 8.9e-74 248.4 0.0 2.8e-73 246.8 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit T2SF PF00482.18 EDN98486.1 - 0.056 13.3 0.0 18 5.2 0.0 3.3 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Mst1_SARAH PF11629.3 EDN98486.1 - 0.2 11.5 1.3 0.51 10.1 0.2 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Spore_III_AB PF09548.5 EDN98486.1 - 0.45 10.2 4.5 2.7 7.7 0.1 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF4208 PF13907.1 EDN98486.1 - 5 7.4 6.1 3 8.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) OPT PF03169.10 EDN98487.1 - 5.5e-156 520.6 50.6 8.4e-150 500.1 29.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein KGG PF10685.4 EDN98488.1 - 1.7 8.7 3.8 1.1 9.2 0.4 2.1 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif ETC_C1_NDUFA5 PF04716.9 EDN98493.1 - 1.5e-24 85.2 1.4 2.4e-23 81.4 0.0 2.3 2 0 0 2 2 2 2 ETC complex I subunit conserved region Eaf7 PF07904.8 EDN98494.1 - 8.7e-32 108.9 0.0 1.6e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 EDN98495.1 - 1.3e-77 261.3 3.6 2.1e-77 260.6 2.5 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3328 PF11807.3 EDN98496.1 - 4.3e-30 105.0 1.5 5.5e-30 104.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EDN98499.1 - 3.5e-27 95.5 0.3 4.3e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.1 EDN98500.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN98500.1 - 0.0023 18.2 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN98500.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EDN98502.1 - 9.9e-16 58.3 0.3 1.4e-15 57.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN98502.1 - 6.3e-06 26.0 0.0 7.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Isochorismatase PF00857.15 EDN98503.1 - 5.2e-43 146.9 0.0 6.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Tyrosinase PF00264.15 EDN98505.1 - 3e-62 210.6 0.7 5.6e-62 209.8 0.5 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 EDN98507.1 - 6e-112 374.1 0.1 8.1e-112 373.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDN98507.1 - 6.1e-29 100.4 0.0 8.5e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EDN98507.1 - 1.3e-24 85.9 0.0 3.2e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EDN98507.1 - 3.3e-24 85.3 0.0 5.4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDN98507.1 - 1.6e-13 50.6 0.0 4.8e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EDN98507.1 - 2.1e-05 24.4 0.1 5.8e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EDN98507.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Rpr2 PF04032.11 EDN98507.1 - 0.016 15.0 0.6 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.16 EDN98508.1 - 2.1e-33 115.0 0.1 1.7e-30 105.5 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDN98508.1 - 1.8e-12 46.9 0.0 2.7e-11 43.0 0.0 1.9 1 1 1 2 2 2 1 Ras family Miro PF08477.8 EDN98508.1 - 6e-08 33.2 0.0 3.5e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EDN98508.1 - 9.7e-05 21.6 0.0 0.0023 17.1 0.0 2.0 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDN98508.1 - 0.00021 20.5 0.0 0.22 10.7 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EDN98508.1 - 0.00034 20.0 0.0 0.0069 15.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN98508.1 - 0.00052 19.9 0.0 0.032 14.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EDN98508.1 - 0.00063 18.5 0.1 0.0012 17.6 0.1 1.7 1 1 0 1 1 1 1 G-protein alpha subunit PduV-EutP PF10662.4 EDN98508.1 - 0.057 12.8 0.1 2 7.8 0.1 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EDN98508.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Macin PF14865.1 EDN98509.1 - 0.23 11.6 2.0 0.27 11.3 1.4 1.1 1 0 0 1 1 1 0 Macin RCR PF12273.3 EDN98510.1 - 4.6e-30 104.8 7.0 4.6e-30 104.8 4.9 1.4 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EDN98510.1 - 0.00016 21.3 0.1 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Rhabdo_glycop PF00974.13 EDN98510.1 - 0.012 13.8 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein IncA PF04156.9 EDN98510.1 - 0.031 13.8 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 IncA protein ATG27 PF09451.5 EDN98510.1 - 0.039 13.1 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Cytochrom_B_N PF00033.14 EDN98510.1 - 0.09 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB RVT_1 PF00078.22 EDN98513.1 - 6e-27 94.3 0.2 1.2e-26 93.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN98513.1 - 7.5e-15 55.4 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN98513.1 - 0.0077 16.5 0.4 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase WD40 PF00400.27 EDN98514.1 - 1e-14 53.7 0.1 1.9e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_10 PF13374.1 EDN98515.1 - 3.3e-51 169.8 0.6 3.1e-12 46.0 0.0 6.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN98515.1 - 1.8e-46 155.9 0.0 1.7e-13 50.3 0.0 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat HET PF06985.6 EDN98515.1 - 1e-23 84.0 8.4 8.3e-22 77.8 5.9 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.1 EDN98515.1 - 2.2e-15 55.1 0.7 0.023 14.4 0.0 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EDN98515.1 - 3.9e-12 45.6 0.0 6.8e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EDN98515.1 - 6.1e-10 38.5 0.4 0.7 10.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN98515.1 - 6e-08 31.9 0.1 2.2 8.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EDN98515.1 - 9.4e-08 32.2 0.0 3.7e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN98515.1 - 1.6e-07 31.5 0.0 6.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.1 EDN98515.1 - 5.2e-07 29.2 0.0 0.058 13.0 0.1 3.8 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.12 EDN98515.1 - 1e-06 28.1 2.3 3.9 7.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN98515.1 - 1.5e-06 28.0 0.0 16 6.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.7 EDN98515.1 - 2.2e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.1 EDN98515.1 - 2.7e-05 24.3 0.0 5.4 7.4 0.0 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN98515.1 - 0.00013 22.2 2.0 43 5.1 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN98515.1 - 0.00058 20.4 0.1 7.5 7.3 0.1 4.8 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN98515.1 - 0.0019 17.8 0.2 31 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EDN98515.1 - 0.002 18.0 4.7 12 5.7 0.1 4.8 2 1 3 5 5 5 0 Rabaptin-like protein TPR_6 PF13174.1 EDN98515.1 - 0.0091 16.3 1.0 54 4.5 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2075 PF09848.4 EDN98515.1 - 0.057 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EDN98515.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EDN98515.1 - 0.13 12.1 0.0 0.46 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EDN98515.1 - 0.2 10.9 0.0 0.42 9.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Transpep_BrtH PF14399.1 EDN98516.1 - 0.027 13.7 0.1 0.029 13.6 0.1 1.0 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Phage-MuB_C PF09077.6 EDN98516.1 - 0.083 12.5 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Mu B transposition protein, C terminal H_lectin PF09458.5 EDN98516.1 - 0.09 12.4 1.2 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 H-type lectin domain DDE_1 PF03184.14 EDN98517.1 - 5.4e-39 133.5 0.0 8.6e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98517.1 - 3.1e-08 33.3 0.0 2.7e-07 30.3 0.0 2.5 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN98517.1 - 1.2e-06 28.3 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN98517.1 - 0.00048 19.6 0.3 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN98517.1 - 0.0027 17.6 0.1 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3400 PF11880.3 EDN98517.1 - 0.0043 16.2 0.2 0.5 9.6 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3400) Mga PF05043.8 EDN98517.1 - 0.028 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain Rad60-SLD PF11976.3 EDN98517.1 - 0.052 13.2 0.3 0.45 10.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UPF0180 PF03698.8 EDN98517.1 - 0.055 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) HTH_AsnC-type PF13404.1 EDN98517.1 - 0.088 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rap1-DNA-bind PF09197.5 EDN98517.1 - 0.12 12.9 0.3 1.6 9.3 0.0 2.7 3 0 0 3 3 3 0 Rap1, DNA-binding RNase_H PF00075.19 EDN98518.1 - 9.3e-08 32.4 0.5 1.9e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 RNase H GnsAB PF08178.6 EDN98518.1 - 0.011 15.3 0.1 0.044 13.4 0.0 2.0 1 0 0 1 1 1 0 GnsA/GnsB family FumaraseC_C PF10415.4 EDN98518.1 - 0.064 13.3 0.6 0.58 10.2 0.4 2.4 2 0 0 2 2 2 0 Fumarase C C-terminus TRF PF08558.5 EDN98520.1 - 2.2e-60 203.9 0.0 4.5e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EDN98520.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aldedh PF00171.17 EDN98521.1 - 3.2e-69 233.4 0.2 3.6e-69 233.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CotJA PF11007.3 EDN98521.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) Colicin_V PF02674.11 EDN98523.1 - 0.0046 16.8 0.3 0.0063 16.3 0.2 1.2 1 0 0 1 1 1 1 Colicin V production protein F-box PF00646.28 EDN98523.1 - 0.062 12.9 0.2 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 F-box domain SseC PF04888.7 EDN98523.1 - 0.16 11.2 0.9 0.2 10.9 0.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4006 PF13179.1 EDN98523.1 - 0.76 9.3 3.2 1.4 8.5 2.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PepSY_TM_2 PF13703.1 EDN98524.1 - 0.077 13.1 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM helix DUF2208 PF09973.4 EDN98524.1 - 0.13 11.4 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Ferritin PF00210.19 EDN98525.1 - 0.038 13.7 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF2183 PF09949.4 EDN98526.1 - 2.9e-19 68.8 0.1 5.7e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Cutinase PF01083.17 EDN98527.1 - 3.2e-51 173.6 4.6 4.2e-51 173.2 3.2 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EDN98527.1 - 0.019 14.3 0.2 0.037 13.4 0.2 1.5 1 0 0 1 1 1 0 PE-PPE domain DUF2435 PF10363.4 EDN98529.1 - 1.6e-16 59.9 0.4 8.8e-16 57.5 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EDN98529.1 - 3.4e-09 35.9 0.0 7.5e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF2183 PF09949.4 EDN98531.1 - 2.9e-27 94.5 0.1 8.1e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Dyp_perox PF04261.7 EDN98532.1 - 2.9e-09 36.1 2.5 1e-07 31.0 0.2 3.3 3 1 0 3 3 3 2 Dyp-type peroxidase family NUDIX-like PF09296.6 EDN98532.1 - 0.065 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain F5_F8_type_C PF00754.20 EDN98533.1 - 7.3e-21 74.3 0.1 1.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.1 EDN98533.1 - 1.3e-17 63.1 1.8 4.9e-05 23.3 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EDN98533.1 - 2.3e-15 55.8 0.1 1.6e-05 24.3 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EDN98533.1 - 1.2e-13 50.6 10.4 8.2e-05 22.3 0.1 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EDN98533.1 - 1.3e-12 46.9 0.8 2.7e-06 26.9 0.1 5.2 4 1 0 4 4 4 2 Kelch motif Glyoxal_oxid_N PF07250.6 EDN98533.1 - 1.9e-10 40.2 0.2 4.2e-05 22.7 0.1 2.7 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 EDN98533.1 - 0.003 17.6 8.1 1.7 8.8 0.0 5.5 5 2 1 6 6 6 1 Galactose oxidase, central domain PQQ_3 PF13570.1 EDN98533.1 - 0.052 13.8 5.8 5.8 7.3 0.0 4.5 4 1 0 4 4 4 0 PQQ-like domain Ada3 PF10198.4 EDN98534.1 - 0.028 14.1 1.0 0.065 12.9 0.7 1.6 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 YhjQ PF06564.7 EDN98536.1 - 0.023 14.0 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein MFS_1 PF07690.11 EDN98538.1 - 1.3e-49 168.8 39.9 8.2e-49 166.1 28.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN98538.1 - 6.2e-14 51.1 26.1 7.6e-13 47.5 18.1 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN98538.1 - 1e-10 40.8 13.0 1e-10 40.8 9.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter zf-RING_2 PF13639.1 EDN98539.1 - 2.7e-08 33.5 4.0 4.9e-08 32.6 2.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDN98539.1 - 4.8e-06 26.5 0.8 8.1e-06 25.8 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDN98539.1 - 0.0019 17.7 0.5 0.0036 16.9 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN98539.1 - 0.0021 17.8 1.3 0.0034 17.1 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EDN98539.1 - 0.014 15.4 3.3 0.026 14.5 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN98539.1 - 0.19 11.3 1.8 0.37 10.4 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 EDN98540.1 - 1.6e-23 82.3 0.1 2e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.12 EDN98541.1 - 1.1e-75 254.1 0.0 2.2e-60 204.0 0.0 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit IBR PF01485.16 EDN98543.1 - 5e-08 32.6 41.8 1.5e-05 24.8 8.7 3.8 3 1 0 3 3 3 2 IBR domain DUF4062 PF13271.1 EDN98544.1 - 0.053 13.5 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) UPF0150 PF03681.10 EDN98544.1 - 0.26 10.9 1.5 0.31 10.7 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) zf-C2H2_4 PF13894.1 EDN98545.1 - 0.013 15.8 1.8 3.5 8.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger AT_hook PF02178.14 EDN98545.1 - 0.017 14.7 29.4 0.061 13.0 1.8 4.1 4 0 0 4 4 4 0 AT hook motif DDE_1 PF03184.14 EDN98547.1 - 3.1e-16 59.1 0.1 5.6e-16 58.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98547.1 - 2.1e-09 37.0 0.1 7.6e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ADH_N PF08240.7 EDN98550.1 - 2.3e-30 104.5 2.5 2.8e-30 104.2 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN98550.1 - 1.3e-25 89.4 0.1 1.3e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN98550.1 - 0.013 14.6 0.2 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EDN98550.1 - 0.09 12.7 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding FeoA PF04023.9 EDN98550.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 FeoA domain tRNA_U5-meth_tr PF05958.6 EDN98555.1 - 1.2e-12 47.2 0.0 1.5e-11 43.5 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EDN98555.1 - 1.6e-06 27.7 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EDN98555.1 - 1.1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EDN98555.1 - 0.00052 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EDN98555.1 - 0.00067 19.3 0.1 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 EDN98555.1 - 0.0011 18.2 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDN98555.1 - 0.0022 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.4 EDN98555.1 - 0.014 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.10 EDN98555.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.9 EDN98555.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EDN98555.1 - 0.056 13.9 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDN98555.1 - 0.14 12.6 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain BLVR PF06375.6 EDN98557.1 - 0.017 14.9 0.4 0.02 14.7 0.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3166 PF11365.3 EDN98557.1 - 0.072 13.5 0.6 0.12 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) Ribosomal_S5_C PF03719.10 EDN98562.1 - 4.4e-20 70.7 0.1 8.5e-20 69.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EDN98562.1 - 1.3e-07 31.2 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 EDN98563.1 - 5e-30 103.0 0.6 5.8e-30 102.8 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF2317 PF10079.4 EDN98563.1 - 0.039 12.5 0.1 0.047 12.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF2935 PF11155.3 EDN98563.1 - 0.12 12.5 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Actin PF00022.14 EDN98564.1 - 1.8e-59 201.1 0.0 3.9e-50 170.4 0.0 2.6 2 1 0 2 2 2 2 Actin Asparaginase_2 PF01112.13 EDN98565.1 - 5.4e-37 127.2 3.1 1.6e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EDN98566.1 - 2.2e-110 368.2 0.7 2.6e-110 368.0 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.3 EDN98567.1 - 1e-53 181.1 1.9 9.7e-52 174.7 0.0 3.0 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EDN98567.1 - 3.2e-05 24.1 11.7 1.7 9.0 0.6 6.9 6 2 1 7 7 7 3 HEAT repeats Mo25 PF08569.6 EDN98567.1 - 0.058 12.4 2.1 0.72 8.8 0.0 2.9 4 0 0 4 4 4 0 Mo25-like DUF3243 PF11588.3 EDN98568.1 - 0.041 13.8 1.2 0.062 13.3 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3243) Pkinase PF00069.20 EDN98568.1 - 0.055 12.6 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain VHS PF00790.14 EDN98569.1 - 1.9e-24 85.8 0.0 5.3e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EDN98569.1 - 3.1e-10 39.9 0.7 7e-10 38.7 0.5 1.6 1 0 0 1 1 1 1 GAT domain Herpes_US9 PF06072.6 EDN98571.1 - 0.0098 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF1180 PF06679.7 EDN98571.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Fucose_iso_N1 PF07881.7 EDN98572.1 - 0.072 12.6 0.4 0.19 11.2 0.2 1.7 1 1 0 2 2 2 0 L-fucose isomerase, first N-terminal domain B12-binding PF02310.14 EDN98572.1 - 0.094 12.5 0.0 0.75 9.6 0.0 1.9 1 1 1 2 2 2 0 B12 binding domain Sulf_transp PF04143.9 EDN98573.1 - 7.9e-15 54.6 37.1 2.7e-09 36.9 7.1 4.2 3 2 0 3 3 3 2 Sulphur transport DUF4341 PF14241.1 EDN98573.1 - 0.0052 16.4 4.8 0.0052 16.4 3.3 4.7 5 2 0 5 5 5 1 Domain of unknown function (DUF4341) PBP1_TM PF14812.1 EDN98575.1 - 0.09 13.1 2.9 0.11 12.8 2.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIF_C PF14721.1 EDN98575.1 - 0.29 11.3 8.4 0.32 11.2 5.8 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FLO_LFY PF01698.11 EDN98575.1 - 2.6 6.7 9.9 2.7 6.7 6.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein NPR3 PF03666.8 EDN98575.1 - 9 4.7 11.8 9.8 4.5 8.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OATP PF03137.15 EDN98575.1 - 9.1 4.2 8.5 9.4 4.1 5.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family zf-CHY PF05495.7 EDN98578.1 - 3.2e-15 56.0 12.5 3.2e-15 56.0 8.7 3.4 3 1 0 3 3 3 2 CHY zinc finger RWD PF05773.17 EDN98578.1 - 0.00061 19.6 0.4 0.02 14.8 0.0 2.7 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.4 EDN98578.1 - 0.013 14.4 0.7 0.05 12.6 0.5 2.1 1 0 0 1 1 1 0 Mu-like prophage protein Com UQ_con PF00179.21 EDN98578.1 - 0.052 12.9 0.1 0.2 11.0 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme zf-CCCH_2 PF14608.1 EDN98578.1 - 0.053 13.5 0.5 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Pox_A21 PF05323.7 EDN98582.1 - 0.13 12.6 0.1 0.15 12.4 0.1 1.0 1 0 0 1 1 1 0 Poxvirus A21 Protein DUF3295 PF11702.3 EDN98584.1 - 6.7e-187 622.5 32.2 8.6e-187 622.1 22.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EDN98584.1 - 3.8e-11 42.3 1.6 8.1e-11 41.3 1.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DAZAP2 PF11029.3 EDN98584.1 - 0.1 13.0 1.1 0.26 11.7 0.7 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Chromo PF00385.19 EDN98589.1 - 1.1e-12 47.4 0.8 1.1e-12 47.4 0.6 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EDN98589.1 - 2.4e-12 46.5 0.1 1.8e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain DUF2360 PF10152.4 EDN98589.1 - 0.037 14.2 0.2 0.037 14.2 0.1 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HTH_Tnp_Tc5 PF03221.11 EDN98590.1 - 1.8e-05 24.4 0.0 1.8e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Paramyxo_C PF01692.13 EDN98591.1 - 0.32 10.5 5.7 0.36 10.4 4.0 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c DUF4614 PF15391.1 EDN98591.1 - 2.7 7.7 12.5 3.3 7.4 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SOBP PF15279.1 EDN98591.1 - 4.7 7.5 7.5 5.3 7.3 5.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein SAP PF02037.22 EDN98592.1 - 3.6e-10 39.0 0.6 7e-10 38.1 0.4 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 EDN98592.1 - 7.2e-07 28.9 4.5 7.2e-07 28.9 3.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDN98592.1 - 0.00022 21.2 4.0 0.00052 20.0 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN98592.1 - 0.00064 19.5 2.9 0.00064 19.5 2.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EDN98592.1 - 0.0092 15.9 4.3 0.031 14.2 3.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDN98592.1 - 0.0093 15.6 6.3 0.021 14.4 4.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.1 EDN98592.1 - 0.066 12.8 6.9 0.15 11.6 4.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mto2_bdg PF12808.2 EDN98592.1 - 0.095 12.8 0.5 0.24 11.5 0.3 1.7 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FANCL_C PF11793.3 EDN98592.1 - 0.38 10.7 11.0 0.064 13.2 4.4 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EDN98592.1 - 0.38 10.5 7.1 0.091 12.5 1.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EDN98592.1 - 3 7.6 7.6 1.6 8.5 2.3 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 EDN98592.1 - 3.2 7.8 7.5 2.3 8.2 0.7 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Dynamin_M PF01031.15 EDN98593.1 - 1.2e-20 73.4 1.0 4e-18 65.2 0.3 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EDN98593.1 - 2.3e-19 69.8 0.5 9.4e-19 67.8 0.0 2.4 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EDN98593.1 - 3.3e-05 23.8 0.5 0.00048 20.0 0.4 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EDN98593.1 - 8.8e-05 22.3 0.1 0.00039 20.2 0.1 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 EDN98593.1 - 0.0075 16.7 0.3 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EDN98593.1 - 0.019 15.2 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NTP_transferase PF00483.18 EDN98594.1 - 4.9e-28 98.0 0.0 6.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EDN98594.1 - 1.4e-08 33.8 7.6 3.8e-06 26.1 0.0 3.9 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDN98594.1 - 8.3e-07 29.2 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF459 PF04311.8 EDN98594.1 - 0.026 13.3 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF459) IspD PF01128.14 EDN98594.1 - 0.036 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EDN98594.1 - 0.35 10.4 2.6 2.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Oxidored_FMN PF00724.15 EDN98596.1 - 1.1e-62 212.0 0.0 1.5e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SGT1 PF07093.6 EDN98599.1 - 0.13 10.6 2.3 0.7 8.2 1.6 1.9 1 1 0 1 1 1 0 SGT1 protein FlxA PF14282.1 EDN98599.1 - 0.26 11.2 10.6 0.52 10.2 7.4 1.4 1 0 0 1 1 1 0 FlxA-like protein Band_7 PF01145.20 EDN98600.1 - 7.3e-15 55.3 0.2 7.3e-15 55.3 0.1 4.2 2 1 2 4 4 4 1 SPFH domain / Band 7 family VPS11_C PF12451.3 EDN98603.1 - 2.6e-19 68.7 1.3 6e-19 67.6 0.3 2.1 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 EDN98603.1 - 2.9e-19 69.0 1.1 2.4e-17 62.8 0.1 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EDN98603.1 - 0.00051 19.8 6.1 0.0016 18.2 3.9 2.1 2 0 0 2 2 2 1 Ring finger domain TPR_14 PF13428.1 EDN98603.1 - 0.0011 19.3 0.6 3.1 8.6 0.1 3.6 2 1 1 3 3 2 1 Tetratricopeptide repeat zf-Apc11 PF12861.2 EDN98603.1 - 0.0015 18.3 1.3 0.0042 16.8 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_19 PF14559.1 EDN98603.1 - 0.0016 18.6 1.8 2.6 8.4 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 EDN98603.1 - 0.0021 17.7 6.3 0.0043 16.7 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EDN98603.1 - 0.0057 16.2 0.2 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EDN98603.1 - 0.0079 15.9 2.2 0.099 12.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EDN98603.1 - 0.014 15.3 4.6 0.038 14.0 3.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 EDN98603.1 - 0.018 14.9 4.7 0.71 9.8 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat SPOB_a PF14689.1 EDN98603.1 - 0.019 14.5 0.7 0.8 9.3 0.1 2.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain zf-rbx1 PF12678.2 EDN98603.1 - 0.029 14.4 2.5 0.098 12.7 1.8 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN98603.1 - 0.052 13.2 4.8 0.11 12.2 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.1 EDN98603.1 - 0.065 13.9 0.9 2.1 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN98603.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.3 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EDN98603.1 - 0.33 10.6 3.4 0.64 9.7 2.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.6 EDN98603.1 - 0.58 9.9 4.3 0.47 10.2 0.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_1 PF00515.23 EDN98603.1 - 1.8 8.2 4.4 2.6 7.8 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat PHD PF00628.24 EDN98603.1 - 2.4 7.8 6.3 5.7 6.7 4.4 1.7 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_6 PF14599.1 EDN98604.1 - 0.18 11.6 0.5 0.18 11.6 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon RRM_1 PF00076.17 EDN98605.1 - 1.2e-11 44.0 0.0 5.4e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN98605.1 - 3.4e-10 39.7 0.0 7.4e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98605.1 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EDN98605.1 - 5.3e-05 23.5 12.4 7.2e-05 23.1 0.7 2.6 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 EDN98605.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family Ost4 PF10215.4 EDN98606.1 - 9e-17 60.2 0.3 1.2e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase DUF3357 PF11837.3 EDN98606.1 - 0.016 15.0 0.1 0.018 14.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Bac_rhodopsin PF01036.13 EDN98606.1 - 0.095 11.9 0.0 0.095 11.9 0.0 1.0 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein SVA PF05326.6 EDN98606.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) zf-CCCH PF00642.19 EDN98607.1 - 3e-05 23.5 3.5 3e-05 23.5 2.5 2.4 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 EDN98607.1 - 0.029 14.0 0.5 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase CCDC-167 PF15188.1 EDN98607.1 - 1.7 8.6 6.4 2.1 8.3 0.7 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Sulfatase_C PF14707.1 EDN98608.1 - 0.0077 16.5 0.5 0.018 15.3 0.2 1.7 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Cluap1 PF10234.4 EDN98608.1 - 3.3 6.8 17.4 1.2 8.2 10.2 1.6 1 1 1 2 2 2 0 Clusterin-associated protein-1 Protamine_P2 PF00841.14 EDN98609.1 - 0.13 12.8 1.1 0.19 12.3 0.7 1.2 1 0 0 1 1 1 0 Sperm histone P2 Virulence_fact PF13769.1 EDN98609.1 - 0.16 11.8 2.9 0.22 11.4 2.0 1.3 1 0 0 1 1 1 0 Virulence factor bZIP_2 PF07716.10 EDN98610.1 - 1.1e-06 28.3 9.7 1.4e-06 27.9 6.7 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN98610.1 - 1.9e-06 27.7 7.0 2.4e-06 27.3 4.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDN98610.1 - 0.00021 21.5 4.1 0.00024 21.3 2.8 1.0 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-F_leu_zip PF10473.4 EDN98610.1 - 0.01 15.7 1.2 0.013 15.3 0.6 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TEX13 PF15186.1 EDN98610.1 - 0.013 15.0 1.3 0.015 14.8 0.9 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Striatin PF08232.7 EDN98610.1 - 0.014 15.6 1.3 0.018 15.3 0.3 1.6 1 1 1 2 2 2 0 Striatin family TPD52 PF04201.10 EDN98610.1 - 0.018 14.7 1.0 0.019 14.6 0.7 1.2 1 0 0 1 1 1 0 Tumour protein D52 family TMF_DNA_bd PF12329.3 EDN98610.1 - 0.018 14.7 2.6 0.022 14.5 1.6 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EDN98610.1 - 0.024 14.3 1.6 0.026 14.2 1.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EDN98610.1 - 0.036 13.5 0.6 0.043 13.2 0.4 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF869 PF05911.6 EDN98610.1 - 0.047 11.9 2.8 0.047 11.9 2.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4140 PF13600.1 EDN98610.1 - 0.054 13.9 2.5 0.064 13.7 1.8 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SLX9 PF15341.1 EDN98610.1 - 0.069 13.5 2.8 0.075 13.4 1.9 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 WD40_alt PF14077.1 EDN98610.1 - 0.1 12.2 0.3 0.2 11.2 0.2 1.6 1 1 0 1 1 1 0 Alternative WD40 repeat motif Viral_P18 PF04521.8 EDN98610.1 - 0.12 11.7 0.9 0.14 11.6 0.6 1.3 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2205 PF10224.4 EDN98610.1 - 0.34 10.5 2.4 0.39 10.3 1.6 1.1 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) p450 PF00067.17 EDN98611.1 - 4.8e-55 186.9 0.0 2.7e-27 95.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Alpha-amylase PF00128.19 EDN98613.1 - 3.6e-51 174.4 1.6 5.3e-51 173.8 1.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN98613.1 - 5.7e-25 87.2 0.1 1.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Pyridox_oxidase PF01243.15 EDN98614.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase UPF0154 PF03672.8 EDN98614.1 - 0.83 9.3 3.2 33 4.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Metallophos PF00149.23 EDN98615.1 - 1.3e-38 132.3 0.1 2.2e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Smg4_UPF3 PF03467.10 EDN98616.1 - 1.6e-25 90.1 1.0 5e-25 88.5 0.0 2.2 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 EDN98616.1 - 1.2e-07 31.6 0.3 7.1e-07 29.1 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN98616.1 - 4.4e-06 26.2 0.0 4.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98616.1 - 1.6e-05 24.6 0.0 5.1e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_AsnC-type PF13404.1 EDN98616.1 - 0.3 10.6 2.2 0.39 10.2 0.1 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain NARP1 PF12569.3 EDN98616.1 - 3.1 6.4 9.5 5.1 5.7 6.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF829 PF05705.9 EDN98618.1 - 1.5e-30 106.7 0.0 1.8e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ATPgrasp_Ter PF15632.1 EDN98619.1 - 0.031 13.0 0.0 0.032 12.9 0.0 1.0 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon V_ATPase_I PF01496.14 EDN98620.1 - 0.02 12.7 7.9 0.024 12.5 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 EDN98620.1 - 0.09 12.6 15.4 1.3 8.9 1.3 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 EDN98620.1 - 0.094 12.7 15.2 0.6 10.1 2.1 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Peptidase_M16 PF00675.15 EDN98620.1 - 0.25 11.1 1.7 0.41 10.4 1.2 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) DUF972 PF06156.8 EDN98620.1 - 0.47 10.8 14.8 1.1 9.5 1.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) CENP-H PF05837.7 EDN98620.1 - 0.53 10.4 12.9 0.092 12.9 5.2 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Tropomyosin PF00261.15 EDN98620.1 - 0.53 9.3 20.4 0.082 11.9 10.5 1.9 2 0 0 2 2 2 0 Tropomyosin Rootletin PF15035.1 EDN98620.1 - 1.1 9.2 20.5 0.11 12.4 7.7 2.6 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EDN98620.1 - 2.2 7.8 18.2 7.8 6.0 12.6 1.7 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EDN98620.1 - 4.8 7.0 19.8 3.1 7.6 10.3 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc42p PF11544.3 EDN98620.1 - 5.3 7.0 16.1 0.92 9.4 0.3 3.3 2 1 1 3 3 3 0 Spindle pole body component Spc42p CENP-Q PF13094.1 EDN98620.1 - 7.3 6.5 14.4 0.41 10.6 3.6 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 EDN98620.1 - 8.7 6.1 7.6 5.8 6.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EDN98620.1 - 9.6 5.1 13.7 0.85 8.6 6.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Tmemb_cc2 PF10267.4 EDN98621.1 - 0.011 14.4 4.7 0.02 13.5 3.2 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Herpes_U30 PF04523.8 EDN98621.1 - 0.021 12.3 1.0 0.027 11.9 0.7 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 IncA PF04156.9 EDN98621.1 - 0.059 12.9 5.5 0.1 12.2 3.8 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EDN98621.1 - 0.16 10.3 5.6 0.21 9.9 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup54 PF13874.1 EDN98621.1 - 0.29 10.7 10.3 0.019 14.6 3.7 1.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Laminin_II PF06009.7 EDN98621.1 - 0.37 10.5 6.0 0.55 9.9 4.2 1.2 1 0 0 1 1 1 0 Laminin Domain II V_ATPase_I PF01496.14 EDN98621.1 - 2.8 5.6 5.2 3.7 5.3 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.7 EDN98621.1 - 3.5 7.3 8.5 0.24 11.1 2.4 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EDN98621.1 - 6 7.2 10.0 0.39 11.0 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Methyltransf_11 PF08241.7 EDN98623.1 - 7.6e-16 58.3 0.0 1.4e-15 57.5 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN98623.1 - 1.6e-09 37.6 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN98623.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN98623.1 - 2.6e-09 37.4 0.0 3.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN98623.1 - 1e-08 35.7 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN98623.1 - 1.6e-08 34.7 0.0 2.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN98623.1 - 8.5e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN98623.1 - 1.9e-05 24.0 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EDN98623.1 - 0.00019 20.6 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EDN98623.1 - 0.0066 15.1 0.0 0.0066 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EDN98623.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 EDN98623.1 - 0.018 14.4 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EDN98623.1 - 0.05 12.7 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Thr_synth_N PF14821.1 EDN98624.1 - 1.9e-29 101.4 0.0 4.8e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EDN98624.1 - 5.4e-24 84.9 0.0 2.8e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_4 PF13637.1 EDN98625.1 - 7.1e-06 26.3 0.0 3.7e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN98625.1 - 0.0017 18.5 0.0 0.013 15.7 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN98625.1 - 0.0022 18.3 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1838 PF08894.6 EDN98630.1 - 0.048 12.8 0.0 0.055 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Fe-ADH PF00465.14 EDN98632.1 - 5e-104 347.8 0.0 6.3e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EDN98632.1 - 9.4e-15 54.5 0.0 7.8e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EDN98632.1 - 0.023 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein B12-binding PF02310.14 EDN98632.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain ATG13 PF10033.4 EDN98633.1 - 5.8e-70 235.3 0.0 1.8e-69 233.7 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 DUF4142 PF13628.1 EDN98637.1 - 0.12 12.4 1.5 0.13 12.2 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Atx10homo_assoc PF09759.4 EDN98638.1 - 4.4e-13 48.8 0.1 4.3e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DZR PF12773.2 EDN98638.1 - 0.023 14.4 0.4 0.049 13.4 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EDN98638.1 - 0.039 13.4 1.5 0.084 12.3 1.0 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit YopE PF03545.8 EDN98638.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) zinc_ribbon_2 PF13240.1 EDN98638.1 - 1.3 8.5 4.2 30 4.2 2.9 2.6 1 1 0 1 1 1 0 zinc-ribbon domain ABC2_membrane PF01061.19 EDN98639.1 - 2.5e-35 121.5 34.6 1.7e-25 89.4 7.9 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EDN98639.1 - 3e-30 103.9 0.1 1.8e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EDN98639.1 - 1.5e-11 44.7 0.0 1.4e-09 38.3 0.0 2.3 1 1 1 2 2 2 1 ABC transporter AAA_25 PF13481.1 EDN98639.1 - 2.9e-06 26.8 0.0 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDN98639.1 - 1.6e-05 25.0 0.1 0.033 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EDN98639.1 - 0.00018 20.7 28.4 0.0023 17.0 6.3 2.6 2 1 1 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 EDN98639.1 - 0.0003 20.0 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EDN98639.1 - 0.00089 18.5 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN98639.1 - 0.0058 16.1 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN98639.1 - 0.05 13.5 0.3 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EDN98639.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDN98639.1 - 0.087 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN98639.1 - 0.1 13.4 0.0 0.2 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EDN98639.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDN98639.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EDN98639.1 - 0.2 11.0 0.2 0.32 10.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 EDN98640.1 - 1.7e-14 53.6 0.0 3.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EDN98640.1 - 3.2e-13 50.1 0.0 5.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Apolipoprotein PF01442.13 EDN98641.1 - 0.034 13.6 2.4 0.052 13.0 1.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PH PF00169.24 EDN98641.1 - 0.037 14.2 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 PH domain Bac_rhamnosid PF05592.6 EDN98642.1 - 1.2e-34 119.3 2.2 1.1e-26 93.1 2.3 2.4 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Zds_C PF08632.5 EDN98643.1 - 4.2e-31 106.1 0.9 7.2e-31 105.3 0.6 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term VHS PF00790.14 EDN98644.1 - 1.5e-34 118.6 0.6 2.9e-34 117.6 0.4 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EDN98644.1 - 1.3e-17 63.0 0.0 2.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN98644.1 - 4e-15 54.9 0.0 7.9e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDN98644.1 - 1.2e-13 50.2 0.0 2.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EDN98644.1 - 0.063 12.8 1.8 0.19 11.4 1.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Sugar_tr PF00083.19 EDN98647.1 - 8.5e-79 265.2 22.1 9.9e-79 265.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN98647.1 - 6.8e-29 100.6 25.8 8.3e-23 80.6 6.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1360 PF07098.6 EDN98647.1 - 2 8.1 5.9 14 5.4 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1360) AA_permease_C PF13906.1 EDN98647.1 - 8.4 6.3 12.9 0.093 12.6 0.7 3.4 3 0 0 3 3 3 0 C-terminus of AA_permease HECT PF00632.20 EDN98649.1 - 7.5e-71 238.8 0.0 1.3e-70 238.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EDN98650.1 - 4.7e-30 103.6 1.9 4.7e-30 103.6 1.3 4.0 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EDN98650.1 - 0.0052 16.5 2.2 0.0065 16.2 0.1 2.3 2 1 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 EDN98650.1 - 0.081 13.0 0.0 0.081 13.0 0.0 4.7 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDN98650.1 - 0.33 11.3 11.9 0.2 12.0 0.3 4.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 EDN98650.1 - 1.3 9.3 9.7 0.84 9.9 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EDN98651.1 - 0.024 14.7 0.2 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Atg14 PF10186.4 EDN98651.1 - 0.15 10.9 2.1 0.28 10.1 1.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-LITAF-like PF10601.4 EDN98652.1 - 6.5e-19 67.5 7.5 1.1e-18 66.8 5.2 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Mu-like_Com PF10122.4 EDN98652.1 - 0.0051 15.8 0.2 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Mu-like prophage protein Com TFIIA PF03153.8 EDN98652.1 - 9.1 6.0 14.7 14 5.4 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HATPase_c PF02518.21 EDN98653.1 - 7.4e-19 67.5 0.3 1.5e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.15 EDN98653.1 - 4.7e-17 61.7 0.0 9.6e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.21 EDN98653.1 - 6.1e-14 52.4 0.0 1.3e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 EDN98653.1 - 3.4e-12 46.3 0.0 1.4e-11 44.3 0.0 2.2 1 0 0 1 1 1 1 Response regulator receiver domain PAS_2 PF08446.6 EDN98653.1 - 2.5e-08 34.3 0.0 8e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EDN98653.1 - 0.005 17.2 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.1 EDN98653.1 - 0.011 15.3 0.2 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 EDN98653.1 - 0.062 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 PAS fold Pyridox_ox_2 PF12900.2 EDN98654.1 - 5.3e-18 65.2 0.0 1e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PTPA PF03095.10 EDN98656.1 - 4.3e-109 364.3 0.0 5.5e-109 363.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein OPT PF03169.10 EDN98658.1 - 5.8e-87 292.5 13.7 7.4e-87 292.2 9.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gly-zipper_Omp PF13488.1 EDN98658.1 - 0.072 12.7 0.2 0.072 12.7 0.1 3.3 4 0 0 4 4 4 0 Glycine zipper OPT PF03169.10 EDN98659.1 - 2.5e-49 168.2 4.8 3e-49 168.0 3.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5TM-5TMR_LYT PF07694.7 EDN98659.1 - 0.24 10.7 5.7 0.24 10.7 3.2 1.6 1 1 0 1 1 1 0 5TMR of 5TMR-LYT Methyltransf_31 PF13847.1 EDN98660.1 - 1e-13 51.1 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN98660.1 - 1.4e-12 47.3 0.0 3.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EDN98660.1 - 2.7e-12 47.2 0.0 6.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN98660.1 - 1.8e-10 41.1 0.0 5.8e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN98660.1 - 1.8e-09 37.6 0.0 3.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN98660.1 - 7e-08 32.7 0.0 1.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN98660.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDN98660.1 - 9.7e-07 28.1 0.0 1.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EDN98660.1 - 2.4e-06 27.0 0.1 4.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDN98660.1 - 4.8e-05 23.7 0.3 0.00013 22.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN98660.1 - 0.00017 20.7 0.1 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EDN98660.1 - 0.00019 20.2 0.0 0.00033 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EDN98660.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EDN98660.1 - 0.00077 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.11 EDN98660.1 - 0.00084 18.3 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 EDN98660.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EDN98660.1 - 0.0014 18.2 0.1 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EDN98660.1 - 0.0098 15.5 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.1 EDN98660.1 - 0.047 14.5 0.0 0.18 12.6 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EDN98660.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain WD40_alt PF14077.1 EDN98660.1 - 0.064 12.8 0.2 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif Mo25 PF08569.6 EDN98661.1 - 8.1e-115 383.4 5.4 8.5e-114 380.0 3.8 1.9 1 1 0 1 1 1 1 Mo25-like SWIB PF02201.13 EDN98662.1 - 2.6e-08 33.4 0.0 5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain adh_short PF00106.20 EDN98663.1 - 2.1e-09 37.5 0.1 2.3e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN98663.1 - 0.00024 20.8 0.1 0.00028 20.6 0.1 1.0 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDN98663.1 - 0.0071 16.1 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EDN98663.1 - 0.04 13.0 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EDN98663.1 - 0.062 13.3 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain Aida_C2 PF14186.1 EDN98663.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Cytoskeletal adhesion 3HCDH_N PF02737.13 EDN98663.1 - 0.14 11.7 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3012 PF11216.3 EDN98664.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) SAM_PNT PF02198.11 EDN98664.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Glyco_transf_28 PF03033.15 EDN98665.1 - 1.9e-21 76.2 0.0 4.7e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Pkinase PF00069.20 EDN98669.1 - 1.5e-63 214.4 0.0 1.9e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN98669.1 - 2.9e-30 105.2 0.0 4.2e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN98669.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN98669.1 - 0.0017 17.3 0.0 0.0037 16.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN98669.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.1 EDN98669.1 - 0.0077 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 PH domain tRNA-synt_1 PF00133.17 EDN98673.1 - 5.2e-175 582.8 0.5 8.3e-175 582.2 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDN98673.1 - 3.2e-26 91.9 0.0 1.2e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDN98673.1 - 2e-13 49.7 0.3 3e-07 29.4 0.1 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) Cmc1 PF08583.5 EDN98674.1 - 0.079 12.7 1.2 0.11 12.2 0.2 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sfi1 PF08457.5 EDN98675.1 - 1e-174 582.2 117.2 1e-174 582.1 70.2 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.3 EDN98677.1 - 7.9e-284 942.7 0.3 1.1e-283 942.1 0.2 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Methyltransf_31 PF13847.1 EDN98678.1 - 0.002 17.6 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FAM178 PF14816.1 EDN98681.1 - 0.091 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Pyridoxal_deC PF00282.14 EDN98681.1 - 0.096 11.1 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain RasGAP PF00616.14 EDN98682.1 - 1.2e-42 145.8 0.0 2.9e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EDN98682.1 - 0.00016 21.6 0.2 0.00052 19.9 0.1 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain XRN_N PF03159.13 EDN98683.1 - 1.4e-109 365.0 0.0 1.4e-109 365.0 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PS_pyruv_trans PF04230.8 EDN98683.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase UDPG_MGDP_dh_N PF03721.9 EDN98683.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-CCHC PF00098.18 EDN98683.1 - 0.65 10.0 4.7 1.2 9.1 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.9 EDN98684.1 - 2.4e-115 384.6 0.0 1.1e-114 382.4 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EDN98684.1 - 5.1e-09 36.1 26.1 5.1e-09 36.1 18.1 3.9 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Myosin_tail_1 PF01576.14 EDN98684.1 - 0.00062 17.6 37.7 0.00062 17.6 26.1 2.1 1 1 1 2 2 2 2 Myosin tail Reo_sigmaC PF04582.7 EDN98684.1 - 0.048 12.8 6.5 0.06 12.5 0.3 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein PcfJ PF14284.1 EDN98684.1 - 6.1 6.3 28.1 0.33 10.4 4.1 3.5 1 1 2 3 3 3 0 PcfJ-like protein Pinin_SDK_N PF04697.8 EDN98685.1 - 0.0023 17.9 0.1 0.0023 17.9 0.1 2.0 3 0 0 3 3 3 1 pinin/SDK conserved region Vfa1 PF08432.5 EDN98685.1 - 0.091 12.7 2.8 0.18 11.8 2.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NDUFA12 PF05071.11 EDN98686.1 - 6.7e-09 36.1 0.0 6.7e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3088 PF11287.3 EDN98689.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) zf-C2H2 PF00096.21 EDN98690.1 - 1.9e-10 40.4 15.9 0.00019 21.5 0.5 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN98690.1 - 2.4e-07 30.6 13.7 0.0017 18.5 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 EDN98690.1 - 0.012 15.3 1.3 0.035 13.8 0.9 1.9 1 0 0 1 1 1 0 BED zinc finger PyrI_C PF02748.10 EDN98690.1 - 0.068 12.6 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 EDN98690.1 - 0.49 10.5 4.4 6 7.0 0.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3724 PF12521.3 EDN98690.1 - 2.6 7.9 5.5 1 9.2 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) EPSP_synthase PF00275.15 EDN98691.1 - 3.9e-128 427.4 0.0 6.1e-128 426.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EDN98691.1 - 1.3e-101 338.9 0.0 2.7e-101 337.8 0.0 1.5 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EDN98691.1 - 8.8e-63 211.9 0.0 1.6e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EDN98691.1 - 1.6e-34 119.0 0.0 5.9e-33 113.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EDN98691.1 - 2.4e-23 81.9 0.0 6.5e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EDN98691.1 - 7.6e-13 48.7 0.0 2.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EDN98691.1 - 1.7e-08 34.0 0.0 3.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EDN98691.1 - 0.001 19.8 0.0 0.0035 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Pyr_redox_3 PF13738.1 EDN98691.1 - 0.091 12.8 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 EDN98693.1 - 2.9e-20 72.1 1.0 5.6e-20 71.2 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN98693.1 - 1.3e-05 25.0 0.1 2.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Hexapep PF00132.19 EDN98695.1 - 6.1e-11 41.3 2.8 3.2e-10 39.0 2.3 1.9 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN98695.1 - 7.6e-11 41.3 4.5 9.6e-11 41.0 2.2 1.8 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EDN98695.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Subtilosin_A PF11420.3 EDN98695.1 - 0.035 14.1 1.3 0.19 11.7 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin subtilosin A Asparaginase PF00710.15 EDN98696.1 - 0.024 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Asparaginase P3A PF08727.6 EDN98696.1 - 0.036 13.3 0.1 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like Cwf_Cwc_15 PF04889.7 EDN98698.1 - 4.9e-84 281.8 14.8 5.3e-84 281.7 10.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Tom37_C PF11801.3 EDN98698.1 - 0.2 11.5 2.8 0.3 10.9 2.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain HNF-1_N PF04814.8 EDN98698.1 - 0.82 9.7 6.8 1.2 9.2 4.0 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus GEMIN8 PF15348.1 EDN98698.1 - 1.2 9.1 8.4 1.4 8.8 5.8 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CDC27 PF09507.5 EDN98698.1 - 2.1 7.4 14.8 2.5 7.2 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 EDN98698.1 - 4.7 5.7 7.3 5.9 5.4 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNase_PH PF01138.16 EDN98699.1 - 1.4e-14 54.5 0.1 2.2e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDN98699.1 - 9.7e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Voltage_CLC PF00654.15 EDN98700.1 - 2.9e-93 312.7 24.6 4.7e-93 312.0 15.3 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 EDN98700.1 - 5.1 7.3 11.7 0.072 13.1 2.1 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Lipase_GDSL PF00657.17 EDN98701.1 - 6.5e-21 75.2 0.0 7.4e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDN98701.1 - 1.4e-20 74.1 0.0 1.7e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3876 PF12992.2 EDN98701.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF1039 PF06287.6 EDN98701.1 - 0.14 12.0 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) Isochorismatase PF00857.15 EDN98703.1 - 4.4e-19 69.0 0.0 7.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EDN98704.1 - 6.2e-79 264.6 1.3 1.1e-78 263.8 0.9 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EDN98704.1 - 4e-56 188.9 3.3 6.3e-56 188.3 2.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EDN98704.1 - 5.5e-05 22.5 1.7 0.0001 21.6 0.1 2.1 2 0 0 2 2 2 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.12 EDN98705.1 - 7e-41 138.8 0.1 1.3e-40 137.9 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EDN98705.1 - 4.2e-25 87.4 2.2 1.5e-24 85.7 1.5 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Ribosomal_S27e PF01667.12 EDN98705.1 - 0.028 13.9 0.4 0.052 13.0 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 Rib_recp_KP_reg PF05104.7 EDN98705.1 - 0.18 12.3 8.5 0.35 11.3 5.9 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region CDK2AP PF09806.4 EDN98705.1 - 0.79 9.9 4.7 7.7 6.7 3.3 2.2 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein HEAT PF02985.17 EDN98706.1 - 0.0051 16.7 4.9 2.7 8.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Nop14 PF04147.7 EDN98706.1 - 6 4.6 5.7 0.69 7.7 0.5 1.9 3 0 0 3 3 3 0 Nop14-like family TOM_sub5 PF15178.1 EDN98707.1 - 0.33 10.6 0.2 0.33 10.6 0.2 2.1 1 1 1 2 2 2 0 Mitochondrial import receptor subunit TOM5 homolog MBOAT PF03062.14 EDN98708.1 - 5.1e-19 68.5 17.7 8.3e-19 67.8 12.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EDN98708.1 - 0.0022 17.9 1.6 0.0075 16.3 1.1 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 EDN98709.1 - 3.9e-51 169.1 22.4 2.4e-09 36.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EDN98709.1 - 0.039 13.6 0.0 4.4 6.9 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EDN98709.1 - 0.071 11.8 0.1 0.2 10.3 0.1 1.8 2 1 0 2 2 2 0 Nup133 N terminal like Endonuclease_NS PF01223.18 EDN98710.1 - 1.7e-57 194.4 0.0 2.1e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 EDN98713.1 - 2.2e-29 102.4 17.0 1.5e-28 99.7 11.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4094 PF13334.1 EDN98713.1 - 0.078 13.3 0.0 0.078 13.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Lectin_leg-like PF03388.8 EDN98714.1 - 1.3e-63 214.2 0.1 1.7e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EDN98714.1 - 0.097 12.0 0.0 0.34 10.2 0.0 2.0 1 1 0 1 1 1 0 Legume lectin domain zf-Tim10_DDP PF02953.10 EDN98715.1 - 1.6e-24 84.9 3.5 1.9e-24 84.6 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4372 PF14294.1 EDN98715.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4372) DUF2116 PF09889.4 EDN98715.1 - 0.33 10.7 2.1 0.84 9.4 1.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2040 PF09745.4 EDN98716.1 - 1.8e-39 134.4 22.1 1.8e-39 134.4 15.3 2.9 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) TFIIE-A_C-term PF11521.3 EDN98717.1 - 0.048 13.6 2.7 0.085 12.8 1.0 2.2 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha OmpH PF03938.9 EDN98717.1 - 0.094 12.6 3.4 0.13 12.1 2.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FadA PF09403.5 EDN98717.1 - 3.7 7.5 12.1 8.6 6.3 8.0 1.9 2 0 0 2 2 2 0 Adhesion protein FadA Pkinase PF00069.20 EDN98718.1 - 2.9e-71 239.6 0.0 5.6e-71 238.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN98718.1 - 1.8e-39 135.3 0.0 3e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN98718.1 - 4.5e-07 29.1 0.1 9.4e-07 28.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN98718.1 - 0.019 14.6 0.0 0.077 12.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SOG2 PF10428.4 EDN98719.1 - 2.1 6.8 18.7 2.5 6.6 12.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Rifin_STEVOR PF02009.11 EDN98719.1 - 6 6.4 9.3 8.4 5.9 6.5 1.3 1 0 0 1 1 1 0 Rifin/stevor family SIN1 PF05422.7 EDN98721.1 - 2.4e-44 151.7 3.4 2.6e-20 72.4 0.0 3.7 3 1 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) GTP_cyclohydro2 PF00925.15 EDN98721.1 - 0.0019 17.4 0.0 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II TUG-UBL1 PF11470.3 EDN98721.1 - 0.0027 17.5 0.1 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 EDN98721.1 - 0.0034 17.0 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain PRCC PF10253.4 EDN98722.1 - 1.1e-43 149.9 0.8 1.1e-43 149.9 0.5 3.0 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3517 PF12030.3 EDN98724.1 - 1.1e-20 73.5 0.6 2.3e-18 65.8 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3517) UCH PF00443.24 EDN98724.1 - 4.1e-13 49.0 0.9 1.6e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EDN98725.1 - 3.4e-13 49.3 0.7 5.8e-13 48.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN98725.1 - 4.4e-07 29.6 0.6 9.7e-07 28.5 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CitG PF01874.11 EDN98725.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase RNase_P_pop3 PF08228.6 EDN98726.1 - 9.4e-16 58.0 0.0 4.6e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 RNase P subunit Pop3 DUF77 PF01910.12 EDN98727.1 - 7.7e-34 115.2 0.5 9.2e-34 114.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 PI-PLC-X PF00388.14 EDN98730.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Chorion_2 PF03964.10 EDN98730.1 - 3.4 8.2 12.4 0.056 13.9 2.4 2.4 3 0 0 3 3 3 0 Chorion family 2 Acetyltransf_1 PF00583.19 EDN98731.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family HlyIII PF03006.15 EDN98733.1 - 9.3e-21 74.2 5.9 1.1e-20 74.0 4.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2029 PF09594.5 EDN98733.1 - 0.076 12.4 3.5 0.13 11.7 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) DUF3397 PF11877.3 EDN98733.1 - 0.23 11.4 2.5 0.33 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) AAA PF00004.24 EDN98735.1 - 3.9e-15 56.2 0.0 8.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN98735.1 - 0.00079 19.4 0.0 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN98735.1 - 0.0034 17.5 0.1 0.045 13.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN98735.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 EDN98735.1 - 0.012 15.0 0.1 1.9 7.8 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EDN98735.1 - 0.02 15.6 1.0 0.25 12.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EDN98735.1 - 0.029 13.4 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EDN98735.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN98735.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1900 PF08954.6 EDN98736.1 - 1.4e-48 163.8 0.0 7.8e-48 161.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EDN98736.1 - 9.5e-35 118.0 0.3 1.9e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EDN98736.1 - 7.6e-27 92.1 0.1 2.6e-08 33.4 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EDN98736.1 - 0.0018 16.5 0.2 0.18 9.9 0.1 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF730 PF05325.6 EDN98736.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) AA_permease PF00324.16 EDN98739.1 - 2e-112 376.0 43.5 3.6e-112 375.1 30.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN98739.1 - 4.2e-28 98.0 46.7 1.6e-27 96.1 32.4 1.7 1 1 0 1 1 1 1 Amino acid permease YfiO PF13525.1 EDN98742.1 - 0.021 14.3 0.9 0.12 11.7 0.6 2.0 1 1 0 1 1 1 0 Outer membrane lipoprotein HtaA PF04213.8 EDN98746.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 Htaa CTD_bind PF04818.8 EDN98749.1 - 2.9e-21 75.4 0.2 5.4e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 EDN98749.1 - 0.012 15.1 0.1 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) LepA_C PF06421.7 EDN98749.1 - 0.064 13.1 0.1 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus CTK3 PF12243.3 EDN98749.1 - 0.07 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.12 EDN98750.1 - 1.6e-74 250.6 9.6 1.8e-74 250.4 6.7 1.0 1 0 0 1 1 1 1 Clathrin light chain Virulence_RhuM PF13310.1 EDN98750.1 - 0.05 12.5 3.8 0.074 12.0 2.6 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family rve_3 PF13683.1 EDN98750.1 - 0.061 12.8 0.3 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4407 PF14362.1 EDN98750.1 - 6.3 5.6 7.1 3.9 6.3 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CDC37_N PF03234.9 EDN98751.1 - 1.7e-55 188.1 4.3 1.7e-55 188.1 3.0 2.8 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EDN98751.1 - 5.6e-45 152.9 1.0 1.5e-44 151.5 0.7 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EDN98751.1 - 1.7e-25 88.7 0.4 1.7e-25 88.7 0.3 2.8 2 1 1 3 3 3 1 Cdc37 C terminal domain ABC_membrane PF00664.18 EDN98752.1 - 2.3e-42 145.2 11.4 3.1e-42 144.8 7.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDN98752.1 - 3e-36 124.7 0.0 1.1e-35 122.9 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EDN98752.1 - 2e-05 23.9 0.1 0.00076 18.7 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN98752.1 - 0.00012 22.1 0.3 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN98752.1 - 0.0016 17.9 0.1 0.004 16.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN98752.1 - 0.0076 16.2 0.2 0.031 14.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN98752.1 - 0.027 14.6 0.5 0.19 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EDN98752.1 - 0.028 14.3 0.6 0.22 11.4 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EDN98752.1 - 0.03 15.1 0.2 0.12 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EDN98752.1 - 0.038 12.5 0.1 0.038 12.5 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NUDE_C PF04880.8 EDN98760.1 - 0.017 15.4 2.3 0.021 15.2 1.1 1.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Rpn3_C PF08375.6 EDN98760.1 - 0.082 13.3 1.0 0.18 12.2 0.1 1.9 1 1 1 2 2 2 0 Proteasome regulatory subunit C-terminal Histone PF00125.19 EDN98766.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDN98766.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDN98766.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN98766.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDN98766.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EDN98766.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sedlin_N PF04628.8 EDN98768.1 - 6.2e-35 119.9 0.0 7e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EDN98768.1 - 0.00042 20.0 0.0 0.013 15.2 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family L31 PF09784.4 EDN98769.1 - 7.8e-46 154.3 2.7 8.7e-46 154.2 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.16 EDN98769.1 - 0.028 14.9 1.6 0.035 14.6 1.1 1.2 1 0 0 1 1 1 0 H-NS histone family P22_Cro PF14549.1 EDN98769.1 - 0.038 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Val_tRNA-synt_C PF10458.4 EDN98769.1 - 0.12 12.5 0.7 0.93 9.6 0.5 2.2 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.17 EDN98770.1 - 1.8e-15 56.2 0.0 2.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN98770.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98770.1 - 2.2e-08 33.7 0.1 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDN98771.1 - 0.042 13.7 0.5 0.23 11.4 0.3 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat FliT PF05400.8 EDN98771.1 - 0.45 10.9 6.9 0.097 13.0 1.0 2.5 2 1 0 2 2 2 0 Flagellar protein FliT zf-CCCH PF00642.19 EDN98772.1 - 6.7e-05 22.4 17.5 0.0015 18.1 1.2 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDN98772.1 - 0.06 13.3 14.0 0.37 10.8 2.4 3.1 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type tRNA-synt_1b PF00579.20 EDN98773.1 - 1e-21 77.3 0.0 3.7e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_S10 PF00450.17 EDN98774.1 - 2.4e-91 306.9 0.0 3.2e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3328 PF11807.3 EDN98776.1 - 0.014 15.1 5.9 3.7 7.1 4.1 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF1049 PF06305.6 EDN98776.1 - 0.098 12.1 1.9 0.16 11.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3328 PF11807.3 EDN98777.1 - 1.1e-53 182.1 1.0 1.6e-53 181.6 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Vps4_C PF09336.5 EDN98778.1 - 4e-06 26.6 7.1 0.54 10.1 0.0 5.5 1 1 6 7 7 7 3 Vps4 C terminal oligomerisation domain DUF3779 PF12621.3 EDN98778.1 - 0.0026 17.6 19.5 13 5.7 0.4 8.2 1 1 6 8 8 8 2 Phosphate metabolism protein RALF PF05498.6 EDN98778.1 - 0.18 12.6 0.2 93 3.9 0.0 4.8 2 2 3 6 6 6 0 Rapid ALkalinization Factor (RALF) DUF1103 PF06513.6 EDN98778.1 - 1.9 7.8 7.9 3.1 7.1 3.5 2.4 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) MFS_1 PF07690.11 EDN98779.1 - 1.9e-05 23.5 5.3 1.9e-05 23.5 3.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN98779.1 - 0.003 16.2 3.9 0.0048 15.5 2.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter WT1 PF02165.10 EDN98779.1 - 0.083 11.9 0.1 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Wilm's tumour protein FSH1 PF03959.8 EDN98780.1 - 1.5e-30 106.2 0.0 2.7e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDN98780.1 - 5.4e-07 29.4 0.0 7.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN98780.1 - 1.3e-06 28.5 0.3 3.2e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDN98780.1 - 4.5e-06 26.2 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EDN98780.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Pyr_redox_3 PF13738.1 EDN98781.1 - 1.1e-20 74.5 0.0 2.9e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN98781.1 - 3e-15 55.4 0.0 7.9e-15 54.0 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDN98781.1 - 1.5e-07 31.3 0.0 4.5e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDN98781.1 - 7.7e-07 28.3 0.3 2.4e-05 23.4 0.0 3.0 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN98781.1 - 2e-06 27.8 0.0 0.0009 19.1 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN98781.1 - 0.0042 16.1 0.3 0.023 13.7 0.0 2.2 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EDN98781.1 - 0.0077 15.1 0.0 0.33 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN98781.1 - 0.012 15.4 0.2 4.3 7.0 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EDN98781.1 - 0.34 9.9 1.0 0.52 9.3 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain AMP-binding PF00501.23 EDN98782.1 - 1.9e-81 273.6 0.0 2.8e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EDN98782.1 - 2.5e-73 246.6 0.0 4.7e-73 245.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDN98782.1 - 4.3e-38 131.4 0.0 1e-37 130.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 EDN98782.1 - 7e-37 126.8 0.0 1.7e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EDN98782.1 - 6.4e-26 90.5 0.1 4.5e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EDN98782.1 - 8.9e-14 51.5 0.7 9.5e-07 29.0 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EDN98782.1 - 4.2e-12 46.2 0.0 1.8e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 HxxPF-repeated domain Thiolase_N PF00108.18 EDN98782.1 - 5.8e-06 25.4 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PS-DH PF14765.1 EDN98782.1 - 2.1e-05 23.8 0.0 4.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase rve PF00665.21 EDN98784.1 - 2.4e-08 34.1 0.1 6.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN98784.1 - 7.2e-05 22.3 0.3 0.0002 20.9 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Saccharop_dh PF03435.13 EDN98787.1 - 6e-21 74.8 0.1 8.4e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EDN98787.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDN98787.1 - 0.051 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EDN98787.1 - 0.083 12.5 0.1 0.43 10.2 0.1 2.0 2 0 0 2 2 2 0 KR domain Ribosomal_L37ae PF01780.14 EDN98788.1 - 5.6e-40 135.1 9.5 6.2e-40 134.9 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EDN98788.1 - 0.00059 19.5 2.6 0.00093 18.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EDN98788.1 - 0.005 16.2 3.6 0.015 14.7 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Sgf11 PF08209.6 EDN98788.1 - 0.048 12.9 0.3 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) OrfB_Zn_ribbon PF07282.6 EDN98788.1 - 0.12 12.0 1.2 0.18 11.5 0.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.6 EDN98788.1 - 0.19 11.5 0.8 0.26 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Elf1 PF05129.8 EDN98788.1 - 0.24 11.0 2.8 0.41 10.3 2.0 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EDN98788.1 - 0.32 10.7 6.3 5.3 6.8 0.4 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EDN98788.1 - 0.69 9.9 4.1 1.2 9.1 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 EDN98788.1 - 2 8.9 4.8 2.8 8.4 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type CarbpepA_inh PF02977.10 EDN98788.1 - 2 8.0 5.8 25 4.5 4.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.1 EDN98788.1 - 2.2 8.7 7.8 1 9.7 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain MAGUK_N_PEST PF10608.4 EDN98789.1 - 0.17 12.3 4.6 0.085 13.2 0.4 2.4 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK DUF605 PF04652.11 EDN98790.1 - 3.1 7.1 6.7 3.5 6.9 4.7 1.2 1 0 0 1 1 1 0 Vta1 like PHF5 PF03660.9 EDN98791.1 - 3.6e-51 171.7 10.0 4e-51 171.5 6.9 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EDN98791.1 - 1.1 9.0 15.6 8.6 6.2 1.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EDN98791.1 - 1.2 8.9 15.4 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Pinin_SDK_memA PF04696.8 EDN98792.1 - 2.4e-08 33.6 12.6 2.4e-08 33.6 8.7 3.2 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 EDN98793.1 - 3e-31 109.0 0.0 4.3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN98793.1 - 2.8e-19 69.5 0.0 1e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN98793.1 - 6.5e-13 48.6 0.0 1.5e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EDN98793.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PHD PF00628.24 EDN98796.1 - 1.1e-09 37.7 7.7 1.1e-09 37.7 5.3 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EDN98796.1 - 1.1e-07 31.5 4.7 1.1e-07 31.5 3.3 4.2 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EDN98796.1 - 4.7e-06 26.6 16.8 1.4e-05 25.0 3.2 3.4 3 0 0 3 3 3 2 RING-H2 zinc finger PHD_2 PF13831.1 EDN98796.1 - 8.1e-06 25.0 3.6 8.1e-06 25.0 2.5 1.9 2 0 0 2 2 1 1 PHD-finger zf-Apc11 PF12861.2 EDN98796.1 - 0.00012 21.8 10.7 0.00038 20.2 0.6 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EDN98796.1 - 0.00078 19.0 3.7 0.00078 19.0 2.6 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN98796.1 - 0.00092 18.8 3.1 0.00092 18.8 2.2 3.8 4 0 0 4 4 4 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EDN98796.1 - 0.0036 17.0 6.2 0.0036 17.0 4.3 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 EDN98796.1 - 0.0063 16.1 6.2 0.0063 16.1 4.3 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN98796.1 - 0.012 15.5 4.4 0.012 15.5 3.0 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 EDN98796.1 - 0.15 11.3 8.4 0.014 14.6 2.0 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_4 PF14447.1 EDN98796.1 - 0.33 10.5 4.9 0.75 9.3 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 EDN98796.1 - 0.38 10.5 8.1 16 5.4 5.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon MRP-L46 PF11788.3 EDN98797.1 - 1.1e-30 106.5 0.1 2.4e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EDN98797.1 - 0.055 13.1 0.3 0.14 11.7 0.2 1.8 1 1 0 1 1 1 0 NUDIX domain DAO PF01266.19 EDN98798.1 - 3.4e-16 59.1 0.0 2.7e-11 42.9 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase KH_4 PF13083.1 EDN98798.1 - 0.027 14.1 0.4 0.058 13.0 0.3 1.5 1 0 0 1 1 1 0 KH domain NAD_binding_9 PF13454.1 EDN98798.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Aminotran_1_2 PF00155.16 EDN98799.1 - 9.2e-40 136.7 0.0 1.1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CTV_P13 PF06922.6 EDN98799.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Citrus tristeza virus P13 protein ABC2_membrane PF01061.19 EDN98800.1 - 4.4e-93 310.2 47.3 2.4e-50 170.6 10.8 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EDN98800.1 - 6.2e-41 139.9 0.0 3.1e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EDN98800.1 - 2.5e-28 97.7 3.8 1e-27 95.8 0.0 3.1 3 0 0 3 3 3 1 CDR ABC transporter ABC_trans_N PF14510.1 EDN98800.1 - 2.8e-09 36.9 0.2 7.3e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EDN98800.1 - 1.6e-08 33.9 37.8 0.00018 20.6 5.9 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EDN98800.1 - 5e-07 29.3 0.2 0.0063 15.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN98800.1 - 3.7e-05 23.8 0.2 0.22 11.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDN98800.1 - 0.00012 21.3 0.1 0.0059 15.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EDN98800.1 - 0.00072 19.0 1.3 0.37 10.2 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EDN98800.1 - 0.00079 20.2 0.0 2 9.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDN98800.1 - 0.0013 18.7 0.3 0.094 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EDN98800.1 - 0.0027 17.2 0.9 1.6 8.1 0.2 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EDN98800.1 - 0.0031 16.9 1.1 0.082 12.4 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDN98800.1 - 0.0037 17.1 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EDN98800.1 - 0.0068 16.3 1.9 0.52 10.2 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDN98800.1 - 0.012 15.6 0.0 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EDN98800.1 - 0.016 14.9 0.5 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EDN98800.1 - 0.018 14.6 0.5 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EDN98800.1 - 0.02 15.1 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EDN98800.1 - 0.021 14.4 1.0 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EDN98800.1 - 0.065 12.9 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EDN98800.1 - 0.069 13.3 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EDN98800.1 - 0.099 13.1 0.0 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 EDN98800.1 - 0.17 11.1 0.3 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_30 PF13604.1 EDN98800.1 - 4.8 6.7 5.1 14 5.1 0.2 2.7 3 0 0 3 3 2 0 AAA domain Lectin_leg-like PF03388.8 EDN98801.1 - 3.1e-30 104.9 0.0 5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Pox_Ag35 PF03286.9 EDN98801.1 - 0.0075 15.8 2.4 0.013 15.0 1.7 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF1515 PF07439.6 EDN98801.1 - 0.016 14.9 0.4 0.032 14.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Phage_GPO PF05929.6 EDN98801.1 - 0.022 14.0 0.3 0.022 14.0 0.2 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 EDN98801.1 - 0.031 14.0 7.3 0.25 11.1 1.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 EDN98801.1 - 0.079 11.3 4.2 0.12 10.8 2.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.4 EDN98801.1 - 0.081 13.0 0.2 0.081 13.0 0.2 2.4 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.8 EDN98801.1 - 0.091 12.1 0.7 0.2 11.0 0.5 1.6 1 0 0 1 1 1 0 fzo-like conserved region Reo_sigmaC PF04582.7 EDN98801.1 - 0.1 11.7 4.9 0.24 10.5 2.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EDN98801.1 - 0.29 10.9 1.8 2 8.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMCO5 PF14992.1 EDN98801.1 - 0.39 9.8 4.1 0.65 9.0 2.9 1.3 1 0 0 1 1 1 0 TMCO5 family GrpE PF01025.14 EDN98801.1 - 1.5 8.3 8.4 3.6 7.1 5.8 1.6 1 1 0 1 1 1 0 GrpE IncA PF04156.9 EDN98801.1 - 6.4 6.3 20.3 79 2.7 14.1 2.2 1 1 0 1 1 1 0 IncA protein Alg6_Alg8 PF03155.10 EDN98802.1 - 1.6e-136 455.8 25.7 1.9e-136 455.6 17.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EDN98803.1 - 5.8e-39 132.3 0.0 1.8e-38 130.8 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EDN98803.1 - 1.7e-18 66.1 2.4 3.1e-18 65.2 1.7 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EDN98803.1 - 7.5e-14 51.0 0.4 1.8e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EDN98803.1 - 0.0071 16.2 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 IncA PF04156.9 EDN98803.1 - 6.2 6.3 15.9 5.4 6.5 0.6 2.6 1 1 1 2 2 2 0 IncA protein CCDC-167 PF15188.1 EDN98803.1 - 8 6.4 11.3 1.1 9.2 0.4 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 YL1 PF05764.8 EDN98804.1 - 1.1e-58 198.6 23.3 1.1e-58 198.6 16.1 2.4 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EDN98804.1 - 3.3e-13 48.9 0.7 5.8e-13 48.1 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 EDN98807.1 - 3.9e-28 95.3 0.0 6.3e-05 22.2 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EDN98807.1 - 2.8e-10 39.6 0.0 5.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN98807.1 - 2.2e-06 27.5 0.0 6.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98807.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.16 EDN98810.1 - 2.1e-85 287.2 0.0 2.5e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Amidase SLAIN PF15301.1 EDN98811.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family MFS_1 PF07690.11 EDN98812.1 - 3.5e-25 88.4 83.7 1.7e-21 76.3 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CAF1 PF04857.15 EDN98813.1 - 1.9e-49 168.4 0.1 3.8e-49 167.3 0.2 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EDN98813.1 - 0.0036 16.7 0.1 0.041 13.3 0.0 2.4 2 0 0 2 2 2 1 3'-5' exonuclease MAP7 PF05672.6 EDN98814.1 - 0.0023 17.3 20.0 0.0059 16.0 13.8 1.7 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Herpes_DNAp_acc PF04929.7 EDN98814.1 - 0.0034 16.4 0.0 0.069 12.1 0.0 2.6 2 1 0 2 2 2 1 Herpes DNA replication accessory factor MFS_1 PF07690.11 EDN98815.1 - 9.3e-31 106.8 16.7 1.3e-27 96.4 2.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EDN98815.1 - 0.00057 18.7 1.3 0.01 14.5 0.0 2.2 2 0 0 2 2 2 2 BT1 family Mem_trans PF03547.13 EDN98815.1 - 0.01 14.1 0.3 0.016 13.4 0.0 1.5 2 0 0 2 2 2 0 Membrane transport protein OATP PF03137.15 EDN98815.1 - 0.011 13.7 1.1 0.26 9.2 0.7 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SCA7 PF08313.7 EDN98816.1 - 8.4e-31 105.4 2.3 1.4e-30 104.6 0.9 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-C2HC_2 PF13913.1 EDN98816.1 - 0.1 12.3 0.7 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Herpes_LMP1 PF05297.6 EDN98816.1 - 0.22 10.4 2.0 0.41 9.5 1.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CDC45 PF02724.9 EDN98816.1 - 0.76 7.7 5.8 0.93 7.4 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDE_1 PF03184.14 EDN98817.1 - 7.3e-44 149.4 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN98817.1 - 3.8e-08 33.1 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_CI_repr PF07022.8 EDN98817.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain zf-CCHC PF00098.18 EDN98817.1 - 0.018 14.9 7.3 0.035 14.0 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle SNF5 PF04855.7 EDN98818.1 - 1.6e-71 240.6 0.1 2.7e-71 239.8 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 EDN98819.1 - 1.3e-08 34.6 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EDN98820.1 - 1.1e-05 25.0 2.2 1.1e-05 25.0 1.6 2.6 2 1 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 EDN98820.1 - 0.11 11.8 0.3 0.26 10.5 0.2 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain HEAT PF02985.17 EDN98822.1 - 3.4e-07 29.8 4.7 0.051 13.6 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 EDN98822.1 - 3.4e-07 30.4 3.8 0.00018 21.7 0.3 5.0 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EDN98822.1 - 0.0028 18.0 4.2 0.11 13.0 0.1 4.2 4 0 0 4 4 4 1 HEAT-like repeat DUF4487 PF14868.1 EDN98822.1 - 0.054 12.2 0.9 0.12 11.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) FA_desaturase PF00487.19 EDN98824.1 - 3.4e-29 102.0 20.0 5.6e-29 101.3 13.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EDN98824.1 - 8.6e-06 25.8 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Meth_synt_2 PF01717.13 EDN98824.1 - 0.032 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain HTH_psq PF05225.11 EDN98826.1 - 1.5e-11 43.6 0.3 1.9e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN98826.1 - 0.0011 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NUMOD1 PF07453.8 EDN98826.1 - 0.028 14.2 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 NUMOD1 domain HTH_28 PF13518.1 EDN98826.1 - 0.033 14.1 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN98826.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain zf-C2H2_4 PF13894.1 EDN98827.1 - 0.0022 18.2 7.5 0.069 13.5 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger IL5 PF02025.10 EDN98828.1 - 0.079 12.9 0.7 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Interleukin 5 Ubiq_cyt_C_chap PF03981.7 EDN98829.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Clr5 PF14420.1 EDN98836.1 - 1.8e-18 66.1 0.2 5.6e-18 64.5 0.1 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EDN98836.1 - 4e-09 36.2 5.1 0.00095 19.0 0.3 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDN98836.1 - 4.7e-05 22.9 5.1 0.02 14.8 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN98836.1 - 6.6e-05 22.9 1.4 0.0064 16.5 0.2 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDN98836.1 - 0.00021 21.0 0.1 0.093 12.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN98836.1 - 0.00065 19.9 0.2 3.6 8.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN98836.1 - 0.0007 19.0 9.0 0.037 13.6 1.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN98836.1 - 0.0054 16.4 2.9 3.2 7.7 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN98836.1 - 0.0058 17.1 0.3 49 4.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDN98836.1 - 0.0072 15.9 1.3 0.037 13.6 0.6 2.5 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EDN98836.1 - 0.017 14.8 7.4 0.11 12.2 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EDN98836.1 - 0.038 14.0 0.3 0.16 12.0 0.0 2.2 3 0 0 3 3 2 0 Tetratrico peptide repeat mRNA_cap_enzyme PF01331.14 EDN98839.1 - 5.8e-49 166.3 0.1 9.1e-49 165.7 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EDN98839.1 - 7.5e-25 87.2 0.2 1.4e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EDN98839.1 - 6.9e-07 28.8 0.4 2.8e-05 23.5 0.2 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNase_H PF00075.19 EDN98840.1 - 3.1e-15 56.6 0.1 5.6e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 RNase H GnsAB PF08178.6 EDN98840.1 - 0.016 14.8 0.1 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 GnsA/GnsB family FumaraseC_C PF10415.4 EDN98840.1 - 0.072 13.1 0.6 0.57 10.2 0.4 2.2 2 0 0 2 2 2 0 Fumarase C C-terminus Sirohm_synth_C PF14823.1 EDN98841.1 - 0.075 12.3 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Sec3_C_2 PF15278.1 EDN98842.1 - 0.063 13.4 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 Sec3 exocyst complex subunit Tim17 PF02466.14 EDN98843.1 - 8.4e-27 93.7 2.8 1e-26 93.4 2.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 EDN98844.1 - 1.8e-48 164.7 0.9 7.1e-32 110.4 0.0 2.9 2 1 1 3 3 3 2 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EDN98844.1 - 0.00025 20.8 3.2 15 5.9 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EDN98844.1 - 0.001 19.5 0.2 1.1 9.8 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat Cna_B PF05738.8 EDN98846.1 - 0.06 13.1 0.3 5.4 6.8 0.0 2.9 3 0 0 3 3 3 0 Cna protein B-type domain CHORD PF04968.7 EDN98846.1 - 0.76 10.0 7.6 6.6 7.0 1.6 2.2 2 0 0 2 2 2 0 CHORD Acyltransferase PF01553.16 EDN98847.1 - 9.8e-14 50.9 0.0 3.3e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 EDN98848.1 - 1.5e-08 34.5 13.7 1.1e-05 25.3 2.9 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN98848.1 - 9.8e-07 28.4 14.6 2e-06 27.3 4.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN98848.1 - 2.5e-06 27.2 11.9 0.00015 21.4 2.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.1 EDN98848.1 - 2.3e-05 24.0 3.3 2.3e-05 24.0 2.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EDN98848.1 - 3e-05 23.5 15.9 6.3e-05 22.5 4.5 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN98848.1 - 5.5e-05 22.7 15.3 0.0023 17.5 4.0 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EDN98848.1 - 0.00026 20.8 6.2 0.00026 20.8 4.3 2.8 2 2 0 2 2 2 1 FYVE zinc finger Rtf2 PF04641.7 EDN98848.1 - 0.0017 17.5 6.7 0.0017 17.5 4.7 2.5 1 1 2 3 3 3 1 Rtf2 RING-finger Vps39_2 PF10367.4 EDN98848.1 - 0.0041 17.2 2.1 0.0041 17.2 1.5 2.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.1 EDN98848.1 - 0.24 11.3 17.7 2.5 8.0 1.3 3.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EDN98848.1 - 0.92 9.3 15.1 6.6 6.6 5.4 3.4 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 EDN98848.1 - 1.2 8.7 11.9 7.3 6.2 2.9 3.3 3 0 0 3 3 3 0 Ribosomal protein S27 Rad50_zn_hook PF04423.9 EDN98848.1 - 1.4 8.3 0.0 1.4 8.3 0.0 3.2 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF4428 PF14471.1 EDN98848.1 - 1.8 8.3 6.4 12 5.7 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) DUF566 PF04484.7 EDN98850.1 - 0.029 13.9 0.5 0.034 13.6 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2365 PF10157.4 EDN98850.1 - 0.03 14.2 1.0 0.036 13.9 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) 3H PF02829.9 EDN98850.1 - 0.13 12.2 1.5 0.18 11.8 1.1 1.2 1 0 0 1 1 1 0 3H domain BLOC1_2 PF10046.4 EDN98850.1 - 0.16 12.0 5.0 0.14 12.3 1.0 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 EDN98850.1 - 0.23 11.2 10.3 0.24 11.2 6.7 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Syntaxin_2 PF14523.1 EDN98850.1 - 0.42 10.6 4.4 0.49 10.4 3.1 1.1 1 0 0 1 1 1 0 Syntaxin-like protein DUF1409 PF07197.7 EDN98850.1 - 0.48 10.5 7.1 1.3 9.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) NPV_P10 PF05531.7 EDN98850.1 - 0.83 9.9 3.4 4.3 7.6 2.4 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 EDN98850.1 - 1 8.8 13.7 1.1 8.7 9.5 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zein-binding PF04576.10 EDN98850.1 - 1.4 9.0 10.6 2.1 8.5 7.4 1.3 1 0 0 1 1 1 0 Zein-binding Atg14 PF10186.4 EDN98850.1 - 1.7 7.4 5.1 2 7.3 3.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V-SNARE PF05008.10 EDN98850.1 - 2.2 8.5 7.5 0.6 10.3 1.8 2.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Phage_Gp23 PF10669.4 EDN98850.1 - 3.5 7.7 6.1 1.8 8.7 0.5 2.0 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) OmpH PF03938.9 EDN98850.1 - 4.5 7.1 9.7 9.8 6.0 6.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GnsAB PF08178.6 EDN98851.1 - 0.041 13.5 0.3 0.096 12.3 0.2 1.6 1 0 0 1 1 1 0 GnsA/GnsB family DUF3592 PF12158.3 EDN98852.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Mito_carr PF00153.22 EDN98853.1 - 2.8e-49 164.7 0.0 8.8e-17 60.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 EDN98853.1 - 0.00078 19.8 9.7 0.001 19.4 1.3 3.4 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF883) INTS5_N PF14837.1 EDN98853.1 - 0.16 11.3 1.8 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DivIVA PF05103.8 EDN98853.1 - 0.49 10.4 15.1 0.12 12.4 4.2 2.7 2 1 0 2 2 2 0 DivIVA protein Prominin PF05478.6 EDN98853.1 - 0.72 7.3 5.7 0.99 6.8 2.9 1.7 1 1 0 1 1 1 0 Prominin She9_MDM33 PF05546.6 EDN98853.1 - 1.1 8.7 7.1 0.23 10.9 0.1 2.4 2 1 1 3 3 3 0 She9 / Mdm33 family DUF4363 PF14276.1 EDN98853.1 - 7.7 6.2 7.0 3 7.5 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DNA_ligase_A_M PF01068.16 EDN98854.1 - 1.7e-57 194.0 0.6 4.9e-46 156.6 0.1 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDN98854.1 - 1.6e-51 174.6 2.2 9e-51 172.1 0.1 2.4 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDN98854.1 - 8e-28 96.6 0.0 2.9e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region tRNA-synt_2 PF00152.15 EDN98855.1 - 9.3e-55 185.7 0.0 1.7e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN98855.1 - 4.8e-08 32.7 0.0 9.2e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipoprotein_16 PF03923.8 EDN98855.1 - 0.023 14.0 2.1 0.026 13.8 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized lipoprotein Prefoldin PF02996.12 EDN98856.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit RRM_6 PF14259.1 EDN98857.1 - 5.9e-37 125.4 0.0 3.7e-08 33.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN98857.1 - 1.1e-36 124.3 0.0 1.1e-11 44.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN98857.1 - 8.9e-18 63.8 0.0 0.00024 20.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EDN98857.1 - 1.7e-12 46.7 7.7 1.7e-12 46.7 5.3 2.8 2 1 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EDN98857.1 - 0.00012 21.8 0.1 0.059 13.2 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EDN98857.1 - 0.41 10.6 3.8 0.78 9.7 0.0 3.1 4 0 0 4 4 4 0 RNA binding domain DDE_1 PF03184.14 EDN98858.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN98858.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN98858.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98858.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN98858.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EDN98859.1 - 1.1e-47 162.0 0.0 3.3e-47 160.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN98859.1 - 8.7e-13 48.2 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98859.1 - 5.4e-11 42.1 0.2 1.8e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain rve PF00665.21 EDN98859.1 - 0.011 15.7 0.0 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain PX PF00787.19 EDN98860.1 - 6.4e-20 71.0 0.0 2.5e-19 69.1 0.0 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EDN98860.1 - 4.2e-14 52.3 8.9 2.2e-07 30.3 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Mcm10 PF09332.6 EDN98860.1 - 0.0027 17.1 7.0 0.0051 16.2 4.8 1.4 1 0 0 1 1 1 1 Mcm10 replication factor Sugar_tr PF00083.19 EDN98861.1 - 1.1e-102 343.9 26.2 2.1e-68 230.9 4.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN98861.1 - 7.9e-13 47.8 36.6 2.9e-09 36.1 11.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4646 PF15496.1 EDN98864.1 - 6.7e-05 22.9 0.3 0.00028 20.9 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) Zn_clus PF00172.13 EDN98865.1 - 3.8e-10 39.5 10.8 7.3e-10 38.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chordopox_A13L PF05961.6 EDN98865.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Arginase PF00491.16 EDN98866.1 - 3.9e-93 311.7 0.0 4.6e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EDN98866.1 - 0.027 14.6 1.2 0.066 13.4 0.3 1.8 1 1 1 2 2 2 0 UPF0489 domain Ras PF00071.17 EDN98867.1 - 1.9e-52 176.8 0.0 2.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN98867.1 - 2.8e-16 60.0 0.0 9.1e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN98867.1 - 2.2e-07 30.3 0.0 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Fungal_trans PF04082.13 EDN98870.1 - 7e-21 74.2 0.6 1e-20 73.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3623 PF12291.3 EDN98873.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Inhibitor_I67 PF11405.3 EDN98873.1 - 4.7 7.3 28.6 5.3 7.1 0.6 5.7 5 0 0 5 5 5 0 Bromelain inhibitor VI RNase_H PF00075.19 EDN98874.1 - 2.2e-06 28.0 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN98874.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Sugar_tr PF00083.19 EDN98875.1 - 2.1e-90 303.4 12.4 2.4e-90 303.2 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN98875.1 - 1.3e-15 56.9 12.8 1.8e-15 56.5 8.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 EDN98875.1 - 0.082 12.8 0.2 0.082 12.8 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Ferritin_2 PF13668.1 EDN98877.1 - 1.3e-14 54.3 0.0 2.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain PNPOx_C PF10590.4 EDN98880.1 - 1.3e-21 75.8 1.9 3.8e-21 74.3 1.3 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EDN98880.1 - 7.4e-18 64.3 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EDN98880.1 - 0.0012 19.1 0.2 0.0022 18.2 0.1 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Imm45 PF15603.1 EDN98880.1 - 0.083 13.0 0.2 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 Immunity protein 45 Peptidase_M35 PF02102.10 EDN98882.1 - 8.9e-108 360.1 20.1 1.2e-107 359.7 14.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EDN98882.1 - 1.2e-05 25.8 1.1 2.6e-05 24.7 0.8 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.6 EDN98882.1 - 0.062 13.3 2.4 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 CARDB Paramyxo_C PF01692.13 EDN98884.1 - 1.3 8.6 4.0 1.6 8.3 2.8 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Dicty_REP PF05086.7 EDN98884.1 - 2.5 5.7 7.3 2.8 5.5 5.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EMP70 PF02990.11 EDN98886.1 - 2.9e-164 547.3 3.2 1.2e-163 545.3 2.2 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 EDN98886.1 - 5.3 6.1 13.3 1.9 7.6 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Pex2_Pex12 PF04757.9 EDN98887.1 - 1.9e-52 177.9 6.8 2.3e-52 177.6 4.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EDN98887.1 - 2.3e-06 27.5 3.4 4.1e-06 26.6 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDN98887.1 - 9.6e-06 25.3 3.2 1.7e-05 24.6 2.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDN98887.1 - 8.4e-05 22.3 2.8 0.00015 21.5 1.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN98887.1 - 0.004 16.8 1.3 0.0062 16.1 0.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN98887.1 - 0.004 16.7 3.1 0.0066 16.0 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDN98887.1 - 0.082 12.6 0.8 0.29 10.8 0.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Ribonuclease_3 PF00636.21 EDN98888.1 - 3.8e-24 85.3 0.1 4.9e-16 59.1 0.0 4.2 2 1 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 EDN98888.1 - 5.6e-19 67.7 1.5 3.8e-18 65.0 0.0 3.0 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.26 EDN98888.1 - 1.3e-16 60.2 0.0 4e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.1 EDN98888.1 - 5.4e-16 58.7 0.0 5.4e-06 26.3 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like dsrm PF00035.20 EDN98888.1 - 0.0028 18.1 0.1 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif ResIII PF04851.10 EDN98888.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EDN98888.1 - 0.033 13.4 0.1 0.075 12.3 0.1 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain DEAD PF00270.24 EDN98888.1 - 0.038 13.4 0.0 0.089 12.2 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase TAP42 PF04177.7 EDN98889.1 - 1.5e-107 359.5 0.0 1.7e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Zn_clus PF00172.13 EDN98891.1 - 1.5e-08 34.3 7.1 1.5e-08 34.3 4.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_Coat_A PF05357.8 EDN98891.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage Coat Protein A Fib_alpha PF08702.5 EDN98894.1 - 0.0011 19.1 3.9 0.0011 19.1 2.7 8.7 6 2 3 10 10 10 5 Fibrinogen alpha/beta chain family CN_hydrolase PF00795.17 EDN98895.1 - 1.6e-37 128.6 0.0 2.1e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF612 PF04747.7 EDN98899.1 - 0.016 14.1 0.2 0.019 13.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 CAF1-p150_C2 PF15539.1 EDN98902.1 - 0.33 10.0 2.9 0.38 9.8 2.0 1.0 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term AIF-MLS PF14962.1 EDN98902.1 - 3.5 7.2 6.8 4.5 6.8 4.7 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence NOA36 PF06524.7 EDN98902.1 - 5.7 6.0 8.2 6.5 5.9 5.7 1.1 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.17 EDN98903.1 - 2.2e-58 197.7 6.6 5.9e-58 196.3 4.6 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter FtsX PF02687.16 EDN98903.1 - 3.5 7.4 10.9 0.31 10.7 1.1 2.9 2 1 1 3 3 3 0 FtsX-like permease family Peptidase_C12 PF01088.16 EDN98904.1 - 1e-58 198.0 0.0 1.2e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2215 PF10225.4 EDN98908.1 - 0.093 12.1 0.3 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) E1-E2_ATPase PF00122.15 EDN98909.1 - 1.6e-66 223.6 0.5 1.6e-66 223.6 0.3 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EDN98909.1 - 3.3e-23 83.2 0.1 3e-22 80.1 0.0 2.5 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN98909.1 - 2.8e-12 47.1 0.0 7.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN98909.1 - 2.3e-09 36.5 0.0 5.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN98909.1 - 0.0043 16.6 0.1 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN98909.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Chorion_S16 PF05836.7 EDN98910.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Chorion protein S16 Fungal_trans_2 PF11951.3 EDN98913.1 - 9.9e-12 44.1 5.1 1e-10 40.7 3.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_1 PF00300.17 EDN98918.1 - 9.8e-09 35.4 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MOSC_N PF03476.11 EDN98919.1 - 9.3e-19 67.3 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EDN98919.1 - 2.4e-14 52.9 0.0 3.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain DUF2036 PF09724.4 EDN98920.1 - 6.7e-05 22.1 0.4 8.1e-05 21.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) NARG2_C PF10505.4 EDN98920.1 - 0.048 12.8 0.1 0.23 10.6 0.0 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RhoGEF PF00621.15 EDN98921.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain MSC PF09402.5 EDN98922.1 - 0.015 13.9 0.9 0.027 13.1 0.6 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TPR_MLP1_2 PF07926.7 EDN98922.1 - 5.9 6.6 16.3 1.5 8.5 6.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IBR PF01485.16 EDN98923.1 - 0.0034 17.2 9.8 0.0034 17.2 6.8 3.7 2 1 1 3 3 3 2 IBR domain Acetyltransf_7 PF13508.1 EDN98925.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HORMA PF02301.13 EDN98926.1 - 1.5e-22 80.1 0.0 2.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 EDN98927.1 - 1.2e-10 41.1 0.2 7.9e-10 38.5 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EDN98927.1 - 0.003 17.4 0.1 0.07 13.0 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein DUF1205 PF06722.7 EDN98929.1 - 0.011 16.0 0.4 2.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1205) Fungal_trans PF04082.13 EDN98930.1 - 3.1e-21 75.4 0.8 5.1e-21 74.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN98930.1 - 7e-07 29.0 8.6 1.3e-06 28.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF21 PF01595.15 EDN98931.1 - 0.028 13.7 0.2 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF21 AzlC PF03591.9 EDN98931.1 - 0.67 9.8 3.5 0.85 9.5 0.1 2.6 3 1 1 4 4 4 0 AzlC protein FAD_binding_3 PF01494.14 EDN98935.1 - 1.2e-05 24.5 0.0 0.042 12.8 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Amino_oxidase PF01593.19 EDN98935.1 - 0.0048 16.0 0.0 0.0065 15.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EDN98935.1 - 0.039 14.3 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YvrJ PF12841.2 EDN98936.1 - 0.045 13.0 0.5 0.11 11.7 0.3 1.6 1 0 0 1 1 1 0 YvrJ protein family TPR_MLP1_2 PF07926.7 EDN98936.1 - 0.064 13.0 0.1 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Peptidase_A17 PF05380.8 EDN98937.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Pao retrotransposon peptidase PI31_Prot_N PF11566.3 EDN98938.1 - 1.8e-37 128.3 0.0 2.2e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EDN98938.1 - 1.8e-18 66.9 18.3 1.8e-18 66.9 12.7 2.3 2 1 0 2 2 2 1 PI31 proteasome regulator CRAL_TRIO PF00650.15 EDN98939.1 - 3.5e-23 81.8 0.0 5.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain MoCF_biosynth PF00994.19 EDN98940.1 - 2.5e-23 82.0 0.0 5.7e-23 80.9 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EDN98942.1 - 4.2e-59 198.5 0.2 4.9e-59 198.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN98942.1 - 6e-19 68.7 0.0 8.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN98942.1 - 1.4e-08 34.2 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN98942.1 - 9.5e-08 31.6 0.2 4.4e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN98942.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN98942.1 - 0.0034 16.6 0.0 0.0054 16.0 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN98942.1 - 0.018 14.2 0.2 0.11 11.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EDN98942.1 - 0.027 13.6 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2075 PF09848.4 EDN98942.1 - 0.075 11.9 0.1 1.1 8.1 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zn_clus PF00172.13 EDN98943.1 - 0.011 15.5 8.3 0.011 15.5 5.7 4.3 4 1 1 5 5 5 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EDN98943.1 - 0.072 11.1 3.4 0.16 9.9 2.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EDN98943.1 - 9.8 5.6 8.8 17 4.9 6.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin adh_short PF00106.20 EDN98946.1 - 8.4e-31 107.1 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN98946.1 - 1.8e-11 44.0 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN98946.1 - 2.4e-10 40.6 0.0 3.1e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN98946.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EDN98946.1 - 0.11 11.3 0.1 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DDE_1 PF03184.14 EDN98948.1 - 7.4e-10 38.3 0.0 6.9e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98948.1 - 1.9e-09 37.1 0.0 3.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Glyco_hydro_15 PF00723.16 EDN98949.1 - 8.7e-80 268.4 0.0 1e-79 268.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EDN98949.1 - 5.3e-24 83.6 0.2 1.2e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain TPR_MLP1_2 PF07926.7 EDN98951.1 - 0.17 11.5 10.2 1.3 8.7 5.9 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 EDN98951.1 - 1 8.4 16.2 0.56 9.2 2.6 2.9 2 2 0 2 2 2 0 Tropomyosin Epimerase PF01370.16 EDN98952.1 - 1e-10 41.4 0.0 2e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN98952.1 - 1.5e-05 24.0 0.0 4.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EDN98952.1 - 0.015 14.0 0.0 0.03 13.0 0.0 1.6 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EDN98952.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 KR domain GLTP PF08718.6 EDN98953.1 - 5.8e-45 152.9 0.0 7.3e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Methyltransf_10 PF05971.7 EDN98955.1 - 3.7e-20 72.2 0.3 4.7e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_10 PF05971.7 EDN98956.1 - 5.7e-21 74.9 0.6 8.8e-12 44.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF890) Macro PF01661.16 EDN98957.1 - 3.9e-40 136.4 0.1 1.3e-39 134.7 0.0 1.8 2 0 0 2 2 2 1 Macro domain tRNA-synt_1c PF00749.16 EDN98958.1 - 7.6e-99 330.3 0.0 1.3e-98 329.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDN98958.1 - 1.1e-27 96.8 0.0 5e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.11 EDN98959.1 - 1.6e-33 115.8 36.3 1.2e-30 106.4 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDN98959.1 - 0.044 11.9 11.4 0.004 15.4 4.6 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HET PF06985.6 EDN98960.1 - 2.5e-37 128.1 0.1 5.2e-37 127.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DDE_1 PF03184.14 EDN98961.1 - 1.1e-52 178.3 0.0 1.8e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN98961.1 - 3.2e-07 30.0 0.1 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN98961.1 - 1.4e-06 28.0 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN98961.1 - 0.016 15.1 7.3 0.043 13.7 5.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Dynamin_N PF00350.18 EDN98962.1 - 1e-11 44.9 0.0 1e-11 44.9 0.0 3.5 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EDN98962.1 - 1.5e-05 24.9 0.0 0.00035 20.5 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDN98962.1 - 0.00016 20.8 0.0 0.01 15.0 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDN98962.1 - 0.0014 18.9 1.1 0.0038 17.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter PRK PF00485.13 EDN98962.1 - 0.0052 16.3 1.9 1 8.9 0.0 3.2 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 EDN98962.1 - 0.013 15.9 0.0 0.077 13.4 0.0 2.4 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EDN98962.1 - 0.046 13.7 0.0 0.35 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF4140 PF13600.1 EDN98962.1 - 0.83 10.1 8.5 8 6.9 2.1 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EDN98962.1 - 2.8 7.4 15.5 4.1 6.9 0.1 3.6 2 1 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EDN98962.1 - 3.6 7.9 11.8 0.77 10.1 1.4 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EDN98962.1 - 9.5 3.9 11.6 8.1 4.1 6.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EDN98962.1 - 9.9 6.1 9.4 34 4.4 0.0 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UBA PF00627.26 EDN98963.1 - 0.00013 21.7 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain Cellulase PF00150.13 EDN98964.1 - 1.3e-26 93.4 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PPE PF00823.14 EDN98964.1 - 0.2 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 PPE family Ldh_1_N PF00056.18 EDN98965.1 - 1.5e-43 148.0 0.1 3.3e-43 146.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDN98965.1 - 7.7e-40 136.4 0.1 1.2e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EDN98965.1 - 0.0055 15.4 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA PF00004.24 EDN98968.1 - 1e-14 54.8 1.9 1.2e-14 54.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDN98968.1 - 0.00015 21.4 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EDN98968.1 - 0.0019 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN98968.1 - 0.0027 17.8 3.4 0.0064 16.6 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN98968.1 - 0.0091 16.8 0.0 0.0091 16.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDN98968.1 - 0.27 11.2 4.8 0.16 11.9 0.2 2.7 2 1 1 3 3 3 0 AAA ATPase domain Syja_N PF02383.13 EDN98969.1 - 0.12 11.1 0.1 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 SacI homology domain DUF3837 PF12939.2 EDN98970.1 - 0.052 13.5 0.3 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DLIC PF05783.6 EDN98970.1 - 0.074 11.7 0.2 0.17 10.5 0.1 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) HTH_Tnp_Tc5 PF03221.11 EDN98971.1 - 1e-12 47.6 0.6 3.2e-12 46.0 0.0 2.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN98971.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDN98971.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain DUF3450 PF11932.3 EDN98972.1 - 0.017 14.3 0.2 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3373 PF11853.3 EDN98972.1 - 0.051 12.1 0.6 0.051 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CoA_trans PF01144.18 EDN98972.1 - 0.11 11.6 0.1 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Coenzyme A transferase ABC_tran PF00005.22 EDN98973.1 - 2.6e-47 160.5 1.9 1.5e-23 83.6 0.0 3.9 3 2 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EDN98973.1 - 1.1e-18 67.2 0.1 1.7e-06 27.4 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN98973.1 - 1.9e-17 64.1 0.2 0.00057 19.9 0.0 4.5 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EDN98973.1 - 1.1e-09 37.6 0.1 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN98973.1 - 1.4e-08 35.3 10.9 9.9e-05 22.7 0.0 3.9 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 EDN98973.1 - 2e-08 33.6 0.2 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN98973.1 - 4.1e-08 33.4 0.0 0.00041 20.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EDN98973.1 - 5.1e-08 33.7 0.0 0.0043 17.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDN98973.1 - 9e-08 31.5 1.2 0.095 11.7 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.18 EDN98973.1 - 3e-07 30.4 0.0 0.00016 21.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EDN98973.1 - 3.1e-07 30.3 0.0 0.0032 17.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EDN98973.1 - 3.4e-07 30.3 0.1 0.0042 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDN98973.1 - 1.7e-06 27.9 0.0 0.099 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EDN98973.1 - 4.4e-06 27.1 0.1 0.027 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EDN98973.1 - 6.7e-06 26.4 0.5 0.21 11.8 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EDN98973.1 - 1.4e-05 24.7 0.2 0.26 10.6 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain SbcCD_C PF13558.1 EDN98973.1 - 1.9e-05 24.4 0.0 0.092 12.6 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EDN98973.1 - 2.3e-05 24.1 0.1 0.27 10.9 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDN98973.1 - 2.6e-05 24.4 0.0 0.33 11.1 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EDN98973.1 - 3.3e-05 22.7 0.1 0.2 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EDN98973.1 - 4.2e-05 23.6 0.0 0.6 10.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase HEAT_2 PF13646.1 EDN98973.1 - 5.8e-05 23.2 1.3 0.76 10.1 1.7 3.2 2 1 1 3 3 2 2 HEAT repeats Arch_ATPase PF01637.13 EDN98973.1 - 0.00011 22.0 0.8 0.43 10.2 0.0 3.4 5 0 0 5 5 2 2 Archaeal ATPase AAA_16 PF13191.1 EDN98973.1 - 0.00023 21.1 1.3 1.1 9.2 0.0 4.1 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.7 EDN98973.1 - 0.00029 20.5 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EDN98973.1 - 0.00038 20.3 0.1 1.2 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EDN98973.1 - 0.0004 19.8 0.0 0.84 9.1 0.0 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Cnd1 PF12717.2 EDN98973.1 - 0.0019 18.0 0.0 0.22 11.3 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ATP-synt_ab PF00006.20 EDN98973.1 - 0.002 17.6 0.2 2 7.8 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 EDN98973.1 - 0.0021 16.6 8.8 0.97 7.8 0.0 4.4 4 1 0 4 4 4 1 AAA domain cobW PF02492.14 EDN98973.1 - 0.0024 17.3 0.0 1.4 8.3 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain V-ATPase_H_C PF11698.3 EDN98973.1 - 0.0042 17.0 1.3 0.013 15.4 0.9 1.8 1 0 0 1 1 1 1 V-ATPase subunit H MutS_V PF00488.16 EDN98973.1 - 0.005 16.2 0.1 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V AAA_25 PF13481.1 EDN98973.1 - 0.006 16.0 0.0 5.9 6.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EDN98973.1 - 0.0062 16.1 0.1 5.1 6.6 0.0 3.2 4 0 0 4 4 2 0 AAA domain DUF87 PF01935.12 EDN98973.1 - 0.0095 15.7 3.2 1 9.1 0.0 3.5 3 1 0 3 3 2 1 Domain of unknown function DUF87 Mg_chelatase PF01078.16 EDN98973.1 - 0.014 14.5 0.1 2 7.5 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 EDN98973.1 - 0.018 14.1 0.5 2.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Septin Rad17 PF03215.10 EDN98973.1 - 0.02 13.6 0.0 2 7.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 EDN98973.1 - 0.021 14.3 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EDN98973.1 - 0.022 14.2 0.1 6.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adaptin_N PF01602.15 EDN98973.1 - 0.029 12.7 3.3 0.13 10.5 0.4 2.4 1 1 1 2 2 2 0 Adaptin N terminal region DUF3502 PF12010.3 EDN98973.1 - 0.032 14.2 1.3 0.07 13.1 0.1 2.2 3 0 0 3 3 1 0 Domain of unknown function (DUF3502) NB-ARC PF00931.17 EDN98973.1 - 0.032 13.0 0.4 0.31 9.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EDN98973.1 - 0.034 13.6 0.1 4.1 6.8 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arm_2 PF04826.8 EDN98973.1 - 0.034 13.2 0.4 1.1 8.3 0.3 2.8 3 0 0 3 3 3 0 Armadillo-like HEAT_EZ PF13513.1 EDN98973.1 - 0.075 13.5 4.8 12 6.5 0.0 5.0 6 0 0 6 6 4 0 HEAT-like repeat HEAT PF02985.17 EDN98973.1 - 0.086 12.9 3.6 0.28 11.3 0.0 3.5 4 0 0 4 4 2 0 HEAT repeat T2SE PF00437.15 EDN98973.1 - 0.12 11.2 2.6 4.1 6.2 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein DAP3 PF10236.4 EDN98973.1 - 1.5 7.7 6.1 16 4.3 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 zf-C2H2_4 PF13894.1 EDN98974.1 - 0.0055 16.9 18.6 0.14 12.6 0.1 5.2 4 1 1 5 5 5 2 C2H2-type zinc finger zf-TFIIB PF13453.1 EDN98974.1 - 0.12 11.5 4.1 3.7 6.8 0.2 3.5 3 1 0 3 3 3 0 Transcription factor zinc-finger RRN7 PF11781.3 EDN98974.1 - 0.12 11.8 6.0 2.5 7.6 0.0 3.8 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 EDN98974.1 - 0.35 11.2 0.1 0.35 11.2 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EDN98974.1 - 0.37 11.2 0.1 0.37 11.2 0.1 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN98977.1 - 3.6e-11 42.5 5.9 4.1e-05 23.6 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN98977.1 - 5.2e-11 42.2 8.8 2e-05 24.6 1.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EDN98977.1 - 2e-09 36.7 0.2 4.3e-09 35.6 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 EDN98977.1 - 6.1e-06 26.2 4.2 0.042 14.0 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN98977.1 - 1.2e-05 25.3 3.7 0.052 13.7 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EDN98977.1 - 2.4e-05 24.3 1.3 2.4e-05 24.3 0.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDN98977.1 - 0.004 17.0 5.0 0.38 10.7 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDN98977.1 - 0.19 11.8 3.1 4.9 7.3 0.1 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 EDN98978.1 - 8.8e-25 86.3 20.4 2.7e-12 46.3 3.6 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EDN98978.1 - 0.0096 15.7 3.6 0.0096 15.7 2.5 2.6 2 1 0 2 2 2 2 IBR domain DUF3415 PF11895.3 EDN98978.1 - 0.011 15.6 0.5 5.4 6.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3415) Transp_Tc5_C PF04236.10 EDN98978.1 - 0.015 15.5 14.4 0.22 11.7 2.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 EDN98978.1 - 2.1 8.3 15.3 5.5 7.0 1.2 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain SGL PF08450.7 EDN98981.1 - 1.2e-28 100.1 0.0 3.7e-28 98.5 0.0 1.7 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EDN98981.1 - 0.00044 20.1 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EDN98981.1 - 0.0016 18.4 0.0 0.0084 16.1 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase Reg_prop PF07494.6 EDN98981.1 - 0.17 11.9 1.0 2.8 8.2 0.0 3.4 4 0 0 4 4 4 0 Two component regulator propeller NHL PF01436.16 EDN98981.1 - 0.28 11.2 2.8 14 5.8 0.0 3.5 3 0 0 3 3 3 0 NHL repeat DDE_1 PF03184.14 EDN98982.1 - 2.4e-07 30.0 0.0 3.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Herpes_BLRF2 PF05812.7 EDN98982.1 - 0.78 9.5 4.0 5.4 6.8 0.1 2.8 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EDN98982.1 - 2 8.4 5.7 0.43 10.5 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor PTR2 PF00854.16 EDN98985.1 - 4.1e-39 134.4 4.8 6.7e-39 133.7 3.3 1.4 1 1 0 1 1 1 1 POT family NAD_binding_10 PF13460.1 EDN98987.1 - 1.2e-15 57.9 0.0 2.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN98987.1 - 1.7e-09 37.2 0.0 1.3e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EDN98987.1 - 0.0049 16.3 0.0 0.034 13.5 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.4 EDN98987.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 PAC2 family adh_short PF00106.20 EDN98987.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_3 PF13738.1 EDN98988.1 - 1.3e-15 57.9 0.0 1.8e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN98988.1 - 3.1e-13 48.7 0.0 4.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDN98988.1 - 8.1e-07 28.9 0.0 2.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN98988.1 - 1.3e-06 28.4 0.0 3.6e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN98988.1 - 3.3e-06 26.9 0.1 5.6e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EDN98988.1 - 0.0038 15.7 0.2 0.0056 15.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EDN98988.1 - 0.0061 15.6 0.3 0.013 14.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 EDN98988.1 - 0.017 14.0 0.1 0.14 10.9 0.0 2.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EDN98988.1 - 0.027 14.8 0.3 7.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN98988.1 - 0.041 12.9 0.3 0.074 12.1 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EDN98988.1 - 0.069 11.9 0.4 0.1 11.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 EDN98988.1 - 0.071 12.1 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF3328 PF11807.3 EDN98990.1 - 1.4e-50 171.9 2.5 1.7e-50 171.7 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_membrane PF00664.18 EDN98992.1 - 4e-58 197.0 29.7 3.2e-31 108.7 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDN98992.1 - 3.8e-56 189.1 0.1 4.9e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter M20_dimer PF07687.9 EDN98992.1 - 7.9e-20 70.6 0.1 1.6e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA_29 PF13555.1 EDN98992.1 - 1.7e-10 40.2 1.0 0.00058 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Peptidase_M20 PF01546.23 EDN98992.1 - 2.2e-10 40.3 0.2 6e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AAA_17 PF13207.1 EDN98992.1 - 9.1e-09 36.1 0.0 0.00046 20.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EDN98992.1 - 3.1e-08 33.9 6.4 0.0084 16.0 0.1 3.6 2 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN98992.1 - 1e-07 31.4 4.8 0.001 18.3 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN98992.1 - 1.1e-07 32.0 0.4 0.0019 18.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EDN98992.1 - 5.6e-07 28.8 0.1 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN98992.1 - 1.3e-06 28.5 0.2 0.12 12.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDN98992.1 - 6.6e-06 26.4 0.0 0.074 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN98992.1 - 1.5e-05 25.4 3.8 0.018 15.3 0.4 3.0 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 EDN98992.1 - 7e-05 22.7 0.6 0.21 11.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_30 PF13604.1 EDN98992.1 - 0.0003 20.4 0.0 0.16 11.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EDN98992.1 - 0.0003 20.3 2.2 0.13 11.6 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain ABC_ATPase PF09818.4 EDN98992.1 - 0.00053 18.6 0.1 0.058 11.9 0.0 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 EDN98992.1 - 0.00095 18.8 0.0 0.36 10.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EDN98992.1 - 0.001 18.9 0.2 0.65 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EDN98992.1 - 0.0051 16.5 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EDN98992.1 - 0.0054 16.2 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EDN98992.1 - 0.0058 16.1 0.3 2.1 7.8 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EDN98992.1 - 0.0062 16.2 0.1 0.54 9.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EDN98992.1 - 0.0062 15.6 1.3 0.87 8.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EDN98992.1 - 0.0081 15.5 0.0 5.4 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDN98992.1 - 0.0098 15.3 0.0 0.064 12.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDN98992.1 - 0.01 15.7 0.5 0.45 10.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EDN98992.1 - 0.016 15.1 0.3 0.84 9.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EDN98992.1 - 0.017 14.5 0.3 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EDN98992.1 - 0.021 14.8 1.8 6.9 6.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.1 EDN98992.1 - 0.025 13.1 0.1 1.1 7.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 EDN98992.1 - 0.037 14.2 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EDN98992.1 - 0.063 12.9 0.5 13 5.4 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase G-alpha PF00503.15 EDN98992.1 - 0.097 11.3 0.1 4.2 5.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.7 EDN98992.1 - 0.18 10.8 0.0 0.87 8.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PLDc_2 PF13091.1 EDN98993.1 - 1.9e-18 66.4 0.0 6.1e-14 51.8 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDN98993.1 - 0.00013 21.6 0.1 0.0036 17.0 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif MCM PF00493.18 EDN98994.1 - 2.2e-136 454.0 0.9 3e-136 453.5 0.6 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN98994.1 - 8.1e-20 71.5 0.1 4.6e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN98994.1 - 8.7e-08 31.5 0.0 8.3e-07 28.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDN98994.1 - 0.001 18.5 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDN98994.1 - 0.0016 18.0 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN98994.1 - 0.0076 15.9 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF4385 PF14328.1 EDN98995.1 - 8.8e-12 45.1 0.8 8.8e-12 45.1 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4385) RNase_H2_suC PF08615.6 EDN98996.1 - 7.8e-29 100.2 0.0 9.1e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EDN98997.1 - 1.6e-71 240.5 0.0 3.9e-71 239.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDN98997.1 - 1e-11 44.7 0.0 2e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN98997.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN98997.1 - 2.8e-10 40.7 0.0 5.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN98997.1 - 9.7e-07 28.4 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN98997.1 - 6.6e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN98997.1 - 1.6e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EDN98997.1 - 0.018 14.5 0.0 0.21 11.1 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_3 PF01596.12 EDN98997.1 - 0.027 13.5 0.0 0.079 12.0 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase PCMT PF01135.14 EDN98997.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2877 PF11392.3 EDN98997.1 - 0.087 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) RNase_T PF00929.19 EDN98998.1 - 8.5e-26 91.1 0.0 1.8e-25 90.1 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EDN98998.1 - 0.0096 15.4 0.0 0.029 13.8 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.13 EDN98999.1 - 3.9e-86 287.1 0.4 6e-86 286.5 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EDN98999.1 - 2.5e-18 65.5 0.0 1.3e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EDN98999.1 - 0.039 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN98999.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_hydro_45 PF02015.11 EDN99000.1 - 2.2e-85 285.8 20.9 2.2e-85 285.8 14.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 Peptidase_M35 PF02102.10 EDN99000.1 - 2 6.9 22.0 2.9 6.4 2.6 2.3 2 0 0 2 2 2 0 Deuterolysin metalloprotease (M35) family F-box PF00646.28 EDN99003.1 - 0.017 14.7 0.3 0.042 13.5 0.2 1.7 1 0 0 1 1 1 0 F-box domain PRANC PF09372.5 EDN99003.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.2 EDN99003.1 - 0.054 13.2 2.3 0.069 12.8 0.2 2.3 2 0 0 2 2 2 0 F-box-like p450 PF00067.17 EDN99004.1 - 3.1e-50 171.0 0.0 3.9e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Staphylokinase PF02821.11 EDN99004.1 - 0.032 14.0 1.6 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family His_Phos_2 PF00328.17 EDN99004.1 - 0.099 11.9 1.3 0.25 10.6 0.9 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) GFA PF04828.9 EDN99005.1 - 3.8e-10 39.5 1.4 5.2e-10 39.1 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme OB_NTP_bind PF07717.11 EDN99006.1 - 3.9e-29 100.7 0.0 4.8e-28 97.2 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN99006.1 - 9.1e-27 93.0 0.1 3.1e-26 91.3 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN99006.1 - 6.3e-12 45.1 0.0 1.6e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EDN99006.1 - 1.9e-09 37.5 2.1 4.1e-09 36.3 1.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EDN99006.1 - 7e-07 28.8 0.1 1.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN99006.1 - 2.8e-05 24.2 0.2 0.0001 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDN99006.1 - 9.2e-05 22.0 0.1 0.0037 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDN99006.1 - 0.00015 20.8 0.0 0.00041 19.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EDN99006.1 - 0.0057 16.3 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EDN99006.1 - 0.075 13.3 0.2 1.8 8.8 0.0 2.6 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.1 EDN99006.1 - 0.097 12.5 0.1 0.87 9.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain ETC_C1_NDUFA4 PF04800.7 EDN99008.1 - 8.5e-38 128.2 1.7 1.2e-37 127.7 1.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EDN99009.1 - 5.2e-37 125.9 0.4 6e-37 125.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EDN99009.1 - 0.047 13.7 0.1 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Aminotran_1_2 PF00155.16 EDN99011.1 - 6.5e-14 51.6 0.0 1.5e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDN99011.1 - 0.0036 15.9 0.0 0.046 12.2 0.0 2.5 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase Glyco_hydro_16 PF00722.16 EDN99012.1 - 1.5e-10 40.7 0.2 6.9e-10 38.5 0.0 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_C12 PF01088.16 EDN99013.1 - 7.3e-49 165.8 0.0 1e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Mito_carr PF00153.22 EDN99016.1 - 4.6e-57 189.7 0.0 3.1e-20 71.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Hamartin PF04388.7 EDN99016.1 - 7.8e-45 153.7 28.4 3.4e-44 151.6 19.6 2.1 1 1 0 1 1 1 1 Hamartin protein CRT10 PF08728.5 EDN99016.1 - 2.1 6.2 13.8 2.9 5.7 9.6 1.1 1 0 0 1 1 1 0 CRT10 DLH PF01738.13 EDN99017.1 - 6.4e-29 100.8 0.0 7.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDN99017.1 - 1.2e-07 31.6 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L23 PF00276.15 EDN99018.1 - 5.5e-13 48.6 0.0 9.4e-13 47.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 KilA-N PF04383.8 EDN99018.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 KilA-N domain MT-A70 PF05063.9 EDN99019.1 - 2.4e-30 105.3 0.3 1.5e-20 73.4 0.1 2.3 2 0 0 2 2 2 2 MT-A70 COesterase PF00135.23 EDN99021.1 - 6.2e-48 163.8 0.0 6.6e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family HCV_NS5a_C PF12941.2 EDN99022.1 - 0.014 15.0 0.2 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region ICL PF00463.16 EDN99022.1 - 0.028 12.6 0.0 0.04 12.1 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Zn_clus PF00172.13 EDN99022.1 - 0.093 12.6 2.5 0.16 11.8 1.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UL73_N PF12522.3 EDN99024.1 - 0.14 11.7 9.7 0.16 11.4 6.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal NADH_dehy_S2_C PF06444.6 EDN99024.1 - 0.17 12.1 1.6 0.18 12.0 1.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus SR-25 PF10500.4 EDN99024.1 - 0.26 10.7 7.0 0.26 10.7 4.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NmrA PF05368.8 EDN99025.1 - 5.7e-26 91.2 0.0 7.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN99025.1 - 1e-05 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN99025.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN99025.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_holin_5 PF06946.6 EDN99028.1 - 0.13 12.4 0.9 0.16 12.1 0.6 1.2 1 0 0 1 1 1 0 Phage holin Exo_endo_phos_2 PF14529.1 EDN99030.1 - 1.5e-22 79.4 1.5 4.7e-22 77.8 1.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN99030.1 - 1.5e-06 28.3 0.2 2.5e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EFF-AFF PF14884.1 EDN99035.1 - 0.1 10.6 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Grp1_Fun34_YaaH PF01184.14 EDN99039.1 - 5.6e-29 100.9 20.9 8.5e-29 100.3 14.5 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2614 PF11023.3 EDN99039.1 - 2.2 8.1 10.5 0.065 13.0 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) MFS_1 PF07690.11 EDN99046.1 - 2.1e-37 128.6 45.1 2.1e-37 128.6 31.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2304 PF10066.4 EDN99046.1 - 0.086 12.6 5.4 0.079 12.8 0.5 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) 4HBT_2 PF13279.1 EDN99047.1 - 2.3e-08 34.5 0.0 3.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TMEM52 PF14979.1 EDN99047.1 - 0.012 15.4 0.0 0.84 9.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane 52 ELO PF01151.13 EDN99048.1 - 2.7e-61 207.0 19.5 3.2e-61 206.8 13.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p450 PF00067.17 EDN99049.1 - 2e-76 257.3 0.0 2.3e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EDN99051.1 - 1.4e-21 76.5 0.0 1.7e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Transferase family Coprogen_oxidas PF01218.13 EDN99051.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase p450 PF00067.17 EDN99052.1 - 3.7e-47 160.9 0.0 1.1e-46 159.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EDN99056.1 - 9.8e-49 166.0 46.6 1.2e-48 165.7 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN99056.1 - 5e-23 81.1 40.9 6.5e-23 80.8 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease Plant_vir_prot PF01307.12 EDN99056.1 - 0.34 10.6 1.9 51 3.6 0.0 3.6 3 0 0 3 3 3 0 Plant viral movement protein YoqO PF14037.1 EDN99057.1 - 0.38 10.8 5.1 0.45 10.6 2.6 1.7 2 0 0 2 2 2 0 YoqO-like protein Methyltransf_11 PF08241.7 EDN99058.1 - 5.3e-12 46.0 0.0 1.4e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN99058.1 - 5.1e-11 42.3 0.0 9e-11 41.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN99058.1 - 8.6e-11 42.4 0.0 1.8e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN99058.1 - 4e-10 39.6 0.0 1e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN99058.1 - 5e-08 33.3 0.0 9.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EDN99058.1 - 7.4e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 EDN99058.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EDN99058.1 - 3.1e-06 27.4 0.1 5.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN99058.1 - 1.4e-05 25.0 0.1 5.8e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EDN99058.1 - 0.0001 21.5 0.0 0.00021 20.5 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EDN99058.1 - 0.00014 21.0 0.0 0.00028 20.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EDN99058.1 - 0.00032 19.8 0.0 0.00044 19.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0146 PF03686.8 EDN99058.1 - 0.00047 19.9 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) MTS PF05175.9 EDN99058.1 - 0.00093 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EDN99058.1 - 0.00098 19.1 0.1 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EDN99058.1 - 0.0013 17.8 0.0 0.0033 16.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 EDN99058.1 - 0.0029 16.5 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme FmrO PF07091.6 EDN99058.1 - 0.0047 15.9 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EDN99058.1 - 0.005 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EDN99058.1 - 0.0082 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EDN99058.1 - 0.0091 15.4 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.13 EDN99058.1 - 0.031 13.4 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase 3HCDH_N PF02737.13 EDN99058.1 - 0.043 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_32 PF13679.1 EDN99058.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EDN99058.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pro-kuma_activ PF09286.6 EDN99062.1 - 8.5e-40 136.1 0.1 1.3e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN99062.1 - 1.9e-08 33.8 0.0 4e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Subtilase family p450 PF00067.17 EDN99063.1 - 8.3e-68 228.9 0.0 1.1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 EDN99064.1 - 3.2e-29 100.3 0.1 1.6e-21 75.6 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN99064.1 - 4.2e-20 71.5 0.0 1.7e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN99064.1 - 3.2e-16 58.8 0.0 1.4e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN99064.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NDUFB10 PF10249.4 EDN99065.1 - 0.00056 20.0 0.0 0.00066 19.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Pyr_excise PF03013.9 EDN99065.1 - 0.039 13.7 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase HWE_HK PF07536.9 EDN99065.1 - 0.081 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.5 EDN99066.1 - 3.4e-26 90.6 0.7 3.1e-20 71.5 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 Retinal PF15449.1 EDN99066.1 - 6.5 4.2 17.2 11 3.5 11.9 1.3 1 0 0 1 1 1 0 Retinal protein TAFII55_N PF04658.8 EDN99067.1 - 2.9e-51 173.1 0.0 5.2e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF4094 PF13334.1 EDN99067.1 - 0.017 15.4 0.5 0.046 14.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4391 PF14335.1 EDN99067.1 - 0.079 12.3 3.0 0.13 11.6 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) MraY_sig1 PF10555.4 EDN99067.1 - 0.081 12.2 1.9 0.3 10.4 1.3 2.0 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 FlxA PF14282.1 EDN99067.1 - 0.84 9.6 12.0 0.046 13.6 4.5 1.7 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 EDN99067.1 - 0.9 9.0 9.5 0.051 13.1 2.2 2.0 2 0 0 2 2 2 0 IncA protein Bromo_TP PF07524.8 EDN99068.1 - 1.1e-09 37.8 0.1 1.3e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Bromodomain associated L1R_F9L PF02442.12 EDN99068.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses PAS_9 PF13426.1 EDN99071.1 - 2.7e-14 53.4 0.1 8.8e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EDN99071.1 - 0.00019 21.4 0.0 0.0022 17.9 0.0 2.4 1 1 0 1 1 1 1 PAS fold HisKA PF00512.20 EDN99071.1 - 0.00031 20.6 0.1 0.014 15.4 0.0 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EDN99071.1 - 0.0079 16.2 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EDN99071.1 - 0.017 14.9 0.2 0.32 10.7 0.1 2.9 2 1 0 2 2 2 0 PAS fold TFIIH_BTF_p62_N PF08567.6 EDN99073.1 - 0.04 13.5 0.3 0.087 12.4 0.2 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain DUF605 PF04652.11 EDN99073.1 - 6.3 6.0 6.9 8 5.7 4.8 1.1 1 0 0 1 1 1 0 Vta1 like DZR PF12773.2 EDN99074.1 - 0.054 13.3 0.1 0.082 12.7 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Tuberculin PF12198.3 EDN99074.1 - 1.8 8.5 5.1 28 4.7 0.1 2.8 2 0 0 2 2 2 0 Theoretical tuberculin protein CFEM PF05730.6 EDN99075.1 - 4.8e-20 71.1 29.3 1.6e-12 47.0 8.5 2.5 2 0 0 2 2 2 2 CFEM domain IBR PF01485.16 EDN99076.1 - 9.1e-12 44.6 30.2 1e-07 31.7 5.6 2.5 2 0 0 2 2 2 2 IBR domain eIF-3_zeta PF05091.7 EDN99078.1 - 2.8e-207 689.4 0.0 3.3e-207 689.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EDN99078.1 - 0.0071 15.7 0.1 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF569) adh_short PF00106.20 EDN99079.1 - 2e-24 86.3 0.0 3e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN99079.1 - 2.3e-09 37.1 0.0 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN99079.1 - 2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN99079.1 - 0.02 14.6 0.5 0.039 13.7 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EDN99079.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Prenylcys_lyase PF07156.9 EDN99080.1 - 1.9e-09 36.8 0.0 2.8e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EDN99080.1 - 0.0011 18.9 0.3 0.0025 17.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN99080.1 - 0.0068 15.5 0.3 2.4 7.1 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EDN99080.1 - 0.042 13.9 1.9 1 9.3 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN99080.1 - 0.11 12.4 1.2 0.65 9.8 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EDN99081.1 - 8.3e-12 44.4 37.2 1.1e-10 40.8 25.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_11 PF08241.7 EDN99084.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN99084.1 - 3.5e-11 43.0 0.0 4.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN99084.1 - 2e-10 40.9 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN99084.1 - 8.7e-10 39.1 0.0 1.3e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN99084.1 - 1.8e-09 37.3 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN99084.1 - 5.4e-08 33.1 0.0 8.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN99084.1 - 4.1e-06 26.0 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDN99084.1 - 0.0007 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EDN99084.1 - 0.0024 16.8 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EDN99084.1 - 0.0025 16.9 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EDN99084.1 - 0.0055 16.3 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN99084.1 - 0.022 14.8 0.0 0.041 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EDN99084.1 - 0.094 12.0 0.3 0.94 8.8 0.2 2.0 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW EF-hand_7 PF13499.1 EDN99085.1 - 1.9e-13 50.3 0.7 4.5e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDN99085.1 - 1.1e-10 40.4 0.4 0.0012 18.5 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EDN99085.1 - 3.8e-08 33.1 0.0 0.0069 16.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EDN99085.1 - 9.1e-08 30.8 0.5 0.11 11.8 0.0 4.1 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EDN99085.1 - 4.9e-07 29.2 0.1 0.00038 20.0 0.0 3.0 3 1 1 4 4 4 2 EF-hand domain pair UPF0154 PF03672.8 EDN99085.1 - 0.02 14.4 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 EDN99085.1 - 0.061 13.1 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Peptidase_M3 PF01432.15 EDN99087.1 - 5.4e-153 510.3 0.0 7.3e-153 509.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EDN99087.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein DUF2735 PF10931.3 EDN99088.1 - 0.082 13.1 0.1 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) HD_3 PF13023.1 EDN99092.1 - 6.2e-46 156.1 0.0 9.6e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EDN99092.1 - 0.0094 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme MIP-T3 PF10243.4 EDN99093.1 - 2.8 6.3 9.4 4 5.7 6.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDE_1 PF03184.14 EDN99094.1 - 0.00013 21.2 0.3 0.00016 20.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SspH PF08141.7 EDN99094.1 - 0.053 13.5 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein H family RVT_1 PF00078.22 EDN99096.1 - 1.6e-35 122.3 0.6 3.5e-35 121.3 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN99096.1 - 2.5e-21 75.4 3.1 2.9e-21 75.3 1.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN99096.1 - 1.5e-14 54.4 0.0 3.6e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN99096.1 - 8.8e-06 25.8 0.2 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EDN99096.1 - 0.0092 16.2 0.1 0.047 14.0 0.0 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.17 EDN99097.1 - 3.4e-58 197.2 0.0 4.1e-56 190.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MIP-T3 PF10243.4 EDN99098.1 - 7.6 4.8 22.5 10 4.4 15.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sld5 PF05916.6 EDN99099.1 - 1.3e-27 96.2 0.0 1.8e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.11 EDN99100.1 - 2.3e-36 125.2 24.4 8.3e-35 120.1 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EDN99100.1 - 5.4 6.4 18.0 0.024 14.1 2.3 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 EDN99101.1 - 6e-95 318.0 0.0 7.1e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN99101.1 - 5.6e-11 43.2 0.0 1.3e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 EDN99104.1 - 4.1e-17 62.1 0.0 5.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1761 PF08570.5 EDN99107.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF4658 PF15555.1 EDN99108.1 - 0.063 13.1 0.4 0.063 13.1 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) DIE2_ALG10 PF04922.7 EDN99111.1 - 3.2e-35 121.8 0.5 4.8e-35 121.3 0.4 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Polysacc_synt_3 PF13440.1 EDN99111.1 - 0.16 11.4 2.0 0.32 10.4 1.4 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EamA PF00892.15 EDN99111.1 - 0.24 11.4 2.8 0.87 9.6 0.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family PAP1 PF08601.5 EDN99113.1 - 0.085 12.5 27.2 0.1 12.2 18.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 QCR10 PF09796.4 EDN99115.1 - 1.1e-27 95.4 0.1 1.6e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TPR_11 PF13414.1 EDN99116.1 - 1e-18 66.7 3.7 5.4e-15 54.7 0.2 2.3 1 1 1 2 2 2 2 TPR repeat U-box PF04564.10 EDN99116.1 - 3.5e-17 62.1 0.0 6.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.12 EDN99116.1 - 1.3e-11 43.5 5.8 4.7e-06 26.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN99116.1 - 1.9e-11 43.0 6.9 1.9e-06 27.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN99116.1 - 4.2e-09 36.8 0.5 8.7e-07 29.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN99116.1 - 3.5e-08 33.2 1.6 5.8e-05 22.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN99116.1 - 4.3e-08 32.3 1.2 0.034 13.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN99116.1 - 8e-08 32.3 0.8 2.5e-07 30.7 0.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDN99116.1 - 4.8e-07 29.8 0.2 0.0037 17.7 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN99116.1 - 7.3e-06 26.2 0.4 0.00031 21.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDN99116.1 - 0.00033 20.4 0.8 1.2 9.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN99116.1 - 0.00056 19.5 1.5 0.051 13.4 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 EDN99116.1 - 0.00058 19.7 1.4 1.7 8.4 0.1 2.9 2 1 0 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 EDN99116.1 - 0.0053 16.8 3.0 0.071 13.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EDN99116.1 - 0.01 15.2 0.4 0.043 13.1 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 MIT PF04212.13 EDN99116.1 - 0.053 13.4 1.2 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain zf-Nse PF11789.3 EDN99116.1 - 0.14 11.7 0.0 0.68 9.5 0.0 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 EDN99118.1 - 8.4e-31 107.0 0.0 5.1e-27 94.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99118.1 - 8.1e-16 57.8 0.0 1.1e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN99118.1 - 0.0046 15.9 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like DUF572 PF04502.8 EDN99118.1 - 0.66 9.1 4.7 1.1 8.3 3.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDE_1 PF03184.14 EDN99119.1 - 6.9e-05 22.0 0.0 0.00015 21.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3404 PF11884.3 EDN99119.1 - 0.13 11.0 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) F-box PF00646.28 EDN99121.1 - 9.1e-06 25.1 0.5 2.2e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN99121.1 - 6.1e-05 22.6 1.5 0.00012 21.7 1.1 1.5 1 0 0 1 1 1 1 F-box-like COesterase PF00135.23 EDN99122.1 - 2.2e-87 294.0 0.2 2.6e-87 293.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN99122.1 - 4.6e-06 26.3 0.1 3.9e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN99122.1 - 0.0082 15.3 0.4 0.013 14.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_8 PF01501.15 EDN99124.1 - 4e-13 49.2 0.0 5.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDN99124.1 - 0.00088 18.6 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative SGL PF08450.7 EDN99127.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF4569 PF15133.1 EDN99127.1 - 0.075 12.4 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4066 PF13278.1 EDN99128.1 - 4e-18 65.2 0.0 6.7e-18 64.5 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EDN99128.1 - 0.00033 20.1 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 DJ-1/PfpI family Shisa PF13908.1 EDN99129.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator BAR_2 PF10455.4 EDN99130.1 - 6.8e-66 222.1 0.4 9.6e-66 221.6 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDN99130.1 - 1e-18 67.7 2.1 1.1e-17 64.2 1.5 2.0 1 1 0 1 1 1 1 BAR domain TFIIA PF03153.8 EDN99130.1 - 0.0042 17.0 6.0 0.0051 16.7 4.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C4H2 PF10146.4 EDN99130.1 - 0.078 12.9 3.3 0.044 13.8 0.5 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2990 PF11693.3 EDN99130.1 - 0.11 12.3 0.0 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) DUF619 PF04768.8 EDN99131.1 - 5.5e-40 136.5 0.0 1.4e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) NAD_binding_2 PF03446.10 EDN99132.1 - 1.6e-30 106.0 0.1 3.2e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDN99132.1 - 6.1e-11 42.5 0.2 2.1e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EDN99132.1 - 1.4e-10 41.3 0.1 2.2e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EDN99132.1 - 8.2e-09 35.6 0.0 6.3e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 EDN99132.1 - 0.0072 16.8 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EDN99132.1 - 0.017 15.1 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EDN99132.1 - 0.11 11.8 0.4 0.49 9.7 0.1 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP_synt_H PF05493.8 EDN99133.1 - 5.4e-25 87.2 1.3 6e-25 87.0 0.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 EDN99133.1 - 0.033 13.9 0.8 0.042 13.6 0.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Bax1-I PF01027.15 EDN99133.1 - 0.036 13.6 2.0 0.039 13.5 1.4 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Pox_A14 PF05767.7 EDN99133.1 - 0.038 13.9 0.6 0.043 13.7 0.4 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 ABC2_membrane_5 PF13346.1 EDN99133.1 - 0.07 12.4 3.3 0.081 12.2 2.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1129 PF06570.6 EDN99133.1 - 0.13 11.5 0.6 0.16 11.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Anoctamin PF04547.7 EDN99133.1 - 0.14 10.7 3.8 0.18 10.3 2.7 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3692 PF12469.3 EDN99133.1 - 0.2 11.9 1.0 0.32 11.2 0.1 1.6 1 1 1 2 2 2 0 CRISPR-associated protein ABC2_membrane_2 PF12679.2 EDN99133.1 - 0.2 10.4 2.6 0.25 10.1 1.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_2 PF13347.1 EDN99133.1 - 0.89 7.8 4.4 0.93 7.8 3.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Arv1 PF04161.8 EDN99134.1 - 2.6e-18 66.7 0.2 3.4e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Arv1-like family MAD PF05557.8 EDN99135.1 - 0.003 15.7 0.1 0.0038 15.4 0.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Salp15 PF12115.3 EDN99137.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation BBP1_N PF15271.1 EDN99137.1 - 0.076 13.3 0.0 0.099 13.0 0.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DDE_1 PF03184.14 EDN99138.1 - 2.3e-09 36.7 0.0 2.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CRA PF06589.6 EDN99139.1 - 0.058 12.7 0.1 0.067 12.5 0.1 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) ECH PF00378.15 EDN99141.1 - 4.5e-50 170.0 0.0 5.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 EDN99141.1 - 0.00047 19.8 0.1 0.00072 19.2 0.1 1.2 1 0 0 1 1 1 1 TQO small subunit DoxD RRM_6 PF14259.1 EDN99143.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN99143.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN99143.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Macoilin PF09726.4 EDN99146.1 - 9.9 4.3 24.2 18 3.4 16.8 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4136 PF13590.1 EDN99147.1 - 2.6 8.0 7.1 1.4 8.9 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) GalP_UDP_transf PF01087.17 EDN99148.1 - 1.6e-70 236.9 0.0 3.4e-69 232.5 0.0 2.3 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EDN99148.1 - 3.2e-55 186.1 0.0 6.1e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EDN99148.1 - 0.057 13.9 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 HIT domain Kelch_5 PF13854.1 EDN99149.1 - 7.2e-13 48.1 1.1 7.2e-13 48.1 0.8 4.0 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.5 EDN99149.1 - 0.43 9.9 3.7 1 8.6 2.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EDN99149.1 - 0.48 9.9 1.2 1.1 8.8 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HEXIM PF15313.1 EDN99150.1 - 0.42 10.8 6.2 0.065 13.4 1.0 2.1 2 1 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Erg28 PF03694.8 EDN99151.1 - 2.3e-38 130.6 1.7 3e-38 130.2 1.1 1.2 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 EDN99152.1 - 1.1e-20 74.1 0.0 2.5e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99152.1 - 4.3e-09 36.4 0.0 6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99152.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN99152.1 - 0.0014 17.5 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN99152.1 - 0.0023 17.9 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF3798 PF12683.2 EDN99152.1 - 0.054 12.5 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) 3HCDH_N PF02737.13 EDN99152.1 - 0.11 12.1 0.6 0.15 11.6 0.1 1.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDN99152.1 - 0.12 12.4 0.1 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nucleoporin_C PF03177.9 EDN99153.1 - 2.2e-135 452.5 3.9 2.6e-135 452.2 2.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDN99153.1 - 6.9e-91 305.0 0.0 8.9e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like DUF928 PF06051.7 EDN99153.1 - 0.041 13.4 0.1 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) RNase_H PF00075.19 EDN99154.1 - 7.9e-11 42.4 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RNase H DGF-1_4 PF11024.3 EDN99156.1 - 0.019 15.3 3.3 0.022 15.1 2.3 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 FAD_binding_4 PF01565.18 EDN99158.1 - 1.6e-17 63.2 1.7 3.3e-17 62.2 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN99158.1 - 3.3e-06 26.8 0.0 7.8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Rhodanese PF00581.15 EDN99159.1 - 1.1e-12 48.3 0.2 7.5e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain UQ_con PF00179.21 EDN99160.1 - 2.6e-14 52.8 0.0 4.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN99160.1 - 0.00016 21.5 0.4 0.0009 19.1 0.0 2.1 2 0 0 2 2 2 1 RWD domain Mannitol_dh_C PF08125.8 EDN99162.1 - 5e-49 166.6 0.1 6.7e-49 166.2 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EDN99162.1 - 1.7e-19 70.2 0.7 4.4e-19 68.9 0.0 2.0 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EDN99162.1 - 0.0042 16.7 1.3 0.019 14.5 0.0 2.4 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Coatomer_WDAD PF04053.9 EDN99163.1 - 1.8e-170 567.5 0.0 4.8e-170 566.1 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EDN99163.1 - 4.7e-45 149.9 4.3 2e-10 40.1 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EDN99163.1 - 0.00055 18.1 3.6 0.021 12.9 0.1 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EDN99163.1 - 0.0018 18.0 0.0 2.8 7.7 0.0 3.4 2 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DHO_dh PF01180.16 EDN99164.1 - 7.5e-67 225.3 0.1 9.9e-54 182.2 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EDN99164.1 - 0.00048 19.4 3.1 0.1 11.7 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EDN99164.1 - 0.04 12.7 0.0 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lipase_GDSL_2 PF13472.1 EDN99164.1 - 0.061 13.4 0.0 0.24 11.5 0.0 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family gag-asp_proteas PF13975.1 EDN99165.1 - 4.4e-15 55.2 0.1 9.1e-15 54.2 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN99165.1 - 2.4e-10 40.7 0.0 5.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDN99165.1 - 2.1e-09 37.3 1.3 1.2e-08 34.9 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDN99165.1 - 1.6e-06 27.7 2.6 2.8e-06 26.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 EDN99165.1 - 2.3e-05 23.8 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EDN99165.1 - 7.9e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDN99165.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_5 PF14787.1 EDN99165.1 - 0.085 12.3 9.4 0.022 14.2 4.1 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3443 PF11925.3 EDN99165.1 - 0.3 9.7 0.0 0.44 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Pkinase PF00069.20 EDN99166.1 - 2.8e-45 154.4 0.0 5.5e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HR1 PF02185.11 EDN99166.1 - 3.8e-27 93.8 18.3 1.7e-14 53.2 3.0 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_Tyr PF07714.12 EDN99166.1 - 2.6e-25 89.0 0.0 4.4e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EDN99166.1 - 7.1e-19 67.2 36.2 3.1e-11 42.8 6.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Acyl-CoA_dh_1 PF00441.19 EDN99167.1 - 5e-42 143.5 5.9 8e-42 142.8 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN99167.1 - 4.2e-28 98.1 0.6 1.7e-26 93.0 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EDN99167.1 - 1.1e-16 60.0 0.1 2.1e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EDN99167.1 - 1.9e-16 60.5 2.3 3.1e-16 59.8 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 EDN99168.1 - 3.4e-26 91.8 44.1 5.9e-17 61.4 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN99168.1 - 1.4e-06 27.0 23.8 0.0022 16.4 7.2 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EDN99168.1 - 0.00031 19.4 37.4 0.059 11.9 11.6 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1049 PF06305.6 EDN99168.1 - 0.77 9.2 6.1 0.7 9.4 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) eIF-1a PF01176.14 EDN99169.1 - 9e-20 69.8 0.0 1.5e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EDN99170.1 - 9.9e-32 110.5 0.3 1.1e-31 110.3 0.2 1.0 1 0 0 1 1 1 1 ALG3 protein SNF2_N PF00176.18 EDN99171.1 - 1.9e-50 171.3 0.1 3.7e-47 160.5 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN99171.1 - 2.1e-08 33.9 0.0 4.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_cc PF11790.3 EDN99172.1 - 2.7e-69 233.2 0.3 3.2e-69 232.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.8 EDN99172.1 - 0.0037 16.4 0.3 0.0076 15.4 0.2 1.4 1 0 0 1 1 1 1 Fip1 motif Amidase PF01425.16 EDN99173.1 - 2e-106 356.4 0.0 2.4e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 Amidase PQ-loop PF04193.9 EDN99174.1 - 1.1e-10 40.8 4.0 1.1e-10 40.8 2.7 2.5 2 1 1 3 3 3 1 PQ loop repeat TMEM107 PF14995.1 EDN99174.1 - 0.011 15.8 2.7 0.013 15.6 0.6 1.8 1 1 1 2 2 2 0 Transmembrane protein DUF4153 PF13687.1 EDN99174.1 - 0.043 13.3 8.3 0.078 12.4 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) DUF4231 PF14015.1 EDN99174.1 - 0.59 10.1 8.9 1.1 9.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF1049 PF06305.6 EDN99174.1 - 3 7.3 6.3 5.4 6.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF417 PF04224.7 EDN99174.1 - 3.2 7.1 6.5 18 4.6 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF417 Isochorismatase PF00857.15 EDN99175.1 - 5.2e-41 140.4 0.0 6.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DEAD PF00270.24 EDN99179.1 - 3.3e-39 134.0 0.0 5.4e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN99179.1 - 5.8e-19 67.7 0.0 1.4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDN99179.1 - 1.3e-16 59.8 0.0 2.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDN99179.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pantoate_ligase PF02569.10 EDN99180.1 - 4.9e-48 163.2 0.0 4.2e-47 160.2 0.0 2.1 1 1 1 2 2 2 1 Pantoate-beta-alanine ligase PglZ PF08665.7 EDN99181.1 - 0.0075 15.9 0.8 1.8 8.1 0.0 2.2 1 1 0 2 2 2 2 PglZ domain CENP-L PF13092.1 EDN99182.1 - 1.5e-48 164.6 0.0 2.3e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Whi5 PF08528.6 EDN99183.1 - 2e-11 43.1 0.0 3.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Whi5 like Ribonuc_L-PSP PF01042.16 EDN99186.1 - 1.1e-19 70.3 0.0 1.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4177 PF13783.1 EDN99186.1 - 0.077 12.6 0.5 0.13 11.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4177) Zn_clus PF00172.13 EDN99187.1 - 5.4e-05 23.0 10.7 0.00011 22.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_2 PF13091.1 EDN99189.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain XAP5 PF04921.9 EDN99191.1 - 1.4e-80 270.3 0.1 2.7e-80 269.3 0.0 1.5 2 0 0 2 2 2 1 XAP5, circadian clock regulator TPR_11 PF13414.1 EDN99192.1 - 2e-10 40.1 2.0 4.7e-10 38.9 1.4 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EDN99192.1 - 0.00017 21.4 1.3 0.00017 21.4 0.9 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN99192.1 - 0.00023 20.6 1.2 0.39 10.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN99192.1 - 0.00043 19.9 1.2 1.3 9.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN99192.1 - 0.0063 16.6 3.5 0.012 15.6 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDN99192.1 - 0.024 15.2 0.2 2.5 8.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.9 EDN99192.1 - 0.75 7.7 11.3 0.89 7.5 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Cytochrome-c551 PF10643.4 EDN99192.1 - 1.7 7.9 5.3 0.78 8.9 1.7 1.7 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Ycf1 PF05758.7 EDN99192.1 - 4.5 4.8 6.0 4.9 4.7 4.1 1.1 1 0 0 1 1 1 0 Ycf1 RNA_pol_3_Rpc31 PF11705.3 EDN99192.1 - 9.5 6.0 17.9 5.4 6.8 11.0 1.7 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HAD_2 PF13419.1 EDN99193.1 - 1.7e-08 34.8 0.0 7.2e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN99193.1 - 7.2e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN99193.1 - 0.0066 16.8 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1993 PF09351.5 EDN99194.1 - 0.067 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Fip1 PF05182.8 EDN99197.1 - 2.7e-21 74.5 1.3 5.5e-21 73.5 0.9 1.5 1 0 0 1 1 1 1 Fip1 motif BASP1 PF05466.7 EDN99197.1 - 0.44 10.3 19.5 0.67 9.7 13.5 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Nucleoporin_FG PF13634.1 EDN99198.1 - 2.5e-29 101.7 105.7 4.8e-11 42.8 28.6 3.9 2 1 2 4 4 4 3 Nucleoporin FG repeat region SlyX PF04102.7 EDN99198.1 - 0.02 15.2 4.4 0.8 10.1 0.0 3.5 2 2 1 3 3 3 0 SlyX DUF883 PF05957.8 EDN99198.1 - 0.48 10.8 4.5 0.22 11.9 0.4 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin PF00804.20 EDN99198.1 - 2 8.6 5.0 6.2 7.0 1.6 2.6 1 1 1 2 2 2 0 Syntaxin DUF4404 PF14357.1 EDN99198.1 - 3.1 8.2 7.0 1 9.8 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TauD PF02668.11 EDN99199.1 - 5.3e-47 160.6 0.2 6.8e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 EDN99202.1 - 5.6e-07 29.2 8.2 0.29 11.0 0.0 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Fungal_lectin PF07938.7 EDN99205.1 - 0.034 13.4 0.2 1.7 7.8 0.0 2.7 2 1 0 2 2 2 0 Fungal fucose-specific lectin DUF2860 PF11059.3 EDN99206.1 - 0.069 12.1 1.2 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2860) NUC153 PF08159.7 EDN99208.1 - 6.7e-13 47.9 0.2 1.1e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 NUC153 domain LcrG PF07216.7 EDN99208.1 - 2.3 8.2 8.6 0.085 12.8 0.5 2.5 2 2 0 2 2 2 0 LcrG protein NOA36 PF06524.7 EDN99209.1 - 0.026 13.7 5.5 0.034 13.3 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.3 EDN99209.1 - 0.11 12.7 6.4 0.17 12.1 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) Glyco_hydro_3_C PF01915.17 EDN99210.1 - 1.2e-45 155.7 0.0 1.9e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EDN99210.1 - 1.9e-44 151.8 0.0 2.6e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EDN99210.1 - 9.4e-23 79.9 0.1 1.7e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.6 EDN99212.1 - 4.7e-22 78.6 0.0 1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec7 PF01369.15 EDN99213.1 - 2.1e-64 216.6 2.1 2.1e-64 216.6 1.5 2.7 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EDN99213.1 - 1.2e-51 174.4 2.8 1.2e-51 174.4 1.9 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDN99213.1 - 5.5e-32 109.1 1.4 1.3e-30 104.7 0.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Cnd1 PF12717.2 EDN99213.1 - 0.013 15.4 2.7 0.73 9.6 0.1 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 2-oxoacid_dh PF00198.18 EDN99214.1 - 4.3e-77 258.4 0.0 5.7e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDN99214.1 - 9.8e-18 63.5 1.1 1.7e-17 62.7 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDN99214.1 - 5e-07 29.2 1.0 1.3e-06 27.9 0.7 1.8 1 0 0 1 1 1 1 e3 binding domain FYVE PF01363.16 EDN99215.1 - 8.5e-23 80.0 25.8 2.2e-16 59.5 6.1 2.6 2 0 0 2 2 2 2 FYVE zinc finger zf-AN1 PF01428.11 EDN99215.1 - 0.00025 20.8 2.3 0.00025 20.8 1.6 3.6 4 1 0 4 4 4 2 AN1-like Zinc finger Rbsn PF11464.3 EDN99215.1 - 0.0042 16.6 0.1 0.014 14.9 0.1 1.9 1 0 0 1 1 1 1 Rabenosyn Rab binding domain DUF3490 PF11995.3 EDN99215.1 - 0.076 12.5 1.8 0.27 10.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) zf-met PF12874.2 EDN99215.1 - 1.9 8.7 13.2 0.23 11.7 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC5 PF06221.8 EDN99215.1 - 5.2 6.9 17.8 1.5 8.6 0.8 3.9 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type NAD_binding_7 PF13241.1 EDN99216.1 - 2.1e-33 114.6 0.0 3.2e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EDN99216.1 - 6.6e-27 92.6 0.0 1.1e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EDN99216.1 - 8.9e-15 53.3 0.2 1.6e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EDN99216.1 - 0.0073 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDN99216.1 - 0.058 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EDN99216.1 - 0.099 12.4 0.9 0.25 11.1 0.0 2.0 1 1 1 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 EDN99216.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GST_N_3 PF13417.1 EDN99217.1 - 2.1e-10 40.6 0.0 3.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN99217.1 - 2.2e-08 33.9 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN99217.1 - 5e-08 33.3 0.0 8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDN99217.1 - 4.6e-07 29.7 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN99217.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN99217.1 - 6.6e-05 23.0 0.0 0.00022 21.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HTH_psq PF05225.11 EDN99218.1 - 2.1e-09 36.8 0.1 3.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDN99218.1 - 1.9e-07 30.4 0.0 5.3e-07 29.0 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDN99218.1 - 0.017 14.9 0.3 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 NUMOD1 domain HTH_3 PF01381.17 EDN99218.1 - 0.038 13.8 0.2 0.081 12.7 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.1 EDN99218.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 EDN99218.1 - 0.13 11.6 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Zn_clus PF00172.13 EDN99219.1 - 1.2e-08 34.6 10.4 2.3e-08 33.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN99219.1 - 2.5e-07 29.8 0.0 3.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EDN99220.1 - 5.7e-18 65.0 0.0 1.2e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDN99220.1 - 6.4e-09 35.7 0.7 1.7e-08 34.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN99220.1 - 5.3e-07 29.7 0.0 6.6e-05 22.8 1.2 2.6 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN99220.1 - 1.9e-06 27.0 5.5 2.8e-06 26.5 2.9 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EDN99220.1 - 5.8e-05 22.3 0.6 0.00042 19.5 0.3 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EDN99220.1 - 6.9e-05 21.8 4.3 0.0002 20.3 2.3 1.9 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EDN99220.1 - 0.00012 21.1 0.1 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EDN99220.1 - 0.00013 22.3 0.3 0.00032 21.0 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN99220.1 - 0.00013 21.1 0.1 0.00017 20.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN99220.1 - 0.002 16.6 1.5 0.003 16.0 1.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EDN99220.1 - 0.0022 16.8 1.5 0.0033 16.3 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EDN99220.1 - 0.044 13.5 0.5 0.072 12.8 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EDN99220.1 - 0.086 12.8 1.0 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN99220.1 - 0.09 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EDN99220.1 - 0.1 12.2 1.2 0.21 11.2 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EDN99220.1 - 0.11 11.3 0.0 0.4 9.4 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EDN99220.1 - 0.12 11.9 0.3 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 EDN99221.1 - 1.6e-07 31.1 0.0 3e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EDN99221.1 - 3.9e-05 22.8 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EDN99221.1 - 0.00054 19.9 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN99221.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN99221.1 - 0.0056 16.2 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EDN99221.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 EDN99221.1 - 0.058 12.8 0.2 0.15 11.4 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EDN99221.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DDE_1 PF03184.14 EDN99223.1 - 5.1e-11 42.1 0.0 5.3e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN99224.1 - 0.0047 16.8 7.3 0.0076 16.1 5.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Herpes_BLRF2 PF05812.7 EDN99224.1 - 0.14 11.9 3.7 0.64 9.8 2.6 1.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 EDN99224.1 - 0.15 12.3 2.1 0.19 12.0 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3678 PF12435.3 EDN99225.1 - 0.026 14.0 0.3 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) GcpE PF04551.9 EDN99228.1 - 0.08 11.7 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 GcpE protein TALPID3 PF15324.1 EDN99228.1 - 0.72 7.1 10.7 1 6.5 7.4 1.2 1 0 0 1 1 1 0 Hedgehog signalling target PLRV_ORF5 PF01690.12 EDN99228.1 - 6.5 5.7 19.6 11 5.0 13.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDE_1 PF03184.14 EDN99229.1 - 5.2e-31 107.4 0.2 1.3e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN99229.1 - 1.6e-14 53.4 0.0 4.8e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN99229.1 - 0.0001 22.0 0.0 0.0002 21.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3373 PF11853.3 EDN99230.1 - 0.017 13.6 0.5 0.017 13.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3450 PF11932.3 EDN99230.1 - 0.017 14.3 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Clr2 PF10383.4 EDN99232.1 - 2.1e-28 99.0 0.0 3.8e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.18 EDN99233.1 - 5e-29 101.0 0.0 2.9e-21 75.5 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain HDA2-3 PF11496.3 EDN99233.1 - 1.1e-10 40.8 0.2 1.1e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EDN99233.1 - 0.00028 20.6 0.0 0.00078 19.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain C1_1 PF00130.17 EDN99233.1 - 0.00032 20.3 2.3 0.00032 20.3 1.6 2.4 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EDN99233.1 - 0.0019 17.8 11.5 0.0019 17.8 8.0 2.5 1 1 1 2 2 2 1 PHD-finger Vps16_C PF04840.7 EDN99233.1 - 0.0065 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region FYVE PF01363.16 EDN99233.1 - 0.023 14.5 14.7 0.94 9.4 0.2 2.7 2 0 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.11 EDN99235.1 - 1.5e-49 168.6 16.5 1.5e-49 168.6 11.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN99235.1 - 1.4e-08 33.7 7.3 1.4e-08 33.7 5.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDN99235.1 - 0.00055 18.2 5.8 0.00083 17.6 4.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDN99235.1 - 0.0054 14.8 5.8 0.012 13.7 2.1 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF791 PF05631.9 EDN99235.1 - 0.097 11.3 4.1 0.04 12.5 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF791) SNARE PF05739.14 EDN99236.1 - 0.00019 21.0 3.0 0.00019 21.0 2.1 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin-18_N PF10496.4 EDN99236.1 - 0.0028 17.4 1.3 0.009 15.8 0.0 2.4 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus LXG PF04740.7 EDN99236.1 - 0.0061 16.3 1.6 0.0061 16.3 1.1 2.5 3 0 0 3 3 3 1 LXG domain of WXG superfamily DUF2433 PF10360.4 EDN99236.1 - 0.074 13.3 0.7 0.21 11.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) DUF2363 PF10155.4 EDN99236.1 - 0.16 11.8 1.7 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) Aminotran_1_2 PF00155.16 EDN99237.1 - 2e-79 267.2 0.0 2.2e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BHD_3 PF10405.4 EDN99238.1 - 6.7e-27 93.0 0.1 1.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDN99238.1 - 9.7e-18 63.4 0.2 6.7e-17 60.7 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDN99238.1 - 5.4e-13 49.0 0.2 5.4e-13 49.0 0.1 4.6 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDN99238.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily Acid_PPase PF12689.2 EDN99239.1 - 1.1e-67 226.8 0.0 1.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EDN99239.1 - 0.0057 16.8 0.7 0.066 13.4 0.0 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Acetyltransf_10 PF13673.1 EDN99240.1 - 1.7e-06 28.0 0.0 3.7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN99240.1 - 3e-06 27.1 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN99240.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EDN99240.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN99240.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EDN99242.1 - 1.3e-40 139.2 54.6 7.4e-27 93.9 23.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN99242.1 - 3.4e-12 45.4 50.4 9.7e-11 40.6 19.9 2.1 1 1 1 2 2 2 2 Amino acid permease adh_short PF00106.20 EDN99243.1 - 5.8e-10 39.3 0.0 1.9e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99243.1 - 0.00029 20.6 0.0 0.00092 19.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99243.1 - 0.0033 17.1 0.0 0.01 15.5 0.0 1.9 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EDN99243.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding DIOX_N PF14226.1 EDN99244.1 - 3.5e-24 85.5 0.0 8.5e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN99244.1 - 7.4e-17 61.4 0.1 1.9e-16 60.1 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WbqC PF08889.6 EDN99244.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 WbqC-like protein family SRR1 PF07985.7 EDN99245.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 Na_Ca_ex PF01699.19 EDN99248.1 - 1.1e-40 138.4 33.8 8.8e-21 73.9 8.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0564 PF10595.4 EDN99250.1 - 0.14 11.0 0.1 0.16 10.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Aldedh PF00171.17 EDN99251.1 - 7.9e-127 423.3 0.0 9.4e-127 423.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDN99251.1 - 5.3e-06 25.3 0.0 3.1e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.12 EDN99251.1 - 0.054 13.0 1.5 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 ATP synthase subunit D DUF2229 PF09989.4 EDN99251.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) RRM_6 PF14259.1 EDN99252.1 - 8.6e-08 32.0 0.0 2.8e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN99252.1 - 2.7e-07 30.1 0.1 3.7e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN99252.1 - 0.00012 21.8 0.0 0.0021 17.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1399 PF07173.7 EDN99252.1 - 0.18 12.1 0.2 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1399) AAR2 PF05282.6 EDN99252.1 - 0.44 9.4 9.6 0.021 13.7 2.3 1.8 2 0 0 2 2 2 0 AAR2 protein WW PF00397.21 EDN99253.1 - 0.00022 20.9 2.9 0.12 12.3 0.6 2.8 2 0 0 2 2 2 2 WW domain Tropomyosin PF00261.15 EDN99253.1 - 0.02 13.9 0.3 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin G_glu_transpept PF01019.16 EDN99253.1 - 0.03 12.8 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Chitin_synth_2 PF03142.10 EDN99256.1 - 1.7e-228 759.3 0.0 2.2e-228 758.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EDN99256.1 - 1.3e-61 208.5 0.0 9e-61 205.7 0.0 2.3 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EDN99256.1 - 8.9e-16 58.1 2.2 8.9e-16 58.1 1.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EDN99256.1 - 1.3e-15 56.9 2.0 3e-12 46.1 0.1 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EDN99256.1 - 8.5e-14 51.0 1.9 5e-13 48.6 1.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EDN99256.1 - 3.8e-12 46.5 0.0 1.6e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN99256.1 - 6.6e-05 22.2 0.0 0.00024 20.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN99256.1 - 0.00042 20.0 0.0 0.033 13.8 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EDN99258.1 - 1.3e-242 805.9 4.6 1.6e-242 805.6 3.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EDN99258.1 - 9.8e-157 522.9 0.0 2.5e-151 505.0 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 EDN99258.1 - 6e-23 80.4 0.0 1.5e-14 53.5 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EDN99258.1 - 6.4e-17 61.8 3.1 1.4e-16 60.7 2.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN99258.1 - 3.9e-14 53.0 0.2 1.7e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDN99258.1 - 0.00015 21.4 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDN99258.1 - 0.0048 16.1 0.2 0.046 13.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 21 Peptidase_M20 PF01546.23 EDN99259.1 - 2e-17 63.3 0.0 3.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EDN99259.1 - 1.7e-12 46.6 9.2 0.0013 18.4 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.9 EDN99259.1 - 9.2e-07 28.5 0.0 7.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EDN99259.1 - 0.021 14.5 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M28 Asparaginase_2 PF01112.13 EDN99262.1 - 2.1e-36 125.2 0.2 2.6e-33 115.0 0.0 3.4 2 1 0 2 2 2 2 Asparaginase Cloacin PF03515.9 EDN99263.1 - 0.88 8.7 5.1 0.95 8.6 3.5 1.1 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain RPA_C PF08784.6 EDN99263.1 - 4 7.9 7.9 5 7.5 5.5 1.2 1 0 0 1 1 1 0 Replication protein A C terminal Sugar_tr PF00083.19 EDN99265.1 - 2.5e-65 220.8 23.9 3.6e-51 174.1 3.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN99265.1 - 1.2e-17 63.7 38.4 3.5e-11 42.4 12.1 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EDN99267.1 - 1.1e-17 63.7 3.4 2.1e-17 62.8 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN99267.1 - 3.6e-10 39.5 2.0 4.5e-10 39.2 0.4 2.0 2 0 0 2 2 2 1 Berberine and berberine like Ras PF00071.17 EDN99268.1 - 6.1e-20 71.2 0.0 6.9e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN99268.1 - 8.3e-11 42.4 0.0 1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN99268.1 - 9.1e-05 22.3 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN99268.1 - 0.00094 18.7 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain G-alpha PF00503.15 EDN99268.1 - 0.0044 15.7 0.0 0.0056 15.4 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.1 EDN99268.1 - 0.0069 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EDN99268.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EDN99268.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDN99268.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EDN99268.1 - 0.017 14.3 0.5 0.064 12.4 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN99268.1 - 0.028 14.2 0.1 0.041 13.6 0.1 1.7 1 1 0 1 1 1 0 Dynamin family cobW PF02492.14 EDN99268.1 - 0.032 13.6 0.1 3.9 6.8 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EDN99268.1 - 0.034 13.8 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EDN99268.1 - 0.035 13.1 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Septin TrwB_AAD_bind PF10412.4 EDN99268.1 - 0.036 12.6 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EDN99268.1 - 0.056 12.6 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HTH_26 PF13443.1 EDN99268.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain AIG1 PF04548.11 EDN99268.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AhpC-TSA PF00578.16 EDN99269.1 - 9.2e-35 119.0 0.0 1.7e-34 118.1 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDN99269.1 - 2.1e-15 56.5 0.0 2.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDN99269.1 - 7.7e-13 47.8 0.6 1.3e-12 47.0 0.4 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin COX15-CtaA PF02628.10 EDN99272.1 - 4.2e-95 318.1 8.1 5e-95 317.8 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3325 PF11804.3 EDN99272.1 - 0.013 15.3 2.6 0.013 15.3 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) PQ-loop PF04193.9 EDN99272.1 - 0.063 12.8 2.1 5 6.7 0.1 2.9 2 0 0 2 2 2 0 PQ loop repeat DUF3328 PF11807.3 EDN99274.1 - 2.2e-40 138.6 0.0 2.8e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_18 PF00704.23 EDN99276.1 - 7.6e-38 130.8 2.5 7.6e-38 130.8 1.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EDN99276.1 - 0.0021 17.9 0.2 0.0071 16.2 0.0 2.0 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.14 EDN99276.1 - 0.0051 16.7 6.9 0.0051 16.7 4.8 3.1 3 0 0 3 3 3 1 Chitin recognition protein DUF2850 PF11012.3 EDN99276.1 - 0.076 13.1 0.2 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) LAMTOR PF15454.1 EDN99280.1 - 1.6e-17 63.5 0.1 2.8e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator End3 PF12761.2 EDN99281.1 - 0.11 12.1 1.5 0.14 11.7 1.0 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF724 PF05266.9 EDN99281.1 - 0.23 11.0 2.2 0.27 10.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RPEL PF02755.10 EDN99284.1 - 1.7e-05 23.9 0.0 3.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RPEL repeat F-box PF00646.28 EDN99284.1 - 0.00026 20.5 1.4 0.00044 19.8 1.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN99284.1 - 0.0037 16.9 0.9 0.0063 16.2 0.6 1.3 1 0 0 1 1 1 1 F-box-like Zn_clus PF00172.13 EDN99286.1 - 1.1e-08 34.8 10.9 1.1e-08 34.8 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN99286.1 - 6e-06 25.3 0.6 0.014 14.2 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Ank_2 PF12796.2 EDN99287.1 - 2e-34 117.7 0.1 2.1e-17 63.2 0.3 5.0 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN99287.1 - 5.3e-29 98.5 5.4 1.1e-06 28.1 0.2 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EDN99287.1 - 4.3e-27 93.9 1.1 6.1e-10 39.3 0.0 6.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN99287.1 - 3.2e-23 81.2 0.3 1e-09 38.3 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN99287.1 - 5.7e-21 72.5 5.2 0.002 18.1 0.2 7.8 7 0 0 7 7 7 5 Ankyrin repeat HeLo PF14479.1 EDN99288.1 - 1.5e-37 129.4 1.4 1.9e-37 129.1 0.9 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation ALIX_LYPXL_bnd PF13949.1 EDN99288.1 - 0.051 12.5 0.9 0.076 11.9 0.6 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DLH PF01738.13 EDN99289.1 - 3.3e-12 46.1 0.0 1.1e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDN99289.1 - 0.00014 21.5 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2_jaz PF12171.3 EDN99290.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN99290.1 - 0.005 16.9 0.2 0.0087 16.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN99290.1 - 0.013 15.6 0.2 0.013 15.6 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4646 PF15496.1 EDN99290.1 - 0.013 15.5 0.1 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Fzo_mitofusin PF04799.8 EDN99290.1 - 0.45 9.8 2.4 0.73 9.1 1.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region V_ATPase_I PF01496.14 EDN99290.1 - 0.58 7.9 7.3 0.87 7.3 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPX PF03105.14 EDN99290.1 - 2 8.1 16.6 1.2 8.8 7.7 2.1 2 0 0 2 2 2 0 SPX domain IncA PF04156.9 EDN99290.1 - 3.3 7.2 10.7 1.9 8.0 6.1 1.5 2 0 0 2 2 2 0 IncA protein Cwf_Cwc_15 PF04889.7 EDN99290.1 - 4.4 6.9 26.2 10 5.7 13.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SPOC PF07744.8 EDN99291.1 - 1.8e-18 67.1 0.0 4.6e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EDN99291.1 - 2e-16 60.0 1.1 6.1e-16 58.5 0.7 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EDN99291.1 - 8.5e-09 34.9 7.5 1.7e-08 34.0 5.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN99291.1 - 0.0098 15.1 4.9 0.018 14.3 3.4 1.4 1 0 0 1 1 1 1 PHD-finger DDE_1 PF03184.14 EDN99292.1 - 0.02 14.0 0.1 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Bac_thur_toxin PF01338.13 EDN99293.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis toxin rve PF00665.21 EDN99295.1 - 1.6e-18 66.9 0.0 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDN99295.1 - 5.5e-06 25.6 0.4 1.1e-05 24.6 0.3 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Ank_2 PF12796.2 EDN99299.1 - 4.5e-10 39.7 0.1 2.1e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN99299.1 - 6.5e-10 38.2 0.4 0.099 12.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EDN99299.1 - 2.8e-08 33.7 0.1 0.088 13.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN99299.1 - 1.2e-07 32.0 0.1 0.011 16.2 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN99299.1 - 3.9e-05 23.2 1.1 0.52 10.2 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeat tRNA-synt_2 PF00152.15 EDN99300.1 - 4.3e-91 305.1 2.4 4.3e-91 305.1 1.6 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN99300.1 - 3.4e-11 42.8 0.1 8.8e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDN99300.1 - 1.1e-06 28.0 0.8 0.0033 16.6 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) MORN PF02493.15 EDN99301.1 - 0.15 11.8 0.6 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 MORN repeat DUF2673 PF10880.3 EDN99303.1 - 0.38 10.8 0.1 0.38 10.8 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2673) p450 PF00067.17 EDN99305.1 - 5.9e-57 193.2 0.0 7.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EDN99308.1 - 1.4e-24 86.8 0.1 6.6e-24 84.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN99308.1 - 5.2e-05 22.2 0.0 0.00013 20.8 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EDN99308.1 - 5.8e-05 23.0 0.1 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN99308.1 - 0.00022 20.2 0.0 0.12 11.2 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EDN99308.1 - 0.00048 19.2 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EDN99308.1 - 0.096 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DnaG_DnaB_bind PF08278.6 EDN99308.1 - 0.15 12.3 2.4 0.66 10.1 0.1 2.7 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Pyridox_oxidase PF01243.15 EDN99309.1 - 1e-09 38.2 0.0 4e-07 29.9 0.0 2.8 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EDN99309.1 - 4e-08 32.7 0.0 1.3e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain FAD_binding_6 PF00970.19 EDN99309.1 - 5.3e-07 29.6 0.0 5.6e-05 23.1 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Abhydrolase_3 PF07859.8 EDN99310.1 - 4.6e-57 192.9 0.0 5.8e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN99310.1 - 1e-06 27.7 0.3 2e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EDN99310.1 - 0.00077 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EDN99310.1 - 0.031 12.9 0.0 0.04 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) ADH_zinc_N PF00107.21 EDN99311.1 - 5.2e-18 64.8 0.5 9.7e-18 63.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN99311.1 - 1.8e-07 30.8 0.8 1.7e-06 27.7 0.1 2.2 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 EDN99311.1 - 0.0019 18.2 0.1 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.1 EDN99311.1 - 0.042 14.2 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.20 EDN99311.1 - 0.056 12.6 0.1 0.074 12.2 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.13 EDN99311.1 - 0.064 13.2 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF747 PF05346.6 EDN99312.1 - 3.4e-133 443.8 4.5 4.3e-133 443.4 3.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_methylase PF00145.12 EDN99313.1 - 3e-11 43.0 0.0 4.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RNA_pol_3_Rpc31 PF11705.3 EDN99313.1 - 0.044 13.7 6.7 0.086 12.7 4.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.7 EDN99313.1 - 1.1 8.4 8.4 1.5 7.9 5.8 1.2 1 0 0 1 1 1 0 SDA1 DNA_methylase PF00145.12 EDN99314.1 - 7.4e-12 45.0 0.6 8.8e-11 41.5 0.0 2.6 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EDN99314.1 - 7e-09 35.4 3.4 7.9e-09 35.2 0.7 2.2 2 0 0 2 2 2 1 BAH domain Methyltransf_15 PF09445.5 EDN99314.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FA_desaturase PF00487.19 EDN99316.1 - 7.1e-36 123.9 23.6 9.1e-36 123.6 16.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EDN99316.1 - 5.4e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tr-sialidase_C PF11052.3 EDN99317.1 - 3 7.7 8.1 8.1 6.4 5.6 1.7 1 0 0 1 1 1 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal MFS_1 PF07690.11 EDN99320.1 - 1e-32 113.2 27.9 1e-32 113.2 19.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MgtC PF02308.11 EDN99320.1 - 0.18 11.6 3.3 0.17 11.6 0.5 2.2 2 0 0 2 2 2 0 MgtC family Pkinase PF00069.20 EDN99321.1 - 1.6e-05 24.1 0.0 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN99321.1 - 0.0054 16.4 0.3 0.0097 15.6 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4264 PF14084.1 EDN99321.1 - 0.0062 15.8 0.0 2.1 7.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4264) Kdo PF06293.9 EDN99321.1 - 0.074 12.0 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.17 EDN99326.1 - 3.1e-06 27.3 0.0 1.8e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EDN99327.1 - 2.7e-22 79.6 0.0 3.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2 PF01569.16 EDN99328.1 - 5.3e-17 61.7 3.1 1.6e-16 60.1 2.1 1.8 1 0 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 EDN99329.1 - 1.6e-48 164.1 0.0 1.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN99329.1 - 1.8e-12 47.8 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN99329.1 - 2.8e-05 23.4 0.0 5e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN99329.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDN99329.1 - 0.041 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.5 EDN99330.1 - 2.2e-24 84.9 0.8 3.9e-24 84.1 0.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 Gly-zipper_YMGG PF13441.1 EDN99333.1 - 0.031 13.8 15.8 0.043 13.3 5.5 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EDN99333.1 - 0.3 10.7 21.9 2 8.1 10.3 2.7 2 1 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EDN99333.1 - 1.7 8.3 26.1 0.87 9.2 2.2 3.1 2 1 1 3 3 3 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EDN99333.1 - 7.7 6.1 12.9 5 6.8 0.6 3.4 2 1 1 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain bZIP_1 PF00170.16 EDN99334.1 - 0.0078 16.1 0.7 0.013 15.4 0.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EDN99334.1 - 0.18 11.6 1.5 1.7 8.4 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein NPV_P10 PF05531.7 EDN99335.1 - 0.001 19.2 2.2 0.001 19.2 1.5 10.8 7 3 2 11 11 11 1 Nucleopolyhedrovirus P10 protein DUF2087 PF09860.4 EDN99335.1 - 0.0065 16.1 7.9 2.3 8.0 0.1 4.8 5 0 0 5 5 5 3 Uncharacterized protein conserved in bacteria (DUF2087) Tht1 PF04163.7 EDN99336.1 - 6.1e-06 24.9 0.6 1.1e-05 24.0 0.3 1.5 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DASH_Duo1 PF08651.5 EDN99336.1 - 0.096 12.2 0.1 0.4 10.2 0.1 2.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 NBP1 PF08537.5 EDN99336.1 - 0.17 11.0 0.3 0.29 10.3 0.2 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Ribosomal_L6 PF00347.18 EDN99337.1 - 6.3e-24 84.2 1.0 2.1e-12 47.3 0.0 3.4 3 1 1 4 4 4 2 Ribosomal protein L6 Inositol_P PF00459.20 EDN99338.1 - 6.4e-51 173.2 3.8 1.1e-50 172.4 2.6 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family HTH_37 PF13744.1 EDN99338.1 - 0.02 14.6 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C3HC PF07967.8 EDN99339.1 - 5.3e-44 149.2 5.2 3e-39 133.8 0.9 2.6 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 EDN99339.1 - 7e-31 105.9 5.5 1.4e-28 98.5 0.3 2.5 2 0 0 2 2 2 2 Rsm1-like BIR PF00653.16 EDN99339.1 - 0.00026 21.3 2.5 0.0011 19.3 0.4 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain FAD_binding_3 PF01494.14 EDN99340.1 - 1e-11 44.5 0.0 3.1e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain tRNA_int_end_N2 PF12928.2 EDN99341.1 - 5.8e-26 89.7 0.1 9.7e-26 89.0 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EDN99341.1 - 0.002 17.6 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Bromodomain PF00439.20 EDN99343.1 - 1.7e-22 79.1 0.0 2.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain Flavodoxin_5 PF12724.2 EDN99343.1 - 0.077 12.9 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 Flavodoxin domain WD40 PF00400.27 EDN99344.1 - 1.8e-20 72.0 13.2 6.5e-07 29.0 0.4 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat IKI3 PF04762.7 EDN99344.1 - 0.0009 17.1 0.0 0.0013 16.6 0.0 1.2 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 EDN99344.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Miro PF08477.8 EDN99345.1 - 3.7e-35 121.0 0.0 3.2e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EDN99345.1 - 2.8e-34 116.7 0.0 5.7e-34 115.7 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EDN99345.1 - 1.3e-31 107.6 0.1 2.3e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EDN99345.1 - 8.8e-25 86.9 0.0 8.1e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EDN99345.1 - 6.7e-08 32.4 0.0 0.00022 21.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EDN99345.1 - 1.1e-06 28.6 0.3 0.052 13.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 EDN99345.1 - 1.3e-06 28.3 0.9 0.17 11.7 0.0 3.7 3 1 1 4 4 3 2 Dynamin family EF-hand_1 PF00036.27 EDN99345.1 - 4.4e-06 25.6 5.5 0.03 13.6 0.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EDN99345.1 - 1.7e-05 24.2 4.2 0.083 12.8 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_29 PF13555.1 EDN99345.1 - 2.7e-05 23.5 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN99345.1 - 4.3e-05 23.5 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDN99345.1 - 0.00054 20.1 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EDN99345.1 - 0.00063 19.2 0.0 0.78 9.1 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EDN99345.1 - 0.0023 17.6 0.0 0.31 10.7 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EDN99345.1 - 0.0044 16.2 0.0 0.53 9.4 0.1 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family EF-hand_5 PF13202.1 EDN99345.1 - 0.0072 15.6 9.5 0.31 10.4 1.8 2.8 2 0 0 2 2 2 2 EF hand RNA_helicase PF00910.17 EDN99345.1 - 0.0083 16.2 0.0 0.22 11.7 0.0 2.8 3 0 0 3 3 2 1 RNA helicase DUF258 PF03193.11 EDN99345.1 - 0.017 14.3 0.0 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDN99345.1 - 0.029 14.6 0.0 5 7.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Septin PF00735.13 EDN99345.1 - 0.033 13.2 0.0 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_21 PF13304.1 EDN99345.1 - 0.049 13.6 1.7 4.7 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EDN99345.1 - 0.099 12.2 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain EF-hand_8 PF13833.1 EDN99345.1 - 0.1 12.2 4.5 2.8 7.6 0.8 2.5 2 0 0 2 2 2 0 EF-hand domain pair FtsK_SpoIIIE PF01580.13 EDN99345.1 - 0.11 11.9 0.1 12 5.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 EDN99345.1 - 0.18 10.6 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RPN7 PF10602.4 EDN99346.1 - 7.2e-56 188.3 0.4 1.2e-55 187.6 0.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDN99346.1 - 8.5e-13 48.5 0.0 1.9e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EDN99346.1 - 0.084 13.5 0.2 0.8 10.5 0.1 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Lin0512_fam PF09585.5 EDN99346.1 - 0.09 12.3 0.3 0.55 9.8 0.1 2.4 2 1 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) TPR_7 PF13176.1 EDN99346.1 - 0.15 11.8 1.2 0.48 10.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat BEX PF04538.7 EDN99346.1 - 0.43 10.8 3.9 0.76 10.0 2.7 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family Pox_MCEL PF03291.11 EDN99347.1 - 6.6e-63 212.5 0.0 2.6e-31 108.7 0.0 3.5 2 1 1 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 EDN99347.1 - 1.3e-08 35.1 0.1 0.0039 17.6 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EDN99347.1 - 8.6e-07 29.3 0.0 0.01 16.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EDN99347.1 - 3e-06 27.7 0.0 8.9e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN99347.1 - 3.1e-06 26.9 0.0 5.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN99347.1 - 3.5e-06 26.6 0.0 0.00042 19.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN99347.1 - 8.6e-05 22.8 0.0 0.00035 20.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDN99347.1 - 0.006 15.5 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.6 EDN99347.1 - 0.098 11.3 0.0 0.22 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Aminotran_1_2 PF00155.16 EDN99348.1 - 3.9e-41 141.2 0.0 5.6e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GDPD PF03009.12 EDN99349.1 - 1.1e-72 244.6 0.0 2.4e-72 243.5 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EDN99349.1 - 4.5e-28 97.4 0.4 1.2e-11 44.7 0.4 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 EDN99349.1 - 4.4e-27 95.5 7.5 3.4e-15 56.5 1.4 4.0 2 1 1 3 3 3 2 SPX domain Ank PF00023.25 EDN99349.1 - 9.4e-25 85.1 3.2 1.3e-06 27.9 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EDN99349.1 - 4.9e-23 81.0 4.7 5.9e-08 33.0 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN99349.1 - 3.4e-19 68.4 2.8 4.8e-06 26.6 0.0 6.3 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN99349.1 - 8.4e-14 50.3 1.4 0.013 15.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat DUF4393 PF14337.1 EDN99349.1 - 0.029 13.7 0.3 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) HTH_psq PF05225.11 EDN99351.1 - 1.1e-13 50.4 0.5 1.5e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN99351.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN99351.1 - 0.017 15.1 0.1 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDN99351.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain HTH_23 PF13384.1 EDN99351.1 - 0.059 13.0 0.1 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain DBR1 PF05011.8 EDN99352.1 - 2.3e-49 166.9 0.1 2.3e-49 166.9 0.0 1.8 2 1 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EDN99352.1 - 3.9e-07 29.6 1.3 7.5e-07 28.7 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Bacillus_PapR PF05968.6 EDN99352.1 - 0.036 14.1 0.5 0.092 12.8 0.4 1.6 1 0 0 1 1 1 0 Bacillus PapR protein FYDLN_acid PF09538.5 EDN99352.1 - 7.2 7.2 11.1 7.2 7.2 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rpr2 PF04032.11 EDN99353.1 - 9.3e-17 60.6 1.3 1.7e-16 59.8 0.9 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 EDN99353.1 - 0.0018 17.9 2.2 0.003 17.2 0.1 2.1 2 0 0 2 2 2 1 Nudix N-terminal DUF3133 PF11331.3 EDN99353.1 - 0.37 10.3 5.0 5.6 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) zf-ZPR1 PF03367.8 EDN99354.1 - 5.7e-105 347.4 0.3 8.5e-53 177.8 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain FMN_red PF03358.10 EDN99355.1 - 3.2e-23 81.9 0.0 5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Abhydrolase_5 PF12695.2 EDN99356.1 - 6.7e-06 25.9 0.0 3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN99356.1 - 0.00022 21.0 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EDN99356.1 - 0.0022 17.9 0.0 0.0086 15.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Phage_Mu_Gp45 PF06890.7 EDN99356.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein AXE1 PF05448.7 EDN99356.1 - 0.062 11.7 0.0 1.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ketoacyl-synt PF00109.21 EDN99357.1 - 1.1e-58 198.7 0.0 2.1e-58 197.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EDN99357.1 - 2.1e-53 180.6 0.1 5.2e-53 179.3 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EDN99357.1 - 2.6e-53 181.0 0.0 4.2e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EDN99357.1 - 2.3e-49 168.4 0.0 3.4e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EDN99357.1 - 8.1e-39 133.2 0.1 2.1e-38 131.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDN99357.1 - 9.3e-31 106.1 0.9 2.5e-30 104.7 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_N PF08240.7 EDN99357.1 - 1.2e-08 34.7 0.1 3.7e-08 33.0 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDN99357.1 - 6.6e-07 30.2 0.0 2.1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN99357.1 - 0.0021 17.6 1.0 0.005 16.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_4 PF01565.18 EDN99358.1 - 1.1e-18 67.0 0.6 2.2e-18 66.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN99358.1 - 5.5e-11 42.1 0.4 1.4e-10 40.9 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EDN99358.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding BTB PF00651.26 EDN99359.1 - 4.8e-10 39.4 0.0 2.7e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain Chromo PF00385.19 EDN99359.1 - 2.4e-09 36.7 0.2 6.9e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 EDN99359.1 - 0.083 12.8 0.1 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF2433 PF10360.4 EDN99362.1 - 1.1e-54 184.2 0.0 2e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EDN99362.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 EDN99362.1 - 0.031 13.6 19.8 0.053 12.9 13.7 1.3 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 EDN99362.1 - 0.17 12.1 10.4 9.3 6.5 7.3 2.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TFIIA PF03153.8 EDN99362.1 - 1.6 8.5 11.3 2.2 8.1 7.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 EDN99362.1 - 3.1 6.1 6.2 4.3 5.6 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 EDN99362.1 - 7.7 4.6 20.1 12 3.9 13.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ubie_methyltran PF01209.13 EDN99363.1 - 2.2e-78 262.5 0.0 2.8e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDN99363.1 - 1.9e-14 53.4 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN99363.1 - 5e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN99363.1 - 7.1e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN99363.1 - 2.6e-08 34.1 0.0 4.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN99363.1 - 1.2e-07 31.6 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN99363.1 - 1.3e-06 28.9 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN99363.1 - 0.00011 22.1 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain E1_dh PF00676.15 EDN99364.1 - 7.3e-74 248.1 0.0 3.7e-64 216.3 0.0 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EDN99364.1 - 0.0019 17.8 0.0 0.0095 15.5 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EDN99364.1 - 0.021 13.7 0.0 0.38 9.6 0.0 2.5 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EDN99364.1 - 0.1 11.1 0.0 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 XFP N-terminal domain Smr PF01713.16 EDN99365.1 - 6.3e-12 45.5 0.4 1.4e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EDN99365.1 - 1.6e-07 31.2 1.5 1.6e-07 31.2 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) FimH_man-bind PF09160.5 EDN99365.1 - 0.048 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 FimH, mannose binding CUE PF02845.11 EDN99365.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 CUE domain Patched PF02460.13 EDN99368.1 - 3.3e-77 260.1 12.7 9.2e-50 169.3 0.3 2.6 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 EDN99368.1 - 4e-52 175.7 7.0 4e-52 175.7 4.8 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EDN99368.1 - 2.7e-06 26.3 24.8 1.2e-05 24.1 5.8 2.5 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.9 EDN99368.1 - 0.00027 20.6 0.8 0.00058 19.5 0.6 1.5 1 0 0 1 1 1 1 Folate receptor family CTP_transf_2 PF01467.21 EDN99369.1 - 3.2e-30 105.2 0.0 3.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HECT PF00632.20 EDN99370.1 - 1.4e-81 274.0 0.0 2.5e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EDN99370.1 - 0.16 12.1 1.0 14 6.1 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat DDE_1 PF03184.14 EDN99371.1 - 4.2e-09 35.8 5.2 1.1e-06 27.9 0.5 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN99371.1 - 7.4e-07 28.8 1.2 1.5e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain COesterase PF00135.23 EDN99372.1 - 3.6e-85 286.6 0.0 4.3e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN99372.1 - 6.7e-07 29.0 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN99372.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EDN99374.1 - 5.7e-36 123.9 31.2 6.8e-36 123.6 21.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EDN99374.1 - 0.042 13.8 10.3 0.12 12.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) APH PF01636.18 EDN99375.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDN99375.1 - 0.0071 15.0 0.0 0.0084 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EDN99375.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EDN99375.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Complex1_30kDa PF00329.14 EDN99376.1 - 6.3e-35 119.5 0.0 1e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EDN99377.1 - 9.3e-20 69.9 12.2 1.5e-19 69.2 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EDN99377.1 - 3.3e-06 26.6 0.0 1.1e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EDN99377.1 - 5.4e-06 25.9 6.5 1.1e-05 25.0 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EDN99377.1 - 8.7e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EDN99377.1 - 0.00068 19.4 8.7 0.0012 18.6 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EDN99377.1 - 0.00086 18.5 3.5 0.00086 18.5 2.4 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger RRM_6 PF14259.1 EDN99377.1 - 0.0053 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EDN99377.1 - 0.04 13.6 6.2 0.09 12.5 4.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SET_assoc PF11767.3 EDN99377.1 - 0.091 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated FYVE PF01363.16 EDN99377.1 - 0.098 12.5 3.0 0.23 11.4 2.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.1 EDN99377.1 - 0.16 11.7 3.4 0.37 10.5 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EDN99377.1 - 0.18 11.4 11.2 0.4 10.3 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN99377.1 - 0.42 10.6 11.1 0.87 9.6 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EDN99377.1 - 3.1 7.4 10.6 2.6 7.6 3.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PNP_UDP_1 PF01048.15 EDN99379.1 - 3.7e-38 130.8 0.2 4.4e-38 130.5 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2694 PF10904.3 EDN99379.1 - 0.028 14.4 0.1 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Med13_C PF06333.7 EDN99380.1 - 1.8e-120 402.3 0.2 1.8e-120 402.3 0.1 2.4 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EDN99380.1 - 1.9e-80 270.5 0.1 1.9e-80 270.5 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EDN99381.1 - 5.8e-14 51.3 1.4 1.5e-13 50.0 1.0 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EDN99381.1 - 2.7e-05 23.8 0.3 0.28 11.1 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat NYD-SP28_assoc PF14775.1 EDN99383.1 - 8.3 6.1 19.2 1.8 8.3 0.6 5.8 5 0 0 5 5 5 0 Sperm tail C-terminal domain PAS_9 PF13426.1 EDN99386.1 - 2.1e-16 60.1 0.0 3.7e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EDN99386.1 - 0.0033 17.1 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EDN99386.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF2434 PF10361.4 EDN99386.1 - 0.033 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Ribosomal_L29e PF01779.12 EDN99386.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L29e protein family DUF4342 PF14242.1 EDN99387.1 - 0.32 10.7 2.1 0.31 10.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Bac_export_2 PF01312.14 EDN99388.1 - 0.083 11.7 1.2 0.082 11.7 0.8 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fzo_mitofusin PF04799.8 EDN99388.1 - 3.4 7.0 5.8 3.9 6.8 4.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region Chromo PF00385.19 EDN99389.1 - 0.0058 16.2 1.4 0.013 15.1 1.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1383 PF07134.6 EDN99390.1 - 0.02 13.8 0.0 0.024 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) RTA1 PF04479.8 EDN99392.1 - 1.8e-38 132.2 12.1 1.5e-34 119.4 4.3 2.1 2 0 0 2 2 2 2 RTA1 like protein DUF4017 PF13209.1 EDN99392.1 - 0.32 10.8 0.0 0.32 10.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4017) zf-DHHC PF01529.15 EDN99392.1 - 8.4 5.7 12.2 4.6e+02 0.0 8.5 2.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Fungal_trans_2 PF11951.3 EDN99393.1 - 3.7e-07 29.0 1.9 5e-06 25.3 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN99393.1 - 0.00019 21.2 4.5 0.00049 19.9 3.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4474 PF14751.1 EDN99393.1 - 0.027 13.6 0.5 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4474) Sporozoite_P67 PF05642.6 EDN99396.1 - 1.9 6.2 17.5 1 7.1 2.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.12 EDN99396.1 - 3.7 7.3 29.7 3.2 7.5 4.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3328 PF11807.3 EDN99397.1 - 2.6e-52 177.6 0.0 3.1e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ion_trans_2 PF07885.11 EDN99399.1 - 2.7e-27 94.3 30.2 7.5e-17 60.8 4.1 3.2 3 0 0 3 3 3 2 Ion channel ABC_tran PF00005.22 EDN99400.1 - 3.4e-14 53.3 0.0 6.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EDN99400.1 - 4.1e-13 48.9 9.2 8.5e-13 47.9 6.4 1.5 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 EDN99400.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bradykinin PF06753.7 EDN99400.1 - 0.11 12.0 0.9 1.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Bradykinin SbcCD_C PF13558.1 EDN99400.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit zf-TRAF PF02176.13 EDN99401.1 - 5.4e-12 45.9 31.0 3.2e-05 24.1 4.2 3.8 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4 PF00097.20 EDN99401.1 - 2.7e-07 30.1 6.0 2.7e-07 30.1 4.1 3.8 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN99401.1 - 4.1e-07 29.9 6.0 4.1e-07 29.9 4.2 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDN99401.1 - 8.4e-07 28.7 6.9 8.4e-07 28.7 4.8 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDN99401.1 - 2.9e-06 26.9 5.9 2.9e-06 26.9 4.1 3.5 2 1 2 4 4 2 1 Ring finger domain zf-RING_5 PF14634.1 EDN99401.1 - 1.7e-05 24.4 3.6 1.7e-05 24.4 2.5 3.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN99401.1 - 2.5e-05 23.8 4.1 2.5e-05 23.8 2.8 3.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDN99401.1 - 0.00014 21.2 4.9 0.00051 19.5 3.4 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN99401.1 - 0.00021 20.9 5.0 0.00021 20.9 3.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EDN99401.1 - 0.0013 18.7 3.2 0.0013 18.7 2.2 3.8 2 2 1 3 3 2 1 RING-H2 zinc finger zf-TFIIB PF13453.1 EDN99401.1 - 0.02 14.0 15.7 0.27 10.4 3.8 3.7 3 1 0 3 3 3 0 Transcription factor zinc-finger zf-P11 PF03854.9 EDN99401.1 - 0.023 14.1 0.5 0.023 14.1 0.3 3.4 2 1 1 3 3 3 0 P-11 zinc finger zf-RING_3 PF14369.1 EDN99401.1 - 3 7.9 13.8 34 4.5 0.2 4.8 4 0 0 4 4 4 0 zinc-finger IATP PF04568.7 EDN99401.1 - 5.2 7.1 5.7 2.4 8.2 0.3 2.7 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-RING_6 PF14835.1 EDN99401.1 - 8.4 6.2 11.0 0.1 12.3 1.2 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein SNARE PF05739.14 EDN99402.1 - 6.6e-15 54.5 4.4 1.3e-14 53.6 3.1 1.5 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.13 EDN99402.1 - 0.0086 14.1 0.2 0.012 13.6 0.2 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 Use1 PF09753.4 EDN99402.1 - 0.067 12.6 1.4 0.11 11.9 1.0 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 ODV-E18 PF10717.4 EDN99402.1 - 0.1 12.0 1.6 0.21 11.0 1.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 EDN99402.1 - 0.11 12.5 0.3 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HOOK PF05622.7 EDN99402.1 - 0.51 8.0 8.3 0.13 9.9 1.4 2.0 2 0 0 2 2 2 0 HOOK protein Synaptobrevin PF00957.16 EDN99402.1 - 6 6.5 11.0 1.2 8.7 4.9 2.0 2 1 0 2 2 2 0 Synaptobrevin Mito_carr PF00153.22 EDN99403.1 - 1.8e-54 181.4 8.0 1.3e-23 82.4 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EDN99403.1 - 5.2e-22 77.7 8.1 6e-11 42.3 1.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDN99403.1 - 3e-19 66.8 10.3 2.5e-05 23.2 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EDN99403.1 - 9.9e-17 59.2 9.7 0.00085 19.0 0.3 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EDN99403.1 - 7.2e-15 54.3 8.0 1.9e-07 30.6 0.4 3.7 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EDN99403.1 - 1.5e-10 39.9 11.9 6.5e-05 22.0 0.3 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EDN99403.1 - 4.7e-07 29.8 1.6 0.00049 20.1 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Sec23_trunk PF04811.10 EDN99403.1 - 0.053 12.8 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain EF-hand_4 PF12763.2 EDN99403.1 - 0.26 11.0 4.5 0.66 9.7 0.3 2.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EDN99403.1 - 3.3 7.4 5.4 8.9 6.0 0.1 3.7 3 1 2 5 5 5 0 EF hand Cyclin_N PF00134.18 EDN99404.1 - 6.9e-11 41.8 0.0 1.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EDN99404.1 - 0.012 15.4 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin PF08613.6 EDN99404.1 - 0.39 11.1 1.7 1.3 9.4 0.2 2.0 2 0 0 2 2 2 0 Cyclin DUF4452 PF14618.1 EDN99405.1 - 5.2e-47 159.7 12.4 6.6e-47 159.3 8.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Gemini_AL1_M PF08283.6 EDN99406.1 - 0.057 13.2 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 Geminivirus rep protein central domain Zip PF02535.17 EDN99407.1 - 2.7 6.9 6.3 2.8 6.8 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Borrelia_P83 PF05262.6 EDN99407.1 - 4.1 5.5 12.4 4.9 5.3 8.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein UCH PF00443.24 EDN99408.1 - 2.9e-17 62.6 0.0 4.8e-10 39.0 0.0 2.7 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN99408.1 - 0.11 11.9 0.1 3.8 6.8 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.14 EDN99409.1 - 9.8e-41 138.6 0.1 1.2e-40 138.3 0.1 1.0 1 0 0 1 1 1 1 VHS domain Dehydratase_SU PF02287.10 EDN99409.1 - 0.073 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Dehydratase small subunit GAT PF03127.9 EDN99410.1 - 0.075 13.0 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 GAT domain UIM PF02809.15 EDN99410.1 - 1.1 9.0 9.1 0.03 13.8 1.7 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif GTP_EFTU PF00009.22 EDN99411.1 - 1.7e-46 158.0 0.7 3e-46 157.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EDN99411.1 - 3.1e-23 81.6 0.3 6.9e-23 80.5 0.2 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 EDN99411.1 - 6.8e-08 32.5 0.0 1.8e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EDN99411.1 - 3.1e-06 27.2 0.2 1.8e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EDN99411.1 - 1.1e-05 25.2 0.1 0.0002 21.3 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EDN99411.1 - 0.015 15.8 0.3 0.15 12.5 0.0 2.9 2 1 0 2 2 2 0 Miro-like protein HSP70 PF00012.15 EDN99412.1 - 2.5e-268 891.0 15.5 2.8e-268 890.8 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN99412.1 - 6.6e-19 67.6 2.6 1.2e-17 63.4 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EDN99412.1 - 0.0036 16.4 3.5 0.011 14.7 0.1 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase PsbL PF02419.12 EDN99412.1 - 0.2 11.0 2.8 0.43 10.0 1.9 1.5 1 0 0 1 1 1 0 PsbL protein FtsA PF14450.1 EDN99412.1 - 0.59 9.9 8.5 2.1 8.2 1.0 3.7 2 2 0 2 2 2 0 Cell division protein FtsA Fungal_trans_2 PF11951.3 EDN99413.1 - 2.4e-07 29.7 1.3 3.8e-07 29.0 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF791 PF05631.9 EDN99414.1 - 2e-70 237.2 19.7 1.3e-53 181.9 5.6 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EDN99414.1 - 6.3e-27 94.2 26.9 6.3e-27 94.2 18.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.1 EDN99414.1 - 0.22 11.0 0.1 0.22 11.0 0.0 2.8 2 1 1 3 3 3 0 PgaD-like protein Cytochrom_B561 PF03188.11 EDN99414.1 - 0.88 9.4 11.2 0.03 14.1 2.6 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 UCH_1 PF13423.1 EDN99415.1 - 3.4e-33 115.3 0.4 5.2e-33 114.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EDN99415.1 - 1.4e-23 83.9 0.0 2.5e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 EDN99417.1 - 1e-17 64.1 0.0 3.9e-12 45.8 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99417.1 - 3e-06 26.5 0.1 0.0001 21.4 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase DUF605 PF04652.11 EDN99417.1 - 0.033 13.6 20.7 0.038 13.3 14.3 1.1 1 0 0 1 1 1 0 Vta1 like SRP-alpha_N PF04086.8 EDN99417.1 - 0.41 9.9 4.8 0.65 9.3 3.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.4 EDN99417.1 - 3.8 5.6 14.2 4.9 5.2 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 KAR9 PF08580.5 EDN99417.1 - 4.3 5.4 10.5 6.3 4.9 7.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF566 PF04484.7 EDN99417.1 - 5.3 6.4 10.4 7.6 5.9 7.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) SOG2 PF10428.4 EDN99417.1 - 9.1 4.8 9.4 13 4.2 6.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein GTP_EFTU PF00009.22 EDN99418.1 - 1.3e-44 151.9 0.0 2.2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN99418.1 - 1.2e-21 76.6 1.0 2e-21 75.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN99418.1 - 1.2e-07 31.7 1.5 2.6e-07 30.6 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN99418.1 - 9.5e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EDN99418.1 - 0.12 10.9 0.2 0.2 10.3 0.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Ran-binding PF05508.6 EDN99419.1 - 7.4e-120 399.4 0.2 9.6e-120 399.0 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Dfp1_Him1_M PF08630.5 EDN99421.1 - 4.5e-47 158.9 0.0 1e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EDN99421.1 - 1.2e-23 82.5 0.6 2.1e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EDN99421.1 - 0.0016 18.2 0.7 0.017 14.9 0.0 2.7 2 0 0 2 2 2 1 twin BRCT domain Pyrophosphatase PF00719.14 EDN99421.1 - 0.021 14.2 0.1 0.057 12.8 0.1 1.7 1 0 0 1 1 1 0 Inorganic pyrophosphatase BRCT PF00533.21 EDN99421.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-C2H2_2 PF12756.2 EDN99421.1 - 0.062 13.4 0.3 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Peptidase_M24 PF00557.19 EDN99422.1 - 1e-49 168.9 0.0 3.2e-49 167.3 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EDN99422.1 - 6.8e-36 122.6 0.1 2.3e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.13 EDN99422.1 - 0.06 13.8 0.1 0.19 12.1 0.1 1.9 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain APG12 PF04110.8 EDN99423.1 - 2.4e-12 46.8 0.0 6e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like autophagy protein Apg12 Pantoate_transf PF02548.10 EDN99424.1 - 3.9e-102 340.8 0.3 4.5e-102 340.6 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EDN99424.1 - 2.1e-08 33.6 0.3 7.8e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PA PF02225.17 EDN99424.1 - 0.13 11.9 0.4 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 PA domain NanE PF04131.9 EDN99424.1 - 0.15 11.0 0.7 1.5 7.7 0.2 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase UQ_con PF00179.21 EDN99425.1 - 1.6e-33 115.0 0.1 2.1e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEPCK_ATP PF01293.15 EDN99427.1 - 8.7e-215 713.5 0.0 1e-214 713.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EDN99427.1 - 0.022 15.0 0.2 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN99427.1 - 0.099 12.5 0.2 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TRAUB PF08164.7 EDN99429.1 - 0.00049 20.1 0.1 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal ParA PF10609.4 EDN99431.1 - 3.4e-35 119.7 0.6 6e-35 118.9 0.4 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDN99431.1 - 0.00076 18.9 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4537 PF15057.1 EDN99432.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.12 EDN99432.1 - 0.026 14.7 0.4 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 PWWP domain DUF572 PF04502.8 EDN99433.1 - 5.2e-60 203.3 0.1 5.7e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) NYD-SP12_N PF15015.1 EDN99433.1 - 0.0016 16.7 0.6 0.0024 16.1 0.4 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal SIR2 PF02146.12 EDN99434.1 - 8.6e-34 116.7 0.0 7.2e-33 113.7 0.0 1.9 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.5 EDN99434.1 - 0.58 9.7 4.2 5.2 6.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) RVT_1 PF00078.22 EDN99435.1 - 6.1e-09 35.5 0.0 3.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orbi_NS1 PF01718.11 EDN99435.1 - 0.0099 13.9 0.0 0.016 13.2 0.0 1.2 1 0 0 1 1 1 1 Orbivirus non-structural protein NS1, or hydrophobic tubular protein PPDFL PF15060.1 EDN99437.1 - 0.031 14.2 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Differentiation and proliferation regulator ComC PF03047.9 EDN99437.1 - 0.057 12.8 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 COMC family MFS_1 PF07690.11 EDN99438.1 - 1.4e-15 56.8 14.1 1.4e-15 56.8 9.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN99438.1 - 0.0012 17.1 0.1 0.0017 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FixP_N PF14715.1 EDN99438.1 - 8.4 5.8 7.1 5.2 6.5 1.9 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Zn_clus PF00172.13 EDN99439.1 - 0.0021 17.9 8.8 0.0037 17.1 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EDN99439.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Chordopox_A13L PF05961.6 EDN99440.1 - 0.015 15.1 0.2 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein P12 PF12669.2 EDN99440.1 - 0.027 14.6 0.7 0.034 14.3 0.5 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family Glycophorin_A PF01102.13 EDN99440.1 - 0.043 13.5 0.2 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A DUF3930 PF13067.1 EDN99440.1 - 0.045 13.6 0.7 0.05 13.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Vpu PF00558.14 EDN99440.1 - 0.05 13.1 0.1 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Vpu protein IncA PF04156.9 EDN99440.1 - 0.06 12.9 1.0 0.064 12.8 0.7 1.0 1 0 0 1 1 1 0 IncA protein PsbN PF02468.10 EDN99440.1 - 0.072 12.7 1.3 0.093 12.3 0.9 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) NfeD PF01957.13 EDN99440.1 - 0.077 13.1 0.0 0.084 13.0 0.0 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4227 PF14004.1 EDN99440.1 - 0.11 12.3 0.2 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) OppC_N PF12911.2 EDN99440.1 - 0.12 11.8 2.2 0.13 11.6 1.5 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Fijivirus_P9-2 PF06837.6 EDN99440.1 - 0.19 10.8 0.4 0.22 10.6 0.3 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF3317 PF11779.3 EDN99440.1 - 0.3 10.5 2.3 0.39 10.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF1206 PF06724.6 EDN99440.1 - 0.61 9.8 4.9 0.28 10.9 2.0 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) Herpes_glycop_H PF02489.11 EDN99440.1 - 2.1 6.2 4.6 2.2 6.2 3.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Flavokinase PF01687.12 EDN99441.1 - 2e-36 124.5 0.0 2.4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Pkinase PF00069.20 EDN99442.1 - 7.8e-72 241.5 0.0 9.6e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99442.1 - 1.2e-31 109.7 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN99442.1 - 0.003 16.5 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN99442.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN99442.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EDN99442.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EDN99442.1 - 0.16 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amidase PF01425.16 EDN99443.1 - 1e-92 311.3 0.0 1.6e-92 310.6 0.0 1.3 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 EDN99443.1 - 4.9e-24 85.2 0.2 2.1e-23 83.1 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-DHHC PF01529.15 EDN99446.1 - 2.3e-31 108.5 10.8 3.2e-31 108.0 7.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rap1_C PF11626.3 EDN99447.1 - 7.3e-22 77.0 0.3 4.8e-20 71.2 0.0 3.1 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EDN99447.1 - 2.4e-17 62.4 3.2 2.2e-14 52.9 0.7 3.4 3 0 0 3 3 3 2 Rap1 Myb domain ARID PF01388.16 EDN99447.1 - 6.9e-13 48.2 0.0 1.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.5 EDN99447.1 - 1e-05 26.0 5.8 0.021 15.3 0.0 4.0 3 1 0 3 3 3 2 Rap1, DNA-binding BRCT PF00533.21 EDN99447.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3973 PF13119.1 EDN99451.1 - 0.003 17.4 1.0 1.5 8.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3973) PP2C_2 PF13672.1 EDN99451.1 - 0.027 13.8 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C SIMPL PF04402.9 EDN99453.1 - 0.0075 16.1 1.8 0.008 16.0 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Robl_LC7 PF03259.12 EDN99453.1 - 0.4 10.2 3.4 2.5 7.7 0.7 2.0 1 1 1 2 2 2 0 Roadblock/LC7 domain Beta_elim_lyase PF01212.16 EDN99454.1 - 1.2e-48 165.7 0.0 1.4e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase ATPgrasp_Ter PF15632.1 EDN99455.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EDN99456.1 - 1e-13 51.4 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN99456.1 - 0.00082 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN99456.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EDN99456.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EDN99456.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain PTR2 PF00854.16 EDN99457.1 - 9.5e-17 60.8 6.2 1.3e-16 60.3 4.3 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EDN99457.1 - 1.1e-07 30.9 15.1 1.1e-06 27.6 10.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN99457.1 - 0.0011 17.4 1.5 0.0011 17.4 1.1 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein PTR2 PF00854.16 EDN99458.1 - 0.0096 14.7 1.0 0.02 13.6 0.0 1.8 1 1 1 2 2 2 1 POT family MFS_1 PF07690.11 EDN99458.1 - 0.024 13.3 2.9 0.037 12.7 2.0 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4134 PF13572.1 EDN99458.1 - 0.3 11.2 3.2 1 9.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4134) DUF1072 PF06380.6 EDN99458.1 - 0.75 9.5 3.9 1.3 8.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) ABC_tran PF00005.22 EDN99459.1 - 0.0004 20.7 0.0 0.0013 19.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Exo_endo_phos_2 PF14529.1 EDN99460.1 - 0.0064 16.1 0.1 0.022 14.3 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase VCBS PF13517.1 EDN99461.1 - 0.094 13.0 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RIO1 PF01163.17 EDN99462.1 - 1.4e-05 24.5 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDN99462.1 - 0.00014 21.6 0.0 0.0028 17.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2766 PF10964.3 EDN99462.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) Pkinase PF00069.20 EDN99462.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 EDN99462.1 - 0.029 13.4 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Podoplanin PF05808.6 EDN99466.1 - 5.7e-06 25.9 2.6 9.5e-06 25.2 1.8 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 EDN99466.1 - 0.0011 18.1 0.1 0.0034 16.6 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EDN99466.1 - 0.0042 16.5 1.1 0.012 15.0 0.8 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.2 EDN99466.1 - 0.0058 15.8 0.8 0.008 15.4 0.5 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF1517 PF07466.6 EDN99466.1 - 0.031 13.2 2.7 0.063 12.2 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Granulin PF00396.13 EDN99466.1 - 1 9.5 5.7 5.7 7.1 3.9 2.1 1 1 0 1 1 1 0 Granulin Myb_DNA-bind_6 PF13921.1 EDN99467.1 - 0.078 13.0 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain FAD_binding_6 PF00970.19 EDN99468.1 - 2.4e-10 40.4 0.0 4.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDN99468.1 - 2.9e-07 31.0 0.0 0.0002 21.9 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDN99468.1 - 0.00015 21.6 0.0 0.00034 20.5 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain RVT_2 PF07727.9 EDN99469.1 - 7.3e-67 224.9 0.1 1.2e-66 224.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN99469.1 - 2e-14 53.6 0.0 5.8e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN99469.1 - 2.1e-06 27.2 0.0 5.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EDN99469.1 - 0.00014 21.6 0.2 0.00026 20.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 EDN99469.1 - 0.0013 18.2 0.1 0.0037 16.7 0.1 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EDN99469.1 - 0.0015 18.3 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVP PF00077.15 EDN99469.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease HTH_Tnp_Tc5 PF03221.11 EDN99471.1 - 9.2e-15 54.2 0.0 1.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AAA_23 PF13476.1 EDN99472.1 - 1.3 9.2 16.2 2.7 8.2 11.3 1.5 1 0 0 1 1 1 0 AAA domain Flavoprotein PF02441.14 EDN99474.1 - 8.7e-21 73.9 0.0 3.2e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Flavoprotein WEMBL PF05701.6 EDN99477.1 - 0.0018 16.8 9.2 0.052 12.0 1.6 2.2 2 0 0 2 2 2 2 Weak chloroplast movement under blue light Bacillus_HBL PF05791.6 EDN99477.1 - 0.003 16.9 1.0 0.003 16.9 0.7 2.7 2 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DUF2461 PF09365.5 EDN99477.1 - 0.0056 16.1 0.4 0.56 9.5 0.0 2.8 2 1 1 3 3 3 1 Conserved hypothetical protein (DUF2461) Laminin_II PF06009.7 EDN99477.1 - 0.0099 15.6 8.7 0.17 11.6 1.1 2.7 2 1 0 2 2 2 2 Laminin Domain II NPV_P10 PF05531.7 EDN99477.1 - 0.016 15.4 4.8 0.44 10.8 0.1 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MutS_IV PF05190.13 EDN99477.1 - 0.018 15.2 1.5 1.8 8.7 0.1 3.2 3 0 0 3 3 3 0 MutS family domain IV Mnd1 PF03962.10 EDN99477.1 - 0.018 14.6 8.1 0.47 10.0 1.0 2.7 1 1 1 2 2 2 0 Mnd1 family DUF2730 PF10805.3 EDN99477.1 - 0.024 14.3 0.4 0.69 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Myosin_tail_1 PF01576.14 EDN99477.1 - 0.033 11.9 9.0 0.064 10.9 0.3 2.1 2 0 0 2 2 2 0 Myosin tail AAA_13 PF13166.1 EDN99477.1 - 0.035 12.5 6.4 0.04 12.3 3.7 1.6 1 1 0 1 1 1 0 AAA domain Lebercilin PF15619.1 EDN99477.1 - 0.037 13.4 12.3 1.5 8.2 0.4 3.4 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease FliJ PF02050.11 EDN99477.1 - 0.038 14.0 17.5 0.41 10.6 1.2 3.5 3 0 0 3 3 3 0 Flagellar FliJ protein STAT_alpha PF01017.15 EDN99477.1 - 0.054 13.2 11.9 0.45 10.1 1.3 2.9 2 1 0 2 2 2 0 STAT protein, all-alpha domain DUF1409 PF07197.7 EDN99477.1 - 0.058 13.4 0.1 0.42 10.7 0.0 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1409) MCPsignal PF00015.16 EDN99477.1 - 0.12 11.8 2.1 0.26 10.7 0.2 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GAS PF13851.1 EDN99477.1 - 0.13 11.4 16.6 0.22 10.7 3.0 3.4 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding TEX13 PF15186.1 EDN99477.1 - 0.15 11.6 6.0 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family U1snRNP70_N PF12220.3 EDN99477.1 - 0.2 12.0 2.1 4.5 7.6 0.0 2.7 3 0 0 3 3 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TBPIP PF07106.8 EDN99477.1 - 0.25 10.8 13.8 0.73 9.3 1.2 3.8 3 2 2 5 5 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EDN99477.1 - 0.35 10.8 13.3 2.4 8.2 0.0 3.8 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.5 EDN99477.1 - 0.36 10.0 6.7 1.1 8.4 0.5 2.5 2 1 0 2 2 2 0 Vps5 C terminal like Spc7 PF08317.6 EDN99477.1 - 0.44 9.1 11.7 0.66 8.5 1.8 2.3 1 1 2 3 3 3 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EDN99477.1 - 0.48 10.2 10.1 0.34 10.7 0.4 2.9 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Bul1_C PF04426.7 EDN99477.1 - 0.59 9.2 4.7 4.8 6.2 0.1 2.2 2 0 0 2 2 2 0 Bul1 C terminus IncA PF04156.9 EDN99477.1 - 0.62 9.6 6.8 5.6 6.5 4.8 2.2 1 1 0 1 1 1 0 IncA protein HrpB7 PF09486.5 EDN99477.1 - 0.82 9.5 8.2 0.42 10.5 1.1 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 EDN99477.1 - 1.3 8.7 17.4 0.69 9.6 3.2 3.3 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 EDN99477.1 - 1.9 8.9 7.8 17 5.8 0.3 3.7 2 1 1 3 3 3 0 SlyX Tropomyosin_1 PF12718.2 EDN99477.1 - 2 8.2 11.5 0.61 9.9 1.2 2.6 2 1 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.4 EDN99477.1 - 2.5 8.2 12.6 4.2 7.5 0.8 3.6 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 EDN99477.1 - 2.6 8.3 9.8 4.3 7.6 0.3 3.5 2 1 1 3 3 3 0 Spectrin repeat ATG16 PF08614.6 EDN99477.1 - 3.2 7.5 11.4 0.77 9.5 2.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIVA PF05103.8 EDN99477.1 - 3.7 7.5 9.9 1.9 8.5 1.3 2.6 2 1 0 2 2 2 0 DivIVA protein Atg14 PF10186.4 EDN99477.1 - 4.4 6.1 7.7 1 8.2 1.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Rer1 PF03248.8 EDN99479.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 Rer1 family Glyco_hydro_7 PF00840.15 EDN99480.1 - 2.8e-202 671.8 19.4 4.3e-202 671.2 13.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EDN99480.1 - 6.5e-08 32.1 12.7 6.5e-08 32.1 8.8 3.5 3 1 0 3 3 3 1 Fungal cellulose binding domain adh_short_C2 PF13561.1 EDN99482.1 - 2.5e-16 60.2 0.1 7.1e-15 55.4 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN99482.1 - 8.6e-15 55.0 2.1 1.7e-13 50.8 1.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN99482.1 - 2.8e-08 33.6 0.1 4.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN99482.1 - 0.0023 16.8 0.1 0.005 15.7 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EDN99482.1 - 0.063 13.2 0.2 0.25 11.3 0.1 2.0 1 1 1 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 EDN99482.1 - 0.081 11.6 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EDN99482.1 - 0.086 11.8 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EDN99482.1 - 0.11 12.6 0.5 0.27 11.3 0.2 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EDN99482.1 - 0.12 11.8 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family BUD22 PF09073.5 EDN99483.1 - 1.4e-121 406.5 34.4 4.1e-121 405.0 23.8 1.7 1 1 0 1 1 1 1 BUD22 DUF605 PF04652.11 EDN99483.1 - 2.3 7.5 28.1 0.17 11.2 16.2 1.5 2 0 0 2 2 2 0 Vta1 like Chal_sti_synt_N PF00195.14 EDN99484.1 - 1.8e-21 76.4 0.5 2.9e-21 75.7 0.3 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EDN99484.1 - 2.1e-21 76.4 0.0 4.5e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EDN99484.1 - 3.4e-06 26.3 0.2 5.4e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EDN99484.1 - 3.8e-06 26.8 0.0 0.00013 21.8 0.0 2.6 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EDN99484.1 - 0.002 17.7 0.2 0.0058 16.2 0.1 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans_2 PF11951.3 EDN99485.1 - 8.5e-05 21.3 0.1 0.00012 20.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN99485.1 - 0.00094 19.0 0.8 0.0018 18.1 0.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EDN99486.1 - 4.6e-50 170.4 0.0 6.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM86 PF14904.1 EDN99487.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Glyco_hydro_71 PF03659.9 EDN99493.1 - 5e-83 278.7 15.0 4.9e-53 179.9 4.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 HEAT_2 PF13646.1 EDN99497.1 - 1.1e-21 76.8 7.5 4.3e-05 23.7 0.1 7.7 5 3 2 7 7 7 6 HEAT repeats HEAT PF02985.17 EDN99497.1 - 1.6e-21 74.3 3.8 0.0018 18.2 0.0 9.5 10 0 0 10 10 9 4 HEAT repeat HEAT_EZ PF13513.1 EDN99497.1 - 1.2e-17 63.8 9.2 0.0006 20.2 0.0 10.3 10 1 2 12 12 10 4 HEAT-like repeat Adaptin_N PF01602.15 EDN99497.1 - 1.2e-09 37.0 0.0 0.11 10.7 0.0 4.3 3 1 0 4 4 4 4 Adaptin N terminal region IBN_N PF03810.14 EDN99497.1 - 1e-08 34.9 4.9 4.3e-07 29.7 1.4 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 EDN99497.1 - 3.6e-08 32.9 2.1 0.00023 20.8 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EDN99497.1 - 4.9e-08 33.2 0.0 5.5 7.4 0.0 6.1 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EDN99497.1 - 3.1e-07 29.4 1.5 0.042 12.5 0.0 4.7 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 EDN99497.1 - 7e-07 29.2 1.1 2.3 8.0 0.0 6.2 6 2 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDN99497.1 - 9.7e-07 28.3 0.8 0.06 12.6 0.0 5.7 5 2 2 7 7 7 1 CLASP N terminal ParcG PF10274.4 EDN99497.1 - 1.8e-06 27.9 0.3 0.21 11.4 0.0 5.3 4 2 1 6 6 6 1 Parkin co-regulated protein UME PF08064.8 EDN99497.1 - 2.3e-05 24.2 0.0 0.19 11.6 0.0 4.5 5 0 0 5 5 4 1 UME (NUC010) domain IFRD PF05004.8 EDN99497.1 - 0.0011 18.0 0.8 0.19 10.7 0.0 3.6 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) BP28CT PF08146.7 EDN99497.1 - 0.0015 18.2 2.6 1.2 8.9 0.1 4.4 4 1 0 4 4 4 1 BP28CT (NUC211) domain MutS_III PF05192.13 EDN99497.1 - 0.0025 17.6 0.3 0.074 12.8 0.1 3.0 2 2 0 2 2 2 1 MutS domain III DUF577 PF04510.7 EDN99497.1 - 0.015 15.0 0.0 0.22 11.1 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF577) TipAS PF07739.8 EDN99497.1 - 0.017 15.4 1.4 11 6.4 0.5 4.0 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain HEAT_PBS PF03130.11 EDN99497.1 - 0.65 10.6 5.8 4.8 7.9 0.1 4.5 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat RVT_1 PF00078.22 EDN99500.1 - 8.2e-17 61.2 0.0 9.1e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PG_binding_3 PF09374.5 EDN99500.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PHBC_N PF12551.3 EDN99501.1 - 0.027 14.0 0.4 0.037 13.5 0.3 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal KR PF08659.5 EDN99502.1 - 1.1e-55 188.1 0.3 3.3e-55 186.5 0.2 1.9 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 EDN99502.1 - 5.6e-54 183.2 0.1 1.3e-53 182.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EDN99502.1 - 5.6e-45 153.7 0.0 2.6e-43 148.2 0.0 3.0 2 1 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EDN99502.1 - 3.6e-44 151.3 0.1 4.6e-43 147.7 0.1 2.3 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EDN99502.1 - 3.5e-42 144.1 1.1 1.4e-41 142.1 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDN99502.1 - 5.6e-38 129.4 0.0 1.6e-37 127.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EDN99502.1 - 9.6e-20 70.4 0.0 3.3e-19 68.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EDN99502.1 - 2.2e-15 56.7 0.1 3.6e-14 52.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN99502.1 - 5.8e-14 52.3 0.0 3e-13 50.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EDN99502.1 - 5.4e-13 49.9 0.0 4.7e-12 46.9 0.0 2.8 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EDN99502.1 - 5.4e-12 45.5 0.0 2.1e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN99502.1 - 5.2e-11 42.8 0.0 2e-10 41.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN99502.1 - 4.2e-10 40.2 0.0 1.8e-09 38.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EDN99502.1 - 3.3e-06 26.8 0.6 1e-05 25.2 0.4 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EDN99502.1 - 3.4e-06 26.3 0.0 7.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EDN99502.1 - 6e-06 26.4 0.5 5.7e-05 23.3 0.1 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EDN99502.1 - 4.7e-05 22.5 0.1 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EDN99502.1 - 0.00021 21.2 0.0 0.0038 17.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDN99502.1 - 0.0017 17.7 0.0 0.0091 15.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain ACP_syn_III PF08545.5 EDN99502.1 - 0.015 14.9 0.4 0.049 13.2 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Shikimate_DH PF01488.15 EDN99502.1 - 0.053 13.6 0.1 0.32 11.0 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EDN99502.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DREV PF05219.7 EDN99502.1 - 0.35 9.6 0.0 0.7 8.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF915 PF06028.6 EDN99502.1 - 1.2 8.1 0.0 2.1 7.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 EDN99504.1 - 1e-26 93.5 46.1 2.4e-24 85.7 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF829 PF05705.9 EDN99505.1 - 2.3e-38 132.2 0.0 6.9e-38 130.6 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EDN99505.1 - 0.0015 18.4 0.8 0.0027 17.6 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CFEM PF05730.6 EDN99507.1 - 6.5e-16 57.9 12.0 1e-15 57.2 8.3 1.3 1 0 0 1 1 1 1 CFEM domain p450 PF00067.17 EDN99509.1 - 2.4e-39 135.1 0.0 3.4e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_12 PF01670.11 EDN99515.1 - 2.2e-35 121.7 1.6 4.2e-35 120.8 1.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.13 EDN99515.1 - 0.15 11.7 10.2 0.096 12.3 4.5 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain Hamartin PF04388.7 EDN99515.1 - 3.1 6.3 9.1 4.4 5.8 6.3 1.3 1 0 0 1 1 1 0 Hamartin protein DUF3439 PF11921.3 EDN99515.1 - 3.2 7.5 20.0 8.2 6.2 13.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_72 PF03198.9 EDN99516.1 - 2.1e-116 388.3 0.0 2.8e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EDN99516.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pex14_N PF04695.8 EDN99516.1 - 0.018 15.0 2.9 0.032 14.2 2.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EDN99516.1 - 1.5 7.0 11.9 1.8 6.7 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PRMT5 PF05185.11 EDN99518.1 - 1.9e-168 561.0 0.0 2.6e-168 560.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EDN99518.1 - 0.02 14.5 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF866 PF05907.8 EDN99519.1 - 2.2e-44 150.8 0.1 5.6e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 EDN99519.1 - 2.6e-11 42.8 0.0 4.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain BSD PF03909.12 EDN99519.1 - 0.14 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 BSD domain Zn_Tnp_IS1595 PF12760.2 EDN99519.1 - 0.3 10.9 2.1 0.72 9.7 1.5 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF2419 PF10343.4 EDN99521.1 - 2e-119 398.0 0.2 2.6e-119 397.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EDN99522.1 - 2.7e-42 143.7 0.1 5.5e-42 142.8 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EDN99522.1 - 2.3e-30 103.9 0.1 4.4e-30 103.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EDN99522.1 - 3.7e-24 84.6 1.7 1.5e-23 82.6 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EDN99522.1 - 3e-18 64.9 1.1 3e-18 64.9 0.8 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EDN99522.1 - 8.2e-05 22.7 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDN99522.1 - 0.0071 16.4 0.1 0.021 14.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EDN99522.1 - 0.07 13.5 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EDN99523.1 - 5.7e-16 58.8 6.8 9.7e-08 32.0 0.4 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99523.1 - 1.6e-07 31.3 0.4 9.5e-05 22.2 0.3 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN99523.1 - 0.00085 19.0 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4350 PF14258.1 EDN99523.1 - 0.027 14.6 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) KR PF08659.5 EDN99523.1 - 0.062 12.9 2.3 0.75 9.4 1.5 2.5 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 EDN99523.1 - 0.13 11.6 0.0 0.57 9.5 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP-grasp_2 PF08442.5 EDN99524.1 - 1.5e-07 30.9 0.0 2.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EDN99525.1 - 3.6e-18 65.4 0.0 1.5e-15 56.7 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EDN99525.1 - 3.8e-18 65.8 0.1 3e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EDN99525.1 - 3.5e-14 52.6 0.1 7e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EDN99525.1 - 9.7e-06 25.2 0.0 0.0004 19.9 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 EDN99525.1 - 0.16 11.3 0.0 0.44 9.9 0.0 1.7 1 0 0 1 1 1 0 CEP-1, DNA binding Med13_C PF06333.7 EDN99526.1 - 2 6.8 5.5 2.2 6.7 3.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal ABC_tran PF00005.22 EDN99528.1 - 1.5e-27 96.5 0.3 2.8e-27 95.6 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_16 PF13191.1 EDN99528.1 - 3.3e-07 30.4 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EDN99528.1 - 9.5e-07 29.0 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDN99528.1 - 3.7e-06 26.4 0.2 1.1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN99528.1 - 4.1e-06 26.0 0.0 7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EDN99528.1 - 0.00031 20.8 0.1 0.0068 16.5 0.0 2.4 1 1 1 2 2 2 1 RNA helicase AAA PF00004.24 EDN99528.1 - 0.00054 20.1 0.1 0.0016 18.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN99528.1 - 0.00079 19.5 0.1 0.0019 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN99528.1 - 0.0009 18.9 0.5 0.0021 17.7 0.3 1.7 1 1 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EDN99528.1 - 0.00095 18.9 0.2 0.0097 15.6 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase Rad17 PF03215.10 EDN99528.1 - 0.0011 17.7 0.0 0.0014 17.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein T2SE PF00437.15 EDN99528.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EDN99528.1 - 0.0019 18.1 0.3 0.0075 16.2 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EDN99528.1 - 0.002 18.1 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDN99528.1 - 0.0022 17.6 0.1 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EDN99528.1 - 0.0043 17.8 0.0 0.0087 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN99528.1 - 0.0043 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDN99528.1 - 0.0074 16.1 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN99528.1 - 0.0081 15.6 0.7 0.026 13.9 0.1 2.0 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EDN99528.1 - 0.0089 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDN99528.1 - 0.011 15.2 0.1 0.03 13.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EDN99528.1 - 0.011 15.3 0.3 0.017 14.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 EDN99528.1 - 0.011 14.9 0.0 0.04 13.1 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EDN99528.1 - 0.012 15.2 0.1 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EDN99528.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EDN99528.1 - 0.02 14.3 0.1 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EDN99528.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA-like domain ATP-synt_ab PF00006.20 EDN99528.1 - 0.027 13.9 0.2 0.047 13.1 0.1 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 EDN99528.1 - 0.027 14.3 0.0 0.094 12.6 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RuvB_N PF05496.7 EDN99528.1 - 0.036 13.1 0.2 0.077 12.0 0.1 1.6 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 EDN99528.1 - 0.036 13.5 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EDN99528.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EDN99528.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EDN99528.1 - 0.1 12.3 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 NTPase DUF2791 PF10923.3 EDN99528.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ABC2_membrane PF01061.19 EDN99529.1 - 5e-27 94.4 25.9 6e-27 94.1 18.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EDN99529.1 - 0.00031 19.9 20.6 0.0004 19.5 14.3 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2304 PF10066.4 EDN99529.1 - 0.41 10.5 2.9 0.46 10.3 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) TMPIT PF07851.8 EDN99529.1 - 0.58 9.1 4.5 0.83 8.6 3.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein HeLo PF14479.1 EDN99530.1 - 5e-46 157.1 3.8 7.6e-46 156.5 2.7 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EDN99530.1 - 1.3e-05 24.4 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EDN99530.1 - 3.2e-05 23.1 0.1 0.0001 21.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Fungal_trans PF04082.13 EDN99531.1 - 1.9e-07 30.2 0.0 3.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN99531.1 - 9.5e-06 25.4 7.7 1.9e-05 24.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.16 EDN99532.1 - 4.6e-23 81.4 8.6 4.6e-23 81.4 6.0 1.9 1 1 1 2 2 2 1 Snf7 GAS PF13851.1 EDN99532.1 - 0.92 8.6 9.0 0.52 9.4 3.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CS PF04969.11 EDN99533.1 - 2.5e-06 27.9 0.2 4.2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 CS domain Xol-1_GHMP-like PF09109.5 EDN99533.1 - 0.3 11.1 2.3 0.39 10.7 1.0 1.5 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like PAP2 PF01569.16 EDN99534.1 - 2.6e-08 33.6 17.1 2.1e-07 30.6 11.8 2.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EDN99534.1 - 1.4e-06 27.9 3.8 2.5e-06 27.1 2.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EDN99534.1 - 1.1 9.6 6.3 0.22 11.7 1.1 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Skp1_POZ PF03931.10 EDN99536.1 - 1.4e-11 44.3 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Pou PF00157.12 EDN99536.1 - 0.051 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Amidase PF01425.16 EDN99538.1 - 2.2e-70 237.7 0.0 1.3e-51 175.8 0.2 2.0 1 1 1 2 2 2 2 Amidase AF0941-like PF14591.1 EDN99538.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AF0941-like IncA PF04156.9 EDN99539.1 - 0.021 14.4 4.2 0.026 14.1 2.9 1.1 1 0 0 1 1 1 0 IncA protein KfrA_N PF11740.3 EDN99539.1 - 0.042 14.2 5.5 0.06 13.8 3.8 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term T2SK PF03934.8 EDN99539.1 - 0.075 12.1 0.0 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein K Pex14_N PF04695.8 EDN99539.1 - 0.27 11.2 1.6 0.49 10.4 1.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAGE_N PF12440.3 EDN99539.1 - 0.34 11.2 7.7 0.66 10.3 5.4 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal CAP_N PF01213.14 EDN99539.1 - 0.66 9.2 7.8 0.96 8.6 5.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EDN99539.1 - 1.9 7.8 8.1 2.8 7.2 5.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EDN99540.1 - 2.5e-05 23.1 0.2 2.9e-05 22.9 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Arrestin_N PF00339.24 EDN99541.1 - 1.3e-12 47.8 0.0 3e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EDN99541.1 - 1.5e-11 44.5 0.0 4.1e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EDN99541.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like MRP-L20 PF12824.2 EDN99543.1 - 0.0042 17.0 1.5 0.0096 15.8 1.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Yos1 PF08571.5 EDN99543.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Yos1-like Cpn60_TCP1 PF00118.19 EDN99544.1 - 1.6e-147 492.0 5.2 1.9e-147 491.8 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_28 PF00295.12 EDN99545.1 - 4e-18 65.4 4.8 8.8e-15 54.4 3.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 zf-C2H2 PF00096.21 EDN99548.1 - 8.2e-09 35.2 6.9 4.5e-05 23.5 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN99548.1 - 6.4e-07 29.2 9.7 0.0032 17.6 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN99548.1 - 6.2e-05 22.7 6.1 0.008 16.0 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN99548.1 - 0.00036 20.5 1.5 0.29 11.3 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DinB PF05163.7 EDN99548.1 - 0.012 15.3 4.7 2.5 7.8 2.5 2.6 2 0 0 2 2 2 0 DinB family zf-met PF12874.2 EDN99548.1 - 0.013 15.6 1.8 1.7 8.9 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN99548.1 - 0.081 13.0 6.4 5.1 7.2 0.5 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EDN99548.1 - 0.5 10.7 3.5 50 4.4 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain IncA PF04156.9 EDN99548.1 - 2.5 7.6 7.9 5.9 6.4 5.5 1.7 1 0 0 1 1 1 0 IncA protein MIP PF00230.15 EDN99549.1 - 1.8e-25 89.7 7.1 2.7e-25 89.1 4.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein SKIP_SNW PF02731.10 EDN99550.1 - 4 6.8 9.1 1.2 8.6 0.8 2.7 3 0 0 3 3 3 0 SKIP/SNW domain Gly_transf_sug PF04488.10 EDN99551.1 - 5.8e-09 36.2 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EDN99551.1 - 0.022 13.2 0.1 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain His_Phos_1 PF00300.17 EDN99552.1 - 3.7e-12 46.6 0.1 7.1e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ABC2_membrane PF01061.19 EDN99553.1 - 1.8e-68 229.8 42.5 7e-50 169.1 18.3 3.3 2 1 1 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.22 EDN99553.1 - 1.8e-34 118.9 0.0 4.7e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EDN99553.1 - 3.7e-34 116.4 5.3 1e-30 105.3 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EDN99553.1 - 1.1e-23 83.0 0.0 2.8e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EDN99553.1 - 1.9e-07 30.7 0.1 8.4e-05 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN99553.1 - 9.6e-06 25.6 1.3 0.00036 20.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EDN99553.1 - 4.3e-05 22.7 0.1 0.0043 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDN99553.1 - 0.00021 20.7 1.2 0.03 13.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDN99553.1 - 0.00024 20.9 0.1 0.025 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EDN99553.1 - 0.0019 17.4 0.0 0.18 11.0 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EDN99553.1 - 0.0064 16.6 0.2 1.2 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDN99553.1 - 0.0089 16.3 0.1 0.58 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN99553.1 - 0.012 16.4 0.0 0.68 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDN99553.1 - 0.013 14.9 2.3 0.14 11.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EDN99553.1 - 0.015 15.0 1.7 1.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain ABC2_membrane_3 PF12698.2 EDN99553.1 - 0.017 14.2 34.5 0.0096 14.9 9.1 3.9 2 2 1 3 3 3 0 ABC-2 family transporter protein NACHT PF05729.7 EDN99553.1 - 0.022 14.4 0.8 1.7 8.2 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EDN99553.1 - 0.037 13.9 0.1 1.6 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EDN99553.1 - 0.11 12.1 0.1 0.97 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EDN99553.1 - 0.16 11.9 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EDN99553.1 - 0.17 11.5 0.0 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase H2TH PF06831.9 EDN99554.1 - 2.1e-21 75.4 0.0 4.6e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EDN99554.1 - 2.1e-08 34.5 0.1 1.6e-06 28.4 0.0 2.5 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 EDN99554.1 - 0.00091 17.8 0.0 0.002 16.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PEX11 PF05648.9 EDN99555.1 - 4.4e-76 255.0 0.3 4.9e-76 254.8 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.3 EDN99555.1 - 0.18 11.8 0.4 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) SpoVAB PF13782.1 EDN99557.1 - 0.51 10.3 6.5 0.21 11.6 2.2 2.0 1 1 1 2 2 2 0 Stage V sporulation protein AB DUF4448 PF14610.1 EDN99558.1 - 0.00012 21.5 0.1 0.00032 20.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EDN99558.1 - 0.024 13.9 1.0 0.059 12.7 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EDN99558.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EDN99558.1 - 0.17 11.5 2.2 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family zf-Nse PF11789.3 EDN99561.1 - 3.1e-18 65.0 1.5 3.1e-18 65.0 1.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN99561.1 - 0.0048 16.5 0.2 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger OPA3 PF07047.7 EDN99561.1 - 0.042 13.6 1.7 0.12 12.1 1.2 1.8 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) zf-MIZ PF02891.15 EDN99561.1 - 0.18 11.3 0.4 0.46 10.0 0.2 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger NUDIX PF00293.23 EDN99562.1 - 5.7e-12 45.4 0.9 1.1e-11 44.4 0.6 1.4 1 1 0 1 1 1 1 NUDIX domain MitMem_reg PF13012.1 EDN99563.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function RNase_H PF00075.19 EDN99564.1 - 3.2e-13 50.1 0.0 6.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDN99564.1 - 0.0046 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase L1R_F9L PF02442.12 EDN99565.1 - 0.022 14.2 0.1 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Methyltransf_FA PF12248.3 EDN99565.1 - 0.055 13.4 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase DcuA_DcuB PF03605.9 EDN99565.1 - 0.16 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter WD40 PF00400.27 EDN99566.1 - 1.6e-109 354.3 29.4 1.6e-15 56.2 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat NACHT PF05729.7 EDN99566.1 - 2.6e-13 49.9 1.8 6e-07 29.2 0.1 2.4 1 1 1 2 2 2 2 NACHT domain DUF1258 PF06869.7 EDN99566.1 - 3.1e-10 39.5 0.3 1.5 7.8 0.0 6.7 1 1 5 6 6 6 3 Protein of unknown function (DUF1258) Gmad1 PF10647.4 EDN99566.1 - 5.9e-10 38.9 44.7 0.00012 21.5 2.0 4.3 1 1 5 6 6 6 6 Lipoprotein LpqB beta-propeller domain PGAP1 PF07819.8 EDN99566.1 - 7.3e-08 32.2 0.1 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein PD40 PF07676.7 EDN99566.1 - 1.5e-07 30.8 8.2 23 4.8 0.0 7.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF676 PF05057.9 EDN99566.1 - 0.00094 18.5 0.0 0.004 16.4 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDN99566.1 - 0.014 15.2 0.0 0.054 13.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Neil1-DNA_bind PF09292.5 EDN99566.1 - 0.045 13.5 0.2 1.5 8.6 0.2 2.7 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind AAA_19 PF13245.1 EDN99566.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain zf-DHHC PF01529.15 EDN99568.1 - 0.0053 16.1 0.2 0.016 14.5 0.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMC PF07810.8 EDN99568.1 - 0.021 15.2 0.8 0.07 13.5 0.1 2.1 2 0 0 2 2 2 0 TMC domain RSN1_TM PF13967.1 EDN99568.1 - 0.029 13.9 0.8 0.051 13.1 0.5 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport SdpI PF13630.1 EDN99568.1 - 0.044 13.4 1.8 0.092 12.4 1.3 1.6 1 1 0 1 1 1 0 SdpI/YhfL protein family UPF0560 PF10577.4 EDN99568.1 - 0.18 10.0 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4282 PF14110.1 EDN99568.1 - 1.1 9.5 7.3 2.1 8.5 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) DDE_1 PF03184.14 EDN99569.1 - 2.5e-37 128.1 0.0 4.2e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDN99569.1 - 0.016 15.1 7.3 0.031 14.2 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle NPV_P10 PF05531.7 EDN99570.1 - 0.012 15.8 1.9 0.28 11.4 0.4 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2316 PF10078.4 EDN99570.1 - 0.045 13.7 0.5 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) WEMBL PF05701.6 EDN99570.1 - 0.086 11.2 3.3 0.075 11.4 1.1 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF1664 PF07889.7 EDN99570.1 - 0.12 12.1 6.9 0.03 14.1 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.4 EDN99570.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) RVT_2 PF07727.9 EDN99571.1 - 1.6e-70 236.9 0.0 2.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN99571.1 - 2.5e-11 43.7 0.0 8.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN99571.1 - 2e-08 33.7 0.0 6.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN99571.1 - 2.8e-05 23.8 0.4 6.2e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN99571.1 - 0.00037 20.0 0.6 0.00037 20.0 0.4 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN99571.1 - 0.0044 16.4 3.0 0.0044 16.4 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-Sec23_Sec24 PF04810.10 EDN99571.1 - 0.034 13.7 0.1 6.3 6.4 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger CTV_P6 PF06706.6 EDN99572.1 - 0.031 13.7 0.8 0.036 13.5 0.5 1.2 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Sugar_tr PF00083.19 EDN99574.1 - 1.2e-30 106.5 33.3 3.6e-18 65.3 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN99574.1 - 1.3e-15 57.0 41.8 9.1e-10 37.7 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gp5_OB PF06714.6 EDN99574.1 - 0.25 11.3 0.8 0.65 10.0 0.4 1.8 2 0 0 2 2 2 0 Gp5 N-terminal OB domain DUF21 PF01595.15 EDN99574.1 - 9.7 5.4 6.8 25 4.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 DDE_1 PF03184.14 EDN99575.1 - 5.5e-29 100.8 0.6 3.2e-27 95.1 0.1 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EDN99575.1 - 8.2e-06 25.6 0.1 2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EDN99575.1 - 0.026 14.6 0.1 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_Tc5 PF03221.11 EDN99575.1 - 0.064 13.0 0.1 0.064 13.0 0.0 2.2 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Lipoprotein_15 PF03640.10 EDN99578.1 - 0.085 12.3 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Secreted repeat of unknown function Mito_carr PF00153.22 EDN99579.1 - 5.2e-56 186.3 4.3 4.4e-20 71.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ARID PF01388.16 EDN99580.1 - 8.5e-20 70.4 0.0 2.7e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SelR PF01641.13 EDN99584.1 - 1.1e-49 167.2 0.2 1.3e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EDN99584.1 - 0.002 17.8 0.5 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 EDN99584.1 - 0.02 14.8 0.6 2.1 8.3 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 EDN99584.1 - 0.051 12.9 1.0 0.39 10.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 EDN99584.1 - 0.074 13.1 0.4 0.19 11.7 0.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EDN99584.1 - 0.08 12.7 3.1 2.3 8.1 2.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EDN99584.1 - 5.1 6.6 5.4 27 4.3 0.1 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit ArfGap PF01412.13 EDN99585.1 - 1.1e-39 134.8 2.7 1.6e-39 134.2 1.9 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SNARE PF05739.14 EDN99586.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SNARE domain Lyase_1 PF00206.15 EDN99587.1 - 1.9e-23 83.1 0.0 3e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EDN99587.1 - 3.8e-14 52.4 0.0 1.4e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF500 PF04366.7 EDN99588.1 - 1.2e-44 150.8 0.5 2.1e-44 149.9 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_2 PF07653.12 EDN99588.1 - 3e-15 55.4 0.4 3.4e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EDN99588.1 - 1.7e-13 49.7 0.2 5.1e-13 48.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EDN99588.1 - 3.9e-13 48.7 0.1 8e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain adh_short PF00106.20 EDN99591.1 - 3.4e-30 105.1 1.2 3.4e-30 105.1 0.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99591.1 - 2.2e-28 99.6 0.6 3.4e-28 99.0 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99591.1 - 1.4e-15 57.4 0.4 2.3e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN99591.1 - 1.5e-05 24.5 0.3 5e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EDN99591.1 - 0.00039 20.0 1.5 0.001 18.7 0.1 2.4 3 0 0 3 3 3 1 PA domain Polysacc_synt_2 PF02719.10 EDN99591.1 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EDN99591.1 - 0.0079 14.9 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0236 PF06782.6 EDN99591.1 - 0.21 9.9 0.1 0.28 9.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) KH_1 PF00013.24 EDN99592.1 - 3.6e-84 276.3 25.5 1.5e-12 46.9 0.6 11.3 11 1 0 11 11 11 8 KH domain KH_3 PF13014.1 EDN99592.1 - 1.1e-56 187.6 26.9 1.4e-09 37.3 0.0 11.4 12 0 0 12 12 12 8 KH domain KH_2 PF07650.12 EDN99592.1 - 6.4e-10 38.4 24.4 0.016 14.7 0.1 8.1 8 0 0 8 8 8 4 KH domain SLS PF14611.1 EDN99592.1 - 2.3e-05 23.8 10.6 0.08 12.3 0.0 6.4 6 3 2 9 9 9 2 Mitochondrial inner-membrane-bound regulator YjcZ PF13990.1 EDN99592.1 - 0.21 10.6 1.3 0.59 9.2 0.9 1.7 1 0 0 1 1 1 0 YjcZ-like protein Pkinase PF00069.20 EDN99594.1 - 3.2e-72 242.8 0.0 5.1e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99594.1 - 2.3e-45 154.6 0.0 3.9e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDN99594.1 - 1e-18 67.4 0.2 1e-18 67.4 0.2 2.9 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EDN99594.1 - 4.6e-07 29.0 0.0 7.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN99594.1 - 0.013 15.2 0.0 0.059 13.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EDN99594.1 - 0.11 11.5 0.2 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EDN99594.1 - 0.16 11.1 0.1 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain Aldo_ket_red PF00248.16 EDN99597.1 - 5e-53 179.7 0.0 5.7e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.10 EDN99597.1 - 0.0023 17.6 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain Aminotran_3 PF00202.16 EDN99598.1 - 2.4e-98 329.1 0.0 2.8e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III E1-E2_ATPase PF00122.15 EDN99600.1 - 8.7e-46 155.7 0.2 3.9e-45 153.6 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDN99600.1 - 3.9e-36 125.4 0.0 6.5e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EDN99600.1 - 2.7e-19 69.0 0.0 3.5e-08 33.4 0.1 4.4 4 0 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.2 EDN99600.1 - 2.9e-15 56.9 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN99600.1 - 0.00078 19.0 0.2 0.00078 19.0 0.1 2.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Flavi_NS4A PF01350.12 EDN99604.1 - 1.7 8.2 4.8 6.2 6.3 1.4 2.3 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A ArabFuran-catal PF09206.6 EDN99605.1 - 5.2e-139 462.7 18.4 8.2e-139 462.0 12.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EDN99605.1 - 4.1e-63 211.3 3.9 7.1e-63 210.5 2.7 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) FtsJ PF01728.14 EDN99609.1 - 7.4e-45 153.1 0.0 8.6e-44 149.6 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 EDN99610.1 - 1e-42 145.4 0.0 1.9e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN99610.1 - 1.2e-20 73.1 2.0 1.5e-20 72.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN99610.1 - 0.0017 17.2 0.1 0.0032 16.3 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EDN99610.1 - 0.0032 15.9 0.0 1.8 6.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) DUF3354 PF11834.3 EDN99610.1 - 0.054 13.1 0.7 0.13 11.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) AAA_22 PF13401.1 EDN99610.1 - 0.093 12.8 0.3 0.34 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain IPK PF03770.11 EDN99611.1 - 1e-53 181.9 0.0 2.8e-53 180.4 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase LRR_4 PF12799.2 EDN99613.1 - 2.6e-21 74.7 25.6 8.4e-10 38.0 0.7 6.8 5 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN99613.1 - 4.6e-11 42.3 28.1 0.00014 21.5 2.1 6.0 2 1 5 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EDN99613.1 - 9.2e-06 25.0 32.3 0.18 11.9 0.0 11.1 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.1 EDN99613.1 - 0.0064 16.4 20.9 3.6 7.9 0.0 7.7 6 3 2 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 EDN99613.1 - 0.025 14.7 26.7 0.53 10.7 0.1 9.2 9 1 1 10 10 10 0 Leucine rich repeat LRR_9 PF14580.1 EDN99613.1 - 0.42 10.1 2.9 5.3 6.5 0.2 2.8 2 0 0 2 2 2 0 Leucine-rich repeat Menin PF05053.8 EDN99613.1 - 5 5.1 8.6 12 3.9 6.0 1.6 1 0 0 1 1 1 0 Menin ECH PF00378.15 EDN99614.1 - 1.4e-24 86.5 0.0 1.7e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EDN99614.1 - 0.0071 16.1 0.0 0.055 13.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 Glycos_transf_1 PF00534.15 EDN99615.1 - 5.7e-32 110.4 0.2 4e-31 107.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN99615.1 - 5.9e-08 32.9 0.1 1.4e-06 28.5 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDN99615.1 - 1.9e-06 27.7 0.0 2.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDN99615.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EDN99615.1 - 3.8e-05 23.8 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox_3 PF13738.1 EDN99616.1 - 1.3e-19 71.0 0.0 9.7e-19 68.2 0.0 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN99616.1 - 2.1e-05 24.3 0.0 0.0014 18.4 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EDN99616.1 - 0.0027 16.7 0.0 1.5 7.7 0.0 2.8 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN99616.1 - 0.0038 17.1 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ASL_C PF08328.6 EDN99616.1 - 0.15 11.8 0.0 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Kinesin PF00225.18 EDN99622.1 - 8.2e-89 297.5 0.1 5.1e-88 294.9 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain ORC6 PF05460.8 EDN99626.1 - 3.2e-17 62.6 1.3 3.7e-17 62.4 0.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 EDN99628.1 - 6e-08 31.9 2.4 0.00058 19.5 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EDN99628.1 - 6.6e-05 21.9 0.4 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EDN99628.1 - 0.00012 22.1 1.2 0.00012 22.1 0.9 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EDN99628.1 - 0.0012 18.0 0.6 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDN99628.1 - 0.012 15.1 2.0 0.072 12.7 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain pair DENN PF02141.16 EDN99632.1 - 2.1e-40 138.4 0.1 3.8e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EDN99632.1 - 0.00019 21.3 0.0 0.00061 19.7 0.0 2.0 1 0 0 1 1 1 1 uDENN domain LPP PF04728.8 EDN99632.1 - 0.007 16.1 0.6 0.017 14.9 0.4 1.6 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Elongin_A PF06881.6 EDN99632.1 - 0.0092 16.3 4.9 0.0092 16.3 3.4 2.4 1 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TPR_12 PF13424.1 EDN99633.1 - 3e-08 33.4 0.0 4.4e-07 29.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDN99633.1 - 2.2e-05 24.1 0.0 0.27 11.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Vac_Fusion PF02346.11 EDN99633.1 - 0.051 13.0 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein AAA_16 PF13191.1 EDN99634.1 - 0.0097 15.9 0.4 0.013 15.5 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EDN99634.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EDN99634.1 - 0.036 13.8 0.2 0.076 12.7 0.2 1.8 1 1 0 1 1 1 0 Part of AAA domain ERCC4 PF02732.10 EDN99635.1 - 1.2e-23 83.4 1.6 2.4e-23 82.4 1.1 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF3371 PF11851.3 EDN99635.1 - 0.0067 17.1 3.1 0.1 13.2 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3371) peroxidase PF00141.18 EDN99637.1 - 3.9e-18 65.7 0.1 7.8e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Peroxidase Myb_DNA-bind_6 PF13921.1 EDN99639.1 - 4.3e-08 33.1 0.2 0.00092 19.2 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN99639.1 - 0.00064 19.7 0.2 0.26 11.3 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN99641.1 - 3.9e-12 46.0 0.6 2e-06 27.7 0.2 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN99641.1 - 1.3e-11 44.4 0.2 4.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Fibrinogen_BP PF08017.6 EDN99642.1 - 0.031 12.4 28.2 0.038 12.2 19.6 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein CAF-1_p150 PF11600.3 EDN99642.1 - 0.08 12.3 66.5 0.11 11.8 46.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 EDN99642.1 - 0.49 9.6 43.8 0.6 9.3 30.3 1.1 1 0 0 1 1 1 0 SprA-related family Dsh_C PF12316.3 EDN99642.1 - 1.7 8.7 20.6 2.3 8.2 14.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MIP-T3 PF10243.4 EDN99642.1 - 2.4 6.5 65.5 2.9 6.2 45.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 EDN99642.1 - 7.3 6.2 50.5 8.8 6.0 35.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Glyco_hydro_16 PF00722.16 EDN99643.1 - 6.6e-43 146.1 7.4 6.6e-43 146.1 5.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EDN99643.1 - 0.021 14.7 13.3 0.05 13.6 9.3 1.5 1 0 0 1 1 1 0 Chitin recognition protein WAP PF00095.16 EDN99643.1 - 0.48 10.4 8.8 0.25 11.3 4.8 1.5 1 1 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF1180 PF06679.7 EDN99643.1 - 7.3 6.4 9.8 4.8 7.0 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_76 PF03663.9 EDN99644.1 - 6.2e-143 476.6 15.6 7.5e-143 476.3 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 WSC PF01822.14 EDN99646.1 - 9.2e-11 41.5 3.3 2.5e-10 40.1 2.3 1.8 1 0 0 1 1 1 1 WSC domain WSC PF01822.14 EDN99649.1 - 4.2e-10 39.4 12.5 1.2e-09 37.9 8.7 1.8 1 0 0 1 1 1 1 WSC domain KOW PF00467.24 EDN99650.1 - 3.3e-07 29.7 1.3 8.9e-07 28.3 0.9 1.7 1 0 0 1 1 1 1 KOW motif adh_short PF00106.20 EDN99651.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99651.1 - 2.1e-08 34.2 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99651.1 - 6.5e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 KR domain KR PF08659.5 EDN99657.1 - 1.3e-05 24.9 0.0 1.3e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EDN99657.1 - 0.00091 19.1 0.0 0.00092 19.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase NIPSNAP PF07978.8 EDN99658.1 - 0.04 13.8 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 NIPSNAP UvrB PF12344.3 EDN99658.1 - 0.14 11.7 0.4 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B 4HBT PF03061.17 EDN99659.1 - 9.7e-09 35.2 0.1 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MF_alpha_N PF05436.6 EDN99661.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF4625 PF15418.1 EDN99662.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) CLAMP PF14769.1 EDN99662.1 - 0.035 14.2 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Herpes_DNAp_acc PF04929.7 EDN99663.1 - 0.026 13.5 1.8 0.075 11.9 1.7 1.4 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Macoilin PF09726.4 EDN99663.1 - 4.4 5.4 8.3 4.5 5.4 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Aminotran_1_2 PF00155.16 EDN99666.1 - 1.6e-42 145.7 0.0 2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDN99666.1 - 6.9e-07 28.3 0.0 1.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDN99666.1 - 3.8e-05 22.1 0.0 5.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 EDN99666.1 - 8.1e-05 21.3 0.0 0.00012 20.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 EDN99666.1 - 0.00021 20.0 0.4 0.0037 15.9 0.1 2.3 1 1 1 2 2 2 1 Allinase DegT_DnrJ_EryC1 PF01041.12 EDN99666.1 - 0.03 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.19 EDN99667.1 - 7.8e-36 123.2 21.1 1.7e-35 122.0 14.6 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EDN99667.1 - 1.5e-24 86.8 0.0 2.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN99667.1 - 2.8e-09 37.3 0.0 3.9e-07 30.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EDN99667.1 - 4.5e-06 25.9 28.0 4.5e-06 25.9 19.4 1.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EDN99667.1 - 0.00046 19.6 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 EDN99667.1 - 0.012 15.6 1.8 0.012 15.6 1.2 4.2 4 0 0 4 4 3 0 Human growth factor-like EGF AAA_29 PF13555.1 EDN99667.1 - 0.012 15.1 0.1 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN99667.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN99667.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EDN99667.1 - 0.02 14.1 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 EDN99667.1 - 0.03 13.3 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF1212 PF06738.7 EDN99667.1 - 0.036 13.5 4.0 0.12 11.8 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) AAA_17 PF13207.1 EDN99667.1 - 0.049 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN99667.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDN99667.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EDN99667.1 - 0.086 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EDN99667.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EDN99667.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN99667.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EDN99667.1 - 0.22 10.1 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein S4 PF01479.20 EDN99667.1 - 0.23 10.9 1.7 0.46 9.9 0.4 1.9 2 0 0 2 2 2 0 S4 domain TPT PF03151.11 EDN99668.1 - 7.9e-19 67.8 23.9 2.2e-18 66.3 3.9 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDN99668.1 - 4.4e-07 29.9 31.9 8.2e-07 29.1 5.8 3.1 2 2 1 3 3 3 3 EamA-like transporter family DUF2061 PF09834.4 EDN99668.1 - 0.9 9.7 4.5 4.3 7.6 0.2 3.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) DUF788 PF05620.6 EDN99668.1 - 0.91 9.3 5.1 12 5.7 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF788) Vma12 PF11712.3 EDN99668.1 - 2.2 7.9 7.4 2 8.1 0.0 3.2 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SQS_PSY PF00494.14 EDN99669.1 - 9.4e-39 133.2 0.0 3.4e-38 131.4 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Ni_hydr_CYTB PF01292.15 EDN99669.1 - 0.018 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DnaJ-X PF14308.1 EDN99670.1 - 4.8e-72 241.5 2.3 4.8e-72 241.5 1.6 2.6 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDN99670.1 - 4e-25 87.3 0.8 1e-24 85.9 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.12 EDN99671.1 - 3.5e-14 52.3 0.0 9.3e-14 50.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EDN99671.1 - 1.4e-12 47.5 0.0 2.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN99671.1 - 0.00011 21.2 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDN99671.1 - 0.02 13.8 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Macro PF01661.16 EDN99671.1 - 0.06 13.2 0.2 0.21 11.4 0.0 2.0 3 0 0 3 3 3 0 Macro domain 3Beta_HSD PF01073.14 EDN99671.1 - 0.081 11.6 0.1 0.15 10.6 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PIP5K PF01504.13 EDN99674.1 - 3.2e-52 177.1 0.0 7.1e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EDN99674.1 - 3.4e-26 91.9 0.0 5.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EDN99674.1 - 8.1e-10 38.4 6.2 8.1e-10 38.4 4.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger Mig-14 PF07395.6 EDN99674.1 - 0.1 11.6 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Mig-14 NGP1NT PF08153.7 EDN99675.1 - 6.8e-49 165.1 0.1 1.2e-48 164.3 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EDN99675.1 - 1.8e-18 66.5 0.0 3.4e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN99675.1 - 0.00029 20.1 0.1 0.0015 17.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDN99675.1 - 0.00075 18.9 0.0 0.13 11.7 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EDN99675.1 - 0.0019 17.4 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EDN99675.1 - 0.0039 16.3 0.0 0.0084 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN99675.1 - 0.02 14.7 6.3 0.37 10.5 0.0 3.7 3 1 1 4 4 4 0 Dynamin family AAA_28 PF13521.1 EDN99675.1 - 0.14 12.0 1.0 14 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain DSBA PF01323.15 EDN99676.1 - 0.097 12.2 1.9 0.15 11.6 1.3 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain FAM60A PF15396.1 EDN99676.1 - 1.3 8.7 4.6 2.1 8.0 3.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TMEM154 PF15102.1 EDN99677.1 - 0.0027 17.4 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF2217 PF10265.4 EDN99677.1 - 0.013 14.2 1.4 4.4 5.9 1.6 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Plasmodium_Vir PF05795.6 EDN99677.1 - 0.1 11.8 0.7 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF912 PF06024.7 EDN99677.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Iso_dh PF00180.15 EDN99679.1 - 3e-98 329.0 0.0 5.8e-98 328.0 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Clr5 PF14420.1 EDN99680.1 - 1.1e-11 44.4 1.8 1.5e-11 44.0 1.2 1.2 1 0 0 1 1 1 1 Clr5 domain Clr5 PF14420.1 EDN99683.1 - 6.8e-17 61.1 0.5 1.8e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 Clr5 domain Retrotrans_gag PF03732.12 EDN99683.1 - 0.0066 16.4 0.1 1.6 8.8 0.0 3.6 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4064 PF13273.1 EDN99684.1 - 0.08 13.0 0.1 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2650 PF10853.3 EDN99684.1 - 2.1 7.8 6.6 5.7 6.4 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Metallothio_Cad PF07846.6 EDN99684.1 - 2.3 8.2 11.0 0.17 11.7 3.2 2.5 2 0 0 2 2 2 0 Metallothionein family MFS_1 PF07690.11 EDN99685.1 - 1.2e-08 34.1 1.9 1.3e-08 34.0 1.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SUR7 PF06687.7 EDN99686.1 - 5.5e-33 114.3 13.6 7.7e-33 113.8 9.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Shisa PF13908.1 EDN99686.1 - 0.062 13.4 4.1 4.3 7.4 0.4 2.2 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Metallophos PF00149.23 EDN99689.1 - 2e-40 138.3 0.2 2.6e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 EDN99689.1 - 0.34 10.2 3.3 0.69 9.2 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Nuc_sug_transp PF04142.10 EDN99690.1 - 1.9e-16 59.9 5.5 1.9e-16 59.9 3.8 1.9 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EDN99690.1 - 0.0051 16.4 0.5 0.0051 16.4 0.4 3.4 3 2 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EDN99690.1 - 0.0076 16.2 1.8 0.0076 16.2 1.3 3.5 2 1 1 3 3 3 1 EamA-like transporter family DUF2569 PF10754.4 EDN99690.1 - 0.099 12.8 6.3 1.2 9.3 4.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) AA_permease_2 PF13520.1 EDN99691.1 - 1.1e-42 146.1 52.2 1.4e-42 145.7 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN99691.1 - 4.7e-19 68.0 44.4 6.6e-19 67.6 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.1 EDN99691.1 - 7.7 6.5 21.3 3.1 7.8 0.0 5.2 4 2 1 5 5 5 0 Protein of unknown function (DUF4231) DDE_Tnp_1_6 PF13751.1 EDN99692.1 - 0.63 10.0 4.8 1 9.3 3.3 1.3 1 0 0 1 1 1 0 Transposase DDE domain bZIP_1 PF00170.16 EDN99694.1 - 2.6e-09 36.8 15.7 4.5e-09 36.1 10.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDN99694.1 - 0.0035 17.5 9.6 0.0053 17.0 6.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EDN99694.1 - 0.0077 16.0 13.0 0.015 15.1 9.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Phage_lysis PF03245.8 EDN99694.1 - 0.017 15.1 4.1 0.027 14.4 2.8 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein GAS PF13851.1 EDN99694.1 - 0.028 13.6 7.4 0.039 13.1 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EDN99694.1 - 0.075 13.3 3.0 0.073 13.4 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 EDN99694.1 - 0.11 12.3 10.4 0.17 11.7 7.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DDHD PF02862.12 EDN99694.1 - 0.19 11.4 3.0 0.25 11.1 2.1 1.1 1 0 0 1 1 1 0 DDHD domain APG6 PF04111.7 EDN99694.1 - 0.23 10.4 3.8 0.28 10.1 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Glutaredoxin2_C PF04399.8 EDN99694.1 - 0.72 9.4 3.1 1.1 8.8 2.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Phage_min_cap2 PF06152.6 EDN99694.1 - 0.99 8.3 4.3 1.4 7.8 3.0 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 DivIC PF04977.10 EDN99694.1 - 1.7 8.1 6.4 3.5 7.1 4.5 1.6 1 1 0 1 1 1 0 Septum formation initiator Glyco_hydro_28 PF00295.12 EDN99695.1 - 1.1e-17 63.9 9.2 7.8e-08 31.6 0.1 3.1 1 1 2 3 3 3 3 Glycosyl hydrolases family 28 CDP-OH_P_transf PF01066.16 EDN99696.1 - 2.4e-16 59.8 1.0 2.4e-16 59.8 0.7 2.4 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 EDN99697.1 - 5e-113 378.2 0.4 6.5e-113 377.8 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EDN99697.1 - 3.5e-59 198.9 5.4 6.9e-59 198.0 3.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EDN99697.1 - 4e-15 55.8 0.3 4e-05 23.8 0.0 5.5 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EDN99697.1 - 0.0018 18.5 0.1 3.6 8.3 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EDN99697.1 - 0.003 16.9 2.9 0.011 15.0 0.1 2.8 3 0 0 3 3 3 1 CLASP N terminal DUF3730 PF12530.3 EDN99697.1 - 0.0097 15.8 1.7 0.14 12.0 0.3 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.17 EDN99697.1 - 0.029 14.4 6.6 1 9.6 0.2 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EDN99697.1 - 1.1 9.8 6.0 0.62 10.6 0.6 3.1 3 0 0 3 3 3 0 HEAT-like repeat Hydrolase_6 PF13344.1 EDN99698.1 - 3.5e-27 94.2 0.0 8.8e-27 92.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN99698.1 - 2.4e-17 62.3 0.1 4.9e-16 58.1 0.0 2.8 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EDN99698.1 - 4.6e-07 30.2 0.1 0.051 13.7 0.1 4.1 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN99698.1 - 1.9e-05 25.1 0.0 0.64 10.3 0.0 3.5 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase RNR_inhib PF08591.5 EDN99699.1 - 3.1e-29 101.7 0.2 5e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor SIP1 PF04938.7 EDN99700.1 - 4.1e-05 23.0 0.0 0.0023 17.3 0.0 2.9 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) F-box-like PF12937.2 EDN99701.1 - 6.3e-09 35.4 1.7 1.4e-08 34.3 1.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EDN99701.1 - 0.011 15.3 0.1 0.22 11.1 0.1 3.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EDN99701.1 - 0.027 14.1 0.3 0.087 12.5 0.2 1.8 1 0 0 1 1 1 0 F-box domain alpha-hel2 PF14456.1 EDN99701.1 - 0.046 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 TelA PF05816.6 EDN99704.1 - 0.021 13.5 0.5 0.026 13.2 0.3 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF2574 PF10836.3 EDN99704.1 - 0.091 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Rhabdo_glycop PF00974.13 EDN99705.1 - 0.043 12.0 0.0 0.044 12.0 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein FMO-like PF00743.14 EDN99706.1 - 0.4 8.8 0.0 0.6 8.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Asp PF00026.18 EDN99712.1 - 2.3e-54 184.8 1.8 6.2e-36 124.2 2.2 2.4 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN99712.1 - 6.4e-10 39.2 0.2 2.6e-09 37.2 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDN99712.1 - 0.00023 21.5 2.9 0.075 13.5 0.6 3.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EDN99712.1 - 0.1 12.1 0.0 0.35 10.4 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Epimerase PF01370.16 EDN99713.1 - 1.5e-07 31.0 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hemocyanin_N PF03722.9 EDN99713.1 - 0.029 14.5 0.1 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain PPR_2 PF13041.1 EDN99713.1 - 0.049 13.6 0.1 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family NAD_binding_10 PF13460.1 EDN99713.1 - 0.051 13.5 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding SCO1-SenC PF02630.9 EDN99714.1 - 1.3e-57 194.2 0.0 1.7e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EDN99714.1 - 0.00032 20.3 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EDN99714.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like GRAM PF02893.15 EDN99714.1 - 0.046 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Peptidase_M32 PF02074.10 EDN99715.1 - 1.1 7.7 6.1 1.7 7.2 4.3 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase GRAM PF02893.15 EDN99718.1 - 0.0037 16.7 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DUF972 PF06156.8 EDN99719.1 - 0.059 13.7 5.6 0.32 11.3 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EDN99719.1 - 0.09 12.2 8.5 0.89 9.0 2.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 EDN99719.1 - 0.13 12.5 10.6 1.3 9.3 0.2 2.9 2 0 0 2 2 2 0 Striatin family bZIP_1 PF00170.16 EDN99719.1 - 0.25 11.3 8.7 4.2 7.4 0.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 EDN99719.1 - 0.79 9.4 8.5 0.18 11.5 0.2 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIVA PF05103.8 EDN99719.1 - 1 9.4 4.9 4.9 7.2 0.4 2.5 2 0 0 2 2 2 0 DivIVA protein ADIP PF11559.3 EDN99719.1 - 2.2 8.1 10.3 1.7 8.5 1.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.4 EDN99719.1 - 6.4 6.8 7.8 2.7 8.0 1.3 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Fumble PF03630.9 EDN99720.1 - 3.3e-129 430.6 0.1 2.7e-128 427.6 0.0 1.9 1 1 0 1 1 1 1 Fumble CFEM PF05730.6 EDN99722.1 - 2e-10 40.3 10.3 3.3e-10 39.6 7.1 1.4 1 0 0 1 1 1 1 CFEM domain Yae1_N PF09811.4 EDN99723.1 - 1.2e-13 50.3 3.0 2.3e-13 49.4 2.1 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Na_H_antiport_1 PF06965.7 EDN99723.1 - 0.098 11.4 0.1 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Glyoxal_oxid_N PF07250.6 EDN99724.1 - 8.1e-42 142.9 0.0 2.8e-40 137.9 0.0 3.1 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EDN99724.1 - 4.1e-22 78.1 0.2 9.4e-22 76.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EDN99724.1 - 5.4e-17 61.4 82.8 1.1e-06 28.5 17.0 3.6 3 0 0 3 3 3 3 Chitin recognition protein Annexin PF00191.15 EDN99725.1 - 1e-11 44.5 0.4 0.00028 20.7 0.0 3.4 3 0 0 3 3 3 3 Annexin MFS_1 PF07690.11 EDN99727.1 - 1.9e-33 115.6 21.6 1.9e-33 115.6 15.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EDN99728.1 - 9.1e-20 71.3 0.1 1.9e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN99728.1 - 3.8e-11 43.1 0.0 9.4e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WSC PF01822.14 EDN99729.1 - 1.2e-09 37.9 12.1 1.2e-09 37.9 8.4 2.4 3 0 0 3 3 3 1 WSC domain Mid2 PF04478.7 EDN99729.1 - 0.0018 17.6 2.0 0.0018 17.6 1.4 2.1 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Rax2 PF12768.2 EDN99729.1 - 0.0087 15.3 0.5 0.021 14.0 0.4 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity FixQ PF05545.6 EDN99729.1 - 0.019 14.5 0.8 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Adeno_E3_CR2 PF02439.10 EDN99729.1 - 0.1 12.1 0.6 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF566 PF04484.7 EDN99729.1 - 0.11 11.9 2.8 0.16 11.4 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) EBA-175_VI PF11556.3 EDN99729.1 - 0.11 12.5 1.8 0.25 11.4 1.3 1.5 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 DUF4064 PF13273.1 EDN99729.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Hamartin PF04388.7 EDN99729.1 - 1.7 7.2 6.7 2.3 6.8 4.6 1.3 1 0 0 1 1 1 0 Hamartin protein HET PF06985.6 EDN99732.1 - 3.4e-22 79.1 0.1 6.3e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.21 EDN99734.1 - 7.1e-13 48.2 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ArfGap PF01412.13 EDN99735.1 - 7.1e-33 112.8 0.0 1.4e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Cytochrom_C_2 PF01322.15 EDN99735.1 - 0.0044 17.5 0.9 0.011 16.2 0.6 1.7 1 0 0 1 1 1 1 Cytochrome C' RRM_1 PF00076.17 EDN99736.1 - 2.5e-28 97.4 0.0 9.6e-13 47.5 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN99736.1 - 2.1e-21 75.6 0.0 4.8e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN99736.1 - 4.8e-11 42.3 0.0 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EDN99736.1 - 0.0042 15.6 2.1 0.0052 15.3 1.5 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Limkain-b1 PF11608.3 EDN99736.1 - 0.015 15.0 0.8 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 DbpA PF03880.10 EDN99736.1 - 0.13 11.9 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain DUF2201_N PF13203.1 EDN99736.1 - 1.5 7.8 6.0 3.3 6.7 4.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Flavodoxin_1 PF00258.20 EDN99738.1 - 2.2e-31 108.7 0.0 4.2e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EDN99738.1 - 3.4e-27 95.3 0.0 8.1e-25 87.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EDN99738.1 - 1.2e-11 45.1 0.0 2.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EDN99738.1 - 0.00059 19.8 0.0 0.0023 17.9 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 EDN99738.1 - 0.0012 18.2 0.0 0.0035 16.7 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain SBP_bac_1 PF01547.20 EDN99738.1 - 0.091 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Raffinose_syn PF05691.7 EDN99739.1 - 1.3e-41 141.9 0.5 4.6e-39 133.6 0.4 2.9 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 F-box PF00646.28 EDN99740.1 - 0.00059 19.4 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN99740.1 - 0.0012 18.5 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EDN99740.1 - 0.086 12.5 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 F-box-like domain CAF1-p150_N PF15557.1 EDN99743.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA HET PF06985.6 EDN99744.1 - 1.5e-30 106.1 2.3 2.5e-30 105.4 1.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SMC_Nse1 PF07574.8 EDN99745.1 - 7e-33 113.9 0.0 9.6e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EDN99745.1 - 3.7e-11 42.8 8.7 5.8e-11 42.2 6.1 1.3 1 0 0 1 1 1 1 RING-like domain DUF2161 PF09929.4 EDN99745.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Mrr_N PF14338.1 EDN99745.1 - 0.042 13.9 0.1 2.9 8.0 0.0 2.8 2 1 0 2 2 2 0 Mrr N-terminal domain FYDLN_acid PF09538.5 EDN99745.1 - 1.2 9.7 8.2 0.21 12.2 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF427 PF04248.7 EDN99746.1 - 6e-21 73.9 0.3 8.5e-21 73.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) WRKY PF03106.10 EDN99747.1 - 0.049 13.4 0.4 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain Pyridoxal_deC PF00282.14 EDN99749.1 - 5.1e-119 397.0 0.0 6.7e-119 396.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EDN99749.1 - 0.0058 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_1b PF00579.20 EDN99750.1 - 2.6e-76 256.5 0.0 3.6e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_34 PF13601.1 EDN99750.1 - 0.13 12.3 0.6 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain Raffinose_syn PF05691.7 EDN99751.1 - 2.6e-52 177.4 4.3 8.4e-47 159.1 1.9 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EDN99751.1 - 0.0028 16.4 0.2 0.0047 15.6 0.1 1.2 1 0 0 1 1 1 1 Melibiase ocr PF08684.5 EDN99751.1 - 0.034 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 DNA mimic ocr Abhydrolase_2 PF02230.11 EDN99752.1 - 2.6e-30 105.4 0.0 4.3e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EDN99752.1 - 2.5e-05 23.8 0.0 9.2e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDN99752.1 - 0.00054 19.7 0.0 0.0009 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN99752.1 - 0.00097 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDN99752.1 - 0.0095 15.8 0.1 0.086 12.7 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Aldedh PF00171.17 EDN99753.1 - 1.2e-163 544.7 0.1 1.4e-163 544.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_8 PF13855.1 EDN99758.1 - 0.0011 18.7 5.0 0.45 10.3 0.2 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 EDN99758.1 - 0.18 12.1 7.2 1.7 9.1 0.1 5.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 EDN99758.1 - 0.61 10.3 6.7 4 7.7 0.3 4.7 5 2 1 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.28 EDN99758.1 - 0.88 9.8 5.6 82 3.8 0.1 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 EDN99758.1 - 1.6 8.4 7.3 1.8 8.2 0.7 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3168 PF11367.3 EDN99759.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Glyco_hydro_43 PF04616.9 EDN99760.1 - 9.2e-19 67.5 1.6 1.7e-18 66.7 0.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 SLAC1 PF03595.12 EDN99761.1 - 4.5e-72 242.4 47.5 5.1e-72 242.2 32.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DPM3 PF08285.6 EDN99761.1 - 3.1 7.7 12.0 0.34 10.7 1.7 3.1 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) T2SS-T3SS_pil_N PF13629.1 EDN99762.1 - 0.043 13.3 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Pilus formation protein N terminal region DUF1315 PF07023.7 EDN99764.1 - 0.22 11.4 2.5 0.15 11.9 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1315) MFS_1 PF07690.11 EDN99765.1 - 3e-25 88.6 28.4 1.1e-24 86.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_nucleoca PF00937.13 EDN99765.1 - 0.79 8.6 6.4 1.2 7.9 4.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PsbY PF06298.6 EDN99766.1 - 0.038 13.4 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Glyco_transf_17 PF04724.8 EDN99767.1 - 1.6e-38 132.6 0.1 2.2e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Ank PF00023.25 EDN99770.1 - 0.0023 17.6 0.1 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EDN99770.1 - 0.065 13.5 0.0 7.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat COX6B PF02297.12 EDN99771.1 - 3.3e-27 94.3 5.2 3.9e-27 94.0 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EDN99771.1 - 0.008 16.2 0.2 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 Prolamin-like Pet191_N PF10203.4 EDN99771.1 - 0.072 13.1 1.6 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0075 PF03702.9 EDN99772.1 - 3.6e-48 164.3 0.0 4.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF3592 PF12158.3 EDN99775.1 - 0.42 10.3 0.0 0.42 10.3 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) UNC-50 PF05216.8 EDN99775.1 - 0.86 8.7 8.7 2.7 7.1 6.2 1.7 1 1 0 1 1 1 0 UNC-50 family DUF4293 PF14126.1 EDN99775.1 - 6 6.7 8.6 1.2 9.0 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Diphthamide_syn PF01866.12 EDN99776.1 - 7.7e-50 169.8 0.0 1.5e-49 168.9 0.0 1.4 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Clr5 PF14420.1 EDN99777.1 - 2.2e-17 62.6 0.2 4e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 Clr5 domain HTH_21 PF13276.1 EDN99777.1 - 0.012 15.5 3.7 0.28 11.2 2.7 2.6 2 1 0 2 2 2 0 HTH-like domain ETS_PEA3_N PF04621.8 EDN99778.1 - 0.1 11.7 7.5 0.1 11.8 5.2 1.0 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Amidase PF01425.16 EDN99779.1 - 4.4e-86 289.4 0.0 3.7e-48 164.4 0.3 2.0 2 0 0 2 2 2 2 Amidase FixQ PF05545.6 EDN99781.1 - 0.0021 17.6 0.7 0.0033 17.0 0.5 1.3 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Herpes_DNAp_acc PF04929.7 EDN99784.1 - 3.1 6.6 4.6 3.1 6.6 3.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor THEG PF14912.1 EDN99785.1 - 0.12 12.9 0.5 0.2 12.2 0.3 1.5 1 1 0 1 1 1 0 Testicular haploid expressed repeat Pkinase PF00069.20 EDN99786.1 - 1.7e-39 135.5 0.0 6.4e-39 133.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99786.1 - 7.6e-30 103.8 0.0 1.2e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN99786.1 - 0.00031 19.8 0.0 0.00062 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN99786.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EDN99789.1 - 5.9e-29 98.8 18.3 1.3e-09 37.5 0.0 10.8 10 0 0 10 10 10 8 WD domain, G-beta repeat K-cyclin_vir_C PF09080.5 EDN99789.1 - 0.091 12.9 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 K cyclin, C terminal PIG-S PF10510.4 EDN99790.1 - 1.9e-79 267.6 0.0 2.5e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.23 EDN99791.1 - 3.2e-63 213.5 0.0 4.1e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN99791.1 - 4.1e-12 46.8 1.4 4.6e-11 43.4 0.1 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain PHY PF00360.15 EDN99792.1 - 1.9e-25 89.1 0.0 4.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EDN99792.1 - 2.4e-17 62.6 0.1 4.5e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN99792.1 - 3e-15 56.1 0.0 9.6e-15 54.5 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EDN99792.1 - 8.8e-15 55.1 0.0 2.6e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.6 EDN99792.1 - 3.8e-08 33.7 0.0 1.1e-07 32.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 EDN99792.1 - 1.1e-07 31.6 2.1 3.8e-07 30.0 0.3 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Gln-synt_C PF00120.19 EDN99793.1 - 1.7e-53 181.4 0.0 2.7e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EDN99793.1 - 7e-28 97.9 0.0 1.5e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_S8 PF00410.14 EDN99794.1 - 1e-23 83.5 0.0 1.3e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Cyt-b5 PF00173.23 EDN99797.1 - 3.1e-15 55.7 0.0 5.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 EDN99798.1 - 7.7e-07 29.1 0.1 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Glyco_transf_7C PF02709.9 EDN99798.1 - 0.019 14.4 0.2 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Polysacc_synt_4 PF04669.8 EDN99800.1 - 3.3e-26 91.8 1.2 1.8e-25 89.4 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis FAD_binding_3 PF01494.14 EDN99805.1 - 6.9e-18 64.8 1.4 2.3e-13 49.9 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain ADC PF06314.6 EDN99805.1 - 1.7e-10 40.6 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.19 EDN99805.1 - 0.00043 19.2 0.3 0.00068 18.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN99805.1 - 0.00071 18.5 1.8 0.013 14.4 1.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN99805.1 - 0.0043 16.9 0.1 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN99805.1 - 0.011 15.7 1.1 0.023 14.7 0.8 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EDN99805.1 - 0.016 14.7 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EDN99805.1 - 0.16 12.3 0.9 0.42 11.0 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN99805.1 - 0.26 9.8 2.2 1.3 7.5 0.6 2.1 1 1 0 2 2 2 0 Tryptophan halogenase Rick_17kDa_Anti PF05433.10 EDN99806.1 - 0.045 13.4 8.4 0.093 12.4 5.8 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain TraT PF05818.7 EDN99806.1 - 0.054 12.9 0.1 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF4514 PF14986.1 EDN99806.1 - 0.085 12.6 2.1 2 8.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4514) SAM_PNT PF02198.11 EDN99811.1 - 0.12 12.1 0.6 0.22 11.3 0.4 1.4 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain GPI2 PF06432.6 EDN99812.1 - 1.9e-124 414.6 4.4 2.2e-124 414.3 3.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase zf-MYND PF01753.13 EDN99813.1 - 2.4e-10 40.0 7.2 3.8e-10 39.4 5.0 1.3 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EDN99814.1 - 4.9e-08 32.6 7.9 8.2e-08 31.9 5.5 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EDN99814.1 - 0.25 11.0 6.9 0.47 10.1 4.8 1.5 1 0 0 1 1 1 0 HIT zinc finger COX7C PF02935.11 EDN99816.1 - 1.3 8.8 4.7 1.3 8.8 2.3 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc OPT PF03169.10 EDN99818.1 - 3.2e-161 537.8 49.8 3.7e-161 537.6 34.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.13 EDN99820.1 - 6.9e-14 51.3 0.3 9.8e-14 50.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN99820.1 - 2.5e-07 30.5 9.0 5.1e-07 29.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_U59 PF04529.7 EDN99820.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus U59 protein Med9 PF07544.8 EDN99820.1 - 0.036 13.8 0.2 0.082 12.6 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_76 PF03663.9 EDN99824.1 - 8.3e-153 509.1 20.5 1.1e-152 508.7 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Galanin PF01296.13 EDN99824.1 - 0.16 11.8 0.8 0.32 10.8 0.6 1.4 1 0 0 1 1 1 0 Galanin Glyco_hydro_88 PF07470.8 EDN99824.1 - 0.16 10.9 10.8 0.29 10.1 0.8 3.0 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 AMP-binding PF00501.23 EDN99826.1 - 1.1e-29 103.1 0.0 7.3e-29 100.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN99827.1 - 7.7e-29 100.3 0.0 1e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EDN99827.1 - 7.5e-10 38.6 0.0 9.8e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN99827.1 - 0.0062 15.2 0.0 0.015 14.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EDN99827.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase APH PF01636.18 EDN99828.1 - 2e-14 53.8 0.0 3.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN99828.1 - 5.7e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EDN99828.1 - 0.0026 16.9 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN99828.1 - 0.0035 16.4 0.0 0.042 12.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Prothymosin PF03247.9 EDN99828.1 - 0.02 15.0 23.7 0.032 14.3 16.4 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Mit_KHE1 PF10173.4 EDN99828.1 - 0.12 12.1 0.6 2 8.2 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related CDC45 PF02724.9 EDN99828.1 - 0.62 8.0 9.2 0.82 7.6 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EDN99828.1 - 0.78 8.1 14.3 0.99 7.8 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EDN99828.1 - 0.86 7.4 15.8 1.2 6.9 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EDN99828.1 - 1 8.3 14.3 1.4 7.9 9.9 1.2 1 0 0 1 1 1 0 BUD22 Upf2 PF04050.9 EDN99828.1 - 2.6 7.7 19.2 4.2 7.1 13.3 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DDE_1 PF03184.14 EDN99830.1 - 2.2e-32 111.9 0.2 4.2e-32 111.0 0.1 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN99830.1 - 1e-10 41.0 0.7 2.5e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN99830.1 - 6.7e-07 29.0 1.1 2.6e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN99830.1 - 1.5e-05 24.7 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4626 PF15422.1 EDN99832.1 - 0.074 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) Phage_Coat_Gp8 PF05371.7 EDN99835.1 - 0.15 11.6 2.5 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Acyl_transf_3 PF01757.17 EDN99835.1 - 3.2 6.4 33.1 7.2 5.3 23.0 1.6 1 1 0 1 1 1 0 Acyltransferase family Glyco_tranf_2_3 PF13641.1 EDN99836.1 - 3.1e-28 99.1 0.0 1.2e-27 97.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDN99836.1 - 2.4e-21 76.3 6.7 2.4e-21 76.3 4.6 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EDN99836.1 - 1.3e-08 34.3 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN99836.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Acyl_transf_3 PF01757.17 EDN99837.1 - 6.1e-06 25.2 17.8 1.1e-05 24.4 12.4 1.4 1 0 0 1 1 1 1 Acyltransferase family ABC2_membrane_2 PF12679.2 EDN99837.1 - 0.068 12.0 3.3 0.11 11.3 2.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ADH_zinc_N PF00107.21 EDN99838.1 - 6.9e-08 32.1 0.2 1.5e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN99838.1 - 2.9e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EDN99839.1 - 1.4e-05 24.9 10.9 1.4e-05 24.9 7.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.26 EDN99840.1 - 1.6e-09 37.7 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.21 EDN99843.1 - 4.2e-14 52.2 0.4 8.8e-13 47.9 0.3 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EDN99843.1 - 8.9e-06 25.7 0.7 1.3e-05 25.1 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDN99843.1 - 1.2e-05 25.4 0.8 1.9e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EDN99843.1 - 6.9e-05 22.5 0.0 0.0035 17.0 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDN99843.1 - 0.00022 22.1 0.1 0.00045 21.1 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EDN99843.1 - 0.00028 20.3 0.1 0.00041 19.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EDN99843.1 - 0.0024 16.8 0.2 0.0097 14.8 0.1 1.8 1 1 1 2 2 2 1 RmlD substrate binding domain PGM_PMM_II PF02879.11 EDN99843.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TusA PF01206.12 EDN99843.1 - 0.015 14.8 0.0 0.69 9.5 0.0 2.7 3 0 0 3 3 3 0 Sulfurtransferase TusA 2-Hacid_dh_C PF02826.14 EDN99843.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EDN99843.1 - 0.056 13.3 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EDN99843.1 - 0.093 11.9 0.2 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 EDN99843.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 KR domain Med13_C PF06333.7 EDN99844.1 - 5.6 5.3 7.1 3 6.2 3.8 1.4 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal Arylesterase PF01731.15 EDN99845.1 - 0.051 13.5 0.0 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 Arylesterase DUF500 PF04366.7 EDN99847.1 - 1.2e-42 144.3 0.1 2e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Actino_peptide PF14408.1 EDN99848.1 - 0.072 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes 4HBT_3 PF13622.1 EDN99849.1 - 0.23 11.1 4.9 0.31 10.7 3.4 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily PAT1 PF09770.4 EDN99849.1 - 1.2 7.2 7.3 1.6 6.8 5.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3340 PF11818.3 EDN99849.1 - 3.5 7.5 12.7 3 7.8 7.4 1.8 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF605 PF04652.11 EDN99849.1 - 4.4 6.6 22.7 5.5 6.2 15.7 1.2 1 0 0 1 1 1 0 Vta1 like Lipase_GDSL PF00657.17 EDN99850.1 - 1.8e-08 34.5 0.3 2.4e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-met2 PF12907.2 EDN99855.1 - 0.054 13.4 0.7 0.086 12.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-binding MFS_1 PF07690.11 EDN99857.1 - 1.2e-27 96.5 32.2 1.1e-22 80.2 10.6 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.16 EDN99857.1 - 0.022 14.2 0.1 0.022 14.2 0.1 3.2 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus Ferrochelatase PF00762.14 EDN99858.1 - 8.7e-88 294.3 0.0 1.1e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EDN99859.1 - 9.4e-41 139.4 0.0 2.9e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDN99859.1 - 5.8e-33 114.2 0.0 7.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EDN99859.1 - 1.6e-12 47.8 0.1 1.6e-12 47.8 0.1 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EDN99859.1 - 1.1e-06 28.0 0.2 2.5e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EDN99859.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 EDN99859.1 - 0.048 13.3 0.0 0.27 10.9 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain DDE_1 PF03184.14 EDN99863.1 - 0.013 14.6 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Tho2 PF11262.3 EDN99865.1 - 4.1e-85 285.4 0.0 5.7e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EDN99865.1 - 9.2e-26 89.4 0.0 1.9e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 EDN99866.1 - 1.6e-46 158.6 0.0 3.8e-46 157.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN99866.1 - 6.1e-16 58.9 0.3 5.8e-15 55.7 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN99866.1 - 0.00084 19.1 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EDN99866.1 - 0.0023 17.8 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF2424 PF10340.4 EDN99866.1 - 0.021 13.5 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) ERG4_ERG24 PF01222.12 EDN99867.1 - 7.9e-96 321.2 11.4 9.5e-96 320.9 7.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EDN99867.1 - 2.8e-05 23.5 0.3 9.6e-05 21.7 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) VIT1 PF01988.14 EDN99867.1 - 0.098 12.1 0.6 3.3 7.1 0.1 2.2 2 0 0 2 2 2 0 VIT family Sugar_tr PF00083.19 EDN99869.1 - 8.5e-48 163.0 16.3 1.2e-47 162.5 11.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN99869.1 - 3.2e-17 62.2 25.5 4.8e-17 61.7 17.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_90 PF05686.7 EDN99870.1 - 5.3e-14 51.7 0.0 1.8e-09 36.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EDN99870.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 ACPS PF01648.15 EDN99873.1 - 3.7e-06 26.7 0.0 0.00013 21.7 0.0 3.0 2 2 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Zn_clus PF00172.13 EDN99875.1 - 0.0011 18.8 4.3 0.0027 17.5 3.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EDN99876.1 - 5e-30 104.5 0.9 7.4e-30 104.0 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN99876.1 - 1.3e-20 72.6 0.5 2.1e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN99876.1 - 1.8e-20 73.6 0.0 5e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN99876.1 - 0.00014 22.1 0.1 0.00024 21.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ICL PF00463.16 EDN99876.1 - 0.08 11.1 0.1 0.96 7.5 0.0 2.0 2 0 0 2 2 2 0 Isocitrate lyase family Sugar_tr PF00083.19 EDN99879.1 - 1.3e-73 248.1 35.0 1.6e-73 247.8 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN99879.1 - 3.3e-31 108.2 42.5 1.3e-26 93.1 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1422 PF07226.6 EDN99879.1 - 0.72 9.5 11.0 1.7 8.4 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1422) adh_short PF00106.20 EDN99880.1 - 1.5e-30 106.3 0.5 1.9e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99880.1 - 5.5e-28 98.3 0.1 6.5e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99880.1 - 3.6e-11 43.0 0.2 5.3e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN99880.1 - 0.00017 21.1 0.1 0.00028 20.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EDN99880.1 - 0.0089 15.6 0.6 0.015 14.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBP_bac_3 PF00497.15 EDN99880.1 - 0.0089 15.2 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 3Beta_HSD PF01073.14 EDN99880.1 - 0.024 13.3 0.8 0.037 12.7 0.5 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNA_pol_Rpb1_4 PF05000.12 EDN99880.1 - 0.033 13.9 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 adh_short PF00106.20 EDN99883.1 - 2.4e-28 99.1 0.3 3.6e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99883.1 - 4.5e-24 85.5 0.9 1.1e-22 80.9 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99883.1 - 1.3e-15 57.5 0.1 1.9e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN99883.1 - 9.2e-05 21.9 0.8 0.00038 19.9 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EDN99883.1 - 0.025 13.7 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HET PF06985.6 EDN99884.1 - 1.2e-18 67.6 2.4 2.4e-18 66.6 0.4 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Response_reg PF00072.19 EDN99884.1 - 0.0039 17.1 0.1 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HET PF06985.6 EDN99886.1 - 2.9e-33 114.9 0.3 4.7e-33 114.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_GP20 PF06810.6 EDN99888.1 - 0.0007 19.0 1.0 0.0007 19.0 0.7 2.4 2 1 1 3 3 3 1 Phage minor structural protein GP20 IncA PF04156.9 EDN99888.1 - 0.0014 18.2 1.3 0.0026 17.3 0.9 1.4 1 0 0 1 1 1 1 IncA protein DUF3829 PF12889.2 EDN99888.1 - 0.0032 16.7 0.4 0.0056 15.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Med9 PF07544.8 EDN99888.1 - 0.045 13.4 2.7 0.7 9.6 0.1 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4549 PF15082.1 EDN99888.1 - 0.095 12.3 0.5 0.21 11.2 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) BLOC1_2 PF10046.4 EDN99888.1 - 0.11 12.6 2.4 0.86 9.7 0.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Geminin PF07412.7 EDN99888.1 - 0.38 10.3 9.9 1.9 8.0 0.5 3.4 3 1 1 4 4 4 0 Geminin DUF4200 PF13863.1 EDN99888.1 - 0.92 9.4 0.0 0.92 9.4 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EDN99888.1 - 1.1 8.8 3.5 2 7.9 1.1 2.3 2 0 0 2 2 2 0 Septum formation initiator HAP1_N PF04849.8 EDN99890.1 - 0.00024 20.1 6.0 0.00024 20.1 4.2 1.4 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Fez1 PF06818.10 EDN99890.1 - 0.011 15.8 4.4 0.011 15.8 3.0 2.1 1 1 2 3 3 3 0 Fez1 DUF904 PF06005.7 EDN99890.1 - 0.014 15.6 9.7 0.34 11.2 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Leu_zip PF15294.1 EDN99890.1 - 0.015 14.4 3.6 0.015 14.4 2.5 2.8 2 1 0 3 3 3 0 Leucine zipper PEP-utilisers_N PF05524.8 EDN99890.1 - 0.022 14.5 0.9 0.062 13.0 0.7 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Thioredoxin PF00085.15 EDN99890.1 - 0.088 12.4 0.1 0.8 9.4 0.0 2.4 3 0 0 3 3 2 0 Thioredoxin CENP-Q PF13094.1 EDN99890.1 - 0.13 12.3 11.6 1.5 8.7 2.5 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_BLRF2 PF05812.7 EDN99890.1 - 0.25 11.1 7.4 0.33 10.7 0.3 3.0 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein IFP_35_N PF07334.8 EDN99890.1 - 0.28 11.1 0.2 0.28 11.1 0.1 3.6 3 2 1 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Jnk-SapK_ap_N PF09744.4 EDN99890.1 - 0.35 10.8 9.3 0.73 9.8 0.3 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.1 EDN99890.1 - 0.39 10.6 10.5 0.4 10.6 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF465 PF04325.8 EDN99890.1 - 0.5 10.1 4.1 6.7 6.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF465) ADIP PF11559.3 EDN99890.1 - 0.6 9.9 13.1 0.72 9.7 1.1 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 EDN99890.1 - 1.1 9.2 10.5 0.18 11.7 1.4 2.8 3 1 0 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.6 EDN99890.1 - 2 8.3 9.5 0.53 10.2 0.3 3.2 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 EDN99890.1 - 2.7 7.7 11.0 4.1 7.1 0.8 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.10 EDN99890.1 - 3.3 7.6 13.5 0.07 12.9 2.6 2.9 3 1 0 3 3 3 0 Basic region leucine zipper DivIC PF04977.10 EDN99890.1 - 8.4 5.9 6.7 1.9 8.0 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator LRR_4 PF12799.2 EDN99893.1 - 4e-10 39.0 8.4 5.6e-07 29.0 0.4 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN99893.1 - 9.3e-07 28.5 5.2 1.4e-06 27.9 2.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EDN99893.1 - 0.00015 21.3 5.0 1.1 9.5 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EDN99893.1 - 0.042 14.0 2.8 20 5.9 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat DUF4428 PF14471.1 EDN99894.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF4458 PF14660.1 EDN99897.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) DUF2087 PF09860.4 EDN99898.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Fungal_trans PF04082.13 EDN99900.1 - 3.2e-27 95.0 0.2 7.1e-27 93.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain pKID PF02173.12 EDN99901.1 - 0.086 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 pKID domain Cutinase PF01083.17 EDN99902.1 - 2.6e-33 115.2 1.2 3.1e-33 115.0 0.8 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EDN99902.1 - 0.0006 19.4 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.6 EDN99902.1 - 0.0034 16.8 0.1 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EDN99902.1 - 0.0081 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN99902.1 - 0.079 12.8 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pyridox_oxidase PF01243.15 EDN99903.1 - 2.7e-13 49.7 0.0 1.9e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EDN99903.1 - 0.015 15.1 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.14 EDN99904.1 - 2.1e-12 47.1 0.0 4.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SUR7 PF06687.7 EDN99905.1 - 1.1e-34 119.9 9.2 1.3e-34 119.6 6.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EDN99905.1 - 0.00013 21.7 10.1 0.00013 21.7 7.0 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 EDN99905.1 - 0.12 12.1 8.6 0.13 12.1 2.9 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Peptidase_C65 PF10275.4 EDN99907.1 - 3.9e-72 242.5 0.0 4.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EDN99909.1 - 7.2e-19 68.0 1.8 1.6e-18 66.9 0.1 2.4 2 1 1 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EDN99909.1 - 1.2e-08 34.8 0.1 3.2e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF3173 PF11372.3 EDN99909.1 - 0.011 15.2 0.1 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) TPR_7 PF13176.1 EDN99909.1 - 0.014 15.1 0.5 9.2 6.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EDN99909.1 - 0.05 13.5 0.1 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 EDN99909.1 - 0.062 13.2 3.6 1.2 9.1 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN99909.1 - 5.3 7.0 6.4 3.8 7.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.3 EDN99910.1 - 5.8e-26 90.7 0.5 5.8e-26 90.7 0.4 4.3 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EDN99910.1 - 5.7e-14 51.8 12.5 5.7e-14 51.8 8.7 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.17 EDN99911.1 - 4.3e-39 133.5 0.0 6.3e-39 132.9 0.0 1.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN99911.1 - 2.5e-08 34.4 0.0 3.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN99911.1 - 0.00032 19.9 0.0 0.00056 19.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MIP PF00230.15 EDN99912.1 - 9.2e-47 159.4 9.5 1.3e-46 158.9 6.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein CAF-1_p150 PF11600.3 EDN99916.1 - 8.4 5.7 14.1 11 5.2 9.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dioxygenase_C PF00775.16 EDN99918.1 - 3.7e-49 166.4 0.0 5e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EDN99918.1 - 3.7e-13 49.2 0.0 5.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EDN99918.1 - 2.4e-05 24.3 0.0 0.00016 21.6 0.0 2.3 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EDN99918.1 - 0.036 13.8 0.4 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Cna protein B-type domain DUF4198 PF10670.4 EDN99918.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Lactonase PF10282.4 EDN99919.1 - 8.3e-19 67.8 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.2 EDN99920.1 - 3.2e-24 86.0 0.0 5.9e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN99920.1 - 1.7e-14 53.9 0.0 5e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN99920.1 - 2.1e-09 37.2 0.0 3.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EDN99920.1 - 2e-06 26.5 0.0 2.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EDN99920.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF4286 PF14114.1 EDN99920.1 - 0.00021 21.4 0.3 0.008 16.4 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) EthD PF07110.6 EDN99920.1 - 0.031 15.2 0.1 14 6.6 0.0 2.6 2 0 0 2 2 2 0 EthD domain SET PF00856.23 EDN99921.1 - 3.7e-24 85.8 0.1 4.1e-23 82.4 0.0 2.8 2 1 0 2 2 2 1 SET domain Glyco_hydro_35 PF01301.14 EDN99923.1 - 4.8e-81 272.5 1.9 1.5e-80 270.9 1.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EDN99923.1 - 4.4e-62 208.6 0.1 7.5e-62 207.9 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EDN99923.1 - 7.8e-50 167.8 8.7 1.2e-24 86.6 1.3 3.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EDN99923.1 - 1.2e-23 82.2 0.7 3.5e-23 80.7 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EDN99923.1 - 1.4e-05 24.4 0.4 2.4e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mod_r PF07200.8 EDN99924.1 - 0.0083 16.0 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 EDN99924.1 - 0.096 12.4 0.2 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GCK PF07802.6 EDN99925.1 - 0.16 12.1 0.5 0.3 11.2 0.3 1.4 1 0 0 1 1 1 0 GCK domain Catalase PF00199.14 EDN99926.1 - 2.1e-162 540.2 0.1 2.9e-162 539.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN99926.1 - 1.2e-20 73.1 0.1 2.9e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EDN99926.1 - 6.2e-10 38.7 0.0 2.2e-09 36.8 0.0 1.7 1 1 1 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 EDN99926.1 - 5e-07 29.1 0.0 9.3e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase LppC PF04348.8 EDN99926.1 - 0.0025 16.4 0.0 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 LppC putative lipoprotein Fungal_trans PF04082.13 EDN99927.1 - 6.6e-14 51.3 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN99927.1 - 5.1e-10 39.0 8.6 1.4e-09 37.6 5.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOZART1 PF12554.3 EDN99927.1 - 0.05 13.0 0.6 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Amidase PF01425.16 EDN99928.1 - 9.6e-48 163.1 0.0 2.6e-28 99.1 0.0 3.0 1 1 1 2 2 2 2 Amidase Ric8 PF10165.4 EDN99929.1 - 2.4e-94 316.6 7.9 5.8e-62 209.9 1.3 2.1 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn DUF1149 PF06619.6 EDN99929.1 - 0.2 11.5 2.1 0.22 11.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1149) His_Phos_2 PF00328.17 EDN99932.1 - 2.6e-31 109.2 0.0 4.2e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Zn_clus PF00172.13 EDN99933.1 - 2.2e-07 30.6 8.9 5.1e-07 29.4 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN99933.1 - 0.00033 19.3 0.0 0.00045 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Subtilosin_A PF11420.3 EDN99933.1 - 1 9.4 4.7 0.21 11.6 0.4 1.9 2 0 0 2 2 2 0 Bacteriocin subtilosin A ADH_zinc_N PF00107.21 EDN99934.1 - 4.6e-11 42.3 0.0 8.4e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN99934.1 - 1.3e-06 28.1 0.0 6.3e-06 25.9 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EDN99934.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EDN99934.1 - 0.024 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Zn_clus PF00172.13 EDN99935.1 - 4.3e-05 23.3 10.2 9.7e-05 22.1 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PagP PF07017.6 EDN99938.1 - 0.0099 15.2 0.4 0.16 11.3 0.1 2.1 1 1 1 2 2 2 2 Antimicrobial peptide resistance and lipid A acylation protein PagP DUF2597 PF10772.4 EDN99938.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) KRTAP PF11759.3 EDN99940.1 - 0.03 14.5 15.4 0.03 14.5 10.6 1.9 2 0 0 2 2 2 0 Keratin-associated matrix Solute_trans_a PF03619.11 EDN99941.1 - 6.7e-85 284.7 19.3 8.1e-85 284.4 13.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Toxin_7 PF05980.7 EDN99942.1 - 0.02 14.9 4.1 0.02 14.9 2.9 1.5 2 0 0 2 2 2 0 Toxin 7 Antifungal_pept PF11410.3 EDN99942.1 - 0.051 13.6 5.7 0.085 12.9 3.8 1.5 1 1 0 1 1 1 0 Antifungal peptide UPF0506 PF11703.3 EDN99942.1 - 0.85 9.6 7.3 18 5.4 5.6 2.0 1 1 1 2 2 2 0 UPF0506 Conotoxin PF02950.12 EDN99942.1 - 2.2 9.1 11.6 0.25 12.1 3.8 2.0 1 1 1 2 2 2 0 Conotoxin Amidoligase_2 PF12224.3 EDN99943.1 - 8.1e-28 97.7 0.7 3.9e-27 95.4 0.5 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme PAR1 PF06521.6 EDN99943.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 PAR1 protein CorA PF01544.13 EDN99944.1 - 9e-11 41.3 1.3 9e-11 41.3 0.9 3.6 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein PP2 PF14299.1 EDN99944.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Phloem protein 2 Mannosyl_trans3 PF11051.3 EDN99945.1 - 2.6e-72 243.4 0.1 2.5e-71 240.2 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative DUF605 PF04652.11 EDN99946.1 - 1.8 7.9 18.5 2.1 7.6 12.8 1.0 1 0 0 1 1 1 0 Vta1 like Shisa PF13908.1 EDN99946.1 - 1.9 8.6 15.6 7 6.7 10.8 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_hydro_3 PF00933.16 EDN99948.1 - 3.4e-09 36.1 0.0 4.1e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Anp1 PF03452.9 EDN99949.1 - 2e-108 361.6 0.0 2.6e-108 361.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EDN99949.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 C1_1 PF00130.17 EDN99950.1 - 0.08 12.6 1.1 0.26 11.0 0.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_hydro_3_C PF01915.17 EDN99955.1 - 3e-05 23.6 0.0 3.2e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3_C PF01915.17 EDN99956.1 - 3.5e-06 26.7 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF4267 PF14087.1 EDN99957.1 - 1.5e-16 59.9 4.0 1.8e-16 59.6 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) TraW_N PF12477.3 EDN99957.1 - 0.0036 17.2 0.6 0.01 15.7 0.4 1.8 1 0 0 1 1 1 1 Sex factor F TraW protein N terminal YhhN PF07947.9 EDN99957.1 - 0.22 10.8 2.7 0.22 10.8 0.3 1.8 1 1 1 2 2 2 0 YhhN-like protein adh_short PF00106.20 EDN99959.1 - 2.2e-19 69.9 0.0 2.8e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99959.1 - 1.4e-11 44.6 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99959.1 - 7.2e-08 32.3 0.0 9.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EDN99961.1 - 6.8e-15 55.3 0.1 1.1e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN99961.1 - 8e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN99961.1 - 0.00041 20.0 0.3 0.00072 19.2 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN99961.1 - 0.072 12.5 1.0 0.22 10.9 0.7 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDN99962.1 - 0.0025 17.6 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrbH PF07283.6 EDN99962.1 - 0.052 13.4 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Conjugal transfer protein TrbH RmlD_sub_bind PF04321.12 EDN99962.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EDN99962.1 - 0.084 12.1 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family RVT_2 PF07727.9 EDN99964.1 - 1.6e-70 236.9 0.0 2.9e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN99964.1 - 2.5e-11 43.7 0.0 8.4e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN99964.1 - 2e-08 33.7 0.0 6.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN99964.1 - 2.8e-05 23.8 0.4 6.2e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EDN99964.1 - 0.00037 20.0 0.6 0.00037 20.0 0.4 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EDN99964.1 - 0.0044 16.4 3.0 0.0044 16.4 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-Sec23_Sec24 PF04810.10 EDN99964.1 - 0.034 13.7 0.1 6.3 6.4 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Peptidase_S15 PF02129.13 EDN99965.1 - 1.2e-32 113.3 0.2 6.5e-32 111.0 0.1 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EDN99965.1 - 6.9e-21 75.1 0.0 9.4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EDN99965.1 - 0.002 18.0 0.1 0.0037 17.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3425 PF11905.3 EDN99966.1 - 8e-36 122.9 0.0 2.1e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HTH_Tnp_Tc5 PF03221.11 EDN99966.1 - 4.1e-14 52.1 2.5 5.8e-14 51.6 0.8 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HsbA PF12296.3 EDN99969.1 - 0.043 13.6 0.6 0.074 12.9 0.2 1.5 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DDE_1 PF03184.14 EDN99970.1 - 2.4e-36 124.9 0.1 3.4e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN99970.1 - 0.00059 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN99970.1 - 0.0032 16.9 0.0 0.0074 15.8 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN99970.1 - 0.0063 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EDN99970.1 - 0.029 14.6 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RNase_H PF00075.19 EDN99976.1 - 1.1e-14 54.8 0.0 2.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 RNase H AAA PF00004.24 EDN99976.1 - 6.7e-09 36.0 0.0 2e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN99976.1 - 3.2e-05 24.7 0.0 9.6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain zf-RVT PF13966.1 EDN99976.1 - 0.0045 17.2 0.1 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase NAD_kinase PF01513.16 EDN99978.1 - 1.1e-67 227.8 0.0 1.4e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 EDN99981.1 - 6.5e-05 23.2 0.0 7.4e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PTPA PF03095.10 EDN99982.1 - 5.9e-116 386.8 0.0 7.2e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-C2H2 PF00096.21 EDN99984.1 - 3.5e-06 27.0 24.9 0.00029 20.9 0.5 5.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN99984.1 - 0.017 15.4 0.9 0.017 15.4 0.6 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Sugar_tr PF00083.19 EDN99985.1 - 1.4e-115 386.4 26.4 1.8e-115 386.1 18.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN99985.1 - 7.8e-31 107.0 28.9 1e-22 80.3 5.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN99985.1 - 1.7e-11 43.1 27.6 1.4e-08 33.5 4.0 3.8 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EDN99985.1 - 0.0036 15.5 1.6 0.0036 15.5 1.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 EDN99985.1 - 0.17 11.8 6.7 0.1 12.6 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Sod_Cu PF00080.15 EDN99986.1 - 1.7e-13 50.9 0.1 2.3e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.14 EDN99989.1 - 7.1e-09 34.8 0.0 0.0062 15.3 0.0 3.3 2 1 1 3 3 3 3 Aminotransferase class-V DUF202 PF02656.10 EDN99991.1 - 0.037 14.2 5.3 0.2 11.9 3.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Zn_clus PF00172.13 EDN99992.1 - 2.1e-07 30.7 8.8 3.3e-07 30.1 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_assoc PF10600.4 EDN99992.1 - 0.0069 16.6 1.8 0.0069 16.6 1.3 3.0 3 1 0 3 3 3 1 PDZ-associated domain of NMDA receptors GSIII_N PF12437.3 EDN99992.1 - 0.083 12.2 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal SIR2 PF02146.12 EDN99996.1 - 9.4e-56 188.3 0.0 4.4e-55 186.1 0.0 1.8 2 0 0 2 2 2 1 Sir2 family Pex16 PF08610.5 EDN99996.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Pro-kuma_activ PF09286.6 EDN99998.1 - 1.5e-46 157.9 0.0 1.5e-45 154.7 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN99998.1 - 9.7e-05 21.6 0.1 0.00016 20.9 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Tox-REase-7 PF15649.1 EDO00001.1 - 0.49 10.5 4.0 3.3 7.9 0.5 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 adh_short PF00106.20 EDO00005.1 - 0.00013 21.9 0.3 0.00032 20.6 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF4131 PF13567.1 EDO00006.1 - 0.087 12.2 1.0 0.12 11.7 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4366 PF14283.1 EDO00006.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3634 PF12321.3 EDO00007.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) zf-RanBP PF00641.13 EDO00008.1 - 0.023 13.7 0.5 0.023 13.7 0.3 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Lung_7-TM_R PF06814.8 EDO00009.1 - 0.095 11.6 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Lung seven transmembrane receptor LSR PF05624.9 EDO00009.1 - 0.19 11.4 3.1 0.24 11.1 2.2 1.1 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Asp PF00026.18 EDO00011.1 - 1.5e-05 24.4 0.1 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.10 EDO00011.1 - 0.55 9.8 3.1 1.1 8.8 2.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1932 PF09130.6 EDO00014.1 - 4.1e-23 80.9 0.0 7.3e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EDO00014.1 - 5.1e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDO00014.1 - 1.4e-05 25.4 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EDO00014.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDO00014.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.17 EDO00015.1 - 9e-16 57.2 0.0 1.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00015.1 - 7.2e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00015.1 - 1.9e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EDO00015.1 - 0.0015 18.8 19.6 0.0015 18.8 13.6 4.6 4 1 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.6 EDO00015.1 - 0.68 9.8 2.9 0.73 9.7 0.0 2.3 3 0 0 3 3 3 0 RNA binding motif UQ_con PF00179.21 EDO00018.1 - 5.6e-24 84.1 0.0 6.8e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AOX PF01786.12 EDO00023.1 - 5.6e-90 300.2 0.0 7.2e-90 299.9 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase RRM_1 PF00076.17 EDO00027.1 - 5e-20 70.9 0.2 1.3e-19 69.5 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00027.1 - 8.7e-17 60.8 0.0 1.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00027.1 - 2.9e-08 33.4 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 EDO00028.1 - 1.5e-35 122.7 0.0 7.2e-35 120.5 0.0 1.8 1 1 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 EDO00029.1 - 2e-26 89.2 7.2 1.2e-06 27.3 0.2 5.4 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EDO00029.1 - 1.4e-23 82.8 1.8 1.2e-08 34.9 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EDO00029.1 - 3.7e-22 76.1 8.0 0.00051 19.7 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.1 EDO00029.1 - 2.8e-20 71.6 10.4 3.9e-10 39.2 0.0 4.8 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 EDO00029.1 - 1.2e-16 59.1 11.3 7.1e-05 21.9 0.1 4.9 5 0 0 5 5 5 4 EF hand POLO_box PF00659.13 EDO00029.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 POLO box duplicated region DUF1764 PF08576.5 EDO00030.1 - 0.009 16.7 1.2 0.011 16.5 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) NR_Repeat PF14046.1 EDO00030.1 - 2.8 7.7 7.0 0.53 10.0 1.9 2.1 2 1 0 2 2 2 0 Nuclear receptor repeat HET PF06985.6 EDO00031.1 - 4.7e-33 114.2 1.3 3.4e-32 111.5 0.9 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Destabilase PF05497.7 EDO00031.1 - 0.096 12.7 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Destabilase FAD_binding_4 PF01565.18 EDO00032.1 - 1.4e-16 60.2 0.0 2.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Ubiquitin_2 PF14560.1 EDO00033.1 - 0.012 15.8 1.3 0.015 15.4 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4614 PF15391.1 EDO00033.1 - 2.4 7.9 8.8 2.1 8.0 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) UPF0160 PF03690.8 EDO00033.1 - 2.8 7.2 9.8 3.3 7.0 6.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0160) PKI PF02827.11 EDO00033.1 - 7.7 6.7 9.1 5.6 7.1 4.8 2.0 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor AAA_11 PF13086.1 EDO00033.1 - 8.4 5.8 9.6 11 5.4 6.6 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L13e PF01294.13 EDO00035.1 - 7.7e-64 214.4 3.3 1e-63 214.0 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Mito_carr PF00153.22 EDO00037.1 - 2e-31 107.5 2.5 1.8e-18 66.0 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3602 PF12223.3 EDO00038.1 - 1e-14 54.6 10.7 6.2e-14 52.1 2.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) BAH PF01426.13 EDO00039.1 - 3.1e-07 30.1 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 BAH domain FANCL_C PF11793.3 EDO00039.1 - 8.9 6.3 8.5 0.4 10.6 1.7 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain YtxC PF08812.6 EDO00041.1 - 0.053 13.0 0.1 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family Toxin_8 PF07365.7 EDO00042.1 - 0.16 11.9 0.3 0.16 11.9 0.2 1.1 1 0 0 1 1 1 0 Alpha conotoxin precursor WD40 PF00400.27 EDO00043.1 - 4.8e-28 95.9 11.9 1.1e-07 31.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO00043.1 - 0.00057 18.7 0.0 0.26 10.0 0.0 3.0 2 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EDO00043.1 - 0.001 17.3 0.1 0.0041 15.3 0.4 1.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cyclin_N PF00134.18 EDO00043.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain HA2 PF04408.18 EDO00044.1 - 4.7e-26 90.7 0.0 1.8e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO00044.1 - 1.8e-24 85.7 0.0 1.8e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO00044.1 - 5.4e-13 48.6 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO00044.1 - 5.4e-07 29.2 0.0 1.4e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO00044.1 - 0.00046 20.3 0.2 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EDO00044.1 - 0.0042 16.9 0.2 0.86 9.3 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EDO00044.1 - 0.017 14.0 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EDO00044.1 - 0.021 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EDO00044.1 - 0.056 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC SRP54 PF00448.17 EDO00044.1 - 0.063 12.7 0.1 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EDO00044.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CVNH PF08881.5 EDO00045.1 - 1.7e-06 28.1 0.0 3.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 CVNH domain Pyr_redox_3 PF13738.1 EDO00046.1 - 3.1e-13 50.2 0.0 6.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO00046.1 - 1.2e-10 40.2 0.0 2.5e-10 39.1 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EDO00046.1 - 3.8e-09 36.5 0.0 2.1e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDO00046.1 - 9.8e-09 35.3 0.0 6.3e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO00046.1 - 1.1e-08 34.9 0.4 1.8e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO00046.1 - 6e-06 25.4 0.0 0.00013 21.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EDO00046.1 - 0.00016 20.8 0.0 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EDO00046.1 - 0.001 19.3 0.6 0.71 10.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO00046.1 - 0.0021 17.2 0.2 0.014 14.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EDO00046.1 - 0.0036 15.8 0.0 0.0086 14.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EDO00046.1 - 0.0037 16.2 0.1 0.02 13.8 0.0 2.2 3 1 0 4 4 4 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDO00046.1 - 0.005 15.5 1.6 0.021 13.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 EDO00046.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EDO00046.1 - 0.2 10.7 0.7 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EDO00047.1 - 1.1e-33 116.4 36.3 1.1e-33 116.4 25.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MutS_V PF00488.16 EDO00048.1 - 6.5e-84 280.9 0.0 1.1e-83 280.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO00048.1 - 1.4e-35 122.9 0.5 3.7e-35 121.5 0.4 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO00048.1 - 2.1e-27 95.3 0.0 5.4e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EDO00048.1 - 4.3e-10 39.6 0.7 7.8e-09 35.5 0.0 3.0 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 EDO00048.1 - 6e-09 36.0 0.1 2.4e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II EST1 PF10374.4 EDO00048.1 - 0.018 15.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Telomerase activating protein Est1 Prenyltrans PF00432.16 EDO00050.1 - 1.3e-62 206.9 8.1 2.5e-15 55.7 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO00050.1 - 2.1e-39 134.4 0.0 8.8e-16 58.3 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDO00050.1 - 2.8e-11 43.4 0.0 0.0001 22.2 0.0 3.5 1 1 2 3 3 3 2 Prenyltransferase-like UbiD PF01977.11 EDO00051.1 - 0.00029 19.4 0.0 0.00031 19.3 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavin_Reduct PF01613.13 EDO00052.1 - 1.5e-25 89.8 0.0 2.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain AIG2_2 PF13772.1 EDO00053.1 - 5.4e-07 29.6 0.3 1.5e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 AIG2-like family Methyltransf_9 PF08003.6 EDO00055.1 - 0.081 11.6 0.0 0.097 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) APH PF01636.18 EDO00056.1 - 1e-06 28.6 0.2 7.9e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO00056.1 - 1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.1 EDO00057.1 - 0.0065 16.0 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DHDPS PF00701.17 EDO00058.1 - 2.3e-43 147.8 0.0 2.7e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DDE_1 PF03184.14 EDO00059.1 - 8.7e-63 211.3 0.0 1.4e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO00059.1 - 2.1e-15 56.0 0.0 3.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO00059.1 - 5.9e-12 45.2 0.1 1.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO00059.1 - 2.1e-08 34.0 0.0 4.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDO00059.1 - 0.018 15.0 0.8 0.091 12.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.1 EDO00059.1 - 0.027 14.1 0.0 0.1 12.2 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Kinesin PF00225.18 EDO00061.1 - 1.8e-113 378.6 0.1 1.8e-113 378.6 0.0 2.4 2 1 0 2 2 2 1 Kinesin motor domain RolB_RolC PF02027.12 EDO00061.1 - 1.4 8.0 5.0 3 6.9 0.3 2.6 2 0 0 2 2 2 0 RolB/RolC glucosidase family UQ_con PF00179.21 EDO00062.1 - 3e-51 172.5 0.0 3.4e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO00062.1 - 7e-07 29.0 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO00062.1 - 0.03 14.2 0.1 0.051 13.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EDO00063.1 - 7e-87 290.7 0.7 1.4e-86 289.7 0.5 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDO00063.1 - 1.5e-38 130.9 2.4 2e-38 130.5 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDO00063.1 - 0.00013 21.5 1.6 0.00053 19.5 0.6 2.2 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EDO00063.1 - 0.18 11.4 3.9 11 5.7 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Frag1 PF10277.4 EDO00064.1 - 0.011 15.2 0.3 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Fungal_trans PF04082.13 EDO00070.1 - 6e-23 81.0 0.0 1.5e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO00070.1 - 2.7e-08 33.5 10.6 4.4e-08 32.9 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDO00071.1 - 6.4e-32 110.6 35.6 6.9e-31 107.2 9.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO00071.1 - 1.5e-06 27.0 4.4 1.5e-06 27.0 3.1 3.1 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EDO00071.1 - 0.043 12.2 23.0 0.0078 14.6 1.1 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein Mannosyl_trans3 PF11051.3 EDO00072.1 - 0.039 13.3 0.0 0.039 13.3 0.0 1.0 1 0 0 1 1 1 0 Mannosyltransferase putative Apc4_WD40 PF12894.2 EDO00072.1 - 0.05 13.1 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1014 PF06244.7 EDO00077.1 - 1.3e-17 64.1 14.9 3.9e-17 62.5 10.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) gpUL132 PF11359.3 EDO00077.1 - 1.4 8.1 6.2 0.28 10.4 0.2 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 Gluconate_2-dh3 PF13618.1 EDO00077.1 - 5.6 7.1 15.8 1 9.5 6.4 2.2 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FlgM PF04316.8 EDO00078.1 - 0.067 13.1 0.4 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF1604 PF07713.8 EDO00082.1 - 1.4e-38 130.5 2.4 3.7e-38 129.2 0.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EDO00082.1 - 2.8e-06 26.9 2.7 2.8e-06 26.9 1.9 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EDO00082.1 - 0.015 15.1 1.2 0.015 15.1 0.8 3.4 2 2 1 3 3 3 0 DExH-box splicing factor binding site Pkinase PF00069.20 EDO00083.1 - 3.2e-77 259.2 0.0 4.4e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00083.1 - 8.3e-40 136.4 0.1 5.5e-39 133.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EDO00083.1 - 1.3e-15 56.5 0.2 2.2e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EDO00083.1 - 6.9e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO00083.1 - 4.9e-05 22.4 0.0 0.00016 20.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO00083.1 - 0.0052 16.5 0.1 0.028 14.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EDO00083.1 - 0.0058 15.8 0.1 0.0093 15.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EDO00083.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EDO00083.1 - 0.051 12.9 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 RIO1 family Glyco_transf_15 PF01793.11 EDO00084.1 - 1.2e-96 323.5 18.2 5.1e-58 196.5 2.8 3.0 2 1 1 3 3 3 2 Glycolipid 2-alpha-mannosyltransferase Prog_receptor PF02161.10 EDO00085.1 - 4.5 5.9 10.0 4.9 5.8 6.9 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF1772 PF08592.6 EDO00086.1 - 2.8e-23 82.1 1.1 2.2e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Apolipoprotein PF01442.13 EDO00087.1 - 0.0016 17.9 8.2 0.86 9.0 2.3 3.7 3 2 1 4 4 4 2 Apolipoprotein A1/A4/E domain DUF445 PF04286.7 EDO00087.1 - 0.0036 16.8 10.9 0.0084 15.6 5.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF445) Peptidase_M41 PF01434.13 EDO00087.1 - 0.0088 15.5 6.0 0.009 15.5 2.1 2.4 2 1 1 3 3 3 1 Peptidase family M41 MgsA_C PF12002.3 EDO00087.1 - 0.015 15.0 0.4 0.046 13.4 0.2 1.9 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal XH PF03469.9 EDO00087.1 - 0.046 13.3 15.6 4.4 6.9 0.1 4.6 2 1 2 4 4 4 0 XH domain Phasin_2 PF09361.5 EDO00087.1 - 0.068 13.1 8.3 0.91 9.5 0.3 4.3 4 2 2 6 6 6 0 Phasin protein Globin PF00042.17 EDO00087.1 - 0.28 11.5 3.0 5.1 7.4 0.0 3.3 4 1 0 4 4 4 0 Globin MoCF_biosynth PF00994.19 EDO00087.1 - 0.4 10.0 2.0 0.96 8.8 1.4 1.7 1 1 0 1 1 1 0 Probable molybdopterin binding domain GnsAB PF08178.6 EDO00087.1 - 0.96 9.1 8.5 0.93 9.2 1.2 3.2 3 0 0 3 3 3 0 GnsA/GnsB family Prominin PF05478.6 EDO00087.1 - 1.5 6.2 3.7 8.8 3.7 0.8 2.6 1 1 0 2 2 2 0 Prominin DUF1664 PF07889.7 EDO00087.1 - 2.2 8.1 9.1 1.4 8.7 0.1 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CRT10 PF08728.5 EDO00088.1 - 2.7e-17 62.0 0.0 7e-12 44.1 0.0 2.9 2 1 0 2 2 2 2 CRT10 Pkinase PF00069.20 EDO00094.1 - 3.5e-55 186.9 0.0 6e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00094.1 - 2.3e-39 135.0 0.0 4e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO00094.1 - 0.0011 18.0 0.0 0.0026 16.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO00094.1 - 0.0047 16.0 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF865 PF05906.6 EDO00096.1 - 0.038 13.5 0.4 0.064 12.8 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Complex1_49kDa PF00346.14 EDO00098.1 - 3.4e-133 442.7 0.0 4.5e-133 442.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EDO00099.1 - 5e-22 78.1 0.0 1.5e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO00099.1 - 8.7e-14 50.3 0.0 1.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EDO00100.1 - 5.9e-35 120.0 0.1 1.3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.5 EDO00100.1 - 5.5e-30 102.9 0.0 1.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EDO00100.1 - 3.3e-25 87.4 0.4 5.8e-25 86.6 0.3 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO00100.1 - 1.2e-11 43.8 1.2 1.2e-11 43.8 0.8 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Ecm33 PF12454.3 EDO00100.1 - 0.13 12.1 2.1 0.25 11.2 1.5 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.15 EDO00100.1 - 0.14 12.2 0.1 0.53 10.3 0.1 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Telomere_reg-2 PF10193.4 EDO00102.1 - 1.2e-40 138.3 0.0 2.2e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein FAD_binding_3 PF01494.14 EDO00103.1 - 2.6e-12 46.5 5.0 5.1e-11 42.2 0.4 3.3 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 EDO00103.1 - 6e-07 28.6 0.1 0.021 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EDO00103.1 - 1.2e-05 24.3 0.0 0.0001 21.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.19 EDO00103.1 - 9.7e-05 21.6 0.0 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EDO00103.1 - 0.0045 15.9 0.8 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EDO00103.1 - 0.0069 16.1 0.7 1 9.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDO00103.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDO00103.1 - 0.17 11.9 0.2 1.1 9.2 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WLM PF08325.5 EDO00104.1 - 6.3e-51 172.8 1.6 1e-50 172.2 0.0 2.1 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EDO00104.1 - 5.6e-08 32.8 1.0 1.2e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 Mif2_N PF15624.1 EDO00104.1 - 0.0039 17.7 2.8 0.0084 16.6 2.0 1.5 1 0 0 1 1 1 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal zf-RanBP PF00641.13 EDO00104.1 - 0.29 10.2 9.8 0.25 10.4 1.5 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 EDO00104.1 - 2 8.3 5.6 5.7 6.8 3.9 1.8 1 0 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EDO00104.1 - 2.1 7.8 7.3 0.24 10.8 1.0 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Kelch_3 PF13415.1 EDO00105.1 - 2.8e-26 91.0 23.4 3.5e-09 36.5 0.0 6.9 9 0 0 9 9 9 4 Galactose oxidase, central domain DUF4110 PF13422.1 EDO00105.1 - 2.4e-25 88.1 0.0 2.4e-25 88.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EDO00105.1 - 2.7e-24 84.6 15.7 1.9e-07 30.6 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO00105.1 - 3.3e-15 55.6 11.8 1.3e-07 31.4 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EDO00105.1 - 2.9e-13 49.3 7.6 0.00028 20.9 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EDO00105.1 - 5.8e-13 48.0 6.1 0.018 14.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EDO00105.1 - 1.4e-10 40.5 7.3 3.6e-07 29.6 0.1 5.5 5 1 0 5 5 5 1 Kelch motif SGT1 PF07093.6 EDO00105.1 - 8.2 4.6 30.5 0.043 12.1 10.4 2.1 2 0 0 2 2 2 0 SGT1 protein Abhydrolase_6 PF12697.2 EDO00106.1 - 0.00013 21.9 0.0 0.00077 19.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO00106.1 - 0.0056 16.4 0.0 0.026 14.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO00106.1 - 0.043 13.3 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioredoxin PF00085.15 EDO00107.1 - 5.9e-63 209.0 4.4 4.3e-32 109.8 0.0 4.0 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EDO00107.1 - 5.7e-55 185.9 4.1 1.9e-38 132.1 0.1 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDO00107.1 - 3.7e-11 42.8 0.0 0.00042 20.2 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 EDO00107.1 - 7.4e-11 41.4 0.9 4e-10 39.0 0.2 2.1 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.1 EDO00107.1 - 2.5e-10 40.5 3.5 0.00058 20.0 0.3 4.8 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO00107.1 - 2.6e-10 40.2 0.1 0.0028 17.7 0.0 4.6 3 3 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EDO00107.1 - 8.8e-06 25.4 0.3 0.023 14.3 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EDO00107.1 - 0.00053 19.5 6.4 0.39 10.2 0.0 4.0 4 1 0 4 4 4 2 Redoxin Thioredoxin_3 PF13192.1 EDO00107.1 - 0.03 14.1 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EDO00107.1 - 0.35 10.8 8.1 17 5.3 0.1 4.3 3 2 0 3 3 3 0 Thioredoxin DUF2639 PF11121.3 EDO00108.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Annexin PF00191.15 EDO00109.1 - 1.6 8.6 3.9 3.3 7.6 1.3 2.1 2 0 0 2 2 2 0 Annexin Mon1 PF03164.9 EDO00110.1 - 1.1e-93 314.1 0.0 1.3e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 IFRD_C PF04836.7 EDO00110.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-related protein conserved region Dopey_N PF04118.9 EDO00111.1 - 2.2e-120 401.0 0.0 5.8e-120 399.7 0.0 1.7 1 0 0 1 1 1 1 Dopey, N-terminal HEAT_EZ PF13513.1 EDO00111.1 - 0.032 14.7 1.1 48 4.6 0.1 4.2 3 0 0 3 3 3 0 HEAT-like repeat zf-H2C2_2 PF13465.1 EDO00114.1 - 1.7e-10 40.6 13.9 1.1e-06 28.5 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDO00114.1 - 4.6e-09 36.0 14.6 1.5e-05 25.0 2.1 3.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO00114.1 - 1.3e-07 31.3 9.5 0.00012 22.1 1.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDO00114.1 - 4.5e-05 23.4 2.0 0.00014 21.9 1.4 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO00114.1 - 0.0005 20.1 5.8 0.00096 19.2 1.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO00114.1 - 0.0056 16.5 8.4 0.039 13.8 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDO00114.1 - 0.056 13.5 2.1 0.064 13.3 0.7 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EDO00114.1 - 0.48 10.1 5.4 5.5 6.7 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EDO00114.1 - 3.9 7.3 7.6 33 4.3 5.3 2.3 1 1 0 1 1 1 0 BED zinc finger RRM_1 PF00076.17 EDO00117.1 - 6.2e-30 102.6 0.5 8.4e-13 47.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00117.1 - 8e-20 70.5 0.0 9.3e-06 25.5 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00117.1 - 7.5e-17 60.9 0.0 9.7e-07 28.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HhH-GPD PF00730.20 EDO00118.1 - 2.3e-10 40.7 0.0 3.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDO00118.1 - 0.0004 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SNase PF00565.12 EDO00119.1 - 2.7e-25 88.7 0.2 3.7e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rax2 PF12768.2 EDO00122.1 - 5.2e-85 285.0 40.3 4.2e-65 219.7 1.7 7.5 3 3 2 7 7 7 5 Cortical protein marker for cell polarity Kelch_1 PF01344.20 EDO00122.1 - 0.055 13.0 0.0 0.055 13.0 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Reg_prop PF07494.6 EDO00122.1 - 0.076 13.0 2.8 18 5.8 0.0 4.8 4 0 0 4 4 4 0 Two component regulator propeller VRR_NUC PF08774.6 EDO00123.1 - 1.3e-14 54.0 0.2 3.3e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.8 EDO00124.1 - 9.1e-14 50.6 0.0 1.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 EDO00125.1 - 1.1e-30 105.2 0.1 2.1e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EDO00125.1 - 1.9e-22 78.7 0.0 2.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EDO00125.1 - 0.025 14.2 0.1 0.056 13.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain zf-3CxxC PF13695.1 EDO00126.1 - 8.1e-09 35.6 1.0 2.9e-08 33.8 0.7 1.8 1 1 0 1 1 1 1 Zinc-binding domain Med4 PF10018.4 EDO00127.1 - 1.9e-17 63.2 3.9 2.4e-17 62.9 2.7 1.0 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 U79_P34 PF03064.11 EDO00127.1 - 0.027 14.0 1.5 0.032 13.7 1.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 His_Phos_1 PF00300.17 EDO00129.1 - 4.7e-08 33.2 0.4 9.3e-07 29.0 0.1 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Myosin_HC-like PF07058.6 EDO00129.1 - 0.0038 16.3 5.6 0.0059 15.7 3.9 1.2 1 0 0 1 1 1 1 Myosin II heavy chain-like Peptidase_C13 PF01650.13 EDO00130.1 - 1.3e-25 90.1 0.1 1.8e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Methyltransf_2 PF00891.13 EDO00131.1 - 2.8e-05 23.4 0.0 4.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EDO00131.1 - 0.032 13.2 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 EDO00131.1 - 0.049 12.5 0.5 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Dimerisation PF08100.6 EDO00131.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.1 EDO00132.1 - 3.3e-18 65.9 0.0 5.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO00132.1 - 1.3e-07 32.2 0.0 2e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO00132.1 - 2.1e-06 28.0 0.1 2e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO00132.1 - 5e-06 26.9 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO00132.1 - 0.00011 21.8 0.0 0.0016 18.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO00132.1 - 0.00028 21.1 0.0 0.0011 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO00132.1 - 0.0056 15.8 0.0 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDO00132.1 - 0.0088 16.0 0.0 0.075 13.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDO00132.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MSP1_C PF07462.6 EDO00132.1 - 1.2 7.4 10.1 1.6 7.0 7.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PLA2_B PF01735.13 EDO00132.1 - 1.3 7.0 6.4 1.8 6.6 4.4 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DUF4592 PF15262.1 EDO00132.1 - 2 8.9 13.3 1.2 9.6 5.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Dicty_REP PF05086.7 EDO00132.1 - 3.9 5.1 14.5 5.3 4.6 10.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UQ_con PF00179.21 EDO00134.1 - 4.6e-34 116.8 0.0 5.9e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO00134.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Glyco_trans_1_4 PF13692.1 EDO00136.1 - 1.4e-24 86.7 0.0 2.5e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EDO00138.1 - 3.6e-54 183.7 0.9 4.4e-54 183.4 0.6 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EDO00138.1 - 0.0022 17.0 28.5 0.019 14.0 15.6 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter DUF1449 PF07290.6 EDO00138.1 - 0.047 13.0 0.1 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) NicO PF03824.11 EDO00138.1 - 0.99 8.6 14.0 2.3 7.4 9.7 1.6 1 1 0 1 1 1 0 High-affinity nickel-transport protein Syncollin PF15138.1 EDO00140.1 - 0.074 12.9 1.0 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 Syncollin ET PF01684.11 EDO00140.1 - 0.11 12.4 4.7 0.23 11.5 3.3 1.5 1 1 0 1 1 1 0 ET module Serpentine_r_xa PF03383.10 EDO00141.1 - 0.0023 17.6 3.6 0.0023 17.6 2.5 2.1 2 0 0 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa FmdA_AmdA PF03069.10 EDO00143.1 - 3.5e-54 183.8 0.0 3.5e-30 104.9 0.0 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family TFCD_C PF12612.3 EDO00144.1 - 2.3e-21 76.0 0.4 1.2e-20 73.7 0.0 2.5 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EDO00144.1 - 0.014 15.4 6.8 0.36 11.0 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO00144.1 - 0.037 14.4 0.1 1.2 9.5 0.0 3.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDO00144.1 - 0.051 14.0 10.2 2.7 8.5 0.1 5.6 6 0 0 6 6 6 0 HEAT-like repeat Cupin_8 PF13621.1 EDO00145.1 - 4.4e-37 127.9 0.0 8.8e-37 126.9 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EDO00145.1 - 2.5e-08 33.5 0.0 1.6e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EDO00145.1 - 0.0014 18.8 0.0 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EDO00145.1 - 0.13 11.7 0.1 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Aldolase_II PF00596.16 EDO00146.1 - 1.9e-44 151.4 0.1 2.5e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Abhydrolase_3 PF07859.8 EDO00147.1 - 1e-28 100.3 0.0 1.4e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDO00147.1 - 4.4e-05 22.2 0.0 5.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDO00147.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EDO00147.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Nol1_Nop2_Fmu PF01189.12 EDO00148.1 - 1.9e-31 109.5 0.0 5.6e-22 78.4 0.0 3.8 3 1 1 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EDO00148.1 - 0.0057 16.6 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain RNA_pol_Rpb5_C PF01191.14 EDO00149.1 - 3.7e-34 116.1 0.2 7.3e-34 115.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EDO00149.1 - 1.8e-31 108.4 0.1 2.9e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain APG6 PF04111.7 EDO00150.1 - 0.00019 20.5 19.7 0.00019 20.5 13.6 3.2 3 0 0 3 3 3 1 Autophagy protein Apg6 Complex1_LYR_1 PF13232.1 EDO00150.1 - 6.8 6.9 9.1 1.6 9.0 3.1 2.3 2 0 0 2 2 2 0 Complex1_LYR-like APG6 PF04111.7 EDO00151.1 - 0.0075 15.3 0.6 0.0089 15.1 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Cortex-I_coil PF09304.5 EDO00151.1 - 0.012 15.6 4.7 0.023 14.7 3.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil CASP_C PF08172.7 EDO00151.1 - 0.017 14.1 0.7 0.024 13.6 0.5 1.3 1 0 0 1 1 1 0 CASP C terminal BicD PF09730.4 EDO00151.1 - 0.024 13.0 0.9 0.033 12.5 0.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D BBP1_C PF15272.1 EDO00151.1 - 0.03 13.8 0.6 0.041 13.4 0.4 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Shugoshin_N PF07558.6 EDO00151.1 - 0.085 12.5 0.1 0.085 12.5 0.0 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EDO00151.1 - 1.2 8.6 8.1 4 6.9 0.9 2.9 1 1 2 3 3 3 0 Septum formation initiator RVT_1 PF00078.22 EDO00152.1 - 1.9e-37 128.6 0.0 3.1e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDO00152.1 - 4.3e-12 45.6 0.0 1.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDO00152.1 - 0.014 15.3 0.2 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family GTP1_OBG PF01018.17 EDO00155.1 - 2e-36 125.0 6.0 4.7e-28 97.8 2.5 2.7 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 EDO00155.1 - 1.6e-21 76.3 0.0 2.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO00155.1 - 7.2e-07 28.6 0.0 2e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDO00155.1 - 0.078 13.4 0.0 0.27 11.7 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EDO00155.1 - 0.092 13.0 0.0 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Arf PF00025.16 EDO00155.1 - 0.16 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Pyr_redox_3 PF13738.1 EDO00156.1 - 4.2e-22 79.2 0.0 1e-21 77.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO00156.1 - 2.6e-09 36.9 0.4 1.2e-07 31.6 0.2 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EDO00156.1 - 8.4e-06 25.9 0.8 0.0068 16.5 0.0 2.9 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EDO00156.1 - 1.2e-05 23.7 0.0 5e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.19 EDO00156.1 - 1.3e-05 24.2 0.2 2.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO00156.1 - 2.3e-05 24.3 0.0 0.0085 15.9 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO00156.1 - 0.0002 20.5 1.5 0.00064 18.8 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EDO00156.1 - 0.00066 19.8 0.0 0.11 12.7 0.0 3.0 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EDO00156.1 - 0.0027 18.0 0.6 3.8 7.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO00156.1 - 0.0082 15.0 1.4 0.028 13.3 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDO00156.1 - 0.012 15.4 0.2 0.96 9.2 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EDO00156.1 - 0.036 13.2 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EDO00156.1 - 0.063 12.3 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDO00156.1 - 0.064 12.1 0.0 0.22 10.3 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 EDO00156.1 - 0.071 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.12 EDO00156.1 - 0.087 11.9 0.2 0.38 9.8 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Mito_carr PF00153.22 EDO00159.1 - 1.4e-59 197.8 5.6 5.6e-21 74.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 EDO00159.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Pantoate_transf PF02548.10 EDO00160.1 - 0.028 13.5 0.0 0.028 13.5 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase FMO-like PF00743.14 EDO00163.1 - 6.6e-33 113.7 0.0 1.2e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDO00163.1 - 1.1e-22 81.1 0.0 4.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDO00163.1 - 1.2e-10 41.6 0.0 5.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO00163.1 - 5e-10 38.8 0.0 1.6e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EDO00163.1 - 2e-09 37.0 0.1 2.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDO00163.1 - 2.7e-09 36.8 0.3 1.2e-08 34.8 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDO00163.1 - 9e-09 35.2 0.1 0.00057 19.6 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO00163.1 - 1.8e-08 34.6 0.7 8.7e-05 22.8 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO00163.1 - 1.8e-07 30.3 0.2 1.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EDO00163.1 - 6.8e-05 22.0 0.6 0.00027 20.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EDO00163.1 - 0.00027 20.1 0.1 0.55 9.3 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EDO00163.1 - 0.00039 19.0 0.1 0.00094 17.7 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EDO00163.1 - 0.00055 19.0 0.1 0.00098 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EDO00163.1 - 0.0012 18.9 0.1 0.27 11.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO00163.1 - 0.0038 17.4 0.0 0.066 13.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EDO00163.1 - 0.004 16.0 0.1 0.0075 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EDO00163.1 - 0.0046 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EDO00163.1 - 0.0059 15.7 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO00163.1 - 0.0061 15.4 0.0 0.019 13.8 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_2 PF03446.10 EDO00163.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EDO00163.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EDO00163.1 - 0.018 14.6 4.4 0.054 13.0 0.0 2.8 4 0 0 4 4 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_red PF03358.10 EDO00163.1 - 0.065 12.7 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 NADPH-dependent FMN reductase NAD_Gly3P_dh_N PF01210.18 EDO00163.1 - 0.11 12.2 0.1 0.47 10.1 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EDO00163.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding CDC45 PF02724.9 EDO00164.1 - 5.3e-253 840.6 6.6 6.8e-251 833.6 4.6 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 EDO00164.1 - 2.1e-05 24.3 8.1 2.1e-05 24.3 5.6 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF605 PF04652.11 EDO00165.1 - 0.0037 16.7 17.7 0.0037 16.7 12.3 2.1 2 0 0 2 2 2 1 Vta1 like Peptidase_S58 PF03576.9 EDO00166.1 - 5.8e-08 32.2 1.3 0.0061 15.7 0.0 2.2 1 1 1 2 2 2 2 Peptidase family S58 zf-rbx1 PF12678.2 EDO00168.1 - 0.065 13.3 2.8 0.16 12.0 1.6 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger FAD_binding_4 PF01565.18 EDO00169.1 - 1.4e-21 76.4 1.3 2.4e-21 75.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDO00169.1 - 0.02 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like zf-CCHC PF00098.18 EDO00170.1 - 0.0023 17.7 6.0 0.0036 17.1 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDO00170.1 - 0.0057 16.9 0.9 0.013 15.7 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EDO00170.1 - 0.015 15.6 0.7 0.022 15.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EDO00170.1 - 0.035 14.0 2.2 0.057 13.3 1.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor ATXN-1_C PF12547.3 EDO00170.1 - 0.2 11.6 2.6 0.72 9.8 0.0 2.9 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator Herpes_BLRF2 PF05812.7 EDO00170.1 - 0.35 10.6 5.5 7.2 6.4 0.8 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DDE_1 PF03184.14 EDO00171.1 - 9.8e-18 64.0 0.0 1.1e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_3 PF01494.14 EDO00173.1 - 8.6e-15 54.6 0.9 0.00015 20.9 0.0 3.1 2 1 0 3 3 3 3 FAD binding domain DAO PF01266.19 EDO00173.1 - 2.8e-07 29.7 5.2 0.0099 14.8 2.9 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO00173.1 - 0.00011 21.2 2.4 0.00018 20.5 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO00173.1 - 0.0006 19.7 2.6 0.0011 18.8 1.8 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO00173.1 - 0.001 19.0 2.4 0.0031 17.5 1.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EDO00173.1 - 0.0025 16.7 1.3 0.0025 16.7 0.9 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EDO00173.1 - 0.027 13.1 1.0 2 6.9 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EDO00173.1 - 0.036 12.5 1.3 0.055 11.9 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EDO00173.1 - 0.078 12.5 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EDO00173.1 - 0.085 13.2 0.5 0.23 11.9 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDO00173.1 - 0.097 11.5 0.6 0.2 10.5 0.4 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EDO00173.1 - 0.14 11.1 1.8 0.21 10.6 1.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO00173.1 - 0.15 12.1 0.1 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFA PF04828.9 EDO00174.1 - 0.00014 21.6 7.9 0.0039 17.1 1.9 2.7 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme HCV_env PF01539.12 EDO00174.1 - 0.0057 16.1 1.9 0.011 15.2 0.1 2.0 2 0 0 2 2 2 1 Hepatitis C virus envelope glycoprotein E1 VKG_Carbox PF05090.9 EDO00176.1 - 0.00093 18.1 0.1 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase DEAD PF00270.24 EDO00177.1 - 2.2e-41 141.1 0.3 5.9e-41 139.7 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO00177.1 - 8.5e-21 73.6 1.9 1.9e-20 72.5 0.8 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO00177.1 - 0.0037 17.1 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO00177.1 - 0.084 13.0 0.2 0.37 10.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain SecA_DEAD PF07517.9 EDO00177.1 - 0.16 11.2 1.7 0.43 9.8 1.2 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain WD40 PF00400.27 EDO00179.1 - 2.1e-24 84.4 22.4 7.2e-08 32.0 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO00179.1 - 0.00044 20.0 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A 2OG-FeII_Oxy_2 PF13532.1 EDO00180.1 - 1.9e-34 119.1 0.0 2.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EDO00180.1 - 6.5e-10 38.7 2.6 1.3e-09 37.8 1.8 1.5 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EDO00180.1 - 0.021 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DinI PF06183.8 EDO00180.1 - 0.025 14.6 0.2 0.089 12.8 0.0 2.0 2 0 0 2 2 2 0 DinI-like family Glyco_hydro_61 PF03443.9 EDO00181.1 - 4.7e-72 242.3 2.4 5.3e-72 242.1 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.17 EDO00181.1 - 0.0017 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain HET PF06985.6 EDO00182.1 - 1.2e-18 67.6 0.0 1.8e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Luteo_Vpg PF01659.11 EDO00184.1 - 0.074 12.7 1.7 0.083 12.5 1.2 1.1 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein HTH_psq PF05225.11 EDO00194.1 - 0.057 12.9 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain P68HR PF08061.6 EDO00194.1 - 0.084 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 P68HR (NUC004) repeat AXE1 PF05448.7 EDO00194.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Trm112p PF03966.11 EDO00197.1 - 1.6e-16 60.4 0.4 2.1e-16 60.0 0.3 1.2 1 0 0 1 1 1 1 Trm112p-like protein RRN7 PF11781.3 EDO00197.1 - 0.028 13.9 0.2 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-NADH-PPase PF09297.6 EDO00197.1 - 0.033 13.6 0.1 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EDO00197.1 - 0.037 13.8 0.2 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.1 EDO00197.1 - 0.059 12.8 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DDE_1 PF03184.14 EDO00198.1 - 8.4e-21 74.1 1.5 2.2e-11 43.3 0.1 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO00198.1 - 1.9e-14 53.2 0.0 5e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain LRR_8 PF13855.1 EDO00199.1 - 0.00011 21.9 4.5 0.75 9.5 0.0 5.1 5 1 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EDO00199.1 - 0.00023 20.9 13.9 0.41 10.8 0.0 7.6 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 EDO00199.1 - 0.00049 19.6 5.3 8.8 6.0 0.0 5.6 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO00199.1 - 0.0024 17.6 6.5 11 6.5 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 EDO00199.1 - 0.006 16.5 2.8 38 5.1 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat Vps39_2 PF10367.4 EDO00199.1 - 0.059 13.5 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF844 PF05815.6 EDO00199.1 - 6.9 5.4 6.1 3.6 6.3 1.7 2.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF844) SNF2_N PF00176.18 EDO00200.1 - 5.6e-57 192.8 0.0 8.3e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO00200.1 - 1.4e-12 47.3 0.0 3.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EDO00200.1 - 4.5e-06 26.2 13.3 4.5e-06 26.2 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO00200.1 - 4.5e-05 23.3 11.7 4.5e-05 23.3 8.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO00200.1 - 0.00021 21.0 11.8 0.00021 21.0 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.3 EDO00200.1 - 0.63 9.6 8.2 0.36 10.3 3.6 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MFS_1 PF07690.11 EDO00201.1 - 1.9e-41 141.9 60.6 5.7e-40 137.1 42.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO00201.1 - 0.0011 17.6 8.0 0.0011 17.6 5.5 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 EDO00202.1 - 2.4e-14 52.8 0.0 8.8e-14 51.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO00202.1 - 1.1e-10 41.2 9.2 2.2e-10 40.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EDO00205.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDO00205.1 - 0.13 10.8 0.0 0.65 8.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) BON PF04972.12 EDO00205.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 BON domain HTH_Tnp_Tc5 PF03221.11 EDO00206.1 - 1.3e-07 31.3 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDO00206.1 - 3e-07 29.8 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SPACA7 PF15307.1 EDO00206.1 - 0.069 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 HTH_3 PF01381.17 EDO00206.1 - 0.1 12.4 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix Zw10 PF06248.8 EDO00208.1 - 1e-09 37.1 5.1 6.9e-07 27.8 0.0 3.8 2 1 2 4 4 4 2 Centromere/kinetochore Zw10 RNase_H PF00075.19 EDO00208.1 - 0.011 16.0 2.7 0.1 12.9 1.3 2.7 3 0 0 3 3 3 0 RNase H Tropomyosin_1 PF12718.2 EDO00208.1 - 0.18 11.6 7.9 0.39 10.5 5.4 1.5 1 0 0 1 1 1 0 Tropomyosin like Peptidase_M16_C PF05193.16 EDO00209.1 - 2.7e-13 50.0 0.0 1.4e-06 28.1 0.0 3.2 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO00209.1 - 1.6e-06 27.9 0.0 2.8e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) CobT PF06213.7 EDO00209.1 - 0.11 11.5 10.6 0.18 10.9 7.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.6 EDO00209.1 - 0.34 8.7 6.6 0.51 8.1 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen N-SET PF11764.3 EDO00210.1 - 1.8e-43 148.3 0.4 1.8e-43 148.3 0.3 2.8 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EDO00210.1 - 3.6e-24 85.8 0.2 3.6e-24 85.8 0.1 3.7 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 EDO00210.1 - 6.6e-23 79.7 0.1 1.6e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Tropomyosin_1 PF12718.2 EDO00212.1 - 3.6e-51 172.7 33.1 4.1e-51 172.5 22.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EDO00212.1 - 1.5e-09 37.3 31.9 4.6e-05 22.6 10.4 2.6 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 EDO00212.1 - 3e-05 23.9 29.3 0.00051 19.9 1.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 EDO00212.1 - 0.00032 18.9 25.8 0.00036 18.7 17.9 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 EDO00212.1 - 0.00063 18.9 27.1 0.00078 18.6 18.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 EDO00212.1 - 0.0016 18.4 7.6 0.0016 18.4 5.3 2.4 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein Mod_r PF07200.8 EDO00212.1 - 0.002 18.0 23.0 0.18 11.7 10.9 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.7 EDO00212.1 - 0.0024 17.6 16.6 0.0044 16.7 3.1 2.1 1 1 1 2 2 2 1 Laminin Domain II TMF_DNA_bd PF12329.3 EDO00212.1 - 0.0035 17.1 31.1 0.026 14.3 9.6 2.7 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding ERM PF00769.14 EDO00212.1 - 0.0062 16.1 34.5 0.013 15.0 9.9 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF3166 PF11365.3 EDO00212.1 - 0.0064 16.9 16.0 0.014 15.8 6.8 3.2 1 1 3 4 4 4 1 Protein of unknown function (DUF3166) Myosin_tail_1 PF01576.14 EDO00212.1 - 0.0072 14.1 30.7 0.0092 13.7 21.3 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 EDO00212.1 - 0.008 15.7 28.3 0.04 13.5 15.3 2.3 1 1 1 2 2 2 1 IncA protein EzrA PF06160.7 EDO00212.1 - 0.0082 14.3 21.6 0.062 11.4 2.4 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 EDO00212.1 - 0.0098 15.6 28.6 0.12 12.0 6.9 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EDO00212.1 - 0.012 14.6 32.5 0.099 11.6 10.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EDO00212.1 - 0.014 15.2 16.4 1.1 9.1 2.5 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EDO00212.1 - 0.018 14.2 2.3 0.6 9.2 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EDO00212.1 - 0.023 14.6 25.5 1.8 8.6 2.4 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 EDO00212.1 - 0.026 14.3 28.4 1.3 8.7 11.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EDO00212.1 - 0.037 13.9 29.8 0.054 13.3 6.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EDO00212.1 - 0.076 10.8 15.2 0.093 10.5 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BRE1 PF08647.6 EDO00212.1 - 0.1 12.5 26.3 0.29 11.1 3.2 2.5 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.6 EDO00212.1 - 0.12 10.9 25.5 0.028 13.1 8.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MAD PF05557.8 EDO00212.1 - 0.16 10.0 25.8 0.42 8.6 17.9 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Fib_alpha PF08702.5 EDO00212.1 - 0.2 11.7 15.8 0.19 11.8 2.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 EDO00212.1 - 0.24 10.9 23.2 0.26 10.8 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3287 PF11690.3 EDO00212.1 - 0.25 11.4 10.6 0.092 12.8 1.5 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) Atg14 PF10186.4 EDO00212.1 - 0.27 10.1 22.7 0.1 11.5 9.5 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 EDO00212.1 - 0.27 11.1 29.4 10 6.1 0.2 5.0 1 1 3 4 4 4 0 bZIP transcription factor IFT46_B_C PF12317.3 EDO00212.1 - 0.28 10.5 7.9 0.033 13.5 1.6 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Cortex-I_coil PF09304.5 EDO00212.1 - 0.3 11.1 27.1 4 7.5 5.1 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Filament PF00038.16 EDO00212.1 - 0.31 10.4 25.6 1.4 8.2 17.7 1.9 1 1 0 1 1 1 0 Intermediate filament protein TMF_TATA_bd PF12325.3 EDO00212.1 - 0.33 10.6 25.1 3 7.5 12.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 EDO00212.1 - 0.42 10.9 35.1 2 8.7 7.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Lebercilin PF15619.1 EDO00212.1 - 0.43 9.9 30.0 0.58 9.5 8.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.4 EDO00212.1 - 0.46 10.6 20.6 0.27 11.4 3.5 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltrn_RNA_4 PF09936.4 EDO00212.1 - 0.49 9.8 3.8 0.44 10.0 1.9 1.4 1 1 0 1 1 1 0 SAM-dependent RNA methyltransferase TBPIP PF07106.8 EDO00212.1 - 0.59 9.6 24.9 2.1 7.8 6.7 2.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MIS13 PF08202.6 EDO00212.1 - 0.6 9.1 18.7 0.23 10.4 1.1 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family NPV_P10 PF05531.7 EDO00212.1 - 0.62 10.3 10.2 21 5.4 0.1 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 EDO00212.1 - 0.63 10.4 24.1 2.3e+03 -1.1 16.7 3.0 1 1 0 1 1 0 0 Protein of unknown function (DUF972) Herpes_pp85 PF04637.7 EDO00212.1 - 0.72 8.0 4.4 0.23 9.6 0.9 1.6 1 1 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mnd1 PF03962.10 EDO00212.1 - 0.79 9.3 29.1 0.63 9.6 6.8 2.2 1 1 1 2 2 2 0 Mnd1 family DUF3450 PF11932.3 EDO00212.1 - 0.95 8.6 23.1 3.8 6.7 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HalX PF08663.5 EDO00212.1 - 0.97 9.4 17.6 7.1 6.6 0.0 4.2 2 2 2 4 4 4 0 HalX domain DUF4140 PF13600.1 EDO00212.1 - 1 9.8 22.4 1.5 9.2 3.1 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 EDO00212.1 - 1.2 7.5 24.8 0.98 7.8 5.5 2.0 1 1 1 2 2 2 0 AAA domain Fmp27_WPPW PF10359.4 EDO00212.1 - 1.2 7.4 21.6 0.09 11.1 4.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.7 EDO00212.1 - 1.4 8.7 14.1 1.6 8.5 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HAP1_N PF04849.8 EDO00212.1 - 1.4 7.8 25.9 83 1.9 18.0 3.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Syntaxin-6_N PF09177.6 EDO00212.1 - 1.4 9.3 16.5 5.1 7.5 1.2 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal CDC37_N PF03234.9 EDO00212.1 - 1.7 8.9 20.5 5.2 7.3 14.2 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3584 PF12128.3 EDO00212.1 - 1.7 5.8 25.3 2.6 5.2 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NABP PF07990.7 EDO00212.1 - 1.9 7.6 3.8 2.1 7.5 2.6 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP SPX PF03105.14 EDO00212.1 - 2.3 7.9 14.0 3.8 7.1 9.7 1.3 1 0 0 1 1 1 0 SPX domain DUF812 PF05667.6 EDO00212.1 - 2.4 6.5 25.0 0.91 7.9 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) WEMBL PF05701.6 EDO00212.1 - 3 6.2 31.5 5.3 5.3 17.9 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light PilJ PF13675.1 EDO00212.1 - 3 8.1 12.7 2.8 8.2 3.9 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF745 PF05335.8 EDO00212.1 - 3.2 7.2 20.1 0.23 10.9 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4200 PF13863.1 EDO00212.1 - 3.3 7.6 33.1 6.7 6.6 10.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 EDO00212.1 - 3.9 7.3 36.5 0.13 12.1 3.9 5.0 2 2 3 5 5 5 0 Basic region leucine zipper Striatin PF08232.7 EDO00212.1 - 4.2 7.6 24.3 5.5 7.2 11.1 2.2 1 1 1 2 2 2 0 Striatin family CCDC155 PF14662.1 EDO00212.1 - 4.5 6.8 30.3 1.1 8.8 11.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 WXG100 PF06013.7 EDO00212.1 - 5.8 7.0 17.3 8.8 6.4 0.9 3.5 1 1 1 3 3 3 0 Proteins of 100 residues with WXG FUSC PF04632.7 EDO00212.1 - 6.4 5.0 5.6 7.7 4.8 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Uso1_p115_C PF04871.8 EDO00212.1 - 7.2 6.5 26.7 1.3 8.9 2.1 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4201 PF13870.1 EDO00212.1 - 7.6 5.9 25.8 8.2e+02 -0.7 17.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) LRS4 PF10422.4 EDO00212.1 - 9.3 5.5 18.3 19 4.4 12.7 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Nop25 PF09805.4 EDO00213.1 - 8.5e-35 119.8 19.1 1.3e-34 119.2 13.2 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) OmpH PF03938.9 EDO00213.1 - 0.043 13.7 9.3 0.065 13.1 6.5 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-SAP30 PF13866.1 EDO00213.1 - 0.065 12.8 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 SAP30 zinc-finger IncA PF04156.9 EDO00213.1 - 0.52 9.8 4.8 0.67 9.5 3.3 1.2 1 0 0 1 1 1 0 IncA protein SGT1 PF07093.6 EDO00213.1 - 1.9 6.7 12.8 2.1 6.6 8.8 1.0 1 0 0 1 1 1 0 SGT1 protein V-ATPase_G PF03179.10 EDO00213.1 - 7.3 6.9 15.8 0.66 10.3 5.9 2.2 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Med2 PF11214.3 EDO00213.1 - 8 6.5 14.6 0.67 10.0 2.5 2.4 1 1 1 2 2 2 0 Mediator complex subunit 2 ATP-synt_S1 PF05827.7 EDO00214.1 - 2e-59 201.2 0.2 2.3e-59 201.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Fcf1 PF04900.7 EDO00215.1 - 1.4e-41 140.6 0.4 2.3e-41 139.9 0.3 1.3 1 0 0 1 1 1 1 Fcf1 NPP1 PF05630.6 EDO00220.1 - 1e-65 221.3 0.0 1.2e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) AA_permease PF00324.16 EDO00221.1 - 2e-121 405.7 41.7 2.2e-121 405.5 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO00221.1 - 3.4e-32 111.5 45.9 4.1e-32 111.2 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 EDO00222.1 - 2.9e-34 115.6 16.2 2.2e-07 30.4 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EDO00222.1 - 1.3e-22 79.5 0.5 2.3e-22 78.7 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EDO00222.1 - 2.1e-06 26.2 2.1 0.0073 14.4 0.0 3.5 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Colicin_Ia PF11504.3 EDO00222.1 - 0.054 13.4 0.1 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 Colicin Ia MIP PF00230.15 EDO00223.1 - 3.2e-46 157.6 13.7 4.1e-46 157.2 9.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein YibE_F PF07907.6 EDO00223.1 - 0.00031 20.0 5.6 0.012 14.8 0.3 2.2 2 0 0 2 2 2 2 YibE/F-like protein PDR_assoc PF08370.6 EDO00223.1 - 0.17 11.4 2.0 5.2 6.6 0.1 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated UDPGT PF00201.13 EDO00225.1 - 4.1e-07 28.9 0.0 5.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DHHA1 PF02272.14 EDO00225.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 DHHA1 domain HET PF06985.6 EDO00226.1 - 3.7e-36 124.3 1.3 1.1e-35 122.8 0.6 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_M19 PF01244.16 EDO00227.1 - 1.3e-81 274.0 0.0 1e-79 267.7 0.0 2.1 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FCH PF00611.18 EDO00228.1 - 2.2e-14 53.3 0.0 2.2e-13 50.1 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EDO00228.1 - 5.2e-13 48.8 1.0 1.8e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EDO00228.1 - 2.6e-11 43.0 0.0 5e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.27 EDO00229.1 - 4.5e-78 254.5 15.9 8.7e-09 34.9 0.0 11.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EDO00229.1 - 1.9e-47 160.4 0.1 3e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EDO00229.1 - 9.7e-08 30.5 6.2 0.018 13.1 0.0 5.3 3 2 0 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO00229.1 - 4.7e-06 25.6 5.9 0.59 8.8 0.0 5.6 4 1 2 6 6 6 2 Nup133 N terminal like SRP-alpha_N PF04086.8 EDO00229.1 - 0.071 12.4 0.7 0.12 11.7 0.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SAS4 PF15460.1 EDO00230.1 - 0.023 14.5 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Sugar_tr PF00083.19 EDO00232.1 - 3.2e-86 289.6 21.6 3.9e-86 289.4 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO00232.1 - 2.7e-28 98.7 33.3 6.4e-28 97.4 23.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO00232.1 - 1.1e-05 23.8 4.8 1.1e-05 23.8 3.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Dynamitin PF04912.9 EDO00232.1 - 0.27 9.9 0.1 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Dynamitin SF3b1 PF08920.5 EDO00233.1 - 1.6e-42 145.0 0.1 1.6e-42 145.0 0.1 2.6 2 1 1 3 3 3 1 Splicing factor 3B subunit 1 Bac_rhamnosid PF05592.6 EDO00233.1 - 4.5e-21 74.6 0.6 3e-18 65.3 0.0 2.2 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase HEAT_2 PF13646.1 EDO00233.1 - 2.2e-13 50.3 1.9 0.019 15.2 0.0 6.8 5 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EDO00233.1 - 4.8e-10 39.6 1.8 0.3 11.6 0.0 7.3 6 2 2 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EDO00233.1 - 2.4e-09 36.5 6.6 1.7 8.9 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO00233.1 - 0.0003 21.0 0.1 1.4 9.3 0.0 5.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EDO00233.1 - 0.0006 18.2 0.1 0.11 10.8 0.0 2.8 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EDO00233.1 - 0.031 13.6 0.1 8.2 5.7 0.0 3.5 3 0 0 3 3 3 0 NUC173 domain Trehalase PF01204.13 EDO00233.1 - 0.036 12.7 0.2 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Trehalase CLASP_N PF12348.3 EDO00233.1 - 0.073 12.4 0.1 1.6 8.0 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal P34-Arc PF04045.9 EDO00234.1 - 2.3e-102 341.3 0.5 2.8e-102 341.1 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EDO00234.1 - 0.025 13.9 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) DUF1132 PF06575.7 EDO00234.1 - 0.054 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Radical_SAM PF04055.16 EDO00234.1 - 0.098 12.8 1.6 1.7 8.8 0.2 2.7 1 1 2 3 3 3 0 Radical SAM superfamily Hemerythrin PF01814.18 EDO00234.1 - 0.86 9.7 5.9 1.8 8.6 0.9 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain WD40 PF00400.27 EDO00235.1 - 9.4e-71 231.3 18.5 3.1e-08 33.1 0.0 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EDO00235.1 - 9.1e-20 70.6 0.8 1.5e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EDO00235.1 - 0.00012 21.0 1.4 3.5 6.2 0.0 4.9 3 1 2 5 5 5 2 Nup133 N terminal like UTP15_C PF09384.5 EDO00235.1 - 0.0042 16.7 0.3 0.015 15.0 0.1 1.9 2 0 0 2 2 2 1 UTP15 C terminal Nup160 PF11715.3 EDO00235.1 - 0.0071 14.5 0.3 0.43 8.6 0.0 3.2 4 1 0 4 4 4 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO00235.1 - 0.034 13.8 0.0 2.5 7.7 0.0 3.8 5 1 1 6 6 6 0 Eukaryotic translation initiation factor eIF2A APG6 PF04111.7 EDO00236.1 - 0.0093 15.0 3.8 0.0093 15.0 2.6 3.1 2 1 1 3 3 3 1 Autophagy protein Apg6 F-box PF00646.28 EDO00237.1 - 9.3e-08 31.5 0.1 2.8e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDO00237.1 - 2.5e-06 27.0 0.1 6.2e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like HTH_Tnp_Tc5 PF03221.11 EDO00238.1 - 2.7e-16 59.1 0.1 0.00024 20.8 0.0 6.5 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 EDO00238.1 - 1e-12 47.5 0.3 1e-12 47.5 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EDO00238.1 - 2.7e-05 23.6 0.0 9.2e-05 21.9 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EDO00238.1 - 0.84 10.1 25.3 0.018 15.3 2.7 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO00238.1 - 2.7 8.5 28.9 0.03 14.6 2.6 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger Thioredoxin PF00085.15 EDO00244.1 - 4.6e-22 77.6 0.0 7.8e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.14 EDO00244.1 - 6.1e-11 42.5 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Thioredoxin_2 PF13098.1 EDO00244.1 - 7.6e-08 32.5 0.1 2.1e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain ERp29_N PF07912.8 EDO00244.1 - 8.1e-06 25.7 0.2 1.5e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EDO00244.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EDO00244.1 - 0.00076 19.5 0.1 0.007 16.4 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like DUF553 PF04473.7 EDO00244.1 - 0.00076 18.7 0.0 0.0043 16.3 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like domain TraF PF13728.1 EDO00244.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.11 EDO00244.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2232 PF09991.4 EDO00245.1 - 0.015 14.3 4.2 0.016 14.2 2.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) APH PF01636.18 EDO00246.1 - 7.8e-40 137.1 0.0 1.2e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDO00246.1 - 0.00019 20.7 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EDO00246.1 - 0.0013 18.0 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EDO00246.1 - 0.0073 15.3 0.0 0.024 13.6 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDO00246.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EDO00246.1 - 0.015 14.2 0.0 0.21 10.4 0.0 2.2 2 1 0 2 2 2 0 Fructosamine kinase Cas_Cas5d PF09704.5 EDO00247.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) CRA PF06589.6 EDO00247.1 - 0.083 12.2 1.1 0.24 10.7 0.8 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SPATIAL PF15256.1 EDO00247.1 - 5.5 7.0 7.3 1.2 9.2 0.8 2.4 2 0 0 2 2 2 0 SPATIAL AAA_11 PF13086.1 EDO00248.1 - 7.2e-61 205.7 0.1 1.6e-60 204.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDO00248.1 - 1.6e-56 190.8 0.0 5.2e-56 189.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO00248.1 - 6.4e-14 51.4 0.1 3.9e-12 45.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDO00248.1 - 6e-12 45.5 0.0 2.4e-10 40.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDO00248.1 - 8.1e-08 32.3 0.0 2.5e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EDO00248.1 - 1.9e-06 27.5 0.0 0.27 10.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EDO00248.1 - 2.1e-06 26.9 0.2 1.5e-05 24.1 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EDO00248.1 - 9.7e-06 25.0 0.0 2.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EDO00248.1 - 0.00022 21.3 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EDO00248.1 - 0.00028 20.1 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EDO00248.1 - 0.0004 19.9 1.7 0.0014 18.1 0.1 2.6 3 1 0 3 3 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EDO00248.1 - 0.0012 18.3 0.1 0.0045 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 EDO00248.1 - 0.0013 18.2 0.0 0.0068 15.9 0.0 2.1 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) Helicase_RecD PF05127.9 EDO00248.1 - 0.002 17.8 0.0 0.088 12.4 0.0 2.5 1 1 0 1 1 1 1 Helicase IstB_IS21 PF01695.12 EDO00248.1 - 0.0023 17.3 0.0 0.007 15.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Flavi_DEAD PF07652.9 EDO00248.1 - 0.0023 17.6 0.0 0.022 14.5 0.0 2.4 2 0 0 2 2 2 1 Flavivirus DEAD domain 4HB_MCP_1 PF12729.2 EDO00248.1 - 0.0036 16.6 0.1 0.0066 15.8 0.1 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction AAA_16 PF13191.1 EDO00248.1 - 0.0041 17.1 0.0 0.0098 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EDO00248.1 - 0.0069 15.8 0.0 0.026 13.9 0.0 1.8 1 1 1 2 2 2 1 AAA-like domain UvrD_C PF13361.1 EDO00248.1 - 0.0077 15.7 0.3 2.4 7.5 0.0 3.1 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EDO00248.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EDO00248.1 - 0.018 15.2 0.5 0.07 13.3 0.1 2.1 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 EDO00248.1 - 0.019 13.6 0.0 0.036 12.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EDO00248.1 - 0.027 13.9 0.1 0.097 12.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PIF1 PF05970.9 EDO00248.1 - 0.041 12.8 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.9 EDO00248.1 - 0.043 13.5 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDO00248.1 - 0.098 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 EDO00248.1 - 0.13 11.6 0.9 0.64 9.3 0.6 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EDO00248.1 - 0.16 12.2 1.1 0.88 9.8 0.4 2.5 2 1 0 2 2 1 0 AAA domain LEA_2 PF03168.8 EDO00249.1 - 0.95 9.8 6.6 8 6.9 4.6 2.0 1 1 0 1 1 1 0 Late embryogenesis abundant protein DUF2490 PF10677.4 EDO00249.1 - 2.7 7.2 7.8 3.2 6.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) HTH_Tnp_Tc5 PF03221.11 EDO00250.1 - 0.015 15.1 0.0 0.055 13.2 0.0 2.1 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Zn_clus PF00172.13 EDO00251.1 - 0.014 15.2 11.2 0.034 14.0 7.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_7 PF13508.1 EDO00252.1 - 7.8e-13 48.4 0.2 1.4e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO00252.1 - 4.4e-12 45.8 0.1 6.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDO00252.1 - 0.00049 19.9 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO00252.1 - 0.019 14.9 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM PF01423.17 EDO00254.1 - 1.8e-15 56.1 0.1 2.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EDO00254.1 - 0.22 11.9 12.6 0.54 10.7 8.7 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Lipase_3 PF01764.20 EDO00255.1 - 2.3e-16 59.6 0.0 6.4e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Herpes_UL31 PF02718.9 EDO00256.1 - 0.05 12.2 0.1 0.069 11.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL31-like protein G_glu_transpept PF01019.16 EDO00257.1 - 2.1e-107 359.7 5.0 9.8e-87 291.5 0.1 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase DUF1344 PF07076.6 EDO00257.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) AF2331-like PF14556.1 EDO00258.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 AF2331-like VHS PF00790.14 EDO00259.1 - 0.00098 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 VHS domain HEAT_2 PF13646.1 EDO00259.1 - 0.002 18.3 0.0 0.0073 16.5 0.0 1.9 1 1 1 2 2 2 1 HEAT repeats Glyco_hydro_3 PF00933.16 EDO00261.1 - 0.00018 20.5 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain NmrA PF05368.8 EDO00262.1 - 4.7e-23 81.6 0.0 2e-22 79.6 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDO00262.1 - 1.3e-08 35.0 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDO00262.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDO00262.1 - 0.0098 15.8 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 TrkA-N domain DUF2784 PF10861.3 EDO00262.1 - 0.0098 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) 3Beta_HSD PF01073.14 EDO00262.1 - 0.01 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SPC12 PF06645.8 EDO00262.1 - 0.031 14.0 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Semialdhyde_dh PF01118.19 EDO00262.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FG-GAP PF01839.18 EDO00263.1 - 1.4e-08 34.1 2.1 0.016 14.8 0.1 3.6 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 EDO00263.1 - 5.2e-07 29.9 12.7 0.0014 18.9 0.2 4.7 1 1 3 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EDO00263.1 - 4.3e-06 26.2 0.8 0.14 11.5 0.0 3.2 3 0 0 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region VRR_NUC PF08774.6 EDO00263.1 - 0.0011 18.9 0.0 2 8.4 0.0 3.1 1 1 2 3 3 3 1 VRR-NUC domain DUF756 PF05506.7 EDO00263.1 - 0.0036 17.7 7.2 11 6.5 0.0 4.9 2 1 3 5 5 5 1 Domain of unknown function (DUF756) Cleaved_Adhesin PF07675.6 EDO00263.1 - 0.0084 15.7 1.7 2.4 7.7 0.0 2.6 2 1 0 2 2 2 2 Cleaved Adhesin Domain EF-hand_6 PF13405.1 EDO00263.1 - 0.015 15.1 0.6 16 5.6 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EDO00263.1 - 0.04 13.2 2.0 13 5.3 0.0 3.3 3 0 0 3 3 3 0 EF hand FaeA PF04703.7 EDO00263.1 - 0.053 13.6 1.2 43 4.3 0.0 4.0 4 0 0 4 4 4 0 FaeA-like protein DUF4019 PF13211.1 EDO00263.1 - 0.066 13.4 1.4 7 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) FtsA PF14450.1 EDO00263.1 - 0.43 10.4 2.3 17 5.2 0.0 3.1 3 0 0 3 3 3 0 Cell division protein FtsA EF-hand_5 PF13202.1 EDO00263.1 - 0.8 9.1 5.0 25 4.4 0.0 3.3 3 0 0 3 3 3 0 EF hand Endotoxin_C PF03944.9 EDO00263.1 - 2.6 8.1 5.9 12 5.9 0.1 3.0 1 1 2 3 3 3 0 delta endotoxin RibD_C PF01872.12 EDO00264.1 - 1.1e-33 116.5 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DUF1641 PF07849.6 EDO00264.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) SLS PF14611.1 EDO00266.1 - 1.1e-07 31.5 0.1 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.14 EDO00267.1 - 6.8e-41 139.7 0.2 8.9e-41 139.3 0.1 1.2 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.6 EDO00268.1 - 4.1e-38 129.0 0.0 4.6e-38 128.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RPAP2_Rtr1 PF04181.8 EDO00269.1 - 2 8.5 13.2 1.6e+03 -0.8 9.2 3.0 1 1 0 1 1 1 0 Rtr1/RPAP2 family HTH_psq PF05225.11 EDO00270.1 - 5.9e-09 35.3 0.0 8.2e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDO00270.1 - 0.0049 16.6 0.6 0.078 12.8 0.1 2.5 2 1 0 2 2 2 1 NUMOD1 domain Sec34 PF04136.10 EDO00270.1 - 0.075 12.7 0.1 4.3 7.0 0.1 2.0 1 1 1 2 2 2 0 Sec34-like family HTH_37 PF13744.1 EDO00270.1 - 0.12 12.2 0.6 0.23 11.3 0.4 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Fis1_TPR_C PF14853.1 EDO00271.1 - 0.056 13.3 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.20 EDO00273.1 - 3.8e-47 160.6 0.0 5.1e-44 150.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00273.1 - 6.6e-31 107.3 0.0 3.7e-30 104.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO00273.1 - 0.0043 16.0 0.0 0.0064 15.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EDO00273.1 - 0.007 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EDO00273.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDO00273.1 - 0.08 11.7 0.1 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF902 PF06001.8 EDO00274.1 - 4.8 7.4 7.3 13 6.0 0.1 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF902) Mem_trans PF03547.13 EDO00275.1 - 1.8e-34 118.7 6.9 2e-33 115.2 4.8 2.0 1 1 0 1 1 1 1 Membrane transport protein COesterase PF00135.23 EDO00276.1 - 1.3e-92 311.2 0.0 1.6e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDO00276.1 - 0.00028 20.5 0.3 0.0017 17.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Choline_kinase PF01633.15 EDO00279.1 - 2.6e-62 210.1 0.0 2.9e-61 206.7 0.0 2.5 3 0 0 3 3 3 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EDO00279.1 - 1.4e-23 82.0 0.2 5.1e-23 80.2 0.0 2.1 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 EDO00279.1 - 5.3e-06 26.3 1.8 9.6e-06 25.4 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSP90 PF00183.13 EDO00281.1 - 0.011 14.1 15.7 0.014 13.8 10.9 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF3449 PF11931.3 EDO00281.1 - 0.015 14.8 1.8 0.015 14.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Trypan_PARP PF05887.6 EDO00281.1 - 0.043 13.6 12.2 0.052 13.3 8.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 EDO00281.1 - 0.09 12.1 11.2 0.1 11.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 EDO00281.1 - 0.1 11.8 18.6 0.12 11.5 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EDO00281.1 - 0.11 10.5 16.2 0.12 10.3 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EDO00281.1 - 0.14 9.8 0.7 0.15 9.7 0.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF913 PF06025.7 EDO00281.1 - 0.14 10.8 0.5 0.15 10.7 0.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.9 EDO00281.1 - 0.18 11.7 1.2 0.21 11.5 0.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 BUD22 PF09073.5 EDO00281.1 - 0.2 10.6 15.3 0.22 10.5 10.6 1.0 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 EDO00281.1 - 0.4 10.3 17.9 0.51 10.0 12.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TraH_2 PF06871.6 EDO00281.1 - 0.41 10.0 2.1 0.46 9.9 1.5 1.1 1 0 0 1 1 1 0 TraH_2 SGT1 PF07093.6 EDO00281.1 - 0.41 8.9 10.4 0.46 8.8 7.2 1.0 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 EDO00281.1 - 0.53 8.7 24.1 0.59 8.5 16.7 1.0 1 0 0 1 1 1 0 Daxx Family Mpp10 PF04006.7 EDO00281.1 - 0.7 8.1 18.1 0.7 8.1 12.5 1.0 1 0 0 1 1 1 0 Mpp10 protein IFT57 PF10498.4 EDO00281.1 - 0.82 8.3 10.5 0.89 8.2 7.3 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Paf1 PF03985.8 EDO00281.1 - 0.93 8.1 16.3 1.1 7.9 11.3 1.0 1 0 0 1 1 1 0 Paf1 DUF4484 PF14831.1 EDO00281.1 - 0.93 9.5 9.1 1.2 9.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Nop25 PF09805.4 EDO00281.1 - 1.2 9.1 14.9 1.5 8.9 10.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Prog_receptor PF02161.10 EDO00281.1 - 1.3 7.7 5.3 1.3 7.7 3.7 1.0 1 0 0 1 1 1 0 Progesterone receptor XAP5 PF04921.9 EDO00281.1 - 1.3 8.5 8.7 1.5 8.3 6.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Polyoma_lg_T_C PF06431.6 EDO00281.1 - 1.5 7.3 5.0 1.4 7.4 3.5 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Astro_capsid PF03115.9 EDO00281.1 - 1.6 6.8 9.7 1.6 6.8 6.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor VID27 PF08553.5 EDO00281.1 - 1.8 6.7 15.3 1.8 6.6 10.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 EDO00281.1 - 2 7.3 16.4 2.3 7.1 11.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Conotoxin PF02950.12 EDO00281.1 - 2.6 8.8 6.8 5.1 7.9 4.7 1.5 1 1 0 1 1 1 0 Conotoxin Rhabdo_ncap PF00945.13 EDO00281.1 - 2.7 6.4 6.4 2.8 6.4 4.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2457 PF10446.4 EDO00281.1 - 3.3 6.3 36.2 4.1 6.0 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 EDO00281.1 - 3.4 7.5 25.9 3.6 7.4 17.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.5 EDO00281.1 - 3.5 6.7 10.7 4.1 6.5 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.6 EDO00281.1 - 4.6 4.9 13.0 5.8 4.6 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.3 EDO00281.1 - 4.9 6.0 10.1 5.2 5.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YL1 PF05764.8 EDO00281.1 - 5.5 6.5 23.6 6.1 6.3 16.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Med17 PF10156.4 EDO00281.1 - 6.2 4.9 7.6 6.1 4.9 5.2 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Tim54 PF11711.3 EDO00281.1 - 6.4 5.2 6.7 7.4 5.0 4.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 EDO00281.1 - 7.7 6.5 6.5 10 6.1 4.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 EDO00281.1 - 8 6.2 9.2 9.4 6.0 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EDO00281.1 - 8 6.4 12.2 10 6.1 8.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 EDO00281.1 - 8.5 5.5 24.1 9.4 5.4 16.7 1.0 1 0 0 1 1 1 0 SDA1 TEX19 PF15553.1 EDO00281.1 - 8.8 6.1 8.4 12 5.6 5.8 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 SspB PF04386.8 EDO00281.1 - 9.9 5.7 10.9 12 5.4 7.6 1.1 1 0 0 1 1 1 0 Stringent starvation protein B HNH_3 PF13392.1 EDO00282.1 - 0.011 15.0 0.1 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 HNH endonuclease Reo_sigmaC PF04582.7 EDO00283.1 - 1e-12 47.8 105.2 0.00028 20.1 5.1 9.2 1 1 9 11 11 11 11 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EDO00283.1 - 5.4e-10 39.2 66.0 0.078 12.8 3.9 11.2 1 1 9 10 10 10 7 Baculovirus polyhedron envelope protein, PEP, C terminus Tubulin-binding PF00418.14 EDO00283.1 - 2.5e-06 27.0 24.1 13 5.6 0.0 12.7 16 0 0 16 16 16 0 Tau and MAP protein, tubulin-binding repeat DUF3829 PF12889.2 EDO00283.1 - 2.4e-05 23.6 53.8 0.15 11.2 0.0 10.5 2 1 7 10 10 10 5 Protein of unknown function (DUF3829) TarH PF02203.10 EDO00283.1 - 2.5e-05 24.1 5.6 2.7 7.8 0.1 5.1 2 2 2 4 4 4 2 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.2 EDO00283.1 - 0.00041 19.7 38.8 0.0028 17.0 0.1 8.7 4 4 5 10 10 10 2 Four helix bundle sensory module for signal transduction Cytochrom_B562 PF07361.6 EDO00283.1 - 0.27 11.6 42.6 1.9 8.9 0.4 9.8 4 2 5 11 11 11 0 Cytochrome b562 DNA_repr_REX1B PF14966.1 EDO00283.1 - 0.89 9.9 9.0 0.69 10.3 0.4 4.8 4 0 0 4 4 4 0 DNA repair REX1-B FlaC_arch PF05377.6 EDO00283.1 - 0.95 9.4 118.0 3.3 7.6 0.5 24.7 16 4 9 25 25 25 0 Flagella accessory protein C (FlaC) Defensin_propep PF00879.13 EDO00283.1 - 1.3 9.0 13.2 1.6e+02 2.3 0.0 7.7 10 0 0 10 10 10 0 Defensin propeptide Cob_adeno_trans PF01923.13 EDO00283.1 - 5.7 6.7 35.6 12 5.6 0.1 9.2 1 1 7 11 11 11 0 Cobalamin adenosyltransferase MerR-DNA-bind PF09278.6 EDO00283.1 - 6.9 7.1 6.6 22 5.5 0.0 5.3 6 1 2 8 8 7 0 MerR, DNA binding CAMP_factor PF07373.6 EDO00283.1 - 9.2 5.6 96.9 0.22 11.0 6.1 9.7 1 1 9 10 10 10 0 CAMP factor (Cfa) Allexi_40kDa PF05549.6 EDO00283.1 - 9.7 5.3 71.8 0.36 10.0 0.8 10.4 2 2 8 11 11 11 0 Allexivirus 40kDa protein UBA_4 PF14555.1 EDO00284.1 - 7.7e-11 41.3 0.2 1.6e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EDO00284.1 - 9.2e-10 38.4 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain MAP7 PF05672.6 EDO00284.1 - 0.00037 19.9 15.5 0.0007 19.0 10.7 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DUF4207 PF13904.1 EDO00284.1 - 0.002 17.5 8.6 0.0032 16.8 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DDHD PF02862.12 EDO00284.1 - 1.5 8.5 4.5 3 7.5 3.1 1.5 1 0 0 1 1 1 0 DDHD domain DUF1003 PF06210.6 EDO00284.1 - 2.1 8.2 4.3 8.7 6.3 3.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Pkinase PF00069.20 EDO00286.1 - 0.037 13.1 0.1 0.078 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein kinase domain zf-CCCH PF00642.19 EDO00286.1 - 0.17 11.6 0.6 0.34 10.6 0.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC45 PF02724.9 EDO00286.1 - 0.46 8.4 4.0 0.74 7.7 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 EDO00286.1 - 1.3 8.5 5.8 0.46 10.0 1.4 2.0 2 0 0 2 2 2 0 IncA protein Nucleoplasmin PF03066.10 EDO00286.1 - 2.5 7.5 9.5 4.2 6.8 6.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4246 PF14033.1 EDO00287.1 - 7.3e-140 466.9 2.0 9.2e-140 466.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Nop14 PF04147.7 EDO00287.1 - 0.7 7.7 9.6 0.98 7.2 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EDO00287.1 - 3.7 5.9 13.0 9.7 4.5 5.4 2.1 2 0 0 2 2 2 0 Daxx Family Glyco_hydro_61 PF03443.9 EDO00288.1 - 1.2e-81 273.6 0.3 1.6e-81 273.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4597 PF15366.1 EDO00288.1 - 0.015 14.8 0.9 0.04 13.5 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Glyco_hydro_61 PF03443.9 EDO00290.1 - 6e-75 251.8 0.4 6e-75 251.8 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CSD PF00313.17 EDO00290.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Macoilin PF09726.4 EDO00290.1 - 8.3 4.5 8.9 11 4.1 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein p450 PF00067.17 EDO00293.1 - 1.2e-41 142.7 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EDO00295.1 - 1.9e-43 148.5 44.7 3.6e-43 147.6 31.0 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF946 PF06101.6 EDO00295.1 - 0.12 10.3 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) p450 PF00067.17 EDO00296.1 - 2.3e-26 92.3 0.0 1e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 EDO00298.1 - 1.9e-33 115.7 0.2 3.2e-33 114.9 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_J PF04911.7 EDO00298.1 - 0.1 12.0 0.0 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 ATP synthase j chain PRP38_assoc PF12871.2 EDO00301.1 - 0.0013 19.2 22.7 0.0013 19.2 15.7 2.8 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TraT PF05818.7 EDO00301.1 - 0.037 13.4 0.3 0.084 12.2 0.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Trypan_PARP PF05887.6 EDO00301.1 - 3.1 7.6 9.1 8 6.2 2.4 2.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Atrophin-1 PF03154.10 EDO00301.1 - 6.7 4.7 23.1 12 3.8 16.0 1.4 1 0 0 1 1 1 0 Atrophin-1 family Acetyltransf_1 PF00583.19 EDO00302.1 - 2.4e-07 30.6 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO00302.1 - 0.003 17.6 0.0 0.0047 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO00302.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_A22B PF04258.8 EDO00303.1 - 9.6e-56 189.4 0.0 1.9e-55 188.4 0.0 1.5 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EDO00303.1 - 0.018 14.1 15.3 0.0085 15.2 6.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1119) Pro_isomerase PF00160.16 EDO00304.1 - 3.8e-22 79.1 0.0 4.7e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NT-C2 PF10358.4 EDO00305.1 - 1.2e-32 112.3 0.0 1.9e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DHquinase_II PF01220.14 EDO00307.1 - 8.4e-59 196.8 0.0 9.5e-59 196.7 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II DUF1183 PF06682.7 EDO00310.1 - 0.009 15.6 0.2 0.009 15.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) IBR PF01485.16 EDO00311.1 - 2.1e-15 56.3 24.7 3e-11 43.0 3.0 3.8 3 1 0 3 3 3 2 IBR domain Chitin_bind_1 PF00187.14 EDO00314.1 - 7.6e-21 73.8 84.4 6.8e-08 32.3 9.7 5.3 3 1 2 5 5 5 4 Chitin recognition protein CBM_1 PF00734.13 EDO00314.1 - 8e-11 41.4 0.9 8e-11 41.4 0.6 7.3 7 2 1 8 8 8 1 Fungal cellulose binding domain His_Phos_1 PF00300.17 EDO00317.1 - 5e-29 101.4 0.1 6.1e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ALO PF04030.9 EDO00318.1 - 1.4e-90 303.3 1.4 1.9e-90 303.0 1.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EDO00318.1 - 1.2e-27 96.0 0.0 2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Mucin PF01456.12 EDO00319.1 - 4.1 7.1 17.8 1 9.1 4.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF336 PF03928.9 EDO00320.1 - 1.9e-15 56.8 0.0 2e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Ribosomal_L24e PF01246.15 EDO00324.1 - 3.7e-31 106.7 0.3 3.7e-31 106.7 0.2 1.8 2 1 0 2 2 2 1 Ribosomal protein L24e AdoMet_MTase PF07757.8 EDO00325.1 - 4.3e-40 136.3 0.0 6.3e-40 135.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EDO00325.1 - 0.00045 19.9 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO00325.1 - 0.048 13.3 0.2 0.61 9.7 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain NAC PF01849.13 EDO00329.1 - 8.6e-21 73.2 0.1 1.6e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain NOGCT PF08155.6 EDO00329.1 - 0.022 14.4 0.6 0.046 13.4 0.4 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain DUF3477 PF11963.3 EDO00330.1 - 0.029 13.3 0.1 0.039 12.9 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3477) HEAT_EZ PF13513.1 EDO00334.1 - 6.1e-13 48.8 13.4 4.9e-07 30.0 0.0 8.0 8 1 2 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.1 EDO00334.1 - 1.2e-12 47.8 15.4 5.5e-06 26.5 0.0 6.8 3 2 5 8 8 8 5 HEAT repeats HEAT PF02985.17 EDO00334.1 - 1.8e-12 46.2 7.0 0.00023 20.9 0.0 9.0 10 0 0 10 10 10 2 HEAT repeat IBN_N PF03810.14 EDO00334.1 - 1.5e-10 40.8 2.3 7.6e-09 35.3 0.4 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 EDO00334.1 - 8.2e-05 22.2 0.9 3.4 7.6 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EDO00334.1 - 0.0004 20.3 0.8 1.2 9.0 0.0 4.6 4 1 0 4 4 4 1 Exportin 1-like protein CLASP_N PF12348.3 EDO00334.1 - 0.00053 19.4 0.4 13 5.0 0.0 5.4 4 1 2 6 6 6 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EDO00334.1 - 0.00085 19.6 1.0 25 5.3 0.1 5.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EDO00334.1 - 0.01 16.2 2.1 12 6.6 0.0 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 EDO00334.1 - 0.025 14.4 0.2 15 5.3 0.0 4.2 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HMGL-like PF00682.14 EDO00335.1 - 8.4e-64 215.4 0.0 1.4e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EDO00335.1 - 5.6e-26 90.9 0.0 9.3e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.14 EDO00336.1 - 1.3e-21 76.9 6.1 1.3e-21 76.9 4.2 3.0 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDO00336.1 - 7.7e-18 64.8 0.0 5.2e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDO00336.1 - 3.6e-13 49.2 0.0 9.7e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain DUF1690 PF07956.6 EDO00338.1 - 3.9e-25 88.4 9.6 5e-25 88.1 6.7 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.1 EDO00338.1 - 0.0073 15.7 5.7 0.0073 15.7 3.9 2.0 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CHCH PF06747.8 EDO00338.1 - 0.041 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 CHCH domain AAA_13 PF13166.1 EDO00338.1 - 0.1 11.0 5.1 0.14 10.5 3.5 1.2 1 0 0 1 1 1 0 AAA domain Erp_C PF06780.6 EDO00338.1 - 0.15 11.9 5.4 0.2 11.4 3.7 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Mnd1 PF03962.10 EDO00338.1 - 1 9.0 10.2 1.8 8.1 7.0 1.5 1 1 0 1 1 1 0 Mnd1 family Tox-REase-2 PF15646.1 EDO00338.1 - 1.2 8.9 4.6 1.5 8.7 0.7 2.1 1 1 0 2 2 2 0 Restriction endonuclease fold toxin 2 HSCB_C PF07743.8 EDO00338.1 - 1.3 9.5 8.5 3.9 7.9 0.4 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF2458 PF10454.4 EDO00338.1 - 1.4 8.8 6.0 1.5 8.6 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Rotamase PF00639.16 EDO00338.1 - 1.5 9.6 5.6 1.4 9.7 2.0 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain OmpH PF03938.9 EDO00338.1 - 1.6 8.6 6.2 2.1 8.2 4.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EDO00338.1 - 2.1 8.5 8.3 11 6.2 5.4 2.2 1 1 0 1 1 1 0 Syntaxin DUF1789 PF08748.6 EDO00338.1 - 2.5 8.2 5.4 1.2 9.2 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) TMF_TATA_bd PF12325.3 EDO00338.1 - 3.8 7.2 12.5 0.68 9.6 3.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PP2C_C PF07830.8 EDO00338.1 - 4.3 7.5 5.3 7.6 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1843 PF08898.5 EDO00338.1 - 5.2 7.1 8.7 2.9 8.0 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) V_ATPase_I PF01496.14 EDO00338.1 - 7.5 4.2 5.8 8.7 4.0 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3391 PF11871.3 EDO00338.1 - 9.6 6.4 13.4 2.7 8.2 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) TYW3 PF02676.9 EDO00339.1 - 1.8e-34 118.7 0.0 5.1e-28 97.6 0.0 2.0 1 1 1 2 2 2 2 Methyltransferase TYW3 Pkinase PF00069.20 EDO00342.1 - 2.3e-08 33.5 0.0 4.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00342.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO00342.1 - 0.015 15.0 0.2 0.047 13.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDO00342.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CRF PF00473.12 EDO00344.1 - 0.038 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family EMP70 PF02990.11 EDO00346.1 - 9.8e-195 647.9 4.5 1.1e-194 647.7 3.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EDO00346.1 - 0.0062 16.6 0.0 0.0062 16.6 0.0 3.8 3 1 0 3 3 3 1 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EDO00346.1 - 1.5 8.0 5.6 0.48 9.6 1.6 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 EDO00347.1 - 4.4e-16 58.8 1.8 9.5e-16 57.7 1.2 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF3069 PF11269.3 EDO00347.1 - 0.02 14.9 0.3 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) DDE_1 PF03184.14 EDO00352.1 - 4.8e-48 163.1 0.0 1.1e-47 161.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO00352.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO00352.1 - 3.6e-07 29.9 2.9 3.8e-07 29.8 0.0 2.7 4 0 0 4 4 4 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO00352.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO00352.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Sulfate_transp PF00916.15 EDO00353.1 - 8.5e-77 257.8 13.9 1.5e-76 257.0 9.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDO00353.1 - 1.3e-30 104.9 3.7 1.3e-30 104.9 2.6 3.7 3 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDO00353.1 - 1.2e-08 34.4 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain RabGAP-TBC PF00566.13 EDO00355.1 - 7.9e-31 107.1 0.0 5.6e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TAP_C PF03943.8 EDO00356.1 - 8.9e-13 47.4 0.5 1.7e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EDO00356.1 - 4.7e-07 29.2 11.9 4.7e-05 22.8 1.9 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EDO00356.1 - 0.0004 20.7 0.0 0.0014 18.9 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 EDO00356.1 - 0.0019 17.8 2.7 0.0019 17.8 1.8 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 EDO00356.1 - 0.0039 17.1 7.3 0.95 9.9 0.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EDO00356.1 - 0.26 11.4 10.5 4 7.8 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 EDO00356.1 - 0.37 10.9 8.7 3.8 7.8 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeat COPIIcoated_ERV PF07970.7 EDO00358.1 - 6.9e-54 182.8 0.0 1e-51 175.6 0.0 2.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDO00358.1 - 1.2e-16 60.4 0.4 1.8e-15 56.6 0.1 2.2 1 1 1 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 EDO00359.1 - 3e-13 49.9 5.7 0.0088 16.6 0.0 4.5 4 0 0 4 4 4 4 Sel1 repeat CENP-K PF11802.3 EDO00360.1 - 0.0094 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Centromere-associated protein K PBP_sp32 PF07222.7 EDO00360.1 - 0.095 11.8 0.5 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GYD PF08734.6 EDO00361.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 GYD domain DUF3491 PF11996.3 EDO00361.1 - 0.1 10.1 0.0 0.11 9.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) KH_1 PF00013.24 EDO00363.1 - 2e-38 129.8 2.4 3.4e-16 58.6 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDO00363.1 - 7.4e-30 102.0 7.8 4.3e-12 45.3 1.4 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDO00363.1 - 4.2e-12 45.4 3.0 0.0046 16.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDO00363.1 - 0.0054 16.3 0.6 4.6 6.9 0.1 3.2 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 EDO00363.1 - 0.0092 15.7 6.6 0.95 9.3 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain ABM PF03992.11 EDO00364.1 - 4e-06 26.7 0.2 0.042 13.8 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase RNase_H PF00075.19 EDO00365.1 - 1.3e-15 57.8 0.0 2.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF993 PF06187.6 EDO00365.1 - 0.02 13.4 0.0 0.036 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Glyco_hydro_47 PF01532.15 EDO00366.1 - 3.4e-167 556.6 0.0 3.9e-167 556.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 EDO00366.1 - 0.071 12.1 0.0 2.7 6.8 0.0 2.8 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF3129 PF11327.3 EDO00367.1 - 3.8e-34 118.0 11.9 3.8e-34 118.0 8.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) Bac_luciferase PF00296.15 EDO00368.1 - 3.3e-59 200.5 0.0 5.1e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.1 EDO00369.1 - 3.1e-21 76.3 0.0 8.2e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO00369.1 - 1.8e-16 59.5 0.3 2.7e-15 55.6 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDO00369.1 - 3.3e-08 33.4 0.0 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO00369.1 - 3.5e-06 27.0 0.0 2.2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO00369.1 - 1.9e-05 23.7 0.0 0.00023 20.2 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDO00369.1 - 0.0001 22.1 0.1 0.012 15.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EDO00369.1 - 0.00016 20.7 0.0 0.48 9.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EDO00369.1 - 0.011 14.8 0.1 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EDO00369.1 - 0.083 12.4 0.1 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EDO00369.1 - 0.19 10.1 0.7 2.5 6.4 0.5 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EDO00369.1 - 0.3 9.8 1.6 2.7 6.7 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EDO00370.1 - 2.9e-11 42.6 28.5 2.9e-11 42.6 19.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDO00370.1 - 6.1e-08 32.3 2.9 1.4e-07 31.1 2.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EDO00370.1 - 8e-06 24.6 3.6 8e-06 24.6 2.5 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter PUCC PF03209.10 EDO00370.1 - 0.00086 18.1 2.4 0.00086 18.1 1.7 2.0 3 0 0 3 3 3 1 PUCC protein Nop14 PF04147.7 EDO00371.1 - 0.043 11.7 0.3 0.044 11.7 0.2 1.0 1 0 0 1 1 1 0 Nop14-like family Polysacc_synt_3 PF13440.1 EDO00374.1 - 0.045 13.2 7.6 0.014 14.9 3.2 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EDO00374.1 - 0.073 11.7 12.2 0.24 10.0 8.5 1.8 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3742 PF12553.3 EDO00376.1 - 0.13 12.6 0.7 0.19 12.2 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) ThiC-associated PF13667.1 EDO00377.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 ThiC-associated domain DUF202 PF02656.10 EDO00379.1 - 8.8e-27 93.1 0.9 2.9e-26 91.4 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Ni_hydr_CYTB PF01292.15 EDO00379.1 - 0.12 11.7 0.9 0.17 11.2 0.6 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4355 PF14265.1 EDO00380.1 - 0.094 12.6 4.3 0.032 14.1 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3465 PF11948.3 EDO00380.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) SpecificRecomb PF10136.4 EDO00382.1 - 0.04 11.9 0.6 0.056 11.4 0.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase Ferritin PF00210.19 EDO00384.1 - 0.029 14.1 2.5 0.98 9.1 0.2 2.2 1 1 1 2 2 2 0 Ferritin-like domain OEP PF02321.13 EDO00384.1 - 0.25 10.9 3.0 5.9 6.4 1.3 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein LemA PF04011.7 EDO00385.1 - 0.065 12.3 0.2 0.21 10.6 0.0 1.8 1 1 1 2 2 2 0 LemA family Nucleoporin_FG PF13634.1 EDO00386.1 - 7.5e-12 45.4 37.0 7.5e-12 45.4 25.6 7.6 5 1 3 8 8 8 3 Nucleoporin FG repeat region WD40 PF00400.27 EDO00386.1 - 0.12 12.3 0.1 0.52 10.2 0.1 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat Proteasome PF00227.21 EDO00387.1 - 1.8e-46 157.8 0.1 2.2e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EDO00387.1 - 1.8e-13 49.4 1.3 3.7e-13 48.4 0.9 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal TauD PF02668.11 EDO00389.1 - 6.6e-26 91.5 0.0 8.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_26 PF13659.1 EDO00391.1 - 5.3e-13 49.0 0.0 7.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO00391.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EDO00392.1 - 1.4e-15 56.5 0.0 1.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO00392.1 - 0.00044 20.1 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EDO00392.1 - 0.033 14.4 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Pkr1 PF08636.5 EDO00393.1 - 1.2e-34 118.1 6.7 1.5e-34 117.8 4.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.1 EDO00393.1 - 0.02 14.2 0.1 0.026 13.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1183 PF06682.7 EDO00393.1 - 0.068 12.7 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Sugar_tr PF00083.19 EDO00394.1 - 3.9e-35 121.3 25.7 1.5e-14 53.4 7.3 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EDO00394.1 - 5.5e-07 28.6 7.1 5.5e-07 28.6 4.9 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily MmgE_PrpD PF03972.9 EDO00395.1 - 0.00064 18.0 0.0 0.00067 17.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MBOAT_2 PF13813.1 EDO00397.1 - 1.4e-16 60.3 1.3 4.2e-16 58.7 0.1 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family SNF2_N PF00176.18 EDO00398.1 - 1.2e-74 250.8 0.8 2.2e-74 249.9 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO00398.1 - 8.9e-15 54.3 0.0 3.7e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EDO00398.1 - 0.029 14.1 8.0 0.046 13.4 4.4 2.4 1 1 0 1 1 1 0 HSA CobD_Cbib PF03186.8 EDO00398.1 - 0.99 8.4 1.6 14 4.6 0.0 2.2 2 0 0 2 2 2 0 CobD/Cbib protein NDUF_B8 PF05821.6 EDO00399.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2205 PF10224.4 EDO00401.1 - 6.9e-31 105.6 1.5 1.1e-30 105.0 1.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) SapC PF07277.6 EDO00401.1 - 0.0055 16.0 0.1 0.0068 15.7 0.1 1.2 1 0 0 1 1 1 1 SapC Terpene_synth_C PF03936.11 EDO00401.1 - 0.017 14.3 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain TACC PF05010.9 EDO00401.1 - 0.024 14.3 1.4 0.034 13.9 1.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF908 PF06012.7 EDO00403.1 - 0.0061 15.9 6.8 0.0077 15.5 4.7 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Nab6_mRNP_bdg PF10567.4 EDO00403.1 - 0.029 13.3 5.7 0.036 13.0 3.9 1.1 1 0 0 1 1 1 0 RNA-recognition motif Ctr PF04145.10 EDO00403.1 - 0.17 11.9 2.3 0.29 11.1 1.6 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Zip PF02535.17 EDO00403.1 - 0.25 10.3 3.1 0.33 9.9 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.6 EDO00403.1 - 0.49 10.0 5.0 0.77 9.3 3.5 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4407 PF14362.1 EDO00403.1 - 0.5 9.2 5.3 0.72 8.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G0-G1_switch_2 PF15103.1 EDO00403.1 - 0.8 9.9 5.2 1.3 9.2 3.6 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Band_3_cyto PF07565.8 EDO00403.1 - 1.2 8.6 7.7 1.6 8.1 5.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FliP PF00813.15 EDO00403.1 - 2.1 7.9 4.5 3 7.5 3.1 1.1 1 0 0 1 1 1 0 FliP family TMEM169 PF15052.1 EDO00404.1 - 0.011 15.6 0.3 0.011 15.6 0.2 1.0 1 0 0 1 1 1 0 TMEM169 protein family TRAPPC10 PF12584.3 EDO00406.1 - 1.7e-31 108.7 0.0 3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EDO00406.1 - 0.00081 18.9 0.9 0.0017 17.9 0.6 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 AA_permease PF00324.16 EDO00407.1 - 2.9e-97 325.9 44.0 2.4e-94 316.3 28.2 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDO00407.1 - 2.2e-23 82.5 36.9 8.4e-23 80.5 16.6 2.2 1 1 1 2 2 2 2 Amino acid permease DUF1772 PF08592.6 EDO00407.1 - 0.37 10.5 12.3 0.39 10.4 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DnaJ PF00226.26 EDO00408.1 - 1.8e-26 91.6 1.8 3.4e-26 90.7 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO00408.1 - 1.9e-22 78.9 0.1 1.8e-18 66.2 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO00408.1 - 1.2e-13 50.8 18.6 1.2e-13 50.8 12.9 1.7 2 0 0 2 2 2 1 DnaJ central domain zf-RING_3 PF14369.1 EDO00408.1 - 0.048 13.6 0.4 14 5.7 0.0 2.9 2 0 0 2 2 2 0 zinc-finger HypA PF01155.14 EDO00408.1 - 0.071 12.7 9.7 0.23 11.1 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EDO00408.1 - 0.34 10.7 5.9 4.6 7.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 EDO00408.1 - 1.4 8.7 6.4 12 5.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.2 EDO00408.1 - 5.8 6.8 9.4 8.4 6.2 1.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain dCMP_cyt_deam_1 PF00383.17 EDO00409.1 - 7.9e-11 41.5 0.0 1.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region URO-D PF01208.12 EDO00410.1 - 9.6e-74 248.3 0.0 1.2e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PPR_3 PF13812.1 EDO00411.1 - 0.085 13.1 0.4 2 8.9 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain WD40 PF00400.27 EDO00412.1 - 7.6e-06 25.6 0.1 1 9.3 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Geminin PF07412.7 EDO00412.1 - 0.017 14.7 3.3 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 Geminin CPSF_A PF03178.10 EDO00412.1 - 0.05 12.6 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 CPSF A subunit region Ribosomal_L10 PF00466.15 EDO00413.1 - 2.4e-25 88.3 0.0 4.9e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EDO00413.1 - 4.2e-13 49.5 7.4 8e-13 48.6 3.0 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 EDO00414.1 - 2e-81 272.8 0.0 3.4e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO00414.1 - 2.6e-20 73.0 1.7 5e-20 72.1 1.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO00414.1 - 1.7e-19 69.9 0.0 5e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EDO00414.1 - 9e-09 35.5 0.1 8.7e-08 32.3 0.0 2.5 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EDO00414.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EDO00414.1 - 0.019 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EDO00414.1 - 0.085 12.5 0.0 56 3.4 0.0 3.4 3 0 0 3 3 3 0 NTPase Flavodoxin_1 PF00258.20 EDO00415.1 - 4.5e-09 36.4 0.0 7.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EDO00415.1 - 3.7e-08 33.0 0.0 5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EDO00415.1 - 4.6e-06 26.2 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EDO00415.1 - 0.049 13.6 0.0 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain zf-HC5HC2H_2 PF13832.1 EDO00416.1 - 1.4e-18 66.8 1.5 1.4e-18 66.8 1.0 4.1 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO00416.1 - 1.1e-16 60.7 2.8 1.1e-16 60.7 1.9 4.2 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 EDO00416.1 - 5.5e-15 55.1 0.1 1.2e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EDO00416.1 - 1.7e-14 53.2 50.7 1.4e-07 31.0 3.9 6.4 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EDO00416.1 - 5e-10 38.5 6.6 5e-10 38.5 4.6 5.6 8 0 0 8 8 8 2 PHD-finger Prok-RING_1 PF14446.1 EDO00416.1 - 2.6e-06 27.0 33.1 0.061 13.0 3.0 4.5 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 C1_1 PF00130.17 EDO00416.1 - 0.0019 17.8 3.1 0.0019 17.8 2.2 5.7 6 1 0 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.24 EDO00417.1 - 0.0018 17.8 0.0 0.0049 16.3 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 EDO00417.1 - 0.0082 16.2 0.1 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_psq PF05225.11 EDO00417.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DAO PF01266.19 EDO00418.1 - 3.6e-33 114.9 0.0 7e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO00418.1 - 0.011 15.7 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO00418.1 - 0.032 13.1 0.0 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EDO00418.1 - 0.075 12.9 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDO00418.1 - 0.082 11.5 0.4 5.4 5.5 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EDO00418.1 - 0.087 12.5 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EDO00418.1 - 0.17 10.6 0.0 0.39 9.5 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A CBM_1 PF00734.13 EDO00419.1 - 7.6e-12 44.6 14.1 2.3e-11 43.1 9.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 EDO00419.1 - 1e-07 32.0 0.1 1.4e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MTHFR_C PF12225.3 EDO00419.1 - 0.00087 18.7 1.4 0.011 15.2 0.3 2.2 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal AMP-binding PF00501.23 EDO00421.1 - 4.6e-38 130.6 0.0 2.5e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Methyltransf_2 PF00891.13 EDO00422.1 - 1.3e-28 99.8 0.0 1.9e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EDO00422.1 - 0.00047 19.7 0.0 0.0057 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 EDO00422.1 - 0.0056 16.0 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EDO00422.1 - 0.0063 17.0 0.0 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain HTH_Tnp_ISL3 PF13542.1 EDO00422.1 - 0.011 14.9 0.1 0.043 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Methyltransf_23 PF13489.1 EDO00422.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GMC_oxred_N PF00732.14 EDO00423.1 - 3.9e-54 183.7 0.0 5.1e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO00423.1 - 3.9e-29 101.7 0.0 6.2e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDO00423.1 - 2.1e-06 26.8 0.1 1.2e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO00423.1 - 2.1e-05 23.5 0.1 0.046 12.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDO00423.1 - 2.8e-05 24.0 0.1 9.2e-05 22.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDO00423.1 - 0.0011 17.5 0.1 0.006 15.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EDO00423.1 - 0.0018 18.1 0.3 0.0033 17.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO00423.1 - 0.0023 17.0 0.2 0.0047 16.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EDO00423.1 - 0.0035 17.7 0.6 0.0092 16.3 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDO00423.1 - 0.0065 15.4 0.2 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EDO00423.1 - 0.043 13.8 0.5 0.43 10.6 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO00423.1 - 0.051 12.6 0.2 0.099 11.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EDO00423.1 - 0.052 13.3 0.6 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EDO00423.1 - 0.11 11.1 0.2 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GSH_synth_ATP PF03917.12 EDO00425.1 - 0.036 12.6 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain DAHP_synth_1 PF00793.15 EDO00425.1 - 0.1 11.3 0.0 0.32 9.6 0.0 1.7 2 0 0 2 2 2 0 DAHP synthetase I family HLH PF00010.21 EDO00428.1 - 1.5e-07 31.0 0.0 3.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1741 PF08427.5 EDO00431.1 - 8.2e-84 280.7 0.3 1.5e-83 279.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 EDO00432.1 - 1.1e-17 63.9 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Dabb PF07876.7 EDO00433.1 - 1.6e-12 47.6 1.9 2e-08 34.5 0.1 2.1 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain RTA1 PF04479.8 EDO00434.1 - 5e-45 153.7 14.5 5e-45 153.7 10.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3754 PF12576.3 EDO00434.1 - 1.7 8.2 5.0 0.43 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) HMGL-like PF00682.14 EDO00436.1 - 1.6e-71 240.7 0.6 2.7e-71 239.9 0.4 1.4 1 0 0 1 1 1 1 HMGL-like CFEM PF05730.6 EDO00437.1 - 2.5e-10 40.0 14.6 4.5e-10 39.2 10.1 1.4 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 EDO00437.1 - 5.8 5.4 14.7 7.2 5.1 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_N PF08240.7 EDO00439.1 - 1.2e-10 41.1 0.0 3.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO00439.1 - 5.1e-10 39.0 0.0 9.6e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3595 PF12166.3 EDO00443.1 - 0.21 10.3 0.4 0.27 9.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Sugar_tr PF00083.19 EDO00446.1 - 5.5e-72 242.7 19.1 4.3e-54 183.7 6.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO00446.1 - 1.6e-10 40.2 33.5 1.4e-05 23.9 5.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily CM_2 PF01817.16 EDO00450.1 - 2.5e-13 49.8 0.0 3.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Dioxygenase_C PF00775.16 EDO00451.1 - 2.2e-11 43.3 0.2 3.6e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Amidohydro_4 PF13147.1 EDO00452.1 - 3.1e-09 37.2 1.1 9.1e-09 35.7 0.7 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EDO00452.1 - 0.00021 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDO00452.1 - 0.00064 19.0 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EDO00452.1 - 0.0016 18.1 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family C2 PF00168.25 EDO00453.1 - 7.9e-22 76.9 0.0 7.7e-16 57.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain RNase_H PF00075.19 EDO00456.1 - 0.13 12.5 0.0 3.3 8.0 0.0 2.3 1 1 1 2 2 2 0 RNase H Zn_clus PF00172.13 EDO00457.1 - 0.00013 21.7 5.1 0.00013 21.7 3.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO00457.1 - 0.076 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Bromodomain PF00439.20 EDO00458.1 - 2.1e-35 120.4 1.0 8.5e-22 76.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EDO00459.1 - 4.3e-23 81.3 0.4 6.1e-23 80.8 0.3 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Init_tRNA_PT PF04179.7 EDO00459.1 - 0.06 12.2 1.2 0.093 11.5 0.8 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase MGS PF02142.17 EDO00459.1 - 0.069 13.0 0.3 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 MGS-like domain Nop14 PF04147.7 EDO00459.1 - 5 4.9 37.8 1.8 6.3 3.6 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 EDO00459.1 - 10 5.0 31.2 0.66 8.9 11.1 2.1 2 0 0 2 2 2 0 BUD22 DDE_1 PF03184.14 EDO00461.1 - 1e-11 44.4 0.2 2.7e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO00461.1 - 0.016 15.0 7.3 0.029 14.2 5.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Glycophorin_A PF01102.13 EDO00462.1 - 7.7e-06 25.6 1.9 1.5e-05 24.7 1.3 1.5 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.1 EDO00462.1 - 0.0012 18.5 0.7 0.0027 17.4 0.5 1.7 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 EDO00462.1 - 0.016 15.6 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EDO00462.1 - 0.021 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF4328 PF14219.1 EDO00462.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Plasmodium_Vir PF05795.6 EDO00462.1 - 0.053 12.7 0.2 0.071 12.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NicO PF03824.11 EDO00462.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Adeno_E3_CR2 PF02439.10 EDO00462.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2561 PF10812.3 EDO00462.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CcmD PF04995.9 EDO00462.1 - 0.21 11.3 0.6 0.37 10.5 0.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) P12 PF12669.2 EDO00462.1 - 8.4 6.6 6.5 1.6 8.9 0.1 2.8 3 0 0 3 3 3 0 Virus attachment protein p12 family DUF536 PF04394.9 EDO00463.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF536 DUF1218 PF06749.7 EDO00465.1 - 0.1 13.0 0.9 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) UPF0154 PF03672.8 EDO00465.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EII-Sor PF03609.9 EDO00465.1 - 0.18 11.0 5.8 0.56 9.4 0.2 2.1 1 1 1 2 2 2 0 PTS system sorbose-specific iic component Sec6 PF06046.8 EDO00467.1 - 3.8e-170 566.7 4.6 5.8e-170 566.0 3.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF713 PF05218.9 EDO00467.1 - 0.0077 15.9 0.8 0.0077 15.9 0.6 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF713) DUF755 PF05501.6 EDO00467.1 - 0.25 11.3 0.1 0.51 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DASH_Dam1 PF08653.5 EDO00467.1 - 1.2 8.9 6.3 2 8.2 0.2 4.0 4 1 0 4 4 4 0 DASH complex subunit Dam1 Ribosomal_L30 PF00327.15 EDO00468.1 - 7.5e-14 51.0 0.1 1.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF382 PF04037.8 EDO00468.1 - 0.082 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF382) MRG PF05712.8 EDO00469.1 - 2.2e-45 153.9 0.0 6.2e-43 145.9 0.0 2.4 1 1 0 1 1 1 1 MRG Neur_chan_memb PF02932.11 EDO00470.1 - 1.7 8.4 4.4 2.7 7.8 3.1 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3824 PF12868.2 EDO00470.1 - 2.2 9.2 7.2 0.24 12.3 1.6 1.9 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Tudor-knot PF11717.3 EDO00471.1 - 0.03 14.0 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.5 EDO00472.1 - 2.5e-28 97.5 1.0 4.5e-28 96.7 0.7 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Perilipin PF03036.11 EDO00472.1 - 0.022 13.5 0.6 0.026 13.3 0.4 1.1 1 0 0 1 1 1 0 Perilipin family Prefoldin_2 PF01920.15 EDO00472.1 - 0.054 13.2 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EDO00472.1 - 0.057 13.2 0.3 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NTR2 PF15458.1 EDO00472.1 - 0.058 12.6 1.1 0.077 12.2 0.8 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF1843 PF08898.5 EDO00472.1 - 0.061 13.3 0.7 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Vps53_N PF04100.7 EDO00472.1 - 0.23 10.2 1.3 0.64 8.7 0.9 1.7 1 1 0 1 1 1 0 Vps53-like, N-terminal IncA PF04156.9 EDO00472.1 - 0.54 9.8 3.9 2.2 7.8 2.6 2.0 1 1 0 1 1 1 0 IncA protein NUC173 PF08161.7 EDO00474.1 - 4.5e-81 270.9 0.9 5e-77 257.7 0.0 3.8 3 0 0 3 3 3 2 NUC173 domain Vac14_Fab1_bd PF12755.2 EDO00474.1 - 0.011 16.1 0.0 15 6.0 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CENP-Q PF13094.1 EDO00475.1 - 3.9e-37 127.7 1.4 3.9e-37 127.7 0.9 3.4 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit SPO22 PF08631.5 EDO00477.1 - 2.3e-79 266.3 7.4 5.9e-79 265.0 5.1 1.7 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EDO00477.1 - 1.3e-06 28.2 0.1 6.4e-06 26.0 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR_3 PF13812.1 EDO00477.1 - 0.038 14.2 0.1 15 6.1 0.0 4.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain YadA_stalk PF05662.9 EDO00478.1 - 0.26 11.1 2.0 0.41 10.4 1.4 1.3 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin Omega-toxin PF06357.6 EDO00479.1 - 0.021 14.4 2.9 0.021 14.4 2.0 2.5 3 0 0 3 3 3 0 Omega-atracotoxin Ald_Xan_dh_C2 PF02738.13 EDO00480.1 - 4.8e-105 351.9 0.1 7.1e-105 351.3 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EDO00480.1 - 9.8e-50 168.3 0.0 1.6e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EDO00480.1 - 1.2e-31 108.7 0.1 2.8e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EDO00480.1 - 3.2e-30 104.4 0.1 6.7e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EDO00480.1 - 2.1e-12 46.7 0.1 4.9e-06 26.3 0.0 2.5 1 1 1 2 2 2 2 [2Fe-2S] binding domain Fer2 PF00111.22 EDO00480.1 - 4.8e-08 32.6 0.1 1.2e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EDO00480.1 - 0.082 12.8 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 DUF2505 PF10698.4 EDO00480.1 - 0.12 11.8 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) CtaG_Cox11 PF04442.9 EDO00483.1 - 1.1e-58 197.3 0.0 1.4e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cupin_2 PF07883.6 EDO00484.1 - 2.1e-16 59.1 0.1 4.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EDO00484.1 - 2.2e-06 27.1 0.1 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EDO00484.1 - 6.7e-06 25.8 0.0 9.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 EDO00484.1 - 0.00014 21.8 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family GPI PF06560.6 EDO00484.1 - 0.0038 16.2 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) CENP-C_C PF11699.3 EDO00484.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_3 PF05899.7 EDO00484.1 - 0.038 13.3 0.1 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EDO00484.1 - 0.04 13.5 0.1 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Cupin MarB PF13999.1 EDO00484.1 - 0.07 12.7 0.0 0.4 10.2 0.0 2.0 1 1 1 2 2 2 0 MarB protein EutQ PF06249.7 EDO00484.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ JmjC PF02373.17 EDO00484.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase MannoseP_isomer PF01050.13 EDO00484.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase IMS PF00817.15 EDO00485.1 - 3.7e-28 98.1 0.0 1.2e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EDO00485.1 - 2.1e-05 24.4 0.1 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EDO00485.1 - 0.04 13.9 0.2 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif DUF3545 PF12065.3 EDO00487.1 - 2.1 8.1 6.7 5.1 6.9 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Amino_oxidase PF01593.19 EDO00489.1 - 6.7e-13 48.5 0.1 1.8e-10 40.5 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDO00489.1 - 6.7e-12 45.2 0.3 1.6e-11 44.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDO00489.1 - 1.3e-05 25.3 0.2 0.003 17.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO00489.1 - 7.6e-05 22.5 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EDO00489.1 - 0.00039 19.4 1.6 0.0017 17.2 0.2 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO00489.1 - 0.0009 17.8 0.1 0.5 8.7 0.1 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EDO00489.1 - 0.002 18.0 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDO00489.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain V-SNARE PF05008.10 EDO00490.1 - 1.2e-22 79.8 3.7 1.2e-22 79.8 2.6 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EDO00490.1 - 7.4e-19 67.5 3.9 7.4e-19 67.5 2.7 3.0 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EDO00490.1 - 0.00077 19.1 4.5 0.0018 17.9 0.3 2.6 2 2 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EDO00490.1 - 0.0097 14.0 3.8 0.18 9.8 0.4 2.3 2 1 0 2 2 2 2 Fusion glycoprotein F0 Synaptobrevin PF00957.16 EDO00490.1 - 0.015 14.8 3.1 0.044 13.3 1.5 2.2 1 1 1 2 2 2 0 Synaptobrevin DUF1542 PF07564.6 EDO00490.1 - 0.025 14.6 0.5 0.086 12.8 0.4 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Pex24p PF06398.6 EDO00490.1 - 0.13 11.0 0.4 0.26 10.0 0.2 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin LMBR1 PF04791.11 EDO00490.1 - 0.13 10.8 1.2 0.19 10.2 0.8 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.6 EDO00490.1 - 0.25 9.9 8.4 0.66 8.5 1.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_E56 PF04639.7 EDO00490.1 - 0.39 9.3 3.6 0.14 10.7 0.2 1.8 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Use1 PF09753.4 EDO00490.1 - 0.71 9.2 9.7 0.22 10.9 0.1 2.2 1 1 1 2 2 2 0 Membrane fusion protein Use1 Histone_HNS PF00816.16 EDO00490.1 - 2.4 8.7 4.9 0.93 10.0 0.7 2.0 2 0 0 2 2 2 0 H-NS histone family Seryl_tRNA_N PF02403.17 EDO00490.1 - 6.2 6.8 9.1 3.9 7.5 0.0 3.2 3 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EDO00490.1 - 6.3 5.6 11.2 1.3 7.8 0.9 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_23 PF13489.1 EDO00492.1 - 9.6e-07 28.6 0.1 9.7e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain DUF444 PF04285.7 EDO00492.1 - 1 7.9 3.4 1.5 7.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) BetaGal_dom4_5 PF13364.1 EDO00493.1 - 0.039 14.2 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF2407_C PF13373.1 EDO00494.1 - 1.1e-35 122.6 0.1 1.4e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EDO00494.1 - 6.2e-25 87.2 0.0 1.1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EDO00494.1 - 0.037 13.4 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family Aminotran_1_2 PF00155.16 EDO00495.1 - 6e-57 193.2 0.0 2.6e-54 184.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO00495.1 - 0.0003 20.0 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EDO00495.1 - 0.0022 16.3 0.0 0.004 15.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDO00495.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EDO00495.1 - 0.21 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V adh_short PF00106.20 EDO00496.1 - 9.8e-14 51.6 0.1 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO00496.1 - 1.4e-05 24.8 0.0 5.3e-05 22.9 0.0 1.6 1 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDO00496.1 - 6.8e-05 22.7 0.0 9.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rhodanese PF00581.15 EDO00497.1 - 0.0023 18.2 0.0 0.013 15.8 0.0 2.1 1 1 0 1 1 1 1 Rhodanese-like domain HTH_psq PF05225.11 EDO00498.1 - 1.5e-08 34.0 0.0 2.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDO00498.1 - 2e-06 27.1 0.1 6.3e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease NUMOD1 PF07453.8 EDO00498.1 - 0.13 12.1 0.2 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 NUMOD1 domain DDE_1 PF03184.14 EDO00499.1 - 7.5e-12 44.8 0.0 1.8e-11 43.6 0.0 1.5 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO00499.1 - 3.3e-05 23.3 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDO00500.1 - 9.8e-36 122.9 0.6 9.8e-36 122.9 0.4 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO00500.1 - 1.1e-13 50.7 0.0 3.6e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3450 PF11932.3 EDO00500.1 - 1.7 7.8 7.8 0.076 12.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HSP70 PF00012.15 EDO00501.1 - 0.019 12.8 0.7 0.061 11.2 0.0 2.2 3 0 0 3 3 3 0 Hsp70 protein HyaE PF07449.6 EDO00502.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Band_3_cyto PF07565.8 EDO00502.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Collagen PF01391.13 EDO00504.1 - 0.0038 16.7 2.4 0.0053 16.2 1.6 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-RING-like PF08746.6 EDO00504.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RING-like domain RVT_1 PF00078.22 EDO00505.1 - 1.4e-31 109.5 0.3 2.8e-31 108.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDO00505.1 - 0.0093 15.5 0.5 0.055 13.0 0.1 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos_2 PF14529.1 EDO00506.1 - 1.1e-06 28.2 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDO00506.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DDE_1 PF03184.14 EDO00508.1 - 1.8e-09 37.0 0.0 3.8e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO00508.1 - 2.8e-07 30.2 0.0 6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AA_permease PF00324.16 EDO00511.1 - 2.9e-98 329.2 31.9 3.8e-98 328.9 22.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO00511.1 - 5.9e-18 64.6 34.2 9.4e-18 63.9 23.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 EDO00511.1 - 0.0065 15.8 0.1 0.0065 15.8 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF3487) Orthoreo_P10 PF07204.6 EDO00511.1 - 0.42 10.3 3.9 0.41 10.4 1.3 2.0 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF1772 PF08592.6 EDO00511.1 - 2.3 7.9 12.9 0.13 11.9 1.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.13 EDO00513.1 - 5.9e-09 35.1 0.4 1.5e-08 33.8 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO00513.1 - 4.3e-08 32.9 7.6 7.7e-08 32.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku_PK_bind PF08785.6 EDO00513.1 - 0.0042 16.9 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like HGTP_anticodon PF03129.15 EDO00514.1 - 0.0039 17.1 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain DUF2387 PF09526.5 EDO00514.1 - 0.1 12.5 0.8 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) CBF PF03914.12 EDO00515.1 - 1.6e-46 157.7 1.5 3.6e-46 156.5 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family 4HBT PF03061.17 EDO00517.1 - 2e-08 34.2 0.1 4.1e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.15 EDO00518.1 - 1e-70 236.4 0.0 1.2e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EDO00518.1 - 1.7e-06 28.8 0.2 2.8e-06 28.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO00518.1 - 1.8e-06 27.8 0.0 3.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO00518.1 - 1.4e-05 25.3 0.1 3.2e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDO00518.1 - 0.0006 19.1 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EDO00518.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO00518.1 - 0.03 14.3 0.1 0.049 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 EDO00518.1 - 0.051 12.6 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.22 EDO00518.1 - 0.067 13.4 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EDO00518.1 - 0.088 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 EDO00518.1 - 0.098 12.9 0.6 0.17 12.2 0.4 1.5 1 1 0 1 1 1 0 AAA domain V-ATPase_C PF03223.10 EDO00519.1 - 5.4e-113 377.6 1.9 6.4e-113 377.4 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EDO00519.1 - 0.065 13.5 0.9 0.61 10.4 0.0 2.5 2 1 0 2 2 2 0 mRNA capping enzyme, C-terminal domain GvpL_GvpF PF06386.6 EDO00521.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF2236 PF09995.4 EDO00522.1 - 0.00017 20.9 0.0 0.00051 19.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GMC_oxred_N PF00732.14 EDO00526.1 - 1.2e-58 198.6 0.0 1.6e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO00526.1 - 9.1e-38 129.7 0.0 3.2e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EDO00526.1 - 7.6e-08 31.6 0.0 0.011 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDO00526.1 - 1e-05 24.6 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EDO00526.1 - 7.8e-05 22.8 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO00526.1 - 9e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO00526.1 - 0.0014 18.5 0.0 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO00526.1 - 0.0033 17.2 0.1 0.0064 16.2 0.1 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EDO00526.1 - 0.0053 15.2 0.0 0.031 12.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EDO00526.1 - 0.0054 15.6 0.1 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EDO00526.1 - 0.012 14.5 0.0 0.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EDO00526.1 - 0.023 13.5 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EDO00526.1 - 0.035 13.1 0.1 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EDO00526.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Mod_r PF07200.8 EDO00528.1 - 3.2e-11 43.3 2.9 5.3e-11 42.6 2.0 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.28 EDO00531.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDO00531.1 - 0.0065 16.1 0.3 0.024 14.3 0.0 2.2 3 0 0 3 3 3 1 F-box-like PAG PF15347.1 EDO00531.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Rad10 PF03834.9 EDO00533.1 - 1.6e-30 104.5 0.1 2.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EDO00533.1 - 0.00014 21.9 0.0 0.00042 20.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EDO00533.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4604 PF15377.1 EDO00533.1 - 5.6 7.1 7.7 0.5 10.5 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) AA_permease_2 PF13520.1 EDO00534.1 - 8.5e-48 162.9 43.3 8.5e-48 162.9 30.0 1.9 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDO00534.1 - 1.2e-19 69.9 43.7 3.2e-19 68.6 30.5 1.4 1 1 0 1 1 1 1 Amino acid permease YlaC PF10777.4 EDO00534.1 - 0.038 13.5 0.0 0.038 13.5 0.0 2.8 3 1 1 4 4 4 0 Inner membrane protein YlaC Methyltransf_23 PF13489.1 EDO00535.1 - 8.6e-17 61.3 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO00535.1 - 0.0035 17.6 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO00535.1 - 0.022 15.2 0.0 0.12 12.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDO00535.1 - 0.058 13.8 0.0 0.5 10.8 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF2252 PF10009.4 EDO00536.1 - 1.1 8.0 8.4 2.5 6.9 5.8 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) AAA_23 PF13476.1 EDO00537.1 - 0.0088 16.3 5.7 0.015 15.5 3.9 1.3 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EDO00537.1 - 0.0094 15.5 10.5 0.02 14.4 7.3 1.5 1 0 0 1 1 1 1 IncA protein Phage_GP20 PF06810.6 EDO00537.1 - 0.015 14.7 9.4 0.037 13.4 6.5 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 LEA_3 PF03242.8 EDO00537.1 - 0.017 15.3 0.0 0.065 13.4 0.0 2.0 1 0 0 1 1 1 0 Late embryogenesis abundant protein NPV_P10 PF05531.7 EDO00537.1 - 0.034 14.3 2.1 9.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UBN2_3 PF14244.1 EDO00537.1 - 0.04 13.4 1.3 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TMF_TATA_bd PF12325.3 EDO00537.1 - 0.2 11.4 17.2 0.59 9.8 11.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EDO00537.1 - 0.23 11.6 15.1 0.69 10.0 1.8 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4294 PF14127.1 EDO00537.1 - 0.42 10.2 5.6 0.91 9.1 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Syntaxin PF00804.20 EDO00537.1 - 0.61 10.2 11.2 4.4 7.5 5.1 2.7 1 1 1 2 2 2 0 Syntaxin DUF848 PF05852.6 EDO00537.1 - 0.62 9.9 11.1 1.6 8.5 7.7 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 EDO00537.1 - 0.7 8.8 14.4 1.4 7.9 10.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EDO00537.1 - 1.2 8.2 18.2 3.9 6.6 12.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EDO00537.1 - 1.4 6.6 8.2 2 6.1 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EDO00537.1 - 1.5 8.8 13.2 5.8 6.9 9.2 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 EDO00537.1 - 2.3 8.3 8.6 2.5 8.2 1.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EDO00537.1 - 3.5 7.3 9.4 1.2 8.8 3.3 2.2 2 0 0 2 2 2 0 Laminin Domain II BMFP PF04380.8 EDO00537.1 - 8.3 6.6 16.1 2.5e+03 -1.4 10.0 3.4 1 1 0 1 1 1 0 Membrane fusogenic activity DUF4446 PF14584.1 EDO00537.1 - 8.4 6.2 11.4 0.66 9.7 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) eIF3_p135 PF12807.2 EDO00538.1 - 0.14 12.0 1.3 0.27 11.1 0.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TMF_TATA_bd PF12325.3 EDO00539.1 - 4.2e-38 129.7 12.1 4.2e-38 129.7 8.4 6.8 3 2 2 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EDO00539.1 - 1.6e-18 66.2 17.9 1.6e-18 66.2 12.4 9.2 5 4 3 8 8 8 1 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.1 EDO00539.1 - 0.01 15.4 9.8 1.7 8.3 0.2 3.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif NdhN PF11909.3 EDO00539.1 - 0.013 14.8 0.1 0.037 13.3 0.1 1.7 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Ceramidase PF05875.7 EDO00540.1 - 3.2e-84 282.1 9.9 9.8e-84 280.5 6.9 1.7 1 1 0 1 1 1 1 Ceramidase DUF4401 PF14351.1 EDO00540.1 - 0.0027 16.7 4.5 0.0046 15.9 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF788 PF05620.6 EDO00540.1 - 0.029 14.2 0.2 0.062 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Renin_r PF07850.9 EDO00540.1 - 0.048 14.0 0.1 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 Renin receptor-like protein Oxidored_q2 PF00420.19 EDO00540.1 - 2.8 7.5 7.1 0.68 9.5 2.5 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Prefoldin_2 PF01920.15 EDO00541.1 - 3e-13 49.4 4.6 4.6e-13 48.8 3.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit YgaB PF14182.1 EDO00541.1 - 0.021 15.0 5.2 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 YgaB-like protein Prefoldin PF02996.12 EDO00541.1 - 0.048 13.3 0.4 0.048 13.3 0.3 2.3 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 EDO00541.1 - 0.051 13.3 3.4 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.1 EDO00541.1 - 0.057 13.4 1.9 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Tropomyosin_1 PF12718.2 EDO00541.1 - 0.06 13.1 5.9 0.11 12.3 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Laminin_I PF06008.9 EDO00541.1 - 0.071 12.4 3.7 0.54 9.5 0.1 2.0 2 0 0 2 2 2 0 Laminin Domain I IncA PF04156.9 EDO00541.1 - 0.11 12.0 8.3 0.48 10.0 5.8 1.8 1 1 0 1 1 1 0 IncA protein DUF2730 PF10805.3 EDO00541.1 - 0.16 11.7 2.5 1.3 8.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF2968 PF11180.3 EDO00541.1 - 0.16 11.3 3.6 1.3 8.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Seryl_tRNA_N PF02403.17 EDO00541.1 - 0.2 11.6 5.4 0.3 11.1 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Microtub_assoc PF07989.6 EDO00541.1 - 0.23 11.2 3.3 1 9.2 0.1 2.3 2 0 0 2 2 2 0 Microtubule associated Snf7 PF03357.16 EDO00541.1 - 0.25 10.6 4.7 2 7.7 0.1 2.1 2 0 0 2 2 2 0 Snf7 AIP3 PF03915.8 EDO00541.1 - 0.27 10.0 4.1 0.31 9.9 2.8 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF869 PF05911.6 EDO00541.1 - 0.37 8.9 5.4 0.73 8.0 3.7 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4407 PF14362.1 EDO00541.1 - 0.42 9.5 2.9 1 8.2 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EDO00541.1 - 0.44 10.3 7.0 3 7.5 0.2 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 EDO00541.1 - 0.45 10.6 8.4 2.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 EDO00541.1 - 0.47 10.3 6.4 3.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FlxA PF14282.1 EDO00541.1 - 0.48 10.3 15.1 1.2 9.1 0.4 2.3 1 1 1 2 2 2 0 FlxA-like protein Trigger_N PF05697.8 EDO00541.1 - 0.49 10.1 4.0 1.6 8.5 1.0 2.2 1 1 0 2 2 2 0 Bacterial trigger factor protein (TF) DUF812 PF05667.6 EDO00541.1 - 0.79 8.1 7.9 1.2 7.5 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF641 PF04859.7 EDO00541.1 - 0.9 9.2 4.7 2.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 EDO00541.1 - 0.91 9.4 8.7 2.2 8.2 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 EDO00541.1 - 1.1 9.4 5.4 0.94 9.6 0.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 EDO00541.1 - 1.6 7.2 6.9 2.3 6.6 0.2 2.0 2 0 0 2 2 2 0 Tektin family Phage_GP20 PF06810.6 EDO00541.1 - 1.6 8.1 8.8 2.1 7.7 1.3 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 EDO00541.1 - 1.8 8.5 5.1 1.4 8.9 0.1 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EDO00541.1 - 1.8 8.4 12.4 0.4 10.5 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EDO00541.1 - 2.3 8.1 8.2 2.2 8.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 EDO00541.1 - 2.8 7.2 8.6 3.2 7.0 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) APG6 PF04111.7 EDO00541.1 - 2.9 6.8 7.9 5.1 6.0 1.1 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.2 EDO00541.1 - 3.3 7.8 6.1 19 5.3 0.2 2.3 2 0 0 2 2 2 0 Central kinetochore-associated LXG PF04740.7 EDO00541.1 - 3.3 7.4 7.6 0.83 9.4 0.3 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily Syntaxin PF00804.20 EDO00541.1 - 4.1 7.6 10.5 1.2e+02 2.9 7.1 2.0 1 1 0 1 1 1 0 Syntaxin PspA_IM30 PF04012.7 EDO00541.1 - 4.5 6.5 8.9 9.9 5.4 0.3 2.0 2 0 0 2 2 2 0 PspA/IM30 family CENP-Q PF13094.1 EDO00541.1 - 4.5 7.2 9.7 3.6 7.6 0.6 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 EDO00541.1 - 5 6.8 7.4 1.9 8.2 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1319 PF07028.6 EDO00541.1 - 9.6 6.4 9.7 5.7 7.1 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) Mito_carr PF00153.22 EDO00544.1 - 1.6e-56 188.0 2.6 2.2e-19 68.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_Fe-S_N PF10399.4 EDO00544.1 - 0.13 11.4 1.1 0.31 10.2 0.7 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CN_hydrolase PF00795.17 EDO00545.1 - 1.2e-19 70.4 0.0 3e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase PEMT PF04191.8 EDO00546.1 - 2.5e-18 66.1 0.4 2.7e-18 65.9 0.3 1.0 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.6 EDO00548.1 - 2.3e-48 163.7 1.7 1.3e-47 161.3 0.0 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal Gryzun PF07919.7 EDO00549.1 - 5.3e-119 398.0 0.0 7.1e-119 397.6 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EDO00549.1 - 1.7e-94 315.9 0.1 1.4e-87 293.2 0.2 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EDO00549.1 - 0.00077 19.2 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 EDO00551.1 - 1.6e-22 80.5 0.0 2.5e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO00551.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO00551.1 - 0.0014 18.4 0.0 0.0046 16.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EDO00551.1 - 0.0016 16.9 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 EDO00551.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PTCB-BRCT PF12738.2 EDO00552.1 - 1.8e-26 91.7 0.8 3.2e-17 62.1 0.0 4.4 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 EDO00552.1 - 5.6e-18 64.8 0.4 1.3e-07 31.6 0.0 5.7 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain DUF4078 PF13300.1 EDO00553.1 - 3.1e-29 100.9 18.6 3.1e-29 100.9 12.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) DUF903 PF06004.7 EDO00553.1 - 0.02 14.4 0.5 0.083 12.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Homoserine_dh PF00742.14 EDO00554.1 - 6.6e-52 175.7 0.0 8.8e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EDO00554.1 - 2.7e-17 63.2 0.0 4.4e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.16 EDO00554.1 - 0.018 14.1 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase AsnA PF03590.10 EDO00554.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 2 0 0 2 2 2 0 Aspartate-ammonia ligase Methyltransf_4 PF02390.12 EDO00555.1 - 4.7e-48 162.8 0.0 5.9e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDO00555.1 - 0.011 15.0 0.1 0.019 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EDO00555.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO00555.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EDO00555.1 - 0.15 11.6 0.1 0.25 10.9 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDO00555.1 - 0.15 12.5 0.0 1.4 9.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain PXA PF02194.10 EDO00556.1 - 2e-51 174.2 0.1 4.8e-51 172.9 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EDO00556.1 - 7.9e-29 100.0 0.5 2e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EDO00556.1 - 4.6e-21 74.7 0.1 1.2e-20 73.4 0.1 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EDO00556.1 - 1.3e-12 47.8 0.0 3.7e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain FANCI_S1-cap PF14674.1 EDO00556.1 - 0.1 12.6 0.1 0.37 10.8 0.1 2.0 1 0 0 1 1 1 0 FANCI solenoid 1 cap Serum_albumin PF00273.15 EDO00560.1 - 0.096 12.1 0.4 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Serum albumin family HMG_CoA_synt_C PF08540.5 EDO00563.1 - 1.5e-105 352.7 1.8 1.9e-105 352.3 1.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EDO00563.1 - 1.8e-94 314.1 0.2 2.8e-94 313.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Abhydrolase_3 PF07859.8 EDO00564.1 - 2.9e-35 121.7 0.0 5.1e-34 117.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDO00564.1 - 0.00022 20.0 0.0 0.00041 19.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDO00564.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pex14_N PF04695.8 EDO00565.1 - 3.5e-35 121.0 0.0 3.5e-35 121.0 0.0 2.9 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1043 PF06295.7 EDO00565.1 - 0.027 14.0 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) IncA PF04156.9 EDO00565.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.5 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 EDO00565.1 - 0.28 11.0 1.7 1.3 8.8 0.6 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GRIM-19 PF06212.7 EDO00565.1 - 1.5 8.5 4.6 0.35 10.5 0.3 1.9 2 0 0 2 2 2 0 GRIM-19 protein SlyX PF04102.7 EDO00565.1 - 7.7 6.9 6.7 2.8 8.3 0.4 2.8 2 2 0 2 2 2 0 SlyX Ndc80_HEC PF03801.8 EDO00566.1 - 8.6e-62 207.2 0.0 2.1e-61 206.0 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.16 EDO00566.1 - 0.0039 16.7 45.2 0.026 13.9 14.5 2.4 2 0 0 2 2 2 2 Intermediate filament protein FliJ PF02050.11 EDO00566.1 - 0.0084 16.1 7.2 0.0084 16.1 5.0 3.7 3 1 0 3 3 3 2 Flagellar FliJ protein NPV_P10 PF05531.7 EDO00566.1 - 0.085 13.1 8.4 5.7 7.2 0.2 3.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WASH_WAHD PF11945.3 EDO00566.1 - 0.15 11.2 10.1 0.012 14.9 3.4 1.7 2 0 0 2 2 2 0 WAHD domain of WASH complex OmpH PF03938.9 EDO00566.1 - 0.63 9.9 40.7 0.42 10.5 8.0 3.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 EDO00566.1 - 0.75 7.0 36.1 0.31 8.3 11.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 EDO00566.1 - 5 4.8 32.4 2.6 5.7 9.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EDO00566.1 - 7.6 6.3 61.8 0.3 10.9 8.3 4.2 2 2 2 4 4 4 0 Tropomyosin like RRM_1 PF00076.17 EDO00567.1 - 1.9e-20 72.2 0.1 2.1e-11 43.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00567.1 - 1.6e-15 56.8 0.0 2.1e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00567.1 - 1.7e-12 46.9 0.0 4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.2 EDO00569.1 - 1.5e-38 132.3 0.0 2.2e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO00569.1 - 7.5e-10 38.7 0.0 1.4e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDO00569.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily GST_C PF00043.20 EDO00570.1 - 3.5e-10 39.7 0.0 8.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDO00570.1 - 1.3e-06 28.5 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDO00570.1 - 1.4e-06 28.4 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO00570.1 - 1.6e-06 28.0 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO00570.1 - 0.00056 19.7 0.1 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO00570.1 - 0.0026 18.1 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 EDO00571.1 - 5.9e-97 325.5 0.1 6.8e-97 325.3 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDO00571.1 - 1.4e-06 28.0 0.3 8.5e-06 25.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FtsJ PF01728.14 EDO00572.1 - 3.5e-09 36.9 0.0 6.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase La PF05383.12 EDO00573.1 - 5.1e-17 61.4 0.4 1.4e-16 60.0 0.3 1.8 1 0 0 1 1 1 1 La domain Got1 PF04178.7 EDO00574.1 - 6.1e-30 103.7 16.2 8.7e-30 103.2 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family YrzO PF14142.1 EDO00575.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 YrzO-like protein HLH PF00010.21 EDO00576.1 - 1.8e-12 46.7 0.0 7.7e-12 44.7 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S21 PF01165.15 EDO00577.1 - 2.9e-11 42.6 0.8 4.7e-11 41.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 EDO00578.1 - 3.9e-11 42.9 0.3 1.4e-10 41.1 0.3 2.0 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EDO00578.1 - 0.041 13.5 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_28 PF00295.12 EDO00579.1 - 1.7e-32 112.6 3.7 1.8e-29 102.7 2.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EDO00579.1 - 0.0018 18.0 14.8 0.0044 16.7 7.2 2.8 1 1 1 2 2 2 2 Right handed beta helix region Pentapeptide_4 PF13599.1 EDO00579.1 - 0.0063 16.3 0.3 0.092 12.5 0.0 2.6 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) zf-H2C2 PF09337.5 EDO00579.1 - 0.1 12.0 0.1 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger p450 PF00067.17 EDO00580.1 - 1.9e-41 142.1 0.0 2.3e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDO00581.1 - 5.6e-10 38.3 0.0 7.1e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EDO00582.1 - 2.2e-19 69.2 0.0 8.6e-17 60.6 0.0 2.2 2 0 0 2 2 2 2 Transferase family Condensation PF00668.15 EDO00582.1 - 0.034 13.0 0.0 0.076 11.8 0.0 1.5 1 1 0 1 1 1 0 Condensation domain Foie-gras_1 PF11817.3 EDO00582.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 ZZ PF00569.12 EDO00584.1 - 2.4e-11 42.9 6.4 3.9e-11 42.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EDO00584.1 - 2.3e-08 33.9 0.0 4.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO00584.1 - 4.9e-06 26.5 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_2 PF13923.1 EDO00584.1 - 0.018 15.0 2.8 0.057 13.4 1.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EDO00585.1 - 3e-60 203.5 0.0 4.2e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00585.1 - 4.2e-29 101.4 0.0 6.2e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDO00585.1 - 3e-09 37.2 0.5 7.9e-09 35.9 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO00585.1 - 0.00067 18.6 0.0 0.00098 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PGI PF00342.14 EDO00586.1 - 4.1e-166 553.1 0.4 3.6e-96 322.5 0.0 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase HAUS6_N PF14661.1 EDO00588.1 - 1.4e-54 185.0 1.4 1.4e-54 185.0 1.0 2.2 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_72 PF03198.9 EDO00590.1 - 4e-127 423.5 7.4 4.9e-127 423.2 5.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EDO00590.1 - 5.6e-05 22.4 0.4 0.00036 19.8 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tyrosinase PF00264.15 EDO00591.1 - 6.9e-58 196.4 6.3 1.3e-57 195.5 4.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-B_box PF00643.19 EDO00593.1 - 0.034 14.0 1.7 0.034 14.0 1.2 1.7 2 0 0 2 2 2 0 B-box zinc finger Pterin_bind PF00809.17 EDO00594.1 - 4.2e-61 205.9 0.0 7.7e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EDO00594.1 - 4.2e-27 94.3 0.0 7.6e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pantoate_transf PF02548.10 EDO00594.1 - 0.027 13.6 0.1 0.05 12.7 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate hydroxymethyltransferase DDE_1 PF03184.14 EDO00595.1 - 2.2e-14 53.1 0.3 2.6e-13 49.6 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO00595.1 - 1.5e-09 37.2 0.1 2.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO00595.1 - 3.3e-08 33.2 0.3 1.2e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 EDO00595.1 - 0.0093 16.1 0.1 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix DUF3404 PF11884.3 EDO00595.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HTH_28 PF13518.1 EDO00595.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDO00595.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 NUMOD1 domain NMO PF03060.10 EDO00596.1 - 2.2e-71 240.6 1.9 2.7e-71 240.4 1.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDO00596.1 - 6.5e-10 38.4 0.6 1.2e-09 37.5 0.4 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDO00596.1 - 1.3e-07 30.8 2.9 2.4e-07 29.9 2.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EDO00596.1 - 0.00037 19.5 0.3 0.00055 18.9 0.2 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EDO00596.1 - 0.0014 17.6 0.6 0.0027 16.7 0.2 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Frag1 PF10277.4 EDO00598.1 - 2.6e-44 151.2 21.5 3e-44 151.0 14.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family RasGEF_N PF00618.15 EDO00599.1 - 0.1 12.6 0.1 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 RasGEF N-terminal motif Choline_transpo PF04515.7 EDO00602.1 - 6.1e-12 44.9 0.2 6.7e-12 44.7 0.2 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF4349 PF14257.1 EDO00603.1 - 0.04 13.1 6.3 0.057 12.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1129 PF06570.6 EDO00603.1 - 0.21 10.9 7.4 0.3 10.3 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Amnionless PF14828.1 EDO00603.1 - 0.32 9.4 1.8 0.51 8.7 1.2 1.3 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.11 EDO00603.1 - 0.46 8.6 5.5 0.65 8.1 3.8 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VirB3 PF05101.8 EDO00603.1 - 1.7 8.6 6.0 3.2 7.8 4.2 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF3844 PF12955.2 EDO00603.1 - 2 8.5 5.3 7.5 6.7 3.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) TIM21 PF08294.6 EDO00605.1 - 3e-43 146.9 0.0 3.9e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EDO00605.1 - 3.3e-05 23.3 0.0 7.5e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 EDO00606.1 - 2.4e-36 124.0 1.0 3.8e-36 123.4 0.2 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 EDO00606.1 - 0.086 12.4 0.0 0.086 12.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3275) NDT80_PhoG PF05224.7 EDO00615.1 - 2.3e-19 70.1 0.0 3.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF4611 PF15387.1 EDO00616.1 - 0.03 14.4 4.8 0.032 14.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EDO00616.1 - 0.03 13.8 3.9 0.027 13.9 2.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EDO00616.1 - 0.25 11.6 6.5 0.27 11.5 4.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EDO00616.1 - 0.28 10.7 3.0 0.25 10.9 2.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EDO00616.1 - 0.29 9.1 1.5 0.27 9.2 1.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 EDO00616.1 - 1.1 9.5 4.2 1.1 9.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CENP-B_dimeris PF09026.5 EDO00616.1 - 1.1 9.5 8.1 1.3 9.3 5.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 EDO00616.1 - 1.3 8.6 5.7 1.3 8.6 4.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Bd3614_N PF14442.1 EDO00616.1 - 5.4 6.9 7.3 5.9 6.8 5.1 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Pkinase PF00069.20 EDO00619.1 - 5.2e-37 127.3 0.0 8.3e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00619.1 - 2.5e-18 66.1 0.0 3.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Tnp_zf-ribbon_2 PF13842.1 EDO00619.1 - 1.1 9.7 5.6 3.1 8.2 3.9 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF3292 PF11696.3 EDO00621.1 - 3.3e-285 947.0 0.0 3.8e-285 946.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) SUR7 PF06687.7 EDO00622.1 - 3.1e-22 79.2 6.2 3.8e-22 78.8 4.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1616 PF07760.6 EDO00622.1 - 0.0093 15.1 0.9 0.014 14.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) DUF4389 PF14333.1 EDO00622.1 - 0.018 14.7 3.8 0.021 14.5 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4389) Thyroglobulin_1 PF00086.13 EDO00622.1 - 0.073 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat DUF202 PF02656.10 EDO00622.1 - 5.1 7.3 10.4 4.2 7.6 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Glyco_hydro_76 PF03663.9 EDO00627.1 - 2.1e-140 468.3 24.9 3e-140 467.8 17.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EDO00627.1 - 0.0094 15.0 11.7 0.028 13.4 0.6 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 gag-asp_proteas PF13975.1 EDO00630.1 - 6.3e-16 57.9 0.1 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 EDO00630.1 - 2.7e-15 56.5 0.0 8.2e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 EDO00630.1 - 7.7e-11 42.3 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDO00630.1 - 4.1e-09 36.3 0.1 2.9e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO00630.1 - 1.9e-06 27.5 2.6 3.4e-06 26.7 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 EDO00630.1 - 3.5e-06 26.5 0.0 6.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EDO00630.1 - 4e-05 23.5 0.0 7.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDO00630.1 - 0.00066 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_5 PF14787.1 EDO00630.1 - 0.11 11.9 9.4 0.027 13.9 4.1 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF3443 PF11925.3 EDO00630.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) HELP PF03451.9 EDO00632.1 - 0.072 12.6 0.1 5.9 6.4 0.0 2.1 1 1 1 2 2 2 0 HELP motif WD40 PF00400.27 EDO00633.1 - 5.7e-10 38.6 0.1 1.9e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat TPR_10 PF13374.1 EDO00634.1 - 2e-40 135.5 4.7 2.2e-14 52.8 0.0 5.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDO00634.1 - 2.2e-26 91.5 0.0 6.3e-12 45.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO00634.1 - 2e-09 36.4 0.1 0.0066 16.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO00634.1 - 5.3e-06 26.2 0.1 0.27 11.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO00634.1 - 1.7e-05 24.2 0.0 0.68 9.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO00634.1 - 2.7e-05 23.7 0.0 0.12 12.0 0.0 2.9 2 2 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO00634.1 - 7.1e-05 22.4 0.3 1.2 9.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO00634.1 - 0.00034 20.9 0.0 2.7 8.3 0.0 3.8 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDO00634.1 - 0.00061 19.9 0.0 4.9 7.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO00634.1 - 0.0022 18.6 0.0 4.2 8.1 0.0 3.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO00634.1 - 0.003 18.0 0.1 11 6.9 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Rab5-bind PF09311.6 EDO00634.1 - 0.027 14.3 0.0 1.3 8.8 0.0 3.0 1 1 2 3 3 3 0 Rabaptin-like protein TPR_8 PF13181.1 EDO00634.1 - 0.15 11.9 0.0 9.7 6.2 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 EDO00635.1 - 1.1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO00635.1 - 0.00033 20.7 0.0 0.00057 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EDO00635.1 - 0.00047 19.1 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Cupin_3 PF05899.7 EDO00635.1 - 0.0023 17.2 0.1 0.007 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Arch_ATPase PF01637.13 EDO00635.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDO00635.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.4 EDO00635.1 - 0.05 12.2 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 EDO00635.1 - 0.079 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ArgK PF03308.11 EDO00635.1 - 0.088 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF463 PF04317.7 EDO00635.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Ferritin_2 PF13668.1 EDO00637.1 - 2.8e-42 143.8 4.6 4.1e-42 143.3 3.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain RasGEF PF00617.14 EDO00640.1 - 1.5e-62 210.6 0.0 2.8e-62 209.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDO00640.1 - 3e-25 88.3 0.1 9.9e-25 86.6 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EDO00640.1 - 6.3e-16 57.5 0.1 1.2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO00640.1 - 5.4e-13 48.3 0.8 1.1e-12 47.3 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EDO00640.1 - 8.5e-13 47.5 0.1 1.6e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EDO00640.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 WW domain Viral_Beta_CD PF04530.7 EDO00640.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family Nucleoplasmin PF03066.10 EDO00640.1 - 7 6.1 8.2 14 5.1 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin TSP_1 PF00090.14 EDO00641.1 - 0.17 12.0 0.7 0.21 11.7 0.5 1.3 1 1 0 1 1 1 0 Thrombospondin type 1 domain Fungal_trans PF04082.13 EDO00642.1 - 3e-17 62.3 3.4 5.3e-17 61.5 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EDO00642.1 - 7.7e-09 35.4 12.2 1.7e-05 24.8 4.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO00642.1 - 6.8e-05 22.9 13.0 0.0041 17.3 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO00642.1 - 0.00025 21.2 14.7 0.035 14.4 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 EDO00643.1 - 1e-05 24.8 0.2 1e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Spb1_C PF07780.7 EDO00644.1 - 6.2e-75 251.3 24.0 6.2e-75 251.3 16.6 3.2 1 1 2 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EDO00645.1 - 1.3e-55 188.2 0.0 1.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EDO00645.1 - 1.6e-37 128.4 0.0 2.4e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.1 EDO00645.1 - 0.023 14.4 0.0 0.088 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO00645.1 - 0.028 15.0 0.0 0.3 11.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EDO00646.1 - 7.7e-21 73.1 9.4 5.5e-05 22.8 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Cupin_8 PF13621.1 EDO00647.1 - 1.2e-33 116.6 0.0 3.9e-32 111.7 0.0 2.0 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.7 EDO00647.1 - 9.8e-09 34.8 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein S1 PF00575.18 EDO00649.1 - 9.2e-90 294.7 42.9 4e-14 52.4 1.2 12.9 13 0 0 13 13 13 12 S1 RNA binding domain TPR_19 PF14559.1 EDO00649.1 - 1.2e-07 31.9 0.0 0.033 14.5 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO00649.1 - 3.9e-07 30.1 0.1 0.56 10.9 0.0 5.6 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO00649.1 - 4.2e-05 24.0 0.0 0.073 13.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EDO00649.1 - 0.0008 19.2 0.1 1.3 8.7 0.0 3.6 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EDO00649.1 - 0.0091 15.6 0.0 0.29 10.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_15 PF13429.1 EDO00649.1 - 0.0093 15.0 0.8 0.018 14.1 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO00649.1 - 0.049 14.1 1.0 0.74 10.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO00649.1 - 0.12 12.3 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat EXOSC1 PF10447.4 EDO00649.1 - 9.9 6.1 11.7 8.6 6.4 0.3 5.9 8 1 0 8 8 8 0 Exosome component EXOSC1/CSL4 Tim17 PF02466.14 EDO00650.1 - 0.14 12.1 3.2 1.2 9.1 2.2 2.1 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_6 PF14259.1 EDO00651.1 - 1.7e-10 40.7 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO00651.1 - 7.9e-09 35.0 0.1 7.9e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00651.1 - 8.2e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med8 PF10232.4 EDO00651.1 - 0.31 10.5 4.9 0.48 9.9 3.4 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Mitofilin PF09731.4 EDO00651.1 - 2.5 6.6 15.4 3.3 6.2 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PBP_sp32 PF07222.7 EDO00651.1 - 6.9 5.7 8.3 11 5.0 5.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DOT1 PF08123.8 EDO00653.1 - 2e-26 92.5 0.0 3.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 ATG16 PF08614.6 EDO00654.1 - 1.9e-40 138.8 23.5 2.1e-40 138.6 16.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EDO00654.1 - 0.0061 16.0 10.9 0.011 15.1 7.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF4600 PF15372.1 EDO00654.1 - 0.094 12.9 14.0 0.037 14.2 7.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) V_ATPase_I PF01496.14 EDO00654.1 - 3.2 5.5 6.7 3.8 5.2 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EDO00654.1 - 5.3 7.1 10.5 4.4 7.4 5.9 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ras PF00071.17 EDO00655.1 - 6.6e-56 188.1 0.1 7.7e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO00655.1 - 6.3e-19 68.6 0.0 9.4e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO00655.1 - 7.1e-13 48.1 0.0 8.2e-13 47.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO00655.1 - 3e-07 30.3 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO00655.1 - 6.7e-07 28.6 0.0 8.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO00655.1 - 1.1e-06 28.1 0.0 3.8e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EDO00655.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDO00655.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EDO00655.1 - 0.0043 16.6 0.2 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EDO00655.1 - 0.0044 16.5 0.3 0.16 11.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EDO00655.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EDO00655.1 - 0.0053 16.2 0.1 0.097 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EDO00655.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EDO00655.1 - 0.0083 15.5 0.2 0.0095 15.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EDO00655.1 - 0.0084 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EDO00655.1 - 0.009 15.4 0.0 0.043 13.2 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EDO00655.1 - 0.014 14.4 0.3 0.04 12.9 0.0 1.9 3 0 0 3 3 3 0 Septin AAA_16 PF13191.1 EDO00655.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EDO00655.1 - 0.024 14.3 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EDO00655.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EDO00655.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain EamA PF00892.15 EDO00656.1 - 4.8e-12 46.0 24.7 2.4e-09 37.3 1.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EDO00656.1 - 6.2e-10 38.4 6.0 1.1e-09 37.6 4.1 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO00656.1 - 2e-08 34.0 20.5 7.1e-06 25.7 0.5 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 EDO00656.1 - 5.5e-07 28.7 11.3 1.4e-06 27.4 5.0 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EDO00656.1 - 7.6e-06 26.1 3.6 7.6e-06 26.1 2.5 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EDO00656.1 - 0.018 14.1 4.0 0.26 10.3 3.5 2.2 1 1 1 2 2 2 0 Nucleotide-sugar transporter UPF0546 PF10639.4 EDO00656.1 - 4.2 7.2 13.1 2 8.2 1.4 3.0 3 1 0 3 3 3 0 Uncharacterised protein family UPF0546 Metallophos PF00149.23 EDO00657.1 - 3.4e-10 39.6 0.7 1.5e-09 37.5 0.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO00657.1 - 1.3e-08 34.8 0.2 2.3e-08 34.0 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF413 PF04219.7 EDO00657.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Heme_oxygenase PF01126.15 EDO00662.1 - 2.7e-14 53.2 0.0 4.7e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase DUF2422 PF10337.4 EDO00663.1 - 4.7e-55 187.1 0.0 4.7e-55 187.1 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EDO00663.1 - 7.9e-20 71.0 15.8 1.9e-19 69.8 10.6 2.0 1 1 0 1 1 1 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EDO00663.1 - 2.1e-09 37.3 0.0 4.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EDO00663.1 - 0.027 14.3 9.3 0.072 12.9 6.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Abhydrolase_6 PF12697.2 EDO00665.1 - 4.7e-23 82.2 0.0 8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO00665.1 - 4.4e-14 52.4 0.0 1.2e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EDO00665.1 - 1.5e-09 37.5 0.0 3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EDO00665.1 - 2.1e-07 30.7 0.0 8.3e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 EDO00665.1 - 0.00033 20.7 0.0 0.0007 19.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.8 EDO00665.1 - 0.0047 16.5 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.22 EDO00665.1 - 0.027 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2305 PF10230.4 EDO00665.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EDO00665.1 - 0.047 13.2 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.20 EDO00665.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EDO00665.1 - 0.23 11.6 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EDO00672.1 - 0.00033 20.3 0.3 0.0011 18.5 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EDO00672.1 - 0.011 15.5 0.4 0.023 14.4 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO00672.1 - 0.028 13.8 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 EDO00672.1 - 0.045 13.0 0.5 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDO00672.1 - 0.19 11.5 1.7 0.39 10.5 1.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_8 PF08022.7 EDO00674.1 - 2.2e-16 59.6 0.0 5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDO00674.1 - 8.6e-15 54.9 11.1 2.5e-14 53.4 7.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDO00674.1 - 3.3e-13 49.8 0.0 1.2e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4011 PF13195.1 EDO00674.1 - 0.19 11.7 0.1 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Cytomega_TRL10 PF06084.6 EDO00675.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Aldedh PF00171.17 EDO00676.1 - 7.5e-158 525.6 0.3 8.8e-158 525.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDO00676.1 - 0.0039 16.4 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GMC_oxred_N PF00732.14 EDO00678.1 - 6.8e-48 163.3 0.0 9.1e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO00678.1 - 3e-40 137.8 0.0 5.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDO00678.1 - 0.00024 20.1 0.0 0.0035 16.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDO00678.1 - 0.00029 19.8 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDO00678.1 - 0.00055 19.9 0.1 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO00678.1 - 0.0029 16.5 0.0 0.83 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EDO00678.1 - 0.0039 17.1 0.0 0.026 14.3 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDO00678.1 - 0.047 12.3 0.1 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Chs3p PF12271.3 EDO00679.1 - 7.2e-141 468.3 16.3 8.1e-141 468.1 11.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Cyclin PF08613.6 EDO00684.1 - 3.7e-16 59.8 0.1 1.4e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EDO00684.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gly_transf_sug PF04488.10 EDO00685.1 - 5.8e-14 52.3 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 EDO00686.1 - 3.5e-86 289.2 0.0 4.2e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO00686.1 - 4.5e-07 30.7 0.0 3.5e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_3 PF01764.20 EDO00687.1 - 1.4e-07 31.1 0.0 3.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EDO00687.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO00687.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EDO00687.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein IMS PF00817.15 EDO00691.1 - 1.3e-35 122.3 0.0 2.2e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDO00691.1 - 3.8e-14 52.7 0.0 7.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EDO00691.1 - 0.0031 17.4 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-DHHC PF01529.15 EDO00695.1 - 1.1e-07 31.4 1.7 1.7e-07 30.7 1.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4117 PF13491.1 EDO00695.1 - 0.14 11.5 2.6 0.23 10.8 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) COX4_pro_2 PF07835.7 EDO00695.1 - 1.7 8.6 9.0 0.089 12.7 1.1 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Terminase_3 PF04466.8 EDO00696.1 - 0.025 13.6 0.6 0.026 13.6 0.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit Pkinase PF00069.20 EDO00698.1 - 5.4e-58 196.1 0.0 7.1e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00698.1 - 1.3e-25 89.9 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO00698.1 - 1.4e-05 24.2 0.0 3e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO00698.1 - 0.0035 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_int_SAM_1 PF02899.12 EDO00698.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Seadorna_VP7 PF07387.6 EDO00698.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 p450 PF00067.17 EDO00699.1 - 7.1e-28 97.3 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RHH_1 PF01402.16 EDO00700.1 - 0.00044 20.0 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family FlxA PF14282.1 EDO00700.1 - 0.0075 16.2 1.2 0.011 15.7 0.8 1.2 1 0 0 1 1 1 1 FlxA-like protein Cluap1 PF10234.4 EDO00700.1 - 0.031 13.4 0.1 0.032 13.4 0.1 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 RepB-RCR_reg PF10723.4 EDO00700.1 - 0.034 13.8 0.3 0.054 13.2 0.2 1.3 1 1 0 1 1 1 0 Replication regulatory protein RepB SR-25 PF10500.4 EDO00700.1 - 0.06 12.8 0.1 0.067 12.6 0.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_assoc PF14363.1 EDO00700.1 - 0.098 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA MscS_porin PF12795.2 EDO00700.1 - 0.15 11.3 1.4 0.18 11.0 1.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Glyoxalase_2 PF12681.2 EDO00701.1 - 4.3e-06 27.2 0.0 1.6e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EDO00701.1 - 0.0083 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PTPLA PF04387.9 EDO00704.1 - 3.7e-52 176.0 11.9 3.7e-52 176.0 8.2 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA CNH PF00780.17 EDO00705.1 - 1.2e-83 280.6 0.0 3.8e-83 279.0 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EDO00705.1 - 1.1e-46 158.1 0.0 2.1e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EDO00705.1 - 7.3e-37 126.9 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EDO00705.1 - 4.8e-15 55.0 0.0 9.6e-15 54.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EDO00705.1 - 0.0029 17.7 0.0 0.025 14.8 0.0 2.6 2 1 0 2 2 2 1 PH domain ATP-synt_C PF00137.16 EDO00706.1 - 1.4e-24 85.7 24.9 5.8e-15 54.9 6.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Asp PF00026.18 EDO00708.1 - 2.5e-69 233.9 13.9 3e-69 233.7 9.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDO00708.1 - 1.8e-06 28.3 1.8 0.00016 22.0 0.4 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 EDO00708.1 - 2.9e-06 27.3 1.5 2.9e-05 24.0 0.0 2.9 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDO00708.1 - 8.4e-05 22.1 0.0 0.00027 20.5 0.0 1.9 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ACT PF01842.20 EDO00710.1 - 0.13 11.8 0.2 5.2 6.6 0.0 2.7 2 0 0 2 2 2 0 ACT domain Retrotrans_gag PF03732.12 EDO00710.1 - 1.5 8.9 10.4 2.9 8.0 5.3 3.1 2 1 0 2 2 2 0 Retrotransposon gag protein DUF4336 PF14234.1 EDO00711.1 - 3.8e-16 59.1 0.2 8.9e-12 44.7 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) MBD_C PF14048.1 EDO00715.1 - 0.33 11.5 3.2 2.4 8.7 0.1 2.4 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 AAA PF00004.24 EDO00716.1 - 1.1e-97 323.3 0.0 5.7e-48 162.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDO00716.1 - 1.5e-20 72.9 0.8 4.8e-20 71.2 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EDO00716.1 - 6.6e-14 52.1 0.0 2.3e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EDO00716.1 - 4.4e-13 49.3 0.0 2.6e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EDO00716.1 - 5.8e-13 48.4 0.0 2.3e-05 23.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO00716.1 - 1.7e-11 43.9 0.8 4.1e-06 26.5 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO00716.1 - 2.4e-11 43.8 0.3 0.0022 18.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO00716.1 - 3.1e-11 44.1 0.0 0.00069 20.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO00716.1 - 2.7e-10 40.5 0.0 0.0011 19.0 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EDO00716.1 - 4.1e-09 35.6 0.0 0.0013 17.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EDO00716.1 - 8e-08 31.9 5.2 0.06 12.7 0.0 4.6 3 2 1 5 5 4 2 AAA domain IstB_IS21 PF01695.12 EDO00716.1 - 8.8e-08 31.7 0.2 0.012 15.0 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EDO00716.1 - 1.5e-07 31.3 0.0 0.0061 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EDO00716.1 - 1.8e-07 30.6 0.0 4.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 EDO00716.1 - 3.1e-07 29.6 0.0 0.0049 15.9 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EDO00716.1 - 4.5e-07 29.2 0.2 0.031 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EDO00716.1 - 4.6e-07 29.4 1.9 0.014 15.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EDO00716.1 - 2.2e-06 27.7 0.0 0.031 14.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 EDO00716.1 - 2.6e-06 26.7 0.7 0.52 9.3 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EDO00716.1 - 4.2e-06 27.0 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EDO00716.1 - 1.2e-05 25.2 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 EDO00716.1 - 1.2e-05 24.3 0.0 0.01 14.7 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EDO00716.1 - 1.7e-05 24.8 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EDO00716.1 - 2.4e-05 24.0 0.3 0.13 11.8 0.0 3.2 4 0 0 4 4 2 2 AAA domain Sigma54_activ_2 PF14532.1 EDO00716.1 - 2.9e-05 24.1 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EDO00716.1 - 2.9e-05 23.6 0.0 0.29 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EDO00716.1 - 3.8e-05 23.0 0.2 0.31 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 EDO00716.1 - 4.2e-05 23.8 0.0 0.27 11.5 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 EDO00716.1 - 6.9e-05 21.8 0.0 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EDO00716.1 - 9.1e-05 22.2 0.0 5.5 6.6 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Vps4_C PF09336.5 EDO00716.1 - 0.00013 21.7 0.1 0.00065 19.5 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EDO00716.1 - 0.0004 19.9 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EDO00716.1 - 0.0006 19.4 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EDO00716.1 - 0.00076 19.1 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 EDO00716.1 - 0.00084 18.9 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDO00716.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EDO00716.1 - 0.0012 17.8 0.0 0.48 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EDO00716.1 - 0.0028 17.4 1.1 1 9.0 0.0 4.2 5 0 0 5 5 3 1 NTPase NB-ARC PF00931.17 EDO00716.1 - 0.0032 16.3 0.1 0.57 8.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EDO00716.1 - 0.0047 16.4 0.0 0.56 9.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EDO00716.1 - 0.013 14.6 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EDO00716.1 - 0.026 13.5 0.0 1 8.2 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain SKI PF01202.17 EDO00716.1 - 0.043 13.6 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_10 PF12846.2 EDO00716.1 - 0.049 13.0 0.7 10 5.4 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain KTI12 PF08433.5 EDO00716.1 - 0.069 12.3 0.3 19 4.3 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 UFD1 PF03152.9 EDO00716.1 - 0.078 12.1 0.0 4.3 6.4 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 eIF-1a PF01176.14 EDO00716.1 - 0.098 12.0 0.5 1.1 8.7 0.1 2.6 1 1 2 3 3 3 0 Translation initiation factor 1A / IF-1 Zot PF05707.7 EDO00716.1 - 0.12 11.7 0.2 30 4.0 0.1 3.6 3 2 0 3 3 3 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 EDO00716.1 - 0.13 11.8 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pyr_redox_2 PF07992.9 EDO00717.1 - 1.2e-27 97.1 0.0 1.9e-26 93.1 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO00717.1 - 8.2e-15 54.9 0.0 5.6e-12 45.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO00717.1 - 2.6e-05 24.3 0.3 0.028 14.4 0.1 3.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EDO00717.1 - 0.088 13.0 0.4 4.3 7.6 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 EDO00718.1 - 4.4e-08 33.0 0.0 7e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO00718.1 - 7.2e-07 29.2 0.0 2.1e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO00718.1 - 2.1e-06 27.5 0.0 0.014 15.2 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO00718.1 - 4.9e-06 26.6 0.0 1.2e-05 25.3 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO00718.1 - 2.5e-05 23.9 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EDO00718.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EDO00718.1 - 0.0034 17.2 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SHOCT PF09851.4 EDO00719.1 - 0.19 11.2 0.3 0.32 10.5 0.2 1.4 1 0 0 1 1 1 0 Short C-terminal domain Herpes_LMP1 PF05297.6 EDO00719.1 - 3.5 6.4 6.2 6.1 5.6 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TMEM247 PF15444.1 EDO00720.1 - 0.053 13.3 0.3 0.09 12.5 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 SAM_2 PF07647.12 EDO00721.1 - 5.7e-15 54.9 0.0 1.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EDO00721.1 - 6.5e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EDO00721.1 - 2.2e-12 46.9 0.0 3.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EDO00722.1 - 0.0069 15.7 0.0 0.019 14.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Thr_synth_N PF14821.1 EDO00722.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Threonine synthase N terminus PalH PF08733.5 EDO00724.1 - 2e-110 368.9 0.0 3.7e-110 368.0 0.0 1.4 1 1 0 1 1 1 1 PalH/RIM21 DUF418 PF04235.7 EDO00724.1 - 1.9 8.1 9.1 1.8 8.1 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF418) TRAM_LAG1_CLN8 PF03798.11 EDO00725.1 - 8.4e-32 110.3 14.3 8.4e-32 110.3 9.9 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EDO00725.1 - 2.1e-22 78.3 0.0 5.3e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein ABC_tran PF00005.22 EDO00728.1 - 3.5e-34 118.0 0.0 1e-33 116.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDO00728.1 - 2.9e-22 79.3 6.1 4.1e-14 52.6 1.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDO00728.1 - 2e-07 30.4 0.2 1.9e-06 27.2 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO00728.1 - 0.00025 21.0 0.1 0.015 15.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDO00728.1 - 0.0019 17.4 0.0 0.0044 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDO00728.1 - 0.0058 16.5 2.7 0.018 14.9 0.2 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EDO00728.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EDO00728.1 - 0.027 13.9 0.2 0.087 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO00728.1 - 0.042 13.9 0.2 0.25 11.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain COX5B PF01215.14 EDO00729.1 - 3.3e-38 130.4 0.0 4.2e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EDO00729.1 - 0.012 15.1 1.0 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger RVT_1 PF00078.22 EDO00731.1 - 8.9e-23 80.7 0.0 2.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO00731.1 - 1.3e-10 41.4 0.0 8e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EDO00731.1 - 4.9e-07 29.0 0.1 9.7e-07 28.1 0.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EDO00731.1 - 2.2e-05 24.8 0.0 4.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 EDO00731.1 - 5.4e-05 22.7 0.1 0.00017 21.1 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APG6 PF04111.7 EDO00731.1 - 0.04 12.9 2.2 0.17 10.8 0.4 2.5 3 0 0 3 3 3 0 Autophagy protein Apg6 Retrotrans_gag PF03732.12 EDO00731.1 - 0.22 11.5 2.5 0.43 10.6 0.2 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein Cortex-I_coil PF09304.5 EDO00731.1 - 0.58 10.2 8.5 0.32 11.0 3.2 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil Myb_DNA-bind_6 PF13921.1 EDO00732.1 - 1.1e-16 60.5 0.3 7.2e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO00732.1 - 5.8e-12 45.4 1.8 6.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EDO00732.1 - 0.013 15.6 1.2 0.11 12.7 0.5 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 EDO00732.1 - 0.09 12.9 1.5 0.31 11.1 0.7 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PRP8_domainIV PF12134.3 EDO00734.1 - 5e-113 376.1 1.1 8.5e-113 375.3 0.8 1.3 1 0 0 1 1 1 1 PRP8 domain IV core PROCT PF08084.6 EDO00734.1 - 2.2e-05 24.1 0.1 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain OCD_Mu_crystall PF02423.10 EDO00734.1 - 0.025 13.3 1.1 0.044 12.5 0.8 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PROCN PF08083.6 EDO00735.1 - 3.3e-224 743.8 9.0 3.3e-224 743.8 6.2 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRO8NT PF08082.6 EDO00735.1 - 9.4e-78 259.1 2.0 2.2e-77 257.8 0.5 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EDO00735.1 - 1.6e-66 222.0 0.1 3.3e-66 221.0 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EDO00735.1 - 2.4e-44 149.0 0.1 5.7e-44 147.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 U6-snRNA_bdg PF10596.4 EDO00735.1 - 2.1e-33 114.9 0.1 5.4e-33 113.6 0.1 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 DUF3753 PF12575.3 EDO00735.1 - 0.078 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 EDO00736.1 - 2.2e-38 130.3 3.5 3e-38 129.9 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EDO00736.1 - 0.64 9.7 4.6 8.2 6.1 0.1 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Alk_phosphatase PF00245.15 EDO00737.1 - 7.7e-107 357.5 0.0 9.4e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EDO00737.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EDO00737.1 - 0.0028 17.3 0.1 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Anti-sigma-K factor rskA SQS_PSY PF00494.14 EDO00738.1 - 1.2e-24 87.0 0.0 1.6e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EDO00739.1 - 6e-69 232.1 0.0 9.1e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDO00739.1 - 9.7e-26 89.7 0.0 2e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EDO00739.1 - 9.3e-14 51.0 0.0 2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EDO00739.1 - 1.6e-06 28.0 8.9 3.1e-06 27.1 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO00739.1 - 3e-05 23.5 9.3 5.6e-05 22.7 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EDO00739.1 - 0.00033 20.5 0.0 0.0013 18.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EDO00739.1 - 0.0007 19.2 5.9 0.0014 18.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO00739.1 - 0.0013 18.5 8.0 0.0025 17.5 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.1 EDO00739.1 - 0.0098 15.4 0.1 0.032 13.7 0.1 1.9 1 0 0 1 1 1 1 UBA-like domain zf-RING_5 PF14634.1 EDO00739.1 - 0.024 14.3 7.8 0.054 13.2 5.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDO00739.1 - 5 7.0 7.9 11 5.9 5.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PAN_1 PF00024.21 EDO00741.1 - 3.4e-05 23.5 1.3 0.00015 21.4 0.9 2.1 1 0 0 1 1 1 1 PAN domain MAT_Alpha1 PF04769.7 EDO00741.1 - 0.086 12.1 1.9 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 PAN_4 PF14295.1 EDO00741.1 - 0.26 11.0 5.1 0.63 9.7 3.5 1.6 1 0 0 1 1 1 0 PAN domain ThiF PF00899.16 EDO00742.1 - 6.1e-36 123.2 0.0 1.1e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 EDO00742.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 EDO00742.1 - 0.025 14.5 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 EDO00742.1 - 0.047 13.1 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyoxalase_2 PF12681.2 EDO00743.1 - 2.4e-10 40.9 0.0 3.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EDO00743.1 - 4.1e-09 36.4 0.0 6.5e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EDO00743.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDO00743.1 - 0.0015 18.4 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain adh_short_C2 PF13561.1 EDO00747.1 - 2.7e-16 60.0 0.0 3.2e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1620 PF07774.8 EDO00748.1 - 5.4e-74 248.1 0.0 8.8e-74 247.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EDO00748.1 - 6.9e-20 71.5 9.1 1e-16 61.1 2.0 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EDO00748.1 - 4.5e-07 29.0 4.4 0.0044 16.5 0.0 4.8 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.1 EDO00748.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.6 5 0 0 5 5 5 0 PQQ-like domain DUF3121 PF11319.3 EDO00748.1 - 0.18 11.2 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) LDB19 PF13002.2 EDO00749.1 - 9e-46 155.7 0.2 2.6e-45 154.3 0.1 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EDO00749.1 - 5.9e-10 39.1 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Dehydrin PF00257.14 EDO00750.1 - 0.1 12.9 1.9 0.12 12.6 1.3 1.1 1 0 0 1 1 1 0 Dehydrin PI3_PI4_kinase PF00454.22 EDO00751.1 - 5.8e-44 150.3 0.0 1.6e-43 148.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EDO00751.1 - 2e-37 128.3 0.5 9.7e-37 126.0 0.0 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EDO00751.1 - 8.3e-12 44.3 0.7 3e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 FATC domain DUF3414 PF11894.3 EDO00752.1 - 0 1080.3 21.1 1.9e-162 542.2 3.5 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3414) Cullin PF00888.17 EDO00753.1 - 6.9e-119 398.0 1.0 1e-118 397.5 0.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDO00753.1 - 1.8e-27 94.9 0.6 6e-27 93.2 0.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_34 PF13601.1 EDO00753.1 - 0.046 13.7 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.1 EDO00753.1 - 0.047 13.0 0.1 2.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EDO00753.1 - 0.068 12.8 0.0 5.7 6.6 0.0 3.2 3 0 0 3 3 3 0 MarR family DUF1212 PF06738.7 EDO00754.1 - 0.21 11.0 2.6 0.23 10.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Milton PF12448.3 EDO00755.1 - 0.54 10.4 13.9 0.28 11.3 8.3 1.5 1 1 0 1 1 1 0 Kinesin associated protein DUF566 PF04484.7 EDO00755.1 - 0.6 9.5 12.7 0.87 9.0 8.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF566) GPI-anchored PF10342.4 EDO00757.1 - 3.3e-15 56.3 2.4 3.3e-15 56.3 1.6 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF515 PF04415.7 EDO00757.1 - 2 6.5 15.5 2.4 6.2 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.4 EDO00757.1 - 3.1 5.9 9.4 3.5 5.7 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4231 PF14015.1 EDO00760.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RhoGAP PF00620.22 EDO00761.1 - 7.2e-09 35.4 0.0 1.5e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 RhoGAP domain CBS PF00571.23 EDO00762.1 - 1.8e-25 88.4 7.1 3.3e-11 42.7 0.0 3.9 4 0 0 4 4 4 3 CBS domain Arm PF00514.18 EDO00763.1 - 7.9e-68 222.1 33.5 3.4e-13 48.8 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDO00763.1 - 1.8e-24 85.8 14.4 5.7e-07 29.7 0.5 7.6 2 1 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EDO00763.1 - 1.9e-19 67.9 15.3 0.022 14.7 0.1 9.6 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EDO00763.1 - 3.9e-16 58.9 15.6 0.0022 18.4 0.1 8.1 6 2 3 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 EDO00763.1 - 1.6e-12 46.5 10.3 1.1e-08 33.9 0.2 3.0 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EDO00763.1 - 3.6e-11 42.6 8.6 0.0052 15.9 1.8 3.6 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EDO00763.1 - 4.2e-10 39.2 3.3 0.00097 18.3 0.1 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EDO00763.1 - 1.5e-08 33.0 3.3 2.8e-08 32.1 2.3 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_PBS PF03130.11 EDO00763.1 - 0.0026 18.0 8.9 4.5 8.0 0.8 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO00763.1 - 0.0051 17.1 0.5 0.58 10.5 0.1 3.5 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 EDO00763.1 - 0.029 13.3 0.5 0.099 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Vpu PF00558.14 EDO00763.1 - 0.089 12.3 2.6 0.1 12.1 0.5 2.1 2 0 0 2 2 2 0 Vpu protein V-ATPase_H_C PF11698.3 EDO00763.1 - 0.095 12.6 8.9 14 5.6 0.0 4.8 2 1 3 6 6 6 0 V-ATPase subunit H ParcG PF10274.4 EDO00763.1 - 0.23 11.3 3.1 8.5 6.2 0.0 3.7 4 0 0 4 4 4 0 Parkin co-regulated protein IF3_C PF00707.17 EDO00764.1 - 1.6e-12 46.9 0.8 2.8e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EDO00764.1 - 8e-09 35.1 2.3 3e-06 26.7 0.9 2.2 1 1 1 2 2 2 2 Mitochondrial translation initiation factor Glypican PF01153.14 EDO00764.1 - 0.28 9.7 1.1 0.36 9.3 0.7 1.2 1 0 0 1 1 1 0 Glypican MARVEL PF01284.18 EDO00768.1 - 1.3e-05 25.0 11.1 8.4e-05 22.4 7.1 1.9 1 1 1 2 2 2 1 Membrane-associating domain PTPS_related PF10131.4 EDO00768.1 - 0.0071 14.5 2.8 0.0086 14.2 1.9 1.0 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein VIT1 PF01988.14 EDO00768.1 - 0.13 11.7 2.5 0.1 12.0 1.0 1.4 1 1 0 1 1 1 0 VIT family Dpy19 PF10034.4 EDO00768.1 - 0.32 9.1 2.5 0.4 8.8 1.7 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation PgaD PF13994.1 EDO00768.1 - 2 7.8 6.6 1.4 8.4 3.4 1.6 1 1 1 2 2 2 0 PgaD-like protein Gas_vesicle_C PF01304.12 EDO00769.1 - 8.4 6.1 8.0 23 4.7 0.1 2.1 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain MFS_1 PF07690.11 EDO00773.1 - 4.5e-29 101.2 53.9 1.7e-28 99.3 36.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP PF01161.15 EDO00774.1 - 1.4e-12 47.7 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SPAM PF02090.10 EDO00774.1 - 0.79 9.7 7.0 1.3 8.9 4.9 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Ribosomal_L4 PF00573.17 EDO00775.1 - 1.6e-49 167.9 0.0 1.9e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rep_fac-A_3 PF08661.6 EDO00777.1 - 5e-24 84.3 0.0 5.6e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.22 EDO00778.1 - 1.6e-05 24.1 9.2 0.0016 17.7 3.2 2.6 2 0 0 2 2 2 2 GATA zinc finger ECH_C PF13766.1 EDO00779.1 - 2.2e-32 111.6 1.1 1.8e-31 108.7 0.8 2.3 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EDO00779.1 - 7.8e-25 87.4 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family LSM PF01423.17 EDO00780.1 - 9.7e-18 63.4 0.0 1.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.12 EDO00781.1 - 6.9e-115 383.0 5.9 1e-114 382.5 4.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EDO00781.1 - 7e-44 149.5 0.7 1.3e-43 148.6 0.5 1.5 1 0 0 1 1 1 1 DAK2 domain EXOSC1 PF10447.4 EDO00782.1 - 9.6e-29 99.1 0.7 1.4e-28 98.6 0.5 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EDO00782.1 - 2.7e-15 55.3 0.2 6.3e-15 54.1 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EDO00782.1 - 0.021 14.9 0.2 0.48 10.5 0.1 2.6 1 1 1 2 2 2 0 S1 RNA binding domain OPT PF03169.10 EDO00783.1 - 1.1e-38 133.1 7.4 1.1e-37 129.8 1.1 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein VIT1 PF01988.14 EDO00783.1 - 4.3 6.7 4.9 8 5.8 3.4 1.4 1 0 0 1 1 1 0 VIT family OPT PF03169.10 EDO00784.1 - 2.9e-27 95.4 9.8 4.3e-26 91.5 6.2 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein Tat PF00539.13 EDO00786.1 - 0.014 14.9 1.7 0.023 14.3 1.2 1.4 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) EST1_DNA_bind PF10373.4 EDO00788.1 - 8.5e-17 61.2 0.1 1.6e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain CFEM PF05730.6 EDO00794.1 - 0.0014 18.3 3.5 0.0014 18.3 2.4 2.7 2 0 0 2 2 2 1 CFEM domain DUF427 PF04248.7 EDO00795.1 - 7.8e-23 79.9 1.3 7.2e-16 57.6 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Snf7 PF03357.16 EDO00796.1 - 2.4e-18 66.1 12.2 2.8e-18 65.8 8.5 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EDO00796.1 - 0.00019 20.8 2.3 0.0003 20.2 1.6 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF244 PF03112.9 EDO00796.1 - 0.14 11.6 3.8 0.18 11.3 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF Prominin PF05478.6 EDO00796.1 - 1 6.7 4.0 1.2 6.5 2.8 1.1 1 0 0 1 1 1 0 Prominin T2SM PF04612.7 EDO00796.1 - 5.8 6.6 7.2 1.9 8.2 0.0 2.3 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M DUF2296 PF10058.4 EDO00800.1 - 3.3e-20 71.5 0.1 5.6e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) GRIP PF01465.15 EDO00801.1 - 8.8e-13 47.5 0.4 1.9e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 EDO00801.1 - 0.00028 20.7 18.8 0.00028 20.7 13.0 12.2 3 2 7 11 11 11 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 EDO00801.1 - 0.0059 16.2 1.2 0.0059 16.2 0.8 10.8 10 0 0 10 10 10 2 Viral A-type inclusion protein repeat Myosin_tail_1 PF01576.14 EDO00801.1 - 0.0088 13.8 195.6 0.074 10.7 36.7 5.4 3 1 1 4 4 4 4 Myosin tail LPP PF04728.8 EDO00801.1 - 0.018 14.8 14.6 0.021 14.5 0.2 5.7 7 0 0 7 7 7 0 Lipoprotein leucine-zipper FlaC_arch PF05377.6 EDO00801.1 - 0.12 12.3 0.1 0.12 12.3 0.1 15.0 16 2 1 17 17 17 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EDO00801.1 - 1.2 8.2 73.6 0.46 9.6 3.2 8.9 2 2 6 9 9 9 0 Reovirus sigma C capsid protein Kelch_1 PF01344.20 EDO00802.1 - 5.8e-19 67.3 1.0 3.5e-07 29.6 0.1 5.3 4 2 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EDO00802.1 - 5.9e-19 67.3 9.5 3.1e-08 33.4 0.1 4.4 1 1 3 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EDO00802.1 - 2e-11 43.4 2.5 0.00017 21.3 0.0 4.5 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO00802.1 - 1.6e-10 40.7 0.2 0.00095 19.0 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 EDO00802.1 - 6e-08 32.6 2.4 0.003 17.6 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EDO00802.1 - 3e-06 26.7 0.1 0.53 10.1 0.0 4.6 3 2 0 3 3 3 2 Kelch motif Pkinase PF00069.20 EDO00803.1 - 1.6e-41 142.2 0.2 1.5e-24 86.5 0.1 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00803.1 - 8e-15 54.6 0.2 2e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SPX PF03105.14 EDO00803.1 - 0.073 12.8 8.4 0.063 13.0 0.8 2.1 2 0 0 2 2 2 0 SPX domain Brr6_like_C_C PF10104.4 EDO00804.1 - 1.3e-46 157.4 0.7 1.6e-46 157.1 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 EDO00805.1 - 1.7e-11 43.4 0.0 2.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HLH PF00010.21 EDO00806.1 - 1.9e-17 62.7 0.1 4.2e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 EDO00806.1 - 0.016 15.1 0.7 0.039 13.9 0.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EDO00806.1 - 0.037 13.8 0.9 0.037 13.8 0.6 1.8 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EDO00806.1 - 0.05 13.5 2.4 0.096 12.6 1.3 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 EDO00806.1 - 0.12 12.7 0.9 0.32 11.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Peptidase_S8 PF00082.17 EDO00808.1 - 7.8e-53 179.4 12.3 1.2e-52 178.7 8.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDO00808.1 - 3.9e-22 78.6 0.7 9.3e-22 77.3 0.2 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 Beach PF02138.13 EDO00811.1 - 2e-108 361.9 0.0 2.7e-108 361.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EDO00811.1 - 3.9e-11 42.7 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EDO00811.1 - 1.1e-08 34.5 2.7 0.00044 20.0 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Pectinesterase PF01095.14 EDO00812.1 - 1.1e-41 142.4 9.9 1.3e-41 142.0 6.8 1.1 1 0 0 1 1 1 1 Pectinesterase adh_short_C2 PF13561.1 EDO00816.1 - 1.4e-28 100.3 0.2 1.8e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO00816.1 - 6.7e-22 78.1 1.0 9.8e-22 77.6 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO00816.1 - 6.8e-12 45.4 0.5 1e-11 44.8 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EDO00816.1 - 0.027 14.1 0.4 0.45 10.1 0.6 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1752 PF08550.5 EDO00818.1 - 2.3e-10 39.8 4.1 4.6e-10 38.8 2.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_transf_90 PF05686.7 EDO00819.1 - 1.5e-12 46.9 2.1 3e-12 45.9 1.5 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 Ras PF00071.17 EDO00820.1 - 1.3e-38 131.9 0.0 6.4e-37 126.4 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO00820.1 - 1.4e-13 51.3 0.1 4.8e-13 49.6 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO00820.1 - 2.4e-05 23.6 0.0 0.00043 19.5 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EDO00820.1 - 0.001 19.1 0.3 0.26 11.4 0.0 2.7 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDO00820.1 - 0.0026 17.7 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain GTP_EFTU PF00009.22 EDO00820.1 - 0.017 14.5 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EDO00820.1 - 0.068 12.5 0.1 0.21 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 EDO00820.1 - 0.11 11.3 0.1 8.9 4.9 0.1 2.1 2 0 0 2 2 2 0 MCM2/3/5 family RRM_1 PF00076.17 EDO00822.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00822.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pex16 PF08610.5 EDO00823.1 - 1.5e-113 379.2 3.3 1.7e-113 379.0 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SWIRM PF04433.12 EDO00827.1 - 5.9e-16 58.3 0.0 1.6e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain DUF2614 PF11023.3 EDO00829.1 - 0.1 12.3 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) DUF914 PF06027.7 EDO00831.1 - 1.1e-104 349.9 22.9 1.5e-104 349.4 15.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EDO00831.1 - 0.0033 17.4 8.3 0.0033 17.4 5.7 2.6 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 EDO00831.1 - 0.066 12.1 21.6 0.092 11.6 14.9 1.1 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 EDO00831.1 - 0.2 11.2 25.4 1.1 8.8 6.8 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3272 PF11676.3 EDO00831.1 - 0.31 11.0 0.2 0.31 11.0 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3272) Abhydrolase_1 PF00561.15 EDO00832.1 - 1.9e-17 63.6 0.1 1.9e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO00832.1 - 1e-10 41.9 0.5 7.5e-10 39.0 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDO00832.1 - 1.2e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.4 EDO00832.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DDOST_48kD PF03345.9 EDO00834.1 - 1.9e-172 573.5 0.0 2.2e-172 573.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DAO PF01266.19 EDO00836.1 - 1.1e-23 83.7 0.1 1.2e-13 50.6 0.0 2.0 1 1 0 2 2 2 2 FAD dependent oxidoreductase adh_short PF00106.20 EDO00837.1 - 1.2e-29 103.3 0.0 1.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO00837.1 - 7.7e-15 55.3 0.0 9.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO00837.1 - 3.8e-09 36.4 0.0 6.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDO00837.1 - 1.8e-07 31.3 0.1 7.8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDO00837.1 - 0.0001 21.3 0.1 0.53 9.1 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EDO00837.1 - 0.00022 20.7 0.0 0.0063 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDO00837.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain CoA_binding_2 PF13380.1 EDO00837.1 - 0.013 15.6 0.1 0.028 14.5 0.0 1.5 2 0 0 2 2 2 0 CoA binding domain Eno-Rase_NADH_b PF12242.3 EDO00837.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 EDO00837.1 - 0.027 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EDO00837.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 EDO00837.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DLIC PF05783.6 EDO00838.1 - 5e-24 84.8 0.1 2.3e-20 72.7 0.0 3.8 4 0 0 4 4 4 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 EDO00839.1 - 1.8e-19 69.1 0.0 4.5e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00839.1 - 7.6e-15 54.6 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00839.1 - 1.2e-08 34.6 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3764 PF12594.3 EDO00839.1 - 0.0027 17.3 0.2 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3764) WD40 PF00400.27 EDO00840.1 - 8.1e-07 28.7 3.0 0.0069 16.2 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nbas_N PF15492.1 EDO00840.1 - 0.009 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 EDO00841.1 - 5.8e-106 353.6 0.0 1.3e-105 352.4 0.0 1.5 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EDO00841.1 - 0.00013 21.7 3.5 0.29 10.9 0.0 3.0 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EDO00841.1 - 0.00031 20.6 0.0 0.00076 19.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO00841.1 - 0.0077 15.4 0.2 0.021 13.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDO00841.1 - 0.018 14.4 0.0 0.42 10.0 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO00841.1 - 0.024 15.1 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein IIGP PF05049.8 EDO00841.1 - 0.067 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FMN_bind PF04205.9 EDO00841.1 - 0.12 12.5 0.4 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain V_ATPase_I PF01496.14 EDO00841.1 - 1.5 6.5 3.4 2 6.2 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_17 PF13207.1 EDO00841.1 - 1.7 9.4 6.2 1.2 9.9 0.2 2.8 2 2 0 2 2 2 0 AAA domain Bax1-I PF01027.15 EDO00842.1 - 2.1e-51 174.4 29.3 2.5e-51 174.2 20.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EDO00842.1 - 2 7.3 4.5 2.7 6.8 0.5 2.3 2 0 0 2 2 2 0 Orbivirus NS3 TRAM_LAG1_CLN8 PF03798.11 EDO00843.1 - 7.5e-32 110.4 22.0 7.5e-32 110.4 15.2 2.0 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EDO00843.1 - 1.4e-20 72.5 0.0 3.9e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein MFS_1 PF07690.11 EDO00844.1 - 2.4e-37 128.4 27.6 2e-33 115.5 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO00844.1 - 1.9e-08 33.3 7.8 2.5e-08 32.9 5.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EDO00844.1 - 0.00024 19.9 1.3 0.00042 19.1 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 EDO00844.1 - 0.0092 15.7 2.1 0.9 9.3 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family Abhydro_lipase PF04083.11 EDO00845.1 - 5e-21 73.8 0.1 1.1e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EDO00845.1 - 6e-16 58.6 1.3 4.2e-15 55.9 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EDO00845.1 - 0.12 11.8 0.1 17 4.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EDO00846.1 - 3.6e-28 97.3 3.2 4.6e-28 97.0 2.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EDO00846.1 - 0.0064 16.0 0.6 0.011 15.3 0.4 1.4 1 0 0 1 1 1 1 PAN-like domain Cmc1 PF08583.5 EDO00846.1 - 0.74 9.6 3.5 6.8 6.5 0.2 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_1 PF00170.16 EDO00847.1 - 3.7e-06 26.8 8.8 3.7e-06 26.8 6.1 2.1 2 1 1 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.12 EDO00847.1 - 0.0081 16.4 10.3 0.0081 16.4 7.1 2.2 1 1 0 2 2 2 1 bZIP Maf transcription factor Peptidase_S64 PF08192.6 EDO00847.1 - 0.04 12.2 3.8 0.047 12.0 2.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 HeLo PF14479.1 EDO00847.1 - 0.19 11.4 7.1 0.25 11.0 4.9 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Mnd1 PF03962.10 EDO00847.1 - 0.48 10.0 11.4 6.2 6.4 7.8 2.0 1 1 0 1 1 1 0 Mnd1 family Fungal_trans_2 PF11951.3 EDO00848.1 - 7.4e-06 24.8 0.0 0.038 12.5 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain ABC_tran PF00005.22 EDO00850.1 - 3.1e-38 131.1 0.0 6.5e-19 68.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO00850.1 - 1.4e-19 70.5 13.8 4.6e-16 59.0 2.1 2.7 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EDO00850.1 - 1.1e-10 41.1 0.9 0.0093 15.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO00850.1 - 1.5e-10 41.5 8.1 0.002 18.1 0.0 4.6 4 1 1 5 5 4 3 AAA domain AAA_16 PF13191.1 EDO00850.1 - 9.5e-08 32.2 0.1 0.01 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDO00850.1 - 1.5e-06 27.6 1.9 0.045 13.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDO00850.1 - 1.8e-05 24.6 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO00850.1 - 6.1e-05 22.2 0.2 0.084 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EDO00850.1 - 8.7e-05 22.3 0.1 0.12 12.0 0.0 2.6 2 1 0 2 2 2 2 Archaeal ATPase AAA_25 PF13481.1 EDO00850.1 - 0.00046 19.6 2.3 0.36 10.2 0.0 3.1 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EDO00850.1 - 0.00049 20.2 1.4 0.98 9.5 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDO00850.1 - 0.00072 19.0 7.0 1 8.7 0.1 3.5 4 0 0 4 4 3 2 AAA-like domain SbcCD_C PF13558.1 EDO00850.1 - 0.00078 19.3 0.0 0.87 9.5 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EDO00850.1 - 0.0017 18.0 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 EDO00850.1 - 0.0026 17.2 0.6 0.93 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EDO00850.1 - 0.0042 17.5 2.4 0.42 11.1 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_23 PF13476.1 EDO00850.1 - 0.0082 16.4 1.2 0.79 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO00850.1 - 0.01 14.7 0.3 0.94 8.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EDO00850.1 - 0.014 14.5 0.7 6.3 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Pox_A32 PF04665.7 EDO00850.1 - 0.021 14.1 4.4 0.76 9.0 0.2 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein MobB PF03205.9 EDO00850.1 - 0.023 14.4 1.7 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EDO00850.1 - 0.023 14.1 1.3 4.1 6.8 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EDO00850.1 - 0.027 14.3 8.5 0.1 12.4 0.2 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EDO00850.1 - 0.03 13.1 0.6 5.4 5.7 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.18 EDO00850.1 - 0.032 14.0 1.6 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EDO00850.1 - 0.042 13.7 0.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDO00850.1 - 0.06 13.6 0.3 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EDO00850.1 - 0.3 9.9 2.0 9.4 5.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) CAP PF00188.21 EDO00852.1 - 1.8e-16 60.7 5.8 2.8e-16 60.1 4.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.10 EDO00853.1 - 1.3e-69 233.0 0.0 2.3e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EDO00853.1 - 1.2e-09 37.9 0.0 2.9e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.9 EDO00853.1 - 3.8e-06 26.5 1.0 1.6e-05 24.4 0.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EDO00853.1 - 0.00027 20.0 1.3 1.7 7.6 0.0 3.9 2 1 2 4 4 4 1 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 EDO00853.1 - 0.0084 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_47 PF01532.15 EDO00853.1 - 0.06 11.9 0.6 0.19 10.3 0.2 1.9 2 1 0 2 2 2 0 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EDO00853.1 - 0.082 11.1 0.0 0.35 9.0 0.0 1.9 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DDE_1 PF03184.14 EDO00854.1 - 2e-34 118.6 0.0 3.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO00854.1 - 2e-10 40.0 0.0 3.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO00854.1 - 3e-06 26.9 0.0 1.1e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NUMOD1 PF07453.8 EDO00854.1 - 0.0067 16.2 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 NUMOD1 domain DUF3373 PF11853.3 EDO00854.1 - 0.086 11.3 0.7 0.16 10.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF3450 PF11932.3 EDO00854.1 - 0.19 10.9 0.1 0.19 10.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) MFS_1 PF07690.11 EDO00856.1 - 1.5e-19 69.9 3.9 2.1e-19 69.4 2.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO00856.1 - 0.0029 16.2 0.5 0.0051 15.4 0.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF605 PF04652.11 EDO00858.1 - 4.7 6.5 15.0 5.8 6.1 10.4 1.2 1 0 0 1 1 1 0 Vta1 like zinc_ribbon_2 PF13240.1 EDO00861.1 - 0.074 12.5 1.7 4.3 6.9 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain XPA_N PF01286.13 EDO00861.1 - 4.7 6.9 8.2 12 5.7 1.1 2.5 2 0 0 2 2 2 0 XPA protein N-terminal zf-C4pol PF14260.1 EDO00862.1 - 0.041 13.8 1.3 0.06 13.3 0.9 1.3 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EDO00862.1 - 0.29 10.9 4.1 0.4 10.5 2.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon DUF4559 PF15112.1 EDO00862.1 - 0.38 9.8 5.4 0.41 9.7 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HypA PF01155.14 EDO00862.1 - 0.4 10.3 3.1 0.48 10.1 2.1 1.3 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Nop10p PF04135.7 EDO00862.1 - 0.52 10.0 2.6 0.8 9.4 1.8 1.3 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family zf-C2H2_3 PF13878.1 EDO00862.1 - 1.9 8.1 4.9 16 5.1 3.4 2.2 1 1 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO APH PF01636.18 EDO00863.1 - 1.2e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDO00863.1 - 0.0013 17.4 0.1 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EDO00863.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RRM_1 PF00076.17 EDO00865.1 - 8.9e-59 195.0 0.0 1.2e-19 69.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00865.1 - 2.8e-43 145.7 0.0 7.7e-15 54.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO00865.1 - 4.3e-30 103.3 0.0 1.5e-11 43.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO00865.1 - 5.7e-05 22.8 0.0 0.014 15.1 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EDO00865.1 - 0.00077 19.3 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EDO00865.1 - 0.13 12.1 0.1 2 8.3 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif PIF1 PF05970.9 EDO00866.1 - 1.6e-60 205.0 0.4 5e-46 157.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EDO00866.1 - 1.7e-17 63.6 0.0 5.3e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO00866.1 - 4.7e-06 26.7 0.0 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain zf-CCHC PF00098.18 EDO00866.1 - 6.1e-06 25.9 2.3 1.1e-05 25.1 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle AAA_19 PF13245.1 EDO00866.1 - 7.6e-06 25.6 0.2 2.2e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDO00866.1 - 0.00012 22.1 0.0 0.00097 19.2 0.0 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EDO00866.1 - 0.00014 19.7 0.4 0.00099 16.9 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EDO00866.1 - 0.00045 20.4 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO00866.1 - 0.00064 19.7 0.3 0.0028 17.6 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EDO00866.1 - 0.00099 18.6 0.0 1.4 8.3 0.0 2.9 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EDO00866.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EDO00866.1 - 0.012 15.7 0.1 0.04 14.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.11 EDO00866.1 - 0.014 14.6 0.5 0.15 11.2 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_5 PF07728.9 EDO00866.1 - 0.016 14.9 0.4 0.31 10.7 0.3 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EDO00866.1 - 0.02 15.2 0.1 0.11 12.8 0.1 2.3 1 1 0 2 2 1 0 ABC transporter TrwB_AAD_bind PF10412.4 EDO00866.1 - 0.029 13.0 0.1 0.059 11.9 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 EDO00866.1 - 0.032 13.7 0.1 0.086 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCHC_3 PF13917.1 EDO00866.1 - 0.033 13.9 1.0 0.079 12.7 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle AAA_14 PF13173.1 EDO00866.1 - 0.047 13.5 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EDO00866.1 - 0.047 12.4 0.3 0.093 11.4 0.2 1.4 1 0 0 1 1 1 0 ArgK protein AAA_7 PF12775.2 EDO00866.1 - 0.057 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 MobB PF03205.9 EDO00866.1 - 0.065 12.9 0.2 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EDO00866.1 - 0.095 12.3 0.1 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 NTPase zf-CCHC_2 PF13696.1 EDO00866.1 - 0.1 12.1 0.5 0.22 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF87 PF01935.12 EDO00866.1 - 0.1 12.3 0.5 2.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 YjeF_N PF03853.10 EDO00867.1 - 4.6e-35 120.7 0.0 6.7e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus DNA_ligase_A_N PF04675.9 EDO00868.1 - 1.1e-32 113.3 0.0 6.7e-23 81.4 0.1 2.3 1 1 1 2 2 2 2 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EDO00868.1 - 4.5e-24 84.9 0.0 1.1e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EDO00868.1 - 2.3e-15 56.7 0.0 8.8e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EDO00868.1 - 1e-08 35.2 0.2 1.4e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PC4 PF02229.11 EDO00871.1 - 0.14 11.4 0.0 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Methyltransf_23 PF13489.1 EDO00872.1 - 4.4e-15 55.7 0.0 7.4e-15 55.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO00872.1 - 5.6e-09 36.3 0.0 9.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO00872.1 - 3.2e-08 34.1 0.0 4.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO00872.1 - 5.4e-08 33.1 0.0 8.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO00872.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO00872.1 - 7.1e-06 26.4 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EDO00872.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EDO00872.1 - 0.0037 17.2 0.0 0.006 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO00872.1 - 0.0072 15.4 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDO00872.1 - 0.011 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FmrO PF07091.6 EDO00872.1 - 0.02 13.8 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EDO00872.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.6 EDO00872.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 EDO00872.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EDO00872.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MAP65_ASE1 PF03999.7 EDO00873.1 - 8.7e-72 242.6 8.9 8.7e-72 242.6 6.2 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf-C4H2 PF10146.4 EDO00873.1 - 0.0038 17.2 2.8 0.0038 17.2 1.9 3.2 4 0 0 4 4 4 1 Zinc finger-containing protein JAB PF01398.16 EDO00874.1 - 6.2e-30 103.2 0.1 1e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDO00874.1 - 2.4e-06 27.0 0.0 4.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EDO00874.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) tRNA-synt_1c PF00749.16 EDO00875.1 - 6e-53 179.5 0.2 3.2e-38 131.1 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 EDO00876.1 - 1.4e-24 85.6 2.7 2.6e-24 84.7 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO00876.1 - 1.4e-10 40.9 0.7 9.2e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO00876.1 - 5e-05 23.2 9.5 9.3e-05 22.3 6.6 1.4 1 0 0 1 1 1 1 DnaJ central domain GCC2_GCC3 PF07699.8 EDO00876.1 - 0.25 10.9 5.4 0.44 10.1 3.7 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 Ribosomal_L32e PF01655.13 EDO00877.1 - 2.7e-48 162.5 1.6 2.7e-48 162.5 1.1 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 DUF3135 PF11333.3 EDO00878.1 - 0.027 14.6 0.2 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Sec2p PF06428.6 EDO00880.1 - 1.2e-08 34.7 6.2 1.2e-08 34.7 4.3 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 EDO00880.1 - 0.0013 18.7 6.2 0.091 12.7 0.5 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 Tup_N PF08581.5 EDO00880.1 - 0.22 11.7 5.1 0.48 10.6 0.4 2.3 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.6 EDO00880.1 - 0.44 9.1 11.3 0.29 9.7 2.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Caudo_TAP PF02413.12 EDO00880.1 - 1 9.5 6.7 0.69 10.0 1.3 2.2 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein ERM PF00769.14 EDO00880.1 - 1.1 8.7 13.0 0.47 9.9 0.3 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 EDO00880.1 - 1.2 8.7 11.5 1.4 8.4 1.4 2.1 2 0 0 2 2 2 0 IncA protein DUF3373 PF11853.3 EDO00880.1 - 1.3 7.4 8.6 0.17 10.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) ADIP PF11559.3 EDO00880.1 - 2.6 7.9 13.6 6.7 6.6 0.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EDO00880.1 - 7.7 6.0 8.7 3.8 7.0 1.2 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 EDO00880.1 - 9.4 4.5 8.4 1.3 7.3 1.0 2.0 2 0 0 2 2 2 0 AAA domain UPRTase PF14681.1 EDO00881.1 - 1.1e-76 256.6 0.0 1.4e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EDO00881.1 - 9.2e-06 25.3 0.0 2.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 EDO00881.1 - 0.0043 16.1 0.1 0.23 10.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI P5CR_dimer PF14748.1 EDO00881.1 - 0.023 14.7 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation PRTase_2 PF15609.1 EDO00881.1 - 0.15 11.3 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase CRCB PF02537.10 EDO00882.1 - 1.8e-30 105.1 17.4 6.9e-19 67.8 1.7 4.1 4 0 0 4 4 4 3 CrcB-like protein p450 PF00067.17 EDO00884.1 - 6.5e-29 100.7 0.0 9.2e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ArgJ PF01960.13 EDO00885.1 - 1.4e-122 408.8 0.0 1.6e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Peptidase_S28 PF05577.7 EDO00887.1 - 8.2e-52 176.2 7.2 3.2e-51 174.2 5.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 EDO00887.1 - 1.3e-05 23.8 0.8 1.9e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 PS-10 peptidase S37 Thioredoxin PF00085.15 EDO00888.1 - 3.3e-61 203.4 1.6 1.1e-29 102.1 0.1 2.5 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 EDO00888.1 - 1.2e-26 93.1 0.8 9.2e-26 90.3 0.2 2.4 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EDO00888.1 - 4.7e-21 75.0 0.3 2.6e-09 37.2 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO00888.1 - 8.1e-14 51.5 0.1 2.3e-05 24.4 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EDO00888.1 - 1.3e-13 50.7 0.0 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EDO00888.1 - 4.6e-10 39.2 1.3 0.00082 19.0 0.0 2.5 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_6 PF13848.1 EDO00888.1 - 5.7e-09 36.0 1.3 0.0039 17.0 0.0 3.6 2 2 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 EDO00888.1 - 1.1e-07 31.5 0.9 0.00085 18.8 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EDO00888.1 - 1.1e-06 28.2 0.2 0.00063 19.3 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 EDO00888.1 - 1e-05 25.2 0.1 0.042 13.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_4 PF13462.1 EDO00888.1 - 0.00028 20.9 4.5 0.66 9.9 0.1 4.3 3 2 2 5 5 5 1 Thioredoxin TraF PF13728.1 EDO00888.1 - 0.0035 16.8 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein DSBA PF01323.15 EDO00888.1 - 0.0072 15.9 2.2 5.7 6.4 0.1 4.1 3 1 1 4 4 4 1 DSBA-like thioredoxin domain DUF1910 PF08928.5 EDO00888.1 - 0.013 15.4 0.1 3.1 7.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Glutaredoxin PF00462.19 EDO00888.1 - 0.029 14.3 0.4 8.2 6.5 0.0 2.9 2 1 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.1 EDO00888.1 - 0.12 12.5 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain HSBP1 PF06825.7 EDO00889.1 - 2.1e-16 59.2 1.3 2.1e-16 59.2 0.9 1.5 2 0 0 2 2 2 1 Heat shock factor binding protein 1 DUF2884 PF11101.3 EDO00889.1 - 0.03 13.7 0.2 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Matrilin_ccoil PF10393.4 EDO00889.1 - 0.055 12.8 0.3 1.2 8.6 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1664 PF07889.7 EDO00889.1 - 0.068 12.9 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GTP_EFTU PF00009.22 EDO00891.1 - 1.8e-47 161.2 0.0 4.3e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDO00891.1 - 2.8e-15 55.9 0.0 6.4e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO00891.1 - 5.5e-09 36.0 0.0 1.5e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDO00891.1 - 2.5e-07 30.4 0.0 9.4e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.13 EDO00891.1 - 2.5e-05 23.8 0.0 0.00033 20.2 0.0 2.8 3 1 0 3 3 3 1 Elongation factor G, domain IV PH PF00169.24 EDO00892.1 - 2.7e-29 101.4 0.4 1.4e-14 54.1 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EDO00892.1 - 8.2e-12 45.3 1.6 3.8e-06 27.1 0.1 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EDO00892.1 - 2e-08 34.4 0.3 0.00027 21.0 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EDO00892.1 - 2.4e-06 27.3 0.2 5.9e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EDO00892.1 - 1.6e-05 24.8 0.2 4.7e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Mpv17_PMP22 PF04117.7 EDO00895.1 - 3.1e-12 45.9 1.9 2.2e-10 40.0 0.5 2.3 1 1 1 2 2 2 2 Mpv17 / PMP22 family DUF3325 PF11804.3 EDO00896.1 - 0.045 13.6 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Spore_coat_CotO PF14153.1 EDO00898.1 - 0.0039 16.6 23.6 0.0039 16.6 16.3 2.1 2 0 0 2 2 2 1 Spore coat protein CotO MIP-T3 PF10243.4 EDO00898.1 - 3.8 5.8 52.7 0.094 11.1 29.8 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 EDO00898.1 - 5 5.5 3.8 7 5.1 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0052 PF01933.13 EDO00899.1 - 1.3e-45 156.0 0.0 8.1e-45 153.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Fmp27 PF10344.4 EDO00901.1 - 1.4e-251 837.0 0.0 1.9e-251 836.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 EDO00901.1 - 1.4e-90 304.0 0.1 2.7e-90 303.0 0.1 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EDO00901.1 - 5.5e-56 188.8 0.0 1.3e-55 187.5 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EDO00901.1 - 2.3e-55 186.6 0.6 2.3e-55 186.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EDO00901.1 - 5.6e-37 126.2 0.0 2.9e-36 124.0 0.0 2.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3726 PF12525.3 EDO00901.1 - 0.063 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Apt1 PF10351.4 EDO00902.1 - 1.4e-180 601.0 5.3 1.4e-180 601.0 3.7 2.6 2 1 0 2 2 2 1 Golgi-body localisation protein domain RdRP PF05183.7 EDO00903.1 - 1.6e-135 453.1 0.2 2.8e-135 452.2 0.1 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase Mid2 PF04478.7 EDO00904.1 - 0.00033 20.1 6.1 0.00033 20.1 4.2 3.8 1 1 4 5 5 5 1 Mid2 like cell wall stress sensor ABC2_membrane_4 PF12730.2 EDO00904.1 - 0.018 14.1 0.3 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Utp14 PF04615.8 EDO00904.1 - 2 6.5 9.9 2.5 6.1 6.8 1.1 1 0 0 1 1 1 0 Utp14 protein AvrE PF11725.3 EDO00904.1 - 5.2 3.9 19.7 5.8 3.8 13.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor Senescence_reg PF04520.8 EDO00904.1 - 9.3 6.7 17.5 0.37 11.2 6.5 2.3 1 1 1 2 2 2 0 Senescence regulator Mitofilin PF09731.4 EDO00904.1 - 9.5 4.7 22.6 13 4.3 15.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UBN2 PF14223.1 EDO00905.1 - 0.082 12.6 0.7 0.37 10.5 0.5 2.0 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EDO00905.1 - 0.1 12.6 0.8 0.67 10.0 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 EDO00906.1 - 1.3e-22 80.1 0.0 2.4e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO00906.1 - 3.9e-18 65.6 0.0 8.8e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDO00906.1 - 5.8e-06 25.6 0.4 1.1e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Sporozoite_P67 PF05642.6 EDO00908.1 - 0.061 11.1 1.1 0.082 10.7 0.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GCIP PF13324.1 EDO00908.1 - 0.13 11.4 0.8 0.17 11.0 0.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Dicistro_VP4 PF11492.3 EDO00908.1 - 0.14 12.2 5.3 0.07 13.1 1.1 2.4 2 1 1 3 3 3 0 Cricket paralysis virus, VP4 Alpha-amylase PF00128.19 EDO00909.1 - 1.4e-20 73.9 3.8 4e-20 72.4 0.4 3.1 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EDO00909.1 - 8.6e-14 51.6 0.1 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EDO00909.1 - 2.7e-07 30.1 0.0 4.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDO00909.1 - 1e-06 28.9 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EDO00911.1 - 6.5e-68 229.4 1.4 1e-67 228.8 1.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDO00911.1 - 4.1e-16 58.8 0.1 1.1e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Melibiase PF02065.13 EDO00912.1 - 7.2e-13 47.9 0.0 1.8e-05 23.6 0.0 2.7 1 1 1 2 2 2 2 Melibiase Cellulase PF00150.13 EDO00913.1 - 2.3e-37 128.7 4.3 3.4e-37 128.1 3.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EDO00913.1 - 5.5e-21 74.1 7.9 4e-20 71.4 3.4 2.9 2 0 0 2 2 2 1 Carbohydrate binding domain X2 CBM_1 PF00734.13 EDO00913.1 - 2.1e-11 43.2 14.3 4.8e-11 42.1 9.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_35 PF01301.14 EDO00913.1 - 0.018 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 ABM PF03992.11 EDO00914.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 EDO00914.1 - 0.016 15.6 0.1 0.019 15.3 0.1 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF3829 PF12889.2 EDO00916.1 - 0.038 13.1 0.2 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) RNase_H PF00075.19 EDO00917.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 RNase H ChlI PF13541.1 EDO00917.1 - 0.026 14.0 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase Peptidase_M24 PF00557.19 EDO00918.1 - 7.5e-48 162.8 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDO00918.1 - 1.6e-05 25.4 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Lig_chan PF00060.21 EDO00918.1 - 0.0059 16.3 0.1 0.017 14.8 0.2 1.3 1 1 0 1 1 1 1 Ligand-gated ion channel YjgP_YjgQ PF03739.9 EDO00918.1 - 0.19 10.4 2.7 0.3 9.8 1.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family EutQ PF06249.7 EDO00919.1 - 7.1e-11 41.8 0.0 9.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EDO00919.1 - 2.8e-08 33.0 0.1 4.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EDO00919.1 - 0.00022 20.6 0.1 0.00035 20.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EDO00919.1 - 0.037 13.9 0.2 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 ARD/ARD' family Cupin_6 PF12852.2 EDO00919.1 - 0.055 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin TMEM154 PF15102.1 EDO00920.1 - 0.032 13.9 1.4 0.04 13.6 1.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family Latrophilin PF02354.11 EDO00920.1 - 0.18 10.5 2.6 0.21 10.2 1.8 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region DUF1517 PF07466.6 EDO00921.1 - 0.11 11.4 0.5 0.21 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3381 PF11861.3 EDO00922.1 - 0.48 9.9 9.5 0.79 9.2 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DDE_1 PF03184.14 EDO00923.1 - 3.5e-12 45.9 0.0 6.7e-12 45.0 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO00923.1 - 1.8e-08 34.0 0.1 4.1e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF904 PF06005.7 EDO00924.1 - 0.0019 18.4 1.4 0.0041 17.3 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) zf-CCHC PF00098.18 EDO00924.1 - 0.0085 15.9 1.7 0.016 15.1 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle bZIP_1 PF00170.16 EDO00924.1 - 0.024 14.6 1.5 0.038 13.9 1.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 EDO00924.1 - 0.038 13.7 5.8 3 7.6 0.3 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 EDO00924.1 - 0.044 14.1 1.1 0.061 13.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fungal_trans_2 PF11951.3 EDO00925.1 - 1.7e-57 194.8 1.4 2.3e-57 194.3 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO00925.1 - 2.4e-06 27.3 12.3 4.2e-06 26.5 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF706 PF05153.10 EDO00925.1 - 0.033 13.5 0.1 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF706) HAD_2 PF13419.1 EDO00928.1 - 7.8e-30 104.3 0.0 9.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO00928.1 - 0.042 14.2 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 EDO00929.1 - 3.2e-113 378.6 42.0 4e-113 378.2 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO00929.1 - 5.4e-34 117.4 43.4 7.6e-34 116.9 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.19 EDO00930.1 - 2.3e-56 191.2 0.0 2.7e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO00930.1 - 2.6e-06 27.6 0.3 0.00025 21.1 0.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO00930.1 - 1e-05 24.7 0.7 3.3e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EDO00930.1 - 1.5e-05 24.9 1.1 4.2e-05 23.4 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO00930.1 - 7.7e-05 22.6 0.3 0.00015 21.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO00930.1 - 0.0013 18.4 1.0 0.0061 16.3 0.2 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO00930.1 - 0.0014 18.9 3.8 0.052 13.9 0.6 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO00930.1 - 0.0084 14.9 1.4 0.015 14.1 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDO00930.1 - 0.0091 14.5 0.2 3 6.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Malic_M PF03949.10 EDO00930.1 - 0.03 13.8 0.1 0.94 8.9 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 EDO00930.1 - 0.033 14.2 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EDO00930.1 - 0.034 13.2 0.8 0.063 12.3 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EDO00930.1 - 0.048 12.5 0.3 0.073 11.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Strep_67kDa_ant PF06100.6 EDO00930.1 - 0.1 10.9 0.3 0.16 10.3 0.2 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family zf-UDP PF14569.1 EDO00934.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding RING-finger RTA1 PF04479.8 EDO00935.1 - 6.5e-50 169.7 4.7 1e-49 169.0 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Adeno_GP19K PF04881.8 EDO00935.1 - 0.16 11.7 0.9 3.2 7.4 0.0 2.6 3 0 0 3 3 3 0 Adenovirus GP19K NUDIX PF00293.23 EDO00943.1 - 0.00047 19.8 0.1 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EDO00944.1 - 3.4e-19 68.8 0.0 5.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_18 PF00704.23 EDO00946.1 - 4.5e-06 26.3 0.4 7.8e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AhpC-TSA_2 PF13911.1 EDO00947.1 - 5.9e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EDO00947.1 - 2.5e-06 27.1 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO00947.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin MIP PF00230.15 EDO00948.1 - 6.8e-45 153.2 8.3 1.1e-44 152.6 5.7 1.3 1 0 0 1 1 1 1 Major intrinsic protein Glyco_tranf_2_2 PF10111.4 EDO00949.1 - 0.0066 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDO00949.1 - 0.026 14.2 0.1 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO00949.1 - 0.12 12.1 0.1 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EDO00949.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase DUF1445 PF07286.7 EDO00950.1 - 1.2e-59 200.1 0.0 1.6e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.13 EDO00952.1 - 0.00019 20.3 0.0 0.0004 19.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EDO00953.1 - 8.7e-39 133.2 22.0 1.1e-38 132.8 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDO00953.1 - 0.0021 17.5 4.1 0.0021 17.5 2.8 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2649 PF10854.3 EDO00953.1 - 2.4 8.3 6.7 3.9 7.6 1.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2649) Response_reg PF00072.19 EDO00955.1 - 9.5e-20 70.6 0.0 6.7e-13 48.6 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain MFS_1 PF07690.11 EDO00961.1 - 7.4e-25 87.3 25.7 9.8e-17 60.6 7.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EDO00961.1 - 2e-07 29.5 10.8 0.0002 19.6 1.5 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector DUF4149 PF13664.1 EDO00961.1 - 3 7.9 7.3 6.6 6.8 0.8 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) OATP PF03137.15 EDO00961.1 - 4.3 5.2 15.3 0.42 8.5 1.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 EDO00962.1 - 3.7e-36 124.6 0.0 4.2e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT_3 PF13622.1 EDO00963.1 - 1.1e-40 140.0 0.0 1.6e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily FA_desaturase PF00487.19 EDO00964.1 - 4.6e-13 49.2 5.0 4.6e-13 49.2 3.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EDO00964.1 - 0.0039 17.2 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ndc1_Nup PF09531.5 EDO00965.1 - 8.3 4.6 10.6 3.1 6.1 0.4 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup AMP-binding PF00501.23 EDO00966.1 - 1.1e-28 99.7 0.0 1.4e-27 96.1 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme HTH_Tnp_Tc5 PF03221.11 EDO00967.1 - 0.02 14.7 0.5 0.044 13.6 0.1 1.8 1 1 1 2 2 2 0 Tc5 transposase DNA-binding domain Apo-CIII PF05778.7 EDO00969.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Complex1_LYR PF05347.10 EDO00969.1 - 0.083 12.7 0.7 0.14 11.9 0.5 1.6 1 1 0 1 1 1 0 Complex 1 protein (LYR family) PAP_assoc PF03828.14 EDO00971.1 - 8.9e-20 70.4 0.1 1.9e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDO00971.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zn_clus PF00172.13 EDO00973.1 - 0.11 12.3 7.9 0.23 11.3 5.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_CoxE PF05762.9 EDO00975.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein NUDIX PF00293.23 EDO00976.1 - 1.5e-14 53.7 0.2 2e-14 53.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4449 PF14613.1 EDO00979.1 - 5.4e-07 29.6 2.2 4.9e-06 26.5 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 EDO00979.1 - 0.00074 19.1 0.0 0.0036 16.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function DUF1828 Tricorn_C1 PF14684.1 EDO00979.1 - 0.037 13.8 0.1 0.59 10.0 0.0 2.9 3 0 0 3 3 3 0 Tricorn protease C1 domain Ank_5 PF13857.1 EDO00980.1 - 0.00039 20.5 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO00980.1 - 0.067 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.25 EDO00980.1 - 0.076 12.8 0.1 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 EDO00980.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CBP4 PF07960.6 EDO00980.1 - 9.3 5.8 12.7 6 6.4 0.2 3.1 2 0 0 2 2 2 0 CBP4 Pkinase PF00069.20 EDO00981.1 - 6.9e-55 186.0 0.0 9.9e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO00981.1 - 3.2e-23 82.1 0.0 7.2e-23 80.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO00981.1 - 0.012 14.6 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SH3_9 PF14604.1 EDO00987.1 - 1.9e-14 52.9 0.1 3.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO00987.1 - 2.2e-13 49.3 0.2 3.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EDO00987.1 - 2.2e-12 46.9 2.9 3.1e-12 46.4 2.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EDO00987.1 - 5.6e-11 41.7 0.0 1.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2439 PF10382.4 EDO00989.1 - 5.9e-28 96.8 0.0 1.8e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF1993 PF09351.5 EDO00991.1 - 1.3e-49 168.2 0.0 1.5e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF99 PF01949.11 EDO00991.1 - 0.076 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Orthopox_C10L PF07020.6 EDO00992.1 - 2.8 8.5 10.1 0.43 11.1 2.7 2.0 1 1 1 2 2 2 0 Orthopoxvirus C10L protein Sterol_MT_C PF08498.5 EDO00993.1 - 1.1e-30 105.3 0.1 1.9e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EDO00993.1 - 1.9e-19 69.9 0.0 4.5e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO00993.1 - 5.2e-18 65.0 0.0 7.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO00993.1 - 5.5e-14 52.1 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO00993.1 - 3e-13 49.9 0.0 5.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO00993.1 - 3.2e-12 46.1 0.1 4.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EDO00993.1 - 4.3e-12 46.6 0.0 9.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO00993.1 - 7.3e-12 45.6 0.0 2.4e-11 43.9 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO00993.1 - 4.6e-10 39.0 0.0 8.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EDO00993.1 - 6.9e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO00993.1 - 2.1e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EDO00993.1 - 7.4e-05 22.3 0.1 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EDO00993.1 - 0.00011 21.4 0.0 0.00022 20.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EDO00993.1 - 0.00033 20.2 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EDO00993.1 - 0.00077 18.7 0.6 0.0031 16.7 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase UPF0020 PF01170.13 EDO00993.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EDO00993.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EDO00993.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EDO00993.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Met_10 PF02475.11 EDO00993.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_29 PF03141.11 EDO00993.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_5 PF13893.1 EDO00994.1 - 1.8e-10 40.4 0.0 3.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO00994.1 - 4.6e-09 35.7 0.0 7.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO00994.1 - 6.4e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.10 EDO00995.1 - 1.1e-05 25.1 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDO00995.1 - 0.0002 21.4 0.1 0.00031 20.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like MPLKIP PF15502.1 EDO00996.1 - 0.07 13.8 0.2 0.07 13.8 0.1 2.5 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein DnaJ PF00226.26 EDO00997.1 - 1.1e-18 66.6 1.7 1.1e-18 66.6 1.2 2.9 2 1 0 2 2 2 1 DnaJ domain Dynamin_N PF00350.18 EDO00998.1 - 2.2e-11 43.8 0.3 1.2e-10 41.4 0.0 2.4 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EDO00998.1 - 1.5e-05 24.9 0.0 0.0043 17.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EDO00998.1 - 0.00042 20.6 0.4 0.0038 17.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EDO00998.1 - 0.00084 18.5 0.0 0.0029 16.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ADIP PF11559.3 EDO00998.1 - 0.007 16.2 4.0 0.085 12.7 2.2 2.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding IIGP PF05049.8 EDO00998.1 - 0.0079 15.0 3.2 0.019 13.7 0.0 2.7 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) PspA_IM30 PF04012.7 EDO00998.1 - 0.013 14.8 4.1 0.042 13.2 2.9 1.8 1 0 0 1 1 1 0 PspA/IM30 family TMPIT PF07851.8 EDO00998.1 - 0.013 14.5 0.6 0.033 13.2 0.4 1.6 1 0 0 1 1 1 0 TMPIT-like protein Adeno_IVa2 PF02456.10 EDO00998.1 - 0.02 13.5 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF972 PF06156.8 EDO00998.1 - 0.27 11.6 6.7 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) SseC PF04888.7 EDO00998.1 - 0.32 10.2 2.2 0.78 9.0 1.5 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Med2 PF11214.3 EDO00998.1 - 2.4 8.2 10.9 0.046 13.7 1.2 2.8 2 1 0 2 2 2 0 Mediator complex subunit 2 CHCH PF06747.8 EDO00999.1 - 8.9e-10 38.2 15.8 5.8e-09 35.6 4.1 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EDO00999.1 - 0.00052 19.7 10.9 0.047 13.4 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EDO00999.1 - 0.12 12.4 8.4 0.36 10.9 1.0 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EDO00999.1 - 0.63 10.0 11.4 2.7 8.0 3.3 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Nup54 PF13874.1 EDO01000.1 - 2.8e-47 159.9 0.2 2.8e-47 159.9 0.1 1.9 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EDO01000.1 - 4.2e-07 30.1 70.8 8.6e-07 29.1 30.9 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region Phage_Mu_Gam PF07352.7 EDO01000.1 - 0.024 14.1 0.4 0.07 12.6 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein WIYLD PF10440.4 EDO01000.1 - 0.13 12.1 0.1 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Acetyltransf_3 PF13302.1 EDO01001.1 - 1.9e-19 70.2 0.0 2.7e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO01001.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDO01001.1 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tom5 PF10642.4 EDO01002.1 - 5.7e-25 86.7 0.1 6.1e-25 86.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase GDC-P PF02347.11 EDO01003.1 - 2.1e-179 596.7 0.0 5.5e-166 552.5 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EDO01003.1 - 9.9e-07 28.1 0.1 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDO01003.1 - 0.02 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HpaB_N PF11794.3 EDO01003.1 - 0.17 11.2 0.0 20 4.4 0.0 2.3 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DIOX_N PF14226.1 EDO01004.1 - 2.9e-20 72.9 0.0 5.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDO01004.1 - 1.5e-19 70.1 0.0 2.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 EDO01005.1 - 1.1e-35 123.5 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 EDO01005.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Asparaginase UxaC PF02614.9 EDO01005.1 - 0.29 9.6 0.1 0.42 9.1 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Phosducin PF02114.11 EDO01006.1 - 7.4e-14 51.0 0.0 2.9e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Phosducin WD40 PF00400.27 EDO01008.1 - 4.4e-49 162.6 22.7 9e-10 38.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EDO01008.1 - 5.7e-05 22.9 0.0 0.081 12.6 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.4 EDO01008.1 - 1.3 7.8 4.8 2.1 7.2 3.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WGR PF05406.10 EDO01009.1 - 0.053 13.4 0.2 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 WGR domain A_deaminase PF00962.17 EDO01010.1 - 3.5e-27 95.1 0.0 7.8e-27 94.0 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase TatD_DNase PF01026.16 EDO01010.1 - 0.077 12.1 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase DDE_1 PF03184.14 EDO01013.1 - 1.5e-52 177.8 0.0 2.8e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO01013.1 - 2.3e-09 36.6 0.4 6.1e-08 32.0 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO01013.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO01013.1 - 4.2e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO01013.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle SRP9-21 PF05486.7 EDO01015.1 - 1.6e-29 101.4 0.3 2.3e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EDO01016.1 - 1.4e-120 401.5 3.3 1.7e-120 401.2 2.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.1 EDO01017.1 - 2.9e-33 113.9 0.2 3.9e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 EDO01018.1 - 5.8e-34 115.8 0.5 1.2e-33 114.8 0.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EDO01018.1 - 2.5e-11 43.3 0.0 4.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 EDO01019.1 - 2.1e-18 66.4 0.0 5.6e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDO01019.1 - 2.8e-06 27.2 2.2 7e-05 22.7 0.1 2.9 2 1 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain tRNA_U5-meth_tr PF05958.6 EDO01019.1 - 0.048 12.3 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DnaJ PF00226.26 EDO01020.1 - 9.1e-16 57.3 1.2 2e-15 56.2 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain CytochromB561_N PF09786.4 EDO01020.1 - 0.84 8.0 3.6 0.95 7.8 2.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal RR_TM4-6 PF06459.7 EDO01020.1 - 3.1 7.6 12.4 4.4 7.1 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pneumo_att_G PF05539.6 EDO01020.1 - 3.2 7.0 9.4 4.4 6.5 6.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Menin PF05053.8 EDO01020.1 - 5 5.1 9.0 6.6 4.7 6.3 1.2 1 0 0 1 1 1 0 Menin DUF1308 PF07000.6 EDO01021.1 - 1.9e-88 296.5 0.0 2.6e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF2262 PF10020.4 EDO01021.1 - 0.09 12.9 3.2 7.3 6.7 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) bZIP_1 PF00170.16 EDO01021.1 - 0.51 10.3 4.9 0.27 11.1 1.1 2.2 1 1 1 2 2 2 0 bZIP transcription factor IBR PF01485.16 EDO01023.1 - 7.5 6.5 9.7 26 4.7 6.7 1.9 1 1 0 1 1 1 0 IBR domain FYDLN_acid PF09538.5 EDO01025.1 - 0.078 13.5 8.8 0.24 12.0 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.1 EDO01025.1 - 0.95 9.9 3.8 17 6.0 3.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PAP2 PF01569.16 EDO01026.1 - 2.1 8.0 4.1 4.3 7.0 2.8 1.4 1 0 0 1 1 1 0 PAP2 superfamily AfaD PF05775.7 EDO01027.1 - 0.063 13.2 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MFS_1 PF07690.11 EDO01031.1 - 8.8e-34 116.7 33.5 1.1e-33 116.4 23.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2910 PF11139.3 EDO01032.1 - 0.0078 15.3 1.9 0.012 14.8 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2910) IBR PF01485.16 EDO01034.1 - 0.36 10.7 9.0 2.2 8.2 6.3 2.1 1 1 0 1 1 1 0 IBR domain 2OG-FeII_Oxy_2 PF13532.1 EDO01037.1 - 4.9e-23 81.9 0.0 8.4e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TraL PF07178.6 EDO01041.1 - 0.013 15.4 0.4 0.021 14.8 0.3 1.3 1 0 0 1 1 1 0 TraL protein DUF2985 PF11204.3 EDO01041.1 - 0.043 13.5 0.4 0.065 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) CD34_antigen PF06365.7 EDO01041.1 - 0.059 13.0 0.1 0.068 12.8 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family UDPGT PF00201.13 EDO01043.1 - 1.1e-08 34.1 0.1 1.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Fe-S_assembly PF04384.8 EDO01043.1 - 0.063 13.6 0.1 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Pro-kuma_activ PF09286.6 EDO01044.1 - 7.5e-59 197.8 0.0 1.1e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF3441 PF11923.3 EDO01045.1 - 4e-38 129.4 0.0 4e-38 129.4 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EDO01045.1 - 1.8e-29 102.6 17.8 1.8e-29 102.6 12.3 2.4 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EDO01045.1 - 3.7e-20 71.5 0.0 8.6e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) SR-25 PF10500.4 EDO01047.1 - 0.05 13.0 12.8 0.049 13.1 8.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPT6_acidic PF14632.1 EDO01047.1 - 0.14 12.3 5.0 0.17 12.0 3.4 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF1168 PF06658.7 EDO01047.1 - 0.18 11.2 12.0 0.19 11.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) BLVR PF06375.6 EDO01047.1 - 0.18 11.5 17.7 0.21 11.3 12.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3987 PF13148.1 EDO01047.1 - 0.19 10.2 3.2 0.19 10.2 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Med19 PF10278.4 EDO01047.1 - 0.23 11.1 16.9 0.27 10.9 11.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 EDO01047.1 - 0.63 9.8 9.4 0.7 9.6 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CMS1 PF14617.1 EDO01047.1 - 0.97 8.4 7.4 0.98 8.4 5.2 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NARP1 PF12569.3 EDO01047.1 - 1.1 7.9 6.4 0.99 8.0 4.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SART-1 PF03343.8 EDO01047.1 - 1.2 7.3 13.7 1.2 7.3 9.5 1.0 1 0 0 1 1 1 0 SART-1 family DUF1387 PF07139.6 EDO01047.1 - 4.7 6.7 14.2 5.3 6.5 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Protocadherin PF08374.6 EDO01047.1 - 8.2 5.9 10.0 9 5.8 6.9 1.2 1 0 0 1 1 1 0 Protocadherin RabGAP-TBC PF00566.13 EDO01048.1 - 1.3e-45 155.5 0.0 2.1e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EDO01048.1 - 6.9e-05 22.9 0.3 0.00062 19.8 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EDO01048.1 - 9.9e-05 21.9 1.0 0.0099 15.6 0.2 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 EDO01048.1 - 0.0023 17.0 0.4 0.1 11.9 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 EDO01048.1 - 0.0097 15.2 1.3 0.059 12.7 0.6 2.5 2 0 0 2 2 2 1 EF hand HsbA PF12296.3 EDO01049.1 - 1.5e-37 128.1 6.0 1.5e-37 128.1 4.2 1.7 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 EDO01049.1 - 0.0037 17.0 7.4 0.43 10.3 0.6 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EDO01049.1 - 0.0071 16.5 0.7 0.2 11.9 0.0 3.0 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EDO01049.1 - 0.037 13.2 5.9 0.051 12.7 4.0 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein VirD1 PF07328.6 EDO01049.1 - 0.12 12.2 2.4 3.3 7.5 0.0 2.7 1 1 2 3 3 3 0 T-DNA border endonuclease VirD1 Leu_Phe_trans PF03588.9 EDO01050.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase Ank_2 PF12796.2 EDO01051.1 - 1.8e-17 63.4 0.0 2.1e-09 37.6 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO01051.1 - 3.9e-05 23.2 0.0 0.00033 20.3 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EDO01051.1 - 6.8e-05 22.7 0.0 0.0068 16.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EDO01051.1 - 0.0039 17.6 0.0 0.013 15.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO01051.1 - 0.017 15.3 0.0 0.92 9.8 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Peptidase_C1_2 PF03051.10 EDO01052.1 - 8.3e-154 512.3 0.0 9.7e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EDO01052.1 - 1.2e-07 31.7 1.2 0.013 15.3 0.3 3.1 3 0 0 3 3 3 2 Papain family cysteine protease eIF-5a PF01287.15 EDO01053.1 - 0.00022 21.1 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Abhydrolase_6 PF12697.2 EDO01057.1 - 6.1e-21 75.3 0.1 9.2e-11 42.0 0.1 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO01057.1 - 1e-07 31.8 0.0 2.3e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDO01057.1 - 2.4e-07 30.4 0.0 6.8e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EDO01057.1 - 3.4e-05 23.4 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EDO01057.1 - 0.037 12.8 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EDO01057.1 - 0.045 12.6 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Synuclein PF01387.12 EDO01059.1 - 0.063 13.1 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Synuclein DUF29 PF01724.11 EDO01059.1 - 0.13 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 gag-asp_proteas PF13975.1 EDO01060.1 - 2.5e-09 36.7 0.0 4.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO01060.1 - 7.9e-09 35.9 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EDO01060.1 - 0.00045 20.0 0.2 0.0009 19.0 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.5 EDO01060.1 - 0.0072 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EDO01060.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease LysM PF01476.15 EDO01061.1 - 5e-08 32.7 0.4 0.024 14.5 0.0 4.0 4 0 0 4 4 4 2 LysM domain LRR_6 PF13516.1 EDO01064.1 - 6.1 7.2 11.8 0.13 12.3 0.8 3.9 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_hydro_28 PF00295.12 EDO01066.1 - 9.7e-33 113.4 1.3 1.9e-32 112.5 0.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EDO01066.1 - 0.002 17.8 16.5 0.002 17.8 11.4 2.6 2 1 0 2 2 2 1 Right handed beta helix region Pentapeptide_4 PF13599.1 EDO01066.1 - 0.44 10.3 7.3 0.63 9.8 0.0 3.7 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Na_H_Exchanger PF00999.16 EDO01068.1 - 2.1e-34 118.6 24.0 4.6e-34 117.5 16.6 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family OppC_N PF12911.2 EDO01069.1 - 0.21 11.0 0.9 0.42 10.0 0.3 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF500 PF04366.7 EDO01070.1 - 1.7e-43 147.0 0.0 2.5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF1573 PF07610.6 EDO01071.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) PI-PLC-X PF00388.14 EDO01074.1 - 1.2e-55 186.9 0.1 2e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDO01074.1 - 1.8e-35 121.4 0.0 3.7e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Collagen PF01391.13 EDO01075.1 - 0.00019 20.9 8.5 0.00026 20.4 5.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Cupin_2 PF07883.6 EDO01076.1 - 0.0011 18.4 0.2 0.0013 18.1 0.2 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EDO01076.1 - 0.016 14.8 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain TPR_16 PF13432.1 EDO01077.1 - 0.0017 18.9 4.9 1 10.1 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO01077.1 - 0.34 11.6 2.1 12 6.8 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Isy1 PF06246.7 EDO01078.1 - 1.1e-89 300.2 0.4 1.3e-89 299.9 0.3 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EDO01078.1 - 0.0045 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 YolD-like protein Patatin PF01734.17 EDO01080.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1152 PF06626.7 EDO01080.1 - 0.029 13.5 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Glyco_transf_90 PF05686.7 EDO01081.1 - 8.9e-16 57.5 0.7 1.2e-13 50.5 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L18e PF00828.14 EDO01082.1 - 5.8e-14 52.5 0.1 9.1e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DnaB_2 PF07261.6 EDO01082.1 - 0.16 11.5 0.0 0.58 9.8 0.0 1.8 2 0 0 2 2 2 0 Replication initiation and membrane attachment PX PF00787.19 EDO01084.1 - 4.7e-17 61.7 0.2 1.1e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 EDO01084.1 - 0.51 10.1 3.4 0.52 10.1 0.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit Cullin_binding PF03556.10 EDO01085.1 - 5e-33 113.7 5.0 7.2e-33 113.1 3.4 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EDO01085.1 - 1.7e-09 37.0 0.0 2.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.12 EDO01086.1 - 4.8e-10 39.1 0.0 5.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 WD40 PF00400.27 EDO01087.1 - 6.4e-27 92.4 8.7 1e-10 41.0 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDO01087.1 - 2.9e-18 65.5 0.0 6.8e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex PQQ_3 PF13570.1 EDO01087.1 - 0.014 15.6 0.1 0.75 10.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain IKI3 PF04762.7 EDO01087.1 - 0.047 11.5 0.3 0.068 10.9 0.2 1.3 1 0 0 1 1 1 0 IKI3 family OHCU_decarbox PF09349.5 EDO01089.1 - 1.9e-41 141.9 0.0 2.2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.6 EDO01090.1 - 4.9e-35 119.0 1.3 9.3e-35 118.1 0.9 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EDO01090.1 - 1.8e-14 52.9 0.1 8e-05 22.3 0.0 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 EDO01090.1 - 4.2e-05 23.3 0.0 0.007 16.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 EDO01090.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 EDO01090.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EDO01091.1 - 0.0001 21.9 3.4 0.00028 20.5 2.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDO01091.1 - 0.0031 17.1 0.6 0.0071 16.0 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EDO01091.1 - 0.0034 17.3 1.0 0.0034 17.3 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO01091.1 - 0.0083 15.7 4.7 0.022 14.4 3.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BIR PF00653.16 EDO01091.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-RING_2 PF13639.1 EDO01091.1 - 0.061 13.1 3.3 0.07 12.9 0.7 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 EDO01091.1 - 0.079 12.8 3.2 0.078 12.8 0.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 EDO01091.1 - 0.12 12.2 5.3 0.17 11.8 2.2 2.0 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.1 EDO01091.1 - 0.65 9.6 3.6 2.9 7.5 0.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2 PF00096.21 EDO01093.1 - 2.4e-09 36.9 17.0 0.00011 22.2 2.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO01093.1 - 1.1e-06 28.6 21.8 1.1e-06 28.5 5.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO01093.1 - 0.00015 21.8 16.3 0.052 13.8 3.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO01093.1 - 0.11 12.6 8.1 0.15 12.2 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO01093.1 - 0.19 11.9 7.8 0.24 11.6 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDO01093.1 - 0.87 9.5 10.8 0.53 10.2 1.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDO01093.1 - 8.7 6.1 10.3 0.36 10.5 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Fungal_trans PF04082.13 EDO01094.1 - 7.7e-14 51.1 0.1 1.3e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M57 PF12388.3 EDO01094.1 - 0.036 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Las1 PF04031.8 EDO01096.1 - 8e-53 178.2 0.1 1.2e-52 177.7 0.1 1.2 1 0 0 1 1 1 1 Las1-like VPS28 PF03997.7 EDO01096.1 - 0.063 12.8 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 VPS28 protein Daxx PF03344.10 EDO01097.1 - 0.16 10.4 6.2 0.21 10.0 4.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EDO01097.1 - 0.31 9.7 6.7 0.48 9.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EDO01097.1 - 0.39 10.2 6.7 0.6 9.6 4.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EDO01097.1 - 0.44 8.4 6.0 0.49 8.2 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EDO01097.1 - 2.3 8.4 11.6 4.5 7.5 8.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CobT PF06213.7 EDO01097.1 - 6.3 5.8 9.8 9 5.3 6.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_kinase PF01513.16 EDO01101.1 - 1.9e-69 233.6 0.0 2.8e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Asp PF00026.18 EDO01102.1 - 1.1e-39 136.5 0.1 1.5e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO01102.1 - 3.2e-06 27.2 0.2 1.9e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO01102.1 - 0.014 15.8 0.0 0.75 10.3 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Sugar_tr PF00083.19 EDO01105.1 - 6.5e-106 354.6 24.8 7.8e-106 354.3 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO01105.1 - 4.4e-25 88.1 35.3 1.5e-24 86.3 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EDO01105.1 - 0.0011 17.7 0.5 0.0011 17.7 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) zf-RING_2 PF13639.1 EDO01106.1 - 1.2e-10 40.9 6.8 2.1e-10 40.2 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 EDO01106.1 - 0.00014 21.8 10.3 0.00024 21.0 7.2 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EDO01106.1 - 0.00043 20.1 5.0 0.00088 19.1 3.5 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EDO01106.1 - 0.00055 19.9 5.2 0.0013 18.7 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO01106.1 - 0.0012 18.5 2.3 0.0026 17.5 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO01106.1 - 0.003 17.1 9.8 0.0057 16.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO01106.1 - 0.0061 16.2 7.6 0.011 15.4 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO01106.1 - 0.0072 15.9 5.9 0.013 15.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO01106.1 - 0.0074 16.2 7.5 0.0074 16.2 5.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EDO01106.1 - 0.059 12.9 6.2 0.12 11.9 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 EDO01106.1 - 3.1 7.6 8.6 0.26 11.0 1.6 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S14 PF00253.16 EDO01108.1 - 7.3e-18 63.7 3.9 7.8e-18 63.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EDO01108.1 - 0.013 15.2 0.7 0.017 14.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Apc13p PF05839.6 EDO01109.1 - 6.1e-34 115.8 0.1 6.8e-34 115.7 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 EDO01110.1 - 2.3e-37 127.8 0.0 2.8e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.15 EDO01112.1 - 4.7e-42 143.1 0.0 6.3e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO01112.1 - 3.4e-08 33.4 0.1 8.9e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDO01112.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EDO01113.1 - 4.6e-62 209.8 2.1 6e-62 209.4 1.5 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EDO01113.1 - 9.2e-42 142.6 0.2 1.3e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B IF-2B PF01008.12 EDO01114.1 - 4.7e-76 255.4 0.3 6.7e-76 254.9 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family COMPASS-Shg1 PF05205.7 EDO01116.1 - 3e-26 91.7 0.2 3e-26 91.7 0.1 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 FAA_hydrolase_N PF09298.6 EDO01116.1 - 0.27 11.2 3.4 1.9 8.5 0.0 2.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal ketoacyl-synt PF00109.21 EDO01117.1 - 1.7e-54 184.9 0.0 8.5e-33 113.8 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDO01117.1 - 4.3e-43 147.8 0.0 7.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EDO01117.1 - 9e-35 119.1 0.1 3.2e-34 117.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EDO01117.1 - 5.6e-32 111.0 0.0 8.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EDO01117.1 - 2.9e-22 79.2 0.0 1.2e-21 77.1 0.0 2.1 1 1 1 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EDO01117.1 - 2.6e-16 59.9 0.0 1.3e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 EDO01117.1 - 2.7e-16 59.2 0.0 1e-15 57.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EDO01117.1 - 7.3e-15 55.2 0.3 7.4e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.1 EDO01117.1 - 2.5e-11 43.4 0.0 6.9e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01117.1 - 1.4e-10 41.1 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EDO01117.1 - 2.1e-08 33.9 0.0 4.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDO01117.1 - 6.2e-08 33.5 0.0 2e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EDO01117.1 - 1.2e-07 32.2 0.0 3.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO01117.1 - 8.2e-07 29.4 0.0 2.9e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO01117.1 - 2e-05 23.8 0.0 0.00011 21.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EDO01117.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_24 PF13578.1 EDO01117.1 - 0.015 16.0 0.0 0.05 14.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TMEM61 PF15105.1 EDO01117.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 TMEM61 protein family MFS_1 PF07690.11 EDO01118.1 - 4.4e-31 107.8 37.9 6.4e-31 107.3 26.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO01118.1 - 5.9e-10 38.3 15.8 5.9e-10 38.3 11.0 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDO01118.1 - 7.8e-09 34.2 14.6 1.3e-08 33.5 10.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EDO01118.1 - 0.0056 16.6 0.8 0.0056 16.6 0.5 3.2 2 1 0 3 3 3 1 Poxvirus virion envelope protein A14 Pyr_redox_3 PF13738.1 EDO01119.1 - 1.2e-15 58.1 0.1 7.5e-09 35.9 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO01119.1 - 5.3e-07 28.8 0.0 7.5e-05 21.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDO01119.1 - 1.7e-06 27.9 0.0 4.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EDO01119.1 - 5.5e-06 24.8 0.0 3e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 EDO01119.1 - 0.035 13.2 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EDO01119.1 - 0.044 13.6 0.0 1.3 8.8 0.0 2.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO01119.1 - 0.071 12.8 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.17 EDO01120.1 - 3.3e-55 187.4 0.0 4.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EDO01123.1 - 6.9e-28 97.6 0.0 5.6e-27 94.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Y_phosphatase PF00102.22 EDO01124.1 - 3.3e-59 200.0 0.0 1.2e-29 103.3 0.0 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EDO01124.1 - 0.0051 16.8 0.3 0.021 14.9 0.2 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EDO01124.1 - 0.007 16.6 0.1 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EDO01124.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Uds1 PF15456.1 EDO01124.1 - 0.0086 16.0 0.4 0.023 14.6 0.2 1.7 1 0 0 1 1 1 1 Up-regulated During Septation UCH PF00443.24 EDO01125.1 - 2.3e-37 128.5 0.0 3.5e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO01125.1 - 5.2e-07 29.3 0.0 4.3e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 EDO01126.1 - 8.7e-24 84.2 14.8 1.5e-23 83.5 10.3 1.4 1 0 0 1 1 1 1 Alb1 DDE_Tnp_1_2 PF13586.1 EDO01126.1 - 0.12 12.5 0.7 0.22 11.7 0.5 1.5 1 0 0 1 1 1 0 Transposase DDE domain Ribosomal_S8e PF01201.17 EDO01126.1 - 0.78 9.8 6.4 1.3 9.2 4.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e CAF-1_p150 PF11600.3 EDO01126.1 - 1.5 8.1 19.6 1.9 7.8 13.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hex_IIIa PF02455.11 EDO01126.1 - 3.2 6.3 9.5 3.7 6.1 6.6 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Prp19_bind PF06991.6 EDO01127.1 - 1.1e-45 156.0 38.5 1.1e-45 156.0 26.7 1.6 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF3295 PF11702.3 EDO01127.1 - 0.0022 17.0 11.0 0.0022 17.0 7.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) MFMR PF07777.6 EDO01127.1 - 6.3 6.6 8.9 12 5.7 5.1 2.1 2 0 0 2 2 2 0 G-box binding protein MFMR Alpha-L-AF_C PF06964.7 EDO01128.1 - 2.9e-37 128.1 0.0 4.7e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EDO01128.1 - 0.011 15.7 1.5 0.035 14.0 1.0 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain PQ-loop PF04193.9 EDO01131.1 - 5.6e-26 89.8 9.3 3.3e-20 71.4 0.0 3.6 3 0 0 3 3 3 2 PQ loop repeat DUF1301 PF06979.7 EDO01131.1 - 0.087 12.9 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) RhodobacterPufX PF11511.3 EDO01131.1 - 0.12 11.7 4.5 0.065 12.6 0.7 2.3 2 1 0 2 2 2 0 Intrinsic membrane protein PufX Glyco_hydro_17 PF00332.13 EDO01132.1 - 1.4e-28 99.8 0.3 1.1e-27 96.9 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Upf2 PF04050.9 EDO01133.1 - 0.018 14.7 0.1 0.021 14.5 0.1 1.0 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF3592 PF12158.3 EDO01133.1 - 0.022 14.5 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) GTP_EFTU_D3 PF03143.12 EDO01133.1 - 0.097 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain Lipase_GDSL PF00657.17 EDO01136.1 - 7.2e-15 55.4 1.0 8.9e-15 55.1 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CFEM PF05730.6 EDO01137.1 - 7.4e-08 32.1 12.6 1.3e-07 31.2 8.8 1.4 1 0 0 1 1 1 1 CFEM domain FXa_inhibition PF14670.1 EDO01137.1 - 0.96 9.6 6.3 1.9 8.6 4.4 1.6 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site TIL PF01826.12 EDO01137.1 - 2.6 8.2 10.4 4.1 7.6 7.2 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Chlam_OMP6 PF03504.8 EDO01138.1 - 0.074 13.3 0.3 0.084 13.1 0.2 1.0 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 FAD_binding_4 PF01565.18 EDO01142.1 - 1.6e-16 60.0 0.0 2.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3735 PF12537.3 EDO01143.1 - 0.1 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Glyco_hydro_11 PF00457.12 EDO01144.1 - 1e-78 262.8 23.5 1.3e-78 262.5 16.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EDO01144.1 - 9.4e-09 34.7 12.5 9.4e-09 34.7 8.7 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain V-SNARE_C PF12352.3 EDO01146.1 - 1.8e-15 56.7 0.2 3.9e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EDO01146.1 - 0.00038 20.0 0.2 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.6 EDO01146.1 - 0.0083 15.5 0.5 0.011 15.1 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator Sigma70_r4 PF04545.11 EDO01146.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Pkinase PF00069.20 EDO01148.1 - 3e-21 75.7 0.0 4.3e-16 58.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01148.1 - 1.6e-06 27.3 0.0 7.2e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4194 PF13835.1 EDO01148.1 - 0.092 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) adh_short PF00106.20 EDO01150.1 - 8.5e-10 38.7 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO01150.1 - 0.0026 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDO01150.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EDO01150.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DHquinase_II PF01220.14 EDO01150.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Dehydroquinase class II DUF3918 PF13056.1 EDO01150.1 - 0.063 12.5 0.1 0.94 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) KR PF08659.5 EDO01150.1 - 0.07 12.7 0.0 0.27 10.8 0.0 2.0 2 1 0 2 2 2 0 KR domain DUF4139 PF13598.1 EDO01151.1 - 8.9e-53 179.6 10.7 7.7e-39 133.8 0.0 3.9 3 1 0 4 4 4 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EDO01151.1 - 1.5e-11 44.6 0.8 1.5e-11 44.6 0.6 4.3 2 1 2 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EDO01151.1 - 5.5e-07 29.8 36.1 1.4e-05 25.2 25.0 2.4 1 1 0 1 1 1 1 Nucleoporin FG repeat region B_lectin PF01453.19 EDO01152.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 D-mannose binding lectin Asp PF00026.18 EDO01155.1 - 1.7e-65 221.3 11.6 2.1e-65 221.0 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO01155.1 - 0.00042 20.3 0.1 0.0053 16.7 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO01155.1 - 0.00084 19.8 4.7 0.011 16.2 0.4 3.2 3 1 0 3 3 3 1 Aspartyl protease MSP1_C PF07462.6 EDO01155.1 - 0.013 13.9 0.7 0.018 13.4 0.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GATase PF00117.23 EDO01156.1 - 2.2e-38 131.6 0.0 4.5e-38 130.6 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EDO01156.1 - 2.8e-32 110.2 0.0 6.4e-32 109.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EDO01156.1 - 7.9e-11 41.3 0.0 6e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EDO01156.1 - 3.9e-08 33.0 0.0 7.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EDO01156.1 - 0.0014 17.2 0.0 0.0055 15.3 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EDO01156.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 EDO01156.1 - 0.0028 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 EDO01156.1 - 0.0042 16.4 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EDO01156.1 - 0.018 14.0 0.1 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 EDO01156.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EDO01156.1 - 0.036 13.5 0.1 0.083 12.3 0.0 1.8 1 1 0 1 1 1 0 PP-loop family DUF3220 PF11516.3 EDO01156.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) TPK_catalytic PF04263.11 EDO01157.1 - 5.2e-23 80.9 0.0 1.2e-21 76.5 0.0 2.3 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EDO01157.1 - 6.9e-21 73.7 0.1 1.1e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Galactosyl_T PF01762.16 EDO01157.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase CHCH PF06747.8 EDO01158.1 - 1.7e-06 27.7 3.5 3.1e-06 26.9 2.4 1.4 1 0 0 1 1 1 1 CHCH domain MRP_L53 PF10780.4 EDO01158.1 - 1.2 9.2 3.5 0.36 10.8 0.2 1.8 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 GCK PF07802.6 EDO01158.1 - 6.3 7.0 9.7 0.18 11.9 2.1 1.8 2 0 0 2 2 2 0 GCK domain DUF892 PF05974.7 EDO01159.1 - 0.016 15.0 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Secretogranin_V PF05281.6 EDO01159.1 - 0.018 14.3 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) ETRAMP PF09716.5 EDO01159.1 - 0.25 11.2 2.8 0.59 10.1 1.9 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4337 PF14235.1 EDO01159.1 - 8.9 6.1 7.6 16 5.2 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) BTB PF00651.26 EDO01160.1 - 3.1e-12 46.4 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ndc80_HEC PF03801.8 EDO01160.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Phage_integ_N PF09003.5 EDO01166.1 - 0.24 11.1 2.8 2 8.2 0.5 2.3 1 1 1 2 2 2 0 Bacteriophage lambda integrase, N-terminal domain FMO-like PF00743.14 EDO01168.1 - 6.8e-19 67.4 0.1 2.4e-18 65.6 0.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDO01168.1 - 5.2e-18 65.8 0.1 1.7e-17 64.2 0.1 1.9 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO01168.1 - 2.2e-11 43.3 0.7 4.4e-10 38.9 0.2 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDO01168.1 - 4.2e-11 43.1 0.0 2.8e-09 37.1 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO01168.1 - 1.1e-06 27.9 0.0 0.00031 19.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDO01168.1 - 8.8e-06 25.6 0.0 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EDO01168.1 - 6.5e-05 22.1 0.3 0.0098 15.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EDO01168.1 - 0.00011 22.5 0.3 0.48 10.8 0.0 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EDO01168.1 - 0.00042 20.0 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDO01168.1 - 0.0014 18.7 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EDO01168.1 - 0.002 17.5 0.1 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EDO01168.1 - 0.014 14.8 0.0 0.82 9.0 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EDO01168.1 - 0.032 14.0 0.8 1.1 9.1 0.1 2.9 3 1 0 3 3 3 0 ThiF family TrkA_N PF02254.13 EDO01168.1 - 0.036 14.0 0.3 6.4 6.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EDO01168.1 - 0.08 12.6 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EDO01168.1 - 0.093 11.6 0.0 3.1 6.6 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDO01168.1 - 0.14 11.0 0.0 2.1 7.1 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein F420_oxidored PF03807.12 EDO01168.1 - 0.14 12.6 0.0 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HAD PF12710.2 EDO01171.1 - 1.5e-16 61.1 0.0 1.9e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDO01171.1 - 1.8e-07 30.5 0.1 1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EDO01171.1 - 2.3e-05 24.6 0.0 8.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EDO01171.1 - 0.00011 21.6 0.0 0.00035 19.9 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EDO01171.1 - 0.017 15.5 0.5 1.4 9.2 0.0 2.6 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase She9_MDM33 PF05546.6 EDO01172.1 - 5.6e-91 303.7 4.1 8.4e-91 303.1 2.8 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EDO01172.1 - 0.019 14.5 0.9 0.039 13.5 0.6 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_35 PF01301.14 EDO01173.1 - 2.6e-83 280.0 0.0 4.3e-83 279.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EDO01173.1 - 3.7e-67 225.2 8.8 6.8e-67 224.3 6.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EDO01173.1 - 1.5e-49 166.8 10.9 6.7e-25 87.5 2.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EDO01173.1 - 1.1e-22 79.1 0.1 2.6e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 fn3 PF00041.16 EDO01173.1 - 0.014 15.4 3.4 0.075 13.1 0.0 3.3 3 0 0 3 3 3 0 Fibronectin type III domain DUF2890 PF11081.3 EDO01174.1 - 0.31 11.0 1.4 0.39 10.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosom_S12_S23 PF00164.20 EDO01175.1 - 1.4e-38 131.0 1.4 1.9e-38 130.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 EDO01176.1 - 2.8e-141 470.2 9.0 3.4e-141 469.9 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 EDO01176.1 - 0.034 13.9 0.9 0.11 12.3 0.6 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor HNH_3 PF13392.1 EDO01176.1 - 0.57 9.6 2.5 0.5 9.8 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease PAT1 PF09770.4 EDO01177.1 - 6.7e-246 818.4 22.0 8.3e-246 818.1 15.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3533 PF12051.3 EDO01178.1 - 5.9e-109 364.3 19.3 7e-109 364.0 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DndB PF14072.1 EDO01178.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated Form_Nir_trans PF01226.12 EDO01180.1 - 1.6e-80 269.6 18.5 1.8e-80 269.4 12.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF1524 PF07510.6 EDO01182.1 - 1.2e-12 47.8 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EDO01182.1 - 0.12 11.9 0.3 0.5 10.0 0.2 2.0 1 1 0 1 1 1 0 HNH endonuclease ADH_N PF08240.7 EDO01183.1 - 1.6e-28 98.6 1.1 1.6e-28 98.6 0.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EDO01183.1 - 9.6e-08 31.5 0.8 1.7e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EDO01183.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein NMD3 PF04981.8 EDO01184.1 - 1e-75 253.9 2.7 1e-75 253.9 1.9 1.4 2 0 0 2 2 2 1 NMD3 family DUF35_N PF12172.3 EDO01184.1 - 0.0082 16.0 0.5 1.1 9.2 0.2 2.6 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 EDO01184.1 - 1 9.2 10.3 9.9 6.0 3.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon TauD PF02668.11 EDO01185.1 - 2.5e-38 132.2 0.3 3.1e-38 131.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3662 PF12401.3 EDO01186.1 - 0.048 13.8 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Pkinase PF00069.20 EDO01187.1 - 7.1e-25 87.6 0.0 8.8e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01187.1 - 6.2e-15 54.9 0.0 2.7e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO01187.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.8 EDO01187.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) PBP1_TM PF14812.1 EDO01187.1 - 0.38 11.1 4.2 1.1 9.6 2.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 EDO01187.1 - 0.61 8.4 7.1 0.97 7.8 4.9 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EDO01187.1 - 4.1 6.5 7.0 6.8 5.8 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein LCE PF14672.1 EDO01189.1 - 0.048 14.1 1.3 0.051 14.0 0.9 1.1 1 0 0 1 1 1 0 Late cornified envelope MFS_1 PF07690.11 EDO01199.1 - 7.1e-31 107.2 37.2 2.1e-29 102.3 15.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDO01199.1 - 3.4e-05 23.5 7.8 0.041 13.6 0.1 2.7 2 0 0 2 2 2 2 MFS_1 like family Atrophin-1 PF03154.10 EDO01199.1 - 1.7 6.6 8.8 2.5 6.1 6.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Vfa1 PF08432.5 EDO01199.1 - 1.9 8.4 10.5 3.1 7.7 7.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rad60-SLD_2 PF13881.1 EDO01201.1 - 1.1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDO01201.1 - 1.9e-05 23.9 0.0 4.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EDO01201.1 - 0.0013 18.9 0.2 0.0033 17.5 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EDO01202.1 - 6.2e-21 74.7 0.0 8e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 EDO01203.1 - 3.9e-29 101.6 0.1 2.2e-14 53.9 0.5 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO01203.1 - 1.1e-12 48.5 10.4 8e-05 22.7 1.4 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO01203.1 - 1.1e-06 29.4 0.0 0.052 14.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDO01203.1 - 2e-06 27.6 0.1 0.0033 17.3 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDO01203.1 - 3.7e-06 26.3 0.1 0.078 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO01203.1 - 1.4e-05 25.5 1.2 0.0045 17.3 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EDO01203.1 - 0.00017 21.6 0.0 0.073 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO01203.1 - 0.00033 20.8 0.2 0.49 10.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EDO01203.1 - 0.00042 20.2 0.0 1.5 8.7 0.0 3.3 4 1 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EDO01203.1 - 0.00063 19.2 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 EDO01203.1 - 0.00082 19.8 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EDO01203.1 - 0.0022 17.0 0.0 3.7 6.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.12 EDO01203.1 - 0.0023 17.8 0.1 6.6 6.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EDO01203.1 - 0.0025 17.3 0.1 0.63 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EDO01203.1 - 0.0035 17.6 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO01203.1 - 0.004 17.0 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDO01203.1 - 0.0042 16.5 0.1 1.7 8.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EDO01203.1 - 0.0075 15.9 0.0 0.78 9.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EDO01203.1 - 0.01 15.5 0.0 4.3 7.0 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EDO01203.1 - 0.021 14.2 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EDO01203.1 - 0.022 14.2 0.2 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EDO01203.1 - 0.022 14.4 0.0 0.99 9.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EDO01203.1 - 0.022 14.7 0.5 11 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.1 EDO01203.1 - 0.047 13.2 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EDO01203.1 - 0.066 12.3 0.0 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EDO01203.1 - 0.1 11.0 0.1 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDO01203.1 - 0.12 11.2 0.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EDO01203.1 - 0.14 12.0 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.5 EDO01203.1 - 0.16 11.1 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.7 EDO01203.1 - 0.16 11.1 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DUF3584 PF12128.3 EDO01203.1 - 0.18 9.1 0.1 0.8 6.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SIR2 PF02146.12 EDO01206.1 - 3.1e-27 95.4 0.0 8.3e-09 35.4 0.0 3.6 3 0 0 3 3 3 3 Sir2 family Zn_clus PF00172.13 EDO01206.1 - 0.00013 21.8 17.1 0.00013 21.8 11.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1013 PF06242.6 EDO01206.1 - 0.055 13.4 5.0 0.48 10.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) P5CR_dimer PF14748.1 EDO01207.1 - 7.4e-26 90.2 0.1 3.1e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDO01207.1 - 5.9e-15 55.4 0.2 1.4e-14 54.2 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EDO01207.1 - 0.091 12.2 2.5 0.5 9.8 1.1 3.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pro_dh PF01619.13 EDO01208.1 - 2.4e-34 118.7 0.8 6.7e-34 117.2 0.5 1.6 1 1 0 1 1 1 1 Proline dehydrogenase Aminotran_5 PF00266.14 EDO01210.1 - 1e-18 67.2 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Kelch_5 PF13854.1 EDO01211.1 - 1.1e-09 37.9 0.3 1.1e-09 37.9 0.2 3.8 5 0 0 5 5 5 1 Kelch motif SKG6 PF08693.5 EDO01211.1 - 0.0035 16.6 0.2 0.0066 15.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2681 PF10883.3 EDO01211.1 - 0.038 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Herpes_gE PF02480.11 EDO01211.1 - 0.15 10.2 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sarcoglycan_2 PF05510.8 EDO01211.1 - 0.16 10.2 0.0 8.4 4.5 0.0 2.1 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Methyltransf_11 PF08241.7 EDO01212.1 - 7e-17 61.7 0.1 1.3e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01212.1 - 7.1e-15 55.0 0.1 1e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO01212.1 - 6.2e-14 51.8 0.0 8.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO01212.1 - 1.8e-11 44.2 0.4 5.2e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO01212.1 - 2.2e-11 44.2 0.0 3.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO01212.1 - 3e-11 42.9 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EDO01212.1 - 1.5e-10 41.1 0.0 2.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO01212.1 - 4e-09 36.8 0.1 8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO01212.1 - 4.8e-09 35.6 0.0 1.2e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDO01212.1 - 9.8e-08 31.5 0.1 1.5e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EDO01212.1 - 2.2e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EDO01212.1 - 7.2e-05 22.4 0.2 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EDO01212.1 - 0.00038 19.6 0.1 0.00069 18.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EDO01212.1 - 0.00056 19.1 0.0 0.00085 18.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB GCD14 PF08704.5 EDO01212.1 - 0.0014 18.2 0.2 0.0031 17.0 0.1 1.6 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit UPF0020 PF01170.13 EDO01212.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 EDO01212.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 EDO01212.1 - 0.0052 16.4 0.1 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EDO01212.1 - 0.0069 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EDO01212.1 - 0.015 14.0 0.1 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ADH_zinc_N PF00107.21 EDO01212.1 - 0.019 14.5 0.2 0.068 12.7 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.15 EDO01212.1 - 0.047 12.7 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 EDO01212.1 - 0.058 12.6 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase zf-C2HC5 PF06221.8 EDO01214.1 - 2.6e-22 78.3 5.7 4.2e-22 77.6 4.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TPR_11 PF13414.1 EDO01215.1 - 1e-10 41.0 3.1 7.6e-07 28.6 0.0 4.8 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EDO01215.1 - 2.5e-08 33.1 0.4 0.0013 18.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO01215.1 - 2.5e-06 27.9 0.0 1.4e-05 25.5 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO01215.1 - 0.00038 20.0 0.1 0.08 12.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO01215.1 - 0.0011 18.5 0.0 2.2 8.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO01215.1 - 0.0048 16.5 0.9 1.9 8.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO01215.1 - 0.024 14.5 7.7 0.77 9.7 0.2 4.1 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO01215.1 - 0.052 13.8 0.2 5.6 7.3 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO01215.1 - 0.06 13.9 6.0 1.3 9.9 0.1 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO01215.1 - 0.072 13.3 0.1 9.7 6.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GYF PF02213.11 EDO01216.1 - 6e-16 57.7 0.2 1.7e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 GYF domain DNA_pol_lambd_f PF10391.4 EDO01217.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF2076 PF09849.4 EDO01218.1 - 0.0053 16.8 1.8 0.0066 16.5 1.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_OmpA PF13436.1 EDO01218.1 - 0.027 14.1 0.7 0.042 13.4 0.5 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Zip PF02535.17 EDO01218.1 - 0.057 12.4 10.9 0.074 12.0 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Gly-zipper_Omp PF13488.1 EDO01218.1 - 0.079 12.6 5.7 0.15 11.7 4.0 1.4 1 0 0 1 1 1 0 Glycine zipper AMP-binding PF00501.23 EDO01219.1 - 1.1e-240 798.1 0.0 1.3e-91 307.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EDO01219.1 - 2.3e-164 545.4 0.0 1.1e-36 126.2 0.0 8.7 6 3 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EDO01219.1 - 2.5e-44 149.3 7.6 1.5e-09 37.9 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDO01219.1 - 2.5e-21 76.4 0.0 2.2e-06 28.5 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 EDO01219.1 - 0.00046 18.8 6.7 0.27 9.7 0.1 5.8 4 2 0 5 5 5 2 Alcohol acetyltransferase HxxPF_rpt PF13745.1 EDO01219.1 - 0.012 15.9 1.2 0.78 10.0 0.3 4.2 5 0 0 5 5 5 0 HxxPF-repeated domain WES_acyltransf PF03007.11 EDO01219.1 - 0.059 12.9 1.3 25 4.2 0.0 4.5 5 0 0 5 5 5 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Fungal_lectin PF07938.7 EDO01221.1 - 0.097 11.9 0.2 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Fungal fucose-specific lectin K_oxygenase PF13434.1 EDO01222.1 - 5.3e-111 370.8 0.0 6.3e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDO01222.1 - 2.8e-08 34.0 0.0 7.1e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO01222.1 - 5.2e-07 29.5 0.0 2.5e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDO01222.1 - 2.8e-05 24.0 0.0 0.00067 19.5 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrwC PF08751.6 EDO01224.1 - 0.021 14.2 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 TrwC relaxase Alba PF01918.16 EDO01225.1 - 8.2e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Alba Peptidase_S64 PF08192.6 EDO01225.1 - 0.41 8.9 4.4 0.46 8.7 3.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF202 PF02656.10 EDO01226.1 - 1.1e-14 54.4 2.6 1.5e-14 53.9 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Tctex-1 PF03645.8 EDO01227.1 - 3.2e-36 123.2 0.0 3.7e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.2 EDO01229.1 - 1.7e-05 24.4 0.1 3.8e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO01229.1 - 6.7e-05 22.4 0.1 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Herpes_BLRF2 PF05812.7 EDO01231.1 - 4.8e-05 23.1 5.7 7e-05 22.6 3.9 1.2 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Ion_trans PF00520.26 EDO01231.1 - 0.00013 21.2 2.3 0.0028 16.9 2.2 2.0 2 0 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.16 EDO01231.1 - 0.0058 16.5 4.1 0.0092 15.9 2.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor Frigida PF07899.6 EDO01231.1 - 0.036 12.8 0.1 0.085 11.5 0.2 1.5 2 0 0 2 2 2 0 Frigida-like protein DUF1192 PF06698.6 EDO01231.1 - 0.042 13.6 1.5 0.074 12.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) YebO PF13974.1 EDO01231.1 - 0.047 13.4 0.3 0.083 12.6 0.2 1.4 1 0 0 1 1 1 0 YebO-like protein Sugarporin_N PF11471.3 EDO01231.1 - 0.17 11.5 1.8 0.37 10.4 1.3 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DivIC PF04977.10 EDO01231.1 - 0.75 9.3 3.9 1.3 8.5 2.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Fmp27_WPPW PF10359.4 EDO01231.1 - 3.2 6.0 6.5 0.5 8.7 2.0 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain RRM_1 PF00076.17 EDO01232.1 - 3.4e-16 58.6 0.0 5.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO01232.1 - 2.6e-15 56.1 0.0 4.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO01232.1 - 4.7e-05 23.1 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EDO01232.1 - 0.0026 17.3 1.5 0.0032 17.0 1.0 1.1 1 0 0 1 1 1 1 IncA protein CASP_C PF08172.7 EDO01232.1 - 0.014 14.4 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal DUF904 PF06005.7 EDO01232.1 - 0.038 14.2 3.9 0.067 13.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Packaging_FI PF14000.1 EDO01232.1 - 0.041 14.0 1.9 0.06 13.5 1.2 1.5 1 1 0 1 1 1 0 DNA packaging protein FI V_ATPase_I PF01496.14 EDO01232.1 - 0.054 11.3 0.2 0.058 11.2 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EDO01232.1 - 0.09 13.1 0.5 0.12 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EDO01232.1 - 0.091 11.7 0.8 0.1 11.6 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EDO01232.1 - 0.11 12.0 2.9 0.15 11.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.19 EDO01232.1 - 0.16 11.6 1.5 0.22 11.2 1.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GAS PF13851.1 EDO01232.1 - 0.17 11.0 3.5 0.23 10.6 2.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EDO01232.1 - 0.29 10.6 4.6 0.41 10.1 3.2 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4446 PF14584.1 EDO01232.1 - 0.37 10.6 2.4 0.58 9.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HECT PF00632.20 EDO01234.1 - 7.4e-91 304.5 0.0 1.1e-90 304.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EDO01234.1 - 3.8e-32 109.7 17.6 1.2e-10 41.0 0.2 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EDO01234.1 - 1.1e-15 57.2 0.0 3.9e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 C2 domain CFEM PF05730.6 EDO01235.1 - 1.3 8.9 11.2 3.3 7.5 7.3 2.0 1 1 1 2 2 2 0 CFEM domain Fe-ADH PF00465.14 EDO01238.1 - 1.5e-71 240.9 0.0 1.9e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EDO01238.1 - 7.1e-07 28.7 0.0 2.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Pkinase PF00069.20 EDO01239.1 - 1.1e-63 214.7 0.0 2.3e-63 213.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01239.1 - 5.7e-42 143.5 0.0 9.9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO01239.1 - 0.0007 18.6 0.0 0.0018 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Arm PF00514.18 EDO01239.1 - 0.051 13.4 0.1 32 4.5 0.0 4.7 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Surf_Ag_VNR PF07244.10 EDO01240.1 - 2 8.8 4.8 3.3 8.2 0.3 2.9 2 1 1 3 3 3 0 Surface antigen variable number repeat Mur_ligase_M PF08245.7 EDO01241.1 - 8.8e-06 25.8 0.0 2e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain PRK PF00485.13 EDO01242.1 - 3.2e-07 30.0 0.0 4.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EDO01242.1 - 1.2e-06 29.3 1.1 2.2e-05 25.2 0.7 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EDO01242.1 - 0.00039 19.4 0.1 0.032 13.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EDO01242.1 - 0.00041 20.6 0.1 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDO01242.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EDO01242.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EDO01242.1 - 0.0026 17.6 0.2 0.0067 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO01242.1 - 0.0035 17.4 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO01242.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KTI12 PF08433.5 EDO01242.1 - 0.0089 15.2 0.1 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF2075 PF09848.4 EDO01242.1 - 0.0098 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EDO01242.1 - 0.017 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.12 EDO01242.1 - 0.019 14.3 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 EDO01242.1 - 0.019 14.0 0.2 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EDO01242.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EDO01242.1 - 0.026 13.6 0.2 0.2 10.7 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 EDO01242.1 - 0.03 13.7 0.5 0.049 13.0 0.1 1.5 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EDO01242.1 - 0.04 13.3 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EDO01242.1 - 0.04 13.6 0.1 0.085 12.5 0.1 1.5 2 0 0 2 2 1 0 NTPase ABC_tran PF00005.22 EDO01242.1 - 0.044 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EDO01242.1 - 0.052 13.0 0.1 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 EDO01242.1 - 0.058 12.9 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EDO01242.1 - 0.085 12.7 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ADK PF00406.17 EDO01242.1 - 0.087 12.7 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.1 EDO01242.1 - 0.087 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDO01242.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EDO01242.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EDO01242.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PRELI PF04707.9 EDO01244.1 - 2.4e-43 147.4 0.7 2.8e-43 147.2 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.16 EDO01245.1 - 8e-24 83.6 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO01245.1 - 4.4e-15 55.5 0.0 7.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EDO01245.1 - 0.058 13.3 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ycf1 PF05758.7 EDO01245.1 - 6 4.4 7.7 7.9 4.0 5.4 1.1 1 0 0 1 1 1 0 Ycf1 HTH_Tnp_Tc5 PF03221.11 EDO01246.1 - 1.7e-06 27.7 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Chromo PF00385.19 EDO01249.1 - 3.3e-13 49.0 0.8 7.8e-13 47.8 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDO01249.1 - 2.4e-12 46.9 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDO01250.1 - 3.6e-18 65.7 0.0 1.1e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDO01250.1 - 6.9e-07 28.9 2.6 1.5e-06 27.8 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle APO_RNA-bind PF05634.6 EDO01250.1 - 0.031 13.4 0.5 0.068 12.3 0.3 1.5 1 0 0 1 1 1 0 APO RNA-binding zf-CCHC_5 PF14787.1 EDO01250.1 - 1.8 8.1 13.3 0.035 13.6 3.8 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Sipho_tail PF05709.6 EDO01251.1 - 0.075 12.1 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein DUF2413 PF10310.4 EDO01252.1 - 1.3e-05 24.2 0.1 1.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flagellin_N PF00669.15 EDO01252.1 - 0.016 15.0 1.3 0.12 12.1 0.1 2.6 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Laminin_II PF06009.7 EDO01252.1 - 0.035 13.8 0.4 0.083 12.6 0.1 1.6 2 0 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 EDO01252.1 - 0.045 12.9 1.3 0.1 11.7 0.8 1.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EDO01252.1 - 0.051 13.3 1.4 0.17 11.6 0.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EDO01252.1 - 0.1 12.5 2.6 1.2 9.0 0.9 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 EDO01252.1 - 0.45 10.8 2.9 3.7 7.8 1.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SHMT PF00464.14 EDO01255.1 - 2.3e-194 645.3 0.0 2.7e-194 645.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EDO01255.1 - 9.7e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDO01255.1 - 0.059 12.0 0.0 0.093 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_L19e PF01280.15 EDO01256.1 - 3.4e-61 205.3 7.4 3.4e-61 205.3 5.1 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EDO01256.1 - 0.02 14.1 2.0 0.02 14.1 1.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3554 PF12074.3 EDO01257.1 - 4.1e-94 315.8 14.5 6e-94 315.2 2.1 4.3 4 1 0 4 4 4 2 Domain of unknown function (DUF3554) HEAT PF02985.17 EDO01257.1 - 4e-37 122.9 27.5 0.021 14.8 0.0 19.4 20 0 0 20 20 19 10 HEAT repeat HEAT_2 PF13646.1 EDO01257.1 - 6.2e-35 119.3 45.4 4.2e-10 39.7 0.0 15.4 8 4 10 19 19 18 9 HEAT repeats HEAT_EZ PF13513.1 EDO01257.1 - 1.8e-31 107.8 51.5 5.4e-06 26.7 0.0 22.2 16 6 10 26 26 26 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO01257.1 - 3.3e-16 59.4 0.1 0.46 10.8 0.0 9.9 7 3 2 10 10 10 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EDO01257.1 - 2e-11 44.0 2.8 0.039 13.7 0.0 9.0 8 1 1 10 10 10 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EDO01257.1 - 2.6e-08 33.9 1.4 0.022 14.6 0.0 5.5 5 0 0 5 5 5 2 Parkin co-regulated protein Ipi1_N PF12333.3 EDO01257.1 - 0.00014 21.7 0.1 0.53 10.2 0.0 5.5 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation FANCI_S2 PF14676.1 EDO01257.1 - 0.0002 21.3 0.0 0.78 9.6 0.0 4.1 3 0 0 3 3 3 1 FANCI solenoid 2 TFCD_C PF12612.3 EDO01257.1 - 0.0027 17.1 8.9 0.44 9.9 0.6 5.7 6 1 0 6 6 6 2 Tubulin folding cofactor D C terminal XPC-binding PF09280.6 EDO01257.1 - 0.049 13.0 1.5 24 4.5 0.0 4.9 5 0 0 5 5 5 0 XPC-binding domain MMS19_C PF12460.3 EDO01257.1 - 0.12 11.0 15.5 1.6 7.3 0.0 6.4 6 2 2 8 8 8 0 RNAPII transcription regulator C-terminal HA2 PF04408.18 EDO01258.1 - 1.2e-17 63.8 0.0 4.4e-17 61.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDO01258.1 - 9e-12 44.6 0.0 2.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO01258.1 - 3e-09 36.5 0.0 7.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EDO01258.1 - 5.2e-08 32.6 0.0 1.9e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EDO01258.1 - 2.4e-07 30.9 0.0 7.7e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EDO01258.1 - 0.0049 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain KaiC PF06745.8 EDO01258.1 - 0.0067 15.5 0.2 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_29 PF13555.1 EDO01258.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDO01258.1 - 0.013 14.9 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EDO01258.1 - 0.016 15.5 0.1 0.073 13.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MARVEL PF01284.18 EDO01259.1 - 1.1e-24 86.9 12.7 1.4e-24 86.5 8.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF21 PF01595.15 EDO01259.1 - 0.086 12.1 3.7 0.51 9.5 2.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF21 Cys_Met_Meta_PP PF01053.15 EDO01260.1 - 5.3e-133 443.0 0.0 9.9e-131 435.5 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDO01260.1 - 7.7e-11 41.6 0.3 1.2e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EDO01260.1 - 6.1e-10 38.5 0.0 1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDO01260.1 - 1.4e-07 30.5 0.1 4.7e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDO01260.1 - 1.6e-05 24.2 0.0 2.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EDO01260.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 EDO01260.1 - 0.0044 15.5 0.0 0.0065 14.9 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Met_gamma_lyase PF06838.6 EDO01260.1 - 0.0091 14.3 0.1 0.013 13.8 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 EDO01260.1 - 0.015 14.0 0.0 0.044 12.5 0.0 1.8 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase AMP-binding PF00501.23 EDO01261.1 - 1.6e-80 270.5 0.0 2e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme E1-E2_ATPase PF00122.15 EDO01262.1 - 8.2e-63 211.5 5.3 2.3e-62 210.0 3.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO01262.1 - 2.4e-23 83.6 0.0 4.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO01262.1 - 1.3e-12 48.2 0.0 3.5e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO01262.1 - 2.4e-09 36.5 0.0 6.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDO01262.1 - 0.0014 18.2 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO01262.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RVT_1 PF00078.22 EDO01263.1 - 5.5e-24 84.7 0.1 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO01263.1 - 3e-17 62.8 0.3 9.4e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDO01263.1 - 5.4e-07 29.1 0.8 1.4e-06 27.8 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDO01263.1 - 0.00022 20.5 0.0 0.00048 19.4 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EDO01263.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EDO01263.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 EDO01264.1 - 5.2e-13 48.7 0.0 5.8e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01264.1 - 0.11 11.6 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DUF2012 PF09430.5 EDO01266.1 - 3.8e-26 91.3 0.0 4.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF3602 PF12223.3 EDO01268.1 - 0.0012 19.2 0.5 0.0012 19.2 0.3 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3602) UAA PF08449.6 EDO01269.1 - 8.1e-50 169.4 3.8 3e-46 157.7 0.9 2.0 1 1 1 2 2 2 2 UAA transporter family TPT PF03151.11 EDO01269.1 - 0.0069 16.0 7.1 0.0069 16.0 4.9 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EDO01269.1 - 0.011 15.9 1.3 0.03 14.5 0.9 1.8 1 0 0 1 1 1 0 Multidrug resistance efflux transporter EamA PF00892.15 EDO01269.1 - 0.84 9.6 13.5 0.29 11.1 6.4 2.5 2 1 0 2 2 2 0 EamA-like transporter family Cyclin PF08613.6 EDO01271.1 - 3.3e-28 98.9 0.0 4.3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDO01271.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EDO01272.1 - 2.3e-13 49.4 15.0 0.00046 19.9 0.1 7.7 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EDO01272.1 - 7.5e-07 28.7 12.1 1.4 9.2 0.1 8.2 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EDO01272.1 - 0.011 16.2 0.2 0.011 16.2 0.1 7.1 9 0 0 9 9 9 0 HEAT-like repeat Sugar_tr PF00083.19 EDO01273.1 - 1.7e-40 138.9 25.6 2.1e-40 138.6 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO01273.1 - 4.3e-18 65.1 29.6 4.3e-18 65.1 20.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Death_2 PF14786.1 EDO01274.1 - 0.00033 20.3 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Tube Death domain dCMP_cyt_deam_1 PF00383.17 EDO01275.1 - 2.1e-10 40.1 0.1 4.8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PUF PF00806.14 EDO01277.1 - 8.9e-57 185.5 14.2 5.8e-08 31.7 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.23 EDO01279.1 - 1e-115 386.5 0.2 1.5e-115 386.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO01279.1 - 1.1e-55 187.7 0.2 2.2e-55 186.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EDO01279.1 - 5.9e-29 100.1 0.7 1.5e-28 98.8 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EDO01279.1 - 2e-26 92.5 0.0 7.4e-26 90.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EDO01279.1 - 3e-23 81.4 0.1 7e-23 80.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDO01279.1 - 5.3e-19 67.7 0.0 1.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDO01279.1 - 1.1e-09 38.1 0.2 2.7e-09 36.8 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Peptidase_M49 PF03571.10 EDO01281.1 - 2.4e-100 336.2 0.0 6.8e-45 153.1 0.0 3.0 1 1 2 3 3 3 3 Peptidase family M49 IPP-2 PF04979.9 EDO01282.1 - 5.5e-09 36.3 6.3 4.9e-06 26.8 0.9 2.4 1 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF1510 PF07423.6 EDO01285.1 - 6.4e-10 38.7 25.7 8.9e-10 38.3 17.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EDO01285.1 - 0.00014 19.7 21.0 0.00014 19.7 14.5 1.1 1 0 0 1 1 1 1 Ycf1 Neur_chan_memb PF02932.11 EDO01285.1 - 0.00076 19.4 4.1 0.0009 19.2 2.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF262 PF03235.9 EDO01285.1 - 0.01 15.7 10.7 0.011 15.7 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SET PF00856.23 EDO01285.1 - 0.079 13.2 1.7 0.083 13.1 1.2 1.2 1 0 0 1 1 1 0 SET domain Presenilin PF01080.12 EDO01285.1 - 0.27 10.0 11.3 0.3 9.8 7.8 1.2 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.14 EDO01285.1 - 0.33 9.6 17.2 0.38 9.3 11.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.9 EDO01285.1 - 0.6 8.0 36.3 0.67 7.9 25.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CRT10 PF08728.5 EDO01285.1 - 2.1 6.2 6.5 2 6.3 4.5 1.1 1 0 0 1 1 1 0 CRT10 Herpes_DNAp_acc PF04929.7 EDO01285.1 - 2.9 6.7 20.1 3.4 6.5 13.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MIP-T3 PF10243.4 EDO01285.1 - 3.1 6.1 63.0 3.5 6.0 43.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SID-1_RNA_chan PF13965.1 EDO01285.1 - 3.7 5.6 12.3 8.2 4.4 8.5 1.6 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.8 EDO01285.1 - 4.8 5.7 13.2 4.8 5.7 9.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CENP-C_C PF11699.3 EDO01287.1 - 0.00038 20.3 0.0 0.00038 20.3 0.0 2.4 3 0 0 3 3 3 1 Mif2/CENP-C like Cupin_6 PF12852.2 EDO01287.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Cupin Macoilin PF09726.4 EDO01287.1 - 0.18 10.0 11.7 0.21 9.8 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 EDO01287.1 - 0.46 8.1 9.4 0.76 7.4 6.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1754 PF08555.5 EDO01287.1 - 7.1 7.2 29.3 5 7.7 12.6 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) GFO_IDH_MocA PF01408.17 EDO01289.1 - 2.3e-17 63.6 0.0 4.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2614 PF11023.3 EDO01290.1 - 0.42 10.4 7.4 0.44 10.3 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) DUF3671 PF12420.3 EDO01290.1 - 0.43 10.5 4.1 1 9.3 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function SRP54 PF00448.17 EDO01291.1 - 1.1e-75 253.4 3.7 1.8e-75 252.7 1.8 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EDO01291.1 - 3.3e-25 88.3 5.9 3.3e-25 88.3 4.1 4.8 4 2 2 6 6 5 1 Signal peptide binding domain SRP54_N PF02881.14 EDO01291.1 - 1.5e-13 50.6 0.5 4.4e-13 49.1 0.3 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EDO01291.1 - 3.2e-08 33.2 0.5 6.6e-08 32.1 0.1 1.7 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDO01291.1 - 1.2e-06 28.5 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDO01291.1 - 8.5e-06 25.5 0.0 2.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EDO01291.1 - 0.0003 20.2 0.1 0.00095 18.6 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EDO01291.1 - 0.0004 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EDO01291.1 - 0.00064 19.6 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO01291.1 - 0.001 19.9 0.0 0.0021 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EDO01291.1 - 0.0018 17.1 1.0 0.014 14.2 0.7 2.3 1 1 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EDO01291.1 - 0.0022 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 EDO01291.1 - 0.0033 17.1 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EDO01291.1 - 0.0034 16.7 0.0 0.009 15.4 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase ATP_bind_1 PF03029.12 EDO01291.1 - 0.015 14.8 0.2 0.093 12.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EDO01291.1 - 0.016 13.8 0.0 0.033 12.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EDO01291.1 - 0.021 15.1 0.1 0.072 13.3 0.0 2.0 2 1 0 2 2 1 0 AAA domain SRPRB PF09439.5 EDO01291.1 - 0.028 13.6 2.4 12 5.0 1.8 3.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.13 EDO01291.1 - 0.034 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 EDO01291.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EDO01291.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EDO01291.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Rrp15p PF07890.7 EDO01292.1 - 1e-38 132.3 8.4 1e-38 132.3 5.8 2.1 2 1 0 2 2 2 1 Rrp15p Daxx PF03344.10 EDO01292.1 - 6.2 5.1 25.5 8.3 4.7 17.6 1.1 1 0 0 1 1 1 0 Daxx Family Fer2 PF00111.22 EDO01293.1 - 2.2e-13 49.7 0.4 4.3e-13 48.8 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EDO01294.1 - 2.8e-15 55.7 3.6 0.00097 18.7 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein SCIMP PF15050.1 EDO01295.1 - 0.47 10.3 2.5 0.65 9.8 0.2 2.3 2 0 0 2 2 2 0 SCIMP protein DUF3671 PF12420.3 EDO01296.1 - 0.063 13.2 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Cytochrom_B_N PF00033.14 EDO01296.1 - 0.099 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB GATA PF00320.22 EDO01301.1 - 3.4e-06 26.2 7.5 6.5e-06 25.3 5.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Phage_GPO PF05929.6 EDO01301.1 - 0.094 11.9 0.4 0.17 11.0 0.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HTH_Tnp_Tc5 PF03221.11 EDO01302.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO01302.1 - 0.00014 21.1 0.1 0.00036 19.7 0.0 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF4290 PF14123.1 EDO01302.1 - 0.11 11.7 0.1 0.2 10.8 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4290) HTH_psq PF05225.11 EDO01303.1 - 3e-12 45.8 0.1 4.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO01303.1 - 6.9e-08 32.1 0.3 3.1e-07 30.1 0.0 2.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain NUMOD1 PF07453.8 EDO01303.1 - 0.00043 20.0 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 NUMOD1 domain HTH_23 PF13384.1 EDO01303.1 - 0.00046 19.7 0.4 0.16 11.6 0.0 2.5 2 1 1 3 3 3 2 Homeodomain-like domain SpoIIID PF12116.3 EDO01303.1 - 0.025 14.4 0.1 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_Tnp_1 PF01527.15 EDO01303.1 - 0.1 12.5 0.1 7.3 6.6 0.0 2.2 1 1 1 2 2 2 0 Transposase zf-CCHC PF00098.18 EDO01304.1 - 0.013 15.3 2.9 0.022 14.6 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF904 PF06005.7 EDO01304.1 - 0.023 14.9 0.4 0.023 14.9 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EDO01304.1 - 0.076 13.3 3.1 0.13 12.5 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) zinc_ribbon_2 PF13240.1 EDO01304.1 - 0.086 12.3 0.4 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-CCHC_4 PF14392.1 EDO01304.1 - 0.087 12.5 0.9 0.2 11.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EDO01304.1 - 0.094 12.2 1.3 0.25 10.8 0.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger OrfB_Zn_ribbon PF07282.6 EDO01304.1 - 0.12 12.0 1.2 0.21 11.2 0.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 EDO01304.1 - 0.24 10.9 2.2 0.29 10.6 0.4 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain bZIP_1 PF00170.16 EDO01304.1 - 0.55 10.2 6.0 0.1 12.5 1.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF3947 PF13135.1 EDO01305.1 - 0.0071 16.5 0.2 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3947) DUF2834 PF11196.3 EDO01305.1 - 0.12 12.5 1.4 0.58 10.3 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) Adap_comp_sub PF00928.16 EDO01306.1 - 1.3e-92 309.6 0.0 1.8e-92 309.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO01306.1 - 0.0012 18.5 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EDO01306.1 - 0.028 13.6 0.0 0.066 12.3 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.5 EDO01307.1 - 9.5e-87 291.6 2.8 1.3e-53 182.5 3.2 3.3 1 1 2 3 3 3 3 Transcription factor Opi1 Tn7_Tnp_TnsA_N PF08722.6 EDO01307.1 - 0.045 13.7 0.2 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 TnsA endonuclease N terminal DUF4429 PF14472.1 EDO01308.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) CFEM PF05730.6 EDO01309.1 - 1.9e-14 53.1 13.2 3e-14 52.5 9.1 1.3 1 0 0 1 1 1 1 CFEM domain AA_permease_2 PF13520.1 EDO01310.1 - 4.4e-42 144.0 51.2 5.5e-42 143.7 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO01310.1 - 6.8e-28 97.2 46.5 8.9e-28 96.8 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease zf-LITAF-like PF10601.4 EDO01310.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.4 4 1 0 4 4 4 0 LITAF-like zinc ribbon domain 2OG-FeII_Oxy_2 PF13532.1 EDO01312.1 - 1.3e-20 74.0 0.8 3.3e-20 72.7 0.5 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDO01312.1 - 4.6e-06 26.8 0.1 0.00021 21.4 0.0 2.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EDO01312.1 - 0.03 14.8 0.2 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Trypan_PARP PF05887.6 EDO01312.1 - 5.5 6.7 12.0 8.6 6.1 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATP-synt_ab PF00006.20 EDO01313.1 - 1.6e-113 377.5 0.0 2.1e-113 377.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO01313.1 - 2.4e-21 76.3 0.5 5.1e-21 75.2 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO01313.1 - 4.7e-15 55.5 4.9 1e-14 54.4 3.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain WD40 PF00400.27 EDO01314.1 - 2.9e-10 39.5 0.1 0.011 15.6 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat CLTH PF10607.4 EDO01314.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PfkB PF00294.19 EDO01315.1 - 2.7e-44 151.5 0.0 3.3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDO01315.1 - 0.0015 17.7 0.2 0.0022 17.2 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Dynamin_M PF01031.15 EDO01316.1 - 4.1e-105 350.8 1.0 8.1e-105 349.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EDO01316.1 - 9.2e-56 188.2 0.0 1.9e-55 187.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EDO01316.1 - 6.3e-29 99.7 5.1 1.3e-28 98.6 3.5 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDO01316.1 - 0.00029 20.7 1.7 0.0018 18.2 0.3 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EDO01316.1 - 0.0098 16.3 0.0 0.052 14.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Mito_fiss_reg PF05308.6 EDO01318.1 - 0.11 11.8 4.1 0.12 11.7 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CoA_transf_3 PF02515.12 EDO01319.1 - 3.4e-53 179.7 0.0 4.5e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.20 EDO01320.1 - 2.8e-17 63.1 0.1 4.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO01320.1 - 7.2e-09 35.5 0.1 1.1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDO01320.1 - 0.048 12.5 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribonuclease_T2 PF00445.13 EDO01321.1 - 3.2e-30 105.1 0.3 5.6e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Hap4_Hap_bind PF10297.4 EDO01322.1 - 1.9e-08 33.8 6.0 1.9e-08 33.8 4.2 1.9 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EDO01322.1 - 0.00014 21.6 12.5 0.00073 19.4 8.5 2.2 1 1 1 2 2 2 1 bZIP transcription factor COG2 PF06148.6 EDO01323.1 - 3.8e-27 94.7 0.0 4.9e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EDO01323.1 - 1.7e-05 24.5 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 IncA PF04156.9 EDO01323.1 - 0.0038 16.8 0.1 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 IncA protein DUF2450 PF10475.4 EDO01323.1 - 0.011 14.6 0.0 0.013 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EDO01323.1 - 0.064 11.8 0.1 0.081 11.5 0.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_L1 PF00687.16 EDO01324.1 - 2.6e-30 105.4 0.0 4e-30 104.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 EDO01325.1 - 1.5e-99 332.6 0.0 2.1e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDO01325.1 - 8.1e-42 142.8 0.9 1.7e-41 141.8 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EDO01325.1 - 0.034 13.2 1.6 0.083 11.9 1.1 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF3176 PF11374.3 EDO01326.1 - 0.017 15.0 1.8 0.023 14.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Formyl_trans_N PF00551.14 EDO01327.1 - 3.7e-24 85.2 0.0 6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase DUF1712 PF08217.6 EDO01328.1 - 2.6e-17 62.3 0.0 5.6e-15 54.6 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DPBB_1 PF03330.13 EDO01329.1 - 0.00015 21.6 0.8 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDO01329.1 - 0.0019 17.8 0.2 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 Barwin family Hexapep PF00132.19 EDO01331.1 - 1.4e-12 46.5 15.4 2e-07 30.1 1.6 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDO01331.1 - 2.1e-11 43.1 17.0 1.6e-06 27.5 2.6 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EDO01331.1 - 1.3e-09 37.9 0.0 2.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 EDO01331.1 - 7.6e-09 35.3 8.4 1.6e-08 34.3 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.1 EDO01331.1 - 0.35 11.1 0.1 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Asparaginase PF00710.15 EDO01334.1 - 0.016 14.0 0.0 0.017 14.0 0.0 1.0 1 0 0 1 1 1 0 Asparaginase DNA_pol3_delta PF06144.8 EDO01334.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase III, delta subunit HET PF06985.6 EDO01337.1 - 3.2e-20 72.7 0.0 1.1e-19 71.0 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EDO01337.1 - 1.4e-14 53.9 0.2 2.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01337.1 - 6.5e-05 22.1 0.1 0.00067 18.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DDE_1 PF03184.14 EDO01338.1 - 5.5e-23 81.2 0.2 4.4e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO01338.1 - 9.6e-12 44.5 0.0 3.8e-11 42.6 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DivIC PF04977.10 EDO01338.1 - 0.73 9.3 6.4 2.1 7.8 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator SPX PF03105.14 EDO01339.1 - 3.6e-06 26.9 0.3 6.3e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 SPX domain DUF4514 PF14986.1 EDO01339.1 - 0.13 12.1 0.4 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Mpp10 PF04006.7 EDO01341.1 - 1.7e-89 300.8 71.5 2.4e-87 293.7 49.5 2.2 1 1 0 1 1 1 1 Mpp10 protein AFG1_ATPase PF03969.11 EDO01342.1 - 2.4e-49 168.0 0.0 1.8e-25 89.5 0.0 4.0 2 2 0 4 4 4 2 AFG1-like ATPase AAA_5 PF07728.9 EDO01342.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO01342.1 - 3.5e-06 27.1 0.2 0.00028 20.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO01342.1 - 0.00034 20.7 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO01342.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDO01342.1 - 0.0047 16.6 0.1 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EDO01342.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 EDO01342.1 - 0.03 13.7 0.0 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EDO01342.1 - 0.032 14.5 0.3 0.78 10.0 0.0 2.6 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.1 EDO01342.1 - 0.037 13.5 0.0 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 EDO01342.1 - 0.048 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Methyltransf_17 PF12692.2 EDO01342.1 - 0.066 12.9 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase PIF1 PF05970.9 EDO01342.1 - 0.11 11.4 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.6 EDO01342.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Torsin Bac_DnaA PF00308.13 EDO01342.1 - 0.14 11.7 0.1 4.4 6.8 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein Nucleoporin_C PF03177.9 EDO01343.1 - 5.3e-123 411.5 12.6 8.6e-123 410.9 8.8 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDO01343.1 - 5.6e-84 282.3 0.0 7.8e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 EDO01344.1 - 2.6e-36 125.1 0.0 3.6e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01344.1 - 1.7e-14 53.5 0.0 2.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO01344.1 - 0.0089 15.7 0.0 0.57 9.8 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 EDO01345.1 - 4e-54 183.1 0.0 4.5e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Abhydrolase_3 PF07859.8 EDO01347.1 - 1.1e-40 139.4 0.0 1.3e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDO01347.1 - 1.4e-08 33.9 0.0 4.1e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EDO01347.1 - 0.00077 18.1 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDO01347.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO01347.1 - 0.035 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Macro PF01661.16 EDO01348.1 - 1.2e-26 92.8 0.0 2.4e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain RNA_ligase PF09414.5 EDO01349.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 RNA ligase DUF4646 PF15496.1 EDO01350.1 - 1.8e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) COMP PF11598.3 EDO01352.1 - 1.4 9.0 4.1 0.27 11.3 0.4 1.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Aminotran_1_2 PF00155.16 EDO01353.1 - 6.9e-89 298.3 0.0 7.8e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_17 PF13207.1 EDO01354.1 - 1.3e-05 25.9 0.0 1.9e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO01354.1 - 0.00059 20.1 0.0 0.0075 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EDO01354.1 - 0.00093 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 EDO01354.1 - 0.026 14.5 0.0 0.058 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EDO01354.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ADH_zinc_N PF00107.21 EDO01357.1 - 6.8e-24 83.8 0.1 1.2e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO01357.1 - 2.8e-19 70.2 0.0 6.4e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO01357.1 - 9.6e-12 44.6 0.0 6.4e-11 41.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain APG6 PF04111.7 EDO01359.1 - 0.094 11.7 13.6 0.18 10.8 9.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 EDO01359.1 - 0.94 9.8 15.5 0.33 11.2 7.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF904) IncA PF04156.9 EDO01359.1 - 0.96 9.0 11.5 2.2 7.8 8.0 1.6 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EDO01359.1 - 6.2 6.6 11.0 15 5.3 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-C2H2_4 PF13894.1 EDO01361.1 - 0.0012 19.0 17.8 1.2 9.5 0.6 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO01361.1 - 0.43 11.0 18.0 4.3 7.8 0.2 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EDO01361.1 - 1.6 9.1 12.4 1.7 9.0 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EDO01361.1 - 9.8 6.3 13.5 4 7.5 3.9 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) TF_Zn_Ribbon PF08271.7 EDO01362.1 - 0.093 12.0 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding NAD_binding_10 PF13460.1 EDO01364.1 - 2.1e-10 40.8 0.0 1.6e-09 38.0 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EDO01364.1 - 5.1e-10 39.1 0.1 7.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EDO01364.1 - 1.7e-08 33.9 0.2 0.00017 20.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.14 EDO01364.1 - 2.9e-08 32.7 0.2 1.3e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RTA1 PF04479.8 EDO01366.1 - 1.9e-18 66.8 8.9 2.3e-18 66.5 6.1 1.0 1 0 0 1 1 1 1 RTA1 like protein TPT PF03151.11 EDO01366.1 - 0.017 14.7 0.9 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family YrhK PF14145.1 EDO01366.1 - 6.8 6.4 8.9 1.8 8.3 0.2 2.8 3 0 0 3 3 3 0 YrhK-like protein APOC4 PF15119.1 EDO01367.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein C4 Cupin_2 PF07883.6 EDO01369.1 - 4.7e-09 35.6 0.0 1.3e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EDO01369.1 - 0.00014 21.1 0.0 0.00029 20.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EDO01369.1 - 0.0061 15.9 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Cupin OTU PF02338.14 EDO01370.1 - 6.3e-19 68.7 3.0 9.6e-19 68.1 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDO01370.1 - 0.00027 20.3 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain IFT43 PF15305.1 EDO01370.1 - 0.0045 17.0 3.0 0.0045 17.0 2.1 2.3 1 1 1 2 2 2 1 Intraflagellar transport protein 43 SOBP PF15279.1 EDO01370.1 - 1.9 8.7 6.8 2.4 8.4 4.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4355 PF14265.1 EDO01370.1 - 2.6 8.0 24.1 6 6.8 7.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) TMEM247 PF15444.1 EDO01370.1 - 5.2 6.8 12.4 1.1 8.9 5.6 1.8 1 1 1 2 2 2 0 Transmembrane protein 247 TORC_M PF12885.2 EDO01370.1 - 6.6 6.4 6.5 2.7 7.7 0.5 2.2 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain TPMT PF05724.6 EDO01371.1 - 1.6e-17 63.6 0.0 2.1e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EDO01371.1 - 0.00012 21.7 0.7 0.00052 19.6 0.5 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO01371.1 - 0.00022 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO01371.1 - 0.00059 20.4 0.0 0.00095 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01371.1 - 0.00066 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EDO01371.1 - 0.00083 18.5 0.2 0.0019 17.4 0.1 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB AdoMet_MTase PF07757.8 EDO01371.1 - 0.0039 17.2 0.2 0.0056 16.7 0.2 1.4 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_12 PF08242.7 EDO01371.1 - 0.035 14.5 0.4 0.17 12.3 0.3 2.0 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EDO01372.1 - 1.6e-28 99.7 0.0 2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO01372.1 - 1.9e-24 86.7 0.0 2.6e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO01372.1 - 9.2e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 KR domain Gly-zipper_OmpA PF13436.1 EDO01376.1 - 0.0062 16.1 18.8 0.17 11.5 0.1 5.1 5 0 0 5 5 5 3 Glycine-zipper containing OmpA-like membrane domain NAD_binding_8 PF13450.1 EDO01376.1 - 0.25 11.4 4.8 4.7 7.3 0.0 3.9 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Mcp5_PH PF12814.2 EDO01378.1 - 2.1e-48 163.2 0.0 5.2e-48 162.0 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EDO01378.1 - 0.056 13.1 15.8 0.02 14.6 4.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PSRP-3_Ycf65 PF04839.8 EDO01378.1 - 0.18 11.8 0.8 0.42 10.6 0.6 1.6 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) GAS PF13851.1 EDO01378.1 - 0.24 10.5 16.1 1.7 7.8 5.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 EDO01378.1 - 1.3 9.0 13.3 3.1 7.7 9.2 1.6 1 0 0 1 1 1 0 Fez1 ADIP PF11559.3 EDO01378.1 - 4.3 7.2 15.4 18 5.1 10.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding PALP PF00291.20 EDO01380.1 - 1.5e-54 185.2 0.0 1e-53 182.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDO01380.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.7 EDO01381.1 - 5.5e-47 159.1 0.1 8.1e-47 158.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EDO01381.1 - 3.5e-44 150.2 0.0 5.3e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EDO01381.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EDO01381.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UQ_con PF00179.21 EDO01382.1 - 5e-39 132.9 0.0 7.2e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO01382.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 EDO01382.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Chitin_synth_1 PF01644.12 EDO01383.1 - 1.2e-67 226.7 0.0 1.8e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDO01383.1 - 5.2e-28 96.5 0.0 9.8e-28 95.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDO01383.1 - 1.9e-24 85.9 0.0 3.5e-20 71.9 0.0 2.8 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO01383.1 - 7e-11 42.1 0.2 7e-11 42.1 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO01383.1 - 2.4e-07 30.8 0.0 7.1e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Syndecan PF01034.15 EDO01384.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Ras PF00071.17 EDO01385.1 - 9.9e-37 125.8 0.0 2.2e-36 124.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO01385.1 - 7.5e-11 42.5 0.0 3e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EDO01385.1 - 0.03 13.7 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HTH_Tnp_Tc5 PF03221.11 EDO01386.1 - 0.00035 20.3 0.1 0.00042 20.0 0.1 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AATase PF07247.7 EDO01386.1 - 0.045 12.2 0.0 0.049 12.1 0.0 1.0 1 0 0 1 1 1 0 Alcohol acetyltransferase DUF3238 PF11579.3 EDO01387.1 - 0.021 14.4 0.1 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3238) DUF3984 PF13136.1 EDO01389.1 - 4.4e-75 252.9 12.3 7e-75 252.2 8.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) IKI3 PF04762.7 EDO01390.1 - 0 1081.9 0.1 0 1077.1 0.0 2.1 1 1 0 1 1 1 1 IKI3 family WD40 PF00400.27 EDO01390.1 - 0.03 14.2 0.1 60 3.7 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat KOW PF00467.24 EDO01391.1 - 1.7e-08 33.8 3.3 3.3e-08 32.9 2.3 1.5 1 0 0 1 1 1 1 KOW motif DUF4208 PF13907.1 EDO01391.1 - 0.042 14.0 0.5 0.1 12.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) MAP7 PF05672.6 EDO01391.1 - 0.51 9.7 19.8 0.17 11.2 6.2 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Ras PF00071.17 EDO01392.1 - 1.6e-54 183.6 0.0 1.9e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO01392.1 - 7.9e-16 58.6 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO01392.1 - 5.4e-07 29.0 0.0 8.6e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO01392.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDO01392.1 - 0.034 13.2 0.0 0.04 13.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EDO01392.1 - 0.1 12.0 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_S30 PF01577.11 EDO01395.1 - 0.035 13.4 1.6 0.067 12.5 1.1 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease zf-PHD-like PF15446.1 EDO01396.1 - 1.8e-71 239.0 10.3 3.4e-71 238.1 7.1 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EDO01396.1 - 7.4e-57 192.4 0.0 1.3e-56 191.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EDO01396.1 - 2e-14 53.1 0.9 4.7e-14 51.8 0.6 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EDO01396.1 - 1.7e-13 50.1 0.0 5.7e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 EDO01396.1 - 1.3e-08 34.3 4.3 0.00059 19.4 0.7 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EDO01396.1 - 2.1e-05 24.1 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EDO01396.1 - 0.00017 21.2 19.1 0.00032 20.3 2.4 3.4 4 0 0 4 4 4 2 PHD-finger ResIII PF04851.10 EDO01396.1 - 0.012 15.4 0.0 0.042 13.6 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-ribbon_3 PF13248.1 EDO01396.1 - 2.1 7.6 6.2 9.6 5.5 4.3 2.1 1 0 0 1 1 1 0 zinc-ribbon domain SpoU_methylase PF00588.14 EDO01397.1 - 5.5e-27 94.3 0.0 1e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EDO01397.1 - 4.1e-08 33.2 0.1 1.2e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Actin PF00022.14 EDO01398.1 - 4.5e-131 436.9 0.0 5.1e-131 436.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO01398.1 - 0.013 14.1 0.0 0.27 9.7 0.0 2.6 1 1 0 1 1 1 0 MreB/Mbl protein DUF4050 PF13259.1 EDO01401.1 - 6.9e-36 122.8 0.4 1.9e-35 121.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) SR-25 PF10500.4 EDO01402.1 - 0.004 16.6 22.9 0.0046 16.4 15.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pex16 PF08610.5 EDO01402.1 - 2.8 6.8 7.3 3.4 6.5 5.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Cut8_M PF14483.1 EDO01405.1 - 0.032 14.0 0.1 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Cut8 dimerisation domain RGS PF00615.14 EDO01406.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Tn916-Xis PF09035.5 EDO01409.1 - 0.069 13.2 0.0 0.89 9.6 0.0 2.9 3 1 0 3 3 3 0 Excisionase from transposon Tn916 TYA PF01021.14 EDO01409.1 - 1.4 9.2 5.3 1.3 9.2 1.0 2.2 1 1 1 2 2 2 0 TYA transposon protein DUF1507 PF07408.6 EDO01410.1 - 0.019 14.6 0.7 0.073 12.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1507) DUF1500 PF07389.7 EDO01410.1 - 0.064 13.2 0.2 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) BPL_LplA_LipB PF03099.14 EDO01411.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EDO01412.1 - 2.5e-126 420.8 0.0 3.2e-126 420.4 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase TPR_12 PF13424.1 EDO01413.1 - 0.087 12.7 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat HET PF06985.6 EDO01414.1 - 3.2e-09 37.0 0.0 5.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_pol_A_exo1 PF01612.15 EDO01416.1 - 1.4e-08 34.4 0.0 2.9e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Aa_trans PF01490.13 EDO01417.1 - 2.1e-66 224.1 23.2 2.4e-66 223.8 16.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EDO01417.1 - 0.0028 16.2 24.1 0.0035 15.9 16.7 1.2 1 0 0 1 1 1 1 Amino acid permease RRM_1 PF00076.17 EDO01418.1 - 8.9e-13 47.6 0.0 2.5e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO01418.1 - 7.3e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO01418.1 - 5.5e-08 32.5 0.1 1.7e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO01418.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1499 PF07386.6 EDO01418.1 - 3 8.0 8.0 1.2 9.2 0.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1499) WD40 PF00400.27 EDO01419.1 - 4.8e-31 105.5 0.3 5.1e-10 38.8 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EDO01419.1 - 0.00015 20.0 0.1 0.00016 19.9 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO01419.1 - 0.00038 20.2 0.7 0.071 12.8 0.0 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EDO01419.1 - 0.0006 18.7 0.2 0.14 10.9 0.0 2.3 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 EDO01419.1 - 0.0016 17.9 1.0 0.023 14.1 0.6 2.3 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EDO01419.1 - 0.0067 15.2 0.1 0.013 14.2 0.1 1.6 1 1 0 1 1 1 1 Nup133 N terminal like Gmad1 PF10647.4 EDO01419.1 - 0.12 11.7 1.8 0.54 9.6 0.4 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain FTHFS PF01268.14 EDO01420.1 - 4.1e-257 853.6 0.1 5.4e-257 853.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EDO01420.1 - 3.5e-69 230.9 0.3 3.5e-69 230.9 0.2 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EDO01420.1 - 8.5e-39 132.2 1.0 2e-38 131.0 0.7 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 EDO01420.1 - 0.013 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.22 EDO01420.1 - 0.052 12.9 0.5 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SPX PF03105.14 EDO01423.1 - 1.3e-51 175.9 0.9 2e-51 175.4 0.6 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EDO01423.1 - 3.1e-31 108.7 39.1 4.8e-31 108.1 27.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EDO01423.1 - 7.8e-14 51.0 24.5 7.8e-14 51.0 17.0 2.3 1 1 1 2 2 2 2 Citrate transporter Phosphoesterase PF04185.9 EDO01425.1 - 1.5e-35 123.1 2.7 5.2e-35 121.3 1.9 1.7 1 1 0 1 1 1 1 Phosphoesterase family TMF_DNA_bd PF12329.3 EDO01426.1 - 0.011 15.5 0.4 0.031 14.0 0.2 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nop14 PF04147.7 EDO01427.1 - 5.9 4.6 31.7 9 4.0 21.9 1.2 1 0 0 1 1 1 0 Nop14-like family PAPA-1 PF04795.7 EDO01429.1 - 8.7e-27 93.6 2.6 8.7e-27 93.6 1.8 3.6 4 2 0 4 4 4 1 PAPA-1-like conserved region CCDC50_N PF15295.1 EDO01429.1 - 3.2 7.6 15.9 2.1 8.2 3.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Plasmodium_Vir PF05795.6 EDO01429.1 - 3.4 6.7 9.0 1.7 7.7 0.6 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Pex14_N PF04695.8 EDO01430.1 - 5.4e-30 104.2 0.0 9.4e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1284 PF06935.6 EDO01431.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) SLAC1 PF03595.12 EDO01436.1 - 3.6e-13 48.8 0.8 4.4e-13 48.5 0.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel PET PF06297.9 EDO01437.1 - 0.13 11.9 0.1 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 PET Domain MARVEL PF01284.18 EDO01438.1 - 3.7e-25 88.4 22.1 4.6e-25 88.1 15.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4149 PF13664.1 EDO01438.1 - 0.47 10.5 11.0 0.16 12.0 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) NUP PF06516.6 EDO01442.1 - 1.8e-66 224.0 0.1 2.2e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Kelch_5 PF13854.1 EDO01445.1 - 2.5e-13 49.6 12.8 5.6e-12 45.3 0.6 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 EDO01445.1 - 1.5e-06 28.1 16.4 0.05 13.7 0.2 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO01445.1 - 2.5e-06 27.1 18.4 0.0033 17.1 0.6 5.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EDO01445.1 - 0.015 14.7 12.0 0.67 9.5 0.1 4.8 5 0 0 5 5 5 0 Kelch motif DUF2668 PF10873.3 EDO01445.1 - 0.069 13.3 0.2 0.069 13.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Shisa PF13908.1 EDO01445.1 - 0.31 11.2 6.7 12 6.0 5.5 2.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Kelch_6 PF13964.1 EDO01445.1 - 6.5 7.1 23.4 3.8 7.8 0.9 4.8 3 2 2 5 5 5 0 Kelch motif Oxidored_FMN PF00724.15 EDO01446.1 - 3.5e-73 246.5 0.0 1.6e-72 244.4 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_S3_C PF00189.15 EDO01446.1 - 0.034 14.3 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain 2-Hacid_dh_C PF02826.14 EDO01447.1 - 1e-41 142.0 0.0 1.3e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDO01447.1 - 0.0037 17.6 0.0 0.0089 16.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.25 EDO01447.1 - 0.0083 15.6 0.0 0.0099 15.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FAD_binding_3 PF01494.14 EDO01447.1 - 0.017 14.2 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EDO01447.1 - 0.027 14.1 0.1 0.08 12.6 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EDO01447.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EDO01447.1 - 0.037 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO01447.1 - 0.042 12.7 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF974 PF06159.8 EDO01448.1 - 1.2e-90 303.3 0.0 1.4e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) SET PF00856.23 EDO01449.1 - 0.089 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 SET domain KH_1 PF00013.24 EDO01450.1 - 4.2e-11 42.3 0.0 1.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EDO01450.1 - 3.4e-06 26.5 0.9 0.0006 19.4 0.1 2.9 2 0 0 2 2 2 2 KH domain ALS_ss_C PF10369.4 EDO01451.1 - 3.5e-18 65.0 0.0 3.1e-17 62.0 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EDO01451.1 - 2.5e-13 49.2 0.1 4.3e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EDO01451.1 - 1.3e-09 37.6 0.0 2.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.20 EDO01455.1 - 3.1e-15 56.0 0.0 1.1e-14 54.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01455.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PPR_2 PF13041.1 EDO01456.1 - 6.8e-15 54.7 2.2 0.00051 19.9 0.1 5.3 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.15 EDO01456.1 - 5.2e-08 32.3 14.7 0.014 15.3 0.0 6.2 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 EDO01456.1 - 1e-06 28.5 6.2 0.75 10.2 0.0 6.4 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EDO01456.1 - 0.029 13.8 9.2 0.81 9.2 0.3 4.7 4 1 0 4 4 4 0 PPR repeat Patched PF02460.13 EDO01456.1 - 0.054 11.4 0.0 0.099 10.5 0.0 1.4 1 0 0 1 1 1 0 Patched family MRP-S25 PF13741.1 EDO01457.1 - 8.3e-51 172.6 14.0 7.2e-31 107.4 1.6 3.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 Alg14 PF08660.6 EDO01458.1 - 5.7e-19 68.7 0.0 1e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like YbjM PF11045.3 EDO01458.1 - 0.022 14.4 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Ima1_N PF09779.4 EDO01459.1 - 8.5e-27 94.2 5.4 8.5e-27 94.2 3.7 1.7 2 0 0 2 2 2 1 Ima1 N-terminal domain LRR_8 PF13855.1 EDO01460.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeat Y_phosphatase2 PF03162.8 EDO01462.1 - 5.6e-45 152.6 0.0 8.2e-45 152.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDO01462.1 - 2.9e-12 47.1 0.0 5.5e-10 39.7 0.0 2.4 1 1 1 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 EDO01462.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO01462.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2416 PF10315.4 EDO01463.1 - 5.5e-06 26.5 0.7 1.4e-05 25.2 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) DUF1977 PF09320.6 EDO01464.1 - 6.9e-26 90.5 0.0 1.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EDO01464.1 - 8e-22 76.7 0.3 1.6e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Ufd2P_core PF10408.4 EDO01465.1 - 2.6e-205 683.3 5.6 3.3e-205 683.0 3.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EDO01465.1 - 2.6e-21 75.3 5.1 4.8e-21 74.4 0.7 3.1 3 0 0 3 3 3 1 U-box domain OmpH PF03938.9 EDO01465.1 - 0.0044 16.9 3.0 0.14 12.0 0.5 2.6 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Asp PF00026.18 EDO01466.1 - 3.4e-58 197.3 6.2 4.8e-58 196.8 4.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO01466.1 - 6e-09 36.0 0.4 6e-09 36.0 0.3 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO01466.1 - 0.035 14.6 0.5 0.52 10.8 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease T2SI PF02501.12 EDO01468.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I PPTA PF01239.17 EDO01469.1 - 3.8e-11 41.8 5.0 3e-05 23.1 0.1 4.2 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.9 EDO01470.1 - 3.2e-50 169.9 1.7 3.9e-50 169.6 1.2 1.1 1 0 0 1 1 1 1 CHD5-like protein WXG100 PF06013.7 EDO01470.1 - 0.018 15.0 2.0 0.033 14.1 1.4 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG PgaD PF13994.1 EDO01470.1 - 4.1 6.8 6.2 2.2 7.7 2.6 1.8 1 1 1 2 2 2 0 PgaD-like protein GRAB PF10375.4 EDO01472.1 - 1.5e-07 30.7 1.0 3.1e-07 29.7 0.7 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EDO01472.1 - 9.6e-06 24.9 23.3 0.003 16.7 0.7 3.9 2 1 2 4 4 4 2 Reovirus sigma C capsid protein Filament PF00038.16 EDO01472.1 - 2.3e-05 24.0 56.0 9.3e-05 22.0 20.9 3.6 1 1 3 4 4 4 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 EDO01472.1 - 0.00018 21.4 56.6 0.0087 15.9 11.1 4.1 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EDO01472.1 - 0.0003 20.6 11.1 0.024 14.4 1.0 3.5 2 2 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Transposase_22 PF02994.9 EDO01472.1 - 0.0012 17.3 13.8 0.0012 17.3 9.6 3.1 1 1 2 3 3 3 1 L1 transposable element Bacillus_HBL PF05791.6 EDO01472.1 - 0.0045 16.3 2.8 0.0045 16.3 1.9 4.2 2 1 2 4 4 3 1 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 EDO01472.1 - 0.0054 16.5 23.8 0.17 11.6 0.8 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF1664) SlyX PF04102.7 EDO01472.1 - 0.0072 16.6 0.9 0.0072 16.6 0.6 5.2 4 2 0 4 4 3 1 SlyX FlaC_arch PF05377.6 EDO01472.1 - 0.0088 15.9 21.6 0.075 12.9 0.7 6.1 3 2 0 4 4 4 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EDO01472.1 - 0.049 13.7 28.8 0.35 10.9 4.4 4.1 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 EDO01472.1 - 0.15 9.7 60.2 0.0047 14.7 19.2 2.2 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 EDO01472.1 - 0.24 10.9 60.1 0.029 13.9 16.0 3.9 1 1 3 4 4 4 0 IncA protein HOOK PF05622.7 EDO01472.1 - 0.42 8.3 47.4 0.73 7.5 25.2 2.2 1 1 1 2 2 2 0 HOOK protein NPV_P10 PF05531.7 EDO01472.1 - 0.71 10.1 15.9 5.8 7.2 0.5 4.8 2 2 4 6 6 6 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.11 EDO01472.1 - 0.72 9.9 40.8 0.26 11.3 6.0 3.8 2 1 1 3 3 3 0 Flagellar FliJ protein ApoO PF09769.4 EDO01472.1 - 1.3 8.7 17.1 0.97 9.1 0.5 4.0 1 1 3 4 4 4 0 Apolipoprotein O ATG16 PF08614.6 EDO01472.1 - 1.4 8.7 59.8 3.9 7.2 8.4 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EDO01472.1 - 2.2 6.8 46.0 0.014 14.1 10.2 3.7 1 1 2 3 3 2 0 Spc7 kinetochore protein DUF4618 PF15397.1 EDO01472.1 - 2.5 7.3 41.9 1.1 8.4 7.6 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.7 EDO01472.1 - 2.6 7.8 60.7 0.69 9.6 14.5 5.2 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein HR1 PF02185.11 EDO01472.1 - 3.1 7.6 31.2 0.53 10.0 0.4 5.6 3 2 2 5 5 5 0 Hr1 repeat PspA_IM30 PF04012.7 EDO01472.1 - 3.3 7.0 43.7 0.87 8.9 16.4 4.4 1 1 3 4 4 4 0 PspA/IM30 family DUF948 PF06103.6 EDO01472.1 - 3.6 7.5 12.4 0.51 10.2 0.4 4.5 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 EDO01472.1 - 7.9 3.6 58.3 0.13 9.5 14.5 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) p450 PF00067.17 EDO01474.1 - 0.00033 19.2 0.0 0.00036 19.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DENN PF02141.16 EDO01476.1 - 2.4e-57 193.6 0.1 3.7e-57 193.0 0.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EDO01476.1 - 2.1e-17 62.8 0.0 4.6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EDO01476.1 - 1.6e-09 37.6 0.2 4e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 dDENN domain rRNA_proc-arch PF13234.1 EDO01477.1 - 4.6e-102 340.7 0.0 1e-101 339.6 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EDO01477.1 - 1.6e-62 209.9 1.1 3.2e-62 208.9 0.7 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDO01477.1 - 1.4e-21 76.6 0.0 4.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO01477.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO01477.1 - 0.0027 17.5 0.0 0.035 13.9 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EDO01477.1 - 0.0042 16.0 0.0 0.009 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Prp19 PF08606.6 EDO01477.1 - 0.051 13.3 3.0 0.6 9.8 0.1 3.1 3 0 0 3 3 3 0 Prp19/Pso4-like AAA_19 PF13245.1 EDO01477.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain COX7C PF02935.11 EDO01478.1 - 2.6e-17 62.3 0.4 3.1e-17 62.1 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Med18 PF09637.5 EDO01479.1 - 6.1e-67 225.7 0.0 6.9e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Mit_ribos_Mrp51 PF11709.3 EDO01479.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF2638 PF10937.3 EDO01480.1 - 2.6e-39 134.6 0.4 3.2e-39 134.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EDO01481.1 - 1.8e-101 338.5 0.8 2.6e-101 338.0 0.5 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.12 EDO01482.1 - 2.6e-84 282.8 0.0 2.9e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EDO01483.1 - 5.2e-11 42.4 2.1 3.9e-10 39.6 0.4 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF3248 PF11609.3 EDO01483.1 - 0.011 15.4 0.6 0.085 12.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3248) GHMP_kinases_C PF08544.8 EDO01483.1 - 0.016 15.3 0.3 1 9.5 0.0 3.0 3 0 0 3 3 3 0 GHMP kinases C terminal C1_3 PF07649.7 EDO01484.1 - 0.1 12.6 1.6 0.53 10.3 0.6 2.0 2 0 0 2 2 2 0 C1-like domain Lyase_1 PF00206.15 EDO01487.1 - 1.3e-72 244.6 0.0 1.9e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EDO01487.1 - 1.7e-26 92.0 0.0 3.8e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Vfa1 PF08432.5 EDO01488.1 - 9.1e-61 205.0 19.9 1e-60 204.8 13.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SET PF00856.23 EDO01488.1 - 0.18 12.0 3.0 0.22 11.8 2.0 1.1 1 0 0 1 1 1 0 SET domain Astro_capsid PF03115.9 EDO01488.1 - 0.23 9.6 8.5 0.29 9.3 5.9 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4407 PF14362.1 EDO01488.1 - 0.26 10.1 12.2 0.31 9.9 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0560 PF10577.4 EDO01488.1 - 0.45 8.7 9.2 0.55 8.4 6.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Merozoite_SPAM PF07133.6 EDO01488.1 - 0.48 10.3 23.9 0.64 9.8 16.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CMV_1a PF12467.3 EDO01488.1 - 0.61 10.4 13.3 0.86 9.9 9.2 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family U79_P34 PF03064.11 EDO01488.1 - 0.75 9.2 20.4 0.97 8.9 14.1 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EDO01488.1 - 1.4 8.2 24.0 1.8 7.8 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4246 PF14033.1 EDO01488.1 - 1.9 7.0 10.7 2.8 6.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) LMBR1 PF04791.11 EDO01488.1 - 2.6 6.5 6.2 2.9 6.3 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.12 EDO01488.1 - 3.1 7.5 8.3 4.1 7.1 5.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 EDO01488.1 - 3.2 6.8 9.6 3.9 6.5 6.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EDO01488.1 - 3.4 5.5 20.2 4.4 5.2 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein G0-G1_switch_2 PF15103.1 EDO01488.1 - 4.5 7.5 7.9 2.4e+02 2.0 5.5 2.2 1 1 0 1 1 1 0 G0/G1 switch protein 2 Ycf1 PF05758.7 EDO01488.1 - 5.5 4.5 15.6 6.2 4.4 10.8 1.0 1 0 0 1 1 1 0 Ycf1 NPR3 PF03666.8 EDO01488.1 - 5.9 5.2 12.0 7.2 5.0 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 EDO01488.1 - 7.8 4.0 12.5 9.4 3.7 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TP53IP5 PF15331.1 EDO01488.1 - 8.6 6.2 13.7 12 5.7 9.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DSPc PF00782.15 EDO01489.1 - 4.1e-21 74.9 0.0 8.8e-21 73.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO01489.1 - 0.073 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2 PF00096.21 EDO01494.1 - 0.0035 17.5 23.0 0.037 14.3 0.6 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDO01494.1 - 0.023 14.8 0.9 0.023 14.8 0.6 3.2 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EDO01494.1 - 0.037 14.3 23.8 0.23 11.8 1.1 4.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO01494.1 - 0.041 14.1 0.4 0.041 14.1 0.3 3.6 4 1 0 4 4 4 0 Zinc-finger double domain zf-CHCC PF10276.4 EDO01494.1 - 0.28 11.0 3.5 4.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain GOLGA2L5 PF15070.1 EDO01496.1 - 0.0058 15.1 8.3 0.0068 14.9 5.8 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF4197 PF13852.1 EDO01496.1 - 0.023 14.2 3.0 0.032 13.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) NosD PF05048.8 EDO01496.1 - 0.032 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) V_ATPase_I PF01496.14 EDO01496.1 - 0.088 10.6 6.0 0.094 10.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Viral_P18 PF04521.8 EDO01496.1 - 0.1 12.0 4.0 0.23 10.8 2.7 1.6 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3450 PF11932.3 EDO01496.1 - 0.12 11.6 10.7 0.14 11.3 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Rootletin PF15035.1 EDO01496.1 - 0.18 11.8 13.1 0.24 11.3 9.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion EMP24_GP25L PF01105.19 EDO01496.1 - 0.32 10.6 4.5 0.55 9.9 3.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 EDO01496.1 - 0.34 11.2 11.5 0.12 12.7 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EDO01496.1 - 0.34 9.8 9.5 0.47 9.3 6.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EDO01496.1 - 0.62 9.9 14.6 0.33 10.8 8.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EDO01496.1 - 3.2 6.7 14.9 5.2 6.0 10.3 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EDO01496.1 - 5.5 6.8 16.3 7.1 6.5 5.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF3595 PF12166.3 EDO01497.1 - 0.022 13.5 0.2 0.022 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Hpt PF01627.18 EDO01497.1 - 0.21 11.5 1.9 2.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Hpt domain Conotoxin PF02950.12 EDO01499.1 - 0.85 10.4 3.0 0.99 10.2 2.1 1.2 1 0 0 1 1 1 0 Conotoxin AcetylCoA_hydro PF02550.10 EDO01500.1 - 8.5e-47 159.4 0.0 1.4e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EDO01500.1 - 1.5e-39 135.1 0.0 2.8e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Ndc1_Nup PF09531.5 EDO01501.1 - 5.4e-182 606.3 0.1 6.8e-182 606.0 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SNARE PF05739.14 EDO01502.1 - 9.2e-19 66.8 1.8 2.5e-18 65.5 1.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 EDO01502.1 - 2.5e-13 49.9 7.3 6.9e-13 48.5 0.3 2.4 2 0 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 EDO01502.1 - 2e-05 24.2 4.2 0.00067 19.2 0.2 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 EDO01502.1 - 0.00053 20.1 1.7 0.00053 20.1 1.2 2.5 1 1 0 2 2 2 1 Syntaxin ALIX_LYPXL_bnd PF13949.1 EDO01502.1 - 0.012 14.5 5.7 0.037 12.9 3.8 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF1664 PF07889.7 EDO01502.1 - 0.012 15.3 3.3 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 EDO01502.1 - 0.11 12.9 7.2 0.17 12.2 0.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.16 EDO01502.1 - 0.11 12.0 4.9 0.2 11.2 2.0 2.3 2 1 0 2 2 2 0 Synaptobrevin NPV_P10 PF05531.7 EDO01502.1 - 0.14 12.4 1.5 1.9 8.7 0.3 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.8 EDO01502.1 - 0.14 10.4 2.5 3.6 5.8 0.0 2.2 2 1 0 2 2 2 0 Tweety RmuC PF02646.11 EDO01502.1 - 0.33 9.7 4.4 0.51 9.1 0.2 2.3 2 1 0 2 2 2 0 RmuC family TMCO5 PF14992.1 EDO01502.1 - 0.35 9.9 6.5 0.88 8.6 4.5 1.6 1 1 0 1 1 1 0 TMCO5 family DUF3708 PF12501.3 EDO01502.1 - 0.69 9.7 2.8 1.7 8.4 0.4 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Mnd1 PF03962.10 EDO01502.1 - 2.3 7.8 6.0 0.81 9.3 0.4 2.0 1 1 1 2 2 2 0 Mnd1 family V-SNARE PF05008.10 EDO01502.1 - 2.6 8.2 5.5 0.86 9.8 0.3 2.9 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BMFP PF04380.8 EDO01502.1 - 8.7 6.5 9.8 9.2 6.4 2.3 3.1 3 1 1 4 4 3 0 Membrane fusogenic activity Rtt106 PF08512.7 EDO01503.1 - 5.4e-25 87.2 0.0 9.5e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like bPH_2 PF03703.9 EDO01503.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain PNK3P PF08645.6 EDO01508.1 - 1.1e-16 60.6 0.6 4.2e-11 42.5 0.0 2.4 1 1 1 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EDO01508.1 - 1.4e-10 41.2 0.1 3.2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain Kinesin PF00225.18 EDO01511.1 - 1.8e-61 207.6 0.5 3.8e-61 206.6 0.1 1.8 1 1 0 1 1 1 1 Kinesin motor domain FtsK_SpoIIIE PF01580.13 EDO01511.1 - 0.00058 19.3 0.3 1.3 8.5 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_24 PF13479.1 EDO01511.1 - 0.0024 17.5 0.6 0.011 15.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO01511.1 - 0.14 12.3 2.0 0.7 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDO01511.1 - 0.17 11.7 0.1 0.17 11.7 0.0 4.4 3 2 1 4 4 4 0 Domain of unknown function DUF87 AAA_16 PF13191.1 EDO01511.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain CDP-OH_P_tran_2 PF08009.6 EDO01513.1 - 0.093 12.4 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 DUF4423 PF14394.1 EDO01513.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF1500 PF07389.7 EDO01513.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) RhoGAP PF00620.22 EDO01515.1 - 2.4e-41 140.8 0.0 1.5e-40 138.2 0.0 2.2 1 1 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EDO01515.1 - 3.1e-10 40.1 3.8 5.6e-10 39.2 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SpaB_C PF14028.1 EDO01515.1 - 0.038 13.5 1.5 0.08 12.4 1.0 1.6 1 0 0 1 1 1 0 SpaB C-terminal domain Strumpellin PF10266.4 EDO01515.1 - 0.074 10.4 0.5 0.12 9.7 0.4 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin DUF3399 PF11879.3 EDO01515.1 - 0.16 12.2 5.1 3.9 7.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Med12 PF09497.5 EDO01517.1 - 9.4e-28 95.9 0.2 9.7e-27 92.7 0.2 2.3 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 UPF0139 PF03669.8 EDO01518.1 - 0.00029 20.2 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.17 EDO01519.1 - 2e-28 98.0 4.7 3.1e-28 97.4 3.3 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 EDO01519.1 - 0.018 14.9 2.7 0.024 14.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) VCX_VCY PF15231.1 EDO01519.1 - 0.035 14.4 3.4 0.035 14.4 2.4 1.6 2 0 0 2 2 2 0 Variable charge X/Y family MBA1 PF07961.6 EDO01521.1 - 1.6e-15 56.6 0.1 2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EDO01521.1 - 3.4e-07 30.3 0.2 6.2e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Tim44-like domain Peptidase_S7 PF00949.16 EDO01521.1 - 0.046 13.1 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease RRM_1 PF00076.17 EDO01522.1 - 2.1e-30 104.1 0.3 1.2e-15 56.8 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO01522.1 - 4.5e-20 71.3 0.1 9.1e-13 47.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO01522.1 - 8.7e-11 41.5 1.6 2.5e-06 27.2 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CEP1-DNA_bind PF09287.5 EDO01522.1 - 0.024 14.0 0.5 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 CEP-1, DNA binding SAICAR_synt PF01259.13 EDO01523.1 - 5.8e-12 45.2 0.0 6.4e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.7 EDO01524.1 - 2.3e-36 124.9 0.0 2.8e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 EDO01525.1 - 4.3e-34 116.2 5.8 7.7e-34 115.4 2.9 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EDO01525.1 - 0.086 12.7 6.2 0.98 9.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat COX6A PF02046.10 EDO01526.1 - 9e-15 54.6 0.2 9.4e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.18 EDO01527.1 - 5.6e-15 55.9 0.0 8.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDO01527.1 - 1.1e-14 54.0 0.0 3.7e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase CDC27 PF09507.5 EDO01527.1 - 0.082 12.1 5.4 0.13 11.4 3.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 rRNA_proc-arch PF13234.1 EDO01528.1 - 0.02 14.0 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain STIL_N PF15253.1 EDO01528.1 - 0.15 10.7 0.3 0.94 8.1 0.0 1.9 1 1 1 2 2 2 0 SCL-interrupting locus protein N-terminus MAT_Alpha1 PF04769.7 EDO01529.1 - 5.2e-24 84.6 0.0 8e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box PF00505.14 EDO01531.1 - 4.5e-16 58.8 0.7 9.9e-16 57.7 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box ANTH PF07651.11 EDO01532.1 - 3.3e-72 242.5 0.0 3.3e-72 242.5 0.0 2.5 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EDO01532.1 - 1.4e-59 200.4 4.9 1.4e-59 200.4 3.4 4.9 5 0 0 5 5 5 2 I/LWEQ domain Med15 PF09606.5 EDO01532.1 - 0.39 8.8 35.8 0.82 7.7 24.8 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2404 PF10296.4 EDO01533.1 - 2.2e-31 107.8 0.0 5.1e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EDO01533.1 - 0.052 13.7 0.0 0.22 11.7 0.0 2.1 1 1 0 1 1 1 0 PH domain DNA_pol_B PF00136.16 EDO01534.1 - 3.1e-71 240.5 0.1 4.4e-70 236.7 0.0 2.4 2 1 1 3 3 3 1 DNA polymerase family B zf-C4pol PF14260.1 EDO01534.1 - 6.4e-18 64.5 6.3 6.4e-18 64.5 4.4 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 EDO01534.1 - 2.1e-14 53.1 0.0 5.8e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-CHY PF05495.7 EDO01534.1 - 0.95 9.6 4.1 2.3 8.4 2.9 1.6 1 0 0 1 1 1 0 CHY zinc finger Slu7 PF11708.3 EDO01536.1 - 5.9e-78 261.9 17.9 5.9e-78 261.9 12.4 1.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EDO01536.1 - 0.012 15.2 0.7 0.023 14.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EDO01536.1 - 0.13 12.2 1.5 0.24 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S4 PF00163.14 EDO01537.1 - 7e-29 100.0 0.8 7e-29 100.0 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO01537.1 - 2.6e-12 45.9 1.3 2.6e-12 45.9 0.9 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EDO01538.1 - 4.1e-39 132.3 7.0 4.2e-39 132.3 3.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L21e Wax2_C PF12076.3 EDO01538.1 - 0.057 13.1 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain Herpes_gI PF01688.12 EDO01539.1 - 0.092 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Sec2p PF06428.6 EDO01540.1 - 2.5e-23 81.8 18.5 2.5e-23 81.8 12.8 2.7 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Asparaginase_2 PF01112.13 EDO01540.1 - 0.27 9.9 1.9 4.9 5.7 0.1 2.2 2 0 0 2 2 2 0 Asparaginase PRP21_like_P PF12230.3 EDO01541.1 - 2.3e-58 197.3 22.0 6.3e-58 195.9 15.2 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EDO01541.1 - 1.7e-38 130.0 1.6 1.7e-18 65.9 0.1 2.4 2 0 0 2 2 2 2 Surp module SET PF00856.23 EDO01543.1 - 3.9e-17 63.0 2.6 6.5e-16 59.0 0.2 3.2 2 1 0 2 2 2 1 SET domain Mito_carr PF00153.22 EDO01544.1 - 8.3e-73 240.1 0.9 6.6e-24 83.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EDO01545.1 - 1.3e-25 89.3 0.0 1.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 PX domain Tetraspannin PF00335.15 EDO01546.1 - 2.6e-06 26.8 0.9 3.8e-06 26.3 0.6 1.2 1 0 0 1 1 1 1 Tetraspanin family Zn_clus PF00172.13 EDO01547.1 - 0.051 13.4 11.8 0.098 12.5 8.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 EDO01549.1 - 3.7e-13 49.1 0.0 1.3e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO01549.1 - 1.9e-12 46.5 0.4 3.8e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO01549.1 - 1.1e-09 37.9 0.0 2.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDO01549.1 - 0.031 14.2 0.1 0.081 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EDO01549.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease NUMOD1 PF07453.8 EDO01549.1 - 0.071 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 NUMOD1 domain HTH_23 PF13384.1 EDO01549.1 - 1.5 8.5 3.6 0.61 9.8 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain zf-DHHC PF01529.15 EDO01550.1 - 1.3e-39 135.3 0.6 1.9e-39 134.8 0.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EDO01550.1 - 0.026 14.0 1.5 0.039 13.4 1.0 1.1 1 0 0 1 1 1 0 Yip1 domain PSI PF01437.20 EDO01550.1 - 0.054 13.6 5.1 0.12 12.6 3.5 1.5 1 0 0 1 1 1 0 Plexin repeat PMT PF02366.13 EDO01552.1 - 2.8e-74 249.5 15.5 5.6e-74 248.5 10.7 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO01552.1 - 1.9e-53 180.8 0.1 3.1e-53 180.1 0.1 1.3 1 0 0 1 1 1 1 MIR domain PLA2_B PF01735.13 EDO01555.1 - 4e-118 394.6 2.7 5.2e-118 394.3 1.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ribosomal_L36 PF00444.13 EDO01556.1 - 3.7e-19 68.4 7.1 6e-19 67.7 4.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR PF05347.10 EDO01557.1 - 8.6e-19 67.0 0.6 1.7e-18 66.1 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDO01557.1 - 2.8e-18 65.8 0.9 3.2e-18 65.6 0.1 1.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EDO01557.1 - 0.015 15.7 0.1 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.19 EDO01558.1 - 7.8e-14 51.4 0.5 1.2e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO01558.1 - 5.9e-09 35.9 0.1 1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO01558.1 - 8.5e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO01558.1 - 0.00048 20.2 0.0 0.00077 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO01558.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EDO01558.1 - 0.0085 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO01558.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PLAC8 PF04749.12 EDO01559.1 - 0.022 15.3 0.1 0.022 15.3 0.1 1.1 1 0 0 1 1 1 0 PLAC8 family MFS_1 PF07690.11 EDO01562.1 - 5.9e-12 44.9 35.6 2.7e-06 26.3 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO01562.1 - 1.2e-05 24.1 5.9 8.1e-05 21.3 0.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Abhydrolase_6 PF12697.2 EDO01564.1 - 1.1e-10 41.7 0.2 2.6e-10 40.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO01564.1 - 6.9e-10 38.8 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO01564.1 - 3.9e-06 26.2 0.0 1.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EDO01564.1 - 8.6e-06 25.4 0.1 1.3e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EDO01564.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDO01564.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Cutinase PF01083.17 EDO01564.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase NMT_C PF02799.10 EDO01565.1 - 1.5e-79 265.8 0.0 2.2e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EDO01565.1 - 3.3e-77 257.6 0.0 6.8e-77 256.6 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EDO01565.1 - 3.7e-06 26.8 0.0 6.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO01565.1 - 0.0026 17.9 0.0 0.0084 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RhoGAP PF00620.22 EDO01565.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain MFS_1 PF07690.11 EDO01566.1 - 8.8e-34 116.7 33.7 8.8e-34 116.7 23.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO01566.1 - 6.5e-15 54.6 10.0 6.5e-15 54.6 6.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDO01566.1 - 8.3e-05 20.9 5.3 0.00012 20.4 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2534 PF10749.4 EDO01566.1 - 0.032 14.1 0.5 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Fungal_trans PF04082.13 EDO01567.1 - 2.3e-30 105.3 4.3 3.8e-30 104.6 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO01567.1 - 3.7e-07 29.9 14.3 9.3e-07 28.6 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 EDO01567.1 - 0.1 12.2 0.2 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 Telomerase_RBD PF12009.3 EDO01568.1 - 2.8e-14 53.1 0.0 5.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EDO01568.1 - 0.0085 15.4 0.0 0.029 13.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 EDO01569.1 - 7e-28 97.7 0.0 1.6e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EDO01569.1 - 1.9e-07 30.8 0.1 3.9e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 BAR domain Abhydrolase_5 PF12695.2 EDO01570.1 - 5.1e-22 78.1 0.0 6.5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO01570.1 - 2.9e-16 60.0 0.0 8.8e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO01570.1 - 1.3e-06 27.7 0.0 3.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EDO01570.1 - 4.8e-06 26.1 0.0 1.6e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EDO01570.1 - 8.9e-06 25.2 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EDO01570.1 - 3.3e-05 22.5 0.1 0.9 7.9 0.1 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 EDO01570.1 - 0.0001 21.1 0.0 0.00013 20.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_1 PF00561.15 EDO01570.1 - 0.0004 20.0 0.0 0.015 14.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EDO01570.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EDO01570.1 - 0.0085 15.8 0.0 0.16 11.6 0.0 2.6 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EDO01570.1 - 0.035 13.4 0.0 0.37 10.0 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EDO01570.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 EDO01570.1 - 0.15 11.6 0.2 0.39 10.2 0.0 1.9 2 1 0 2 2 2 0 PGAP1-like protein RPA_C PF08784.6 EDO01571.1 - 0.083 13.3 0.4 0.083 13.3 0.3 2.6 3 0 0 3 3 3 0 Replication protein A C terminal zf-LYAR PF08790.6 EDO01571.1 - 0.12 12.0 0.3 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger HisG PF01634.13 EDO01573.1 - 9.1e-33 113.1 0.3 4.4e-31 107.6 0.2 2.4 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EDO01573.1 - 5.7e-27 93.4 0.7 1.1e-26 92.5 0.5 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EDO01573.1 - 0.0029 17.2 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 NMT1/THI5 like zf-NF-X1 PF01422.12 EDO01575.1 - 1.9e-07 30.8 51.7 3.6e-05 23.6 7.5 9.9 11 0 0 11 11 11 6 NF-X1 type zinc finger R3H PF01424.17 EDO01576.1 - 1.7e-16 59.6 0.1 3.3e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 R3H domain Nodulin_late PF07127.6 EDO01577.1 - 0.064 13.3 0.4 0.064 13.3 0.2 1.1 1 0 0 1 1 1 0 Late nodulin protein DHDPS PF00701.17 EDO01578.1 - 7.6e-38 129.7 0.0 9.4e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 EDO01580.1 - 9.3e-28 96.9 30.3 2.6e-15 55.9 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDO01580.1 - 3.4e-05 22.4 23.4 0.00022 19.7 2.4 2.8 1 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EDO01580.1 - 0.0003 19.5 23.3 0.012 14.2 16.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EDO01580.1 - 2.9 5.8 10.1 0.42 8.6 1.3 3.0 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 EDO01581.1 - 7.1e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2406 PF10295.4 EDO01581.1 - 0.059 13.8 1.2 0.15 12.5 0.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) Zn_clus PF00172.13 EDO01581.1 - 0.17 11.8 5.4 0.09 12.6 2.4 1.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_1 PF00536.25 EDO01583.1 - 0.00061 19.9 0.0 0.00078 19.5 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UBA_4 PF14555.1 EDO01583.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain NDT80_PhoG PF05224.7 EDO01584.1 - 2.6e-31 109.0 0.0 6.3e-31 107.8 0.0 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Hira PF07569.6 EDO01586.1 - 3.9e-84 281.2 0.0 6e-84 280.6 0.0 1.3 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EDO01586.1 - 4.7e-18 64.3 11.7 3.8e-07 29.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat HIRA_B PF09453.5 EDO01586.1 - 1e-11 44.0 0.7 1.9e-11 43.1 0.5 1.5 1 0 0 1 1 1 1 HIRA B motif Glycos_transf_1 PF00534.15 EDO01587.1 - 5.6e-13 48.6 0.0 9.4e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.11 EDO01589.1 - 4.1e-14 52.0 15.6 5.8e-14 51.5 10.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDO01589.1 - 1.3e-13 50.6 5.4 1.3e-13 50.6 3.7 2.5 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 DUF1122 PF06557.6 EDO01589.1 - 0.024 13.8 0.2 0.041 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) DEAD PF00270.24 EDO01590.1 - 3.3e-21 75.5 0.0 1.6e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO01590.1 - 7.1e-21 74.8 0.4 3e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO01590.1 - 7.8e-19 67.3 0.1 2.3e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO01590.1 - 0.0077 15.0 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain CRISPR_Cas2 PF09827.4 EDO01590.1 - 0.023 14.8 0.0 0.69 10.0 0.0 3.0 2 0 0 2 2 2 0 CRISPR associated protein Cas2 DUF2161 PF09929.4 EDO01590.1 - 0.046 13.6 0.8 0.43 10.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2161) AAA_22 PF13401.1 EDO01590.1 - 0.076 13.1 0.0 0.35 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDO01590.1 - 0.094 11.6 0.0 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SBF PF01758.11 EDO01591.1 - 3.6e-32 111.2 8.7 3.6e-32 111.2 6.0 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family Proteasome PF00227.21 EDO01592.1 - 7e-28 97.2 0.0 8.4e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EDO01593.1 - 7.5e-34 115.6 1.1 1.2e-33 114.9 0.8 1.3 1 0 0 1 1 1 1 HCNGP-like protein Pkinase PF00069.20 EDO01594.1 - 7.1e-76 254.7 0.0 1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01594.1 - 2.2e-35 121.9 0.0 3.8e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDO01594.1 - 2.7e-16 59.4 0.2 5.4e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EDO01594.1 - 2.2e-10 39.9 0.0 2.3e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDO01594.1 - 0.00096 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO01594.1 - 0.039 13.0 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDO01594.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EDO01594.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family SIS PF01380.17 EDO01595.1 - 2e-55 185.9 0.2 4.6e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EDO01595.1 - 2.2e-27 95.7 0.0 2.7e-18 65.8 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDO01595.1 - 1.7e-19 70.0 0.0 3.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDO01595.1 - 2.5e-11 43.3 0.0 5.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDO01595.1 - 1.5e-06 27.1 0.0 2.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EDO01595.1 - 0.032 13.9 0.0 0.29 10.8 0.0 2.4 2 1 0 2 2 2 0 SIS domain AAA PF00004.24 EDO01596.1 - 5e-43 146.4 0.0 8.9e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO01596.1 - 9.1e-08 32.2 0.0 3.6e-06 27.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EDO01596.1 - 1.9e-06 27.6 0.1 3.8e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO01596.1 - 2.4e-06 27.5 0.0 7.8e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDO01596.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO01596.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EDO01596.1 - 0.00026 19.9 0.0 0.00063 18.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDO01596.1 - 0.00032 20.4 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDO01596.1 - 0.0004 21.1 0.8 0.0021 18.8 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO01596.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDO01596.1 - 0.0017 17.1 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDO01596.1 - 0.0019 18.0 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EDO01596.1 - 0.0024 18.1 0.2 0.0082 16.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDO01596.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO01596.1 - 0.0036 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDO01596.1 - 0.0051 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EDO01596.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EDO01596.1 - 0.0074 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EDO01596.1 - 0.0082 15.5 0.1 0.046 13.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EDO01596.1 - 0.0094 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EDO01596.1 - 0.021 14.4 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EDO01596.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EDO01596.1 - 0.024 13.7 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 EDO01596.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EDO01596.1 - 0.027 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EDO01596.1 - 0.027 14.1 0.0 0.13 11.8 0.0 2.2 2 1 0 2 2 1 0 Archaeal ATPase PhoH PF02562.11 EDO01596.1 - 0.029 13.6 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF4200 PF13863.1 EDO01596.1 - 0.03 14.2 0.4 0.085 12.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 EDO01596.1 - 0.035 14.4 0.5 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDO01596.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EDO01596.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EDO01596.1 - 0.055 13.0 0.1 0.44 10.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDO01596.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EDO01596.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Enolase_C PF00113.17 EDO01597.1 - 4.1e-154 511.8 0.1 5.5e-154 511.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EDO01597.1 - 1.9e-57 192.8 0.4 3.8e-57 191.8 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EDO01597.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 EDO01597.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain eIF3_subunit PF08597.5 EDO01598.1 - 8.1e-70 235.1 34.4 9.1e-70 235.0 23.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Vpu PF00558.14 EDO01598.1 - 1 8.9 3.9 3.2 7.3 2.7 1.9 1 0 0 1 1 1 0 Vpu protein 4HBT_3 PF13622.1 EDO01599.1 - 2.8e-50 171.4 0.1 3.3e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EDO01599.1 - 0.0047 17.0 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Mito_fiss_reg PF05308.6 EDO01599.1 - 7.9 5.7 6.7 9.4 5.5 2.2 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator ArfGap PF01412.13 EDO01600.1 - 5.1e-32 110.1 1.7 9e-32 109.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EDO01600.1 - 2.1e-13 50.3 0.7 5.3e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 PH domain EMP24_GP25L PF01105.19 EDO01600.1 - 3.2 7.4 6.7 0.91 9.2 2.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD C2 PF00168.25 EDO01601.1 - 3.2e-11 42.9 0.0 6.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF2183 PF09949.4 EDO01601.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Methyltransf_25 PF13649.1 EDO01605.1 - 7.2e-05 23.0 0.0 0.00024 21.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01605.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3306 PF11748.3 EDO01607.1 - 0.031 14.9 10.8 0.047 14.3 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Astro_capsid PF03115.9 EDO01607.1 - 0.047 11.9 3.7 0.05 11.8 2.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DBINO PF13892.1 EDO01607.1 - 0.14 12.1 2.9 0.22 11.5 2.0 1.4 1 0 0 1 1 1 0 DNA-binding domain Sporozoite_P67 PF05642.6 EDO01607.1 - 0.16 9.8 6.3 0.16 9.8 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EDO01607.1 - 0.4 8.5 24.2 0.42 8.4 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EDO01607.1 - 1.6 7.3 23.8 1.9 7.1 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.9 EDO01607.1 - 1.8 8.0 10.9 2.2 7.7 7.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 EDO01607.1 - 3.8 6.8 19.2 4.7 6.5 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VID27 PF08553.5 EDO01607.1 - 3.8 5.6 15.3 4.1 5.5 10.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 EDO01607.1 - 4.6 6.4 18.3 5.6 6.1 12.7 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.8 EDO01607.1 - 4.6 6.7 27.0 5.3 6.5 18.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.7 EDO01607.1 - 5.3 6.0 23.8 6.9 5.7 16.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spore_coat_CotO PF14153.1 EDO01607.1 - 6.3 6.2 12.0 9.1 5.6 8.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Sigma70_ner PF04546.8 EDO01607.1 - 8 6.0 17.2 16 5.0 11.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.6 EDO01607.1 - 8.1 5.8 20.1 9.8 5.6 13.9 1.1 1 0 0 1 1 1 0 PPP4R2 Opacity PF02462.10 EDO01608.1 - 0.095 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Opacity family porin protein DDE_1 PF03184.14 EDO01609.1 - 5.9e-34 117.1 1.3 1.3e-23 83.2 0.1 3.1 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO01609.1 - 5.5e-06 26.1 0.0 1.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO01609.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO01609.1 - 0.011 15.5 6.7 0.028 14.3 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DPBB_1 PF03330.13 EDO01610.1 - 4e-11 42.7 0.1 1.4e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDO01610.1 - 0.00028 20.5 0.2 0.00062 19.4 0.1 1.6 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.16 EDO01610.1 - 0.00049 19.8 1.2 0.00095 18.9 0.8 1.5 1 0 0 1 1 1 1 Pollen allergen TALPID3 PF15324.1 EDO01610.1 - 0.19 9.0 10.1 0.21 8.9 7.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Ribosomal_60s PF00428.14 EDO01610.1 - 0.34 11.3 5.3 0.71 10.3 3.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bac_luciferase PF00296.15 EDO01611.1 - 2e-61 207.7 0.0 2.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 EDO01612.1 - 4.3e-08 32.7 0.0 9e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO01612.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EDO01613.1 - 6.2e-27 94.2 0.1 3.1e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 PDR_CDR PF06422.7 EDO01615.1 - 3.7e-25 87.5 0.0 6.5e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 EDO01615.1 - 5.3e-05 23.5 0.2 0.11 12.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PGPGW PF09656.5 EDO01615.1 - 0.063 12.5 0.3 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) DUF4470 PF14737.1 EDO01617.1 - 2.6e-24 84.8 0.0 4.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EDO01617.1 - 1.7e-09 37.4 13.3 3.3e-09 36.4 9.2 1.5 1 0 0 1 1 1 1 MYND finger NUC173 PF08161.7 EDO01617.1 - 0.11 11.8 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 NUC173 domain IBR PF01485.16 EDO01618.1 - 3.2e-08 33.3 4.3 3.2e-08 33.3 3.0 3.1 3 0 0 3 3 3 1 IBR domain zf-RING_2 PF13639.1 EDO01618.1 - 0.00073 19.3 9.1 0.00073 19.3 6.3 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO01618.1 - 0.0017 18.0 7.7 0.0017 18.0 5.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO01618.1 - 0.0065 16.4 11.0 0.0065 16.4 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EDO01618.1 - 0.01 15.5 0.8 0.024 14.3 0.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 EDO01618.1 - 0.011 15.4 10.7 0.011 15.4 7.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO01618.1 - 1.9 8.3 12.7 0.15 11.8 4.9 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Lipase_GDSL PF00657.17 EDO01620.1 - 1.3e-10 41.5 0.1 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDO01620.1 - 2.1e-06 27.9 1.0 4.2e-06 27.0 0.6 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DAHP_synth_2 PF01474.11 EDO01621.1 - 2.7e-194 645.5 0.0 3.1e-194 645.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Vpu PF00558.14 EDO01623.1 - 2.1 7.9 6.3 17 5.0 0.1 3.0 2 1 0 2 2 2 0 Vpu protein adh_short PF00106.20 EDO01624.1 - 7.6e-27 94.2 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO01624.1 - 5e-10 39.3 0.0 7.5e-10 38.7 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDO01624.1 - 0.0037 16.7 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDO01624.1 - 0.0057 16.4 0.6 0.015 15.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EDO01625.1 - 7.3e-30 104.5 0.0 8.7e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO01625.1 - 6e-28 97.8 1.0 8.1e-28 97.4 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO01625.1 - 6.1e-16 58.6 0.5 8.8e-16 58.0 0.3 1.1 1 0 0 1 1 1 1 KR domain UbiA PF01040.13 EDO01630.1 - 4.7e-39 134.1 17.6 7.1e-39 133.5 12.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family SKIP_SNW PF02731.10 EDO01631.1 - 2.7 7.4 6.8 3.5 7.0 4.7 1.1 1 0 0 1 1 1 0 SKIP/SNW domain Myb_DNA-bind_6 PF13921.1 EDO01632.1 - 8.4e-06 25.7 0.5 5.1e-05 23.2 0.3 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_Rpb2_3 PF04565.11 EDO01633.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Pkinase PF00069.20 EDO01640.1 - 6e-11 41.9 0.0 8.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDO01640.1 - 2e-08 34.2 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO01640.1 - 7.5e-07 28.4 0.0 9.9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EDO01640.1 - 8.4e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDO01640.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EDO01640.1 - 0.002 17.7 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EDO01640.1 - 0.0024 16.8 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like EcKinase PF02958.15 EDO01640.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase WaaY PF06176.6 EDO01640.1 - 0.038 13.2 0.7 0.051 12.7 0.1 1.4 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 EDO01640.1 - 0.083 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 NUP PF06516.6 EDO01641.1 - 3.4e-130 433.4 0.0 4.1e-130 433.1 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) HTH_psq PF05225.11 EDO01642.1 - 1.1e-09 37.6 0.1 2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO01642.1 - 4.6e-07 29.5 0.4 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO01642.1 - 2.1e-05 23.8 1.3 0.00038 19.6 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF3404 PF11884.3 EDO01642.1 - 0.023 13.5 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HTH_28 PF13518.1 EDO01642.1 - 0.035 14.1 0.5 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDO01642.1 - 0.037 13.8 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 NUMOD1 domain HTH_29 PF13551.1 EDO01642.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.1 EDO01642.1 - 0.097 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EDO01642.1 - 0.098 12.3 0.5 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc5 PF03221.11 EDO01644.1 - 3.9e-05 23.3 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF904 PF06005.7 EDO01644.1 - 0.046 14.0 1.0 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EDO01644.1 - 0.071 13.4 1.1 0.19 12.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DDE_1 PF03184.14 EDO01644.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 EDO01645.1 - 4.7e-35 120.8 0.6 1e-34 119.7 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO01645.1 - 9.4e-15 55.1 0.0 2.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDO01645.1 - 0.01 16.1 0.2 0.038 14.2 0.0 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EDO01645.1 - 0.045 13.3 0.4 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DDE_1 PF03184.14 EDO01646.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO01646.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO01646.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO01646.1 - 4.2e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO01646.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EDO01647.1 - 7.4e-15 54.5 29.3 1.1e-14 53.9 19.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO01647.1 - 1.9e-07 29.6 16.5 5.8e-07 28.0 11.5 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.1 EDO01647.1 - 0.006 16.5 0.8 0.006 16.5 0.6 3.4 4 1 0 4 4 4 1 Protein of unknown function (DUF4231) PrgI PF12666.2 EDO01647.1 - 0.077 13.1 0.6 0.077 13.1 0.4 3.6 2 1 2 4 4 4 0 PrgI family protein ADH_zinc_N PF00107.21 EDO01648.1 - 2.7e-10 39.8 0.0 5.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO01648.1 - 0.0056 16.4 0.1 0.25 11.0 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EDO01649.1 - 1e-09 37.4 0.1 1.1e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1451 PF07295.6 EDO01649.1 - 0.22 11.2 0.9 1.9 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) PS-DH PF14765.1 EDO01650.1 - 4.1e-17 62.2 0.0 5.3e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EDO01650.1 - 2.9e-05 24.4 0.0 6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01650.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO01650.1 - 0.03 14.9 0.0 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EDO01650.1 - 0.03 13.3 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EDO01650.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase KR PF08659.5 EDO01652.1 - 1.4e-50 171.4 0.0 4e-50 169.9 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EDO01652.1 - 2.4e-40 138.1 0.0 1.9e-38 132.0 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EDO01652.1 - 3.5e-28 98.1 0.0 7.7e-27 93.7 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EDO01652.1 - 3.7e-25 88.1 0.4 2.8e-24 85.2 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme Condensation PF00668.15 EDO01652.1 - 1.6e-22 79.7 0.4 3.1e-13 49.2 0.1 2.3 1 1 1 2 2 2 2 Condensation domain HxxPF_rpt PF13745.1 EDO01652.1 - 1.9e-11 44.0 0.0 5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 EDO01652.1 - 2.4e-05 23.1 0.0 0.00014 20.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDO01652.1 - 0.00029 20.3 0.0 0.0028 17.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family HET PF06985.6 EDO01653.1 - 7.3e-25 87.7 0.0 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Enterotoxin_b PF01376.13 EDO01653.1 - 0.0034 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Heat-labile enterotoxin beta chain Peptidase_S49_N PF08496.5 EDO01654.1 - 0.52 10.0 15.0 0.56 9.9 10.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 EDO01654.1 - 1 9.2 9.4 1.1 9.1 6.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3899 PF13038.1 EDO01654.1 - 1.2 9.2 6.5 1.3 9.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF1777 PF08648.7 EDO01654.1 - 1.4 8.5 21.0 1.6 8.4 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) ALS2CR8 PF15299.1 EDO01654.1 - 1.7 8.1 14.0 1.8 8.0 9.7 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 NinG PF05766.7 EDO01654.1 - 2.7 7.6 13.7 2.7 7.6 9.5 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF1510 PF07423.6 EDO01654.1 - 2.9 7.2 10.1 3 7.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PEX11 PF05648.9 EDO01654.1 - 3.1 6.9 5.3 3 7.0 3.7 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2413 PF10310.4 EDO01654.1 - 3.4 6.4 7.1 3.3 6.4 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Topoisom_I_N PF02919.10 EDO01654.1 - 4.5 6.5 12.9 6.3 6.0 8.9 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF1764 PF08576.5 EDO01654.1 - 5.3 7.8 14.1 5.7 7.7 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3464 PF11947.3 EDO01654.1 - 5.3 6.4 9.4 5.4 6.4 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4207 PF13904.1 EDO01654.1 - 5.8 6.2 19.1 5.9 6.1 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF2058 PF09831.4 EDO01654.1 - 6.2 6.6 12.3 6.3 6.6 8.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Fmp27 PF10344.4 EDO01654.1 - 6.6 4.2 8.3 6.5 4.2 5.7 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2828 PF11443.3 EDO01654.1 - 7.8 4.5 7.6 7.2 4.6 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_pol_Rpc4 PF05132.9 EDO01654.1 - 8.4 6.3 8.2 8.7 6.3 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PcfJ PF14284.1 EDO01654.1 - 9.6 5.6 11.0 10 5.5 7.6 1.0 1 0 0 1 1 1 0 PcfJ-like protein AAA_19 PF13245.1 EDO01657.1 - 0.00018 21.1 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EDO01657.1 - 0.0042 16.7 0.0 0.0044 16.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EDO01657.1 - 0.0084 15.4 0.0 0.009 15.3 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EDO01657.1 - 0.058 12.9 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EDO01657.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Amidoligase_2 PF12224.3 EDO01661.1 - 2.4e-42 145.2 0.0 3e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Glyco_hydro_71 PF03659.9 EDO01663.1 - 2.5e-135 450.8 10.0 3e-135 450.6 6.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Nop14 PF04147.7 EDO01664.1 - 2.5e-281 935.4 30.3 3.1e-281 935.1 21.0 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 EDO01664.1 - 0.024 13.5 0.1 0.055 12.3 0.1 1.5 1 0 0 1 1 1 0 Noc2p family Peptidase_S9 PF00326.16 EDO01665.1 - 1.4e-57 194.3 0.4 6.9e-57 192.0 0.1 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDO01665.1 - 1.4e-08 34.5 0.0 2.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDO01665.1 - 0.00027 19.5 0.2 0.022 13.2 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) TMEM154 PF15102.1 EDO01666.1 - 0.0012 18.5 2.6 0.002 17.8 1.8 1.3 1 0 0 1 1 1 1 TMEM154 protein family DAP10 PF07213.6 EDO01666.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 DAP10 membrane protein ABC2_membrane_3 PF12698.2 EDO01666.1 - 0.012 14.7 0.4 0.014 14.4 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_gE PF02480.11 EDO01666.1 - 0.016 13.5 0.4 0.019 13.2 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 EDO01666.1 - 0.02 15.2 12.1 0.032 14.5 8.4 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Peptidase_M56 PF05569.6 EDO01666.1 - 0.032 13.2 0.3 0.042 12.8 0.2 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Glycophorin_A PF01102.13 EDO01666.1 - 0.032 13.9 5.9 0.063 13.0 4.1 1.5 1 0 0 1 1 1 0 Glycophorin A Syndecan PF01034.15 EDO01666.1 - 0.061 12.9 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Mucin PF01456.12 EDO01666.1 - 0.092 12.5 18.9 0.13 12.0 13.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF515 PF04415.7 EDO01666.1 - 8.6 4.4 10.3 12 4.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HEAT_2 PF13646.1 EDO01667.1 - 0.0017 18.6 0.0 0.0046 17.1 0.0 1.7 2 0 0 2 2 2 1 HEAT repeats CAP_GLY PF01302.20 EDO01669.1 - 2e-11 43.4 1.8 5.4e-11 42.0 1.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain Fib_alpha PF08702.5 EDO01669.1 - 0.091 12.8 9.6 0.099 12.7 0.8 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EDO01669.1 - 0.19 11.4 17.1 0.46 10.2 3.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-CCHC_2 PF13696.1 EDO01669.1 - 0.4 10.2 4.1 3.7 7.1 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDO01669.1 - 0.52 10.0 6.9 2.8 7.6 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Spc7 PF08317.6 EDO01669.1 - 2.6 6.6 21.1 0.39 9.3 3.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DivIVA PF05103.8 EDO01669.1 - 2.7 8.0 21.3 0.47 10.4 3.2 3.3 3 0 0 3 3 3 0 DivIVA protein Med4 PF10018.4 EDO01669.1 - 2.9 7.2 17.8 0.9 8.9 0.7 3.8 4 0 0 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 NmrA PF05368.8 EDO01670.1 - 2.5e-21 76.0 0.0 3.4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDO01670.1 - 8e-14 52.0 0.0 1.4e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EDO01670.1 - 4e-10 39.2 0.1 7.1e-10 38.4 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase DapB_N PF01113.15 EDO01670.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 EDO01670.1 - 1.5e-05 25.0 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EDO01670.1 - 2.6e-05 23.0 0.1 0.00015 20.5 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EDO01670.1 - 2.8e-05 24.0 0.2 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EDO01670.1 - 0.00025 20.5 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EDO01670.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDO01670.1 - 0.013 15.9 0.1 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Med25_VWA PF11265.3 EDO01670.1 - 0.02 13.9 0.1 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Polysacc_synt_2 PF02719.10 EDO01670.1 - 0.025 13.4 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EDO01670.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EDO01670.1 - 0.08 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 EDO01670.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase UQ_con PF00179.21 EDO01671.1 - 2.5e-20 72.3 1.4 2.7e-20 72.2 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme ELFV_dehydrog PF00208.16 EDO01671.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyco_hydro_38 PF01074.17 EDO01673.1 - 3.5e-92 308.5 1.9 5.7e-92 307.8 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EDO01673.1 - 1.4e-70 238.3 0.1 2.4e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EDO01673.1 - 1.3e-26 92.6 0.0 4.5e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Peptidase_A17 PF05380.8 EDO01673.1 - 0.053 13.3 0.1 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Pao retrotransposon peptidase MFS_1 PF07690.11 EDO01674.1 - 5.5e-30 104.2 24.1 5.5e-30 104.2 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EDO01674.1 - 0.0019 16.3 0.6 0.0028 15.8 0.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector zf-B_box PF00643.19 EDO01675.1 - 0.41 10.5 11.6 0.74 9.7 6.2 2.3 1 1 1 2 2 2 0 B-box zinc finger UFD1 PF03152.9 EDO01676.1 - 3.8e-26 91.3 0.0 5.1e-21 74.6 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 DUF1237 PF06824.6 EDO01677.1 - 7.6e-179 594.7 0.1 8.8e-179 594.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PRA1 PF03208.14 EDO01678.1 - 3.2e-34 117.4 1.6 4.7e-34 116.9 1.1 1.2 1 0 0 1 1 1 1 PRA1 family protein TEBP_beta PF07404.6 EDO01678.1 - 0.13 11.3 5.3 0.23 10.5 3.7 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DnaJ PF00226.26 EDO01679.1 - 5.3e-10 38.8 1.7 9.5e-09 34.8 0.4 2.5 2 0 0 2 2 2 2 DnaJ domain DUF2390 PF09523.5 EDO01680.1 - 0.0007 19.7 0.4 2.9 8.1 0.0 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF2390) Ribosomal_L50 PF10501.4 EDO01682.1 - 3.3e-26 91.4 0.0 7.1e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Iso_dh PF00180.15 EDO01685.1 - 4.5e-84 282.3 0.0 5.7e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EDO01686.1 - 6.1e-17 61.8 5.6 1.1e-16 61.0 3.9 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EDO01686.1 - 1.5e-10 41.4 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO01686.1 - 1.5e-06 28.4 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO01686.1 - 1.9e-05 24.3 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO01686.1 - 5.7e-05 22.9 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO01686.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EDO01686.1 - 0.0002 21.7 0.0 0.0008 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO01686.1 - 0.00042 20.8 0.0 0.00075 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO01686.1 - 0.0029 16.7 0.0 0.012 14.6 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EDO01686.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO01686.1 - 0.0089 15.1 0.2 0.058 12.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF3724 PF12521.3 EDO01686.1 - 0.058 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Erv26 PF04148.8 EDO01687.1 - 2.9e-77 258.7 0.3 3.3e-77 258.6 0.2 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 V_ATPase_I PF01496.14 EDO01688.1 - 0.026 12.3 2.1 0.027 12.3 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.1 EDO01688.1 - 0.03 13.9 2.7 0.036 13.6 1.9 1.1 1 0 0 1 1 1 0 AAA domain CMV_1a PF12467.3 EDO01688.1 - 0.031 14.6 1.3 0.038 14.3 0.9 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF2489 PF10675.4 EDO01688.1 - 0.074 12.7 5.9 0.52 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Caudo_TAP PF02413.12 EDO01688.1 - 0.49 10.5 5.0 0.64 10.1 3.4 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein G-patch PF01585.18 EDO01689.1 - 1e-07 31.6 0.1 8.3e-07 28.6 0.1 2.5 1 1 0 1 1 1 1 G-patch domain SGT1 PF07093.6 EDO01689.1 - 0.0099 14.3 28.2 0.013 13.9 19.5 1.2 1 0 0 1 1 1 1 SGT1 protein MIP-T3 PF10243.4 EDO01689.1 - 0.12 10.7 75.8 0.18 10.2 52.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 EDO01689.1 - 1.3 7.5 44.4 2.2 6.8 30.8 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PLRV_ORF5 PF01690.12 EDO01689.1 - 1.5 7.8 35.8 2 7.4 24.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF936 PF06075.7 EDO01689.1 - 5.8 5.7 41.8 8.1 5.2 28.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) V_ATPase_I PF01496.14 EDO01692.1 - 0.00043 18.3 11.2 0.00055 17.9 7.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EDO01692.1 - 0.0018 18.0 18.9 0.19 11.4 0.7 2.8 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein SpoVIF PF14069.1 EDO01692.1 - 0.004 16.8 2.9 0.072 12.8 0.1 3.2 1 1 2 3 3 3 1 Stage VI sporulation protein F HTH_Tnp_Tc3_2 PF01498.13 EDO01692.1 - 0.012 15.6 2.1 1.2 9.2 0.1 3.1 1 1 2 3 3 3 0 Transposase DUF3972 PF13118.1 EDO01692.1 - 0.034 14.2 1.2 0.034 14.2 0.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) DUF904 PF06005.7 EDO01692.1 - 0.036 14.3 5.1 0.036 14.3 3.5 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Desmo_N PF06771.6 EDO01692.1 - 0.036 13.9 4.1 6.4 6.7 0.1 3.1 1 1 0 2 2 2 0 Viral Desmoplakin N-terminus DUF3296 PF11726.3 EDO01692.1 - 0.04 13.4 4.9 0.16 11.5 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3296) Sec8_exocyst PF04048.9 EDO01692.1 - 0.04 13.5 7.7 0.068 12.7 5.2 1.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain CAF-1_p150 PF11600.3 EDO01692.1 - 0.057 12.7 10.1 0.089 12.1 7.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Phage_Mu_Gam PF07352.7 EDO01692.1 - 0.25 10.8 10.9 0.044 13.2 1.0 2.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Pox_A_type_inc PF04508.7 EDO01692.1 - 0.32 10.8 4.4 2.1 8.3 0.3 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Hydantoinase_A PF01968.13 EDO01692.1 - 0.35 9.9 1.7 0.49 9.4 1.2 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase APG6 PF04111.7 EDO01692.1 - 0.49 9.3 14.6 0.67 8.9 10.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Adeno_E3_15_3 PF03307.9 EDO01692.1 - 0.55 9.9 5.2 4.9 6.9 0.1 3.1 2 1 1 3 3 3 0 Adenovirus 15.3kD protein in E3 region DMPK_coil PF08826.5 EDO01692.1 - 2.2 8.2 16.0 2.7 7.9 3.8 3.5 2 1 2 4 4 4 0 DMPK coiled coil domain like Phage_GP20 PF06810.6 EDO01692.1 - 2.9 7.3 11.2 5.9 6.3 0.3 2.3 1 1 0 2 2 2 0 Phage minor structural protein GP20 Lumazine_bd PF12870.2 EDO01692.1 - 5 7.2 8.7 2.1 8.4 1.1 2.3 2 0 0 2 2 2 0 Lumazine-binding domain DUF4200 PF13863.1 EDO01692.1 - 5 7.0 21.6 6.6 6.6 4.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3810 PF12725.2 EDO01692.1 - 5.6 5.7 7.3 0.79 8.5 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Atg14 PF10186.4 EDO01692.1 - 6 5.7 16.3 20 4.0 11.3 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1192 PF06698.6 EDO01692.1 - 7.2 6.5 7.0 12 5.7 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Mem_trans PF03547.13 EDO01693.1 - 6.9e-20 70.6 0.3 9e-20 70.3 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF4501 PF14946.1 EDO01696.1 - 0.08 12.4 0.5 0.11 12.0 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4501) zf-C2H2_4 PF13894.1 EDO01697.1 - 3.5e-11 42.6 47.6 0.039 14.2 0.5 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO01697.1 - 4.6e-09 36.0 57.7 0.016 15.5 0.5 7.8 7 1 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDO01697.1 - 0.0049 16.9 1.1 0.0049 16.9 0.8 6.1 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EDO01697.1 - 0.17 12.2 53.8 0.2 11.9 1.8 7.6 8 0 0 8 8 8 0 Zinc-finger double domain zf-met PF12874.2 EDO01697.1 - 0.18 12.0 0.3 0.18 12.0 0.2 6.2 7 1 0 7 7 7 0 Zinc-finger of C2H2 type GAGA PF09237.6 EDO01697.1 - 2.1 7.9 7.9 1 9.0 0.2 3.1 3 1 1 4 4 4 0 GAGA factor OTU PF02338.14 EDO01699.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Glyco_hydro_28 PF00295.12 EDO01702.1 - 8.2e-97 324.0 21.2 1e-96 323.7 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 AcetylCoA_hyd_C PF13336.1 EDO01702.1 - 0.61 9.7 6.2 0.42 10.2 0.9 2.9 2 1 1 3 3 3 0 Acetyl-CoA hydrolase/transferase C-terminal domain Rif1_N PF12231.3 EDO01704.1 - 2.5e-125 418.3 9.2 4.3e-125 417.5 6.4 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal SNAPc19 PF15497.1 EDO01704.1 - 0.12 12.5 3.0 0.48 10.6 2.1 2.0 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Aldose_epim PF01263.15 EDO01705.1 - 3.3e-35 121.6 0.0 4.1e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAGK_cat PF00781.19 EDO01708.1 - 2.1e-09 36.8 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PRANC PF09372.5 EDO01709.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PRANC domain DUF604 PF04646.7 EDO01711.1 - 0.00059 19.1 0.4 0.0013 18.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EDO01711.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Fringe-like LAGLIDADG_3 PF14528.1 EDO01711.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 LAGLIDADG-like domain Myosin_tail_1 PF01576.14 EDO01712.1 - 9e-05 20.4 8.6 0.0001 20.2 5.9 1.0 1 0 0 1 1 1 1 Myosin tail Macoilin PF09726.4 EDO01712.1 - 0.00046 18.6 5.6 0.00054 18.3 3.9 1.0 1 0 0 1 1 1 1 Transmembrane protein HALZ PF02183.13 EDO01712.1 - 0.0045 16.6 1.4 0.53 10.0 0.1 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 EDO01712.1 - 0.0086 16.4 2.0 0.055 13.8 0.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EDO01712.1 - 0.019 14.6 4.8 0.39 10.4 1.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BBS2_C PF14782.1 EDO01712.1 - 0.039 12.5 0.7 0.045 12.3 0.5 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal GAS PF13851.1 EDO01712.1 - 0.076 12.1 7.7 0.074 12.2 4.4 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 EDO01712.1 - 0.086 11.2 2.7 0.093 11.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 EDO01712.1 - 0.11 12.5 8.2 0.27 11.2 5.2 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC155 PF14662.1 EDO01712.1 - 0.12 11.9 8.4 0.41 10.2 5.8 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CortBP2 PF09727.4 EDO01712.1 - 0.14 11.6 6.5 0.23 10.9 0.2 2.1 1 1 1 2 2 2 0 Cortactin-binding protein-2 Troponin PF00992.15 EDO01712.1 - 0.14 12.1 7.1 0.15 12.0 4.5 1.4 1 1 0 1 1 1 0 Troponin IncA PF04156.9 EDO01712.1 - 0.16 11.5 9.9 0.21 11.1 6.8 1.2 1 0 0 1 1 1 0 IncA protein Spectrin PF00435.16 EDO01712.1 - 0.19 12.0 4.7 6.6 7.0 0.2 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF904 PF06005.7 EDO01712.1 - 0.23 11.7 12.0 0.87 9.9 1.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 EDO01712.1 - 0.25 10.7 6.9 1.4 8.2 3.5 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_Maf PF03131.12 EDO01712.1 - 0.37 11.1 8.5 0.83 9.9 2.2 2.5 1 1 2 3 3 3 0 bZIP Maf transcription factor Zein-binding PF04576.10 EDO01712.1 - 0.5 10.5 5.4 0.17 11.9 0.8 2.1 1 1 1 2 2 2 0 Zein-binding TMF_DNA_bd PF12329.3 EDO01712.1 - 0.59 9.9 13.9 1.9 8.3 6.0 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 EDO01712.1 - 0.63 10.8 3.9 5 7.9 1.9 2.0 1 1 1 2 2 2 0 Occludin homology domain DegS PF05384.6 EDO01712.1 - 0.75 8.9 5.9 2.7 7.1 4.1 1.9 1 1 0 1 1 1 0 Sensor protein DegS APG6 PF04111.7 EDO01712.1 - 1.1 8.2 8.4 1.8 7.5 5.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 EDO01712.1 - 1.2 9.1 6.5 1.2 9.2 0.7 2.5 1 1 2 3 3 3 0 DivIVA protein Rootletin PF15035.1 EDO01712.1 - 1.3 9.0 8.8 2.5 8.0 6.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 EDO01712.1 - 1.8 8.1 11.2 0.44 10.0 1.7 3.1 1 1 1 3 3 3 0 Septum formation initiator Val_tRNA-synt_C PF10458.4 EDO01712.1 - 3.4 7.8 6.4 2.4 8.2 0.1 3.3 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Mnd1 PF03962.10 EDO01712.1 - 3.5 7.2 7.8 5.8 6.5 5.4 1.4 1 1 0 1 1 1 0 Mnd1 family bZIP_1 PF00170.16 EDO01712.1 - 5.7 6.9 8.2 2.5 8.0 0.6 3.0 1 1 1 2 2 2 0 bZIP transcription factor Fez1 PF06818.10 EDO01713.1 - 0.0017 18.4 3.8 0.0023 17.9 2.6 1.1 1 0 0 1 1 1 1 Fez1 IncA PF04156.9 EDO01713.1 - 0.052 13.1 6.3 0.063 12.8 4.3 1.1 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EDO01713.1 - 0.069 13.0 1.3 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_23 PF13476.1 EDO01713.1 - 0.091 13.0 4.7 0.11 12.7 3.3 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 EDO01713.1 - 0.12 12.7 2.4 0.46 10.8 0.2 2.3 2 0 0 2 2 2 0 SlyX RTBV_P46 PF06216.6 EDO01713.1 - 0.12 11.1 1.3 0.45 9.3 0.8 1.8 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein CENP-F_leu_zip PF10473.4 EDO01713.1 - 0.15 11.9 9.8 0.22 11.4 6.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 EDO01713.1 - 0.43 10.7 4.2 0.88 9.6 0.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.11 EDO01713.1 - 0.47 10.7 3.8 0.77 10.0 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF342 PF03961.8 EDO01713.1 - 0.48 8.7 4.0 0.59 8.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Uds1 PF15456.1 EDO01713.1 - 0.87 9.5 6.1 2 8.4 4.3 1.5 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.15 EDO01713.1 - 0.88 9.3 10.1 1.1 9.0 1.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF3987 PF13148.1 EDO01713.1 - 0.95 7.9 6.4 1.4 7.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Viral_P18 PF04521.8 EDO01713.1 - 2.3 7.7 7.4 3.3 7.1 0.7 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein bZIP_2 PF07716.10 EDO01713.1 - 2.7 7.8 8.7 0.14 12.0 1.5 2.1 2 1 1 3 3 3 0 Basic region leucine zipper DivIC PF04977.10 EDO01713.1 - 5.6 6.5 11.5 2.2 7.8 1.4 2.4 1 1 0 2 2 2 0 Septum formation initiator DUF3373 PF11853.3 EDO01713.1 - 6.8 5.1 8.1 30 2.9 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Filament PF00038.16 EDO01714.1 - 3.2e-05 23.5 14.6 0.013 15.0 1.8 2.3 1 1 0 2 2 2 2 Intermediate filament protein Geminin PF07412.7 EDO01714.1 - 0.00013 21.6 10.3 0.0092 15.6 1.3 2.5 2 1 0 2 2 2 2 Geminin AAA_13 PF13166.1 EDO01714.1 - 0.0015 17.1 16.5 0.0018 16.8 11.4 1.1 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.1 EDO01714.1 - 0.0036 16.7 9.2 0.28 10.6 2.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) GAS PF13851.1 EDO01714.1 - 0.0094 15.1 17.9 0.092 11.9 12.5 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EDO01714.1 - 0.018 14.6 6.5 0.018 14.6 4.5 2.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2570 PF10828.3 EDO01714.1 - 0.019 14.5 1.8 0.019 14.5 1.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2570) DUF972 PF06156.8 EDO01714.1 - 0.023 15.0 12.6 0.071 13.4 1.8 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Prp19 PF08606.6 EDO01714.1 - 0.029 14.0 2.4 2.6 7.8 0.2 2.8 2 0 0 2 2 2 0 Prp19/Pso4-like CENP-Q PF13094.1 EDO01714.1 - 0.03 14.3 15.1 0.055 13.4 3.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EDO01714.1 - 0.03 14.2 4.6 0.03 14.2 3.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EDO01714.1 - 0.048 13.1 17.5 0.04 13.4 1.6 3.4 3 1 0 3 3 3 0 Septum formation initiator TMF_TATA_bd PF12325.3 EDO01714.1 - 0.054 13.2 15.8 0.44 10.2 1.2 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EDO01714.1 - 0.066 13.1 18.6 0.2 11.6 3.1 3.8 3 1 1 4 4 4 0 bZIP transcription factor DUF948 PF06103.6 EDO01714.1 - 0.069 13.0 7.0 0.59 10.0 0.4 3.1 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EDO01714.1 - 0.083 12.6 9.1 0.03 14.1 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HSP70 PF00012.15 EDO01714.1 - 0.09 10.6 9.8 0.12 10.2 6.8 1.2 1 0 0 1 1 1 0 Hsp70 protein HALZ PF02183.13 EDO01714.1 - 0.1 12.2 17.1 0.22 11.2 0.6 3.7 4 0 0 4 4 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EDO01714.1 - 0.11 12.1 4.4 4.1 7.1 0.1 2.8 3 0 0 3 3 2 0 Sperm tail C-terminal domain Baculo_PEP_C PF04513.7 EDO01714.1 - 0.12 12.2 4.0 0.23 11.2 0.7 2.5 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 EDO01714.1 - 0.12 12.1 15.9 0.15 11.9 3.1 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.4 EDO01714.1 - 0.16 10.9 16.8 3.4 6.5 10.9 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Myosin_tail_1 PF01576.14 EDO01714.1 - 0.16 9.6 21.0 0.31 8.7 14.5 1.4 1 1 0 1 1 1 0 Myosin tail DUF2681 PF10883.3 EDO01714.1 - 0.17 12.0 12.7 0.73 10.0 2.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) FlaC_arch PF05377.6 EDO01714.1 - 0.23 11.3 6.8 0.69 9.8 0.7 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 EDO01714.1 - 0.25 10.9 18.1 0.31 10.5 5.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 SYCE1 PF15233.1 EDO01714.1 - 0.3 10.9 16.8 0.97 9.3 3.6 2.8 2 1 1 3 3 2 0 Synaptonemal complex central element protein 1 PhoU PF01895.14 EDO01714.1 - 0.33 11.4 7.6 1.1 9.7 1.2 2.7 2 1 0 2 2 2 0 PhoU domain Uso1_p115_C PF04871.8 EDO01714.1 - 0.5 10.3 15.7 2.3 8.1 3.5 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bap31 PF05529.7 EDO01714.1 - 0.66 9.4 16.7 1.8e+02 1.4 11.6 2.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF465 PF04325.8 EDO01714.1 - 0.66 9.7 19.6 1.7 8.4 3.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF465) APG6 PF04111.7 EDO01714.1 - 0.73 8.8 18.6 1.3 7.9 5.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 EDO01714.1 - 0.77 8.3 19.7 0.3 9.7 6.2 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EDO01714.1 - 0.8 9.5 17.9 1.2 8.9 5.5 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cortex-I_coil PF09304.5 EDO01714.1 - 0.83 9.7 17.2 0.11 12.5 4.6 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 EDO01714.1 - 1.1 8.8 17.0 1.2 8.6 5.8 2.2 1 1 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EDO01714.1 - 1.2 9.6 9.8 8.8 6.8 0.4 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 EDO01714.1 - 1.2 9.1 8.9 18 5.3 0.3 3.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DivIVA PF05103.8 EDO01714.1 - 1.3 9.1 19.9 0.87 9.6 1.2 3.2 1 1 3 4 4 3 0 DivIVA protein Mto2_bdg PF12808.2 EDO01714.1 - 1.3 9.1 7.0 7.2 6.8 0.3 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2481 PF10654.4 EDO01714.1 - 1.4 8.6 6.7 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) CENP-F_leu_zip PF10473.4 EDO01714.1 - 1.5 8.7 18.0 0.049 13.4 4.0 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 EDO01714.1 - 1.5 9.2 9.0 0.38 11.0 1.2 3.2 3 1 0 3 3 2 0 Snapin/Pallidin Rho_Binding PF08912.6 EDO01714.1 - 1.6 9.1 18.0 1.7 9.0 1.0 2.8 3 0 0 3 3 2 0 Rho Binding Lge1 PF11488.3 EDO01714.1 - 1.6 8.9 8.1 2.9 8.1 2.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF904 PF06005.7 EDO01714.1 - 1.6 9.0 23.1 2.3 8.5 3.8 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF904) DUF3847 PF12958.2 EDO01714.1 - 1.8 8.3 14.6 0.57 9.9 2.5 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3847) NPV_P10 PF05531.7 EDO01714.1 - 2.2 8.5 6.2 1.5 9.1 1.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EDO01714.1 - 2.2 8.1 7.8 1.7 8.4 0.6 3.1 3 1 1 4 4 3 0 Lipoprotein leucine-zipper DUF641 PF04859.7 EDO01714.1 - 2.3 7.9 12.0 2.5 7.8 0.5 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 EDO01714.1 - 2.5 8.5 7.4 5.7 7.3 0.9 3.1 3 1 1 4 4 2 0 SlyX TPR_MLP1_2 PF07926.7 EDO01714.1 - 2.8 7.6 18.0 4.6 6.9 0.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein KLRAQ PF10205.4 EDO01714.1 - 3.4 7.7 10.2 0.48 10.4 2.1 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3972 PF13118.1 EDO01714.1 - 3.8 7.5 13.5 12 6.0 3.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) Syntaxin-6_N PF09177.6 EDO01714.1 - 4.1 7.8 10.0 0.34 11.3 1.8 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EDO01714.1 - 5.9 6.9 22.9 1.6 8.7 5.7 3.2 1 1 2 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Val_tRNA-synt_C PF10458.4 EDO01714.1 - 7.4 6.7 16.4 0.83 9.7 3.1 3.3 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF4200 PF13863.1 EDO01714.1 - 7.8 6.4 25.2 7.3 6.5 8.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.6 EDO01714.1 - 8.9 6.0 16.3 7.2 6.3 3.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.4 EDO01714.1 - 9 6.0 20.2 5.9 6.6 4.7 2.4 1 1 0 2 2 2 0 Axonemal dynein light chain AKNA PF12443.3 EDO01714.1 - 9.8 6.2 14.4 19 5.3 2.5 3.1 1 1 2 3 3 3 0 AT-hook-containing transcription factor YscJ_FliF_C PF08345.6 EDO01715.1 - 0.018 15.0 8.2 0.028 14.3 5.7 1.4 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Presenilin PF01080.12 EDO01715.1 - 7.8 5.2 7.8 10 4.8 5.4 1.2 1 0 0 1 1 1 0 Presenilin TFIIB PF00382.14 EDO01716.1 - 6e-05 22.7 0.1 0.0002 21.0 0.0 1.9 1 1 0 1 1 1 1 Transcription factor TFIIB repeat Myosin_tail_1 PF01576.14 EDO01717.1 - 0.003 15.3 16.6 0.013 13.3 3.0 2.1 2 0 0 2 2 2 2 Myosin tail RmuC PF02646.11 EDO01717.1 - 0.0087 14.9 6.8 0.034 12.9 0.6 2.2 2 0 0 2 2 2 1 RmuC family DUF972 PF06156.8 EDO01717.1 - 0.0092 16.3 1.4 0.0092 16.3 0.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF972) MscS_porin PF12795.2 EDO01717.1 - 0.017 14.4 13.9 0.14 11.4 2.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain LOH1CR12 PF10158.4 EDO01717.1 - 0.038 13.7 4.5 13 5.5 0.1 3.2 3 0 0 3 3 3 0 Tumour suppressor protein EzrA PF06160.7 EDO01717.1 - 0.12 10.5 5.5 1.7 6.7 0.2 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF3584 PF12128.3 EDO01717.1 - 0.2 8.9 12.6 0.13 9.5 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EDO01717.1 - 0.22 11.2 5.0 0.76 9.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.11 EDO01717.1 - 0.34 10.9 10.6 0.22 11.5 1.7 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Mnd1 PF03962.10 EDO01717.1 - 0.5 10.0 11.2 2.5 7.7 2.1 2.2 2 0 0 2 2 2 0 Mnd1 family Tropomyosin_1 PF12718.2 EDO01717.1 - 0.54 10.1 12.4 1.2 9.0 1.6 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF2570 PF10828.3 EDO01717.1 - 0.73 9.4 7.8 0.069 12.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_MLP1_2 PF07926.7 EDO01717.1 - 0.75 9.5 11.7 0.43 10.3 1.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 EDO01717.1 - 0.77 8.1 10.4 1.6 7.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Hrs_helical PF12210.3 EDO01717.1 - 0.97 9.7 6.5 0.13 12.4 1.1 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Spc24 PF08286.6 EDO01717.1 - 0.98 9.1 9.8 0.5 10.0 0.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 EDO01717.1 - 1 8.8 8.8 1.3 8.5 0.6 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med21 PF11221.3 EDO01717.1 - 1.6 8.6 8.5 0.12 12.3 0.5 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF4446 PF14584.1 EDO01717.1 - 1.9 8.2 7.1 12 5.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DivIC PF04977.10 EDO01717.1 - 2.5 7.6 9.3 0.21 11.1 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator OmpH PF03938.9 EDO01717.1 - 4.4 7.2 9.4 6.5 6.6 1.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EDO01717.1 - 7.7 4.8 6.7 2.2 6.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Prefoldin PF02996.12 EDO01717.1 - 8.3 6.0 10.4 2.8 7.6 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit Cu-oxidase_3 PF07732.10 EDO01721.1 - 4.3e-44 149.0 8.9 5e-43 145.5 0.3 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EDO01721.1 - 5.8e-37 127.0 0.3 1.1e-33 116.3 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDO01721.1 - 1e-33 115.7 12.3 1.3e-30 105.6 2.5 4.0 4 0 0 4 4 4 3 Multicopper oxidase Connexin PF00029.14 EDO01721.1 - 0.04 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Connexin Tom37 PF10568.4 EDO01722.1 - 0.13 12.4 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Kdo PF06293.9 EDO01724.1 - 5.3e-05 22.3 0.0 0.00015 20.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDO01724.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDO01724.1 - 0.0013 18.4 1.2 0.0044 16.7 0.8 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EDO01724.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Glyco_hydro_92 PF07971.7 EDO01725.1 - 9.7e-150 499.5 5.5 1.2e-149 499.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ABC_membrane PF00664.18 EDO01727.1 - 1.4e-78 264.0 34.1 1.2e-42 146.1 8.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO01727.1 - 1.1e-59 200.5 0.0 8.5e-30 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO01727.1 - 5.8e-14 51.8 7.7 1.3e-07 31.0 0.5 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO01727.1 - 9.3e-10 37.8 3.8 0.00016 21.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO01727.1 - 7.9e-09 35.7 0.1 0.0015 18.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDO01727.1 - 9e-09 35.5 0.0 0.00041 20.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EDO01727.1 - 1.2e-08 35.2 0.1 0.083 12.8 0.1 4.5 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EDO01727.1 - 6e-08 32.0 0.0 0.0033 16.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDO01727.1 - 7.6e-07 28.7 2.0 0.69 9.2 0.3 3.6 3 0 0 3 3 3 3 AAA domain AAA_17 PF13207.1 EDO01727.1 - 1.1e-06 29.4 0.7 0.083 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDO01727.1 - 1e-05 24.3 4.9 0.027 13.0 0.0 3.6 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_33 PF13671.1 EDO01727.1 - 5.9e-05 22.9 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDO01727.1 - 0.00021 21.6 1.5 0.25 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EDO01727.1 - 0.00022 20.7 8.6 0.082 12.3 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain DEAD PF00270.24 EDO01727.1 - 0.00061 19.3 0.1 0.42 10.0 0.0 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase MobB PF03205.9 EDO01727.1 - 0.0016 18.1 3.6 3.2 7.4 0.1 3.5 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EDO01727.1 - 0.0031 17.4 0.7 1.1 9.1 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EDO01727.1 - 0.0042 17.0 1.5 1.1 9.2 0.5 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EDO01727.1 - 0.0092 15.7 0.1 5.7 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 EDO01727.1 - 0.012 14.1 0.1 2.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 EDO01727.1 - 0.014 15.7 3.2 0.51 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDO01727.1 - 0.015 14.4 0.2 1 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CRT-like PF08627.5 EDO01727.1 - 0.015 15.2 0.1 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 CRT-like APS_kinase PF01583.15 EDO01727.1 - 0.02 14.5 1.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EDO01727.1 - 0.026 14.7 0.5 16 5.7 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.16 EDO01727.1 - 0.035 13.2 0.8 0.49 9.5 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDO01727.1 - 0.036 13.5 1.4 8.3 5.7 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 EDO01727.1 - 0.036 13.7 2.6 3.5 7.2 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EDO01727.1 - 0.038 13.7 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDO01727.1 - 0.042 13.3 0.1 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EDO01727.1 - 0.044 12.6 0.1 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 EDO01727.1 - 0.11 12.7 1.1 20 5.4 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EDO01727.1 - 0.11 10.9 0.6 0.24 9.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDO01727.1 - 0.28 10.9 4.1 14 5.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 gag_pre-integrs PF13976.1 EDO01728.1 - 0.14 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 GAG-pre-integrase domain Ceramidase_alk PF04734.8 EDO01729.1 - 1.7e-245 816.0 0.0 2e-245 815.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF383 PF04063.9 EDO01730.1 - 7.3e-75 250.7 1.1 3.2e-74 248.6 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EDO01730.1 - 1.6e-23 81.9 3.7 2.7e-23 81.2 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Glyco_hydro_43 PF04616.9 EDO01731.1 - 2.6e-65 220.3 0.4 3.6e-65 219.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_28 PF00295.12 EDO01732.1 - 1.8e-42 145.4 17.9 1e-41 142.9 12.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 RL11D PF11088.3 EDO01732.1 - 4.8 7.0 8.9 0.17 11.6 0.3 2.7 2 2 1 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Sugar_tr PF00083.19 EDO01733.1 - 2.8e-96 322.8 26.1 3.4e-96 322.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO01733.1 - 2.1e-29 102.3 47.7 9.4e-29 100.2 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EDO01733.1 - 0.67 8.6 12.4 0.05 12.3 4.2 2.1 2 1 1 3 3 3 0 PUCC protein PAP_assoc PF03828.14 EDO01734.1 - 2.1e-14 53.2 0.0 2.6e-13 49.7 0.0 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDO01734.1 - 0.0032 17.7 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain WASH-7_mid PF14744.1 EDO01734.1 - 0.032 13.0 0.3 0.05 12.4 0.2 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 TFIIF_alpha PF05793.7 EDO01736.1 - 7.3e-06 24.6 59.7 7.3e-06 24.6 41.4 4.8 1 1 1 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 EDO01737.1 - 3.1e-42 144.2 8.2 3.1e-42 144.2 5.7 2.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex CPSase_sm_chain PF00988.17 EDO01739.1 - 3.2e-46 156.0 0.0 5.7e-46 155.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EDO01739.1 - 1.3e-45 155.2 0.0 1.8e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO01739.1 - 2.9e-06 26.8 0.1 0.00023 20.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EDO01739.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family SAP PF02037.22 EDO01740.1 - 8.2e-13 47.5 0.3 1.4e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 SAP domain ETF PF01012.16 EDO01742.1 - 1.6e-34 119.0 0.2 2.1e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SH3_1 PF00018.23 EDO01742.1 - 0.071 12.5 0.1 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain NUDIX PF00293.23 EDO01743.1 - 1.4e-13 50.6 0.0 2.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF1771 PF08590.5 EDO01744.1 - 3e-13 49.5 10.3 3e-13 49.5 7.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EDO01744.1 - 3e-10 40.1 0.0 2e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 EDO01744.1 - 4.2e-07 29.5 0.7 0.0046 16.6 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNARE_assoc PF09335.6 EDO01746.1 - 1.9e-13 50.7 3.2 1.9e-13 50.7 2.3 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein F-box-like PF12937.2 EDO01748.1 - 0.0065 16.1 0.1 0.016 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 EDO01748.1 - 0.088 12.4 0.0 0.32 10.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Plasmid_stab_B PF10784.4 EDO01749.1 - 0.062 12.9 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Plasmid stability protein Cys_Met_Meta_PP PF01053.15 EDO01750.1 - 4.2e-56 189.8 0.0 9.3e-56 188.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDO01750.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SapB_1 PF05184.10 EDO01750.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 HATPase_c_3 PF13589.1 EDO01751.1 - 2.3e-14 53.1 0.0 5.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO01751.1 - 2e-11 43.5 0.1 5.2e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EDO01751.1 - 4.5e-09 35.7 0.0 9.1e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain tRNA-synt_1 PF00133.17 EDO01752.1 - 9.3e-185 615.0 2.4 7.5e-141 470.0 0.1 3.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO01752.1 - 3.6e-32 111.2 0.2 3.6e-32 111.2 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDO01752.1 - 4.1e-14 52.0 0.0 0.0013 17.4 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDO01752.1 - 1.5e-10 40.7 8.9 9e-09 34.8 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EDO01752.1 - 0.0096 15.9 5.7 0.0096 15.9 4.0 3.1 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm DUF4028 PF13220.1 EDO01752.1 - 0.045 13.3 1.6 0.16 11.6 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) tRNA-synt_1e PF01406.14 EDO01752.1 - 0.045 12.8 0.0 0.045 12.8 0.0 2.8 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain DUF4185 PF13810.1 EDO01753.1 - 0.0017 17.3 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) zf-CCCH PF00642.19 EDO01754.1 - 1.2e-08 34.4 16.6 4.1e-07 29.5 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EDO01754.1 - 5.1e-06 26.2 0.0 8.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO01754.1 - 0.00032 20.2 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO01754.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Oxysterol_BP PF01237.13 EDO01755.1 - 8.6e-87 290.9 0.0 1.2e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein TRP PF06011.7 EDO01756.1 - 9.9e-94 314.3 14.6 6.5e-93 311.6 10.1 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDO01756.1 - 2.6e-32 111.7 0.4 3.8e-32 111.2 0.3 1.2 1 0 0 1 1 1 1 ML-like domain DUF4271 PF14093.1 EDO01756.1 - 0.35 10.5 13.3 0.046 13.3 6.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF4164 PF13747.1 EDO01757.1 - 0.15 12.2 0.6 0.31 11.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) PPV_E2_C PF00511.12 EDO01758.1 - 0.074 13.0 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 E2 (early) protein, C terminal C2 PF00168.25 EDO01759.1 - 3.5e-64 212.6 2.2 8.4e-20 70.4 0.0 5.5 5 0 0 5 5 5 5 C2 domain MFS_1 PF07690.11 EDO01760.1 - 2.1e-15 56.3 20.5 2.1e-15 56.3 14.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sec62 PF03839.11 EDO01760.1 - 0.5 9.7 1.8 3.3 7.0 0.0 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 DUF1049 PF06305.6 EDO01760.1 - 4.4 6.8 11.2 9.5 5.7 1.1 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FolB PF02152.13 EDO01761.1 - 2e-14 53.7 0.0 3.3e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase ING PF12998.2 EDO01762.1 - 2.5e-21 75.8 0.1 3.7e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EDO01762.1 - 6.6e-08 32.1 8.4 1.1e-07 31.4 5.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EDO01762.1 - 0.03 14.4 0.2 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EDO01762.1 - 1.8 8.6 6.2 3.1 7.8 4.3 1.4 1 0 0 1 1 1 0 RING-like domain Hist_deacetyl PF00850.14 EDO01763.1 - 8.5e-81 271.6 0.1 1.4e-80 270.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DUF3605 PF12239.3 EDO01764.1 - 1.5e-62 210.1 2.9 1.5e-62 210.1 1.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3605) Herpes_US9 PF06072.6 EDO01765.1 - 0.082 12.7 0.9 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 UDPGP PF01704.13 EDO01767.1 - 2.4e-184 612.7 0.3 2.8e-184 612.4 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EDO01767.1 - 0.013 14.0 2.4 0.11 10.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) PilO PF04350.8 EDO01767.1 - 0.06 13.2 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO zf-RING_2 PF13639.1 EDO01768.1 - 5.5e-09 35.7 11.6 2.7e-08 33.4 4.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO01768.1 - 0.0007 19.6 11.5 0.0024 17.9 5.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO01768.1 - 0.0029 17.2 4.2 0.0029 17.2 2.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EDO01768.1 - 0.42 10.6 8.7 0.2 11.7 3.6 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.1 EDO01768.1 - 0.68 10.0 15.4 0.098 12.6 4.1 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EDO01768.1 - 0.76 9.7 4.9 2.8 7.9 2.0 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EDO01768.1 - 4 7.2 11.1 25 4.7 4.3 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO01768.1 - 4.6 6.9 8.6 28 4.4 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO01768.1 - 4.8 7.0 9.1 5.5 6.9 4.3 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_clus PF00172.13 EDO01769.1 - 9.2e-05 22.2 9.8 0.00016 21.5 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO01769.1 - 0.00057 18.8 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiS PF02597.15 EDO01770.1 - 8.9e-06 26.0 0.0 2.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 ThiS family RNB PF00773.14 EDO01771.1 - 9.3e-48 163.1 0.0 1.5e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain Acetyltransf_8 PF13523.1 EDO01773.1 - 5.4e-36 123.7 0.2 7.5e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 EDO01774.1 - 1.6e-47 161.7 0.0 2.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1731 PF08338.6 EDO01774.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Condensation PF00668.15 EDO01775.1 - 6.8e-71 238.5 0.0 2.6e-37 128.3 0.0 2.8 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.23 EDO01775.1 - 6.7e-55 186.1 0.0 1.2e-36 126.0 0.0 3.2 2 1 1 3 3 3 3 AMP-binding enzyme PP-binding PF00550.20 EDO01775.1 - 1.4e-28 98.9 0.2 3.3e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDO01775.1 - 0.00012 22.9 0.0 0.26 12.2 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 EDO01777.1 - 3.7e-76 256.1 28.3 1.8e-47 162.0 4.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO01777.1 - 1.9e-58 196.5 0.0 2.2e-31 109.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO01777.1 - 2.2e-13 49.9 6.7 6.2e-06 25.5 0.1 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDO01777.1 - 6e-08 33.5 0.2 0.0044 17.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EDO01777.1 - 2.4e-07 30.1 0.5 0.00056 19.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO01777.1 - 3.2e-07 30.5 3.9 0.0081 16.1 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EDO01777.1 - 3.5e-07 30.4 0.0 0.1 12.5 0.0 3.6 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 EDO01777.1 - 6.2e-07 29.6 0.2 0.67 10.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 EDO01777.1 - 3.6e-06 25.8 0.3 0.0045 15.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 EDO01777.1 - 4.6e-06 26.3 3.0 0.2 11.2 0.0 4.4 4 1 1 5 5 5 2 AAA domain APS_kinase PF01583.15 EDO01777.1 - 5.1e-06 26.2 0.1 0.0045 16.6 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase Zeta_toxin PF06414.7 EDO01777.1 - 1.6e-05 24.0 0.1 0.024 13.7 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 EDO01777.1 - 4e-05 23.2 0.1 0.13 11.9 0.0 3.3 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EDO01777.1 - 9.7e-05 22.6 0.0 0.29 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO01777.1 - 0.00013 21.8 0.0 0.63 9.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EDO01777.1 - 0.0002 21.5 1.1 6.9 6.8 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EDO01777.1 - 0.00046 19.4 0.0 0.0095 15.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDO01777.1 - 0.0012 18.6 1.7 1.9 8.4 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EDO01777.1 - 0.0055 16.4 0.0 2.7 7.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EDO01777.1 - 0.01 15.6 0.6 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EDO01777.1 - 0.017 14.5 7.6 0.41 10.0 0.0 4.4 5 0 0 5 5 5 0 AAA domain AAA_23 PF13476.1 EDO01777.1 - 0.022 15.0 1.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EDO01777.1 - 0.025 13.9 0.0 0.88 8.9 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase DUF3987 PF13148.1 EDO01777.1 - 0.032 12.8 0.1 6.3 5.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) SRP54 PF00448.17 EDO01777.1 - 0.04 13.3 0.0 9.6 5.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EDO01777.1 - 0.37 10.1 2.3 7.6 5.8 0.0 3.1 4 0 0 4 4 4 0 AAA-like domain WD40 PF00400.27 EDO01780.1 - 7e-07 28.8 0.0 8e-06 25.5 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 EDO01780.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Cytochrom_D1 PF02239.11 EDO01780.1 - 0.01 14.1 0.0 2.1 6.5 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain UT PF03253.9 EDO01781.1 - 0.21 10.4 1.9 0.22 10.3 1.3 1.0 1 0 0 1 1 1 0 Urea transporter DUF2079 PF09852.4 EDO01781.1 - 0.91 8.1 3.3 0.99 8.0 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) zf-CCHC PF00098.18 EDO01783.1 - 9.5e-08 31.6 2.6 1.7e-07 30.8 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EDO01783.1 - 0.0023 17.3 6.8 0.0023 17.3 4.7 1.7 1 1 0 1 1 1 1 GAG-polyprotein viral zinc-finger APO_RNA-bind PF05634.6 EDO01783.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding IBR PF01485.16 EDO01783.1 - 0.072 12.9 2.5 0.12 12.2 1.7 1.4 1 0 0 1 1 1 0 IBR domain zf-CCHC_4 PF14392.1 EDO01783.1 - 0.15 11.7 2.0 0.26 10.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.5 EDO01784.1 - 0.084 12.2 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger FliX PF10768.4 EDO01785.1 - 0.074 13.2 3.5 0.11 12.7 1.7 1.7 1 1 1 2 2 2 0 Class II flagellar assembly regulator APG6 PF04111.7 EDO01785.1 - 0.22 10.5 5.5 0.28 10.1 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Zn_clus PF00172.13 EDO01785.1 - 1.6 8.6 10.4 6.8 6.6 1.2 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sel1 PF08238.7 EDO01786.1 - 2.2e-34 117.1 31.2 0.0002 21.8 1.4 8.2 7 1 1 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 EDO01786.1 - 0.041 14.3 6.9 4.8 7.8 0.2 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO01786.1 - 0.43 11.3 17.1 1.3 9.7 1.5 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.10 EDO01788.1 - 4.5e-281 932.8 0.3 7.3e-281 932.1 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO01788.1 - 3e-16 59.7 6.9 1.3e-15 57.5 4.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO01788.1 - 4.4e-14 52.8 0.0 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EDO01788.1 - 9.4e-14 50.9 0.2 4.3e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EDO01788.1 - 0.00022 20.5 0.1 0.0041 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDO01788.1 - 0.0012 18.5 0.0 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF639 PF04842.7 EDO01788.1 - 0.0077 14.4 0.1 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) PAN_1 PF00024.21 EDO01789.1 - 0.012 15.2 20.1 3 7.6 0.2 5.6 5 0 0 5 5 5 0 PAN domain Lustrin_cystein PF14625.1 EDO01791.1 - 5.1 7.2 17.6 2.2 8.4 4.6 2.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Sod_Fe_C PF02777.13 EDO01792.1 - 7.6e-14 51.4 0.1 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Aminotran_5 PF00266.14 EDO01793.1 - 1.5e-10 40.3 0.0 3e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EDO01794.1 - 1.6e-22 79.4 0.0 3.3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EDO01794.1 - 2.8e-16 59.1 0.0 5.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain SHR3_chaperone PF08229.6 EDO01796.1 - 2.5e-82 274.6 0.0 2.9e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 HlyIII PF03006.15 EDO01796.1 - 0.047 13.0 1.9 0.086 12.2 1.3 1.4 1 0 0 1 1 1 0 Haemolysin-III related MFS_1 PF07690.11 EDO01796.1 - 0.31 9.7 5.3 1.3 7.6 4.4 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Polyketide_cyc2 PF10604.4 EDO01797.1 - 0.0028 17.8 0.0 0.0035 17.5 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sugar_tr PF00083.19 EDO01798.1 - 5.4e-83 279.0 25.8 6.1e-83 278.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO01798.1 - 3.5e-30 104.9 27.0 1.2e-29 103.1 17.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDO01798.1 - 1e-08 34.0 19.4 4.1e-05 22.1 2.6 2.9 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3772 PF12607.3 EDO01802.1 - 0.055 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) BTB PF00651.26 EDO01803.1 - 2.5e-05 24.2 0.1 5.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EDO01804.1 - 5.1e-05 23.2 0.0 9.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF771 PF05595.6 EDO01804.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF771) BTB PF00651.26 EDO01805.1 - 5.7e-05 23.0 0.2 0.00015 21.6 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Biliv-reduc_cat PF09166.5 EDO01805.1 - 0.11 12.5 0.1 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Biliverdin reductase, catalytic HrpF PF06266.7 EDO01805.1 - 0.28 11.3 1.9 0.87 9.7 0.2 2.2 2 0 0 2 2 2 0 HrpF protein Peptidase_M20 PF01546.23 EDO01806.1 - 2.3e-22 79.4 0.2 3.3e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO01806.1 - 3.1e-22 78.4 0.1 5.3e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EDO01806.1 - 0.052 13.2 0.2 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 Prenyltrans PF00432.16 EDO01807.1 - 5.1e-36 121.9 4.9 7e-09 35.0 0.0 6.9 6 2 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO01807.1 - 1.2e-21 77.1 0.0 1.4e-12 48.0 0.0 3.8 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDO01807.1 - 0.00049 20.0 0.0 0.031 14.2 0.0 3.1 2 1 1 3 3 3 1 Prenyltransferase-like Ilm1 PF10311.4 EDO01808.1 - 8.7e-58 194.4 0.7 1e-57 194.2 0.5 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 NatB_MDM20 PF09797.4 EDO01809.1 - 6.8e-96 321.1 1.7 1.4e-95 320.1 1.2 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EDO01809.1 - 0.026 14.8 0.5 77 3.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Iron_transport PF10634.4 EDO01809.1 - 0.055 13.3 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Fe2+ transport protein DUF1903 PF08991.5 EDO01810.1 - 8.4e-06 25.8 2.8 1.1e-05 25.4 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EDO01810.1 - 3.2e-05 23.7 2.0 6.9e-05 22.6 1.5 1.6 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EDO01810.1 - 0.049 13.4 2.9 1.3 8.9 0.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EDO01810.1 - 0.11 12.3 4.1 0.27 11.1 2.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 EDO01810.1 - 0.13 12.3 2.7 0.21 11.6 1.8 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 2OG-Fe_Oxy_2 PF10014.4 EDO01811.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe dioxygenase UPF0547 PF10571.4 EDO01812.1 - 0.002 17.7 7.0 0.0022 17.6 1.8 2.7 2 1 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EDO01812.1 - 0.03 13.5 9.9 0.096 11.9 2.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Trm112p PF03966.11 EDO01812.1 - 0.057 13.7 0.1 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Trm112p-like protein Zn-ribbon_8 PF09723.5 EDO01812.1 - 0.1 12.5 6.7 18 5.3 0.4 3.5 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 EDO01812.1 - 0.13 12.1 9.8 0.95 9.3 7.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 EDO01812.1 - 0.26 10.8 8.3 0.05 13.1 0.6 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EDO01812.1 - 1.5 8.4 11.4 11 5.6 4.8 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EDO01812.1 - 2 8.1 7.8 2.6 7.7 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.11 EDO01812.1 - 5.4 6.8 8.1 14 5.5 0.5 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Pkinase PF00069.20 EDO01813.1 - 1.5e-47 161.9 0.0 2.5e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01813.1 - 4.5e-24 84.9 0.0 6.9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO01813.1 - 8e-10 38.1 0.0 1.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO01813.1 - 0.0023 17.0 0.1 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EDO01813.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EDO01813.1 - 0.086 12.5 0.1 0.086 12.5 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO01813.1 - 0.2 11.1 0.0 0.53 9.8 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase KH_1 PF00013.24 EDO01815.1 - 0.00015 21.3 1.6 0.00029 20.4 1.1 1.4 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EDO01816.1 - 2.2e-192 640.0 1.5 2.6e-192 639.7 1.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 EDO01816.1 - 0.042 13.2 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 TraH_2 TauD PF02668.11 EDO01817.1 - 7.4e-42 143.8 0.0 9.1e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EDO01819.1 - 9.5e-19 67.3 15.7 9.5e-19 67.3 10.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2909 PF11137.3 EDO01819.1 - 0.028 14.1 0.4 4.8 6.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF3139 PF11337.3 EDO01819.1 - 0.068 13.4 0.4 0.63 10.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) AAA PF00004.24 EDO01820.1 - 4.8e-10 39.7 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO01820.1 - 0.002 18.1 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EDO01820.1 - 0.0074 16.0 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO01820.1 - 0.029 14.5 0.3 0.099 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO01820.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EDO01820.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3892 PF13031.1 EDO01821.1 - 0.037 14.4 0.2 0.073 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) zf-C2H2 PF00096.21 EDO01822.1 - 0.011 16.0 1.7 0.027 14.8 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO01822.1 - 0.02 15.1 1.0 0.049 13.9 0.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Mur_ligase_M PF08245.7 EDO01823.1 - 0.00013 22.0 0.9 0.0013 18.7 0.6 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EDO01823.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_C PF02875.16 EDO01824.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 EDO01824.1 - 0.047 13.7 0.1 0.52 10.3 0.0 2.5 2 1 0 2 2 2 0 Mur ligase middle domain MFS_1 PF07690.11 EDO01825.1 - 2e-41 141.8 40.5 2.7e-39 134.8 28.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO01825.1 - 2.6e-11 42.4 11.0 3.9e-11 41.8 7.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_18A PF09771.4 EDO01825.1 - 0.11 12.5 0.7 0.51 10.3 0.5 2.1 1 0 0 1 1 1 0 Transmembrane protein 188 SdpI PF13630.1 EDO01827.1 - 0.34 10.6 0.3 0.65 9.7 0.2 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family Homeobox PF00046.24 EDO01828.1 - 9.9e-07 28.2 0.0 4.9e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EDO01828.1 - 0.0033 16.4 0.9 0.01 14.9 0.1 2.0 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez EABR PF12180.3 EDO01828.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 adh_short PF00106.20 EDO01830.1 - 5.9e-20 71.8 0.0 8.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO01830.1 - 3.6e-05 23.6 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDO01830.1 - 4.1e-05 23.1 0.1 7.1e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EDO01830.1 - 0.00056 19.6 0.3 0.0016 18.1 0.2 1.6 1 1 0 1 1 1 1 KR domain ADH_N PF08240.7 EDO01831.1 - 1.6e-19 69.6 0.2 3.2e-19 68.7 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO01831.1 - 4.6e-08 32.6 0.0 9.4e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EDO01831.1 - 0.023 13.1 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EDO01831.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PAPS_reduct PF01507.14 EDO01835.1 - 2.1e-43 148.1 0.4 3.2e-43 147.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family EI24 PF07264.6 EDO01836.1 - 0.016 14.6 11.7 0.31 10.4 8.1 2.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Complex1_LYR_1 PF13232.1 EDO01839.1 - 4.1e-21 74.9 5.2 5.4e-21 74.5 3.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDO01839.1 - 1.2e-19 69.7 4.7 1.7e-19 69.3 3.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EDO01839.1 - 0.0016 18.8 1.8 0.002 18.5 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_5 PF12695.2 EDO01839.1 - 0.071 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Toxin_43 PF15604.1 EDO01839.1 - 0.64 10.0 4.1 0.74 9.8 2.8 1.1 1 0 0 1 1 1 0 Putative toxin 43 ATP-sulfurylase PF01747.12 EDO01840.1 - 2.9e-88 294.7 0.0 4.4e-88 294.1 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EDO01840.1 - 5.5e-55 185.3 0.1 8.5e-55 184.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EDO01840.1 - 2.1e-52 176.7 0.0 3.2e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.7 EDO01840.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EDO01840.1 - 0.053 12.7 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDO01840.1 - 0.094 12.5 0.5 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.17 EDO01841.1 - 9.2e-10 37.8 24.8 1.3e-08 34.1 17.2 2.0 1 1 0 1 1 1 1 Acyltransferase family adh_short PF00106.20 EDO01842.1 - 2.8e-20 72.9 0.1 5.5e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO01842.1 - 5.3e-12 46.0 0.0 7.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EDO01842.1 - 0.00049 19.3 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EDO01842.1 - 0.0071 16.3 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding GARS_C PF02843.11 EDO01842.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Methyltransf_22 PF13383.1 EDO01843.1 - 5.7e-23 81.7 0.0 8.5e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EDO01843.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4578 PF15147.1 EDO01843.1 - 0.34 11.2 2.8 0.83 10.0 0.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4578) Raptor_N PF14538.1 EDO01845.1 - 0.0025 17.6 1.9 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain V_ATPase_I PF01496.14 EDO01845.1 - 0.75 7.5 7.1 1.4 6.7 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EDO01845.1 - 6 6.4 12.3 15 5.1 8.5 1.6 1 0 0 1 1 1 0 IncA protein HAD PF12710.2 EDO01846.1 - 6.3e-18 65.6 0.1 9.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO01846.1 - 9.2e-13 49.0 1.7 1.8e-11 44.8 1.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO01846.1 - 8.2e-09 35.4 0.8 1.5e-07 31.2 0.2 2.6 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO01846.1 - 8.2e-06 26.1 0.0 5.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDO01846.1 - 3.7e-05 22.9 0.0 0.00061 19.0 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 EDO01846.1 - 0.0048 15.9 0.2 0.0073 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acid_PPase PF12689.2 EDO01846.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Acid Phosphatase DEAD PF00270.24 EDO01847.1 - 3.9e-44 150.1 0.0 9.8e-44 148.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO01847.1 - 1e-20 73.3 0.2 2.5e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDO01847.1 - 0.22 9.9 0.0 1.2 7.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Septin PF00735.13 EDO01848.1 - 1.5e-31 109.4 0.0 5.2e-11 42.0 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EDO01848.1 - 0.00089 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EDO01848.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EDO01848.1 - 0.014 14.4 0.0 0.037 13.0 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.1 EDO01848.1 - 0.037 14.0 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EDO01848.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 EDO01848.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SUR7 PF06687.7 EDO01850.1 - 2.4e-30 105.6 14.7 3e-30 105.3 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 EDO01850.1 - 0.061 12.3 4.4 0.098 11.7 3.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein DUF4231 PF14015.1 EDO01850.1 - 0.079 12.9 1.8 0.12 12.3 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Pox_P21 PF05313.7 EDO01850.1 - 0.14 11.4 3.8 0.24 10.6 2.6 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NfeD PF01957.13 EDO01850.1 - 5 7.2 11.1 0.16 12.1 2.1 2.4 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2721 PF11026.3 EDO01850.1 - 5.3 6.6 12.1 0.23 11.0 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ABC1 PF03109.11 EDO01851.1 - 1.3e-11 44.5 0.2 2.9e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EDO01851.1 - 0.0011 18.7 0.2 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDO01851.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TOBE_3 PF12857.2 EDO01854.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 TOBE-like domain Actin PF00022.14 EDO01855.1 - 3e-17 62.1 0.0 2.5e-16 59.0 0.0 2.1 1 1 0 1 1 1 1 Actin SPRY PF00622.23 EDO01857.1 - 1.2e-07 31.8 0.0 7e-07 29.3 0.0 2.2 3 0 0 3 3 3 1 SPRY domain Fungal_trans PF04082.13 EDO01858.1 - 6.1e-12 44.9 0.5 3.4e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tom22 PF04281.8 EDO01858.1 - 0.57 9.7 5.7 1.3 8.5 4.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PAT1 PF09770.4 EDO01858.1 - 7.1 4.7 22.4 10 4.2 15.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2269 PF10027.4 EDO01859.1 - 0.0097 15.6 0.5 0.016 14.9 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) MutS_V PF00488.16 EDO01860.1 - 7.8e-81 270.9 0.0 1.2e-80 270.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO01860.1 - 6.4e-48 163.2 0.0 1.1e-47 162.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO01860.1 - 1.1e-32 112.3 0.0 4.7e-32 110.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EDO01860.1 - 2e-14 53.8 0.1 1.8e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EDO01860.1 - 9.4e-12 44.9 0.8 2.1e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EDO01860.1 - 4.5e-05 23.8 3.0 0.0022 18.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF1564 PF07600.6 EDO01860.1 - 0.00078 18.8 0.3 0.0019 17.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) AAA_29 PF13555.1 EDO01860.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hemagglutinin PF00509.13 EDO01860.1 - 0.064 11.4 0.2 0.11 10.6 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin AAA_21 PF13304.1 EDO01860.1 - 0.083 12.8 0.2 0.083 12.8 0.2 2.7 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 EDO01861.1 - 3.2e-21 75.4 40.2 4e-20 71.8 27.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO01861.1 - 6.4e-09 34.8 12.8 6.4e-09 34.8 8.9 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 EDO01861.1 - 0.0016 16.6 6.2 0.0016 16.6 4.3 2.3 1 1 0 2 2 2 2 Transmembrane secretion effector Sulfatase PF00884.18 EDO01862.1 - 2.1e-38 132.2 0.5 3.7e-38 131.4 0.4 1.3 1 0 0 1 1 1 1 Sulfatase Bac_rhodopsin PF01036.13 EDO01864.1 - 4.6e-60 202.6 16.6 6.3e-60 202.2 11.5 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 EDO01864.1 - 3.3 7.0 15.8 2.5 7.4 1.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Amino_oxidase PF01593.19 EDO01865.1 - 1.4e-17 63.9 0.0 8.1e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDO01865.1 - 5.8e-15 55.0 0.1 1.9e-14 53.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO01865.1 - 6.4e-15 54.9 1.4 1.3e-13 50.6 0.2 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO01865.1 - 4.4e-08 32.3 1.9 9.4e-05 21.4 2.4 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EDO01865.1 - 8.2e-07 27.8 0.5 0.0049 15.3 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EDO01865.1 - 7.3e-05 22.0 0.0 0.00015 20.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO01865.1 - 8.4e-05 22.5 0.0 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO01865.1 - 0.00028 21.2 1.4 0.17 12.2 1.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO01865.1 - 0.00063 18.8 0.3 0.0053 15.8 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDO01865.1 - 0.0011 19.0 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO01865.1 - 0.0019 17.3 0.4 0.0037 16.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EDO01865.1 - 0.003 17.3 0.5 0.11 12.2 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EDO01865.1 - 0.016 13.5 0.0 2.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GIDA PF01134.17 EDO01865.1 - 0.036 12.9 4.0 0.041 12.7 1.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDO01865.1 - 0.064 12.9 1.2 0.13 11.9 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EDO01865.1 - 0.31 9.8 0.9 0.48 9.2 0.3 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein SQS_PSY PF00494.14 EDO01866.1 - 3.6e-63 213.3 0.0 4.2e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EDO01867.1 - 2.8e-138 461.5 0.0 3.3e-138 461.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 EDO01867.1 - 0.041 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor Grp1_Fun34_YaaH PF01184.14 EDO01869.1 - 2.7e-85 284.9 20.3 3.2e-85 284.6 14.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DNA_pol_A_exo1 PF01612.15 EDO01870.1 - 0.027 13.9 0.7 8 5.9 0.0 3.5 4 1 0 4 4 4 0 3'-5' exonuclease zf-C3HC4_3 PF13920.1 EDO01871.1 - 0.12 12.1 8.6 0.41 10.3 4.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C6_DPF PF10170.4 EDO01871.1 - 0.16 12.0 4.0 0.31 11.1 1.9 1.9 2 0 0 2 2 2 0 Cysteine-rich domain zf-C2HC5 PF06221.8 EDO01871.1 - 0.82 9.4 9.1 2.8 7.7 4.7 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.11 EDO01871.1 - 0.94 9.3 4.9 0.32 10.9 1.5 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.16 EDO01871.1 - 2.5 8.0 10.7 9.7 6.1 7.4 2.1 1 1 0 1 1 1 0 FYVE zinc finger Cyclin_N PF00134.18 EDO01872.1 - 1.6e-35 121.4 0.6 1.6e-35 121.4 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO01872.1 - 2.4e-10 40.3 0.2 8.8e-10 38.5 0.2 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain 2OG-Fe_Oxy_2 PF10014.4 EDO01877.1 - 0.071 12.4 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase Abhydrolase_4 PF08386.5 EDO01877.1 - 0.46 10.4 4.0 0.54 10.1 0.4 2.4 1 1 1 2 2 2 0 TAP-like protein Sporozoite_P67 PF05642.6 EDO01878.1 - 0.11 10.3 8.9 0.14 9.9 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Activator_LAG-3 PF11498.3 EDO01878.1 - 0.27 9.9 1.6 0.36 9.5 1.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 KAR9 PF08580.5 EDO01878.1 - 0.69 8.1 4.0 0.81 7.8 2.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 OmpH PF03938.9 EDO01879.1 - 0.56 10.1 6.7 0.82 9.5 4.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EDO01879.1 - 2.1 7.3 12.0 3.3 6.6 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 EDO01879.1 - 5.7 6.0 8.0 8.2 5.5 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG4 PF08318.7 EDO01880.1 - 0.13 11.0 0.3 0.26 10.0 0.2 1.4 1 0 0 1 1 1 0 COG4 transport protein Pescadillo_N PF06732.6 EDO01881.1 - 3.4e-112 374.2 0.2 3.4e-112 374.2 0.1 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EDO01881.1 - 1.2e-09 38.1 0.0 4.4e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TMEM223 PF14640.1 EDO01883.1 - 0.14 12.0 1.4 0.25 11.2 0.0 2.0 2 1 0 2 2 2 0 Transmembrane protein 223 CAF-1_p150 PF11600.3 EDO01883.1 - 0.37 10.1 33.0 0.79 9.0 22.9 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRN9 PF10680.4 EDO01884.1 - 3.6e-24 84.2 0.2 1.4e-23 82.3 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor AT_hook PF02178.14 EDO01884.1 - 2.6 8.0 10.4 11 6.0 0.2 3.8 3 0 0 3 3 3 0 AT hook motif FLO_LFY PF01698.11 EDO01885.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein ScpA_ScpB PF02616.9 EDO01886.1 - 1.6 8.2 5.5 2.5 7.6 3.8 1.2 1 0 0 1 1 1 0 ScpA/B protein DUF605 PF04652.11 EDO01891.1 - 0.021 14.2 15.0 0.021 14.2 10.4 1.2 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 EDO01891.1 - 2.7 6.4 11.9 3.8 6.0 8.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UQ_con PF00179.21 EDO01892.1 - 5.7e-27 93.8 0.1 8e-27 93.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EDO01893.1 - 1.1e-46 159.7 0.1 1.4e-46 159.4 0.1 1.1 1 0 0 1 1 1 1 Surface antigen 4HBT_2 PF13279.1 EDO01894.1 - 1.6e-06 28.5 0.1 2.1e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EDO01894.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily DUF3328 PF11807.3 EDO01896.1 - 1.7e-40 138.9 1.8 2.2e-40 138.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EDO01897.1 - 1.1e-26 93.3 32.5 4.6e-17 61.7 9.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EDO01898.1 - 1.4e-14 54.6 0.0 4e-14 53.1 0.0 1.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO01898.1 - 5.5e-14 51.2 0.0 2.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDO01898.1 - 9.3e-08 31.3 0.0 7.8e-06 25.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDO01898.1 - 2.9e-05 24.0 0.0 0.00017 21.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO01898.1 - 3.9e-05 23.5 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO01898.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EDO01898.1 - 0.0073 16.6 0.6 1.1 9.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO01898.1 - 0.097 11.5 0.0 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Herpes_UL31 PF02718.9 EDO01899.1 - 0.0043 15.7 0.0 0.0053 15.4 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL31-like protein GAGA PF09237.6 EDO01900.1 - 0.063 12.8 0.1 0.098 12.2 0.1 1.4 1 0 0 1 1 1 0 GAGA factor FAD_binding_3 PF01494.14 EDO01902.1 - 3.1e-26 92.2 0.2 5.3e-16 58.6 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDO01902.1 - 9.7e-05 21.4 0.8 0.1 11.4 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO01902.1 - 0.00014 22.2 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO01902.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDO01902.1 - 0.0027 16.8 0.0 0.0091 15.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EDO01902.1 - 0.011 14.2 0.3 0.36 9.2 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 EDO01902.1 - 0.016 15.2 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EDO01902.1 - 0.066 13.2 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EDO01902.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MutS_V PF00488.16 EDO01903.1 - 7.9e-39 133.4 0.6 3e-27 95.5 0.0 3.1 1 1 1 2 2 2 2 MutS domain V Sec23_trunk PF04811.10 EDO01903.1 - 0.068 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain AAA_29 PF13555.1 EDO01903.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2958 PF11171.3 EDO01904.1 - 0.0018 18.1 0.0 0.0018 18.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2958) WD40 PF00400.27 EDO01905.1 - 4e-78 254.7 17.6 5.8e-13 48.1 0.4 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EDO01905.1 - 3.4e-10 39.9 0.6 6.5e-05 22.7 0.0 3.7 1 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDO01905.1 - 8.1e-07 27.5 6.4 0.0066 14.6 0.0 4.7 3 1 0 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EDO01905.1 - 0.0022 17.9 0.1 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain PD40 PF07676.7 EDO01905.1 - 0.083 12.5 0.6 77 3.1 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Thiolase_N PF00108.18 EDO01906.1 - 9e-74 247.7 0.2 1.5e-73 246.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDO01906.1 - 3.1e-31 107.3 0.7 4.8e-31 106.7 0.0 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain Fer2_3 PF13085.1 EDO01909.1 - 4.5e-31 106.9 0.0 8.7e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDO01909.1 - 3.9e-09 36.7 6.6 3.9e-09 36.7 4.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDO01909.1 - 9.5e-09 35.1 4.4 9.5e-09 35.1 3.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDO01909.1 - 0.00035 20.9 1.6 0.00035 20.9 1.1 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDO01909.1 - 0.00037 20.2 3.4 0.00037 20.2 2.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDO01909.1 - 0.00096 19.3 4.5 0.037 14.2 0.5 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EDO01909.1 - 0.0014 18.9 3.8 0.0014 18.9 2.6 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EDO01909.1 - 0.011 15.5 0.4 0.011 15.5 0.3 2.5 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EDO01909.1 - 1.6 9.3 5.5 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Toxin_8 PF07365.7 EDO01910.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha conotoxin precursor Peptidase_C23 PF05379.6 EDO01911.1 - 0.06 13.3 0.1 0.06 13.3 0.0 1.0 1 0 0 1 1 1 0 Carlavirus endopeptidase Peptidase_M1 PF01433.15 EDO01913.1 - 1.8e-143 478.3 0.3 2.4e-143 477.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDO01913.1 - 8.7e-92 307.8 0.0 1.4e-91 307.1 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDO01913.1 - 4.9e-20 71.8 0.1 1e-19 70.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EDO01913.1 - 0.014 15.0 0.2 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DUF515 PF04415.7 EDO01918.1 - 3.4 5.7 10.9 3.6 5.7 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF566 PF04484.7 EDO01918.1 - 5 6.5 7.2 5.6 6.3 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SSP160 PF06933.6 EDO01918.1 - 7.5 4.3 24.9 8.1 4.2 17.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 EDO01919.1 - 3.5e-15 55.5 41.0 1.8e-11 43.3 11.9 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily RNase_Zc3h12a_2 PF14626.1 EDO01922.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain zf-CSL PF05207.8 EDO01923.1 - 1.3e-19 69.4 0.7 2.1e-19 68.7 0.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EDO01923.1 - 8e-13 47.9 0.0 1.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Mnd1 PF03962.10 EDO01924.1 - 4.5e-56 189.4 4.3 5.4e-56 189.2 3.0 1.0 1 0 0 1 1 1 1 Mnd1 family AKNA PF12443.3 EDO01924.1 - 0.029 14.3 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor BBS2_C PF14782.1 EDO01924.1 - 0.067 11.7 3.3 0.084 11.4 2.3 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PEP-utilisers_N PF05524.8 EDO01924.1 - 0.15 11.8 1.4 0.34 10.6 0.4 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal NDUF_B5 PF09781.4 EDO01924.1 - 0.24 10.6 1.3 0.35 10.1 0.9 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit FA_desaturase PF00487.19 EDO01928.1 - 1.7e-13 50.6 9.0 2.6e-13 50.0 6.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EDO01928.1 - 2.3e-07 30.9 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) U1snRNP70_N PF12220.3 EDO01929.1 - 0.56 10.5 5.7 9.5 6.6 0.1 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DEAD PF00270.24 EDO01930.1 - 1.1e-39 135.6 0.0 3.1e-39 134.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO01930.1 - 1.8e-25 88.5 0.2 4.6e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2984 PF11203.3 EDO01930.1 - 0.063 13.3 0.9 0.35 11.0 0.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) DUF2986 PF11661.3 EDO01930.1 - 0.81 10.0 11.1 0.11 12.8 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) zf-C2H2 PF00096.21 EDO01934.1 - 2.8e-10 39.8 20.4 1.8e-05 24.7 2.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO01934.1 - 9.8e-08 31.8 17.7 0.00068 19.7 5.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO01934.1 - 1e-07 31.8 15.9 4e-06 26.8 4.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EDO01934.1 - 2.5e-05 24.2 0.9 2.5e-05 24.2 0.7 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO01934.1 - 5.8e-05 23.1 9.6 0.0033 17.5 1.7 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO01934.1 - 0.00093 19.0 1.4 0.00093 19.0 1.0 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger Elf1 PF05129.8 EDO01934.1 - 0.47 10.1 6.3 4.6 7.0 0.8 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ATP_bind_4 PF01902.12 EDO01935.1 - 1.4e-23 83.4 0.0 1.1e-18 67.4 0.0 2.9 2 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EDO01935.1 - 7.3e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP ThiI PF02568.9 EDO01935.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) HPP PF04982.8 EDO01938.1 - 2.5e-36 124.1 5.6 4.3e-36 123.3 3.9 1.4 1 0 0 1 1 1 1 HPP family DUF2893 PF11459.3 EDO01938.1 - 0.047 13.4 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Methyltransf_15 PF09445.5 EDO01939.1 - 1.7e-41 141.4 0.0 2.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EDO01939.1 - 5.6e-07 29.2 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO01939.1 - 1.3e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO01939.1 - 2.7e-06 27.9 0.0 4.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EDO01939.1 - 2.8e-06 26.8 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 EDO01939.1 - 0.00072 18.6 0.0 0.00094 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EDO01939.1 - 0.00074 19.1 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EDO01939.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein DNA_methylase PF00145.12 EDO01939.1 - 0.0029 16.7 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_4 PF02390.12 EDO01939.1 - 0.0039 16.2 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDO01939.1 - 0.0094 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.14 EDO01939.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family GRASP55_65 PF04495.9 EDO01940.1 - 6.8e-50 168.6 0.0 1.9e-48 163.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DAD PF02109.11 EDO01941.1 - 6.4e-39 132.4 0.6 8.1e-39 132.1 0.4 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.1 EDO01941.1 - 0.062 13.0 0.4 0.098 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Pex14_N PF04695.8 EDO01941.1 - 0.071 13.1 0.3 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tmemb_14 PF03647.8 EDO01942.1 - 1.8e-25 89.1 6.5 2.1e-25 88.9 4.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EDO01942.1 - 0.016 15.4 0.9 0.027 14.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) Cmc1 PF08583.5 EDO01943.1 - 6.8e-18 64.2 8.6 7.9e-18 64.0 6.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NYD-SP28 PF14772.1 EDO01943.1 - 0.072 13.1 3.5 0.17 11.9 1.3 2.0 2 0 0 2 2 2 0 Sperm tail zf-TAZ PF02135.11 EDO01943.1 - 0.5 10.4 4.2 0.58 10.2 2.9 1.3 1 0 0 1 1 1 0 TAZ zinc finger Ribosomal_L30_N PF08079.7 EDO01943.1 - 2.3 8.3 8.1 3.3 7.7 5.6 1.2 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Prefoldin_2 PF01920.15 EDO01944.1 - 1e-11 44.5 0.2 1.8e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit NT5C PF06941.7 EDO01944.1 - 0.00012 21.6 0.3 0.0011 18.5 0.0 1.9 1 1 1 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF2205 PF10224.4 EDO01944.1 - 0.1 12.1 0.4 0.2 11.2 0.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) CBFD_NFYB_HMF PF00808.18 EDO01945.1 - 3.3e-29 100.7 1.0 4.5e-29 100.3 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO01945.1 - 3.3e-07 30.3 0.1 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EDO01945.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EDO01945.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EDO01945.1 - 0.051 13.8 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RRN3 PF05327.6 EDO01946.1 - 3.9e-160 533.6 11.4 5.8e-136 453.8 0.0 3.0 2 1 1 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 COesterase PF00135.23 EDO01947.1 - 6.1e-43 147.3 0.4 2.8e-42 145.1 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDO01947.1 - 0.00019 21.1 0.1 0.0092 15.5 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDO01947.1 - 0.0014 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BTB PF00651.26 EDO01948.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GPI-anchored PF10342.4 EDO01950.1 - 2.8e-19 69.3 0.5 2.8e-19 69.3 0.4 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EDO01950.1 - 0.0022 17.5 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2318 PF10080.4 EDO01950.1 - 0.23 11.2 1.2 21 4.9 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF4223 PF13978.1 EDO01950.1 - 3.9 7.2 7.8 25 4.6 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4223) Ribosomal_L19e PF01280.15 EDO01953.1 - 1.3 8.7 7.8 1.3 8.7 2.3 2.2 2 0 0 2 2 2 0 Ribosomal protein L19e Arabino_trans_C PF14896.1 EDO01954.1 - 0.035 12.7 1.8 0.044 12.3 1.3 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain Abhydrolase_6 PF12697.2 EDO01955.1 - 1.4e-21 77.4 0.4 2e-21 76.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO01955.1 - 2.3e-09 37.1 0.0 4.2e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EDO01955.1 - 0.00024 21.4 0.0 0.00039 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EDO01955.1 - 0.00027 20.5 0.0 0.046 13.2 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDO01955.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2417 PF10329.4 EDO01956.1 - 5.4e-89 297.5 2.2 7.9e-89 297.0 1.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EDO01956.1 - 5.7e-07 29.6 0.1 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC2_membrane_3 PF12698.2 EDO01956.1 - 0.035 13.1 12.8 0.059 12.4 8.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA PF00004.24 EDO01957.1 - 3.1e-16 59.7 0.0 7.9e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EDO01957.1 - 7.9e-14 51.6 0.0 9.8e-13 48.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EDO01957.1 - 1.5e-11 44.1 0.0 2.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EDO01957.1 - 5.5e-11 41.8 0.1 1.2e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDO01957.1 - 3.3e-06 27.2 0.0 4.8e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO01957.1 - 6.4e-06 25.9 0.0 8.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO01957.1 - 1.5e-05 24.1 0.0 5.1e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDO01957.1 - 2.3e-05 24.0 0.0 5.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDO01957.1 - 2.8e-05 24.1 0.0 0.00036 20.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EDO01957.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EDO01957.1 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 EDO01957.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EDO01957.1 - 0.0015 19.3 0.0 0.0057 17.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EDO01957.1 - 0.0022 17.1 0.0 0.08 12.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO01957.1 - 0.0036 16.9 0.3 0.011 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO01957.1 - 0.0036 17.0 0.0 0.02 14.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EDO01957.1 - 0.0066 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EDO01957.1 - 0.0082 15.6 0.2 0.046 13.1 0.0 2.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EDO01957.1 - 0.0097 15.3 0.6 0.029 13.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO01957.1 - 0.013 15.8 0.0 0.042 14.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDO01957.1 - 0.017 14.7 0.0 0.074 12.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.8 EDO01957.1 - 0.02 13.6 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 EDO01957.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDO01957.1 - 0.042 13.2 0.1 0.67 9.3 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EDO01957.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EDO01957.1 - 0.074 12.6 0.0 0.3 10.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDO01957.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO01957.1 - 0.087 12.0 0.0 3.9 6.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EDO01957.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO01957.1 - 0.13 10.9 0.0 3.9 6.1 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Sec63 PF02889.11 EDO01959.1 - 2.2e-199 661.1 0.0 6.1e-109 364.0 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDO01959.1 - 1.8e-52 177.2 0.0 1.5e-30 105.9 0.0 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO01959.1 - 6.1e-16 58.7 0.0 1.3e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO01959.1 - 7.3e-10 38.5 0.0 2.6e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO01959.1 - 6.6e-08 32.7 0.4 0.0046 17.0 0.1 3.2 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EDO01959.1 - 0.0053 15.7 0.0 1.7 7.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EDO01959.1 - 0.014 14.8 0.1 12 5.2 0.0 3.9 4 1 1 5 5 5 0 AAA-like domain PhoH PF02562.11 EDO01959.1 - 0.02 14.0 0.0 0.46 9.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 EDO01959.1 - 0.037 13.3 0.0 7.8 5.7 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain FtsK_SpoIIIE PF01580.13 EDO01959.1 - 0.075 12.5 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PWWP PF00855.12 EDO01960.1 - 1.1e-10 41.5 0.5 1.1e-10 41.5 0.4 2.8 2 1 0 2 2 2 1 PWWP domain RTC PF01137.16 EDO01961.1 - 3.2e-31 107.8 0.1 4.5e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EDO01961.1 - 1.4e-30 105.3 0.1 2.5e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.5 EDO01962.1 - 3.4e-43 146.2 1.2 4.7e-43 145.8 0.8 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) tRNA-synt_2d PF01409.15 EDO01965.1 - 1.3e-86 289.8 0.0 1.8e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EDO01965.1 - 3.5e-06 26.0 0.3 0.00015 20.6 0.1 2.9 2 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EDO01965.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4187 PF13821.1 EDO01966.1 - 1.4e-18 66.1 1.7 8.5e-18 63.7 1.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EDO01966.1 - 2e-08 33.8 1.2 2e-08 33.8 0.9 1.8 2 0 0 2 2 2 1 G-patch domain PPR_3 PF13812.1 EDO01967.1 - 6.1e-08 32.3 0.4 3.3 8.2 0.0 6.8 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDO01967.1 - 9.9e-08 31.8 0.9 0.34 10.9 0.0 5.6 6 0 0 6 6 6 2 PPR repeat family TPR_14 PF13428.1 EDO01967.1 - 5.1e-06 26.6 1.4 0.65 10.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 EDO01967.1 - 0.00011 21.9 9.7 0.3 11.1 0.0 5.9 7 0 0 7 7 7 2 PPR repeat TPR_19 PF14559.1 EDO01967.1 - 0.0025 18.0 0.4 0.38 11.1 0.0 3.8 2 2 0 2 2 2 1 Tetratricopeptide repeat PPR_1 PF12854.2 EDO01967.1 - 0.017 14.5 9.1 1 8.8 0.1 5.0 5 0 0 5 5 5 0 PPR repeat ABM PF03992.11 EDO01968.1 - 0.042 13.8 0.8 0.068 13.2 0.5 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Rootletin PF15035.1 EDO01968.1 - 0.084 12.8 0.8 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1192 PF06698.6 EDO01968.1 - 0.09 12.6 3.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ORC3_N PF07034.6 EDO01969.1 - 1.1e-34 119.9 2.3 1.1e-33 116.6 1.6 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Sec66 PF09802.4 EDO01970.1 - 2.1e-80 268.6 0.0 2.5e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 NPL4 PF05021.10 EDO01971.1 - 4.1e-130 433.4 0.0 5.3e-130 433.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EDO01971.1 - 5.6e-73 243.4 0.2 8.4e-73 242.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EDO01971.1 - 0.0018 18.5 0.0 0.008 16.4 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ctr PF04145.10 EDO01974.1 - 6.1e-28 97.6 12.9 5.6e-27 94.5 8.9 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Neurensin PF14927.1 EDO01974.1 - 0.0013 18.0 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Neurensin Ni_hydr_CYTB PF01292.15 EDO01974.1 - 0.0099 15.2 1.8 0.012 15.0 1.2 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF2434 PF10361.4 EDO01974.1 - 0.017 14.2 0.4 0.023 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Ion_trans_N PF08412.5 EDO01974.1 - 0.11 11.7 0.9 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein N-terminal 3-HAO PF06052.7 EDO01975.1 - 8.4e-63 210.2 0.0 9.6e-63 210.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EDO01975.1 - 1.6e-06 27.5 0.0 2.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EDO01975.1 - 9.4e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Nudix_N_2 PF14803.1 EDO01975.1 - 0.0023 17.5 2.3 0.14 11.8 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal DZR PF12773.2 EDO01975.1 - 0.018 14.8 3.4 0.034 13.9 2.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EDO01975.1 - 0.02 14.0 1.1 4.7 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cupin_1 PF00190.17 EDO01975.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin TF_Zn_Ribbon PF08271.7 EDO01975.1 - 0.075 12.3 0.2 15 5.0 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EDO01975.1 - 7.5 6.6 7.0 1.4 8.9 0.9 2.2 1 1 1 2 2 2 0 Zinc ribbon domain FAA_hydrolase PF01557.13 EDO01976.1 - 5.4e-51 173.1 0.0 6.7e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TcdB_N PF12918.2 EDO01977.1 - 0.11 12.5 0.4 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain CPSase_L_D2 PF02786.12 EDO01978.1 - 9.7e-85 283.1 0.0 1.9e-84 282.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EDO01978.1 - 2.7e-36 124.0 0.0 6.8e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EDO01978.1 - 7.4e-16 58.2 0.0 2.1e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDO01978.1 - 5.8e-14 52.2 0.0 9.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO01978.1 - 2.5e-12 46.1 0.0 2e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDO01978.1 - 2.5e-09 36.7 0.0 4.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO01978.1 - 8.5e-07 28.5 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 EDO01978.1 - 0.0095 15.1 0.1 0.036 13.2 0.1 2.0 1 1 1 2 2 2 1 ATP-grasp domain MA-Mit PF09245.5 EDO01978.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen GARS_A PF01071.14 EDO01978.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 EDO01979.1 - 2.4e-23 82.5 0.0 3.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EDO01979.1 - 4.3e-22 78.7 0.1 9.5e-22 77.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO01979.1 - 3.1e-11 42.5 0.0 1.2e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDO01979.1 - 9.6e-10 38.0 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO01979.1 - 1e-09 38.1 0.1 1.9e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EDO01979.1 - 9.6e-07 28.4 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain CPSase_L_chain PF00289.17 EDO01979.1 - 1.2e-06 28.5 0.0 5.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain GARS_A PF01071.14 EDO01979.1 - 0.0064 16.0 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.17 EDO01979.1 - 0.02 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain EAP30 PF04157.11 EDO01979.1 - 0.16 11.0 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family PWI PF01480.12 EDO01980.1 - 1.9e-29 101.5 0.0 2.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 PWI domain DUF936 PF06075.7 EDO01980.1 - 0.042 12.7 28.2 0.062 12.2 19.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF605 PF04652.11 EDO01980.1 - 0.44 9.8 16.8 0.58 9.5 11.6 1.3 1 0 0 1 1 1 0 Vta1 like NuA4 PF09340.5 EDO01981.1 - 7.7e-22 76.7 0.0 1.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Cupin_8 PF13621.1 EDO01982.1 - 1.6e-14 54.0 0.2 2e-13 50.4 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDO01982.1 - 3.9e-09 36.7 0.5 0.00081 19.6 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.2 EDO01982.1 - 2.4e-05 23.9 0.3 5.6e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO01982.1 - 0.005 16.4 0.2 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain IRF-3 PF10401.4 EDO01982.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 DEAD PF00270.24 EDO01983.1 - 2.1e-44 151.0 1.2 3.8e-44 150.1 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO01983.1 - 1.4e-27 95.3 0.2 6.1e-27 93.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO01983.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDO01983.1 - 0.003 17.1 0.1 0.0093 15.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO01983.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EDO01983.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EDO01983.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EDO01983.1 - 0.08 12.6 0.1 0.41 10.4 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain CobA_CobO_BtuR PF02572.10 EDO01983.1 - 0.084 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 EDO01983.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Tropomyosin PF00261.15 EDO01984.1 - 0.0017 17.4 8.9 0.0041 16.2 6.2 1.6 1 0 0 1 1 1 1 Tropomyosin Cauli_AT PF03233.8 EDO01984.1 - 0.01 15.5 8.0 0.013 15.1 2.9 2.2 2 0 0 2 2 2 0 Aphid transmission protein DUF342 PF03961.8 EDO01984.1 - 0.012 14.0 2.5 0.023 13.1 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Retrotrans_gag PF03732.12 EDO01984.1 - 0.019 15.0 2.7 0.38 10.8 0.0 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein DUF972 PF06156.8 EDO01984.1 - 0.1 12.9 5.4 0.32 11.3 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Complex1_LYR_2 PF13233.1 EDO01984.1 - 0.17 12.3 4.8 0.17 12.3 0.1 2.2 2 0 0 2 2 2 0 Complex1_LYR-like Spc7 PF08317.6 EDO01984.1 - 0.26 9.9 9.7 0.031 12.9 3.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EDO01984.1 - 0.36 10.3 9.9 0.077 12.5 4.4 1.7 2 0 0 2 2 2 0 IncA protein DUF4337 PF14235.1 EDO01984.1 - 0.51 10.1 2.9 1.6 8.5 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sipho_Gp157 PF05565.6 EDO01984.1 - 0.83 9.2 9.0 0.45 10.0 3.5 2.2 2 0 0 2 2 2 0 Siphovirus Gp157 APG6 PF04111.7 EDO01984.1 - 1.5 7.8 11.4 0.5 9.3 5.8 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EDO01984.1 - 9.2 3.9 6.6 2 6.1 2.4 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EDO01985.1 - 1.1e-39 136.1 0.0 8.4e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO01985.1 - 1.5e-16 60.2 0.0 7.2e-16 58.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO01985.1 - 9.4e-06 25.5 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO01985.1 - 0.093 11.6 0.0 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like RicinB_lectin_2 PF14200.1 EDO01986.1 - 0.0091 16.3 0.0 0.038 14.3 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF4448 PF14610.1 EDO01987.1 - 0.00016 21.2 0.1 0.00055 19.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EDO01987.1 - 0.00076 18.7 2.3 0.0014 17.8 1.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EDO01987.1 - 0.02 14.1 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EDO01987.1 - 0.16 12.3 0.1 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.8 EDO01987.1 - 0.22 10.1 6.1 0.099 11.2 2.5 1.6 1 1 1 2 2 2 0 Giardia variant-specific surface protein adh_short PF00106.20 EDO01989.1 - 8.4e-11 42.0 0.0 9.8e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO01989.1 - 5.1e-07 29.7 0.0 6e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDO01989.1 - 6.6e-05 22.9 0.0 8.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDO01989.1 - 0.0072 16.0 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EDO01989.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EDO01989.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family UBA PF00627.26 EDO01989.1 - 0.086 12.7 0.6 12 5.8 0.0 2.8 3 0 0 3 3 3 0 UBA/TS-N domain Mgm101p PF06420.7 EDO01990.1 - 6.9e-73 243.5 0.3 3.1e-42 143.8 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 EDO01991.1 - 1.5e-138 461.5 0.0 1.9e-138 461.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EDO01991.1 - 2.4e-21 76.0 0.0 4e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_47 PF01532.15 EDO01992.1 - 1.5e-130 435.9 0.0 1.7e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PDZ_assoc PF10600.4 EDO01994.1 - 0.0028 17.9 0.6 0.0039 17.4 0.4 1.3 1 1 0 1 1 1 1 PDZ-associated domain of NMDA receptors Glycos_transf_1 PF00534.15 EDO01995.1 - 2.7e-10 39.9 0.0 4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDO01995.1 - 4.6e-05 23.5 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDO01995.1 - 0.028 14.6 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferases group 1 SCIMP PF15050.1 EDO01996.1 - 0.076 12.9 0.2 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein Peptidase_C74 PF12387.3 EDO01996.1 - 0.11 11.5 0.1 0.3 10.2 0.1 1.6 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Polysacc_deac_1 PF01522.16 EDO01997.1 - 0.049 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Glyco_hydro_114 PF03537.8 EDO01999.1 - 6.3e-18 64.3 0.0 1.1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spherulin4 PF12138.3 EDO02000.1 - 2e-65 220.7 0.0 2.2e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.16 EDO02001.1 - 7.5e-34 117.1 0.0 3e-32 111.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EDO02001.1 - 4.5e-18 64.9 0.1 1.2e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EDO02001.1 - 4.1e-08 32.4 0.0 2.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EDO02001.1 - 1.1e-07 31.0 0.0 0.0053 15.6 0.0 3.9 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EDO02001.1 - 9.8e-07 27.7 0.1 0.00015 20.5 0.1 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.19 EDO02001.1 - 0.00092 18.2 0.6 0.0018 17.2 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase RmlD_sub_bind PF04321.12 EDO02001.1 - 0.0014 17.6 0.0 0.014 14.3 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_8 PF13450.1 EDO02001.1 - 0.0025 17.7 0.5 0.38 10.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EDO02001.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EDO02001.1 - 0.044 13.7 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EDO02001.1 - 0.081 12.2 0.8 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 EDO02001.1 - 0.13 11.9 0.2 0.95 9.1 0.1 2.1 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EDO02001.1 - 0.14 11.4 0.1 0.43 9.7 0.1 1.8 1 0 0 1 1 1 0 NmrA-like family NIR_SIR PF01077.17 EDO02003.1 - 8.5e-31 106.4 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.10 EDO02003.1 - 3.5e-15 55.8 1.9 4.9e-12 45.7 1.7 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 EDO02003.1 - 1.4e-09 37.5 0.0 7.6e-07 28.8 0.0 2.9 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EDO02003.1 - 4.5e-09 35.7 0.0 1.4e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.22 EDO02003.1 - 3.8e-08 33.6 0.2 1.1e-07 32.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EDO02003.1 - 8.8e-08 31.6 0.1 4.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.9 EDO02003.1 - 2.6e-07 30.7 0.7 1.4e-06 28.3 0.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2014 PF09427.5 EDO02004.1 - 1.2e-113 378.5 1.4 1.8e-113 378.0 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EDO02004.1 - 4e-11 42.4 1.9 4e-11 42.4 1.3 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2681 PF10883.3 EDO02004.1 - 0.18 12.0 1.4 0.68 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ERM PF00769.14 EDO02006.1 - 0.0064 16.0 13.0 0.0073 15.8 9.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Peptidase_C25 PF01364.13 EDO02006.1 - 0.067 12.1 0.4 0.071 12.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase family C25 Selenoprotein_S PF06936.6 EDO02006.1 - 0.5 9.8 4.8 0.7 9.4 3.3 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) IncA PF04156.9 EDO02006.1 - 1.2 8.6 9.4 1.9 8.0 6.5 1.2 1 0 0 1 1 1 0 IncA protein ABC2_membrane PF01061.19 EDO02007.1 - 5.5e-84 280.5 56.1 1.2e-42 145.4 17.1 2.6 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EDO02007.1 - 1.3e-28 98.6 7.7 1.4e-25 88.8 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EDO02007.1 - 3.8e-27 95.2 0.0 8.5e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EDO02007.1 - 1.5e-06 27.5 37.3 5.1e-05 22.4 12.7 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EDO02007.1 - 1.8e-06 27.8 0.1 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO02007.1 - 4.7e-06 26.1 0.1 0.007 15.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EDO02007.1 - 2.3e-05 25.2 0.0 0.022 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO02007.1 - 0.00014 21.2 0.1 0.0073 15.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDO02007.1 - 0.00025 20.2 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EDO02007.1 - 0.00052 19.5 2.9 0.0049 16.3 0.3 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EDO02007.1 - 0.00065 19.8 0.3 0.28 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EDO02007.1 - 0.0013 18.3 0.6 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EDO02007.1 - 0.0027 17.4 0.5 0.88 9.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EDO02007.1 - 0.0041 17.4 0.1 0.43 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO02007.1 - 0.0097 15.5 0.3 4.1 7.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EDO02007.1 - 0.011 15.4 0.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EDO02007.1 - 0.013 15.4 0.2 0.58 10.1 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EDO02007.1 - 0.014 15.3 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDO02007.1 - 0.015 14.8 0.2 2.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EDO02007.1 - 0.028 14.3 0.0 0.13 12.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDO02007.1 - 0.033 13.6 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EDO02007.1 - 0.044 13.9 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EDO02007.1 - 0.095 13.2 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Mor PF08765.6 EDO02007.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Mor transcription activator family AAA_10 PF12846.2 EDO02007.1 - 0.12 11.8 0.2 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Syja_N PF02383.13 EDO02011.1 - 3.7e-74 249.3 0.2 1.8e-71 240.5 0.0 2.8 2 1 1 3 3 3 2 SacI homology domain Exo_endo_phos PF03372.18 EDO02011.1 - 2.1e-21 76.9 0.1 3.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HisKA PF00512.20 EDO02013.1 - 3.4e-05 23.7 0.0 8.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Lipase_3 PF01764.20 EDO02014.1 - 6.7e-26 90.5 0.0 5.1e-25 87.7 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDO02014.1 - 0.0072 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase PF00151.14 EDO02014.1 - 0.0098 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 EDO02014.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EDO02014.1 - 0.017 15.3 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EDO02014.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FAA_hydrolase PF01557.13 EDO02016.1 - 5.5e-58 195.9 0.0 7.8e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PAS_5 PF07310.8 EDO02016.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PAS domain DUF2294 PF10057.4 EDO02018.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) RhoGAP PF00620.22 EDO02020.1 - 1.2e-41 141.8 0.0 2.5e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EDO02020.1 - 1.1e-11 44.8 0.0 2.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EDO02020.1 - 2.6e-09 37.2 0.0 6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 EDO02020.1 - 0.026 13.8 3.1 0.046 12.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PH_7 PF15408.1 EDO02020.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.1 EDO02020.1 - 0.082 12.9 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_16 PF00722.16 EDO02021.1 - 1.8e-34 118.6 1.1 1.8e-34 118.6 0.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DEAD PF00270.24 EDO02025.1 - 1e-21 77.1 0.0 1.1e-20 73.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO02025.1 - 7.3e-18 64.2 0.4 2.9e-17 62.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO02025.1 - 7.4e-05 22.6 1.1 0.00044 20.1 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Ammonium_transp PF00909.16 EDO02026.1 - 1.3e-118 395.9 28.9 1.5e-118 395.7 20.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SieB PF14163.1 EDO02026.1 - 0.12 11.9 3.6 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Superinfection exclusion protein B DIOX_N PF14226.1 EDO02029.1 - 1.8e-26 92.9 0.0 3e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDO02029.1 - 2.3e-19 69.4 0.0 5.1e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FMO-like PF00743.14 EDO02032.1 - 7.3e-29 100.3 0.0 2.7e-14 52.2 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDO02032.1 - 5.4e-19 69.0 0.0 4.2e-18 66.1 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO02032.1 - 4e-08 32.5 0.0 2.9e-05 23.1 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDO02032.1 - 3.1e-06 27.1 0.0 0.00064 19.6 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO02032.1 - 6.9e-06 25.9 0.1 0.001 18.8 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDO02032.1 - 0.00015 21.7 0.2 0.00053 19.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO02032.1 - 0.0056 15.7 0.1 0.029 13.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EDO02032.1 - 0.069 11.6 0.2 0.2 10.1 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein WD40 PF00400.27 EDO02034.1 - 3.7e-20 70.9 14.2 3.1e-08 33.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EDO02034.1 - 0.0099 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity RRM_5 PF13893.1 EDO02035.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EDO02035.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.8 2 1 0 2 2 2 0 Calcipressin Mito_fiss_reg PF05308.6 EDO02035.1 - 0.02 14.2 0.8 0.02 14.2 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.17 EDO02035.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 EDO02035.1 - 0.14 12.4 2.7 0.16 12.2 1.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Glyco_hydro_47 PF01532.15 EDO02037.1 - 1.3e-165 551.4 0.0 1.7e-165 551.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EDO02037.1 - 0.0024 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_88 PF07470.8 EDO02037.1 - 0.013 14.6 0.2 0.05 12.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 AA_permease PF00324.16 EDO02038.1 - 4.7e-130 434.1 38.2 5.7e-130 433.8 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO02038.1 - 7.5e-33 113.6 37.5 1e-32 113.2 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_5 PF06946.6 EDO02038.1 - 1.6 8.9 7.1 0.43 10.7 0.2 3.1 3 1 0 3 3 3 0 Phage holin His_Phos_2 PF00328.17 EDO02039.1 - 1.9e-13 50.5 3.4 1.4e-11 44.3 0.3 3.7 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) AAA_22 PF13401.1 EDO02040.1 - 1e-13 51.5 0.1 2.7e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO02040.1 - 1.2e-12 48.2 0.3 5e-11 42.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EDO02040.1 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EDO02040.1 - 2.2e-05 24.1 0.0 0.00013 21.5 0.0 2.4 1 1 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 EDO02040.1 - 9.3e-05 22.1 0.9 0.005 16.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EDO02040.1 - 0.00019 21.2 0.2 0.00077 19.2 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EDO02040.1 - 0.00057 19.7 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EDO02040.1 - 0.0017 17.4 0.6 0.044 12.7 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain Miro PF08477.8 EDO02040.1 - 0.0054 17.2 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 EDO02040.1 - 0.0072 16.4 0.1 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 EDO02040.1 - 0.0083 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EDO02040.1 - 0.017 14.1 0.0 0.049 12.6 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO02040.1 - 0.02 15.6 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EDO02040.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 EDO02040.1 - 0.028 14.1 0.1 0.25 11.1 0.0 2.6 3 0 0 3 3 2 0 Part of AAA domain AAA_18 PF13238.1 EDO02040.1 - 0.034 14.4 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDO02040.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDO02040.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EDO02040.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA12 PF10443.4 EDO02040.1 - 0.084 11.3 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein AAA_28 PF13521.1 EDO02040.1 - 0.085 12.8 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EDO02040.1 - 0.099 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EDO02040.1 - 0.12 11.0 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 EDO02040.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WW PF00397.21 EDO02041.1 - 7.9e-09 35.2 0.3 2e-08 33.9 0.2 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EDO02041.1 - 0.00011 20.9 0.1 0.00023 19.8 0.1 1.4 2 0 0 2 2 2 1 PhoD-like phosphatase PMM PF03332.8 EDO02042.1 - 6.6e-60 202.4 0.0 7.7e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.8 EDO02042.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Homeobox PF00046.24 EDO02046.1 - 1.3e-12 47.1 6.1 2.6e-12 46.1 4.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO02046.1 - 0.04 13.6 0.2 0.13 12.0 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain Peptidase_S10 PF00450.17 EDO02047.1 - 1.5e-71 241.8 1.0 4.4e-50 171.0 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Ras PF00071.17 EDO02048.1 - 1.1e-48 164.7 0.0 1.3e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO02048.1 - 3e-14 53.5 0.0 5.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO02048.1 - 6.8e-11 41.7 0.0 9.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO02048.1 - 0.00036 19.7 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EDO02048.1 - 0.00053 20.1 0.1 0.0028 17.8 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Pox_A32 PF04665.7 EDO02048.1 - 0.027 13.7 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EDO02048.1 - 0.056 12.1 2.0 0.7 8.5 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EDO02048.1 - 0.073 13.2 0.2 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDO02048.1 - 0.087 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDO02048.1 - 0.096 11.5 0.0 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRPRB PF09439.5 EDO02048.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PDZ_2 PF13180.1 EDO02049.1 - 5.3e-08 32.6 0.1 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 EDO02049.1 - 2.4e-05 24.3 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EDO02049.1 - 0.00021 21.3 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2560 PF10834.3 EDO02050.1 - 0.043 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) RhoGEF PF00621.15 EDO02051.1 - 1.9e-09 37.6 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Nbs1_C PF08599.5 EDO02053.1 - 0.055 13.3 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 PLA2_B PF01735.13 EDO02054.1 - 1.2e-189 630.6 4.8 1.4e-189 630.3 3.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTCB-BRCT PF12738.2 EDO02055.1 - 0.00011 21.9 0.1 0.00022 21.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain AT_hook PF02178.14 EDO02055.1 - 0.0044 16.5 4.1 0.85 9.5 0.2 3.5 2 0 0 2 2 2 2 AT hook motif WD40 PF00400.27 EDO02056.1 - 2.4e-08 33.5 0.8 0.15 11.9 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat YL1 PF05764.8 EDO02056.1 - 0.013 15.0 9.2 0.02 14.5 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EDO02056.1 - 0.021 12.8 11.8 0.028 12.3 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 EDO02056.1 - 2.2 7.4 18.7 0.26 10.5 9.8 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EDO02056.1 - 2.8 5.8 14.3 3.9 5.3 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EDO02056.1 - 7.4 4.8 18.4 11 4.3 12.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Methyltransf_11 PF08241.7 EDO02057.1 - 3e-14 53.2 0.0 1.2e-13 51.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO02057.1 - 3.5e-12 46.1 0.0 4.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO02057.1 - 8.6e-10 38.1 0.0 1.9e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EDO02057.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02057.1 - 4.6e-08 33.4 0.0 1e-07 32.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO02057.1 - 1.4e-07 31.5 0.0 3.6e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02057.1 - 2.4e-06 28.0 0.0 6e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO02057.1 - 5.1e-06 26.7 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO02057.1 - 7e-05 22.2 0.0 0.00016 21.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 EDO02057.1 - 0.0031 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_5 PF01795.14 EDO02057.1 - 0.035 13.3 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Met_10 PF02475.11 EDO02057.1 - 0.061 12.8 0.0 0.096 12.2 0.0 1.3 1 1 0 1 1 1 0 Met-10+ like-protein mRNA_triPase PF02940.10 EDO02058.1 - 4.9e-55 186.5 3.1 4.9e-55 186.5 2.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 EDO02060.1 - 5.4e-42 139.7 15.5 7.4e-09 35.3 0.0 9.6 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDO02060.1 - 2.2e-17 63.1 0.1 4.2e-13 49.4 0.0 4.4 4 1 0 5 5 5 1 HEAT repeats HEAT PF02985.17 EDO02060.1 - 4.3e-08 32.5 2.0 2.2 8.5 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EDO02060.1 - 2.7e-06 27.7 2.0 0.00016 22.0 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat ERAP1_C PF11838.3 EDO02060.1 - 0.004 16.4 0.1 0.4 9.8 0.0 3.0 3 0 0 3 3 3 1 ERAP1-like C-terminal domain DUF1546 PF07571.8 EDO02060.1 - 0.06 13.4 0.5 6.5 6.9 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 EDO02060.1 - 0.33 11.5 3.3 3.8 8.2 0.0 4.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Transp_cyt_pur PF02133.10 EDO02061.1 - 4.3e-97 325.4 35.5 5.1e-97 325.2 24.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rad50_zn_hook PF04423.9 EDO02062.1 - 0.0053 16.2 0.9 6.6 6.2 0.4 3.4 3 0 0 3 3 3 2 Rad50 zinc hook motif YhfH PF14149.1 EDO02062.1 - 3.1 7.6 6.4 5.2 6.9 0.1 3.6 3 0 0 3 3 3 0 YhfH-like protein p450 PF00067.17 EDO02063.1 - 2.7e-71 240.4 0.0 3.1e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 EDO02064.1 - 2.4e-29 102.0 0.0 4.1e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDO02064.1 - 1.5e-27 95.6 0.0 2.5e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EDO02064.1 - 3.1e-23 81.3 0.1 5.5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_9 PF08021.6 EDO02064.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 EDO02064.1 - 0.0012 18.8 0.0 0.06 13.2 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain OpgC_C PF10129.4 EDO02064.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 OpgC protein Bac_rhamnosid PF05592.6 EDO02065.1 - 7.5e-40 136.6 0.0 1.3e-33 116.0 0.0 2.5 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EDO02065.1 - 1.8e-07 30.1 0.1 3.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EDO02065.1 - 0.00014 20.6 0.0 0.00023 20.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Cyclin_N PF00134.18 EDO02073.1 - 3.2e-05 23.4 0.6 0.032 13.8 0.0 3.4 3 0 0 3 3 3 2 Cyclin, N-terminal domain AAA_18 PF13238.1 EDO02073.1 - 0.013 15.8 0.1 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TFIIB PF00382.14 EDO02073.1 - 0.016 15.0 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat T2SE PF00437.15 EDO02073.1 - 0.03 13.2 0.1 0.03 13.2 0.1 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_17 PF13207.1 EDO02073.1 - 0.038 14.7 0.0 0.13 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDO02073.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pectinesterase PF01095.14 EDO02075.1 - 4.4e-49 166.6 10.8 5.7e-49 166.2 7.5 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.12 EDO02076.1 - 1.1e-44 152.6 10.6 1.4e-44 152.3 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glug PF07581.7 EDO02076.1 - 0.43 10.8 7.6 0.73 10.1 1.5 3.8 3 0 0 3 3 3 0 The GLUG motif Peptidase_M28 PF04389.12 EDO02077.1 - 9.3e-37 126.4 0.1 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Phage_gp49_66 PF13876.1 EDO02079.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family YwqJ-deaminase PF14431.1 EDO02080.1 - 0.015 15.1 1.0 7.7 6.3 0.0 3.1 3 0 0 3 3 3 0 YwqJ-like deaminase Cmc1 PF08583.5 EDO02080.1 - 0.026 14.3 1.2 0.079 12.7 0.9 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2874 PF11396.3 EDO02080.1 - 0.079 12.9 0.4 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) RRM_3 PF08777.6 EDO02080.1 - 0.11 12.3 5.7 0.13 12.1 1.5 2.6 3 0 0 3 3 3 0 RNA binding motif PQ-loop PF04193.9 EDO02081.1 - 1.7e-18 65.9 1.2 5.1e-12 45.1 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat Glyco_hydro_42M PF08532.5 EDO02082.1 - 0.0033 16.6 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Cep57_MT_bd PF06657.8 EDO02085.1 - 6.9e-19 67.5 3.5 6.9e-19 67.5 2.4 4.9 4 1 1 5 5 5 1 Centrosome microtubule-binding domain of Cep57 DUF948 PF06103.6 EDO02085.1 - 0.036 13.9 0.7 0.036 13.9 0.5 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EDO02085.1 - 0.09 11.9 21.0 0.11 11.7 2.7 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EDO02085.1 - 2.2 8.2 30.8 0.64 9.9 1.0 6.6 4 1 3 7 7 7 0 Flagella accessory protein C (FlaC) Prefoldin_3 PF13758.1 EDO02086.1 - 4.5e-33 112.9 3.2 1.1e-32 111.6 2.2 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EDO02086.1 - 2.2e-22 79.7 0.1 2.2e-22 79.7 0.1 5.3 6 1 0 6 6 6 1 Domain of unknown function (DUF3835) FliJ PF02050.11 EDO02086.1 - 0.022 14.7 3.3 0.25 11.3 0.2 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Prefoldin PF02996.12 EDO02086.1 - 0.03 13.9 2.3 0.69 9.5 0.3 2.6 2 0 0 2 2 2 0 Prefoldin subunit EAP30 PF04157.11 EDO02086.1 - 0.053 12.6 0.1 7.9 5.5 0.0 2.4 2 0 0 2 2 2 0 EAP30/Vps36 family Prefoldin_2 PF01920.15 EDO02086.1 - 0.27 11.0 8.7 0.28 10.9 1.5 3.0 3 0 0 3 3 3 0 Prefoldin subunit PS_Dcarbxylase PF02666.10 EDO02087.1 - 6.8e-54 182.2 0.0 8.5e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M20 PF01546.23 EDO02089.1 - 3e-29 101.9 0.0 4.3e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO02089.1 - 4.1e-12 45.8 0.0 1.4e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EDO02089.1 - 0.055 12.2 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Abhydrolase_5 PF12695.2 EDO02090.1 - 2.3e-05 24.2 0.0 6.7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO02090.1 - 0.002 18.0 0.0 0.018 14.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDO02090.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1748 PF08520.5 EDO02091.1 - 4e-37 125.6 0.1 4.7e-37 125.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 EDO02092.1 - 2.2e-168 559.3 4.8 3e-168 558.8 3.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EDO02092.1 - 7.4e-31 106.1 0.0 2.3e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EDO02092.1 - 0.00034 19.5 1.0 0.00083 18.3 0.4 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family YPEB PF14620.1 EDO02093.1 - 0.0076 15.2 1.2 0.01 14.8 0.8 1.2 1 0 0 1 1 1 1 YpeB sporulation DUF342 PF03961.8 EDO02093.1 - 3 6.1 7.8 0.23 9.8 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EDO02093.1 - 5.5 6.4 9.5 0.69 9.4 2.0 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EDO02093.1 - 7.4 6.1 14.3 8.2 5.9 8.9 1.7 1 1 0 1 1 1 0 IncA protein F-box PF00646.28 EDO02094.1 - 0.0034 17.0 4.8 0.017 14.7 0.1 3.2 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 EDO02094.1 - 0.086 12.5 2.8 0.46 10.2 0.4 2.6 2 0 0 2 2 2 0 F-box-like WD40 PF00400.27 EDO02096.1 - 5.8e-22 76.7 8.6 9.3e-09 34.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EDO02097.1 - 7.3e-17 61.1 0.0 1.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO02097.1 - 1.2e-07 32.6 0.0 1.8e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Spt5-NGN PF03439.8 EDO02098.1 - 1.1e-24 85.9 0.1 1.9e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EDO02098.1 - 3e-22 79.3 62.2 6.8e-16 58.8 35.6 4.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EDO02098.1 - 6.8e-22 77.8 12.1 6.8e-22 77.8 8.4 4.4 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EDO02098.1 - 1.1e-08 34.3 13.1 0.001 18.7 0.6 5.2 5 0 0 5 5 5 2 KOW motif DUF3506 PF12014.3 EDO02100.1 - 1.5e-53 180.2 0.0 2.9e-53 179.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EDO02100.1 - 9.2e-10 38.1 0.3 9.2e-10 38.1 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDO02100.1 - 2e-05 24.1 0.4 2e-05 24.1 0.3 1.9 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 EDO02100.1 - 0.033 14.5 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like_2 PF13013.1 EDO02100.1 - 0.074 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain gpUL132 PF11359.3 EDO02101.1 - 0.018 14.3 0.4 0.13 11.6 0.1 1.9 1 1 1 2 2 2 0 Glycoprotein UL132 Ribosomal_L18_c PF14204.1 EDO02102.1 - 0.012 16.1 0.4 2 9.0 0.0 2.8 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region ATC_hydrolase PF14196.1 EDO02102.1 - 0.033 14.5 2.8 4 7.8 0.0 2.3 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase AATase PF07247.7 EDO02104.1 - 2.1e-22 79.3 0.0 2.8e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EDO02104.1 - 5.2e-05 22.2 0.2 0.00053 18.9 0.2 2.1 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 EDO02104.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain FAST_1 PF06743.10 EDO02104.1 - 0.095 12.4 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Exonuc_VII_S PF02609.11 EDO02105.1 - 0.014 15.1 1.0 0.051 13.3 0.7 1.9 1 1 0 1 1 1 0 Exonuclease VII small subunit GCN5L1 PF06320.8 EDO02105.1 - 0.032 14.0 0.4 0.045 13.5 0.2 1.4 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Paralemmin PF03285.10 EDO02105.1 - 0.036 13.5 3.9 0.046 13.2 2.7 1.2 1 0 0 1 1 1 0 Paralemmin FliD_N PF02465.13 EDO02105.1 - 0.043 14.1 4.2 0.052 13.9 2.9 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus KIP1 PF07765.7 EDO02105.1 - 0.15 11.9 0.3 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 KIP1-like protein DUF4364 PF14277.1 EDO02105.1 - 0.15 11.6 0.8 0.18 11.4 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) HD_3 PF13023.1 EDO02105.1 - 0.18 11.5 1.8 0.2 11.3 1.3 1.1 1 0 0 1 1 1 0 HD domain Uds1 PF15456.1 EDO02105.1 - 0.21 11.5 4.7 0.23 11.4 3.3 1.1 1 0 0 1 1 1 0 Up-regulated During Septation ADIP PF11559.3 EDO02105.1 - 0.29 11.0 4.7 0.31 10.9 3.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 EDO02105.1 - 0.32 10.8 3.4 0.38 10.5 2.4 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.9 EDO02105.1 - 0.33 10.8 6.6 0.4 10.6 4.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EDO02105.1 - 0.36 10.4 4.5 0.41 10.2 3.1 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EDO02105.1 - 0.6 9.1 5.0 0.67 8.9 3.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 EDO02105.1 - 0.79 10.0 4.4 0.82 9.9 2.8 1.3 1 1 0 1 1 1 0 Striatin family Fmp27_WPPW PF10359.4 EDO02105.1 - 1.4 7.2 5.9 1.5 7.1 4.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HMG_box PF00505.14 EDO02108.1 - 4.9e-18 65.1 1.8 1.1e-17 64.0 1.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO02108.1 - 1.2e-14 54.3 1.8 2.6e-14 53.3 1.2 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EDO02108.1 - 4.1e-10 39.6 0.0 8.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDO02108.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IF-2B PF01008.12 EDO02109.1 - 7.2e-74 248.2 0.0 1.2e-73 247.5 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Prefoldin_3 PF13758.1 EDO02109.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Prefoldin subunit DAO PF01266.19 EDO02111.1 - 6.3e-26 91.1 0.2 1.3e-25 90.0 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO02111.1 - 0.0024 17.9 0.0 0.59 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO02111.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TB2_DP1_HVA22 PF03134.14 EDO02112.1 - 7.3e-10 38.4 0.5 1.2e-09 37.8 0.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NRDE PF05742.7 EDO02113.1 - 2e-46 158.5 0.0 3.4e-45 154.4 0.0 2.0 1 1 0 1 1 1 1 NRDE protein Gal4_dimer PF03902.8 EDO02113.1 - 0.076 12.9 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF2854 PF11016.3 EDO02114.1 - 0.084 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Cu_amine_oxid PF01179.15 EDO02115.1 - 4.3e-171 569.2 0.1 6.1e-171 568.6 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EDO02115.1 - 7.2e-23 80.5 0.5 2.5e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EDO02115.1 - 1e-14 54.3 0.1 1.8e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_65N PF03636.10 EDO02115.1 - 0.05 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Lipase_GDSL PF00657.17 EDO02116.1 - 3.1e-10 40.2 1.9 4.5e-10 39.7 1.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDO02116.1 - 9e-06 25.9 4.6 1.6e-05 25.0 3.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4549 PF15082.1 EDO02117.1 - 0.068 12.8 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) FadA PF09403.5 EDO02119.1 - 0.53 10.2 3.4 0.24 11.4 0.3 1.9 2 0 0 2 2 2 0 Adhesion protein FadA PAT1 PF09770.4 EDO02119.1 - 0.59 8.3 11.2 0.89 7.7 7.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tfb2 PF03849.9 EDO02120.1 - 7e-121 403.3 0.0 1.4e-120 402.3 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EDO02120.1 - 0.0002 21.0 0.1 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 4HBT PF03061.17 EDO02121.1 - 9.3e-09 35.3 0.1 1.5e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EDO02121.1 - 0.013 15.4 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Sugar_tr PF00083.19 EDO02122.1 - 2.2e-91 306.7 21.6 2.6e-64 217.4 5.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO02122.1 - 5.1e-18 64.9 17.0 1.8e-16 59.8 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EDO02122.1 - 0.0011 17.7 0.5 0.0023 16.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) DUF441 PF04284.8 EDO02122.1 - 0.12 12.2 4.1 0.048 13.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF441) UNC-93 PF05978.11 EDO02122.1 - 3.1 7.2 13.0 1.6 8.2 0.2 3.2 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 UvdE PF03851.9 EDO02123.1 - 6.8e-108 359.8 0.0 9.4e-108 359.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Adeno_terminal PF02459.10 EDO02123.1 - 0.28 9.3 1.2 0.51 8.4 0.8 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TRP PF06011.7 EDO02125.1 - 3.6e-130 434.4 15.7 5.9e-130 433.7 10.9 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDO02125.1 - 1.1e-37 129.2 6.7 2.5e-37 128.0 4.6 1.6 1 0 0 1 1 1 1 ML-like domain Kelch_3 PF13415.1 EDO02129.1 - 0.00039 20.5 10.7 0.00069 19.7 0.1 5.4 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EDO02129.1 - 0.065 12.7 2.7 0.37 10.3 0.1 3.2 3 0 0 3 3 3 0 Kelch motif ArsB PF02040.10 EDO02130.1 - 7e-15 54.9 19.7 6.9e-10 38.4 7.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF2244 PF10003.4 EDO02130.1 - 1.4 8.2 6.6 0.093 12.1 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) S-methyl_trans PF02574.11 EDO02132.1 - 1.1e-23 84.0 0.0 2.4e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 Homocysteine S-methyltransferase DnaJ PF00226.26 EDO02133.1 - 1.5e-21 75.8 1.1 2.6e-21 75.1 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EDO02133.1 - 0.023 14.7 0.5 0.035 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EDO02133.1 - 0.19 11.3 2.0 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EDO02133.1 - 4.7 7.4 7.9 1.6 8.9 2.8 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Macoilin PF09726.4 EDO02134.1 - 0.033 12.4 1.6 0.033 12.4 1.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Umbravirus_LDM PF04817.7 EDO02134.1 - 7.6 5.6 13.7 11 5.0 9.5 1.3 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family DUF1012 PF06241.7 EDO02135.1 - 0.1 12.1 1.7 1.4 8.4 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1012) Antimicrobial10 PF08105.6 EDO02135.1 - 0.16 11.6 0.7 0.31 10.6 0.5 1.5 1 0 0 1 1 1 0 Metchnikowin family Aldo_ket_red PF00248.16 EDO02138.1 - 1.6e-70 237.1 0.0 1.8e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EDO02138.1 - 0.012 15.4 0.9 0.66 9.9 0.0 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family LIP PF03583.9 EDO02139.1 - 0.025 13.7 0.2 0.025 13.7 0.1 1.0 1 0 0 1 1 1 0 Secretory lipase GATA-N PF05349.7 EDO02140.1 - 0.23 11.5 1.8 1.1 9.4 0.1 2.0 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal DUF3678 PF12435.3 EDO02140.1 - 3.8 7.1 5.2 0.39 10.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Methyltrn_RNA_3 PF02598.12 EDO02141.1 - 5.4e-76 255.7 0.0 6.5e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase PAP_assoc PF03828.14 EDO02143.1 - 1.3e-11 44.2 0.1 2.7e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDO02143.1 - 2.3e-07 31.0 0.0 6.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pex24p PF06398.6 EDO02144.1 - 1.5e-100 336.4 0.2 1.9e-100 336.1 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Yip1 PF04893.12 EDO02145.1 - 5.6e-09 35.7 11.6 8.1e-09 35.2 7.5 1.6 1 1 0 1 1 1 1 Yip1 domain Pam16 PF03656.8 EDO02146.1 - 4.2e-34 117.0 0.3 4.9e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 Pam16 AKAP2_C PF15304.1 EDO02146.1 - 0.012 15.2 0.2 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus CopK PF11525.3 EDO02146.1 - 0.074 12.6 0.1 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Copper resistance protein K TPD52 PF04201.10 EDO02146.1 - 0.2 11.3 0.1 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Tumour protein D52 family DpnD-PcfM PF14207.1 EDO02146.1 - 1.6 8.5 6.2 0.24 11.2 1.0 2.0 2 0 0 2 2 2 0 DpnD/PcfM-like protein Oxidored_q6 PF01058.17 EDO02147.1 - 0.075 12.6 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit adh_short_C2 PF13561.1 EDO02148.1 - 5.3e-20 72.2 0.0 8.6e-20 71.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO02148.1 - 3e-17 63.0 0.0 5.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO02148.1 - 2.1e-05 24.2 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain BBP1_C PF15272.1 EDO02149.1 - 0.017 14.6 1.1 0.04 13.4 0.7 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Striatin PF08232.7 EDO02149.1 - 0.019 15.2 4.7 0.26 11.6 1.4 2.2 2 0 0 2 2 2 0 Striatin family DivIVA PF05103.8 EDO02149.1 - 0.34 10.9 4.0 0.096 12.7 0.6 1.7 2 0 0 2 2 2 0 DivIVA protein Uds1 PF15456.1 EDO02149.1 - 0.48 10.4 8.2 0.36 10.8 2.2 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Herpes_UL6 PF01763.11 EDO02149.1 - 0.8 7.8 3.7 0.23 9.5 0.7 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like DivIC PF04977.10 EDO02149.1 - 1.2 8.6 7.8 0.062 12.7 1.4 1.7 2 0 0 2 2 2 0 Septum formation initiator KIAA1328 PF15369.1 EDO02149.1 - 1.8 8.2 10.1 6.7 6.4 6.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 RRM_1 PF00076.17 EDO02151.1 - 2.6e-07 30.1 0.1 5.4e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO02151.1 - 7.3e-06 25.8 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO02151.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Allexi_40kDa PF05549.6 EDO02151.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Amidase PF01425.16 EDO02152.1 - 2.9e-72 243.9 0.0 3.4e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF1772 PF08592.6 EDO02153.1 - 0.018 14.8 1.8 0.65 9.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Sulfate_transp PF00916.15 EDO02153.1 - 0.046 12.7 0.1 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Sulfate transporter family adh_short_C2 PF13561.1 EDO02154.1 - 1.7e-20 73.8 0.1 3.4e-20 72.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO02154.1 - 1.2e-17 64.3 0.7 1.7e-17 63.8 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO02154.1 - 1.2e-06 28.3 0.5 5e-06 26.2 0.3 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDO02154.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3079 PF11278.3 EDO02156.1 - 0.0005 19.5 0.1 0.00064 19.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3079) Peptidase_S21 PF00716.12 EDO02159.1 - 0.28 10.4 2.3 0.43 9.8 1.6 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF4526 PF15029.1 EDO02159.1 - 3.1 7.3 5.7 5.8 6.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) SVM_signal PF12113.3 EDO02161.1 - 0.086 12.6 1.4 0.12 12.2 0.9 1.2 1 0 0 1 1 1 0 SVM protein signal sequence GSDH PF07995.6 EDO02163.1 - 6.8e-05 22.1 0.0 0.00012 21.2 0.0 1.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Pox_RNA_pol PF03293.9 EDO02166.1 - 0.1 12.0 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit zf-CCHC_4 PF14392.1 EDO02169.1 - 0.047 13.3 2.3 0.94 9.2 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-RanBP PF00641.13 EDO02169.1 - 5.1 6.2 12.0 8.2 5.6 0.2 3.7 3 1 0 3 3 3 0 Zn-finger in Ran binding protein and others Exo_endo_phos_2 PF14529.1 EDO02170.1 - 2.1e-22 78.9 1.5 5.4e-22 77.6 1.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDO02170.1 - 1.9e-05 24.7 0.8 3.4e-05 23.9 0.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EDO02171.1 - 2.7e-15 56.8 0.0 5.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDO02171.1 - 0.0042 17.3 0.2 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Na_H_Exchanger PF00999.16 EDO02172.1 - 2.1e-70 237.1 47.3 2.9e-70 236.7 32.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pribosyltran PF00156.22 EDO02173.1 - 1.6e-08 34.3 0.1 1.4e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF2829 PF11195.3 EDO02173.1 - 0.098 13.1 0.1 0.8 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) 2-Hacid_dh_C PF02826.14 EDO02174.1 - 1.2e-16 60.3 0.0 4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO02174.1 - 0.0037 16.7 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 EDO02174.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC_tran PF00005.22 EDO02175.1 - 5.3e-47 159.5 0.1 4.2e-22 78.9 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EDO02175.1 - 3.3e-20 71.7 6.7 3.3e-20 71.7 4.7 4.1 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.1 EDO02175.1 - 1.6e-16 61.1 1.1 0.0021 18.0 0.0 5.0 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 EDO02175.1 - 3.3e-11 42.8 0.9 0.01 15.0 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDO02175.1 - 6.2e-09 36.7 0.1 0.0052 17.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDO02175.1 - 1.4e-06 28.4 0.0 0.11 12.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EDO02175.1 - 3.2e-06 26.8 0.2 0.12 12.0 0.2 2.9 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EDO02175.1 - 5e-06 26.6 3.2 0.0013 18.7 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EDO02175.1 - 5.9e-06 25.7 0.1 0.067 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EDO02175.1 - 1.1e-05 25.9 0.7 0.028 14.9 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_15 PF13175.1 EDO02175.1 - 1.8e-05 24.0 6.7 0.21 10.6 0.0 4.6 4 2 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.1 EDO02175.1 - 2.3e-05 24.7 2.5 0.31 11.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 EDO02175.1 - 2.5e-05 23.5 0.1 0.043 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDO02175.1 - 3.2e-05 23.8 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EDO02175.1 - 3.3e-05 23.3 0.1 0.19 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO02175.1 - 5.6e-05 23.0 0.1 0.49 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EDO02175.1 - 0.00017 21.7 0.1 0.84 9.8 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDO02175.1 - 0.00017 21.2 0.1 0.21 11.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EDO02175.1 - 0.00023 20.7 0.0 1.3 8.4 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain AAA_14 PF13173.1 EDO02175.1 - 0.00029 20.7 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EDO02175.1 - 0.00079 19.4 4.6 0.061 13.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 EDO02175.1 - 0.0009 18.1 1.7 0.47 9.1 0.0 2.9 3 0 0 3 3 3 2 ArgK protein AAA_23 PF13476.1 EDO02175.1 - 0.0013 19.0 20.3 0.036 14.4 0.0 4.9 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.17 EDO02175.1 - 0.0027 17.8 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EDO02175.1 - 0.0029 17.3 0.1 0.87 9.2 0.1 3.0 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.7 EDO02175.1 - 0.0049 15.9 1.7 0.26 10.3 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin SbcCD_C PF13558.1 EDO02175.1 - 0.011 15.6 0.2 6.7 6.6 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 EDO02175.1 - 0.012 15.1 0.9 2.7 7.3 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EDO02175.1 - 0.018 14.6 0.1 4 6.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDO02175.1 - 0.02 14.6 0.6 5.5 6.8 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_5 PF07728.9 EDO02175.1 - 0.029 14.1 0.6 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EDO02175.1 - 0.029 13.2 0.1 4.2 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 EDO02175.1 - 0.037 13.5 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EDO02175.1 - 0.058 12.8 0.1 9.7 5.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EDO02175.1 - 0.19 11.1 3.6 4.5 6.6 0.2 2.9 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain COG2 PF06148.6 EDO02175.1 - 0.51 10.2 5.4 0.33 10.8 0.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF87 PF01935.12 EDO02175.1 - 1.1 9.0 11.6 1.4 8.7 0.0 4.2 6 0 0 6 6 5 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EDO02175.1 - 2.5 7.8 14.8 4.4 7.1 0.3 3.7 3 1 0 3 3 2 0 Dynamin family Tubulin PF00091.20 EDO02176.1 - 1.3e-69 234.3 0.0 2.1e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO02176.1 - 1.2e-48 164.3 0.1 1.9e-48 163.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDO02176.1 - 1.7e-05 24.8 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EDO02176.1 - 0.005 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Arginosuc_synth PF00764.14 EDO02177.1 - 2e-154 514.3 0.0 2.3e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EDO02177.1 - 0.00068 19.2 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EDO02177.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EDO02177.1 - 0.023 13.2 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase CIA30 PF08547.7 EDO02178.1 - 3.7e-22 78.8 0.3 6e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 EDO02179.1 - 0.00022 21.1 7.4 0.00022 21.1 5.1 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDO02179.1 - 0.0013 18.4 6.9 0.0026 17.5 4.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDO02179.1 - 2.8 8.3 10.6 5.8 7.2 7.3 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF4499 PF14934.1 EDO02182.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) RNase_H2-Ydr279 PF09468.5 EDO02183.1 - 0.0023 17.1 9.0 0.0023 17.1 6.2 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF755 PF05501.6 EDO02183.1 - 0.015 15.3 15.7 0.017 15.2 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GAGA_bind PF06217.7 EDO02183.1 - 0.052 13.5 5.8 0.05 13.5 4.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family YL1 PF05764.8 EDO02183.1 - 0.062 12.9 13.6 0.072 12.6 9.4 1.0 1 0 0 1 1 1 0 YL1 nuclear protein DCP2 PF05026.8 EDO02183.1 - 0.065 13.1 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Dcp2, box A domain MRL1 PF13003.2 EDO02183.1 - 0.069 12.9 7.3 0.07 12.9 5.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 BLVR PF06375.6 EDO02183.1 - 0.12 12.2 21.8 0.15 11.8 15.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Rtf2 PF04641.7 EDO02183.1 - 0.21 10.7 12.1 0.26 10.4 8.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4604 PF15377.1 EDO02183.1 - 0.21 11.7 19.6 0.27 11.4 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Casc1 PF12366.3 EDO02183.1 - 0.35 10.3 7.2 0.35 10.3 5.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Peroxin-13_N PF04088.8 EDO02183.1 - 0.39 10.6 3.1 0.34 10.8 2.1 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Med19 PF10278.4 EDO02183.1 - 0.74 9.4 24.9 0.88 9.2 17.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Topoisom_I_N PF02919.10 EDO02183.1 - 1.8 7.7 12.1 2 7.6 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TSGP1 PF07771.6 EDO02183.1 - 2.5 7.9 14.3 3.6 7.5 9.9 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 OAD_gamma PF04277.8 EDO02183.1 - 3.2 8.1 5.5 3.9 7.9 3.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.5 EDO02183.1 - 4.2 7.1 16.9 5.2 6.8 11.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YqfQ PF14181.1 EDO02183.1 - 4.3 7.3 12.3 5.2 7.0 8.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein RNA_polI_A34 PF08208.6 EDO02183.1 - 6 6.4 26.2 6.7 6.3 18.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1168 PF06658.7 EDO02183.1 - 6.1 6.3 24.9 7.5 6.0 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FadA PF09403.5 EDO02184.1 - 0.077 13.0 2.5 2.9 7.9 0.3 2.2 2 0 0 2 2 2 0 Adhesion protein FadA L_lactis_ph-MCP PF06673.6 EDO02184.1 - 0.26 10.0 1.4 0.33 9.6 1.0 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein PhyH PF05721.8 EDO02185.1 - 7.4e-12 45.7 0.0 1.5e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 EDO02185.1 - 0.017 14.7 0.0 0.7 9.5 0.0 2.3 1 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Cupin_2 PF07883.6 EDO02185.1 - 0.063 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Melibiase PF02065.13 EDO02186.1 - 3.5e-13 49.0 0.0 6.6e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 EDO02186.1 - 7e-12 45.4 1.2 1.3e-11 44.5 0.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EDO02186.1 - 0.022 14.1 2.0 3.3 7.0 0.0 2.8 2 1 1 3 3 3 0 Cytolethal distending toxin A/C family Spherulin4 PF12138.3 EDO02188.1 - 9.7e-49 166.0 0.2 1.1e-48 165.8 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 DUF4161 PF13722.1 EDO02188.1 - 0.012 15.9 0.5 0.02 15.1 0.4 1.3 1 0 0 1 1 1 0 C-terminal domain on CstA (DUF4161) UPF0167 PF03691.9 EDO02188.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) C1_1 PF00130.17 EDO02191.1 - 0.0013 18.3 4.6 0.0025 17.5 3.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 EDO02191.1 - 0.021 14.7 1.3 0.038 13.8 0.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EDO02191.1 - 0.055 13.3 3.8 0.11 12.3 2.6 1.5 1 0 0 1 1 1 0 IBR domain zf-CHCC PF10276.4 EDO02191.1 - 4.3 7.2 6.9 7.3 6.5 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger domain Methyltransf_11 PF08241.7 EDO02192.1 - 1.7e-13 50.8 0.0 3.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO02192.1 - 1.8e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02192.1 - 1.9e-09 37.8 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO02192.1 - 4.5e-09 36.0 0.0 7.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02192.1 - 7.3e-08 32.9 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO02192.1 - 8.1e-08 32.5 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO02192.1 - 6.5e-07 28.6 0.0 9.9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EDO02192.1 - 0.00062 19.7 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EDO02192.1 - 0.051 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Myb_DNA-bind_6 PF13921.1 EDO02193.1 - 0.00086 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO02193.1 - 0.04 13.9 0.7 0.12 12.4 0.4 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 EDO02193.1 - 0.41 10.9 9.2 1.5 9.1 3.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_6 PF12697.2 EDO02194.1 - 3.5e-18 66.3 0.9 2.2e-17 63.6 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO02194.1 - 4.3e-10 39.5 0.0 2.6e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO02194.1 - 1.4e-08 34.5 0.1 2.2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDO02194.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 EDO02194.1 - 0.13 11.4 0.1 0.54 9.4 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF621 PF04789.10 EDO02194.1 - 0.18 10.7 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) DUF3445 PF11927.3 EDO02195.1 - 1.6e-76 257.0 0.0 2e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3195 PF11424.3 EDO02195.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) ADH_zinc_N PF00107.21 EDO02199.1 - 1.1e-12 47.5 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO02199.1 - 4.4e-07 29.6 0.7 1.1e-06 28.3 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-H2C2_2 PF13465.1 EDO02200.1 - 3.8e-14 52.1 8.2 4.8e-08 32.9 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDO02200.1 - 1.9e-12 46.7 11.6 4.9e-06 26.5 1.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO02200.1 - 3.1e-11 42.7 12.0 2.3e-05 24.4 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO02200.1 - 5.7e-07 29.4 2.1 0.069 13.3 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO02200.1 - 3.6e-05 23.7 1.4 0.015 15.4 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EDO02200.1 - 0.11 12.6 1.6 0.23 11.5 1.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L11_N PF03946.9 EDO02200.1 - 0.29 10.6 1.7 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain zf-BED PF02892.10 EDO02200.1 - 0.55 10.0 4.7 1.2 8.8 0.7 2.5 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 EDO02200.1 - 0.97 9.5 3.1 5.4 7.1 2.1 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EDO02200.1 - 6.3 6.8 11.1 15 5.6 0.3 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Cation_efflux PF01545.16 EDO02201.1 - 1.9e-30 105.9 10.6 2.6e-30 105.4 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family DMRL_synthase PF00885.14 EDO02203.1 - 2e-41 141.0 0.0 3.4e-24 85.1 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase DUF3074 PF11274.3 EDO02204.1 - 1.1e-30 106.6 1.6 1.4e-30 106.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Formyl_trans_N PF00551.14 EDO02205.1 - 3.3e-39 134.2 0.1 4e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase FimP PF09766.4 EDO02206.1 - 1.2e-27 96.9 9.0 1.5e-27 96.6 6.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 EDO02206.1 - 0.013 15.2 0.3 0.013 15.2 0.2 2.8 2 1 0 2 2 2 0 K-box region DUF4200 PF13863.1 EDO02206.1 - 0.59 10.0 11.1 0.59 10.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.6 EDO02206.1 - 0.68 9.8 4.1 8.2 6.3 0.2 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pinin_SDK_memA PF04696.8 EDO02206.1 - 1 8.9 8.0 2.7 7.5 1.7 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region VSP PF03302.8 EDO02207.1 - 0.062 11.9 0.2 0.098 11.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein FYRC PF05965.9 EDO02207.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Aldolase_II PF00596.16 EDO02208.1 - 1.9e-42 144.9 0.0 2.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 EDO02209.1 - 9e-160 531.2 19.6 1.2e-159 530.9 13.6 1.1 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.8 EDO02209.1 - 0.0072 16.6 0.5 0.0072 16.6 0.3 3.4 5 0 0 5 5 5 1 Oxaloacetate decarboxylase, gamma chain PHO4 PF01384.15 EDO02210.1 - 4.4e-121 403.5 19.3 5.1e-121 403.3 13.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Pkinase PF00069.20 EDO02211.1 - 2.7e-50 170.9 0.7 7e-44 149.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02211.1 - 8.2e-27 93.9 0.2 1.5e-24 86.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO02211.1 - 2.2e-12 46.5 0.0 3.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EDO02211.1 - 8e-12 44.9 0.2 1.4e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EDO02211.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EDO02212.1 - 8.9e-55 184.1 4.5 1.3e-54 183.6 3.1 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Methyltrans_Mon PF14314.1 EDO02212.1 - 0.00014 19.8 0.7 0.00018 19.5 0.5 1.1 1 0 0 1 1 1 1 Virus-capping methyltransferase Transglut_i_TM PF14400.1 EDO02212.1 - 0.008 15.7 2.0 0.008 15.7 1.4 2.1 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices DUF3347 PF11827.3 EDO02212.1 - 0.48 10.4 6.6 0.15 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Barstar PF01337.13 EDO02212.1 - 0.49 10.2 2.2 0.54 10.1 0.3 2.0 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Mis12 PF05859.7 EDO02212.1 - 0.61 9.8 10.4 0.2 11.4 2.3 2.3 2 0 0 2 2 2 0 Mis12 protein DUF3391 PF11871.3 EDO02212.1 - 0.73 10.0 9.9 2.4 8.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) IncA PF04156.9 EDO02212.1 - 0.84 9.1 13.2 0.045 13.3 4.8 1.8 2 0 0 2 2 2 0 IncA protein DUF4200 PF13863.1 EDO02212.1 - 1.7 8.6 21.6 0.19 11.7 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF848 PF05852.6 EDO02212.1 - 1.7 8.4 12.8 0.21 11.4 3.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin PF00261.15 EDO02212.1 - 2.3 7.2 23.4 0.015 14.4 7.4 2.2 1 1 0 1 1 1 0 Tropomyosin Cauli_AT PF03233.8 EDO02212.1 - 2.5 7.7 5.3 0.7 9.5 1.4 1.6 2 0 0 2 2 2 0 Aphid transmission protein DUF2681 PF10883.3 EDO02212.1 - 3 8.1 10.6 0.19 11.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Med21 PF11221.3 EDO02212.1 - 4 7.3 16.7 0.45 10.4 7.5 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Mnd1 PF03962.10 EDO02212.1 - 4.5 6.8 14.5 0.71 9.5 3.2 2.1 2 0 0 2 2 2 0 Mnd1 family VIT1 PF01988.14 EDO02212.1 - 5.1 6.5 7.3 0.29 10.6 0.6 1.9 2 0 0 2 2 2 0 VIT family DUF3256 PF11644.3 EDO02213.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) SBDS PF01172.13 EDO02214.1 - 8.2e-25 86.4 0.6 9.2e-25 86.2 0.4 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ABC2_membrane_3 PF12698.2 EDO02215.1 - 0.38 9.7 4.4 0.46 9.4 3.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein APH PF01636.18 EDO02218.1 - 2.3e-08 34.0 0.0 2.9e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3533 PF12051.3 EDO02219.1 - 5.4e-71 239.3 13.6 6.7e-71 239.0 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2992 PF11208.3 EDO02219.1 - 0.046 13.6 0.1 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) Translin PF01997.11 EDO02221.1 - 8.8e-59 198.4 0.0 1.1e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Translin family Mannosyl_trans PF05007.8 EDO02222.1 - 3.7e-13 49.7 2.0 7.7e-13 48.6 0.1 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EDO02222.1 - 1.8e-10 40.2 0.5 2.5e-10 39.7 0.4 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EDO02222.1 - 7.5e-06 25.6 12.3 1.1e-05 25.0 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) TspO_MBR PF03073.10 EDO02222.1 - 0.011 15.2 0.7 0.033 13.7 0.5 1.8 1 0 0 1 1 1 0 TspO/MBR family Mannosyl_trans PF05007.8 EDO02223.1 - 1.1e-28 100.6 11.7 1.2e-28 100.4 8.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF3007 PF11460.3 EDO02223.1 - 0.074 13.1 1.8 0.1 12.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) F-box-like PF12937.2 EDO02224.1 - 0.0014 18.3 0.0 0.012 15.3 0.0 2.6 2 1 0 2 2 2 1 F-box-like DUF1769 PF08588.5 EDO02226.1 - 4e-30 103.5 0.5 8e-30 102.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Kelch_4 PF13418.1 EDO02227.1 - 8.3e-18 63.9 2.5 1.2e-06 28.1 0.0 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO02227.1 - 2.5e-17 62.5 3.2 3.6e-09 36.5 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO02227.1 - 8e-11 41.6 5.4 0.00059 19.7 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EDO02227.1 - 4.9e-09 35.9 4.9 0.069 13.3 0.9 5.3 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EDO02227.1 - 7.1e-08 31.8 0.1 0.32 10.5 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EDO02227.1 - 2.9e-06 26.7 0.8 0.033 13.9 0.0 4.5 4 1 0 4 4 4 2 Kelch motif BTB PF00651.26 EDO02227.1 - 0.0015 18.4 0.0 0.049 13.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.16 EDO02228.1 - 1.4e-33 115.2 0.0 1.9e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO02228.1 - 7.4e-14 51.5 0.0 9.6e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDO02228.1 - 7.9e-11 41.4 0.0 1.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 EDO02229.1 - 1.5e-15 56.8 15.0 2e-15 56.3 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO02229.1 - 9.3e-08 31.0 4.1 1.4e-07 30.4 2.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter P_proprotein PF01483.15 EDO02229.1 - 0.057 13.2 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Proprotein convertase P-domain Neurensin PF14927.1 EDO02229.1 - 0.16 11.3 0.7 1 8.7 0.1 2.4 2 0 0 2 2 2 0 Neurensin Mpv17_PMP22 PF04117.7 EDO02230.1 - 2.2e-24 84.8 0.2 4.5e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2949 PF11165.3 EDO02230.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) IF4E PF01652.13 EDO02231.1 - 1.2e-61 207.0 0.2 1.5e-61 206.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 EDO02232.1 - 1.5e-46 158.6 0.0 2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO02232.1 - 1.2e-11 45.4 0.0 2.6e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 EDO02233.1 - 8.7e-29 99.3 1.6 1.1e-28 99.0 1.1 1.1 1 0 0 1 1 1 1 BolA-like protein FSH1 PF03959.8 EDO02234.1 - 3.2e-28 98.6 0.0 3.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDO02234.1 - 0.0039 17.1 0.7 0.087 12.6 0.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO02234.1 - 0.028 13.8 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDO02234.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Porph_ging PF09697.5 EDO02235.1 - 0.42 10.7 1.9 0.57 10.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) DUF4207 PF13904.1 EDO02238.1 - 0.45 9.8 17.4 0.54 9.5 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) KAR9 PF08580.5 EDO02238.1 - 0.64 8.2 15.1 0.64 8.2 10.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MAP65_ASE1 PF03999.7 EDO02238.1 - 3.2 6.2 8.5 3 6.3 5.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4551 PF15087.1 EDO02238.1 - 8.4 4.6 9.8 9.5 4.4 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) tRNA-synt_2 PF00152.15 EDO02239.1 - 5.5e-44 150.3 0.0 1.9e-43 148.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO02239.1 - 0.00093 19.0 0.0 0.006 16.4 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain ANTH PF07651.11 EDO02240.1 - 3.5e-18 65.3 1.2 7e-14 51.2 0.0 2.4 1 1 1 2 2 2 2 ANTH domain MAT1 PF06391.8 EDO02241.1 - 1e-34 119.9 7.2 1.4e-34 119.4 5.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EDO02241.1 - 4.4e-05 23.0 5.0 9.8e-05 21.9 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO02241.1 - 0.0029 17.6 6.2 0.0061 16.5 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO02241.1 - 0.0073 15.9 5.9 0.013 15.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO02241.1 - 0.19 11.6 7.5 0.39 10.5 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EDO02241.1 - 0.37 10.5 9.2 1.6 8.5 6.5 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EDO02241.1 - 0.68 9.5 6.9 0.84 9.2 1.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.11 EDO02242.1 - 1.5e-16 60.6 0.6 3e-15 56.5 0.1 2.3 2 0 0 2 2 2 1 CS domain Ribophorin_II PF05817.9 EDO02243.1 - 3.7e-22 78.3 0.1 4.6e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2256 PF10013.4 EDO02245.1 - 0.002 17.8 2.2 0.0049 16.6 1.5 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) TauD PF02668.11 EDO02246.1 - 5.7e-59 199.8 0.0 6.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3336 PF11815.3 EDO02247.1 - 1.6e-38 131.4 1.7 3.5e-38 130.3 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO02247.1 - 3.7e-23 82.5 0.1 1.1e-22 80.9 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase NAPRTase PF04095.11 EDO02248.1 - 2e-55 187.7 0.4 9e-31 107.0 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Tyrosinase PF00264.15 EDO02249.1 - 2.1e-52 178.5 1.2 2.1e-52 178.5 0.8 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Amidohydro_2 PF04909.9 EDO02250.1 - 1.2e-42 146.4 0.2 1.4e-42 146.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF3716 PF12511.3 EDO02252.1 - 0.086 12.4 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) FAD_binding_3 PF01494.14 EDO02253.1 - 1.7e-18 66.7 1.4 3.2e-17 62.6 0.9 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDO02253.1 - 4.2e-08 32.4 0.5 3e-07 29.6 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO02253.1 - 3.1e-07 30.3 0.6 6.8e-07 29.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO02253.1 - 7e-05 22.7 0.3 0.00015 21.7 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO02253.1 - 0.00024 20.1 3.9 0.00043 19.2 2.7 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDO02253.1 - 0.0009 18.4 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO02253.1 - 0.0011 19.3 0.6 0.0011 19.3 0.4 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO02253.1 - 0.0011 17.9 1.5 0.0016 17.3 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EDO02253.1 - 0.0016 17.3 0.1 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EDO02253.1 - 0.0032 17.0 0.1 0.0065 16.0 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EDO02253.1 - 0.005 15.9 0.3 0.26 10.3 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EDO02253.1 - 0.023 13.1 1.2 0.039 12.4 0.8 1.4 1 0 0 1 1 1 0 HI0933-like protein Rossmann-like PF10727.4 EDO02253.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 EDO02253.1 - 1.1 8.8 3.7 0.38 10.3 0.6 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EDO02254.1 - 2.2e-16 59.5 1.5 3.6e-16 58.8 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO02254.1 - 4.5e-05 23.2 9.1 0.0001 22.0 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Complex1_LYR_1 PF13232.1 EDO02256.1 - 0.0021 18.2 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDO02256.1 - 0.023 14.4 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF2663 PF10864.3 EDO02256.1 - 0.043 14.0 0.9 0.082 13.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) UQ_con PF00179.21 EDO02257.1 - 1.5e-18 66.6 0.0 1.6e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO02257.1 - 0.0055 16.5 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 EDO02258.1 - 2.9e-40 137.4 8.2 6.9e-40 136.2 0.5 3.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDO02258.1 - 1.7e-06 27.4 0.9 0.00021 20.7 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Band_7 PF01145.20 EDO02259.1 - 5.1e-31 107.9 0.5 1.1e-30 106.8 0.3 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EDO02259.1 - 0.0086 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family CCDC84 PF14968.1 EDO02260.1 - 0.00016 21.3 0.3 0.0002 20.9 0.2 1.3 1 1 0 1 1 1 1 Coiled coil protein 84 zf-U1 PF06220.7 EDO02260.1 - 0.00077 18.9 0.8 0.0012 18.3 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger Rxt3 PF08642.5 EDO02260.1 - 0.0043 17.2 1.1 0.0057 16.8 0.1 1.7 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Rubrerythrin PF02915.12 EDO02260.1 - 7.3 6.9 7.6 13 6.1 0.2 2.5 3 0 0 3 3 3 0 Rubrerythrin Peptidase_S49_N PF08496.5 EDO02261.1 - 0.098 12.4 4.4 0.22 11.3 3.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Aldo_ket_red PF00248.16 EDO02262.1 - 2.9e-46 157.5 0.0 3.9e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DAHP_synth_1 PF00793.15 EDO02263.1 - 2.8e-100 334.5 0.1 3.2e-100 334.2 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MIB_HERC2 PF06701.8 EDO02265.1 - 0.047 13.6 0.4 0.06 13.3 0.3 1.2 1 0 0 1 1 1 0 Mib_herc2 Oxidored-like PF09791.4 EDO02267.1 - 5.2e-26 89.8 3.7 9.1e-26 89.0 2.6 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.6 EDO02268.1 - 2.2e-34 117.1 0.0 2.4e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Av_adeno_fibre PF06536.6 EDO02268.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Avian adenovirus fibre LRR_4 PF12799.2 EDO02269.1 - 2.6e-42 141.7 46.3 1.4e-06 27.7 1.8 10.7 5 2 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO02269.1 - 2.8e-34 116.6 41.4 1.4e-05 24.7 1.4 8.2 4 2 5 10 10 10 9 Leucine rich repeat LRR_1 PF00560.28 EDO02269.1 - 1.1e-19 67.3 50.7 0.059 13.4 0.1 16.5 16 1 0 16 16 16 8 Leucine Rich Repeat LRR_7 PF13504.1 EDO02269.1 - 1e-14 52.0 39.2 0.041 14.0 0.1 15.4 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 EDO02269.1 - 3.4e-07 29.6 40.7 0.016 15.2 1.2 12.7 16 0 0 16 16 16 4 Leucine Rich repeat LRR_9 PF14580.1 EDO02269.1 - 0.31 10.5 13.6 2.6 7.5 0.1 4.5 3 1 2 5 5 5 0 Leucine-rich repeat GerE PF00196.14 EDO02270.1 - 0.057 12.7 1.5 0.29 10.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Med9 PF07544.8 EDO02270.1 - 3.6 7.3 9.5 0.088 12.5 0.9 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.16 EDO02270.1 - 4.2 7.4 11.8 0.068 13.1 1.8 2.7 2 1 1 3 3 3 0 bZIP transcription factor IncA PF04156.9 EDO02270.1 - 5.6 6.5 16.0 0.029 13.9 2.5 2.2 1 1 1 2 2 2 0 IncA protein KAP PF05804.7 EDO02271.1 - 7.7e-05 20.8 0.3 0.032 12.1 0.0 2.2 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EDO02271.1 - 0.031 13.3 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H RIX1 PF08167.7 EDO02271.1 - 0.046 13.3 0.4 0.25 10.9 0.2 2.2 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis BH4 PF02180.12 EDO02276.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Methyltransf_16 PF10294.4 EDO02278.1 - 4.8e-45 153.1 0.1 6.6e-45 152.6 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDO02278.1 - 0.019 15.5 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EDO02278.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EDO02278.1 - 0.058 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ABC_membrane PF00664.18 EDO02280.1 - 8.8e-89 297.5 37.9 2.5e-48 164.8 8.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO02280.1 - 2.1e-34 118.7 1.3 1.6e-27 96.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO02280.1 - 8.4e-07 28.4 8.4 0.0014 17.9 2.1 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO02280.1 - 1.1e-06 28.8 1.0 0.00079 19.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO02280.1 - 1.5e-06 27.4 0.1 0.0067 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDO02280.1 - 2.1e-06 27.1 3.3 0.00043 19.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO02280.1 - 4e-06 27.0 0.4 0.034 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EDO02280.1 - 1.4e-05 25.8 0.7 0.0063 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EDO02280.1 - 0.00035 19.2 0.0 0.055 12.0 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 EDO02280.1 - 0.00042 20.3 2.9 0.35 10.8 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 EDO02280.1 - 0.00076 19.7 1.0 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO02280.1 - 0.0011 18.3 1.2 1.1 8.6 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EDO02280.1 - 0.0061 16.1 0.7 1.8 8.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EDO02280.1 - 0.0066 16.3 0.1 0.92 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EDO02280.1 - 0.0079 15.7 0.4 1.9 7.9 0.1 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EDO02280.1 - 0.0081 15.6 1.0 0.99 8.7 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 EDO02280.1 - 0.01 15.6 0.1 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDO02280.1 - 0.02 13.9 0.1 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EDO02280.1 - 0.021 15.1 0.1 0.021 15.1 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.9 EDO02280.1 - 0.05 13.3 1.0 10 5.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EDO02280.1 - 0.074 13.2 0.9 6.1 7.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDO02280.1 - 0.086 12.7 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EDO02280.1 - 0.1 12.1 0.5 4.5 6.7 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family zf-LITAF-like PF10601.4 EDO02280.1 - 0.56 10.0 4.8 1.5 8.6 0.0 3.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain ABC_tran PF00005.22 EDO02281.1 - 1.3e-11 44.9 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EDO02281.1 - 0.00031 20.0 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EDO02281.1 - 0.0074 16.1 0.6 0.053 13.4 0.4 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EDO02281.1 - 0.015 13.9 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_21 PF13304.1 EDO02281.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 EDO02282.1 - 9.6 5.1 1.6 21 4.0 1.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF3676 PF12429.3 EDO02283.1 - 0.096 12.2 1.7 0.095 12.2 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Inhibitor_I67 PF11405.3 EDO02285.1 - 0.046 13.7 2.4 0.057 13.4 1.7 1.1 1 0 0 1 1 1 0 Bromelain inhibitor VI DltD_M PF04918.7 EDO02286.1 - 0.014 15.5 0.0 0.014 15.5 0.0 1.0 1 0 0 1 1 1 0 DltD central region Fungal_trans_2 PF11951.3 EDO02287.1 - 2.3e-06 26.4 0.1 6.6e-06 24.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain KAR9 PF08580.5 EDO02288.1 - 1.8e-132 442.9 6.5 1.8e-132 442.9 4.5 1.5 2 0 0 2 2 2 1 Yeast cortical protein KAR9 TBPIP PF07106.8 EDO02288.1 - 0.0011 18.5 1.0 2.2 7.8 0.0 3.8 4 0 0 4 4 4 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Erp_C PF06780.6 EDO02288.1 - 0.075 12.8 6.5 4.4 7.1 0.3 3.3 3 0 0 3 3 3 0 Erp protein C-terminus DUF4047 PF13256.1 EDO02288.1 - 0.45 10.4 2.7 3.6 7.5 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Spectrin PF00435.16 EDO02288.1 - 0.5 10.6 7.8 21 5.4 0.0 3.7 3 0 0 3 3 3 0 Spectrin repeat DUF2203 PF09969.4 EDO02288.1 - 0.75 10.0 2.5 6.7 6.9 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.20 EDO02288.1 - 1.2 9.3 8.1 32 4.7 0.0 4.2 4 0 0 4 4 4 0 Syntaxin Laminin_II PF06009.7 EDO02288.1 - 1.5 8.5 8.7 3 7.5 0.3 3.9 3 1 2 5 5 5 0 Laminin Domain II DUF972 PF06156.8 EDO02288.1 - 3.1 8.1 5.7 67 3.9 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) FMN_dh PF01070.13 EDO02289.1 - 6.1e-104 347.6 0.0 7.5e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDO02289.1 - 4.7e-16 58.3 0.0 1.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDO02289.1 - 7.2e-07 28.4 0.1 7.2e-07 28.4 0.1 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDO02289.1 - 4.4e-05 22.5 0.3 0.00018 20.5 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF4573 PF15140.1 EDO02289.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) DHO_dh PF01180.16 EDO02289.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EDO02289.1 - 0.016 14.4 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 EDO02289.1 - 0.029 13.5 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Cupin_1 PF00190.17 EDO02290.1 - 0.0097 15.3 0.1 0.07 12.5 0.0 2.0 1 1 1 2 2 2 1 Cupin DUF1414 PF07208.6 EDO02290.1 - 0.072 12.8 0.5 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Actin PF00022.14 EDO02291.1 - 9.6e-102 340.3 0.0 1.1e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Actin GCIP PF13324.1 EDO02292.1 - 5.6e-08 32.3 5.4 4.3e-07 29.4 1.2 2.3 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting BUD22 PF09073.5 EDO02292.1 - 0.046 12.7 4.3 0.051 12.6 3.0 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EDO02292.1 - 0.056 11.4 5.8 0.072 11.1 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 EDO02292.1 - 0.25 11.3 2.7 0.38 10.7 1.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.4 EDO02292.1 - 0.33 9.6 15.5 0.47 9.1 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EDO02292.1 - 0.5 9.9 9.0 0.46 10.0 5.4 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 EDO02292.1 - 3.7 6.7 6.5 5 6.2 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EDO02292.1 - 5.1 6.5 10.8 8.5 5.8 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin MFS_1 PF07690.11 EDO02293.1 - 6.8e-34 117.1 6.5 8.4e-34 116.8 4.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_16 PF13432.1 EDO02294.1 - 1.6e-06 28.5 1.7 0.0039 17.8 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02294.1 - 8e-06 26.0 4.8 0.046 14.3 0.1 5.9 6 2 1 7 7 7 1 Tetratricopeptide repeat Suf PF05843.9 EDO02294.1 - 5e-05 23.1 5.8 0.0044 16.7 0.1 3.1 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EDO02294.1 - 0.00061 20.0 0.0 2 8.8 0.0 3.8 1 1 4 5 5 5 1 Tetratricopeptide repeat Macoilin PF09726.4 EDO02295.1 - 0.43 8.7 14.3 0.59 8.3 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein IL28A PF15177.1 EDO02296.1 - 0.022 14.2 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Interleukin-28A DUF900 PF05990.7 EDO02297.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cyto_heme_lyase PF01265.12 EDO02298.1 - 1.9e-78 263.6 0.1 2.5e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 EDO02299.1 - 1.4e-22 79.9 0.0 8.2e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EDO02299.1 - 0.0024 17.6 2.1 0.03 14.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family P_C PF06640.6 EDO02300.1 - 0.64 9.9 3.5 0.74 9.7 2.4 1.0 1 0 0 1 1 1 0 P protein C-terminus DUF3602 PF12223.3 EDO02300.1 - 0.9 9.9 4.7 3.3 8.1 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) NST1 PF13945.1 EDO02301.1 - 0.059 13.4 1.3 0.14 12.1 0.9 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2215 PF10225.4 EDO02303.1 - 1.1 8.5 2.3 3.2 7.1 1.6 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) p450 PF00067.17 EDO02304.1 - 9.1e-78 261.8 0.0 2.1e-76 257.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EDO02306.1 - 2.2e-133 445.0 0.6 2.6e-133 444.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_cyclohydro2 PF00925.15 EDO02306.1 - 0.0049 16.1 0.0 0.0088 15.2 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II LuxC PF05893.9 EDO02306.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pyrophosphatase PF00719.14 EDO02307.1 - 1.6e-50 170.5 0.2 2.1e-50 170.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EDO02308.1 - 3.4e-05 23.7 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 EDO02309.1 - 7.8e-17 60.7 0.4 7.8e-17 60.7 0.3 2.9 4 0 0 4 4 4 1 Sec20 DUF3545 PF12065.3 EDO02309.1 - 0.048 13.4 0.4 0.048 13.4 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3545) 2TM PF13239.1 EDO02309.1 - 0.3 11.1 2.3 0.57 10.2 1.6 1.4 1 0 0 1 1 1 0 2TM domain Chitin_bind_1 PF00187.14 EDO02310.1 - 0.037 14.0 22.0 0.1 12.6 14.2 2.5 1 1 1 2 2 2 0 Chitin recognition protein Dus PF01207.12 EDO02312.1 - 8.5e-42 143.0 0.5 2.3e-41 141.6 0.3 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Baculo_ODV-E27 PF05314.6 EDO02312.1 - 0.013 14.5 0.2 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 TMP-TENI PF02581.12 EDO02312.1 - 0.039 13.0 1.9 2.2 7.3 0.0 2.6 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI His_Phos_2 PF00328.17 EDO02314.1 - 4.7e-24 85.3 0.0 6.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.7 EDO02318.1 - 1.2e-14 53.9 1.5 1.6e-12 47.1 1.1 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO02318.1 - 2.3e-09 36.8 1.4 1.3e-08 34.4 0.7 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO02318.1 - 0.059 14.2 0.3 0.11 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FMN_dh PF01070.13 EDO02319.1 - 2.9e-124 414.5 0.0 3.3e-124 414.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EDO02319.1 - 6.1e-06 25.4 0.4 0.06 12.4 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EDO02319.1 - 2.9e-05 23.3 0.1 4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EDO02319.1 - 0.00018 20.5 0.2 0.00035 19.6 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDO02319.1 - 0.00057 18.8 1.1 0.0051 15.7 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EDO02319.1 - 0.0011 18.2 0.4 0.041 13.1 0.1 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EDO02319.1 - 0.019 13.9 0.4 0.27 10.1 0.1 2.3 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase IGPS PF00218.16 EDO02319.1 - 0.078 12.0 0.2 0.37 9.7 0.2 1.9 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase NAD_binding_8 PF13450.1 EDO02320.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Kinesin PF00225.18 EDO02323.1 - 1.3e-95 319.9 0.0 2.4e-95 319.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DivIVA PF05103.8 EDO02323.1 - 8.4 6.4 11.8 1.8 8.6 0.1 2.8 2 1 1 3 3 3 0 DivIVA protein Stk19 PF10494.4 EDO02324.1 - 6.2e-85 284.5 0.0 8.6e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 His_Phos_1 PF00300.17 EDO02325.1 - 4.4e-09 36.6 0.0 6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DAGAT PF03982.8 EDO02328.1 - 1.4e-84 283.3 0.0 1.8e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Protocadherin PF08374.6 EDO02328.1 - 0.091 12.3 4.4 0.16 11.6 3.1 1.3 1 0 0 1 1 1 0 Protocadherin p450 PF00067.17 EDO02329.1 - 4.8e-77 259.4 0.0 6.1e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.15 EDO02330.1 - 2.3e-60 203.7 16.9 3e-60 203.4 11.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EDO02330.1 - 0.024 14.4 0.4 0.07 12.9 0.3 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF883 PF05957.8 EDO02330.1 - 0.043 14.1 3.5 0.31 11.4 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF373 PF04123.8 EDO02330.1 - 0.2 10.6 2.2 0.31 10.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MT0933_antitox PF14013.1 EDO02330.1 - 1.3 9.1 3.5 1.1 9.4 1.3 1.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein SET PF00856.23 EDO02331.1 - 3.6e-11 43.6 0.1 2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_2 PF07719.12 EDO02331.1 - 2.9e-07 29.8 0.1 0.25 11.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02331.1 - 9.1e-06 25.0 0.1 0.28 10.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO02331.1 - 0.00012 22.2 0.4 0.19 12.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02331.1 - 0.00017 21.1 0.4 0.89 9.2 0.1 3.4 2 1 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 EDO02331.1 - 0.0017 18.9 0.0 23 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO02331.1 - 0.057 13.3 0.6 4.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02331.1 - 0.085 13.5 0.1 54 4.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO02331.1 - 0.12 12.5 0.1 0.88 9.7 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EDO02331.1 - 0.17 11.7 0.7 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex2_Pex12 PF04757.9 EDO02332.1 - 1.4e-42 145.7 11.1 1.8e-42 145.3 7.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EDO02332.1 - 1.9e-12 46.7 7.6 3e-12 46.1 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO02332.1 - 2e-11 43.6 7.7 3.2e-11 43.0 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO02332.1 - 7e-11 41.6 4.5 1.1e-10 40.9 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO02332.1 - 3.8e-10 39.2 4.9 6.1e-10 38.5 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO02332.1 - 3.3e-08 33.1 4.5 5.3e-08 32.4 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDO02332.1 - 4.9e-07 29.5 7.8 8.3e-07 28.7 5.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EDO02332.1 - 3.5e-06 26.6 3.6 6.8e-06 25.7 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EDO02332.1 - 4.1e-05 23.5 6.1 0.00011 22.2 4.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDO02332.1 - 7.8e-05 22.3 4.8 0.00019 21.0 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO02332.1 - 0.0036 17.0 2.4 0.0065 16.2 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO02332.1 - 0.027 14.0 4.9 0.054 13.0 3.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EDO02332.1 - 0.039 13.4 0.4 0.07 12.6 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 EDO02332.1 - 1.8 8.4 6.5 5.1 7.0 4.5 1.7 1 1 0 1 1 1 0 IBR domain Prok-RING_4 PF14447.1 EDO02332.1 - 2.2 7.8 5.8 7.6 6.1 4.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 EXS PF03124.9 EDO02333.1 - 2.4e-101 339.2 10.8 2.7e-101 339.0 7.5 1.0 1 0 0 1 1 1 1 EXS family Velvet PF11754.3 EDO02334.1 - 6.9e-74 247.8 0.0 1.1e-73 247.1 0.0 1.3 1 1 0 1 1 1 1 Velvet factor PHY PF00360.15 EDO02337.1 - 0.072 12.2 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Phytochrome region DUF3602 PF12223.3 EDO02338.1 - 5.8e-15 55.4 6.6 4e-11 43.1 0.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF3445 PF11927.3 EDO02341.1 - 4e-75 252.4 0.0 4.9e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Peptidase_S28 PF05577.7 EDO02343.1 - 1.6e-36 125.8 0.0 2.1e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 eIF2A PF08662.6 EDO02344.1 - 2.4e-37 128.5 6.2 4.5e-36 124.3 0.4 3.7 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EDO02344.1 - 4.9e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO02344.1 - 3.6e-05 23.6 0.0 8.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO02344.1 - 8.3e-05 22.1 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDO02344.1 - 0.0008 19.1 0.3 0.22 11.4 0.0 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EDO02345.1 - 5e-131 437.6 9.7 5.9e-131 437.4 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribonuc_2-5A PF06479.7 EDO02347.1 - 1.1e-44 151.3 0.0 2.9e-44 150.0 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EDO02347.1 - 5.1e-41 140.5 0.0 7.9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02347.1 - 6.7e-21 74.5 0.0 9.7e-20 70.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EDO02347.1 - 5.9e-07 28.7 0.2 9.5e-05 21.7 0.0 3.8 4 0 0 4 4 4 1 PQQ enzyme repeat Kdo PF06293.9 EDO02347.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.1 EDO02347.1 - 0.0084 15.5 2.3 0.17 11.3 0.4 2.8 1 1 0 2 2 2 1 PQQ-like domain YrbL-PhoP_reg PF10707.4 EDO02347.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EDO02347.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family SWIB PF02201.13 EDO02348.1 - 7.3e-27 92.8 1.1 2e-26 91.4 0.1 2.2 3 0 0 3 3 3 1 SWIB/MDM2 domain DEK_C PF08766.6 EDO02348.1 - 5e-15 55.0 1.3 1.7e-14 53.2 0.5 2.0 2 0 0 2 2 2 1 DEK C terminal domain FliT PF05400.8 EDO02348.1 - 0.061 13.7 2.1 0.48 10.8 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliT NST1 PF13945.1 EDO02348.1 - 0.22 11.5 5.4 0.38 10.8 3.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Ldr_toxin PF13940.1 EDO02355.1 - 0.094 12.5 0.4 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system ANT PF03374.9 EDO02356.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain DUF1365 PF07103.6 EDO02357.1 - 4e-26 91.5 0.0 7.3e-26 90.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.5 EDO02358.1 - 3.1e-23 81.5 1.1 3.1e-23 81.5 0.8 2.1 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EDO02358.1 - 6e-08 32.4 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EDO02358.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EDO02358.1 - 0.0045 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 EDO02358.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CDV3 PF15359.1 EDO02358.1 - 0.25 11.4 3.4 0.48 10.5 2.4 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 ArsA_ATPase PF02374.10 EDO02362.1 - 1.4e-114 382.2 0.0 1.6e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EDO02362.1 - 2e-16 60.0 0.1 1.1e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO02362.1 - 3.5e-08 33.5 0.0 2.7e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EDO02362.1 - 1.8e-06 27.3 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EDO02362.1 - 3.5e-05 23.3 0.3 0.0012 18.3 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EDO02362.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO02362.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EDO02362.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 EDO02362.1 - 0.025 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ YhjQ PF06564.7 EDO02362.1 - 0.026 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 EDO02362.1 - 0.042 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FYVE_2 PF02318.11 EDO02362.1 - 0.063 13.1 0.7 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_18 PF13238.1 EDO02362.1 - 0.078 13.2 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AIP3 PF03915.8 EDO02362.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PhoH PF02562.11 EDO02362.1 - 0.12 11.5 0.0 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Transthyretin PF00576.16 EDO02363.1 - 9.3e-24 83.4 1.2 3.8e-21 75.0 0.9 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 EDO02363.1 - 0.0017 18.3 0.2 0.014 15.4 0.1 2.0 1 1 1 2 2 2 1 Carboxypeptidase regulatory-like domain FeoB_N PF02421.13 EDO02363.1 - 0.033 13.4 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Sugar_tr PF00083.19 EDO02365.1 - 1.2e-121 406.4 37.5 1.4e-121 406.2 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO02365.1 - 2e-20 72.8 35.3 2e-20 72.8 24.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DHquinase_I PF01487.10 EDO02367.1 - 7.6e-61 205.6 0.0 1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF3970 PF13113.1 EDO02367.1 - 0.017 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Fungal_trans PF04082.13 EDO02370.1 - 7.3e-22 77.4 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EDO02373.1 - 5.9e-14 51.5 30.4 5.9e-14 51.5 21.1 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 EDO02374.1 - 4.5e-153 510.0 20.6 5.6e-153 509.7 14.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EDO02374.1 - 0.16 10.9 11.5 0.44 9.5 0.7 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Glyco_hydro_17 PF00332.13 EDO02376.1 - 3.8e-06 26.1 0.3 3.8e-06 26.1 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EDO02376.1 - 0.0014 17.4 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 SPT16 PF08644.6 EDO02377.1 - 3.6e-58 195.7 1.8 8.2e-58 194.5 0.1 2.4 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EDO02377.1 - 1.1e-53 181.1 0.1 2.9e-53 179.7 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EDO02377.1 - 2.3e-23 82.8 0.0 4e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EDO02377.1 - 8.7e-22 76.9 0.1 2.4e-21 75.5 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ERG4_ERG24 PF01222.12 EDO02378.1 - 8.7e-141 469.3 21.2 1e-140 469.1 14.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UCH PF00443.24 EDO02379.1 - 4.2e-48 163.7 0.0 6e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO02379.1 - 3.2e-17 62.9 0.0 9.9e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 EDO02380.1 - 6.5e-07 29.2 9.3 1.1e-06 28.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO02380.1 - 1e-06 28.2 7.3 2e-06 27.3 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO02380.1 - 2.2e-06 27.2 5.1 3.7e-06 26.5 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO02380.1 - 4.2e-06 26.5 7.2 7.7e-06 25.6 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDO02380.1 - 4.2e-06 26.5 6.2 3.1e-05 23.7 4.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDO02380.1 - 3.4e-05 23.4 5.6 6.2e-05 22.6 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDO02380.1 - 0.089 12.5 6.6 0.16 11.6 2.9 2.4 2 0 0 2 2 2 0 RING-type zinc-finger DUF3694 PF12473.3 EDO02383.1 - 2e-45 153.9 0.0 3.4e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EDO02383.1 - 0.084 12.9 0.4 0.2 11.7 0.3 1.7 1 0 0 1 1 1 0 Kinesin protein 1B Kinesin PF00225.18 EDO02384.1 - 2.7e-112 374.8 0.0 3.9e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain FHA PF00498.21 EDO02384.1 - 3.3e-05 23.9 0.0 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 1 FHA domain zf-CCHC PF00098.18 EDO02385.1 - 2.1e-46 153.6 55.3 4.2e-08 32.7 1.0 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EDO02385.1 - 1.5e-10 40.5 47.0 0.12 12.0 0.8 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EDO02385.1 - 3.4e-05 23.4 44.9 0.37 10.5 1.0 7.0 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EDO02385.1 - 0.00088 18.7 43.4 0.56 9.7 1.3 7.2 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EDO02385.1 - 0.23 11.1 44.8 0.24 11.0 0.3 7.2 6 1 1 7 7 7 0 Zinc knuckle MFS_1 PF07690.11 EDO02386.1 - 4e-35 121.1 54.7 7.9e-35 120.1 36.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO02386.1 - 0.00073 18.2 38.2 0.043 12.3 3.4 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter SAE2 PF08573.5 EDO02392.1 - 1.4e-28 99.4 0.4 1.4e-28 99.4 0.3 4.1 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus LMBR1 PF04791.11 EDO02392.1 - 7.5 5.0 6.1 13 4.1 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC50 PF03381.10 EDO02393.1 - 1e-95 320.1 0.1 1.2e-95 319.8 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CTP_transf_2 PF01467.21 EDO02400.1 - 0.0011 19.0 1.2 0.0075 16.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase AA_permease_2 PF13520.1 EDO02401.1 - 4.9e-40 137.3 53.3 6.5e-40 136.9 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO02401.1 - 1.6e-12 46.5 47.4 2.1e-12 46.1 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_11 PF14833.1 EDO02403.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PTH2 PF01981.11 EDO02404.1 - 0.068 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 SBP_bac_6 PF13343.1 EDO02405.1 - 1.8e-14 53.6 1.2 1e-13 51.2 0.8 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.1 EDO02405.1 - 1.7e-10 41.1 5.3 4.6e-10 39.6 3.7 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EDO02405.1 - 8.3e-05 22.4 3.1 0.00012 21.8 1.9 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EDO02405.1 - 9.3e-05 22.1 0.2 0.00015 21.4 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Lactamase_B PF00753.22 EDO02407.1 - 0.00034 20.3 0.0 0.00034 20.3 0.0 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ammonium_transp PF00909.16 EDO02408.1 - 3.6e-110 368.1 28.3 4.2e-110 367.9 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family NAD_binding_8 PF13450.1 EDO02409.1 - 6.4e-12 45.3 0.3 1.1e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO02409.1 - 1.8e-07 30.3 0.7 3.1e-07 29.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDO02409.1 - 2.1e-07 30.3 0.2 3e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO02409.1 - 6.8e-07 28.1 0.4 1.1e-06 27.4 0.2 1.4 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EDO02409.1 - 1.1e-06 27.9 0.0 1.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EDO02409.1 - 8.3e-06 26.0 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO02409.1 - 1.4e-05 24.2 0.3 1.8e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO02409.1 - 4.1e-05 23.5 0.1 5.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO02409.1 - 0.00014 22.2 0.1 0.00022 21.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO02409.1 - 0.00026 20.1 0.3 0.00045 19.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EDO02409.1 - 0.00067 18.6 0.1 0.00095 18.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EDO02409.1 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EDO02409.1 - 0.0023 17.0 0.1 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EDO02409.1 - 0.037 13.4 0.1 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EDO02409.1 - 0.068 12.9 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDO02409.1 - 0.069 12.0 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EDO02409.1 - 0.79 9.3 2.8 0.41 10.2 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Senescence PF06911.7 EDO02410.1 - 0.028 14.1 3.9 0.041 13.5 2.7 1.2 1 0 0 1 1 1 0 Senescence-associated protein TFIIIC_sub6 PF10419.4 EDO02411.1 - 5.7e-15 54.4 0.1 9.7e-15 53.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit CBM_5_12 PF02839.9 EDO02411.1 - 0.029 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Methyltransf_23 PF13489.1 EDO02412.1 - 4.5e-12 45.9 0.0 6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO02412.1 - 1.6e-09 38.1 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO02412.1 - 3.3e-06 26.7 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02412.1 - 3.7e-05 24.2 0.0 5.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02412.1 - 5.8e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO02412.1 - 0.00039 19.5 0.0 0.00055 19.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EDO02412.1 - 0.0023 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EDO02412.1 - 0.0056 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EDO02412.1 - 0.0076 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EDO02412.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_9 PF08003.6 EDO02412.1 - 0.013 14.1 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UPF0020 PF01170.13 EDO02412.1 - 0.042 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EDO02412.1 - 0.08 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Prenylcys_lyase PF07156.9 EDO02412.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase 2Fe-2S_thioredx PF01257.14 EDO02413.1 - 4.3e-60 201.5 0.1 5.4e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin MIP PF00230.15 EDO02414.1 - 6.4e-07 29.0 0.0 8.1e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Augurin PF15187.1 EDO02414.1 - 0.084 12.7 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 MARVEL PF01284.18 EDO02415.1 - 1.2e-18 67.2 13.8 1.6e-18 66.8 9.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3278 PF11683.3 EDO02415.1 - 0.03 14.2 0.2 0.3 11.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) DUF3328 PF11807.3 EDO02415.1 - 0.045 13.4 0.0 0.045 13.4 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) TraL PF07178.6 EDO02415.1 - 0.91 9.5 6.5 25 4.9 5.3 2.5 1 1 1 2 2 2 0 TraL protein DnaJ PF00226.26 EDO02416.1 - 2.3e-25 88.0 1.3 3.6e-25 87.4 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDO02416.1 - 4e-16 58.8 17.2 7.1e-16 58.0 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EDO02416.1 - 1e-11 44.5 0.0 5.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EDO02416.1 - 0.012 15.2 10.1 0.31 10.7 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C3HC4_3 PF13920.1 EDO02416.1 - 4.3 7.0 7.8 3.2 7.4 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.22 EDO02417.1 - 6.6e-23 81.1 0.0 1.6e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO02417.1 - 9.1e-11 41.9 0.0 6.3e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EDO02417.1 - 4.2e-07 29.2 0.1 7.8e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EDO02417.1 - 6.3e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 EDO02417.1 - 3.6e-05 23.3 0.1 0.00014 21.5 0.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 EDO02417.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease ApbA PF02558.11 EDO02418.1 - 4.8e-31 107.2 0.0 6.6e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDO02418.1 - 5.4e-29 100.7 0.1 9.1e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Gln-synt_C PF00120.19 EDO02419.1 - 3.4e-64 216.4 0.0 4.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EDO02420.1 - 7.5e-18 64.9 0.4 1.1e-17 64.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO02420.1 - 7e-15 55.4 0.0 9.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO02420.1 - 0.0011 18.6 0.7 0.002 17.8 0.5 1.4 1 1 0 1 1 1 1 KR domain DDE_1 PF03184.14 EDO02421.1 - 2.6e-11 43.0 0.1 5.7e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Polysacc_deac_1 PF01522.16 EDO02422.1 - 4.3e-11 42.5 0.0 7.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Citrate_synt PF00285.16 EDO02423.1 - 1.6e-103 346.1 0.0 1.9e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 EDO02423.1 - 0.0031 16.2 0.0 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 ICL PF00463.16 EDO02424.1 - 4.6e-184 612.4 2.0 6.5e-122 407.4 0.1 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.1 EDO02424.1 - 2.1e-11 43.4 0.1 5.7e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fungal_trans_2 PF11951.3 EDO02426.1 - 0.00081 18.0 0.4 0.00096 17.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGL PF08450.7 EDO02427.1 - 8.9e-27 94.0 0.3 1.3e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EDO02427.1 - 2.3e-05 24.3 0.0 6.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EDO02427.1 - 0.00084 19.3 0.0 0.0066 16.4 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 EDO02427.1 - 0.073 13.0 1.0 22 5.2 0.1 3.6 3 0 0 3 3 3 0 NHL repeat PQQ_3 PF13570.1 EDO02427.1 - 0.5 10.7 4.4 36 4.7 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain zf-H2C2_2 PF13465.1 EDO02428.1 - 5.7e-07 29.5 15.1 1e-05 25.5 3.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO02428.1 - 2.9e-06 27.1 12.4 0.008 16.4 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO02428.1 - 0.0011 19.2 18.0 0.017 15.4 0.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EDO02428.1 - 0.0075 16.4 11.0 0.022 14.9 2.8 2.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EDO02428.1 - 0.053 13.1 11.5 0.066 12.8 0.4 2.7 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EDO02428.1 - 0.064 13.1 7.0 0.17 11.8 1.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-RING_2 PF13639.1 EDO02429.1 - 9.2e-13 47.8 3.6 1.4e-12 47.2 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO02429.1 - 9.2e-09 35.2 1.1 1.9e-08 34.2 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO02429.1 - 9.5e-07 28.7 3.1 1.5e-06 28.1 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO02429.1 - 2e-06 27.3 2.6 3.6e-06 26.5 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO02429.1 - 6.5e-06 25.7 1.8 1.1e-05 25.0 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO02429.1 - 2.1e-05 24.1 3.5 3.3e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EDO02429.1 - 6.2e-05 22.4 1.7 0.00014 21.2 1.2 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDO02429.1 - 7.4e-05 22.3 0.4 0.00029 20.4 0.2 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO02429.1 - 8.4e-05 22.3 0.7 0.00017 21.3 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.1 EDO02429.1 - 0.001 18.7 2.2 0.0023 17.6 1.5 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger RINGv PF12906.2 EDO02429.1 - 0.0076 16.2 1.5 0.016 15.2 1.1 1.6 1 1 0 1 1 1 1 RING-variant domain zf-C3HC4_4 PF15227.1 EDO02429.1 - 0.01 15.6 3.3 0.021 14.7 2.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF694 PF05107.7 EDO02429.1 - 0.026 13.7 0.2 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF694) Methyltransf_11 PF08241.7 EDO02429.1 - 0.031 14.7 0.1 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Baculo_p74_N PF08404.5 EDO02429.1 - 0.047 12.4 0.2 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal zf-RING_4 PF14570.1 EDO02429.1 - 0.089 12.3 4.0 0.15 11.6 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CHDCT2 PF08074.6 EDO02429.1 - 0.16 11.6 2.3 0.33 10.6 1.3 1.6 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain UPF0547 PF10571.4 EDO02429.1 - 0.91 9.2 6.6 1.8 8.3 0.2 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 ABC_tran PF00005.22 EDO02431.1 - 1.1e-47 161.8 0.4 1e-24 87.3 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EDO02431.1 - 9e-16 58.6 4.3 0.0029 17.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EDO02431.1 - 6e-12 45.2 0.4 0.0051 16.0 0.0 4.3 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO02431.1 - 1.5e-08 34.0 0.4 0.0069 15.9 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO02431.1 - 2e-07 31.5 2.4 0.0076 16.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EDO02431.1 - 3.7e-07 29.5 0.0 0.36 9.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EDO02431.1 - 2.5e-06 26.7 0.0 0.0097 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDO02431.1 - 3.1e-06 27.1 0.0 0.11 12.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EDO02431.1 - 1.4e-05 25.9 0.0 0.092 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDO02431.1 - 2e-05 24.3 0.1 0.38 10.6 0.0 3.6 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EDO02431.1 - 2.1e-05 25.0 0.0 0.045 14.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Chromo PF00385.19 EDO02431.1 - 6.3e-05 22.5 0.5 0.00016 21.2 0.1 2.0 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.1 EDO02431.1 - 0.00015 21.9 0.0 0.16 12.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EDO02431.1 - 0.00025 21.0 0.0 0.045 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDO02431.1 - 0.0007 19.1 2.5 1.6 8.1 0.1 3.6 4 0 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 EDO02431.1 - 0.0016 18.2 1.0 0.37 10.5 0.2 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 HEAT_2 PF13646.1 EDO02431.1 - 0.0027 17.9 1.6 1.4 9.2 0.2 3.0 1 1 1 2 2 2 1 HEAT repeats AAA_13 PF13166.1 EDO02431.1 - 0.0031 16.0 0.1 1.2 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO02431.1 - 0.0037 17.1 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDO02431.1 - 0.0037 17.0 0.0 0.37 10.6 0.0 3.1 3 0 0 3 3 3 1 Dynamin family CLASP_N PF12348.3 EDO02431.1 - 0.0046 16.3 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal AAA_18 PF13238.1 EDO02431.1 - 0.0085 16.3 0.1 2.7 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO02431.1 - 0.014 15.0 0.8 0.94 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EDO02431.1 - 0.02 14.2 0.0 8.4 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDO02431.1 - 0.02 15.0 0.1 2 8.6 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDO02431.1 - 0.021 14.9 0.1 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 EDO02431.1 - 0.025 14.0 0.1 4.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EDO02431.1 - 0.028 14.1 0.4 6.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3584 PF12128.3 EDO02431.1 - 0.05 10.9 3.4 1.5 6.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF815 PF05673.8 EDO02431.1 - 0.065 12.1 0.1 12 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 EDO02431.1 - 0.071 11.6 3.0 18 3.7 0.0 3.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EDO02431.1 - 0.082 11.9 0.3 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EDO02431.1 - 0.28 10.6 3.2 9 5.7 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF1275 PF06912.6 EDO02432.1 - 6.3e-34 117.0 10.1 7.4e-34 116.7 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.17 EDO02432.1 - 0.3 9.8 8.8 0.03 13.1 1.7 1.9 2 0 0 2 2 2 0 Acyltransferase family DUF2142 PF09913.4 EDO02432.1 - 0.61 8.6 7.0 0.058 12.0 1.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) Ion_trans PF00520.26 EDO02433.1 - 0.025 13.8 0.7 0.025 13.8 0.5 1.1 1 0 0 1 1 1 0 Ion transport protein TraL PF07178.6 EDO02433.1 - 0.89 9.6 3.2 0.94 9.5 2.2 1.0 1 0 0 1 1 1 0 TraL protein DUF3040 PF11239.3 EDO02433.1 - 3.9 7.6 8.7 3.8 7.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Glyco_transf_28 PF03033.15 EDO02434.1 - 3.5e-17 62.4 0.0 6.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EDO02434.1 - 0.00027 19.6 0.0 0.0018 16.9 0.1 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase M11L PF11099.3 EDO02435.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Apoptosis regulator M11L like Aft1_HRR PF11787.3 EDO02437.1 - 1.8e-19 70.5 3.8 1.8e-19 70.5 2.6 4.4 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 EDO02437.1 - 3.2e-12 46.2 5.0 8.4e-12 44.8 3.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO02437.1 - 5.8e-09 35.6 6.2 5.8e-09 35.6 4.3 2.7 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_HRA PF11786.3 EDO02437.1 - 1e-06 28.8 2.9 5e-06 26.6 2.0 2.3 1 1 0 1 1 1 1 Aft1 HRA domain Aft1_OSA PF11785.3 EDO02437.1 - 0.0013 19.2 1.2 0.0013 19.2 0.8 3.8 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 EDO02437.1 - 0.0015 18.8 3.6 0.0015 18.8 2.5 2.9 4 0 0 4 4 4 1 bZIP Maf transcription factor Macoilin PF09726.4 EDO02437.1 - 0.012 13.9 24.2 0.016 13.4 16.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Pox_Ag35 PF03286.9 EDO02437.1 - 1.2 8.6 15.3 3.5 7.1 10.6 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GST_N_3 PF13417.1 EDO02438.1 - 9.7e-12 44.9 0.1 2.7e-11 43.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO02438.1 - 0.0059 16.5 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO02438.1 - 0.021 14.6 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EDO02441.1 - 1.1e-59 196.3 15.4 1.4e-14 53.3 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat RVT_1 PF00078.22 EDO02441.1 - 1.3e-26 93.2 0.5 3.3e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NACHT PF05729.7 EDO02441.1 - 3.9e-24 85.1 0.2 8.3e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain RNase_H PF00075.19 EDO02441.1 - 7.9e-14 52.1 0.0 2e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 RNase H AAA_16 PF13191.1 EDO02441.1 - 0.0028 17.6 0.1 0.0089 16.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO02441.1 - 0.0031 17.6 0.6 0.028 14.5 0.0 2.9 2 1 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EDO02441.1 - 0.0036 16.9 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 EDO02441.1 - 0.0057 16.2 2.5 67 3.3 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat AAA PF00004.24 EDO02441.1 - 0.032 14.4 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO02441.1 - 0.05 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DDE_1 PF03184.14 EDO02442.1 - 2.7e-38 131.2 0.0 4.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO02442.1 - 3.1e-16 58.9 0.0 2.1e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO02442.1 - 3e-06 27.0 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO02442.1 - 0.00041 19.8 0.7 0.00099 18.6 0.1 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDO02442.1 - 0.0036 17.2 0.1 0.04 13.9 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3400 PF11880.3 EDO02442.1 - 0.0079 15.3 0.2 0.79 8.9 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3400) UPF0180 PF03698.8 EDO02442.1 - 0.056 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) HTH_AsnC-type PF13404.1 EDO02442.1 - 0.082 12.4 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.1 EDO02442.1 - 0.16 12.1 2.8 0.39 10.8 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn helix MCM2_N PF12619.3 EDO02445.1 - 1.8 8.5 7.5 2.1 8.2 5.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Iso_dh PF00180.15 EDO02448.1 - 6.7e-71 239.0 0.0 7.9e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.1 EDO02449.1 - 4e-67 226.6 0.2 4e-67 226.6 0.1 1.5 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.17 EDO02450.1 - 2.2e-26 91.2 0.2 5.7e-13 48.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO02450.1 - 9.1e-23 80.0 0.0 2.3e-10 40.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO02450.1 - 2.9e-12 46.2 2.2 0.00012 21.7 0.1 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO02450.1 - 0.0016 18.1 0.1 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Peroxin-13_N PF04088.8 EDO02451.1 - 0.0061 16.5 1.8 0.0067 16.3 0.3 1.7 2 0 0 2 2 2 1 Peroxin 13, N-terminal region AIG2_2 PF13772.1 EDO02451.1 - 0.097 12.7 0.1 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 AIG2-like family DUF3632 PF12311.3 EDO02453.1 - 1.4e-36 126.0 1.1 2.2e-36 125.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Asparaginase PF00710.15 EDO02455.1 - 6.2e-67 225.6 1.4 7e-67 225.5 1.0 1.0 1 0 0 1 1 1 1 Asparaginase RHIM PF12721.2 EDO02455.1 - 3.4 8.1 6.2 3.2 8.2 0.3 3.0 3 0 0 3 3 3 0 RIP homotypic interaction motif DUF3129 PF11327.3 EDO02458.1 - 1.1e-57 194.8 10.4 1.4e-57 194.4 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) MatE PF01554.13 EDO02459.1 - 3.7e-39 133.9 22.0 2.1e-24 85.9 4.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EDO02459.1 - 9.9e-07 28.6 5.0 9.9e-07 28.6 3.4 3.2 2 2 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 EDO02459.1 - 0.0034 16.8 1.4 0.0094 15.4 1.0 1.7 1 0 0 1 1 1 1 Interferon-induced transmembrane protein RVT_1 PF00078.22 EDO02460.1 - 6.6e-19 68.1 0.1 1.9e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 EDO02460.1 - 1.3e-17 63.4 0.0 2.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO02460.1 - 7.9e-10 39.1 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDO02460.1 - 5.9e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.5 EDO02460.1 - 7.8e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EDO02460.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.21 EDO02461.1 - 2.3e-07 30.9 0.0 3.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain MTHFR_C PF12225.3 EDO02462.1 - 0.018 14.4 0.4 0.032 13.7 0.3 1.5 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal Zn_clus PF00172.13 EDO02462.1 - 0.058 13.3 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APG6 PF04111.7 EDO02462.1 - 0.088 11.8 0.7 0.11 11.5 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RVT_1 PF00078.22 EDO02463.1 - 4e-21 75.3 0.0 4.5e-15 55.5 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDO02463.1 - 3.1e-12 46.1 0.0 9.2e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDO02463.1 - 0.013 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 RNase H Exo_endo_phos PF03372.18 EDO02463.1 - 0.016 15.1 1.1 0.031 14.2 0.8 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EDO02464.1 - 6.9e-38 130.1 0.0 1.3e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDO02464.1 - 4.5e-15 55.2 0.3 1.8e-14 53.4 0.2 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDO02464.1 - 6.3e-15 55.6 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDO02464.1 - 0.00016 21.7 0.1 0.00032 20.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF993 PF06187.6 EDO02464.1 - 0.13 10.7 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Btz PF09405.5 EDO02465.1 - 1e-27 96.7 3.7 1.9e-27 95.8 1.7 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Glyco_hydro_7 PF00840.15 EDO02469.1 - 8.8e-200 663.5 24.0 8.8e-200 663.5 16.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 7 SpoIIIAH PF12685.2 EDO02475.1 - 1.4 8.3 12.6 1.7 8.1 8.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1510 PF07423.6 EDO02475.1 - 2 7.7 32.6 2.6 7.3 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 EDO02475.1 - 2.5 6.5 6.4 2.6 6.4 4.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-CCCH PF00642.19 EDO02476.1 - 0.023 14.3 2.2 0.038 13.6 1.6 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec1 PF00995.18 EDO02477.1 - 1.1e-153 512.9 0.0 1.3e-153 512.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.27 EDO02480.1 - 1.7e-33 113.2 4.9 1.4e-05 24.7 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.7 EDO02480.1 - 0.019 14.6 0.2 19 5.0 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF218 PF02698.12 EDO02481.1 - 0.00046 19.7 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Pro-kuma_activ PF09286.6 EDO02482.1 - 1.5e-41 141.7 0.4 3.1e-41 140.7 0.3 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDO02482.1 - 9.8e-08 31.4 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family LMWPc PF01451.16 EDO02483.1 - 2e-26 92.9 0.0 2.3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EDO02485.1 - 5.9e-83 276.5 0.3 8.9e-83 275.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDO02485.1 - 4.3e-31 106.4 0.0 8.3e-31 105.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDO02485.1 - 1.6e-21 76.3 4.4 2.8e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EDO02485.1 - 1.1e-08 35.1 0.0 9.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDO02485.1 - 2.3e-08 33.9 11.4 2.3e-08 33.9 7.9 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Abhydrolase_6 PF12697.2 EDO02487.1 - 2.3e-06 27.6 0.0 2.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO02487.1 - 0.00011 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PLDc PF00614.17 EDO02488.1 - 9.4e-16 57.0 1.3 1e-06 28.3 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EDO02488.1 - 8e-12 45.0 0.0 2.1e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EDO02488.1 - 0.0043 16.8 0.1 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 PX domain COQ7 PF03232.8 EDO02489.1 - 7.8e-54 181.7 1.3 8.7e-54 181.5 0.9 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PLC-beta_C PF08703.5 EDO02489.1 - 0.001 18.8 1.8 0.0012 18.5 1.2 1.1 1 0 0 1 1 1 1 PLC-beta C terminal UPF0184 PF03670.8 EDO02489.1 - 0.064 13.4 0.4 0.091 12.9 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) EcsC PF12787.2 EDO02489.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family DUF342 PF03961.8 EDO02489.1 - 0.094 11.1 0.1 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1635 PF07795.6 EDO02489.1 - 0.25 10.6 2.0 0.31 10.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Plus-3 PF03126.13 EDO02490.1 - 3.2e-37 126.8 0.1 2.9e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain GCP5-Mod21 PF14609.1 EDO02492.1 - 0.089 10.8 0.0 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Glyco_trans_2_3 PF13632.1 EDO02493.1 - 1.3e-48 165.3 3.9 3.1e-48 164.0 2.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO02493.1 - 4.8e-07 29.8 0.1 1.5e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDO02493.1 - 4.2e-05 23.2 0.4 0.00021 21.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDO02493.1 - 0.00041 19.6 0.0 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Trehalase PF01204.13 EDO02498.1 - 2.4e-191 636.8 0.0 2.9e-191 636.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EDO02498.1 - 3e-15 55.1 1.4 5.1e-15 54.4 1.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 EDO02499.1 - 5.4e-274 909.2 0.6 6.2e-274 909.0 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDO02499.1 - 4.2e-11 42.5 0.1 8.2e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MRF_C1 PF13887.1 EDO02499.1 - 0.15 11.0 0.1 0.33 10.0 0.1 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 RRM_1 PF00076.17 EDO02500.1 - 3.8e-49 164.1 0.8 1.4e-16 59.8 0.1 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO02500.1 - 2.2e-38 130.0 0.1 1.5e-11 44.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO02500.1 - 8.7e-25 86.3 0.2 1.7e-07 30.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO02500.1 - 4.8e-07 29.4 0.0 0.046 13.5 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EDO02500.1 - 5.5e-05 22.3 3.4 5.5e-05 22.3 2.3 2.1 2 0 0 2 2 2 1 Lsm interaction motif RRM_3 PF08777.6 EDO02500.1 - 0.00082 19.1 0.1 0.11 12.3 0.0 3.6 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM PF05172.8 EDO02500.1 - 0.0077 15.9 0.0 0.32 10.7 0.0 3.2 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Ribosomal_L22 PF00237.14 EDO02501.1 - 1.3e-18 66.9 0.3 6.9e-09 35.5 0.7 2.4 1 1 1 2 2 2 2 Ribosomal protein L22p/L17e DUF4283 PF14111.1 EDO02501.1 - 0.06 12.4 0.7 3.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Fibritin_C PF07921.7 EDO02501.1 - 0.21 11.4 2.0 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Fibritin C-terminal region Sulfate_transp PF00916.15 EDO02502.1 - 6.3e-07 28.6 5.5 2.6e-06 26.6 0.4 2.6 2 0 0 2 2 2 2 Sulfate transporter family SPC12 PF06645.8 EDO02502.1 - 0.43 10.4 4.2 0.4 10.5 0.2 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MRC1 PF09444.5 EDO02503.1 - 3.8e-36 124.5 20.8 3.8e-36 124.5 14.4 7.2 7 1 1 8 8 8 3 MRC1-like domain DDE_1 PF03184.14 EDO02505.1 - 0.00031 19.9 0.0 0.00035 19.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CBM_5_12_2 PF14600.1 EDO02505.1 - 0.0031 17.1 0.1 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 Cellulose-binding domain Jiraiya PF15038.1 EDO02506.1 - 0.0088 15.4 0.1 0.0088 15.4 0.1 1.0 1 0 0 1 1 1 1 Jiraiya DUF2970 PF11174.3 EDO02506.1 - 1.5 8.4 4.5 2.1 7.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) UTP15_C PF09384.5 EDO02507.1 - 1.5e-49 167.4 0.0 2.7e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EDO02507.1 - 1e-28 98.1 1.4 1.4e-08 34.2 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Utp12 PF04003.7 EDO02507.1 - 0.0045 16.8 0.1 0.083 12.8 0.1 2.3 1 1 0 1 1 1 1 Dip2/Utp12 Family TH1 PF04858.8 EDO02507.1 - 0.065 11.3 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 TH1 protein L31 PF09784.4 EDO02507.1 - 0.19 11.8 4.4 0.36 10.9 1.5 2.5 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 zf-C2H2 PF00096.21 EDO02508.1 - 0.018 15.3 0.6 0.018 15.3 0.4 4.4 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO02508.1 - 0.019 15.2 1.0 0.019 15.2 0.7 4.7 5 1 0 5 5 5 0 C2H2-type zinc finger DnaJ_CXXCXGXG PF00684.14 EDO02508.1 - 0.07 13.1 0.1 0.07 13.1 0.0 2.7 1 1 0 2 2 2 0 DnaJ central domain HypA PF01155.14 EDO02508.1 - 0.15 11.7 5.1 0.24 11.1 1.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Not3 PF04065.10 EDO02510.1 - 7.2e-101 336.3 27.8 1.3e-100 335.4 19.3 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EDO02510.1 - 4.7e-43 146.2 10.2 1.4e-42 144.7 7.1 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EDO02510.1 - 0.014 14.9 3.7 0.036 13.6 2.6 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EDO02510.1 - 0.014 15.3 6.8 0.073 13.0 0.4 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sec5 PF15469.1 EDO02510.1 - 0.8 9.4 12.9 0.55 9.9 1.4 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Poty_PP PF08440.5 EDO02510.1 - 1.1 8.3 7.5 0.045 12.8 0.9 1.7 2 0 0 2 2 2 0 Potyviridae polyprotein Snapin_Pallidin PF14712.1 EDO02510.1 - 3 8.2 11.5 8.1 6.8 0.9 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.1 EDO02510.1 - 6.2 6.9 15.2 0.43 10.6 2.7 3.6 4 0 0 4 4 4 0 Syntaxin-like protein Tyr_Deacylase PF02580.11 EDO02511.1 - 6.5e-47 159.1 0.4 7.7e-47 158.9 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Lge1 PF11488.3 EDO02511.1 - 0.27 11.4 1.1 0.55 10.4 0.3 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Pro_isomerase PF00160.16 EDO02512.1 - 3e-46 157.4 0.7 6.5e-46 156.3 0.3 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EDO02512.1 - 1.3e-12 47.1 17.6 1e-06 28.2 0.3 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EDO02512.1 - 4e-08 32.5 5.9 1.8e-05 24.2 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02512.1 - 2.3e-07 30.1 3.8 0.00017 21.0 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO02512.1 - 1.5e-05 24.8 4.7 0.00014 21.6 1.8 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO02512.1 - 0.00019 20.9 0.2 0.00019 20.9 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02512.1 - 0.00021 21.6 2.8 0.041 14.5 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02512.1 - 0.00032 21.2 3.9 0.0031 18.1 1.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO02512.1 - 0.061 13.8 1.2 0.22 12.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO02512.1 - 1.1 9.6 5.2 0.25 11.7 1.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 EDO02513.1 - 1.5e-45 155.2 0.1 5e-45 153.6 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase MRP-L20 PF12824.2 EDO02516.1 - 3.2e-58 196.3 7.6 3.7e-58 196.1 5.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EDO02516.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Neugrin zf-H2C2_5 PF13909.1 EDO02518.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Pkinase PF00069.20 EDO02520.1 - 1.1e-34 119.7 0.0 1.2e-32 113.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02520.1 - 2.5e-18 66.0 0.0 5.8e-15 55.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO02520.1 - 0.0028 16.6 0.0 0.0084 15.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Dynamin_N PF00350.18 EDO02523.1 - 1e-20 74.2 0.0 2.3e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDO02523.1 - 4.9e-12 45.2 0.0 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EDO02523.1 - 2.9e-05 23.9 0.3 0.00083 19.3 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EDO02523.1 - 0.0022 17.4 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EDO02523.1 - 0.0055 17.1 0.0 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EDO02523.1 - 0.0077 15.3 0.8 0.075 12.1 0.0 2.8 3 0 0 3 3 3 1 AIG1 family AAA_21 PF13304.1 EDO02523.1 - 0.0081 16.1 0.1 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDO02523.1 - 0.025 14.5 1.3 0.41 10.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EDO02523.1 - 0.04 14.2 0.2 0.04 14.2 0.1 3.4 2 2 0 2 2 2 0 AAA domain Vac7 PF12751.2 EDO02525.1 - 4.6e-170 565.6 9.3 4.6e-170 565.6 6.5 2.1 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 UPF0121 PF03661.8 EDO02526.1 - 0.082 12.0 0.0 0.091 11.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) CECR6_TMEM121 PF14997.1 EDO02529.1 - 0.32 10.5 3.1 1.1 8.8 0.2 2.3 3 0 0 3 3 3 0 CECR6/TMEM121 family DUF4233 PF14017.1 EDO02529.1 - 1 9.2 5.4 0.26 11.2 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Sugar_tr PF00083.19 EDO02530.1 - 1.2e-102 343.8 30.7 1.4e-102 343.6 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO02530.1 - 1.2e-22 80.1 32.4 1.2e-22 80.1 22.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDO02530.1 - 0.00014 20.4 1.7 0.00014 20.4 1.2 3.9 1 1 1 4 4 4 2 MFS/sugar transport protein HSP9_HSP12 PF04119.7 EDO02531.1 - 9.5e-25 86.4 7.3 9.5e-25 86.4 5.1 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 EDO02531.1 - 4.3 7.5 6.7 12 6.1 0.5 2.8 1 1 1 2 2 2 0 MT0933-like antitoxin protein Epiglycanin_TR PF05647.6 EDO02531.1 - 5.1 6.9 8.7 11 5.8 5.9 1.8 1 1 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like PRP1_N PF06424.7 EDO02532.1 - 1.6e-53 180.5 6.8 4.4e-53 179.1 4.7 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EDO02532.1 - 2.4e-28 96.0 30.9 0.014 16.0 0.1 13.6 5 3 9 14 14 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02532.1 - 1.5e-22 79.6 15.2 4.8e-05 23.9 0.4 8.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO02532.1 - 1.7e-22 79.5 10.7 4.6e-08 33.2 0.2 9.2 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02532.1 - 5.6e-14 51.5 15.7 8.5e-05 22.1 0.0 8.2 5 3 3 9 9 9 4 TPR repeat TPR_2 PF07719.12 EDO02532.1 - 2.3e-12 45.8 10.5 0.25 11.3 0.0 9.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO02532.1 - 1.4e-07 30.8 1.0 0.079 12.7 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO02532.1 - 6.5e-07 29.0 7.3 32 5.0 0.0 9.4 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.1 EDO02532.1 - 2.4e-06 26.8 19.0 0.12 11.4 5.1 5.7 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02532.1 - 2.5e-06 26.8 2.3 0.042 13.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO02532.1 - 3.1e-06 27.0 5.8 0.11 12.4 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO02532.1 - 1.2e-05 25.3 11.6 26 5.5 0.0 9.6 12 0 0 12 12 10 0 Tetratricopeptide repeat Suf PF05843.9 EDO02532.1 - 0.00012 21.9 2.0 1.1 8.9 0.0 4.4 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_21 PF09976.4 EDO02532.1 - 0.00039 20.3 12.8 0.024 14.5 1.3 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO02532.1 - 0.00075 19.3 2.0 1.2 9.0 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO02532.1 - 0.01 15.5 2.5 56 3.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3808 PF10300.4 EDO02532.1 - 0.075 11.5 0.9 4.8 5.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) Ribosomal_S18 PF01084.15 EDO02534.1 - 8.8e-13 47.9 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_S4 PF00163.14 EDO02535.1 - 1.5e-11 44.5 0.1 1.6e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO02536.1 - 1.5e-07 30.7 0.0 3.5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 S4 domain META PF03724.11 EDO02537.1 - 0.0018 18.0 0.7 0.69 9.7 0.1 2.3 1 1 1 2 2 2 2 META domain SNAP-25 PF00835.14 EDO02538.1 - 0.0056 17.4 0.6 0.0056 17.4 0.4 2.8 3 0 0 3 3 3 1 SNAP-25 family PPR_2 PF13041.1 EDO02540.1 - 0.018 15.0 2.0 33 4.5 0.0 5.6 5 1 1 6 6 6 0 PPR repeat family OpuAC PF04069.7 EDO02540.1 - 0.11 11.8 0.2 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system ThiF PF00899.16 EDO02541.1 - 1.6e-27 95.9 0.0 2.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EDO02541.1 - 0.042 13.9 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 EDO02542.1 - 3e-26 91.0 1.5 4.6e-26 90.4 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EDO02542.1 - 2.1e-05 25.3 0.1 6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO02542.1 - 5.9e-05 23.3 0.0 0.00031 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EDO02542.1 - 0.0012 18.2 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EDO02542.1 - 0.083 12.7 0.2 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cys_rich_CWC PF14375.1 EDO02542.1 - 0.43 10.5 10.4 0.86 9.5 7.2 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC DUF2910 PF11139.3 EDO02543.1 - 0.26 10.3 2.6 1.2 8.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF202 PF02656.10 EDO02543.1 - 0.64 10.2 3.2 27 5.0 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF202) DUF3827 PF12877.2 EDO02545.1 - 0.0096 14.0 2.3 0.011 13.9 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) NinF PF05810.7 EDO02545.1 - 0.013 15.2 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 NinF protein CMV_1a PF12467.3 EDO02545.1 - 0.73 10.1 5.5 0.98 9.7 3.8 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family UPF0561 PF10573.4 EDO02545.1 - 1.2 8.9 5.8 1.1 9.1 3.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 SUR7 PF06687.7 EDO02547.1 - 1 8.8 5.2 3.3 7.2 3.7 1.7 1 1 0 1 1 1 0 SUR7/PalI family S1-like PF14444.1 EDO02548.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 S1-like DUF4407 PF14362.1 EDO02551.1 - 0.2 10.5 1.5 0.21 10.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_12 PF13424.1 EDO02553.1 - 2e-09 37.2 1.2 1.2e-07 31.5 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02553.1 - 9.7e-06 25.1 2.0 2e-05 24.1 0.3 2.3 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.1 EDO02553.1 - 2.4e-05 23.7 0.3 1.5 8.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO02553.1 - 0.002 17.9 3.1 0.02 14.7 0.1 3.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO02553.1 - 0.0021 17.8 0.1 0.78 9.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02553.1 - 0.0085 16.7 0.3 0.021 15.4 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02553.1 - 0.021 15.4 2.2 0.61 10.8 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02553.1 - 0.022 14.3 5.4 0.4 10.3 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO02553.1 - 0.059 13.7 1.4 0.24 11.7 0.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DDE_Tnp_IS66 PF03050.9 EDO02553.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family Glyco_hydro_3 PF00933.16 EDO02554.1 - 1e-89 300.5 0.0 1.4e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDO02554.1 - 2.1e-59 200.8 0.1 2.3e-58 197.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDO02554.1 - 1.5e-22 79.2 0.1 3.1e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Apq12 PF12716.2 EDO02554.1 - 0.52 10.0 2.3 0.96 9.1 1.6 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF1353 PF07087.6 EDO02557.1 - 0.037 13.5 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Ipi1_N PF12333.3 EDO02559.1 - 7.8e-28 96.4 0.1 1.1e-26 92.7 0.0 2.4 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF262 PF03235.9 EDO02560.1 - 0.0013 18.7 0.0 0.004 17.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 Pyrid_oxidase_2 PF13883.1 EDO02561.1 - 1.4e-45 155.1 0.0 1.8e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.9 EDO02562.1 - 5.5e-28 96.5 8.6 6.3e-28 96.3 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DDE_1 PF03184.14 EDO02563.1 - 1e-19 70.5 0.0 1.8e-14 53.4 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO02563.1 - 6.7e-08 32.2 0.1 2.5e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain GATA PF00320.22 EDO02564.1 - 7.6e-17 60.3 2.1 1.9e-16 59.1 1.5 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EDO02564.1 - 1.1e-14 53.6 4.7 2.1e-14 52.7 3.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 EDO02564.1 - 0.0085 16.6 2.5 0.0085 16.6 1.7 3.7 3 0 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus DUF3809 PF12723.2 EDO02566.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) DASH_Hsk3 PF08227.6 EDO02569.1 - 3.9e-20 71.7 1.6 5.6e-20 71.2 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Acetyltransf_3 PF13302.1 EDO02571.1 - 8.1e-22 77.9 0.1 9.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO02571.1 - 0.027 14.4 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_gyraseB PF00204.20 EDO02571.1 - 0.067 12.4 1.3 0.098 11.8 0.9 1.3 1 0 0 1 1 1 0 DNA gyrase B Fasciclin PF02469.17 EDO02572.1 - 5.4e-48 162.2 0.0 3.3e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain XFP PF03894.10 EDO02572.1 - 0.099 12.2 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Pyridoxal_deC PF00282.14 EDO02573.1 - 3.3e-61 206.8 0.0 4.7e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDO02573.1 - 3.2e-05 22.8 0.0 7.2e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V SRP-alpha_N PF04086.8 EDO02574.1 - 2.9e-86 289.3 0.0 3.9e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EDO02574.1 - 7e-52 175.7 0.2 1.3e-51 174.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EDO02574.1 - 5.2e-07 29.6 0.1 2e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EDO02574.1 - 9.6e-07 27.8 0.0 1.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EDO02574.1 - 1.8e-05 24.2 0.1 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EDO02574.1 - 0.0022 17.7 0.5 0.0053 16.4 0.1 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EDO02574.1 - 0.0024 17.9 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EDO02574.1 - 0.0044 16.6 0.1 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO02574.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EDO02574.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.13 EDO02574.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.22 EDO02574.1 - 0.019 15.2 0.6 0.17 12.2 0.1 2.7 3 1 0 3 3 3 0 ABC transporter MMR_HSR1 PF01926.18 EDO02574.1 - 0.023 14.6 0.0 0.079 12.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EDO02574.1 - 0.041 13.3 0.2 0.089 12.2 0.1 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EDO02574.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EDO02574.1 - 0.057 13.5 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO02574.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDO02574.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EDO02574.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FAM60A PF15396.1 EDO02574.1 - 0.17 11.6 0.2 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A YIF1 PF03878.10 EDO02575.1 - 1.6e-65 220.6 0.4 1.9e-65 220.3 0.3 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EDO02575.1 - 0.00019 20.9 7.5 0.0003 20.3 5.2 1.3 1 0 0 1 1 1 1 Yip1 domain DUF3632 PF12311.3 EDO02577.1 - 1.3e-14 54.4 0.1 9.5e-13 48.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) DNA_methylase PF00145.12 EDO02578.1 - 2e-31 109.3 0.0 1.8e-22 79.9 0.0 2.7 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase PTH2 PF01981.11 EDO02581.1 - 9e-48 160.7 0.4 1.3e-47 160.2 0.3 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4011 PF13195.1 EDO02582.1 - 0.014 15.3 0.4 0.022 14.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) DUF1451 PF07295.6 EDO02582.1 - 0.04 13.6 0.0 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) MFS_1 PF07690.11 EDO02583.1 - 8.5e-32 110.2 45.1 1.1e-29 103.2 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDO02583.1 - 2.5e-10 39.3 3.7 1.2e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EDO02583.1 - 1.7e-06 26.9 7.4 1.8e-06 26.8 3.8 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EDO02583.1 - 0.0039 15.3 10.4 0.067 11.3 1.8 3.1 2 1 1 3 3 3 3 Transmembrane secretion effector DUF2427 PF10348.4 EDO02584.1 - 2.5e-08 33.4 1.0 9.5e-08 31.5 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 EDO02584.1 - 1.3e-07 31.5 9.6 3.2e-07 30.2 6.7 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4401 PF14351.1 EDO02584.1 - 0.025 13.6 9.6 0.4 9.6 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) PhoQ_Sensor PF08918.5 EDO02584.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor DUF2852 PF11014.3 EDO02584.1 - 0.12 12.3 0.1 0.55 10.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF2306 PF10067.4 EDO02584.1 - 0.61 10.2 8.7 0.25 11.4 0.2 3.2 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) DUF4079 PF13301.1 EDO02584.1 - 1.8 8.5 9.4 0.18 11.7 2.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF998 PF06197.8 EDO02584.1 - 2.3 7.5 13.2 0.35 10.1 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Ceramidase PF05875.7 EDO02588.1 - 1.2e-33 116.4 7.5 1.9e-33 115.7 5.2 1.2 1 1 0 1 1 1 1 Ceramidase Cyt-b5 PF00173.23 EDO02589.1 - 4.6e-17 61.5 0.1 7.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C58 PF03543.9 EDO02589.1 - 0.26 10.7 2.4 0.14 11.5 0.4 1.5 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DOR PF14839.1 EDO02590.1 - 0.34 10.6 7.5 0.53 9.9 5.2 1.2 1 0 0 1 1 1 0 DOR family SIS PF01380.17 EDO02591.1 - 2.1e-08 33.8 0.2 6.8e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 EDO02591.1 - 8.5e-05 22.2 0.1 0.00023 20.8 0.1 1.7 1 1 1 2 2 2 1 SIS domain Transglut_core PF01841.14 EDO02591.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily Flavi_M PF01004.14 EDO02593.1 - 0.017 14.5 0.3 0.026 13.9 0.1 1.5 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M Tad PF13400.1 EDO02593.1 - 0.017 15.1 0.3 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like SP_C-Propep PF08999.5 EDO02593.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide CFEM PF05730.6 EDO02598.1 - 7.7e-14 51.2 13.8 1.7e-13 50.1 9.5 1.6 1 0 0 1 1 1 1 CFEM domain DUF883 PF05957.8 EDO02598.1 - 0.0092 16.3 3.1 0.019 15.3 2.1 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) AIP3 PF03915.8 EDO02598.1 - 3.5 6.4 5.5 4.4 6.1 3.8 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 HD PF01966.17 EDO02600.1 - 1e-06 28.7 0.8 4.4e-06 26.7 0.3 2.3 2 1 0 2 2 2 1 HD domain Clr5 PF14420.1 EDO02600.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain Peptidase_M19 PF01244.16 EDO02600.1 - 0.11 11.4 0.1 0.93 8.3 0.0 2.1 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Cyclase PF04199.8 EDO02601.1 - 2.6e-08 33.7 0.8 5.2e-08 32.7 0.5 1.5 1 1 0 1 1 1 1 Putative cyclase GYF PF02213.11 EDO02601.1 - 0.35 10.4 2.0 11 5.6 0.6 2.5 2 0 0 2 2 2 0 GYF domain PTS_2-RNA PF01885.11 EDO02602.1 - 2.1e-14 53.2 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family THOC7 PF05615.8 EDO02602.1 - 0.049 13.8 0.1 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1002 PF06207.6 EDO02602.1 - 0.051 12.8 0.0 0.15 11.3 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) Peptidase_M48 PF01435.13 EDO02604.1 - 8.3e-35 120.3 0.0 1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Kelch_3 PF13415.1 EDO02605.1 - 2.1e-21 75.5 11.9 6.3e-07 29.3 0.0 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO02605.1 - 1.3e-20 72.9 12.3 8.9e-07 28.5 0.0 7.0 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO02605.1 - 4.2e-20 70.9 2.8 6.2e-08 32.4 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EDO02605.1 - 7.8e-20 70.4 0.0 0.001 18.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EDO02605.1 - 1.9e-18 65.7 2.0 1.6e-07 30.7 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EDO02605.1 - 1.3e-12 46.9 9.9 6.2e-06 25.7 0.3 5.8 5 2 0 5 5 5 3 Kelch motif RAG2 PF03089.9 EDO02605.1 - 0.018 13.8 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 Recombination activating protein 2 dCMP_cyt_deam_1 PF00383.17 EDO02606.1 - 9.1e-12 44.5 0.1 1.2e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EDO02606.1 - 0.0034 17.0 0.2 0.0042 16.7 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DUF4363 PF14276.1 EDO02606.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Bd3614-deam PF14439.1 EDO02606.1 - 0.14 11.9 0.3 0.26 11.1 0.2 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase p450 PF00067.17 EDO02607.1 - 1.6e-31 109.4 0.0 1.8e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 EDO02609.1 - 3.3e-51 173.8 0.3 5.3e-51 173.2 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EDO02609.1 - 2.4e-27 94.6 0.3 8.5e-27 92.8 0.2 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EDO02609.1 - 1.8e-14 53.3 0.0 2.7e-13 49.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO02609.1 - 4.3e-07 29.9 2.7 1.2e-05 25.1 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO02609.1 - 5.5e-07 29.2 0.0 2.5e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EDO02609.1 - 0.025 13.3 5.7 0.034 12.9 0.0 2.5 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 MTBP_C PF14920.1 EDO02609.1 - 0.2 11.1 4.6 0.41 10.0 3.2 1.4 1 0 0 1 1 1 0 MDM2-binding AAA_11 PF13086.1 EDO02609.1 - 0.73 9.3 4.0 4.1 6.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF3425 PF11905.3 EDO02610.1 - 1.3e-31 109.2 0.9 2.1e-31 108.6 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDO02610.1 - 0.00072 19.4 18.2 0.0027 17.6 10.6 2.3 1 1 1 2 2 2 1 bZIP transcription factor Med4 PF10018.4 EDO02610.1 - 0.0019 17.6 0.1 0.004 16.5 0.1 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 EDO02610.1 - 0.0066 16.1 4.6 0.011 15.4 3.2 1.3 1 0 0 1 1 1 1 Mnd1 family BMFP PF04380.8 EDO02610.1 - 4.6 7.4 11.6 0.16 12.0 0.8 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity PseudoU_synth_2 PF00849.17 EDO02611.1 - 1.6e-28 99.6 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EDO02611.1 - 0.00042 19.6 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain 4HBT PF03061.17 EDO02612.1 - 0.00021 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.11 EDO02613.1 - 4.7e-33 114.3 28.8 4.7e-33 114.3 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.3 EDO02613.1 - 0.33 9.5 2.4 0.49 8.9 1.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter APH PF01636.18 EDO02615.1 - 1.4e-05 24.9 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDO02615.1 - 0.032 12.8 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Sigma70_r1_1 PF03979.9 EDO02616.1 - 0.0079 16.1 0.8 0.0098 15.8 0.6 1.2 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 DUF1840 PF08895.6 EDO02616.1 - 0.025 14.5 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) GFO_IDH_MocA PF01408.17 EDO02617.1 - 2.6e-19 69.9 0.0 4.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDO02617.1 - 0.0055 16.4 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EDO02617.1 - 0.051 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Foie-gras_1 PF11817.3 EDO02617.1 - 0.089 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 Sugar_tr PF00083.19 EDO02618.1 - 1.9e-15 56.4 20.7 5.3e-12 45.0 1.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EDO02618.1 - 3.4e-14 51.9 20.2 3.6e-09 35.3 5.7 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EDO02618.1 - 3.8e-13 48.8 39.1 5.9e-10 38.3 11.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2207 PF09972.4 EDO02618.1 - 0.15 10.6 1.0 7.4 5.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Adenylsucc_synt PF00709.16 EDO02620.1 - 1.5e-108 363.1 0.0 1.8e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase cobW PF02492.14 EDO02621.1 - 2.9e-36 124.5 0.0 3.6e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EDO02621.1 - 8.9e-06 24.6 0.8 7.5e-05 21.6 0.6 1.9 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EDO02621.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EDO02621.1 - 0.0085 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase CbiA PF01656.18 EDO02621.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EDO02621.1 - 0.028 15.2 0.2 0.049 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO02621.1 - 0.046 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.8 EDO02621.1 - 0.058 12.1 0.0 0.096 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus MobB PF03205.9 EDO02621.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EDO02621.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EDO02621.1 - 0.087 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EDO02621.1 - 0.087 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 EDO02621.1 - 0.088 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EDO02621.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO02621.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDO02621.1 - 0.11 12.6 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 EDO02621.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 EDO02621.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BING4CT PF08149.6 EDO02622.1 - 2.3e-38 129.5 0.0 1.8e-36 123.4 0.0 3.1 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EDO02622.1 - 9.2e-08 31.6 0.0 9.6e-05 22.1 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EDO02622.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region DUF663 PF04950.7 EDO02623.1 - 8.7e-106 353.2 0.0 1.6e-105 352.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDO02623.1 - 8.7e-24 82.8 0.1 3.3e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain RrnaAD PF00398.15 EDO02624.1 - 7.4e-61 205.4 0.0 9.8e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EDO02624.1 - 1.4e-10 41.2 0.0 2.1e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02624.1 - 3.2e-07 30.9 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO02624.1 - 2.5e-05 23.7 0.0 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EDO02624.1 - 0.0002 20.9 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO02624.1 - 0.00033 20.2 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EDO02624.1 - 0.0004 20.8 0.0 0.00084 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO02624.1 - 0.00044 19.4 0.0 0.00071 18.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDO02624.1 - 0.00044 20.0 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02624.1 - 0.00094 19.6 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EDO02624.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EDO02624.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EDO02624.1 - 0.021 15.1 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDO02624.1 - 0.051 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EDO02624.1 - 0.055 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EDO02624.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 QueT PF06177.6 EDO02625.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 QueT transporter phage_tail_N PF08400.5 EDO02625.1 - 0.079 12.6 0.7 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Sushi_2 PF09014.5 EDO02626.1 - 1.2 8.9 5.3 13 5.6 0.2 2.1 1 1 1 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Choline_kin_N PF04428.9 EDO02628.1 - 0.12 11.8 0.6 6 6.4 0.0 3.0 3 0 0 3 3 3 0 Choline kinase N terminus Excalibur PF05901.6 EDO02628.1 - 3.1 8.2 4.6 1.5e+02 2.8 0.0 3.6 4 0 0 4 4 4 0 Excalibur calcium-binding domain DUF619 PF04768.8 EDO02630.1 - 6.3e-53 178.6 0.1 1.2e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EDO02630.1 - 2.4e-29 102.0 0.0 6.9e-29 100.6 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EDO02630.1 - 7.6e-24 84.5 0.1 1.7e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family DapB_N PF01113.15 EDO02630.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EDO02631.1 - 4e-32 109.6 0.7 4.6e-32 109.4 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF515 PF04415.7 EDO02631.1 - 0.089 11.0 0.2 0.098 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Zn_clus PF00172.13 EDO02632.1 - 8e-07 28.8 11.0 1.4e-06 28.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDO02632.1 - 0.0015 17.1 0.9 0.0022 16.6 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_76 PF03663.9 EDO02633.1 - 5.9e-165 549.1 23.1 7.2e-165 548.8 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF588 PF04535.7 EDO02633.1 - 0.044 13.3 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Cu-oxidase_3 PF07732.10 EDO02635.1 - 5.7e-41 138.9 1.2 2.9e-39 133.4 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDO02635.1 - 6.9e-32 109.8 4.6 3.4e-28 97.8 0.9 4.0 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EDO02635.1 - 3.7e-25 88.6 0.2 2.3e-24 86.1 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase NAD_binding_4 PF07993.7 EDO02636.1 - 4.5e-34 117.4 0.0 6.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDO02636.1 - 1.2e-21 76.6 0.0 2.6e-21 75.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EDO02636.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EDO02636.1 - 1.6e-05 24.4 0.0 4.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDO02636.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.20 EDO02637.1 - 6e-57 192.7 0.0 3.1e-56 190.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02637.1 - 3.9e-27 94.9 0.6 1.3e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EDO02637.1 - 5e-07 30.1 0.5 1.5e-06 28.5 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO02637.1 - 0.00064 18.7 0.0 0.002 17.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO02637.1 - 0.0032 17.2 0.1 0.15 11.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family MOSC_N PF03476.11 EDO02638.1 - 4.8e-19 68.2 0.0 1.1e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EDO02638.1 - 1.8e-12 46.8 0.5 3.2e-11 42.8 0.4 2.1 1 1 0 1 1 1 1 MOSC domain His_biosynth PF00977.16 EDO02639.1 - 1.4e-47 161.9 1.4 6.6e-47 159.6 1.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EDO02639.1 - 5.9e-30 104.1 0.0 9.4e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EDO02639.1 - 5.4e-11 42.4 0.0 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDO02639.1 - 1.2e-07 31.4 0.0 2.8e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EDO02639.1 - 0.0011 18.4 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.12 EDO02639.1 - 0.026 13.3 0.0 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Glyco_hydro_16 PF00722.16 EDO02641.1 - 1.2e-21 76.8 1.3 2.4e-21 75.8 0.7 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF333 PF03891.10 EDO02643.1 - 0.13 12.0 0.5 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF333) Glyco_trans_2_3 PF13632.1 EDO02644.1 - 1.9e-48 164.7 2.5 4.4e-48 163.5 1.7 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO02644.1 - 2.1e-06 27.7 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDO02644.1 - 9e-05 22.2 0.0 0.00027 20.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDO02644.1 - 0.0034 16.6 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Amidase PF01425.16 EDO02645.1 - 7.9e-39 133.7 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_3 PF13302.1 EDO02646.1 - 3.2e-12 46.8 0.0 4.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_3 PF13738.1 EDO02647.1 - 1.6e-20 74.0 0.0 5e-20 72.4 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO02647.1 - 3.3e-15 55.2 2.1 8.4e-13 47.3 1.4 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDO02647.1 - 9.5e-12 44.7 0.0 3.5e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO02647.1 - 6.7e-08 31.8 0.0 2.6e-05 23.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDO02647.1 - 0.00039 20.2 0.0 0.056 13.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EDO02647.1 - 0.0026 16.8 0.0 0.0077 15.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EDO02647.1 - 0.0036 16.2 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO02647.1 - 0.052 13.9 0.0 0.42 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FB_lectin PF07367.6 EDO02647.1 - 0.075 12.6 0.5 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 Fungal fruit body lectin EAF PF09816.4 EDO02648.1 - 5e-21 74.7 1.4 1.4e-20 73.2 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase II transcription elongation factor Ribosomal_60s PF00428.14 EDO02648.1 - 0.012 15.9 6.5 0.012 15.9 4.5 3.0 4 0 0 4 4 4 0 60s Acidic ribosomal protein SET PF00856.23 EDO02649.1 - 0.25 11.6 1.9 1.6 9.0 0.0 2.8 3 1 0 3 3 3 0 SET domain MmgE_PrpD PF03972.9 EDO02650.1 - 2.6e-152 507.0 0.0 3e-152 506.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ASD2 PF08687.6 EDO02650.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF904 PF06005.7 EDO02653.1 - 0.13 12.5 0.1 0.14 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF904) EF-hand_7 PF13499.1 EDO02654.1 - 5.3e-11 42.4 0.4 0.00024 21.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO02654.1 - 2e-07 29.8 3.2 0.21 10.9 0.0 4.3 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDO02654.1 - 5.7e-07 28.8 1.4 0.0077 16.0 0.0 4.5 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 EDO02654.1 - 1.2e-06 27.9 4.9 0.00025 20.5 0.3 3.4 3 1 0 3 3 3 2 EF-hand domain pair LNS2 PF08235.8 EDO02654.1 - 0.0089 15.6 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Paf1 PF03985.8 EDO02654.1 - 0.028 13.1 0.7 0.038 12.7 0.5 1.2 1 0 0 1 1 1 0 Paf1 SPOUT_MTase PF02590.12 EDO02654.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase UPF0154 PF03672.8 EDO02654.1 - 0.064 12.8 0.0 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) eIF-5a PF01287.15 EDO02654.1 - 0.17 11.8 3.2 0.14 12.1 0.5 2.2 2 1 1 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold IBR PF01485.16 EDO02656.1 - 2e-12 46.7 6.9 5e-12 45.5 1.8 2.1 2 0 0 2 2 2 1 IBR domain FeS PF04060.8 EDO02656.1 - 0.029 13.9 1.5 0.029 13.9 1.1 2.7 4 0 0 4 4 4 0 Putative Fe-S cluster zf-RING_4 PF14570.1 EDO02656.1 - 0.083 12.4 7.0 3.3 7.3 1.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain OrfB_Zn_ribbon PF07282.6 EDO02656.1 - 1.1 8.9 7.4 0.7 9.6 0.3 2.7 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EDO02656.1 - 4.6 7.2 8.6 3.5 7.6 0.1 3.0 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.2 EDO02656.1 - 9.6 6.1 11.3 88 3.0 6.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF1687 PF07955.6 EDO02658.1 - 1.5e-16 60.5 0.1 7e-16 58.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) IMD PF08397.6 EDO02660.1 - 7e-05 22.2 2.6 0.00054 19.3 1.8 2.0 1 1 0 1 1 1 1 IRSp53/MIM homology domain Abhydrolase_2 PF02230.11 EDO02661.1 - 1.9e-53 181.1 0.0 2.2e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDO02661.1 - 1.4e-09 37.8 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO02661.1 - 5.6e-06 26.4 0.0 0.00046 20.1 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO02661.1 - 0.00015 21.0 0.0 0.0063 15.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EDO02661.1 - 0.0021 17.6 0.0 1.1 8.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EDO02661.1 - 0.0024 17.3 0.1 0.013 14.9 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EDO02661.1 - 0.0053 16.0 0.0 0.017 14.4 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 EDO02661.1 - 0.0057 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EDO02661.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EDO02661.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.15 EDO02661.1 - 0.053 12.9 0.1 0.4 10.0 0.1 2.2 1 1 1 2 2 2 0 Putative esterase DUF676 PF05057.9 EDO02661.1 - 0.14 11.4 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Pkinase PF00069.20 EDO02662.1 - 1.3e-17 63.8 0.0 2.7e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02662.1 - 0.00029 19.9 0.0 0.0043 16.1 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Lipase_GDSL PF00657.17 EDO02663.1 - 1e-14 54.9 0.4 1.7e-14 54.2 0.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDO02663.1 - 3.2e-13 50.2 0.3 5.3e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EDO02663.1 - 2.9e-06 27.1 0.1 4.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Herpes_capsid PF06112.6 EDO02663.1 - 0.71 9.8 5.2 1.3 9.0 3.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3510 PF12022.3 EDO02664.1 - 0.038 14.1 0.1 0.085 12.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Latrotoxin_C PF15658.1 EDO02664.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Latrotoxin C-terminal domain N-glycanase_C PF09113.5 EDO02665.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal RskA PF10099.4 EDO02666.1 - 0.04 13.6 0.2 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4064 PF13273.1 EDO02666.1 - 0.079 13.0 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) FeoB_N PF02421.13 EDO02667.1 - 0.17 11.1 0.1 6.7 5.9 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B TRI12 PF06609.8 EDO02668.1 - 2.4e-39 135.0 30.4 3e-39 134.7 21.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EDO02668.1 - 1.5e-20 73.2 52.4 1.5e-20 73.2 36.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO02668.1 - 3.1e-10 39.2 42.5 4.4e-10 38.7 9.0 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter UQ_con PF00179.21 EDO02670.1 - 2.9e-46 156.3 0.0 3.3e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO02670.1 - 0.00045 19.9 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDO02670.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EDO02670.1 - 0.072 12.9 0.1 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 EDO02671.1 - 1.8e-15 56.0 13.6 4.4e-06 26.3 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 EDO02671.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EDO02672.1 - 6.7e-18 64.3 22.4 6.2e-10 38.8 5.1 2.3 2 1 0 2 2 2 2 IBR domain GMC_oxred_N PF00732.14 EDO02674.1 - 1.6e-15 57.0 0.0 4.3e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO02674.1 - 1.8e-09 37.9 0.0 3.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDO02674.1 - 4.5e-09 35.6 1.6 6.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO02674.1 - 1e-07 31.1 2.1 1.2e-05 24.3 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EDO02674.1 - 1e-06 28.7 0.2 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO02674.1 - 2.3e-06 26.3 2.7 0.0008 17.9 1.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EDO02674.1 - 1.2e-05 25.5 0.2 0.044 13.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO02674.1 - 0.00026 19.9 3.1 0.00094 18.1 0.7 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EDO02674.1 - 0.0003 19.9 1.7 0.0012 17.9 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EDO02674.1 - 0.00052 19.1 0.3 0.002 17.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EDO02674.1 - 0.0067 16.4 0.7 0.019 14.9 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EDO02674.1 - 0.16 10.9 1.3 0.24 10.4 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDO02674.1 - 0.19 12.1 0.9 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.17 EDO02677.1 - 5.9e-06 26.3 0.1 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF3353 PF11833.3 EDO02677.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Acetyltransf_3 PF13302.1 EDO02679.1 - 3.8e-34 117.8 0.2 6e-34 117.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO02679.1 - 4.8e-07 29.7 0.1 7.7e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO02679.1 - 0.00025 20.9 0.6 0.00053 19.9 0.4 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family BTB PF00651.26 EDO02681.1 - 2.9e-23 81.9 0.6 3.1e-13 49.6 0.2 3.4 3 0 0 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EDO02681.1 - 1.7e-07 31.2 1.2 4.3e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EDO02681.1 - 2.6e-07 30.0 1.4 9.1e-07 28.3 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EDO02681.1 - 1.7e-06 28.2 0.0 6.5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO02681.1 - 3.3e-05 24.2 0.0 0.0001 22.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO02681.1 - 9.4e-05 22.3 0.2 0.002 18.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 EDO02682.1 - 1.1e-59 201.6 0.2 4.9e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02682.1 - 2.7e-36 124.9 0.0 2.3e-35 121.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO02682.1 - 0.00044 19.3 0.0 0.00099 18.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 EDO02682.1 - 0.0067 15.3 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF342 PF03961.8 EDO02682.1 - 0.089 11.1 1.3 0.17 10.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HasA PF06438.7 EDO02683.1 - 0.0062 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Heme-binding protein A (HasA) Baculo_PEP_C PF04513.7 EDO02685.1 - 1.4 8.7 8.9 1 9.1 1.4 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_7 PF03441.9 EDO02686.1 - 1.5e-55 188.3 0.0 2.1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EDO02686.1 - 1.9e-18 66.7 0.0 3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Sugar_tr PF00083.19 EDO02689.1 - 8.4e-97 324.5 18.6 9.7e-97 324.3 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO02689.1 - 3.1e-18 65.6 30.7 1.4e-15 56.9 5.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EDO02689.1 - 6.5e-06 26.0 8.0 0.0011 18.9 0.9 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) OATP PF03137.15 EDO02689.1 - 0.00063 17.9 0.2 0.00063 17.9 0.2 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ank_2 PF12796.2 EDO02691.1 - 2.1e-108 354.8 17.2 1.7e-17 63.4 0.0 16.8 7 3 9 17 17 17 16 Ankyrin repeats (3 copies) Ank PF00023.25 EDO02691.1 - 2.7e-86 279.3 39.0 9.1e-06 25.2 0.1 25.7 26 0 0 26 26 26 20 Ankyrin repeat Ank_4 PF13637.1 EDO02691.1 - 4.6e-73 240.4 30.3 6.8e-08 32.8 0.0 24.9 13 6 16 29 29 29 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO02691.1 - 4.1e-62 199.9 23.3 0.00041 20.3 0.0 25.5 27 0 0 27 27 27 14 Ankyrin repeat Ank_5 PF13857.1 EDO02691.1 - 1.1e-59 197.1 30.7 1.6e-05 24.9 0.0 22.1 19 4 7 26 26 26 16 Ankyrin repeats (many copies) NACHT PF05729.7 EDO02691.1 - 1e-06 28.4 0.1 3e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Zn_clus PF00172.13 EDO02698.1 - 1.3e-07 31.3 6.9 2.1e-07 30.7 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.1 EDO02699.1 - 2.8e-13 49.7 0.0 3.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO02699.1 - 1.2e-12 47.8 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO02699.1 - 1e-10 41.9 0.0 2.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02699.1 - 3e-10 40.4 0.0 5.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02699.1 - 5e-10 39.9 0.0 9.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO02699.1 - 1.8e-09 37.8 0.0 1.1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO02699.1 - 3e-08 33.0 0.0 6.8e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EDO02699.1 - 0.00036 20.5 0.0 0.00089 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO02699.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EDO02699.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase UCH PF00443.24 EDO02700.1 - 1.2e-54 185.2 0.0 1.5e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO02700.1 - 7.7e-15 55.1 0.0 3.2e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EDO02700.1 - 3.9e-11 42.1 0.1 1.1e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family ARPC4 PF05856.7 EDO02701.1 - 2.6e-77 258.0 4.0 2.9e-77 257.8 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) 4HBT_3 PF13622.1 EDO02704.1 - 6.8e-40 137.4 0.0 8.1e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EDO02704.1 - 4.9e-11 42.3 0.0 0.00028 20.5 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase AfsA PF03756.8 EDO02704.1 - 0.18 11.5 0.8 0.33 10.6 0.5 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain TFIIA PF03153.8 EDO02708.1 - 5.1 6.9 21.2 5.4 6.8 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.21 EDO02709.1 - 0.00037 20.6 3.5 0.0036 17.5 0.3 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO02709.1 - 0.019 15.2 1.1 0.019 15.2 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Pyridoxal_deC PF00282.14 EDO02713.1 - 4.2e-24 84.6 0.0 5.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EDO02713.1 - 0.00025 20.2 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EDO02713.1 - 0.00045 18.8 0.0 0.00069 18.2 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 EDO02713.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_52 PF07922.6 EDO02713.1 - 0.077 12.0 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 Methyltransf_23 PF13489.1 EDO02714.1 - 1.3e-14 54.2 0.0 2.4e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO02714.1 - 1.6e-07 31.0 0.0 1.1e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO02714.1 - 4.6e-07 30.2 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02714.1 - 2.9e-06 27.6 0.0 1.9e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO02714.1 - 2.8e-05 24.6 0.0 0.00042 20.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO02714.1 - 0.0068 16.7 0.0 0.033 14.5 0.0 2.2 3 1 0 3 3 2 1 Methyltransferase domain DUF938 PF06080.7 EDO02714.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) FtsJ PF01728.14 EDO02714.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CdhD PF03599.11 EDO02714.1 - 0.057 11.9 0.0 0.081 11.4 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit MTS PF05175.9 EDO02714.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EDO02714.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Rsm22 PF09243.5 EDO02714.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Ubie_methyltran PF01209.13 EDO02714.1 - 0.15 11.1 0.0 0.9 8.6 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_hydro_65m PF03632.10 EDO02715.1 - 8.9e-75 251.6 2.2 7.9e-74 248.5 1.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EDO02715.1 - 9.4e-08 31.6 0.2 0.0052 16.1 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 65, N-terminal domain ArfGap PF01412.13 EDO02716.1 - 1.4e-32 111.9 6.6 3.2e-28 97.8 0.0 3.2 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf DUF3140 PF11338.3 EDO02716.1 - 0.073 13.1 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Cupin_5 PF06172.6 EDO02717.1 - 8.4e-22 77.5 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Beta-lactamase PF00144.19 EDO02718.1 - 1e-35 123.3 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase WSC PF01822.14 EDO02721.1 - 6.1e-90 295.2 87.4 2.4e-19 69.0 9.0 5.3 5 0 0 5 5 5 5 WSC domain DUF1929 PF09118.6 EDO02721.1 - 4.1e-25 87.7 0.1 8.3e-25 86.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.6 EDO02721.1 - 4.3e-20 71.8 0.3 3.4e-15 55.7 0.1 4.4 3 2 1 4 4 4 2 Glyoxal oxidase N-terminus DNA_ligase_A_N PF04675.9 EDO02721.1 - 0.61 9.8 0.0 1.2 8.8 0.0 1.4 1 0 0 1 1 1 0 DNA ligase N terminus Catalase PF00199.14 EDO02723.1 - 5.2e-65 219.6 0.0 6.1e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Cupin_2 PF07883.6 EDO02724.1 - 2e-05 23.9 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain A_thal_3526 PF09713.5 EDO02724.1 - 0.0045 17.0 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) PhyH PF05721.8 EDO02725.1 - 8.2e-26 91.3 0.0 1.1e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EDO02725.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DIOX_N PF14226.1 EDO02726.1 - 0.0073 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDO02726.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Topoisom_I_N PF02919.10 EDO02726.1 - 0.12 11.6 0.5 0.18 11.1 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2462 PF09495.5 EDO02729.1 - 3.8e-20 72.4 7.9 3.8e-20 72.4 5.4 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Arginase PF00491.16 EDO02733.1 - 5.3e-89 298.2 0.0 6.7e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EDO02733.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 UPF0489 domain HET PF06985.6 EDO02734.1 - 2.8e-29 102.0 0.1 4.4e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FUSC_2 PF13515.1 EDO02737.1 - 2.1e-28 98.8 7.8 2.1e-28 98.8 5.4 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EDO02737.1 - 2.5e-12 46.0 0.7 9.5e-08 30.9 0.0 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 EDO02737.1 - 1.2e-08 34.1 23.6 0.00012 20.9 6.2 4.8 4 1 0 4 4 4 2 Aluminium activated malate transporter DUF2421 PF10334.4 EDO02737.1 - 5.5e-05 22.8 0.0 0.00043 19.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC-like PF12805.2 EDO02737.1 - 0.029 13.2 5.5 0.26 10.1 1.2 2.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF3035 PF11233.3 EDO02737.1 - 0.12 12.3 0.1 3.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) HTH_Tnp_Tc5 PF03221.11 EDO02738.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO02738.1 - 0.00044 19.4 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SHNi-TPR PF10516.4 EDO02739.1 - 4.8e-16 57.7 0.2 4.8e-16 57.7 0.1 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EDO02739.1 - 7e-08 32.2 7.2 0.00044 20.1 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02739.1 - 5.1e-07 29.2 6.0 0.00093 18.7 0.9 3.0 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO02739.1 - 0.00043 19.7 6.1 0.0096 15.4 1.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02739.1 - 0.0051 17.4 7.7 0.011 16.4 0.4 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO02739.1 - 0.16 11.9 5.1 0.82 9.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO02739.1 - 0.16 11.9 17.3 0.046 13.6 2.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO02739.1 - 0.18 11.6 1.7 12 5.9 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EDO02739.1 - 0.75 9.6 5.2 0.13 12.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.11 EDO02740.1 - 1.1e-54 184.8 0.1 1.9e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RabGAP-TBC PF00566.13 EDO02741.1 - 1.8e-50 171.4 0.0 2.5e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EDO02743.1 - 1e-36 124.3 0.1 2.9e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO02743.1 - 1e-27 95.8 0.0 9.2e-14 51.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO02743.1 - 2.9e-12 46.2 2.4 7.6e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO02743.1 - 0.0095 15.7 0.1 6.3 6.7 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Med15 PF09606.5 EDO02743.1 - 0.1 10.8 61.1 0.14 10.2 42.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HNH_2 PF13391.1 EDO02744.1 - 5.5e-07 29.2 0.1 1.3e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Nucleoplasmin PF03066.10 EDO02744.1 - 0.067 12.6 5.0 0.13 11.7 3.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Methyltransf_18 PF12847.2 EDO02746.1 - 5.3e-16 59.1 0.0 8.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO02746.1 - 3.6e-15 56.0 0.0 4.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO02746.1 - 8.1e-15 55.0 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO02746.1 - 1.2e-14 54.1 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO02746.1 - 3.2e-14 53.0 0.0 4.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO02746.1 - 4.3e-13 49.5 0.0 7.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO02746.1 - 1e-11 44.3 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EDO02746.1 - 3.7e-10 39.8 0.0 5.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EDO02746.1 - 2.3e-06 27.1 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EDO02746.1 - 5.2e-05 22.6 0.0 0.00021 20.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 EDO02746.1 - 5.4e-05 22.2 0.0 9.4e-05 21.4 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.8 EDO02746.1 - 0.00036 19.7 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EDO02746.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EDO02746.1 - 0.0063 15.5 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_20 PF12147.3 EDO02746.1 - 0.0064 15.3 0.0 0.0083 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 EDO02746.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NNMT_PNMT_TEMT PF01234.12 EDO02746.1 - 0.073 12.0 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family tRNA_U5-meth_tr PF05958.6 EDO02746.1 - 0.09 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Bin3 PF06859.7 EDO02746.1 - 0.095 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Spermine_synth PF01564.12 EDO02746.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase Gar1 PF04410.9 EDO02746.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region FmrO PF07091.6 EDO02746.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) HTH_Tnp_Tc5 PF03221.11 EDO02747.1 - 1.7e-11 43.7 0.0 2.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO02747.1 - 2.2e-05 23.6 0.1 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF3404 PF11884.3 EDO02747.1 - 0.048 12.5 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) C2 PF00168.25 EDO02748.1 - 3.5e-14 52.4 0.0 6.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain UPF0546 PF10639.4 EDO02749.1 - 8.7e-38 128.6 0.6 1.3e-37 128.1 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EDO02749.1 - 0.00033 20.6 4.1 0.00074 19.5 0.9 2.2 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EDO02749.1 - 0.0028 17.8 3.3 0.0028 17.8 2.3 1.8 1 1 1 2 2 2 1 Multidrug resistance efflux transporter DUF751 PF05421.6 EDO02749.1 - 0.59 10.4 4.9 5.3 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF751) DUF2011 PF09428.5 EDO02750.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Proteasome PF00227.21 EDO02751.1 - 7.7e-46 155.7 0.0 1.1e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO02751.1 - 5e-13 48.0 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EDO02751.1 - 0.08 12.4 0.7 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EDO02752.1 - 1.2e-25 88.8 0.2 2.8e-25 87.6 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) YwhD PF08741.5 EDO02752.1 - 0.028 13.8 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 YwhD family Claudin_2 PF13903.1 EDO02753.1 - 0.016 14.9 7.2 0.052 13.2 5.0 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.6 EDO02753.1 - 0.079 12.6 11.8 0.32 10.7 8.2 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Oxidored_q3 PF00499.15 EDO02753.1 - 0.59 9.8 4.7 0.23 11.2 1.2 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Fzo_mitofusin PF04799.8 EDO02753.1 - 0.68 9.3 3.4 1.2 8.5 2.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region Competence PF03772.11 EDO02753.1 - 0.86 8.6 8.0 0.11 11.4 2.3 2.0 2 1 0 2 2 2 0 Competence protein Wzy_C PF04932.10 EDO02753.1 - 2.5 7.8 5.1 2.5 7.8 2.2 1.8 2 0 0 2 2 2 0 O-Antigen ligase DUF4538 PF15061.1 EDO02753.1 - 5.8 6.3 7.4 14 5.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Amastin PF07344.6 EDO02753.1 - 8 6.0 9.9 22 4.6 6.9 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein PhyH PF05721.8 EDO02755.1 - 5.8e-56 189.8 0.0 7e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EDO02755.1 - 0.033 14.4 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DDE_1 PF03184.14 EDO02756.1 - 0.012 14.7 1.2 0.67 9.0 0.1 2.2 1 1 1 2 2 2 0 DDE superfamily endonuclease BTB PF00651.26 EDO02758.1 - 2.3e-05 24.3 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EDO02759.1 - 1.5e-52 173.6 27.0 1.6e-08 34.0 0.1 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDO02759.1 - 0.0039 16.6 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.16 EDO02759.1 - 0.14 12.1 3.9 4.9 7.3 0.0 4.0 3 1 1 4 4 4 0 NHL repeat IRF PF00605.12 EDO02759.1 - 0.21 11.3 1.5 17 5.2 0.1 2.7 2 1 0 2 2 2 0 Interferon regulatory factor transcription factor PQQ_3 PF13570.1 EDO02759.1 - 1.2 9.5 17.6 9.8 6.6 0.1 6.7 5 2 2 7 7 7 0 PQQ-like domain PAP2 PF01569.16 EDO02760.1 - 5e-24 84.4 2.6 9.1e-24 83.5 1.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily Spc97_Spc98 PF04130.8 EDO02761.1 - 8.3e-122 407.2 0.0 1.1e-121 406.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 EDO02761.1 - 0.0084 15.9 0.2 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3921) SAGA-Tad1 PF12767.2 EDO02762.1 - 9.8e-66 221.9 0.0 1.4e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Rad21_Rec8_N PF04825.8 EDO02763.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein FA_desaturase PF00487.19 EDO02765.1 - 1.8e-12 47.2 20.1 1.8e-12 47.2 13.9 1.7 1 1 1 2 2 2 2 Fatty acid desaturase Lyase_1 PF00206.15 EDO02766.1 - 9.2e-111 369.9 0.0 1.3e-110 369.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EDO02766.1 - 1.3e-22 79.6 0.0 3.1e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus O-FucT PF10250.4 EDO02767.1 - 6.4e-08 32.0 0.9 1.9e-05 23.9 0.0 3.3 2 1 0 2 2 1 1 GDP-fucose protein O-fucosyltransferase SAPS PF04499.10 EDO02767.1 - 0.0044 15.7 4.3 0.0055 15.4 3.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein NPR3 PF03666.8 EDO02767.1 - 0.056 11.9 12.2 0.077 11.5 8.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.7 EDO02767.1 - 0.21 9.4 24.1 0.26 9.1 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EDO02767.1 - 0.36 10.0 15.8 0.58 9.3 10.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EDO02767.1 - 0.42 10.0 22.3 0.64 9.4 15.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.3 EDO02767.1 - 0.43 9.1 10.5 0.74 8.3 7.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1510 PF07423.6 EDO02767.1 - 0.46 9.8 27.9 0.75 9.1 19.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EDO02767.1 - 0.66 7.9 17.7 0.9 7.4 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.4 EDO02767.1 - 0.7 9.9 30.9 1.4 8.9 21.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.1 EDO02767.1 - 0.93 9.2 6.4 1.5 8.5 4.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RRN3 PF05327.6 EDO02767.1 - 1 7.4 6.4 1.4 6.9 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.1 EDO02767.1 - 1.2 8.7 14.0 2.5 7.6 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.9 EDO02767.1 - 3.2 7.2 21.7 5.4 6.4 15.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EDO02767.1 - 3.6 5.1 20.4 5 4.7 14.2 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 EDO02767.1 - 4.7 4.7 10.9 6.5 4.3 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EDO02767.1 - 6.4 5.1 34.8 9.4 4.5 24.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 EDO02767.1 - 6.9 6.6 27.9 11 5.9 19.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 UPF0560 PF10577.4 EDO02767.1 - 7.7 4.6 8.7 10 4.2 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.7 EDO02767.1 - 8.8 6.1 23.0 14 5.4 16.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4428 PF14471.1 EDO02770.1 - 0.063 13.0 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.21 EDO02773.1 - 5.1e-10 39.0 12.1 2.7e-05 24.2 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO02773.1 - 9.8e-10 38.0 5.9 5.7e-05 23.1 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO02773.1 - 9.7e-08 31.9 9.6 8e-06 25.8 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 EDO02773.1 - 0.023 14.4 6.9 0.21 11.3 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EDO02773.1 - 0.04 13.8 5.6 1 9.3 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHY PF05495.7 EDO02773.1 - 0.12 12.5 4.0 0.26 11.4 2.8 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_jaz PF12171.3 EDO02773.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DDE_1 PF03184.14 EDO02774.1 - 7.5e-41 139.6 0.7 1.2e-40 138.9 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO02774.1 - 1.2e-14 53.8 0.0 5.9e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDO02775.1 - 1.5e-07 30.8 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Ribosomal_S13_N PF08069.7 EDO02775.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain HTH_29 PF13551.1 EDO02775.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn helix RIO1 PF01163.17 EDO02775.1 - 0.031 13.6 0.2 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family HTH_Tnp_Tc5 PF03221.11 EDO02775.1 - 0.086 12.6 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Pkinase PF00069.20 EDO02776.1 - 7.5e-73 244.8 0.0 1.3e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02776.1 - 2.8e-32 111.8 0.0 1.9e-29 102.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO02776.1 - 1.9e-05 23.7 0.0 4.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO02776.1 - 0.0019 17.9 0.0 0.0062 16.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO02776.1 - 0.0036 16.3 0.1 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDO02776.1 - 0.0055 16.3 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase SMC_N PF02463.14 EDO02777.1 - 1.9e-24 86.1 0.0 3.3e-24 85.3 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDO02777.1 - 4.3e-21 76.1 0.6 4.3e-21 76.1 0.4 5.0 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EDO02777.1 - 0.00012 22.1 8.0 0.0004 20.4 0.0 3.3 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EDO02777.1 - 0.0035 16.8 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EDO02777.1 - 0.036 14.2 1.0 0.29 11.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO02777.1 - 0.19 11.1 0.0 0.19 11.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain Spc42p PF11544.3 EDO02778.1 - 0.074 12.9 0.3 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Spindle pole body component Spc42p AP-5_subunit_s1 PF15001.1 EDO02780.1 - 0.018 14.9 0.4 0.018 14.9 0.3 1.7 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 CBM_19 PF03427.8 EDO02780.1 - 0.035 13.8 3.7 0.063 13.0 2.6 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Asp-B-Hydro_N PF05279.6 EDO02780.1 - 2.3 8.0 14.8 3.9 7.2 10.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cyclin PF08613.6 EDO02781.1 - 5.6e-13 49.5 0.8 1e-12 48.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin VP4_haemagglut PF00426.13 EDO02781.1 - 0.68 7.8 4.6 0.96 7.3 3.2 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Wbp11 PF09429.5 EDO02784.1 - 9.5e-22 76.7 11.9 9.5e-22 76.7 8.2 2.2 3 0 0 3 3 3 1 WW domain binding protein 11 Cluap1 PF10234.4 EDO02784.1 - 0.11 11.6 1.7 0.19 10.8 1.2 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Lipoprotein_7 PF01540.11 EDO02784.1 - 0.21 10.6 2.7 0.3 10.1 1.9 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 EDO02784.1 - 0.24 10.6 3.9 0.53 9.5 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Paramyxo_C PF01692.13 EDO02784.1 - 0.37 10.3 2.6 0.71 9.4 1.8 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c POP1 PF06978.6 EDO02788.1 - 3.8e-64 215.8 8.6 7.5e-64 214.8 6.0 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EDO02788.1 - 2.1e-31 107.5 0.4 2.1e-31 107.5 0.3 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain ApbA PF02558.11 EDO02790.1 - 1.3e-25 89.6 0.0 1.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDO02790.1 - 1.7e-21 76.5 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.24 EDO02793.1 - 1.9e-36 125.0 0.1 3.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO02793.1 - 2.4e-24 84.9 0.0 9.6e-24 83.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO02793.1 - 3.5e-06 26.9 0.0 8.5e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDO02793.1 - 0.015 14.3 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 EDO02794.1 - 2.5e-06 27.2 0.4 1.6e-05 24.6 0.3 1.9 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Amidase PF01425.16 EDO02796.1 - 3.8e-45 154.5 0.0 2.7e-26 92.4 0.0 2.9 1 1 1 2 2 2 2 Amidase DUF92 PF01940.11 EDO02797.1 - 5e-63 212.2 3.3 6.6e-63 211.8 2.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Arteri_GP4 PF02497.10 EDO02797.1 - 0.048 13.5 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Arterivirus glycoprotein Pox_P21 PF05313.7 EDO02797.1 - 0.24 10.6 3.0 9.5 5.4 0.0 3.2 3 1 0 3 3 3 0 Poxvirus P21 membrane protein Tmemb_14 PF03647.8 EDO02797.1 - 0.27 11.6 3.4 1.5 9.2 0.2 3.1 3 0 0 3 3 3 0 Transmembrane proteins 14C TPR_11 PF13414.1 EDO02799.1 - 0.00022 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 TPR repeat Apc3 PF12895.2 EDO02799.1 - 0.0071 16.4 0.9 0.029 14.4 0.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EDO02799.1 - 0.0099 15.7 0.1 0.86 9.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat RRM_5 PF13893.1 EDO02799.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.1 EDO02799.1 - 0.12 12.3 0.0 19 5.2 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02799.1 - 0.14 11.8 0.2 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.6 EDO02802.1 - 3e-25 89.0 0.5 6.2e-25 87.9 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oest_recep PF02159.10 EDO02803.1 - 0.082 13.0 1.3 0.11 12.5 0.9 1.3 1 0 0 1 1 1 0 Oestrogen receptor AMP-binding PF00501.23 EDO02804.1 - 1.3e-72 244.5 0.0 1.1e-71 241.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO02804.1 - 5.9e-10 39.9 0.1 2.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L14e PF01929.12 EDO02806.1 - 8e-28 96.6 0.8 8e-28 96.6 0.6 1.7 1 1 1 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 EDO02806.1 - 3.7e-08 32.7 0.6 9.8e-08 31.4 0.4 1.7 1 0 0 1 1 1 1 KOW motif AAA_19 PF13245.1 EDO02806.1 - 0.027 14.2 0.5 0.065 12.9 0.3 1.8 1 1 0 1 1 1 0 Part of AAA domain NAC PF01849.13 EDO02807.1 - 1.3e-25 88.6 0.1 1.5e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EDO02807.1 - 0.0012 18.6 0.2 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain SelP_N PF04592.9 EDO02807.1 - 0.75 9.1 6.1 1.2 8.4 4.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.9 EDO02807.1 - 3.3 5.6 12.3 0.039 12.0 3.1 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF2946 PF11162.3 EDO02807.1 - 9 6.5 7.2 17 5.5 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Myc_N PF01056.13 EDO02807.1 - 9 5.3 11.7 0.36 9.9 3.8 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.7 EDO02808.1 - 7.9e-19 67.8 0.9 9.5e-19 67.6 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EDO02808.1 - 0.015 14.9 0.3 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b E3_UbLigase_R4 PF13764.1 EDO02808.1 - 0.063 11.1 0.2 0.074 10.9 0.2 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 RasGAP_C PF03836.10 EDO02808.1 - 0.076 12.7 0.8 0.14 11.8 0.3 1.5 1 1 0 1 1 1 0 RasGAP C-terminus Blt1 PF12754.2 EDO02808.1 - 0.085 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component Dor1 PF04124.7 EDO02808.1 - 0.096 11.1 1.5 0.12 10.8 1.0 1.1 1 0 0 1 1 1 0 Dor1-like family Syntaxin PF00804.20 EDO02808.1 - 0.15 12.2 2.6 0.25 11.5 1.7 1.5 1 1 0 1 1 1 0 Syntaxin DUF4515 PF14988.1 EDO02808.1 - 0.28 10.8 3.5 2.1 7.9 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) OmpH PF03938.9 EDO02808.1 - 0.44 10.4 5.5 1.5 8.7 3.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.2 EDO02808.1 - 3.5 7.4 7.8 6.2 6.6 1.9 2.3 1 1 0 2 2 2 0 Tropomyosin like Abhydrolase_3 PF07859.8 EDO02809.1 - 2e-22 79.8 0.0 5.8e-22 78.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO02809.1 - 0.0034 17.2 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO02809.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_26 PF13500.1 EDO02809.1 - 0.049 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain COesterase PF00135.23 EDO02809.1 - 0.053 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Fer4_19 PF06902.6 EDO02810.1 - 0.016 14.9 0.7 0.016 14.9 0.5 1.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster CorA PF01544.13 EDO02811.1 - 4.7e-08 32.4 0.1 8.1e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PGBA_C PF15437.1 EDO02811.1 - 0.14 12.2 7.7 0.36 10.9 5.3 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Zn_clus PF00172.13 EDO02812.1 - 0.23 11.3 10.5 0.59 10.0 7.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EDO02814.1 - 5.5e-12 45.4 0.0 7.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDO02814.1 - 7.9e-11 42.2 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding HhH-GPD PF00730.20 EDO02815.1 - 7.9e-13 48.6 0.0 1.8e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDO02815.1 - 0.00045 19.7 0.0 0.0012 18.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif GSH_synth_ATP PF03917.12 EDO02815.1 - 0.0025 16.4 0.0 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain AA_permease_2 PF13520.1 EDO02816.1 - 6.4e-42 143.5 38.4 7.9e-42 143.2 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO02816.1 - 6.3e-27 94.0 33.3 8.5e-27 93.6 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EDO02819.1 - 6.8e-08 32.4 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO02819.1 - 7.3e-08 32.4 0.1 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO02819.1 - 1e-05 25.6 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO02819.1 - 0.0048 16.7 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldedh PF00171.17 EDO02820.1 - 4.3e-106 355.0 0.0 5.2e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATase_2 PF00310.16 EDO02823.1 - 5.7e-19 68.0 0.0 1e-13 50.7 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDO02823.1 - 1.1e-14 54.4 0.0 2.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDO02823.1 - 1.5e-11 44.1 0.0 3.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EDO02823.1 - 3.4e-11 42.9 0.1 6.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EDO02823.1 - 6e-05 21.8 0.0 0.0001 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EDO02823.1 - 0.031 13.8 0.1 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 EDO02824.1 - 5.6e-38 130.5 21.0 1.5e-33 115.9 7.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 EDO02826.1 - 1.7e-19 69.2 0.1 3.7e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family RDD PF06271.7 EDO02826.1 - 0.59 10.0 4.0 1.8 8.4 0.7 2.1 2 0 0 2 2 2 0 RDD family Peroxidase_2 PF01328.12 EDO02827.1 - 7.6e-15 54.3 0.0 1.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.6 EDO02828.1 - 8.8e-24 84.2 0.1 1.4e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.26 EDO02829.1 - 6.7e-12 45.3 0.1 5.6e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Trypan_PARP PF05887.6 EDO02829.1 - 0.072 12.9 5.6 0.12 12.2 3.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dabb PF07876.7 EDO02831.1 - 1.7e-10 41.1 0.0 1.9e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DLH PF01738.13 EDO02832.1 - 1.8e-12 47.0 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDO02832.1 - 0.0004 20.1 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family SH3_1 PF00018.23 EDO02833.1 - 4.7e-11 41.9 0.3 8.5e-11 41.0 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO02833.1 - 2.3e-10 39.8 0.2 5e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO02833.1 - 8.4e-08 31.5 0.0 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Transaldolase PF00923.14 EDO02834.1 - 9e-18 64.4 0.8 4e-11 42.5 0.1 2.1 1 1 1 2 2 2 2 Transaldolase Nuclease_act PF08133.6 EDO02834.1 - 0.1 12.1 1.0 0.21 11.0 0.7 1.5 1 0 0 1 1 1 0 Anticodon nuclease activator family Eco57I PF07669.6 EDO02835.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Eco57I restriction-modification methylase MFS_1 PF07690.11 EDO02836.1 - 9.5e-35 119.9 37.2 9.5e-35 119.9 25.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO02836.1 - 3.7e-11 42.2 22.5 6.4e-11 41.4 15.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Dynamin_N PF00350.18 EDO02837.1 - 2.5e-31 108.7 0.0 8e-31 107.1 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDO02837.1 - 1.3e-15 56.9 1.7 4.2e-15 55.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EDO02837.1 - 6.9e-05 22.7 0.0 0.0005 19.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO02837.1 - 0.0039 17.6 0.0 0.015 15.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EDO02837.1 - 0.0067 16.7 0.0 2.2 8.5 0.0 2.9 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 EDO02837.1 - 0.017 14.1 0.1 2.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin V-ATPase_H_C PF11698.3 EDO02837.1 - 0.06 13.2 0.2 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 V-ATPase subunit H DUF4410 PF14366.1 EDO02837.1 - 0.09 12.5 1.1 1.3 8.7 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4410) DUF946 PF06101.6 EDO02838.1 - 9e-09 33.8 1.9 1.4e-08 33.1 1.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) FGGY_C PF02782.11 EDO02841.1 - 2.5e-76 255.7 0.5 4.4e-76 254.9 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDO02841.1 - 5.4e-50 169.9 0.0 7.9e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EDO02842.1 - 2.2e-40 138.5 2.5 2.8e-40 138.1 1.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein SNAP PF14938.1 EDO02844.1 - 5.7e-118 393.1 15.9 6.4e-118 392.9 11.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EDO02844.1 - 2.1e-09 37.1 10.5 9.1e-05 22.3 1.9 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02844.1 - 3.8e-08 32.8 13.7 0.0023 17.5 2.2 3.9 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.1 EDO02844.1 - 1.4e-07 30.7 6.2 1 9.3 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02844.1 - 2.6e-07 31.1 5.5 0.48 11.1 2.9 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO02844.1 - 1.4e-06 27.7 12.6 0.16 11.9 1.3 6.2 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO02844.1 - 9.8e-05 21.8 10.4 0.19 11.5 0.2 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02844.1 - 0.0001 21.7 14.2 0.5 10.0 1.4 5.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO02844.1 - 0.00013 22.1 14.7 7.5 7.2 0.1 6.4 4 2 3 7 7 6 1 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 EDO02844.1 - 0.011 14.3 1.0 1.2 7.6 0.1 2.4 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Foie-gras_1 PF11817.3 EDO02844.1 - 0.013 15.0 4.1 0.053 12.9 2.5 2.3 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_14 PF13428.1 EDO02844.1 - 0.015 15.8 10.2 23 5.9 0.2 5.4 2 1 4 6 6 6 0 Tetratricopeptide repeat DUF2521 PF10730.4 EDO02844.1 - 0.048 13.4 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) RPN7 PF10602.4 EDO02844.1 - 0.1 11.9 3.8 1 8.7 0.2 2.8 2 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 EDO02844.1 - 0.2 11.6 1.9 1.1 9.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4375 PF14300.1 EDO02844.1 - 1.6 8.7 6.6 1.8 8.5 0.4 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4375) NSF PF02071.15 EDO02844.1 - 1.9 9.4 15.7 2.9 8.8 0.5 6.2 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat Glu-tRNAGln PF02686.10 EDO02845.1 - 0.062 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.7 EDO02846.1 - 6.5e-124 413.2 3.6 6.5e-124 413.2 2.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EDO02846.1 - 0.00013 21.8 0.1 0.00034 20.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EDO02846.1 - 0.00061 20.0 1.4 0.0011 19.1 0.0 2.1 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 EDO02846.1 - 0.0037 16.8 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO02846.1 - 0.028 14.1 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family TraH PF06122.6 EDO02846.1 - 0.039 12.7 0.9 0.062 12.1 0.6 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein TcdA_TcdB_pore PF12920.2 EDO02846.1 - 0.15 9.9 4.4 0.24 9.2 3.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PXA PF02194.10 EDO02846.1 - 0.71 9.4 3.7 0.24 10.9 0.2 1.9 2 0 0 2 2 2 0 PXA domain Mus7 PF09462.5 EDO02847.1 - 8.4e-66 223.0 9.2 1.2e-50 172.9 0.2 3.4 1 1 1 3 3 3 3 Mus7/MMS22 family AAA PF00004.24 EDO02847.1 - 2.2e-38 131.4 0.0 7.6e-38 129.7 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO02847.1 - 0.00014 21.8 0.9 0.018 15.0 0.0 3.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDO02847.1 - 0.00031 20.8 0.1 0.018 15.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO02847.1 - 0.00043 19.4 0.0 0.00087 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO02847.1 - 0.00076 20.3 0.0 0.0032 18.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO02847.1 - 0.0042 16.9 0.0 0.018 14.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO02847.1 - 0.0062 16.4 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EDO02847.1 - 0.0082 15.8 0.2 0.028 14.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EDO02847.1 - 0.011 15.4 0.1 0.038 13.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EDO02847.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EDO02847.1 - 0.029 13.0 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EDO02847.1 - 0.042 12.9 0.1 0.11 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDO02847.1 - 0.091 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Asp PF00026.18 EDO02852.1 - 3.8e-66 223.4 7.6 4.9e-66 223.1 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO02852.1 - 1.6e-08 34.6 0.3 1.3e-07 31.7 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO02852.1 - 6.3e-06 26.6 3.9 0.07 13.6 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease Fimbrial_PilY2 PF14481.1 EDO02852.1 - 0.057 12.8 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 G_glu_transpept PF01019.16 EDO02853.1 - 1e-102 344.2 0.0 1.3e-102 343.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RF-1 PF00472.15 EDO02854.1 - 1.4e-32 111.9 1.6 3.8e-32 110.4 1.1 1.7 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EDO02854.1 - 3.3e-29 100.9 0.0 8.7e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 PCRF domain MIR PF02815.14 EDO02854.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 MIR domain OmpH PF03938.9 EDO02854.1 - 0.024 14.5 0.0 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_32 PF13654.1 EDO02854.1 - 0.035 12.7 0.3 0.057 12.0 0.2 1.2 1 0 0 1 1 1 0 AAA domain IBN_N PF03810.14 EDO02854.1 - 0.14 12.1 0.8 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Importin-beta N-terminal domain BLOC1_2 PF10046.4 EDO02854.1 - 0.24 11.5 2.8 7.2 6.8 0.9 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3328 PF11807.3 EDO02856.1 - 9.7e-25 87.5 1.0 1.1e-24 87.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TAFH PF07531.9 EDO02857.1 - 0.002 17.7 0.0 9.6 5.9 0.0 4.2 1 1 5 6 6 6 2 NHR1 homology to TAF Mad3_BUB1_I PF08311.7 EDO02857.1 - 0.049 13.4 0.6 2.9 7.6 0.0 3.5 1 1 1 3 3 3 0 Mad3/BUB1 homology region 1 DUF2186 PF09952.4 EDO02857.1 - 0.069 13.4 2.1 36 4.5 0.0 5.0 1 1 5 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2186) MFS_1 PF07690.11 EDO02858.1 - 7.2e-20 70.9 30.0 7.2e-20 70.9 20.8 2.7 1 1 1 3 3 3 1 Major Facilitator Superfamily ABC_tran PF00005.22 EDO02859.1 - 2.2e-46 157.5 0.0 2.2e-27 96.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO02859.1 - 8e-12 45.1 10.1 8e-12 45.1 7.0 3.6 3 1 1 4 4 4 1 ABC transporter transmembrane region AAA_29 PF13555.1 EDO02859.1 - 5.7e-08 32.1 1.8 0.0012 18.3 0.0 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EDO02859.1 - 1.8e-07 31.4 0.4 0.92 9.4 0.1 4.3 2 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 EDO02859.1 - 1.4e-05 25.5 0.2 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO02859.1 - 1.5e-05 25.0 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EDO02859.1 - 2.2e-05 25.2 0.1 0.51 11.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EDO02859.1 - 2.8e-05 23.4 1.1 0.63 9.2 0.0 4.4 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EDO02859.1 - 7.3e-05 22.0 0.1 0.38 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDO02859.1 - 0.00026 20.9 0.5 0.078 12.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDO02859.1 - 0.00041 20.6 0.0 0.53 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDO02859.1 - 0.00065 19.8 0.2 2.2 8.4 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDO02859.1 - 0.00097 19.0 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDO02859.1 - 0.00099 18.8 0.5 1.2 8.8 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EDO02859.1 - 0.0011 18.4 0.6 1.2 8.4 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain T2SE PF00437.15 EDO02859.1 - 0.0025 16.7 0.0 0.087 11.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EDO02859.1 - 0.0055 16.1 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDO02859.1 - 0.01 15.6 1.7 0.071 12.9 0.0 2.6 3 0 0 3 3 2 0 Dynamin family ATP_bind_1 PF03029.12 EDO02859.1 - 0.018 14.6 0.2 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EDO02859.1 - 0.019 15.4 0.4 0.9 10.0 0.1 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EDO02859.1 - 0.032 13.6 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EDO02859.1 - 0.087 13.0 0.1 7.1 6.8 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.7 EDO02859.1 - 0.087 11.9 0.0 12 4.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 EDO02859.1 - 0.089 12.2 0.4 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EDO02859.1 - 0.12 11.8 0.1 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 EDO02859.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF3455 PF11937.3 EDO02860.1 - 6.9e-39 133.6 0.1 8.9e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Imm35 PF15581.1 EDO02862.1 - 0.025 14.5 0.2 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 35 HMG_box PF00505.14 EDO02863.1 - 5.6e-17 61.7 0.1 8.2e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO02863.1 - 0.00023 21.4 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain TIP49 PF06068.8 EDO02864.1 - 1.1e-189 630.2 0.9 1.2e-189 630.0 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EDO02864.1 - 1.8e-11 44.3 0.2 4.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO02864.1 - 8.8e-10 38.0 2.3 1.4e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO02864.1 - 1.8e-05 24.8 0.1 0.12 12.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO02864.1 - 4.6e-05 23.4 0.0 0.0018 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EDO02864.1 - 0.00014 21.5 0.1 0.00045 19.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDO02864.1 - 0.00029 20.8 0.1 0.00056 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO02864.1 - 0.00051 19.1 0.0 0.0013 17.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EDO02864.1 - 0.0006 19.2 0.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDO02864.1 - 0.00098 18.8 0.1 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDO02864.1 - 0.0012 18.3 0.1 0.87 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EDO02864.1 - 0.0044 16.4 0.3 0.013 14.8 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO02864.1 - 0.0048 16.0 0.0 0.23 10.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDO02864.1 - 0.0078 16.1 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EDO02864.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EDO02864.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.1 EDO02864.1 - 0.015 15.6 0.4 0.039 14.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDO02864.1 - 0.019 14.1 0.4 0.083 11.9 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.1 EDO02864.1 - 0.025 15.3 0.0 0.073 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EDO02864.1 - 0.038 12.8 0.2 0.11 11.3 0.1 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein PIF1 PF05970.9 EDO02864.1 - 0.09 11.7 0.0 6 5.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UPF0079 PF02367.12 EDO02864.1 - 0.12 11.9 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EDO02864.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain WD40 PF00400.27 EDO02865.1 - 8e-27 92.1 19.0 3.8e-06 26.5 0.0 10.2 11 0 0 11 11 11 5 WD domain, G-beta repeat Neugrin PF06413.6 EDO02866.1 - 2.3e-10 40.7 2.9 5.4e-10 39.4 0.4 2.3 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 EDO02866.1 - 1.1e-05 25.4 0.4 1.1e-05 25.4 0.3 2.6 3 0 0 3 3 3 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EDO02866.1 - 0.0044 17.1 1.4 0.055 13.6 0.1 2.9 2 1 0 2 2 2 1 Winged helix-turn helix Sof1 PF04158.9 EDO02866.1 - 0.067 13.2 0.2 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Sof1-like domain DUF2236 PF09995.4 EDO02867.1 - 1.4e-32 112.9 0.1 2.5e-32 112.0 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) TRAPPC9-Trs120 PF08626.6 EDO02867.1 - 0.0023 15.3 0.0 0.0032 14.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Calcipressin PF04847.7 EDO02868.1 - 2.5e-49 167.3 0.5 4.1e-49 166.6 0.4 1.3 1 1 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EDO02868.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RNA_pol_A_bac PF01000.21 EDO02869.1 - 4.4e-31 107.3 0.0 7.1e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO02869.1 - 5e-16 57.5 0.0 6.3e-16 57.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1049 PF06305.6 EDO02871.1 - 0.31 10.5 0.9 0.47 9.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Reprolysin_5 PF13688.1 EDO02872.1 - 2.1e-24 86.5 1.0 2.1e-24 86.5 0.7 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EDO02872.1 - 1.4e-17 63.8 0.2 1.9e-17 63.5 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EDO02872.1 - 1.3e-12 48.0 0.1 2e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EDO02872.1 - 8.6e-05 23.0 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like AMP-binding PF00501.23 EDO02873.1 - 3.8e-28 98.0 0.0 4.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1967 PF09269.6 EDO02873.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) IMS PF00817.15 EDO02873.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family AMP-binding PF00501.23 EDO02874.1 - 3.8e-91 305.5 0.3 4.7e-91 305.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO02874.1 - 9.2e-23 80.9 0.1 4.3e-20 72.4 0.1 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain tRNA-synt_2d PF01409.15 EDO02877.1 - 4.7e-47 160.2 2.3 2.8e-26 92.1 0.0 2.6 2 1 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EDO02877.1 - 2e-25 88.7 0.0 7.9e-25 86.8 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EDO02878.1 - 3.3e-58 193.4 1.1 5e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4316 PF14195.1 EDO02879.1 - 1.3 9.1 3.9 3 7.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) GrpE PF01025.14 EDO02881.1 - 3.8e-47 159.9 6.6 4.8e-47 159.5 4.6 1.1 1 0 0 1 1 1 1 GrpE GMC_oxred_C PF05199.8 EDO02881.1 - 0.073 13.3 0.2 0.18 12.0 0.0 1.9 1 1 1 2 2 2 0 GMC oxidoreductase VIT_2 PF13757.1 EDO02881.1 - 0.15 11.5 0.4 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain TPD52 PF04201.10 EDO02881.1 - 0.28 10.9 6.4 0.12 12.0 2.9 1.5 1 1 1 2 2 2 0 Tumour protein D52 family zf-MYND PF01753.13 EDO02883.1 - 0.039 13.8 5.8 0.088 12.6 4.0 1.6 1 0 0 1 1 1 0 MYND finger KIAA1328 PF15369.1 EDO02883.1 - 6.7 6.4 9.9 13 5.4 6.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 KH_1 PF00013.24 EDO02884.1 - 4.8e-40 135.0 16.2 4.5e-14 51.8 1.0 3.5 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EDO02884.1 - 5.2e-30 102.5 14.4 3.3e-10 39.3 1.1 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDO02884.1 - 3.8e-11 42.3 5.9 0.015 14.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDO02884.1 - 5.2e-09 35.6 4.0 0.14 11.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDO02884.1 - 4e-05 23.3 3.9 0.98 9.2 0.0 4.1 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.1 EDO02884.1 - 0.22 10.8 0.0 7.8 5.8 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator K_channel_TID PF07941.6 EDO02884.1 - 0.76 10.0 7.9 0.19 11.9 1.5 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FAD_binding_3 PF01494.14 EDO02886.1 - 4e-15 55.7 0.3 2.1e-08 33.6 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EDO02886.1 - 1.2e-05 25.3 0.0 3.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO02886.1 - 1.3e-05 25.1 0.2 2.6e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO02886.1 - 2.3e-05 23.4 0.1 3.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDO02886.1 - 0.00029 19.8 0.9 0.00066 18.6 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO02886.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDO02886.1 - 0.0048 15.5 0.2 0.12 10.9 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EDO02886.1 - 0.016 14.0 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EDO02886.1 - 0.019 14.7 0.0 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EDO02886.1 - 0.024 14.0 0.3 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EDO02886.1 - 0.03 12.8 0.5 0.048 12.1 0.3 1.4 1 1 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EDO02886.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EDO02886.1 - 0.095 11.7 0.2 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDO02886.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_63 PF03200.11 EDO02887.1 - 7.2e-10 37.3 1.1 1.2e-06 26.7 0.1 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase OSCP PF00213.13 EDO02888.1 - 3e-45 154.1 2.2 3.6e-45 153.9 1.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit RPAP3_C PF13877.1 EDO02888.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Mob1_phocein PF03637.12 EDO02889.1 - 1.7e-72 242.7 0.0 2.2e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.5 EDO02890.1 - 3.4e-87 293.2 0.0 1.5e-70 238.3 0.0 2.9 2 1 1 3 3 3 2 Rgp1 Glyco_hydro_3 PF00933.16 EDO02891.1 - 5.2e-88 294.8 0.0 7.2e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDO02891.1 - 4.1e-48 163.8 0.0 9.6e-48 162.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDO02891.1 - 1.6e-23 82.4 0.0 3.4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 EDO02892.1 - 4.8e-33 114.3 43.8 1e-32 113.2 30.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EDO02893.1 - 1e-44 152.7 36.4 1e-44 152.7 25.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO02893.1 - 1.5e-08 33.7 14.9 1.5e-08 33.7 10.3 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Zn_clus PF00172.13 EDO02894.1 - 3.7e-10 39.5 11.4 5.8e-10 38.9 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2938 PF11158.3 EDO02896.1 - 0.029 13.7 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) PQQ_3 PF13570.1 EDO02897.1 - 0.22 11.8 0.1 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 PQQ-like domain ApoB100_C PF12491.3 EDO02898.1 - 0.1 12.2 0.8 0.14 11.7 0.6 1.2 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal UAF_Rrn10 PF05234.6 EDO02899.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 EDO02900.1 - 2.8e-28 96.7 19.4 3e-10 39.5 1.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO02900.1 - 0.00022 20.1 0.1 3.1 6.4 0.0 3.7 1 1 3 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 EDO02900.1 - 0.12 10.4 0.3 3 5.8 0.2 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 adh_short PF00106.20 EDO02901.1 - 6e-26 91.3 0.0 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO02901.1 - 2.5e-21 76.5 0.2 2.9e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO02901.1 - 1.4e-11 44.4 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDO02901.1 - 0.0077 15.6 0.2 0.03 13.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CENP-H PF05837.7 EDO02901.1 - 0.048 13.8 0.9 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HEM4 PF02602.10 EDO02901.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Med26 PF08711.6 EDO02901.1 - 0.12 11.9 0.2 4 7.0 0.2 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Ribosomal_L44 PF00935.14 EDO02906.1 - 2.3e-35 120.4 11.6 3.4e-35 119.8 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 p450 PF00067.17 EDO02907.1 - 2.1e-51 174.9 0.0 3.7e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.23 EDO02909.1 - 2.8e-13 49.4 0.0 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.1 EDO02910.1 - 6.4e-11 42.0 1.1 0.00052 19.9 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO02910.1 - 1.9e-05 24.0 1.7 5.2 7.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO02910.1 - 0.00023 20.8 7.9 0.16 11.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO02910.1 - 0.00023 20.7 3.4 3.5 7.3 0.0 3.7 2 2 1 3 3 3 3 TPR repeat RPN7 PF10602.4 EDO02910.1 - 0.001 18.4 0.1 1.2 8.5 0.0 3.2 4 0 0 4 4 4 2 26S proteasome subunit RPN7 TPR_16 PF13432.1 EDO02910.1 - 0.0067 17.0 0.3 1.7 9.4 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 EDO02910.1 - 0.012 14.7 0.5 12 4.9 0.0 3.2 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 EDO02910.1 - 0.02 14.7 1.1 16 5.6 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02910.1 - 0.2 12.4 2.0 81 4.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO02910.1 - 0.36 10.5 6.8 3.2 7.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EDO02911.1 - 0.00052 20.2 14.3 0.03 14.6 0.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO02911.1 - 0.0012 19.0 16.4 0.073 13.4 0.2 4.9 4 1 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EDO02911.1 - 0.0086 16.2 3.8 0.076 13.2 0.3 3.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-TRAF PF02176.13 EDO02911.1 - 0.074 13.4 0.3 0.2 12.0 0.2 1.8 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EDO02911.1 - 3.1 8.0 5.3 16 5.8 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_jaz PF12171.3 EDO02912.1 - 0.013 15.6 0.4 0.013 15.6 0.3 6.7 7 1 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDO02912.1 - 0.06 13.7 48.3 0.27 11.6 1.3 8.1 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-met PF12874.2 EDO02912.1 - 0.065 13.4 0.5 0.065 13.4 0.4 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type GutM PF06923.6 EDO02916.1 - 0.04 13.5 0.2 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) p450 PF00067.17 EDO02917.1 - 8.4e-42 143.2 0.0 1.9e-41 142.1 0.0 1.4 1 1 1 2 2 2 1 Cytochrome P450 Pal1 PF08316.6 EDO02918.1 - 2.2e-50 170.7 0.9 5.7e-50 169.4 0.6 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein Med31 PF05669.7 EDO02921.1 - 1.1e-30 105.3 0.0 1.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 EDO02922.1 - 1e-12 47.4 2.7 1e-12 47.4 1.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EDO02922.1 - 0.0025 17.4 6.8 0.45 10.2 0.1 3.2 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EDO02922.1 - 0.2 11.3 1.1 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like IBR PF01485.16 EDO02922.1 - 1.1 9.2 7.5 1.9 8.4 0.8 2.5 2 2 0 2 2 2 0 IBR domain Ank_2 PF12796.2 EDO02923.1 - 1.4e-09 38.1 0.0 3e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO02923.1 - 5.3e-08 33.1 0.0 1.5e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EDO02923.1 - 8.9e-08 31.5 0.1 0.00012 21.6 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDO02923.1 - 1.4e-07 31.5 0.0 0.026 14.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO02923.1 - 3.6e-05 23.5 0.0 0.067 13.4 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat DRY_EERY PF09750.4 EDO02924.1 - 0.85 9.7 5.5 2.5 8.2 3.8 1.8 1 1 0 1 1 1 0 Alternative splicing regulator Thaumatin PF00314.12 EDO02926.1 - 3.5e-73 245.5 2.7 4.6e-73 245.1 1.9 1.2 1 0 0 1 1 1 1 Thaumatin family DUF1987 PF09345.5 EDO02926.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) HSP70 PF00012.15 EDO02927.1 - 1.6e-11 42.8 0.3 6.9e-10 37.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EDO02927.1 - 0.0015 18.1 0.1 0.0034 16.9 0.1 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EDO02927.1 - 0.02 13.4 0.1 0.17 10.4 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_1 PF00349.16 EDO02930.1 - 3.1e-66 222.6 0.0 6e-66 221.7 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EDO02930.1 - 2.4e-62 210.3 2.4 1.4e-46 158.7 0.1 2.4 1 1 1 2 2 2 2 Hexokinase SUR7 PF06687.7 EDO02932.1 - 0.95 8.9 4.0 2 7.9 2.7 1.7 1 1 0 1 1 1 0 SUR7/PalI family RNase_PH PF01138.16 EDO02934.1 - 4.6e-20 72.2 0.0 8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO02934.1 - 8.3e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 C1_1 PF00130.17 EDO02935.1 - 0.044 13.5 0.4 0.045 13.4 0.3 1.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF35_N PF12172.3 EDO02935.1 - 0.054 13.4 0.4 0.082 12.8 0.3 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NAD_binding_6 PF08030.7 EDO02937.1 - 2.1e-16 60.1 0.0 1.5e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDO02937.1 - 3.4e-13 49.3 0.0 6.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDO02937.1 - 1.1e-05 25.5 1.1 2.3e-05 24.5 0.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EDO02937.1 - 0.0072 16.8 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain GDI PF00996.13 EDO02938.1 - 1.4e-43 148.8 0.0 1.9e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MPC PF03650.8 EDO02940.1 - 1.5e-41 141.0 1.1 2.2e-41 140.5 0.3 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 EDO02941.1 - 8.8e-15 54.1 0.0 1.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Redoxin PF08534.5 EDO02942.1 - 5.3e-36 123.3 0.0 5.7e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO02942.1 - 5.3e-12 45.5 0.0 6.9e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 EDO02943.1 - 9.1e-54 181.1 7.5 1.1e-53 180.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EDO02943.1 - 3e-05 24.3 1.2 4.2e-05 23.8 0.8 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EDO02943.1 - 0.00029 21.0 0.1 0.0004 20.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3648 PF12364.3 EDO02943.1 - 0.044 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) SnoaL PF07366.7 EDO02943.1 - 0.065 12.8 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Erythro_esteras PF05139.9 EDO02944.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Erythromycin esterase WRKY PF03106.10 EDO02945.1 - 0.079 12.8 1.7 0.14 12.0 1.2 1.4 1 0 0 1 1 1 0 WRKY DNA -binding domain Dioxygenase_C PF00775.16 EDO02947.1 - 1.3e-53 181.0 0.0 1.9e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EDO02947.1 - 4.3e-16 58.6 0.0 8.5e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EDO02947.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain A_deamin PF02137.13 EDO02948.1 - 1.4e-61 208.7 0.0 1.8e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain PHD PF00628.24 EDO02949.1 - 1.2e-09 37.6 10.1 2.4e-09 36.7 7.0 1.5 1 0 0 1 1 1 1 PHD-finger Bac_chlorC PF02043.12 EDO02951.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Lipase_GDSL_2 PF13472.1 EDO02957.1 - 9.4e-08 32.3 0.6 3.6e-07 30.4 0.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDO02957.1 - 0.00022 21.1 9.3 0.0014 18.5 6.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2365 PF10157.4 EDO02958.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Entericidin PF08085.6 EDO02959.1 - 0.014 15.1 0.3 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Entericidin EcnA/B family Sel1 PF08238.7 EDO02960.1 - 8.3e-25 86.6 31.3 6.2e-06 26.6 0.1 8.0 6 1 1 7 7 7 6 Sel1 repeat CBP4 PF07960.6 EDO02961.1 - 2.1e-37 127.6 0.8 2.4e-37 127.3 0.5 1.0 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.17 EDO02961.1 - 0.031 14.2 8.3 0.16 11.9 5.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FliT PF05400.8 EDO02961.1 - 0.035 14.5 0.3 0.057 13.8 0.2 1.3 1 0 0 1 1 1 0 Flagellar protein FliT DUF3340 PF11818.3 EDO02961.1 - 0.051 13.5 4.2 0.062 13.2 2.9 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF1221 PF06760.6 EDO02961.1 - 0.053 12.7 0.4 0.063 12.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DUF739 PF05339.6 EDO02961.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF739) RNase_H2-Ydr279 PF09468.5 EDO02961.1 - 0.086 12.0 1.6 0.097 11.8 1.1 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2870 PF11069.3 EDO02961.1 - 0.55 10.2 4.8 0.94 9.5 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) TPR_11 PF13414.1 EDO02963.1 - 2.6e-52 174.3 37.4 3.2e-14 52.3 0.4 6.9 3 3 4 8 8 8 8 TPR repeat TPR_1 PF00515.23 EDO02963.1 - 1.4e-39 132.1 28.3 2.1e-05 23.9 0.1 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EDO02963.1 - 2.8e-37 123.6 24.7 6.7e-06 25.6 0.2 11.1 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EDO02963.1 - 1.4e-25 89.3 15.3 1.1e-05 25.9 0.9 6.7 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDO02963.1 - 3.6e-25 87.7 26.8 1.3e-09 37.8 0.0 7.5 2 2 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EDO02963.1 - 2.3e-22 77.2 8.5 0.0049 16.9 0.0 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDO02963.1 - 1.7e-18 64.9 21.3 0.00029 20.4 0.5 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO02963.1 - 3.8e-13 48.8 18.0 0.034 14.7 0.2 9.0 4 3 6 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDO02963.1 - 3.3e-12 45.2 20.1 0.017 14.9 0.1 9.2 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO02963.1 - 4.3e-12 46.2 23.5 3.8e-06 27.1 0.2 7.1 5 2 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDO02963.1 - 7.5e-12 44.9 12.6 9.3e-05 22.2 0.6 6.8 4 2 3 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EDO02963.1 - 5.5e-10 39.2 19.4 0.0008 19.5 0.1 5.7 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDO02963.1 - 7.7e-05 22.4 12.0 1 9.3 0.0 6.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO02963.1 - 0.0033 17.7 25.0 4.4 7.9 0.3 8.7 8 0 0 8 8 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDO02963.1 - 0.016 14.4 22.0 0.42 9.8 0.2 7.1 7 0 0 7 7 7 0 SHNi-TPR MAS20 PF02064.10 EDO02963.1 - 0.026 14.4 0.7 44 3.9 0.0 3.8 3 0 0 3 3 3 0 MAS20 protein import receptor Phage_Coat_B PF05356.6 EDO02963.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage Coat protein B Sel1 PF08238.7 EDO02963.1 - 1.9 9.2 8.9 1.4 9.6 0.1 4.4 4 0 0 4 4 3 0 Sel1 repeat Aminotran_4 PF01063.14 EDO02967.1 - 1.3e-16 60.7 0.0 1.7e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EDO02968.1 - 3.4e-70 236.1 0.0 4.1e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO02968.1 - 2.8e-31 108.5 0.0 3.7e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO02968.1 - 0.019 14.7 0.8 0.068 12.8 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO02968.1 - 0.065 12.2 0.1 0.2 10.7 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLAT PF01477.18 EDO02968.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 PLAT/LH2 domain tRNA-synt_1b PF00579.20 EDO02970.1 - 1.3e-21 76.9 0.0 4.5e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Tmemb_cc2 PF10267.4 EDO02970.1 - 0.0021 16.6 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein PRELI PF04707.9 EDO02971.1 - 3.1e-22 78.8 0.5 1.9e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Peptidase_S10 PF00450.17 EDO02972.1 - 3.5e-90 303.1 0.5 4.9e-90 302.6 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DDE_1 PF03184.14 EDO02973.1 - 1.6e-52 177.7 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO02973.1 - 1.3e-10 40.6 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO02973.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO02973.1 - 4.3e-07 29.6 0.8 1.8e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO02973.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle HTH_psq PF05225.11 EDO02974.1 - 7.7e-10 38.1 0.1 1.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO02974.1 - 9.8e-07 28.4 1.6 1.1e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain NUMOD1 PF07453.8 EDO02974.1 - 0.016 15.0 0.4 0.86 9.5 0.0 3.0 3 0 0 3 3 3 0 NUMOD1 domain HTH_28 PF13518.1 EDO02974.1 - 0.02 14.8 0.5 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EDO02974.1 - 0.051 13.2 0.5 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.1 EDO02974.1 - 0.069 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 EDO02974.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Mfp-3 PF04202.8 EDO02975.1 - 0.02 15.0 0.2 0.06 13.5 0.1 1.7 1 0 0 1 1 1 0 Foot protein 3 LysM PF01476.15 EDO02976.1 - 8.1e-14 51.2 4.0 0.021 14.6 0.0 5.5 5 0 0 5 5 5 5 LysM domain Glyco_hydro_18 PF00704.23 EDO02977.1 - 4.3e-78 263.1 0.3 6.1e-78 262.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EDO02977.1 - 9.6e-09 35.0 12.2 9.6e-09 35.0 8.5 5.1 6 0 0 6 6 6 2 Chitin recognition protein Filament PF00038.16 EDO02978.1 - 0.00045 19.7 7.9 0.016 14.6 0.0 2.6 1 1 1 2 2 2 1 Intermediate filament protein EzrA PF06160.7 EDO02978.1 - 0.0052 15.0 0.2 0.069 11.3 0.0 2.0 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA DivIC PF04977.10 EDO02978.1 - 0.0083 15.5 1.4 3.2 7.3 0.0 3.8 2 1 0 3 3 3 1 Septum formation initiator Fez1 PF06818.10 EDO02978.1 - 0.068 13.1 15.0 0.032 14.2 2.9 2.7 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.3 EDO02978.1 - 0.097 12.4 1.2 4.4 7.1 0.0 3.3 3 1 0 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.3 EDO02978.1 - 0.12 12.0 5.4 1.4 8.6 0.3 3.6 2 1 3 5 5 5 0 Protein of unknown function (DUF2730) DUF1664 PF07889.7 EDO02978.1 - 0.15 11.9 0.3 7.2 6.4 0.0 3.1 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EDO02978.1 - 0.15 11.8 7.1 8.5 6.1 0.0 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EDO02978.1 - 0.16 11.8 11.4 3 7.6 0.5 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.1 EDO02978.1 - 0.16 11.2 3.5 2.5 7.3 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) COMP PF11598.3 EDO02978.1 - 0.21 11.6 8.1 30 4.7 0.0 5.3 2 1 3 5 5 5 0 Cartilage oligomeric matrix protein CENP-Q PF13094.1 EDO02978.1 - 0.21 11.5 4.8 0.14 12.1 0.5 2.5 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2968 PF11180.3 EDO02978.1 - 0.22 10.8 6.6 2 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) COG2 PF06148.6 EDO02978.1 - 0.44 10.4 2.9 16 5.4 0.1 3.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 EDO02978.1 - 0.54 9.1 4.8 11 4.8 3.1 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Metal_resist PF13801.1 EDO02978.1 - 0.57 10.1 17.8 6.9 6.6 0.1 4.5 1 1 3 4 4 4 0 Heavy-metal resistance IncA PF04156.9 EDO02978.1 - 0.71 9.4 8.1 4.2 6.9 0.8 2.8 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 EDO02978.1 - 1 9.7 6.2 2.5 8.4 0.3 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 EDO02978.1 - 2.4 6.3 11.3 3.1 6.0 6.6 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TSC22 PF01166.13 EDO02978.1 - 4.5 7.3 8.0 18 5.3 0.0 4.2 3 2 3 6 6 6 0 TSC-22/dip/bun family Sugar_tr PF00083.19 EDO02979.1 - 8.7e-122 406.9 25.1 1e-121 406.7 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO02979.1 - 1.7e-22 79.6 26.6 1.7e-22 79.6 18.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily EBP PF05241.7 EDO02979.1 - 0.019 13.9 7.0 0.039 12.9 4.9 1.5 1 0 0 1 1 1 0 Emopamil binding protein TPR_19 PF14559.1 EDO02979.1 - 0.088 13.1 0.3 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3154 PF11351.3 EDO02979.1 - 0.95 9.2 3.1 0.69 9.6 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) But2 PF09792.4 EDO02980.1 - 2.5e-35 121.2 1.1 2.5e-35 121.2 0.8 2.4 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain Herpes_capsid PF06112.6 EDO02980.1 - 5.2 7.1 9.6 1.1 9.3 4.2 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Abhydrolase_2 PF02230.11 EDO02981.1 - 1.3e-45 155.5 1.7 9.4e-20 70.9 0.1 4.7 4 1 0 4 4 4 4 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDO02981.1 - 6.4e-14 51.9 0.0 1.1e-05 25.1 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO02981.1 - 7.2e-12 45.6 0.0 1.9e-06 27.9 0.0 3.6 2 2 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO02981.1 - 0.00021 20.5 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EDO02981.1 - 0.0013 18.3 0.0 0.5 9.8 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 EDO02981.1 - 0.0014 17.8 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase CobT PF06213.7 EDO02981.1 - 0.02 14.0 2.1 0.027 13.6 1.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT APG5 PF04106.7 EDO02982.1 - 6.2e-48 162.8 0.0 1.5e-46 158.3 0.0 2.0 2 0 0 2 2 2 2 Autophagy protein Apg5 ACT_7 PF13840.1 EDO02983.1 - 0.013 14.9 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain DUF4131 PF13567.1 EDO02983.1 - 8.8 5.7 9.3 0.84 9.0 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) 4HBT_2 PF13279.1 EDO02984.1 - 1.3e-05 25.6 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 EDO02986.1 - 0.009 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_trans_N PF14510.1 EDO02986.1 - 0.077 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal APG6 PF04111.7 EDO02987.1 - 0.14 11.1 5.7 0.19 10.7 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tox-ODYAM1 PF15642.1 EDO02987.1 - 0.27 9.8 2.0 0.34 9.5 1.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Zn_clus PF00172.13 EDO02987.1 - 0.43 10.5 10.3 2 8.3 7.3 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain gag-asp_proteas PF13975.1 EDO02988.1 - 5e-15 55.0 0.1 1.1e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO02988.1 - 4.3e-10 39.9 0.0 8.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDO02988.1 - 2.6e-09 37.0 1.3 1.4e-08 34.7 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.21 EDO02988.1 - 2.9e-09 37.0 0.0 8.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 EDO02988.1 - 1.8e-06 27.5 2.6 3.2e-06 26.7 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 EDO02988.1 - 2.7e-06 26.9 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EDO02988.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDO02988.1 - 0.0041 16.6 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_5 PF14787.1 EDO02988.1 - 0.1 12.0 9.4 0.025 14.0 4.1 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DDE_1 PF03184.14 EDO02989.1 - 8.3e-18 64.3 0.0 3.2e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO02989.1 - 1.4e-06 27.9 0.1 4.5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ZZ PF00569.12 EDO02990.1 - 8.8e-17 60.3 55.5 5.8e-06 25.7 4.6 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type ODC_AZ PF02100.12 EDO02991.1 - 6e-29 99.7 0.0 9.2e-29 99.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 EDO02993.1 - 2e-22 79.0 0.0 4.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DWNN PF08783.6 EDO02997.1 - 6.6e-30 102.8 0.0 1.4e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EDO02997.1 - 0.00024 20.5 3.7 0.00082 18.8 2.6 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EDO02997.1 - 0.00092 19.0 1.3 0.0018 18.1 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 EDO02997.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 EDO02997.1 - 0.011 15.5 1.6 0.019 14.7 1.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCHC_3 PF13917.1 EDO02997.1 - 0.04 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_5 PF14634.1 EDO02997.1 - 0.41 10.4 9.7 0.055 13.1 3.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EDO02997.1 - 0.46 10.1 7.3 1 8.9 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EDO02997.1 - 0.51 10.4 13.5 0.05 13.6 5.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO02997.1 - 0.7 9.5 7.8 1.4 8.5 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO02997.1 - 1.6 8.7 8.1 5 7.0 5.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Mito_fiss_reg PF05308.6 EDO03000.1 - 0.33 10.2 1.9 0.35 10.2 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DAO PF01266.19 EDO03002.1 - 2.5e-50 171.3 0.0 3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO03002.1 - 0.00013 21.8 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO03002.1 - 0.00024 21.0 0.2 0.00068 19.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO03002.1 - 0.00086 18.2 0.1 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EDO03002.1 - 0.0022 18.0 0.0 0.093 12.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDO03002.1 - 0.0028 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EDO03002.1 - 0.0046 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EDO03002.1 - 0.013 15.3 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EDO03002.1 - 0.042 12.8 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EDO03002.1 - 0.1 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Macoilin PF09726.4 EDO03004.1 - 0.45 8.7 3.7 0.61 8.2 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein PEARLI-4 PF05278.7 EDO03004.1 - 2.3 7.5 7.1 3.7 6.8 4.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Helicase_C PF00271.26 EDO03005.1 - 4.7e-14 52.0 0.0 1.9e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO03005.1 - 6.9e-10 38.6 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO03005.1 - 5.3e-06 26.6 0.1 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO03005.1 - 0.00032 19.6 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 EDO03005.1 - 0.0037 16.9 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 EDO03005.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family OB_NTP_bind PF07717.11 EDO03006.1 - 9.6e-10 38.3 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Exo_endo_phos_2 PF14529.1 EDO03007.1 - 2.8e-21 75.3 2.8 3.6e-21 74.9 1.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDO03007.1 - 1.3e-19 70.4 0.1 3e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO03007.1 - 1.6e-14 54.3 0.0 4.9e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDO03007.1 - 8e-05 22.6 0.6 0.00013 21.9 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EDO03007.1 - 0.00028 21.1 0.9 0.057 13.7 0.0 3.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase WD40 PF00400.27 EDO03008.1 - 1.6e-179 576.2 47.2 4.7e-15 54.7 0.0 12.5 13 0 0 13 13 13 12 WD domain, G-beta repeat PD40 PF07676.7 EDO03008.1 - 6.7e-14 51.1 24.9 1.4 8.7 0.0 12.0 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EDO03008.1 - 6.2e-10 37.9 0.0 9.7 4.2 0.0 9.0 1 1 10 12 12 12 2 Protein of unknown function (DUF3312) DUF1258 PF06869.7 EDO03008.1 - 4.7e-09 35.7 1.5 4.5 6.2 0.0 7.7 1 1 6 9 9 9 3 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 EDO03008.1 - 4.6e-08 31.7 2.4 0.075 11.3 0.1 5.3 1 1 7 8 8 8 5 Cytochrome D1 heme domain Nbas_N PF15492.1 EDO03008.1 - 1.2e-07 31.1 16.9 4.3 6.3 0.0 10.8 1 1 11 12 12 12 1 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.10 EDO03008.1 - 0.0043 15.6 11.4 8.9 4.7 0.1 8.0 2 2 6 9 9 9 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Rax2 PF12768.2 EDO03008.1 - 0.018 14.2 4.5 9.4 5.3 0.0 4.2 1 1 3 4 4 4 0 Cortical protein marker for cell polarity IKI3 PF04762.7 EDO03008.1 - 0.019 12.8 0.7 4.2 5.0 0.0 3.8 2 2 2 5 5 5 0 IKI3 family Lipocalin_3 PF12702.2 EDO03008.1 - 0.11 12.5 9.8 41 4.2 0.0 5.7 2 2 4 7 7 7 0 Lipocalin-like Thioredox_DsbH PF03190.10 EDO03008.1 - 0.25 11.0 0.9 1.6e+02 1.9 0.0 4.4 4 1 2 6 6 6 0 Protein of unknown function, DUF255 HET PF06985.6 EDO03009.1 - 6.3e-22 78.2 8.0 6.2e-20 71.7 5.5 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EDO03009.1 - 7.8e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EDO03009.1 - 1.8e-06 28.0 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EDO03009.1 - 0.0001 21.4 0.5 0.00079 18.5 0.3 2.0 1 1 1 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EDO03009.1 - 0.0036 17.0 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EDO03009.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EDO03009.1 - 0.091 11.5 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EDO03009.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EDO03009.1 - 0.12 12.5 0.0 0.5 10.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HAD_2 PF13419.1 EDO03010.1 - 3.8e-23 82.5 0.4 1.6e-21 77.2 0.2 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 EDO03010.1 - 0.0059 17.0 0.2 0.39 11.1 0.0 2.8 3 0 0 3 3 3 1 Prenyltransferase-like Hydrolase_like PF13242.1 EDO03010.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans PF00432.16 EDO03010.1 - 0.041 13.4 1.2 0.27 10.8 0.3 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Hydrolase PF00702.21 EDO03010.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase eRF1_3 PF03465.10 EDO03010.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 3 Glyco_hydro_57 PF03065.10 EDO03010.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 RCR PF12273.3 EDO03012.1 - 3.4e-13 50.2 2.1 4.6e-13 49.8 1.5 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.6 EDO03012.1 - 0.00035 20.1 0.4 0.00056 19.5 0.3 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein Shisa PF13908.1 EDO03012.1 - 0.0033 17.6 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.3 EDO03012.1 - 0.0085 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 Ion_trans_2 PF07885.11 EDO03012.1 - 0.023 14.3 0.4 0.036 13.7 0.3 1.2 1 0 0 1 1 1 0 Ion channel TMEM51 PF15345.1 EDO03012.1 - 0.029 14.0 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.11 EDO03012.1 - 0.032 12.4 0.0 0.038 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Gypsy PF07253.6 EDO03012.1 - 0.067 11.4 0.0 0.075 11.3 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein SCIMP PF15050.1 EDO03012.1 - 0.088 12.7 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein EphA2_TM PF14575.1 EDO03012.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AA_permease_C PF13906.1 EDO03012.1 - 0.16 11.8 1.8 0.27 11.1 1.2 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease p450 PF00067.17 EDO03013.1 - 1.1e-41 142.8 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDO03014.1 - 9.6e-58 195.8 0.0 1.3e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CAAP1 PF15335.1 EDO03015.1 - 0.04 14.1 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Tannase PF07519.6 EDO03016.1 - 4.3e-103 345.5 2.5 5.7e-103 345.1 1.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase WSC PF01822.14 EDO03017.1 - 2.1e-33 114.0 38.6 5.1e-19 67.9 6.0 3.1 3 0 0 3 3 3 2 WSC domain PQQ_3 PF13570.1 EDO03017.1 - 4.3e-05 23.6 1.4 0.018 15.2 0.0 3.9 3 0 0 3 3 3 2 PQQ-like domain DNA_ligase_OB PF03120.11 EDO03017.1 - 1.6 8.4 4.6 9.9 5.9 0.2 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase OB-fold domain Methyltransf_23 PF13489.1 EDO03018.1 - 6.1e-24 84.5 0.0 8.8e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO03018.1 - 7.1e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03018.1 - 7.4e-11 42.6 0.0 1.2e-09 38.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03018.1 - 6.7e-10 38.7 0.0 1.4e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03018.1 - 5.3e-08 33.2 0.0 2.3e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03018.1 - 2.9e-06 27.5 0.0 2.2e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO03018.1 - 6e-06 26.2 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDO03018.1 - 7.4e-05 21.8 0.0 0.00035 19.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EDO03018.1 - 0.00015 21.1 0.0 0.0024 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EDO03018.1 - 0.00029 20.8 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EDO03018.1 - 0.00033 19.8 0.0 0.0013 17.8 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EDO03018.1 - 0.0013 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EDO03018.1 - 0.0079 15.3 0.0 0.045 12.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EDO03018.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EDO03018.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 EDO03018.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) vMSA PF00695.14 EDO03020.1 - 0.0082 15.3 0.2 0.009 15.2 0.1 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus DUF1183 PF06682.7 EDO03020.1 - 0.61 9.6 2.9 0.73 9.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MAD PF05557.8 EDO03021.1 - 0.033 12.3 0.4 0.034 12.2 0.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF342 PF03961.8 EDO03022.1 - 0.013 13.9 0.9 0.015 13.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EDO03022.1 - 0.12 12.1 2.9 0.15 11.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EDO03022.1 - 0.94 9.0 7.9 1.2 8.7 5.5 1.1 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 EDO03022.1 - 1.1 9.5 6.9 1.3 9.3 3.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF4404 PF14357.1 EDO03022.1 - 3.9 7.9 8.3 6.2 7.3 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Ribosomal_L7Ae PF01248.21 EDO03024.1 - 1.4e-25 88.6 0.0 1.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EDO03025.1 - 6.4e-31 106.8 0.1 8.4e-31 106.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF605 PF04652.11 EDO03029.1 - 0.075 12.4 9.2 0.075 12.4 6.4 1.1 1 0 0 1 1 1 0 Vta1 like UvrD-helicase PF00580.16 EDO03030.1 - 4.6e-08 32.7 0.1 0.0064 15.8 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EDO03030.1 - 1.5e-05 24.6 0.0 7.9e-05 22.2 0.0 1.9 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EDO03030.1 - 6e-05 22.7 0.2 0.0003 20.4 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EDO03030.1 - 6.3e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO03030.1 - 6.3e-05 22.5 0.1 0.0003 20.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cas_Cas4 PF01930.12 EDO03030.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EDO03030.1 - 0.00088 18.8 0.0 0.0066 15.9 0.0 2.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Methyltransf_4 PF02390.12 EDO03030.1 - 0.0026 16.8 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UvrD_C_2 PF13538.1 EDO03030.1 - 0.0028 17.7 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EDO03030.1 - 0.0088 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO03030.1 - 0.015 15.4 0.1 0.05 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO03030.1 - 0.078 12.2 0.2 0.25 10.5 0.1 1.8 1 1 0 1 1 1 0 PhoH-like protein Methyltransf_31 PF13847.1 EDO03030.1 - 0.18 11.3 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Herpes_ori_bp PF02399.10 EDO03030.1 - 0.25 9.2 0.0 0.37 8.6 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein NAD_binding_10 PF13460.1 EDO03032.1 - 1.9e-05 24.7 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EDO03032.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EDO03032.1 - 0.037 12.9 0.1 0.093 11.6 0.0 1.7 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EDO03032.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EDO03032.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Uds1 PF15456.1 EDO03033.1 - 8e-36 122.7 1.9 8e-36 122.7 1.3 2.4 3 0 0 3 3 3 1 Up-regulated During Septation Peptidase_M1 PF01433.15 EDO03035.1 - 4.4e-68 230.1 0.0 5.6e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EDO03035.1 - 9e-43 145.3 0.0 1.6e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EDO03035.1 - 3.1e-18 66.0 0.1 5.7e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EDO03035.1 - 0.2 11.6 2.1 1.2 9.1 1.5 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DLH PF01738.13 EDO03037.1 - 7.4e-08 31.9 0.0 9.8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Thioredoxin_8 PF13905.1 EDO03037.1 - 0.093 12.8 0.9 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin-like PLDc_N PF13396.1 EDO03040.1 - 5.3 6.7 6.8 7.8 6.2 4.7 1.1 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal GTP_EFTU PF00009.22 EDO03042.1 - 3.6e-58 196.0 0.0 5.4e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO03042.1 - 1.3e-36 124.6 0.0 3.7e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO03042.1 - 1.4e-15 57.1 3.4 1.4e-15 57.1 2.4 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO03042.1 - 0.00047 20.0 0.3 0.0014 18.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDO03042.1 - 0.002 17.7 1.5 0.002 17.7 1.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PDZ PF00595.19 EDO03042.1 - 0.1 12.7 0.6 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Rotavirus_VP1 PF12289.3 EDO03043.1 - 0.023 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein DUF3366 PF11846.3 EDO03045.1 - 0.059 13.2 0.1 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) Oxysterol_BP PF01237.13 EDO03046.1 - 1.9e-130 434.5 0.1 6.5e-130 432.7 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EDO03046.1 - 3.8e-18 65.6 0.0 1e-10 41.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO03046.1 - 1.7e-17 63.0 0.7 7.3e-10 38.7 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EDO03046.1 - 7.4e-15 53.9 0.3 0.00019 21.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EDO03046.1 - 1e-13 51.4 0.0 1.6e-06 28.4 0.0 3.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO03046.1 - 2e-11 42.9 0.0 0.0042 17.2 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat PH PF00169.24 EDO03046.1 - 2.5e-10 40.5 0.3 4.9e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EDO03046.1 - 1.3e-06 28.3 0.5 3.1e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ATP12 PF07542.6 EDO03047.1 - 1.9e-37 127.8 0.1 3.2e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF3435 PF11917.3 EDO03048.1 - 8.1e-32 110.4 4.1 4.2e-29 101.5 1.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) FlaC_arch PF05377.6 EDO03048.1 - 0.035 13.9 0.3 0.096 12.5 0.2 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) GSH_synth_ATP PF03917.12 EDO03048.1 - 0.079 11.5 1.4 0.11 11.0 1.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain DDE_1 PF03184.14 EDO03049.1 - 1.4e-15 57.0 0.2 2.3e-09 36.7 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease LRR_adjacent PF08191.6 EDO03049.1 - 0.0087 15.7 0.5 0.015 14.9 0.4 1.4 1 0 0 1 1 1 1 LRR adjacent TPR_10 PF13374.1 EDO03050.1 - 8.9e-65 212.9 19.6 1.1e-10 41.0 0.0 7.9 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EDO03050.1 - 5.4e-57 189.6 25.9 6.6e-18 64.4 0.8 5.4 3 1 2 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDO03050.1 - 1.3e-31 106.8 26.2 4.9e-05 22.7 0.1 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 EDO03050.1 - 3.8e-27 91.8 13.9 0.00077 19.0 0.0 7.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EDO03050.1 - 1.5e-22 78.9 34.8 2.4e-07 30.2 1.0 5.7 1 1 5 6 6 6 6 TPR repeat HET PF06985.6 EDO03050.1 - 9.6e-22 77.6 15.8 6.3e-20 71.7 8.1 3.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.12 EDO03050.1 - 7.1e-21 72.3 23.0 0.0043 16.8 0.1 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDO03050.1 - 5.5e-18 63.3 21.8 0.14 12.0 0.2 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO03050.1 - 1.6e-17 62.3 11.9 0.39 11.4 0.0 7.9 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EDO03050.1 - 5.6e-16 57.3 9.8 0.66 10.3 0.0 9.1 7 2 0 7 7 7 5 Tetratricopeptide repeat NB-ARC PF00931.17 EDO03050.1 - 2e-13 49.8 0.2 3.1e-13 49.2 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EDO03050.1 - 2.6e-12 47.0 11.7 0.00084 19.9 0.4 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.9 EDO03050.1 - 7.4e-11 41.4 0.0 15 6.3 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_16 PF13191.1 EDO03050.1 - 6.2e-10 39.3 0.1 2.5e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO03050.1 - 1.5e-06 28.3 0.0 4.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDO03050.1 - 6.5e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase RPN7 PF10602.4 EDO03050.1 - 4.3e-05 22.9 8.7 4.1 6.7 0.0 6.2 1 1 4 6 6 6 1 26S proteasome subunit RPN7 DUF2225 PF09986.4 EDO03050.1 - 0.00044 19.7 4.4 0.0042 16.5 0.1 3.1 2 1 1 3 3 2 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF630 PF04783.7 EDO03050.1 - 0.00048 19.9 6.7 38 4.2 0.0 6.4 6 0 0 6 6 6 0 Protein of unknown function (DUF630) AAA_14 PF13173.1 EDO03050.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain PPR PF01535.15 EDO03050.1 - 0.011 15.7 7.0 32 4.7 0.0 6.4 7 0 0 7 7 6 0 PPR repeat NACHT PF05729.7 EDO03050.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Lectin_N PF03954.9 EDO03050.1 - 0.036 13.4 2.6 30 3.9 0.1 4.5 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain AAA_33 PF13671.1 EDO03050.1 - 0.089 12.6 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_21 PF09976.4 EDO03050.1 - 0.12 12.3 5.5 1.9e+02 1.9 0.0 5.8 5 2 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO03050.1 - 1.4 9.3 18.2 9.2 6.6 1.3 5.4 2 1 5 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO03050.1 - 5.8 7.6 17.2 1.1e+02 3.5 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Pedibin PF08182.6 EDO03050.1 - 6.4 6.3 12.7 1.5e+02 1.9 0.1 5.5 5 0 0 5 5 5 0 Pedibin/Hym-346 family DUF3435 PF11917.3 EDO03051.1 - 9.7e-14 50.9 0.0 1.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.18 EDO03052.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO03052.1 - 0.0024 16.9 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDO03052.1 - 0.0083 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EDO03052.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 EDO03052.1 - 0.062 12.3 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Mito_fiss_reg PF05308.6 EDO03052.1 - 0.25 10.6 3.3 0.38 10.0 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 EDO03054.1 - 6.3e-158 507.7 36.2 2.5e-15 55.6 0.3 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat HET PF06985.6 EDO03054.1 - 2.8e-21 76.1 7.8 1.7e-19 70.3 5.4 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EDO03054.1 - 3.8e-20 72.2 0.0 6.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF1652 PF07865.6 EDO03054.1 - 2.8e-10 39.6 0.0 43 3.8 0.0 9.5 8 2 3 11 11 11 0 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.11 EDO03054.1 - 1.2e-08 33.6 1.9 0.11 10.7 0.0 3.7 2 2 2 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 EDO03054.1 - 2.7e-08 33.2 19.3 46 3.8 0.0 10.5 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 EDO03054.1 - 2.8e-06 26.1 9.8 2.6 6.5 0.0 6.9 2 1 4 7 7 7 5 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.1 EDO03054.1 - 4.9e-06 26.6 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EDO03054.1 - 0.00034 19.7 0.5 0.0018 17.3 0.3 2.0 1 1 1 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EDO03054.1 - 0.0025 17.5 0.1 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EDO03054.1 - 0.028 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Methyltransf_30 PF05430.6 EDO03054.1 - 0.06 13.0 0.0 32 4.2 0.0 3.9 2 1 2 4 4 4 0 S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 EDO03054.1 - 0.22 10.6 0.3 30 3.5 0.0 3.4 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Terminase_4 PF05119.7 EDO03060.1 - 0.048 13.8 0.0 0.092 12.9 0.0 1.5 1 1 0 1 1 1 0 Phage terminase, small subunit DUF2642 PF10842.3 EDO03060.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) DUF3237 PF11578.3 EDO03062.1 - 2.8e-22 78.6 0.0 3.3e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) QRPTase_C PF01729.14 EDO03063.1 - 3.3e-54 182.9 0.1 4.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EDO03063.1 - 9.6e-23 79.8 0.0 2.8e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PHB_depo_C PF06850.6 EDO03063.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 PHB de-polymerase C-terminus PRAI PF00697.17 EDO03063.1 - 0.031 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase F-box PF00646.28 EDO03064.1 - 6.9e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain RVT_1 PF00078.22 EDO03066.1 - 2.1e-34 118.7 0.0 4.9e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDO03066.1 - 2.8e-13 49.5 0.0 9.2e-13 47.8 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.1 EDO03067.1 - 0.025 14.2 0.3 0.086 12.5 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle Sulfotransfer_2 PF03567.9 EDO03069.1 - 0.044 13.4 0.0 0.048 13.3 0.0 1.3 1 1 0 1 1 1 0 Sulfotransferase family GST_N_2 PF13409.1 EDO03075.1 - 2.5e-18 65.8 0.0 5.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO03075.1 - 2.7e-12 46.4 0.0 5.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO03075.1 - 2.7e-06 27.7 0.0 4.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDO03075.1 - 4.7e-05 23.5 0.0 0.069 13.3 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO03075.1 - 0.0001 22.2 0.0 0.00027 20.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.22 EDO03076.1 - 4.7e-50 169.4 0.0 9.7e-30 103.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO03076.1 - 1.6e-34 119.5 41.8 2.8e-22 79.4 10.4 3.7 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EDO03076.1 - 3.5e-10 39.5 6.1 0.00047 19.4 0.1 4.5 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO03076.1 - 3.2e-08 33.8 1.5 0.0026 17.7 0.0 4.3 2 2 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EDO03076.1 - 6e-07 29.9 0.2 0.00013 22.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO03076.1 - 1e-06 27.8 0.1 0.0049 15.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EDO03076.1 - 1.5e-06 28.3 0.3 0.018 15.0 0.3 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDO03076.1 - 4e-06 26.2 0.3 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO03076.1 - 7e-05 22.9 0.5 3 7.9 0.2 3.5 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDO03076.1 - 0.00021 20.5 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDO03076.1 - 0.00034 20.0 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDO03076.1 - 0.00045 19.7 0.0 0.96 8.8 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 EDO03076.1 - 0.00049 20.0 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EDO03076.1 - 0.0016 19.2 0.0 0.63 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO03076.1 - 0.0038 16.3 0.1 3 6.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ArgK PF03308.11 EDO03076.1 - 0.0042 15.8 0.2 0.04 12.7 0.1 2.3 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EDO03076.1 - 0.012 15.1 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EDO03076.1 - 0.027 14.0 0.1 15 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EDO03076.1 - 0.029 14.8 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EDO03076.1 - 0.03 14.0 0.2 1.4 8.6 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 EDO03076.1 - 0.034 13.9 3.1 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF1256 PF06866.6 EDO03076.1 - 0.036 13.2 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) NB-ARC PF00931.17 EDO03076.1 - 0.037 12.8 0.0 2.3 6.9 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain IstB_IS21 PF01695.12 EDO03076.1 - 0.072 12.4 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EDO03076.1 - 0.082 13.2 0.1 11 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDO03076.1 - 0.085 12.5 2.4 6.1 6.4 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA PF00004.24 EDO03076.1 - 0.092 12.9 0.1 9 6.4 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EDO03076.1 - 0.11 11.4 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EDO03076.1 - 0.12 12.2 0.0 19 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EDO03076.1 - 0.13 11.7 0.0 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase Adeno_IVa2 PF02456.10 EDO03076.1 - 0.14 10.8 0.0 0.3 9.6 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein MFS_1 PF07690.11 EDO03077.1 - 4.7e-40 137.3 61.8 2.3e-39 135.1 41.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO03077.1 - 9.8e-15 54.0 10.5 9.8e-15 54.0 7.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EDO03077.1 - 1.2 9.0 8.5 2 8.2 0.2 3.1 3 0 0 3 3 3 0 MFS_1 like family Gly_transf_sug PF04488.10 EDO03078.1 - 1e-11 45.1 0.2 2.3e-11 44.0 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.17 EDO03079.1 - 3.2e-33 114.9 33.2 4.1e-33 114.6 23.0 1.1 1 0 0 1 1 1 1 Acyltransferase family PocR PF10114.4 EDO03081.1 - 0.2 10.8 1.7 0.23 10.6 1.2 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR A2L_zn_ribbon PF08792.5 EDO03081.1 - 3.6 7.1 11.0 0.53 9.7 0.6 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain MFS_1 PF07690.11 EDO03093.1 - 7.2e-37 126.9 48.6 1.3e-32 112.9 13.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO03093.1 - 1.6e-12 46.7 6.2 6.1e-11 41.5 0.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EDO03093.1 - 2.5e-11 42.6 0.0 1.9e-05 23.2 0.0 3.6 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EDO03093.1 - 0.00093 18.9 2.7 0.007 16.1 0.1 2.9 3 0 0 3 3 3 1 MFS_1 like family Acetyltransf_1 PF00583.19 EDO03095.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDO03095.1 - 9e-05 22.5 0.0 0.00021 21.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDO03095.1 - 0.00078 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO03095.1 - 0.08 12.7 0.0 1.8 8.4 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO03095.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Glyco_tranf_2_4 PF13704.1 EDO03097.1 - 3.7e-10 39.9 0.3 7.2e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EDO03097.1 - 4.1e-06 26.2 2.6 7.2e-06 25.5 1.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Ctr PF04145.10 EDO03099.1 - 6.8e-32 110.5 1.0 8.1e-32 110.2 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Zn_clus PF00172.13 EDO03100.1 - 8.8e-07 28.7 11.2 1.5e-06 28.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF842 PF05811.8 EDO03100.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF4290 PF14123.1 EDO03101.1 - 0.051 12.7 0.1 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) adh_short PF00106.20 EDO03102.1 - 6.8e-15 55.3 0.9 9.4e-15 54.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO03102.1 - 5.7e-06 26.1 0.2 9.2e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDO03102.1 - 0.0004 20.1 0.2 0.00078 19.1 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EDO03102.1 - 0.0044 15.9 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Zip PF02535.17 EDO03103.1 - 9.2e-52 176.0 1.8 1.1e-51 175.8 1.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Malate_synthase PF01274.17 EDO03104.1 - 1.2e-228 759.4 0.0 1.3e-228 759.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Collagen PF01391.13 EDO03106.1 - 2.2e-07 30.3 14.9 3e-07 29.8 10.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Nop14 PF04147.7 EDO03106.1 - 8.7 4.1 13.0 8 4.2 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family Tetraspannin PF00335.15 EDO03107.1 - 1.2e-06 27.9 11.8 1.6e-06 27.5 8.2 1.1 1 0 0 1 1 1 1 Tetraspanin family SRF-TF PF00319.13 EDO03109.1 - 2.9e-23 80.8 0.4 3.9e-23 80.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 EDO03109.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) vATP-synt_E PF01991.13 EDO03110.1 - 1.3e-60 204.1 11.3 1.5e-60 203.8 7.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit BCDHK_Adom3 PF10436.4 EDO03111.1 - 0.023 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PepSY_TM_3 PF13706.1 EDO03113.1 - 0.045 13.1 1.7 0.087 12.2 1.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix CoxIIa PF08113.6 EDO03113.1 - 1.5 8.6 4.1 2.9 7.6 2.8 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Sdh_cyt PF01127.17 EDO03113.1 - 2.1 8.1 5.3 3.1 7.6 3.7 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SEN1_N PF12726.2 EDO03114.1 - 1.7e-205 684.3 8.9 2.2e-205 683.9 6.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EDO03114.1 - 4e-67 226.2 0.9 4e-67 226.2 0.7 2.7 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDO03114.1 - 1.2e-61 207.5 0.0 2.7e-61 206.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO03114.1 - 7e-11 41.7 0.1 2.4e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDO03114.1 - 6e-08 32.4 0.3 7.8e-05 22.3 0.4 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EDO03114.1 - 6.8e-05 22.4 0.0 0.2 11.1 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EDO03114.1 - 0.02 14.3 0.1 0.02 14.3 0.1 2.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase Apc5 PF12862.2 EDO03114.1 - 0.021 14.6 1.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 AAA_25 PF13481.1 EDO03114.1 - 0.024 14.0 0.0 0.64 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EDO03114.1 - 0.41 10.4 6.1 2.7 7.7 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EDO03114.1 - 3.2 8.0 15.7 0.48 10.7 3.5 3.0 2 1 0 2 2 2 0 AAA domain HAP PF03866.8 EDO03118.1 - 1.2 8.8 6.4 1.4 8.7 4.4 1.1 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) DUF2763 PF10961.3 EDO03118.1 - 1.4 9.3 4.3 8.4 6.8 3.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2763) ERCC4 PF02732.10 EDO03119.1 - 8.6e-26 90.4 0.1 2.1e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 ERCC4 domain WH1 PF00568.18 EDO03121.1 - 2.1e-29 101.4 0.3 2.9e-29 101.0 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EDO03121.1 - 0.002 17.6 0.3 0.0047 16.4 0.2 1.7 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.14 EDO03122.1 - 3.6e-28 96.7 0.1 5.1e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 EDO03124.1 - 8e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDO03124.1 - 1e-08 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EDO03124.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EDO03124.1 - 0.0023 17.6 0.0 0.0076 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) TRP PF06011.7 EDO03127.1 - 1.8e-117 392.6 21.9 3.1e-117 391.8 15.2 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDO03127.1 - 9.5e-31 106.7 0.1 1.6e-30 106.0 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Rad21_Rec8_N PF04825.8 EDO03127.1 - 1.1e-25 89.7 0.1 2.2e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDO03127.1 - 0.0078 15.3 0.0 0.022 13.9 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ECH PF00378.15 EDO03130.1 - 1.4e-22 80.0 0.0 1.9e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SRX PF09201.5 EDO03130.1 - 0.058 13.0 1.0 0.1 12.2 0.7 1.3 1 0 0 1 1 1 0 SRX Exo_endo_phos_2 PF14529.1 EDO03131.1 - 2e-15 56.4 0.1 3.4e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDO03131.1 - 8.2e-07 29.2 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EDO03132.1 - 3.9e-27 95.0 0.0 6.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO03132.1 - 3.5e-10 40.3 0.0 6.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Abhydrolase_6 PF12697.2 EDO03133.1 - 7.6e-11 42.3 0.8 1.2e-10 41.7 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO03133.1 - 1.6e-09 37.6 0.1 3e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EDO03133.1 - 2.2e-06 27.1 0.4 0.00019 20.7 0.3 2.1 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 EDO03133.1 - 2.5e-06 26.8 0.3 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EDO03133.1 - 0.0018 17.7 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EDO03133.1 - 0.015 14.5 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DAO PF01266.19 EDO03134.1 - 2.4e-33 115.5 0.3 6.1e-33 114.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 EDO03134.1 - 0.0036 15.9 0.5 0.062 11.8 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 EDO03134.1 - 0.0044 17.1 0.0 5.3 7.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO03134.1 - 0.016 15.0 0.2 0.84 9.3 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDO03134.1 - 0.027 14.4 0.2 0.088 12.8 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO03134.1 - 0.044 12.7 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EDO03134.1 - 0.052 12.6 0.3 0.097 11.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DDE_1 PF03184.14 EDO03136.1 - 1.2e-22 80.1 0.1 1.2e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03136.1 - 2.9e-12 46.1 1.2 1.9e-11 43.5 0.0 2.6 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain SspH PF08141.7 EDO03136.1 - 0.037 14.0 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DivIC PF04977.10 EDO03137.1 - 0.0095 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator Gp-FAR-1 PF05823.7 EDO03137.1 - 0.02 14.8 1.0 0.03 14.2 0.7 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Strep_SA_rep PF06696.6 EDO03137.1 - 0.05 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat bZIP_1 PF00170.16 EDO03137.1 - 0.082 12.8 3.8 0.13 12.2 2.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor DUF1768 PF08719.6 EDO03139.1 - 1.7e-30 105.8 0.1 2.1e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) BAAT_C PF08840.6 EDO03139.1 - 0.099 12.3 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phospholamban PF04272.9 EDO03139.1 - 0.1 12.0 0.8 0.24 10.8 0.6 1.5 1 0 0 1 1 1 0 Phospholamban rve PF00665.21 EDO03141.1 - 2.9e-08 33.8 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO03141.1 - 8.7e-05 22.0 0.3 0.00026 20.5 0.2 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDO03141.1 - 0.032 13.9 0.2 0.077 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DUF3575 PF12099.3 EDO03142.1 - 0.042 12.9 0.2 0.53 9.3 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3575) Sipho_tail PF05709.6 EDO03142.1 - 0.11 11.5 0.2 0.14 11.2 0.1 1.2 1 1 0 1 1 1 0 Phage tail protein WD40 PF00400.27 EDO03144.1 - 3.6e-15 55.1 0.3 2.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EDO03144.1 - 0.018 13.2 0.1 0.02 13.0 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HET PF06985.6 EDO03145.1 - 1.3e-23 83.6 8.2 6.8e-22 78.1 5.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EDO03145.1 - 7.3e-12 44.7 0.0 1.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arabinose_bd PF12625.2 EDO03145.1 - 2.4e-10 40.5 12.6 7.5 6.3 0.0 9.2 3 1 7 10 10 10 3 Arabinose-binding domain of AraC transcription regulator, N-term AAA_16 PF13191.1 EDO03145.1 - 7.2e-08 32.6 0.0 2.8e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO03145.1 - 1.5e-07 31.6 0.0 4.8e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO03145.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EDO03145.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EDO03145.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.7 EDO03145.1 - 0.32 10.2 0.0 0.58 9.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein KaiC PF06745.8 EDO03147.1 - 0.044 12.9 0.3 0.068 12.2 0.2 1.2 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 EDO03149.1 - 2.8e-46 157.1 0.0 6.3e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO03149.1 - 3.2e-28 97.3 0.1 7e-28 96.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO03149.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDO03149.1 - 0.034 13.2 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EDO03149.1 - 0.081 11.3 0.0 0.17 10.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Proteasome PF00227.21 EDO03150.1 - 2e-37 128.3 0.0 2.3e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EDO03151.1 - 3.8e-28 96.3 7.7 9.1e-08 31.7 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EDO03151.1 - 0.043 11.9 0.9 1.5 6.8 0.0 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO03151.1 - 0.065 11.9 0.1 1.2 7.7 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like UCH PF00443.24 EDO03152.1 - 3.2e-26 92.0 0.0 4.8e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO03152.1 - 0.00047 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO03152.1 - 0.0027 17.7 0.4 0.0062 16.6 0.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein FPN1 PF06963.7 EDO03154.1 - 0.022 13.1 0.2 0.05 11.9 0.2 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF869 PF05911.6 EDO03154.1 - 0.63 8.2 53.1 3.8 5.6 22.2 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) RFX5_DNA_bdg PF14621.1 EDO03156.1 - 0.038 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain adh_short PF00106.20 EDO03157.1 - 3.9e-20 72.4 0.1 1.2e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO03157.1 - 1e-16 61.4 0.1 3.4e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M20 PF01546.23 EDO03157.1 - 5.7e-05 22.7 0.0 0.073 12.5 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO03157.1 - 8e-05 22.3 0.0 0.0002 21.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain KR PF08659.5 EDO03157.1 - 0.0032 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 KR domain BDHCT PF08072.6 EDO03157.1 - 0.088 12.9 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 BDHCT (NUC031) domain zf-LITAF-like PF10601.4 EDO03159.1 - 4.2e-27 93.8 6.7 6e-27 93.3 4.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.1 EDO03159.1 - 0.024 14.9 0.2 0.88 9.9 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain CENP-T PF15511.1 EDO03159.1 - 0.19 10.9 6.9 0.23 10.6 4.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Zn_Tnp_IS1595 PF12760.2 EDO03159.1 - 0.39 10.5 2.2 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EDO03159.1 - 0.68 10.2 4.2 2.6 8.4 2.9 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Pro-rich PF15240.1 EDO03159.1 - 1.5 8.9 30.7 2.2 8.3 21.3 1.3 1 0 0 1 1 1 0 Proline-rich TFIIB PF00382.14 EDO03160.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Glyco_hydro_47 PF01532.15 EDO03161.1 - 2.1e-127 425.5 0.0 2.6e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 EDO03161.1 - 0.00086 18.9 0.0 0.0048 16.5 0.0 2.2 3 0 0 3 3 3 1 PA domain Bromodomain PF00439.20 EDO03162.1 - 3.4e-32 110.2 0.1 9.1e-15 54.3 0.1 2.6 2 0 0 2 2 2 2 Bromodomain CKS PF01111.14 EDO03163.1 - 8.6e-36 121.5 0.9 1.3e-35 121.0 0.6 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EDO03163.1 - 0.017 15.0 3.0 0.35 10.9 0.1 2.7 2 0 0 2 2 2 0 APC 15 residue motif ERO1 PF04137.10 EDO03164.1 - 1e-137 458.9 0.0 1.3e-137 458.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ATP_Ca_trans_C PF12424.3 EDO03164.1 - 0.037 14.3 0.5 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal HSP70 PF00012.15 EDO03165.1 - 8e-230 763.8 8.7 9e-230 763.6 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO03165.1 - 2.3e-15 56.0 0.1 2e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDO03165.1 - 0.00075 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RRF PF01765.14 EDO03167.1 - 2e-38 131.4 0.0 2e-38 131.4 0.0 1.4 2 0 0 2 2 2 1 Ribosome recycling factor SR-25 PF10500.4 EDO03167.1 - 0.014 14.9 6.9 0.014 14.9 4.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein APG17 PF04108.7 EDO03167.1 - 3.7 6.2 6.4 0.74 8.5 1.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 FoP_duplication PF13865.1 EDO03168.1 - 0.31 11.5 0.2 0.31 11.5 0.1 2.3 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 APC_CDC26 PF10471.4 EDO03169.1 - 1.3e-17 64.2 3.3 1.3e-17 64.2 2.3 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 Miff PF05644.6 EDO03169.1 - 1.6 8.3 7.1 5.3 6.6 5.0 1.8 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff YqfQ PF14181.1 EDO03169.1 - 2.2 8.2 5.7 3.9 7.4 0.3 2.1 2 0 0 2 2 2 0 YqfQ-like protein DDHD PF02862.12 EDO03169.1 - 3.9 7.2 5.4 5.7 6.6 3.8 1.2 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 EDO03169.1 - 4 6.7 19.2 2.1 7.6 5.7 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_M1 PF01433.15 EDO03170.1 - 8.3e-06 25.1 0.2 0.16 11.0 0.1 3.5 3 1 0 3 3 3 2 Peptidase family M1 HEAT_2 PF13646.1 EDO03170.1 - 0.0044 17.2 0.0 0.058 13.6 0.0 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EDO03170.1 - 0.14 12.3 0.0 15 6.0 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat SAS4 PF15460.1 EDO03171.1 - 5.4e-32 109.6 1.4 5.4e-32 109.6 1.0 2.8 3 1 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Z1 PF10593.4 EDO03171.1 - 0.14 11.3 1.0 0.35 10.0 0.7 1.6 1 0 0 1 1 1 0 Z1 domain DUF2072 PF09845.4 EDO03171.1 - 4.2 7.2 6.3 0.67 9.8 0.3 2.5 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DDE_1 PF03184.14 EDO03173.1 - 7.4e-13 48.1 0.0 1.1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03173.1 - 2.2e-09 36.9 0.8 5.6e-09 35.6 0.0 2.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain E1-E2_ATPase PF00122.15 EDO03175.1 - 3.3e-54 183.3 0.0 7.4e-54 182.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO03175.1 - 1.5e-47 162.7 1.3 1.5e-47 162.7 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EDO03175.1 - 1.6e-45 153.0 0.1 1.2e-11 44.6 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EDO03175.1 - 1.8e-14 54.3 0.0 4.8e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO03175.1 - 2.5e-06 27.2 1.1 0.00027 20.5 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FAM70 PF14967.1 EDO03175.1 - 0.01 15.0 0.3 7.7 5.6 0.0 3.4 3 1 1 4 4 4 0 FAM70 protein DUF2089 PF09862.4 EDO03175.1 - 0.28 10.9 2.2 19 5.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2089) DUF3112 PF11309.3 EDO03176.1 - 8.3e-39 132.9 8.8 1.1e-38 132.5 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF155 PF02582.9 EDO03177.1 - 4.1e-61 205.9 0.2 6.4e-61 205.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aegerolysin PF06355.8 EDO03178.1 - 0.077 12.8 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Aegerolysin UBA PF00627.26 EDO03179.1 - 1.8e-08 33.9 1.9 6.8e-08 32.1 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain UPF0154 PF03672.8 EDO03179.1 - 0.29 10.7 4.1 0.3 10.7 0.0 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) ADH_zinc_N PF00107.21 EDO03180.1 - 2.5e-35 120.8 0.1 4.1e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO03180.1 - 1.8e-12 48.2 0.0 3.8e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO03180.1 - 5.4e-07 29.3 0.0 2.4e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EDO03180.1 - 0.0064 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EDO03180.1 - 0.029 13.9 0.8 0.4 10.2 0.3 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_8 PF08022.7 EDO03181.1 - 1.3e-22 79.6 0.0 2.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDO03181.1 - 1.6e-17 63.8 0.0 3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDO03181.1 - 3.1e-17 62.8 8.1 6.7e-17 61.7 5.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EDO03181.1 - 3.5e-05 23.8 0.0 9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF457 PF04307.9 EDO03181.1 - 0.68 9.2 6.5 1.5 8.1 4.5 1.6 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Myosin_head PF00063.16 EDO03182.1 - 2.9e-231 769.2 5.4 4.5e-231 768.6 3.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EDO03182.1 - 1.6e-41 141.8 0.0 4.1e-41 140.5 0.0 1.8 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EDO03182.1 - 2.9e-11 42.5 0.1 6.1e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO03182.1 - 9.4e-09 34.7 0.1 2.8e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO03182.1 - 1.3e-08 34.1 0.0 3.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EDO03182.1 - 0.0052 16.9 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Hpr_kinase_C PF07475.7 EDO03182.1 - 0.0087 15.3 0.3 3.8 6.7 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain IQ PF00612.22 EDO03182.1 - 0.013 15.0 4.0 3.8 7.4 0.0 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EDO03182.1 - 0.022 13.8 0.3 0.059 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EDO03182.1 - 0.049 14.4 0.0 0.19 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EDO03182.1 - 0.084 12.5 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SH3_3 PF08239.6 EDO03182.1 - 0.085 13.0 2.9 0.057 13.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain AAA_19 PF13245.1 EDO03182.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF1713 PF08213.6 EDO03183.1 - 6.4e-14 51.2 19.4 6.4e-14 51.2 13.5 2.2 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EDO03183.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet20 MFS_1 PF07690.11 EDO03186.1 - 6.7e-34 117.1 61.0 3.8e-32 111.3 38.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO03186.1 - 6.6e-12 44.4 13.3 6.6e-12 44.4 9.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-DHHC PF01529.15 EDO03187.1 - 3.8e-36 124.1 4.6 6.2e-36 123.4 3.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Mo-co_dimer PF03404.11 EDO03187.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Transglut_core3 PF13471.1 EDO03187.1 - 0.032 14.0 0.7 0.061 13.1 0.5 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_hydro_71 PF03659.9 EDO03189.1 - 1.4e-27 96.1 2.9 5.3e-11 41.6 0.1 3.3 2 1 1 3 3 3 3 Glycosyl hydrolase family 71 Peptidase_S8 PF00082.17 EDO03189.1 - 1e-08 34.7 5.4 0.00015 21.0 0.0 3.5 1 1 2 3 3 3 2 Subtilase family UDPGP PF01704.13 EDO03191.1 - 7e-55 186.2 0.0 9.5e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EDO03191.1 - 0.04 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 EDO03191.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster UDG PF03167.14 EDO03192.1 - 7.5e-23 80.6 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ADH_zinc_N PF00107.21 EDO03193.1 - 2.1e-16 59.6 0.0 3.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO03193.1 - 7.2e-14 52.7 0.0 1.3e-13 51.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EDO03193.1 - 5.8e-05 22.9 0.1 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF2855 PF11017.3 EDO03193.1 - 0.00057 19.1 0.0 0.001 18.3 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.19 EDO03193.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 EDO03194.1 - 3.2e-20 72.0 0.3 8e-20 70.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EDO03194.1 - 0.0034 17.2 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EDO03196.1 - 8.5e-22 77.8 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO03196.1 - 4.9e-09 36.0 0.0 6.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDO03196.1 - 2.6e-05 23.7 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDO03196.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDO03196.1 - 0.00019 21.4 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EDO03196.1 - 0.00071 18.8 1.2 0.001 18.2 0.9 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EDO03196.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EDO03196.1 - 0.042 13.9 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 EDO03197.1 - 2.1e-52 178.1 0.0 2.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDO03197.1 - 1.4e-10 40.6 0.0 0.00023 20.1 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain GMC_oxred_C PF05199.8 EDO03197.1 - 2.3e-09 37.6 0.0 4.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDO03197.1 - 9.3e-07 28.0 0.0 4.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO03197.1 - 0.00011 22.1 0.4 0.00025 21.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDO03197.1 - 0.00024 20.1 0.1 0.00035 19.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EDO03197.1 - 0.00056 19.8 0.4 0.0011 18.8 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDO03197.1 - 0.0019 16.8 0.1 0.0028 16.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EDO03197.1 - 0.0049 16.9 0.8 3.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO03197.1 - 0.0058 15.1 0.3 0.0091 14.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EDO03197.1 - 0.0099 15.0 0.2 0.044 12.8 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EDO03197.1 - 0.083 12.6 0.6 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_2 PF00891.13 EDO03198.1 - 1.9e-30 105.8 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EDO03198.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03198.1 - 0.023 15.2 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03198.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EDO03198.1 - 0.098 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_4 PF01565.18 EDO03199.1 - 2.2e-20 72.5 4.7 4.7e-20 71.4 3.3 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EDO03199.1 - 3.2e-12 46.1 3.2 8e-05 21.8 1.4 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDO03199.1 - 9.7e-05 21.4 0.2 0.0026 16.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO03199.1 - 0.00021 21.2 0.2 0.00051 20.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO03199.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO03199.1 - 0.021 13.6 0.2 0.034 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDO03199.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO03200.1 - 1.3e-25 90.6 0.2 1.7e-23 83.7 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO03200.1 - 6.7e-19 67.4 2.8 5.5e-17 61.1 0.0 3.2 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDO03200.1 - 3.4e-10 39.3 0.2 5.9e-08 32.0 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDO03200.1 - 3.6e-07 30.2 0.0 2.2e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO03200.1 - 2.4e-06 27.4 0.0 6.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO03200.1 - 9.1e-05 21.5 0.3 0.00071 18.5 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO03200.1 - 0.0031 17.8 0.4 2.8 8.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO03200.1 - 0.0043 16.8 3.9 0.03 14.0 0.0 3.6 4 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EDO03200.1 - 0.04 12.7 0.1 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain ABM PF03992.11 EDO03200.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Thi4 PF01946.12 EDO03200.1 - 0.055 12.5 0.5 0.3 10.1 0.1 2.2 3 0 0 3 3 3 0 Thi4 family ketoacyl-synt PF00109.21 EDO03201.1 - 1.5e-80 270.3 0.0 3.4e-80 269.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDO03201.1 - 4.3e-34 118.2 0.0 9.3e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EDO03201.1 - 2.3e-30 104.8 0.2 6e-30 103.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EDO03201.1 - 1.5e-26 94.0 0.0 1.5e-24 87.4 0.0 2.5 1 1 1 2 2 2 1 Thioesterase domain PS-DH PF14765.1 EDO03201.1 - 2.9e-17 62.7 0.0 5.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 EDO03201.1 - 1e-10 41.5 0.0 0.00094 18.9 0.0 3.6 4 0 0 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO03201.1 - 1.7e-08 34.6 0.1 8.4e-05 22.5 0.0 3.2 2 1 0 2 2 2 2 Alpha/beta hydrolase family PP-binding PF00550.20 EDO03201.1 - 2.9e-06 27.4 0.9 7.9e-06 26.0 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EDO03201.1 - 4e-05 22.7 0.0 8.4e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EDO03201.1 - 0.011 15.0 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) IBN_N PF03810.14 EDO03202.1 - 9.4e-11 41.4 0.6 1.5e-09 37.5 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EDO03202.1 - 0.00083 19.2 0.7 0.00083 19.2 0.5 4.2 4 1 1 5 5 5 1 Exportin 1-like protein DUF2063 PF09836.4 EDO03202.1 - 0.055 13.4 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Chromo PF00385.19 EDO03203.1 - 3.6e-14 52.1 1.1 5.6e-14 51.5 0.7 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EDO03204.1 - 1.3e-05 24.6 0.1 1.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDO03205.1 - 0.029 14.2 1.7 0.051 13.5 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EDO03205.1 - 0.52 9.8 3.8 1.2 8.7 2.7 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pribosyltran PF00156.22 EDO03207.1 - 3.8e-17 62.1 0.0 6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO03207.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EDO03207.1 - 0.03 13.2 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like MFS_1_like PF12832.2 EDO03208.1 - 2.7e-08 33.4 0.9 5e-07 29.4 0.1 4.0 4 0 0 4 4 4 2 MFS_1 like family Catalase PF00199.14 EDO03209.1 - 3.7e-167 555.8 0.2 4.8e-167 555.4 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDO03209.1 - 6.8e-17 61.0 0.0 2.1e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive YscO PF07321.7 EDO03209.1 - 0.0017 18.2 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO DNA_pol_A_exo1 PF01612.15 EDO03210.1 - 4.6e-15 55.5 0.0 7.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 EDO03211.1 - 4.2e-19 67.8 0.1 4.7e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain DUF1923 PF09083.5 EDO03212.1 - 0.51 9.8 2.5 8 6.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) HATPase_c PF02518.21 EDO03215.1 - 3.6e-22 78.1 0.1 7.1e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDO03215.1 - 1.3e-20 73.5 0.0 3.9e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 EDO03215.1 - 1.9e-20 72.7 3.5 7e-12 45.2 1.4 3.6 3 0 0 3 3 3 3 PAS fold HisKA PF00512.20 EDO03215.1 - 2.1e-20 72.4 0.0 6.5e-20 70.8 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EDO03215.1 - 4.3e-14 52.7 0.1 2.2e-07 31.2 0.0 3.9 3 1 0 3 3 3 2 PAS domain PAS PF00989.19 EDO03215.1 - 1.9e-10 40.5 0.0 8.7e-05 22.2 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EDO03215.1 - 3.3e-10 39.9 0.2 2.6e-07 30.6 0.1 3.0 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EDO03215.1 - 0.047 13.5 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 PAS domain UPF0565 PF10561.4 EDO03215.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Peptidase_M13_N PF05649.8 EDO03217.1 - 7.4e-96 321.5 0.0 1e-95 321.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EDO03217.1 - 3.7e-56 189.5 0.1 1.7e-55 187.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M13 SRI PF08236.6 EDO03217.1 - 0.0077 16.1 0.3 0.032 14.1 0.1 2.1 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Herpes_UL45 PF05473.7 EDO03217.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein Cytochrom_B561 PF03188.11 EDO03218.1 - 5e-17 62.0 7.1 1e-16 61.0 4.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 UPF0233 PF06781.7 EDO03218.1 - 0.027 14.1 0.0 0.027 14.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF4079 PF13301.1 EDO03218.1 - 7.4 6.5 19.6 0.11 12.5 3.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Allantoicase PF03561.10 EDO03219.1 - 9.2e-106 349.8 0.1 5.6e-57 191.4 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 EDO03220.1 - 2.5e-18 65.8 3.6 3.6e-16 58.9 2.5 2.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EDO03220.1 - 9.2e-15 54.7 0.3 3e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO03220.1 - 7.2e-13 47.6 0.0 1.9e-05 24.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EDO03220.1 - 1.2e-09 38.1 0.0 4.9e-07 29.8 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO03220.1 - 2.9e-07 30.8 0.7 1e-05 25.9 0.0 3.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO03220.1 - 4.1e-06 26.5 0.0 0.11 12.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Mnd1 PF03962.10 EDO03220.1 - 2.7 7.5 6.1 13 5.4 0.0 3.2 3 0 0 3 3 3 0 Mnd1 family RabGAP-TBC PF00566.13 EDO03221.1 - 4.4e-36 124.3 0.0 7e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain gag-asp_proteas PF13975.1 EDO03222.1 - 6.3e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO03222.1 - 2.7e-07 30.9 0.0 1.6e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 EDO03222.1 - 0.0011 18.8 2.3 0.002 17.9 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.5 EDO03222.1 - 0.0037 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDO03222.1 - 0.062 13.3 1.9 0.2 11.7 0.8 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EDO03222.1 - 0.12 12.1 1.3 0.24 11.1 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.15 EDO03222.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease GAGA PF09237.6 EDO03224.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 GAGA factor DUF2722 PF10846.3 EDO03226.1 - 4.5e-06 25.9 0.5 5.8e-06 25.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Beta-lactamase PF00144.19 EDO03231.1 - 5.8e-42 143.8 0.0 8.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Lipoprotein_19 PF13617.1 EDO03231.1 - 0.033 13.8 0.1 0.078 12.6 0.1 1.6 1 0 0 1 1 1 0 YnbE-like lipoprotein HATPase_c PF02518.21 EDO03232.1 - 2.3e-28 98.1 0.0 6.9e-28 96.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDO03232.1 - 2.2e-19 69.2 0.3 8.6e-19 67.3 0.2 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EDO03232.1 - 5.8e-16 58.4 0.3 3.1e-15 56.1 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain GAF_2 PF13185.1 EDO03232.1 - 1.1e-10 42.2 0.1 3.4e-10 40.5 0.0 2.0 2 0 0 2 2 1 1 GAF domain Pkinase PF00069.20 EDO03232.1 - 2.2e-07 30.2 0.0 5.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EDO03232.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EDO03232.1 - 1.5e-06 28.3 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EDO03232.1 - 0.0064 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 EDO03232.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 EDO03232.1 - 0.019 14.9 5.2 2 8.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDO03232.1 - 0.053 13.1 1.0 7.2 6.3 0.2 3.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EDO03232.1 - 0.5 10.4 3.5 12 6.0 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPT PF03151.11 EDO03234.1 - 4.7e-25 88.0 17.2 4.7e-25 88.0 11.9 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EDO03234.1 - 7.2e-05 21.8 27.5 0.0016 17.4 19.1 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EDO03234.1 - 1.7 8.7 44.2 0.26 11.3 11.1 2.8 3 0 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.1 EDO03235.1 - 2e-09 37.3 0.0 4.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDO03235.1 - 1.8e-05 24.9 0.1 6.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDO03235.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EDO03235.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO03235.1 - 0.004 16.9 0.2 0.054 13.2 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EDO03235.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DUF1344 PF07076.6 EDO03235.1 - 0.015 14.8 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) HI0933_like PF03486.9 EDO03235.1 - 0.018 13.5 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EDO03235.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EDO03235.1 - 0.023 13.6 0.4 0.047 12.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 EDO03235.1 - 0.028 13.3 0.0 0.1 11.4 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EDO03235.1 - 0.046 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EDO03235.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 EDO03237.1 - 1.1e-13 50.7 1.1 1.6e-13 50.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.1 EDO03238.1 - 1.1e-11 45.2 0.0 5.9e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO03238.1 - 2.5e-06 28.0 0.0 0.0006 20.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO03238.1 - 3.7e-06 26.5 0.0 6.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like zf-primase PF09329.6 EDO03239.1 - 0.077 12.6 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Primase zinc finger WD40 PF00400.27 EDO03240.1 - 1.2e-42 142.2 2.6 6.3e-07 29.0 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EDO03240.1 - 5.6e-11 41.9 3.6 5.6e-11 41.9 1.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDO03240.1 - 1.1e-08 34.5 2.0 8.3e-08 31.6 0.6 2.4 2 0 0 2 2 2 1 F-box domain BBS2_Mid PF14783.1 EDO03240.1 - 1.1e-05 25.1 0.1 3.7 7.3 0.0 4.4 4 1 1 5 5 5 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EDO03240.1 - 0.0003 19.0 0.3 0.36 8.9 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO03240.1 - 0.15 10.8 0.1 6.8 5.3 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like MgtE_N PF03448.12 EDO03240.1 - 0.17 12.2 0.0 1.4 9.3 0.0 2.0 1 1 1 2 2 2 0 MgtE intracellular N domain PH_10 PF15411.1 EDO03241.1 - 2.4e-43 147.0 0.2 5.3e-43 145.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EDO03241.1 - 1e-32 112.0 0.0 1.9e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EDO03241.1 - 1e-31 110.2 0.2 1.7e-31 109.4 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EDO03241.1 - 2.9e-08 33.2 0.0 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EDO03241.1 - 0.0037 17.4 0.8 0.0098 16.0 0.4 1.9 2 0 0 2 2 2 1 PH domain DUF4632 PF15451.1 EDO03241.1 - 0.039 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) CHCH PF06747.8 EDO03242.1 - 0.0022 17.8 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EDO03242.1 - 0.033 14.3 0.4 0.043 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) GCFC PF07842.7 EDO03244.1 - 6.4e-84 281.5 4.0 6.4e-84 281.5 2.8 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EDO03244.1 - 1.2e-17 63.9 13.5 1.2e-17 63.9 9.4 2.9 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EDO03244.1 - 3.2e-14 52.4 3.7 3.2e-14 52.4 2.6 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EDO03244.1 - 1.2e-06 28.2 1.5 1.2e-06 28.2 1.0 3.3 3 2 1 4 4 4 1 DExH-box splicing factor binding site Nucleoplasmin PF03066.10 EDO03244.1 - 3.6 7.1 17.2 0.36 10.3 4.2 3.2 3 0 0 3 3 3 0 Nucleoplasmin NOA36 PF06524.7 EDO03244.1 - 9.7 5.3 10.0 20 4.2 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein Kelch_4 PF13418.1 EDO03246.1 - 5.6e-26 90.0 7.0 1e-08 34.7 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO03246.1 - 2.5e-24 84.7 1.4 1.2e-07 31.4 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EDO03246.1 - 4.8e-22 77.1 2.8 5.4e-05 23.1 0.0 4.8 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EDO03246.1 - 1.6e-20 72.3 0.2 2.8e-05 23.5 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EDO03246.1 - 5.7e-19 67.7 5.0 2.9e-07 30.4 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EDO03246.1 - 3.3e-18 64.6 3.1 0.00096 18.8 0.0 5.0 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EDO03246.1 - 2.6e-10 40.2 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EDO03246.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 EDO03247.1 - 3.4e-24 83.7 23.0 2.9e-06 26.9 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO03247.1 - 1.8e-07 31.0 0.2 8e-05 22.4 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EDO03247.1 - 0.016 14.8 3.2 0.27 10.9 0.4 3.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term TFIIA PF03153.8 EDO03248.1 - 3.7e-79 267.3 63.9 2.2e-55 189.0 33.1 2.8 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit EURL PF06937.6 EDO03248.1 - 3.9 6.8 16.4 6.5 6.0 11.3 1.3 1 0 0 1 1 1 0 EURL protein Med15 PF09606.5 EDO03248.1 - 7.2 4.6 95.7 11 4.0 66.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1162 PF06650.7 EDO03249.1 - 4.6e-91 304.8 0.0 2.4e-88 295.9 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EDO03249.1 - 3.8e-44 148.9 0.1 1.2e-43 147.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EDO03249.1 - 2.2e-06 27.7 0.1 1.8e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EDO03250.1 - 5.6e-41 139.8 8.7 7.7e-41 139.3 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1469 PF07332.6 EDO03250.1 - 0.011 15.4 0.0 0.048 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) TP2 PF01254.13 EDO03251.1 - 0.12 12.6 4.3 0.15 12.4 3.0 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 Pkinase PF00069.20 EDO03253.1 - 2.5e-15 56.3 0.1 5e-14 52.0 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO03253.1 - 8.9e-07 28.2 0.0 4.6e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO03253.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like His_Phos_1 PF00300.17 EDO03254.1 - 3.8e-29 101.8 0.0 8.6e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EDO03254.1 - 0.0035 16.7 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.7 EDO03255.1 - 1e-39 135.3 13.3 1.5e-39 134.7 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Hex_IIIa PF02455.11 EDO03255.1 - 0.046 12.4 5.7 0.057 12.1 4.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Peptidase_S49_N PF08496.5 EDO03255.1 - 0.1 12.3 2.8 0.14 11.9 1.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.7 EDO03255.1 - 0.43 9.1 4.1 0.46 9.0 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Vfa1 PF08432.5 EDO03255.1 - 0.45 10.5 8.0 0.72 9.8 5.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Med19 PF10278.4 EDO03255.1 - 0.46 10.1 7.1 0.7 9.5 5.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.6 EDO03255.1 - 0.62 9.6 11.0 0.83 9.2 7.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EDO03255.1 - 0.95 8.5 5.1 1 8.4 3.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YqfQ PF14181.1 EDO03255.1 - 3.6 7.6 7.7 1.3 9.0 3.4 1.8 2 0 0 2 2 2 0 YqfQ-like protein CDC45 PF02724.9 EDO03255.1 - 4.6 5.1 8.3 5.2 4.9 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 EDO03255.1 - 5.1 6.9 5.1 5.6 6.8 2.8 1.7 1 1 1 2 2 2 0 Testis-expressed protein 19 Cpn60_TCP1 PF00118.19 EDO03256.1 - 1.2e-160 535.3 0.5 1.4e-160 535.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family APH PF01636.18 EDO03257.1 - 1.3e-13 51.3 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO03257.1 - 8.8e-05 22.1 0.2 0.00021 20.9 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EDO03257.1 - 0.0084 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EDO03257.1 - 0.045 13.0 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 RIO1 family SAB PF04382.8 EDO03257.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 SAB domain DUF1138 PF06592.8 EDO03257.1 - 0.14 12.1 0.1 0.46 10.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) TK PF00265.13 EDO03258.1 - 0.089 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Thymidine kinase MFS_1 PF07690.11 EDO03261.1 - 3.1e-23 82.0 19.2 3.1e-23 82.0 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDO03261.1 - 0.0068 16.1 1.6 0.011 15.5 0.3 2.0 2 0 0 2 2 2 1 MFS_1 like family WD40 PF00400.27 EDO03263.1 - 1.1e-36 123.4 4.3 1.4e-08 34.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EDO03263.1 - 1.9e-31 107.9 17.1 3.2e-31 107.1 11.9 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EDO03263.1 - 7e-07 29.1 0.4 1.9e-05 24.5 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A SUKH_5 PF14567.1 EDO03263.1 - 0.011 15.1 0.0 0.12 11.8 0.0 2.5 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Cytochrom_D1 PF02239.11 EDO03263.1 - 0.038 12.2 0.0 0.11 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PCI PF01399.22 EDO03264.1 - 2.2e-21 76.1 0.1 7.2e-21 74.4 0.1 1.9 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.4 EDO03264.1 - 0.00057 19.3 0.3 0.0013 18.1 0.2 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.1 EDO03264.1 - 0.0026 17.4 0.7 4.2 7.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat GFA PF04828.9 EDO03267.1 - 1.4e-18 66.5 0.1 2.3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2945 PF11160.3 EDO03268.1 - 0.0085 15.8 0.6 0.01 15.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) T4_gp9_10 PF07880.6 EDO03269.1 - 0.037 13.0 0.0 0.037 13.0 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Trp_leader2 PF08056.6 EDO03270.1 - 0.0055 16.6 1.0 0.0087 16.0 0.7 1.3 1 0 0 1 1 1 1 Tryptophan operon leader peptide EF-hand_1 PF00036.27 EDO03270.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 EF hand PI-PLC-X PF00388.14 EDO03273.1 - 2.5e-59 198.8 0.0 5.7e-59 197.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDO03273.1 - 2.2e-39 134.1 0.3 9e-39 132.1 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EDO03273.1 - 1.9e-08 34.0 0.0 8.9e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 C2 domain GDPD PF03009.12 EDO03273.1 - 0.00026 20.5 0.0 0.00065 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_like PF09279.6 EDO03273.1 - 0.0015 18.5 0.5 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 EDO03273.1 - 0.025 14.2 0.5 0.052 13.2 0.4 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EDO03273.1 - 0.06 12.6 2.8 0.13 11.6 0.1 2.8 3 0 0 3 3 3 0 EF hand Pox_F16 PF04708.7 EDO03273.1 - 0.067 12.4 0.2 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein EF-hand_7 PF13499.1 EDO03273.1 - 0.15 12.2 1.4 0.59 10.3 0.4 2.3 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.1 EDO03273.1 - 0.62 10.1 3.2 0.85 9.6 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain Fungal_trans_2 PF11951.3 EDO03274.1 - 1.6e-10 40.1 2.4 3.1e-08 32.6 0.4 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO03274.1 - 0.0008 19.2 9.1 0.0014 18.5 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDO03275.1 - 1.4e-27 96.3 67.6 4.9e-27 94.5 42.1 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.16 EDO03276.1 - 4.8e-132 440.6 44.7 6e-132 440.3 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO03276.1 - 2.4e-34 118.6 46.4 3.2e-34 118.2 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1771 PF08590.5 EDO03278.1 - 9.6e-24 83.1 10.0 9.6e-24 83.1 6.9 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EDO03278.1 - 2.6e-16 59.5 0.3 6.9e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 Smr domain Fungal_trans PF04082.13 EDO03279.1 - 2.2e-10 39.8 0.1 5.2e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO03279.1 - 3.6e-06 26.7 9.8 3.6e-06 26.7 6.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYTT PF07078.6 EDO03279.1 - 0.024 13.9 0.4 0.056 12.7 0.1 1.7 2 0 0 2 2 2 0 Forty-two-three protein Myb_DNA-bind_6 PF13921.1 EDO03284.1 - 5.2e-06 26.4 1.1 0.05 13.7 0.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDO03284.1 - 0.0033 17.5 4.7 0.015 15.4 2.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EDO03284.1 - 0.014 15.9 2.7 0.073 13.7 0.1 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EDO03284.1 - 0.22 11.4 2.6 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO03284.1 - 0.51 10.4 3.5 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain PDGF_N PF04692.8 EDO03284.1 - 7.2 7.1 10.2 22 5.6 0.2 2.7 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Methyltransf_4 PF02390.12 EDO03285.1 - 0.035 13.1 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Herpes_US12 PF05363.7 EDO03286.1 - 0.12 12.8 0.1 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus US12 family tRNA-synt_1e PF01406.14 EDO03287.1 - 2.3e-20 72.9 0.5 1.4e-15 57.2 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.6 EDO03287.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 DALR domain Na_H_Exchanger PF00999.16 EDO03289.1 - 1.6e-55 188.2 19.6 2.1e-55 187.8 13.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YIEGIA PF14045.1 EDO03289.1 - 0.19 10.3 0.4 0.3 9.6 0.3 1.2 1 0 0 1 1 1 0 YIEGIA protein Na_H_Exchanger PF00999.16 EDO03290.1 - 2.6e-29 101.9 44.6 4.8e-21 74.7 18.0 3.2 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family p450 PF00067.17 EDO03291.1 - 6.3e-24 84.3 0.0 8.4e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MBOAT PF03062.14 EDO03291.1 - 2.4e-05 23.6 0.1 5.7e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PGP_phosphatase PF09419.5 EDO03292.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Cellulase PF00150.13 EDO03294.1 - 3e-18 66.0 2.5 3e-18 66.0 1.8 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) COOH-NH2_lig PF14395.1 EDO03294.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 2OG-FeII_Oxy PF03171.15 EDO03295.1 - 0.0048 17.1 0.0 0.0093 16.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 EDO03296.1 - 7.6e-66 221.2 0.2 7.6e-66 221.2 0.1 1.6 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 EDO03296.1 - 0.0083 16.2 0.1 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Fascin domain Sel1 PF08238.7 EDO03297.1 - 2.1e-41 139.4 49.0 2.2e-06 28.1 0.2 13.6 13 1 0 13 13 13 9 Sel1 repeat WD40 PF00400.27 EDO03297.1 - 7.7e-08 31.9 1.4 0.0017 18.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_16 PF13432.1 EDO03297.1 - 0.00074 20.1 26.8 0.18 12.5 0.5 8.0 5 2 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO03297.1 - 0.011 15.4 1.7 0.011 15.4 1.2 5.7 4 4 2 6 6 6 0 TPR repeat HLH PF00010.21 EDO03298.1 - 3.6e-09 36.1 0.0 5.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.9 EDO03300.1 - 1.2e-48 164.8 0.0 1.6e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Het-C PF07217.6 EDO03301.1 - 1.5e-251 835.8 0.0 2.4e-251 835.2 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C HMG_box PF00505.14 EDO03302.1 - 1.7e-11 44.1 0.0 3.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO03302.1 - 7.2e-05 23.0 0.4 0.00024 21.4 0.0 2.2 2 0 0 2 2 2 1 HMG-box domain Glyco_hydro_71 PF03659.9 EDO03303.1 - 1.1e-68 231.4 2.0 1.5e-68 231.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.13 EDO03305.1 - 4.5e-21 74.8 0.0 7.8e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO03305.1 - 1.8e-08 34.1 9.4 3.3e-08 33.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_12 PF08242.7 EDO03306.1 - 3.4e-18 65.9 0.0 3.2e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EDO03306.1 - 6e-14 52.0 0.2 1.4e-13 50.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EDO03306.1 - 2.9e-13 49.8 0.0 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03306.1 - 1.9e-10 40.5 0.0 1.5e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO03306.1 - 1e-09 38.7 0.0 1.3e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03306.1 - 9e-08 32.6 0.0 3.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03306.1 - 7.3e-06 26.2 0.0 2.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO03306.1 - 9.7e-05 21.5 0.0 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EDO03306.1 - 0.00012 21.5 0.0 0.00036 20.0 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EDO03306.1 - 0.0002 21.3 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EDO03306.1 - 0.0035 16.8 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EDO03306.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ketoacyl-synt PF00109.21 EDO03307.1 - 2e-72 243.7 0.1 5.8e-72 242.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EDO03307.1 - 1.9e-07 30.3 0.0 4.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EDO03307.1 - 0.0022 17.6 3.7 0.0029 17.2 0.6 2.6 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Collagen PF01391.13 EDO03307.1 - 2.2 7.9 4.3 0.71 9.4 0.5 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) FSH1 PF03959.8 EDO03308.1 - 9.2e-26 90.5 0.0 1.3e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDO03308.1 - 1.1e-06 28.6 5.7 6.5e-06 26.1 4.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO03308.1 - 3.6e-06 26.8 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO03308.1 - 1.3e-05 24.7 0.0 0.017 14.5 0.0 2.9 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EDO03308.1 - 0.0078 15.8 0.2 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold EthD PF07110.6 EDO03310.1 - 0.0029 18.4 0.0 0.044 14.7 0.0 2.0 1 1 0 1 1 1 1 EthD domain PBP PF01161.15 EDO03311.1 - 2.5e-19 69.5 0.4 3.1e-19 69.2 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MFS_1 PF07690.11 EDO03312.1 - 2.1e-40 138.5 30.3 2.1e-40 138.5 21.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO03312.1 - 1.7e-15 56.6 0.4 1.7e-15 56.6 0.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EDO03312.1 - 0.035 12.1 1.7 0.035 12.1 0.3 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_1 PF01979.15 EDO03314.1 - 1.8e-64 218.4 3.9 3.2e-64 217.7 2.3 1.7 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 EDO03314.1 - 6.6e-55 184.4 5.6 2.1e-54 182.8 1.9 2.4 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EDO03314.1 - 5e-42 141.7 0.2 1.4e-41 140.3 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EDO03314.1 - 6e-32 109.6 0.0 1.3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EDO03314.1 - 1.8e-06 27.6 2.4 4.8e-06 26.2 1.7 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDO03314.1 - 0.00024 20.4 0.6 0.0007 18.9 0.1 1.9 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EDO03314.1 - 0.0099 15.4 0.0 0.084 12.4 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase zf-RING_2 PF13639.1 EDO03315.1 - 3.8e-14 52.2 5.0 7.7e-14 51.2 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO03315.1 - 4.9e-08 32.8 5.3 1.1e-07 31.7 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO03315.1 - 5.6e-07 29.1 4.3 1.1e-06 28.2 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO03315.1 - 2.1e-06 27.3 3.6 3.8e-06 26.5 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDO03315.1 - 6.2e-06 26.2 1.7 1.5e-05 24.9 1.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDO03315.1 - 7.3e-06 25.5 2.0 1.4e-05 24.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO03315.1 - 0.00038 20.2 1.5 0.00095 18.9 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EDO03315.1 - 0.003 17.2 1.9 0.0062 16.2 1.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_4 PF15227.1 EDO03315.1 - 0.0032 17.3 7.1 0.0062 16.3 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDO03315.1 - 0.015 14.9 4.5 0.054 13.2 3.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EDO03315.1 - 0.039 13.5 2.7 0.075 12.6 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EDO03315.1 - 0.1 12.6 1.0 0.2 11.7 0.7 1.5 1 0 0 1 1 1 0 RING-variant domain Rtf2 PF04641.7 EDO03315.1 - 0.2 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.1 EDO03315.1 - 0.24 11.1 1.4 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 EDO03315.1 - 0.32 10.5 5.0 0.76 9.3 3.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 EDO03315.1 - 8.5 6.0 7.8 19 4.8 1.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ada3 PF10198.4 EDO03316.1 - 5.8e-46 155.4 0.3 5.8e-46 155.4 0.2 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Lactamase_B_2 PF12706.2 EDO03318.1 - 5.8e-09 35.7 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EDO03318.1 - 1.2e-06 28.4 0.0 3.5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 EDO03318.1 - 0.0086 15.8 0.0 0.059 13.1 0.0 2.5 1 1 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase DUF1656 PF07869.7 EDO03319.1 - 0.41 10.4 2.0 0.64 9.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Bromodomain PF00439.20 EDO03320.1 - 1.4e-19 69.7 1.0 3e-19 68.7 0.7 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EDO03320.1 - 4.6e-10 39.3 0.0 9.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO03320.1 - 8e-10 38.7 0.1 1.6e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO03320.1 - 0.01 15.7 0.1 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO03320.1 - 0.16 11.7 0.1 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Rad1 PF02144.11 EDO03321.1 - 1.9e-75 253.2 0.0 2.3e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Spore_III_AF PF09581.5 EDO03322.1 - 3.3 7.5 9.3 1.1 9.0 2.6 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF4140 PF13600.1 EDO03323.1 - 0.0087 16.4 0.1 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.1 EDO03323.1 - 0.012 15.9 0.4 0.031 14.5 0.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Mei5 PF10376.4 EDO03323.1 - 0.015 14.8 14.6 0.045 13.2 10.2 1.8 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF4407 PF14362.1 EDO03323.1 - 2.5 6.9 9.8 11 4.8 6.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_2b PF00587.20 EDO03324.1 - 2.4e-48 164.0 0.0 3.6e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO03324.1 - 2.7e-09 36.8 0.4 6e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 EDO03324.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF325 PF03804.8 EDO03326.1 - 0.053 13.2 0.1 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Viral domain of unknown function Fungal_trans_2 PF11951.3 EDO03327.1 - 1.1e-12 47.2 0.0 1.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO03327.1 - 4.8e-08 32.7 5.2 8.5e-08 31.9 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDO03328.1 - 2.4e-24 85.6 0.0 2.7e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain YoqO PF14037.1 EDO03330.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 YoqO-like protein Pyr_redox_2 PF07992.9 EDO03331.1 - 7.6e-13 48.7 0.0 1.5e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO03331.1 - 2.3e-10 40.6 0.0 4.6e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO03331.1 - 9e-08 32.4 0.3 0.002 18.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase RVT_2 PF07727.9 EDO03332.1 - 3e-50 170.4 0.0 3.5e-49 166.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO03332.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO03332.1 - 0.00017 21.1 0.7 0.0005 19.6 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDO03332.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Fungal_trans_2 PF11951.3 EDO03335.1 - 7.2e-10 38.0 0.9 9.2e-10 37.6 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EDO03336.1 - 1.1e-48 165.6 12.2 1.7e-48 165.0 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EDO03336.1 - 0.0024 17.5 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Abhydrolase_6 PF12697.2 EDO03337.1 - 9.5e-08 32.1 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO03337.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EDO03337.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 EDO03337.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EDO03337.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family PhoPQ_related PF10142.4 EDO03337.1 - 0.039 12.4 0.0 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 EDO03337.1 - 0.093 12.1 0.1 0.2 11.1 0.0 1.6 1 1 0 2 2 2 0 Serine hydrolase (FSH1) AXE1 PF05448.7 EDO03337.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S10 PF00450.17 EDO03337.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DiS_P_DiS PF06750.8 EDO03338.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF2985 PF11204.3 EDO03339.1 - 6.4e-30 102.7 4.3 6.4e-30 102.7 3.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) F-box-like PF12937.2 EDO03340.1 - 0.00013 21.6 0.3 0.00037 20.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EDO03340.1 - 0.088 13.0 0.1 19 6.0 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat JAB PF01398.16 EDO03341.1 - 9.4e-35 118.8 0.0 1.8e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDO03341.1 - 2.6e-27 95.1 1.6 3.6e-27 94.7 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EDO03341.1 - 6.1e-09 35.3 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EDO03342.1 - 3e-79 266.5 0.0 5.5e-79 265.6 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L14 PF00238.14 EDO03343.1 - 3e-32 110.9 0.0 3.3e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Zip PF02535.17 EDO03344.1 - 1.1e-46 159.3 1.3 1.8e-46 158.6 0.9 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Methyltransf_23 PF13489.1 EDO03347.1 - 4.1e-22 78.6 0.0 6.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03347.1 - 6.3e-14 51.8 0.0 1.6e-12 47.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO03347.1 - 8e-10 39.0 0.0 1.8e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03347.1 - 1.1e-09 38.8 0.0 3.5e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03347.1 - 2.6e-09 37.4 0.0 2.8e-08 34.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDO03347.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EDO03347.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EDO03347.1 - 0.014 15.3 0.0 0.071 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03347.1 - 0.021 15.1 0.0 0.079 13.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDO03347.1 - 0.025 13.6 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EDO03347.1 - 0.034 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EDO03347.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 EDO03347.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Tannase PF07519.6 EDO03348.1 - 0.002 16.9 0.0 0.002 16.9 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Glyco_hydro_28 PF00295.12 EDO03351.1 - 1.7e-52 178.3 6.7 3e-52 177.6 4.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Fork_head PF00250.13 EDO03353.1 - 1e-15 57.5 0.2 2.3e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EDO03354.1 - 1.7e-67 226.4 4.2 3.1e-67 225.5 2.9 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EDO03354.1 - 1.9e-54 182.5 3.8 3.3e-54 181.7 2.6 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EDO03354.1 - 0.003 17.4 1.9 0.88 9.5 0.1 2.6 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1087) dNK PF01712.14 EDO03354.1 - 0.063 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Deoxynucleoside kinase PMSR PF01625.16 EDO03355.1 - 1.2e-60 203.9 2.6 1.4e-60 203.7 1.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PRP3 PF08572.5 EDO03355.1 - 0.13 11.6 0.9 0.17 11.2 0.6 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) cNMP_binding PF00027.24 EDO03357.1 - 5.7e-35 119.0 0.0 2.2e-18 65.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EDO03357.1 - 2.1e-08 33.3 11.2 1.2 9.4 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.1 EDO03357.1 - 7.6e-08 31.9 1.4 0.0069 16.1 0.2 4.6 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EDO03357.1 - 1.3e-07 30.6 2.4 17 5.9 0.0 7.6 6 2 1 7 7 7 1 Leucine Rich Repeat Ste50p-SAM PF09235.5 EDO03357.1 - 0.04 13.9 1.0 35 4.5 0.1 3.8 2 1 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EDO03357.1 - 0.2 12.0 12.3 31 5.3 0.1 6.7 8 0 0 8 8 8 0 Leucine rich repeat Bax1-I PF01027.15 EDO03358.1 - 4e-34 118.0 15.0 4e-34 118.0 10.4 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Acetyltransf_1 PF00583.19 EDO03360.1 - 2.1e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO03360.1 - 0.046 13.8 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBR PF01485.16 EDO03361.1 - 7.3e-12 44.9 33.8 2e-06 27.5 5.1 2.3 2 0 0 2 2 2 2 IBR domain HIG_1_N PF04588.8 EDO03362.1 - 1.8e-08 34.0 2.5 3.6e-08 33.0 1.7 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region zf-H2C2_2 PF13465.1 EDO03364.1 - 3.7e-05 23.8 6.2 0.0032 17.6 0.7 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO03364.1 - 0.00019 21.5 10.9 0.027 14.7 0.6 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO03364.1 - 0.0082 16.4 16.5 0.056 13.8 1.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDO03364.1 - 0.011 15.8 7.7 0.019 15.0 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Tetraspannin PF00335.15 EDO03364.1 - 0.13 11.5 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Tetraspanin family zf-CHCC PF10276.4 EDO03364.1 - 1.3 8.9 5.7 0.55 10.1 1.6 2.1 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_6 PF13912.1 EDO03364.1 - 3.9 7.5 8.8 0.13 12.2 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EDO03364.1 - 6.7 6.5 8.5 0.46 10.2 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger AT_hook PF02178.14 EDO03370.1 - 9.9e-06 24.6 42.8 0.089 12.5 0.4 6.4 5 0 0 5 5 5 5 AT hook motif Mitofilin PF09731.4 EDO03370.1 - 1.4 7.4 4.5 1.8 7.1 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-met2 PF12907.2 EDO03371.1 - 1.8e-15 56.6 1.6 2.6e-15 56.0 1.1 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EDO03371.1 - 1.7e-05 25.4 7.7 3.6e-05 24.4 5.3 1.6 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_6 PF13912.1 EDO03371.1 - 0.1 12.5 0.5 0.16 11.8 0.1 1.5 2 0 0 2 2 2 0 C2H2-type zinc finger DIOX_N PF14226.1 EDO03372.1 - 3.7e-32 111.2 0.0 1.7e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDO03372.1 - 1.5e-15 57.2 0.0 3.1e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EDO03373.1 - 0.00022 20.9 4.7 0.0014 18.4 0.1 4.5 7 0 0 7 7 7 1 WD domain, G-beta repeat DUF2555 PF10742.4 EDO03373.1 - 0.088 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) RNA_pol_N PF01194.12 EDO03374.1 - 6.6e-10 38.8 4.4 3.2e-09 36.6 1.9 2.4 2 0 0 2 2 2 1 RNA polymerases N / 8 kDa subunit DLIC PF05783.6 EDO03375.1 - 0.29 9.7 1.9 0.59 8.7 1.3 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NPR2 PF06218.6 EDO03377.1 - 6.7e-141 469.8 10.3 3.4e-117 391.7 5.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 EDO03377.1 - 0.024 13.1 1.7 1.8 7.0 0.0 2.8 2 1 1 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_16 PF10294.4 EDO03378.1 - 2.9e-19 69.1 0.0 2.6e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase MTS PF05175.9 EDO03378.1 - 0.00068 19.0 0.0 0.0028 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EDO03378.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03378.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03378.1 - 0.1 13.1 0.2 0.31 11.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Tox-REase-7 PF15649.1 EDO03380.1 - 1.8 8.7 8.2 96 3.2 5.7 2.5 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 7 HET PF06985.6 EDO03381.1 - 2.3e-26 92.5 0.6 7.5e-26 90.9 0.0 2.2 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Kelch_3 PF13415.1 EDO03383.1 - 4.4e-40 134.9 14.4 8e-09 35.4 0.0 6.7 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO03383.1 - 1e-39 134.0 17.2 2.8e-10 39.8 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EDO03383.1 - 2.7e-36 122.8 12.6 1.2e-06 27.9 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EDO03383.1 - 1.3e-35 120.7 13.5 3.5e-07 30.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EDO03383.1 - 8e-34 114.4 14.2 3.6e-07 30.0 0.0 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EDO03383.1 - 9.5e-30 101.2 13.8 4.5e-06 26.2 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Dus PF01207.12 EDO03384.1 - 1.1e-40 139.3 0.0 2.6e-29 102.0 0.0 2.9 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Kin17_mid PF10357.4 EDO03384.1 - 0.0089 15.6 1.4 0.027 14.0 1.0 1.8 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-CCCH PF00642.19 EDO03384.1 - 0.1 12.2 4.6 2.4 7.9 0.6 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 EDO03385.1 - 5.7e-66 221.6 3.6 6.9e-66 221.3 2.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Tash_PEST PF07708.6 EDO03386.1 - 5.8 7.0 7.3 7.1 6.7 1.6 3.0 2 0 0 2 2 2 0 Tash protein PEST motif K167R PF08065.7 EDO03387.1 - 0.14 12.2 3.8 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 K167R (NUC007) repeat HEAT PF02985.17 EDO03393.1 - 1.5e-07 30.8 0.6 0.86 9.8 0.1 6.1 7 0 0 7 7 7 2 HEAT repeat CLASP_N PF12348.3 EDO03393.1 - 0.00047 19.5 0.6 0.0021 17.4 0.2 2.0 2 0 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.1 EDO03393.1 - 0.016 15.6 3.3 24 5.5 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat HsbA PF12296.3 EDO03393.1 - 0.023 14.5 1.6 1.8 8.4 0.2 2.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Syntaxin PF00804.20 EDO03393.1 - 0.047 13.8 3.1 0.18 12.0 2.2 2.0 1 0 0 1 1 1 0 Syntaxin APG6 PF04111.7 EDO03393.1 - 0.091 11.7 12.2 0.025 13.6 5.7 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EDO03393.1 - 0.094 12.3 8.2 0.25 10.9 5.7 1.7 1 0 0 1 1 1 0 IncA protein Mod_r PF07200.8 EDO03393.1 - 5.1 7.0 16.4 0.47 10.3 7.7 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.17 EDO03393.1 - 9.9 6.2 14.5 4.4 7.3 4.7 3.4 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.27 EDO03394.1 - 1.2e-73 240.6 16.3 6.9e-12 44.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDO03394.1 - 1.4e-08 33.4 0.9 0.00032 18.9 0.2 4.3 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO03394.1 - 6.1e-05 21.9 0.1 0.19 10.4 0.0 3.4 2 1 0 3 3 3 3 Nup133 N terminal like DDE_1 PF03184.14 EDO03396.1 - 1.8e-52 177.6 0.0 3.1e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO03396.1 - 1.1e-09 37.6 0.0 2.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO03396.1 - 7.2e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03396.1 - 5.2e-06 26.1 1.0 2.5e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain CH PF00307.26 EDO03401.1 - 1.8e-09 37.6 0.0 3.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain XPG_I PF00867.13 EDO03402.1 - 2.9e-24 84.9 0.0 6.8e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO03402.1 - 3e-08 33.8 0.0 7.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDO03402.1 - 0.0097 15.4 0.0 0.03 13.8 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing Actin PF00022.14 EDO03403.1 - 1.4e-21 76.4 0.0 1.3e-19 69.9 0.0 2.6 2 1 0 2 2 2 2 Actin WLM PF08325.5 EDO03412.1 - 1.3e-55 188.2 1.5 2.6e-55 187.2 0.1 1.9 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 EDO03412.1 - 0.0045 16.0 4.0 0.0045 16.0 2.8 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EDO03412.1 - 0.009 15.8 11.5 0.019 14.7 8.0 1.6 1 0 0 1 1 1 1 Double zinc ribbon SprT-like PF10263.4 EDO03412.1 - 0.06 12.9 4.4 0.08 12.5 0.0 2.4 2 0 0 2 2 2 0 SprT-like family DUF3279 PF11682.3 EDO03412.1 - 5.7 6.5 10.2 13 5.3 4.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) DUF1776 PF08643.5 EDO03413.1 - 4e-109 364.3 0.0 5e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavi_M PF01004.14 EDO03413.1 - 0.039 13.3 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M zf-CCCH PF00642.19 EDO03414.1 - 4e-24 83.7 32.2 6.6e-07 28.8 0.2 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO03414.1 - 8.3e-05 22.4 5.6 0.013 15.4 0.0 5.8 7 0 0 7 7 7 3 Zinc finger C-x8-C-x5-C-x3-H type Glyco_hydro_18 PF00704.23 EDO03416.1 - 1.8e-73 247.9 0.0 2.1e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.7 EDO03417.1 - 1.3e-101 340.1 2.3 2.2e-101 339.4 1.6 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EDO03417.1 - 1.9e-05 23.7 7.4 3.4e-05 22.9 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EDO03417.1 - 0.0091 14.2 5.0 0.022 12.9 3.4 1.6 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.6 EDO03417.1 - 0.031 12.9 3.3 0.066 11.8 2.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Bul1_C PF04426.7 EDO03417.1 - 0.062 12.4 0.6 0.15 11.1 0.4 1.6 1 0 0 1 1 1 0 Bul1 C terminus Pyr_redox_2 PF07992.9 EDO03418.1 - 1.5e-27 96.7 0.7 2.1e-27 96.3 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO03418.1 - 1.5e-17 63.7 4.3 4.7e-16 58.9 0.5 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO03418.1 - 3.1e-09 37.2 0.4 3.1e-06 27.3 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EDO03418.1 - 1.3e-05 25.3 0.6 0.0013 18.9 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 EDO03418.1 - 0.00012 21.1 2.9 0.66 8.8 0.0 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO03418.1 - 0.0024 17.8 0.3 1.8 8.6 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO03418.1 - 0.0029 16.5 0.1 0.046 12.6 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EDO03418.1 - 0.017 13.6 0.8 3.8 5.8 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 EDO03418.1 - 0.018 14.1 0.3 0.16 11.0 0.1 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EDO03418.1 - 0.023 14.4 0.9 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EDO03418.1 - 0.03 12.9 0.2 0.42 9.1 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EDO03418.1 - 0.045 12.7 0.6 5.2 6.0 0.0 2.5 2 1 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EDO03418.1 - 0.049 13.7 0.8 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EDO03418.1 - 0.059 12.2 7.7 7 5.3 0.3 3.9 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EDO03418.1 - 0.87 8.3 6.3 1 8.1 0.4 3.0 2 1 0 3 3 3 0 FAD binding domain Glyco_transf_28 PF03033.15 EDO03420.1 - 8.4e-22 77.4 0.1 2e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EDO03420.1 - 1.2e-05 24.1 0.1 2.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EDO03420.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EDO03420.1 - 0.0077 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Sec61_beta PF03911.11 EDO03421.1 - 6.9e-21 73.7 1.5 9.2e-21 73.3 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.13 EDO03422.1 - 1.4e-50 171.0 0.2 2e-50 170.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 EDO03423.1 - 4.7e-97 324.4 0.0 4.7e-97 324.4 0.0 1.9 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDO03423.1 - 2.6e-14 53.7 0.0 5.7e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Ribosomal_L18ae PF01775.12 EDO03424.1 - 1.8e-59 199.0 1.2 2.3e-59 198.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 EDO03425.1 - 3.3e-10 40.2 0.0 7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 EDO03425.1 - 0.0039 16.8 0.1 0.014 15.0 0.1 1.9 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EDO03425.1 - 0.021 14.6 2.8 0.03 14.2 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO03425.1 - 0.03 13.9 1.1 0.15 11.6 0.7 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO03425.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat BTB PF00651.26 EDO03426.1 - 4.7e-08 33.0 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Transformer PF06495.6 EDO03426.1 - 0.008 16.0 2.3 0.013 15.3 1.6 1.4 1 0 0 1 1 1 1 Fruit fly transformer protein Abhydrolase_5 PF12695.2 EDO03427.1 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO03427.1 - 2.5e-07 30.8 0.0 5e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO03427.1 - 0.00097 18.7 0.0 0.3 10.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EDO03427.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EDO03427.1 - 0.066 12.6 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LRR_4 PF12799.2 EDO03429.1 - 1.3e-44 149.1 55.0 1.6e-09 37.1 2.3 7.5 2 2 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO03429.1 - 1e-22 79.6 38.9 4.4e-08 32.7 3.0 5.3 3 2 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EDO03429.1 - 2.4e-15 54.2 27.7 0.16 12.1 0.0 11.9 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_7 PF13504.1 EDO03429.1 - 1.5e-14 51.5 14.5 0.36 11.2 0.0 10.2 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 EDO03429.1 - 2.9e-13 48.3 23.9 0.027 14.5 0.1 10.4 6 3 5 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 EDO03429.1 - 4.1e-10 39.4 10.3 0.00043 19.9 1.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeat Aldo_ket_red PF00248.16 EDO03430.1 - 2.1e-48 164.5 0.0 2.4e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fringe PF02434.11 EDO03431.1 - 6.5e-05 22.2 0.6 0.00051 19.3 0.4 1.9 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EDO03431.1 - 0.013 15.1 0.1 0.077 12.5 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase Glyco_trans_2_3 PF13632.1 EDO03432.1 - 6.7e-45 153.1 3.4 6.7e-45 153.1 2.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EDO03432.1 - 3.7e-07 29.9 0.5 3e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDO03432.1 - 1.9e-06 27.8 0.0 3.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDO03432.1 - 0.0002 20.7 0.0 0.00044 19.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 EDO03434.1 - 8.1e-21 74.1 1.1 1.3e-20 73.4 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAN_4 PF14295.1 EDO03436.1 - 9.8e-05 21.9 4.5 0.038 13.7 0.1 3.2 3 0 0 3 3 3 2 PAN domain Prot_inhib_II PF02428.10 EDO03436.1 - 1.1 9.3 9.0 1.1 9.3 0.1 3.0 3 0 0 3 3 3 0 Potato type II proteinase inhibitor family Utp11 PF03998.8 EDO03438.1 - 4.8e-47 160.8 9.4 5.3e-47 160.6 6.5 1.0 1 0 0 1 1 1 1 Utp11 protein Cmc1 PF08583.5 EDO03439.1 - 1.7e-17 62.8 3.1 1.7e-17 62.8 2.1 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EDO03439.1 - 0.0052 16.6 0.3 0.78 9.7 0.1 2.3 2 0 0 2 2 2 2 CHCH domain NDUF_B7 PF05676.8 EDO03439.1 - 0.074 12.4 1.3 0.15 11.4 0.6 1.8 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.3 EDO03439.1 - 1.6 8.9 7.7 4 7.6 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) SET PF00856.23 EDO03440.1 - 5.3e-12 46.3 0.0 2.8e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 SET domain Peroxidase_2 PF01328.12 EDO03444.1 - 8.8e-10 37.7 1.8 2.8e-09 36.0 1.2 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.27 EDO03445.1 - 2.8e-14 52.3 10.7 1.1e-08 34.5 0.6 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EDO03445.1 - 5.3e-06 26.2 0.1 0.02 14.5 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EDO03445.1 - 1.9e-05 23.1 0.1 0.00024 19.5 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EDO03445.1 - 0.046 13.1 0.3 3 7.2 0.0 2.6 2 1 1 3 3 3 0 PQQ-like domain IKI3 PF04762.7 EDO03445.1 - 0.13 10.0 0.3 5.8 4.5 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Pyr_redox_2 PF07992.9 EDO03446.1 - 5.5e-34 117.8 1.0 7.8e-34 117.3 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDO03446.1 - 7.7e-29 99.9 0.2 1.5e-28 98.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDO03446.1 - 1.8e-14 53.9 0.4 1.8e-14 53.9 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO03446.1 - 2.9e-07 30.7 0.0 5.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO03446.1 - 0.00021 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EDO03446.1 - 0.05 13.2 0.2 0.05 13.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PROCT PF08084.6 EDO03446.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain 2-Hacid_dh_C PF02826.14 EDO03446.1 - 0.5 9.4 3.2 1.7 7.7 0.1 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EDO03446.1 - 1.3 7.8 9.5 0.024 13.5 1.5 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase RNA_pol_Rpb1_1 PF04997.7 EDO03447.1 - 1.7e-114 382.6 0.0 3.5e-114 381.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EDO03447.1 - 1e-100 336.6 0.1 2.3e-100 335.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDO03447.1 - 1e-70 237.0 0.0 2.8e-70 235.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EDO03447.1 - 1.1e-54 185.0 2.7 2e-54 184.1 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EDO03447.1 - 9.4e-46 155.4 0.0 2e-45 154.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EDO03447.1 - 3.8e-42 143.2 8.2 3.8e-42 143.2 5.7 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EDO03447.1 - 5.9e-37 125.7 0.1 1.4e-36 124.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EDO03447.1 - 3.8e-10 39.0 195.4 0.027 14.5 8.6 14.2 8 3 3 14 14 14 8 RNA polymerase Rpb1 C-terminal repeat Fungal_trans PF04082.13 EDO03450.1 - 2.8e-09 36.2 0.1 5.6e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO03450.1 - 2.9e-07 30.2 9.1 5.8e-07 29.3 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.16 EDO03451.1 - 8.7e-31 106.7 0.0 8.7e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDO03451.1 - 7.9e-21 74.0 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDO03451.1 - 1.8e-09 37.6 0.0 3.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AIF-MLS PF14962.1 EDO03451.1 - 0.012 15.2 0.3 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence FAD_binding_9 PF08021.6 EDO03451.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain CorA PF01544.13 EDO03452.1 - 0.22 10.4 2.3 0.95 8.4 0.2 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Transket_pyr PF02779.19 EDO03453.1 - 6.2e-63 211.4 0.0 1e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EDO03453.1 - 5.6e-56 189.4 0.0 8.4e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 EDO03454.1 - 6.6e-26 89.7 0.0 4.2e-25 87.2 0.0 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EDO03454.1 - 1.1e-24 85.9 3.3 1e-13 50.7 0.2 3.0 2 0 0 2 2 2 2 BSD domain RHS_repeat PF05593.9 EDO03456.1 - 1.1e-07 31.8 56.6 0.081 13.1 0.1 13.5 15 1 0 15 15 15 7 RHS Repeat Band_7 PF01145.20 EDO03459.1 - 1.7e-25 89.9 2.2 2.5e-25 89.3 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family eRF1_3 PF03465.10 EDO03459.1 - 0.029 14.6 0.5 0.51 10.6 0.3 2.3 1 1 0 1 1 1 0 eRF1 domain 3 p450 PF00067.17 EDO03462.1 - 1.2e-43 149.3 0.0 1.8e-43 148.7 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DDE_1 PF03184.14 EDO03464.1 - 1.2e-47 161.8 0.6 2.8e-47 160.6 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03464.1 - 6.6e-08 32.2 0.0 2.3e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO03464.1 - 0.14 12.1 6.1 0.33 10.9 4.2 1.7 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EDO03465.1 - 1.2e-40 139.3 34.1 1.2e-40 139.3 23.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO03465.1 - 5.9e-17 61.3 22.7 1.2e-16 60.4 15.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDO03465.1 - 4.6e-06 25.1 1.6 4.6e-06 25.1 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDO03465.1 - 0.022 12.8 3.3 0.88 7.5 0.0 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MM_CoA_mutase PF01642.17 EDO03466.1 - 0.11 10.6 0.1 0.1 10.7 0.1 1.0 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase DDE_1 PF03184.14 EDO03471.1 - 1.7e-51 174.4 0.0 4e-51 173.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03471.1 - 4.4e-10 39.2 1.0 1.2e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO03471.1 - 7.4e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO03471.1 - 0.0051 16.6 6.0 0.012 15.4 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDO03471.1 - 0.076 13.3 0.6 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DDE_1 PF03184.14 EDO03475.1 - 1.3e-49 168.3 0.0 2.7e-49 167.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO03475.1 - 6.8e-11 41.5 0.7 5.4e-10 38.6 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO03475.1 - 1.5e-07 31.0 0.1 6.9e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO03475.1 - 1.6e-06 27.9 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_37 PF13744.1 EDO03475.1 - 0.041 13.6 0.3 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDO03475.1 - 0.1 12.4 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 NUMOD1 domain 2-Hacid_dh_C PF02826.14 EDO03477.1 - 1.8e-47 160.7 0.0 9.8e-47 158.3 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO03477.1 - 9.7e-09 34.7 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDO03477.1 - 0.0082 15.9 0.1 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glt_symporter PF03616.9 EDO03477.1 - 0.03 12.8 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter ADH_N PF08240.7 EDO03478.1 - 2.5e-27 94.8 1.2 2.5e-27 94.8 0.8 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO03478.1 - 5.2e-16 58.3 0.0 8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO03478.1 - 0.12 13.2 0.0 0.21 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ATP-synt_G PF04718.10 EDO03479.1 - 1.2e-32 112.6 0.4 2.9e-31 108.1 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF4010 PF13194.1 EDO03479.1 - 0.059 12.6 0.4 0.094 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) EspB PF05802.6 EDO03479.1 - 0.2 10.5 5.6 0.13 11.2 2.4 1.7 2 1 0 2 2 2 0 Enterobacterial EspB protein MeMO_Hyd_G PF02964.11 EDO03480.1 - 0.071 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain DLH PF01738.13 EDO03481.1 - 5.4e-24 84.6 0.0 6.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDO03481.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDO03481.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EDO03481.1 - 0.039 13.3 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EDO03481.1 - 0.12 11.6 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family CDP-OH_P_transf PF01066.16 EDO03482.1 - 1.1e-17 64.1 9.0 2.7e-17 62.8 6.2 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PcfK PF14058.1 EDO03483.1 - 0.91 9.6 5.4 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 PcfK-like protein HTH_38 PF13936.1 EDO03484.1 - 0.081 12.4 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SpecificRecomb PF10136.4 EDO03485.1 - 0.074 11.0 0.0 0.077 11.0 0.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase P16-Arc PF04699.9 EDO03490.1 - 4.5e-44 150.1 0.0 5.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Aa_trans PF01490.13 EDO03493.1 - 8.6e-26 90.3 30.6 8.6e-26 90.3 21.2 2.2 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Imm45 PF15603.1 EDO03494.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 45 Glyco_hydro_2 PF00703.16 EDO03496.1 - 6.1e-12 45.9 0.5 2e-11 44.3 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EDO03496.1 - 6.8e-10 38.7 0.2 1.7e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EDO03496.1 - 6.6e-06 25.2 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain ADH_N PF08240.7 EDO03497.1 - 7.8e-31 106.0 0.1 1.6e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO03497.1 - 7e-25 87.0 1.5 9.6e-25 86.6 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO03497.1 - 0.00069 20.5 0.0 0.002 19.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EDO03497.1 - 0.023 15.2 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EDO03497.1 - 0.024 14.2 0.1 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein AlaDh_PNT_C PF01262.16 EDO03497.1 - 0.026 14.0 0.2 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EDO03497.1 - 0.046 13.5 0.9 0.085 12.6 0.6 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.9 EDO03497.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO03497.1 - 0.2 10.1 1.3 0.28 9.6 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Polyketide_cyc PF03364.15 EDO03498.1 - 1.8e-22 79.6 0.0 6.2e-22 77.9 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.17 EDO03499.1 - 3.6e-54 184.0 0.0 4.8e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-patch_2 PF12656.2 EDO03500.1 - 1.1e-22 79.7 0.4 1.1e-22 79.7 0.3 3.9 4 0 0 4 4 4 1 DExH-box splicing factor binding site PRP38_assoc PF12871.2 EDO03500.1 - 0.0071 16.8 33.0 0.0071 16.8 22.8 3.7 3 1 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HSA PF07529.8 EDO03501.1 - 7.6e-21 73.6 1.6 7.6e-21 73.6 1.1 4.0 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EDO03501.1 - 9e-13 48.1 0.8 9e-13 48.1 0.6 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO03501.1 - 0.0039 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain INSIG PF07281.7 EDO03502.1 - 5.8e-54 182.3 0.1 7.8e-54 181.9 0.1 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WD40 PF00400.27 EDO03504.1 - 1e-10 41.0 0.0 0.0072 16.1 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat CMAS PF02353.15 EDO03505.1 - 3.5e-63 213.2 0.0 4.3e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDO03505.1 - 2.3e-13 50.1 0.0 4.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO03505.1 - 3.4e-09 37.0 0.0 6.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03505.1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03505.1 - 8.4e-05 22.8 0.0 0.00024 21.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03505.1 - 0.00017 22.1 0.0 0.00042 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03505.1 - 0.00029 21.2 0.1 0.0015 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO03505.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EDO03505.1 - 0.0057 16.6 0.0 0.02 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EDO03505.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EDO03505.1 - 0.017 14.5 0.0 0.04 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain EF-hand_4 PF12763.2 EDO03506.1 - 5.7e-25 87.0 0.0 1.6e-12 47.1 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EDO03506.1 - 6.9e-07 29.2 37.9 6.9e-07 29.2 26.3 8.7 4 3 3 7 7 7 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EDO03506.1 - 0.00052 20.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO03506.1 - 0.0025 17.0 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EDO03506.1 - 0.0083 15.9 0.1 13 5.9 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EDO03506.1 - 0.023 14.2 0.1 35 4.1 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain pair Dabb PF07876.7 EDO03506.1 - 0.065 13.6 0.1 5.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain Endomucin PF07010.7 EDO03508.1 - 0.29 10.4 2.1 0.45 9.7 1.5 1.2 1 0 0 1 1 1 0 Endomucin Abhydrolase_3 PF07859.8 EDO03509.1 - 7.8e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO03509.1 - 5.6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO03509.1 - 4.5e-05 22.7 0.0 7.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDO03509.1 - 4.8e-05 22.8 0.0 9.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EDO03509.1 - 0.00022 19.8 0.0 0.00078 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EDO03509.1 - 0.0009 19.1 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EDO03509.1 - 0.0016 17.7 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.23 EDO03509.1 - 0.02 13.5 0.0 0.066 11.9 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.3 EDO03509.1 - 0.032 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2424 PF10340.4 EDO03509.1 - 0.071 11.7 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PARP PF00644.15 EDO03513.1 - 7.7e-12 45.0 0.1 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EDO03514.1 - 2.2e-11 43.3 0.0 4e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO03514.1 - 5.1e-05 23.0 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO03514.1 - 0.002 17.9 0.0 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain Carb_anhydrase PF00194.16 EDO03515.1 - 9.4e-21 73.9 1.8 1.9e-19 69.6 1.2 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Sds3 PF08598.6 EDO03516.1 - 1.3e-76 256.7 1.9 2.9e-76 255.5 1.3 1.6 1 1 0 1 1 1 1 Sds3-like Fungal_trans PF04082.13 EDO03517.1 - 1.3e-18 66.8 0.0 2.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleo_P87 PF07267.6 EDO03518.1 - 0.41 9.2 3.3 0.43 9.2 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAF-1_p150 PF11600.3 EDO03518.1 - 1.2 8.4 6.0 1.8 7.8 4.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3446 PF11928.3 EDO03518.1 - 2.3 8.4 11.5 0.34 11.1 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) tRNA-synt_2c PF01411.14 EDO03520.1 - 2.2e-175 584.1 5.0 2.2e-175 584.1 3.5 2.8 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDO03520.1 - 4.1e-16 58.5 0.5 9.3e-16 57.4 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EDO03520.1 - 0.019 14.6 1.5 0.065 12.9 1.0 2.1 1 0 0 1 1 1 0 DHHA1 domain FIST PF08495.5 EDO03520.1 - 0.027 13.6 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 FIST N domain XPC-binding PF09280.6 EDO03520.1 - 0.23 10.9 0.1 0.58 9.6 0.0 1.7 1 0 0 1 1 1 0 XPC-binding domain RCR PF12273.3 EDO03522.1 - 3.3e-18 66.5 5.6 4e-18 66.2 3.9 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CcmD PF04995.9 EDO03522.1 - 0.045 13.4 0.3 0.045 13.4 0.2 1.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Vps8 PF12816.2 EDO03523.1 - 1e-75 253.2 0.2 3.8e-75 251.4 0.0 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EDO03523.1 - 0.00029 20.4 0.6 0.18 11.3 0.0 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.1 EDO03523.1 - 0.008 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO03523.1 - 0.0088 15.7 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EDO03523.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.6 4 0 0 4 4 4 0 Ring finger domain zf-RING_5 PF14634.1 EDO03523.1 - 0.046 13.4 0.1 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3752 PF12572.3 EDO03524.1 - 9.1e-47 158.9 7.6 9.1e-47 158.9 5.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Transp_cyt_pur PF02133.10 EDO03525.1 - 1.6e-44 152.2 37.0 2e-44 151.8 25.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pro_isomerase PF00160.16 EDO03529.1 - 4.3e-48 163.4 0.3 4.9e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.1 EDO03531.1 - 5.5e-14 51.7 6.3 8.6e-14 51.0 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO03531.1 - 7.4e-08 31.9 3.6 1.2e-07 31.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO03531.1 - 2.1e-07 30.9 2.5 4.4e-07 29.9 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO03531.1 - 3.5e-06 26.6 3.7 5.5e-06 26.0 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO03531.1 - 4.4e-05 23.4 5.1 7.3e-05 22.7 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO03531.1 - 5.6e-05 22.7 2.1 9.2e-05 22.0 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO03531.1 - 0.0046 16.7 2.9 0.013 15.3 2.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO03531.1 - 0.0059 16.1 5.4 0.0097 15.4 3.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDO03531.1 - 0.043 13.5 0.3 0.098 12.3 0.1 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EDO03531.1 - 0.14 11.8 5.3 0.25 11.0 3.7 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EDO03531.1 - 0.16 11.9 3.4 0.43 10.5 2.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EDO03531.1 - 0.2 11.5 4.6 0.53 10.1 3.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EDO03531.1 - 0.26 11.3 5.7 0.47 10.5 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Pex14_N PF04695.8 EDO03531.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.4 3 2 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prok-RING_1 PF14446.1 EDO03531.1 - 0.82 9.4 6.6 0.11 12.2 0.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 EDO03531.1 - 4.2 8.0 10.6 6.4 7.4 4.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TPR_11 PF13414.1 EDO03532.1 - 6.1e-60 198.7 26.7 3e-16 58.8 0.5 6.4 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EDO03532.1 - 7e-47 155.2 23.7 1e-07 31.2 0.4 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EDO03532.1 - 3e-39 129.7 23.8 3.1e-06 26.6 0.5 9.7 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 EDO03532.1 - 4.5e-22 78.1 4.9 1.8e-05 25.2 0.1 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDO03532.1 - 4.6e-22 77.7 13.3 2.2e-12 46.7 0.3 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO03532.1 - 1.7e-18 65.4 11.1 0.024 15.2 0.3 8.6 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDO03532.1 - 4.9e-18 63.4 25.0 0.00084 18.9 0.1 8.4 6 2 2 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDO03532.1 - 1.9e-14 53.7 13.5 3.4e-05 24.0 0.1 6.8 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDO03532.1 - 1.1e-12 47.0 8.7 0.61 10.4 0.0 8.5 8 2 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDO03532.1 - 2.3e-12 45.7 8.2 5.5e-05 22.6 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO03532.1 - 3.4e-10 39.6 2.2 0.0083 15.9 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO03532.1 - 5e-06 26.6 17.2 1.6 9.3 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO03532.1 - 1.4e-05 25.0 11.8 0.00022 21.3 1.5 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDO03532.1 - 2.2e-05 24.2 2.3 0.0031 17.3 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 EDO03532.1 - 0.026 14.3 4.8 1.9 8.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF982 PF06169.7 EDO03532.1 - 0.08 12.6 2.1 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF982) UPF0029 PF01205.14 EDO03532.1 - 0.47 10.1 2.8 0.32 10.6 0.3 2.0 2 0 0 2 2 1 0 Uncharacterized protein family UPF0029 Sec5 PF15469.1 EDO03532.1 - 0.48 10.1 4.8 1.2 8.8 0.5 3.1 2 1 1 3 3 3 0 Exocyst complex component Sec5 DUF357 PF04010.8 EDO03532.1 - 1 9.1 7.0 0.92 9.2 0.4 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF357) Pal1 PF08316.6 EDO03532.1 - 1.4 9.3 0.0 1.4 9.3 0.0 3.4 4 0 0 4 4 4 0 Pal1 cell morphology protein GIT_SHD PF08518.6 EDO03533.1 - 2.5e-23 81.1 5.0 2.8e-14 52.1 0.9 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Atg14 PF10186.4 EDO03533.1 - 10 4.9 29.3 1.1 8.0 2.7 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Ssu72 PF04722.8 EDO03534.1 - 2.3e-86 288.1 0.0 2.6e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 EDO03535.1 - 4.8e-09 35.4 0.0 8.9e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO03535.1 - 5.6e-09 35.4 0.2 1.2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO03535.1 - 7.1e-06 25.4 0.2 3.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain NMU PF02070.10 EDO03535.1 - 0.038 13.5 0.1 0.28 10.7 0.1 2.6 1 0 0 1 1 1 0 Neuromedin U Isochorismatase PF00857.15 EDO03536.1 - 4e-19 69.1 0.0 9.8e-19 67.9 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family PRC PF05239.11 EDO03536.1 - 0.051 13.4 0.7 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 PRC-barrel domain HMG-CoA_red PF00368.13 EDO03537.1 - 8.9e-158 524.8 3.0 1.2e-157 524.4 2.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EDO03537.1 - 1.1e-49 168.0 2.0 2e-49 167.1 1.1 1.7 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EDO03537.1 - 1.2e-12 47.5 8.3 5.6e-12 45.3 5.8 2.1 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EDO03537.1 - 3e-07 28.7 5.6 3e-07 28.7 3.9 1.4 2 0 0 2 2 2 1 Patched family DUF4533 PF15047.1 EDO03537.1 - 0.093 12.1 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF2304 PF10066.4 EDO03537.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Lig_chan PF00060.21 EDO03537.1 - 0.56 9.9 3.4 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel Atg14 PF10186.4 EDO03538.1 - 1.2e-25 90.0 1.8 3.7e-25 88.5 1.3 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 EDO03538.1 - 0.25 11.6 5.2 0.58 10.5 0.7 2.5 2 0 0 2 2 2 0 Snapin/Pallidin FliT PF05400.8 EDO03538.1 - 0.3 11.5 4.6 0.081 13.3 0.5 2.0 2 0 0 2 2 2 0 Flagellar protein FliT Fig1 PF12351.3 EDO03539.1 - 8.7e-33 113.7 1.1 1.2e-32 113.3 0.8 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EDO03539.1 - 7.1e-05 22.4 2.4 9e-05 22.1 1.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4225 PF13988.1 EDO03539.1 - 0.01 15.3 0.2 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF2254 PF10011.4 EDO03540.1 - 0.01 14.3 0.4 0.015 13.8 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) XFP_N PF09364.5 EDO03541.1 - 1.5e-180 599.7 0.0 2e-180 599.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EDO03541.1 - 1.6e-85 285.6 0.0 2.5e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EDO03541.1 - 1.1e-80 269.4 0.0 2.6e-80 268.2 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Sugar_tr PF00083.19 EDO03542.1 - 3.8e-111 371.8 20.8 4.4e-111 371.6 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO03542.1 - 5.9e-15 54.8 39.5 6e-15 54.8 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADK PF00406.17 EDO03543.1 - 1.6e-36 125.4 0.0 1.2e-19 70.7 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EDO03543.1 - 9.3e-12 44.4 0.0 1.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EDO03543.1 - 9.8e-06 26.3 0.0 2.5e-05 25.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO03543.1 - 1.1e-05 25.7 0.0 0.0001 22.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO03543.1 - 0.00025 20.9 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO03543.1 - 0.046 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EDO03543.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EDO03543.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EDO03543.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_S8 PF00082.17 EDO03546.1 - 4.2e-53 180.3 2.4 4.2e-53 180.3 1.7 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EDO03546.1 - 1.8e-26 91.7 1.0 5.5e-26 90.1 0.7 1.9 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF3156 PF11354.3 EDO03546.1 - 0.15 11.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) PX PF00787.19 EDO03547.1 - 2e-19 69.4 0.3 5.6e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EDO03547.1 - 1.6e-09 37.3 5.8 5e-05 22.6 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EDO03547.1 - 6.3e-08 32.3 0.2 1e-07 31.6 0.1 1.4 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 EDO03547.1 - 0.034 13.7 5.1 0.098 12.2 0.2 2.2 2 0 0 2 2 2 0 IncA protein DUF4404 PF14357.1 EDO03547.1 - 0.075 13.4 3.2 3.8 8.0 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Occludin_ELL PF07303.8 EDO03547.1 - 2.4 8.9 5.3 14 6.5 0.0 3.5 4 1 0 4 4 4 0 Occludin homology domain LETM1 PF07766.8 EDO03548.1 - 2e-92 309.0 1.9 1.2e-91 306.4 1.3 2.0 1 1 0 1 1 1 1 LETM1-like protein XLF PF09302.6 EDO03550.1 - 5.5e-39 133.6 0.4 9.9e-39 132.8 0.3 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) cwf21 PF08312.7 EDO03550.1 - 9.9 6.1 10.7 1.2 9.0 2.9 2.6 2 0 0 2 2 2 0 cwf21 domain Fig1 PF12351.3 EDO03551.1 - 3.3e-06 27.1 0.8 6.5e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 zf-C4H2 PF10146.4 EDO03551.1 - 0.066 13.2 7.5 0.17 11.8 5.2 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.14 EDO03551.1 - 1.2 6.9 7.6 1.8 6.3 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EDO03551.1 - 2 8.2 8.0 0.1 12.3 1.8 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.7 EDO03551.1 - 4.8 6.1 14.0 7.8 5.4 9.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 EDO03553.1 - 3.4e-17 61.5 14.4 4.8e-09 35.7 0.5 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat zf-rbx1 PF12678.2 EDO03553.1 - 0.0074 16.3 5.5 0.018 15.1 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 EDO03553.1 - 0.21 11.3 12.7 0.94 9.2 2.1 3.1 2 1 1 3 3 3 0 PHD-finger zf-RING_2 PF13639.1 EDO03553.1 - 3.4 7.5 10.5 0.21 11.4 2.2 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 EDO03553.1 - 7.1 6.3 8.1 6.3 6.5 1.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldedh PF00171.17 EDO03554.1 - 1.7e-123 412.3 0.0 2.1e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDO03554.1 - 2.1e-05 23.4 0.0 3.8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.13 EDO03556.1 - 1.4e-17 63.8 0.5 1.4e-17 63.8 0.4 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3499 PF12005.3 EDO03556.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DUF2424 PF10340.4 EDO03559.1 - 1.4e-06 27.2 0.0 1.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDO03559.1 - 5.5e-06 26.2 0.0 8.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDO03559.1 - 1.5e-05 24.6 0.0 3.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO03559.1 - 2.4e-05 24.3 0.0 3.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDO03559.1 - 0.0044 15.7 0.0 2 7.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family DUF1749 PF08538.5 EDO03559.1 - 0.0085 15.0 0.1 0.031 13.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1749) KTI12 PF08433.5 EDO03560.1 - 2.7e-74 249.7 0.0 3.7e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDO03560.1 - 2.6e-05 24.1 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO03560.1 - 0.0022 18.7 0.0 0.0054 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF1792 PF08759.6 EDO03560.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) AAA_18 PF13238.1 EDO03560.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDO03560.1 - 0.042 12.9 0.1 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EDO03560.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EDO03563.1 - 0.00067 19.8 4.1 0.15 12.4 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger MFS_1 PF07690.11 EDO03564.1 - 1.8e-18 66.4 62.7 1.4e-10 40.4 21.8 3.1 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.8 EDO03564.1 - 2e-10 39.5 24.0 2e-10 39.5 16.7 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_2 PF02230.11 EDO03565.1 - 9.7e-25 87.2 0.0 5.9e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDO03565.1 - 6.3e-06 26.2 0.0 9.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO03565.1 - 0.00013 21.2 0.0 0.036 13.2 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDO03565.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO03565.1 - 0.11 11.9 0.0 0.98 8.9 0.0 2.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Sec10 PF07393.6 EDO03569.1 - 1.5e-166 555.6 0.0 1.8e-166 555.3 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EDO03569.1 - 2.1e-06 27.3 0.1 1.8e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDO03569.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 EDO03570.1 - 1.9e-64 217.3 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO03570.1 - 2.6e-33 115.1 0.0 3.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO03570.1 - 0.00054 19.0 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO03570.1 - 0.14 11.8 0.2 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2810 PF10928.3 EDO03571.1 - 0.051 13.3 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) FAD_binding_3 PF01494.14 EDO03573.1 - 1.8e-07 30.5 0.5 0.00014 21.0 0.3 2.4 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDO03573.1 - 3.6e-07 30.1 0.9 7.6e-07 29.0 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO03573.1 - 1.1e-06 27.7 0.8 2.6e-06 26.6 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO03573.1 - 5e-05 22.3 1.0 7.4e-05 21.7 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO03573.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO03573.1 - 0.00024 21.4 0.7 0.00084 19.6 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDO03573.1 - 0.00038 19.8 0.1 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EDO03573.1 - 0.00075 18.0 0.8 0.0016 16.9 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EDO03573.1 - 0.0013 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EDO03573.1 - 0.0037 16.9 0.1 0.0054 16.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EDO03573.1 - 0.0037 16.1 0.4 0.005 15.7 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EDO03573.1 - 0.0037 16.3 0.5 0.0061 15.6 0.3 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EDO03573.1 - 0.007 16.1 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EDO03573.1 - 0.013 14.6 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EDO03573.1 - 0.013 14.8 0.4 0.025 14.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EDO03573.1 - 0.031 13.1 0.1 0.051 12.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 EDO03573.1 - 0.052 13.5 0.8 0.091 12.7 0.6 1.4 1 0 0 1 1 1 0 NADH(P)-binding Rossmann-like PF10727.4 EDO03573.1 - 0.052 13.2 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.10 EDO03573.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_oxidored PF12831.2 EDO03573.1 - 0.071 12.1 1.5 0.095 11.7 1.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDO03573.1 - 0.098 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EDO03573.1 - 0.15 11.5 0.2 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EDO03573.1 - 0.18 10.3 0.7 0.25 9.9 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase IlvN PF07991.7 EDO03573.1 - 0.2 11.0 0.7 0.44 9.8 0.5 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UbiA PF01040.13 EDO03574.1 - 1e-29 103.5 17.2 1.2e-29 103.2 11.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family BTP PF05232.7 EDO03574.1 - 1.1 9.0 6.6 8.8 6.1 0.1 3.5 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family DPM2 PF07297.7 EDO03574.1 - 8.5 6.7 10.0 0.84 9.9 3.1 2.4 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Methyltransf_2 PF00891.13 EDO03575.1 - 4.3e-20 71.9 0.0 6.9e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EDO03575.1 - 0.009 15.8 3.9 0.061 13.1 0.1 2.9 3 0 0 3 3 3 1 Dimerisation domain MarR_2 PF12802.2 EDO03575.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 MarR family Y_phosphatase3 PF13350.1 EDO03576.1 - 7.3e-14 52.3 0.0 4.2e-13 49.8 0.0 2.1 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EDO03576.1 - 2.6e-06 27.4 0.0 4.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EDO03576.1 - 2.5e-05 23.6 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EDO03576.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3812 PF12757.2 EDO03577.1 - 3e-39 133.8 9.6 3e-39 133.8 6.7 4.0 2 2 2 4 4 4 1 Protein of unknown function (DUF3812) TauD PF02668.11 EDO03579.1 - 6.2e-54 183.3 0.1 8.1e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ABC_membrane PF00664.18 EDO03580.1 - 1.3e-07 31.3 7.1 0.00014 21.3 0.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO03581.1 - 1.2e-27 96.8 0.0 4e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDO03581.1 - 7.2e-13 48.5 8.6 1.1e-12 47.9 6.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDO03581.1 - 0.00073 18.8 0.9 0.028 13.6 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EDO03581.1 - 0.015 15.1 0.9 0.028 14.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_21 PF13304.1 EDO03581.1 - 0.022 14.7 1.3 0.45 10.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EDO03581.1 - 0.025 14.5 0.2 0.067 13.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO03581.1 - 0.095 12.8 0.4 0.97 9.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EDO03581.1 - 0.16 12.4 0.4 0.41 11.1 0.3 1.7 1 0 0 1 1 1 0 Miro-like protein ABM PF03992.11 EDO03582.1 - 0.00063 19.7 0.6 0.28 11.2 0.2 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Acetyltransf_3 PF13302.1 EDO03583.1 - 2.5e-19 69.8 0.0 3.1e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO03583.1 - 0.013 15.5 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EDO03583.1 - 0.026 14.3 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_11 PF08241.7 EDO03584.1 - 2.4e-09 37.5 0.0 6.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO03584.1 - 6.3e-09 35.7 0.0 9.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03584.1 - 6e-08 33.0 0.0 1.9e-07 31.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03584.1 - 0.00027 20.5 0.0 0.00069 19.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03584.1 - 0.0032 17.7 0.0 0.0098 16.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO03584.1 - 0.0048 16.0 0.0 0.02 14.0 0.0 2.0 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDO03584.1 - 0.076 13.5 0.1 0.46 11.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Adaptin_N PF01602.15 EDO03585.1 - 9.8e-114 380.5 5.3 1.3e-113 380.1 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EDO03585.1 - 2.2e-36 124.2 0.0 4.7e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EDO03585.1 - 3.6e-21 75.6 0.0 6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain DnaJ PF00226.26 EDO03589.1 - 8.2e-21 73.5 1.3 8.2e-21 73.5 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3573 PF12097.3 EDO03589.1 - 0.19 10.2 2.6 0.27 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Androgen_recep PF02166.11 EDO03589.1 - 0.54 9.0 6.7 0.83 8.4 4.6 1.3 1 0 0 1 1 1 0 Androgen receptor Lge1 PF11488.3 EDO03589.1 - 9.2 6.5 12.3 0.12 12.5 2.2 2.6 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 bZIP_1 PF00170.16 EDO03594.1 - 0.0058 16.5 3.9 0.016 15.1 2.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO03594.1 - 0.012 15.4 8.6 0.022 14.5 6.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper IGR PF09597.5 EDO03596.1 - 4.4e-23 80.9 0.1 6.9e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif SNF2_N PF00176.18 EDO03597.1 - 1.3e-37 129.2 0.0 5.3e-32 110.8 0.1 2.5 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO03597.1 - 0.0022 17.8 0.0 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PALP PF00291.20 EDO03598.1 - 1.3e-66 224.9 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EDO03598.1 - 0.027 14.7 0.0 13 6.1 0.0 2.5 2 1 0 2 2 2 0 Rhodanese-like domain PPTA PF01239.17 EDO03599.1 - 6.2e-40 132.9 16.1 4.6e-09 35.2 1.0 6.1 6 1 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.1 EDO03599.1 - 0.0093 15.6 5.0 0.017 14.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4219 PF13961.1 EDO03599.1 - 4.7 6.7 8.1 14 5.2 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) GHMP_kinases_N PF00288.21 EDO03600.1 - 6.2e-20 71.0 0.0 1.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDO03600.1 - 1.8e-09 37.6 0.0 4.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EDO03600.1 - 0.014 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature RIB43A PF05914.7 EDO03602.1 - 0.054 12.1 0.2 0.056 12.0 0.2 1.0 1 0 0 1 1 1 0 RIB43A zf-H2C2_2 PF13465.1 EDO03607.1 - 4.1e-21 74.1 25.2 5.1e-08 32.8 0.4 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EDO03607.1 - 5e-18 64.2 37.4 2.4e-05 24.3 1.3 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO03607.1 - 2e-09 37.1 31.6 0.00078 19.6 1.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO03607.1 - 0.00072 19.6 6.1 5 7.3 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EDO03607.1 - 0.0031 17.8 14.1 0.021 15.2 1.7 3.6 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2HC_2 PF13913.1 EDO03607.1 - 0.56 9.9 5.2 29 4.4 0.1 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type CHORD PF04968.7 EDO03607.1 - 4 7.7 15.3 3.8 7.8 0.1 4.3 1 1 3 4 4 4 0 CHORD DUF4216 PF13952.1 EDO03608.1 - 0.084 12.3 0.2 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4216) Peptidase_M41 PF01434.13 EDO03609.1 - 6e-69 231.7 0.3 9.9e-69 231.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO03609.1 - 6.7e-42 142.8 0.0 1.6e-41 141.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO03609.1 - 7.9e-06 25.9 0.2 0.00024 21.1 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO03609.1 - 1.5e-05 25.1 0.2 0.0088 16.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO03609.1 - 1.9e-05 24.4 0.0 6.7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDO03609.1 - 3.4e-05 22.7 0.0 6.3e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EDO03609.1 - 5.3e-05 24.0 0.0 0.00014 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO03609.1 - 6e-05 22.5 1.1 0.038 13.4 0.2 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EDO03609.1 - 0.00032 19.8 0.0 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDO03609.1 - 0.00041 20.2 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO03609.1 - 0.002 17.8 0.6 0.0056 16.3 0.4 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EDO03609.1 - 0.0022 17.1 1.4 0.032 13.3 0.3 2.4 1 1 1 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EDO03609.1 - 0.0024 17.2 0.1 0.0057 16.0 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EDO03609.1 - 0.0052 15.7 0.2 0.051 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EDO03609.1 - 0.017 14.3 0.2 0.038 13.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDO03609.1 - 0.018 14.9 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.9 EDO03609.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EDO03609.1 - 0.032 14.1 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SpoU_sub_bind PF08032.7 EDO03609.1 - 0.037 14.1 0.3 11 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding DUF2973 PF11189.3 EDO03609.1 - 0.042 13.6 0.1 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) NACHT PF05729.7 EDO03609.1 - 0.084 12.5 0.3 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EDO03609.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO03609.1 - 0.12 11.6 0.4 0.28 10.3 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Nitroreductase PF00881.19 EDO03612.1 - 4e-21 75.5 0.0 5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Peptidase_M48 PF01435.13 EDO03613.1 - 1.2e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EDO03613.1 - 0.00019 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 Ribosomal_L34 PF00468.12 EDO03615.1 - 2.1e-14 52.8 10.4 3.4e-14 52.2 7.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DUF3408 PF11888.3 EDO03617.1 - 0.15 11.9 1.3 0.19 11.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) ExbD PF02472.11 EDO03619.1 - 0.11 12.5 0.3 0.14 12.1 0.2 1.2 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR 7TM_GPCR_Srw PF10324.4 EDO03619.1 - 0.11 11.6 0.2 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw p450 PF00067.17 EDO03620.1 - 3.8e-47 160.8 0.0 5.1e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_assoc PF14363.1 EDO03620.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Prenyltransf PF01255.14 EDO03621.1 - 3.8e-86 287.8 0.0 5.2e-86 287.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 EDO03622.1 - 8.8e-10 38.1 8.0 1.4e-09 37.4 5.6 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EDO03622.1 - 2.9e-09 37.1 0.0 3.6e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding vATP-synt_E PF01991.13 EDO03622.1 - 0.17 11.1 0.1 0.63 9.2 0.0 1.9 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit LRR_6 PF13516.1 EDO03624.1 - 0.00067 19.4 0.4 2 8.7 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EDO03624.1 - 0.0012 18.4 0.5 0.59 9.8 0.0 3.8 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EDO03624.1 - 1.8 9.0 5.8 43 4.9 0.0 5.3 7 0 0 7 7 7 0 Leucine rich repeat Uds1 PF15456.1 EDO03625.1 - 1.4e-43 147.8 5.0 1.4e-43 147.8 3.5 7.9 5 2 4 9 9 9 1 Up-regulated During Septation Spc7 PF08317.6 EDO03625.1 - 0.00031 19.5 8.8 0.00031 19.5 6.1 5.3 4 1 1 5 5 5 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EDO03625.1 - 3.6 6.6 19.9 0.026 13.6 4.8 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DNA_pol_E_B PF04042.11 EDO03626.1 - 1e-37 129.4 0.0 1.5e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B AA_permease PF00324.16 EDO03627.1 - 2.9e-56 190.8 35.5 4.5e-56 190.1 24.6 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO03627.1 - 1.2e-15 57.0 39.7 1.9e-15 56.3 27.5 1.2 1 0 0 1 1 1 1 Amino acid permease DALR_1 PF05746.10 EDO03627.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 DALR anticodon binding domain Aa_trans PF01490.13 EDO03629.1 - 2.7e-82 276.4 32.3 3.3e-82 276.1 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fanconi_A PF03511.9 EDO03629.1 - 0.035 13.8 0.3 0.095 12.4 0.2 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF3716 PF12511.3 EDO03631.1 - 2.3e-17 62.3 4.1 3.3e-17 61.8 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Herpes_UL25 PF01499.11 EDO03631.1 - 8.3 4.5 5.4 11 4.1 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family NMO PF03060.10 EDO03632.1 - 5.1e-38 131.0 0.1 1.2e-26 93.6 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EDO03632.1 - 3.6e-07 29.3 0.0 0.0092 14.8 0.4 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDO03632.1 - 0.00028 19.8 0.2 0.00038 19.3 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EDO03632.1 - 0.016 14.1 0.1 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF561 PF04481.7 EDO03632.1 - 0.073 12.0 0.7 0.16 10.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) RNA_pol_L_2 PF13656.1 EDO03633.1 - 9.1e-24 82.6 0.0 1.1e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDO03633.1 - 5.1e-13 47.9 0.0 7e-13 47.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.13 EDO03633.1 - 0.048 12.6 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EDO03637.1 - 9.4e-24 83.9 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO03637.1 - 3e-05 23.2 0.0 0.00031 19.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO03637.1 - 0.055 13.2 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SnoaL_4 PF13577.1 EDO03638.1 - 9.2e-12 44.9 0.1 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.1 EDO03642.1 - 3.5e-17 62.9 0.1 4.1e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO03642.1 - 2.6e-07 30.7 0.1 7.5e-07 29.2 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase Kp4 PF09044.5 EDO03642.1 - 0.028 14.2 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Kp4 SRF-TF PF00319.13 EDO03643.1 - 3.1e-24 83.9 0.2 5e-24 83.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NADH_4Fe-4S PF10589.4 EDO03644.1 - 0.073 12.2 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF3591 PF12157.3 EDO03647.1 - 4.7e-188 625.2 0.0 7.2e-188 624.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 EDO03647.1 - 0.0063 16.3 1.0 0.013 15.4 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EDO03647.1 - 0.015 14.9 1.0 0.039 13.6 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Ala_racemase_N PF01168.15 EDO03648.1 - 1.5e-12 47.5 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 EDO03648.1 - 1.2e-05 25.3 0.0 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Actin PF00022.14 EDO03649.1 - 2.9e-134 447.4 0.0 3.2e-134 447.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO03649.1 - 3.6e-08 32.3 0.0 0.1 11.1 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein Pkinase PF00069.20 EDO03650.1 - 6.7e-19 68.0 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 EDO03650.1 - 1.7e-17 62.6 6.3 0.00073 19.1 1.1 5.2 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.12 EDO03650.1 - 5.2e-17 61.7 0.0 5.6e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.1 EDO03650.1 - 7.7e-17 60.8 10.0 3.2e-09 36.3 1.0 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EDO03650.1 - 1.4e-11 42.7 5.7 0.051 13.6 0.2 7.3 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EDO03650.1 - 4.9e-07 28.8 9.8 1.8 9.1 0.2 7.1 8 0 0 8 8 7 2 Leucine rich repeat Kdo PF06293.9 EDO03650.1 - 7e-06 25.2 0.1 1.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO03650.1 - 0.0045 16.0 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO03650.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDO03650.1 - 0.0089 15.3 0.1 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family LRR_6 PF13516.1 EDO03650.1 - 0.13 12.4 9.5 2.5 8.4 0.1 5.7 6 2 1 7 7 6 0 Leucine Rich repeat ADH_zinc_N PF00107.21 EDO03651.1 - 1.1e-07 31.4 0.3 1.1e-07 31.4 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO03651.1 - 2.2e-06 27.3 0.0 1.2e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EDO03652.1 - 7.3e-11 42.2 0.1 2.4e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDO03652.1 - 0.00025 20.7 0.0 0.00095 18.8 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDO03652.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Thioredoxin_2 PF13098.1 EDO03652.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4448 PF14610.1 EDO03654.1 - 9.2e-47 158.9 0.0 1.3e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2404 PF10296.4 EDO03658.1 - 0.0046 17.0 0.0 0.07 13.2 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) S-antigen PF05756.6 EDO03658.1 - 0.34 10.9 3.0 0.63 10.0 2.1 1.4 1 0 0 1 1 1 0 S-antigen protein VPS28 PF03997.7 EDO03659.1 - 4.4e-52 176.4 0.1 5e-52 176.2 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EDO03659.1 - 0.0032 17.2 1.0 2.1 8.2 0.1 2.2 2 0 0 2 2 2 2 Gas vesicle protein G Noc2 PF03715.8 EDO03660.1 - 1.2e-122 408.4 2.2 2.8e-122 407.2 0.0 2.5 3 0 0 3 3 3 1 Noc2p family DUF3419 PF11899.3 EDO03661.1 - 8.9e-97 324.1 0.0 1.4e-96 323.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EDO03661.1 - 3e-12 46.5 0.0 1.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO03661.1 - 3.9e-10 40.3 0.0 1.9e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03661.1 - 3.6e-09 37.0 0.0 1.2e-08 35.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03661.1 - 4.5e-09 36.0 0.0 3.1e-08 33.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO03661.1 - 1.2e-07 31.0 0.0 9.2e-05 21.6 0.0 2.4 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EDO03661.1 - 8.4e-06 26.1 0.0 0.0022 18.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO03661.1 - 1.1e-05 25.3 0.0 0.00011 22.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03661.1 - 8.3e-05 22.8 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO03661.1 - 0.00045 19.8 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EDO03661.1 - 0.0045 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EDO03661.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EDO03661.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF3359 PF11839.3 EDO03662.1 - 0.065 13.5 1.2 0.14 12.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) DUF883 PF05957.8 EDO03662.1 - 0.47 10.8 4.2 5.2 7.5 0.3 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DPBB_1 PF03330.13 EDO03663.1 - 4.4e-08 33.0 0.1 7.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDO03663.1 - 0.00046 19.8 0.4 0.00066 19.3 0.3 1.2 1 0 0 1 1 1 1 Barwin family PI-PLC-X PF00388.14 EDO03664.1 - 2.2e-07 30.3 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Microtub_assoc PF07989.6 EDO03665.1 - 0.0037 17.0 6.4 0.0037 17.0 4.4 2.2 2 0 0 2 2 2 1 Microtubule associated AAA_23 PF13476.1 EDO03665.1 - 3 8.1 11.6 0.048 13.9 0.8 2.8 4 0 0 4 4 4 0 AAA domain DUF1992 PF09350.5 EDO03666.1 - 6.7e-25 86.7 2.1 7.5e-24 83.3 0.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.5 EDO03666.1 - 0.0093 15.5 0.2 0.042 13.4 0.1 2.1 1 0 0 1 1 1 1 RPAP1-like, N-terminal Mito_fiss_reg PF05308.6 EDO03667.1 - 0.077 12.3 3.3 0.11 11.8 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SAPS PF04499.10 EDO03668.1 - 5.6e-202 671.5 0.2 2.5e-201 669.4 0.0 2.0 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Snf7 PF03357.16 EDO03669.1 - 1.1e-43 148.5 9.4 1.3e-43 148.3 6.5 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EDO03669.1 - 0.014 14.8 9.8 0.034 13.5 5.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.15 EDO03669.1 - 0.048 13.4 11.6 0.073 12.8 0.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit DUF1569 PF07606.6 EDO03669.1 - 0.069 13.0 2.0 0.065 13.1 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) NPV_P10 PF05531.7 EDO03669.1 - 0.078 13.2 6.3 2.3 8.5 0.0 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Alpha-2-MRAP_C PF06401.6 EDO03669.1 - 0.13 12.1 2.8 0.084 12.7 0.4 1.7 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain BLOC1_2 PF10046.4 EDO03669.1 - 0.17 12.0 7.9 1.4 9.0 2.8 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.9 EDO03669.1 - 0.28 11.0 12.5 0.035 14.0 3.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.8 EDO03669.1 - 0.29 11.0 11.3 0.091 12.6 5.2 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 EDO03669.1 - 0.3 10.2 6.2 1 8.4 0.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EDO03669.1 - 0.6 10.0 6.3 15 5.5 1.4 3.3 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 EDO03669.1 - 0.63 8.3 8.7 0.25 9.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EDO03669.1 - 0.66 10.4 4.2 2.6 8.5 0.0 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EDO03669.1 - 1.3 8.6 10.5 1.4e+02 1.9 7.3 2.5 1 1 0 1 1 1 0 IncA protein COG2 PF06148.6 EDO03669.1 - 1.4 8.7 8.7 53 3.6 5.5 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Zn_clus PF00172.13 EDO03670.1 - 1.9e-09 37.2 10.2 3.4e-09 36.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDO03670.1 - 4.8e-07 28.7 0.3 6.9e-07 28.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLPTM1 PF05602.7 EDO03673.1 - 0.005 15.6 0.9 0.007 15.1 0.6 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Apq12 PF12716.2 EDO03673.1 - 0.21 11.3 1.5 0.33 10.6 1.0 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Pkinase PF00069.20 EDO03676.1 - 1.3e-20 73.6 0.0 1.2e-19 70.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO03676.1 - 5.8e-07 28.8 0.0 0.0018 17.3 0.0 3.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO03676.1 - 0.024 13.6 0.0 0.32 9.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Chitin_synth_2 PF03142.10 EDO03677.1 - 1.8e-11 43.1 4.9 4.7e-10 38.4 3.4 2.5 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.1 EDO03677.1 - 4e-07 29.5 0.1 9.6e-07 28.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EDO03677.1 - 1.4e-06 28.1 3.7 2.8e-06 27.1 2.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO03677.1 - 3.2e-06 27.1 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDO03677.1 - 0.00066 19.4 0.0 0.0016 18.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Fringe PF02434.11 EDO03680.1 - 2.6e-05 23.5 2.5 0.0013 18.0 1.2 3.1 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.1 EDO03680.1 - 0.011 15.4 4.6 0.027 14.1 3.2 1.6 1 0 0 1 1 1 0 PAN domain Nebulin PF00880.13 EDO03680.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Nebulin repeat Auxin_BP PF02041.11 EDO03681.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Thg1 PF04446.7 EDO03684.1 - 3.5e-47 159.4 0.1 4.6e-47 159.0 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EDO03684.1 - 3.1e-42 143.0 1.1 4.2e-42 142.6 0.7 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain AlaDh_PNT_N PF05222.10 EDO03685.1 - 3.5e-28 98.2 0.0 5.1e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EDO03685.1 - 8.1e-18 64.5 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2564 PF10819.3 EDO03686.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) WBP-1 PF11669.3 EDO03687.1 - 0.033 14.2 0.2 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF1049 PF06305.6 EDO03687.1 - 2.7 7.5 6.2 16 5.0 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) QCR10 PF09796.4 EDO03689.1 - 0.0068 16.0 0.6 0.019 14.5 0.4 1.8 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MARVEL PF01284.18 EDO03689.1 - 0.017 14.9 14.5 0.15 11.9 9.9 2.1 1 1 0 1 1 1 0 Membrane-associating domain EmrE PF13536.1 EDO03689.1 - 0.77 9.9 10.4 0.12 12.6 3.7 1.9 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Peptidase_M16 PF00675.15 EDO03691.1 - 1.3e-56 190.5 0.2 4.4e-56 188.7 0.1 1.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO03691.1 - 2.2e-38 131.7 0.1 7e-38 130.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 EDO03692.1 - 2.2e-52 176.2 0.0 2.8e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 CybS LNS2 PF08235.8 EDO03694.1 - 1.8e-70 235.5 0.0 3.2e-70 234.7 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EDO03694.1 - 5.5e-42 141.9 0.3 1.3e-39 134.2 0.0 3.1 3 0 0 3 3 3 1 lipin, N-terminal conserved region AF1Q PF15017.1 EDO03694.1 - 0.00047 20.0 2.9 0.00047 20.0 2.0 2.5 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 EDO03694.1 - 0.014 14.7 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EDO03696.1 - 2e-07 31.0 0.0 5.8e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain HVSL PF09749.4 EDO03698.1 - 5.1e-91 303.9 0.0 8.3e-91 303.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3472 PF11958.3 EDO03698.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Pal1 PF08316.6 EDO03699.1 - 3.2e-09 37.3 1.3 1.1e-08 35.6 0.0 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein HATPase_c PF02518.21 EDO03700.1 - 7.5e-22 77.1 0.0 1.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDO03700.1 - 7.9e-20 70.9 0.1 1.5e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EDO03700.1 - 3.6e-12 46.5 0.0 1.2e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EDO03700.1 - 9e-11 41.5 0.1 5.5e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold HisKA PF00512.20 EDO03700.1 - 8.5e-08 32.0 0.6 6.5e-07 29.2 0.4 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EDO03700.1 - 7.6e-07 29.1 0.0 0.00034 20.6 0.0 3.1 3 0 0 3 3 3 1 PAS fold GAF_3 PF13492.1 EDO03700.1 - 0.0069 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_3 PF08447.6 EDO03700.1 - 0.0079 16.2 0.1 0.021 14.9 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EDO03700.1 - 0.035 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAF-AH_p_II PF03403.8 EDO03701.1 - 9e-52 175.6 0.0 1.2e-46 158.7 0.0 2.8 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EDO03701.1 - 9.8e-12 44.8 0.0 2.7e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO03701.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EDO03701.1 - 0.00024 20.0 0.0 0.0036 16.2 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDO03701.1 - 0.0024 16.7 0.0 0.0045 15.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.15 EDO03701.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4337 PF14235.1 EDO03702.1 - 8 6.2 5.7 24 4.7 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ABC_membrane PF00664.18 EDO03703.1 - 4.6e-75 252.5 31.8 7.6e-39 133.7 9.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO03703.1 - 2.4e-59 199.5 0.0 3.5e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO03703.1 - 1.3e-14 53.9 2.4 2.4e-06 26.9 0.2 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDO03703.1 - 7.3e-11 42.3 2.9 1.3e-06 28.5 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EDO03703.1 - 1.4e-09 38.4 0.3 0.16 11.9 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EDO03703.1 - 3.3e-08 32.9 0.3 0.012 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO03703.1 - 2.1e-07 31.1 0.2 0.032 14.3 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EDO03703.1 - 8.8e-07 29.7 0.0 0.028 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDO03703.1 - 9e-06 24.5 0.5 0.0049 15.4 0.0 3.2 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 EDO03703.1 - 4.1e-05 23.2 0.8 0.21 11.1 0.0 3.9 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EDO03703.1 - 8.7e-05 21.7 0.1 0.076 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDO03703.1 - 0.00013 21.4 0.0 0.36 10.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 EDO03703.1 - 0.00019 21.3 0.4 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EDO03703.1 - 0.00099 18.9 0.1 0.29 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO03703.1 - 0.0018 18.5 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EDO03703.1 - 0.002 18.0 2.3 2.5 8.0 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EDO03703.1 - 0.0048 16.0 0.0 0.87 8.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EDO03703.1 - 0.0072 16.0 1.8 2 8.2 0.0 3.4 3 0 0 3 3 2 1 Part of AAA domain DUF3987 PF13148.1 EDO03703.1 - 0.0082 14.7 0.0 1.4 7.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.18 EDO03703.1 - 0.0098 15.8 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.15 EDO03703.1 - 0.014 15.0 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.9 EDO03703.1 - 0.014 15.1 0.1 7.6 6.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EDO03703.1 - 0.019 15.3 0.0 6.2 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EDO03703.1 - 0.045 13.1 0.0 7.6 5.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EDO03703.1 - 0.051 13.0 4.2 1.3 8.3 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain AMP-binding PF00501.23 EDO03704.1 - 2.3e-221 734.5 0.0 6e-75 252.1 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EDO03704.1 - 4.1e-170 564.3 3.4 1.4e-38 132.5 0.0 5.3 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EDO03704.1 - 8.8e-41 138.0 8.6 1.1e-08 35.1 0.1 5.7 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDO03704.1 - 1.4e-12 48.3 0.5 0.00066 20.5 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EDO03704.1 - 0.0024 17.4 0.2 0.35 10.3 0.0 2.9 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain GH3 PF03321.8 EDO03704.1 - 0.0049 15.4 0.0 0.31 9.4 0.0 3.1 3 0 0 3 3 3 1 GH3 auxin-responsive promoter Catalase PF00199.14 EDO03705.1 - 1.8e-159 530.5 0.9 2.3e-159 530.1 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDO03705.1 - 1.5e-17 63.1 0.1 3.6e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive AKNA PF12443.3 EDO03706.1 - 2.5 8.1 6.2 2.1 8.4 0.5 3.0 3 0 0 3 3 3 0 AT-hook-containing transcription factor Methyltransf_28 PF02636.12 EDO03707.1 - 4.7e-40 137.5 0.0 6.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EDO03707.1 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PALP PF00291.20 EDO03708.1 - 3.6e-55 187.3 0.8 4.7e-55 186.9 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_S5_C PF03719.10 EDO03708.1 - 0.019 14.2 0.2 39 3.6 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain Rhomboid PF01694.17 EDO03709.1 - 1e-05 25.6 3.2 1.6e-05 24.9 2.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EDO03709.1 - 4.8e-05 23.6 0.4 0.0001 22.5 0.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 EDO03709.1 - 1 8.8 10.3 1.7 8.0 7.1 1.5 1 1 0 1 1 1 0 Der1-like family TEA PF01285.13 EDO03711.1 - 4.1e-24 85.5 0.5 2.5e-21 76.3 0.0 2.7 3 0 0 3 3 3 2 TEA/ATTS domain family RRM_1 PF00076.17 EDO03712.1 - 1.7e-77 255.0 1.4 1.5e-18 66.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO03712.1 - 6.3e-63 208.6 0.3 3.6e-14 52.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO03712.1 - 2e-33 114.0 0.0 7e-07 28.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO03712.1 - 6.8e-06 25.7 0.5 1.4 8.7 0.0 4.9 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 EDO03712.1 - 1.8e-05 24.4 0.0 0.19 11.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDO03712.1 - 0.0033 17.2 7.5 6.1 6.7 0.0 5.2 4 2 1 5 5 5 2 RNA binding motif CBP4 PF07960.6 EDO03712.1 - 0.039 13.5 0.4 0.039 13.5 0.3 2.9 1 1 1 2 2 2 0 CBP4 Dynein_light PF01221.13 EDO03713.1 - 1.8e-40 136.8 0.9 2e-40 136.6 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm6 PF14434.1 EDO03713.1 - 0.041 13.5 0.1 3.9 7.2 0.1 2.0 1 1 1 2 2 2 0 Immunity protein Imm6 EFhand_Ca_insen PF08726.5 EDO03713.1 - 0.085 12.8 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2051 PF09738.4 EDO03715.1 - 0.02 14.2 1.0 0.02 14.2 0.7 3.1 1 1 2 3 3 3 0 Double stranded RNA binding protein (DUF2051) DUF2237 PF09996.4 EDO03718.1 - 7e-25 86.7 0.5 1.4e-24 85.8 0.3 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Methyltrans_RNA PF04452.9 EDO03718.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Ribonucleas_3_3 PF14622.1 EDO03719.1 - 4.3e-07 29.9 0.0 6.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDO03719.1 - 0.042 14.2 0.0 0.064 13.7 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease III domain Ribonuc_L-PSP PF01042.16 EDO03721.1 - 2.8e-37 127.1 0.0 3.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1187 PF06688.6 EDO03721.1 - 0.042 13.9 0.1 0.078 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) Pkinase PF00069.20 EDO03722.1 - 3.7e-72 242.5 0.0 5.3e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO03722.1 - 8.1e-35 120.1 0.0 1.7e-34 119.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO03722.1 - 0.0056 15.6 0.3 0.5 9.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like DUF2413 PF10310.4 EDO03725.1 - 4.3e-156 520.1 0.0 4.9e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EDO03725.1 - 0.062 13.3 0.2 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Pex14_N PF04695.8 EDO03725.1 - 1.5 8.8 11.0 13 5.8 7.7 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 EDO03727.1 - 2.6e-35 121.7 22.3 3.3e-35 121.4 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO03727.1 - 3e-08 32.6 12.3 4e-08 32.2 8.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDO03727.1 - 0.0036 15.5 5.3 0.0046 15.2 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EDO03727.1 - 0.23 9.5 5.1 0.33 9.0 3.5 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector LicD PF04991.8 EDO03728.1 - 5.6e-34 118.0 3.6 5.6e-34 118.0 2.5 4.0 2 2 1 3 3 3 1 LicD family p450 PF00067.17 EDO03730.1 - 6.2e-78 262.3 0.0 7.4e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 EDO03731.1 - 2e-17 62.9 33.1 3.1e-17 62.2 22.9 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SepZ PF06066.6 EDO03731.1 - 3 7.9 8.5 6.6 6.8 1.2 3.3 4 0 0 4 4 4 0 SepZ ArsD PF06953.6 EDO03732.1 - 0.054 13.6 0.8 0.078 13.1 0.6 1.2 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD Dicty_CTDC PF00526.13 EDO03732.1 - 0.32 10.8 2.9 0.81 9.5 0.0 2.2 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat CinA PF02464.12 EDO03733.1 - 2.4e-34 118.0 0.1 2.7e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein GP4 PF03010.9 EDO03734.1 - 0.023 14.3 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 GP4 RecR PF02132.10 EDO03734.1 - 0.22 10.9 2.7 2.4 7.6 0.2 2.3 2 0 0 2 2 2 0 RecR protein zf-trcl PF13451.1 EDO03734.1 - 1.7 8.3 6.0 0.13 11.9 1.0 1.5 2 0 0 2 2 2 0 Probable zinc-binding domain SSF PF00474.12 EDO03735.1 - 2.9e-14 52.5 24.4 1.5e-10 40.3 10.8 2.3 1 1 1 2 2 2 2 Sodium:solute symporter family PAH PF02671.16 EDO03736.1 - 5.4e-40 134.7 1.2 5.7e-17 61.0 0.1 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EDO03736.1 - 4.5e-30 103.3 0.1 2.5e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor Fasciclin PF02469.17 EDO03737.1 - 0.0051 16.8 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain FAD_binding_2 PF00890.19 EDO03741.1 - 4.1e-84 282.8 0.7 5.1e-84 282.5 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EDO03741.1 - 6.2e-21 73.9 0.2 4e-19 68.1 0.0 2.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EDO03741.1 - 1.5e-14 53.7 0.8 4.4e-14 52.1 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EDO03741.1 - 3.5e-09 36.2 0.2 1.2e-08 34.5 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO03741.1 - 1.3e-08 34.6 1.7 1.3e-07 31.5 0.2 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO03741.1 - 7.1e-07 28.5 0.7 0.0025 16.9 0.1 3.2 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 EDO03741.1 - 2.6e-06 27.4 0.0 0.00013 21.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO03741.1 - 1.9e-05 23.3 2.7 0.0035 15.8 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 EDO03741.1 - 0.00038 19.4 1.9 0.073 11.9 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EDO03741.1 - 0.0021 17.1 1.1 0.0041 16.2 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDO03741.1 - 0.011 15.7 0.2 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDO03741.1 - 0.019 14.0 0.3 0.65 9.0 0.1 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EDO03741.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EDO03741.1 - 0.14 11.9 0.1 0.91 9.2 0.1 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO03741.1 - 0.52 10.7 4.0 2.3 8.6 1.2 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 EDO03742.1 - 7.4e-77 258.8 15.9 8.5e-77 258.6 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3810 PF12725.2 EDO03742.1 - 1.7 7.4 5.6 2.7 6.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF4234 PF14018.1 EDO03743.1 - 0.067 12.9 0.9 0.16 11.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) 7TM_GPCR_Str PF10326.4 EDO03743.1 - 0.58 9.2 6.8 0.096 11.7 2.1 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF2769 PF10967.3 EDO03744.1 - 0.19 12.0 0.7 0.39 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) PH_6 PF15406.1 EDO03746.1 - 5.9e-44 148.6 2.9 5.9e-44 148.6 2.0 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain GAGA_bind PF06217.7 EDO03746.1 - 5.6 6.8 23.2 0.48 10.3 7.8 2.7 2 0 0 2 2 2 0 GAGA binding protein-like family Cupin_5 PF06172.6 EDO03747.1 - 3.8e-39 133.7 0.1 4.3e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF221 PF02714.10 EDO03748.1 - 0.0026 16.6 6.4 0.0038 16.1 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 UT PF03253.9 EDO03748.1 - 0.0067 15.3 2.9 0.0092 14.9 2.0 1.1 1 0 0 1 1 1 1 Urea transporter Cupin_5 PF06172.6 EDO03749.1 - 1.1e-33 116.0 0.0 1.3e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) MFS_1 PF07690.11 EDO03750.1 - 4.8e-32 111.0 18.7 4.8e-32 111.0 13.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3112 PF11309.3 EDO03750.1 - 0.23 11.2 5.0 1.1 8.9 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) TauD PF02668.11 EDO03751.1 - 1.8e-51 175.2 0.1 2.2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4440 PF14534.1 EDO03753.1 - 2.1e-06 27.9 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) PAT1 PF09770.4 EDO03753.1 - 8.7 4.4 19.9 11 4.1 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_28 PF00295.12 EDO03754.1 - 3.6e-16 59.0 0.0 1.8e-10 40.2 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EDO03754.1 - 3.3 7.7 14.5 7.3 6.6 0.0 3.8 2 2 1 4 4 4 0 Pectate lyase superfamily protein adh_short PF00106.20 EDO03762.1 - 0.00062 19.7 0.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Sld5 PF05916.6 EDO03764.1 - 1.9e-15 57.0 0.0 2.5e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 EDO03765.1 - 3.1e-38 129.8 0.7 5.4e-38 129.0 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDO03765.1 - 1e-30 105.7 0.6 1.8e-30 105.0 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CGGC PF08821.6 EDO03769.1 - 0.085 12.9 0.8 0.22 11.5 0.2 1.9 2 0 0 2 2 2 0 CGGC domain adh_short PF00106.20 EDO03771.1 - 5.2e-20 72.0 0.0 8.9e-20 71.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO03771.1 - 3.4e-07 30.1 0.0 0.00035 20.2 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EDO03771.1 - 0.00015 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDO03771.1 - 0.11 11.9 0.0 8.3 5.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EDO03774.1 - 1e-08 34.8 7.8 1.8e-08 34.1 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO03774.1 - 0.003 16.4 0.1 0.037 12.9 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.9 EDO03776.1 - 3e-39 134.8 4.3 3.9e-39 134.4 2.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EDO03776.1 - 7.9e-05 22.4 5.1 0.00016 21.4 3.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4218 PF13960.1 EDO03779.1 - 0.14 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) tRNA-Thr_ED PF08915.6 EDO03780.1 - 0.072 13.0 0.2 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase RESP18 PF14948.1 EDO03781.1 - 0.02 14.9 0.2 0.021 14.8 0.2 1.1 1 0 0 1 1 1 0 RESP18 domain GMC_oxred_N PF00732.14 EDO03783.1 - 1.4e-22 80.2 0.0 2.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO03783.1 - 5.5e-22 78.6 0.8 1.2e-21 77.5 0.6 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDO03783.1 - 4.9e-06 25.6 0.0 8.4e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EDO03783.1 - 0.0001 21.5 0.1 0.00026 20.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EDO03783.1 - 0.00012 21.1 0.1 0.00032 19.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO03783.1 - 0.00098 19.1 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDO03783.1 - 0.0011 17.5 0.7 0.0015 17.0 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EDO03783.1 - 0.0012 18.7 0.1 0.0032 17.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO03783.1 - 0.0021 18.1 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO03783.1 - 0.0051 15.9 0.1 0.015 14.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EDO03783.1 - 0.011 14.7 0.1 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SnoaL_2 PF12680.2 EDO03784.1 - 1.9e-11 44.2 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EDO03784.1 - 6.9e-08 32.1 0.1 1.5e-07 31.0 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 EDO03784.1 - 0.00011 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EDO03784.1 - 0.00015 21.9 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.15 EDO03784.1 - 0.027 14.8 0.1 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain RICTOR_M PF14666.1 EDO03784.1 - 0.036 13.0 0.5 2.5 7.0 0.1 2.1 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain PhyH PF05721.8 EDO03785.1 - 1.3e-31 110.2 0.0 2.5e-31 109.3 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Tenui_NCP PF04876.7 EDO03785.1 - 0.056 12.9 0.3 0.45 10.0 0.1 2.3 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Nramp PF01566.13 EDO03786.1 - 4.8e-76 255.8 20.2 7.2e-76 255.2 14.0 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Na_Ca_ex PF01699.19 EDO03787.1 - 1.3e-25 89.6 30.6 3e-13 49.5 8.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UDG PF03167.14 EDO03788.1 - 8e-26 90.3 0.1 1.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mito_carr PF00153.22 EDO03789.1 - 1.4e-62 207.4 1.2 8.7e-21 73.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EDO03790.1 - 6.4e-13 48.2 0.0 1.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO03790.1 - 6.8e-06 25.6 0.0 2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EDO03790.1 - 0.12 12.0 0.3 0.3 10.8 0.2 1.8 1 1 0 1 1 1 0 F-box-like domain TPR_1 PF00515.23 EDO03790.1 - 0.18 11.5 0.2 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Formyl_trans_N PF00551.14 EDO03791.1 - 8.4e-37 126.4 0.1 1.1e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EDO03791.1 - 3.9e-10 39.0 0.0 1.2e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EDO03791.1 - 2.1e-07 30.5 0.0 6.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain FAD_binding_4 PF01565.18 EDO03792.1 - 9.6e-16 57.5 0.7 2e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain DDE_1 PF03184.14 EDO03793.1 - 2.7e-48 163.9 0.0 4.8e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03793.1 - 6.9e-08 32.1 0.6 4.6e-07 29.5 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO03793.1 - 7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO03793.1 - 0.012 15.5 7.6 0.023 14.5 5.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EDO03795.1 - 3.6e-07 29.7 0.0 7.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1708 PF08101.6 EDO03796.1 - 1.1e-165 551.5 0.0 1.5e-165 551.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) BCA_ABC_TP_C PF12399.3 EDO03796.1 - 0.89 9.3 4.3 4.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DUF3337 PF11816.3 EDO03797.1 - 0.0048 16.3 1.3 0.0065 15.9 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) DUF3338 PF11819.3 EDO03797.1 - 0.02 14.3 1.1 0.041 13.3 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) DUF2058 PF09831.4 EDO03797.1 - 1.3 8.8 10.5 1.9 8.3 7.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Kelch_5 PF13854.1 EDO03799.1 - 8.2e-18 63.9 10.8 1.5e-12 47.1 0.7 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 EDO03799.1 - 1.6e-12 47.0 9.9 0.00041 20.0 0.0 6.7 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO03799.1 - 2e-07 30.9 11.0 0.00036 20.6 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO03799.1 - 3.9e-06 26.7 10.9 0.2 11.8 0.2 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EDO03799.1 - 0.0055 16.4 4.5 7.6 6.4 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EDO03799.1 - 0.065 12.7 12.2 0.69 9.5 0.2 4.3 4 0 0 4 4 4 0 Kelch motif Ank_2 PF12796.2 EDO03800.1 - 5e-48 161.3 3.6 8.9e-14 51.5 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDO03800.1 - 2.1e-43 144.0 11.3 2.3e-06 27.1 0.0 8.9 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 EDO03800.1 - 3.1e-32 107.3 4.5 0.0027 17.8 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 EDO03800.1 - 1.6e-31 108.1 6.1 4e-06 27.1 0.1 6.9 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO03800.1 - 3.5e-27 93.7 9.2 7.3e-06 26.0 0.1 7.1 3 1 2 7 7 7 5 Ankyrin repeats (many copies) TPR_12 PF13424.1 EDO03801.1 - 3.2e-35 119.9 15.6 5.8e-14 51.7 0.6 5.2 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 EDO03801.1 - 2.5e-15 55.8 11.5 1.1e-05 25.1 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat NACHT PF05729.7 EDO03801.1 - 9.9e-08 31.8 0.0 2.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 EDO03801.1 - 2.7e-07 30.1 0.1 0.37 10.4 0.0 4.1 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.1 EDO03801.1 - 3.3e-07 30.7 2.3 0.26 12.0 0.1 4.4 3 2 1 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 EDO03801.1 - 6.5e-07 29.5 0.1 6.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.1 EDO03801.1 - 9.2e-06 25.0 7.5 0.043 13.6 0.0 5.4 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO03801.1 - 1.2e-05 24.8 3.0 4.2 7.5 0.2 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO03801.1 - 2.9e-05 23.4 0.4 0.99 9.1 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 EDO03801.1 - 9.1e-05 22.5 0.0 0.00039 20.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EDO03801.1 - 0.00032 19.8 0.1 0.28 10.1 0.2 2.3 1 1 1 2 2 2 2 KAP family P-loop domain TPR_14 PF13428.1 EDO03801.1 - 0.00081 19.8 3.5 30 5.6 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO03801.1 - 0.0022 17.6 0.1 3.2 7.7 0.0 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO03801.1 - 0.014 15.5 0.2 5.2 7.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ACT PF01842.20 EDO03801.1 - 0.02 14.3 0.1 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 ACT domain TPR_4 PF07721.9 EDO03801.1 - 0.02 15.2 9.5 2.7 8.6 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EDO03801.1 - 0.027 14.6 0.1 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDO03801.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPR_19 PF14559.1 EDO03801.1 - 0.057 13.7 0.1 9.7 6.6 0.0 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat AAA PF00004.24 EDO03801.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PPR PF01535.15 EDO03801.1 - 0.28 11.2 0.9 26 5.0 0.0 4.0 4 0 0 4 4 3 0 PPR repeat ENTH PF01417.15 EDO03802.1 - 1.2e-46 157.6 0.2 1.7e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 EDO03802.1 - 0.00011 20.6 7.5 0.00014 20.3 5.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 ANTH PF07651.11 EDO03802.1 - 0.00099 17.8 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.16 EDO03803.1 - 8.9e-41 139.6 0.4 1e-40 139.4 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.7 EDO03804.1 - 3.4e-90 302.5 0.0 4.3e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EDO03804.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal EndIII_4Fe-2S PF10576.4 EDO03804.1 - 0.62 10.3 3.3 1.2 9.4 2.3 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III ADH_zinc_N PF00107.21 EDO03806.1 - 2.2e-21 75.7 0.1 3.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO03806.1 - 2e-06 28.7 0.0 8.4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Mob_Pre PF01076.14 EDO03807.1 - 0.082 12.5 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme AAT PF03417.11 EDO03809.1 - 0.0088 15.5 0.4 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase HTH_psq PF05225.11 EDO03810.1 - 8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDO03810.1 - 3.3e-05 23.1 0.0 7.1e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease ATP_bind_4 PF01902.12 EDO03810.1 - 0.037 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 ATP-binding region PX PF00787.19 EDO03813.1 - 2.2e-20 72.5 0.0 3.4e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 PX domain Thioredoxin_4 PF13462.1 EDO03814.1 - 8.7e-10 38.8 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDO03814.1 - 0.061 13.5 0.0 0.3 11.3 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain SKG6 PF08693.5 EDO03816.1 - 1.1e-09 37.4 2.7 2.6e-09 36.2 1.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EDO03816.1 - 0.0002 21.0 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF2207 PF09972.4 EDO03816.1 - 0.14 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MatE PF01554.13 EDO03816.1 - 0.2 11.2 6.9 0.32 10.5 4.7 1.2 1 0 0 1 1 1 0 MatE Macoilin PF09726.4 EDO03816.1 - 1.3 7.2 4.5 1.6 6.8 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Cation_efflux PF01545.16 EDO03817.1 - 3.4e-73 246.1 6.6 1.3e-72 244.3 4.6 1.7 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.10 EDO03819.1 - 2.8e-16 59.4 0.8 2.8e-16 59.4 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Prominin PF05478.6 EDO03819.1 - 0.14 9.6 3.0 0.18 9.3 2.1 1.1 1 0 0 1 1 1 0 Prominin OAD_gamma PF04277.8 EDO03819.1 - 0.42 11.0 7.5 1 9.8 5.2 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_3 PF00933.16 EDO03822.1 - 1.5e-38 132.4 0.0 1.8e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDO03823.1 - 2.2e-70 236.7 0.0 8.6e-70 234.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDO03823.1 - 6.3e-24 83.7 0.0 1.5e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EDO03823.1 - 1.7e-10 40.7 0.0 3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain LIP PF03583.9 EDO03823.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase HATPase_c PF02518.21 EDO03824.1 - 9e-31 105.8 0.2 1.8e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDO03824.1 - 5.9e-21 74.2 0.1 1.5e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EDO03824.1 - 7.5e-20 71.0 0.0 2e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 EDO03824.1 - 1.1e-17 63.9 0.9 2.5e-17 62.7 0.6 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EDO03824.1 - 2.7e-13 50.1 0.0 6.3e-11 42.5 0.0 3.6 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EDO03824.1 - 5.9e-08 32.7 0.0 3.3e-05 23.8 0.0 3.5 3 1 0 3 3 3 1 PAS fold PAS PF00989.19 EDO03824.1 - 4.2e-07 29.7 0.1 0.015 15.0 0.0 4.5 4 0 0 4 4 4 2 PAS fold HATPase_c_3 PF13589.1 EDO03824.1 - 0.0073 15.9 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GRIP PF01465.15 EDO03824.1 - 0.14 11.7 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 GRIP domain Kelch_2 PF07646.10 EDO03825.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Kelch motif tRNA-synt_2 PF00152.15 EDO03830.1 - 1.4e-79 267.3 0.0 1.7e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EDO03830.1 - 3.3e-08 33.0 0.1 3.2e-06 26.5 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDO03830.1 - 0.026 14.1 0.0 0.32 10.5 0.0 2.2 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 EDO03831.1 - 1.9e-23 81.4 1.1 2.2e-23 81.2 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EDO03831.1 - 0.038 13.6 1.4 0.038 13.6 1.0 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Tropomyosin_1 PF12718.2 EDO03832.1 - 0.016 15.0 0.9 0.016 15.0 0.6 2.5 2 1 1 3 3 3 0 Tropomyosin like Spc7 PF08317.6 EDO03832.1 - 0.036 12.7 2.8 0.075 11.6 1.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PG_binding_1 PF01471.13 EDO03832.1 - 0.036 14.0 0.1 23 5.0 0.0 3.6 4 0 0 4 4 4 0 Putative peptidoglycan binding domain Syntaxin_2 PF14523.1 EDO03832.1 - 0.091 12.8 1.3 2 8.4 0.0 2.8 1 1 1 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.4 EDO03832.1 - 0.17 12.0 1.1 0.55 10.3 0.7 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.15 EDO03832.1 - 0.26 10.3 11.5 6.2 5.8 0.1 3.1 2 1 0 2 2 2 0 Tropomyosin Occludin_ELL PF07303.8 EDO03832.1 - 0.69 10.6 6.1 1.7 9.4 0.5 2.8 3 0 0 3 3 3 0 Occludin homology domain CLTH PF10607.4 EDO03833.1 - 7e-32 110.1 0.1 8.9e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EDO03833.1 - 2.4e-18 65.5 1.0 5.2e-18 64.4 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EDO03833.1 - 6.5e-05 22.2 0.0 9.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EDO03833.1 - 0.00053 19.7 0.5 0.00088 19.0 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO03833.1 - 0.0016 18.4 1.1 0.0028 17.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO03833.1 - 0.0022 17.6 0.3 0.0038 16.9 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO03833.1 - 0.01 15.4 0.6 0.019 14.6 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO03833.1 - 0.11 12.1 0.7 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO03833.1 - 0.16 11.8 0.9 0.31 10.9 0.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PPP4R2 PF09184.6 EDO03834.1 - 1.9e-08 34.2 0.0 1.9e-08 34.2 0.0 2.6 2 1 0 2 2 2 1 PPP4R2 PsiA PF06952.6 EDO03834.1 - 0.072 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 PsiA protein DJ-1_PfpI PF01965.19 EDO03837.1 - 1.5e-21 76.3 0.0 2.9e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EDO03837.1 - 7.1e-18 63.8 0.0 1.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EDO03837.1 - 0.065 12.4 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative amidotransferase Perilipin PF03036.11 EDO03838.1 - 0.0023 16.8 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Perilipin family Metallophos PF00149.23 EDO03841.1 - 1.5e-11 44.0 8.7 5.5e-11 42.2 3.8 2.6 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase DUF1399 PF07173.7 EDO03842.1 - 2.1e-19 70.1 0.3 2.3e-15 57.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) RVT_1 PF00078.22 EDO03843.1 - 1.1e-34 119.7 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO03843.1 - 1e-12 48.5 0.0 1.7e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDO03843.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like TetR PF13972.1 EDO03843.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor RNase_H PF00075.19 EDO03845.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 RNase H RVT_1 PF00078.22 EDO03846.1 - 1.9e-14 53.5 0.1 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDO03847.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDO03847.1 - 0.009 15.9 9.4 0.011 15.6 3.0 2.7 2 0 0 2 2 2 1 Zinc knuckle RNase_H PF00075.19 EDO03848.1 - 4.2e-10 40.0 0.0 5.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 RNase H DUF2562 PF10814.3 EDO03848.1 - 0.061 13.2 0.1 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) PEP_mutase PF13714.1 EDO03848.1 - 0.1 11.7 0.2 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase NmrA PF05368.8 EDO03850.1 - 6e-24 84.5 0.1 7.4e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDO03850.1 - 2e-12 47.5 0.1 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EDO03850.1 - 1.9e-06 27.1 1.4 2.3e-06 26.8 0.3 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EDO03850.1 - 0.0003 19.5 0.1 0.00051 18.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EDO03850.1 - 0.00038 20.7 0.1 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EDO03850.1 - 0.0014 18.5 0.1 0.0047 16.8 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EDO03850.1 - 0.0045 17.5 1.7 0.094 13.2 0.1 2.4 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.16 EDO03850.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDO03850.1 - 0.042 12.7 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 EDO03850.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lipoxygenase PF00305.14 EDO03851.1 - 8.3e-50 169.4 0.1 1.3e-49 168.8 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase His_Phos_2 PF00328.17 EDO03852.1 - 9.6e-24 84.3 0.0 1.2e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RINGv PF12906.2 EDO03853.1 - 2e-16 59.7 10.0 3.4e-16 59.0 6.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 EDO03853.1 - 0.033 13.8 6.0 0.053 13.1 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO03853.1 - 0.037 13.8 8.9 0.063 13.1 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EDO03853.1 - 0.21 11.4 2.3 0.54 10.1 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO03853.1 - 0.84 9.2 7.4 1.5 8.5 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EDO03853.1 - 0.86 9.7 4.4 2.1 8.5 3.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger CDC45 PF02724.9 EDO03853.1 - 1.2 7.1 2.7 1.8 6.4 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FANCL_C PF11793.3 EDO03853.1 - 1.2 9.1 5.8 2.4 8.1 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Baculo_PEP_C PF04513.7 EDO03854.1 - 0.0046 16.7 14.4 1.9 8.3 1.2 5.3 5 0 0 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EDO03854.1 - 0.0052 16.3 13.5 0.51 9.8 0.3 5.6 4 2 1 5 5 5 3 Apolipoprotein A1/A4/E domain Ferritin_2 PF13668.1 EDO03855.1 - 7.4e-14 51.8 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain HET PF06985.6 EDO03857.1 - 0.12 12.5 6.4 0.2 11.8 4.4 1.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) CDK2AP PF09806.4 EDO03857.1 - 0.18 12.0 16.7 0.23 11.6 11.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4456 PF14644.1 EDO03857.1 - 0.32 10.1 5.1 0.44 9.7 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) DUF2217 PF10265.4 EDO03857.1 - 0.52 9.0 9.1 0.57 8.8 6.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SR-25 PF10500.4 EDO03857.1 - 0.79 9.1 11.2 0.95 8.8 7.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG_C PF09333.6 EDO03857.1 - 0.86 9.8 4.8 6.8 6.9 3.3 2.1 1 1 0 1 1 1 0 ATG C terminal domain Macoilin PF09726.4 EDO03857.1 - 0.9 7.7 12.7 1 7.5 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EDO03857.1 - 1.8 8.3 9.8 2.1 8.1 6.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AATF-Che1 PF13339.1 EDO03857.1 - 4.6 7.3 8.0 16 5.6 4.8 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor zf-RING_2 PF13639.1 EDO03860.1 - 1e-06 28.4 4.5 1.4e-06 27.9 3.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO03860.1 - 2.9e-05 24.1 0.2 4.3e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO03860.1 - 0.0022 17.8 2.3 0.01 15.6 1.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO03860.1 - 0.043 13.4 2.8 0.058 13.0 1.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EDO03860.1 - 0.045 13.8 2.2 0.064 13.3 1.5 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EDO03860.1 - 0.047 13.7 4.3 0.075 13.0 3.0 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO03860.1 - 0.052 13.2 2.1 0.081 12.6 1.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Kelch_4 PF13418.1 EDO03861.1 - 1.6e-21 75.7 17.8 3.7e-09 36.2 0.2 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO03861.1 - 1.7e-21 75.4 3.4 8.3e-08 32.0 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.1 EDO03861.1 - 3.4e-20 71.6 8.5 2e-06 27.7 0.1 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO03861.1 - 2.9e-16 59.0 5.3 0.0013 18.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EDO03861.1 - 1.3e-12 46.9 3.8 0.0012 18.2 0.0 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EDO03861.1 - 8.7e-12 44.3 9.8 0.00093 18.8 0.0 5.0 6 0 0 6 6 6 3 Kelch motif Isochorismatase PF00857.15 EDO03862.1 - 7.2e-44 149.7 0.0 1.5e-43 148.7 0.0 1.5 2 0 0 2 2 2 1 Isochorismatase family AA_permease_2 PF13520.1 EDO03864.1 - 1.8e-59 201.3 48.9 2.2e-59 201.1 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO03864.1 - 2.6e-21 75.5 43.3 3.2e-21 75.2 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease NUDE_C PF04880.8 EDO03866.1 - 1.9e-19 70.6 10.0 1.9e-19 70.6 7.0 4.2 3 2 0 3 3 1 1 NUDE protein, C-terminal conserved region Prefoldin_2 PF01920.15 EDO03866.1 - 0.0081 15.9 26.9 0.27 11.0 4.8 5.0 3 1 2 5 5 5 1 Prefoldin subunit Chibby PF14645.1 EDO03866.1 - 0.061 13.2 10.7 1.2 8.9 0.3 2.8 1 1 1 2 2 2 0 Chibby family RTBV_P46 PF06216.6 EDO03866.1 - 0.096 11.5 11.0 0.17 10.7 2.9 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Allexi_40kDa PF05549.6 EDO03866.1 - 0.27 10.4 7.1 0.9 8.7 2.0 2.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.1 EDO03866.1 - 0.28 9.6 15.9 0.46 8.8 10.3 1.7 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EDO03866.1 - 0.39 10.5 36.4 0.19 11.6 16.2 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 EDO03866.1 - 0.81 10.0 30.4 0.051 13.8 2.8 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF904) WEMBL PF05701.6 EDO03866.1 - 0.85 7.9 27.7 3.5 5.9 19.2 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light IFT57 PF10498.4 EDO03866.1 - 1.9 7.1 19.2 0.32 9.6 9.6 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3584 PF12128.3 EDO03866.1 - 2.4 5.3 20.5 4 4.6 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EDO03866.1 - 2.8 7.7 30.8 1.2 8.8 12.7 3.7 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 EDO03866.1 - 4.1 6.8 9.1 1.5 8.2 2.1 3.1 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain ADIP PF11559.3 EDO03866.1 - 5.2 6.9 29.4 3.3 7.6 4.7 4.6 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EDO03866.1 - 5.4 6.5 35.0 0.98 8.9 2.5 5.0 2 1 3 5 5 5 0 Septum formation initiator Fib_alpha PF08702.5 EDO03866.1 - 7 6.7 14.4 4.4 7.4 4.8 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.14 EDO03866.1 - 8 5.9 32.8 4.1 6.8 20.8 1.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 EDO03866.1 - 8.4 5.7 29.3 36 3.6 18.9 3.0 2 1 0 2 2 2 0 Intermediate filament protein Rab5-bind PF09311.6 EDO03866.1 - 9.4 6.0 27.3 1.5 8.6 10.9 2.9 3 0 0 3 3 3 0 Rabaptin-like protein ACC_central PF08326.7 EDO03867.1 - 4.2e-272 904.4 0.0 5.3e-272 904.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EDO03867.1 - 6.7e-179 595.3 0.0 9.1e-179 594.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EDO03867.1 - 1.5e-52 177.9 0.0 2.9e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EDO03867.1 - 4.5e-24 84.6 0.1 8.9e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDO03867.1 - 2.5e-22 78.8 0.0 1.2e-19 70.2 0.0 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EDO03867.1 - 1.3e-15 56.8 0.1 2.9e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EDO03867.1 - 4.6e-10 39.5 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO03867.1 - 1.2e-07 30.7 0.0 8.6e-06 24.7 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDO03867.1 - 0.00033 20.1 0.0 0.00074 18.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EDO03867.1 - 0.0038 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EDO03867.1 - 0.022 14.1 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EDO03867.1 - 0.078 12.4 0.0 4 6.8 0.0 2.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain IU_nuc_hydro PF01156.14 EDO03868.1 - 5.7e-41 140.7 0.0 6.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase STAT_int PF02865.12 EDO03869.1 - 0.017 15.0 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain WD40 PF00400.27 EDO03870.1 - 7.7e-60 196.7 22.7 1.4e-10 40.6 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EDO03870.1 - 4.1e-13 48.8 0.2 8.7e-13 47.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO03870.1 - 2.6e-12 46.0 0.1 6.8e-12 44.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EDO03870.1 - 4.8e-11 41.5 10.1 0.017 13.2 0.1 5.4 3 3 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO03870.1 - 0.00082 18.2 0.3 0.073 11.8 0.1 2.5 2 1 0 2 2 2 2 Nup133 N terminal like PRANC PF09372.5 EDO03870.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.2 EDO03873.1 - 0.046 13.4 0.8 0.46 10.2 0.1 2.5 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 EDO03874.1 - 0.012 15.3 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EDO03875.1 - 0.14 11.9 0.2 0.19 11.5 0.1 1.3 1 1 0 1 1 1 0 F-box-like PA26 PF04636.8 EDO03877.1 - 0.031 13.0 0.0 0.034 12.8 0.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Exo_endo_phos PF03372.18 EDO03879.1 - 1.5e-12 48.0 0.1 2.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDO03879.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase IFNGR1 PF07140.6 EDO03881.1 - 0.023 14.3 0.1 0.027 14.1 0.1 1.0 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) GPDPase_memb PF10110.4 EDO03881.1 - 0.026 13.9 0.4 0.032 13.6 0.3 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase APG17 PF04108.7 EDO03882.1 - 9.8e-133 442.9 0.9 2.5e-132 441.5 0.6 1.6 1 1 0 1 1 1 1 Autophagy protein Apg17 PilJ PF13675.1 EDO03882.1 - 0.013 15.7 0.2 0.24 11.7 0.0 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sulfatase_C PF14707.1 EDO03882.1 - 0.13 12.5 0.3 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Lectin_N PF03954.9 EDO03882.1 - 1.4 8.2 6.0 2 7.7 0.2 3.1 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Cu-oxidase_3 PF07732.10 EDO03884.1 - 5.2e-43 145.5 9.0 7.7e-42 141.7 0.2 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDO03884.1 - 4.1e-35 120.2 11.3 3.5e-32 110.7 3.1 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EDO03884.1 - 3.7e-33 114.6 0.0 1.7e-30 106.0 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cutinase PF01083.17 EDO03884.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Cutinase UIM PF02809.15 EDO03887.1 - 0.0023 17.3 8.8 0.11 12.1 0.6 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif CobS_N PF12556.3 EDO03888.1 - 0.057 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal zf-C2H2 PF00096.21 EDO03889.1 - 3.6e-06 26.9 19.5 0.0022 18.1 4.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO03889.1 - 1.1e-05 25.4 17.6 0.0014 18.7 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger CCAP PF11105.3 EDO03889.1 - 0.033 13.9 0.3 0.058 13.1 0.2 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-UDP PF14569.1 EDO03889.1 - 2 8.2 4.9 0.3 10.8 0.6 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF3260 PF11658.3 EDO03891.1 - 0.16 10.1 0.1 0.17 10.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF3446 PF11928.3 EDO03894.1 - 0.016 15.4 8.4 0.018 15.2 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) CAF-1_p150 PF11600.3 EDO03894.1 - 0.22 10.8 0.9 0.24 10.7 0.6 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SSP160 PF06933.6 EDO03894.1 - 0.74 7.7 15.8 0.78 7.6 11.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TrbI PF03743.9 EDO03894.1 - 1.2 8.6 4.7 1.3 8.4 3.3 1.1 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Mucin PF01456.12 EDO03894.1 - 1.7 8.4 14.0 2 8.1 9.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF515 PF04415.7 EDO03894.1 - 2.7 6.1 6.7 2.9 6.0 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sporozoite_P67 PF05642.6 EDO03894.1 - 3.8 5.2 13.2 4.2 5.1 9.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_76 PF03663.9 EDO03895.1 - 0.09 12.1 0.2 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 CBM_21 PF03370.8 EDO03901.1 - 2.8e-34 117.5 3.3 5.7e-34 116.4 2.3 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit TAF4 PF05236.9 EDO03904.1 - 2.8 7.1 7.6 3.1 6.9 5.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BolA PF01722.13 EDO03907.1 - 1.2e-16 60.4 0.0 1.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Lipase_GDSL_2 PF13472.1 EDO03908.1 - 1e-19 71.3 0.0 1.3e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDO03908.1 - 1.2e-14 54.7 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RVT_1 PF00078.22 EDO03911.1 - 3.5e-35 121.3 1.7 6.5e-35 120.4 1.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO03911.1 - 5.1e-15 55.9 0.6 2.7e-14 53.6 0.1 2.3 2 0 0 2 2 2 1 RNase H zf-CCHC_4 PF14392.1 EDO03912.1 - 0.028 14.0 2.3 0.031 13.9 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDO03912.1 - 0.41 10.3 10.2 2.2 8.0 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle Ribonuclease PF00545.15 EDO03913.1 - 2e-16 59.8 0.0 2.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 ribonuclease AlphaC_N PF08829.5 EDO03915.1 - 0.0033 16.8 1.1 0.0046 16.3 0.8 1.2 1 0 0 1 1 1 1 Alpha C protein N terminal F_bP_aldolase PF01116.15 EDO03919.1 - 1.4e-80 270.4 0.0 1.6e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NanE PF04131.9 EDO03919.1 - 0.02 13.8 0.1 1.4 7.8 0.1 2.5 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Soyouz_module PF14313.1 EDO03919.1 - 0.038 13.5 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Glyco_hydro_16 PF00722.16 EDO03920.1 - 0.0004 19.7 0.1 0.00095 18.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 EDO03921.1 - 2.6e-116 388.8 29.2 2.9e-116 388.7 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO03921.1 - 1.9e-21 76.1 40.8 2.4e-21 75.8 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Velvet PF11754.3 EDO03925.1 - 4.8e-07 29.5 0.0 1.3e-06 28.1 0.0 1.6 1 1 1 2 2 2 1 Velvet factor tRNA-synt_1d PF00750.14 EDO03926.1 - 3.2e-76 256.4 7.4 1.1e-75 254.6 5.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EDO03926.1 - 7.5e-30 103.3 0.8 1.9e-29 102.0 0.5 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EDO03926.1 - 6e-05 23.5 0.0 0.00021 21.7 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain HeLo PF14479.1 EDO03927.1 - 1.7e-07 31.2 1.6 0.0058 16.4 0.4 2.5 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase PF00069.20 EDO03927.1 - 0.016 14.3 0.1 0.052 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain DDE_1 PF03184.14 EDO03928.1 - 3.6e-26 91.6 1.4 2e-23 82.6 0.0 2.5 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03928.1 - 2e-07 30.7 0.2 8.7e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO03928.1 - 0.013 15.3 6.7 0.028 14.3 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 EDO03929.1 - 3e-50 170.4 0.0 3.5e-49 166.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO03929.1 - 4.2e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO03929.1 - 0.00017 21.1 0.7 0.0005 19.6 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3248 PF11609.3 EDO03929.1 - 0.041 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) RVT_1 PF00078.22 EDO03930.1 - 1.2e-35 122.8 0.6 2.6e-35 121.7 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO03930.1 - 8.2e-15 55.3 0.0 2.1e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDO03930.1 - 0.011 16.0 0.1 0.04 14.2 0.0 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EDO03930.1 - 0.041 13.4 0.4 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF1443 PF07280.6 EDO03932.1 - 0.024 14.2 0.4 0.042 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) Mesothelin PF06060.7 EDO03933.1 - 0.019 13.0 0.0 0.024 12.7 0.0 1.0 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DUF3899 PF13038.1 EDO03933.1 - 0.08 13.1 0.2 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DDE_1 PF03184.14 EDO03934.1 - 3.2e-05 23.1 0.0 3.2e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CIMR PF00878.13 EDO03937.1 - 0.084 12.6 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat His_Phos_1 PF00300.17 EDO03938.1 - 1.9e-05 24.8 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1206 PF06724.6 EDO03939.1 - 0.38 10.5 2.1 0.74 9.6 1.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) RIO1 PF01163.17 EDO03940.1 - 4.7e-70 234.7 0.0 4.7e-70 234.7 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EDO03940.1 - 0.00023 20.2 0.2 0.0036 16.3 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO03940.1 - 0.0091 15.7 0.2 3.2 7.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family SMC_hinge PF06470.8 EDO03941.1 - 4.5e-31 107.3 0.8 2e-30 105.2 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EDO03941.1 - 1.1e-24 86.9 58.6 2.2e-20 72.8 38.9 3.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO03941.1 - 1.3e-08 35.2 1.6 7.5e-07 29.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain TMEM192 PF14802.1 EDO03941.1 - 0.0029 16.5 0.8 0.0071 15.2 0.5 1.6 1 0 0 1 1 1 1 TMEM192 family TMF_TATA_bd PF12325.3 EDO03941.1 - 0.0059 16.3 3.0 0.0059 16.3 2.1 8.8 4 2 4 8 8 8 1 TATA element modulatory factor 1 TATA binding Glyco_hydro_67M PF07488.7 EDO03942.1 - 0.06 12.2 0.0 0.064 12.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain DEAD PF00270.24 EDO03944.1 - 6.7e-41 139.5 0.9 1.2e-40 138.8 0.6 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO03944.1 - 7.5e-22 76.9 0.0 9.8e-12 44.5 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EDO03944.1 - 1.5e-05 24.8 0.3 8.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CarboxypepD_reg PF13620.1 EDO03945.1 - 0.068 13.2 4.1 0.082 12.9 0.7 2.9 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain U3_snoRNA_assoc PF08297.6 EDO03949.1 - 1.8e-19 69.7 0.3 1.8e-19 69.7 0.2 3.3 2 1 0 2 2 2 1 U3 snoRNA associated TPR_12 PF13424.1 EDO03950.1 - 6.3e-09 35.6 0.2 0.0057 16.5 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat Sel1 PF08238.7 EDO03950.1 - 6.2e-08 33.0 6.4 0.014 16.0 0.0 5.4 5 1 1 6 6 6 2 Sel1 repeat TPR_2 PF07719.12 EDO03950.1 - 1.5e-07 30.7 3.6 0.011 15.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO03950.1 - 2.1e-07 30.2 0.9 0.044 13.4 0.1 4.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO03950.1 - 5.3e-07 30.1 0.7 0.022 15.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO03950.1 - 1.1e-06 28.7 1.0 0.11 13.1 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO03950.1 - 4.2e-06 26.3 0.1 0.00086 18.8 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.1 EDO03950.1 - 1.6e-05 24.6 0.0 0.37 10.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDO03950.1 - 9.1e-05 22.6 3.0 0.71 10.4 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO03950.1 - 0.00011 21.7 4.3 0.1 12.4 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO03950.1 - 0.0002 20.9 0.0 0.023 14.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO03950.1 - 0.00032 20.7 0.1 0.63 10.2 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDO03950.1 - 0.00051 20.0 0.1 3 8.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO03950.1 - 0.00063 20.0 3.6 1 9.7 0.3 3.7 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDO03950.1 - 0.0069 15.4 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_11 PF08241.7 EDO03952.1 - 9.8e-14 51.6 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO03952.1 - 4.3e-13 48.9 0.0 1.2e-11 44.1 0.0 2.2 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDO03952.1 - 6.4e-08 33.1 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO03952.1 - 1.4e-07 31.2 0.0 2.7e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO03952.1 - 1.6e-07 31.6 0.0 2.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO03952.1 - 2.8e-07 30.4 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO03952.1 - 4.4e-07 30.2 0.0 1e-06 29.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO03952.1 - 1.1e-06 28.6 0.0 3.8e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO03952.1 - 0.00043 19.6 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EDO03952.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein FmrO PF07091.6 EDO03952.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 EDO03952.1 - 0.11 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF3449 PF11931.3 EDO03953.1 - 4.6e-75 251.4 0.4 9.2e-75 250.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EDO03953.1 - 4.6e-13 48.4 0.1 9.3e-13 47.4 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EDO03953.1 - 2.5e-08 33.8 2.9 5e-06 26.5 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO03953.1 - 8.9e-08 32.0 3.6 6.8e-06 26.0 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDO03953.1 - 0.00043 20.3 0.1 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EDO03953.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF951) Desulfoferrod_N PF06397.7 EDO03953.1 - 0.2 11.0 1.6 0.42 10.0 1.1 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Vmethyltransf_C PF08456.5 EDO03953.1 - 0.41 10.0 4.5 1.5 8.1 0.0 2.6 3 1 0 3 3 3 0 Viral methyltransferase C-terminal zf-C2H2 PF00096.21 EDO03953.1 - 0.49 10.8 3.4 15 6.1 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Myb_CC_LHEQLE PF14379.1 EDO03953.1 - 0.83 9.2 6.8 17 5.0 4.7 2.8 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif DEAD PF00270.24 EDO03954.1 - 1e-40 138.9 0.3 2.3e-40 137.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO03954.1 - 3.3e-29 100.5 0.2 6.9e-29 99.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EDO03954.1 - 0.0072 15.6 0.3 0.015 14.6 0.1 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 EDO03954.1 - 0.012 15.1 0.6 0.03 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO03954.1 - 0.016 14.9 0.2 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EDO03954.1 - 0.033 14.0 0.1 0.069 12.9 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDO03954.1 - 0.046 13.4 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EDO03954.1 - 0.14 12.3 0.5 0.57 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain DUF1996 PF09362.5 EDO03955.1 - 6e-74 248.6 0.1 8.2e-74 248.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) gag-asp_proteas PF13975.1 EDO03956.1 - 5.1e-15 55.0 0.1 1e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 EDO03956.1 - 1.9e-12 47.0 0.1 6.3e-06 25.7 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EDO03956.1 - 6.1e-10 39.4 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EDO03956.1 - 5.2e-09 36.0 0.0 2.1e-08 34.1 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO03956.1 - 1.8e-06 27.6 2.6 3.2e-06 26.8 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EDO03956.1 - 7e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDO03956.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EDO03956.1 - 0.036 13.4 0.1 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger zf-CCHC_5 PF14787.1 EDO03956.1 - 0.1 12.1 9.4 0.025 14.0 4.1 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger APG6 PF04111.7 EDO03957.1 - 0.18 10.8 5.9 0.24 10.4 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tox-ODYAM1 PF15642.1 EDO03957.1 - 0.27 9.8 2.0 0.34 9.5 1.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus SET PF00856.23 EDO03958.1 - 8.5e-10 39.1 0.0 2.2e-08 34.5 0.0 2.4 1 1 1 2 2 2 2 SET domain Aldedh PF00171.17 EDO03959.1 - 1.1e-134 449.2 0.0 1.3e-134 448.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDO03959.1 - 0.062 12.0 0.0 0.16 10.6 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Flu_C_NS1 PF03506.8 EDO03962.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Influenza C non-structural protein (NS1) TOM13 PF08219.6 EDO03963.1 - 1.8e-30 104.4 0.0 4.8e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EDO03963.1 - 6.2e-26 91.2 3.4 9.4e-26 90.7 2.3 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DEDD_Tnp_IS110 PF01548.12 EDO03963.1 - 0.35 10.5 9.9 0.64 9.6 6.9 1.4 1 0 0 1 1 1 0 Transposase SEP PF08059.8 EDO03964.1 - 4.4e-29 100.6 0.0 1.2e-28 99.1 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EDO03964.1 - 8e-13 47.6 1.1 1.2e-12 47.0 0.7 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EDO03964.1 - 4.7e-11 42.5 0.1 1.1e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 UBX domain TAP_C PF03943.8 EDO03964.1 - 0.037 13.4 0.2 0.058 12.8 0.2 1.3 1 0 0 1 1 1 0 TAP C-terminal domain adh_short PF00106.20 EDO03967.1 - 7.8e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO03967.1 - 2.2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDO03967.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDO03967.1 - 0.0006 19.3 0.0 0.0041 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDO03967.1 - 0.0039 16.9 0.8 0.0072 16.1 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EDO03967.1 - 0.0044 15.9 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EDO03967.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 KR domain TPR_11 PF13414.1 EDO03968.1 - 9.2e-06 25.2 0.0 4.4e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 EDO03968.1 - 2e-05 24.3 0.3 5.2e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBN2_2 PF14227.1 EDO03968.1 - 0.007 15.9 1.0 2.4 7.7 0.0 2.6 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DnaJ PF00226.26 EDO03968.1 - 0.0082 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 EDO03968.1 - 0.075 12.9 0.1 9.4 6.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1688 PF07958.6 EDO03970.1 - 4.5e-180 598.6 0.0 5.1e-180 598.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) HTH_psq PF05225.11 EDO03973.1 - 1.1e-09 37.6 0.2 3.2e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO03973.1 - 7.7e-07 28.8 0.3 2.3e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF3404 PF11884.3 EDO03973.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HTH_28 PF13518.1 EDO03973.1 - 0.061 13.3 0.5 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDO03973.1 - 0.085 12.7 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 NUMOD1 domain HTH_29 PF13551.1 EDO03973.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 EDO03973.1 - 0.15 11.7 0.5 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DDE_1 PF03184.14 EDO03974.1 - 1.7e-51 174.4 0.0 4e-51 173.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO03974.1 - 4.4e-10 39.2 1.0 1.2e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO03974.1 - 7.4e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO03974.1 - 0.005 16.7 6.0 0.012 15.4 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF904 PF06005.7 EDO03974.1 - 0.076 13.3 0.6 0.19 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) NAP PF00956.13 EDO03975.1 - 8.8e-47 159.2 0.1 1.4e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RPA_interact_M PF14767.1 EDO03975.1 - 0.27 12.0 7.8 25 5.6 0.3 3.5 3 0 0 3 3 3 0 Replication protein A interacting middle Asparaginase PF00710.15 EDO03976.1 - 2.6e-100 335.3 0.0 3.2e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EDO03976.1 - 3.5e-12 46.4 0.1 7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO03976.1 - 6.8e-09 35.0 0.0 2.3e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDO03976.1 - 4.1e-08 33.2 0.2 2.9e-07 30.5 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO03976.1 - 9.4e-07 29.1 0.0 1.2e-05 25.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO03976.1 - 0.0015 18.5 0.0 0.77 10.1 0.0 3.7 5 0 0 5 5 5 1 Ankyrin repeat DUF2629 PF10945.3 EDO03976.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2629) HECT_2 PF09814.4 EDO03978.1 - 2.2e-37 128.6 0.0 2.5e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-CSL PF05207.8 EDO03978.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF4243 PF14027.1 EDO03979.1 - 1.2e-87 294.4 0.2 1.5e-87 294.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3885 PF13021.1 EDO03979.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Ank_2 PF12796.2 EDO03980.1 - 1.6e-34 118.1 1.3 4.9e-20 71.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO03980.1 - 2.6e-31 107.4 3.1 2.9e-10 40.3 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EDO03980.1 - 1.1e-30 103.8 1.4 1.5e-08 34.0 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EDO03980.1 - 3.7e-25 85.4 2.3 5.6e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EDO03980.1 - 1.2e-21 76.2 0.5 1.4e-10 41.0 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) CUE PF02845.11 EDO03985.1 - 5e-12 45.0 0.0 7.7e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 EDO03985.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF3697 PF12478.3 EDO03985.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 DUF1797 PF08796.5 EDO03987.1 - 0.087 12.7 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) HET PF06985.6 EDO03991.1 - 8.7e-12 45.3 0.8 1.5e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Gastrin PF00918.12 EDO03991.1 - 0.026 15.3 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PGM_PMM_I PF02878.11 EDO03992.1 - 2e-31 108.2 0.0 2.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDO03992.1 - 1.2e-24 86.5 0.0 2.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EDO03992.1 - 2.5e-14 53.4 0.0 5.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDO03992.1 - 8.2e-12 44.9 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EDO03993.1 - 4.2e-26 92.1 0.0 4.8e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease HTH_Tnp_Tc5 PF03221.11 EDO03994.1 - 7.9e-07 28.8 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO03994.1 - 0.019 14.0 0.1 0.14 11.3 0.0 2.3 2 1 0 2 2 2 0 DDE superfamily endonuclease Phage_CI_repr PF07022.8 EDO03994.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DDE_1 PF03184.14 EDO03998.1 - 7.2e-37 126.6 0.1 7.4e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDO03998.1 - 2.7e-06 27.2 0.1 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease C_GCAxxG_C_C PF09719.5 EDO03999.1 - 0.11 12.2 0.3 0.15 11.8 0.2 1.3 1 1 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Chromate_transp PF02417.10 EDO04000.1 - 0.081 12.5 0.2 0.086 12.4 0.1 1.0 1 0 0 1 1 1 0 Chromate transporter ABC_tran PF00005.22 EDO04003.1 - 1.8e-33 115.7 0.0 6.1e-33 114.0 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDO04003.1 - 1e-05 25.6 0.0 0.031 14.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain ABC_membrane PF00664.18 EDO04003.1 - 0.00067 19.1 0.5 0.0014 18.0 0.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF258 PF03193.11 EDO04003.1 - 0.017 14.2 0.0 0.049 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDO04003.1 - 0.047 13.5 0.1 0.26 11.2 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDO04003.1 - 0.1 12.1 0.3 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tim44 PF04280.10 EDO04005.1 - 2.4e-33 115.2 0.1 3.8e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 Tim44-like domain Ribosomal_S11 PF00411.14 EDO04006.1 - 1.5e-09 38.0 0.1 2.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Peptidase_C97 PF05903.9 EDO04007.1 - 1.2e-28 99.7 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EDO04007.1 - 7.3e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 EDO04007.1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) YchF-GTPase_C PF06071.8 EDO04008.1 - 2.8e-31 107.1 0.4 6.8e-31 105.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDO04008.1 - 9.1e-14 51.4 0.0 2.4e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO04008.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EDO04008.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.18 EDO04008.1 - 0.032 14.0 0.0 0.59 9.9 0.0 2.5 2 1 0 3 3 3 0 Dynamin family AAA_23 PF13476.1 EDO04008.1 - 0.066 13.5 2.5 0.35 11.1 1.5 2.3 1 1 0 1 1 1 0 AAA domain SecA_PP_bind PF01043.15 EDO04008.1 - 0.12 12.6 0.2 0.45 10.8 0.0 2.0 2 1 0 2 2 2 0 SecA preprotein cross-linking domain TPR_11 PF13414.1 EDO04009.1 - 1.6e-19 69.3 7.3 4.2e-16 58.3 1.9 2.7 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDO04009.1 - 3.3e-15 54.9 5.1 3.7e-06 26.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04009.1 - 3.7e-15 54.5 4.1 1.6e-05 24.4 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO04009.1 - 1.1e-08 35.5 6.4 0.00016 22.2 1.9 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04009.1 - 4.1e-08 33.1 2.3 0.011 16.2 0.5 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04009.1 - 9.4e-07 28.5 2.8 0.072 13.3 0.1 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04009.1 - 4.1e-06 26.6 3.4 0.00016 21.5 1.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04009.1 - 9.9e-06 25.8 1.3 9.9e-06 25.8 0.9 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04009.1 - 2.6e-05 23.6 10.0 0.21 11.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04009.1 - 0.00011 21.7 0.1 0.78 9.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 EDO04009.1 - 0.00038 20.7 0.3 0.47 10.7 0.1 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 EDO04009.1 - 0.0018 18.0 0.4 0.015 15.1 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 EDO04009.1 - 0.0064 15.9 2.6 0.012 15.0 0.7 2.1 2 0 0 2 2 2 1 XPC-binding domain TPR_3 PF07720.7 EDO04009.1 - 0.029 14.1 0.1 0.081 12.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO04009.1 - 0.058 13.3 0.5 8.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HRDC PF00570.18 EDO04009.1 - 0.14 11.9 0.3 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 HRDC domain DUF4398 PF14346.1 EDO04009.1 - 8.2 6.5 18.7 0.92 9.5 4.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DDE_1 PF03184.14 EDO04010.1 - 3.6e-51 173.3 0.0 6.4e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04010.1 - 1.3e-10 40.5 0.7 3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO04010.1 - 2.7e-08 33.6 0.0 4.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04010.1 - 5.5e-07 29.3 0.1 3.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO04010.1 - 0.012 15.5 7.4 0.025 14.5 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Hydrolase_6 PF13344.1 EDO04011.1 - 3.9e-21 74.8 0.0 9.1e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO04011.1 - 1.6e-19 69.4 0.0 4.1e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EDO04011.1 - 0.00014 22.1 0.0 0.02 15.1 0.0 2.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO04011.1 - 0.012 16.0 0.0 0.22 11.9 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4501 PF14946.1 EDO04013.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Aldo_ket_red PF00248.16 EDO04014.1 - 1.5e-56 191.3 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LysM PF01476.15 EDO04014.1 - 0.088 12.7 0.0 3.7 7.5 0.0 3.2 3 0 0 3 3 3 0 LysM domain RVT_1 PF00078.22 EDO04015.1 - 4.3e-24 85.0 0.1 8.1e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDO04015.1 - 0.00018 20.8 0.0 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EDO04015.1 - 0.094 12.5 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EDO04015.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Dus PF01207.12 EDO04018.1 - 7e-59 199.1 0.0 8.5e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EDO04018.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Resolvase PF00239.16 EDO04018.1 - 0.031 14.1 0.3 0.097 12.5 0.2 1.8 1 1 1 2 2 2 0 Resolvase, N terminal domain PDE8 PF08629.5 EDO04018.1 - 0.13 12.0 0.9 0.36 10.6 0.1 2.2 2 0 0 2 2 2 0 PDE8 phosphodiesterase LRR_8 PF13855.1 EDO04023.1 - 4.6e-05 23.0 6.8 0.0029 17.3 0.6 4.1 3 1 1 4 4 4 2 Leucine rich repeat RRN3 PF05327.6 EDO04023.1 - 0.039 12.0 0.1 0.057 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 F-box-like PF12937.2 EDO04023.1 - 0.067 12.9 5.3 0.041 13.6 1.2 2.6 2 1 0 2 2 2 0 F-box-like DDE_1 PF03184.14 EDO04025.1 - 3.7e-48 163.5 0.0 8.7e-48 162.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04025.1 - 7.1e-10 38.2 0.6 5.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDO04025.1 - 9.7e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_24 PF13412.1 EDO04025.1 - 0.0036 16.6 0.5 0.0087 15.4 0.4 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding NUMOD1 PF07453.8 EDO04025.1 - 0.059 13.2 0.2 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 NUMOD1 domain HTH_23 PF13384.1 EDO04025.1 - 0.19 11.4 1.2 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain zf-CCHC PF00098.18 EDO04025.1 - 0.8 9.7 12.9 0.041 13.8 5.1 1.8 2 0 0 2 2 2 0 Zinc knuckle F-box-like PF12937.2 EDO04028.1 - 0.00036 20.1 0.0 0.00083 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO04028.1 - 0.11 12.1 2.2 0.41 10.3 0.5 2.7 2 1 0 2 2 2 0 F-box domain DUF1765 PF08578.5 EDO04030.1 - 1.3e-05 25.2 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) WSC PF01822.14 EDO04031.1 - 4.2e-11 42.6 2.7 4.2e-11 42.6 1.9 1.8 2 0 0 2 2 2 1 WSC domain Cyclin_N PF00134.18 EDO04032.1 - 1.2e-05 24.8 0.4 0.00016 21.2 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain adh_short PF00106.20 EDO04035.1 - 1.5e-18 67.3 1.2 1.9e-18 66.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO04035.1 - 2.6e-08 33.7 0.5 3.9e-08 33.1 0.4 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDO04035.1 - 3.5e-06 26.1 0.1 4.3e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EDO04035.1 - 0.0093 15.7 0.8 0.063 13.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EDO04035.1 - 0.011 15.8 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EDO04035.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family BBE PF08031.7 EDO04037.1 - 6.7e-12 45.1 1.9 6.7e-12 45.1 1.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EDO04037.1 - 0.0042 16.2 0.1 0.0062 15.7 0.1 1.3 1 1 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding PRANC PF09372.5 EDO04040.1 - 0.0074 16.2 0.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 PRANC domain DDE_1 PF03184.14 EDO04043.1 - 1.1e-11 44.3 0.1 3.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04043.1 - 3.7e-09 36.2 0.0 7.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PH_8 PF15409.1 EDO04043.1 - 0.15 12.1 0.6 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 EDO04046.1 - 6.7e-54 182.7 0.1 9.9e-54 182.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04046.1 - 3.3e-25 88.6 0.3 9e-25 87.2 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDO04046.1 - 0.0018 17.1 0.1 0.0027 16.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EDO04046.1 - 0.089 12.1 0.1 0.22 10.8 0.1 1.7 1 1 0 1 1 1 0 RIO1 family TMA7 PF09072.5 EDO04047.1 - 5.6e-08 33.1 9.0 8.1e-08 32.6 6.3 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 Phlebovirus_NSM PF07246.6 EDO04047.1 - 0.0035 16.5 1.1 0.0037 16.4 0.8 1.0 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF1674 PF07896.7 EDO04047.1 - 0.14 12.4 2.2 0.23 11.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1674) SchA_CurD PF04486.7 EDO04047.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 SchA/CurD like domain DNA_pol_B_palm PF14792.1 EDO04048.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Pup PF05639.6 EDO04049.1 - 0.0037 17.7 0.8 0.0048 17.3 0.4 1.4 1 1 0 1 1 1 1 Pup-like protein Annexin PF00191.15 EDO04050.1 - 5.8e-41 138.2 0.3 2e-12 46.8 0.0 3.2 3 0 0 3 3 3 3 Annexin DUF515 PF04415.7 EDO04050.1 - 0.025 12.8 0.1 0.038 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Trypsin PF00089.21 EDO04052.1 - 1.7e-60 204.3 5.9 2e-60 204.1 4.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EDO04052.1 - 0.0089 16.0 0.1 0.026 14.5 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain AA_permease_2 PF13520.1 EDO04053.1 - 5.9e-15 54.7 8.2 6.5e-15 54.5 5.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO04053.1 - 1.8e-07 29.8 6.4 2.1e-07 29.6 4.4 1.0 1 0 0 1 1 1 1 Amino acid permease VirB3 PF05101.8 EDO04053.1 - 0.31 11.0 0.1 0.31 11.0 0.0 2.1 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein AA_permease_2 PF13520.1 EDO04054.1 - 3.2e-07 29.2 11.6 3.7e-07 29.0 8.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO04054.1 - 0.00092 17.6 5.0 0.0011 17.3 3.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4395 PF14340.1 EDO04054.1 - 1.4 9.0 5.2 6.9 6.7 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) EMP24_GP25L PF01105.19 EDO04056.1 - 0.035 13.8 2.4 0.041 13.6 1.6 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mut7-C PF01927.11 EDO04056.1 - 0.058 13.3 2.7 0.06 13.3 1.9 1.0 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF3484 PF11983.3 EDO04056.1 - 0.14 13.0 2.8 0.14 12.9 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) Baculo_LEF5 PF04838.7 EDO04056.1 - 0.15 11.7 2.9 0.18 11.5 2.0 1.0 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 NHR2 PF08788.6 EDO04056.1 - 0.24 10.9 4.6 0.31 10.5 3.1 1.4 1 1 0 1 1 1 0 NHR2 domain like Myb_DNA-bind_4 PF13837.1 EDO04056.1 - 2.3 8.4 7.0 2.5 8.2 4.9 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.20 EDO04060.1 - 3.9e-56 190.0 0.0 5.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04060.1 - 2e-25 89.3 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO04060.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO04060.1 - 0.0051 15.9 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EDO04060.1 - 0.032 13.0 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EDO04060.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Period_C PF12114.3 EDO04060.1 - 1.1 8.8 3.4 1.6 8.2 2.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RINGv PF12906.2 EDO04064.1 - 3.9e-07 29.9 6.0 6.7e-07 29.2 4.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EDO04064.1 - 0.0023 17.7 5.7 0.0043 16.8 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EDO04064.1 - 0.0039 17.1 4.3 0.0067 16.3 3.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EDO04064.1 - 0.37 10.9 4.6 0.74 9.9 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF604 PF04646.7 EDO04065.1 - 6.5e-09 35.3 0.3 1e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EDO04065.1 - 1.3e-06 27.7 0.0 3.3e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Fringe-like TroA PF01297.12 EDO04065.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family Toprim_3 PF13362.1 EDO04065.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Toprim domain GalKase_gal_bdg PF10509.4 EDO04066.1 - 2.1e-20 71.7 0.0 4.5e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EDO04066.1 - 9.9e-16 57.7 0.0 5.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EDO04066.1 - 6.9e-14 51.6 1.4 1.7e-12 47.2 1.1 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain Sigma70_r4_2 PF08281.7 EDO04066.1 - 0.13 11.7 0.1 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_2 PF07719.12 EDO04067.1 - 1.6e-06 27.6 0.3 0.59 10.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04067.1 - 1.7e-06 27.8 0.1 8.7e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDO04067.1 - 9.2e-06 25.6 0.3 5.3 7.7 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04067.1 - 2.6e-05 24.4 1.1 0.018 15.4 0.0 3.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO04067.1 - 0.0001 21.8 1.3 0.029 14.0 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_10 PF13374.1 EDO04067.1 - 0.00032 20.5 0.8 0.054 13.4 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO04067.1 - 0.00061 20.0 0.4 5.1 7.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04067.1 - 0.001 18.5 0.1 14 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04067.1 - 0.0011 18.6 1.2 5.6 7.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO04067.1 - 0.0015 19.1 1.6 0.0068 17.0 0.0 2.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04067.1 - 0.0026 18.2 1.3 11 7.0 0.0 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04067.1 - 0.0084 15.8 0.8 2.3 8.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EDO04067.1 - 0.11 12.5 0.2 7.8 6.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPP_enzyme_N PF02776.13 EDO04068.1 - 1.4e-53 180.9 0.1 3.9e-53 179.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDO04068.1 - 2.8e-50 169.8 0.4 2.3e-47 160.3 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDO04068.1 - 6e-37 126.4 0.6 1.6e-36 125.0 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 EDO04069.1 - 1.1e-59 201.2 4.0 2.3e-59 200.2 2.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO04069.1 - 5.9e-35 120.4 6.7 5.9e-35 120.4 4.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO04069.1 - 1e-28 101.2 0.0 1.5e-27 97.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO04069.1 - 7.3e-18 63.7 0.0 1.6e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDO04069.1 - 1.3e-16 60.3 0.0 3.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDO04069.1 - 9.5e-14 52.0 0.0 2.3e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO04069.1 - 0.0021 17.7 1.4 0.015 14.9 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Transgly_assoc PF04226.8 EDO04069.1 - 0.028 14.4 0.8 0.028 14.4 0.5 2.8 2 1 1 3 3 3 0 Transglycosylase associated protein DUF2207 PF09972.4 EDO04069.1 - 0.39 9.2 1.8 0.66 8.4 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Chordopox_RPO7 PF05864.7 EDO04071.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ABC_tran PF00005.22 EDO04072.1 - 5e-11 43.0 0.0 7.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EDO04072.1 - 0.00065 20.5 0.0 0.00095 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO04072.1 - 0.0024 18.0 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDO04072.1 - 0.0024 17.0 0.1 0.0039 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO04072.1 - 0.0025 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EDO04072.1 - 0.003 17.4 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDO04072.1 - 0.0044 16.5 0.6 0.0087 15.5 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EDO04072.1 - 0.015 14.7 0.1 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EDO04072.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EDO04072.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EDO04072.1 - 0.021 14.4 0.3 0.034 13.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Phosphoprotein PF00922.12 EDO04072.1 - 0.036 13.2 0.0 0.078 12.1 0.0 1.4 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein DUF87 PF01935.12 EDO04072.1 - 0.037 13.8 0.3 0.059 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EDO04072.1 - 0.039 13.3 0.2 0.063 12.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO04072.1 - 0.054 13.6 0.1 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EDO04072.1 - 0.063 12.8 0.3 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Spore_IV_A PF09547.5 EDO04072.1 - 0.065 11.9 0.0 0.38 9.3 0.0 1.8 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) PRK PF00485.13 EDO04072.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EDO04072.1 - 0.15 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EDO04072.1 - 0.17 11.3 0.3 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pkinase PF00069.20 EDO04073.1 - 2.3e-12 46.6 0.0 7.8e-12 44.8 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04073.1 - 0.096 11.7 0.1 0.3 10.1 0.0 1.8 3 0 0 3 3 3 0 Protein tyrosine kinase UCH PF00443.24 EDO04075.1 - 6.9e-32 110.6 2.4 3.4e-25 88.6 0.1 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO04075.1 - 3.7e-10 39.7 1.8 1.3e-09 37.9 1.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_N PF01281.14 EDO04076.1 - 6.5e-14 50.9 1.5 8.9e-14 50.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EDO04076.1 - 0.00066 19.7 0.8 0.098 12.7 0.5 2.7 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain DUF3858 PF12970.2 EDO04076.1 - 0.1 12.3 0.3 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) F_bP_aldolase PF01116.15 EDO04078.1 - 2.4e-97 325.5 0.0 2.7e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.1 EDO04078.1 - 0.028 14.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Enolase C-terminal domain-like COP-gamma_platf PF08752.5 EDO04078.1 - 0.04 13.7 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain Oxysterol_BP PF01237.13 EDO04079.1 - 4.1e-92 308.4 0.1 5e-92 308.1 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RVT_1 PF00078.22 EDO04080.1 - 8.2e-31 107.0 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO04080.1 - 8.3e-09 35.8 0.6 1.7e-06 28.4 0.1 2.3 1 1 1 2 2 2 2 RNase H DUF993 PF06187.6 EDO04080.1 - 0.05 12.1 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Curto_V3 PF07436.6 EDO04081.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Curtovirus V3 protein Brix PF04427.13 EDO04083.1 - 3.2e-56 190.0 0.0 4.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain HD_4 PF13328.1 EDO04083.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.1 3 0 0 3 3 3 0 HD domain DEAD PF00270.24 EDO04084.1 - 1.9e-45 154.3 0.0 3.2e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO04084.1 - 1e-27 95.7 0.0 2.2e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO04084.1 - 0.0012 18.7 0.0 0.0097 15.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CATSPERD PF15020.1 EDO04084.1 - 0.099 10.6 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta CoA_transf_3 PF02515.12 EDO04085.1 - 2.1e-59 200.0 0.0 3.5e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 EDO04085.1 - 2.2e-08 33.6 8.1 4.7e-08 32.6 5.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDO04085.1 - 0.0045 16.2 3.4 0.0045 16.2 2.4 2.1 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 EDO04085.1 - 0.034 13.4 4.2 0.023 14.0 1.3 1.8 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EDO04085.1 - 0.56 9.9 9.1 0.053 13.2 2.8 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EDO04085.1 - 1.1 9.0 4.3 0.33 10.7 1.0 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1749 PF08538.5 EDO04086.1 - 8.9e-100 333.4 0.0 9.9e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EDO04086.1 - 8.8e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO04086.1 - 0.0005 19.8 0.0 0.00088 19.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EDO04086.1 - 0.025 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EDO04086.1 - 0.035 13.5 0.0 4.1 6.7 0.0 2.2 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) MRP-L28 PF09812.4 EDO04087.1 - 2.5e-06 27.4 0.1 3.1e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EDO04088.1 - 7.7e-46 155.4 0.0 9.1e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO04088.1 - 1e-15 58.2 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO04088.1 - 1.4e-06 27.6 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO04088.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDO04088.1 - 0.015 14.7 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EDO04088.1 - 0.065 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NST1 PF13945.1 EDO04089.1 - 4.4e-65 219.3 3.8 4.4e-65 219.3 2.7 5.2 3 2 2 5 5 5 1 Salt tolerance down-regulator DUF2625 PF10946.3 EDO04090.1 - 0.16 10.8 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2625 zf-Di19 PF05605.7 EDO04093.1 - 0.029 14.4 0.2 0.056 13.5 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3464 PF11947.3 EDO04094.1 - 0.84 9.0 3.0 1.4 8.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF2981 PF11200.3 EDO04098.1 - 0.49 9.4 9.7 0.42 9.6 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) Peptidase_S64 PF08192.6 EDO04098.1 - 0.98 7.6 19.7 1.3 7.2 13.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pol_alpha_B_N PF08418.5 EDO04098.1 - 0.99 8.8 20.0 1.9 7.9 13.9 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Lin-8 PF03353.10 EDO04098.1 - 1 8.5 7.8 1.6 7.9 5.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4022 PF13214.1 EDO04098.1 - 1.1 9.4 5.1 1.2 9.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) CCDC84 PF14968.1 EDO04098.1 - 3.1 7.2 9.6 5.3 6.4 6.6 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DUF966 PF06136.8 EDO04098.1 - 7.6 5.8 20.2 10 5.4 13.7 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Inhibitor_I78 PF11720.3 EDO04100.1 - 7.9e-13 47.9 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EDO04100.1 - 0.00015 21.8 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family PUA PF01472.15 EDO04101.1 - 5e-14 51.7 0.1 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 2 PUA domain 3Beta_HSD PF01073.14 EDO04102.1 - 6.6e-38 130.0 0.2 6.7e-35 120.1 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDO04102.1 - 4.5e-15 55.7 0.4 9.1e-14 51.4 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDO04102.1 - 8.1e-08 31.4 0.2 2.1e-07 30.1 0.1 1.7 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EDO04102.1 - 0.0023 16.8 0.2 0.015 14.2 0.0 2.2 1 1 0 2 2 2 1 RmlD substrate binding domain v110 PF01639.12 EDO04105.1 - 0.16 11.5 1.0 0.2 11.2 0.7 1.1 1 0 0 1 1 1 0 Viral family 110 Rifin_STEVOR PF02009.11 EDO04107.1 - 0.00014 21.6 0.1 0.00019 21.2 0.1 1.1 1 0 0 1 1 1 1 Rifin/stevor family Protocadherin PF08374.6 EDO04107.1 - 0.0026 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Protocadherin DUF912 PF06024.7 EDO04107.1 - 0.03 14.3 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 EDO04107.1 - 0.091 11.0 0.0 0.16 10.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EDO04107.1 - 0.62 9.7 4.1 2.7 7.7 2.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family Plasmodium_Vir PF05795.6 EDO04107.1 - 3.1 6.8 4.6 6.1 5.9 3.2 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein CBFD_NFYB_HMF PF00808.18 EDO04108.1 - 1.3e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO04108.1 - 0.00045 20.2 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 EDO04108.1 - 3.4 6.8 23.3 4.5 6.4 16.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IncA PF04156.9 EDO04110.1 - 0.0041 16.7 2.2 0.0041 16.7 1.6 7.4 4 2 3 7 7 7 2 IncA protein Lip_prot_lig_C PF10437.4 EDO04110.1 - 0.067 12.8 0.4 0.99 9.1 0.0 2.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus S-AdoMet_synt_C PF02773.11 EDO04112.1 - 1.5e-17 63.6 0.0 1.7e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain ATP_bind_1 PF03029.12 EDO04113.1 - 5e-73 245.5 0.0 5.8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDO04113.1 - 3.8e-06 27.7 0.0 1.5e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO04113.1 - 0.00018 21.3 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EDO04113.1 - 0.00044 19.9 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDO04113.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO04113.1 - 0.0033 17.2 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EDO04113.1 - 0.0038 16.8 0.0 0.0092 15.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EDO04113.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EDO04113.1 - 0.005 16.4 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDO04113.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EDO04113.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 EDO04113.1 - 0.0072 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EDO04113.1 - 0.0081 15.6 0.1 0.5 9.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EDO04113.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EDO04113.1 - 0.016 15.2 0.0 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.18 EDO04113.1 - 0.016 14.5 0.0 0.043 13.2 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 EDO04113.1 - 0.032 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_31 PF13614.1 EDO04113.1 - 0.033 14.1 0.0 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO04113.1 - 0.045 14.0 0.1 0.24 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDO04113.1 - 0.079 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EDO04113.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 EDO04113.1 - 0.085 12.5 0.1 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 EDO04113.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 EDO04113.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase SLD3 PF08639.5 EDO04114.1 - 2e-115 386.3 1.2 9.3e-108 361.0 0.0 2.4 1 1 1 2 2 2 2 DNA replication regulator SLD3 Pkinase PF00069.20 EDO04115.1 - 1.8e-68 230.5 0.0 3e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04115.1 - 2.5e-37 128.3 0.0 4.3e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO04115.1 - 1.2e-09 37.5 0.0 2.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO04115.1 - 0.0013 18.5 0.2 0.0086 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDO04115.1 - 0.0086 14.9 0.1 0.025 13.4 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 HABP4_PAI-RBP1 PF04774.10 EDO04117.1 - 0.7 10.4 4.1 0.86 10.1 2.8 1.1 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Ammonium_transp PF00909.16 EDO04118.1 - 1.3e-117 392.6 32.2 1.5e-117 392.4 22.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Collagen PF01391.13 EDO04120.1 - 2.5e-06 26.9 29.3 5.1e-06 25.9 20.3 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Asn_synthase PF00733.16 EDO04121.1 - 5.9e-36 124.2 0.0 7.9e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDO04121.1 - 1.1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDO04121.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDO04121.1 - 0.011 14.8 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 Aluminium induced protein VPS9 PF02204.13 EDO04122.1 - 7.8e-30 102.9 0.1 1.5e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EDO04122.1 - 1.3e-10 40.5 0.1 1.8e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain Fungal_trans PF04082.13 EDO04124.1 - 3.5e-20 71.9 0.0 5.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO04124.1 - 0.00017 21.4 3.4 0.00029 20.6 2.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO04126.1 - 9.2e-16 57.4 0.0 1.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO04126.1 - 0.0016 18.3 2.9 0.0016 18.3 2.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GBP_PSP PF02425.10 EDO04126.1 - 0.46 10.0 6.0 17 5.0 0.6 3.8 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Acetyltransf_7 PF13508.1 EDO04127.1 - 9.3e-09 35.3 0.0 4.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO04127.1 - 1.6e-07 31.4 0.1 2.7e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO04127.1 - 3.7e-05 23.6 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDO04127.1 - 0.00042 20.1 0.0 0.0026 17.6 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO04127.1 - 0.0033 17.5 0.2 0.049 13.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3886 PF13025.1 EDO04127.1 - 0.2 11.6 7.9 0.31 11.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Phage_Gp23 PF10669.4 EDO04127.1 - 0.64 10.1 2.2 1 9.5 1.5 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DNA_pol_B_palm PF14792.1 EDO04129.1 - 3.8e-34 117.0 0.0 7.2e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EDO04129.1 - 1.4e-21 75.9 0.1 4.7e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EDO04129.1 - 6e-19 67.3 0.1 1.2e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EDO04129.1 - 1.2e-11 44.5 0.1 2.5e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.21 EDO04129.1 - 1.9e-06 27.8 0.0 5.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EDO04129.1 - 0.002 18.4 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Trs65 PF12735.2 EDO04132.1 - 1.3e-89 300.6 0.0 1.6e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 EDO04133.1 - 8.7e-55 182.4 8.4 4.7e-16 58.4 0.7 5.7 5 0 0 5 5 5 4 FF domain WW PF00397.21 EDO04133.1 - 2.7e-18 65.4 11.6 1.1e-09 37.9 0.2 2.6 2 0 0 2 2 2 2 WW domain EMP24_GP25L PF01105.19 EDO04133.1 - 0.11 12.2 0.6 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran PF00005.22 EDO04134.1 - 2.7e-34 118.4 0.0 2.7e-16 60.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO04134.1 - 1.3e-13 51.6 6.5 7.1e-05 22.8 0.3 4.8 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EDO04134.1 - 2e-11 43.5 1.2 0.0011 18.2 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDO04134.1 - 4e-07 29.4 0.0 0.59 9.1 0.0 4.1 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.24 EDO04134.1 - 2.2e-05 24.6 0.1 0.019 15.1 0.1 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO04134.1 - 2.9e-05 24.2 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO04134.1 - 2.9e-05 23.2 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Fer4 PF00037.22 EDO04134.1 - 3.9e-05 23.0 3.5 3.9e-05 23.0 2.4 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 EDO04134.1 - 4.1e-05 24.3 0.4 0.39 11.5 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDO04134.1 - 9e-05 21.9 0.4 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO04134.1 - 0.00012 22.4 0.0 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EDO04134.1 - 0.00013 20.7 0.1 0.044 12.4 0.0 3.0 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 EDO04134.1 - 0.00019 21.1 5.0 0.00042 20.0 3.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.1 EDO04134.1 - 0.00043 20.1 0.1 0.066 13.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO04134.1 - 0.00052 19.4 0.1 0.45 9.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EDO04134.1 - 0.00072 19.7 0.2 0.46 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 EDO04134.1 - 0.00073 19.0 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 Virulence-associated protein E UPF0079 PF02367.12 EDO04134.1 - 0.0013 18.3 0.4 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_6 PF12837.2 EDO04134.1 - 0.0014 18.4 2.3 0.0014 18.4 1.6 1.9 2 0 0 2 2 1 1 4Fe-4S binding domain Miro PF08477.8 EDO04134.1 - 0.0021 18.5 0.2 0.31 11.5 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein NACHT PF05729.7 EDO04134.1 - 0.0021 17.7 2.1 0.2 11.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_10 PF13237.1 EDO04134.1 - 0.0026 17.4 4.2 0.0029 17.3 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain MobB PF03205.9 EDO04134.1 - 0.0029 17.2 1.3 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EDO04134.1 - 0.0032 17.7 0.3 2.6 8.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDO04134.1 - 0.0049 16.3 3.1 0.078 12.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RLI PF04068.10 EDO04134.1 - 0.0053 16.3 0.4 0.0053 16.3 0.3 2.2 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_13 PF13166.1 EDO04134.1 - 0.0083 14.6 0.0 0.0083 14.6 0.0 1.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EDO04134.1 - 0.014 15.0 0.3 0.38 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDO04134.1 - 0.014 15.1 0.2 0.81 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EDO04134.1 - 0.015 15.2 0.1 3.6 7.5 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EDO04134.1 - 0.018 13.9 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 EDO04134.1 - 0.022 14.7 4.9 0.07 13.1 3.5 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 EDO04134.1 - 0.026 13.9 0.7 6.5 6.0 0.1 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_16 PF13191.1 EDO04134.1 - 0.028 14.4 0.0 6.1 6.7 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain Fer4_9 PF13187.1 EDO04134.1 - 0.031 14.5 2.0 0.031 14.5 1.4 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 EDO04134.1 - 0.032 14.5 1.6 0.032 14.5 1.1 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EDO04134.1 - 0.036 14.7 2.4 0.04 14.6 0.1 2.2 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_24 PF13479.1 EDO04134.1 - 0.11 12.1 2.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EDO04134.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 EDO04134.1 - 0.14 11.8 2.0 6 6.5 0.1 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EDO04134.1 - 0.15 11.5 0.1 0.15 11.5 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EDO04134.1 - 0.17 11.8 0.1 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EDO04134.1 - 0.17 10.7 0.1 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_15 PF13459.1 EDO04134.1 - 0.27 11.8 1.8 0.71 10.4 0.4 2.4 2 0 0 2 2 1 0 4Fe-4S single cluster domain AAA_14 PF13173.1 EDO04134.1 - 0.42 10.5 3.5 14 5.5 0.0 3.7 4 1 0 4 4 3 0 AAA domain Fer4_17 PF13534.1 EDO04134.1 - 2 8.8 7.0 0.31 11.4 0.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 EDO04134.1 - 3.5 8.4 11.0 0.67 10.6 3.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 EDO04134.1 - 7.1 6.7 9.3 0.21 11.5 1.8 2.0 2 0 0 2 2 1 0 4Fe-4S binding domain SNF2_N PF00176.18 EDO04135.1 - 1.8e-59 201.0 1.9 7.3e-56 189.1 0.3 3.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EDO04135.1 - 1e-20 73.1 4.0 1.7e-13 50.0 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EDO04135.1 - 1.2e-15 57.5 0.0 6.2e-15 55.2 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EDO04135.1 - 5.7e-14 51.7 0.0 1.7e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO04135.1 - 0.042 13.9 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EDO04137.1 - 1.8e-123 412.5 30.5 2e-123 412.3 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO04137.1 - 2.1e-24 85.9 56.4 2.9e-23 82.1 19.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EDO04137.1 - 0.23 10.9 1.7 0.38 10.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) MFS_1_like PF12832.2 EDO04137.1 - 9.2 6.1 12.1 6.3 6.6 0.7 3.5 3 1 0 3 3 3 0 MFS_1 like family SIR2 PF02146.12 EDO04138.1 - 1.6e-08 34.4 0.2 8.7e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Sir2 family zf-C4_ClpX PF06689.8 EDO04138.1 - 0.02 14.4 0.7 0.036 13.5 0.5 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger Med16 PF11635.3 EDO04139.1 - 7.7e-188 625.9 0.0 1e-187 625.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 GST_N_3 PF13417.1 EDO04140.1 - 2.8e-22 78.7 0.0 5.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO04140.1 - 1.7e-13 50.3 0.0 4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDO04140.1 - 3e-05 24.1 0.0 8.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO04140.1 - 0.00067 19.5 0.6 0.0016 18.2 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EDO04140.1 - 0.015 15.2 0.1 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin GST_C PF00043.20 EDO04140.1 - 0.13 12.3 0.0 0.84 9.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FAD_binding_8 PF08022.7 EDO04141.1 - 2.3e-13 49.9 0.0 5.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDO04141.1 - 3.9e-13 49.5 8.8 8.4e-13 48.5 6.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDO04141.1 - 3.2e-08 33.6 0.0 0.00019 21.3 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain DUF4405 PF14358.1 EDO04141.1 - 1.8 8.7 12.7 5.8 7.1 2.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) DDE_1 PF03184.14 EDO04142.1 - 5.5e-34 117.2 0.0 9.9e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GFA PF04828.9 EDO04146.1 - 1.5e-11 44.0 1.6 2.5e-11 43.3 1.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EDO04147.1 - 0.00064 19.5 1.1 0.0014 18.4 0.8 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EDO04147.1 - 0.016 15.2 3.3 1.6 8.8 1.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EDO04147.1 - 0.34 10.9 2.5 1.3 9.0 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EDO04149.1 - 8.6e-117 390.4 0.1 6.2e-116 387.6 0.0 2.1 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EDO04149.1 - 0.016 13.9 0.0 0.067 11.8 0.0 1.9 2 0 0 2 2 2 0 Nitrogen permease regulator 2 Seipin PF06775.9 EDO04151.1 - 3.7e-65 219.1 0.0 4.5e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) UPF0029 PF01205.14 EDO04152.1 - 3e-26 91.2 0.0 8.8e-26 89.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 WD40 PF00400.27 EDO04154.1 - 1.7e-66 217.8 13.0 2.7e-15 55.5 0.0 6.5 5 1 0 5 5 5 5 WD domain, G-beta repeat HET PF06985.6 EDO04154.1 - 1.5e-16 60.8 6.2 7e-15 55.3 4.3 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNase_H PF00075.19 EDO04154.1 - 1.4e-14 54.5 0.0 2.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 RNase H NACHT PF05729.7 EDO04154.1 - 4.4e-08 32.9 0.1 8.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EDO04154.1 - 4e-05 23.1 5.6 11 5.8 0.0 4.5 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 EDO04154.1 - 0.00071 18.6 0.1 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Gmad1 PF10647.4 EDO04154.1 - 0.0049 16.2 0.0 7.2 5.9 0.0 3.7 2 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain zf-RVT PF13966.1 EDO04154.1 - 0.016 15.5 0.0 0.073 13.4 0.0 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF3435 PF11917.3 EDO04155.1 - 1.8e-07 30.2 0.2 2e-07 30.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF2515 PF10720.4 EDO04155.1 - 0.0048 15.8 0.1 0.01 14.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2515) Sfi1 PF08457.5 EDO04155.1 - 0.0076 14.7 0.3 0.0093 14.4 0.2 1.1 1 0 0 1 1 1 1 Sfi1 spindle body protein Moulting_cycle PF04870.11 EDO04155.1 - 0.012 14.6 0.1 0.014 14.5 0.1 1.1 1 0 0 1 1 1 0 Moulting cycle RIO1 PF01163.17 EDO04156.1 - 0.0055 16.0 0.1 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDO04156.1 - 0.043 13.5 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Not1 PF04054.10 EDO04160.1 - 3.1e-129 431.1 0.9 6.3e-129 430.1 0.6 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDO04160.1 - 1.1e-45 154.8 4.7 2.8e-45 153.5 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FCH PF00611.18 EDO04162.1 - 6.2e-22 77.5 0.1 2.2e-21 75.8 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EDO04162.1 - 5.7e-14 51.2 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO04162.1 - 1.1e-11 44.0 0.0 2.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO04162.1 - 4.2e-11 42.1 0.0 1.7e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain NTF2 PF02136.15 EDO04166.1 - 8.7e-30 103.5 0.0 9.7e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3089 PF11288.3 EDO04166.1 - 0.046 12.8 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF4518 PF15008.1 EDO04166.1 - 0.062 12.3 0.1 0.066 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF4440 PF14534.1 EDO04166.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cg6151-P PF10233.4 EDO04167.1 - 2.9e-41 139.9 15.2 3.5e-41 139.7 10.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF3210 PF11489.3 EDO04169.1 - 2.6e-264 879.2 96.8 2.6e-264 879.2 67.1 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3210) Glyco_hydro_65m PF03632.10 EDO04170.1 - 4e-17 61.9 3.4 1.6e-16 59.9 0.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EDO04170.1 - 5.1e-10 39.0 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Ank_2 PF12796.2 EDO04172.1 - 2.5e-12 46.9 0.0 5.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04172.1 - 3.8e-10 39.0 0.6 2.3e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EDO04172.1 - 9.6e-08 32.0 0.2 0.0003 20.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO04172.1 - 4.2e-05 23.3 0.2 0.035 14.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO04172.1 - 0.00048 20.5 0.1 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-primase PF09329.6 EDO04173.1 - 9.6e-18 63.5 1.9 1.7e-17 62.7 1.3 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EDO04173.1 - 0.00077 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 EDO04174.1 - 2.6e-112 374.9 0.2 3.6e-112 374.4 0.2 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) FUSC PF04632.7 EDO04174.1 - 0.078 11.4 0.2 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DASH_Duo1 PF08651.5 EDO04175.1 - 2.8e-31 106.9 0.9 4.1e-31 106.3 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 BRF1 PF07741.8 EDO04175.1 - 1.7 8.9 6.2 1.1 9.5 1.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1682 PF07946.9 EDO04175.1 - 3.4 6.4 7.3 5.9 5.6 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) TTL PF03133.10 EDO04177.1 - 1.1e-49 169.0 0.0 1.7e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EDO04177.1 - 3.7e-44 150.3 0.0 5.6e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EDO04177.1 - 5.9e-05 21.9 0.0 0.0017 17.2 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.1 EDO04177.1 - 0.066 13.3 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain CENP-B_dimeris PF09026.5 EDO04177.1 - 4.8 7.4 13.4 2.5 8.4 3.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HD PF01966.17 EDO04178.1 - 6.5e-07 29.3 0.0 9.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 HD domain MFS_1 PF07690.11 EDO04179.1 - 1.3e-23 83.2 49.2 8.1e-21 74.1 33.3 3.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Metallophos PF00149.23 EDO04180.1 - 6.6e-06 25.6 3.0 2.8e-05 23.5 0.6 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Transp_cyt_pur PF02133.10 EDO04181.1 - 1e-17 63.8 38.9 1.3e-17 63.4 27.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SRR1 PF07985.7 EDO04181.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 SRR1 Methyltransf_18 PF12847.2 EDO04182.1 - 2.7e-15 56.9 0.0 4.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO04182.1 - 5.4e-15 55.3 0.0 9.4e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO04182.1 - 3.4e-13 49.8 0.0 6.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO04182.1 - 2e-12 47.1 0.0 1.1e-11 44.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO04182.1 - 5.3e-12 46.0 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO04182.1 - 1.9e-09 37.8 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO04182.1 - 2.4e-08 34.0 0.0 4.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO04182.1 - 5.7e-08 32.1 0.0 8.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EDO04182.1 - 3.5e-07 29.6 0.0 5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EDO04182.1 - 3.7e-05 23.2 0.0 6.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EDO04182.1 - 5.4e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 EDO04182.1 - 0.00024 20.1 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_9 PF08003.6 EDO04182.1 - 0.00029 19.6 0.0 0.00044 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 EDO04182.1 - 0.00052 19.4 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Bin3 PF06859.7 EDO04182.1 - 0.00093 19.1 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) PCMT PF01135.14 EDO04182.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltrans_SAM PF10672.4 EDO04182.1 - 0.065 12.0 0.0 0.13 11.0 0.0 1.5 1 1 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase UPF0020 PF01170.13 EDO04182.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FUSC_2 PF13515.1 EDO04183.1 - 2.8e-16 59.5 31.0 6.6e-14 51.9 7.2 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 EDO04183.1 - 1.8e-08 33.6 3.1 1.8e-07 30.3 0.9 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 EDO04183.1 - 3.8e-06 25.8 10.3 3.8e-06 25.8 7.1 1.7 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 EDO04183.1 - 0.00013 20.6 17.0 0.00023 19.7 9.0 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF939 PF06081.6 EDO04183.1 - 0.00072 19.4 1.6 0.00072 19.4 1.1 2.5 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF939) SIR2 PF02146.12 EDO04184.1 - 2.9e-56 190.0 0.0 4.3e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EDO04184.1 - 4e-06 26.4 0.1 8.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EDO04184.1 - 0.0013 18.4 0.2 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 EDO04185.1 - 7.8e-60 201.7 1.1 2.8e-59 199.9 0.8 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO04185.1 - 5.5e-42 143.3 10.0 5.5e-42 143.3 7.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO04185.1 - 3.9e-27 96.0 0.0 2.3e-26 93.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO04185.1 - 4.7e-18 64.9 0.0 1.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDO04185.1 - 1.8e-13 51.0 0.0 4e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO04185.1 - 9.8e-06 25.3 1.8 2.7e-05 23.8 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO04185.1 - 1.5e-05 24.3 0.1 9.2e-05 21.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Ribosomal_S11 PF00411.14 EDO04189.1 - 0.4 10.8 3.8 0.36 11.0 1.9 1.5 1 1 0 1 1 1 0 Ribosomal protein S11 NYD-SP12_N PF15015.1 EDO04189.1 - 0.73 7.9 11.6 0.87 7.7 8.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal HC2 PF07382.6 EDO04189.1 - 0.96 9.2 44.6 1.2 8.9 30.9 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 BOP1NT PF08145.7 EDO04191.1 - 5.3e-96 321.3 8.1 7.3e-96 320.8 5.6 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EDO04191.1 - 4.5e-30 102.4 4.1 3.3e-12 45.7 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDO04191.1 - 0.011 14.4 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Pentapeptide_3 PF13576.1 EDO04193.1 - 0.049 13.5 3.1 0.49 10.3 1.8 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EDO04193.1 - 0.18 11.1 0.8 1.4 8.2 0.0 2.8 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) HeLo PF14479.1 EDO04194.1 - 7.5e-40 136.9 0.5 2.1e-39 135.4 0.0 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 EDO04194.1 - 0.071 12.2 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain DUF2057 PF09829.4 EDO04194.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SURF4 PF02077.10 EDO04195.1 - 3.3e-96 321.7 7.4 3.7e-96 321.5 5.1 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 EDO04195.1 - 7 6.8 17.0 1.4 9.0 0.9 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family WH2 PF02205.15 EDO04196.1 - 2e-09 36.7 3.7 2.7e-09 36.3 0.3 2.7 3 0 0 3 3 3 1 WH2 motif Period_C PF12114.3 EDO04199.1 - 0.67 9.5 5.0 0.71 9.4 3.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CHORD PF04968.7 EDO04200.1 - 1.2e-51 172.7 17.9 1.7e-26 92.2 3.8 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EDO04200.1 - 2.8e-13 50.2 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF2360 PF10152.4 EDO04200.1 - 7.1 6.8 6.7 11 6.2 4.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) HpcH_HpaI PF03328.9 EDO04201.1 - 3e-31 108.0 0.0 3.6e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EDO04201.1 - 0.095 11.3 0.1 0.15 10.6 0.1 1.3 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 EDO04202.1 - 0.0025 16.7 0.0 0.0047 15.8 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family SKI PF01202.17 EDO04204.1 - 2.3e-11 43.8 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EDO04204.1 - 1.4e-10 42.0 0.0 1.6e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO04204.1 - 3.4e-10 39.9 0.0 4.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO04204.1 - 5.2e-10 39.7 0.0 8.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO04204.1 - 0.00031 20.8 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDO04204.1 - 0.00034 19.4 0.0 0.0005 18.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EDO04204.1 - 0.00035 20.7 0.0 0.0007 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDO04204.1 - 0.0015 18.4 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO04204.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EDO04204.1 - 0.0029 17.7 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EDO04204.1 - 0.0037 17.1 0.0 0.0088 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO04204.1 - 0.0043 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EDO04204.1 - 0.0054 15.8 0.0 0.0072 15.4 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EDO04204.1 - 0.0057 16.3 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 EDO04204.1 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EDO04204.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EDO04204.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.15 EDO04204.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.1 EDO04204.1 - 0.015 15.2 0.0 0.11 12.3 0.0 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family Mg_chelatase PF01078.16 EDO04204.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EDO04204.1 - 0.029 13.4 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EDO04204.1 - 0.03 13.8 0.1 0.063 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EDO04204.1 - 0.035 13.5 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ArgK PF03308.11 EDO04204.1 - 0.04 12.7 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Arch_ATPase PF01637.13 EDO04204.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EDO04204.1 - 0.047 12.5 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EDO04204.1 - 0.05 13.6 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 EDO04204.1 - 0.067 12.8 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 EDO04204.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EDO04204.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 EDO04204.1 - 0.071 12.6 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MutS_V PF00488.16 EDO04204.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 MutS domain V AAA_25 PF13481.1 EDO04204.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.1 EDO04204.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit 2-oxoacid_dh PF00198.18 EDO04205.1 - 1.5e-69 233.7 0.1 2.1e-69 233.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDO04205.1 - 1.1e-17 63.4 0.0 1.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDO04205.1 - 1.5e-11 43.7 0.1 3.2e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EDO04205.1 - 0.028 14.0 0.1 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-synt_10 PF05176.9 EDO04206.1 - 1.5e-89 299.5 0.0 2.1e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF349 PF03993.7 EDO04207.1 - 0.076 13.1 0.6 0.23 11.6 0.1 2.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) IncA PF04156.9 EDO04207.1 - 0.11 12.0 4.0 0.13 11.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein FliT PF05400.8 EDO04207.1 - 0.36 11.2 6.2 10 6.6 5.4 2.0 1 1 1 2 2 2 0 Flagellar protein FliT Mob1_phocein PF03637.12 EDO04208.1 - 1.2e-37 129.2 2.9 4.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EDO04209.1 - 4.8e-33 114.2 0.1 9.4e-33 113.3 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein tRNA_deacylase PF04414.7 EDO04209.1 - 0.1 11.7 0.0 0.76 8.8 0.0 2.0 1 1 0 1 1 1 0 D-aminoacyl-tRNA deacylase DUF3336 PF11815.3 EDO04210.1 - 1.5e-32 112.0 0.0 6e-32 110.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO04210.1 - 4.4e-16 59.4 0.2 1.2e-15 58.0 0.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Surp PF01805.15 EDO04211.1 - 3.6e-18 64.9 0.1 8.3e-18 63.7 0.0 1.7 2 0 0 2 2 2 1 Surp module DAO PF01266.19 EDO04212.1 - 7.4e-42 143.5 0.0 8.9e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDO04212.1 - 0.00047 19.9 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDO04212.1 - 0.0023 17.9 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO04212.1 - 0.0078 16.1 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO04212.1 - 0.12 11.2 0.0 0.7 8.6 0.0 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A TBP PF00352.16 EDO04213.1 - 1.3e-70 232.7 0.1 1.4e-35 120.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EDO04213.1 - 0.00017 21.5 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EDO04213.1 - 0.11 12.8 3.3 0.17 12.2 2.3 1.4 1 1 0 1 1 1 0 Ribonuclease (pollen allergen) MFS_1 PF07690.11 EDO04215.1 - 6.5e-21 74.4 47.9 9.1e-21 73.9 33.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDO04215.1 - 4.4e-07 28.6 12.6 4.4e-07 28.6 8.8 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Nucleoplasmin PF03066.10 EDO04215.1 - 0.048 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF192 PF02643.10 EDO04216.1 - 0.068 12.8 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 LIM PF00412.17 EDO04217.1 - 6.5e-23 80.5 26.4 1.5e-08 34.5 4.1 3.5 3 0 0 3 3 3 3 LIM domain Choline_kinase PF01633.15 EDO04218.1 - 2.2e-52 177.6 0.0 2e-51 174.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EDO04218.1 - 1.4e-09 38.0 0.2 1.4e-09 38.0 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDO04218.1 - 0.00013 21.1 0.0 0.00038 19.7 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase DUF3425 PF11905.3 EDO04220.1 - 1.4e-19 70.3 0.3 2.9e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDO04220.1 - 7.8e-06 25.7 20.8 5.5e-05 23.0 14.5 2.1 1 1 1 2 2 2 2 bZIP transcription factor HALZ PF02183.13 EDO04220.1 - 0.0034 17.0 0.0 0.0034 17.0 0.0 2.4 2 1 0 2 2 2 1 Homeobox associated leucine zipper FANCI_S3 PF14677.1 EDO04220.1 - 0.084 12.2 0.1 4 6.7 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 3 bZIP_Maf PF03131.12 EDO04220.1 - 0.1 12.9 15.4 0.19 12.0 10.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2937 PF11157.3 EDO04220.1 - 0.12 11.7 1.3 0.21 10.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DivIC PF04977.10 EDO04220.1 - 0.25 10.8 6.8 0.14 11.6 3.0 1.8 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 EDO04220.1 - 0.35 10.7 25.4 1 9.2 4.7 2.5 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EDO04220.1 - 1.4 8.9 5.1 2.3 8.2 2.7 2.0 2 1 0 2 2 2 0 TSC-22/dip/bun family Spt5_N PF11942.3 EDO04220.1 - 1.5 9.4 11.8 2.6 8.7 8.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal IncA PF04156.9 EDO04220.1 - 4.6 6.8 7.9 8.7 5.8 5.4 1.4 1 0 0 1 1 1 0 IncA protein CorA PF01544.13 EDO04225.1 - 1.8e-07 30.4 0.5 3.6e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SieB PF14163.1 EDO04225.1 - 0.00043 19.8 1.0 0.0009 18.8 0.7 1.5 1 0 0 1 1 1 1 Superinfection exclusion protein B Acetyltransf_1 PF00583.19 EDO04226.1 - 2.2e-13 50.0 0.1 4.4e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO04226.1 - 1.1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO04226.1 - 9.6e-09 35.3 0.1 4.7e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO04226.1 - 2.8e-05 24.2 0.0 3.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO04226.1 - 6.5e-05 22.8 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO04226.1 - 7.6e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EDO04226.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase AAA_2 PF07724.9 EDO04227.1 - 8.7e-45 152.6 0.0 2.9e-43 147.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EDO04227.1 - 8.5e-26 89.6 0.4 2.8e-25 88.0 0.3 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EDO04227.1 - 2.6e-19 69.7 0.0 2.7e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO04227.1 - 1.1e-13 51.0 0.0 2.4e-08 33.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO04227.1 - 5.1e-10 39.6 0.0 0.0018 18.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EDO04227.1 - 3.1e-08 33.2 0.2 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 EDO04227.1 - 6e-08 32.8 11.5 0.0024 17.9 0.0 4.9 4 2 1 6 6 5 2 AAA ATPase domain Arch_ATPase PF01637.13 EDO04227.1 - 1e-06 28.6 7.2 0.083 12.5 0.1 4.8 3 2 0 3 3 3 2 Archaeal ATPase AAA_14 PF13173.1 EDO04227.1 - 5.9e-06 26.1 0.0 0.096 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDO04227.1 - 8.8e-06 25.4 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EDO04227.1 - 8.1e-05 22.3 0.0 0.034 13.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EDO04227.1 - 0.00015 21.2 0.0 0.21 10.9 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDO04227.1 - 0.00025 20.7 0.0 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EDO04227.1 - 0.00054 20.7 7.0 0.086 13.6 0.1 3.8 3 2 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EDO04227.1 - 0.0011 19.0 0.0 0.5 10.5 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EDO04227.1 - 0.0016 18.3 3.3 0.27 11.1 0.0 4.0 4 1 0 4 4 3 1 AAA domain SRP54 PF00448.17 EDO04227.1 - 0.0017 17.8 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EDO04227.1 - 0.0025 16.5 0.0 0.35 9.4 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EDO04227.1 - 0.0027 16.8 0.4 5.1 6.1 0.0 3.6 2 2 1 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDO04227.1 - 0.0035 17.6 9.1 0.96 9.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain ABC_tran PF00005.22 EDO04227.1 - 0.0037 17.5 1.9 1.3 9.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.1 EDO04227.1 - 0.0079 15.7 0.4 0.33 10.4 0.0 3.2 3 1 1 4 4 3 1 AAA domain Zeta_toxin PF06414.7 EDO04227.1 - 0.0085 15.2 0.0 0.54 9.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin UvrD-helicase PF00580.16 EDO04227.1 - 0.0098 15.2 1.7 0.19 10.9 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_33 PF13671.1 EDO04227.1 - 0.012 15.4 0.1 6.6 6.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EDO04227.1 - 0.013 14.8 0.4 4 6.7 0.0 3.4 2 2 1 3 3 3 0 AAA domain DUF258 PF03193.11 EDO04227.1 - 0.015 14.4 0.1 6.6 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EDO04227.1 - 0.016 15.6 0.0 0.86 10.1 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EDO04227.1 - 0.019 14.4 0.3 0.21 10.9 0.1 2.8 2 2 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 EDO04227.1 - 0.023 13.6 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.10 EDO04227.1 - 0.023 14.5 2.6 3.5 7.4 0.0 3.4 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 EDO04227.1 - 0.025 14.1 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EDO04227.1 - 0.033 13.8 0.0 15 5.2 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EDO04227.1 - 0.035 13.6 0.0 2.5 7.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EDO04227.1 - 0.036 13.2 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_15 PF13175.1 EDO04227.1 - 0.037 13.0 3.0 0.094 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 EDO04227.1 - 0.046 13.3 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDO04227.1 - 0.059 12.8 0.4 18 4.7 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EDO04227.1 - 0.11 11.9 0.0 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain V_ATPase_I PF01496.14 EDO04227.1 - 0.13 10.0 3.5 0.19 9.5 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EDO04227.1 - 0.24 11.0 12.1 0.42 10.2 8.4 1.3 1 0 0 1 1 1 0 Mnd1 family DUF2664 PF10867.3 EDO04227.1 - 0.66 10.6 5.3 8.6 7.0 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2664) DUF87 PF01935.12 EDO04227.1 - 0.97 9.1 5.1 27 4.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 Atg14 PF10186.4 EDO04227.1 - 1.3 7.8 8.4 3.2 6.6 5.8 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EDO04227.1 - 3.3 7.2 15.3 7.7 6.0 10.6 1.6 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EDO04227.1 - 3.4 7.0 8.1 7.5 5.8 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 EDO04227.1 - 4.4 6.2 11.3 7.4 5.5 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EDO04227.1 - 5.1 6.6 12.0 9.3 5.8 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EF1_GNE PF00736.14 EDO04228.1 - 8.9e-30 102.2 2.1 1.7e-29 101.3 1.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDO04228.1 - 1.6e-14 53.7 7.5 1.6e-14 53.7 5.2 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EDO04228.1 - 0.00016 22.0 0.2 0.00043 20.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDO04228.1 - 0.0015 18.5 0.2 0.0042 17.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MutS_V PF00488.16 EDO04229.1 - 6.2e-53 179.6 0.0 1.2e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO04229.1 - 5.6e-23 81.8 0.0 2.5e-22 79.7 0.0 2.1 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EDO04229.1 - 0.017 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV Coq4 PF05019.8 EDO04229.1 - 0.018 13.9 0.3 0.058 12.2 0.0 1.9 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ABC2_membrane PF01061.19 EDO04232.1 - 2.7e-93 310.9 46.3 2.3e-50 170.6 7.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EDO04232.1 - 9.8e-38 129.5 0.1 5.1e-19 68.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EDO04232.1 - 5.2e-34 116.0 4.2 6.8e-30 102.7 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EDO04232.1 - 2.9e-07 30.4 0.1 8.1e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EDO04232.1 - 4.8e-06 25.8 8.1 4.8e-06 25.8 5.6 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.14 EDO04232.1 - 8.5e-06 25.3 0.0 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EDO04232.1 - 3.8e-05 23.7 0.1 0.15 11.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDO04232.1 - 3.9e-05 23.8 0.0 0.078 13.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EDO04232.1 - 4.3e-05 22.7 0.0 0.0006 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EDO04232.1 - 4.5e-05 23.3 0.0 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO04232.1 - 5e-05 22.7 0.3 0.19 11.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDO04232.1 - 9e-05 22.4 0.0 0.074 13.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDO04232.1 - 9.3e-05 22.7 0.1 0.037 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EDO04232.1 - 0.00015 21.0 0.9 0.13 11.4 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EDO04232.1 - 0.00028 20.8 0.1 0.0053 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO04232.1 - 0.0003 21.5 0.0 0.18 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDO04232.1 - 0.00075 19.0 0.1 0.92 8.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EDO04232.1 - 0.0018 18.2 2.6 0.027 14.4 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.7 EDO04232.1 - 0.0042 16.7 0.5 0.23 11.0 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EDO04232.1 - 0.0044 16.4 0.0 0.67 9.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EDO04232.1 - 0.0066 16.0 0.5 0.18 11.4 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EDO04232.1 - 0.031 13.9 0.0 9.8 5.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 EDO04232.1 - 0.034 13.0 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EDO04232.1 - 0.035 12.9 0.9 2.8 6.7 0.2 2.9 3 0 0 3 3 3 0 NB-ARC domain Septin PF00735.13 EDO04232.1 - 0.056 12.4 0.1 0.35 9.8 0.1 2.1 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EDO04232.1 - 0.086 12.3 0.4 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDO04232.1 - 0.13 12.8 0.0 2.5 8.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EDO04232.1 - 0.18 11.3 1.1 0.41 10.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDO04232.1 - 0.36 10.3 8.5 1.8 8.1 0.3 4.0 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 EDO04232.1 - 0.47 9.8 3.3 6.9 6.0 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain DUF3405 PF11885.3 EDO04233.1 - 3.1e-214 711.8 3.2 3.5e-214 711.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) YHS PF04945.8 EDO04233.1 - 0.069 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 YHS domain Bactofilin PF04519.8 EDO04238.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.7 1 1 0 1 1 1 0 Polymer-forming cytoskeletal Zn_clus PF00172.13 EDO04239.1 - 8.4e-09 35.2 11.0 1.4e-08 34.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CwfJ_C_1 PF04677.10 EDO04241.1 - 1.8e-31 108.3 0.0 2.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDO04241.1 - 1.5e-24 86.3 0.0 5.2e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EDO04242.1 - 1.5e-73 247.2 0.0 2e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EDO04242.1 - 0.00029 20.3 0.0 0.0039 16.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EDO04242.1 - 0.00093 18.0 0.0 0.015 14.0 0.0 2.3 2 0 0 2 2 2 1 ArgK protein PRK PF00485.13 EDO04242.1 - 0.0019 17.8 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 EDO04242.1 - 0.0037 17.7 0.0 0.066 13.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EDO04242.1 - 0.048 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 EDO04242.1 - 0.057 14.2 0.0 0.5 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDO04242.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EDO04242.1 - 0.56 10.5 2.9 8.5 6.6 2.0 2.1 1 1 0 1 1 1 0 AAA domain DNA_RNApol_7kD PF03604.8 EDO04243.1 - 2.2e-17 62.1 4.0 2.9e-17 61.8 2.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF951 PF06107.6 EDO04243.1 - 0.0016 17.9 0.4 1 8.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF951) A2L_zn_ribbon PF08792.5 EDO04243.1 - 0.0063 15.9 0.7 0.65 9.5 0.0 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain DZR PF12773.2 EDO04243.1 - 0.018 14.8 0.2 0.025 14.3 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EDO04243.1 - 0.038 13.9 0.5 0.063 13.2 0.3 1.3 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 EDO04243.1 - 0.058 13.0 0.1 0.074 12.7 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_ribbon_recom PF13408.1 EDO04243.1 - 0.1 12.8 0.8 3.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain SLAIN PF15301.1 EDO04244.1 - 0.0061 15.7 3.6 0.0087 15.2 2.5 1.2 1 0 0 1 1 1 1 SLAIN motif-containing family ubiquitin PF00240.18 EDO04244.1 - 0.0086 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO04244.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MFS_1 PF07690.11 EDO04245.1 - 5.7e-05 22.0 0.4 5.7e-05 22.0 0.3 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily EMP24_GP25L PF01105.19 EDO04246.1 - 1.8e-47 161.4 0.0 2.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.16 EDO04247.1 - 3.5e-79 264.0 0.2 4.1e-79 263.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO04247.1 - 1.1e-14 54.0 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO04247.1 - 2.5e-13 49.7 0.0 2.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDO04247.1 - 1.1e-12 47.3 1.7 1.2e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO04247.1 - 3.8e-11 42.5 0.0 4.4e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO04247.1 - 1.5e-08 35.1 0.0 2.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO04247.1 - 3.3e-06 27.0 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO04247.1 - 0.0062 15.9 0.1 0.041 13.2 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EDO04247.1 - 0.0081 15.2 0.4 0.017 14.2 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EDO04247.1 - 0.042 13.7 0.2 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.14 EDO04248.1 - 1.2e-51 174.3 0.0 1.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EDO04248.1 - 0.00049 19.9 0.1 0.00086 19.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_3 PF00591.16 EDO04249.1 - 5.7e-62 209.3 0.0 8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EDO04249.1 - 3.9e-14 51.9 0.0 8.8e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Lip_A_acyltrans PF03279.8 EDO04249.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Ribosomal_L10 PF00466.15 EDO04250.1 - 0.024 14.5 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L10 SCP1201-deam PF14428.1 EDO04250.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 SCP1.201-like deaminase PI-PLC-X PF00388.14 EDO04251.1 - 1.6e-14 53.5 0.0 2.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3596 PF12167.3 EDO04251.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) NS3_envE PF02723.9 EDO04252.1 - 1.5 8.7 13.9 0.081 12.8 4.2 2.1 1 1 1 2 2 2 0 Non-structural protein NS3/Small envelope protein E RRM_1 PF00076.17 EDO04254.1 - 7e-16 57.6 0.3 1.1e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO04254.1 - 2.5e-12 46.6 0.1 9.9e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO04254.1 - 1.1e-05 25.1 0.0 2.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO04254.1 - 0.038 13.8 6.2 0.11 12.3 0.3 3.3 3 0 0 3 3 3 0 RNA binding motif ERG2_Sigma1R PF04622.7 EDO04255.1 - 9.1e-91 302.9 0.9 1e-90 302.7 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Nefa_Nip30_N PF10187.4 EDO04256.1 - 1e-27 96.2 6.3 1e-27 96.2 4.3 2.5 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pyocin_S PF06958.7 EDO04256.1 - 4.7 7.5 8.6 10 6.4 5.9 1.6 1 1 0 1 1 1 0 S-type Pyocin Aldo_ket_red PF00248.16 EDO04257.1 - 1.7e-48 164.8 0.0 2e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.18 EDO04258.1 - 1.7e-19 70.1 0.0 2.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDO04258.1 - 1.1e-06 28.8 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDO04258.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CAP PF00188.21 EDO04259.1 - 2.5e-17 63.5 4.9 3.3e-17 63.1 3.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family tRNA_lig_CPD PF08302.6 EDO04260.1 - 3e-86 288.7 0.0 4.2e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EDO04260.1 - 1e-80 270.3 0.1 3e-80 268.8 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EDO04260.1 - 1.8e-54 184.0 0.0 3.3e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EDO04260.1 - 0.021 15.6 0.1 0.19 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EDO04260.1 - 0.053 13.8 0.3 0.47 10.7 0.0 2.6 3 0 0 3 3 3 0 ABC transporter Ank_5 PF13857.1 EDO04261.1 - 6.6e-11 42.0 0.9 4.2e-10 39.5 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO04261.1 - 6.9e-06 26.4 0.1 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO04261.1 - 9.4e-05 22.6 0.9 0.00099 19.4 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDO04261.1 - 0.0019 18.2 0.5 0.016 15.4 0.2 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EDO04261.1 - 0.0022 17.7 1.0 0.014 15.2 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat UPF0020 PF01170.13 EDO04263.1 - 3.1e-11 43.1 0.0 5.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDO04263.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aldo_ket_red PF00248.16 EDO04265.1 - 2.8e-54 183.8 0.0 3.3e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Polysacc_deac_1 PF01522.16 EDO04266.1 - 1.8e-27 95.4 0.0 2.9e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EDO04266.1 - 3e-06 27.1 29.7 0.0026 17.7 6.0 3.5 3 0 0 3 3 3 2 Chitin recognition protein CK_II_beta PF01214.13 EDO04267.1 - 1.3e-70 236.6 1.1 2e-70 236.0 0.8 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Myc_N PF01056.13 EDO04267.1 - 1.5 7.9 4.3 2.3 7.3 3.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sugar_tr PF00083.19 EDO04268.1 - 8.1e-13 47.7 13.1 5.1e-11 41.8 9.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO04268.1 - 7.1e-11 41.4 24.2 1e-08 34.2 8.3 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1228 PF06779.9 EDO04268.1 - 0.031 14.2 1.4 11 6.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Cyclin_N PF00134.18 EDO04269.1 - 1.3e-45 154.0 1.5 2.2e-44 150.0 0.1 2.8 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO04269.1 - 2.2e-36 124.3 0.2 6.9e-36 122.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EDO04270.1 - 7.2e-46 155.2 1.6 1.7e-45 154.0 1.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO04270.1 - 1.3e-26 92.3 0.6 2.5e-26 91.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fungal_trans PF04082.13 EDO04271.1 - 2.5e-17 62.5 1.4 9.1e-17 60.7 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO04271.1 - 1.5e-09 37.6 9.6 2.5e-09 36.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4634 PF15465.1 EDO04272.1 - 0.096 12.8 0.0 0.096 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) WD40 PF00400.27 EDO04273.1 - 3.9e-31 105.7 8.7 1.3e-08 34.3 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EDO04273.1 - 7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 EDO04273.1 - 0.001 17.3 0.6 0.058 11.5 0.0 2.9 2 1 0 3 3 3 1 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EDO04273.1 - 0.0055 16.4 0.5 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term eIF2A PF08662.6 EDO04273.1 - 0.012 15.2 0.1 2.7 7.6 0.0 3.2 1 1 3 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EDO04273.1 - 0.033 13.0 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Apc4_WD40 PF12894.2 EDO04273.1 - 0.05 13.1 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EDO04273.1 - 0.14 11.8 1.5 9.2 6.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RIC1 PF07064.8 EDO04274.1 - 4.9e-93 311.2 0.1 6.8e-93 310.8 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EDO04274.1 - 0.00047 19.9 1.8 9.4 6.2 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat V-ATPase_H_N PF03224.9 EDO04275.1 - 1.4e-78 264.2 0.0 2.3e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EDO04275.1 - 8.5e-40 135.3 0.1 3e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H DUF619 PF04768.8 EDO04275.1 - 0.043 13.2 0.0 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF619) GCV_T PF01571.16 EDO04276.1 - 3.9e-63 212.6 0.0 5.1e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDO04276.1 - 1.5e-23 82.6 0.6 3e-23 81.6 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain YpzI PF14140.1 EDO04277.1 - 0.0044 16.4 1.7 0.0044 16.4 1.1 1.4 1 1 0 1 1 1 1 YpzI-like protein Aa_trans PF01490.13 EDO04279.1 - 1.3e-33 116.0 37.0 1.6e-33 115.7 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2561 PF10812.3 EDO04279.1 - 0.15 11.5 0.1 0.15 11.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2561) AA_permease_2 PF13520.1 EDO04279.1 - 0.18 10.2 50.2 41 2.5 34.8 2.2 1 1 0 1 1 1 0 Amino acid permease Hydrophobin_2 PF06766.6 EDO04280.1 - 0.0035 16.9 6.5 0.014 15.0 4.5 2.0 1 1 0 1 1 1 1 Fungal hydrophobin Ish1 PF10281.4 EDO04282.1 - 2.3e-90 296.1 28.3 1.5e-15 56.8 0.0 8.6 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EDO04282.1 - 3.9e-14 51.9 2.3 0.018 14.5 0.0 7.2 8 0 0 8 8 8 3 HeH/LEM domain SAP PF02037.22 EDO04282.1 - 5.3e-08 32.1 0.0 1.5 8.4 0.0 6.1 5 2 0 5 5 5 3 SAP domain Slx4 PF09494.5 EDO04282.1 - 1.5e-07 31.0 0.6 2.2 8.0 0.0 5.7 5 1 0 5 5 5 2 Slx4 endonuclease APC2 PF08672.6 EDO04282.1 - 0.00067 19.8 1.8 25 5.2 0.0 5.6 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 EDO04282.1 - 0.012 14.9 0.0 2.6 7.5 0.0 3.6 3 0 0 3 3 3 0 LEM domain SAM_2 PF07647.12 EDO04282.1 - 0.031 14.0 2.6 10 6.0 0.0 4.9 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) SAP30_Sin3_bdg PF13867.1 EDO04282.1 - 0.056 13.3 2.1 5.7 6.8 0.0 4.5 6 0 0 6 6 6 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Thioredoxin_6 PF13848.1 EDO04282.1 - 0.12 12.2 0.0 18 5.0 0.0 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain DUF2795 PF11387.3 EDO04282.1 - 4.9 7.1 9.0 5.1 7.0 0.1 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2795) Kelch_5 PF13854.1 EDO04283.1 - 4.5e-11 42.4 17.6 2.6e-08 33.6 0.3 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EDO04283.1 - 2.4e-10 40.0 16.2 0.00012 21.7 0.6 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO04283.1 - 2e-07 30.9 18.7 2.4e-05 24.3 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO04283.1 - 7.1e-05 22.8 20.7 0.00058 19.9 0.5 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EDO04283.1 - 0.00013 21.6 7.6 0.0043 16.7 0.2 3.5 3 0 0 3 3 3 2 Kelch motif EVI2A PF05399.6 EDO04283.1 - 0.0015 17.8 0.4 0.0025 17.1 0.2 1.3 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) Kelch_1 PF01344.20 EDO04283.1 - 1.1 8.9 14.2 0.14 11.7 0.3 4.2 4 0 0 4 4 4 0 Kelch motif Serglycin PF04360.7 EDO04283.1 - 5.2 6.7 13.4 0.48 10.1 5.7 2.0 2 0 0 2 2 2 0 Serglycin G0-G1_switch_2 PF15103.1 EDO04286.1 - 0.99 9.6 3.2 0.66 10.2 0.1 2.3 3 0 0 3 3 3 0 G0/G1 switch protein 2 Mem_trans PF03547.13 EDO04291.1 - 0.00011 20.6 0.0 0.00012 20.4 0.0 1.0 1 0 0 1 1 1 1 Membrane transport protein Mem_trans PF03547.13 EDO04292.1 - 1.8e-14 52.8 0.0 2.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein CDC45 PF02724.9 EDO04292.1 - 0.005 14.9 1.1 0.0086 14.1 0.8 1.3 1 0 0 1 1 1 1 CDC45-like protein Upf2 PF04050.9 EDO04292.1 - 0.014 15.1 1.7 0.021 14.5 1.2 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Cut8_N PF14482.1 EDO04292.1 - 0.28 11.2 3.2 0.68 9.9 2.2 1.7 1 1 0 1 1 1 0 Cut8 proteasome-binding domain CPL PF08144.6 EDO04293.1 - 4.7e-18 65.4 3.1 1.6e-17 63.7 0.0 3.5 4 2 1 5 5 5 1 CPL (NUC119) domain RWD PF05773.17 EDO04294.1 - 1.2e-22 79.9 0.4 1.2e-22 79.9 0.2 1.9 2 1 0 2 2 2 1 RWD domain UQ_con PF00179.21 EDO04294.1 - 0.26 10.7 1.5 0.37 10.2 0.4 1.7 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Potyvirid-P3 PF13608.1 EDO04294.1 - 0.28 10.2 5.3 0.37 9.8 3.7 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein TPR_12 PF13424.1 EDO04295.1 - 7.2e-08 32.2 0.5 0.00013 21.8 0.0 4.0 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO04295.1 - 6.7e-07 28.8 0.9 0.0056 16.3 0.0 3.9 4 1 1 5 5 5 3 TPR repeat TPR_19 PF14559.1 EDO04295.1 - 1.1e-06 28.9 1.2 0.13 12.5 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04295.1 - 2.7e-06 26.8 0.0 0.032 14.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO04295.1 - 5.9e-06 26.8 0.2 0.011 16.4 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04295.1 - 1.9e-05 24.8 1.1 1.3 9.8 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04295.1 - 6.4e-05 22.4 0.1 0.13 12.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04295.1 - 0.00021 20.8 0.0 0.0042 16.7 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04295.1 - 0.0025 17.8 0.0 6.6 7.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04295.1 - 0.0037 16.8 0.0 0.29 10.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO04295.1 - 0.057 13.9 0.1 45 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO04295.1 - 0.24 11.3 3.1 4.8 7.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Rad51 PF08423.6 EDO04299.1 - 1.8e-139 462.8 0.0 2.2e-139 462.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO04299.1 - 1.1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDO04299.1 - 6.3e-08 32.0 0.0 8.5e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EDO04299.1 - 8.1e-07 29.1 0.1 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EDO04299.1 - 5.9e-06 25.5 0.1 1.2e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EDO04299.1 - 0.036 12.9 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Nup160 PF11715.3 EDO04300.1 - 8.2e-163 542.4 0.0 1.2e-162 541.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.10 EDO04301.1 - 3e-126 419.8 0.6 3.5e-126 419.5 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EDO04301.1 - 5.9e-05 22.9 0.1 3.8 7.3 0.0 3.7 3 1 1 4 4 4 3 Arrestin (or S-antigen), N-terminal domain LSM PF01423.17 EDO04302.1 - 2.8e-17 62.0 0.0 3.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain Gemin6 PF06372.7 EDO04302.1 - 0.059 12.6 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein IU_nuc_hydro PF01156.14 EDO04303.1 - 5.9e-58 196.5 0.5 2.6e-47 161.5 0.2 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Acetate_kinase PF00871.12 EDO04306.1 - 3.4e-86 289.2 0.1 6.4e-66 222.4 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family XFP_N PF09364.5 EDO04307.1 - 6e-138 459.5 0.0 1e-137 458.7 0.0 1.4 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EDO04307.1 - 7.4e-67 224.3 0.0 1.1e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EDO04307.1 - 5.3e-66 221.9 0.0 1.2e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EDO04307.1 - 0.00075 19.0 0.2 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zf-C2H2_4 PF13894.1 EDO04309.1 - 1.1e-05 25.4 8.2 0.003 17.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO04309.1 - 0.0016 18.6 15.3 0.015 15.6 0.3 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO04309.1 - 0.016 15.4 11.6 0.02 15.1 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EDO04309.1 - 0.019 15.1 3.6 1.2 9.4 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type HET PF06985.6 EDO04312.1 - 8.5e-25 87.5 0.1 2.3e-24 86.1 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Prp31_C PF09785.4 EDO04313.1 - 2.2e-42 144.3 2.7 3.3e-42 143.8 0.7 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EDO04313.1 - 8.2e-41 138.7 0.0 1.4e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO04313.1 - 6e-22 77.2 0.1 1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain TPR_16 PF13432.1 EDO04314.1 - 3.5e-21 75.3 1.3 0.00029 21.4 0.0 6.8 6 1 0 7 7 7 4 Tetratricopeptide repeat HAT PF02184.11 EDO04314.1 - 1.8e-20 72.3 61.5 9.1e-15 54.1 2.1 10.8 11 1 0 11 11 11 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EDO04314.1 - 2.2e-20 71.2 13.4 0.0004 20.7 0.0 8.7 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04314.1 - 2.4e-19 69.4 0.2 2.4e-05 24.6 0.0 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04314.1 - 8.9e-12 43.9 8.2 0.081 12.8 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO04314.1 - 3.5e-08 32.9 2.0 0.24 11.0 0.0 4.5 4 0 0 4 4 4 3 TPR repeat Suf PF05843.9 EDO04314.1 - 2e-07 31.0 14.0 0.0045 16.7 0.8 4.3 1 1 4 5 5 5 2 Suppressor of forked protein (Suf) TPR_7 PF13176.1 EDO04314.1 - 5.9e-07 28.8 4.2 4.8 7.2 0.2 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04314.1 - 6.7e-06 25.9 14.2 1.2 9.1 0.0 6.3 6 1 0 6 6 6 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EDO04314.1 - 7.6e-05 22.3 15.7 0.039 13.7 1.0 4.8 3 1 1 4 4 4 2 U3 small nucleolar RNA-associated protein 6 TPR_15 PF13429.1 EDO04314.1 - 8.6e-05 21.7 14.3 0.21 10.6 0.6 4.4 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04314.1 - 9.1e-05 22.3 2.4 0.069 13.3 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO04314.1 - 0.00023 21.3 10.5 22 5.7 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO04314.1 - 0.0064 16.5 5.1 1.2 9.2 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EDO04314.1 - 0.011 15.3 4.6 16 5.3 0.0 4.9 7 0 0 7 7 6 0 Tetratricopeptide repeat B12-binding_2 PF02607.12 EDO04314.1 - 0.04 13.9 0.2 9.4 6.3 0.0 3.8 4 0 0 4 4 4 0 B12 binding domain NRDE-2 PF08424.5 EDO04314.1 - 0.056 12.3 20.7 0.056 12.3 0.1 4.9 2 2 2 5 5 5 0 NRDE-2, necessary for RNA interference Fis1_TPR_C PF14853.1 EDO04314.1 - 0.084 12.7 4.1 15 5.5 0.4 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EDO04314.1 - 3 7.7 7.1 18 5.2 0.2 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EDO04314.1 - 3.7 7.7 7.4 5.4 7.2 0.0 3.6 3 1 1 4 4 3 0 c-SKI Smad4 binding domain Suf PF05843.9 EDO04315.1 - 0.02 14.6 0.6 0.027 14.1 0.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PaaSYMP PF14738.1 EDO04315.1 - 0.03 14.0 3.9 0.034 13.8 2.3 1.4 1 1 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Cut8_N PF14482.1 EDO04315.1 - 0.046 13.7 5.4 0.7 9.9 0.4 2.3 2 0 0 2 2 2 0 Cut8 proteasome-binding domain WIYLD PF10440.4 EDO04315.1 - 0.14 12.1 1.2 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain PBP1_TM PF14812.1 EDO04315.1 - 0.26 11.5 14.8 0.34 11.2 1.2 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BEX PF04538.7 EDO04315.1 - 0.47 10.7 7.1 0.57 10.4 4.9 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family SPT6_acidic PF14632.1 EDO04315.1 - 8.4 6.6 19.6 4.5 7.5 6.3 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Pkinase PF00069.20 EDO04316.1 - 5.1e-14 52.0 0.0 4.9e-13 48.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04316.1 - 0.037 13.1 0.0 0.35 9.8 0.0 2.3 2 1 0 2 2 2 0 Protein tyrosine kinase Spt5_N PF11942.3 EDO04316.1 - 1.8 9.2 20.8 3.1 8.4 0.6 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal HET PF06985.6 EDO04317.1 - 9.7e-30 103.5 0.6 1.7e-29 102.7 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PCI_Csn8 PF10075.4 EDO04321.1 - 4.3e-06 26.5 0.0 6.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDO04321.1 - 2.7e-05 23.8 0.0 6.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HlyIII PF03006.15 EDO04322.1 - 2.1e-53 181.0 13.4 2.5e-53 180.7 9.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EDO04322.1 - 0.087 12.7 0.3 0.087 12.7 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4149 PF13664.1 EDO04322.1 - 0.28 11.2 8.3 4.1 7.5 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF3325 PF11804.3 EDO04322.1 - 2.1 8.2 6.6 0.25 11.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) adh_short PF00106.20 EDO04323.1 - 1.4e-31 109.7 0.2 2.1e-31 109.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO04323.1 - 1.2e-26 94.0 0.5 1.9e-26 93.3 0.4 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO04323.1 - 5.2e-16 58.8 0.1 7.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EDO04323.1 - 0.0048 16.5 0.4 0.0076 15.9 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EDO04323.1 - 0.013 15.3 0.3 0.021 14.6 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NIR_SIR_ferr PF03460.12 EDO04323.1 - 0.058 13.0 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain UDPG_MGDP_dh_N PF03721.9 EDO04323.1 - 0.099 12.0 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.21 EDO04324.1 - 2.9e-28 98.6 0.0 3.7e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDO04324.1 - 4.6e-10 39.6 0.0 1.4e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EDO04324.1 - 8.5e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDO04324.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 GMC_oxred_C PF05199.8 EDO04325.1 - 2.2e-37 128.5 0.0 4.5e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EDO04325.1 - 5.4e-24 84.8 0.0 7.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase SET PF00856.23 EDO04326.1 - 3.8e-05 24.0 0.0 6.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Cyt-b5 PF00173.23 EDO04329.1 - 4.3e-13 48.8 0.0 5.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 4HBT PF03061.17 EDO04331.1 - 9.3e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EDO04331.1 - 0.0046 16.9 0.0 0.0063 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Macoilin PF09726.4 EDO04334.1 - 9.8 4.3 20.4 12 3.9 14.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Vps35 PF03635.12 EDO04335.1 - 0 1024.7 6.7 0 1024.5 4.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.16 EDO04335.1 - 0.04 13.6 1.3 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Endoribonuclease L-PSP TFR_dimer PF04253.10 EDO04336.1 - 1.2e-20 73.3 0.0 2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EDO04336.1 - 0.0006 19.4 0.0 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.12 EDO04336.1 - 0.012 15.3 0.1 0.57 9.8 0.0 2.3 1 1 1 2 2 2 0 Peptidase family M28 PhoD PF09423.5 EDO04339.1 - 3e-09 35.9 0.1 7.3e-08 31.4 0.0 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase ASFV_J13L PF05568.6 EDO04340.1 - 2.9 7.4 8.1 4 6.9 5.6 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Rhomboid PF01694.17 EDO04341.1 - 3.9e-19 69.1 5.0 3.9e-19 69.1 3.5 1.6 2 0 0 2 2 2 1 Rhomboid family DUF3638 PF12340.3 EDO04343.1 - 8.2e-102 339.0 0.1 1.4e-101 338.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EDO04343.1 - 2.3e-15 55.4 0.0 4.9e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF1788 PF08747.6 EDO04343.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) AA_permease_2 PF13520.1 EDO04347.1 - 3.4e-54 184.0 54.0 4.2e-54 183.6 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO04347.1 - 3.3e-37 127.9 47.0 4.5e-37 127.5 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EDO04348.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO04348.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO04348.1 - 0.00033 20.4 0.0 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO04348.1 - 0.031 14.4 0.0 0.051 13.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PLDc_N PF13396.1 EDO04351.1 - 2.3e-12 46.3 5.4 2.3e-12 46.3 3.7 1.7 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF3309 PF11752.3 EDO04351.1 - 0.022 14.5 1.6 0.022 14.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Pox_A14 PF05767.7 EDO04351.1 - 0.035 14.0 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MARVEL PF01284.18 EDO04351.1 - 0.18 11.5 6.0 0.32 10.8 4.2 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF4199 PF13858.1 EDO04351.1 - 0.25 11.2 4.1 0.083 12.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF3951 PF13131.1 EDO04351.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF3671 PF12420.3 EDO04351.1 - 0.44 10.5 3.8 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function Cation_ATPase_C PF00689.16 EDO04351.1 - 2.3 7.6 6.0 3.3 7.2 4.1 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3784 PF12650.2 EDO04351.1 - 2.5 8.1 5.1 0.51 10.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Ribosomal_L29 PF00831.18 EDO04352.1 - 8.3e-17 60.6 0.3 8.3e-17 60.6 0.2 2.2 2 0 0 2 2 2 2 Ribosomal L29 protein zf-C2H2 PF00096.21 EDO04354.1 - 1.6e-19 68.9 63.2 4.5e-06 26.6 0.4 10.7 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO04354.1 - 6.6e-15 54.5 30.1 5e-07 29.6 1.6 7.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO04354.1 - 1.2e-07 31.5 72.4 0.0022 18.1 0.1 10.3 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO04354.1 - 0.015 15.1 0.2 0.015 15.1 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO04354.1 - 0.055 13.6 0.1 0.055 13.6 0.0 7.4 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding Pertussis_S2S3 PF02918.10 EDO04354.1 - 0.093 12.4 0.9 0.2 11.3 0.6 1.5 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain zf-BED PF02892.10 EDO04354.1 - 0.34 10.6 19.6 0.52 10.1 1.0 4.3 2 1 2 4 4 4 0 BED zinc finger zf-met PF12874.2 EDO04354.1 - 2.8 8.2 31.1 4.2 7.7 0.5 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DEAD PF00270.24 EDO04356.1 - 3.8e-44 150.1 0.0 3.1e-43 147.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO04356.1 - 9.3e-24 83.1 0.0 2.8e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO04356.1 - 0.002 17.0 0.0 0.0044 15.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDO04356.1 - 0.0059 16.4 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MCPVI PF02993.9 EDO04357.1 - 6.1 6.9 12.7 13 5.8 8.8 1.6 1 0 0 1 1 1 0 Minor capsid protein VI Dicty_REP PF05086.7 EDO04357.1 - 7.4 4.1 6.7 8.5 3.9 4.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aa_trans PF01490.13 EDO04358.1 - 2.9e-25 88.6 32.1 4.4e-25 88.0 22.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Exo_endo_phos_2 PF14529.1 EDO04363.1 - 4e-21 74.8 0.2 1.1e-20 73.4 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDO04363.1 - 0.00058 19.8 0.1 0.00098 19.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDO04363.1 - 0.032 13.8 0.3 0.084 12.5 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle WSC PF01822.14 EDO04366.1 - 1.6e-40 136.8 34.5 6.8e-17 61.1 5.6 3.5 3 0 0 3 3 3 3 WSC domain SNF2_N PF00176.18 EDO04366.1 - 4.9e-24 84.6 0.0 7.9e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO04366.1 - 3.7e-09 36.3 0.0 4.3e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EDO04366.1 - 0.0023 17.7 2.4 0.0061 16.3 1.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO04366.1 - 0.0034 17.0 3.8 0.0072 15.9 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PQQ_3 PF13570.1 EDO04366.1 - 0.0035 17.5 5.3 0.049 13.9 0.0 3.9 3 0 0 3 3 3 1 PQQ-like domain zf-RING_5 PF14634.1 EDO04366.1 - 0.078 12.7 4.8 0.18 11.5 3.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Flavokinase PF01687.12 EDO04366.1 - 0.087 12.7 0.1 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 Riboflavin kinase zf-C3HC4_2 PF13923.1 EDO04366.1 - 0.13 12.3 3.9 0.63 10.1 2.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PBP1_TM PF14812.1 EDO04366.1 - 0.18 12.1 0.8 0.61 10.4 0.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Nse PF11789.3 EDO04366.1 - 0.25 10.8 2.2 0.48 9.9 1.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2HC_2 PF13913.1 EDO04366.1 - 1.5 8.5 5.1 0.17 11.5 0.2 2.0 2 0 0 2 2 1 0 zinc-finger of a C2HC-type Nup84_Nup100 PF04121.8 EDO04368.1 - 5.4e-72 242.5 0.0 2.3e-71 240.4 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 PVL_ORF50 PF07768.6 EDO04370.1 - 3.4 7.6 11.6 5.7 6.9 8.1 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family BTV_NS2 PF04514.7 EDO04370.1 - 5.8 5.7 10.7 2.2 7.0 4.0 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Ligase_CoA PF00549.14 EDO04371.1 - 7.6e-34 116.5 4.2 1.1e-17 64.0 0.5 2.2 2 0 0 2 2 2 2 CoA-ligase Succ_CoA_lig PF13607.1 EDO04371.1 - 5.7e-09 35.6 0.0 8e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.14 EDO04371.1 - 0.023 15.1 0.2 0.22 12.0 0.0 2.7 3 0 0 3 3 3 0 CoA binding domain HET PF06985.6 EDO04372.1 - 0.038 14.1 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF4347 PF14252.1 EDO04376.1 - 0.025 14.0 0.1 0.045 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) Attachment_P66 PF11263.3 EDO04376.1 - 0.042 12.8 0.1 0.048 12.6 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 ApoC-I PF04691.7 EDO04376.1 - 0.048 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF3445 PF11927.3 EDO04379.1 - 2.1e-08 33.8 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FAP PF07174.6 EDO04379.1 - 0.13 11.5 11.6 0.16 11.2 8.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SOG2 PF10428.4 EDO04379.1 - 3 6.3 11.1 3.2 6.3 7.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 EDO04379.1 - 7.3 5.8 18.0 8.5 5.6 12.5 1.1 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EDO04381.1 - 1.2e-19 70.8 0.5 3.1e-12 46.7 0.1 2.5 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDO04381.1 - 2.8e-07 30.5 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO04381.1 - 3.6e-05 23.5 1.1 0.016 14.8 0.0 2.6 2 1 1 3 3 3 2 KR domain NAD_binding_10 PF13460.1 EDO04381.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF2493 PF10686.4 EDO04381.1 - 0.05 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Aldedh PF00171.17 EDO04382.1 - 9e-155 515.4 0.1 1e-154 515.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDO04382.1 - 0.053 12.7 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3645 PF12359.3 EDO04385.1 - 0.03 13.4 1.4 0.15 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3645) RVT_1 PF00078.22 EDO04386.1 - 1.4e-06 27.8 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ACR_tran PF00873.14 EDO04386.1 - 0.47 7.7 4.3 0.69 7.2 3.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Lzipper-MIP1 PF14389.1 EDO04386.1 - 0.68 10.0 6.4 0.94 9.6 2.6 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 HgmA PF04209.8 EDO04390.1 - 4.5e-151 503.0 0.1 5.4e-151 502.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.17 EDO04391.1 - 3e-63 213.9 0.0 3.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EDO04393.1 - 1.4e-08 34.4 13.9 2.6e-08 33.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3138 PF11336.3 EDO04393.1 - 0.037 12.1 0.0 0.058 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LPP PF04728.8 EDO04393.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fungal_trans PF04082.13 EDO04395.1 - 2e-06 26.8 0.8 1.2e-05 24.3 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 EDO04396.1 - 9.6e-50 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EDO04396.1 - 4.2e-21 74.9 0.0 6.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Dna2 PF08696.6 EDO04399.1 - 3.6e-72 242.0 0.0 9.1e-72 240.7 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EDO04399.1 - 3.6e-52 176.6 0.0 6.2e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO04399.1 - 3.1e-39 134.9 0.1 2.6e-36 125.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO04399.1 - 4.6e-13 49.1 0.0 1.4e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO04399.1 - 4.5e-12 45.5 0.1 4.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 EDO04399.1 - 1.1e-08 35.2 0.1 5.5e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EDO04399.1 - 4.8e-07 29.4 0.0 8.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EDO04399.1 - 4.9e-07 29.5 0.7 0.28 10.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EDO04399.1 - 0.00049 19.4 1.2 0.0008 18.7 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EDO04399.1 - 0.00059 19.5 0.0 0.0017 18.0 0.0 1.8 1 1 0 1 1 1 1 Helicase DUF911 PF06023.7 EDO04399.1 - 0.00066 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) SRP54 PF00448.17 EDO04399.1 - 0.0009 18.7 0.1 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EDO04399.1 - 0.0013 18.4 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EDO04399.1 - 0.0017 17.3 0.0 0.004 16.1 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EDO04399.1 - 0.0027 17.7 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 EDO04399.1 - 0.0063 15.9 0.3 0.02 14.3 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 EDO04399.1 - 0.015 14.3 0.0 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EDO04399.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDO04399.1 - 0.033 13.1 0.1 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 EDO04399.1 - 0.035 13.9 0.2 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EDO04399.1 - 0.063 13.4 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EDO04399.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EDO04399.1 - 0.097 12.8 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EDO04399.1 - 0.097 12.3 0.2 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 NTPase DUF1413 PF07205.6 EDO04399.1 - 0.14 11.7 0.9 0.36 10.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Mito_carr PF00153.22 EDO04400.1 - 7.6e-65 214.6 1.1 4.7e-21 74.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EDO04401.1 - 5e-16 58.6 0.0 1.5e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04401.1 - 1.9e-07 30.4 0.0 1.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 EDO04402.1 - 7.2e-31 107.4 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ESSS PF10183.4 EDO04403.1 - 4.5e-28 97.7 0.1 5.3e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Daxx PF03344.10 EDO04407.1 - 2.7 6.3 12.1 3.4 6.0 8.4 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EDO04407.1 - 4 5.2 10.3 4.2 5.1 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family RuBisCO_large PF00016.15 EDO04409.1 - 0.021 13.6 0.0 0.024 13.4 0.0 1.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain ETF_QO PF05187.8 EDO04410.1 - 5e-45 152.0 0.0 9.9e-45 151.0 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 EDO04410.1 - 7e-07 29.1 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO04410.1 - 1.6e-06 27.2 1.6 0.00014 20.9 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO04410.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO04410.1 - 0.00016 20.6 0.7 0.0022 16.8 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EDO04410.1 - 0.00016 20.8 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO04410.1 - 0.00026 19.5 0.5 0.0004 18.9 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EDO04410.1 - 0.00043 19.4 0.0 0.0021 17.1 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 EDO04410.1 - 0.00052 18.7 0.0 0.16 10.5 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EDO04410.1 - 0.00089 18.4 0.1 0.0017 17.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EDO04410.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO04410.1 - 0.0022 17.8 0.3 0.0058 16.4 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO04410.1 - 0.0022 18.3 0.1 4.8 7.6 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EDO04410.1 - 0.012 15.9 0.9 0.042 14.2 0.6 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 EDO04410.1 - 0.023 13.6 0.2 0.032 13.1 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EDO04410.1 - 0.078 11.8 0.1 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Internalin_N PF12354.3 EDO04410.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Mem_trans PF03547.13 EDO04413.1 - 2 6.6 4.2 2.2 6.5 2.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Mucin PF01456.12 EDO04413.1 - 2.1 8.1 14.1 3.4 7.4 9.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EDO04413.1 - 7.8 4.1 8.6 9.2 3.8 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.1 EDO04414.1 - 2.3e-14 52.9 3.5 1.1e-13 50.8 2.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO04414.1 - 1.8e-13 50.3 5.1 5.1e-12 45.7 2.6 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO04414.1 - 1.1e-08 34.5 4.5 6e-08 32.2 3.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO04414.1 - 4.6e-08 32.9 4.9 7.4e-08 32.3 2.4 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO04414.1 - 8.2e-08 31.9 2.7 2.3e-07 30.5 1.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EDO04414.1 - 3e-07 30.0 2.4 6e-07 29.0 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO04414.1 - 9.3e-07 28.4 0.2 8.2e-05 22.2 0.1 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.1 EDO04414.1 - 1.4e-06 27.9 4.3 1.4e-06 27.9 3.0 1.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.3 EDO04414.1 - 5.7e-05 22.5 2.4 0.018 14.5 0.4 2.3 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EDO04414.1 - 0.0034 16.9 2.8 0.016 14.7 1.9 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EDO04414.1 - 0.013 15.4 5.5 0.037 13.9 2.7 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EDO04414.1 - 0.053 13.4 1.5 0.053 13.4 1.0 2.6 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Pellino PF04710.9 EDO04414.1 - 0.088 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Pellino Prok-RING_4 PF14447.1 EDO04414.1 - 0.62 9.6 3.1 0.79 9.3 0.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UPF0547 PF10571.4 EDO04414.1 - 0.68 9.6 10.6 1.4 8.6 0.2 3.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 FYVE PF01363.16 EDO04414.1 - 1.1 9.1 4.1 2.7 7.9 2.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.1 EDO04416.1 - 0.0046 16.5 0.1 0.0085 15.7 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-rbx1 PF12678.2 EDO04418.1 - 2.4e-09 37.1 1.7 3.8e-09 36.5 1.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDO04418.1 - 5.8e-09 35.6 4.8 1e-08 34.8 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EDO04418.1 - 2.9e-07 30.2 0.6 4.5e-07 29.6 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO04418.1 - 1.7e-05 24.3 4.7 2.9e-05 23.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO04418.1 - 3e-05 23.9 1.8 5.3e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDO04418.1 - 0.00012 21.5 1.1 0.0002 20.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EDO04418.1 - 0.034 13.8 4.1 0.055 13.2 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDO04418.1 - 0.049 13.3 1.3 0.049 13.3 0.9 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EDO04418.1 - 0.086 12.5 3.4 0.13 11.9 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDO04418.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DDE_1 PF03184.14 EDO04419.1 - 9.8e-36 122.9 0.6 9.8e-36 122.9 0.4 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04419.1 - 1.1e-13 50.7 0.0 3.6e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3450 PF11932.3 EDO04419.1 - 1.7 7.8 7.8 0.076 12.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-RING_2 PF13639.1 EDO04420.1 - 3.4e-09 36.3 3.9 6.5e-09 35.4 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain IncA PF04156.9 EDO04420.1 - 7.3e-09 35.4 8.2 6.8e-05 22.5 2.0 2.4 1 1 0 2 2 2 2 IncA protein zf-rbx1 PF12678.2 EDO04420.1 - 1.2e-07 31.6 1.6 2.2e-07 30.8 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO04420.1 - 2.6e-06 27.3 1.0 5.2e-06 26.3 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_13 PF13166.1 EDO04420.1 - 3.1e-06 25.9 3.2 5.3e-06 25.2 2.2 1.3 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 EDO04420.1 - 4.6e-06 26.0 1.2 0.00029 20.1 0.1 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 EDO04420.1 - 6.6e-06 26.3 11.8 0.00049 20.3 1.5 3.2 1 1 2 3 3 2 2 Snapin/Pallidin FlaC_arch PF05377.6 EDO04420.1 - 1.6e-05 24.6 1.1 0.2 11.5 0.2 4.4 4 1 1 5 5 5 1 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 EDO04420.1 - 7.7e-05 22.4 6.1 0.047 13.4 0.3 3.1 1 1 1 2 2 2 2 Prefoldin subunit AKNA PF12443.3 EDO04420.1 - 8.2e-05 22.5 9.3 0.35 10.9 0.1 3.5 2 1 1 3 3 3 1 AT-hook-containing transcription factor Med9 PF07544.8 EDO04420.1 - 0.00011 21.8 5.5 0.0024 17.5 0.5 2.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 zf-C3HC4 PF00097.20 EDO04420.1 - 0.00012 21.6 3.7 0.0002 20.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EzrA PF06160.7 EDO04420.1 - 0.00013 20.2 5.5 0.00058 18.1 3.7 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA ADIP PF11559.3 EDO04420.1 - 0.00015 21.7 10.5 0.081 12.8 1.9 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EDO04420.1 - 0.00015 21.1 5.5 0.063 12.7 0.2 3.3 3 0 0 3 3 3 1 Septum formation initiator zf-Apc11 PF12861.2 EDO04420.1 - 0.00024 20.8 0.2 0.00047 19.9 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Spc7 PF08317.6 EDO04420.1 - 0.00029 19.6 5.6 0.013 14.1 0.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EDO04420.1 - 0.0003 20.7 3.5 0.088 12.8 0.4 2.4 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain MscS_porin PF12795.2 EDO04420.1 - 0.00036 19.9 7.1 0.00036 19.9 4.9 3.2 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain FliJ PF02050.11 EDO04420.1 - 0.00041 20.4 8.5 0.0018 18.2 2.4 2.5 2 0 0 2 2 2 1 Flagellar FliJ protein Tropomyosin_1 PF12718.2 EDO04420.1 - 0.00089 19.1 0.5 0.013 15.3 0.0 2.2 1 1 0 2 2 2 1 Tropomyosin like zf-RING_UBOX PF13445.1 EDO04420.1 - 0.00099 18.7 0.4 0.0032 17.1 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF2968 PF11180.3 EDO04420.1 - 0.0013 18.1 3.9 0.0013 18.1 2.7 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.4 EDO04420.1 - 0.0015 17.0 1.3 0.0015 17.0 0.9 2.0 1 1 1 2 2 2 1 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.4 EDO04420.1 - 0.0015 18.3 5.6 0.23 11.2 3.9 2.5 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EDO04420.1 - 0.0017 18.2 11.5 0.0023 17.7 0.9 3.0 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EDO04420.1 - 0.0018 17.3 13.3 0.29 10.0 5.0 2.9 1 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EDO04420.1 - 0.0021 17.8 5.9 0.022 14.5 0.4 2.3 1 1 1 2 2 2 1 Laminin Domain II Fib_alpha PF08702.5 EDO04420.1 - 0.0021 18.1 8.5 0.14 12.3 2.4 2.9 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EDO04420.1 - 0.0021 17.9 1.6 0.58 10.1 0.1 3.5 3 0 0 3 3 3 1 bZIP transcription factor Myosin_tail_1 PF01576.14 EDO04420.1 - 0.0023 15.7 1.9 0.0044 14.8 1.3 1.3 1 1 0 1 1 1 1 Myosin tail TBPIP PF07106.8 EDO04420.1 - 0.0025 17.3 7.0 0.37 10.3 0.2 2.5 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 EDO04420.1 - 0.0027 17.2 6.8 0.037 13.4 1.4 2.2 1 1 1 2 2 2 1 Intermediate filament protein GAS PF13851.1 EDO04420.1 - 0.0028 16.8 4.8 0.02 14.1 0.2 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2730 PF10805.3 EDO04420.1 - 0.0028 17.3 4.3 0.035 13.8 0.9 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) bZIP_2 PF07716.10 EDO04420.1 - 0.0029 17.4 13.4 0.81 9.5 1.3 4.2 3 1 1 4 4 3 1 Basic region leucine zipper CALCOCO1 PF07888.6 EDO04420.1 - 0.0029 15.9 1.5 0.004 15.5 1.0 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.7 EDO04420.1 - 0.0031 17.7 8.7 3.2 8.0 4.5 3.7 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Laminin_I PF06008.9 EDO04420.1 - 0.0036 16.6 6.8 0.0062 15.8 1.7 2.3 1 1 1 2 2 2 1 Laminin Domain I PspA_IM30 PF04012.7 EDO04420.1 - 0.0037 16.6 7.0 0.22 10.8 0.5 2.3 1 1 0 2 2 2 2 PspA/IM30 family AAA_27 PF13514.1 EDO04420.1 - 0.0039 14.9 9.2 0.17 9.5 1.9 2.3 1 1 1 2 2 2 2 AAA domain LPP PF04728.8 EDO04420.1 - 0.0041 16.8 1.1 0.78 9.5 0.0 3.4 3 1 0 3 3 2 1 Lipoprotein leucine-zipper BLOC1_2 PF10046.4 EDO04420.1 - 0.0051 16.9 2.3 0.57 10.3 0.0 3.0 1 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3540 PF12059.3 EDO04420.1 - 0.0058 16.2 2.8 0.8 9.3 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3540) zf-RING_5 PF14634.1 EDO04420.1 - 0.006 16.2 3.1 0.0096 15.6 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO04420.1 - 0.0064 16.1 2.5 0.01 15.4 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Herpes_U30 PF04523.8 EDO04420.1 - 0.0064 14.0 5.0 0.01 13.3 3.4 1.3 1 0 0 1 1 1 1 Herpes virus tegument protein U30 DUF3584 PF12128.3 EDO04420.1 - 0.0072 13.7 2.8 0.01 13.2 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FliD_C PF07195.7 EDO04420.1 - 0.0078 15.5 5.0 0.49 9.6 0.3 2.9 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.7 EDO04420.1 - 0.0086 15.8 3.4 2.3 8.0 0.1 2.6 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 EDO04420.1 - 0.011 16.1 20.3 0.12 12.7 2.7 3.9 3 1 0 4 4 3 0 SlyX Tropomyosin PF00261.15 EDO04420.1 - 0.011 14.7 2.4 0.33 10.0 0.2 2.1 1 1 1 2 2 2 0 Tropomyosin DUF869 PF05911.6 EDO04420.1 - 0.012 13.8 1.5 0.058 11.6 0.2 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Ax_dynein_light PF10211.4 EDO04420.1 - 0.014 15.2 3.7 1.4 8.7 0.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Mnd1 PF03962.10 EDO04420.1 - 0.015 15.0 5.0 1.5 8.4 0.2 2.5 1 1 1 2 2 2 0 Mnd1 family DUF1664 PF07889.7 EDO04420.1 - 0.019 14.7 4.7 0.21 11.4 0.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4_4 PF15227.1 EDO04420.1 - 0.021 14.6 0.2 0.043 13.6 0.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DASH_Spc34 PF08657.5 EDO04420.1 - 0.023 14.3 1.1 0.023 14.3 0.7 2.7 1 1 2 3 3 3 0 DASH complex subunit Spc34 Uds1 PF15456.1 EDO04420.1 - 0.023 14.6 3.6 0.11 12.4 0.6 2.5 1 1 1 2 2 2 0 Up-regulated During Septation zf-Nse PF11789.3 EDO04420.1 - 0.024 14.1 0.5 0.057 12.9 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prefoldin PF02996.12 EDO04420.1 - 0.025 14.2 7.5 1.6 8.3 0.3 3.5 2 1 1 3 3 3 0 Prefoldin subunit DUF812 PF05667.6 EDO04420.1 - 0.035 12.6 5.4 0.12 10.8 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 EDO04420.1 - 0.042 12.8 4.5 0.064 12.2 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 WEMBL PF05701.6 EDO04420.1 - 0.05 12.0 0.6 0.07 11.5 0.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Mitofilin PF09731.4 EDO04420.1 - 0.05 12.2 9.6 0.025 13.2 0.6 2.4 1 1 2 3 3 3 0 Mitochondrial inner membrane protein COG5 PF10392.4 EDO04420.1 - 0.051 13.5 11.5 0.56 10.1 2.1 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Sipho_Gp157 PF05565.6 EDO04420.1 - 0.051 13.1 0.4 0.8 9.2 0.1 2.5 1 1 1 2 2 2 0 Siphovirus Gp157 TACC PF05010.9 EDO04420.1 - 0.053 13.2 0.3 0.092 12.4 0.2 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) V_ATPase_I PF01496.14 EDO04420.1 - 0.053 11.3 2.7 0.075 10.8 1.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EDO04420.1 - 0.054 13.3 12.5 0.28 10.9 1.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cast PF10174.4 EDO04420.1 - 0.058 11.4 8.9 0.39 8.7 6.2 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HalX PF08663.5 EDO04420.1 - 0.061 13.3 2.8 16 5.5 0.0 3.7 3 1 1 4 4 2 0 HalX domain PTRF_SDPR PF15237.1 EDO04420.1 - 0.067 12.5 3.6 0.046 13.1 1.2 1.5 1 1 0 1 1 1 0 PTRF/SDPR family DivIVA PF05103.8 EDO04420.1 - 0.077 13.0 6.1 0.63 10.0 0.3 3.2 2 1 1 3 3 3 0 DivIVA protein DUF342 PF03961.8 EDO04420.1 - 0.092 11.1 5.8 1.2 7.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF16 PF01519.11 EDO04420.1 - 0.1 12.7 2.7 7.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Bacillus_HBL PF05791.6 EDO04420.1 - 0.11 11.8 6.0 0.37 10.1 1.0 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4140 PF13600.1 EDO04420.1 - 0.11 12.9 9.1 1.7 9.1 0.5 3.7 2 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EDO04420.1 - 0.12 12.7 7.5 6.4 7.1 2.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IFT57 PF10498.4 EDO04420.1 - 0.12 11.0 4.8 0.93 8.1 3.4 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Lipoprotein_6 PF01441.14 EDO04420.1 - 0.13 12.1 0.1 0.26 11.1 0.0 1.6 2 0 0 2 2 1 0 Lipoprotein YlbD_coat PF14071.1 EDO04420.1 - 0.14 12.2 7.0 17 5.4 0.2 3.5 1 1 2 3 3 3 0 Putative coat protein DUF1192 PF06698.6 EDO04420.1 - 0.14 12.0 7.2 0.68 9.7 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF948 PF06103.6 EDO04420.1 - 0.14 12.0 3.1 2.7 7.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.1 EDO04420.1 - 0.14 12.4 7.7 0.097 12.9 0.6 3.4 3 1 1 4 4 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3847 PF12958.2 EDO04420.1 - 0.16 11.7 9.4 1.5 8.6 1.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) DUF4407 PF14362.1 EDO04420.1 - 0.19 10.6 1.1 2.4 7.0 0.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 EDO04420.1 - 0.26 11.1 5.7 1.3 8.8 0.2 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EDO04420.1 - 0.27 10.9 9.6 2.9 7.6 0.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.1 EDO04420.1 - 0.27 10.5 8.4 0.8 8.9 0.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) EMP24_GP25L PF01105.19 EDO04420.1 - 0.29 10.8 5.8 5.1 6.7 1.4 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD vATP-synt_E PF01991.13 EDO04420.1 - 0.29 10.3 6.2 0.079 12.2 0.4 2.5 2 1 1 3 3 2 0 ATP synthase (E/31 kDa) subunit COG2 PF06148.6 EDO04420.1 - 0.3 10.9 5.4 0.7 9.7 1.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.3 EDO04420.1 - 0.36 10.0 10.9 0.59 9.3 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 EDO04420.1 - 0.38 10.6 10.9 1 9.3 1.9 3.4 2 1 0 3 3 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.6 EDO04420.1 - 0.42 10.3 7.5 3.6 7.3 0.6 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 YPEB PF14620.1 EDO04420.1 - 0.43 9.5 3.6 2 7.3 0.1 2.2 1 1 2 3 3 3 0 YpeB sporulation MbeD_MobD PF04899.7 EDO04420.1 - 0.48 10.3 6.1 0.98 9.3 1.2 3.2 1 1 2 3 3 3 0 MbeD/MobD like SseC PF04888.7 EDO04420.1 - 0.49 9.6 2.5 0.91 8.7 0.1 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DASH_Hsk3 PF08227.6 EDO04420.1 - 0.52 10.5 10.0 12 6.1 0.0 4.6 4 2 0 4 4 3 0 DASH complex subunit Hsk3 like HrpB7 PF09486.5 EDO04420.1 - 0.58 10.0 5.1 6.3 6.7 3.7 2.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) UPF0547 PF10571.4 EDO04420.1 - 0.63 9.7 2.9 13 5.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Occludin_ELL PF07303.8 EDO04420.1 - 0.63 10.7 4.8 17 6.1 0.4 3.4 2 1 2 4 4 3 0 Occludin homology domain YscO PF07321.7 EDO04420.1 - 0.76 9.5 8.7 1.1 9.1 2.3 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO HSBP1 PF06825.7 EDO04420.1 - 0.83 9.2 7.6 8 6.1 1.1 4.4 3 1 0 4 4 2 0 Heat shock factor binding protein 1 FUSC PF04632.7 EDO04420.1 - 1.2 7.5 7.8 0.97 7.7 4.3 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Matrilin_ccoil PF10393.4 EDO04420.1 - 1.2 8.5 9.9 0.24 10.7 0.5 3.4 4 0 0 4 4 2 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-Q PF13094.1 EDO04420.1 - 1.3 9.0 8.2 0.49 10.3 0.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3373 PF11853.3 EDO04420.1 - 1.4 7.3 3.1 4.8 5.5 0.4 2.1 1 1 2 3 3 2 0 Protein of unknown function (DUF3373) STAT_alpha PF01017.15 EDO04420.1 - 1.5 8.5 12.9 1.7 8.3 1.4 3.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Phasin PF05597.6 EDO04420.1 - 1.5 8.6 4.1 20 4.9 0.2 3.5 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cluap1 PF10234.4 EDO04420.1 - 1.5 7.9 6.7 1.1 8.4 0.6 2.1 1 1 0 2 2 2 0 Clusterin-associated protein-1 DUF2681 PF10883.3 EDO04420.1 - 1.5 9.0 7.2 3.3 7.9 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Syntaxin PF00804.20 EDO04420.1 - 1.7 8.8 14.3 3.1 7.9 1.7 3.0 2 1 1 3 3 2 0 Syntaxin Viral_P18 PF04521.8 EDO04420.1 - 1.8 8.0 8.4 13 5.2 0.3 3.2 1 1 2 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Prominin PF05478.6 EDO04420.1 - 2.1 5.7 5.2 6.2 4.2 3.6 1.6 1 1 0 1 1 1 0 Prominin Spectrin PF00435.16 EDO04420.1 - 2.1 8.6 11.3 3 8.1 0.7 3.1 2 1 1 3 3 2 0 Spectrin repeat Cep57_MT_bd PF06657.8 EDO04420.1 - 2.2 8.2 10.0 17 5.4 2.6 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tmpp129 PF10272.4 EDO04420.1 - 2.7 6.6 6.7 7.6 5.1 0.1 2.7 2 1 1 3 3 3 0 Putative transmembrane protein precursor DUF904 PF06005.7 EDO04420.1 - 2.8 8.3 12.9 5.2e+03 -2.2 8.9 3.0 1 1 0 1 1 0 0 Protein of unknown function (DUF904) DegS PF05384.6 EDO04420.1 - 3.7 6.7 10.2 2.7 7.1 0.4 2.8 3 0 0 3 3 3 0 Sensor protein DegS TPR_MLP1_2 PF07926.7 EDO04420.1 - 3.9 7.2 8.5 5.1e+02 0.3 5.9 3.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.13 EDO04420.1 - 4.2 6.8 9.8 32 3.9 6.8 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Nup54 PF13874.1 EDO04420.1 - 5.1 6.7 19.7 1 8.9 4.2 2.8 2 1 0 3 3 2 0 Nucleoporin complex subunit 54 V-SNARE PF05008.10 EDO04420.1 - 5.2 7.3 10.3 4.6 7.4 0.7 3.6 3 1 0 4 4 2 0 Vesicle transport v-SNARE protein N-terminus MCC-bdg_PDZ PF10506.4 EDO04420.1 - 5.4 6.9 10.0 0.51 10.2 0.7 3.4 3 1 0 4 4 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sec2p PF06428.6 EDO04420.1 - 5.5 6.8 7.6 9.3 6.1 0.4 2.9 2 1 1 3 3 2 0 GDP/GTP exchange factor Sec2p UPF0184 PF03670.8 EDO04420.1 - 5.5 7.2 5.7 5.2 7.3 0.5 3.0 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0184) Rootletin PF15035.1 EDO04420.1 - 8.7 6.2 14.7 41 4.0 7.0 3.0 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Pyr_redox_3 PF13738.1 EDO04421.1 - 7e-23 81.7 0.0 1.8e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDO04421.1 - 2.1e-10 39.4 0.2 4e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDO04421.1 - 3.2e-07 30.2 0.1 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO04421.1 - 9.5e-06 24.7 0.0 0.00027 19.9 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EDO04421.1 - 0.19 11.8 0.0 8.4 6.5 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Cupin_8 PF13621.1 EDO04422.1 - 1.9e-27 96.3 0.0 2.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDO04422.1 - 0.0016 18.6 0.1 0.037 14.2 0.0 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EDO04422.1 - 0.013 14.7 0.0 0.06 12.5 0.0 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.6 EDO04422.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Zn_clus PF00172.13 EDO04424.1 - 3.4e-07 30.0 9.7 6.4e-07 29.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDO04424.1 - 0.00046 18.8 0.1 0.0022 16.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CK_II_beta PF01214.13 EDO04425.1 - 3.5e-77 258.0 0.0 6.5e-77 257.1 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EDO04425.1 - 0.0012 19.3 8.6 0.0012 19.3 6.0 1.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.6 EDO04425.1 - 0.028 12.5 2.4 0.036 12.1 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TIMELESS PF04821.9 EDO04425.1 - 0.12 11.6 0.3 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Timeless protein Nucleoplasmin PF03066.10 EDO04425.1 - 0.19 11.2 6.8 0.31 10.5 4.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 EDO04425.1 - 0.37 8.6 1.7 0.51 8.1 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EDO04425.1 - 0.71 7.7 5.5 0.68 7.7 2.9 1.6 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 EDO04425.1 - 0.75 7.7 4.5 0.98 7.3 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EDO04425.1 - 7.8 6.8 11.6 6 7.2 4.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VIT1 PF01988.14 EDO04427.1 - 1.7e-59 200.8 3.7 2.1e-59 200.5 2.6 1.1 1 0 0 1 1 1 1 VIT family DUF2391 PF09622.5 EDO04427.1 - 0.041 13.0 0.2 0.065 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Prefoldin PF02996.12 EDO04428.1 - 8e-24 83.6 0.1 1.1e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EDO04428.1 - 0.0016 18.1 2.5 0.83 9.4 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EDO04428.1 - 0.0058 16.5 1.4 0.013 15.4 0.9 1.7 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Sec2p PF06428.6 EDO04428.1 - 0.008 16.0 3.5 0.27 11.1 0.3 2.4 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p CENP-Q PF13094.1 EDO04428.1 - 0.019 14.9 1.6 0.2 11.6 0.6 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit tRNA_U5-meth_tr PF05958.6 EDO04430.1 - 0.095 11.3 0.1 0.095 11.3 0.0 1.0 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase AAA PF00004.24 EDO04431.1 - 3.5e-15 56.3 0.0 9.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO04431.1 - 2.5e-11 43.8 0.0 4.9e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO04431.1 - 2.1e-08 34.4 0.0 1.8e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 EDO04431.1 - 8.1e-07 28.8 0.1 2.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 BAH domain AAA_17 PF13207.1 EDO04431.1 - 1.3e-05 26.0 0.3 0.0028 18.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EDO04431.1 - 0.00033 20.3 0.4 0.0013 18.4 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 EDO04431.1 - 0.0041 16.1 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase NACHT PF05729.7 EDO04431.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EDO04431.1 - 0.0074 16.0 0.4 0.43 10.2 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EDO04431.1 - 0.015 15.5 0.9 0.076 13.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EDO04431.1 - 0.015 14.8 0.8 0.034 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO04431.1 - 0.022 14.7 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EDO04431.1 - 0.34 10.1 3.3 0.71 9.1 0.2 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Vfa1 PF08432.5 EDO04431.1 - 1.7 8.6 8.0 0.62 10.0 1.4 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.27 EDO04432.1 - 1e-52 174.2 12.9 2.8e-09 36.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDO04432.1 - 0.0025 16.0 4.4 2.2 6.3 0.1 4.7 1 1 3 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDO04432.1 - 0.0069 15.8 0.3 1.2 8.5 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EDO04432.1 - 0.067 11.9 0.0 5.6 5.6 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Ank_2 PF12796.2 EDO04433.1 - 1.7e-40 137.2 0.8 2.2e-17 63.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO04433.1 - 6.2e-39 131.1 2.7 4.4e-10 39.4 0.0 5.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO04433.1 - 8.7e-35 118.4 7.3 1.6e-08 34.8 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EDO04433.1 - 8.1e-34 113.7 1.3 7.4e-06 25.5 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EDO04433.1 - 1.1e-29 99.5 0.5 0.002 18.1 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat C1_2 PF03107.11 EDO04436.1 - 0.32 11.1 2.5 1 9.5 0.2 2.4 2 1 0 2 2 2 0 C1 domain ComC PF03047.9 EDO04437.1 - 0.0084 15.5 0.2 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 COMC family CMD PF02627.15 EDO04438.1 - 0.015 15.1 0.2 0.029 14.2 0.1 1.6 1 1 0 1 1 1 0 Carboxymuconolactone decarboxylase family Carn_acyltransf PF00755.15 EDO04440.1 - 1.6e-89 300.5 0.0 2.4e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 EDO04440.1 - 1.1e-77 260.9 0.0 1.9e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDO04440.1 - 5.4e-60 203.3 0.4 1.2e-59 202.2 0.3 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EDO04440.1 - 1.5e-47 162.1 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EDO04440.1 - 1.7e-46 158.1 0.1 4.6e-46 156.7 0.0 1.8 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 EDO04440.1 - 2e-37 128.6 0.2 1.2e-36 126.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EDO04440.1 - 8e-35 119.2 0.0 2.2e-34 117.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EDO04440.1 - 2.7e-18 65.7 1.1 1.6e-17 63.3 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EDO04440.1 - 4.5e-15 55.9 0.0 1.2e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EDO04440.1 - 2.4e-09 38.1 0.0 1.4e-08 35.6 0.0 2.4 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EDO04440.1 - 5.4e-07 30.1 0.0 1.7e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO04440.1 - 9.2e-07 28.7 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO04440.1 - 2.3e-06 27.9 0.0 1.3e-05 25.6 0.0 2.4 3 0 0 3 3 1 1 Methyltransferase domain ADH_N PF08240.7 EDO04440.1 - 2.5e-06 27.2 0.0 5.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EDO04440.1 - 5.8e-06 25.5 0.0 1.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDO04440.1 - 6.3e-06 25.8 0.0 2.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EDO04440.1 - 4e-05 23.7 0.2 0.00017 21.7 0.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PCMT PF01135.14 EDO04440.1 - 0.00031 20.3 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.18 EDO04440.1 - 0.00075 18.5 0.3 0.0015 17.5 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EDO04440.1 - 0.00093 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Polysacc_synt_2 PF02719.10 EDO04440.1 - 0.0088 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EDO04440.1 - 0.051 12.2 0.0 0.09 11.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EDO04440.1 - 0.075 13.4 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Copper-fist PF00649.13 EDO04441.1 - 4.3e-14 51.4 1.9 1.2e-13 49.9 1.3 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain Metallothio_PEC PF02068.11 EDO04441.1 - 0.014 15.7 20.9 0.014 15.7 14.5 4.6 4 1 0 4 4 4 0 Plant PEC family metallothionein EPL1 PF10513.4 EDO04441.1 - 0.047 13.9 2.0 0.094 12.9 1.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Methyltransf_16 PF10294.4 EDO04442.1 - 3.9e-15 55.7 0.0 6.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDO04442.1 - 2.7e-05 24.7 0.0 4.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO04442.1 - 0.0025 17.5 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EDO04442.1 - 0.0025 16.9 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.12 EDO04442.1 - 0.0086 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.7 EDO04442.1 - 0.023 15.2 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDO04442.1 - 0.052 14.0 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EDO04442.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain EGL-1 PF11430.3 EDO04445.1 - 0.25 11.0 1.4 1.6 8.3 0.2 2.1 2 0 0 2 2 2 0 Programmed cell death activator EGL-1 Pkinase PF00069.20 EDO04446.1 - 6.4e-15 54.9 1.0 7e-15 54.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04446.1 - 0.00053 19.1 0.0 0.0058 15.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Oxysterol_BP PF01237.13 EDO04446.1 - 0.016 13.6 2.0 0.021 13.3 1.4 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Rif1_N PF12231.3 EDO04446.1 - 0.055 12.4 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal HTH_psq PF05225.11 EDO04447.1 - 4.6e-12 45.2 0.0 7.6e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO04447.1 - 1.6e-09 37.4 0.0 2.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO04447.1 - 1.7e-05 24.0 0.1 0.00036 19.7 0.0 2.4 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_3 PF01381.17 EDO04447.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix DUF2089 PF09862.4 EDO04447.1 - 0.0087 15.8 0.1 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_23 PF13384.1 EDO04447.1 - 0.013 15.0 0.6 0.039 13.5 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 EDO04447.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EDO04447.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF3404 PF11884.3 EDO04447.1 - 0.07 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Aminotran_1_2 PF00155.16 EDO04453.1 - 1.1e-82 277.8 0.0 1.4e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDO04453.1 - 1.2e-06 27.5 0.0 2.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDO04453.1 - 1.3e-05 23.7 0.0 2.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3405 PF11885.3 EDO04453.1 - 0.0013 17.0 0.2 0.0019 16.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF2570 PF10828.3 EDO04455.1 - 7.5 6.2 8.0 9.9 5.8 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DivIC PF04977.10 EDO04455.1 - 9.6 5.7 9.4 76 2.8 4.4 2.8 2 1 1 3 3 3 0 Septum formation initiator RRM_6 PF14259.1 EDO04457.1 - 8.4e-13 48.1 0.0 1e-05 25.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO04457.1 - 1.6e-10 40.4 0.0 0.00047 19.7 0.0 3.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO04457.1 - 3e-05 23.7 0.0 0.00088 19.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MoaC PF01967.16 EDO04460.1 - 4.3e-50 168.9 2.4 4e-27 94.5 0.2 2.3 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 EDO04460.1 - 1.8e-35 121.4 0.0 2.9e-34 117.5 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EDO04460.1 - 5.2e-20 72.2 0.0 1.3e-19 70.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EDO04460.1 - 0.00037 20.6 0.0 0.00084 19.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EDO04460.1 - 0.00037 20.5 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain EBP PF05241.7 EDO04462.1 - 1.5e-63 213.3 10.7 1.8e-63 213.0 7.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein zf-DHHC PF01529.15 EDO04462.1 - 0.14 11.5 9.3 0.29 10.5 3.5 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1129 PF06570.6 EDO04462.1 - 0.43 9.8 2.1 0.93 8.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_M24 PF00557.19 EDO04465.1 - 1.1e-59 201.5 0.1 1.7e-59 200.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDO04465.1 - 1.3e-21 76.3 0.0 2.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain dsrm PF00035.20 EDO04466.1 - 0.0082 16.7 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif DSPc PF00782.15 EDO04467.1 - 8e-25 86.9 0.0 1.4e-21 76.4 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO04467.1 - 8.6e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EDO04467.1 - 0.011 15.7 0.8 0.058 13.4 0.6 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate Rhodanese PF00581.15 EDO04467.1 - 0.09 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain PTS_2-RNA PF01885.11 EDO04471.1 - 2.4e-65 219.3 0.0 2.9e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RabGAP-TBC PF00566.13 EDO04473.1 - 1.2e-13 51.0 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KH_1 PF00013.24 EDO04475.1 - 4.3e-38 128.7 12.6 2.3e-14 52.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDO04475.1 - 1e-29 101.6 13.8 2.9e-11 42.7 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDO04475.1 - 2.8e-10 39.5 7.7 0.0072 15.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDO04475.1 - 1.7e-08 33.9 5.2 0.029 13.9 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDO04475.1 - 0.00032 20.4 4.7 0.72 9.6 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EDO04475.1 - 0.0063 15.9 0.7 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 dUTPase Cofilin_ADF PF00241.15 EDO04476.1 - 1.1e-14 54.4 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UAA PF08449.6 EDO04477.1 - 1.4e-72 244.2 4.6 5.1e-72 242.3 3.2 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EDO04477.1 - 2.4e-08 34.0 22.4 2.4e-07 30.8 2.6 3.4 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EDO04477.1 - 4.2e-06 26.0 0.2 0.021 13.9 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EDO04477.1 - 4.4e-06 26.8 16.9 2.3e-05 24.5 2.6 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EDO04477.1 - 0.0084 15.7 6.9 0.0084 15.7 4.8 2.4 2 2 0 2 2 2 1 Triose-phosphate Transporter family Pkinase PF00069.20 EDO04478.1 - 2.3e-59 200.6 0.0 3.5e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04478.1 - 4.8e-22 78.2 0.0 8.5e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO04478.1 - 2.5e-07 29.9 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO04478.1 - 0.0027 16.8 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO04478.1 - 0.0055 16.4 0.1 0.031 13.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDO04478.1 - 0.012 14.9 0.2 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 EDO04481.1 - 2.5e-10 39.9 0.0 8.6e-10 38.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EDO04481.1 - 2e-06 27.2 4.4 0.81 9.9 0.0 5.6 6 0 0 6 6 6 3 Leucine Rich repeat F-box PF00646.28 EDO04481.1 - 6e-06 25.7 0.0 2.1e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EDO04481.1 - 1.6e-05 24.3 3.2 2.9 8.2 0.0 5.8 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.2 EDO04481.1 - 0.00043 19.8 6.3 0.0025 17.3 0.0 4.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) PRANC PF09372.5 EDO04481.1 - 0.0036 17.2 0.3 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 PRANC domain MAP65_ASE1 PF03999.7 EDO04481.1 - 0.11 11.1 0.1 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PPR_2 PF13041.1 EDO04483.1 - 5.5e-23 80.6 0.7 8.7e-06 25.6 0.0 8.0 7 1 1 8 8 8 5 PPR repeat family PPR_3 PF13812.1 EDO04483.1 - 4.2e-14 51.5 1.1 0.0054 16.9 0.0 7.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EDO04483.1 - 8.2e-08 31.7 0.8 2.1 8.4 0.0 7.3 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 EDO04483.1 - 3.6e-05 23.1 0.2 0.29 10.6 0.0 4.9 4 0 0 4 4 4 1 PPR repeat ECSIT PF06239.6 EDO04483.1 - 0.0056 15.5 0.0 6.6 5.5 0.0 3.6 2 1 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway His_Phos_2 PF00328.17 EDO04484.1 - 1.2e-17 64.3 0.0 3.2e-16 59.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EDO04485.1 - 3.1e-19 69.6 0.0 4.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-Mss51 PF13824.1 EDO04486.1 - 6.4e-27 93.1 7.5 1.1e-26 92.4 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 CPSF_A PF03178.10 EDO04487.1 - 5.9e-78 262.1 0.0 2.2e-76 257.0 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EDO04487.1 - 2.6e-69 233.6 0.0 4.7e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EDO04487.1 - 0.025 14.4 0.0 0.29 11.0 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Nup160 PF11715.3 EDO04487.1 - 0.05 11.7 0.3 2.5 6.1 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 UBA_4 PF14555.1 EDO04488.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain zf-RING_5 PF14634.1 EDO04488.1 - 0.034 13.8 3.0 0.034 13.8 2.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain LysM PF01476.15 EDO04488.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 LysM domain zf-RING_2 PF13639.1 EDO04488.1 - 5.4 6.9 10.1 0.26 11.1 2.6 1.9 2 0 0 2 2 2 0 Ring finger domain Ank_2 PF12796.2 EDO04489.1 - 1.4e-27 95.8 0.2 8.9e-18 64.4 0.4 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04489.1 - 6.2e-21 73.0 5.7 4.8e-09 35.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EDO04489.1 - 4.5e-17 61.6 1.7 1.6e-07 31.3 0.3 5.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO04489.1 - 8.8e-17 61.1 1.2 2.1e-08 34.4 0.0 4.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO04489.1 - 4.4e-15 54.2 0.5 4.4e-07 29.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Borrelia_P83 PF05262.6 EDO04489.1 - 7.7e-11 40.9 0.6 7.7e-11 40.9 0.4 2.3 2 1 0 2 2 2 1 Borrelia P83/100 protein 2OG-FeII_Oxy_2 PF13532.1 EDO04490.1 - 2.3e-13 50.3 0.0 1.3e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDO04490.1 - 1.6e-05 25.1 0.0 5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HTH_18 PF12833.2 EDO04491.1 - 0.11 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MMR_HSR1 PF01926.18 EDO04492.1 - 1.5e-18 66.8 0.2 3.7e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 EDO04492.1 - 1.2e-12 47.4 0.2 3.4e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EDO04492.1 - 7.2e-10 38.3 0.0 4.1e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO04492.1 - 0.0001 22.1 0.4 0.02 14.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EDO04492.1 - 0.00017 21.0 0.3 2.1 7.7 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EDO04492.1 - 0.0041 15.9 0.1 0.011 14.4 0.1 1.7 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EDO04492.1 - 0.011 16.2 0.1 0.045 14.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EDO04492.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 AIG1 family DUF211 PF02680.9 EDO04492.1 - 0.11 12.3 1.1 0.37 10.6 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 HTH_Tnp_Tc5 PF03221.11 EDO04494.1 - 7.5e-17 60.9 0.1 1.4e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EDO04494.1 - 2.1e-06 27.0 0.6 3.6e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EDO04494.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 EDO04494.1 - 0.032 14.0 0.1 0.092 12.5 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_38 PF13936.1 EDO04494.1 - 0.047 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EDO04494.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 EDO04494.1 - 0.12 12.0 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.2 EDO04494.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.1 EDO04494.1 - 0.22 11.5 0.3 4.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3671 PF12420.3 EDO04495.1 - 0.94 9.4 6.0 1.1 9.3 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function PXA PF02194.10 EDO04496.1 - 1.5e-35 122.4 0.0 4.4e-35 120.9 0.0 1.7 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EDO04496.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Sorting nexin C terminal Mis12 PF05859.7 EDO04498.1 - 6.5e-37 126.5 0.0 1.1e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Cation_efflux PF01545.16 EDO04500.1 - 0.023 13.7 3.4 0.035 13.1 2.4 1.3 1 0 0 1 1 1 0 Cation efflux family DUF3754 PF12576.3 EDO04500.1 - 0.79 9.3 3.0 4.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) NfeD PF01957.13 EDO04501.1 - 1.8 8.6 6.7 0.093 12.8 0.5 1.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EDO04501.1 - 7 5.8 5.3 0.71 9.0 0.4 1.7 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2628 PF10947.3 EDO04501.1 - 7.3 6.4 12.9 1.3 8.8 6.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) TPR_11 PF13414.1 EDO04502.1 - 2.5e-20 71.8 26.4 2.5e-05 23.8 0.2 7.6 7 0 0 7 7 7 4 TPR repeat TPR_16 PF13432.1 EDO04502.1 - 2.2e-15 56.8 17.0 0.0004 20.9 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04502.1 - 1.3e-10 40.5 2.3 1.4 9.3 0.0 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04502.1 - 4.6e-09 35.4 15.0 0.04 13.6 0.1 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04502.1 - 7.6e-08 32.5 15.9 0.8 10.0 0.2 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04502.1 - 5.9e-06 26.1 24.9 0.025 14.4 0.3 7.3 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04502.1 - 6.3e-06 26.3 14.1 2.9 8.7 0.1 8.4 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDO04502.1 - 4.1e-05 23.6 10.3 1.5 8.9 0.0 6.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04502.1 - 0.00017 21.2 29.9 0.88 9.6 0.1 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDO04502.1 - 0.015 15.7 7.7 0.39 11.2 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04502.1 - 0.015 14.8 21.2 0.58 9.8 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04502.1 - 0.079 12.7 9.4 6.6 6.7 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EDO04502.1 - 0.11 11.8 6.4 2.7 7.3 0.2 3.3 3 1 0 3 3 3 0 26S proteasome subunit RPN7 DUF423 PF04241.10 EDO04502.1 - 0.87 9.5 2.1 13 5.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Sen15 PF09631.5 EDO04503.1 - 1.1e-26 92.9 0.0 2.1e-26 92.1 0.0 1.5 1 1 0 1 1 1 1 Sen15 protein Yippee-Mis18 PF03226.9 EDO04504.1 - 4.6e-23 81.0 0.2 5.2e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EDO04504.1 - 0.003 17.5 0.4 0.063 13.2 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 EDO04504.1 - 0.014 15.3 0.8 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Endonuclease_7 PF02945.10 EDO04504.1 - 0.016 14.8 1.1 0.026 14.2 0.8 1.6 1 1 0 1 1 1 0 Recombination endonuclease VII DUF3268 PF11672.3 EDO04504.1 - 0.078 13.0 1.3 0.83 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) zf-CHY PF05495.7 EDO04504.1 - 0.12 12.5 0.9 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger Evr1_Alr PF04777.8 EDO04504.1 - 0.14 12.0 0.5 3.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Ferric_reduct PF01794.14 EDO04505.1 - 3.5e-21 75.5 11.8 3.5e-21 75.5 8.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDO04505.1 - 1.4e-19 70.5 0.0 1.5e-16 60.6 0.0 2.9 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDO04505.1 - 1.3e-16 60.3 0.0 6.6e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain CLU PF13236.1 EDO04509.1 - 1.5e-82 276.3 0.0 2.7e-82 275.4 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EDO04509.1 - 9.5e-50 168.8 0.0 3.8e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EDO04509.1 - 1e-26 92.8 0.6 4.7e-26 90.7 0.1 2.4 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EDO04509.1 - 1.7e-25 88.7 19.7 2.9e-10 39.9 0.2 3.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EDO04509.1 - 8.5e-16 57.3 5.2 3.2e-05 23.7 0.1 4.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO04509.1 - 2.1e-06 27.2 9.3 0.0011 18.5 0.0 3.8 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EDO04509.1 - 4.2e-05 23.1 7.4 0.55 10.2 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04509.1 - 0.00094 18.7 4.3 0.24 11.2 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04509.1 - 0.005 16.3 1.7 2.9 7.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 EDO04509.1 - 0.0072 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_16 PF13432.1 EDO04509.1 - 0.019 15.6 0.5 36 5.2 0.0 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04509.1 - 0.091 13.0 2.0 1.3e+02 3.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04509.1 - 0.17 11.7 4.5 2.8 7.9 0.0 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Nuc_sug_transp PF04142.10 EDO04510.1 - 2e-09 36.9 0.6 2e-09 36.9 0.4 2.1 3 0 0 3 3 3 1 Nucleotide-sugar transporter TPT PF03151.11 EDO04510.1 - 1.6e-07 31.1 18.7 0.00071 19.2 2.4 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EDO04510.1 - 3.5e-07 29.4 6.3 5.7e-07 28.7 4.1 1.4 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EDO04510.1 - 1.3e-05 25.1 29.4 0.0002 21.3 3.8 3.4 3 1 1 4 4 4 2 EamA-like transporter family TrbC PF04956.8 EDO04510.1 - 0.0075 16.2 11.2 0.11 12.4 2.3 3.4 3 0 0 3 3 3 2 TrbC/VIRB2 family DUF914 PF06027.7 EDO04510.1 - 0.75 8.5 21.0 4.6 5.9 7.7 3.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) zf-C2H2_4 PF13894.1 EDO04513.1 - 3.2e-07 30.2 12.9 0.00084 19.5 2.3 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO04513.1 - 4.3e-06 26.7 12.4 0.003 17.8 1.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO04513.1 - 0.00094 19.3 9.8 0.84 10.0 0.3 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 EDO04513.1 - 1.3 9.2 6.0 0.14 12.3 0.7 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Calpain_III PF01067.17 EDO04514.1 - 1.3e-18 67.0 0.0 2.8e-17 62.7 0.0 2.7 2 1 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EDO04514.1 - 1.6e-16 60.2 0.0 2.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EDO04514.1 - 0.0007 19.4 1.4 0.0012 18.6 1.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain 7TMR-DISMED2 PF07696.6 EDO04514.1 - 0.081 12.3 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Mito_carr PF00153.22 EDO04515.1 - 2.7e-54 180.8 1.6 1.6e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.12 EDO04516.1 - 9.8e-23 79.7 9.9 1.5e-22 79.1 6.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.12 EDO04517.1 - 7.5e-11 41.7 0.1 1.4e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDO04517.1 - 1.1e-06 28.7 0.2 3e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2985 PF11204.3 EDO04518.1 - 9.3e-39 131.0 1.1 9.3e-39 131.0 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) Peptidase_C12 PF01088.16 EDO04519.1 - 4.3e-55 186.1 0.0 7.4e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Zn_clus PF00172.13 EDO04520.1 - 4.5e-08 32.8 14.0 6.8e-08 32.2 9.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDO04520.1 - 2.8e-07 29.4 0.5 5.1e-07 28.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain YqzE PF14038.1 EDO04521.1 - 0.027 14.2 0.5 0.046 13.4 0.3 1.4 1 0 0 1 1 1 0 YqzE-like protein HEAT PF02985.17 EDO04525.1 - 1.5e-24 83.8 4.3 4.8e-05 23.0 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EDO04525.1 - 1.5e-22 79.4 6.3 1.5e-13 50.7 0.0 7.1 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EDO04525.1 - 2.8e-18 65.9 0.1 4e-07 30.2 0.0 4.7 3 2 2 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO04525.1 - 1.2e-08 35.2 0.0 0.047 14.0 0.0 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EDO04525.1 - 0.00034 19.4 0.3 3.1 6.4 0.0 3.9 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Arm PF00514.18 EDO04525.1 - 0.0006 19.5 0.5 0.48 10.3 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EDO04525.1 - 0.002 17.5 0.1 3.8 6.7 0.0 4.0 6 0 0 6 6 6 2 CLASP N terminal Adaptin_N PF01602.15 EDO04525.1 - 0.0023 16.3 0.0 4.5 5.4 0.0 3.2 2 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 EDO04525.1 - 0.0028 17.5 0.1 11 5.8 0.0 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 PS_Dcarbxylase PF02666.10 EDO04527.1 - 6e-83 277.0 0.0 3.7e-81 271.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase K_oxygenase PF13434.1 EDO04528.1 - 7.7e-14 51.3 0.0 7.1e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDO04528.1 - 4.6e-12 46.4 0.0 1.8e-05 24.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO04528.1 - 2.7e-07 29.8 0.5 0.15 10.9 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDO04528.1 - 1.3e-05 25.0 0.0 0.039 13.7 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO04528.1 - 0.0001 22.6 0.4 0.063 13.7 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO04528.1 - 0.00025 20.2 0.2 0.023 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO04528.1 - 0.00049 20.0 0.0 0.58 10.0 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDO04528.1 - 0.00063 19.8 0.1 0.056 13.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EDO04528.1 - 0.0027 17.6 1.3 0.38 10.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDO04528.1 - 0.0045 15.9 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_10 PF13460.1 EDO04528.1 - 0.04 13.9 0.7 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 NADH(P)-binding FAD_binding_2 PF00890.19 EDO04528.1 - 0.057 12.2 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EDO04528.1 - 0.088 11.8 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EDO04528.1 - 0.34 10.5 0.8 2.8 7.5 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2407 PF10302.4 EDO04529.1 - 7.4e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EDO04529.1 - 5.4e-05 22.4 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EDO04529.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Polysacc_synt_3 PF13440.1 EDO04529.1 - 0.02 14.3 1.1 0.029 13.8 0.7 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Vps39_2 PF10367.4 EDO04530.1 - 1.8e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EDO04530.1 - 0.17 11.9 0.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 EDO04531.1 - 2e-92 308.7 0.4 2e-92 308.7 0.3 3.5 2 1 0 2 2 2 1 CASP C terminal Tropomyosin_1 PF12718.2 EDO04531.1 - 0.016 15.0 52.2 0.58 10.0 1.9 5.4 4 1 1 5 5 5 0 Tropomyosin like IncA PF04156.9 EDO04531.1 - 0.26 10.8 0.0 0.26 10.8 0.0 5.2 3 1 1 5 5 5 0 IncA protein DUF3584 PF12128.3 EDO04531.1 - 0.34 8.1 41.6 1.3 6.3 0.5 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) SecD-TM1 PF13721.1 EDO04531.1 - 0.54 10.5 6.8 0.89 9.8 0.1 3.4 3 0 0 3 3 3 0 SecD export protein N-terminal TM region ATG16 PF08614.6 EDO04531.1 - 0.68 9.7 52.9 1.7 8.4 0.2 5.6 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EDO04531.1 - 3.2 6.8 26.7 0.065 12.4 0.6 4.8 3 1 2 6 6 6 0 Reovirus sigma C capsid protein Hemerythrin PF01814.18 EDO04531.1 - 3.7 7.6 6.6 1.1 9.4 0.1 3.2 4 1 0 4 4 4 0 Hemerythrin HHE cation binding domain TPR_MLP1_2 PF07926.7 EDO04531.1 - 3.8 7.2 49.1 0.35 10.5 2.9 6.1 4 3 1 5 5 5 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EDO04531.1 - 4.5 7.0 25.3 0.48 10.2 0.1 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) DUF3455 PF11937.3 EDO04532.1 - 5.7e-51 173.0 0.2 8.4e-51 172.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) TPR_11 PF13414.1 EDO04533.1 - 3.9e-20 71.2 19.6 7.7e-09 35.0 0.0 9.0 7 3 4 11 11 11 6 TPR repeat TPR_1 PF00515.23 EDO04533.1 - 1.2e-15 56.3 16.1 0.0012 18.3 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04533.1 - 1.3e-15 55.9 28.0 0.0051 16.6 0.1 10.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04533.1 - 4.8e-13 48.8 24.3 1.4e-05 24.9 0.0 9.1 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04533.1 - 2.6e-11 42.4 12.9 0.015 14.9 0.0 8.7 10 1 1 11 11 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04533.1 - 2.6e-10 40.5 15.9 0.00013 22.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO04533.1 - 9e-06 26.2 39.4 0.0016 19.0 0.4 9.4 9 2 2 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04533.1 - 2e-05 24.7 25.9 0.15 12.7 0.0 10.3 9 2 1 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04533.1 - 0.00021 20.8 18.0 0.24 11.2 0.1 8.2 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04533.1 - 0.00027 20.9 6.0 5.3 7.5 0.0 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_3 PF07720.7 EDO04533.1 - 0.00048 19.8 14.2 0.032 14.0 0.3 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDO04533.1 - 0.00085 19.1 18.2 0.0081 16.0 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO04533.1 - 0.0013 18.7 14.3 0.67 10.1 0.0 6.7 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO04533.1 - 0.0034 17.7 25.7 4.6 7.9 0.0 10.0 12 0 0 12 12 9 2 Tetratricopeptide repeat PTS_IIA PF02255.11 EDO04533.1 - 0.23 11.3 0.1 0.23 11.3 0.0 3.3 3 1 1 4 4 3 0 PTS system, Lactose/Cellobiose specific IIA subunit SNF2_N PF00176.18 EDO04534.1 - 3.9e-83 278.6 0.9 3.9e-83 278.6 0.6 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EDO04534.1 - 5.2e-21 74.3 0.7 1.5e-20 72.8 0.5 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EDO04534.1 - 8.4e-18 64.0 0.1 1e-16 60.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EDO04534.1 - 5.8e-17 61.6 1.2 5.8e-17 61.6 0.8 3.7 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EDO04534.1 - 3.3e-16 58.8 10.9 3.3e-16 58.8 7.6 3.3 3 0 0 3 3 3 1 HSA QLQ PF08880.6 EDO04534.1 - 6.8e-13 47.7 1.1 6.8e-13 47.7 0.8 2.2 2 0 0 2 2 2 1 QLQ Peptidase_S41 PF03572.13 EDO04536.1 - 1.4e-08 34.2 0.0 4.6e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 His_Phos_2 PF00328.17 EDO04539.1 - 5e-29 101.7 0.0 6.2e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EDO04539.1 - 3.5e-05 23.9 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3233 PF11557.3 EDO04539.1 - 0.0054 15.6 0.0 0.0097 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3233) DCP1 PF06058.8 EDO04540.1 - 7.3e-17 61.5 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Kelch_3 PF13415.1 EDO04540.1 - 0.031 14.4 0.3 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Exo_endo_phos PF03372.18 EDO04541.1 - 4.7e-16 59.4 0.1 1.1e-15 58.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EDO04541.1 - 0.0095 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain HC2 PF07382.6 EDO04542.1 - 5.4e-06 26.4 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF3039 PF11238.3 EDO04545.1 - 0.0084 15.5 0.2 0.03 13.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3039) zf-DHHC PF01529.15 EDO04545.1 - 0.035 13.4 6.2 0.044 13.1 4.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Peptidase_C74 PF12387.3 EDO04545.1 - 0.11 11.6 2.1 0.11 11.6 1.5 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase TAP42 PF04177.7 EDO04546.1 - 0.15 11.0 1.1 0.82 8.5 0.0 2.0 1 1 0 2 2 2 0 TAP42-like family zf-DHHC PF01529.15 EDO04548.1 - 0.0047 16.3 0.2 0.0049 16.2 0.2 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase BAR PF03114.13 EDO04550.1 - 1e-49 169.1 12.3 1.2e-49 168.8 8.5 1.1 1 0 0 1 1 1 1 BAR domain RmuC PF02646.11 EDO04550.1 - 0.25 10.1 8.0 1.7 7.3 0.3 2.2 2 0 0 2 2 2 0 RmuC family DUF1501 PF07394.7 EDO04550.1 - 2.5 6.8 5.3 3.3 6.4 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1501) DUF342 PF03961.8 EDO04550.1 - 2.6 6.3 6.0 3.7 5.8 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EDO04550.1 - 4 6.3 16.1 3.4 6.6 8.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Pentapeptide_2 PF01469.13 EDO04552.1 - 8.2e-09 34.9 11.3 0.00028 20.4 0.1 4.0 2 2 1 3 3 3 3 Pentapeptide repeats (8 copies) gp32 PF08804.5 EDO04552.1 - 0.11 12.6 0.4 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 gp32 DNA binding protein like CITED PF04487.7 EDO04552.1 - 1.4 9.1 6.1 1.9 8.6 4.2 1.2 1 0 0 1 1 1 0 CITED Glyco_hydro_28 PF00295.12 EDO04556.1 - 1.6e-20 73.3 4.2 2.2e-20 72.8 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EDO04556.1 - 2.2e-05 24.6 11.4 5.9e-05 23.2 7.5 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF3293 PF11697.3 EDO04557.1 - 0.031 14.3 1.8 0.035 14.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Bot1p PF12298.3 EDO04557.1 - 0.11 12.3 2.1 0.14 12.1 1.5 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Dicer_dimer PF03368.9 EDO04557.1 - 0.13 12.1 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Dicer dimerisation domain DUF3043 PF11241.3 EDO04557.1 - 0.99 8.9 7.3 1.8 8.1 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Wbp11 PF09429.5 EDO04557.1 - 3.8 7.5 11.3 0.22 11.5 1.0 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 BAR PF03114.13 EDO04558.1 - 4.8e-62 209.4 4.5 5.9e-62 209.1 3.1 1.1 1 0 0 1 1 1 1 BAR domain MARVEL PF01284.18 EDO04559.1 - 7.6e-18 64.7 12.3 1.8e-17 63.5 8.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF3180 PF11377.3 EDO04559.1 - 0.045 13.6 0.0 0.045 13.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) OSTbeta PF15048.1 EDO04559.1 - 0.15 12.1 0.3 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein PrgI PF12666.2 EDO04559.1 - 4.5 7.4 13.8 0.2 11.7 0.4 2.8 2 1 1 3 3 3 0 PrgI family protein Pept_tRNA_hydro PF01195.14 EDO04560.1 - 7.2e-33 113.6 0.0 1.1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Corona_nucleoca PF00937.13 EDO04560.1 - 0.61 8.9 7.9 0.84 8.5 5.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ytp1 PF10355.4 EDO04561.1 - 4.3e-87 291.7 13.1 4.3e-87 291.7 9.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDO04561.1 - 1.6e-32 111.1 2.4 1.6e-32 111.1 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF3592 PF12158.3 EDO04561.1 - 0.0076 16.0 0.0 3.1 7.5 0.0 3.9 3 2 0 3 3 3 1 Protein of unknown function (DUF3592) UQ_con PF00179.21 EDO04565.1 - 5.5e-41 139.2 0.0 7.4e-41 138.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EDO04565.1 - 2.1e-06 27.1 0.1 3.8e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EDO04565.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO04565.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RWD domain AAA PF00004.24 EDO04566.1 - 2.2e-41 141.1 0.0 3.7e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO04566.1 - 6.2e-07 29.6 0.2 0.00022 21.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDO04566.1 - 4.7e-06 26.6 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDO04566.1 - 1.1e-05 24.4 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EDO04566.1 - 2e-05 24.3 0.0 6.3e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO04566.1 - 0.0003 19.9 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDO04566.1 - 0.00037 20.5 0.8 0.0011 18.9 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.1 EDO04566.1 - 0.0013 18.6 0.7 0.0045 16.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO04566.1 - 0.0023 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO04566.1 - 0.0042 17.8 0.2 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDO04566.1 - 0.0057 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDO04566.1 - 0.0067 16.1 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EDO04566.1 - 0.0071 16.0 0.1 0.34 10.5 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.1 EDO04566.1 - 0.0094 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO04566.1 - 0.0094 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EDO04566.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EDO04566.1 - 0.014 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDO04566.1 - 0.02 14.3 1.5 0.27 10.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EDO04566.1 - 0.021 13.9 0.2 0.47 9.5 0.0 2.2 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 EDO04566.1 - 0.027 13.1 0.8 0.046 12.4 0.1 1.7 2 1 0 2 2 2 0 TIP49 C-terminus NB-ARC PF00931.17 EDO04566.1 - 0.038 12.8 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EDO04566.1 - 0.043 13.9 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EDO04566.1 - 0.055 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO04566.1 - 0.055 13.0 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO04566.1 - 0.077 12.2 0.4 0.21 10.7 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EDO04566.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EDO04566.1 - 0.15 12.3 0.5 0.83 9.9 0.3 2.3 1 1 0 1 1 1 0 ABC transporter Ank_2 PF12796.2 EDO04567.1 - 2.2e-50 168.9 10.7 1.8e-15 57.0 0.0 9.5 5 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04567.1 - 7.2e-48 158.0 11.8 1.1e-06 28.1 0.1 14.1 15 0 0 15 15 15 7 Ankyrin repeat Ank_4 PF13637.1 EDO04567.1 - 6.5e-34 115.7 4.6 4.4e-05 23.8 0.0 10.3 9 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO04567.1 - 9.1e-34 112.1 16.2 9.8e-05 22.2 0.1 14.5 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 EDO04567.1 - 1.5e-32 110.8 8.7 0.00045 20.3 0.0 11.1 11 1 1 12 12 12 6 Ankyrin repeats (many copies) Tim44 PF04280.10 EDO04567.1 - 0.0058 16.6 0.0 7.2 6.5 0.0 4.0 4 0 0 4 4 4 1 Tim44-like domain Pyr_redox_2 PF07992.9 EDO04567.1 - 0.033 14.0 0.5 0.085 12.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_23 PF13476.1 EDO04567.1 - 3.2 8.0 10.3 0.55 10.5 2.2 3.3 4 0 0 4 4 4 0 AAA domain ATP-synt_DE_N PF02823.11 EDO04572.1 - 1.9e-20 72.3 0.1 2.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.4 EDO04575.1 - 8.3e-190 631.3 27.9 8.3e-190 631.3 19.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) NAD_binding_10 PF13460.1 EDO04576.1 - 2.1e-07 31.1 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Peptidase_M20 PF01546.23 EDO04576.1 - 0.026 14.0 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 FAD_binding_3 PF01494.14 EDO04577.1 - 2.3e-09 36.7 0.2 1.8e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EDO04577.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SE PF08491.5 EDO04577.1 - 0.022 13.6 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase DUF2685 PF10886.3 EDO04581.1 - 0.043 13.8 0.2 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Swi5 PF07061.6 EDO04582.1 - 5.5e-31 106.1 1.2 1.6e-30 104.6 0.4 2.3 2 0 0 2 2 2 1 Swi5 eIF-6 PF01912.13 EDO04583.1 - 2.2e-83 278.2 1.7 2.8e-83 277.8 1.2 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EDO04583.1 - 0.082 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Phage holin family 6 Claudin_2 PF13903.1 EDO04589.1 - 0.75 9.4 11.3 1.4 8.6 2.3 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction XPC-binding PF09280.6 EDO04590.1 - 2e-23 81.5 13.0 4.1e-23 80.5 9.0 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EDO04590.1 - 1e-18 66.4 0.3 1.7e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EDO04590.1 - 2e-13 49.7 5.6 1.7e-08 34.0 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EDO04590.1 - 8.6e-09 34.9 0.3 1.5e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EDO04590.1 - 0.0031 17.9 0.0 0.0065 16.9 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EDO04590.1 - 0.0059 16.1 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EDO04590.1 - 0.0083 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO04590.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF3295 PF11702.3 EDO04590.1 - 0.54 9.1 5.8 0.68 8.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HTH_Tnp_Tc5 PF03221.11 EDO04592.1 - 1.2e-13 50.6 0.0 4.8e-13 48.7 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO04592.1 - 6.4e-13 48.3 0.1 1.6e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04592.1 - 1.9e-10 40.1 0.0 3.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EDO04592.1 - 0.002 17.9 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 NUMOD1 domain HTH_23 PF13384.1 EDO04592.1 - 0.033 13.8 0.1 1.5 8.5 0.0 2.7 1 1 1 2 2 2 0 Homeodomain-like domain PRP38_assoc PF12871.2 EDO04594.1 - 0.077 13.5 46.8 0.084 13.4 32.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EDO04594.1 - 0.13 11.9 44.2 0.14 11.8 30.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DDE_1 PF03184.14 EDO04596.1 - 1.5e-50 171.3 0.0 3.3e-50 170.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04596.1 - 2.4e-10 39.7 0.7 1.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO04596.1 - 1.2e-07 31.3 0.1 5.6e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDO04596.1 - 8.9e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EDO04596.1 - 0.022 14.6 7.3 0.048 13.6 5.1 1.6 1 0 0 1 1 1 0 Zinc knuckle NUMOD1 PF07453.8 EDO04596.1 - 0.073 12.9 0.2 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 NUMOD1 domain rve PF00665.21 EDO04598.1 - 4.6e-20 71.9 0.0 6.5e-19 68.1 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDO04598.1 - 2.5e-18 66.2 0.0 4.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EDO04598.1 - 3e-10 40.0 0.4 8e-10 38.6 0.3 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EDO04598.1 - 1.6e-08 34.1 0.0 4.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDO04598.1 - 7e-07 29.6 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EDO04598.1 - 2e-06 27.4 1.1 4.9e-06 26.2 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.5 EDO04598.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 EDO04598.1 - 0.089 12.2 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Cas_CXXC_CXXC PF09706.5 EDO04599.1 - 0.0098 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_CXXC_CXXC) DUF716 PF04819.7 EDO04599.1 - 0.023 14.1 2.2 0.029 13.8 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF716) Aminotran_3 PF00202.16 EDO04600.1 - 5e-99 331.3 0.0 6.1e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDO04600.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_Tnp_Tc5 PF03221.11 EDO04601.1 - 1.4e-07 31.1 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDO04601.1 - 0.062 12.4 0.1 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF3404 PF11884.3 EDO04601.1 - 0.11 11.4 0.1 0.45 9.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3404) AT_hook PF02178.14 EDO04602.1 - 2 8.3 12.9 0.14 11.9 1.3 2.9 2 0 0 2 2 2 0 AT hook motif SRI PF08236.6 EDO04606.1 - 2.6e-22 78.5 10.8 8e-22 77.0 7.5 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EDO04606.1 - 4.8e-22 78.9 0.3 4.8e-22 78.9 0.2 3.4 2 2 0 2 2 2 1 SET domain WW PF00397.21 EDO04606.1 - 4.4e-06 26.4 1.5 9.4e-06 25.3 1.0 1.6 1 0 0 1 1 1 1 WW domain Zn_clus PF00172.13 EDO04608.1 - 0.00017 21.4 8.1 0.00035 20.4 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EDO04610.1 - 3e-17 63.2 0.1 4.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO04610.1 - 1e-06 28.5 0.1 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1350 PF07082.6 EDO04610.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.2 EDO04613.1 - 7.3e-21 75.0 0.0 9.3e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO04613.1 - 4.1e-06 26.6 0.0 7.6e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Carn_acyltransf PF00755.15 EDO04615.1 - 4.1e-96 322.3 0.0 5.7e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 EDO04615.1 - 7.1e-74 248.4 0.0 1.5e-73 247.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EDO04615.1 - 3.3e-54 184.3 0.0 5.8e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EDO04615.1 - 5.1e-44 150.6 0.0 1.8e-43 148.7 0.0 1.9 2 1 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EDO04615.1 - 1.3e-33 115.3 0.1 3.5e-33 113.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EDO04615.1 - 3.9e-13 49.7 0.0 1.9e-12 47.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO04615.1 - 8.7e-09 35.2 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EDO04615.1 - 1e-06 28.3 0.0 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EDO04615.1 - 2.5e-06 27.1 0.0 1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO04615.1 - 3e-05 24.5 0.0 8.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO04615.1 - 9.4e-05 22.8 0.0 0.00025 21.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO04615.1 - 0.00071 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF211 PF02680.9 EDO04615.1 - 0.03 14.1 0.1 11 5.9 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 ADH_N PF08240.7 EDO04615.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EDO04615.1 - 0.082 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site ERG4_ERG24 PF01222.12 EDO04616.1 - 2.6e-164 546.8 3.2 3e-164 546.6 2.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EDO04616.1 - 0.0043 16.3 0.6 0.012 14.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Iso_dh PF00180.15 EDO04619.1 - 4.6e-131 436.9 0.0 5.5e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 EDO04620.1 - 1.1e-09 37.8 7.6 1.7e-09 37.2 5.3 1.3 1 0 0 1 1 1 1 PHD-finger DUF4245 PF14030.1 EDO04620.1 - 0.098 12.3 0.2 6.8 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) MFS_1 PF07690.11 EDO04628.1 - 1.2e-19 70.2 20.5 6.5e-10 38.2 2.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EDO04628.1 - 0.0032 15.9 6.6 0.0071 14.7 0.5 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EDO04628.1 - 0.0034 17.1 4.9 8.3 6.2 0.0 3.9 4 0 0 4 4 4 3 MFS_1 like family Aminotran_3 PF00202.16 EDO04633.1 - 2.7e-79 266.4 0.0 3.3e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Med10 PF09748.4 EDO04634.1 - 3.3e-41 140.1 0.0 3.9e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TelA PF05816.6 EDO04634.1 - 0.019 13.6 0.2 0.019 13.6 0.1 1.4 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Flagellin_N PF00669.15 EDO04634.1 - 0.18 11.6 0.9 0.29 10.9 0.2 1.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Methyltransf_18 PF12847.2 EDO04635.1 - 2.1e-10 41.1 0.0 6.2e-07 29.9 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EDO04635.1 - 3.6e-09 36.3 0.4 1.1e-08 34.7 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO04635.1 - 0.00044 20.2 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO04635.1 - 0.004 17.5 0.0 0.019 15.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF4366 PF14283.1 EDO04635.1 - 0.02 14.3 0.2 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3984 PF13136.1 EDO04635.1 - 0.02 14.1 1.2 0.031 13.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Methyltransf_23 PF13489.1 EDO04635.1 - 0.078 12.6 2.0 0.14 11.8 1.4 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EDO04635.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CENP-B_dimeris PF09026.5 EDO04635.1 - 1.3 9.2 7.5 3.2 8.0 5.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HEAT PF02985.17 EDO04636.1 - 1.8e-44 145.7 16.5 0.0028 17.5 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EDO04636.1 - 3.4e-31 107.3 4.9 7.6e-09 35.7 0.0 7.5 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO04636.1 - 1.9e-11 44.2 6.7 0.0027 18.0 0.1 8.0 4 1 5 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDO04636.1 - 2.6e-11 43.6 6.9 0.08 13.4 0.0 8.6 7 1 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 EDO04636.1 - 3.5e-07 28.9 7.4 9.3e-06 24.2 0.8 3.6 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 EDO04636.1 - 0.00037 19.9 1.9 0.39 10.0 0.0 4.4 2 2 3 5 5 5 2 CLASP N terminal DUF2435 PF10363.4 EDO04636.1 - 0.0016 18.2 3.6 2.9 7.8 0.1 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EDO04636.1 - 0.0019 17.2 0.3 0.033 13.1 0.1 2.7 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain SAM_MT PF04445.8 EDO04636.1 - 0.07 12.2 0.1 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase Arm PF00514.18 EDO04636.1 - 0.097 12.5 4.7 2.4 8.1 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MadL PF03817.8 EDO04636.1 - 0.11 12.3 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd1 PF12717.2 EDO04636.1 - 0.23 11.2 8.3 33 4.2 0.0 5.4 3 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EDO04636.1 - 0.34 9.1 5.2 0.71 8.0 0.1 2.8 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit B3_4 PF03483.12 EDO04637.1 - 1.4e-24 86.5 0.1 2.4e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EDO04637.1 - 1.8e-19 69.3 0.0 8.7e-15 54.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Myotub-related PF06602.9 EDO04638.1 - 9e-123 409.5 0.0 1.3e-122 409.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EDO04638.1 - 0.011 15.9 0.1 0.038 14.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.15 EDO04639.1 - 2.8e-17 62.7 0.1 5.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EDO04639.1 - 2.6e-12 46.0 0.1 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EDO04639.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 EDO04640.1 - 1.6e-71 240.7 9.2 1.7e-59 201.2 1.2 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EDO04640.1 - 2.4e-07 30.9 3.0 2.4e-07 30.9 2.1 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EDO04640.1 - 0.00024 21.1 6.2 0.00024 21.1 4.3 3.1 2 1 0 2 2 2 1 EamA-like transporter family DUF2937 PF11157.3 EDO04640.1 - 0.24 10.7 0.7 0.49 9.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4257 PF14074.1 EDO04640.1 - 0.44 10.2 3.7 0.32 10.6 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4257) AgrB PF04647.10 EDO04640.1 - 1.2 8.1 13.7 2.6 7.0 0.0 3.2 2 1 2 4 4 4 0 Accessory gene regulator B NfeD PF01957.13 EDO04640.1 - 2.4 8.2 10.4 7.5 6.6 0.0 2.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Adap_comp_sub PF00928.16 EDO04642.1 - 4.2e-15 55.5 0.0 7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO04642.1 - 6.4e-07 29.1 0.3 1.1e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NPCBM PF08305.6 EDO04642.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 NPCBM/NEW2 domain Apc4 PF12896.2 EDO04643.1 - 5.4e-63 212.0 0.3 1.2e-62 210.9 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EDO04643.1 - 2.7e-19 68.3 0.0 2.8e-16 58.7 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EDO04643.1 - 3.6e-05 23.4 0.3 0.052 13.4 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat AA_permease_2 PF13520.1 EDO04644.1 - 8.1e-30 103.6 50.9 3e-28 98.5 35.3 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO04644.1 - 3.1e-12 45.6 45.1 3.2e-10 38.9 31.3 2.8 1 1 0 1 1 1 1 Amino acid permease Ku PF02735.11 EDO04645.1 - 2.1e-26 92.5 0.0 5.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDO04645.1 - 1.9e-19 70.0 0.0 3.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EDO04645.1 - 9.5e-12 44.8 0.2 2.6e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.23 EDO04645.1 - 0.00093 18.9 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.1 EDO04646.1 - 2.3e-28 98.2 3.2 1.8e-27 95.3 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.6 EDO04646.1 - 0.0054 16.4 0.6 1.6 8.4 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1772) SMC_N PF02463.14 EDO04647.1 - 1.1e-53 181.6 22.7 5.3e-52 176.2 15.8 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO04647.1 - 1e-26 93.2 0.0 7.8e-26 90.4 0.0 2.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO04647.1 - 5.3e-10 39.7 0.7 8.1e-06 26.0 0.1 4.5 4 1 1 5 5 5 2 AAA domain AAA_23 PF13476.1 EDO04647.1 - 1.1e-09 38.9 20.8 1.1e-09 38.9 14.4 6.6 1 1 2 3 3 3 1 AAA domain AAA_29 PF13555.1 EDO04647.1 - 5.6e-09 35.4 0.0 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EDO04647.1 - 5.9e-08 32.2 20.2 0.004 16.3 1.9 5.1 4 1 0 5 5 5 4 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EDO04647.1 - 0.0033 17.3 0.0 0.018 14.9 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF2838 PF10998.3 EDO04648.1 - 2.2e-46 156.3 10.5 2.2e-46 156.3 7.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) HK97-gp10_like PF04883.7 EDO04648.1 - 0.031 15.2 1.5 0.071 14.0 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component AAA_27 PF13514.1 EDO04648.1 - 0.045 11.4 2.1 0.063 10.9 1.4 1.1 1 0 0 1 1 1 0 AAA domain Not3 PF04065.10 EDO04648.1 - 0.15 11.3 4.2 0.27 10.4 2.9 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Atg14 PF10186.4 EDO04648.1 - 0.18 10.7 2.6 0.33 9.8 1.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sugar_tr PF00083.19 EDO04649.1 - 1e-118 396.8 21.9 1.9e-118 395.8 15.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO04649.1 - 9e-29 100.2 56.4 3.7e-25 88.4 22.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDO04649.1 - 0.00013 20.5 29.3 0.01 14.2 7.1 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein zf-HC5HC2H_2 PF13832.1 EDO04650.1 - 6.7e-33 112.9 8.1 6.7e-33 112.9 5.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 EDO04650.1 - 4.5e-30 105.0 0.0 1.7e-29 103.1 0.0 2.0 1 1 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 EDO04650.1 - 1.1e-26 92.7 5.4 1.1e-26 92.7 3.7 3.2 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EDO04650.1 - 1.6e-14 52.9 2.2 1.6e-14 52.9 1.5 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EDO04650.1 - 1.7e-08 33.9 23.8 1.3e-07 31.1 7.1 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EDO04650.1 - 1.5 8.0 12.5 0.042 13.1 2.0 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EDO04650.1 - 1.8 8.6 21.9 0.028 14.4 3.6 2.7 2 0 0 2 2 2 0 RING-like domain ADH_N PF08240.7 EDO04652.1 - 6.6e-26 90.2 1.9 1e-25 89.5 1.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO04652.1 - 2.7e-19 68.9 0.1 2.5e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO04652.1 - 8.7e-05 21.7 0.1 0.00015 20.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain STE PF02200.11 EDO04653.1 - 2.4e-50 169.3 0.3 5e-50 168.2 0.2 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EDO04653.1 - 2.4e-11 43.2 12.1 3.6e-06 26.9 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO04653.1 - 1.3e-09 37.7 11.0 9.4e-05 22.4 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO04653.1 - 4.9e-08 32.8 4.4 4.9e-08 32.8 3.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDO04653.1 - 0.00013 21.7 0.8 0.00048 19.9 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO04653.1 - 0.0022 18.0 1.0 0.1 12.7 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EDO04653.1 - 0.043 13.8 0.2 0.099 12.6 0.2 1.6 1 0 0 1 1 1 0 zinc-finger zf-Di19 PF05605.7 EDO04653.1 - 0.2 11.8 3.3 0.43 10.7 2.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.3 EDO04654.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain adh_short PF00106.20 EDO04659.1 - 1.2e-19 70.8 0.0 1.3e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO04659.1 - 5.7e-12 45.9 0.0 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO04659.1 - 2.4e-10 40.3 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDO04659.1 - 0.0034 16.3 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDO04659.1 - 0.0072 16.3 0.0 0.23 11.4 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 EDO04660.1 - 3.2e-12 45.8 0.1 4.7e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO04660.1 - 5e-08 32.7 11.9 8.8e-08 31.9 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3281 PF11685.3 EDO04662.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) FAM47 PF14642.1 EDO04662.1 - 0.18 11.0 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 FAM47 family Glyco_hydro_3 PF00933.16 EDO04663.1 - 4e-94 314.9 0.1 6.4e-94 314.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDO04663.1 - 6.3e-57 192.7 1.0 3.5e-56 190.2 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDO04663.1 - 9.9e-15 54.2 0.0 2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2528 PF10800.3 EDO04663.1 - 0.0019 18.5 0.5 0.22 11.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2528) DDE_1 PF03184.14 EDO04664.1 - 4e-14 52.2 0.4 4.5e-13 48.8 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04664.1 - 3.6e-09 36.0 0.0 6.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO04664.1 - 2.9e-08 33.3 0.3 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 EDO04664.1 - 0.011 15.8 0.1 0.024 14.7 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn helix DUF3404 PF11884.3 EDO04664.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) HTH_28 PF13518.1 EDO04664.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 EDO04664.1 - 0.14 12.0 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NUMOD1 domain RVT_1 PF00078.22 EDO04665.1 - 1.7e-05 24.3 0.0 0.00058 19.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) NACHT PF05729.7 EDO04667.1 - 4.8e-24 84.8 0.1 7.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain HET PF06985.6 EDO04667.1 - 4.7e-22 78.6 10.6 3.5e-20 72.5 5.3 3.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.1 EDO04667.1 - 1.3e-05 25.2 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EDO04667.1 - 0.0091 15.5 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EDO04667.1 - 0.012 14.4 0.1 0.045 12.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 EDO04667.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EDO04667.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EDO04667.1 - 0.031 14.4 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EDO04667.1 - 0.036 13.0 0.1 0.14 11.0 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EDO04667.1 - 0.095 12.8 0.1 0.53 10.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EDO04667.1 - 0.21 10.5 1.0 1.6 7.6 0.3 2.4 2 1 1 3 3 3 0 KAP family P-loop domain DUF3435 PF11917.3 EDO04668.1 - 5.2e-07 28.7 0.6 0.00024 19.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) RIO1 PF01163.17 EDO04669.1 - 0.0092 15.3 0.4 0.016 14.5 0.0 1.5 1 1 0 2 2 2 1 RIO1 family APH PF01636.18 EDO04669.1 - 0.01 15.6 0.4 0.017 14.8 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1374 PF07118.6 EDO04675.1 - 0.13 12.4 1.3 0.21 11.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) DUF4283 PF14111.1 EDO04676.1 - 0.11 11.6 0.1 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) DUF2062 PF09835.4 EDO04678.1 - 0.11 12.0 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Glyco_hydro_3 PF00933.16 EDO04679.1 - 3.3e-92 308.6 0.0 4.7e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDO04679.1 - 1.9e-52 178.0 0.1 2.5e-51 174.3 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDO04679.1 - 5.6e-21 74.2 0.2 1.1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain EB1 PF03271.12 EDO04681.1 - 6.2e-17 61.3 1.0 1.3e-16 60.3 0.7 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EDO04681.1 - 7.3e-07 29.2 1.6 1.2e-06 28.4 1.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 EDO04681.1 - 0.07 11.8 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain PX PF00787.19 EDO04682.1 - 2.3e-16 59.5 0.0 3.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EDO04682.1 - 1.3e-10 40.8 4.1 2.7e-10 39.7 2.9 1.6 1 0 0 1 1 1 1 SNARE domain Ank_2 PF12796.2 EDO04684.1 - 7.1e-86 282.6 10.3 6.7e-21 74.4 0.2 6.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04684.1 - 2.3e-69 225.9 9.3 6.1e-08 32.0 0.0 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EDO04684.1 - 1e-65 217.0 15.2 1.3e-12 47.8 0.0 9.6 4 1 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO04684.1 - 7.9e-55 181.6 12.0 3.1e-11 43.1 0.2 10.2 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO04684.1 - 3.4e-51 166.0 13.7 3.7e-05 23.5 0.0 10.4 10 0 0 10 10 10 9 Ankyrin repeat Cloacin_immun PF03513.9 EDO04684.1 - 0.0029 17.6 0.2 25 4.9 0.0 4.6 3 1 1 4 4 4 0 Cloacin immunity protein YfmQ PF10787.4 EDO04684.1 - 0.0099 15.2 0.6 9 5.6 0.0 4.7 2 1 2 6 6 6 1 Uncharacterised protein from bacillus cereus group HTH_22 PF13309.1 EDO04684.1 - 0.047 13.4 0.0 27 4.6 0.0 4.8 6 0 0 6 6 6 0 HTH domain C1_3 PF07649.7 EDO04684.1 - 4.8 7.3 10.9 11 6.1 7.5 1.6 1 0 0 1 1 1 0 C1-like domain TMC PF07810.8 EDO04685.1 - 0.013 15.8 0.1 0.035 14.5 0.1 1.7 1 0 0 1 1 1 0 TMC domain zf-DHHC PF01529.15 EDO04685.1 - 0.13 11.6 5.5 0.084 12.2 1.8 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase SdpI PF13630.1 EDO04685.1 - 1.4 8.7 4.5 2.8 7.7 3.1 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family PGAP1 PF07819.8 EDO04686.1 - 3.1e-08 33.4 0.8 8.4e-08 32.0 0.5 1.7 1 1 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 EDO04686.1 - 9e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EDO04686.1 - 0.00045 19.5 0.0 0.0028 16.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDO04686.1 - 0.0041 17.0 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_19 PF13245.1 EDO04686.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Neil1-DNA_bind PF09292.5 EDO04686.1 - 0.017 14.9 0.5 1.4 8.7 0.4 3.0 2 1 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind Lipase_3 PF01764.20 EDO04686.1 - 0.046 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 EDO04686.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 EDO04687.1 - 1.2e-99 322.9 17.1 4.1e-16 58.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Gmad1 PF10647.4 EDO04687.1 - 2.8e-11 43.3 13.4 0.00097 18.6 4.2 4.6 1 1 3 4 4 4 4 Lipoprotein LpqB beta-propeller domain DUF1258 PF06869.7 EDO04687.1 - 4.3e-10 39.1 0.2 0.4 9.7 0.0 5.7 1 1 5 6 6 6 3 Protein of unknown function (DUF1258) Nup160 PF11715.3 EDO04687.1 - 7.4e-10 37.5 4.3 0.078 11.1 0.1 5.4 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PD40 PF07676.7 EDO04687.1 - 8e-09 34.9 7.0 11 5.7 0.0 6.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 EDO04687.1 - 5.8e-05 22.6 0.0 35 4.0 0.0 5.6 3 2 3 6 6 6 0 Protein of unknown function (DUF1652) Me-amine-dh_H PF06433.6 EDO04687.1 - 7.5e-05 21.5 0.0 2.4 6.7 0.0 3.3 1 1 2 4 4 4 3 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 EDO04687.1 - 0.00013 21.2 3.7 4.2 6.3 0.0 5.4 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EDO04687.1 - 0.00015 20.1 0.0 6.6 4.8 0.0 4.8 1 1 3 5 5 5 1 Protein of unknown function (DUF3312) NYD-SP28_assoc PF14775.1 EDO04687.1 - 0.00023 20.7 0.4 86 2.9 0.0 5.8 6 0 0 6 6 6 0 Sperm tail C-terminal domain Peptidase_S9_N PF02897.10 EDO04687.1 - 0.00045 18.9 2.6 8.5 4.8 0.0 4.9 1 1 4 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain TFIIIC_delta PF12657.2 EDO04687.1 - 0.00072 19.3 2.9 25 4.5 0.0 5.4 1 1 5 6 6 6 0 Transcription factor IIIC subunit delta N-term Cytochrom_D1 PF02239.11 EDO04687.1 - 0.00092 17.6 0.1 0.26 9.5 0.0 3.1 1 1 3 4 4 4 2 Cytochrome D1 heme domain ABM PF03992.11 EDO04687.1 - 0.032 14.2 0.0 3e+02 1.5 0.0 5.1 6 1 1 7 7 7 0 Antibiotic biosynthesis monooxygenase DUF3240 PF11582.3 EDO04687.1 - 0.049 13.5 0.2 93 3.0 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3240) PLD_C PF12357.3 EDO04687.1 - 0.12 11.8 0.1 1.5e+02 1.9 0.0 4.8 6 0 0 6 6 6 0 Phospholipase D C terminal Proteasome_A_N PF10584.4 EDO04687.1 - 5.5 6.4 13.4 1.9e+02 1.5 0.1 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Ank_4 PF13637.1 EDO04688.1 - 1e-12 48.2 0.0 6.5e-07 29.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO04688.1 - 5.1e-11 42.7 0.0 6.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04688.1 - 5.1e-08 32.3 0.0 4.9e-07 29.2 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EDO04688.1 - 2.1e-07 30.5 0.0 0.0006 19.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EDO04688.1 - 1.7e-06 28.0 0.0 5.3e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_FA PF12248.3 EDO04688.1 - 0.06 13.3 0.0 0.22 11.5 0.0 1.8 1 1 1 2 2 2 0 Farnesoic acid 0-methyl transferase TPR_12 PF13424.1 EDO04689.1 - 1.9e-08 34.0 0.3 2.8e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO04689.1 - 6.1e-07 29.1 0.4 0.00077 19.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04689.1 - 0.00097 18.7 1.4 0.9 9.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04689.1 - 0.0091 15.7 0.2 0.2 11.5 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04689.1 - 0.039 13.8 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04689.1 - 0.074 12.6 0.6 3 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDO04689.1 - 0.1 12.2 0.3 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 TPR repeat HET PF06985.6 EDO04690.1 - 6.9e-09 35.9 0.0 7.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RVT_1 PF00078.22 EDO04691.1 - 1.2e-35 122.8 0.6 2e-35 122.1 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO04691.1 - 1.6e-14 54.3 0.0 3.8e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EDO04691.1 - 0.0076 16.5 0.2 0.033 14.5 0.0 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Tox-REase-3 PF15647.1 EDO04693.1 - 0.048 13.4 0.3 0.054 13.3 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 RVT_1 PF00078.22 EDO04694.1 - 1.4e-34 119.3 1.6 2.8e-34 118.3 1.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO04694.1 - 7e-11 42.5 0.3 9.2e-10 38.9 0.1 2.9 2 1 0 2 2 2 1 RNase H GnsAB PF08178.6 EDO04694.1 - 0.009 15.6 0.4 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 GnsA/GnsB family DUF3245 PF11595.3 EDO04695.1 - 0.053 13.7 0.1 0.092 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Bd3614_N PF14442.1 EDO04695.1 - 0.065 13.2 0.2 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PGA2 PF07543.7 EDO04696.1 - 0.038 13.7 9.3 0.04 13.7 6.4 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 p450 PF00067.17 EDO04697.1 - 6.5e-64 216.1 0.0 8.8e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COPR5 PF15340.1 EDO04700.1 - 0.033 14.5 0.1 2 8.7 0.0 2.1 1 1 1 2 2 2 0 Cooperator of PRMT5 family Glyco_hydro_32N PF00251.15 EDO04701.1 - 7.5e-85 284.9 0.6 9e-85 284.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EDO04701.1 - 0.0041 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal WD40 PF00400.27 EDO04702.1 - 9.8e-36 120.3 8.8 2e-07 30.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO04702.1 - 3.7e-08 33.3 0.0 0.0015 18.2 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DnaJ PF00226.26 EDO04704.1 - 1.2e-07 31.3 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EDO04704.1 - 3.9e-07 29.9 0.2 5.5e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Pam16 Glucosamine_iso PF01182.15 EDO04705.1 - 1.8e-58 197.5 0.0 2.1e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.1 EDO04706.1 - 5.8e-15 55.0 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO04706.1 - 4.5e-12 45.5 0.0 1.1e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO04706.1 - 2.5e-07 31.3 0.0 5.4e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SET PF00856.23 EDO04707.1 - 0.00022 21.5 0.2 0.86 9.8 0.0 2.7 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 EDO04707.1 - 0.0094 15.8 0.9 0.0094 15.8 0.6 2.3 3 0 0 3 3 3 1 MYND finger TPR_11 PF13414.1 EDO04707.1 - 0.47 10.1 2.7 3 7.5 0.1 2.8 2 1 0 2 2 2 0 TPR repeat AAT PF03417.11 EDO04708.1 - 9.8e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EDO04708.1 - 1.7e-06 28.2 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GST_N_3 PF13417.1 EDO04712.1 - 9.2e-13 48.2 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDO04712.1 - 9e-12 45.0 0.0 2.8e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO04712.1 - 3.1e-11 43.1 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO04712.1 - 9.2e-11 41.4 0.0 1.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDO04712.1 - 4.4e-10 39.4 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDO04712.1 - 3.2e-07 30.7 0.0 5.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 EDO04713.1 - 2.3e-11 43.0 9.7 1.8e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EDO04713.1 - 2.4e-08 33.4 0.2 4.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EDO04713.1 - 6.7e-07 28.9 4.9 0.0006 19.4 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EDO04713.1 - 0.00015 21.3 0.2 0.00039 19.9 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EDO04713.1 - 0.0019 17.8 6.0 0.49 10.1 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EDO04713.1 - 0.0034 17.0 8.2 0.15 11.7 0.3 2.8 1 1 1 2 2 2 2 Zinc knuckle Reo_sigmaC PF04582.7 EDO04715.1 - 0.72 8.9 9.3 0.43 9.6 1.8 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein p450 PF00067.17 EDO04718.1 - 3.1e-19 68.8 0.0 4.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3535 PF12054.3 EDO04719.1 - 2e-150 501.2 0.8 8.2e-150 499.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EDO04719.1 - 1.4e-71 240.7 0.0 6.1e-71 238.6 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO04719.1 - 5.3e-14 51.8 0.0 1.3e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EDO04719.1 - 2.5e-08 34.1 0.4 0.47 10.8 0.0 3.7 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDO04719.1 - 1.3e-07 31.0 13.8 1.7 8.9 0.2 8.0 8 0 0 8 8 8 4 HEAT repeat CLASP_N PF12348.3 EDO04719.1 - 0.0064 15.8 0.1 5.9 6.1 0.0 3.4 2 2 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EDO04719.1 - 0.098 13.1 12.3 57 4.3 0.0 7.7 9 0 0 9 9 9 0 HEAT-like repeat Pkinase PF00069.20 EDO04720.1 - 1.2e-28 99.9 0.0 1.9e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04720.1 - 6.7e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO04720.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATPgrasp_YheCD PF14398.1 EDO04721.1 - 0.21 10.3 2.3 0.18 10.5 0.3 1.7 2 0 0 2 2 2 0 YheC/D like ATP-grasp His_leader PF08047.6 EDO04721.1 - 5.1 6.6 18.6 8.6 5.8 12.9 1.3 1 0 0 1 1 1 0 Histidine operon leader peptide Nnf1 PF03980.9 EDO04723.1 - 1.6e-22 79.5 0.5 2.9e-22 78.6 0.3 1.5 2 0 0 2 2 2 1 Nnf1 DMPK_coil PF08826.5 EDO04723.1 - 0.017 14.9 0.4 0.017 14.9 0.3 2.5 3 1 0 3 3 3 0 DMPK coiled coil domain like TPR_MLP1_2 PF07926.7 EDO04723.1 - 0.029 14.1 1.4 0.029 14.1 1.0 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EDO04723.1 - 0.094 12.6 5.5 0.43 10.4 2.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 EDO04723.1 - 0.096 12.7 4.6 0.44 10.6 0.9 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 EDO04723.1 - 0.12 12.7 3.2 0.19 12.1 0.5 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 EDO04723.1 - 0.13 11.8 6.0 0.066 12.8 2.8 1.5 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 EDO04723.1 - 0.22 11.0 4.4 0.84 9.1 1.9 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 EDO04723.1 - 1.9 8.3 8.8 0.21 11.4 3.2 1.5 2 0 0 2 2 2 0 Tropomyosin like YpzG PF14139.1 EDO04723.1 - 2.9 7.9 4.8 8.3 6.4 3.3 1.7 1 1 0 1 1 1 0 YpzG-like protein PH_9 PF15410.1 EDO04724.1 - 6.1e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain MFS_1 PF07690.11 EDO04727.1 - 3.5e-18 65.4 26.5 3.5e-18 65.4 18.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO04727.1 - 0.82 8.1 35.8 11 4.4 24.8 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Cytochrom_B561 PF03188.11 EDO04729.1 - 0.0022 17.8 9.0 0.0022 17.7 5.2 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4366 PF14283.1 EDO04729.1 - 0.074 12.4 0.0 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2427 PF10348.4 EDO04729.1 - 0.13 11.8 3.9 0.34 10.5 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Cytochrom_B_C PF00032.12 EDO04729.1 - 8.4 6.6 8.4 1.3 9.3 0.8 2.6 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD CcdA PF07362.7 EDO04730.1 - 0.052 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA NPR2 PF06218.6 EDO04732.1 - 0.049 12.3 0.1 0.052 12.2 0.1 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF4452 PF14618.1 EDO04732.1 - 0.076 12.8 0.5 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Rtt106 PF08512.7 EDO04733.1 - 3.7e-27 94.1 0.2 1.1e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.9 EDO04733.1 - 4.2e-26 91.6 0.4 7.8e-26 90.7 0.3 1.5 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) TPR_11 PF13414.1 EDO04735.1 - 4.4e-08 32.6 7.5 0.00035 20.1 0.2 5.1 4 2 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EDO04735.1 - 1.7e-05 24.6 1.2 0.0046 17.0 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04735.1 - 0.004 16.9 7.1 1.6 8.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO04735.1 - 0.0062 16.1 4.6 1.8 8.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat MMS19_C PF12460.3 EDO04735.1 - 0.024 13.3 1.5 0.13 10.9 0.0 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal TPR_6 PF13174.1 EDO04735.1 - 0.037 14.4 0.8 11 6.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04735.1 - 0.038 13.9 1.6 16 5.5 0.2 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04735.1 - 0.068 13.8 7.2 1.2 9.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04735.1 - 0.089 13.1 5.3 0.19 12.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO04735.1 - 0.61 10.8 11.7 0.15 12.8 2.4 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat NTF2 PF02136.15 EDO04736.1 - 2e-23 83.0 0.3 3.5e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EDO04736.1 - 8.9e-09 34.8 0.1 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO04736.1 - 1.7e-07 31.0 0.0 4.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO04736.1 - 4e-05 23.3 0.0 7.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO04736.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif PAT1 PF09770.4 EDO04736.1 - 3.7 5.6 20.6 4.8 5.3 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ring_hydroxyl_B PF00866.13 EDO04737.1 - 0.0082 15.8 0.7 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 Ring hydroxylating beta subunit zf-CCHC_3 PF13917.1 EDO04737.1 - 0.024 14.3 0.0 0.024 14.3 0.0 4.0 5 0 0 5 5 5 0 Zinc knuckle Tnp_P_element PF12017.3 EDO04737.1 - 0.2 10.8 4.8 0.079 12.1 1.3 1.8 2 0 0 2 2 2 0 Transposase protein adh_short PF00106.20 EDO04739.1 - 3.6e-20 72.5 0.0 4.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO04739.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO04739.1 - 1.3e-08 34.6 0.0 2.8e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDO04739.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EDO04739.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EDO04739.1 - 0.029 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3405 PF11885.3 EDO04739.1 - 0.066 11.4 0.0 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF3673 PF12425.3 EDO04741.1 - 0.21 11.4 6.1 1.1 9.2 0.7 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF3673) Septin PF00735.13 EDO04742.1 - 1.3e-21 76.8 0.0 6.7e-21 74.5 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EDO04742.1 - 7.4e-05 22.6 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO04742.1 - 0.00034 21.1 0.1 0.00084 19.8 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EDO04742.1 - 0.0014 17.8 0.1 0.0051 16.0 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDO04742.1 - 0.0034 17.6 0.0 0.0092 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EDO04742.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family AAA_24 PF13479.1 EDO04742.1 - 0.0049 16.4 0.1 0.026 14.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EDO04742.1 - 0.0058 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 EDO04742.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 EDO04742.1 - 0.017 15.0 1.0 0.045 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MCM PF00493.18 EDO04742.1 - 0.02 13.6 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA PF00004.24 EDO04742.1 - 0.034 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EDO04742.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EDO04742.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EDO04742.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EDO04742.1 - 0.07 13.2 0.4 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EDO04742.1 - 0.085 12.5 0.1 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EDO04742.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EDO04742.1 - 0.089 11.7 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EDO04742.1 - 0.097 12.9 0.0 0.58 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDO04742.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDO04742.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EDO04742.1 - 0.2 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.20 EDO04743.1 - 7e-76 254.7 0.0 8.1e-76 254.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO04743.1 - 1.1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO04743.1 - 0.0072 15.3 0.1 0.35 9.7 0.0 2.9 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 EDO04743.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO04743.1 - 0.067 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EDO04745.1 - 6.7e-38 130.3 13.1 8.6e-38 129.9 9.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO04745.1 - 2.6e-15 55.9 5.6 4e-15 55.3 3.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDO04745.1 - 7.8e-08 30.9 2.8 1e-07 30.6 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDO04745.1 - 0.0076 14.3 3.1 0.72 7.8 0.0 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family PsaL PF02605.10 EDO04745.1 - 0.025 14.0 0.6 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI DUF3328 PF11807.3 EDO04746.1 - 2.3e-33 115.7 0.4 3e-33 115.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_31 PF13847.1 EDO04748.1 - 1.2e-09 37.9 0.0 2.8e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO04748.1 - 2.4e-08 33.8 0.0 4.2e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO04748.1 - 2.7e-07 31.1 0.0 7.1e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO04748.1 - 3.9e-06 27.2 0.0 8.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO04748.1 - 0.00034 20.6 0.0 0.00098 19.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO04748.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EDO04748.1 - 0.022 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 EDO04748.1 - 0.026 14.8 0.0 0.083 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDO04748.1 - 0.1 11.6 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase BRCA-2_OB1 PF09103.5 EDO04749.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.8 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tetraspannin PF00335.15 EDO04749.1 - 0.75 9.0 8.2 1 8.5 5.7 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.4 EDO04751.1 - 0.00067 18.3 0.0 0.00089 17.9 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SKG6 PF08693.5 EDO04751.1 - 0.0029 16.8 0.4 0.0029 16.8 0.3 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EDO04751.1 - 0.0052 15.1 0.3 0.0072 14.6 0.2 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E VPEP PF07589.6 EDO04751.1 - 0.22 11.4 2.2 0.59 10.1 1.5 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Macoilin PF09726.4 EDO04751.1 - 1.2 7.3 7.0 1.5 6.9 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 EDO04751.1 - 6 4.6 15.3 8.1 4.1 10.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF566 PF04484.7 EDO04751.1 - 6.3 6.2 11.6 9.3 5.6 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2823 PF11034.3 EDO04754.1 - 1.4e-31 108.3 4.0 1.6e-31 108.2 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) LRR_1 PF00560.28 EDO04755.1 - 6.6e-09 34.5 6.1 7.3 7.0 0.0 7.7 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.2 EDO04755.1 - 9.5e-08 31.5 1.1 0.4 10.3 0.0 5.6 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EDO04755.1 - 5.7e-05 22.7 13.2 5.7 7.3 0.0 9.3 10 1 0 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 EDO04755.1 - 0.0034 17.3 13.8 22 5.8 0.0 7.4 8 1 1 9 9 9 0 Leucine rich repeat CbbQ_C PF08406.5 EDO04755.1 - 0.072 13.0 0.2 39 4.3 0.0 3.6 4 0 0 4 4 4 0 CbbQ/NirQ/NorQ C-terminal Vir_act_alpha_C PF10400.4 EDO04755.1 - 0.1 12.9 0.0 0.83 10.0 0.0 2.3 1 1 1 2 2 2 0 Virulence activator alpha C-term Ste50p-SAM PF09235.5 EDO04755.1 - 0.36 10.8 9.5 13 5.8 0.1 5.5 2 2 4 7 7 7 0 Ste50p, sterile alpha motif K167R PF08065.7 EDO04756.1 - 0.051 13.6 0.1 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 K167R (NUC007) repeat DUF559 PF04480.7 EDO04756.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF559) RVT_1 PF00078.22 EDO04757.1 - 8.8e-12 44.8 0.1 2e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0150 PF03681.10 EDO04758.1 - 0.031 13.8 0.0 0.074 12.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) Chalcone PF02431.10 EDO04759.1 - 1.2e-62 210.8 0.0 1.7e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EDO04760.1 - 4.8e-20 71.2 0.2 7.3e-20 70.7 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.1 EDO04760.1 - 0.00042 19.8 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 EDO04760.1 - 0.00052 19.7 0.0 0.0007 19.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EDO04760.1 - 0.00073 19.7 0.4 0.0013 18.9 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EDO04760.1 - 0.0025 17.4 0.1 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 EDO04760.1 - 0.0033 17.6 0.2 0.0042 17.3 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 EDO04760.1 - 0.0044 16.6 0.3 0.019 14.5 0.1 1.9 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EDO04760.1 - 0.014 15.4 1.2 0.28 11.1 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Zn_ribbon_2 PF12674.2 EDO04760.1 - 0.02 15.2 0.4 0.028 14.7 0.1 1.5 2 1 0 2 2 2 0 Putative zinc ribbon domain Thioredoxin_9 PF14595.1 EDO04760.1 - 0.086 12.4 0.1 0.14 11.6 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin BAG PF02179.11 EDO04761.1 - 1.3e-18 66.8 2.5 5.1e-18 64.9 0.0 2.7 3 0 0 3 3 3 1 BAG domain Ribosomal_L13 PF00572.13 EDO04762.1 - 5.1e-28 97.6 0.5 7.5e-28 97.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 EDO04762.1 - 0.042 13.3 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AMP-binding PF00501.23 EDO04763.1 - 1.1e-66 225.0 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO04763.1 - 3.6e-16 59.8 0.1 6.7e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.7 EDO04764.1 - 0.0085 16.5 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SAP PF02037.22 EDO04768.1 - 1.5e-13 49.9 0.2 3.8e-13 48.5 0.1 1.8 1 0 0 1 1 1 1 SAP domain Armet PF10208.4 EDO04768.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding HeH PF12949.2 EDO04768.1 - 0.056 12.9 0.3 0.13 11.8 0.2 1.7 1 1 0 1 1 1 0 HeH/LEM domain Packaging_FI PF14000.1 EDO04768.1 - 0.51 10.5 5.3 0.13 12.4 0.8 2.1 2 0 0 2 2 2 0 DNA packaging protein FI His_Phos_1 PF00300.17 EDO04769.1 - 2.6e-10 40.5 0.0 1.4e-08 34.9 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Xan_ur_permease PF00860.15 EDO04774.1 - 3.3e-28 98.2 32.2 3.3e-28 98.2 22.3 1.7 2 0 0 2 2 2 1 Permease family Cytochrom_B_C PF00032.12 EDO04777.1 - 0.16 12.1 1.3 0.44 10.7 0.7 1.9 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF3632 PF12311.3 EDO04778.1 - 1.6e-41 142.1 6.7 2.4e-41 141.5 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HEAT PF02985.17 EDO04778.1 - 0.084 12.9 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat DUF4237 PF14021.1 EDO04779.1 - 5.2e-30 103.5 0.1 1.7e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4237) Nnf1 PF03980.9 EDO04780.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Nnf1 DUF4268 PF14088.1 EDO04781.1 - 0.064 12.9 1.2 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) DUF2722 PF10846.3 EDO04781.1 - 1.3 7.9 3.2 2 7.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MFS_1 PF07690.11 EDO04783.1 - 4.2e-34 117.7 18.5 4.2e-34 117.7 12.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amino_oxidase PF01593.19 EDO04784.1 - 1.5e-52 179.2 0.0 7.2e-37 127.5 0.0 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDO04784.1 - 3.8e-13 49.2 0.2 9e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EDO04784.1 - 7.1e-06 25.2 1.5 1.1e-05 24.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDO04784.1 - 2.5e-05 23.3 0.1 8.3e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDO04784.1 - 0.00014 21.4 0.4 0.0003 20.3 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EDO04784.1 - 0.00016 22.0 2.2 0.00037 20.8 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO04784.1 - 0.00037 19.4 0.5 0.00075 18.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDO04784.1 - 0.00066 18.8 0.3 0.0016 17.5 0.2 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EDO04784.1 - 0.0012 18.7 0.1 0.0038 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO04784.1 - 0.0057 16.7 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO04784.1 - 0.017 13.9 1.0 0.043 12.6 0.4 2.0 2 1 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EDO04784.1 - 0.018 13.5 0.7 0.039 12.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EDO04784.1 - 0.02 15.1 0.1 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EDO04784.1 - 0.091 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EDO04784.1 - 0.26 11.1 0.8 0.77 9.5 0.6 1.8 1 0 0 1 1 1 0 ThiF family Pro-kuma_activ PF09286.6 EDO04785.1 - 1.6e-48 164.4 0.1 3.6e-48 163.2 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDO04785.1 - 8.2e-05 21.8 0.2 0.00013 21.1 0.2 1.3 1 0 0 1 1 1 1 Subtilase family DDE_1 PF03184.14 EDO04786.1 - 3.4e-14 52.4 0.0 5.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04786.1 - 4.9e-09 35.8 0.1 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF904 PF06005.7 EDO04787.1 - 0.001 19.3 1.2 0.0022 18.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) zf-CCHC PF00098.18 EDO04787.1 - 0.0024 17.7 6.0 0.0036 17.1 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Herpes_BLRF2 PF05812.7 EDO04787.1 - 0.017 14.9 4.2 3.8 7.3 0.4 2.9 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EDO04787.1 - 0.019 14.9 1.3 0.03 14.2 0.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 EDO04787.1 - 0.04 14.2 0.4 0.057 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Peptidase_C2 PF00648.16 EDO04789.1 - 9.5e-56 188.9 0.2 4.8e-37 127.5 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease RR_TM4-6 PF06459.7 EDO04789.1 - 3.9 7.2 6.6 6.5 6.5 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mur_ligase_M PF08245.7 EDO04790.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Pyr_redox_3 PF13738.1 EDO04793.1 - 2.2e-12 47.4 0.0 1.6e-07 31.5 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO04793.1 - 1.6e-07 31.2 0.0 5e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO04793.1 - 5.1e-05 22.3 0.0 0.22 10.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDO04793.1 - 0.00018 21.3 0.1 0.035 13.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 EDO04793.1 - 0.00031 19.7 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EDO04793.1 - 0.0004 20.3 0.0 0.54 10.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO04793.1 - 0.00057 18.8 0.2 0.27 10.0 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.14 EDO04793.1 - 0.0029 15.8 0.2 1.1 7.3 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EDO04793.1 - 0.013 15.9 0.7 0.37 11.2 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDO04793.1 - 0.039 13.5 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EDO04793.1 - 0.1 12.7 0.8 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EDO04793.1 - 0.18 10.8 0.3 3 6.8 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.9 EDO04795.1 - 5.8e-12 44.9 0.2 0.0002 20.1 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase FAD_binding_3 PF01494.14 EDO04795.1 - 0.00049 19.2 0.2 0.081 11.9 0.2 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDO04795.1 - 0.0047 15.8 0.0 1.3 7.8 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EDO04795.1 - 0.06 12.4 0.2 0.94 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-ribbon_3 PF13248.1 EDO04795.1 - 0.15 11.3 4.2 0.097 11.9 1.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain His_Phos_2 PF00328.17 EDO04797.1 - 4e-16 59.2 0.0 8.4e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EDO04797.1 - 0.0019 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_2 PF00891.13 EDO04799.1 - 5.7e-33 114.1 0.0 6.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EDO04799.1 - 6.4e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDO04799.1 - 3.8e-05 23.1 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EDO04799.1 - 0.00026 21.5 0.0 0.00059 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EDO04799.1 - 0.00035 19.9 0.0 0.0008 18.7 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.1 EDO04799.1 - 0.0016 18.0 0.0 0.0088 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO04799.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2305 PF10230.4 EDO04800.1 - 1.6e-54 185.1 0.0 1.8e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EDO04800.1 - 0.00027 20.8 0.0 0.00044 20.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EDO04800.1 - 0.0031 16.8 0.0 0.0058 15.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EDO04800.1 - 0.0044 16.7 0.0 0.0095 15.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDO04800.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.3 EDO04800.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LCAT PF02450.10 EDO04800.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2207 PF09972.4 EDO04801.1 - 0.5 8.8 4.5 0.53 8.8 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1289 PF06945.8 EDO04802.1 - 0.037 13.4 2.9 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) HMG_box_2 PF09011.5 EDO04802.1 - 0.048 14.0 4.2 5.2 7.5 0.0 2.6 2 1 0 2 2 2 0 HMG-box domain Aldedh PF00171.17 EDO04802.1 - 0.061 11.6 0.2 0.2 9.9 0.0 1.7 2 0 0 2 2 2 0 Aldehyde dehydrogenase family HMG_box_5 PF14887.1 EDO04802.1 - 0.067 12.9 4.6 0.18 11.5 0.3 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF3997 PF13162.1 EDO04802.1 - 0.12 12.2 3.3 0.075 12.8 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3997) ABC_membrane PF00664.18 EDO04804.1 - 4.4e-98 328.0 38.5 2.4e-49 168.1 7.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO04804.1 - 3.5e-69 231.4 0.3 2.4e-33 115.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EDO04804.1 - 1.7e-14 53.5 0.0 4.5e-05 22.8 0.0 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO04804.1 - 3.7e-10 40.2 0.4 0.086 12.7 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDO04804.1 - 1.3e-08 34.2 0.6 0.0004 19.8 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EDO04804.1 - 2.1e-08 33.2 2.8 0.0079 14.8 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EDO04804.1 - 1.9e-07 31.2 1.5 0.018 15.0 0.1 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EDO04804.1 - 4.5e-07 30.6 0.0 0.033 14.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EDO04804.1 - 6.9e-07 28.5 0.0 0.2 10.8 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO04804.1 - 1.2e-05 25.4 0.8 0.56 10.3 0.2 4.1 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EDO04804.1 - 1.2e-05 24.7 0.1 0.12 11.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EDO04804.1 - 0.00019 21.2 2.9 0.65 9.9 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EDO04804.1 - 0.00043 20.1 1.4 0.41 10.4 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EDO04804.1 - 0.0021 18.3 2.3 1.3 9.3 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EDO04804.1 - 0.0037 17.2 1.1 0.48 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EDO04804.1 - 0.0041 16.5 2.6 11 5.3 0.1 4.5 5 0 0 5 5 5 0 AAA-like domain AAA_33 PF13671.1 EDO04804.1 - 0.0044 16.9 0.0 2.8 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO04804.1 - 0.0059 16.1 5.8 1.1 8.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EDO04804.1 - 0.014 15.2 0.0 4.7 7.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.9 EDO04804.1 - 0.022 14.4 0.5 12 5.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EDO04804.1 - 0.035 13.5 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 EDO04804.1 - 0.043 12.5 0.1 7.4 5.1 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit PRK PF00485.13 EDO04804.1 - 0.059 12.9 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EDO04804.1 - 0.34 11.2 7.9 1.8 8.8 0.0 3.8 4 0 0 4 4 3 0 AAA domain VirB3 PF05101.8 EDO04804.1 - 1.1 9.2 17.0 4 7.4 0.0 5.3 5 0 0 5 5 5 0 Type IV secretory pathway, VirB3-like protein Actin PF00022.14 EDO04805.1 - 4e-26 91.3 0.0 8.2e-17 60.6 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EDO04805.1 - 0.0042 15.7 0.0 0.098 11.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Joubert PF15392.1 EDO04806.1 - 0.049 12.8 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated Neur PF00064.13 EDO04807.1 - 0.087 10.8 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase TauD PF02668.11 EDO04808.1 - 8e-40 137.1 0.0 1.2e-39 136.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EDO04808.1 - 0.015 14.1 0.0 0.032 13.1 0.0 1.4 1 1 0 1 1 1 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 EDO04808.1 - 0.034 14.6 0.5 0.27 11.7 0.3 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.18 EDO04809.1 - 6e-06 25.8 0.1 2.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO04809.1 - 0.017 15.0 1.8 0.1 12.5 0.4 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF3504 PF12012.3 EDO04809.1 - 0.17 11.6 2.3 0.87 9.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3504) Amidohydro_2 PF04909.9 EDO04811.1 - 2.7e-43 148.4 0.0 3.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase CFEM PF05730.6 EDO04812.1 - 2.4e-13 49.7 17.4 4.6e-13 48.7 12.1 1.5 1 0 0 1 1 1 1 CFEM domain Herpes_UL32 PF06070.6 EDO04812.1 - 0.78 8.1 12.9 0.95 7.8 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Gag_spuma PF03276.9 EDO04812.1 - 4.5 5.4 9.5 5.3 5.2 6.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PBD PF00786.23 EDO04817.1 - 0.047 14.1 1.3 0.18 12.2 0.1 2.7 2 0 0 2 2 2 0 P21-Rho-binding domain DUF4632 PF15451.1 EDO04818.1 - 0.14 12.1 3.6 0.55 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) HSP90 PF00183.13 EDO04818.1 - 0.26 9.6 1.6 0.43 8.8 1.1 1.3 1 0 0 1 1 1 0 Hsp90 protein PPP4R2 PF09184.6 EDO04818.1 - 3.1 7.2 8.2 4.9 6.6 5.7 1.3 1 0 0 1 1 1 0 PPP4R2 LMBR1 PF04791.11 EDO04819.1 - 2.5e-28 98.9 4.7 3.4e-28 98.4 3.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PspA_IM30 PF04012.7 EDO04819.1 - 0.15 11.3 3.2 6.6 6.0 0.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family CorA PF01544.13 EDO04820.1 - 0.015 14.3 8.4 0.014 14.4 3.3 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CoA_binding_3 PF13727.1 EDO04820.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain EF-hand_6 PF13405.1 EDO04821.1 - 3.7e-12 45.0 1.4 2.8e-05 23.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EDO04821.1 - 7.4e-11 40.5 2.3 4.1e-05 22.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDO04821.1 - 6.2e-08 32.6 0.0 0.003 17.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EDO04821.1 - 4e-05 23.1 0.1 0.089 12.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDO04821.1 - 0.0002 20.5 9.7 0.0018 17.5 0.3 2.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EDO04821.1 - 0.033 14.0 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Afi1 PF07792.7 EDO04822.1 - 7.8e-65 217.3 0.0 1.4e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EDO04822.1 - 1.5e-37 127.7 0.0 2.9e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EDO04822.1 - 4.6e-07 28.6 0.0 0.023 13.1 0.0 3.3 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EDO04822.1 - 0.0098 15.1 0.0 0.34 10.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) Esterase PF00756.15 EDO04823.1 - 1.9e-51 174.9 0.0 2.3e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EDO04823.1 - 1.7e-05 24.5 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EDO04823.1 - 0.00017 20.9 0.0 0.00071 18.8 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EDO04823.1 - 0.0023 17.1 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDO04823.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EDO04823.1 - 0.02 13.7 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Tfb2 PF03849.9 EDO04823.1 - 0.14 10.7 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 RNA_pol_Rpb6 PF01192.17 EDO04824.1 - 4.2e-24 84.0 1.2 7e-24 83.3 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 EDO04825.1 - 2.5e-24 84.0 56.8 0.00016 21.8 0.1 10.6 10 1 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO04825.1 - 1.2e-19 69.0 49.2 0.0011 19.1 0.1 10.4 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO04825.1 - 6.3e-08 32.5 23.0 0.36 11.0 1.6 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO04825.1 - 1.1e-07 31.7 11.8 2.1 8.6 1.3 7.2 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EDO04825.1 - 1.9e-06 27.8 59.2 0.1 12.9 0.2 10.8 12 0 0 12 12 12 6 Zinc-finger double domain Whi5 PF08528.6 EDO04826.1 - 2.2e-10 39.8 0.4 3.9e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 Whi5 like Peptidase_M18 PF02127.10 EDO04829.1 - 7.9e-161 535.3 0.0 2.2e-160 533.9 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_transf_8 PF01501.15 EDO04830.1 - 1.3e-33 116.3 0.0 2.4e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDO04830.1 - 0.0019 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EDO04830.1 - 0.13 11.9 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Prp18 PF02840.10 EDO04833.1 - 4.4e-52 175.7 0.0 4.4e-52 175.7 0.0 2.6 3 1 1 4 4 4 1 Prp18 domain PRP4 PF08799.6 EDO04833.1 - 4.4e-11 41.8 0.8 4.4e-11 41.8 0.5 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EDO04833.1 - 0.77 8.9 24.4 1.2 8.2 16.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TROVE PF05731.6 EDO04833.1 - 0.85 8.3 13.1 1.1 7.9 9.1 1.2 1 0 0 1 1 1 0 TROVE domain Ycf1 PF05758.7 EDO04833.1 - 5.8 4.5 12.5 7.1 4.2 8.7 1.3 1 0 0 1 1 1 0 Ycf1 PRP1_N PF06424.7 EDO04833.1 - 8.3 6.7 18.9 23 5.2 13.1 1.7 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SAP18 PF06487.7 EDO04834.1 - 7.4e-05 22.5 0.0 8.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TraX PF05857.6 EDO04835.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 TraX protein GST_N_3 PF13417.1 EDO04836.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO04836.1 - 1.8e-08 34.2 0.1 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDO04836.1 - 5.2e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO04836.1 - 7.3e-06 25.8 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO04836.1 - 5.2e-05 23.0 0.0 9.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO04836.1 - 0.00016 22.0 0.0 0.00037 20.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Arf PF00025.16 EDO04837.1 - 9.4e-66 220.3 0.0 1.1e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDO04837.1 - 1e-10 40.9 0.3 3.3e-07 29.3 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EDO04837.1 - 1.9e-10 40.2 0.0 2.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EDO04837.1 - 2.3e-07 31.3 0.0 3.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO04837.1 - 1.1e-06 28.5 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EDO04837.1 - 1.5e-06 27.7 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EDO04837.1 - 1.1e-05 24.7 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO04837.1 - 0.045 13.1 0.0 1.4 8.3 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EDO04837.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3336 PF11815.3 EDO04838.1 - 2.5e-50 169.7 6.5 3.8e-50 169.1 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO04838.1 - 9e-20 71.4 0.2 4.6e-19 69.1 0.1 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Chromo PF00385.19 EDO04839.1 - 2e-21 75.4 9.3 2.3e-12 46.4 1.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EDO04839.1 - 3.4e-05 23.6 0.5 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 Polycomb-like MTF2 factor 2 Latrotoxin_C PF15658.1 EDO04839.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain HSDR_N_2 PF13588.1 EDO04840.1 - 0.033 13.9 0.0 2.2 8.0 0.1 2.8 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) GFO_IDH_MocA PF01408.17 EDO04842.1 - 1.3e-18 67.5 1.1 5.7e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDO04842.1 - 6e-15 55.0 0.0 9.9e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EDO04842.1 - 0.048 14.0 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EDO04842.1 - 0.09 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DDE_1 PF03184.14 EDO04844.1 - 3.8e-18 65.4 1.0 1e-17 63.9 0.0 2.1 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04844.1 - 1.4e-08 34.1 0.0 2.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO04844.1 - 9e-07 28.6 0.2 4.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 EDO04844.1 - 0.033 14.3 0.1 0.065 13.3 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.17 EDO04844.1 - 0.042 13.7 0.4 0.14 12.0 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix NUMOD1 PF07453.8 EDO04844.1 - 0.05 13.4 0.7 0.26 11.1 0.1 2.5 3 0 0 3 3 3 0 NUMOD1 domain HTH_28 PF13518.1 EDO04844.1 - 0.071 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_16 PF10294.4 EDO04845.1 - 1.2e-16 60.6 0.0 1.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDO04845.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO04845.1 - 0.00048 19.3 0.0 0.00067 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EDO04845.1 - 0.0027 17.1 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EDO04845.1 - 0.0066 15.4 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.1 EDO04845.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EDO04845.1 - 0.058 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 EDO04845.1 - 0.082 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2361 PF10153.4 EDO04846.1 - 2.2e-39 134.1 13.4 2.2e-39 134.1 9.3 2.3 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF3161 PF11362.3 EDO04846.1 - 0.12 12.3 0.5 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DUF3811 PF11656.3 EDO04846.1 - 5.1 7.2 12.0 0.22 11.6 3.6 2.3 2 1 0 2 2 2 0 YjbD family (DUF3811) WD40 PF00400.27 EDO04847.1 - 0.06 13.2 0.1 12 6.0 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Glyco_hydro_31 PF01055.21 EDO04848.1 - 9.4e-105 350.9 0.6 2.1e-104 349.8 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF3661 PF12400.3 EDO04850.1 - 0.09 12.8 2.2 0.11 12.5 1.5 1.1 1 0 0 1 1 1 0 Vaculolar membrane protein Xpo1 PF08389.7 EDO04851.1 - 4.3e-36 124.0 0.0 6.3e-34 117.0 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EDO04851.1 - 0.00042 20.1 0.1 14 6.1 0.0 5.4 4 1 1 5 5 5 1 HEAT repeat HalX PF08663.5 EDO04851.1 - 0.029 14.3 0.9 0.11 12.4 0.6 2.0 1 0 0 1 1 1 0 HalX domain TPR_11 PF13414.1 EDO04852.1 - 1.1e-45 153.1 22.9 6.9e-17 60.8 0.4 6.4 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 EDO04852.1 - 9.1e-32 107.3 22.1 5.6e-07 28.9 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EDO04852.1 - 8.2e-31 103.4 21.3 6.4e-07 28.8 0.1 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.26 EDO04852.1 - 5.2e-27 93.3 4.9 5.2e-27 93.3 3.4 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 EDO04852.1 - 7.3e-25 87.0 16.1 1.1e-06 29.1 0.1 6.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO04852.1 - 2.2e-22 79.1 21.6 3.3e-06 27.3 0.2 6.5 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDO04852.1 - 1.5e-19 68.7 20.1 2.4e-05 24.5 0.1 8.5 3 3 5 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EDO04852.1 - 1.2e-13 50.9 8.4 4.1e-06 26.8 0.5 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDO04852.1 - 2.6e-13 49.7 17.1 0.0076 16.1 3.2 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDO04852.1 - 2.4e-12 45.6 21.7 0.00062 19.3 0.0 8.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO04852.1 - 2.9e-12 45.7 17.1 0.12 12.6 0.4 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDO04852.1 - 6.9e-11 41.8 12.8 0.00031 20.5 0.4 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO04852.1 - 1e-08 34.3 12.4 0.094 12.5 0.2 7.8 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO04852.1 - 1.1e-07 31.7 22.6 0.018 15.4 0.1 8.7 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDO04852.1 - 4.1e-05 22.7 10.5 0.027 13.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EDO04852.1 - 0.0006 20.1 3.9 13 6.0 0.1 4.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 EDO04852.1 - 0.002 18.1 13.3 2.4 8.3 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat DUF928 PF06051.7 EDO04852.1 - 0.0022 17.6 0.6 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) SNAP PF14938.1 EDO04852.1 - 0.014 14.5 1.1 0.014 14.5 0.8 3.4 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP YfdX PF10938.3 EDO04852.1 - 0.041 13.5 6.5 0.58 9.8 0.0 3.8 3 0 0 3 3 3 0 YfdX protein DUF2225 PF09986.4 EDO04852.1 - 0.063 12.7 1.8 0.17 11.3 0.6 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 EDO04852.1 - 0.13 12.2 14.9 2 8.4 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDO04852.1 - 0.19 12.2 6.6 3.2 8.4 0.0 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO04852.1 - 1.3 8.9 16.7 0.52 10.2 0.2 5.2 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 EDO04852.1 - 1.8 7.9 7.4 31 3.9 0.1 4.4 5 0 0 5 5 5 0 SHNi-TPR FGGY_C PF02782.11 EDO04856.1 - 1.4e-25 90.0 0.0 3.4e-25 88.8 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDO04856.1 - 2.2e-16 59.9 0.0 1.3e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain GFO_IDH_MocA PF01408.17 EDO04856.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Cation_efflux PF01545.16 EDO04857.1 - 1.1e-57 195.2 0.4 1.3e-57 195.0 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family SIR2 PF02146.12 EDO04858.1 - 1.6e-33 115.8 0.0 3.1e-33 115.0 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Peptidase_C50 PF03568.12 EDO04859.1 - 4.5e-116 387.6 0.0 1.2e-115 386.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 EDO04859.1 - 7.4e-07 29.0 13.3 1.5e-06 27.9 0.9 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat CHAT PF12770.2 EDO04859.1 - 0.00048 19.3 0.0 0.0094 15.1 0.0 2.4 1 1 0 1 1 1 1 CHAT domain Man-6-P_recep PF02157.10 EDO04860.1 - 3.7e-12 45.8 0.0 5.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EDO04860.1 - 3.4e-08 33.3 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EDO04860.1 - 5.3e-05 22.5 0.4 5.3e-05 22.5 0.2 2.6 1 1 1 2 2 2 1 Autophagy-related protein 27 Nucleoplasmin PF03066.10 EDO04860.1 - 0.016 14.7 1.0 0.029 13.8 0.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EDO04860.1 - 0.032 14.5 4.2 0.032 14.5 2.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EDO04860.1 - 0.11 12.1 1.2 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PRKCSH_1 PF13015.1 EDO04860.1 - 0.12 11.7 0.3 0.42 10.0 0.0 2.0 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein CDC45 PF02724.9 EDO04860.1 - 0.14 10.1 0.9 0.18 9.7 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EDO04860.1 - 0.18 11.5 1.4 0.32 10.7 1.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 EDO04860.1 - 0.61 10.2 3.8 1.3 9.2 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.6 EDO04860.1 - 1.9 6.2 5.2 5.9 4.6 3.6 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen bZIP_1 PF00170.16 EDO04861.1 - 6.1e-06 26.1 7.8 1.1e-05 25.2 5.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.6 EDO04861.1 - 0.28 10.7 5.1 0.21 11.1 1.6 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Stm1_N PF09598.5 EDO04862.1 - 3.9e-18 65.9 1.5 3.9e-18 65.9 1.0 4.6 3 1 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EDO04862.1 - 1.7e-05 25.2 2.0 1.7e-05 25.2 1.4 2.3 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family PKI PF02827.11 EDO04862.1 - 3.6 7.7 7.1 0.68 10.0 1.5 2.4 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor PHD PF00628.24 EDO04863.1 - 1.3e-08 34.3 3.9 2.7e-08 33.3 2.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EDO04863.1 - 0.019 15.1 0.1 0.059 13.5 0.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EDO04863.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Pox_Ag35 PF03286.9 EDO04863.1 - 0.56 9.7 27.9 2.8 7.4 0.1 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein ING PF12998.2 EDO04864.1 - 0.00042 20.5 0.2 0.0025 18.0 0.0 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2_4 PF13894.1 EDO04866.1 - 1.9 9.0 8.4 0.068 13.5 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO04866.1 - 7.4 7.0 9.3 6.3 7.2 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EDO04866.1 - 9.1 6.8 12.3 0.15 12.4 2.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3602 PF12223.3 EDO04868.1 - 2.7e-18 66.1 24.7 2.1e-14 53.6 1.6 3.7 2 1 0 3 3 3 2 Protein of unknown function (DUF3602) SMN PF06003.7 EDO04868.1 - 0.0056 15.8 1.7 0.0084 15.2 1.2 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) zf-C2H2 PF00096.21 EDO04872.1 - 1e-06 28.7 18.6 1.7e-05 24.9 1.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO04872.1 - 4.7e-05 23.4 3.8 4.7e-05 23.4 2.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO04872.1 - 0.0011 19.1 0.9 0.0011 19.1 0.6 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO04872.1 - 0.0012 18.8 0.7 0.0033 17.5 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1199 PF06712.6 EDO04872.1 - 0.019 14.7 0.5 0.061 13.1 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) zf-TRAF PF02176.13 EDO04872.1 - 0.041 14.2 1.7 0.13 12.7 1.2 1.9 1 0 0 1 1 1 0 TRAF-type zinc finger SnoaL_2 PF12680.2 EDO04873.1 - 1.1e-05 25.8 0.6 3.9e-05 23.9 0.2 1.8 1 1 1 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.1 EDO04873.1 - 0.00099 19.0 0.2 0.0022 17.9 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EDO04873.1 - 0.024 14.8 0.3 0.032 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3225 PF11533.3 EDO04873.1 - 0.035 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) AhpC-TSA_2 PF13911.1 EDO04874.1 - 2.9e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Tubulin_3 PF14881.1 EDO04875.1 - 3.4e-76 254.7 0.1 9.8e-76 253.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EDO04875.1 - 9.7e-40 135.2 0.0 2e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EDO04875.1 - 1.9e-05 24.5 0.0 0.068 12.9 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Fork_head PF00250.13 EDO04877.1 - 3.3e-12 46.2 0.6 5.3e-12 45.6 0.3 1.5 2 0 0 2 2 2 1 Fork head domain HTH_Tnp_Tc5 PF03221.11 EDO04878.1 - 5.4e-09 35.7 0.1 9.3e-09 34.9 0.0 1.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Nol1_Nop2_Fmu PF01189.12 EDO04880.1 - 1.3e-15 57.5 0.0 4.8e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 NOL1/NOP2/sun family MFS_1 PF07690.11 EDO04881.1 - 1.5e-37 129.1 35.2 1.5e-37 129.1 24.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO04881.1 - 1.5e-09 36.9 13.1 3.5e-08 32.4 8.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3403 PF11883.3 EDO04885.1 - 0.023 14.9 0.3 0.036 14.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3403) DnaJ PF00226.26 EDO04887.1 - 2.8e-21 75.0 0.5 8.3e-21 73.4 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.14 EDO04888.1 - 7.9e-27 94.2 21.3 7.9e-27 94.2 14.8 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PLATZ PF04640.9 EDO04888.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 PLATZ transcription factor Adaptin_N PF01602.15 EDO04889.1 - 2.8e-144 481.3 0.2 3.5e-144 481.0 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EDO04889.1 - 8e-13 48.7 0.3 1.8e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EDO04889.1 - 4.8e-07 29.9 0.4 0.033 14.4 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EDO04889.1 - 0.00075 19.3 1.1 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EDO04889.1 - 0.0031 17.3 7.2 0.05 13.4 0.6 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EDO04889.1 - 0.0043 17.5 0.6 11 6.6 0.0 4.6 3 1 2 5 5 5 1 HEAT-like repeat TIP120 PF08623.5 EDO04889.1 - 0.0063 16.1 0.5 0.035 13.6 0.0 2.4 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 EDO04889.1 - 0.17 11.7 1.1 73 3.4 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4470 PF14737.1 EDO04890.1 - 2.9e-14 52.5 0.0 5.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EDO04890.1 - 0.00017 21.1 1.0 0.00031 20.3 0.2 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EDO04890.1 - 0.056 13.3 0.5 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO04890.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_psq PF05225.11 EDO04891.1 - 7.4e-14 51.0 0.6 1.7e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDO04891.1 - 5.3e-10 38.7 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_3 PF01381.17 EDO04891.1 - 0.00081 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix Shugoshin_N PF07558.6 EDO04891.1 - 0.012 15.3 1.8 0.021 14.5 0.1 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NUMOD1 PF07453.8 EDO04891.1 - 0.02 14.7 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain zf-FPG_IleRS PF06827.9 EDO04893.1 - 0.00047 19.7 1.4 0.44 10.2 0.0 2.3 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS zf-C2H2_4 PF13894.1 EDO04893.1 - 0.026 14.8 1.4 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TFIIB PF13453.1 EDO04893.1 - 0.061 12.5 0.3 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2688 PF10892.3 EDO04893.1 - 0.12 12.1 1.0 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) C1_1 PF00130.17 EDO04893.1 - 0.23 11.2 1.3 3 7.6 0.9 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Yippee-Mis18 PF03226.9 EDO04893.1 - 0.33 11.0 2.1 5 7.2 1.0 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SR-25 PF10500.4 EDO04893.1 - 0.42 10.0 10.0 0.46 9.9 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HMA PF00403.21 EDO04893.1 - 1.7 8.8 4.0 1 9.5 0.3 2.0 2 0 0 2 2 2 0 Heavy-metal-associated domain Metallophos PF00149.23 EDO04896.1 - 5.5e-07 29.1 0.3 0.00014 21.3 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO04896.1 - 0.0015 18.3 0.0 0.021 14.6 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SR-25 PF10500.4 EDO04898.1 - 0.023 14.1 16.0 0.03 13.8 11.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDRGK PF09756.4 EDO04898.1 - 0.95 8.8 23.6 0.58 9.5 7.6 2.1 2 0 0 2 2 2 0 DDRGK domain Moulting_cycle PF04870.11 EDO04898.1 - 3 6.8 9.7 2.8 6.9 0.4 2.1 2 0 0 2 2 2 0 Moulting cycle Apt1 PF10351.4 EDO04898.1 - 5.8 5.6 9.2 8.2 5.1 6.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MIP-T3 PF10243.4 EDO04898.1 - 6.8 5.0 22.9 10 4.4 15.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 EDO04898.1 - 7.2 6.1 6.9 4.5 6.8 3.6 1.4 1 1 0 1 1 1 0 IncA protein DDE_1 PF03184.14 EDO04900.1 - 4.1e-50 169.9 0.1 1.1e-49 168.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDO04900.1 - 5.5e-10 38.6 0.9 4.8e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDO04900.1 - 3.4e-07 29.9 0.0 1.4e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDO04900.1 - 0.021 14.7 7.3 0.048 13.6 5.1 1.7 1 0 0 1 1 1 0 Zinc knuckle SpoIIID PF12116.3 EDO04900.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D Flavin_Reduct PF01613.13 EDO04901.1 - 3.3e-27 95.2 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Vps5 PF09325.5 EDO04903.1 - 1.9e-87 292.4 1.9 3.1e-87 291.7 1.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EDO04903.1 - 4e-25 87.8 0.0 1.3e-24 86.1 0.0 2.0 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EDO04903.1 - 0.0095 15.2 0.4 0.027 13.7 0.2 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EDO04903.1 - 0.22 10.9 6.1 0.34 10.3 4.2 1.4 1 1 0 1 1 1 0 BAR domain Med11 PF10280.4 EDO04904.1 - 1.3e-37 128.4 0.1 1.7e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Myc_target_1 PF15179.1 EDO04904.1 - 0.088 12.3 0.3 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Myc target protein 1 WD40 PF00400.27 EDO04906.1 - 1.1e-55 183.6 26.5 1.3e-10 40.7 1.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EDO04906.1 - 1.9e-45 154.4 0.9 2.7e-45 153.9 0.6 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nucleoporin_N PF08801.6 EDO04906.1 - 4.6e-06 25.6 0.0 0.38 9.4 0.0 3.9 3 1 1 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 EDO04906.1 - 5.3e-05 23.0 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EDO04906.1 - 0.0049 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EDO04906.1 - 0.045 11.8 0.8 2.5 6.1 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 HSP90 PF00183.13 EDO04908.1 - 3.9e-255 847.2 34.0 4.7e-255 847.0 23.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EDO04908.1 - 7.8e-12 45.0 0.2 7.8e-12 45.0 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO04908.1 - 1.3e-11 44.2 0.1 2.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EDO04908.1 - 0.011 15.5 0.2 0.011 15.5 0.1 2.0 2 0 0 2 2 2 0 Tumour suppressor protein DUF1676 PF07898.8 EDO04908.1 - 0.18 12.1 0.2 0.18 12.1 0.1 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1676) Pectate_lyase_3 PF12708.2 EDO04910.1 - 4.4e-86 288.6 37.8 1.5e-70 237.8 5.7 3.6 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EDO04910.1 - 3.2e-08 32.9 3.1 0.0033 16.8 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ank_2 PF12796.2 EDO04912.1 - 0.0033 17.7 0.0 0.0039 17.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO04912.1 - 0.023 14.5 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 EDO04912.1 - 0.1 12.9 0.0 26 5.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat XH PF03469.9 EDO04914.1 - 0.018 14.6 1.2 0.018 14.6 0.8 2.6 1 1 2 3 3 3 0 XH domain FliT PF05400.8 EDO04914.1 - 0.09 13.1 4.6 0.21 12.0 3.2 1.7 1 0 0 1 1 1 0 Flagellar protein FliT Remorin_C PF03763.8 EDO04914.1 - 0.58 9.7 15.6 3.3 7.2 0.4 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region K_trans PF02705.11 EDO04915.1 - 1.5e-166 554.9 15.8 3.2e-125 418.5 10.0 2.1 1 1 1 2 2 2 2 K+ potassium transporter DUF485 PF04341.7 EDO04915.1 - 0.89 9.2 0.0 0.89 9.2 0.0 4.5 3 1 2 5 5 5 0 Protein of unknown function, DUF485 SPRY PF00622.23 EDO04916.1 - 8.4e-22 77.5 0.1 1.3e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain F-box PF00646.28 EDO04917.1 - 0.0037 16.8 2.6 0.0038 16.8 0.6 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EDO04917.1 - 0.024 14.3 2.7 0.026 14.2 0.6 2.0 3 0 0 3 3 3 0 F-box-like EBP PF05241.7 EDO04918.1 - 0.00012 21.1 8.4 0.00026 20.0 5.8 1.7 1 1 0 1 1 1 1 Emopamil binding protein Scs3p PF10261.4 EDO04919.1 - 1.3e-68 230.6 2.6 1.5e-68 230.3 1.8 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3921 PF13060.1 EDO04920.1 - 0.00031 20.5 23.3 7.6 6.5 0.1 7.7 4 4 4 8 8 8 6 Protein of unknown function (DUF3921) DUF3108 PF11306.3 EDO04920.1 - 0.0027 17.3 2.2 0.0027 17.3 1.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3108) RHS_repeat PF05593.9 EDO04920.1 - 0.012 15.7 26.3 1.3 9.3 0.1 8.0 5 4 1 6 6 6 0 RHS Repeat Ras PF00071.17 EDO04921.1 - 3.9e-57 192.1 0.0 4.6e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO04921.1 - 3.2e-19 69.5 0.0 4.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO04921.1 - 1.9e-13 50.0 0.0 2.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO04921.1 - 4.2e-06 26.0 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO04921.1 - 9.4e-06 25.1 0.0 2.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO04921.1 - 0.00032 20.6 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EDO04921.1 - 0.0055 16.7 0.0 0.0075 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO04921.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Kri1_C PF12936.2 EDO04922.1 - 2.9e-28 97.6 1.3 2.9e-28 97.6 0.9 4.1 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EDO04922.1 - 3.5e-28 97.8 22.6 3.5e-28 97.8 15.6 6.0 3 2 1 5 5 5 1 KRI1-like family Colicin PF01024.14 EDO04922.1 - 0.023 14.2 2.2 0.065 12.8 1.5 1.7 1 0 0 1 1 1 0 Colicin pore forming domain PH PF00169.24 EDO04923.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EDO04923.1 - 0.0011 18.4 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF3074 PF11274.3 EDO04925.1 - 1.3e-66 223.7 5.7 1.5e-66 223.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 EDO04925.1 - 2.1e-05 23.9 45.9 2.1e-05 23.9 31.8 2.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TPR_MLP1_2 PF07926.7 EDO04925.1 - 0.001 18.8 28.2 0.0024 17.6 19.6 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Abhydrolase_1 PF00561.15 EDO04926.1 - 3.9e-09 36.4 0.0 1.5e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO04926.1 - 2.4e-06 27.5 0.0 4.2e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Flavin_Reduct PF01613.13 EDO04927.1 - 3.6e-16 59.3 0.0 5.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 EDO04928.1 - 4.8e-53 180.2 0.0 5.8e-45 153.6 0.0 2.9 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EDO04928.1 - 0.022 14.3 0.0 0.065 12.7 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDO04928.1 - 0.056 13.0 3.2 0.6 9.7 2.3 2.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily AMP-binding PF00501.23 EDO04929.1 - 3e-55 187.2 0.6 3e-21 75.3 0.0 4.7 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EDO04929.1 - 0.00015 22.3 0.0 0.00041 20.9 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain Abhydrolase_6 PF12697.2 EDO04933.1 - 1.3e-05 25.2 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EDO04933.1 - 0.00085 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EDO04933.1 - 0.011 15.3 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EDO04933.1 - 0.099 11.9 0.0 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) APH PF01636.18 EDO04934.1 - 0.0081 15.9 0.0 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO04934.1 - 0.13 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2_6 PF13912.1 EDO04941.1 - 0.0015 18.3 0.6 0.082 12.8 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO04941.1 - 0.024 14.9 13.8 3.3 8.2 0.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO04941.1 - 0.038 14.2 8.1 0.29 11.4 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO04941.1 - 6.3 7.3 15.4 5 7.6 0.2 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-rbx1 PF12678.2 EDO04942.1 - 4.1e-11 42.8 1.0 7.7e-11 41.9 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDO04942.1 - 7.4e-10 38.4 6.8 6.2e-09 35.5 4.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO04942.1 - 2.2e-07 30.4 3.6 5.1e-06 26.0 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO04942.1 - 4.6e-06 26.2 1.5 1.6e-05 24.5 1.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO04942.1 - 6.5e-06 25.7 0.2 1.4e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO04942.1 - 8e-05 22.5 1.7 8e-05 22.5 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO04942.1 - 0.0091 15.6 4.0 0.051 13.3 2.8 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO04942.1 - 0.05 13.4 4.3 0.3 10.9 3.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EDO04942.1 - 0.06 13.2 1.2 0.13 12.1 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDO04942.1 - 0.54 9.8 3.1 0.24 10.9 0.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1936 PF09151.5 EDO04944.1 - 0.53 9.8 4.4 1.5 8.4 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1936) RNase_E_G PF10150.4 EDO04945.1 - 0.012 14.8 1.3 0.012 14.8 0.9 1.7 2 0 0 2 2 2 0 Ribonuclease E/G family IncA PF04156.9 EDO04945.1 - 0.022 14.3 9.8 0.16 11.5 1.2 2.2 2 0 0 2 2 2 0 IncA protein OmpH PF03938.9 EDO04945.1 - 0.05 13.5 4.0 0.16 11.9 0.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF484 PF04340.7 EDO04945.1 - 0.12 11.8 1.8 0.19 11.1 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF484 KLRAQ PF10205.4 EDO04945.1 - 0.14 12.2 6.1 0.47 10.5 3.5 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein HAUS-augmin3 PF14932.1 EDO04945.1 - 0.78 8.8 10.5 0.12 11.5 3.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1014 PF06244.7 EDO04945.1 - 2.6 8.2 6.6 0.59 10.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1014) DMPK_coil PF08826.5 EDO04945.1 - 2.9 7.8 11.3 0.54 10.1 0.1 3.4 4 0 0 4 4 4 0 DMPK coiled coil domain like Phage_int_SAM_5 PF13102.1 EDO04945.1 - 5.1 7.0 7.4 8.3 6.4 0.7 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain AAA_11 PF13086.1 EDO04946.1 - 5.2e-22 78.5 1.3 8.2e-22 77.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDO04946.1 - 4.7e-14 52.2 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO04946.1 - 2.3e-06 27.2 0.0 6.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDO04946.1 - 2.3e-05 24.0 0.0 0.012 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain zf-CCCH PF00642.19 EDO04946.1 - 0.00031 20.3 1.8 0.00055 19.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.4 EDO04946.1 - 0.0014 17.6 0.2 0.0039 16.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EDO04946.1 - 0.0027 17.7 0.3 0.021 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDO04946.1 - 0.033 15.0 0.0 0.22 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain FYVE PF01363.16 EDO04949.1 - 7.6e-16 57.7 6.9 1.2e-15 57.1 4.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EDO04949.1 - 2.4 8.0 14.3 0.25 11.2 6.5 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger Arf PF00025.16 EDO04950.1 - 1.1e-37 128.9 0.1 5.1e-25 87.7 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EDO04950.1 - 1.4e-12 47.0 0.1 3.3e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO04950.1 - 1.4e-09 37.4 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDO04950.1 - 1.5e-07 30.8 0.1 3.5e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO04950.1 - 2.1e-06 27.2 0.0 0.0016 17.8 0.0 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EDO04950.1 - 5.9e-06 26.7 0.0 8.3e-05 23.0 0.0 2.1 1 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EDO04950.1 - 3.3e-05 23.4 0.0 0.0002 20.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO04950.1 - 0.0003 20.7 0.0 0.00048 20.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RFX5_DNA_bdg PF14621.1 EDO04951.1 - 0.079 12.5 1.0 0.11 12.0 0.7 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain DUF2834 PF11196.3 EDO04951.1 - 0.084 13.0 0.3 0.084 13.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) AT_hook PF02178.14 EDO04951.1 - 1.9 8.3 6.1 4.2 7.3 4.3 1.6 1 0 0 1 1 1 0 AT hook motif GMC_oxred_N PF00732.14 EDO04953.1 - 9.2e-49 166.1 0.5 1.3e-48 165.6 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO04953.1 - 1.9e-24 86.5 0.0 4.5e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDO04953.1 - 5.5e-12 45.2 0.2 1.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO04953.1 - 9.6e-09 34.5 0.2 1.7e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDO04953.1 - 2.7e-08 33.7 0.8 4e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO04953.1 - 4.3e-07 30.0 0.2 1.6e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO04953.1 - 1.7e-06 27.2 0.2 1.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EDO04953.1 - 0.00023 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDO04953.1 - 0.0025 16.3 0.1 0.0043 15.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EDO04953.1 - 0.0082 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO04953.1 - 0.025 13.4 0.1 0.4 9.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EDO04953.1 - 0.059 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDO04953.1 - 0.21 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SNF2_N PF00176.18 EDO04955.1 - 3.2e-44 150.9 0.0 5.6e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO04955.1 - 1.7e-15 56.6 0.1 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GSH_synth_ATP PF03917.12 EDO04957.1 - 7e-116 386.8 0.0 8.5e-116 386.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EDO04957.1 - 2.5e-33 114.3 0.0 4.5e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.20 EDO04959.1 - 2e-17 62.9 0.1 2.4e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Bgal_small_N PF02929.12 EDO04963.1 - 0.12 11.3 0.9 0.12 11.3 0.6 1.0 1 0 0 1 1 1 0 Beta galactosidase small chain ESCRT-II PF05871.7 EDO04963.1 - 0.18 11.7 2.2 0.2 11.5 1.6 1.1 1 0 0 1 1 1 0 ESCRT-II complex subunit Borrelia_P83 PF05262.6 EDO04963.1 - 2.3 6.3 8.4 2.8 6.1 5.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_3_Rpc31 PF11705.3 EDO04964.1 - 0.28 11.1 9.2 0.29 11.0 6.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 S-antigen PF05756.6 EDO04964.1 - 0.3 11.0 6.2 0.33 10.9 4.3 1.1 1 0 0 1 1 1 0 S-antigen protein Myc_N PF01056.13 EDO04964.1 - 0.79 8.8 5.0 0.75 8.9 3.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.7 EDO04964.1 - 1.2 8.2 11.5 1.2 8.2 8.0 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FLO_LFY PF01698.11 EDO04964.1 - 1.2 7.9 8.2 1.3 7.8 5.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Pox_Ag35 PF03286.9 EDO04964.1 - 1.4 8.4 9.8 1.6 8.2 6.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.6 EDO04964.1 - 1.4 7.4 4.9 1.3 7.6 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2215 PF10225.4 EDO04964.1 - 1.8 7.9 6.1 1.9 7.8 4.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PGA2 PF07543.7 EDO04964.1 - 2.2 8.0 14.5 2.5 7.8 10.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 BTV_NS2 PF04514.7 EDO04964.1 - 2.5 6.8 10.9 2.7 6.7 7.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM176 PF14851.1 EDO04964.1 - 2.5 7.7 8.1 2.7 7.6 5.6 1.1 1 0 0 1 1 1 0 FAM176 family Adeno_terminal PF02459.10 EDO04964.1 - 3.7 5.5 9.8 4.2 5.4 6.8 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Vfa1 PF08432.5 EDO04964.1 - 7.1 6.6 14.3 7.2 6.5 9.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLTH PF10607.4 EDO04965.1 - 7.6e-34 116.4 0.0 1.2e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EDO04965.1 - 0.00019 21.0 0.1 0.00054 19.6 0.0 1.9 2 0 0 2 2 2 1 LisH DUF4206 PF13901.1 EDO04965.1 - 0.12 11.9 2.7 0.87 9.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) NICE-3 PF07406.6 EDO04965.1 - 0.15 11.5 1.7 0.13 11.7 0.2 1.5 2 0 0 2 2 2 0 NICE-3 protein Rtt106 PF08512.7 EDO04966.1 - 0.065 13.2 0.1 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone chaperone Rttp106-like HLH PF00010.21 EDO04967.1 - 1.9e-12 46.6 0.3 3.9e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EDO04967.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Tom22 PF04281.8 EDO04967.1 - 6.3 6.3 8.0 0.92 9.0 0.3 2.6 2 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 ABC_membrane PF00664.18 EDO04969.1 - 8.5e-70 235.2 19.7 2.3e-41 142.0 5.3 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EDO04969.1 - 8.2e-52 175.1 0.0 1.6e-30 106.1 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO04969.1 - 6.6e-10 38.5 2.9 0.0049 16.1 0.1 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDO04969.1 - 1.1e-07 32.0 0.5 0.02 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EDO04969.1 - 4.3e-06 26.6 0.0 0.086 12.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EDO04969.1 - 5.8e-06 26.4 0.3 0.11 12.4 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 EDO04969.1 - 8.2e-06 25.2 0.1 0.078 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO04969.1 - 2.7e-05 23.6 0.0 0.043 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EDO04969.1 - 2.8e-05 24.5 0.2 0.23 11.9 0.0 3.4 3 0 0 3 3 3 2 Miro-like protein DUF258 PF03193.11 EDO04969.1 - 0.00013 21.1 0.0 0.072 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDO04969.1 - 0.00026 21.4 6.7 0.011 16.0 1.3 3.6 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EDO04969.1 - 0.00043 20.1 1.7 0.064 13.0 0.0 3.0 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.13 EDO04969.1 - 0.00098 18.6 0.0 0.98 8.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.1 EDO04969.1 - 0.0011 18.5 0.9 1.1 8.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EDO04969.1 - 0.0028 16.5 0.0 0.29 9.9 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_17 PF13207.1 EDO04969.1 - 0.013 16.3 0.0 11 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDO04969.1 - 0.034 14.2 1.9 4.5 7.4 0.0 3.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDO04969.1 - 0.038 13.8 4.3 1 9.1 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EDO04969.1 - 0.052 12.6 0.5 12 4.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 EDO04969.1 - 0.059 13.5 0.0 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUP PF00674.13 EDO04969.1 - 0.061 13.2 0.2 0.29 11.1 0.1 2.2 1 0 0 1 1 1 0 DUP family GTP_EFTU PF00009.22 EDO04969.1 - 0.12 11.8 0.0 17 4.8 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ERM PF00769.14 EDO04969.1 - 0.15 11.5 4.5 0.15 11.5 0.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2841 PF11001.3 EDO04972.1 - 8.9e-40 135.4 1.6 1.7e-39 134.5 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3243 PF11588.3 EDO04972.1 - 0.14 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) p450 PF00067.17 EDO04974.1 - 5.8e-33 114.1 0.0 7.7e-31 107.1 0.0 2.9 1 1 0 1 1 1 1 Cytochrome P450 DUF2881 PF11087.3 EDO04975.1 - 0.074 12.5 0.0 17 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2881) DUF2830 PF11125.3 EDO04975.1 - 0.42 10.3 1.5 2.1 8.1 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2830) DUF1311 PF07007.7 EDO04975.1 - 0.92 9.6 4.4 27 4.9 0.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) EthD PF07110.6 EDO04976.1 - 2.4e-21 76.4 0.2 2.9e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 EthD domain HTH_psq PF05225.11 EDO04977.1 - 1.5e-13 50.0 0.1 3.1e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EDO04977.1 - 3.4e-11 42.6 0.6 1.6e-08 33.9 0.0 3.3 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04977.1 - 5.6e-07 29.2 0.0 6.9e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.17 EDO04977.1 - 0.00075 19.3 0.1 0.0045 16.7 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix DDE_3 PF13358.1 EDO04977.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease OmpH PF03938.9 EDO04978.1 - 0.16 11.9 1.0 0.28 11.1 0.7 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Abhydrolase_3 PF07859.8 EDO04979.1 - 1.3e-36 126.1 0.0 1.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EDO04979.1 - 0.0095 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.23 EDO04979.1 - 0.012 14.3 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family STE3 PF02076.10 EDO04980.1 - 1.6e-29 102.9 22.0 2.3e-17 63.0 3.8 2.2 1 1 1 2 2 2 2 Pheromone A receptor FAD-oxidase_C PF02913.14 EDO04982.1 - 3.8e-46 157.4 0.0 5e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDO04982.1 - 4.8e-12 45.5 0.0 9.1e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EDO04982.1 - 0.00083 17.9 0.1 0.0016 17.0 0.1 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) CoA_trans PF01144.18 EDO04983.1 - 1e-98 328.8 3.0 3.2e-57 193.1 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EDO04983.1 - 0.0026 17.4 0.2 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EDO04983.1 - 0.0084 15.8 0.1 1.6 8.4 0.0 2.6 3 0 0 3 3 3 2 Acetyl-CoA hydrolase/transferase N-terminal domain DUF2431 PF10354.4 EDO04985.1 - 2.3e-52 177.2 0.0 3e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ThiF PF00899.16 EDO04986.1 - 8.2e-17 61.3 0.0 1.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rad60-SLD PF11976.3 EDO04990.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DDE_1 PF03184.14 EDO04991.1 - 2.1e-11 43.3 0.1 1.8e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO04991.1 - 0.0023 17.7 0.1 0.0058 16.4 0.1 1.7 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain CoA_transf_3 PF02515.12 EDO04993.1 - 1e-30 106.3 0.0 2.2e-30 105.3 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III GKAP PF03359.8 EDO04994.1 - 4.9 6.6 8.9 7.7 6.0 6.2 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Acetyltransf_1 PF00583.19 EDO04995.1 - 4.1e-08 33.1 0.0 5.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO04995.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO04995.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO04995.1 - 9e-05 22.1 0.1 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EDO04995.1 - 0.00061 19.6 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDO04995.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WSC PF01822.14 EDO04996.1 - 1.2e-31 108.4 24.5 2.5e-19 68.9 4.9 4.6 4 1 1 5 5 5 2 WSC domain Acetyltransf_1 PF00583.19 EDO04998.1 - 6.1e-10 38.9 0.0 8.1e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDO04998.1 - 6.4e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3648 PF12364.3 EDO05003.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) Chal_sti_synt_C PF02797.10 EDO05004.1 - 0.12 12.3 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Redoxin PF08534.5 EDO05008.1 - 6.2e-27 93.9 0.0 8.7e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO05008.1 - 2.6e-06 27.1 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family PIF1 PF05970.9 EDO05009.1 - 6.5e-38 130.6 0.1 2.1e-22 79.6 0.0 2.9 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EDO05009.1 - 1.9e-13 50.4 0.0 2.2e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Cauli_VI PF01693.11 EDO05009.1 - 1.8e-12 47.0 0.1 3.4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_19 PF13245.1 EDO05009.1 - 1.5e-07 31.0 0.0 3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDO05009.1 - 5.8e-07 29.5 0.0 2.5e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EDO05009.1 - 0.0004 20.5 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO05009.1 - 0.00057 19.5 0.2 0.054 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EDO05009.1 - 0.0012 17.8 0.1 0.0064 15.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.9 EDO05009.1 - 0.0018 16.1 0.0 0.011 13.5 0.0 1.9 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.13 EDO05009.1 - 0.0021 17.6 0.0 0.57 9.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EDO05009.1 - 0.0022 16.9 0.3 0.0043 15.9 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 EDO05009.1 - 0.0024 17.2 0.1 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EDO05009.1 - 0.0029 17.1 1.2 0.058 12.8 0.2 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EDO05009.1 - 0.0033 16.6 0.1 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 EDO05009.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EDO05009.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EDO05009.1 - 0.015 14.8 0.1 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDO05009.1 - 0.028 14.1 0.2 4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 EDO05009.1 - 0.04 12.8 0.1 0.072 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_32 PF13654.1 EDO05009.1 - 0.04 12.5 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EDO05009.1 - 0.048 12.2 0.1 0.078 11.5 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EDO05009.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EDO05009.1 - 0.067 13.0 0.2 0.28 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDO05009.1 - 0.12 12.0 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 EDO05009.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDO05009.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EDO05009.1 - 0.18 10.9 0.1 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RRM_1 PF00076.17 EDO05010.1 - 1.7e-19 69.2 0.0 2.4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO05010.1 - 1.7e-13 50.3 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO05010.1 - 1.1e-10 41.1 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.6 EDO05011.1 - 2.3e-74 248.8 0.1 4.3e-74 248.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EDO05011.1 - 0.005 15.1 0.3 0.0093 14.2 0.2 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase adh_short_C2 PF13561.1 EDO05012.1 - 5.4e-32 111.4 0.7 6.4e-32 111.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO05012.1 - 8.8e-29 100.5 0.0 1.4e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO05012.1 - 2e-12 47.1 0.1 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GMC_oxred_N PF00732.14 EDO05013.1 - 1.4e-40 139.3 0.4 1.8e-19 70.0 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EDO05013.1 - 4.4e-23 82.1 0.0 6.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EDO05013.1 - 0.031 14.2 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO05013.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATP_transf PF09830.4 EDO05014.1 - 4.9e-19 67.8 0.0 8.9e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.1 EDO05015.1 - 0.00076 19.5 0.1 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO05015.1 - 0.012 15.6 0.2 0.029 14.4 0.2 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO05015.1 - 0.027 14.5 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ndufs5 PF10200.4 EDO05018.1 - 0.00014 21.7 0.1 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EDO05018.1 - 0.011 15.8 0.2 0.02 15.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Sec39 PF08314.6 EDO05019.1 - 2.3e-259 862.1 0.0 2.7e-259 861.9 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Transpep_BrtH PF14399.1 EDO05019.1 - 0.027 13.7 0.5 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Methyltransf_23 PF13489.1 EDO05020.1 - 3e-15 56.3 0.0 4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO05020.1 - 4.1e-11 43.4 0.0 6.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO05020.1 - 2.9e-10 40.4 0.0 4.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO05020.1 - 3.1e-08 33.3 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO05020.1 - 2.1e-07 31.3 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO05020.1 - 6.5e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO05020.1 - 6.7e-05 22.5 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EDO05020.1 - 0.00029 20.8 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO05020.1 - 0.00034 19.7 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EDO05020.1 - 0.0032 16.6 0.0 0.0059 15.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 EDO05020.1 - 0.0056 15.6 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EDO05020.1 - 0.016 14.3 0.0 0.039 13.0 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDO05020.1 - 0.021 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 EDO05020.1 - 0.096 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.10 EDO05020.1 - 0.13 11.3 0.1 0.22 10.6 0.0 1.4 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G ApbA_C PF08546.6 EDO05022.1 - 3.7e-31 107.7 0.0 5.4e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDO05022.1 - 1.4e-23 83.0 0.0 2.6e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EDO05022.1 - 0.089 12.5 0.0 0.64 9.7 0.0 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ABC_tran PF00005.22 EDO05023.1 - 3.8e-47 160.0 0.0 6.8e-23 81.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO05023.1 - 1.8e-20 74.0 0.1 0.0012 18.9 0.0 4.2 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EDO05023.1 - 2.5e-19 68.8 6.3 3e-19 68.6 3.3 2.0 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EDO05023.1 - 6e-11 41.9 0.2 0.006 15.8 0.1 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDO05023.1 - 1.1e-09 38.9 1.4 0.032 14.5 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EDO05023.1 - 4.7e-09 35.6 0.1 0.0012 18.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDO05023.1 - 7.4e-07 28.4 0.1 0.00097 18.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO05023.1 - 1.8e-05 24.8 0.0 0.17 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDO05023.1 - 3.2e-05 24.2 0.0 0.067 13.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO05023.1 - 4.6e-05 24.2 0.1 0.72 10.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EDO05023.1 - 7.7e-05 22.6 0.0 0.11 12.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 EDO05023.1 - 9.6e-05 22.0 0.1 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EDO05023.1 - 0.00015 21.7 1.3 0.27 11.1 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 EDO05023.1 - 0.00018 21.6 1.2 1.5 9.0 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.1 EDO05023.1 - 0.00024 21.1 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EDO05023.1 - 0.00027 21.3 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EDO05023.1 - 0.00034 19.8 0.0 0.12 11.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EDO05023.1 - 0.00067 19.8 0.1 0.77 9.9 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO05023.1 - 0.00097 18.8 0.1 1 9.0 0.2 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EDO05023.1 - 0.0011 18.4 0.5 0.41 10.0 0.2 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EDO05023.1 - 0.0011 18.3 0.2 0.18 11.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO05023.1 - 0.0015 18.4 0.0 0.094 12.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EDO05023.1 - 0.0021 17.8 0.1 1.9 8.0 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 EDO05023.1 - 0.0027 17.4 0.3 0.052 13.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDO05023.1 - 0.0068 16.2 0.0 2.5 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDO05023.1 - 0.0071 15.2 0.0 4.1 6.1 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.1 EDO05023.1 - 0.0075 16.1 0.4 0.81 9.6 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF2813 PF11398.3 EDO05023.1 - 0.013 14.6 0.3 3.6 6.5 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 EDO05023.1 - 0.019 13.8 0.2 3.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ArgK PF03308.11 EDO05023.1 - 0.042 12.6 0.4 10 4.8 0.0 2.7 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 EDO05023.1 - 0.056 13.2 0.2 8.9 6.1 0.0 3.2 3 1 1 4 4 3 0 Dynamin family DUF815 PF05673.8 EDO05023.1 - 0.066 12.1 0.3 4.7 6.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 EDO05023.1 - 0.073 11.6 0.5 19 3.6 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class FeoB_N PF02421.13 EDO05023.1 - 0.092 12.0 0.1 6.5 6.0 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B NTPase_1 PF03266.10 EDO05023.1 - 0.1 12.3 0.1 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EDO05023.1 - 0.1 12.0 1.0 7.8 5.9 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 EDO05023.1 - 0.16 11.0 0.5 19 4.3 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 EDO05024.1 - 7.1e-71 238.4 1.7 1.4e-70 237.4 1.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EDO05024.1 - 1.4e-50 170.9 17.9 1.4e-50 170.9 12.4 3.4 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EDO05024.1 - 2.3e-16 59.4 0.5 2.1e-15 56.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Git3 PF11710.3 EDO05026.1 - 1.2e-07 31.5 1.9 1.6e-07 31.0 1.3 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Tmemb_40 PF10160.4 EDO05026.1 - 0.01 15.0 0.3 0.014 14.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein Glyco_hydro_43 PF04616.9 EDO05030.1 - 1.7e-10 40.4 0.1 2.2e-09 36.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF917 PF06032.7 EDO05031.1 - 3.7e-87 292.1 0.0 7.5e-87 291.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EDO05031.1 - 1.3e-44 152.4 5.3 5.4e-42 143.8 3.7 2.3 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDO05031.1 - 7.3e-23 80.9 4.9 5e-12 45.6 0.0 3.9 4 0 0 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EDO05031.1 - 0.00013 20.4 0.2 0.0015 16.9 0.0 2.2 2 0 0 2 2 2 1 MutL protein StbA PF06406.6 EDO05031.1 - 0.0031 16.4 0.5 0.39 9.5 0.0 2.3 2 0 0 2 2 2 2 StbA protein ATG22 PF11700.3 EDO05032.1 - 3.9e-127 424.6 24.4 4.5e-127 424.4 16.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EDO05032.1 - 3.7e-13 48.9 32.3 2.6e-07 29.7 4.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 EDO05032.1 - 0.084 12.3 1.0 0.19 11.2 0.7 1.5 1 0 0 1 1 1 0 Short C-terminal domain Nro1 PF12753.2 EDO05033.1 - 0.07 12.0 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Fungal_trans_2 PF11951.3 EDO05034.1 - 2.7e-70 236.8 0.0 3.2e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EDO05034.1 - 0.001 18.0 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTR2 PF00854.16 EDO05037.1 - 1.2e-19 70.3 5.6 1.1e-18 67.2 1.8 2.8 2 1 0 2 2 2 1 POT family Adap_comp_sub PF00928.16 EDO05038.1 - 1.5e-72 243.8 0.0 2.1e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO05038.1 - 5.1e-05 23.0 0.2 9.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EDO05038.1 - 0.037 13.9 0.2 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) CoA_binding PF02629.14 EDO05039.1 - 9.4e-27 93.3 3.4 7.1e-26 90.5 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EDO05039.1 - 4.3e-24 84.8 0.2 7.6e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EDO05039.1 - 1e-08 34.9 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EDO05039.1 - 0.012 15.7 0.1 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain T4_deiodinase PF00837.12 EDO05039.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Radical_SAM PF04055.16 EDO05040.1 - 7.8e-16 58.6 0.0 3.4e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EDO05040.1 - 2.8e-12 46.4 0.0 7.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDO05040.1 - 0.0032 17.5 0.1 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ATP-synt_C PF00137.16 EDO05042.1 - 2.7e-15 56.0 12.5 2.7e-15 56.0 8.7 1.8 2 0 0 2 2 2 1 ATP synthase subunit C Abhydrolase_3 PF07859.8 EDO05042.1 - 0.09 12.3 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 EDO05046.1 - 9.4e-18 64.4 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO05046.1 - 8.4e-09 36.0 0.0 0.00022 21.7 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EDO05046.1 - 1.8e-08 34.7 0.0 1.1e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO05046.1 - 1.5e-07 31.7 0.0 3.9e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO05046.1 - 5.7e-06 25.9 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EDO05046.1 - 0.0021 18.4 0.0 0.095 13.0 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO05046.1 - 0.0029 17.6 0.0 0.22 11.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EDO05046.1 - 0.0031 16.9 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EDO05046.1 - 0.0041 16.2 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EDO05046.1 - 0.014 14.7 0.0 0.098 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.7 EDO05046.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EDO05046.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.5 2 0 0 2 2 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EDO05046.1 - 0.069 12.2 0.0 8.8 5.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDO05046.1 - 0.075 12.0 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase CHRD PF07452.7 EDO05047.1 - 0.00037 21.1 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 CHRD domain