# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Retrotrans_gag PF03732.17 EEB04996.2 - 0.025 14.8 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 EEB04997.1 - 7.9e-07 29.3 0.2 1.2e-06 28.6 0.2 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Helicase_C PF00271.31 EEB05000.2 - 3.6e-16 59.5 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB05000.2 - 1.2e-10 41.4 0.0 4.3e-09 36.4 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase OrsD PF12013.8 EEB05000.2 - 4.9e-08 33.4 21.7 3.7e-07 30.6 1.5 4.7 4 1 0 4 4 4 2 Orsellinic acid/F9775 biosynthesis cluster protein D TetR_N PF00440.23 EEB05000.2 - 5.5e-05 22.9 0.3 0.5 10.2 0.1 3.5 3 0 0 3 3 3 2 Bacterial regulatory proteins, tetR family Herpes_pp85 PF04637.12 EEB05000.2 - 0.0004 19.0 0.0 0.66 8.3 0.0 2.2 2 0 0 2 2 2 2 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ResIII PF04851.15 EEB05000.2 - 0.0034 17.4 0.0 0.0086 16.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2HE PF16278.5 EEB05000.2 - 1.3 9.5 9.6 39 4.8 0.1 4.8 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger YgbA_NO PF11756.8 EEB05000.2 - 2.1 8.7 13.4 4 7.8 2.3 3.2 2 1 0 3 3 3 0 Nitrous oxide-stimulated promoter zf_C2H2_13 PF18508.1 EEB05000.2 - 2.6 7.7 12.3 3.2 7.4 0.2 3.8 3 0 0 3 3 3 0 Zinc finger domain Helicase_C PF00271.31 EEB05003.2 - 9.8e-14 51.6 0.0 1.4e-12 48.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMV_1a PF12467.8 EEB05003.2 - 0.037 14.4 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Helicase_C_2 PF13307.6 EEB05003.2 - 0.072 13.3 1.3 0.11 12.7 0.3 1.8 2 1 0 2 2 2 0 Helicase C-terminal domain zf-met PF12874.7 EEB05004.1 - 0.0049 17.2 2.3 0.017 15.5 2.3 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EEB05004.1 - 0.0082 16.5 11.8 0.15 12.6 4.4 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type OrsD PF12013.8 EEB05004.1 - 0.0082 16.6 0.0 0.0082 16.6 0.0 2.3 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EEB05004.1 - 0.35 11.8 25.1 4.9 8.3 3.5 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger Actin_micro PF17003.5 EEB05004.1 - 0.39 9.9 4.3 5.7 6.0 0.6 2.1 2 0 0 2 2 2 0 Putative actin-like family zf-Di19 PF05605.12 EEB05004.1 - 2.7 8.4 15.0 0.72 10.2 0.3 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Asp_protease_2 PF13650.6 EEB05005.1 - 5.1e-09 36.7 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EEB05005.1 - 3.4e-08 33.9 0.0 6.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EEB05005.1 - 4e-05 23.5 0.7 8.2e-05 22.5 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 EEB05005.1 - 0.06 13.7 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 EEB05005.1 - 0.091 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_5 PF14787.6 EEB05005.1 - 1 9.1 5.1 0.62 9.8 2.2 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 EEB05010.2 - 1.1e-07 32.0 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein HMG_box PF00505.19 EEB05014.2 - 6.9e-19 68.0 1.5 7.9e-19 67.8 0.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEB05014.2 - 1e-06 29.2 0.4 2e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 HMG-box domain LEDGF PF11467.8 EEB05015.2 - 0.021 14.5 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Homeobox_KN PF05920.11 EEB05015.2 - 0.11 12.4 0.4 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Homeobox KN domain Chromo PF00385.24 EEB05017.1 - 0.00018 21.3 3.0 0.00028 20.7 3.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 EEB05019.2 - 5.7e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OrsD PF12013.8 EEB05019.2 - 7.6e-10 39.2 0.9 2.7e-09 37.5 0.9 2.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D ResIII PF04851.15 EEB05019.2 - 4.2e-06 26.9 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB05019.2 - 4.2e-06 27.1 0.0 2.3e-05 24.7 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 EEB05019.2 - 0.09 12.1 0.0 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain Pkinase PF00069.25 EEB05020.1 - 5.6e-46 157.0 0.0 6.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05020.1 - 6.4e-32 110.9 0.0 7.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05020.1 - 5.4e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB05020.1 - 0.00036 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB05020.1 - 0.05 12.4 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase zf-met PF12874.7 EEB05022.1 - 0.00085 19.6 0.3 0.00085 19.6 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEB05022.1 - 0.0052 17.0 0.2 0.016 15.5 0.2 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 EEB05022.1 - 0.018 15.5 0.8 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EEB05022.1 - 0.02 15.7 0.4 0.02 15.7 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger AKAP95 PF04988.12 EEB05022.1 - 0.075 13.3 3.3 5.6 7.2 2.2 2.6 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 EEB05022.1 - 0.085 13.4 0.3 0.085 13.4 0.3 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 EEB05022.1 - 0.11 12.1 1.6 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EEB05022.1 - 0.18 12.1 4.0 1.9 8.8 0.6 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 EEB05023.1 - 7.2e-06 26.4 7.3 0.0097 16.3 0.1 3.2 2 1 1 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 EEB05023.1 - 0.0041 17.4 4.4 0.16 12.3 2.5 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding P53_tetramer PF07710.11 EEB05023.1 - 0.048 13.0 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif zf-met PF12874.7 EEB05023.1 - 0.059 13.8 4.0 0.91 10.0 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DGC PF08859.11 EEB05023.1 - 0.071 13.2 0.3 0.16 12.1 0.2 1.7 2 0 0 2 2 2 0 DGC domain zf-C2H2_4 PF13894.6 EEB05023.1 - 0.1 13.5 1.4 0.1 13.5 1.4 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger WSK PF03832.13 EEB05023.1 - 0.21 11.3 0.8 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 WSK motif Actin_micro PF17003.5 EEB05023.1 - 2.5 7.2 5.8 5.9 6.0 0.6 2.1 2 0 0 2 2 2 0 Putative actin-like family DUF629 PF04780.12 EEB05023.1 - 8.7 4.7 11.5 2.7 6.4 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF629) OrsD PF12013.8 EEB05024.1 - 6.3e-05 23.4 3.7 0.018 15.5 0.1 3.1 3 0 0 3 3 3 2 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 EEB05024.1 - 0.059 12.5 1.7 0.25 10.5 1.7 1.9 1 1 0 1 1 1 0 Putative actin-like family zf_UBZ PF18439.1 EEB05024.1 - 0.1 12.2 1.3 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_12 PF18658.1 EEB05024.1 - 0.13 11.8 1.9 14 5.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 EEB05024.1 - 0.18 12.3 0.3 0.18 12.3 0.3 4.1 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB05024.1 - 0.77 10.8 13.0 0.6 11.1 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 EEB05024.1 - 1.8 8.7 4.7 5.6 7.1 0.3 2.6 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 EEB05024.1 - 3 7.7 7.1 14 5.6 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain AA_permease_2 PF13520.6 EEB05026.1 - 2e-54 185.0 53.3 2.5e-54 184.8 53.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB05026.1 - 2.1e-11 43.1 43.9 2.8e-11 42.7 43.9 1.2 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.13 EEB05028.1 - 2.4e-24 86.1 0.8 3.9e-24 85.4 0.8 1.3 1 0 0 1 1 1 1 RTA1 like protein AA_permease_2 PF13520.6 EEB05029.1 - 5.9e-54 183.5 51.5 7.3e-54 183.2 51.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB05029.1 - 3.1e-16 59.0 44.5 5.9e-16 58.1 44.5 1.3 1 1 0 1 1 1 1 Amino acid permease Transferase PF02458.15 EEB05030.1 - 1.7e-20 73.1 0.0 2.3e-16 59.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family DIM PF08194.12 EEB05030.1 - 0.11 12.7 2.0 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 DIM protein Transferase PF02458.15 EEB05031.1 - 1.2e-19 70.3 0.0 1.2e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Transferase family C_LFY_FLO PF17538.2 EEB05033.1 - 0.089 12.3 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Gp_dh_C PF02800.20 EEB05035.1 - 9.1e-72 239.8 0.1 1.3e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEB05035.1 - 4e-40 136.2 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEB05035.1 - 0.028 14.5 1.6 0.1 12.7 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EEB05035.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3576 PF12100.8 EEB05035.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) RhoGAP PF00620.27 EEB05036.1 - 1.9e-17 63.5 0.0 3.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Arm PF00514.23 EEB05037.1 - 2.2e-75 246.6 30.4 5.3e-10 39.0 0.0 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EEB05037.1 - 1e-16 61.1 9.6 0.0017 18.7 0.1 6.9 2 2 6 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 EEB05037.1 - 7e-16 58.4 14.8 0.0061 17.1 0.2 8.3 10 1 1 11 11 9 4 HEAT-like repeat KAP PF05804.12 EEB05037.1 - 1.3e-11 43.5 1.0 1.9e-11 42.9 1.0 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT PF02985.22 EEB05037.1 - 1.5e-10 40.4 19.5 0.15 12.4 0.4 9.1 10 0 0 10 10 10 4 HEAT repeat Arm_2 PF04826.13 EEB05037.1 - 1.7e-10 40.8 10.4 0.00013 21.6 0.9 3.3 1 1 1 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 EEB05037.1 - 8.6e-10 38.4 6.8 1.9e-06 27.4 1.8 3.9 1 1 2 3 3 3 3 V-ATPase subunit H Adaptin_N PF01602.20 EEB05037.1 - 6.3e-08 31.6 17.2 1.6e-05 23.7 0.8 2.8 1 1 2 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EEB05037.1 - 0.00011 22.3 6.1 0.15 12.1 0.3 4.6 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EEB05037.1 - 0.00038 20.4 8.7 0.61 10.0 0.2 3.9 2 1 1 4 4 4 2 Domain of unknown function (DUF3361) UNC45-central PF11701.8 EEB05037.1 - 0.0068 16.4 7.6 1.8 8.5 0.2 4.0 3 1 1 4 4 4 2 Myosin-binding striated muscle assembly central WAPL PF07814.13 EEB05037.1 - 0.012 14.4 0.4 0.012 14.4 0.4 2.5 2 1 1 3 3 3 0 Wings apart-like protein regulation of heterochromatin DUF5578 PF17741.1 EEB05037.1 - 0.015 14.7 11.5 4.4 6.7 2.0 4.5 1 1 1 4 4 4 0 Family of unknown function (DUF5578) DrsE PF02635.15 EEB05037.1 - 0.027 14.9 0.0 0.081 13.3 0.0 1.8 1 0 0 1 1 1 0 DsrE/DsrF-like family YqfD PF06898.11 EEB05037.1 - 0.035 12.9 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD HEAT_PBS PF03130.16 EEB05037.1 - 0.062 14.0 6.3 46 5.1 0.1 6.5 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 EEB05037.1 - 0.57 10.2 7.2 7.1 6.7 0.2 4.2 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain SH3_1 PF00018.28 EEB05038.2 - 1.6e-05 24.4 1.1 2.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEB05038.2 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SpvB PF03534.13 EEB05038.2 - 3.6 6.7 7.4 4.4 6.4 0.1 2.5 3 0 0 3 3 3 0 Salmonella virulence plasmid 65kDa B protein Dynamin_N PF00350.23 EEB05039.1 - 9.3e-16 58.3 0.6 8.5e-15 55.2 0.1 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EEB05039.1 - 1.4e-10 41.2 0.0 1e-09 38.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEB05039.1 - 3.2e-08 33.3 3.7 8.8e-07 28.6 3.8 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB05039.1 - 8.3e-05 22.5 0.6 0.85 9.5 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase cobW PF02492.19 EEB05039.1 - 0.00028 20.5 0.1 0.041 13.5 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EEB05039.1 - 0.0014 18.4 0.2 2 8.1 0.2 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 EEB05039.1 - 0.0018 17.4 0.2 0.0073 15.4 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EEB05039.1 - 0.0031 17.9 0.6 0.074 13.4 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EEB05039.1 - 0.0039 17.4 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EEB05039.1 - 0.0054 16.2 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 EEB05039.1 - 0.012 15.1 0.4 3.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 EEB05039.1 - 0.032 14.8 0.2 0.27 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EEB05039.1 - 0.056 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF489 PF04356.12 EEB05039.1 - 0.064 13.3 0.8 0.26 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) AAA_29 PF13555.6 EEB05039.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF948 PF06103.11 EEB05039.1 - 0.25 11.6 2.5 1.3 9.3 0.5 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Arrestin_C PF02752.22 EEB05040.1 - 2.2e-13 50.8 0.1 5.4e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEB05040.1 - 0.00051 20.1 0.1 0.0021 18.1 0.1 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Cullin_binding PF03556.15 EEB05041.1 - 7.6e-30 103.8 1.2 4.2e-29 101.4 0.2 2.1 2 0 0 2 2 2 1 Cullin binding RGS PF00615.19 EEB05041.1 - 0.54 10.5 4.0 0.28 11.4 0.7 2.1 2 1 0 2 2 2 0 Regulator of G protein signaling domain Ribosomal_L2_C PF03947.18 EEB05042.1 - 2e-41 141.1 3.8 2e-41 141.1 3.8 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEB05042.1 - 7.4e-15 54.7 0.1 2e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Allantoicase PF03561.15 EEB05043.1 - 2.2e-94 313.0 0.0 1.1e-46 158.3 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Asp_Glu_race PF01177.22 EEB05044.2 - 3.8e-09 36.7 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 EEB05044.2 - 0.041 13.5 0.6 0.056 13.1 0.6 1.2 1 0 0 1 1 1 0 Arylmalonate decarboxylase Fungal_trans PF04082.18 EEB05045.2 - 5.7e-21 74.7 0.1 9.5e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB05045.2 - 7e-05 22.9 10.9 0.00013 22.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EEB05046.1 - 6.2e-78 262.0 0.0 7.1e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 EEB05046.1 - 0.045 14.1 0.0 62 3.9 0.0 3.3 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family NAF PF03822.14 EEB05046.1 - 0.26 11.5 0.4 6.1 7.1 0.0 2.5 3 0 0 3 3 3 0 NAF domain 6PF2K PF01591.18 EEB05047.1 - 2.2e-46 158.0 3.9 3.1e-46 157.5 3.9 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.10 EEB05047.1 - 1.5e-06 27.8 0.4 2.6e-06 27.1 0.4 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EEB05047.1 - 1.7e-06 28.2 0.0 3.9e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain His_Phos_1 PF00300.22 EEB05047.1 - 2.8e-06 27.2 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CPT PF07931.12 EEB05047.1 - 0.062 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EEB05047.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FeS_assembly_P PF01883.19 EEB05048.1 - 5.3e-12 45.7 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Vps51 PF08700.11 EEB05049.1 - 2.4e-10 40.3 1.6 5.3e-10 39.3 0.2 2.4 2 0 0 2 2 2 1 Vps51/Vps67 V-SNARE PF05008.15 EEB05049.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Kinesin PF00225.23 EEB05050.1 - 5.1e-09 35.5 0.0 5.8e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEB05050.1 - 9.7e-08 32.1 0.2 2.9e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding T2SSE PF00437.20 EEB05050.1 - 0.036 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Orn_Arg_deC_N PF02784.16 EEB05051.1 - 2.6e-78 262.8 0.0 1.1e-77 260.8 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EEB05051.1 - 1.1e-19 70.5 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF5032 PF16435.5 EEB05051.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Adenylsucc_synt PF00709.21 EEB05052.1 - 4.7e-180 599.0 0.0 5.4e-180 598.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase zf-H2C2_2 PF13465.6 EEB05053.1 - 6.6e-09 35.8 6.8 4.4e-06 26.9 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EEB05053.1 - 4.5e-07 30.0 14.2 2.6e-06 27.6 0.2 3.9 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EEB05053.1 - 7.9e-05 23.2 14.4 0.056 14.1 0.2 4.1 3 1 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EEB05053.1 - 0.00023 21.7 6.6 0.00074 20.1 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEB05053.1 - 0.00025 20.9 0.4 0.0037 17.2 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EEB05053.1 - 0.051 13.4 0.4 0.53 10.1 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 EEB05053.1 - 0.082 13.3 0.1 6.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EEB05053.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 EEB05053.1 - 0.16 12.1 0.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger Sec2p PF06428.11 EEB05053.1 - 2.2 8.3 7.0 13 5.8 0.8 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PemK_toxin PF02452.17 EEB05054.1 - 0.033 14.6 0.1 0.04 14.3 0.1 1.1 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Porin_3 PF01459.22 EEB05056.1 - 6e-65 219.4 0.7 6.7e-65 219.2 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2408 PF10303.9 EEB05057.1 - 1e-53 181.5 10.2 3.4e-33 115.1 0.1 5.1 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) PQ-loop PF04193.14 EEB05059.1 - 5.9e-35 118.9 11.8 1.3e-19 69.7 2.1 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF2157 PF09925.9 EEB05059.1 - 0.0019 18.0 6.9 0.31 10.8 0.1 3.3 3 1 1 4 4 4 2 Predicted membrane protein (DUF2157) ER_lumen_recept PF00810.18 EEB05059.1 - 0.024 15.5 4.5 4.4 8.1 0.0 2.5 2 1 0 2 2 2 0 ER lumen protein retaining receptor UBX PF00789.20 EEB05060.1 - 8.8e-06 25.8 0.0 9.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 EEB05060.1 - 0.0041 17.6 0.3 0.9 10.1 0.5 2.4 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 RA PF00788.23 EEB05060.1 - 0.019 15.6 0.2 0.12 13.0 0.0 2.4 2 1 0 2 2 2 0 Ras association (RalGDS/AF-6) domain zf-C2H2 PF00096.26 EEB05060.1 - 0.027 14.9 0.2 0.048 14.1 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type GREB1 PF15782.5 EEB05060.1 - 0.66 7.0 10.4 0.74 6.9 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 EEB05060.1 - 1.1 8.9 19.9 1.3 8.6 19.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SapB_1 PF05184.15 EEB05060.1 - 6.1 7.0 6.4 49 4.1 0.3 3.7 4 0 0 4 4 4 0 Saposin-like type B, region 1 Motile_Sperm PF00635.26 EEB05061.2 - 0.013 15.3 0.0 0.043 13.7 0.0 1.9 1 1 0 1 1 1 0 MSP (Major sperm protein) domain Cut8 PF08559.10 EEB05062.1 - 6.2e-50 170.0 2.0 7.5e-50 169.8 2.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Sugar_tr PF00083.24 EEB05063.1 - 5.4e-124 414.5 25.3 6.4e-124 414.2 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB05063.1 - 1.3e-21 77.0 27.7 1.2e-17 63.9 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Holin_BlyA PF05102.12 EEB05063.1 - 0.024 14.6 0.4 0.06 13.3 0.4 1.6 1 0 0 1 1 1 0 holin, BlyA family Pox_A14 PF05767.12 EEB05063.1 - 0.16 12.1 2.5 0.92 9.7 0.1 3.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Phage_holin_2_4 PF16082.5 EEB05063.1 - 0.51 10.1 2.2 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TPR_14 PF13428.6 EEB05064.1 - 8.2e-11 41.8 3.8 0.61 11.0 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat NRDE-2 PF08424.10 EEB05064.1 - 0.0003 20.0 2.5 0.008 15.3 0.0 3.7 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference Suf PF05843.14 EEB05064.1 - 0.00043 20.4 7.5 0.00078 19.5 1.1 2.6 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EEB05064.1 - 0.067 13.8 0.2 14 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05064.1 - 0.07 13.5 0.1 1.1e+02 3.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat BfiI_DBD PF18243.1 EEB05064.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain APG5 PF04106.12 EEB05065.1 - 8.2e-51 172.8 0.2 9.8e-51 172.5 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 IGR PF09597.10 EEB05066.1 - 2.6e-21 75.5 0.4 4e-21 74.9 0.4 1.3 1 0 0 1 1 1 1 IGR protein motif MFS_1 PF07690.16 EEB05067.1 - 9.5e-38 130.0 20.1 3.7e-37 128.1 20.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 EEB05067.1 - 0.034 14.5 8.4 1.3 9.4 1.0 3.3 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V OSTbeta PF15048.6 EEB05067.1 - 0.1 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2678 PF10856.8 EEB05067.1 - 0.2 11.6 2.3 0.74 9.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF1003 PF06210.11 EEB05067.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) DUF3792 PF12670.7 EEB05067.1 - 0.58 10.3 12.0 0.043 14.0 2.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Syja_N PF02383.18 EEB05068.1 - 6.8e-75 252.3 0.1 1.1e-74 251.7 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EEB05068.1 - 2.2e-12 47.0 0.0 3.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec61_beta PF03911.16 EEB05069.1 - 6.4e-17 61.3 0.8 8.4e-17 60.9 0.8 1.2 1 0 0 1 1 1 1 Sec61beta family DUF2474 PF10617.9 EEB05069.1 - 0.14 12.1 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) ATP_bind_1 PF03029.17 EEB05070.1 - 2.2e-80 269.9 0.0 2.9e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EEB05070.1 - 0.00028 20.0 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 EEB05070.1 - 0.001 18.9 0.0 0.0054 16.5 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EEB05070.1 - 0.0065 16.6 0.1 0.018 15.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EEB05070.1 - 0.061 13.4 0.0 0.064 13.3 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EEB05070.1 - 0.063 13.7 1.1 0.53 10.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEB05070.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EEB05070.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.15 EEB05070.1 - 0.16 11.9 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 NTPase HSCB_C PF07743.13 EEB05071.1 - 1.1e-21 77.1 3.1 1.1e-21 77.1 3.1 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EEB05071.1 - 2.4e-06 27.6 3.9 2.8e-06 27.4 0.2 2.6 3 0 0 3 3 3 1 DnaJ domain DUF1640 PF07798.11 EEB05071.1 - 0.0084 16.2 0.3 0.012 15.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DNA_ligase_A_N PF04675.14 EEB05071.1 - 0.11 12.8 0.5 0.15 12.4 0.5 1.2 1 0 0 1 1 1 0 DNA ligase N terminus zf-C2H2 PF00096.26 EEB05072.2 - 1.5e-19 69.2 72.0 0.0045 17.4 1.9 9.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB05072.2 - 2.9e-15 55.6 70.3 0.011 16.5 0.2 10.1 10 1 1 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEB05072.2 - 4.3e-10 39.6 65.5 9.2e-05 22.7 0.5 10.5 10 1 0 10 10 10 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 EEB05072.2 - 1.1e-07 32.1 32.2 1.6e-05 25.1 8.0 5.1 2 1 4 6 6 6 4 C2H2-type zinc ribbon FOXP-CC PF16159.5 EEB05072.2 - 0.0017 19.0 31.6 0.036 14.7 0.8 7.3 3 1 5 8 8 8 2 FOXP coiled-coil domain YdjO PF14169.6 EEB05072.2 - 0.023 14.4 15.8 1.6 8.5 0.2 6.0 5 1 1 6 6 6 0 Cold-inducible protein YdjO zf-C2H2_aberr PF17017.5 EEB05072.2 - 0.16 12.1 34.0 0.16 12.1 2.9 6.4 3 1 4 8 8 8 0 Aberrant zinc-finger zf-C2H2_12 PF18658.1 EEB05072.2 - 1.3 8.7 17.9 5.1 6.8 0.1 5.1 3 1 2 5 5 5 0 Zinc-finger C2H2-type zf_ZIC PF18366.1 EEB05072.2 - 2.9 8.0 17.9 8 6.7 0.4 5.7 5 0 0 5 5 5 0 Zic proteins zinc finger domain GWT1 PF06423.12 EEB05073.1 - 3.9e-33 114.7 0.6 3.9e-33 114.7 0.6 3.1 3 1 1 4 4 4 1 GWT1 DUF1206 PF06724.11 EEB05073.1 - 5.4 7.2 7.9 2.1 8.5 0.1 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1206) Ribosomal_S17_N PF16205.5 EEB05074.1 - 1.3e-30 105.6 0.4 2.2e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EEB05074.1 - 5.4e-28 96.9 1.2 6.7e-28 96.6 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Rib_5-P_isom_A PF06026.14 EEB05075.1 - 2.1e-58 196.8 0.0 2.8e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.32 EEB05076.1 - 3.7e-22 78.2 6.0 1.7e-05 25.4 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05076.1 - 9.5e-16 57.9 1.1 4.2e-05 23.8 0.2 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB05076.1 - 0.00013 21.9 0.1 0.0041 17.0 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 EEB05076.1 - 0.0054 15.4 0.2 0.04 12.5 0.0 2.2 3 0 0 3 3 3 1 beta-propeller of ELYS nucleoporin Sec23_trunk PF04811.15 EEB05077.1 - 7e-73 245.2 0.0 1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEB05077.1 - 3.3e-19 68.6 0.4 8.8e-19 67.2 0.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEB05077.1 - 6.2e-18 65.3 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEB05077.1 - 2e-12 47.0 6.0 3.4e-12 46.2 6.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEB05077.1 - 5.6e-08 32.6 0.0 1.6e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Myb_DNA-binding PF00249.31 EEB05078.1 - 7.2e-22 77.3 3.4 5.3e-10 39.3 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB05078.1 - 1e-15 57.7 9.9 3.2e-07 30.5 0.2 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEB05078.1 - 0.024 14.8 3.3 4.5 7.5 0.0 3.3 2 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Cas3_C PF18395.1 EEB05078.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Cas3 C-terminal domain Myb_DNA-bind_4 PF13837.6 EEB05078.1 - 1 9.8 6.9 0.18 12.2 0.5 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Hydrolase_3 PF08282.12 EEB05079.1 - 1.1e-49 169.4 0.0 1.3e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EEB05079.1 - 1.4e-11 44.4 0.0 5.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EEB05079.1 - 1.4e-06 28.8 0.0 0.0081 16.5 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEB05079.1 - 0.00037 20.9 0.0 2.3 8.6 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEB05079.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EEB05079.1 - 0.0026 16.9 0.0 0.03 13.5 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase HAD_2 PF13419.6 EEB05079.1 - 0.045 13.8 0.0 6.2 6.9 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Transferase PF02458.15 EEB05080.1 - 2.2e-19 69.5 0.0 4.8e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family MFAP1 PF06991.11 EEB05081.1 - 1.4e-47 162.4 33.6 1.4e-47 162.4 33.6 2.8 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DUF1713 PF08213.11 EEB05082.1 - 2e-13 50.0 21.6 2e-13 50.0 21.6 1.6 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EEB05082.1 - 7.1e-07 30.0 0.0 9.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet20 PTPA PF03095.15 EEB05083.1 - 1.4e-117 392.4 0.0 1.7e-117 392.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Band_7 PF01145.25 EEB05084.1 - 5.6e-25 88.4 5.9 6.3e-25 88.2 4.5 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF1670 PF07900.11 EEB05084.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1670) Band_7_1 PF13421.6 EEB05084.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family UcrQ PF02939.16 EEB05085.1 - 1.8e-31 107.9 0.5 2e-31 107.7 0.5 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EEB05085.1 - 0.0013 19.1 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 RNase_T PF00929.24 EEB05086.1 - 1e-06 29.4 0.0 2.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 EEB05086.1 - 0.00026 21.3 0.9 0.00061 20.1 0.9 1.6 1 0 0 1 1 1 1 ElonginA binding-protein 1 FAP PF07174.11 EEB05086.1 - 1.1 8.6 9.2 1.7 8.1 9.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DSPn PF14671.6 EEB05087.1 - 9.3e-48 162.3 0.1 1.4e-46 158.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EEB05087.1 - 3e-19 69.1 0.0 3.1e-18 65.9 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB05087.1 - 3.4e-05 23.5 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEB05087.1 - 0.0011 19.2 0.1 0.0041 17.3 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 EEB05087.1 - 0.021 14.5 0.1 0.052 13.2 0.0 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) NYD-SP28 PF14772.6 EEB05087.1 - 0.08 13.0 3.8 0.16 12.0 3.8 1.4 1 0 0 1 1 1 0 Sperm tail Ribosomal_L7Ae PF01248.26 EEB05088.1 - 4.6e-27 93.6 1.1 6.2e-27 93.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APS_kinase PF01583.20 EEB05089.1 - 5.2e-74 247.4 0.0 6.3e-74 247.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EEB05089.1 - 8.5e-08 32.5 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEB05089.1 - 3.5e-05 24.4 0.0 6.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEB05089.1 - 0.00033 20.2 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 EEB05089.1 - 0.0074 16.1 0.2 0.2 11.5 0.2 2.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EEB05089.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EEB05089.1 - 0.029 14.8 0.0 0.029 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EEB05089.1 - 0.038 13.3 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF423 PF04241.15 EEB05090.1 - 2.4e-22 78.9 1.4 3.6e-22 78.4 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) MRP-L46 PF11788.8 EEB05091.1 - 6.7e-16 59.1 0.4 2.1e-15 57.5 0.1 1.9 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 SCA7 PF08313.12 EEB05092.1 - 1.8e-30 104.6 0.3 5.3e-30 103.1 0.3 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 EEB05092.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF2043 PF09740.9 EEB05092.1 - 0.053 14.2 0.6 0.15 12.8 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2043) Macoilin PF09726.9 EEB05092.1 - 0.99 7.9 11.4 1.2 7.6 11.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4670 PF15709.5 EEB05092.1 - 4 6.6 12.0 1.7 7.9 6.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4670) PseudoU_synth_1 PF01416.20 EEB05093.1 - 6.5e-11 42.7 0.0 3.2e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase EcoEI_R_C PF08463.10 EEB05093.1 - 0.068 13.3 0.1 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 EcoEI R protein C-terminal WD40 PF00400.32 EEB05096.1 - 9.8e-23 80.0 25.9 1.8e-05 25.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 EEB05096.1 - 7.8e-05 21.5 0.3 0.033 12.8 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEB05096.1 - 0.0086 16.4 0.3 0.75 10.1 0.1 3.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EEB05096.1 - 0.05 12.5 4.0 0.63 8.9 0.8 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RabGAP-TBC PF00566.18 EEB05097.2 - 4.2e-13 49.4 2.3 9.2e-13 48.3 2.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.6 EEB05097.2 - 6e-06 26.3 4.0 6e-06 26.3 4.0 3.7 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 EEB05097.2 - 0.00014 22.0 16.4 0.00014 22.0 16.4 3.1 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 EEB05097.2 - 0.00039 18.1 10.9 0.00056 17.6 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4472 PF14739.6 EEB05097.2 - 0.0026 18.5 19.7 0.028 15.1 9.4 2.7 2 1 1 3 3 2 2 Domain of unknown function (DUF4472) GAS PF13851.6 EEB05097.2 - 0.0045 16.4 19.4 0.18 11.1 11.7 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Filament PF00038.21 EEB05097.2 - 0.0059 16.2 18.1 0.15 11.6 18.1 2.4 1 1 0 1 1 1 1 Intermediate filament protein FAM76 PF16046.5 EEB05097.2 - 0.0069 15.8 6.9 0.017 14.5 6.9 1.6 1 0 0 1 1 1 1 FAM76 protein MatP PF06303.12 EEB05097.2 - 0.0086 16.6 1.1 1.7 9.3 0.0 3.1 3 0 0 3 3 2 1 MatP N-terminal domain CENP-F_leu_zip PF10473.9 EEB05097.2 - 0.011 15.8 10.0 0.011 15.8 10.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 EEB05097.2 - 0.015 15.5 17.1 0.82 9.9 3.4 5.1 4 1 0 4 4 4 0 Homeobox associated leucine zipper SHE3 PF17078.5 EEB05097.2 - 0.031 14.0 13.4 0.074 12.8 13.4 1.7 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Mod_r PF07200.13 EEB05097.2 - 0.047 13.8 20.0 0.072 13.2 5.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HOOK PF05622.12 EEB05097.2 - 0.059 11.5 15.4 0.11 10.6 15.4 1.3 1 0 0 1 1 1 0 HOOK protein MapZ_EC1 PF18041.1 EEB05097.2 - 0.059 13.6 11.8 0.29 11.4 4.0 2.7 2 0 0 2 2 2 0 MapZ extracellular domain 1 KASH_CCD PF14662.6 EEB05097.2 - 0.078 12.8 19.7 0.86 9.4 8.5 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 EEB05097.2 - 0.092 12.8 10.1 3.7 7.7 2.2 3.4 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF812 PF05667.11 EEB05097.2 - 0.12 11.2 16.8 0.21 10.4 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tau95 PF09734.9 EEB05097.2 - 0.23 12.3 4.3 0.18 12.6 2.2 2.0 2 1 0 2 2 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Spc7 PF08317.11 EEB05097.2 - 0.23 10.3 20.1 1.4 7.8 20.2 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 EEB05097.2 - 0.23 11.4 17.5 1 9.4 4.0 4.0 2 2 1 3 3 3 0 FlxA-like protein DUF4407 PF14362.6 EEB05097.2 - 0.25 10.7 15.1 1.2 8.4 15.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EEB05097.2 - 0.35 11.3 24.6 0.04 14.4 3.9 3.7 2 1 1 3 3 2 0 Cell division protein ZapB HMMR_C PF15908.5 EEB05097.2 - 0.41 10.9 11.7 1 9.6 11.7 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Fez1 PF06818.15 EEB05097.2 - 0.46 10.9 19.6 0.49 10.8 17.6 2.0 2 1 0 2 2 1 0 Fez1 ABC_tran_CTD PF16326.5 EEB05097.2 - 0.5 10.7 27.4 0.43 10.9 5.0 4.3 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF948 PF06103.11 EEB05097.2 - 0.58 10.5 6.0 11 6.3 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4600 PF15372.6 EEB05097.2 - 0.7 10.3 16.3 0.59 10.6 7.5 3.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4600) EzrA PF06160.12 EEB05097.2 - 0.73 7.9 18.4 2 6.5 18.3 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 EEB05097.2 - 1.1 9.4 25.6 0.32 11.2 11.3 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4795 PF16043.5 EEB05097.2 - 1.2 8.7 17.0 1.2 8.7 14.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3450 PF11932.8 EEB05097.2 - 1.7 7.9 18.6 2 7.7 8.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 EEB05097.2 - 1.8 7.6 14.5 6.5 5.7 14.4 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 EEB05097.2 - 1.8 9.0 7.3 5.3 7.5 0.3 3.7 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF4201 PF13870.6 EEB05097.2 - 1.9 8.2 19.2 1.1e+02 2.5 19.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 EEB05097.2 - 2.4 8.3 14.9 5.4 7.2 4.6 3.0 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 EEB05097.2 - 2.7 8.0 19.4 5.3e+02 0.5 19.4 2.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 EEB05097.2 - 2.8 8.4 20.5 0.2 12.1 9.5 2.7 2 1 1 3 3 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 EEB05097.2 - 3.4 8.2 32.0 0.088 13.3 18.4 2.9 2 1 1 3 3 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 EEB05097.2 - 3.4 7.7 8.6 3.3 7.7 3.3 2.4 1 1 0 2 2 2 0 Laminin Domain II DivIC PF04977.15 EEB05097.2 - 4.2 7.2 19.1 5.8 6.8 0.8 4.3 2 1 1 4 4 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 EEB05097.2 - 4.9 6.6 7.2 9.5 5.7 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.21 EEB05097.2 - 5.5 7.2 16.5 1.7 8.8 1.9 4.6 2 1 2 4 4 4 0 bZIP transcription factor Uso1_p115_C PF04871.13 EEB05097.2 - 5.9 7.3 25.9 5.4 7.4 15.2 2.7 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 EEB05097.2 - 9.9 6.2 15.0 11 6.1 0.6 3.0 2 1 0 3 3 2 0 Protein of unknown function (DUF1664) Nic96 PF04097.14 EEB05098.1 - 8.8e-169 562.9 3.2 8.8e-169 562.9 3.2 1.4 2 0 0 2 2 2 1 Nup93/Nic96 YlqD PF11068.8 EEB05098.1 - 0.057 13.8 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 YlqD protein UPF0254 PF06787.11 EEB05098.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Bud13 PF09736.9 EEB05099.1 - 7.8e-44 149.6 4.9 7.8e-44 149.6 4.9 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.12 EEB05100.2 - 3.2e-24 85.4 28.4 1.2e-12 47.3 22.5 2.1 2 0 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EEB05100.2 - 0.65 8.2 13.6 0.61 8.3 10.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Alpha-amylase PF00128.24 EEB05101.1 - 1.4e-50 172.7 1.7 2.1e-50 172.2 1.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EEB05101.1 - 1.5e-08 34.8 0.6 5e-08 33.1 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) HepII_C PF18675.1 EEB05101.1 - 0.02 15.0 0.3 0.14 12.3 0.0 2.5 2 1 0 2 2 2 0 Heparinase II C-terminal domain Aminotran_1_2 PF00155.21 EEB05102.1 - 4e-66 223.7 0.0 4.6e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEB05102.1 - 3.6e-06 25.8 0.0 5.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EEB05102.1 - 2.3e-05 23.9 0.1 3.9e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EEB05102.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V FA_desaturase PF00487.24 EEB05103.1 - 1.7e-22 80.5 20.5 4.7e-22 79.0 20.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EEB05103.1 - 6.3e-06 26.4 0.0 1.8e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) DUF5592 PF17332.2 EEB05103.1 - 0.01 16.3 2.0 2.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Cyclin_N PF00134.23 EEB05104.2 - 1.9e-11 43.8 0.5 3.2e-11 43.1 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 EEB05105.1 - 1.4e-22 80.2 9.7 1.7e-22 79.9 9.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FPN1 PF06963.12 EEB05105.1 - 2.1e-05 23.3 0.0 3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Sugar_tr PF00083.24 EEB05105.1 - 7e-05 21.9 3.6 0.00021 20.3 3.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EEB05105.1 - 0.00031 19.2 0.2 0.00036 19.0 0.2 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 EEB05105.1 - 0.0045 15.5 0.2 0.0071 14.8 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OAD_gamma PF04277.13 EEB05105.1 - 0.012 16.2 0.1 0.035 14.7 0.1 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4231 PF14015.6 EEB05105.1 - 0.016 15.7 0.7 1.1 9.8 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2140 PF09911.9 EEB05105.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) TMEM208_SND2 PF05620.11 EEB05105.1 - 0.093 12.5 1.4 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ABC2_membrane_3 PF12698.7 EEB05105.1 - 8.1 5.4 12.4 2.9 6.9 0.1 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Wzy_C PF04932.15 EEB05105.1 - 9.3 5.9 12.3 1e+02 2.5 12.3 2.4 1 1 0 1 1 1 0 O-Antigen ligase NMT PF01233.19 EEB05107.1 - 1.4e-76 255.8 0.2 3.6e-75 251.2 0.1 2.2 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EEB05107.1 - 1.7e-50 171.4 0.0 2.7e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 EEB05107.1 - 0.00086 19.4 0.0 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB05107.1 - 0.049 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family tRNA-synt_His PF13393.6 EEB05108.1 - 8.3e-42 143.5 0.0 4.8e-36 124.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase WHEP-TRS PF00458.20 EEB05108.1 - 4.8e-17 61.9 2.7 1.6e-16 60.1 2.7 2.0 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.20 EEB05108.1 - 3e-12 46.5 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EEB05108.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EEB05108.1 - 0.024 13.7 0.0 0.13 11.3 0.0 1.8 1 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EEB05108.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Adaptin_N PF01602.20 EEB05109.1 - 1.5e-93 314.2 6.9 6.8e-73 246.0 1.0 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EEB05109.1 - 1.3e-20 74.1 5.3 4.1e-18 65.9 0.2 3.9 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEB05109.1 - 1.4e-06 28.6 0.7 6.8 7.2 0.0 5.2 2 2 3 5 5 5 3 HEAT repeats TIP120 PF08623.10 EEB05109.1 - 0.0035 17.1 0.3 1.4 8.7 0.1 3.6 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EEB05109.1 - 0.05 13.9 1.1 2.2 8.8 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Mit_ribos_Mrp51 PF11709.8 EEB05110.1 - 4.2e-17 62.8 0.1 1.4e-16 61.1 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit FTHFS PF01268.19 EEB05111.1 - 1.6e-254 845.3 0.0 1.9e-254 845.0 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EEB05111.1 - 6.8e-67 223.8 1.2 1.2e-66 223.0 0.3 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EEB05111.1 - 7.4e-38 129.4 0.0 1.4e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ApoO PF09769.9 EEB05111.1 - 0.17 11.9 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein O Ribonuc_L-PSP PF01042.21 EEB05112.1 - 4.8e-41 139.6 0.1 5.9e-41 139.3 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Adaptin_N PF01602.20 EEB05113.2 - 3.1e-97 326.3 15.5 3.9e-97 326.0 15.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEB05113.2 - 1.1e-12 48.4 3.7 8.6e-11 42.1 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEB05113.2 - 6.1e-08 32.3 1.2 0.92 9.9 0.1 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EEB05113.2 - 2.6e-05 24.5 0.0 0.037 14.4 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats RTP1_C1 PF10363.9 EEB05113.2 - 0.00034 20.8 0.6 0.27 11.4 0.1 4.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EEB05113.2 - 0.00036 19.8 0.8 0.26 10.4 0.1 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 EEB05113.2 - 0.0045 17.0 2.1 36 4.6 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Asp PF00026.23 EEB05114.1 - 3.2e-55 187.8 7.9 6e-55 186.9 7.9 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEB05114.1 - 1.1e-11 45.2 0.2 5e-11 43.2 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EEB05114.1 - 0.0014 18.4 0.2 0.0055 16.5 0.1 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal But2 PF09792.9 EEB05115.1 - 4.6e-27 95.2 0.1 9.8e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain SNF2_N PF00176.23 EEB05116.2 - 5.7e-58 196.3 0.3 1.1e-57 195.4 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EEB05116.2 - 1.5e-07 31.7 14.3 1.5e-07 31.7 14.3 3.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEB05116.2 - 6e-07 29.2 12.0 6e-07 29.2 12.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB05116.2 - 1e-06 28.5 12.4 1e-06 28.5 12.4 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 EEB05116.2 - 5e-06 26.8 0.1 1.6e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EEB05116.2 - 0.00028 20.7 13.6 0.00028 20.7 13.6 2.8 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEB05116.2 - 0.00035 20.4 10.9 0.00098 18.9 10.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEB05116.2 - 0.0032 17.4 13.1 0.0032 17.4 13.1 2.6 2 0 0 2 2 1 1 zinc-RING finger domain ResIII PF04851.15 EEB05116.2 - 0.0046 17.0 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 EEB05116.2 - 0.25 11.4 8.7 0.27 11.3 6.2 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 EEB05116.2 - 1.4 8.9 6.2 4.4 7.2 6.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EEB05116.2 - 1.7 9.0 23.1 0.03 14.6 13.6 3.0 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEB05116.2 - 2.9 8.0 8.0 13 5.9 5.4 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EEB05116.2 - 3.5 7.9 14.5 1.9 8.7 11.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Telomere_reg-2 PF10193.9 EEB05117.2 - 8.2e-29 100.2 0.1 2.5e-28 98.7 0.1 1.9 1 0 0 1 1 1 1 Telomere length regulation protein DLIC PF05783.11 EEB05118.2 - 0.0019 17.1 0.6 0.55 9.0 0.1 2.9 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Pap_E4 PF02711.14 EEB05118.2 - 0.018 16.0 0.2 0.049 14.6 0.2 1.7 1 0 0 1 1 1 0 E4 protein PI3Ka PF00613.20 EEB05119.1 - 1.4e-60 203.8 3.3 2.4e-60 203.1 3.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EEB05119.1 - 2.5e-47 161.8 0.2 1.9e-30 106.5 0.0 2.9 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EEB05119.1 - 4.3e-20 72.1 0.0 7.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 WD40 PF00400.32 EEB05120.1 - 3.5e-05 24.5 0.0 0.0075 17.1 0.0 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05120.1 - 4.8e-05 23.6 0.0 0.65 10.3 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Spermine_synt_N PF17284.2 EEB05120.1 - 0.013 15.4 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain TFIIE_alpha PF02002.17 EEB05121.1 - 1.5e-18 66.5 0.6 8.5e-18 64.1 0.2 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EEB05121.1 - 0.0065 16.0 3.1 0.0077 15.7 1.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf_UBZ PF18439.1 EEB05121.1 - 0.051 13.2 0.6 1.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 EEB05121.1 - 0.086 12.9 1.0 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EEB05121.1 - 0.1 13.5 0.6 2.1 9.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ADK_lid PF05191.14 EEB05121.1 - 0.27 11.2 1.5 0.78 9.8 1.5 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid CRIM PF16978.5 EEB05122.2 - 4.7e-47 159.7 1.1 1.3e-46 158.2 0.1 2.3 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EEB05122.2 - 2.9e-32 111.2 2.1 3.8e-31 107.6 2.0 2.7 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EEB05122.2 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain PH PF00169.29 EEB05123.2 - 2.8e-07 31.0 0.0 7.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PH domain TFIIS_C PF01096.18 EEB05124.1 - 8.8e-13 47.9 6.7 8.8e-13 47.9 6.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEB05124.1 - 3.5e-11 42.8 2.9 3.5e-11 42.8 2.9 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF3716 PF12511.8 EEB05124.1 - 0.012 15.6 9.0 0.65 10.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Nudix_N_2 PF14803.6 EEB05124.1 - 2.4 8.2 9.9 2.7 8.0 1.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal Cytochrom_NNT PF03264.14 EEB05124.1 - 2.9 7.6 10.8 0.18 11.5 2.8 2.3 1 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region zf-RRN7 PF11781.8 EEB05124.1 - 5.9 6.7 16.5 7.3 6.4 0.7 4.1 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 P5CR_dimer PF14748.6 EEB05125.2 - 9.2e-22 77.3 0.7 2.3e-21 76.0 0.7 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EEB05125.2 - 2.8e-09 37.4 0.1 1.7e-08 34.9 0.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent zf-H2C2_2 PF13465.6 EEB05127.1 - 1.7e-05 25.0 2.2 1.7e-05 25.0 2.2 3.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EEB05127.1 - 0.00058 20.2 19.2 0.0051 17.2 3.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB05127.1 - 0.0081 16.9 16.2 0.32 12.0 2.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEB05127.1 - 0.022 14.5 2.3 0.022 14.5 2.3 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EEB05127.1 - 0.32 11.5 8.4 4.7 7.8 3.1 2.9 2 1 1 3 3 3 0 Zinc-finger of C2H2 type DUF629 PF04780.12 EEB05127.1 - 2.1 6.8 4.5 2.6 6.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Peptidase_C97 PF05903.14 EEB05128.1 - 2.4e-34 118.4 0.0 3.1e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EEB05128.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Ecm29 PF13001.7 EEB05129.1 - 2e-63 214.8 9.7 3.7e-37 128.2 0.1 3.7 2 1 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 EEB05129.1 - 0.014 16.0 0.2 0.47 11.1 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region PriA_3primeBD PF17764.1 EEB05129.1 - 0.17 11.8 0.0 0.68 9.9 0.0 2.0 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) HEAT PF02985.22 EEB05129.1 - 0.38 11.1 3.7 13 6.3 0.0 5.7 7 0 0 7 7 7 0 HEAT repeat Ilm1 PF10311.9 EEB05130.1 - 1.4e-17 63.8 2.7 4.3e-10 39.5 0.5 2.1 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 Proteasome PF00227.26 EEB05131.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_20 PF00982.21 EEB05132.1 - 3e-144 481.3 0.4 4.2e-144 480.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEB05132.1 - 9.8e-36 123.0 0.0 1.5e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Thioredoxin PF00085.20 EEB05133.1 - 1.3e-06 28.3 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EEB05133.1 - 1.1e-05 25.0 0.0 8.6e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Metallophos PF00149.28 EEB05134.1 - 1.7e-14 54.8 0.8 2.5e-14 54.3 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EEB05134.1 - 0.00097 17.5 0.1 0.093 11.0 0.0 2.8 3 0 0 3 3 3 2 Firmicute fructose-1,6-bisphosphatase OSCP PF00213.18 EEB05135.1 - 3e-45 154.4 4.1 3.5e-45 154.2 4.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PGM_PMM_I PF02878.16 EEB05136.1 - 1.6e-41 141.3 0.0 2.6e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EEB05136.1 - 8e-23 81.0 0.0 2.1e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEB05136.1 - 1.7e-15 57.2 0.0 3.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EEB05136.1 - 0.0002 21.5 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Peptidase_C14 PF00656.22 EEB05137.2 - 3.8e-67 226.9 0.0 4.6e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ATP-synt_ab PF00006.25 EEB05138.2 - 7.8e-65 218.5 0.0 1.2e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EEB05138.2 - 1.1e-13 51.5 0.5 2.6e-13 50.3 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 EEB05138.2 - 0.067 12.1 0.0 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) TPR_17 PF13431.6 EEB05139.1 - 1.3e-05 25.2 0.6 7.6 7.2 0.0 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05139.1 - 1.7e-05 25.2 7.8 0.041 14.4 3.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05139.1 - 4.3e-05 24.0 16.0 0.21 12.5 0.4 6.8 4 2 3 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB05139.1 - 0.00031 20.9 11.3 0.28 11.4 1.6 5.2 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEB05139.1 - 0.00031 20.7 10.3 3.7 8.0 0.0 7.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEB05139.1 - 0.00083 19.0 3.3 0.35 10.6 0.1 4.1 3 1 1 4 4 4 2 TPR repeat TPR_20 PF14561.6 EEB05139.1 - 0.0012 19.2 4.2 0.13 12.6 0.1 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05139.1 - 0.0019 17.9 1.4 19 5.3 0.4 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05139.1 - 0.014 15.7 10.1 0.11 12.8 2.8 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEB05139.1 - 0.015 15.4 1.5 0.32 11.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EEB05139.1 - 0.025 13.8 3.9 0.25 10.5 2.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EEB05139.1 - 0.066 12.9 2.8 0.1 12.3 0.2 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 EEB05139.1 - 0.2 12.3 6.8 18 6.0 0.2 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05139.1 - 0.51 10.6 18.5 4.2 7.7 0.5 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1774 PF08611.10 EEB05140.1 - 3.1e-21 75.5 3.5 3.1e-21 75.5 3.5 3.1 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) DUF3087 PF11286.8 EEB05140.1 - 0.43 10.0 9.7 0.64 9.5 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DUF373 PF04123.13 EEB05140.1 - 7.9 5.8 19.1 0.046 13.2 4.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF373) TPR_1 PF00515.28 EEB05141.1 - 8.1e-39 129.9 28.3 1.1e-07 31.4 0.4 14.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05141.1 - 6.1e-35 116.5 41.5 1.5e-07 31.0 0.4 15.3 17 0 0 17 17 15 7 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05141.1 - 1.3e-26 92.9 19.0 0.00023 21.6 0.0 10.9 8 3 3 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05141.1 - 2e-22 77.5 32.5 2e-06 27.6 0.2 13.0 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05141.1 - 1.4e-21 76.5 35.3 6.5e-08 32.7 0.1 10.5 11 2 4 15 15 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05141.1 - 2.6e-18 65.1 27.1 0.00066 20.3 0.1 13.9 11 5 5 16 16 14 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05141.1 - 4.8e-15 55.9 21.5 0.0079 16.8 0.0 10.6 10 2 2 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05141.1 - 1.3e-14 53.7 29.1 0.0013 19.3 0.1 10.8 12 0 0 12 12 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB05141.1 - 5.5e-12 45.7 25.7 1.9e-05 24.8 0.4 7.2 6 2 2 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EEB05141.1 - 7.2e-12 44.8 24.4 1.1e-05 25.1 0.2 9.8 11 0 0 11 11 11 2 TPR repeat TPR_7 PF13176.6 EEB05141.1 - 5.2e-11 41.8 20.8 0.0029 17.5 0.2 10.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05141.1 - 8.2e-10 38.4 15.2 0.88 10.1 0.0 10.6 13 0 0 13 13 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEB05141.1 - 4.6e-09 35.9 32.8 0.0036 17.1 0.1 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat ST7 PF04184.12 EEB05141.1 - 0.0061 15.1 0.1 0.015 13.8 0.1 1.6 1 0 0 1 1 1 1 ST7 protein PPR PF01535.20 EEB05141.1 - 0.018 15.2 3.2 12 6.4 0.1 5.0 4 0 0 4 4 4 0 PPR repeat DUF412 PF04217.13 EEB05141.1 - 0.032 14.1 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF412 TPR_4 PF07721.14 EEB05141.1 - 0.12 13.1 3.5 5.4 7.9 0.0 4.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TFIIA PF03153.13 EEB05141.1 - 3.1 7.7 28.3 5.9 6.8 28.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIT PF04212.18 EEB05141.1 - 3.5 7.8 29.5 7.1 6.8 0.4 8.9 9 1 0 9 9 9 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EEB05141.1 - 7.4 6.7 24.6 2.7 8.1 0.3 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat CAP_GLY PF01302.25 EEB05142.1 - 6.4e-23 80.6 0.3 1.7e-22 79.2 0.3 1.7 1 0 0 1 1 1 1 CAP-Gly domain DUF3800 PF12686.7 EEB05142.1 - 0.65 10.6 2.0 69 4.1 1.8 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) AhpC-TSA PF00578.21 EEB05143.1 - 3.1e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family CK_II_beta PF01214.18 EEB05144.2 - 4.6e-81 271.0 0.0 5.9e-81 270.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.13 EEB05145.1 - 9.8e-32 110.3 1.6 2.8e-31 108.8 1.6 1.8 1 1 0 1 1 1 1 RIC1 GRIP PF01465.20 EEB05146.1 - 3.2e-10 39.7 0.1 1e-09 38.1 0.1 2.0 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 EEB05146.1 - 0.0015 17.5 7.6 0.0015 17.5 7.6 5.9 2 2 3 5 5 5 3 Spc7 kinetochore protein Yuri_gagarin PF15934.5 EEB05146.1 - 0.0032 17.4 7.5 0.0032 17.4 7.5 5.1 3 2 0 4 4 4 2 Yuri gagarin HrpB7 PF09486.10 EEB05146.1 - 9.1 6.7 57.1 1.6 9.1 18.5 4.8 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) RRM_2 PF04059.12 EEB05147.2 - 2.9e-51 171.6 1.5 5.3e-51 170.8 1.5 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EEB05147.2 - 4.8e-14 51.9 0.7 3.8e-06 26.6 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EEB05147.2 - 0.14 12.4 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 CSTF_C PF14304.6 EEB05148.1 - 0.0015 18.1 0.5 0.0025 17.4 0.5 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal LSM PF01423.22 EEB05149.1 - 5.7e-19 67.6 0.5 7.7e-19 67.2 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB05149.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain CATSPERD PF15020.6 EEB05149.1 - 0.22 9.8 0.1 0.27 9.5 0.1 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta AA_permease PF00324.21 EEB05151.1 - 6e-129 430.7 35.7 6.9e-129 430.5 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB05151.1 - 1.5e-40 139.3 41.1 2e-40 138.9 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.21 EEB05151.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.6 5 0 0 5 5 5 0 Synaptobrevin Pkinase PF00069.25 EEB05152.1 - 4.4e-76 255.7 0.0 5e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05152.1 - 3.3e-31 108.5 0.0 5.7e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05152.1 - 3.3e-05 23.3 0.2 0.00044 19.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEB05152.1 - 0.0031 16.5 0.5 0.053 12.5 0.5 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEB05152.1 - 0.026 14.4 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEB05152.1 - 0.057 12.5 0.2 0.14 11.2 0.1 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EEB05152.1 - 0.15 10.8 0.1 0.33 9.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase COX6C PF02937.15 EEB05153.1 - 0.2 11.8 0.3 4.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc ANTH PF07651.16 EEB05154.2 - 6.7e-76 254.9 0.2 6.7e-76 254.9 0.2 4.1 2 1 2 5 5 5 1 ANTH domain I_LWEQ PF01608.17 EEB05154.2 - 1.4e-53 181.3 10.3 1.4e-53 181.3 10.3 6.7 4 2 1 5 5 5 1 I/LWEQ domain Spc7 PF08317.11 EEB05154.2 - 0.0023 16.9 22.3 0.0023 16.9 22.3 5.2 3 1 2 5 5 5 1 Spc7 kinetochore protein TcdB_N PF12918.7 EEB05154.2 - 0.0048 17.2 1.6 0.0048 17.2 1.6 3.4 2 2 2 4 4 4 1 TcdB toxin N-terminal helical domain DUF5388 PF17363.2 EEB05154.2 - 3.1 8.1 7.8 1.4 9.2 0.6 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5388) DNA_pol_B PF00136.21 EEB05155.1 - 1.6e-105 353.5 0.0 2.2e-105 353.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEB05155.1 - 6.1e-25 88.1 0.7 1.7e-13 50.4 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EEB05155.1 - 3.6e-08 33.8 11.0 3.6e-08 33.8 11.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Mito_carr PF00153.27 EEB05156.1 - 2.5e-73 242.1 0.8 4.7e-25 87.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.18 EEB05157.1 - 4.8e-46 154.8 7.0 7.5e-46 154.1 7.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Med12 PF09497.10 EEB05158.1 - 5.8e-26 90.6 0.2 2.8e-25 88.4 0.2 2.3 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Cnd1 PF12717.7 EEB05158.1 - 0.0038 17.3 2.3 0.68 10.0 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Slx4 PF09494.10 EEB05160.1 - 1.5e-12 47.3 0.0 3.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Ish1 PF10281.9 EEB05160.1 - 0.0045 17.3 0.7 4.7 7.6 0.0 2.9 2 1 1 3 3 3 2 Putative stress-responsive nuclear envelope protein GST_N PF02798.20 EEB05161.1 - 1.9e-17 63.4 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEB05161.1 - 4e-11 43.2 0.0 7.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEB05161.1 - 5.2e-10 39.4 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EEB05161.1 - 5.7e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEB05161.1 - 0.0007 19.7 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB05161.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 EEB05162.1 - 1.1e-22 80.9 0.3 1.8e-22 80.2 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EEB05162.1 - 4.2e-21 74.3 0.0 7.4e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EEB05162.1 - 5.5e-05 22.5 0.0 0.02 14.2 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 TFIIE_beta PF02186.15 EEB05163.1 - 2.5e-21 75.7 0.8 5.2e-21 74.7 0.8 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EEB05163.1 - 1.9e-19 69.1 1.1 1e-18 66.7 1.1 2.2 1 1 0 1 1 1 1 TFA2 Winged helix domain 2 Clr5 PF14420.6 EEB05164.2 - 1.2e-07 31.8 2.5 1.2e-07 31.8 2.5 2.6 3 0 0 3 3 3 1 Clr5 domain Vel1p PF10339.9 EEB05165.1 - 1.9e-110 366.9 2.5 2.1e-110 366.8 2.5 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive DUF4646 PF15496.6 EEB05166.1 - 3.8e-33 114.7 0.0 1e-32 113.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 EEB05166.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fungal_trans PF04082.18 EEB05167.1 - 2.6e-25 89.0 2.7 6.4e-25 87.7 2.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEB05167.1 - 1.2e-09 38.1 11.5 0.0006 20.1 5.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB05167.1 - 4.8e-07 30.1 10.2 0.011 16.5 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEB05167.1 - 0.00044 20.6 1.4 0.00044 20.6 1.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 EEB05167.1 - 0.062 13.2 0.2 0.062 13.2 0.2 2.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 EEB05167.1 - 0.11 12.9 8.4 0.69 10.4 0.1 3.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 EEB05167.1 - 0.13 11.4 1.0 0.24 10.6 1.0 1.3 1 0 0 1 1 1 0 Putative actin-like family DUF629 PF04780.12 EEB05167.1 - 0.2 10.1 2.1 0.42 9.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 EEB05167.1 - 0.69 10.0 2.3 3.6 7.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEB05167.1 - 2.9 8.3 10.0 2.8 8.3 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 EEB05167.1 - 9.4 6.0 6.3 32 4.3 0.1 2.7 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain GRAM PF02893.20 EEB05168.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 EEB05168.1 - 0.00024 21.2 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 RuvB_C PF05491.13 EEB05168.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Hydrolase_4 PF12146.8 EEB05169.2 - 0.00087 18.6 0.0 0.044 13.0 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEB05169.2 - 0.012 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EEB05169.2 - 0.027 14.0 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L35Ae PF01247.18 EEB05170.1 - 3.7e-41 139.2 0.2 4.1e-41 139.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EEB05170.1 - 0.0011 19.1 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain zf-Mss51 PF13824.6 EEB05171.1 - 0.089 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PLDc_2 PF13091.6 EEB05172.1 - 2.7e-16 59.7 0.1 9.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EEB05172.1 - 4.9e-06 26.5 0.9 0.031 14.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Pkinase PF00069.25 EEB05173.1 - 2.3e-78 263.2 0.5 1.2e-38 133.0 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EEB05173.1 - 7e-61 206.0 11.8 7e-61 206.0 11.8 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EEB05173.1 - 6.1e-49 166.6 0.4 9.1e-21 74.3 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EEB05173.1 - 1e-19 70.9 2.1 2.3e-18 66.6 0.2 3.5 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.6 EEB05173.1 - 3.2e-12 46.4 0.0 6.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EEB05173.1 - 7.9e-07 28.7 0.0 0.016 14.5 0.0 2.8 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EEB05173.1 - 4.5e-05 22.9 0.0 0.13 11.6 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB05173.1 - 0.00011 21.9 0.1 2.3 7.8 0.0 3.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB05173.1 - 0.0011 19.0 3.5 0.042 13.8 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family NAP PF00956.18 EEB05174.1 - 3.8e-17 62.4 20.1 1.1e-15 57.5 8.2 3.4 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) CENP-B_dimeris PF09026.10 EEB05174.1 - 1.8 9.0 10.5 1.3 9.4 8.3 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EEB05174.1 - 5.1 7.4 11.4 0.76 10.0 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Syntaxin-6_N PF09177.11 EEB05175.2 - 1.4e-15 57.6 2.9 3.3e-15 56.4 0.2 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal NPV_P10 PF05531.12 EEB05175.2 - 0.0018 18.7 1.3 0.3 11.6 0.0 2.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.8 EEB05175.2 - 0.0032 16.9 0.8 0.0032 16.9 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) DUF1664 PF07889.12 EEB05175.2 - 0.0085 16.1 2.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Sec34 PF04136.15 EEB05175.2 - 0.014 15.3 0.9 0.062 13.2 0.1 2.2 2 0 0 2 2 2 0 Sec34-like family MukF_M PF17192.4 EEB05175.2 - 0.028 14.2 8.9 0.072 12.8 2.1 2.7 1 1 1 3 3 3 0 MukF middle domain UPF0449 PF15136.6 EEB05175.2 - 0.092 13.2 0.6 0.092 13.2 0.6 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 CorA PF01544.18 EEB05175.2 - 0.52 9.6 3.5 0.9 8.8 2.7 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WEMBL PF05701.11 EEB05176.2 - 0.0013 17.5 2.7 0.0017 17.1 2.7 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Val_tRNA-synt_C PF10458.9 EEB05176.2 - 0.0023 18.2 1.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Cob_adeno_trans PF01923.18 EEB05176.2 - 0.0045 17.1 0.2 0.0082 16.3 0.1 1.4 1 1 0 1 1 1 1 Cobalamin adenosyltransferase DUF1640 PF07798.11 EEB05176.2 - 0.0057 16.7 1.6 0.1 12.7 1.6 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3958 PF13125.6 EEB05176.2 - 0.04 14.1 3.4 0.089 13.0 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Seryl_tRNA_N PF02403.22 EEB05176.2 - 0.041 14.1 0.5 0.041 14.1 0.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4618 PF15397.6 EEB05176.2 - 0.042 13.3 5.6 0.14 11.5 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) APG17 PF04108.12 EEB05176.2 - 0.09 11.9 8.1 0.097 11.8 6.8 1.6 1 1 1 2 2 2 0 Autophagy protein Apg17 YlqD PF11068.8 EEB05176.2 - 0.27 11.6 3.0 0.64 10.4 1.4 2.2 1 1 1 2 2 2 0 YlqD protein DUF16 PF01519.16 EEB05176.2 - 0.49 10.9 4.3 2 9.0 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 IFP_35_N PF07334.13 EEB05176.2 - 0.76 9.9 5.2 0.28 11.3 0.9 2.3 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FYVE PF01363.21 EEB05177.1 - 2.1e-21 75.9 6.6 2.1e-21 75.9 6.6 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EEB05177.1 - 1.2e-06 28.8 2.5 1.2e-06 28.8 2.5 4.0 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 EEB05177.1 - 0.00021 21.0 4.7 0.00021 21.0 4.7 3.0 2 0 0 2 2 2 1 RING-like zinc finger IBR PF01485.21 EEB05177.1 - 0.015 15.5 6.6 0.015 15.5 6.6 3.6 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 EEB05177.1 - 0.027 14.1 2.8 0.027 14.1 2.8 3.4 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 EEB05177.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF4428 PF14471.6 EEB05177.1 - 3.9 7.5 0.0 3.9 7.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) Dus PF01207.17 EEB05178.1 - 8.8e-71 238.5 0.0 1.1e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cut8 PF08559.10 EEB05178.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein DHO_dh PF01180.21 EEB05178.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DnaJ PF00226.31 EEB05179.1 - 7.1e-16 58.1 0.8 1.6e-15 57.0 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EEB05179.1 - 3.1e-11 43.0 0.0 2.8e-08 33.2 0.0 2.6 1 1 1 2 2 2 2 Sec63 Brl domain Svf1_C PF17187.4 EEB05180.1 - 3.1e-26 92.2 0.0 4.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EEB05180.1 - 1.2e-14 54.7 0.1 1.8e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Peptidase_M4 PF01447.18 EEB05180.1 - 0.033 14.7 0.1 0.057 13.9 0.1 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Rad60-SLD PF11976.8 EEB05181.1 - 3.2e-26 91.0 0.1 1e-17 63.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEB05181.1 - 1e-07 31.6 0.1 0.0008 19.1 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD_2 PF13881.6 EEB05181.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRM_9 PF18444.1 EEB05182.1 - 3.8e-21 74.7 0.0 7.6e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 EEB05182.1 - 1.5e-20 72.5 0.3 5.2e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 EEB05182.1 - 4.1e-08 32.9 0.0 7.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EEB05182.1 - 0.00097 18.9 1.5 0.0039 16.9 1.5 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EEB05182.1 - 0.0046 17.3 5.7 0.011 16.2 0.9 2.7 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) NTF2 PF02136.20 EEB05182.1 - 0.036 14.6 0.0 0.089 13.4 0.0 1.8 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain RAWUL PF16207.5 EEB05182.1 - 0.13 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like UBA_4 PF14555.6 EEB05182.1 - 0.16 11.8 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain GST_N PF02798.20 EEB05183.1 - 6.9e-19 68.0 0.0 1.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEB05183.1 - 1.2e-13 51.2 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEB05183.1 - 4e-11 43.0 0.0 8.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEB05183.1 - 5.4e-10 39.4 0.0 1.2e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEB05183.1 - 2.1e-08 34.3 0.0 4.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB05183.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M1 PF01433.20 EEB05184.1 - 5.6e-83 277.8 1.3 9.5e-83 277.1 0.9 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EEB05184.1 - 1.4e-78 264.7 0.4 2.3e-78 263.9 0.4 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EEB05184.1 - 5.8e-51 173.3 0.2 1.1e-50 172.4 0.1 1.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Glyco_transf_20 PF00982.21 EEB05185.1 - 5.1e-153 510.2 0.0 7.4e-153 509.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEB05185.1 - 1.8e-35 122.2 0.0 3.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.6 EEB05185.1 - 0.00038 20.9 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Galactosyl_T PF01762.21 EEB05186.1 - 8.5e-08 32.2 1.3 0.00078 19.3 0.3 3.2 2 1 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 EEB05186.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like AAA_14 PF13173.6 EEB05186.1 - 0.078 13.0 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF1325 PF07039.11 EEB05187.1 - 2.1e-33 115.2 0.0 4.6e-33 114.1 0.0 1.5 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.6 EEB05187.1 - 0.0022 18.0 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Agenet PF05641.12 EEB05187.1 - 0.0094 16.4 0.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 Agenet domain Peptidase_S24 PF00717.23 EEB05187.1 - 0.13 12.3 0.1 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 Peptidase S24-like BAR PF03114.18 EEB05188.1 - 4.4e-59 200.0 3.9 6e-59 199.6 3.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EEB05188.1 - 6.6e-14 51.3 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB05188.1 - 1.3e-11 44.2 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB05188.1 - 1.2e-08 34.4 0.0 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BRE1 PF08647.11 EEB05188.1 - 0.0077 16.3 2.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase CT_C_D PF02682.16 EEB05188.1 - 0.017 14.9 0.7 0.029 14.1 0.7 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D SH3_10 PF17902.1 EEB05188.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Aminotran_5 PF00266.19 EEB05189.1 - 7.5e-90 301.6 0.0 9e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEB05189.1 - 4.6e-07 29.5 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEB05189.1 - 1.6e-06 27.6 0.1 2.6e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 EEB05189.1 - 0.075 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.19 EEB05189.1 - 0.15 12.1 0.1 1.9 8.6 0.0 2.4 2 1 0 2 2 2 0 B12 binding domain Bromodomain PF00439.25 EEB05190.1 - 1.7e-15 56.8 0.1 7.2e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Bromodomain DUF2849 PF11011.8 EEB05190.1 - 0.1 13.3 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) zf-RING_2 PF13639.6 EEB05191.1 - 5.2e-09 36.3 8.3 1.7e-08 34.7 8.3 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EEB05191.1 - 5.3e-07 29.7 5.4 1.4e-06 28.3 5.4 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EEB05191.1 - 1.5e-06 28.4 7.3 3.8e-06 27.1 7.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEB05191.1 - 3e-06 27.0 9.5 8.8e-06 25.5 9.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB05191.1 - 5.4e-06 26.1 8.4 1.4e-05 24.8 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEB05191.1 - 6.8e-06 26.0 2.5 2e-05 24.6 2.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EEB05191.1 - 0.0022 17.6 6.0 0.0047 16.5 6.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EEB05191.1 - 0.0092 15.7 3.9 0.023 14.4 3.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EEB05191.1 - 0.017 15.1 4.7 0.04 14.0 4.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 EEB05191.1 - 0.024 14.8 7.6 0.049 13.8 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain Bromo_TP_like PF17027.5 EEB05191.1 - 0.063 13.4 0.2 0.063 13.4 0.2 2.5 2 0 0 2 2 2 0 Histone-fold protein zf-C3HC4_3 PF13920.6 EEB05191.1 - 0.2 11.6 6.4 0.49 10.3 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EEB05191.1 - 0.36 11.2 8.2 0.84 10.0 8.2 1.7 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 EEB05191.1 - 1.4 8.9 8.3 0.41 10.6 4.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 EEB05191.1 - 1.4 8.9 6.6 3.2 7.7 6.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EEB05191.1 - 1.4 8.8 4.0 12 5.8 4.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EEB05191.1 - 3 7.7 10.1 1.1 9.2 6.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EEB05191.1 - 3.2 7.8 8.4 7.2 6.7 8.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 EEB05191.1 - 6.5 6.7 7.1 13 5.8 7.1 1.5 1 0 0 1 1 1 0 PHD-finger DUF218 PF02698.17 EEB05193.1 - 7.8e-07 29.2 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain WD40 PF00400.32 EEB05195.1 - 3.3e-45 151.1 21.6 1.4e-07 32.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EEB05195.1 - 3.2e-16 58.9 2.1 8.3e-16 57.6 2.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEB05195.1 - 2.2e-11 43.3 2.2 5.1e-11 42.2 2.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EEB05195.1 - 3.9e-10 39.0 7.3 0.0021 16.8 0.8 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEB05195.1 - 1.5e-07 31.6 0.1 0.035 14.4 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EEB05195.1 - 5.5e-05 23.0 0.2 0.00045 20.1 0.0 2.7 3 0 0 3 3 3 1 F-box WD40_like PF17005.5 EEB05195.1 - 0.00023 20.6 0.1 0.041 13.2 0.1 2.5 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 EEB05195.1 - 0.00025 21.0 0.0 0.12 12.4 0.0 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EEB05195.1 - 0.0055 15.5 0.3 0.2 10.4 0.0 2.5 2 1 0 2 2 2 1 Nup133 N terminal like PRANC PF09372.10 EEB05195.1 - 0.03 14.7 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 PRANC domain La PF05383.17 EEB05197.1 - 7.1e-24 83.6 0.0 1.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EEB05197.1 - 0.0008 19.2 0.5 0.0015 18.3 0.5 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Selenoprotein_S PF06936.11 EEB05197.1 - 5.5 6.8 7.9 0.66 9.8 1.1 2.4 2 1 1 3 3 3 0 Selenoprotein S (SelS) CHCH PF06747.13 EEB05198.2 - 1.4e-06 28.3 6.3 2.7e-06 27.4 6.3 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EEB05198.2 - 0.00073 19.9 3.5 0.00073 19.9 3.5 2.0 2 0 0 2 2 2 1 GCK domain DHO_dh PF01180.21 EEB05199.1 - 1.4e-94 316.6 0.0 1.7e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EEB05199.1 - 0.0021 17.1 0.0 0.007 15.4 0.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EEB05199.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase DNA_ligase_A_M PF01068.21 EEB05200.1 - 4.2e-66 222.5 0.0 8.4e-66 221.5 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEB05200.1 - 1.1e-45 156.1 0.1 1.8e-45 155.4 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EEB05200.1 - 1.2e-23 83.6 0.0 3e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EEB05200.1 - 4.6e-06 27.0 0.0 8.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DDHD PF02862.17 EEB05201.1 - 4.7e-44 151.2 0.4 6.6e-43 147.4 0.3 2.5 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.14 EEB05201.1 - 0.029 13.9 0.1 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.15 EEB05201.1 - 0.048 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Rib_hydrolayse PF02267.17 EEB05201.1 - 0.16 11.3 0.6 0.27 10.6 0.6 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase MFS_1 PF07690.16 EEB05202.1 - 3.3e-35 121.7 41.2 1.9e-32 112.6 44.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEB05202.1 - 0.0003 20.2 25.4 0.00086 18.7 25.4 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 EEB05202.1 - 0.087 12.3 0.1 0.087 12.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Rrn6 PF10214.9 EEB05203.1 - 8.9e-46 156.8 9.2 2.2e-36 125.8 0.4 2.2 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor FAD_binding_2 PF00890.24 EEB05204.1 - 2.1e-75 254.4 0.1 2.5e-75 254.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EEB05204.1 - 3.6e-07 29.7 0.5 1.9e-06 27.4 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEB05204.1 - 3.8e-07 29.8 0.1 5.8e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EEB05204.1 - 4.7e-07 29.7 0.4 1.1e-05 25.3 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEB05204.1 - 3.2e-05 24.1 1.3 8.8e-05 22.7 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EEB05204.1 - 3.4e-05 23.2 0.1 5.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EEB05204.1 - 0.00059 19.0 3.8 0.0015 17.7 1.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 EEB05204.1 - 0.00096 18.0 10.0 0.0012 17.6 1.8 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 EEB05204.1 - 0.0075 15.6 0.4 0.011 15.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EEB05204.1 - 0.053 12.7 3.5 0.12 11.6 0.9 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EEB05204.1 - 0.089 12.0 0.0 0.81 8.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Vps8 PF12816.7 EEB05205.1 - 1.7e-34 119.1 4.7 6.9e-34 117.1 3.8 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 MPS2 PF17060.5 EEB05206.1 - 0.0099 15.2 3.3 0.01 15.1 3.3 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 FAM76 PF16046.5 EEB05207.1 - 2.2 7.5 15.4 0.041 13.2 6.6 1.9 2 0 0 2 2 2 0 FAM76 protein ABC_tran_Xtn PF12848.7 EEB05207.1 - 5.8 7.0 12.6 0.94 9.6 6.8 2.5 2 0 0 2 2 2 0 ABC transporter Csm1 PF12539.8 EEB05208.2 - 5.7e-17 62.1 0.4 1.3e-16 61.0 0.1 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 EEB05208.2 - 3.6e-05 24.0 7.3 8e-05 22.8 7.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5094) BLOC1_2 PF10046.9 EEB05208.2 - 0.011 16.0 2.7 0.24 11.7 0.8 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 EEB05208.2 - 0.018 15.3 7.9 0.044 14.0 7.9 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 EEB05208.2 - 0.02 12.8 1.4 0.025 12.5 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 EEB05208.2 - 0.027 14.5 1.4 0.05 13.6 1.4 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF2201_N PF13203.6 EEB05208.2 - 0.027 14.1 0.3 0.044 13.4 0.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Spc24 PF08286.11 EEB05208.2 - 0.032 14.4 2.9 0.032 14.4 2.9 2.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 SHE3 PF17078.5 EEB05208.2 - 0.034 13.9 10.2 0.097 12.4 0.2 2.4 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 EEB05208.2 - 0.055 13.8 8.0 1.1 9.7 0.4 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain APG6_N PF17675.1 EEB05208.2 - 0.12 12.9 9.2 0.26 11.8 9.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EEB05208.2 - 0.14 11.7 4.8 0.2 11.2 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCU PF04678.13 EEB05208.2 - 0.16 12.0 2.3 0.27 11.3 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UQ_con PF00179.26 EEB05209.2 - 2.8e-45 153.4 0.0 3.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEB05209.2 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEB05209.2 - 0.059 13.7 0.0 0.079 13.3 0.0 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 EEB05209.2 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain Zn_ribbon_17 PF17120.5 EEB05210.1 - 2.1e-09 36.9 11.3 2.1e-09 36.9 11.3 2.4 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EEB05210.1 - 2.3e-05 25.0 18.4 0.037 14.9 0.2 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.22 EEB05210.1 - 0.018 15.3 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 RWD domain Sgf11 PF08209.11 EEB05210.1 - 0.028 14.0 1.2 0.1 12.1 0.7 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-rbx1 PF12678.7 EEB05210.1 - 0.29 11.5 6.6 0.91 9.9 6.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEB05210.1 - 0.61 10.2 8.4 2.1 8.5 8.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHF5 PF03660.14 EEB05210.1 - 0.78 10.0 10.5 0.31 11.3 7.2 2.0 2 0 0 2 2 2 0 PHF5-like protein zf-CCHC_2 PF13696.6 EEB05210.1 - 2.6 8.0 10.1 0.066 13.1 2.2 2.3 2 0 0 2 2 2 0 Zinc knuckle RecR PF02132.15 EEB05210.1 - 3.1 7.5 6.2 0.27 10.8 0.5 2.2 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 EEB05210.1 - 9.4 6.3 11.5 29 4.8 11.5 1.9 1 0 0 1 1 1 0 Double zinc ribbon SRF-TF PF00319.18 EEB05211.1 - 7.3e-19 67.0 0.2 1.2e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.14 EEB05212.1 - 2.4e-13 49.9 7.1 3.1e-13 49.5 7.1 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EEB05212.1 - 1.9 8.6 18.8 0.58 10.3 0.9 3.6 2 2 1 3 3 3 0 EamA-like transporter family vATP-synt_E PF01991.18 EEB05213.1 - 8e-59 198.4 7.3 9.7e-59 198.1 7.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit IL32 PF15225.6 EEB05213.1 - 0.0034 17.7 0.1 0.0093 16.3 0.1 1.7 1 0 0 1 1 1 1 Interleukin 32 Virulence_fact PF13769.6 EEB05213.1 - 0.036 14.3 0.2 0.078 13.2 0.2 1.6 1 0 0 1 1 1 0 Virulence factor TF_AP-2 PF03299.14 EEB05213.1 - 0.11 12.5 3.8 0.15 12.0 3.8 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 Nse5 PF08691.10 EEB05214.1 - 1.1e-174 581.9 0.3 1.2e-174 581.8 0.3 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 VSG_B PF13206.6 EEB05214.1 - 0.45 9.7 7.2 0.14 11.4 3.3 1.9 2 0 0 2 2 2 0 Trypanosomal VSG domain Spore_II_R PF09551.10 EEB05214.1 - 6.3 7.3 6.5 4.5 7.8 1.8 2.4 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Y_phosphatase PF00102.27 EEB05215.1 - 3.6e-66 223.1 0.0 4.4e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEB05215.1 - 4.1e-05 23.8 0.0 8.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EEB05215.1 - 7e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EEB05215.1 - 0.00033 20.7 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 EEB05215.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Nore1-SARAH PF16517.5 EEB05215.1 - 0.55 10.2 4.6 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain VanZ PF04892.12 EEB05216.1 - 1.1e-06 29.4 5.9 1.7e-06 28.7 5.9 1.4 1 1 0 1 1 1 1 VanZ like family Sec7 PF01369.20 EEB05217.2 - 9.5e-24 84.1 0.1 1.6e-22 80.1 0.0 2.2 1 1 1 2 2 2 1 Sec7 domain PH_9 PF15410.6 EEB05217.2 - 6e-07 29.8 1.2 8.5e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EEB05217.2 - 0.0054 17.2 0.1 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 PH domain 2Fe-2S_thioredx PF01257.19 EEB05218.2 - 9.6e-24 83.9 0.0 9.6e-24 83.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin SCP1201-deam PF14428.6 EEB05218.2 - 0.0097 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 SCP1.201-like deaminase Glyco_hydro_72 PF03198.14 EEB05219.1 - 1.2e-141 471.5 5.0 1.6e-141 471.1 5.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EEB05219.1 - 7.9e-06 25.5 0.1 0.0001 21.8 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3808 PF10300.9 EEB05220.1 - 3.8e-95 319.4 3.6 4.6e-95 319.1 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.6 EEB05220.1 - 0.0014 18.7 0.3 0.014 15.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05220.1 - 0.0036 17.3 0.1 0.039 14.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05220.1 - 0.0069 16.2 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Ribosomal_L22e PF01776.17 EEB05221.1 - 3.2e-46 156.2 1.4 4.1e-46 155.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family 2OG-FeII_Oxy_2 PF13532.6 EEB05222.1 - 2.3e-13 50.8 0.0 3e-12 47.1 0.0 2.1 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zip PF02535.22 EEB05223.1 - 1.5e-45 155.9 16.1 1.5e-45 155.9 16.1 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter HSP9_HSP12 PF04119.12 EEB05224.1 - 4.8e-24 84.5 8.2 4.8e-24 84.5 8.2 1.9 1 1 1 2 2 2 1 Heat shock protein 9/12 DUF3958 PF13125.6 EEB05224.1 - 0.024 14.8 0.2 0.026 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) YtxH PF12732.7 EEB05224.1 - 0.07 13.7 7.8 0.13 12.9 7.8 1.5 1 1 0 1 1 1 0 YtxH-like protein MT0933_antitox PF14013.6 EEB05224.1 - 0.37 11.1 8.7 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein DAHP_synth_1 PF00793.20 EEB05225.1 - 5.3e-100 333.8 0.0 6.4e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.24 EEB05226.1 - 5e-11 42.2 21.9 7.9e-07 28.8 2.7 3.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EEB05226.1 - 5.2e-06 26.2 0.0 8.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EEB05226.1 - 0.011 15.8 2.9 0.011 15.8 2.9 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_3 PF15663.5 EEB05226.1 - 0.045 14.0 6.4 0.26 11.5 2.4 2.4 2 0 0 2 2 2 0 Zinc-finger containing family DUF2020 PF09449.10 EEB05226.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) N6-adenineMlase PF10237.9 EEB05226.1 - 0.082 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Torus PF16131.5 EEB05226.1 - 0.088 13.5 5.9 0.61 10.8 1.4 2.9 2 1 1 3 3 3 0 Torus domain GTP_EFTU PF00009.27 EEB05227.1 - 1.8e-05 24.4 0.0 0.12 11.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 EEB05228.1 - 2e-13 49.1 0.1 0.00011 21.9 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EEB05228.1 - 2.1e-13 48.8 0.4 4.6e-05 22.7 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EEB05228.1 - 1.8e-11 44.3 0.0 1.4e-06 28.6 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EEB05228.1 - 3.2e-08 33.8 0.0 4.9e-05 23.6 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EEB05228.1 - 4.9e-07 29.5 1.9 5.9e-05 22.8 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EEB05228.1 - 0.0014 18.0 8.0 0.0032 16.9 0.1 3.8 5 1 0 5 5 5 1 EF hand DUF3810 PF12725.7 EEB05228.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) HEAT PF02985.22 EEB05229.1 - 9.4e-43 140.6 26.6 0.0037 17.4 0.0 14.6 14 1 1 15 15 15 11 HEAT repeat HEAT_2 PF13646.6 EEB05229.1 - 2.5e-32 111.1 4.6 2.2e-10 40.8 0.0 7.3 2 1 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 EEB05229.1 - 6.3e-11 42.7 4.1 0.12 13.0 0.1 7.5 3 3 6 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EEB05229.1 - 2e-10 39.9 2.4 0.00076 18.2 0.0 3.8 2 1 2 4 4 4 4 Adaptin N terminal region Cnd1 PF12717.7 EEB05229.1 - 4.3e-10 39.9 7.4 0.16 12.0 0.0 5.4 2 1 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEB05229.1 - 2.3e-05 24.8 14.9 4.6 7.9 0.0 8.6 7 3 3 10 10 10 1 HEAT-like repeat IFRD PF05004.13 EEB05229.1 - 0.0012 18.0 0.1 0.6 9.2 0.0 3.6 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 EEB05229.1 - 0.0023 17.9 0.3 37 4.6 0.0 6.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat PRELI PF04707.14 EEB05230.2 - 2.2e-11 43.8 0.0 2.6e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family GTP1_OBG PF01018.22 EEB05231.2 - 1.5e-45 154.6 1.1 3.9e-33 114.2 0.6 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EEB05231.2 - 6.2e-23 81.1 0.0 1.5e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB05231.2 - 8.1e-12 44.9 0.0 2.1e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEB05231.2 - 0.00072 19.7 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Arf PF00025.21 EEB05231.2 - 0.002 17.6 0.1 0.012 15.1 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 EEB05231.2 - 0.013 16.0 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 EEB05231.2 - 0.024 14.2 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB05231.2 - 0.035 14.0 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EEB05231.2 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EEB05231.2 - 0.06 13.1 0.0 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EEB05231.2 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain cobW PF02492.19 EEB05231.2 - 0.16 11.6 0.2 4.7 6.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EEB05231.2 - 0.19 10.7 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sugar_tr PF00083.24 EEB05232.1 - 9.8e-29 100.5 32.3 1.7e-20 73.3 9.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEB05232.1 - 1.6e-19 70.1 44.9 6.6e-16 58.2 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.20 EEB05232.1 - 0.33 10.9 2.3 0.78 9.7 0.0 2.9 2 0 0 2 2 2 0 Syndecan domain EXS PF03124.14 EEB05233.1 - 1.6e-88 297.2 36.8 2.2e-88 296.8 36.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EEB05233.1 - 2.6e-15 57.2 13.0 4.6e-13 49.9 10.5 3.1 2 1 0 2 2 2 1 SPX domain Semialdhyde_dhC PF02774.18 EEB05234.1 - 5.2e-43 147.3 0.0 7.8e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EEB05234.1 - 8.1e-32 110.2 0.0 1.5e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EEB05234.1 - 0.0032 18.2 0.0 0.013 16.3 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 EEB05234.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus FAD_binding_6 PF00970.24 EEB05235.1 - 2.4e-32 111.2 0.0 3.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEB05235.1 - 2e-30 105.7 0.0 3.2e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EEB05235.1 - 1.6e-05 25.1 0.0 0.0059 16.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF3127 PF11325.8 EEB05235.1 - 0.16 12.2 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Mob1_phocein PF03637.17 EEB05236.1 - 6.9e-65 218.2 0.2 8.6e-65 217.9 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family SR-25 PF10500.9 EEB05236.1 - 3.3 7.3 10.6 4.6 6.8 10.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADH_N PF08240.12 EEB05237.1 - 5.1e-30 103.6 1.0 1e-29 102.6 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB05237.1 - 1.7e-19 70.1 0.1 2.9e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEB05237.1 - 2.7e-07 30.3 0.0 1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EEB05237.1 - 9.4e-05 23.5 0.0 0.00022 22.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EEB05237.1 - 0.0041 17.8 0.0 0.0093 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Prot_ATP_ID_OB PF16450.5 EEB05237.1 - 0.014 15.4 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain AlaDh_PNT_C PF01262.21 EEB05237.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEB05237.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 EEB05237.1 - 0.068 12.7 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EEB05237.1 - 0.074 13.7 0.1 0.25 12.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEB05237.1 - 0.15 12.8 0.0 0.45 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GST_N PF02798.20 EEB05238.1 - 4.8e-18 65.3 0.0 1.4e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEB05238.1 - 7.2e-13 48.8 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEB05238.1 - 1.3e-11 44.6 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEB05238.1 - 2.2e-11 43.8 0.1 5e-11 42.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEB05238.1 - 5.6e-10 39.3 0.1 1.2e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB05238.1 - 1.5e-08 34.5 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EEB05238.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GLEYA PF10528.9 EEB05239.1 - 2e-23 82.6 2.2 2e-23 82.6 2.2 3.7 3 0 0 3 3 3 1 GLEYA domain Fe-ADH PF00465.19 EEB05240.1 - 1.5e-126 422.1 2.4 1.7e-126 421.9 2.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEB05240.1 - 2e-21 76.9 2.7 5.4e-13 49.2 0.2 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Lamprin PF06403.11 EEB05240.1 - 0.028 14.4 0.2 0.071 13.1 0.2 1.6 1 0 0 1 1 1 0 Lamprin MCM PF00493.23 EEB05240.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Aldo_ket_red PF00248.21 EEB05241.1 - 3.3e-63 213.6 0.0 3.3e-61 207.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DpaA_N PF16924.5 EEB05241.1 - 0.03 14.4 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain tRNA-synt_1b PF00579.25 EEB05242.1 - 4.7e-73 246.1 0.3 6.9e-73 245.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Ada3 PF10198.9 EEB05242.1 - 0.057 13.6 1.4 0.098 12.8 1.4 1.4 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Transglut_i_TM PF14400.6 EEB05242.1 - 0.22 11.6 4.3 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices His_Phos_2 PF00328.22 EEB05243.2 - 1.8e-109 366.6 0.2 2.4e-109 366.2 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EEB05243.2 - 1e-36 124.9 0.0 2.3e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EEB05243.2 - 2.8e-06 27.1 0.0 7e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EEB05243.2 - 0.004 17.2 0.3 0.024 14.7 0.3 2.0 1 1 0 1 1 1 1 ATP-grasp domain Utp21 PF04192.12 EEB05244.1 - 8.3e-63 212.0 3.2 1.3e-62 211.3 3.2 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EEB05244.1 - 3.8e-16 59.2 19.1 2.5e-07 31.3 0.3 10.2 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05244.1 - 1.1e-13 51.3 2.0 0.00086 19.6 0.0 6.7 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB05244.1 - 1.2e-05 24.5 0.7 0.0086 15.1 0.0 3.7 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEB05244.1 - 0.0016 17.2 0.9 0.02 13.6 0.0 2.9 3 1 0 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 EEB05244.1 - 0.054 12.0 0.2 0.34 9.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Acetyltransf_1 PF00583.25 EEB05245.1 - 3.4e-13 49.9 0.0 4.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB05245.1 - 3.2e-10 40.3 0.2 6.1e-10 39.4 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEB05245.1 - 2.7e-09 37.0 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEB05245.1 - 0.0041 17.3 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Reg_prop PF07494.11 EEB05245.1 - 0.037 14.2 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 0 Two component regulator propeller Gemini_AL1 PF00799.20 EEB05246.2 - 0.017 15.4 1.2 0.035 14.5 1.2 1.5 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Seryl_tRNA_N PF02403.22 EEB05246.2 - 0.04 14.2 8.0 0.075 13.3 6.3 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RsdA_SigD_bd PF16751.5 EEB05246.2 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region E2F_CC-MB PF16421.5 EEB05246.2 - 0.88 10.0 4.3 6.1 7.3 0.6 2.9 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain DUF641 PF04859.12 EEB05246.2 - 1.9 8.8 8.2 0.81 10.0 2.7 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) PHP PF02811.19 EEB05247.1 - 3.8e-16 59.8 0.2 8.6e-16 58.7 0.1 1.6 2 0 0 2 2 2 1 PHP domain SF1-HH PF16275.5 EEB05248.1 - 4.3e-35 120.5 0.3 4.3e-35 120.5 0.3 3.1 3 0 0 3 3 3 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EEB05248.1 - 1.9e-11 43.5 10.3 1.9e-05 24.5 0.7 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EEB05248.1 - 4.7e-07 29.5 0.1 8.6e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EEB05248.1 - 6.8e-05 22.7 4.3 0.0017 18.3 1.2 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EEB05248.1 - 0.0079 16.0 4.2 0.56 10.1 0.3 3.2 1 1 1 2 2 2 2 Zinc knuckle PolC_DP2 PF03833.13 EEB05248.1 - 0.029 12.3 0.7 0.037 11.9 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_4 PF14392.6 EEB05248.1 - 0.044 13.5 6.2 0.45 10.3 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle UPF0167 PF03691.14 EEB05248.1 - 0.11 12.3 0.9 0.23 11.2 0.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-CCHC_2 PF13696.6 EEB05248.1 - 0.67 9.8 10.8 0.29 11.0 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 EEB05248.1 - 1.8 8.4 7.4 0.1 12.3 0.6 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger SOG2 PF10428.9 EEB05248.1 - 2.1 7.5 4.3 20 4.2 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein XPG_I_2 PF12813.7 EEB05249.1 - 1.1e-58 198.7 0.0 1.4e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 EEB05249.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 XPG I-region zf-CSL PF05207.13 EEB05250.1 - 1.3e-17 63.3 0.3 1.8e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EEB05250.1 - 1.3e-05 25.3 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Phos_pyr_kin PF08543.12 EEB05251.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EEB05251.1 - 3.6e-08 33.1 0.1 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Fcf1 PF04900.12 EEB05252.1 - 2.2e-36 124.2 0.2 4.2e-36 123.3 0.2 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EEB05252.1 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Ribosomal_L4 PF00573.22 EEB05252.1 - 0.0092 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Presenilin PF01080.17 EEB05252.1 - 1.5 7.5 4.5 1.9 7.2 4.5 1.1 1 0 0 1 1 1 0 Presenilin Asp PF00026.23 EEB05253.1 - 4.8e-53 180.6 10.2 6.1e-53 180.3 10.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEB05253.1 - 8.7e-15 55.4 2.1 9.3e-15 55.3 0.3 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEB05253.1 - 0.0019 18.8 0.1 1.2 9.8 0.0 3.4 2 1 1 3 3 3 1 Aspartyl protease DUF4203 PF13886.6 EEB05253.1 - 0.074 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Met_10 PF02475.16 EEB05254.1 - 4.9e-73 245.1 0.0 8.2e-73 244.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EEB05254.1 - 0.0035 16.6 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF4743 PF15916.5 EEB05254.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Pkinase PF00069.25 EEB05255.1 - 2.5e-53 181.1 0.0 4.2e-33 114.8 0.1 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05255.1 - 6.8e-23 81.3 0.0 1.9e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EEB05255.1 - 9e-05 22.6 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FTA2 PF13095.6 EEB05255.1 - 0.00079 19.1 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EEB05255.1 - 0.0028 16.5 0.1 0.0058 15.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEB05255.1 - 0.0078 15.6 0.2 4.4 6.5 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EEB05255.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB05255.1 - 0.16 11.8 0.1 0.59 10.0 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_11 PF08241.12 EEB05256.1 - 3.3e-05 24.5 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEB05256.1 - 0.00025 20.5 0.0 0.00071 19.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEB05256.1 - 0.00073 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB05256.1 - 0.0035 18.0 0.0 0.012 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB05256.1 - 0.075 13.8 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CCDC106 PF15794.5 EEB05256.1 - 3.2 7.4 9.0 7.7 6.2 9.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RRM_1 PF00076.22 EEB05258.1 - 1.1e-40 137.3 0.8 1.5e-20 72.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB05258.1 - 1.7e-06 28.0 0.0 0.024 14.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEB05258.1 - 0.0031 17.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Fer2_3 PF13085.6 EEB05259.2 - 3.8e-33 113.7 0.1 6.3e-33 113.0 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EEB05259.2 - 2.3e-09 37.6 7.0 2.3e-09 37.6 7.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EEB05259.2 - 3.5e-08 33.8 6.4 3.5e-08 33.8 6.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EEB05259.2 - 2.9e-07 30.5 4.1 2.9e-07 30.5 4.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EEB05259.2 - 0.3 11.1 8.0 0.049 13.6 2.8 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EEB05259.2 - 5.5 7.7 19.7 0.06 13.9 9.0 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EEB05259.2 - 8.7 6.6 17.3 0.4 10.9 8.4 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Arv1 PF04161.13 EEB05260.2 - 3.8e-58 197.1 8.9 5.4e-58 196.6 8.9 1.2 1 0 0 1 1 1 1 Arv1-like family F-box PF00646.33 EEB05261.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain LCE6A PF15858.5 EEB05262.1 - 0.61 10.9 3.4 15 6.4 0.7 2.7 2 0 0 2 2 2 0 Late cornified envelope protein 6A family Hamartin PF04388.12 EEB05262.1 - 2.1 6.9 8.2 2.5 6.7 8.2 1.2 1 0 0 1 1 1 0 Hamartin protein ALO PF04030.14 EEB05263.1 - 2.3e-68 230.9 3.2 3e-68 230.4 3.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EEB05263.1 - 1.1e-29 103.0 0.3 1.5e-29 102.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain GST_C_2 PF13410.6 EEB05263.1 - 0.34 11.0 1.4 2.6 8.1 0.2 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Aft1_HRA PF11786.8 EEB05264.1 - 9e-11 42.0 13.6 9e-11 42.0 13.6 3.5 2 1 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 EEB05264.1 - 5.2e-10 39.3 3.9 9.8e-10 38.4 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEB05264.1 - 3.6e-06 27.0 5.6 9.4e-06 25.6 5.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 EEB05264.1 - 0.002 18.5 1.1 0.002 18.5 1.1 4.3 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain C2 PF00168.30 EEB05265.2 - 1.8e-12 47.4 0.0 3.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain TMEM171 PF15471.6 EEB05265.2 - 0.53 9.2 2.0 0.37 9.7 0.5 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 MBF1 PF08523.10 EEB05266.1 - 5.6e-24 84.4 2.4 5.6e-24 84.4 2.4 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EEB05266.1 - 2.8e-14 52.9 0.2 5.2e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EEB05266.1 - 5.1e-06 26.7 0.2 1.2e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EEB05266.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 EEB05266.1 - 0.016 15.2 0.2 0.026 14.5 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 EEB05266.1 - 0.088 12.6 0.0 0.81 9.5 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3808 PF10300.9 EEB05267.1 - 2.9e-113 379.1 0.0 3.6e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF423 PF04241.15 EEB05267.1 - 0.12 12.6 0.1 0.41 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF423) RAB3GAP2_N PF14655.6 EEB05268.1 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DNA_pol3_delta2 PF13177.6 EEB05269.1 - 1.3e-11 44.5 0.1 3e-11 43.4 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EEB05269.1 - 9e-07 29.4 0.4 4.6e-06 27.1 0.2 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEB05269.1 - 6.1e-05 23.0 0.0 0.00016 21.7 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EEB05269.1 - 0.00049 20.4 0.5 0.013 15.7 0.1 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EEB05269.1 - 0.0008 19.8 0.3 0.006 17.0 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EEB05269.1 - 0.0011 18.8 1.1 0.0019 18.0 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Bac_DnaA PF00308.18 EEB05269.1 - 0.016 15.0 0.4 2 8.2 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 EEB05269.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rep_fac_C PF08542.11 EEB05269.1 - 0.024 15.1 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain Nterm_IS4 PF13006.7 EEB05269.1 - 0.036 14.3 0.0 0.28 11.4 0.0 2.3 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal AAA_24 PF13479.6 EEB05269.1 - 0.039 13.7 0.4 0.21 11.3 0.3 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EEB05269.1 - 0.091 13.3 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 EEB05269.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4979 PF16351.5 EEB05270.2 - 0.14 12.4 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4979) Mito_carr PF00153.27 EEB05271.2 - 7e-28 96.4 2.7 2e-11 43.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 EEB05272.1 - 6.4e-58 196.4 14.6 8e-58 196.1 14.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EEB05272.1 - 1.3e-11 44.8 26.7 1.1e-06 28.9 8.0 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EEB05272.1 - 3.2e-05 23.3 17.3 0.00044 19.6 17.3 2.1 1 1 0 1 1 1 1 UAA transporter family DUF2012 PF09430.10 EEB05273.1 - 2.9e-22 79.1 0.1 4.1e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 EEB05273.1 - 0.024 14.4 0.0 0.064 13.1 0.0 1.7 1 1 1 2 2 2 0 Polysaccharide lyase family 4, domain II CarbopepD_reg_2 PF13715.6 EEB05273.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 EEB05273.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain GYF PF02213.16 EEB05274.1 - 9.5e-08 31.6 3.4 2.3e-07 30.4 3.4 1.6 1 0 0 1 1 1 1 GYF domain Mucin-like PF16058.5 EEB05274.1 - 0.026 14.6 4.6 0.31 11.1 0.0 3.3 2 1 0 2 2 2 0 Mucin-like Caudo_TAP PF02413.17 EEB05274.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.6 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK CPT PF07931.12 EEB05274.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FH2 PF02181.23 EEB05275.1 - 3.8e-79 266.5 1.4 3.8e-79 266.5 1.4 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EEB05275.1 - 1.3e-21 77.2 2.5 2.3e-20 73.1 0.3 2.8 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EEB05275.1 - 4e-12 46.1 0.1 4e-12 46.1 0.1 3.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain DUF4162 PF13732.6 EEB05275.1 - 0.35 11.6 3.8 2.1 9.1 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) SlyX PF04102.12 EEB05275.1 - 0.39 11.4 5.4 7.4 7.3 2.6 4.0 2 0 0 2 2 2 0 SlyX DUF2533 PF10752.9 EEB05275.1 - 2.8 8.4 5.2 7.9 7.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) SIL1 PF16782.5 EEB05275.1 - 8.7 5.5 19.6 0.64 9.2 8.1 3.4 3 1 0 3 3 3 0 Nucleotide exchange factor SIL1 Mso1_Sec1_bdg PF14475.6 EEB05276.1 - 4.1e-07 29.5 0.3 7.7e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 zf-RAG1 PF10426.9 EEB05276.1 - 0.21 11.7 0.2 0.41 10.8 0.2 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain 2-Hacid_dh_C PF02826.19 EEB05277.1 - 2e-52 177.1 0.0 3.1e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEB05277.1 - 2.4e-07 30.5 0.0 3.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEB05277.1 - 5.3e-06 26.7 0.0 8.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEB05277.1 - 0.0022 17.6 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 EEB05277.1 - 0.026 14.6 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 EEB05277.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain SOR_SNZ PF01680.17 EEB05278.1 - 3.5e-112 373.2 4.7 4.6e-112 372.8 4.7 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EEB05278.1 - 1.4e-07 31.1 3.8 6.4e-06 25.7 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EEB05278.1 - 8e-06 25.2 0.1 0.08 12.0 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EEB05278.1 - 0.0057 16.1 0.1 0.55 9.6 0.0 2.9 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.15 EEB05278.1 - 0.0092 15.4 2.2 0.25 10.7 0.1 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase NanE PF04131.14 EEB05278.1 - 0.013 14.7 0.4 0.4 9.9 0.0 2.6 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EEB05278.1 - 0.015 14.9 0.0 5.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 EEB05278.1 - 0.053 12.9 0.2 1.9 7.8 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase TetR_C_27 PF17935.1 EEB05278.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EEB05278.1 - 0.093 11.9 0.1 4.6 6.3 0.0 2.8 2 2 1 3 3 3 0 Indole-3-glycerol phosphate synthase Sec16_C PF12931.7 EEB05279.2 - 1e-78 265.1 1.3 1.5e-78 264.5 1.3 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EEB05279.2 - 2.1e-11 44.4 0.0 1.5e-10 41.7 0.0 2.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 EEB05279.2 - 0.0013 17.9 0.5 0.0013 17.9 0.5 1.7 2 0 0 2 2 2 1 Nuclear protein 96 Rcd1 PF04078.13 EEB05280.1 - 1.1e-123 411.6 1.6 1.3e-123 411.4 1.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like MTS PF05175.14 EEB05281.1 - 2.7e-10 40.1 0.0 4.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EEB05281.1 - 1.2e-08 35.6 0.2 2.5e-08 34.5 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB05281.1 - 1e-06 28.7 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEB05281.1 - 0.00046 19.6 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EEB05281.1 - 0.00068 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB05281.1 - 0.00099 18.6 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EEB05281.1 - 0.002 18.7 0.4 0.0051 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEB05281.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 EEB05281.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Cons_hypoth95 PF03602.15 EEB05281.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EEB05281.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.12 EEB05281.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase PrmC_N PF17827.1 EEB05281.1 - 0.038 14.6 0.1 0.087 13.4 0.1 1.7 1 1 0 1 1 1 0 PrmC N-terminal domain Methyltransf_12 PF08242.12 EEB05281.1 - 0.12 13.1 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 EEB05282.1 - 1.4e-54 186.0 0.0 1.6e-54 185.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEB05282.1 - 6.9e-05 23.0 0.1 0.00015 21.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEB05282.1 - 0.0006 19.1 0.1 0.018 14.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB05282.1 - 0.0023 17.9 0.1 0.016 15.2 0.0 2.4 1 1 1 2 2 2 1 FAD-NAD(P)-binding RAG1_imp_bd PF12560.8 EEB05282.1 - 0.038 13.5 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 RAG1 importin binding Trp_halogenase PF04820.14 EEB05282.1 - 0.048 12.5 0.1 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EEB05282.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EEB05282.1 - 0.11 13.1 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEB05282.1 - 0.17 10.9 0.2 3.7 6.5 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thioredoxin PF00085.20 EEB05283.1 - 1.2e-62 208.3 2.2 5.4e-31 106.6 0.1 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EEB05283.1 - 2e-42 145.2 4.0 2.1e-26 93.0 2.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain AhpC-TSA PF00578.21 EEB05283.1 - 1.1e-11 44.8 2.5 0.00023 21.1 0.0 4.3 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EEB05283.1 - 1.6e-11 44.4 1.0 0.00023 21.4 0.0 4.6 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EEB05283.1 - 4.7e-11 43.1 5.4 9.6e-05 22.8 0.1 4.2 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EEB05283.1 - 4.3e-09 36.4 1.2 0.0035 17.5 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 EEB05283.1 - 7.8e-08 32.2 1.7 0.02 14.6 0.0 3.6 3 0 0 3 3 3 2 Redoxin OST3_OST6 PF04756.13 EEB05283.1 - 8.9e-06 25.3 0.2 0.1 11.9 0.0 3.1 2 2 0 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 EEB05283.1 - 0.00023 21.1 8.9 0.0013 18.6 0.0 4.3 4 1 0 5 5 5 1 F plasmid transfer operon protein ERp29_N PF07912.13 EEB05283.1 - 0.0026 17.9 0.3 0.099 12.8 0.0 3.3 3 1 1 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 EEB05283.1 - 0.0029 17.8 7.3 0.42 10.7 2.1 4.0 3 2 1 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.6 EEB05283.1 - 0.006 16.6 3.3 0.091 12.8 0.1 2.8 3 0 0 3 3 2 1 Thioredoxin domain DUF3986 PF13143.6 EEB05283.1 - 0.073 14.1 0.1 0.18 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) Glutaredoxin PF00462.24 EEB05283.1 - 0.074 13.3 2.9 13 6.1 1.0 3.5 2 1 0 2 2 2 0 Glutaredoxin DUF3384 PF11864.8 EEB05284.1 - 2.1e-75 254.5 7.0 3.7e-75 253.7 7.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) RIH_assoc PF08454.11 EEB05284.1 - 0.0066 16.3 0.4 0.045 13.6 0.1 2.7 2 0 0 2 2 2 1 RyR and IP3R Homology associated WD40 PF00400.32 EEB05285.1 - 8.5e-66 216.3 5.1 6.3e-09 36.3 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EEB05285.1 - 9e-27 93.2 10.4 1.4e-26 92.6 10.4 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EEB05285.1 - 4e-24 84.7 0.1 5.2e-05 23.5 0.0 6.1 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEB05285.1 - 6.2e-12 45.4 0.0 0.0011 18.4 0.0 4.7 2 1 3 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 EEB05285.1 - 6.2e-10 38.5 0.1 0.95 8.3 0.0 5.7 2 2 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEB05285.1 - 4.9e-09 36.3 0.1 0.0016 18.3 0.0 3.7 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEB05285.1 - 2.1e-08 33.9 0.1 1.5 8.9 0.0 6.2 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EEB05285.1 - 2e-06 26.7 0.4 0.29 9.7 0.0 4.9 3 2 1 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EEB05285.1 - 0.0001 20.9 0.6 0.0014 17.3 0.1 2.5 1 1 0 2 2 2 1 Cytochrome D1 heme domain nos_propeller PF18764.1 EEB05285.1 - 0.0023 17.8 0.3 6.3 6.8 0.0 4.9 4 1 2 6 6 5 1 Nitrous oxide reductase propeller repeat Vps16_N PF04841.13 EEB05285.1 - 0.0029 16.4 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region SHE3 PF17078.5 EEB05285.1 - 0.0066 16.2 7.4 0.011 15.4 7.4 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 PQQ_2 PF13360.6 EEB05285.1 - 0.0098 15.5 0.1 4.6 6.8 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain Proteasome_A_N PF10584.9 EEB05285.1 - 0.011 15.3 0.9 2.8 7.7 0.0 4.1 5 0 0 5 5 4 0 Proteasome subunit A N-terminal signature Spc7 PF08317.11 EEB05285.1 - 0.021 13.7 7.7 0.033 13.1 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein VID27 PF08553.10 EEB05285.1 - 0.038 13.0 0.1 0.83 8.6 0.0 2.8 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain VPS38 PF17649.1 EEB05285.1 - 0.08 11.8 5.0 0.11 11.3 5.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 PLC-beta_C PF08703.10 EEB05285.1 - 0.13 12.2 8.2 0.2 11.6 8.2 1.2 1 0 0 1 1 1 0 PLC-beta C terminal Prefoldin_2 PF01920.20 EEB05285.1 - 0.25 11.3 8.6 1 9.3 8.6 2.0 1 1 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.9 EEB05285.1 - 0.44 9.6 5.1 0.69 8.9 5.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKA2 PF16740.5 EEB05285.1 - 0.85 9.4 7.0 1.3 8.9 6.0 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 EEB05285.1 - 1.8 7.8 7.4 3.7 6.8 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EEB05285.1 - 2.3 8.0 7.9 3.9 7.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSNAXIP1_N PF15739.5 EEB05285.1 - 3.6 8.0 9.3 15 6.0 9.3 2.1 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus KIP1 PF07765.12 EEB05285.1 - 4.2 7.6 7.9 7.1 6.8 4.5 2.3 1 1 1 2 2 2 0 KIP1-like protein TMPIT PF07851.13 EEB05285.1 - 4.6 6.4 6.8 6.9 5.8 6.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EEB05285.1 - 5.3 5.5 7.4 7.8 5.0 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UQ_con PF00179.26 EEB05287.1 - 5.1e-51 172.0 0.1 5.7e-51 171.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEB05287.1 - 0.00033 20.4 0.0 0.00038 20.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEB05287.1 - 0.057 13.7 0.0 0.064 13.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Sas10_Utp3 PF04000.15 EEB05288.1 - 2.5e-10 40.8 0.5 2.5e-10 40.8 0.5 2.5 3 1 0 3 3 3 1 Sas10/Utp3/C1D family CEP63 PF17045.5 EEB05288.1 - 0.06 13.3 9.3 0.21 11.5 0.3 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa Mannosyl_trans2 PF04188.13 EEB05289.1 - 3.1e-46 158.6 28.7 4.3e-39 135.1 19.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) EF-hand_7 PF13499.6 EEB05290.1 - 3.1e-25 88.4 5.7 4.1e-16 59.2 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EEB05290.1 - 5.9e-25 84.9 9.0 3e-07 29.5 0.2 5.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EEB05290.1 - 3.5e-23 79.5 5.6 1e-06 28.2 0.1 5.5 4 1 2 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 EEB05290.1 - 4.9e-16 57.4 7.1 6.4e-06 25.4 0.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EEB05290.1 - 5.3e-12 45.4 9.2 0.00028 20.7 0.5 4.0 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EEB05290.1 - 4.1e-07 29.9 7.2 0.25 11.3 0.1 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EEB05290.1 - 0.00022 21.5 1.8 0.78 10.1 0.2 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EEB05290.1 - 0.00083 19.6 0.2 0.065 13.6 0.1 3.3 2 1 0 3 3 3 1 EF-hand domain S10_plectin PF03501.15 EEB05290.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain Pan3_PK PF18101.1 EEB05290.1 - 0.039 13.9 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Caleosin PF05042.13 EEB05290.1 - 0.32 10.9 3.0 17 5.3 0.0 3.5 2 1 1 4 4 4 0 Caleosin related protein Med4 PF10018.9 EEB05291.1 - 1.8e-13 50.6 1.5 2.7e-13 50.1 1.0 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TACC_C PF05010.14 EEB05291.1 - 0.36 10.6 8.1 0.22 11.3 2.9 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PCI PF01399.27 EEB05292.1 - 4.8e-12 46.3 0.0 2.6e-11 43.9 0.0 2.3 3 0 0 3 3 3 1 PCI domain EMP70 PF02990.16 EEB05293.1 - 5.3e-172 573.1 15.2 6e-172 572.9 15.2 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 PsaL PF02605.15 EEB05293.1 - 0.27 10.9 1.6 0.84 9.3 0.0 2.5 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI UQ_con PF00179.26 EEB05294.2 - 1.8e-36 124.8 0.1 2.2e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rav1p_C PF12234.8 EEB05295.1 - 5.7e-218 725.4 0.2 8.7e-218 724.8 0.2 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal HPS3_N PF14761.6 EEB05295.1 - 0.0085 15.7 0.0 0.064 12.8 0.0 2.3 1 1 1 2 2 2 1 Hermansky-Pudlak syndrome 3 WD40 PF00400.32 EEB05295.1 - 0.01 16.6 9.9 95 4.1 0.2 6.6 5 1 1 6 6 6 0 WD domain, G-beta repeat Histone PF00125.24 EEB05296.1 - 1.2e-51 174.5 1.1 1.3e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEB05296.1 - 7.3e-06 26.3 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEB05296.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEB05296.1 - 0.00068 20.2 2.4 0.00087 19.9 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEB05296.1 - 0.0086 16.3 0.2 0.016 15.5 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EEB05297.1 - 6.7e-09 35.8 0.1 8.2e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EEB05297.1 - 4e-06 27.0 0.1 6.9e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB05297.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EEB05297.1 - 1.6e-05 25.0 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EEB05297.1 - 0.0001 22.6 0.1 0.00013 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEB05297.1 - 0.0065 16.5 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEB05297.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EEB05297.1 - 0.16 12.5 0.1 0.25 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A zf-C2H2 PF00096.26 EEB05298.1 - 8.3e-10 38.6 5.7 5.3e-05 23.5 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB05298.1 - 4.8e-07 30.1 3.5 0.0033 18.1 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EEB05298.1 - 0.0012 19.1 1.5 0.0021 18.3 1.5 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EEB05298.1 - 0.02 15.3 3.0 0.8 10.2 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf_ZIC PF18366.1 EEB05298.1 - 0.14 12.3 0.2 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 EEB05298.1 - 0.2 11.7 0.6 1.9 8.6 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEB05298.1 - 0.83 9.5 2.2 0.68 9.7 0.5 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Rpr2 PF04032.16 EEB05300.1 - 3e-21 75.5 1.1 4.5e-21 74.9 1.1 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_16 PF17034.5 EEB05300.1 - 0.05 13.8 1.9 3 8.1 0.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon like family ADD_ATRX PF17981.1 EEB05300.1 - 0.085 12.7 1.9 0.18 11.7 0.5 2.1 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-RRN7 PF11781.8 EEB05300.1 - 0.68 9.7 4.3 3.8 7.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 EEB05300.1 - 0.69 9.9 4.7 6 6.9 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Histone PF00125.24 EEB05301.1 - 3.7e-42 143.8 0.1 4.2e-42 143.6 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EEB05301.1 - 0.00038 20.5 0.0 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EEB05301.1 - 0.0012 19.2 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EEB05301.1 - 0.0084 16.4 1.3 0.023 15.0 1.3 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RF-1 PF00472.20 EEB05302.1 - 3.7e-22 78.5 1.8 4.6e-22 78.1 1.8 1.1 1 0 0 1 1 1 1 RF-1 domain ARD PF03079.14 EEB05303.1 - 4.2e-44 150.5 0.2 5e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EEB05303.1 - 9.9e-08 31.6 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_8 PF13621.6 EEB05303.1 - 0.0059 16.3 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 EEB05303.1 - 0.062 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 EEB05303.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_76 PF03663.14 EEB05304.1 - 2.4e-126 422.2 16.5 2.8e-126 421.9 16.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PQ-loop PF04193.14 EEB05304.1 - 0.083 12.7 0.9 0.38 10.6 0.7 2.0 2 0 0 2 2 2 0 PQ loop repeat NOC3p PF07540.11 EEB05305.2 - 5.5e-28 97.3 0.2 4e-27 94.5 0.2 2.7 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EEB05305.2 - 3.5e-15 56.5 0.1 3.5e-15 56.5 0.1 3.3 3 1 0 3 3 3 1 CBF/Mak21 family PFU PF09070.11 EEB05306.2 - 6.7e-45 152.0 0.4 1.9e-44 150.6 0.4 1.8 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 EEB05306.2 - 2.6e-36 125.3 0.1 4.7e-36 124.5 0.0 1.5 2 0 0 2 2 2 1 PUL domain WD40 PF00400.32 EEB05306.2 - 6.6e-29 99.6 22.8 7.2e-07 29.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 EEB05306.2 - 5.1e-09 36.1 0.0 0.068 13.2 0.0 4.9 2 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EEB05306.2 - 0.0002 20.8 0.0 0.0042 16.5 0.0 2.8 1 1 2 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 EEB05306.2 - 0.00025 21.3 0.8 2.5 8.4 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EEB05307.1 - 2.2e-17 62.6 0.0 4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB05307.1 - 0.005 16.4 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB05307.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Zip PF02535.22 EEB05307.1 - 9.8 5.3 7.8 14 4.8 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PX PF00787.24 EEB05308.1 - 2.6e-29 101.5 0.5 3.1e-29 101.2 0.5 1.1 1 0 0 1 1 1 1 PX domain NAD_binding_9 PF13454.6 EEB05308.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Ribosomal_L14 PF00238.19 EEB05309.1 - 1.3e-43 148.0 0.7 1.4e-43 147.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_2 PF07719.17 EEB05310.1 - 0.023 14.8 1.2 0.057 13.6 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05310.1 - 0.04 13.7 1.1 0.08 12.8 1.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SOG2 PF10428.9 EEB05311.1 - 5.7e-51 174.3 11.3 1e-34 120.6 0.4 4.2 2 2 2 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 EEB05311.1 - 1e-14 54.0 18.0 1.7e-07 30.9 2.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EEB05311.1 - 2.6e-11 43.6 8.6 1.2e-05 25.5 0.2 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEB05311.1 - 0.0032 17.8 6.4 20 6.2 0.1 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EEB05311.1 - 0.46 10.7 8.3 18 5.7 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Response_reg PF00072.24 EEB05312.2 - 1.3e-21 76.9 0.1 1.7e-15 57.1 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain PseudoU_synth_1 PF01416.20 EEB05313.1 - 4.1e-13 49.7 0.0 1.4e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EEB05313.1 - 0.0074 16.1 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2344) DUF5473 PF17567.2 EEB05314.1 - 0.0034 17.6 3.8 0.0057 16.9 3.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5473) PI-PLC-X PF00388.19 EEB05315.2 - 7.3e-59 197.5 0.0 1.9e-58 196.2 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EEB05315.2 - 3.2e-35 120.9 0.0 7.6e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EEB05315.2 - 6.1e-08 33.0 1.5 1.6e-07 31.7 0.3 2.3 1 1 2 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 EEB05315.2 - 3.5e-07 30.5 0.0 7.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EEB05315.2 - 0.0029 18.0 0.2 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair PH_12 PF16457.5 EEB05315.2 - 0.023 15.3 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_6 PF13405.6 EEB05315.2 - 0.023 14.6 0.3 0.29 11.2 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EEB05315.2 - 0.078 12.8 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 EEB05315.2 - 0.1 12.2 0.0 0.32 10.6 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF382 PF04037.13 EEB05316.1 - 8.8e-59 197.2 0.2 8.8e-59 197.2 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EEB05316.1 - 2e-22 78.8 0.9 4e-22 77.8 0.9 1.5 1 0 0 1 1 1 1 PSP ING PF12998.7 EEB05316.1 - 2.1 9.0 7.2 4.8 7.8 1.4 2.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Nop53 PF07767.11 EEB05317.1 - 3.8e-99 332.8 34.7 3.8e-99 332.8 34.7 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 EEB05317.1 - 0.019 13.3 12.1 0.031 12.6 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein TMPIT PF07851.13 EEB05317.1 - 2.4 7.3 8.4 5.2 6.2 8.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein Nuc_deoxyri_tr2 PF15891.5 EEB05317.1 - 3.9 7.8 5.8 0.86 9.9 0.3 2.6 1 1 2 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like Presenilin PF01080.17 EEB05317.1 - 4.3 6.0 10.8 6.3 5.5 10.8 1.2 1 0 0 1 1 1 0 Presenilin DUF3461 PF11944.8 EEB05318.1 - 0.048 13.8 13.5 0.057 13.5 2.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) PAS_10 PF13596.6 EEB05318.1 - 0.59 10.8 2.3 1.1 9.9 0.1 2.6 3 0 0 3 3 3 0 PAS domain Baculo_PEP_C PF04513.12 EEB05318.1 - 1.1 9.3 10.0 0.54 10.3 1.0 3.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltr_RsmB-F PF01189.17 EEB05319.2 - 5.7e-38 130.6 0.0 1.2e-36 126.2 0.0 2.8 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EEB05319.2 - 0.0089 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.32 EEB05320.1 - 1e-14 54.6 11.9 0.00023 21.9 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EEB05320.1 - 0.014 14.4 0.0 0.52 9.2 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC45 PF02724.14 EEB05321.2 - 2.3e-223 743.1 5.7 2.6e-223 742.9 5.7 1.0 1 0 0 1 1 1 1 CDC45-like protein Cation_efflux PF01545.21 EEB05322.1 - 6e-47 160.0 1.9 6e-47 160.0 1.9 2.4 3 0 0 3 3 3 1 Cation efflux family Stk19 PF10494.9 EEB05323.1 - 2.9e-34 118.9 0.0 3.9e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NAGLU_C PF12972.7 EEB05323.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain TRAPP PF04051.16 EEB05323.1 - 0.11 12.2 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component AAA PF00004.29 EEB05324.1 - 2.4e-53 180.1 0.0 2.6e-40 137.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 EEB05324.1 - 2.6e-12 46.3 0.0 2.8e-09 36.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 EEB05324.1 - 2.1e-09 37.1 0.1 4.7e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EEB05324.1 - 3.5e-08 33.8 0.2 0.00083 19.6 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EEB05324.1 - 2.2e-07 31.4 0.1 0.007 16.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EEB05324.1 - 7.5e-07 29.4 0.0 1e-05 25.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EEB05324.1 - 9.9e-06 25.0 0.1 0.071 12.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain ATPase_2 PF01637.18 EEB05324.1 - 9.9e-06 25.6 0.1 2 8.2 0.0 4.3 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea CDC48_N PF02359.18 EEB05324.1 - 5.2e-05 23.3 0.0 0.00047 20.3 0.0 2.6 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 EEB05324.1 - 7.7e-05 22.2 0.1 0.0044 16.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EEB05324.1 - 9.5e-05 22.2 0.0 0.037 13.8 0.0 3.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEB05324.1 - 0.00011 22.2 0.0 0.0014 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EEB05324.1 - 0.00013 22.0 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEB05324.1 - 0.00013 22.5 0.1 0.11 13.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 EEB05324.1 - 0.00019 21.4 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EEB05324.1 - 0.0016 18.0 0.1 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EEB05324.1 - 0.0022 18.3 0.0 0.24 11.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 EEB05324.1 - 0.004 16.9 0.0 0.055 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEB05324.1 - 0.0059 16.4 0.1 0.3 10.8 0.0 2.6 3 0 0 3 3 2 1 IstB-like ATP binding protein TniB PF05621.11 EEB05324.1 - 0.0069 15.8 0.2 2.3 7.6 0.0 3.5 3 1 0 3 3 3 1 Bacterial TniB protein AAA_33 PF13671.6 EEB05324.1 - 0.007 16.5 0.0 0.34 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEB05324.1 - 0.0071 16.3 0.2 5.1 7.0 0.0 4.0 4 1 0 4 4 4 0 NACHT domain ATPase PF06745.13 EEB05324.1 - 0.01 15.2 0.9 0.037 13.4 0.1 2.2 2 1 1 3 3 3 0 KaiC ABC_tran PF00005.27 EEB05324.1 - 0.013 16.0 0.8 0.041 14.4 0.1 2.2 2 0 0 2 2 1 0 ABC transporter T2SSE PF00437.20 EEB05324.1 - 0.02 13.9 0.1 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EEB05324.1 - 0.024 14.4 0.1 0.91 9.2 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EEB05324.1 - 0.034 14.4 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EEB05324.1 - 0.054 12.7 0.1 1.2 8.3 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Parvo_NS1 PF01057.17 EEB05324.1 - 0.055 12.6 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 EEB05324.1 - 0.058 13.2 0.3 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EEB05324.1 - 0.089 12.5 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EEB05324.1 - 0.093 12.2 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 EEB05324.1 - 0.096 13.0 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB05324.1 - 0.12 11.9 5.1 3.8 7.0 0.1 4.0 4 0 0 4 4 4 0 AAA domain Vps4_C PF09336.10 EEB05324.1 - 0.12 12.3 0.0 0.58 10.2 0.0 2.2 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_11 PF13086.6 EEB05324.1 - 0.18 11.6 0.0 0.48 10.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain HATPase_c PF02518.26 EEB05325.1 - 2.6e-22 79.4 0.0 5.2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEB05325.1 - 2.7e-21 75.8 0.0 1e-20 74.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 EEB05325.1 - 5.6e-18 65.0 0.0 2.7e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 EEB05325.1 - 2.3e-17 62.8 0.1 6.3e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EEB05325.1 - 1.9e-13 50.4 0.0 7.4e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EEB05325.1 - 7.6e-13 48.6 0.0 6e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EEB05325.1 - 1.5e-12 47.7 0.0 2.7e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EEB05325.1 - 5.8e-10 39.0 0.0 0.00077 19.4 0.0 2.9 3 0 0 3 3 3 2 PAS domain Kinesin PF00225.23 EEB05326.1 - 3.4e-109 364.8 0.1 4.4e-109 364.4 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEB05326.1 - 1.1e-27 96.8 0.1 3.6e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Mo25 PF08569.11 EEB05327.1 - 8.8e-122 406.5 6.0 1e-121 406.4 6.0 1.0 1 0 0 1 1 1 1 Mo25-like Glyco_transf_22 PF03901.17 EEB05328.1 - 1.9e-99 333.7 27.6 2.4e-99 333.4 27.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Histone PF00125.24 EEB05329.1 - 1.2e-51 174.5 1.1 1.3e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEB05329.1 - 7.3e-06 26.3 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEB05329.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEB05329.1 - 0.00068 20.2 2.4 0.00087 19.9 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEB05329.1 - 0.0086 16.3 0.2 0.016 15.5 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EEB05330.1 - 6.7e-09 35.8 0.1 8.2e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EEB05330.1 - 4e-06 27.0 0.1 6.9e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB05330.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EEB05330.1 - 1.6e-05 25.0 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EEB05330.1 - 0.0001 22.6 0.1 0.00013 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEB05330.1 - 0.0065 16.5 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEB05330.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EEB05330.1 - 0.16 12.5 0.1 0.25 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A EPSP_synthase PF00275.20 EEB05331.1 - 2.6e-128 428.3 0.0 4.1e-128 427.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EEB05331.1 - 3.4e-98 328.0 0.0 6.2e-98 327.1 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EEB05331.1 - 2e-53 182.0 0.0 4.6e-53 180.8 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EEB05331.1 - 2.2e-35 122.1 0.1 1.8e-34 119.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EEB05331.1 - 2.4e-25 88.6 0.0 5.9e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EEB05331.1 - 3e-09 36.9 0.0 3.4e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EEB05331.1 - 9.5e-07 28.5 0.2 9.5e-07 28.5 0.2 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EEB05331.1 - 1.4e-06 28.4 0.1 3.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 EEB05331.1 - 3.2e-05 24.1 0.0 0.073 13.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EEB05331.1 - 0.0093 16.0 0.0 0.068 13.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EEB05331.1 - 0.03 14.7 0.0 0.096 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EEB05331.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EEB05331.1 - 0.075 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 EEB05331.1 - 0.13 12.5 0.1 2.3 8.5 0.1 3.0 2 1 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain AAA_24 PF13479.6 EEB05331.1 - 0.14 11.8 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEB05331.1 - 0.16 12.4 0.0 4.5 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain eRF1_2 PF03464.15 EEB05332.1 - 3.5e-47 160.1 0.1 5.2e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EEB05332.1 - 4.4e-38 130.2 0.2 9.2e-38 129.2 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EEB05332.1 - 2.4e-19 69.6 0.0 4.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EEB05332.1 - 1.8e-11 44.4 0.4 3.3e-11 43.6 0.4 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EEB05332.1 - 5.9e-11 42.8 0.9 8.8e-11 42.2 0.9 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor COQ9 PF08511.11 EEB05332.1 - 0.14 12.0 0.1 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 COQ9 EamA PF00892.20 EEB05333.1 - 1.4e-05 25.3 32.7 0.0006 20.0 11.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family Recep_L_domain PF01030.24 EEB05334.1 - 1.7e-10 41.0 2.4 0.0077 16.3 0.0 4.0 2 2 2 4 4 4 4 Receptor L domain LRR_5 PF13306.6 EEB05334.1 - 0.00039 20.4 1.8 0.0047 16.9 0.1 2.9 1 1 2 3 3 3 1 BspA type Leucine rich repeat region (6 copies) RWP-RK PF02042.15 EEB05334.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain DUF2807 PF10988.8 EEB05334.1 - 0.2 11.5 14.1 0.019 14.7 7.0 2.6 3 0 0 3 3 3 0 Putative auto-transporter adhesin, head GIN domain zf-rbx1 PF12678.7 EEB05335.1 - 2.8e-25 88.3 11.9 4e-25 87.8 11.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEB05335.1 - 2.9e-18 65.7 9.3 3.8e-18 65.3 9.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EEB05335.1 - 1.8e-06 28.2 14.4 7.1e-05 23.1 14.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB05335.1 - 6.1e-06 26.0 2.1 6.1e-06 26.0 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB05335.1 - 0.00028 20.7 11.4 0.0018 18.1 11.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEB05335.1 - 0.0014 18.3 2.0 0.0014 18.3 2.0 2.4 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EEB05335.1 - 0.052 13.4 9.4 0.19 11.6 3.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB05335.1 - 0.21 11.7 7.6 0.78 9.8 7.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EEB05335.1 - 0.25 11.0 14.6 42 3.9 14.6 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EEB05335.1 - 0.39 10.9 8.6 2.1 8.6 8.8 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EEB05335.1 - 1.6 8.7 11.3 9.3 6.3 11.3 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 EEB05336.2 - 3e-64 216.9 0.0 3.6e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05336.2 - 7e-33 114.0 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05336.2 - 0.001 18.5 0.0 0.0024 17.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEB05336.2 - 0.03 13.3 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CNOT11 PF10155.9 EEB05337.1 - 0.00092 19.4 4.4 0.0024 18.0 3.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 RIBIOP_C PF04950.12 EEB05338.1 - 1.5e-109 365.9 2.0 2.2e-109 365.4 0.1 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEB05338.1 - 5.1e-19 68.2 0.2 4.4e-18 65.2 0.2 2.4 1 1 0 1 1 1 1 AARP2CN (NUC121) domain ParE-like_toxin PF15781.5 EEB05338.1 - 0.16 11.9 0.3 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 ParE-like toxin of type II bacterial toxin-antitoxin system DUF2383 PF09537.10 EEB05338.1 - 1.2 9.5 5.6 0.77 10.1 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Vps39_1 PF10366.9 EEB05339.2 - 1.6e-26 92.7 6.2 2.3e-24 85.8 0.0 3.7 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EEB05339.2 - 2.3e-24 86.0 3.4 2.9e-24 85.6 0.1 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EEB05339.2 - 6.4e-10 39.1 0.2 2.5e-09 37.2 0.1 2.0 1 1 1 2 2 2 1 CNH domain Clathrin PF00637.20 EEB05339.2 - 7.3e-10 38.9 10.6 1.8e-08 34.3 5.7 3.2 2 1 0 2 2 2 2 Region in Clathrin and VPS TPR_19 PF14559.6 EEB05339.2 - 0.3 11.6 1.4 1.6 9.3 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4050 PF13259.6 EEB05340.1 - 0.0016 18.8 7.7 0.098 13.0 0.1 2.9 2 1 1 3 3 3 3 Protein of unknown function (DUF4050) T2SSM PF04612.12 EEB05341.1 - 0.0018 18.4 1.2 0.0024 18.0 1.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Spc7 PF08317.11 EEB05341.1 - 0.0024 16.8 1.7 0.0031 16.4 1.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GHL5 PF14872.6 EEB05341.1 - 0.026 12.6 0.4 0.033 12.2 0.4 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Nup54 PF13874.6 EEB05341.1 - 0.059 13.5 3.2 0.078 13.1 3.2 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 NAPRTase_C PF17956.1 EEB05341.1 - 0.12 12.8 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain HNH_repeat PF18780.1 EEB05341.1 - 0.19 11.5 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Homing endonuclease repeat KxDL PF10241.9 EEB05341.1 - 0.34 11.2 4.0 0.63 10.4 4.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein MRG PF05712.13 EEB05342.2 - 2.8e-43 147.6 0.6 4.6e-43 146.9 0.6 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EEB05342.2 - 2.4e-11 43.3 0.3 4.6e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain CLTH PF10607.9 EEB05342.2 - 0.042 13.7 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Chromo PF00385.24 EEB05342.2 - 0.2 11.6 5.3 0.46 10.4 5.3 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 EEB05343.1 - 1e-18 67.2 1.1 2.3e-18 66.1 0.1 2.2 2 0 0 2 2 2 1 Cnl2/NKP2 family protein COG2 PF06148.11 EEB05343.1 - 0.039 14.0 0.8 0.039 14.0 0.8 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Glutaredoxin2_C PF04399.13 EEB05343.1 - 0.059 13.2 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain dCMP_cyt_deam_1 PF00383.23 EEB05345.1 - 7.6e-10 38.6 0.1 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEB05345.1 - 0.0012 18.6 0.5 0.0049 16.6 0.5 1.9 1 1 0 1 1 1 1 MafB19-like deaminase D123 PF07065.14 EEB05346.2 - 4.7e-90 301.9 0.1 5.8e-90 301.6 0.1 1.1 1 0 0 1 1 1 1 D123 DUF2805 PF10985.8 EEB05346.2 - 0.14 12.6 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) R2K_3 PF14243.6 EEB05346.2 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 TPR_12 PF13424.6 EEB05347.1 - 1.8e-14 53.8 3.7 0.00023 21.4 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05347.1 - 6.1e-14 50.9 6.7 0.00042 20.2 0.4 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05347.1 - 3.7e-11 42.9 0.7 0.057 14.3 0.3 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05347.1 - 2.1e-10 39.9 9.9 0.011 15.6 0.2 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05347.1 - 1.7e-09 37.1 9.1 0.022 14.9 0.2 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEB05347.1 - 2.5e-09 36.5 0.6 1.5 9.0 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05347.1 - 7.5e-09 36.1 1.9 0.16 12.7 0.2 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05347.1 - 9.3e-06 26.1 6.0 0.018 15.6 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 EEB05347.1 - 5.3e-05 23.0 0.7 2.7 7.7 0.0 3.8 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 EEB05347.1 - 0.0029 17.4 9.4 1.9 8.5 0.2 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EEB05347.1 - 0.0042 17.1 1.1 3.4 7.8 0.1 3.3 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 EEB05347.1 - 0.0048 16.6 2.3 0.63 9.7 0.2 2.4 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 EEB05347.1 - 0.014 16.0 5.0 15 6.5 0.4 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat 14-3-3 PF00244.20 EEB05347.1 - 0.021 14.4 0.4 0.021 14.4 0.4 2.0 2 0 0 2 2 2 0 14-3-3 protein TPR_11 PF13414.6 EEB05347.1 - 0.021 14.5 4.4 24 4.7 0.0 4.7 4 1 1 5 5 5 0 TPR repeat Sel1 PF08238.12 EEB05347.1 - 0.032 14.9 0.8 14 6.5 0.1 3.5 4 0 0 4 4 3 0 Sel1 repeat ANAPC3 PF12895.7 EEB05347.1 - 0.12 12.6 3.3 5.9 7.2 0.3 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EEB05347.1 - 0.97 10.0 0.1 0.97 10.0 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 EEB05348.1 - 4.3e-103 345.0 2.5 7e-103 344.3 2.5 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EEB05348.1 - 6.2e-38 129.0 0.2 1.6e-37 127.7 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEB05348.1 - 2.3e-05 24.8 0.0 2.3e-05 24.8 0.0 2.8 3 1 0 3 3 3 1 PH domain PH_3 PF14593.6 EEB05348.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 PH domain Pkinase PF00069.25 EEB05349.2 - 5.5e-68 229.2 0.0 7e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05349.2 - 4.1e-35 121.3 0.0 5.9e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EEB05349.2 - 1.3e-08 35.3 0.0 3.1e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Haspin_kinase PF12330.8 EEB05349.2 - 1.9e-05 23.8 0.9 2.7e-05 23.3 0.9 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEB05349.2 - 0.0004 19.8 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB05349.2 - 0.0005 19.5 3.7 0.0012 18.3 3.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 EEB05350.1 - 2.7e-35 121.9 0.0 3.1e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5316 PF17247.2 EEB05350.1 - 0.031 14.3 0.1 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5316) SBD PF17882.1 EEB05350.1 - 0.15 11.9 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain tRNA_Me_trans PF03054.16 EEB05351.2 - 4.6e-110 367.7 0.0 5.3e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 EEB05351.2 - 0.033 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ThiI PF02568.14 EEB05351.2 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 EEB05351.2 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Gln-synt_C PF00120.24 EEB05352.2 - 2e-17 63.2 0.0 4.1e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EEB05352.2 - 1.4e-13 50.4 0.0 2.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SRPRB PF09439.10 EEB05353.1 - 8.3e-29 100.3 0.0 1e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EEB05353.1 - 3e-11 43.1 0.0 6.2e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEB05353.1 - 1.2e-08 35.0 0.0 3.1e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEB05353.1 - 2.1e-06 27.4 0.0 0.00061 19.4 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEB05353.1 - 7.9e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EEB05353.1 - 3.7e-05 23.3 0.0 9.3e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 EEB05353.1 - 0.0016 18.7 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EEB05353.1 - 0.0023 17.8 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Parvo_NS1 PF01057.17 EEB05353.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Dynamin_N PF00350.23 EEB05353.1 - 0.028 14.5 0.5 1.3 9.0 0.0 2.5 2 1 1 3 3 3 0 Dynamin family Ras PF00071.22 EEB05353.1 - 0.034 13.7 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Ras family DUF4596 PF15363.6 EEB05353.1 - 0.042 14.1 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) AAA_22 PF13401.6 EEB05353.1 - 0.067 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 EEB05353.1 - 0.08 11.8 0.0 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain Wbp11 PF09429.10 EEB05354.1 - 2.4e-15 56.7 13.5 2.4e-15 56.7 13.5 2.5 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.7 EEB05354.1 - 5.9e-15 55.8 9.8 1.9e-14 54.1 9.0 2.4 2 0 0 2 2 2 1 mRNA biogenesis factor PI3_PI4_kinase PF00454.27 EEB05355.1 - 2.1e-61 207.9 0.2 8.2e-61 206.0 0.2 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EEB05355.1 - 1.6e-31 109.8 3.0 4.3e-31 108.4 3.0 1.8 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EEB05355.1 - 2.1e-21 75.7 0.0 2.1e-21 75.7 0.0 3.5 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.20 EEB05355.1 - 5.3e-15 54.9 0.0 1.7e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EEB05355.1 - 0.012 15.5 0.2 0.39 10.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) SelR PF01641.18 EEB05356.2 - 9.7e-48 161.2 0.1 1.3e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.6 EEB05356.2 - 0.094 13.2 3.5 1.6 9.3 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L37e PF01907.19 EEB05356.2 - 0.59 10.3 3.1 5.6 7.2 0.6 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e NAD_binding_10 PF13460.6 EEB05357.1 - 3.7e-33 115.0 0.0 4.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEB05357.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EEB05357.1 - 2.1e-07 30.7 0.1 5.1e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 EEB05357.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Mcp5_PH PF12814.7 EEB05359.1 - 2e-35 121.5 1.1 5.5e-35 120.1 1.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF489 PF04356.12 EEB05359.1 - 0.27 11.2 4.9 0.65 10.0 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) FUSC PF04632.12 EEB05359.1 - 0.3 9.6 5.7 0.57 8.6 5.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.16 EEB05359.1 - 2.2 8.7 13.1 1.1 9.7 8.7 2.8 1 1 1 2 2 2 0 Tubulin binding cofactor A SMK-1 PF04802.15 EEB05360.1 - 7.4e-70 234.7 4.3 7.4e-70 234.7 4.3 2.5 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 Med26_C PF15693.5 EEB05360.1 - 0.14 12.3 6.6 0.35 11.0 6.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal SE PF08491.10 EEB05361.1 - 2e-113 378.0 0.1 2.7e-113 377.6 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EEB05361.1 - 2.6e-13 49.9 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEB05361.1 - 2.6e-07 30.5 0.4 0.00039 20.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EEB05361.1 - 6.8e-06 25.4 0.0 9.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EEB05361.1 - 6.6e-05 22.2 1.3 0.018 14.1 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEB05361.1 - 0.00044 20.4 0.6 0.001 19.2 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EEB05361.1 - 0.0022 17.3 1.0 0.0055 16.0 0.3 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EEB05361.1 - 0.0034 16.8 0.4 0.0044 16.4 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 EEB05361.1 - 0.0072 16.0 0.2 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EEB05361.1 - 0.012 14.9 0.2 0.021 14.1 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EEB05361.1 - 0.018 15.3 0.8 0.08 13.2 0.3 2.0 2 0 0 2 2 2 0 TrkA-N domain DNase_II PF03265.15 EEB05361.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II Pyr_redox PF00070.27 EEB05361.1 - 0.028 15.0 1.5 0.036 14.6 0.3 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 EEB05361.1 - 0.038 13.8 0.2 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Rossmann-like domain GMC_oxred_N PF00732.19 EEB05361.1 - 0.048 13.0 0.2 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase NAD_Gly3P_dh_N PF01210.23 EEB05361.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 EEB05361.1 - 0.09 11.8 0.2 0.55 9.2 0.6 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 EEB05361.1 - 0.14 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EEB05361.1 - 0.14 12.7 0.8 0.48 11.0 0.2 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GDI PF00996.18 EEB05361.1 - 0.16 10.4 0.1 0.25 9.8 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 EEB05361.1 - 0.19 10.9 0.7 0.3 10.3 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEB05361.1 - 0.24 10.1 0.3 0.33 9.6 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Pmp3 PF01679.17 EEB05362.1 - 5e-24 84.3 9.5 5.5e-24 84.1 9.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pam16 PF03656.13 EEB05363.1 - 3e-22 79.0 4.0 3.6e-22 78.7 4.0 1.0 1 0 0 1 1 1 1 Pam16 Calc_CGRP_IAPP PF00214.19 EEB05363.1 - 0.081 13.3 0.6 0.39 11.1 0.6 1.9 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF4775 PF16001.5 EEB05364.1 - 0.0026 17.3 55.4 0.0031 17.0 55.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4775) Nup188 PF10487.9 EEB05365.2 - 3.1e-103 346.4 10.3 7.2e-103 345.2 10.3 1.6 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EEB05365.2 - 9.3e-24 83.9 8.1 2.3e-23 82.7 8.1 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain GTP_cyclohydro2 PF00925.20 EEB05366.1 - 1.3e-63 213.4 0.1 1.7e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II CDC24_OB3 PF17244.2 EEB05367.1 - 0.00051 19.8 0.1 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti-codon PF01336.25 EEB05367.1 - 0.0013 18.7 0.0 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EEB05367.1 - 0.12 12.6 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Pkinase PF00069.25 EEB05368.1 - 2.7e-11 43.3 0.1 3.9e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EEB05368.1 - 7.9e-09 35.2 0.1 1.6e-08 34.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EEB05368.1 - 1.9e-07 30.7 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB05368.1 - 3.3e-06 27.2 0.2 0.00072 19.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EEB05368.1 - 3.3e-06 26.8 0.0 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 EEB05368.1 - 7.1e-05 22.3 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EEB05368.1 - 0.0037 16.9 1.0 0.028 14.0 1.0 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EEB05368.1 - 0.0074 15.1 0.0 0.0074 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase NRDE-2 PF08424.10 EEB05368.1 - 0.036 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference WaaY PF06176.11 EEB05368.1 - 0.038 13.6 0.1 0.052 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Clat_adaptor_s PF01217.20 EEB05369.1 - 1.6e-52 177.2 0.7 1.9e-52 176.9 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MRG PF05712.13 EEB05369.1 - 0.044 13.1 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 MRG Clathrin PF00637.20 EEB05370.1 - 3.6e-16 59.3 1.4 3.6e-16 59.3 1.4 3.1 3 1 1 4 4 4 1 Region in Clathrin and VPS Vps39_2 PF10367.9 EEB05370.1 - 9.3e-07 29.3 1.0 0.032 14.7 0.3 2.7 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 EEB05370.1 - 0.072 14.0 0.0 0.26 12.2 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat HK PF02110.15 EEB05371.1 - 8.1e-80 267.8 0.4 1.3e-79 267.1 0.4 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EEB05371.1 - 7e-58 194.9 3.2 1.2e-57 194.2 3.2 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EEB05371.1 - 0.036 13.5 0.3 0.15 11.5 0.1 2.0 2 0 0 2 2 2 0 Carbohydrate kinase Peptidase_M24 PF00557.24 EEB05372.1 - 6.7e-18 65.1 0.1 8.9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3850 PF12961.7 EEB05372.1 - 0.098 12.7 0.2 24 5.1 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3850) ThrE PF06738.12 EEB05372.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Iwr1 PF08574.10 EEB05373.2 - 3.2e-12 47.3 11.1 7.8e-12 46.0 11.1 1.7 1 0 0 1 1 1 1 Transcription factor Iwr1 Ribosomal_L19e PF01280.20 EEB05374.1 - 7.6e-62 207.6 10.0 7.6e-62 207.6 10.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e Actin PF00022.19 EEB05375.1 - 7.3e-18 64.4 0.2 4.8e-10 38.6 0.0 2.4 2 1 0 2 2 2 2 Actin DRIM PF07539.12 EEB05376.2 - 5e-149 497.5 9.0 5e-149 497.5 9.0 5.0 6 1 0 6 6 6 2 Down-regulated in metastasis Zn_clus PF00172.18 EEB05377.1 - 0.00077 19.5 11.6 0.0016 18.5 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LEM PF03020.15 EEB05377.1 - 0.49 10.0 0.0 0.49 10.0 0.0 1.7 2 0 0 2 2 2 0 LEM domain AAA PF00004.29 EEB05381.1 - 5.5e-90 298.6 0.0 1.8e-44 151.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB05381.1 - 5.5e-25 86.9 6.6 4e-12 45.7 0.2 2.9 2 1 1 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 EEB05381.1 - 8e-13 48.4 0.0 0.00011 22.0 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEB05381.1 - 1e-11 45.0 0.1 6.8e-05 22.9 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB05381.1 - 2.1e-10 41.3 0.5 8.5e-05 23.0 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EEB05381.1 - 7.6e-10 39.2 0.0 0.00026 21.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEB05381.1 - 4.9e-08 33.3 2.4 0.0077 16.5 0.1 4.9 3 2 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EEB05381.1 - 6e-07 29.7 0.0 0.0033 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EEB05381.1 - 1e-05 25.6 0.0 0.045 13.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EEB05381.1 - 1.2e-05 25.0 4.3 0.29 10.7 0.0 4.3 3 1 1 4 4 4 1 AAA domain Rad17 PF03215.15 EEB05381.1 - 1.2e-05 25.3 0.0 0.01 15.8 0.0 2.9 2 1 1 3 3 3 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EEB05381.1 - 5.1e-05 22.8 0.2 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EEB05381.1 - 6.4e-05 22.3 0.0 0.32 10.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 EEB05381.1 - 6.5e-05 23.2 0.2 0.23 11.7 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EEB05381.1 - 0.0001 21.9 0.0 0.17 11.4 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region TsaE PF02367.17 EEB05381.1 - 0.00016 21.7 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EEB05381.1 - 0.00022 21.5 0.0 0.96 9.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EEB05381.1 - 0.00023 20.4 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 EEB05381.1 - 0.00033 21.2 0.0 0.074 13.6 0.0 2.9 3 0 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.17 EEB05381.1 - 0.00051 19.8 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 EEB05381.1 - 0.00075 20.1 0.0 0.17 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEB05381.1 - 0.00093 19.0 0.0 0.076 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEB05381.1 - 0.0012 18.6 1.3 0.015 15.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EEB05381.1 - 0.0013 18.6 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EEB05381.1 - 0.0013 18.6 0.0 0.038 13.8 0.0 2.8 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 EEB05381.1 - 0.0033 17.3 0.3 0.62 9.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EEB05381.1 - 0.0042 17.0 0.0 4.1 7.3 0.0 3.7 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea Vps4_C PF09336.10 EEB05381.1 - 0.0069 16.4 0.0 0.33 11.0 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain T2SSE PF00437.20 EEB05381.1 - 0.008 15.3 0.0 3.5 6.6 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EEB05381.1 - 0.011 15.1 0.0 2.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 EEB05381.1 - 0.023 14.6 0.5 0.78 9.6 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 EEB05381.1 - 0.023 15.0 3.1 0.17 12.2 0.1 3.0 3 1 0 3 3 2 0 AAA domain TniB PF05621.11 EEB05381.1 - 0.032 13.6 0.0 0.44 9.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein IPT PF01745.16 EEB05381.1 - 0.032 13.6 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 EEB05381.1 - 0.037 14.5 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EEB05381.1 - 0.09 12.5 0.0 15 5.2 0.0 3.5 3 1 0 3 3 3 0 Sigma-54 interaction domain ResIII PF04851.15 EEB05381.1 - 0.16 11.9 0.0 1.3 9.0 0.0 2.5 3 1 1 4 4 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EEB05381.1 - 0.23 11.4 0.7 2.3 8.1 0.0 2.9 2 2 2 4 4 3 0 NTPase ATPase PF06745.13 EEB05381.1 - 0.83 9.0 3.0 18 4.6 0.0 3.2 3 0 0 3 3 3 0 KaiC PUF PF00806.19 EEB05382.2 - 2.1e-20 71.2 0.1 0.0012 18.4 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EEB05382.2 - 1.1e-06 28.4 0.0 4.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB05382.2 - 0.0018 18.1 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif FlgM PF04316.13 EEB05382.2 - 0.087 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM GATase PF00117.28 EEB05383.1 - 3.2e-45 154.2 0.0 4.5e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EEB05383.1 - 4.3e-44 149.4 0.0 6.6e-44 148.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EEB05383.1 - 8.5e-05 22.4 1.8 0.022 14.5 1.8 2.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EEB05383.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family ERbeta_N PF12497.8 EEB05383.1 - 0.057 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Estrogen receptor beta Glycos_transf_2 PF00535.26 EEB05384.1 - 8.1e-29 100.6 0.1 1.1e-28 100.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEB05384.1 - 2.2e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EEB05384.1 - 0.0034 17.9 0.1 0.017 15.6 0.1 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EEB05384.1 - 0.0048 16.4 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3925 PF13063.6 EEB05384.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Abhydrolase_1 PF00561.20 EEB05385.1 - 4.7e-47 160.8 0.0 6.3e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB05385.1 - 2.7e-05 24.9 0.3 4.3e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family IlvN PF07991.12 EEB05386.2 - 3.3e-46 156.9 0.1 5.2e-46 156.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EEB05386.2 - 7.9e-38 130.0 0.0 1.3e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Actin PF00022.19 EEB05387.2 - 5.3e-118 394.2 0.0 2.5e-117 391.9 0.0 1.7 1 1 0 1 1 1 1 Actin RLAN PF14401.6 EEB05387.2 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain zf-primase PF09329.11 EEB05389.2 - 1.5e-15 56.7 4.8 2.9e-15 55.8 4.8 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 EEB05389.2 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mucin PF01456.17 EEB05389.2 - 8.2 6.4 28.0 2.4 8.1 8.1 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein RNase_H2-Ydr279 PF09468.10 EEB05390.1 - 1.1e-15 58.2 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EEB05390.1 - 1.8e-07 31.3 0.0 4.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain LTXXQ PF07813.12 EEB05390.1 - 0.083 13.6 0.6 0.14 12.8 0.6 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein RNase_T PF00929.24 EEB05391.1 - 1.8e-36 126.1 0.1 2.1e-36 125.9 0.1 1.0 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.25 EEB05392.2 - 3.9e-23 82.2 0.0 5.2e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05392.2 - 2.3e-09 36.9 0.0 3.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB05392.2 - 4.5e-05 22.4 0.0 9.6e-05 21.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB05392.2 - 0.013 15.5 0.0 0.38 10.6 0.0 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family DnaJ PF00226.31 EEB05393.2 - 2.5e-28 98.0 1.1 4.1e-28 97.3 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EEB05393.2 - 2.4e-26 92.6 0.0 3.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EEB05393.2 - 6.8e-14 52.0 14.7 1.1e-13 51.3 14.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEB05393.2 - 9.7e-07 28.7 3.6 0.0029 17.5 0.6 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EEB05393.2 - 0.011 15.7 4.2 1.6 8.8 1.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EEB05393.2 - 0.045 13.4 0.8 0.045 13.4 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 EEB05393.2 - 0.15 12.6 9.0 0.43 11.1 8.9 1.8 1 1 0 1 1 1 0 Cytochrome c3 Zn-ribbon_8 PF09723.10 EEB05393.2 - 8.8 6.5 10.7 7.1 6.8 0.2 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Tim54 PF11711.8 EEB05394.1 - 2.2e-68 230.8 0.1 4.7e-68 229.7 0.1 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RNase_H2_suC PF08615.11 EEB05394.1 - 0.038 14.2 0.0 0.076 13.2 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pil1 PF13805.6 EEB05395.1 - 9.2e-58 195.8 0.3 1.4e-57 195.3 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 WLM PF08325.10 EEB05396.1 - 3.2e-37 128.5 0.1 5.1e-37 127.8 0.1 1.4 1 1 0 1 1 1 1 WLM domain Reprolysin_3 PF13582.6 EEB05396.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SprT-like PF10263.9 EEB05396.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.8 1 0 0 1 1 1 0 SprT-like family DUF4171 PF13775.6 EEB05396.1 - 0.13 12.8 5.0 0.19 12.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Reprolysin_5 PF13688.6 EEB05396.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12 DUF45 PF01863.17 EEB05396.1 - 0.22 11.5 4.9 0.45 10.5 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF45 NAD_Gly3P_dh_N PF01210.23 EEB05397.1 - 2.1e-55 187.0 0.0 8.3e-55 185.1 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EEB05397.1 - 8.8e-45 152.5 0.1 1.6e-44 151.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EEB05397.1 - 0.00028 21.4 1.2 0.0044 17.6 1.2 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EEB05397.1 - 0.0076 16.1 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 1 Rossmann-like domain zf-LYAR PF08790.11 EEB05398.1 - 3.7e-15 55.5 2.9 8.8e-15 54.3 2.9 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger ORC6 PF05460.13 EEB05398.1 - 0.072 12.4 14.8 0.088 12.1 14.8 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf_UBZ PF18439.1 EEB05398.1 - 0.079 12.6 0.4 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Dicty_REP PF05086.12 EEB05398.1 - 0.23 9.4 11.9 0.26 9.2 11.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RP-C_C PF11800.8 EEB05398.1 - 0.5 10.4 8.0 0.82 9.7 8.0 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.17 EEB05398.1 - 0.82 9.8 8.6 0.97 9.5 8.6 1.2 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 EEB05398.1 - 2.9 6.8 14.0 3.2 6.7 14.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 EEB05398.1 - 6.7 6.5 17.3 8.2 6.2 17.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EEB05398.1 - 6.7 5.4 14.7 7.6 5.2 14.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EEB05398.1 - 7.7 4.5 12.1 8.7 4.3 12.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EEB05398.1 - 8.4 5.5 8.4 9.7 5.3 8.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Iwr1 PF08574.10 EEB05398.1 - 9.6 7.3 8.9 7.1 7.7 7.1 1.7 1 1 1 2 2 2 0 Transcription factor Iwr1 PWWP PF00855.17 EEB05399.1 - 2e-15 56.9 0.0 2e-15 56.9 0.0 2.5 2 0 0 2 2 2 1 PWWP domain BSP_II PF05432.11 EEB05399.1 - 0.0072 16.1 29.6 0.0072 16.1 29.6 3.2 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) CPSase_L_D2 PF02786.17 EEB05400.2 - 8e-76 254.2 0.3 3.8e-29 101.7 0.0 3.3 2 1 1 3 3 3 3 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EEB05400.2 - 3.1e-40 137.3 0.0 7e-40 136.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EEB05400.2 - 9.6e-14 51.3 0.0 1.1e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EEB05400.2 - 2.4e-12 46.7 0.0 6.8e-05 22.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 EEB05400.2 - 3.6e-08 33.2 0.8 1.1e-06 28.4 0.1 2.7 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 EEB05400.2 - 4.4e-05 23.0 0.0 0.025 14.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 EEB05400.2 - 7e-05 22.9 0.2 0.013 15.6 0.0 2.9 2 1 1 3 3 3 1 ATP-grasp domain RimK PF08443.11 EEB05400.2 - 0.00016 21.3 0.0 0.068 12.8 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 EEB05400.2 - 0.00095 19.0 0.6 0.037 13.8 0.1 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.22 EEB05400.2 - 0.0053 16.9 0.1 0.032 14.4 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Peptidase_M17_N PF02789.17 EEB05400.2 - 0.01 15.7 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Epimerase PF01370.21 EEB05400.2 - 0.046 13.2 0.1 0.21 11.0 0.1 2.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LAMTOR5 PF16672.5 EEB05400.2 - 0.17 11.8 0.1 0.47 10.4 0.1 1.7 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Thiolase_N PF00108.23 EEB05401.1 - 3.3e-88 295.4 5.9 4.7e-88 294.9 5.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEB05401.1 - 3.4e-45 152.7 0.2 1.2e-44 150.9 0.2 2.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEB05401.1 - 0.0023 17.6 1.9 0.014 15.0 1.0 2.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain GTP_EFTU PF00009.27 EEB05402.1 - 3.2e-45 154.0 0.0 5e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EEB05402.1 - 1.2e-36 125.9 5.8 2e-36 125.3 5.8 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EEB05402.1 - 5.2e-22 77.9 0.0 1.1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EEB05402.1 - 1e-21 76.7 0.0 2.5e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB05402.1 - 1.3e-08 35.1 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB05402.1 - 3.4e-05 23.9 0.1 6.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EEB05402.1 - 7.7e-05 22.7 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EEB05402.1 - 0.0027 17.2 0.1 0.0062 16.0 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EEB05402.1 - 0.018 15.2 0.1 0.062 13.5 0.1 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EEB05402.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Snf7 PF03357.21 EEB05404.1 - 9.2e-25 87.2 9.0 1.1e-24 86.9 9.0 1.1 1 0 0 1 1 1 1 Snf7 Flt3_lig PF02947.14 EEB05404.1 - 0.12 12.6 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 flt3 ligand DUF4844 PF16133.5 EEB05404.1 - 0.12 12.9 1.3 4.2 7.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) Nnf1 PF03980.14 EEB05405.1 - 3.1e-20 72.6 1.2 3.1e-20 72.6 1.2 2.1 1 1 1 2 2 2 1 Nnf1 Spc7 PF08317.11 EEB05405.1 - 0.00066 18.7 0.7 0.00079 18.4 0.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EEB05405.1 - 0.0014 18.8 4.7 0.0014 18.8 4.7 2.3 2 1 0 2 2 2 1 ABC transporter C-terminal domain HrpB7 PF09486.10 EEB05405.1 - 0.0045 17.4 0.1 0.0099 16.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) LUC7 PF03194.15 EEB05405.1 - 0.01 15.5 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 LUC7 N_terminus CC2-LZ PF16516.5 EEB05405.1 - 0.013 15.9 1.3 0.035 14.5 1.3 1.8 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMF_DNA_bd PF12329.8 EEB05405.1 - 0.013 15.5 3.2 0.013 15.5 3.2 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 EEB05405.1 - 0.015 15.4 0.3 0.038 14.0 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LIF_OSM PF01291.17 EEB05405.1 - 0.021 15.0 0.6 0.045 13.9 0.4 1.6 1 1 0 1 1 1 0 LIF / OSM family Helo_like_N PF17111.5 EEB05405.1 - 0.05 13.0 1.7 2.6 7.4 1.1 2.2 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins TPD52 PF04201.15 EEB05405.1 - 0.063 12.9 0.9 0.24 11.0 0.4 2.1 2 1 0 2 2 2 0 Tumour protein D52 family Endotoxin_N PF03945.14 EEB05405.1 - 0.099 12.3 0.3 0.3 10.8 0.1 1.8 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain FlxA PF14282.6 EEB05405.1 - 0.13 12.2 4.6 0.91 9.5 4.2 2.2 1 1 0 1 1 1 0 FlxA-like protein DUF1192 PF06698.11 EEB05405.1 - 0.6 10.2 4.5 1.8 8.7 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) HR1 PF02185.16 EEB05405.1 - 0.7 10.1 9.5 39 4.4 5.7 3.4 2 1 0 2 2 2 0 Hr1 repeat YlqD PF11068.8 EEB05405.1 - 0.98 9.8 7.9 0.8 10.1 4.0 2.5 2 1 0 2 2 2 0 YlqD protein MerR-DNA-bind PF09278.11 EEB05405.1 - 1.3 9.7 8.2 0.58 10.7 1.4 2.7 2 1 1 3 3 2 0 MerR, DNA binding Osmo_CC PF08946.10 EEB05405.1 - 1.3 9.3 8.1 1.9 8.8 0.7 3.3 3 1 1 4 4 4 0 Osmosensory transporter coiled coil DivIC PF04977.15 EEB05405.1 - 9.5 6.1 9.5 4.3 7.2 2.3 2.7 2 1 1 3 3 3 0 Septum formation initiator PMSR PF01625.21 EEB05406.1 - 3.1e-62 209.3 0.3 3.6e-62 209.1 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase tRNA-synt_1e PF01406.19 EEB05407.1 - 2.6e-140 467.0 0.2 4.3e-140 466.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EEB05407.1 - 2.1e-10 39.9 0.9 3e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEB05407.1 - 6.5e-06 24.7 0.0 3.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EEB05407.1 - 0.00024 20.1 0.6 0.019 13.9 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (K) DALR_2 PF09190.11 EEB05407.1 - 0.013 16.0 0.0 0.067 13.7 0.0 2.3 1 0 0 1 1 1 0 DALR domain tRNA-synt_1c PF00749.21 EEB05407.1 - 0.032 13.1 5.2 0.06 12.2 0.0 2.8 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain Regnase_1_C PF18561.1 EEB05407.1 - 0.097 12.4 1.1 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain TBP PF00352.21 EEB05408.1 - 7.5e-68 224.5 0.1 7.5e-33 112.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EEB05408.1 - 3.3e-05 23.9 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EEB05408.1 - 0.095 12.5 0.2 0.57 10.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Peptidase_C71 PF12386.8 EEB05408.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei NST1 PF13945.6 EEB05410.1 - 8.9e-58 195.6 8.0 8.9e-58 195.6 8.0 5.9 5 1 1 6 6 6 2 Salt tolerance down-regulator Ras PF00071.22 EEB05411.2 - 6.8e-51 172.1 0.0 8.1e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB05411.2 - 5.5e-23 81.5 0.0 9.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB05411.2 - 4.7e-06 26.2 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB05411.2 - 0.0016 17.8 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EEB05411.2 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EEB05411.2 - 0.076 12.8 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.22 EEB05412.2 - 7.4e-30 102.6 0.1 4.9e-14 51.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEB05412.2 - 0.0037 17.3 0.0 0.064 13.3 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 EEB05412.2 - 0.0071 16.4 0.0 0.046 13.8 0.0 2.1 2 0 0 2 2 2 1 Limkain b1 CTP_transf_1 PF01148.20 EEB05413.2 - 2.4e-85 286.5 20.4 2.9e-85 286.3 20.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Fumble PF03630.14 EEB05414.1 - 1e-136 455.5 0.1 1.2e-136 455.2 0.1 1.1 1 0 0 1 1 1 1 Fumble NCA2 PF08637.10 EEB05415.1 - 1.9e-85 286.5 1.6 3.4e-85 285.7 1.6 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 LCD1 PF09798.9 EEB05416.1 - 6.3e-20 71.2 22.4 1.3e-17 63.6 9.3 3.0 3 0 0 3 3 3 2 DNA damage checkpoint protein DUF1192 PF06698.11 EEB05416.1 - 0.25 11.4 1.4 0.79 9.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HIP1_clath_bdg PF16515.5 EEB05416.1 - 4.6 7.9 22.2 9.6 6.9 8.1 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ras PF00071.22 EEB05417.1 - 2.9e-67 225.3 0.2 3.5e-67 225.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB05417.1 - 8.5e-35 119.6 0.0 1.6e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB05417.1 - 2.9e-14 52.9 0.1 3.7e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB05417.1 - 8.1e-06 25.4 0.1 1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEB05417.1 - 7e-05 22.8 0.2 0.26 11.2 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEB05417.1 - 0.00015 21.4 0.1 0.00042 19.9 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEB05417.1 - 0.00032 20.7 0.0 0.0005 20.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EEB05417.1 - 0.00062 19.2 0.1 0.00079 18.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEB05417.1 - 0.028 14.0 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EEB05417.1 - 0.036 14.4 0.1 0.062 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NPHI_C PF08469.10 EEB05417.1 - 0.053 13.5 1.6 0.57 10.2 0.1 2.1 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal AAA_29 PF13555.6 EEB05417.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EEB05417.1 - 0.068 12.2 0.0 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 EEB05417.1 - 0.083 13.2 0.1 0.63 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EEB05417.1 - 0.094 13.1 0.1 2 8.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB05417.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thr_synth_N PF14821.6 EEB05418.1 - 1.7e-28 98.7 0.0 4e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EEB05418.1 - 4.7e-19 68.9 0.0 1.2e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NARP1 PF12569.8 EEB05419.1 - 0.23 10.3 6.3 0.35 9.7 6.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 EEB05419.1 - 2.6 8.0 5.1 3.5 7.6 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UAA PF08449.11 EEB05420.1 - 8e-93 310.9 14.7 9.1e-93 310.8 14.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EEB05420.1 - 3.4e-05 24.0 25.0 0.00049 20.3 8.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EEB05420.1 - 0.0016 17.7 1.2 0.0016 17.7 1.2 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 EEB05420.1 - 0.0035 16.7 10.2 0.0082 15.5 10.2 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family HECT_2 PF09814.9 EEB05421.1 - 2.1e-28 99.3 0.3 3.4e-28 98.6 0.3 1.3 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.7 EEB05421.1 - 0.0071 16.3 0.5 0.48 10.5 0.2 2.3 2 0 0 2 2 2 1 Double zinc ribbon DUF678 PF05077.12 EEB05421.1 - 0.048 13.8 0.6 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF678) BIR PF00653.21 EEB05421.1 - 0.1 13.3 1.2 0.84 10.3 0.0 2.6 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain Cytochrome_C7 PF14522.6 EEB05421.1 - 0.12 12.4 0.7 0.26 11.3 0.7 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Gin PF10764.9 EEB05421.1 - 0.13 12.3 0.5 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin SR1P PF13790.6 EEB05421.1 - 0.14 12.3 1.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 SR1 protein zf-LITAF-like PF10601.9 EEB05421.1 - 0.3 11.4 4.3 2 8.8 0.3 2.8 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-CCHC PF00098.23 EEB05421.1 - 2.2 8.5 6.5 1.6 8.9 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_C PF01556.18 EEB05422.1 - 5.2e-39 133.7 0.0 6.8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEB05422.1 - 1.9e-25 88.8 0.8 3e-25 88.1 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEB05422.1 - 4.3e-17 62.2 15.6 6.8e-17 61.6 15.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEB05422.1 - 0.00099 19.0 16.3 0.0036 17.2 2.7 2.7 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EEB05422.1 - 0.0067 16.4 10.5 0.061 13.3 2.3 2.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 EEB05422.1 - 0.33 11.0 7.9 30 4.7 0.0 3.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 EEB05422.1 - 0.55 10.3 9.2 15 5.7 9.2 2.2 1 1 0 1 1 1 0 zinc-ribbons DUF2614 PF11023.8 EEB05422.1 - 1.5 8.9 6.0 11 6.2 0.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DZR PF12773.7 EEB05422.1 - 3.2 7.8 11.1 3.2e+02 1.4 11.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon Cytochrome_C7 PF14522.6 EEB05422.1 - 7.3 6.7 7.6 42 4.2 7.8 2.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Glyco_transf_22 PF03901.17 EEB05423.2 - 4.5e-37 128.3 30.2 5.4e-37 128.0 30.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Inhibitor_I78 PF11720.8 EEB05423.2 - 5.7e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EEB05423.2 - 0.025 15.2 0.0 0.054 14.2 0.0 1.5 1 0 0 1 1 1 0 Potato inhibitor I family ATP-synt PF00231.19 EEB05424.1 - 2.2e-71 240.8 6.1 2.7e-71 240.6 6.1 1.1 1 0 0 1 1 1 1 ATP synthase DSBA PF01323.20 EEB05424.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CKS PF01111.19 EEB05425.1 - 4.6e-33 113.3 0.2 6.4e-33 112.8 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 EEB05426.1 - 2.4e-43 146.1 2.9 2.7e-21 75.4 0.7 2.3 2 0 0 2 2 2 2 Bromodomain PAH PF02671.21 EEB05427.1 - 3.9e-34 116.5 14.2 1.9e-15 56.7 0.2 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 EEB05427.1 - 3.6e-32 112.2 1.8 1e-27 97.7 0.0 2.5 1 1 1 2 2 2 2 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EEB05427.1 - 9.8e-18 64.0 0.1 2.7e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Chitin_synth_1 PF01644.17 EEB05428.1 - 2.1e-55 187.1 0.2 3.3e-55 186.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEB05428.1 - 2.3e-22 78.7 0.0 5.3e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEB05428.1 - 8.7e-05 21.3 3.5 0.00016 20.4 0.4 2.1 2 0 0 2 2 2 1 Chitin synthase CDP-OH_P_tran_2 PF08009.11 EEB05428.1 - 0.25 11.3 3.8 0.71 9.8 3.8 1.8 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 TRAM1 PF08390.11 EEB05428.1 - 0.61 9.8 3.8 1.8 8.3 3.8 1.8 1 0 0 1 1 1 0 TRAM1-like protein DUF2933 PF11666.8 EEB05428.1 - 7.2 6.7 10.2 2.8 8.1 3.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2933) tRNA-synt_1 PF00133.22 EEB05429.1 - 8.9e-222 737.6 0.0 2.2e-220 733.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEB05429.1 - 3.6e-32 111.4 0.9 7.6e-32 110.4 0.9 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEB05429.1 - 2.2e-18 66.2 0.9 1.8e-10 40.2 0.0 4.8 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EEB05429.1 - 3.2e-11 43.1 5.4 3.6e-08 33.1 0.1 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EEB05429.1 - 0.00032 20.2 0.0 0.18 11.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 EEB05429.1 - 0.084 11.7 0.0 0.084 11.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1b PF00579.25 EEB05429.1 - 0.093 12.0 0.1 2 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PepSY PF03413.19 EEB05429.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain ATP-synt_B PF00430.18 EEB05429.1 - 0.43 10.7 7.3 0.92 9.6 7.3 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Amidohydro_2 PF04909.14 EEB05430.1 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EEB05430.1 - 6.4e-05 22.4 0.0 0.0045 16.3 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Chlam_PMP PF02415.17 EEB05431.1 - 0.0091 16.4 1.2 0.081 13.4 0.1 2.6 2 0 0 2 2 2 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CPP1-like PF11833.8 EEB05431.1 - 0.62 9.7 5.6 2.9 7.5 0.5 3.1 2 2 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Cwf_Cwc_15 PF04889.12 EEB05432.1 - 1.1e-76 257.9 26.3 1.2e-76 257.7 26.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 EEB05432.1 - 0.014 14.8 21.5 0.017 14.6 21.5 1.2 1 0 0 1 1 1 0 SDA1 PAS PF00989.25 EEB05432.1 - 0.087 12.8 1.3 0.2 11.6 1.3 1.6 1 0 0 1 1 1 0 PAS fold Myc_N PF01056.18 EEB05432.1 - 0.11 12.3 12.2 0.14 12.0 12.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 EEB05432.1 - 0.92 7.7 20.3 1.2 7.4 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EEB05432.1 - 2.3 6.2 16.5 2.9 5.9 16.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Usp PF00582.26 EEB05432.1 - 2.8 8.4 7.1 9 6.8 2.1 2.3 2 0 0 2 2 2 0 Universal stress protein family DUF913 PF06025.12 EEB05432.1 - 3.5 6.5 9.6 4.7 6.1 9.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 EEB05432.1 - 5.1 6.3 20.2 9.5 5.4 20.3 1.4 1 1 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 EEB05432.1 - 6.5 5.4 13.8 8.4 5.0 13.8 1.2 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 EEB05432.1 - 8.5 6.2 5.0 14 5.5 5.0 1.5 1 0 0 1 1 1 0 VIT family Cpn60_TCP1 PF00118.24 EEB05433.2 - 2.6e-156 521.1 8.4 3e-156 520.9 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 EEB05433.2 - 0.038 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 EAL domain AAA_5 PF07728.14 EEB05433.2 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TetR_C_14 PF17754.1 EEB05433.2 - 0.13 12.2 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 MftR C-terminal domain Rep_fac_C PF08542.11 EEB05433.2 - 0.13 12.7 0.1 0.78 10.2 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain CTD_bind PF04818.13 EEB05434.1 - 3e-15 56.8 0.3 3e-15 56.8 0.3 2.8 4 0 0 4 4 4 1 RNA polymerase II-binding domain. zf-CpG_bind_C PF12269.8 EEB05434.1 - 0.016 15.0 0.3 0.2 11.4 0.2 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain CTK3 PF12243.8 EEB05434.1 - 0.022 14.8 0.8 0.043 13.8 0.2 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 COX17 PF05051.13 EEB05435.1 - 3.6e-21 75.3 5.7 4.4e-21 75.0 5.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Dermcidin PF15291.6 EEB05435.1 - 0.13 12.9 0.7 0.14 12.8 0.7 1.1 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Nt_Gln_amidase PF09764.9 EEB05436.2 - 3.5e-58 196.3 0.0 4.6e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase Peptidase_M14 PF00246.24 EEB05437.1 - 6e-75 252.7 0.0 8.1e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EEB05437.1 - 0.022 15.1 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase activation peptide SelP_N PF04592.14 EEB05437.1 - 0.61 9.5 4.1 1 8.7 4.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ubiquitin PF00240.23 EEB05438.1 - 4.7e-168 545.3 27.6 4.8e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EEB05438.1 - 4.4e-79 260.3 28.3 2.9e-15 55.8 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB05438.1 - 8e-28 96.7 14.7 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB05438.1 - 5.7e-20 71.0 5.6 0.038 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB05438.1 - 2.8e-18 66.1 11.7 0.042 14.2 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB05438.1 - 2.3e-17 63.1 4.7 0.18 11.9 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEB05438.1 - 7.2e-16 58.6 2.8 0.49 11.0 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EEB05438.1 - 3.5e-13 49.7 1.6 0.98 9.2 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 EEB05438.1 - 3.2e-08 33.2 1.3 2.6 7.3 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 EEB05438.1 - 1e-07 31.9 32.0 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 EEB05438.1 - 2.5e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 EEB05438.1 - 5.4e-07 29.7 5.3 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EEB05438.1 - 1.7e-06 27.8 7.7 14 5.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 EEB05438.1 - 2.5e-06 28.2 0.6 71 4.3 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EEB05438.1 - 1.4e-05 25.1 7.4 9.9 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EEB05438.1 - 3.1e-05 23.5 0.0 32 3.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EEB05438.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 EEB05438.1 - 0.00041 20.4 9.7 38 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ORF11CD3 PF10549.9 EEB05438.1 - 0.00069 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 EEB05438.1 - 0.0018 18.8 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 EEB05438.1 - 0.024 13.6 0.0 85 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 EEB05438.1 - 0.14 12.3 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EEB05438.1 - 0.2 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 EEB05438.1 - 0.23 11.0 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 EEB05438.1 - 0.29 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 EEB05438.1 - 5.7 6.7 13.6 1.3e+02 2.4 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Erg28 PF03694.13 EEB05439.1 - 8.2e-41 138.8 1.5 1e-40 138.5 1.5 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.16 EEB05439.1 - 0.014 15.4 0.5 0.025 14.6 0.5 1.5 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PspA_IM30 PF04012.12 EEB05440.1 - 0.0018 17.9 1.8 0.0023 17.6 1.8 1.1 1 0 0 1 1 1 1 PspA/IM30 family ATG16 PF08614.11 EEB05440.1 - 0.0036 17.5 3.4 0.0043 17.3 3.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 EEB05440.1 - 0.007 17.2 4.1 0.007 17.2 4.1 1.4 2 0 0 2 2 1 1 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 EEB05440.1 - 0.012 14.7 1.5 0.014 14.5 1.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Casc1_N PF15927.5 EEB05440.1 - 0.022 14.4 5.8 0.032 13.9 5.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF1854 PF08909.11 EEB05440.1 - 0.026 14.3 0.2 0.037 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) PIN_9 PF18477.1 EEB05440.1 - 0.052 13.9 0.1 0.07 13.4 0.1 1.1 1 0 0 1 1 1 0 PIN like domain DUF724 PF05266.14 EEB05440.1 - 0.099 12.5 4.3 0.14 12.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tox-ODYAM1 PF15642.6 EEB05440.1 - 0.1 11.6 3.3 0.12 11.3 3.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus SNCAIP_SNCA_bd PF16700.5 EEB05440.1 - 0.14 11.9 0.5 0.14 11.9 0.5 2.3 2 1 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain XhlA PF10779.9 EEB05440.1 - 0.15 12.3 0.7 0.22 11.8 0.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA TMPIT PF07851.13 EEB05440.1 - 0.21 10.8 3.4 0.26 10.5 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EEB05440.1 - 0.46 9.3 1.7 0.46 9.3 1.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CIAPIN1 PF05093.13 EEB05441.1 - 3.1e-30 104.6 4.4 3.1e-30 104.6 4.4 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EEB05441.1 - 6.2e-24 84.7 0.0 2.1e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus DALR_1 PF05746.15 EEB05441.1 - 0.064 13.4 0.7 3.3 7.9 0.0 2.4 2 1 0 2 2 2 0 DALR anticodon binding domain zf-CCCH PF00642.24 EEB05442.1 - 4.2e-10 39.3 31.8 0.012 15.6 1.9 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEB05442.1 - 7.3e-06 25.9 41.7 0.0018 18.3 4.9 6.0 6 1 0 6 6 6 4 Zinc finger domain zf-CCCH_4 PF18044.1 EEB05442.1 - 4.3e-05 23.2 37.4 0.0024 17.6 0.4 6.2 5 2 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEB05442.1 - 0.0038 17.6 2.3 0.0038 17.6 2.3 5.2 4 1 1 5 5 5 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EEB05442.1 - 0.012 15.8 21.8 0.11 12.7 8.6 3.7 1 1 2 3 3 3 0 Zinc-finger containing family Torus PF16131.5 EEB05442.1 - 0.14 12.8 0.1 0.14 12.8 0.1 6.3 3 1 4 7 7 7 0 Torus domain zf_CCCH_5 PF18384.1 EEB05442.1 - 7.2 6.8 8.9 17 5.7 0.3 3.3 3 0 0 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) Gtr1_RagA PF04670.12 EEB05443.1 - 1.1e-100 335.8 0.6 1.3e-100 335.5 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EEB05443.1 - 4.9e-09 36.4 0.0 1.3e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEB05443.1 - 3.4e-08 33.2 0.0 3.4e-08 33.2 0.0 1.9 3 0 0 3 3 3 1 Ras family MMR_HSR1 PF01926.23 EEB05443.1 - 5.2e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EEB05443.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB05443.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.13 EEB05443.1 - 0.00092 18.4 0.7 0.013 14.7 0.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) G-alpha PF00503.20 EEB05443.1 - 0.029 13.6 4.3 0.31 10.2 0.2 2.6 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 EEB05443.1 - 0.048 13.6 0.7 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EEB05443.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EEB05443.1 - 0.067 13.7 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Brix PF04427.18 EEB05443.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Brix domain RNA_pol_Rpb4 PF03874.16 EEB05444.1 - 7.7e-23 81.1 0.1 1.1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 COQ7 PF03232.13 EEB05445.1 - 2.9e-70 235.5 0.0 3.7e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EEB05445.1 - 0.0023 18.3 0.0 0.006 17.0 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Aminopep PF10023.9 EEB05445.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative aminopeptidase Enolase_C PF00113.22 EEB05447.1 - 1.7e-147 490.4 0.0 2.4e-147 489.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EEB05447.1 - 2e-58 196.3 0.3 3.8e-58 195.3 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EEB05447.1 - 3e-09 36.8 0.0 6.4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EEB05447.1 - 0.0076 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Complex1_LYR PF05347.15 EEB05448.1 - 0.0012 18.8 0.9 0.0012 18.8 0.9 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEB05448.1 - 0.0015 19.2 0.4 0.0041 17.8 0.4 1.8 1 0 0 1 1 1 1 Complex1_LYR-like HAD PF12710.7 EEB05449.1 - 0.023 15.1 0.1 0.087 13.2 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CPSase_L_D2 PF02786.17 EEB05450.2 - 8.2e-80 267.2 0.0 1.4e-79 266.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EEB05450.2 - 1.4e-68 230.6 0.0 2.2e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EEB05450.2 - 7.9e-41 139.0 0.1 1.7e-40 138.0 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEB05450.2 - 4.9e-31 107.0 0.0 1.6e-30 105.4 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EEB05450.2 - 4.4e-25 88.7 0.0 1e-24 87.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EEB05450.2 - 2.6e-14 52.8 0.7 6.4e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEB05450.2 - 4.7e-10 39.1 0.2 0.00041 20.1 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EEB05450.2 - 4.8e-08 32.8 0.0 9.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEB05450.2 - 2.7e-06 27.0 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EEB05450.2 - 0.00022 21.9 0.2 0.74 10.5 0.0 3.1 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EEB05450.2 - 0.00028 20.2 0.4 0.29 10.3 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EEB05450.2 - 0.00082 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EEB05450.2 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EEB05450.2 - 0.098 12.3 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Ribosomal_L5_C PF00673.21 EEB05451.1 - 1.1e-21 76.8 0.0 1.6e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEB05451.1 - 3.9e-19 68.7 0.0 1.3e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EEB05451.1 - 0.055 13.2 0.4 0.1 12.3 0.1 1.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain eIF2_C PF09173.11 EEB05452.1 - 3.4e-35 120.1 0.6 8.6e-35 118.9 0.6 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EEB05452.1 - 2.5e-24 85.9 0.3 2.1e-23 82.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EEB05452.1 - 6.9e-12 45.6 0.5 1.7e-11 44.4 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EEB05452.1 - 0.002 18.1 0.2 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EEB05452.1 - 0.0035 17.3 0.2 0.0076 16.3 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EEB05452.1 - 0.0043 17.1 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EEB05452.1 - 0.16 11.1 0.2 0.98 8.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit ArfGap PF01412.18 EEB05453.2 - 7.8e-34 116.2 1.4 1.3e-33 115.5 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EEB05453.2 - 2.5e-15 56.8 4.3 6.1e-15 55.6 4.3 1.6 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EEB05453.2 - 1.9e-10 41.2 1.2 4.2e-10 40.1 0.0 2.2 2 1 0 2 2 2 1 PH domain BAR PF03114.18 EEB05453.2 - 0.0067 16.1 4.5 0.0067 16.1 4.5 2.9 2 1 1 3 3 3 1 BAR domain RP-C_C PF11800.8 EEB05453.2 - 0.17 11.9 1.6 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Ribosomal_S24e PF01282.19 EEB05454.1 - 5.7e-33 112.7 0.2 1.1e-32 111.8 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein S24e RRXRR PF14239.6 EEB05454.1 - 0.0057 16.5 3.8 0.0062 16.4 3.5 1.3 1 1 0 1 1 1 1 RRXRR protein Acetyltransf_8 PF13523.6 EEB05455.1 - 1.6e-44 151.1 0.1 2.1e-44 150.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pro_isomerase PF00160.21 EEB05456.1 - 1.1e-32 113.5 0.0 2e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EEB05456.1 - 1.6e-16 59.9 0.1 2.6e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB05456.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleopor_Nup85 PF07575.13 EEB05457.1 - 2.4e-134 449.0 9.2 2.8e-134 448.8 9.2 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF384 PF04064.13 EEB05458.2 - 0.028 14.3 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF384) dsrm PF00035.26 EEB05459.1 - 1e-06 29.3 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 EEB05459.1 - 0.00089 19.4 0.1 0.0021 18.2 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain RRM_1 PF00076.22 EEB05460.1 - 5.3e-47 157.5 0.0 5.5e-16 58.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB05460.1 - 0.00061 19.9 0.3 0.049 13.7 0.0 3.1 3 2 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 EEB05460.1 - 0.0013 18.8 0.0 0.0066 16.5 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EEB05460.1 - 0.0034 17.2 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEB05460.1 - 0.0042 17.0 0.1 0.092 12.8 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EEB05460.1 - 0.01 15.4 0.0 0.04 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 EEB05461.2 - 4.1e-63 213.2 0.2 7.5e-63 212.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB05461.2 - 8.3e-17 61.5 0.0 2.1e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EEB05461.2 - 1.9e-06 27.6 4.2 2.5e-05 24.0 4.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB05461.2 - 7.3e-06 25.9 5.3 1e-05 25.5 1.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEB05461.2 - 2.1e-05 24.3 4.4 5e-05 23.1 4.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EEB05461.2 - 0.0002 21.4 0.0 0.0006 19.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EEB05461.2 - 0.00058 20.1 7.9 0.004 17.5 3.1 2.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EEB05461.2 - 0.00083 19.2 5.4 0.0026 17.6 5.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EEB05461.2 - 0.0021 17.9 3.8 0.0021 17.9 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EEB05461.2 - 0.0047 16.2 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EEB05461.2 - 0.012 15.5 5.2 0.041 13.9 5.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EEB05461.2 - 0.11 12.6 6.2 0.09 13.0 1.7 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EEB05461.2 - 0.12 12.3 0.6 0.28 11.1 0.6 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CN_hydrolase PF00795.22 EEB05462.1 - 8.6e-18 64.6 0.0 8.7e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase BP28CT PF08146.12 EEB05463.2 - 4.1e-32 111.2 1.9 2.9e-31 108.5 1.9 2.6 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EEB05463.2 - 3.2e-16 59.7 1.2 3.2e-16 59.7 1.2 5.7 5 1 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 EEB05463.2 - 0.0011 19.4 0.1 4.8 7.8 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat Peptidase_M24_C PF16188.5 EEB05463.2 - 0.0013 18.7 0.5 0.0061 16.6 0.5 2.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 HEAT PF02985.22 EEB05463.2 - 0.0068 16.6 1.9 28 5.3 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat tRNA-Thr_ED PF08915.11 EEB05463.2 - 0.079 13.0 1.7 0.25 11.4 1.7 1.9 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Herpes_UL17 PF04559.12 EEB05463.2 - 0.11 11.3 0.3 5.2 5.8 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL17 protein Peptidase_M24 PF00557.24 EEB05464.1 - 9.2e-09 35.3 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DHBP_synthase PF00926.19 EEB05465.1 - 1.4e-87 292.2 0.1 1.6e-87 292.0 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF2140 PF09911.9 EEB05466.1 - 0.17 11.4 4.6 0.47 10.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) Pyr_redox_3 PF13738.6 EEB05466.1 - 4.2 6.5 7.1 0.53 9.5 1.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 EEB05467.1 - 1.1e-126 423.1 0.0 1.3e-126 422.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Spt4 PF06093.13 EEB05468.1 - 6.2e-23 80.7 0.0 7.8e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF4448 PF14610.6 EEB05469.1 - 1.3e-21 77.2 0.1 1.5e-21 77.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Alpha-amylase PF00128.24 EEB05470.1 - 2.6e-55 188.3 0.3 4.7e-55 187.5 0.3 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EEB05470.1 - 0.0099 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_70 PF02324.16 EEB05470.1 - 0.067 11.4 0.0 0.52 8.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Pkinase PF00069.25 EEB05471.1 - 1.1e-38 133.2 0.0 2.4e-34 118.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05471.1 - 9.4e-12 44.8 0.0 4.7e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EEB05471.1 - 0.0001 22.3 0.1 0.0022 18.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EEB05471.1 - 0.16 11.2 0.1 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase SBDS PF01172.18 EEB05472.1 - 1.6e-17 63.3 0.0 2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_2 PF00152.20 EEB05473.1 - 4.2e-76 256.0 0.0 6.1e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEB05473.1 - 8.3e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEB05473.1 - 2.4e-06 27.2 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Mpp10 PF04006.12 EEB05473.1 - 0.065 11.7 8.2 0.11 10.9 8.2 1.3 1 0 0 1 1 1 0 Mpp10 protein DUF953 PF06110.11 EEB05474.1 - 1.2e-13 50.7 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) TUG-UBL1 PF11470.8 EEB05475.2 - 6.4e-17 61.5 0.2 6.9e-16 58.2 0.1 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EEB05475.2 - 0.00022 21.4 0.2 0.002 18.3 0.1 2.7 3 1 0 3 3 3 1 UBX domain ubiquitin PF00240.23 EEB05475.2 - 0.11 12.3 0.2 32 4.4 0.0 3.2 4 0 0 4 4 4 0 Ubiquitin family RibD_C PF01872.17 EEB05476.1 - 5.5e-28 98.2 0.0 6.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain GalP_UDP_tr_C PF02744.17 EEB05476.1 - 0.099 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain FAA_hydrolase PF01557.18 EEB05477.1 - 7.2e-49 166.4 0.0 8.6e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TFIIE_beta PF02186.15 EEB05477.1 - 0.19 12.1 0.0 0.73 10.2 0.0 1.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain Aminotran_3 PF00202.21 EEB05478.1 - 2e-114 382.4 0.0 2.3e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PhoH PF02562.16 EEB05478.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC1 PF03109.16 EEB05479.1 - 4.3e-24 85.0 0.0 7.7e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EEB05479.1 - 0.077 12.9 0.1 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L34 PF00468.17 EEB05480.1 - 2.4e-18 65.8 9.5 3.4e-18 65.3 9.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 SF3A2 PF16835.5 EEB05481.2 - 2.3e-36 124.1 0.0 3.7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EEB05481.2 - 1.2e-06 28.7 0.7 2.4e-06 27.8 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EEB05481.2 - 4.5e-06 26.6 0.2 6.3e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EEB05481.2 - 0.02 14.5 1.5 0.034 13.7 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF2214 PF09980.9 EEB05482.1 - 0.1 12.4 0.2 0.13 12.1 0.2 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2214) Methyltransf_23 PF13489.6 EEB05483.2 - 7.1e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB05483.2 - 1.1e-14 55.0 0.0 4.3e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB05483.2 - 1.4e-14 54.6 0.0 1.1e-13 51.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB05483.2 - 2.2e-11 44.3 0.0 8.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB05483.2 - 4.1e-11 42.9 0.0 6.1e-10 39.1 0.0 2.4 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EEB05483.2 - 2.3e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EEB05483.2 - 4.5e-05 23.4 0.0 0.0041 17.0 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 EEB05483.2 - 0.00017 20.9 0.0 0.016 14.4 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family TehB PF03848.14 EEB05483.2 - 0.00019 20.9 0.0 0.00051 19.5 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EEB05483.2 - 0.0011 18.5 0.1 0.0063 16.0 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase TPMT PF05724.11 EEB05483.2 - 0.002 17.8 0.0 0.002 17.8 0.0 2.1 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EEB05483.2 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 EEB05483.2 - 0.14 13.2 0.0 0.31 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.23 EEB05484.1 - 1.7e-50 171.8 0.1 5.2e-50 170.1 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB05484.1 - 7.8e-15 55.2 0.0 6e-14 52.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB05484.1 - 1.2e-07 31.9 0.5 9.7e-07 28.9 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EEB05484.1 - 6.9e-06 25.8 7.9 6.9e-06 25.8 7.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EEB05484.1 - 3.1e-05 23.8 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 EEB05484.1 - 0.0005 20.2 6.7 0.0005 20.2 6.7 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EEB05484.1 - 0.0021 18.0 2.6 0.0021 18.0 2.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEB05484.1 - 0.006 16.4 7.2 0.006 16.4 7.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Ribul_P_3_epim PF00834.19 EEB05485.1 - 1.1e-75 253.4 0.0 1.3e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EEB05485.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Iso_dh PF00180.20 EEB05486.1 - 6.4e-95 318.2 0.0 1.2e-94 317.4 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rabaptin PF03528.15 EEB05486.1 - 0.067 11.9 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 Rabaptin Ribosomal_S17_N PF16205.5 EEB05487.1 - 2.3e-30 104.8 0.6 4e-30 104.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EEB05487.1 - 1.9e-28 98.3 0.5 1.9e-28 98.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Rot1 PF10681.9 EEB05488.1 - 9.9e-83 276.8 3.4 1.2e-82 276.5 3.4 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal RRM_1 PF00076.22 EEB05489.2 - 1e-24 86.1 0.3 4.4e-15 55.2 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB05489.2 - 0.0021 18.1 0.1 0.0052 16.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 EEB05489.2 - 0.007 16.0 1.7 0.63 9.8 0.5 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Prefoldin PF02996.17 EEB05490.2 - 1.8e-31 108.5 2.0 1.8e-31 108.5 2.0 1.8 1 1 1 2 2 2 1 Prefoldin subunit DUF1664 PF07889.12 EEB05490.2 - 0.00092 19.2 0.2 0.45 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 EEB05490.2 - 0.0029 17.5 2.0 0.0029 17.5 2.0 2.6 1 1 1 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EEB05490.2 - 0.035 14.7 3.1 0.94 10.1 3.1 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TLE_N PF03920.15 EEB05490.2 - 0.044 13.9 0.2 0.093 12.8 0.2 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain End3 PF12761.7 EEB05490.2 - 0.051 13.7 1.3 0.24 11.5 1.3 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 YejG PF13989.6 EEB05490.2 - 0.082 13.3 0.1 0.35 11.3 0.0 1.8 1 1 0 2 2 2 0 YejG-like protein FlaC_arch PF05377.11 EEB05490.2 - 0.13 12.6 1.9 8.3 6.9 0.1 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) THOC7 PF05615.13 EEB05490.2 - 0.21 11.8 5.7 4.1 7.7 5.2 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 NPV_P10 PF05531.12 EEB05490.2 - 0.57 10.7 2.5 9.6 6.8 0.5 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PAP2_3 PF14378.6 EEB05491.1 - 4.8e-27 94.9 14.8 4.8e-27 94.9 14.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EEB05491.1 - 3.4e-08 33.3 6.0 3.4e-08 33.3 6.0 2.5 2 1 0 2 2 2 1 PAP2 superfamily IF4E PF01652.18 EEB05492.2 - 8.7e-44 149.1 0.1 1.5e-43 148.3 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_PK PF05891.12 EEB05493.1 - 1.4e-87 292.8 0.0 1.6e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EEB05493.1 - 1.1e-09 38.9 0.0 2.4e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB05493.1 - 1.7e-06 28.0 0.0 1.4e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB05493.1 - 0.00014 22.5 0.0 0.00028 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BRAP2 PF07576.12 EEB05494.1 - 2.1e-30 104.9 0.0 3.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EEB05494.1 - 1.7e-18 66.7 10.2 1.7e-18 66.7 10.2 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EEB05494.1 - 4.9e-07 30.0 9.6 4.9e-07 30.0 9.6 2.6 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB05494.1 - 4.3e-05 23.3 8.8 4.3e-05 23.3 8.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEB05494.1 - 7.7e-05 22.9 6.5 0.00029 21.0 6.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEB05494.1 - 0.00025 20.9 8.5 0.00025 20.9 8.5 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEB05494.1 - 0.00044 19.9 5.4 0.00044 19.9 5.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger CC2-LZ PF16516.5 EEB05494.1 - 0.018 15.4 21.5 0.048 14.0 8.7 3.5 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RRM_1 PF00076.22 EEB05494.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 EEB05494.1 - 0.54 10.8 7.4 1.4 9.5 0.2 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 EEB05494.1 - 0.55 10.5 21.6 0.77 10.0 3.4 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF4407 PF14362.6 EEB05494.1 - 0.74 9.1 12.6 1.3 8.4 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EEB05494.1 - 2.8 8.4 20.5 1.4 9.3 2.7 3.9 1 1 3 4 4 4 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EEB05494.1 - 3.8 7.0 11.9 6 6.3 11.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 EEB05494.1 - 3.9 7.9 27.7 0.72 10.2 22.7 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SpoIISA_toxin PF14171.6 EEB05494.1 - 4.3 7.0 8.0 6.9 6.3 8.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Prefoldin_2 PF01920.20 EEB05494.1 - 6 6.9 26.3 0.5 10.4 4.6 3.7 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 EEB05494.1 - 8.5 6.9 9.0 5.9 7.4 0.9 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CSN5_C PF18323.1 EEB05494.1 - 9.1 7.3 18.0 0.71 10.8 7.4 3.0 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain KASH_CCD PF14662.6 EEB05494.1 - 9.2 6.0 31.4 15 5.4 3.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH PHD PF00628.29 EEB05495.2 - 0.00034 20.4 10.8 0.00065 19.6 10.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EEB05495.2 - 0.0011 19.1 3.6 0.0028 17.9 3.6 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EEB05495.2 - 0.004 17.3 2.9 0.0083 16.3 2.9 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.6 EEB05495.2 - 0.054 13.1 5.4 0.1 12.2 5.4 1.5 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 EEB05496.2 - 4.3e-44 147.6 3.0 6e-09 36.4 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05496.2 - 5.6e-16 58.6 0.1 0.0078 16.5 0.0 6.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB05496.2 - 1.2e-07 30.8 0.6 0.036 12.7 0.0 3.7 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEB05496.2 - 0.00056 18.8 0.0 0.081 11.6 0.0 3.0 1 1 1 2 2 2 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EEB05496.2 - 0.00094 18.2 0.7 3.1 6.6 0.0 3.4 2 2 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain DUF1989 PF09347.10 EEB05496.2 - 0.013 15.2 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1989) Frtz PF11768.8 EEB05496.2 - 0.022 13.1 0.0 0.31 9.3 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EEB05496.2 - 0.12 11.7 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain LisH PF08513.11 EEB05496.2 - 0.14 12.1 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 LisH Cytochrom_D1 PF02239.16 EEB05496.2 - 0.17 10.4 0.0 1.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain BSD PF03909.17 EEB05497.2 - 5.9e-25 87.0 4.1 8.7e-12 44.9 0.2 3.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EEB05497.2 - 3.8e-18 65.6 0.0 7.9e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Ribosomal_S7 PF00177.21 EEB05498.1 - 1.1e-35 122.5 1.9 1.7e-35 121.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PH_10 PF15411.6 EEB05499.2 - 8.7e-34 116.4 0.1 2.1e-33 115.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EEB05499.2 - 3.9e-25 87.9 0.2 8.7e-25 86.8 0.2 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EEB05499.2 - 9.6e-24 84.6 1.4 1.4e-11 45.0 0.6 2.6 1 1 1 2 2 2 2 RhoGEF domain PB1 PF00564.24 EEB05499.2 - 5.9e-13 48.6 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 EEB05499.2 - 0.00074 20.0 0.1 0.0016 18.9 0.1 1.6 1 0 0 1 1 1 1 PH domain V_ATPase_I PF01496.19 EEB05500.2 - 4.1e-298 990.9 0.0 5e-298 990.6 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Vps51 PF08700.11 EEB05500.2 - 0.092 12.8 3.2 1.6 8.8 1.2 2.8 3 0 0 3 3 3 0 Vps51/Vps67 CorA PF01544.18 EEB05500.2 - 0.11 11.8 1.3 8 5.7 0.4 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4988 PF16378.5 EEB05500.2 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function Baculo_PEP_C PF04513.12 EEB05500.2 - 0.45 10.5 2.1 4.1 7.5 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 EEB05500.2 - 2.5 8.0 5.7 2.8 7.8 0.2 3.5 5 0 0 5 5 5 0 DASH complex subunit Dam1 RRM_1 PF00076.22 EEB05501.1 - 3.8e-27 93.9 0.3 9.2e-17 60.6 0.0 4.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB05501.1 - 3.3e-05 23.9 0.4 0.029 14.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EEB05501.1 - 0.0012 18.6 0.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM PF05172.13 EEB05501.1 - 0.0034 17.3 0.1 1.6 8.7 0.0 2.5 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EEB05501.1 - 0.15 12.1 0.1 29 4.8 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.15 EEB05501.1 - 1.7 8.6 23.4 2.3 8.2 21.8 2.1 2 1 0 2 2 2 0 Smg-4/UPF3 family Presenilin PF01080.17 EEB05501.1 - 5.3 5.7 16.1 7.4 5.2 16.1 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EEB05501.1 - 6 4.7 9.7 8.3 4.2 9.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 EEB05501.1 - 7.8 4.7 20.9 13 4.0 20.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S46 PF10459.9 EEB05501.1 - 9.3 4.7 19.2 13 4.2 19.2 1.1 1 0 0 1 1 1 0 Peptidase S46 CM_2 PF01817.21 EEB05503.1 - 0.022 15.1 0.6 0.36 11.2 0.2 2.5 2 1 0 2 2 2 0 Chorismate mutase type II DUF962 PF06127.11 EEB05504.2 - 5.9e-22 77.6 2.6 2.5e-21 75.6 2.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Acetyltransf_1 PF00583.25 EEB05504.2 - 2.6e-15 56.7 0.1 4.4e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB05504.2 - 1.4e-09 38.0 0.1 2.3e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB05504.2 - 3.6e-09 36.9 0.1 6.8e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB05504.2 - 0.0048 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH3_1 PF00018.28 EEB05505.1 - 1.5e-31 107.7 4.4 2.1e-12 46.4 0.0 5.0 4 1 0 4 4 4 4 SH3 domain SHD1 PF03983.12 EEB05505.1 - 7e-31 105.9 0.0 1.2e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 EEB05505.1 - 8e-31 105.7 4.8 1.9e-10 40.4 0.1 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EEB05505.1 - 1.6e-19 69.3 0.0 0.00012 21.7 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain Mito_carr PF00153.27 EEB05506.1 - 5.1e-73 241.1 0.3 2.7e-25 88.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB05506.1 - 0.097 11.8 0.1 9.3 5.3 0.0 3.4 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Ribosomal_S7 PF00177.21 EEB05507.1 - 1.2e-36 125.6 1.7 1.5e-36 125.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Prefoldin_2 PF01920.20 EEB05508.1 - 6.8e-22 77.4 9.1 7.8e-22 77.2 9.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit RmuC PF02646.16 EEB05508.1 - 0.0066 15.6 2.8 0.36 9.9 0.2 2.0 2 0 0 2 2 2 2 RmuC family DUF1664 PF07889.12 EEB05508.1 - 0.032 14.3 3.2 0.04 14.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 EEB05508.1 - 0.094 12.1 4.5 0.28 10.6 4.5 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4840 PF16128.5 EEB05508.1 - 0.11 12.5 0.5 0.82 9.7 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4840) PCEMA1 PF07418.11 EEB05508.1 - 0.12 11.9 4.5 0.13 11.7 4.5 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Sipho_Gp157 PF05565.11 EEB05508.1 - 0.18 11.8 6.2 0.72 9.9 2.6 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Spc24 PF08286.11 EEB05508.1 - 0.33 11.2 7.6 3.7 7.8 2.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 XRCC4 PF06632.12 EEB05508.1 - 0.33 9.8 9.4 0.033 13.0 3.7 1.8 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 YabA PF06156.13 EEB05508.1 - 0.47 11.1 6.0 2.8 8.6 1.5 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Csm1_N PF18504.1 EEB05508.1 - 1.2 9.6 10.8 2.7 8.4 3.0 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Yip1 PF04893.17 EEB05509.1 - 3.5e-12 46.4 5.9 3.5e-12 46.4 5.9 1.4 1 1 0 1 1 1 1 Yip1 domain WD40 PF00400.32 EEB05510.1 - 8.1e-11 42.3 3.7 1.5 9.8 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-CCCH PF00642.24 EEB05511.1 - 2.3e-18 65.6 21.0 2e-07 30.7 0.7 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEB05511.1 - 7.7e-14 51.2 27.9 3.7e-06 26.8 3.6 4.4 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 EEB05511.1 - 1.5e-11 44.9 20.6 2.1e-05 25.2 0.9 4.1 1 1 3 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 EEB05511.1 - 2.9e-07 30.1 20.0 3.4e-06 26.7 0.5 4.0 3 1 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EEB05511.1 - 0.097 12.9 12.5 1.2 9.3 2.9 2.9 1 1 2 3 3 3 0 Zinc-finger containing family DiSB-ORF2_chro PF16506.5 EEB05511.1 - 0.39 10.7 4.0 5.6 7.0 0.9 2.6 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses Mur_ligase_M PF08245.12 EEB05513.1 - 1.4e-07 31.7 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Prefoldin_2 PF01920.20 EEB05514.1 - 5.9e-11 42.3 5.3 2.1e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 Prefoldin subunit PRKCSH PF07915.13 EEB05515.1 - 7.5e-08 33.3 1.5 7.5e-08 33.3 1.5 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EEB05515.1 - 1.8e-05 24.5 0.1 3.5e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4988 PF16378.5 EEB05515.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function WD40 PF00400.32 EEB05516.1 - 2.4e-34 116.8 14.4 6.8e-07 29.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05516.1 - 2.2e-12 47.1 2.3 3.1e-06 27.4 0.1 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EEB05516.1 - 1.3e-10 40.6 1.2 1.3e-10 40.6 1.2 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.11 EEB05516.1 - 7.7e-06 25.9 0.0 0.18 11.7 0.0 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A NifU_N PF01592.16 EEB05517.1 - 4.9e-54 181.9 0.0 6.2e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EEB05517.1 - 0.0054 16.9 0.1 0.0097 16.1 0.1 1.3 1 0 0 1 1 1 1 TSCPD domain DUF1858 PF08984.11 EEB05517.1 - 0.053 13.7 0.1 0.14 12.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1858) Ribosomal_60s PF00428.19 EEB05517.1 - 0.06 13.9 4.0 0.11 13.1 3.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PRK PF00485.18 EEB05518.1 - 3.3e-06 27.0 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EEB05518.1 - 7.9e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EEB05518.1 - 0.00033 20.4 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEB05518.1 - 0.00043 19.6 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EEB05518.1 - 0.00087 19.5 0.1 0.007 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EEB05518.1 - 0.00095 18.4 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EEB05518.1 - 0.0011 19.4 0.1 0.0013 19.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Ploopntkinase3 PF18751.1 EEB05518.1 - 0.0028 17.6 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 MeaB PF03308.16 EEB05518.1 - 0.0055 15.7 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EEB05518.1 - 0.0057 16.9 1.1 0.013 15.8 0.3 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EEB05518.1 - 0.0059 17.0 0.2 0.016 15.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EEB05518.1 - 0.0064 15.8 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EEB05518.1 - 0.0081 16.5 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEB05518.1 - 0.0084 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein KAP_NTPase PF07693.14 EEB05518.1 - 0.01 15.1 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 EEB05518.1 - 0.012 16.2 0.1 0.064 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB05518.1 - 0.012 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EEB05518.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EEB05518.1 - 0.02 15.4 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EEB05518.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EEB05518.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EEB05518.1 - 0.033 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.9 EEB05518.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 EEB05518.1 - 0.041 14.2 0.0 0.085 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 EEB05518.1 - 0.05 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 EEB05518.1 - 0.056 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EEB05518.1 - 0.064 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 EEB05518.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC GTP_EFTU PF00009.27 EEB05518.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 EEB05518.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 1 0 NTPase DUF87 PF01935.17 EEB05518.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EEB05518.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EEB05518.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Thymidylate_kin PF02223.17 EEB05518.1 - 0.15 11.7 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 EEB05518.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1752 PF08550.10 EEB05519.1 - 6.3e-11 41.9 3.6 1.4e-10 40.8 3.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ROS_MUCR PF05443.11 EEB05520.1 - 0.096 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Sld5 PF05916.11 EEB05521.1 - 9.9e-16 58.2 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L7Ae PF01248.26 EEB05522.2 - 1.7e-23 82.1 0.6 2.8e-23 81.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EEB05522.2 - 0.0011 19.1 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 zf-HIT PF04438.16 EEB05523.1 - 3e-09 36.6 7.3 5.2e-09 35.8 7.3 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EEB05523.1 - 0.22 11.6 7.0 0.57 10.3 7.0 1.7 1 1 0 1 1 1 0 MYND finger WD40 PF00400.32 EEB05524.1 - 6.7e-12 45.7 0.1 0.011 16.5 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05524.1 - 2.8e-07 30.8 0.0 0.025 14.9 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEB05524.1 - 0.00027 20.1 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region VID27 PF08553.10 EEB05524.1 - 0.067 12.2 0.4 1.3 8.0 0.4 2.6 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain MMS1_N PF10433.9 EEB05524.1 - 0.072 11.7 0.0 0.66 8.5 0.0 2.1 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term RRM_1 PF00076.22 EEB05525.1 - 8.7e-15 54.3 0.1 1.3e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB05525.1 - 0.00039 20.0 0.0 0.00048 19.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB05525.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Elongin_A PF06881.11 EEB05526.1 - 1.7e-26 92.8 0.6 2.6e-26 92.2 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ABC_tran PF00005.27 EEB05527.2 - 2.7e-46 157.5 0.6 1.3e-22 80.8 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EEB05527.2 - 2.5e-23 81.9 8.0 2.5e-23 81.9 8.0 3.9 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 EEB05527.2 - 2.7e-14 53.7 4.3 0.0021 17.9 0.0 5.1 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEB05527.2 - 2.2e-10 40.4 0.5 0.048 13.1 0.5 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEB05527.2 - 4e-08 33.8 0.4 0.0046 17.4 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EEB05527.2 - 1.8e-07 31.1 0.8 0.0027 17.5 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EEB05527.2 - 2.2e-07 31.5 1.3 0.0049 17.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.6 EEB05527.2 - 2.8e-07 30.2 0.0 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEB05527.2 - 6.7e-07 29.7 1.0 0.02 15.2 0.1 3.4 2 2 0 2 2 2 2 AAA domain MeaB PF03308.16 EEB05527.2 - 1.2e-06 27.7 0.2 0.028 13.4 0.1 2.9 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EEB05527.2 - 6.2e-06 26.3 5.1 0.0064 16.6 0.5 3.7 3 1 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB05527.2 - 2.1e-05 24.5 0.1 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EEB05527.2 - 4.2e-05 24.0 0.0 0.067 13.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEB05527.2 - 5.5e-05 23.2 0.1 0.68 10.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EEB05527.2 - 0.00012 22.3 2.5 0.083 13.1 0.2 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EEB05527.2 - 0.00022 21.4 0.2 0.41 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EEB05527.2 - 0.00023 21.1 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 3 2 NTPase RNA_helicase PF00910.22 EEB05527.2 - 0.00028 21.3 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EEB05527.2 - 0.0015 18.3 0.0 1.7 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EEB05527.2 - 0.0016 17.8 0.1 1.7 7.8 0.0 3.5 3 1 0 3 3 3 1 KAP family P-loop domain AAA_7 PF12775.7 EEB05527.2 - 0.0022 17.5 0.0 0.51 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EEB05527.2 - 0.0036 17.2 0.1 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 EEB05527.2 - 0.0047 16.9 0.1 5 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EEB05527.2 - 0.0081 15.8 1.7 8.3 5.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.13 EEB05527.2 - 0.011 14.9 0.9 3.7 6.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.15 EEB05527.2 - 0.013 14.3 0.1 2.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.19 EEB05527.2 - 0.015 14.9 0.2 6.1 6.4 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EEB05527.2 - 0.018 15.3 0.4 5.6 7.3 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EEB05527.2 - 0.03 14.8 0.0 0.14 12.6 0.0 5.3 5 1 0 5 5 4 0 AAA domain ATP-synt_ab PF00006.25 EEB05527.2 - 0.035 13.8 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Fibin PF15819.5 EEB05527.2 - 0.039 13.7 0.4 0.039 13.7 0.4 2.0 2 0 0 2 2 2 0 Fin bud initiation factor homologue DUF87 PF01935.17 EEB05527.2 - 0.047 13.8 15.1 0.14 12.2 0.0 4.8 4 1 1 5 5 5 0 Helicase HerA, central domain AAA_15 PF13175.6 EEB05527.2 - 0.049 13.3 15.6 0.69 9.6 0.0 4.9 5 1 1 6 6 6 0 AAA ATPase domain NB-ARC PF00931.22 EEB05527.2 - 0.061 12.5 0.9 5 6.2 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Rad17 PF03215.15 EEB05527.2 - 0.062 13.2 0.1 13 5.7 0.0 3.2 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_25 PF13481.6 EEB05527.2 - 0.076 12.6 0.4 22 4.6 0.6 3.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EEB05527.2 - 0.086 13.1 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EEB05527.2 - 0.12 12.2 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EEB05527.2 - 0.16 12.1 0.0 0.16 12.1 0.0 3.4 4 2 0 4 4 2 0 Dynamin family AAA_11 PF13086.6 EEB05527.2 - 4.8 6.9 9.7 41 3.8 0.0 4.0 4 0 0 4 4 4 0 AAA domain FlxA PF14282.6 EEB05527.2 - 5.5 7.0 9.1 0.9 9.6 4.6 2.0 2 0 0 2 2 1 0 FlxA-like protein T3SSipB PF16535.5 EEB05527.2 - 9.5 6.7 12.2 0.47 10.9 2.8 2.8 3 0 0 3 3 2 0 Type III cell invasion protein SipB ATP_sub_h PF10775.9 EEB05528.1 - 1.3e-16 60.3 0.1 2e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Mito_carr PF00153.27 EEB05529.1 - 7.6e-37 125.1 3.1 2.1e-13 50.0 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein S4 PF01479.25 EEB05530.1 - 2.1e-11 43.4 1.4 2.1e-11 43.4 1.4 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EEB05530.1 - 6.8e-07 30.1 0.3 1.3e-06 29.2 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PWWP PF00855.17 EEB05531.2 - 5.7e-17 61.9 0.7 2.7e-16 59.7 0.0 2.6 2 0 0 2 2 2 1 PWWP domain UCH PF00443.29 EEB05532.1 - 3.9e-57 193.7 0.5 5.9e-57 193.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB05532.1 - 2.8e-23 83.0 0.6 1.9e-22 80.3 0.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EEB05532.1 - 0.00038 20.0 1.2 0.68 9.4 0.3 3.1 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Mito_carr PF00153.27 EEB05533.2 - 9.1e-39 131.3 8.7 2.7e-15 56.0 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Topoisom_I_N PF02919.15 EEB05534.2 - 9.8e-101 335.7 2.6 9.8e-101 335.7 2.6 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EEB05534.2 - 2.1e-80 269.3 0.2 2.1e-80 269.3 0.2 3.4 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EEB05534.2 - 3.4e-28 97.4 0.8 3.4e-28 97.4 0.8 2.9 2 0 0 2 2 2 1 C-terminal topoisomerase domain Sec1 PF00995.23 EEB05535.1 - 1.6e-90 305.0 0.0 1.8e-90 304.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.32 EEB05536.1 - 1.2e-11 45.0 6.6 0.00011 22.9 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.11 EEB05536.1 - 4.2e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EEB05536.1 - 9.3e-05 22.7 0.0 1.3 9.4 0.0 3.7 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NUC PF18510.1 EEB05536.1 - 0.16 12.4 0.1 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 Nuclease domain RhoGAP PF00620.27 EEB05537.1 - 1.7e-35 122.1 0.7 6.2e-35 120.3 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EEB05537.1 - 2.1e-21 75.9 42.9 5.7e-12 45.7 6.4 4.7 4 0 0 4 4 4 3 LIM domain zf-RING_2 PF13639.6 EEB05538.1 - 1.2e-16 60.8 14.1 1.2e-13 51.2 3.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EEB05538.1 - 4.4e-09 36.2 7.6 1.4e-06 28.2 1.2 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEB05538.1 - 1.8e-08 34.1 4.0 1.8e-08 34.1 4.0 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB05538.1 - 2.4e-08 33.8 12.7 6e-06 26.1 2.2 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEB05538.1 - 5e-08 32.7 1.5 5e-08 32.7 1.5 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB05538.1 - 3.7e-07 29.9 11.4 7e-06 25.8 2.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEB05538.1 - 1e-06 28.5 15.3 0.00017 21.4 6.2 3.4 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EEB05538.1 - 2.5e-06 27.6 16.2 5.3e-06 26.6 7.3 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EEB05538.1 - 4.9e-05 23.0 3.0 0.0014 18.4 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EEB05538.1 - 0.00013 21.9 5.5 0.00016 21.6 0.6 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EEB05538.1 - 0.074 13.2 8.9 0.18 12.0 2.8 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EEB05538.1 - 0.11 12.3 12.3 0.095 12.5 4.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EEB05538.1 - 0.22 11.7 9.6 2.9 8.1 2.7 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EEB05538.1 - 0.62 10.2 4.4 0.3 11.3 0.5 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 EEB05538.1 - 0.86 9.3 10.4 0.18 11.4 2.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EEB05538.1 - 3.5 7.8 8.1 1.6 8.9 2.4 2.5 2 0 0 2 2 2 0 RING-variant domain DUF846 PF05832.12 EEB05539.1 - 3.2e-50 169.8 12.0 3.8e-50 169.5 12.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 EEB05539.1 - 0.0019 18.5 8.6 0.0078 16.5 1.3 2.1 2 0 0 2 2 2 2 YwiC-like protein DUF2207 PF09972.9 EEB05539.1 - 7.2 5.3 5.5 24 3.6 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Prenyltransf PF01255.19 EEB05540.1 - 2.6e-07 30.4 0.0 5.5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 EEB05540.1 - 0.0087 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) zf-PARP PF00645.18 EEB05541.2 - 1.9e-21 76.7 0.1 3.7e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FXMRP1_C_core PF12235.8 EEB05541.2 - 0.0098 16.5 2.3 0.018 15.7 2.3 1.3 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal Met_gamma_lyase PF06838.11 EEB05541.2 - 0.066 11.7 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DTHCT PF08070.11 EEB05541.2 - 0.12 13.1 7.8 0.46 11.3 7.8 2.0 1 1 1 2 2 2 0 DTHCT (NUC029) region Mucin-like PF16058.5 EEB05542.1 - 0.013 15.6 2.8 0.017 15.2 2.8 1.2 1 0 0 1 1 1 0 Mucin-like Longin PF13774.6 EEB05543.1 - 1.3e-26 92.4 0.0 2.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EEB05543.1 - 6e-15 54.8 0.0 9.6e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Phosducin PF02114.16 EEB05544.1 - 6e-24 84.4 0.2 7.3e-24 84.1 0.2 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EEB05544.1 - 9.9e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Bin3 PF06859.12 EEB05545.2 - 7.7e-23 81.2 0.1 1.6e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 EEB05545.2 - 3.8e-14 52.8 0.0 3.1e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEB05545.2 - 2.2e-12 47.5 0.0 1.9e-06 28.5 0.0 2.2 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEB05545.2 - 1.2e-10 41.5 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB05545.2 - 2e-09 38.1 0.0 0.00097 19.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EEB05545.2 - 2.7e-09 37.6 0.0 0.0019 18.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.7 EEB05545.2 - 6.9e-06 26.1 0.0 9.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB05545.2 - 4.4e-05 23.0 0.0 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EEB05545.2 - 0.00051 19.4 0.0 0.5 9.6 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase MTS PF05175.14 EEB05545.2 - 0.00092 18.8 0.0 0.017 14.6 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EEB05545.2 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 EEB05545.2 - 0.0075 15.2 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 EEB05545.2 - 0.035 13.7 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) RrnaAD PF00398.20 EEB05545.2 - 0.054 12.6 0.0 0.12 11.4 0.0 1.6 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EEB05545.2 - 0.061 13.1 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EEB05545.2 - 0.085 13.0 0.0 0.73 9.9 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EEB05545.2 - 0.11 11.9 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase SAC3_GANP PF03399.16 EEB05546.1 - 7.7e-26 91.2 8.2 5.9e-24 85.0 8.2 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EEB05546.1 - 2.2e-08 34.2 0.9 2.2e-08 34.2 0.9 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family COX5A PF02284.16 EEB05546.1 - 0.0051 16.8 1.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va zinc_ribbon_16 PF17034.5 EEB05547.2 - 3.7e-56 188.7 19.3 7.1e-56 187.8 19.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Nup84_Nup100 PF04121.13 EEB05547.2 - 0.035 12.2 0.0 0.052 11.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Efg1 PF10153.9 EEB05548.1 - 3.1e-31 108.1 15.0 3.1e-31 108.1 15.0 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 RbsD_FucU PF05025.13 EEB05548.1 - 0.18 12.3 4.4 0.074 13.5 1.2 1.9 1 1 1 2 2 2 0 RbsD / FucU transport protein family ING PF12998.7 EEB05548.1 - 0.26 11.9 7.2 1.4 9.5 7.2 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding RRM_1 PF00076.22 EEB05549.2 - 2e-07 30.7 0.0 5.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 EEB05550.2 - 6.9e-87 292.1 8.6 1e-86 291.5 8.6 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop10p PF04135.12 EEB05551.1 - 9.9e-24 83.1 2.3 1.2e-23 82.9 2.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Hid1 PF12722.7 EEB05552.1 - 6.2e-221 735.8 21.4 1.3e-220 734.7 21.4 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EEB05552.1 - 3.5e-54 184.3 14.7 3.9e-54 184.1 14.7 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TOM13 PF08219.11 EEB05553.1 - 1.5e-11 44.1 0.1 1.7e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 MPP6 PF10175.9 EEB05554.1 - 0.019 15.5 3.4 0.49 10.9 0.5 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 SPT6_acidic PF14632.6 EEB05554.1 - 0.084 13.5 10.2 1.2 9.8 0.5 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SRP72 PF08492.12 EEB05554.1 - 0.72 10.3 13.3 2.1 8.9 3.9 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain WD40 PF00400.32 EEB05555.1 - 1.7e-30 104.6 12.9 1.6e-08 35.1 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05555.1 - 1.6e-09 38.0 0.7 1.6 9.1 0.0 5.6 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEB05555.1 - 6e-07 29.1 0.9 0.0045 16.3 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 EEB05555.1 - 6.6e-05 22.9 0.1 0.45 10.4 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EEB05555.1 - 0.00016 21.7 0.1 0.39 10.8 0.0 3.9 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 EEB05555.1 - 0.0019 17.7 0.1 0.012 15.1 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5046) RAB3GAP2_N PF14655.6 EEB05555.1 - 0.011 15.1 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 EEB05555.1 - 0.032 12.6 0.2 0.13 10.5 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RVT_1 PF00078.27 EEB05555.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 EEB05556.1 - 6.5e-40 134.4 16.0 8.1e-08 32.8 0.1 12.5 13 0 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05556.1 - 2e-24 85.7 0.0 0.012 15.8 0.0 9.9 3 2 7 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EEB05556.1 - 5.3e-21 74.9 0.1 8.5e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EEB05556.1 - 4.5e-09 35.7 0.1 0.99 8.3 0.0 6.6 5 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEB05556.1 - 1.7e-06 28.1 0.0 0.026 14.4 0.0 4.8 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEB05556.1 - 7e-05 21.7 3.9 0.046 12.4 0.0 4.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EEB05556.1 - 8.7e-05 22.0 0.5 2.7 7.2 0.1 4.3 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 EEB05556.1 - 0.0071 16.1 0.2 0.43 10.3 0.0 2.7 2 1 0 2 2 2 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.14 EEB05556.1 - 0.018 14.1 0.0 2.4 7.1 0.0 3.3 3 1 2 5 5 5 0 Coatomer WD associated region ELYS-bb PF16687.5 EEB05556.1 - 0.025 13.2 0.3 0.29 9.7 0.0 2.8 3 1 1 4 4 4 0 beta-propeller of ELYS nucleoporin PQQ_3 PF13570.6 EEB05556.1 - 0.04 14.4 3.6 9.4 6.9 0.0 5.1 6 0 0 6 6 5 0 PQQ-like domain Cytochrom_D1 PF02239.16 EEB05556.1 - 0.045 12.3 0.2 0.66 8.4 0.0 2.9 3 1 1 4 4 4 0 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 EEB05556.1 - 0.072 12.3 0.0 15 4.7 0.0 2.9 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus USP7_ICP0_bdg PF12436.8 EEB05557.1 - 3.1e-60 203.5 5.5 1.1e-59 201.6 3.5 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EEB05557.1 - 7.2e-53 179.3 10.3 1.5e-51 175.0 0.2 3.3 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 EEB05557.1 - 3.4e-49 167.7 0.5 3.4e-49 167.7 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB05557.1 - 1.1e-22 81.1 0.0 3.5e-22 79.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EEB05557.1 - 0.0011 19.1 0.0 0.084 13.0 0.0 3.2 1 1 0 1 1 1 1 MATH domain ubiquitin PF00240.23 EEB05557.1 - 0.01 15.5 0.0 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin family SGS PF05002.15 EEB05558.2 - 4.9e-34 116.3 1.1 4.9e-34 116.3 1.1 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EEB05558.2 - 4.9e-13 49.9 0.6 1.2e-12 48.6 0.1 2.0 2 0 0 2 2 2 1 CS domain DUF2057 PF09829.9 EEB05558.2 - 0.0057 16.8 2.1 0.0057 16.8 2.1 2.5 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) TPR_9 PF13371.6 EEB05558.2 - 0.011 15.9 0.3 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SYF2 PF08231.12 EEB05558.2 - 0.43 11.0 6.0 3.5 8.0 0.5 2.4 2 0 0 2 2 2 0 SYF2 splicing factor IBB PF01749.20 EEB05558.2 - 1.3 9.5 7.0 0.94 10.0 0.8 2.4 2 0 0 2 2 2 0 Importin beta binding domain DUF4404 PF14357.6 EEB05558.2 - 2.6 8.8 7.0 18 6.0 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Adeno_E3_CR2 PF02439.15 EEB05559.1 - 0.0055 16.4 2.7 0.011 15.5 2.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 FAM163 PF15069.6 EEB05559.1 - 0.018 15.5 0.0 0.056 13.9 0.0 1.9 2 0 0 2 2 2 0 FAM163 family RIFIN PF02009.16 EEB05559.1 - 0.087 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Rifin MRVI1 PF05781.12 EEB05559.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 MRVI1 protein PRELI PF04707.14 EEB05560.1 - 2.4e-48 163.9 1.4 2.9e-48 163.7 1.4 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3449 PF11931.8 EEB05561.1 - 2.7e-72 242.4 0.1 2.7e-72 242.4 0.1 2.5 2 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EEB05561.1 - 2e-25 89.1 4.5 6.5e-25 87.5 4.5 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EEB05561.1 - 5.1e-10 39.1 1.9 7.4e-10 38.5 0.3 2.1 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EEB05561.1 - 6.3e-09 35.9 3.6 6.3e-09 35.9 3.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEB05561.1 - 2.2e-07 31.0 3.7 4.7e-06 26.8 1.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EEB05561.1 - 0.00017 21.8 4.6 0.00095 19.5 3.0 2.6 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EEB05561.1 - 0.018 15.9 3.1 2.3 9.3 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 EEB05561.1 - 0.06 13.1 0.8 0.06 13.1 0.8 2.4 3 0 0 3 3 3 0 U1 zinc finger zf-Di19 PF05605.12 EEB05561.1 - 0.07 13.4 1.3 0.34 11.2 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.11 EEB05561.1 - 0.091 13.2 3.2 0.29 11.5 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4512 PF14975.6 EEB05561.1 - 0.65 10.8 0.1 0.65 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) zf-DBF PF07535.12 EEB05561.1 - 0.7 10.1 10.7 0.35 11.0 0.4 4.3 4 0 0 4 4 4 0 DBF zinc finger Presenilin PF01080.17 EEB05561.1 - 2 7.1 3.4 3.1 6.5 3.4 1.2 1 0 0 1 1 1 0 Presenilin COG2 PF06148.11 EEB05562.1 - 4.5e-12 46.2 6.5 7.3e-12 45.5 6.5 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EEB05562.1 - 7.3e-07 29.2 0.5 7.3e-07 29.2 0.5 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.13 EEB05562.1 - 1.3e-05 24.0 2.5 1.6e-05 23.7 2.5 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dynamitin PF04912.14 EEB05562.1 - 0.00019 20.9 4.0 0.00023 20.6 4.0 1.1 1 0 0 1 1 1 1 Dynamitin Dor1 PF04124.12 EEB05562.1 - 0.0028 16.4 4.4 0.0034 16.1 4.4 1.2 1 0 0 1 1 1 1 Dor1-like family BRE1 PF08647.11 EEB05562.1 - 0.023 14.7 11.2 0.051 13.6 11.2 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 EEB05562.1 - 0.03 13.9 3.3 0.033 13.8 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRS4 PF10422.9 EEB05562.1 - 0.048 13.2 5.8 0.037 13.6 3.2 1.7 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 HigB-like_toxin PF05015.13 EEB05562.1 - 0.057 13.8 3.5 3.4 8.1 2.1 2.3 1 1 1 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB DUF16 PF01519.16 EEB05562.1 - 0.07 13.6 4.0 0.12 12.9 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4375 PF14300.6 EEB05562.1 - 0.093 13.0 0.2 0.093 13.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF4407 PF14362.6 EEB05562.1 - 0.1 11.9 2.6 0.14 11.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EEB05562.1 - 0.11 11.1 3.5 0.13 10.8 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 EEB05562.1 - 0.6 10.9 6.2 1.5 9.6 6.2 1.8 1 1 0 1 1 1 0 Occludin homology domain Tex_N PF09371.10 EEB05562.1 - 1.3 8.6 8.2 9 5.9 7.8 1.9 1 1 0 1 1 1 0 Tex-like protein N-terminal domain ZapB PF06005.12 EEB05562.1 - 7.2 7.1 18.1 1.1 9.8 13.4 2.2 2 1 0 2 2 1 0 Cell division protein ZapB DivIC PF04977.15 EEB05562.1 - 7.9 6.3 8.7 0.56 10.0 1.7 2.3 1 1 1 2 2 2 0 Septum formation initiator IKI3 PF04762.12 EEB05563.1 - 1.5e-283 943.2 0.0 2e-283 942.8 0.0 1.2 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EEB05563.1 - 2.8e-05 24.3 0.1 1.5 9.2 0.0 5.1 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB05563.1 - 0.0085 16.0 0.1 9.1 6.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 EEB05563.1 - 0.026 14.4 6.5 0.25 11.2 0.1 3.4 1 1 2 3 3 3 0 Region in Clathrin and VPS Vps39_1 PF10366.9 EEB05563.1 - 0.12 12.7 0.9 0.5 10.7 0.9 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Snapin_Pallidin PF14712.6 EEB05563.1 - 0.26 11.7 2.4 4 7.9 0.1 3.1 3 0 0 3 3 3 0 Snapin/Pallidin polyprenyl_synt PF00348.17 EEB05564.1 - 1.2e-77 260.4 0.1 1.5e-77 260.1 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Hist_deacetyl PF00850.19 EEB05565.1 - 6.9e-86 288.5 0.0 9.3e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 EEB05565.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 NIL domain PALP PF00291.25 EEB05566.1 - 7.5e-72 242.2 0.2 9.1e-72 241.9 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.29 EEB05567.1 - 2.5e-44 151.1 0.1 4.5e-44 150.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB05567.1 - 8.3e-23 80.9 0.0 7e-22 77.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEB05567.1 - 3.5e-20 72.0 0.1 8e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEB05567.1 - 2.5e-08 34.1 0.0 6.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIID_30kDa PF03540.13 EEB05568.1 - 2.1e-22 78.8 0.1 3.2e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EEB05568.1 - 0.053 14.1 2.6 0.28 11.7 0.1 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Bromo_TP PF07524.13 EEB05568.1 - 0.19 11.8 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Bromodomain associated Ago_N_1 PF18351.1 EEB05569.1 - 0.15 12.5 0.0 0.5 10.8 0.0 1.8 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain DUF2457 PF10446.9 EEB05569.1 - 0.42 9.7 5.1 0.6 9.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF775 PF05603.12 EEB05570.1 - 5e-61 205.7 0.1 6.2e-61 205.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RTA1 PF04479.13 EEB05571.1 - 1.3e-61 207.9 4.4 1.6e-61 207.5 4.4 1.1 1 0 0 1 1 1 1 RTA1 like protein FIST PF08495.10 EEB05571.1 - 0.12 12.4 1.0 0.31 11.0 1.0 1.6 1 1 0 1 1 1 0 FIST N domain RTA1 PF04479.13 EEB05572.1 - 3.6e-32 111.7 3.6 6.2e-16 58.6 0.5 2.3 1 1 1 2 2 2 2 RTA1 like protein BLM10_mid PF16507.5 EEB05573.1 - 2.1e-133 445.7 4.6 2e-132 442.5 1.0 2.3 2 0 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EEB05573.1 - 1.2e-10 41.1 0.0 1.4e-09 37.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 EEB05573.1 - 1e-05 25.8 0.5 0.69 10.3 0.1 5.3 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 EEB05573.1 - 0.017 15.2 3.6 0.19 11.8 0.2 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEB05573.1 - 0.048 13.7 1.3 1.3 9.1 0.1 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEB05573.1 - 0.2 12.0 6.9 0.52 10.7 0.1 5.1 6 0 0 6 6 6 0 HEAT repeat IGPD PF00475.18 EEB05574.1 - 1.1e-57 194.3 0.2 1.6e-57 193.9 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase adh_short PF00106.25 EEB05575.2 - 3.5e-27 95.2 1.1 8e-21 74.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEB05575.2 - 5.4e-22 78.5 1.8 6.6e-19 68.4 0.3 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB05575.2 - 1.4e-09 38.1 5.9 2.1e-08 34.3 5.9 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEB05575.2 - 1.4e-08 34.5 1.0 9.3e-08 31.8 1.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEB05575.2 - 3.5e-05 23.1 0.4 0.0091 15.2 0.2 2.3 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EEB05575.2 - 0.00014 21.1 0.8 0.0074 15.4 0.6 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EEB05575.2 - 0.00054 19.1 1.3 0.039 13.0 1.3 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEB05575.2 - 0.00065 19.2 0.2 0.29 10.5 0.2 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEB05575.2 - 0.03 13.9 0.4 0.044 13.3 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_43 PF03360.16 EEB05576.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 43 DUF2433 PF10360.9 EEB05577.1 - 3.1e-33 114.5 0.2 1.1e-32 112.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EEB05577.1 - 0.00016 22.2 0.0 0.00043 20.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEB05577.1 - 0.016 15.4 0.0 0.16 12.2 0.0 2.4 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain SWI-SNF_Ssr4 PF08549.10 EEB05577.1 - 2 6.9 17.3 3.3 6.2 17.3 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PRMT5 PF05185.16 EEB05578.1 - 5.5e-64 215.2 0.0 8.8e-64 214.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EEB05578.1 - 6.2e-62 209.1 0.0 9e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EEB05578.1 - 3.1e-56 190.0 1.2 4.7e-56 189.4 1.2 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 EEB05579.1 - 7.6e-23 80.7 0.1 2.8e-22 78.9 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEB05579.1 - 4.2e-21 75.3 0.0 8.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEB05579.1 - 3.4e-12 46.7 0.0 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB05579.1 - 4.2e-08 33.2 0.1 8.5e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB05579.1 - 3.8e-05 24.0 0.0 0.00012 22.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB05579.1 - 0.0094 16.3 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EEB05579.1 - 0.01 15.5 0.4 0.065 12.9 0.1 2.3 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EEB05579.1 - 0.017 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EEB05579.1 - 0.044 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EEB05579.1 - 0.054 13.5 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EEB05579.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EEB05579.1 - 0.074 12.3 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EEB05579.1 - 0.09 12.3 0.0 0.3 10.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EEB05579.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_33 PF13671.6 EEB05579.1 - 0.13 12.4 0.7 13 6.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain Glyco_transf_15 PF01793.16 EEB05580.1 - 5.8e-112 374.1 5.4 7.2e-112 373.8 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.12 EEB05580.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) ABC_tran PF00005.27 EEB05581.1 - 2.9e-46 157.4 0.0 2.8e-23 83.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EEB05581.1 - 4.9e-19 68.1 3.9 4.9e-19 68.1 3.9 3.0 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 EEB05581.1 - 4.9e-16 59.4 7.5 0.00071 19.5 0.2 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEB05581.1 - 5.1e-09 35.9 2.4 0.66 9.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEB05581.1 - 2.2e-08 33.7 0.3 0.0063 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EEB05581.1 - 2.3e-08 34.8 6.8 0.0047 17.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 EEB05581.1 - 1.4e-06 28.3 1.9 0.00081 19.5 0.2 3.4 2 1 1 3 3 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB05581.1 - 2.8e-06 27.3 0.9 0.0095 15.9 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 EEB05581.1 - 1.1e-05 25.8 0.0 0.056 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEB05581.1 - 1.3e-05 25.7 0.0 0.26 11.7 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EEB05581.1 - 1.6e-05 24.4 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_15 PF13175.6 EEB05581.1 - 4e-05 23.5 9.4 0.023 14.4 0.1 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 EEB05581.1 - 6.9e-05 23.4 0.3 0.68 10.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 EEB05581.1 - 7.3e-05 22.7 0.6 0.36 10.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 EEB05581.1 - 0.00011 22.0 0.7 1 9.1 0.1 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EEB05581.1 - 0.00022 21.6 0.6 2.1 8.8 0.0 3.6 4 0 0 4 4 4 2 RNA helicase AAA_33 PF13671.6 EEB05581.1 - 0.00037 20.7 0.1 0.78 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EEB05581.1 - 0.00038 20.5 0.2 2.9 7.9 0.0 4.2 4 1 0 4 4 4 1 AAA domain AAA_22 PF13401.6 EEB05581.1 - 0.0004 20.7 0.0 1.4 9.2 0.0 3.1 2 1 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 EEB05581.1 - 0.00047 20.3 11.1 0.15 12.1 0.2 4.3 2 1 1 3 3 3 2 Dynamin family DUF87 PF01935.17 EEB05581.1 - 0.0006 20.0 2.9 0.35 10.9 0.1 3.5 2 1 1 3 3 3 1 Helicase HerA, central domain AAA_30 PF13604.6 EEB05581.1 - 0.00089 19.0 0.3 0.4 10.4 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 EEB05581.1 - 0.0017 18.8 1.3 3.3 8.1 0.0 3.9 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EEB05581.1 - 0.0026 17.4 0.4 3.5 7.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain MeaB PF03308.16 EEB05581.1 - 0.0066 15.5 0.0 1.8 7.5 0.0 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 EEB05581.1 - 0.0087 15.7 0.1 7.3 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF2730 PF10805.8 EEB05581.1 - 0.0088 16.1 0.1 0.028 14.5 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Pox_A32 PF04665.12 EEB05581.1 - 0.0095 15.4 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_5 PF07728.14 EEB05581.1 - 0.01 15.8 0.7 5.6 7.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EEB05581.1 - 0.012 14.8 0.1 1.5 8.0 0.0 2.8 3 1 0 3 3 2 0 NB-ARC domain FeoB_N PF02421.18 EEB05581.1 - 0.015 14.9 0.0 0.095 12.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 EEB05581.1 - 0.027 13.8 0.0 5 6.3 0.0 2.6 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 EEB05581.1 - 0.032 13.9 0.0 1.3 8.6 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 EEB05581.1 - 0.033 13.7 0.2 3.2 7.2 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Roc PF08477.13 EEB05581.1 - 0.058 13.6 0.0 10 6.3 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mt_ATP-synt_D PF05873.12 EEB05581.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DAP3 PF10236.9 EEB05581.1 - 0.13 11.4 2.1 13 4.8 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 EEB05581.1 - 0.25 11.8 4.4 0.65 10.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain Metallophos PF00149.28 EEB05582.1 - 2.1e-35 123.1 0.3 3.2e-35 122.5 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EEB05582.1 - 0.0026 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EEB05582.1 - 0.0056 17.1 0.1 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Rieske PF00355.26 EEB05583.1 - 4.9e-13 48.8 0.1 8e-13 48.1 0.1 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EEB05583.1 - 1.1e-10 41.9 2.1 2.6e-10 40.6 2.1 1.6 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Fea1 PF07692.11 EEB05583.1 - 0.1 11.6 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein DUF3807 PF12720.7 EEB05584.1 - 7.2e-14 52.5 3.5 3.4e-13 50.3 3.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) GEMIN8 PF15348.6 EEB05584.1 - 0.011 16.1 1.5 0.015 15.6 1.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Pro_isomerase PF00160.21 EEB05585.1 - 1.7e-39 135.6 0.0 3.2e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fzo_mitofusin PF04799.13 EEB05585.1 - 0.0024 17.4 2.7 0.0042 16.7 2.7 1.3 1 0 0 1 1 1 1 fzo-like conserved region FapA PF03961.13 EEB05585.1 - 0.18 10.4 4.8 0.29 9.7 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 EEB05585.1 - 0.74 9.0 4.0 1.4 8.1 4.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein Pho88 PF10032.9 EEB05586.1 - 9.2e-57 191.2 0.2 1.1e-56 191.0 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.21 EEB05587.1 - 6e-71 238.6 0.0 8.1e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EEB05587.1 - 4.4e-11 43.2 7.6 5.2e-07 29.9 0.1 3.2 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EEB05587.1 - 6.3e-08 33.1 0.0 3.6e-07 30.7 0.0 2.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EEB05587.1 - 0.00092 19.6 0.0 0.0079 16.6 0.0 2.5 1 1 0 1 1 1 1 Putative NAD(P)-binding SRA1 PF07304.11 EEB05587.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Shikimate_DH PF01488.20 EEB05587.1 - 0.058 13.4 0.9 0.19 11.8 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ZapB PF06005.12 EEB05587.1 - 0.096 13.1 0.2 0.096 13.1 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Med21 PF11221.8 EEB05587.1 - 0.15 12.3 3.2 0.22 11.7 0.2 2.3 2 0 0 2 2 2 0 Subunit 21 of Mediator complex CobA_CobO_BtuR PF02572.15 EEB05587.1 - 0.21 11.9 0.3 0.63 10.3 0.1 1.8 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DivIC PF04977.15 EEB05587.1 - 7.7 6.4 7.2 0.38 10.6 1.2 2.0 2 0 0 2 2 2 0 Septum formation initiator PFK PF00365.20 EEB05588.1 - 3.2e-187 620.6 1.2 1.4e-105 352.7 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 EEB05588.1 - 6.1e-07 29.8 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 EEB05588.1 - 0.081 12.5 0.7 1.1 8.9 0.1 2.9 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Sad1_UNC PF07738.13 EEB05589.2 - 1.4e-32 112.5 0.0 2.4e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1664 PF07889.12 EEB05589.2 - 0.0054 16.8 3.5 0.0054 16.8 3.5 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Gluconate_2-dh3 PF13618.6 EEB05589.2 - 0.23 11.7 0.9 25 5.1 0.2 3.0 3 0 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 Baculo_PEP_C PF04513.12 EEB05589.2 - 8.5 6.4 13.6 4.2 7.4 2.7 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_pol_delta_4 PF04081.13 EEB05590.1 - 2.2e-41 141.3 1.0 2.5e-41 141.1 1.0 1.0 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cpn60_TCP1 PF00118.24 EEB05591.1 - 8.7e-152 506.2 13.3 9.9e-152 506.0 13.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EEB05591.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Telomere recombination Pkinase PF00069.25 EEB05592.1 - 3.2e-60 203.7 0.0 6.8e-60 202.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05592.1 - 1.1e-37 129.8 0.0 6.4e-36 124.0 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 EEB05592.1 - 1.6e-20 72.7 32.3 2.3e-11 43.4 13.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EEB05592.1 - 1.6e-20 73.0 18.5 3.2e-11 43.2 4.7 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EEB05592.1 - 9.1e-11 42.3 0.2 3.8e-10 40.3 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEB05592.1 - 3.6e-05 23.2 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 EEB05592.1 - 4.5e-05 23.7 0.2 9.2e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 C2 domain SMYLE_N PF18615.1 EEB05592.1 - 0.01 15.5 0.6 0.01 15.5 0.6 1.8 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Haspin_kinase PF12330.8 EEB05592.1 - 0.011 14.8 0.0 0.025 13.5 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Uds1 PF15456.6 EEB05592.1 - 0.22 11.7 8.0 0.34 11.1 1.0 2.9 2 0 0 2 2 2 0 Up-regulated During Septation DUF1359 PF07097.11 EEB05592.1 - 0.64 10.3 4.4 1.3 9.3 0.5 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF1359) PHD PF00628.29 EEB05592.1 - 4.6 7.2 25.2 0.15 11.9 8.8 2.6 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 EEB05592.1 - 9.3 6.7 22.5 15 6.0 9.3 2.6 2 0 0 2 2 2 0 C1 domain HORMA PF02301.18 EEB05593.1 - 0.025 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 HORMA domain Mito_carr PF00153.27 EEB05594.1 - 2.2e-71 235.8 1.7 6.7e-23 80.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PIN PF01850.21 EEB05594.1 - 0.14 12.6 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 PIN domain Cyclin_N PF00134.23 EEB05595.1 - 2.8e-12 46.5 0.1 4.2e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EEB05595.1 - 0.065 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF4306 PF14154.6 EEB05595.1 - 0.12 12.5 0.1 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) Thioredoxin PF00085.20 EEB05596.2 - 2.8e-27 94.7 0.0 3.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEB05596.2 - 2.1e-07 31.3 0.2 1.2e-06 28.9 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEB05596.2 - 2.7e-07 30.8 0.1 6.3e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EEB05596.2 - 0.00043 20.0 0.3 0.091 12.5 0.1 2.1 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 EEB05596.2 - 0.00053 19.4 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Phosducin PF02114.16 EEB05596.2 - 0.00093 18.2 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.6 EEB05596.2 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EEB05596.2 - 0.0035 17.1 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EEB05596.2 - 0.0048 16.8 0.1 0.053 13.4 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.11 EEB05596.2 - 0.0052 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 EEB05596.2 - 0.0055 16.5 0.0 0.0065 16.3 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Glutaredoxin PF00462.24 EEB05596.2 - 0.006 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 EEB05596.2 - 0.013 15.3 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.14 EEB05596.2 - 0.099 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) ubiquitin PF00240.23 EEB05597.1 - 1.1e-26 92.3 0.1 1.2e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEB05597.1 - 1.9e-14 53.2 0.1 2.1e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB05597.1 - 7.4e-05 23.1 0.0 0.00014 22.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB05597.1 - 0.00012 21.9 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DEAD PF00270.29 EEB05598.2 - 1.3e-40 139.0 0.4 2.6e-40 138.1 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB05598.2 - 2e-22 79.6 0.0 7.4e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEB05598.2 - 1.3e-21 76.6 0.6 2.7e-21 75.6 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEB05598.2 - 1.4e-07 31.7 1.1 3e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEB05598.2 - 0.015 14.6 1.5 0.015 14.5 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EEB05598.2 - 0.037 14.3 0.1 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain FAM76 PF16046.5 EEB05598.2 - 6.6 6.0 14.8 6.2 6.1 13.0 1.8 2 0 0 2 2 2 0 FAM76 protein DUF3245 PF11595.8 EEB05599.2 - 2.4e-12 47.5 16.2 2.4e-12 47.5 16.2 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) Sporozoite_P67 PF05642.11 EEB05599.2 - 0.0086 14.2 3.9 0.012 13.7 3.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen G-patch_2 PF12656.7 EEB05599.2 - 0.026 14.6 0.1 0.026 14.6 0.1 2.0 2 0 0 2 2 2 0 G-patch domain NOP19 PF10863.8 EEB05599.2 - 0.096 12.5 8.9 0.018 14.9 3.4 2.5 1 1 0 2 2 2 0 Nucleolar protein 19 Tub_N PF16322.5 EEB05599.2 - 0.24 11.8 12.8 0.38 11.1 12.8 1.3 1 1 0 1 1 1 0 Tubby N-terminal FAM176 PF14851.6 EEB05599.2 - 0.68 9.6 5.2 1.7 8.3 5.2 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 EEB05599.2 - 0.7 10.3 8.1 0.13 12.6 4.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mcl1_mid PF12341.8 EEB05600.1 - 4.6e-98 328.2 0.0 8e-96 320.9 0.0 3.0 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EEB05600.1 - 2.3e-17 63.0 14.9 1.1e-06 29.2 0.6 7.4 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05600.1 - 2.4e-16 59.8 1.6 0.00036 20.8 0.1 6.3 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EEB05600.1 - 7.9e-05 23.0 0.2 4.8 7.8 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain Cytochrom_D1 PF02239.16 EEB05600.1 - 0.00092 17.8 1.4 0.84 8.1 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EEB05600.1 - 0.00092 18.4 0.3 0.05 12.7 0.1 2.3 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 EEB05600.1 - 0.0015 18.4 0.2 0.85 9.5 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EEB05600.1 - 0.0029 16.6 0.3 7.3 5.4 0.0 3.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EEB05600.1 - 0.011 15.5 0.5 1.5 8.5 0.2 3.0 3 0 0 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.12 EEB05600.1 - 0.048 13.6 0.4 41 4.3 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RNA_pol_Rpc82 PF05645.13 EEB05601.2 - 9.2e-34 117.4 3.1 3.9e-32 112.0 3.1 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EEB05601.2 - 4.3e-21 74.8 3.9 2.3e-18 66.0 1.6 2.8 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EEB05601.2 - 4.1e-15 55.5 3.8 3.4e-09 36.5 0.1 3.4 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 EEB05601.2 - 0.081 12.8 0.3 0.6 10.0 0.1 2.6 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.10 EEB05601.2 - 0.13 12.4 0.0 5.9 7.1 0.0 3.2 3 0 0 3 3 3 0 FeoC like transcriptional regulator PBP1_TM PF14812.6 EEB05601.2 - 9.5 6.7 9.4 4.6 7.7 2.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GDPD PF03009.17 EEB05603.2 - 2.8e-73 246.9 0.0 4.4e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EEB05603.2 - 7.3e-22 77.8 0.2 3.4e-11 43.6 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB05603.2 - 1.7e-14 53.7 0.3 1.7e-06 28.2 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEB05603.2 - 2.6e-12 47.0 0.9 1.4e-05 25.6 0.1 4.8 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEB05603.2 - 1.4e-08 34.3 4.6 16 6.5 0.0 6.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EEB05603.2 - 2.8e-08 33.8 4.5 0.12 12.9 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat SPX PF03105.19 EEB05603.2 - 0.0032 17.4 10.9 0.066 13.1 0.2 3.6 3 1 1 4 4 4 2 SPX domain DUF812 PF05667.11 EEB05603.2 - 0.095 11.6 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ERCC4 PF02732.15 EEB05604.1 - 1.4e-16 61.0 2.2 1.7e-16 60.8 0.4 1.9 2 0 0 2 2 2 1 ERCC4 domain SR-25 PF10500.9 EEB05604.1 - 5 6.7 18.2 0.22 11.1 12.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SQHop_cyclase_N PF13249.6 EEB05605.1 - 6.5e-49 166.6 0.0 1.2e-39 136.1 0.0 3.6 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EEB05605.1 - 4.1e-46 157.5 4.3 1.7e-42 145.6 0.4 3.1 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EEB05605.1 - 1.4e-37 127.1 11.6 1.2e-10 41.0 0.1 6.7 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EEB05605.1 - 1.5e-06 27.5 0.1 0.062 12.3 0.0 4.6 3 1 2 5 5 5 2 A-macroglobulin TED domain Mago-bind PF09282.10 EEB05605.1 - 0.00018 21.3 1.3 0.19 11.6 0.0 2.9 3 0 0 3 3 3 2 Mago binding Pec_lyase PF09492.10 EEB05605.1 - 0.0035 16.7 0.2 9.9 5.4 0.0 4.1 5 1 0 5 5 5 2 Pectic acid lyase Mito_carr PF00153.27 EEB05607.2 - 1.5e-60 201.1 3.8 1.7e-20 72.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 EEB05608.1 - 4.4e-16 58.7 0.2 9e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SPATA48 PF15073.6 EEB05608.1 - 0.014 15.6 1.1 0.11 12.8 0.1 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 YfmQ PF10787.9 EEB05608.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Ribosomal_S5_C PF03719.15 EEB05609.1 - 2.3e-27 94.2 0.3 1.5e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EEB05609.1 - 3.5e-19 68.6 1.6 1e-18 67.0 1.6 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L6 PF00347.23 EEB05610.1 - 1.8e-33 115.1 5.0 2.1e-20 73.2 1.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 adh_short PF00106.25 EEB05611.1 - 3.3e-39 134.4 0.0 5.1e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB05611.1 - 5.4e-23 81.8 0.0 7.9e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB05611.1 - 2e-07 31.1 0.9 5e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EEB05611.1 - 0.00032 19.9 0.3 0.00044 19.5 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EEB05611.1 - 0.0017 18.2 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 EEB05611.1 - 0.0034 17.9 0.0 0.009 16.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EEB05611.1 - 0.013 15.7 0.9 0.019 15.2 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EEB05611.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EEB05611.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EEB05611.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EEB05611.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Mpv17_PMP22 PF04117.12 EEB05612.1 - 4.9e-21 74.7 3.8 1e-20 73.7 3.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Vps26 PF03643.15 EEB05613.1 - 1.3e-124 414.6 2.6 1.5e-124 414.4 2.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EEB05613.1 - 0.0013 18.8 2.1 0.04 14.0 0.1 3.1 3 1 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain AAA_18 PF13238.6 EEB05614.1 - 1.4e-11 45.1 0.0 8.3e-11 42.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEB05614.1 - 6.8e-11 42.5 0.0 9e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EEB05614.1 - 3.4e-10 40.3 0.0 4.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase dNK PF01712.19 EEB05614.1 - 4.1e-06 26.8 0.0 0.0095 15.8 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase APS_kinase PF01583.20 EEB05614.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 EEB05614.1 - 6.1e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 EEB05614.1 - 6.6e-05 23.4 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EEB05614.1 - 7.4e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase Zeta_toxin PF06414.12 EEB05614.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 EEB05614.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEB05614.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEB05614.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 EEB05614.1 - 0.043 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EEB05614.1 - 0.045 12.9 0.0 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.12 EEB05614.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EEB05614.1 - 0.052 13.3 0.1 2.1 8.1 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 EEB05614.1 - 0.06 12.5 0.0 0.071 12.3 0.0 1.3 1 1 0 1 1 1 0 TIP49 P-loop domain CoaE PF01121.20 EEB05614.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 EEB05614.1 - 0.084 13.0 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family Tubulin_3 PF14881.6 EEB05614.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain DnaB_C PF03796.15 EEB05614.1 - 0.12 11.7 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EEB05614.1 - 0.15 12.3 0.2 0.49 10.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 EEB05615.1 - 1.9e-12 47.4 4.3 2.7e-09 37.3 0.4 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EEB05615.1 - 4.3e-09 36.8 4.2 0.00066 20.2 0.1 2.8 2 1 0 2 2 2 2 HMG-box domain Catalase-rel PF06628.12 EEB05615.1 - 0.15 12.3 1.5 0.97 9.7 0.0 2.8 4 0 0 4 4 4 0 Catalase-related immune-responsive OTCace PF00185.24 EEB05616.1 - 3.3e-51 173.5 0.6 4.6e-51 173.0 0.6 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EEB05616.1 - 4.6e-44 150.0 0.0 8.7e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.16 EEB05616.1 - 0.0037 16.8 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Nro1 PF12753.7 EEB05616.1 - 0.034 13.1 0.1 5.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 OCD_Mu_crystall PF02423.15 EEB05616.1 - 0.046 12.6 0.2 0.075 12.0 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAT PF04768.13 EEB05617.1 - 4.4e-30 104.6 0.3 1.5e-29 102.8 0.1 2.0 3 0 0 3 3 3 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EEB05617.1 - 1.2e-28 100.0 0.0 2.4e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EEB05617.1 - 5.2e-28 98.3 0.0 1e-27 97.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 EEB05617.1 - 0.015 15.4 0.1 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RNA_pol_Rpb2_6 PF00562.28 EEB05618.1 - 4.6e-127 424.3 0.1 7.4e-127 423.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEB05618.1 - 3.8e-63 212.7 0.1 5.9e-63 212.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEB05618.1 - 9.3e-42 142.8 0.0 2.1e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EEB05618.1 - 1.7e-34 118.0 0.3 4.8e-34 116.6 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EEB05618.1 - 3.2e-23 81.8 2.0 6.2e-23 80.9 1.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EEB05618.1 - 5e-18 65.0 0.1 1.1e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EEB05618.1 - 1.5e-10 41.5 0.5 4.7e-10 39.9 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RHD_dimer PF16179.5 EEB05618.1 - 0.15 12.1 0.1 0.4 10.7 0.1 1.6 1 0 0 1 1 1 0 Rel homology dimerisation domain PIP5K PF01504.18 EEB05619.1 - 1.3e-41 142.6 3.7 6.9e-33 114.0 0.3 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EEB05619.1 - 1.3e-25 90.0 0.0 2.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EEB05619.1 - 4.1e-15 55.7 10.1 4.1e-15 55.7 10.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 EEB05620.2 - 1.8e-30 104.5 3.0 1.4e-09 38.4 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05620.2 - 5.8e-10 39.3 0.0 0.0019 18.5 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 EEB05621.1 - 5.8e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain EnY2 PF10163.9 EEB05622.1 - 1.9e-20 73.0 0.2 2.3e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 SIX1_SD PF16878.5 EEB05622.1 - 0.0041 17.6 0.5 0.0051 17.3 0.5 1.2 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Ofd1_CTDD PF10637.9 EEB05623.1 - 2.3e-76 256.5 0.0 1.9e-73 246.9 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EEB05623.1 - 1.1e-30 106.2 0.0 2.7e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EEB05623.1 - 2e-14 54.2 0.0 4.2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRP1_N PF06424.12 EEB05624.1 - 1.8e-48 164.7 3.0 1.8e-48 164.7 3.0 1.9 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EEB05624.1 - 2.2e-23 80.9 17.7 0.005 17.6 0.0 13.6 6 3 9 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05624.1 - 6.7e-20 71.4 2.1 0.00037 20.9 0.0 8.6 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05624.1 - 9.2e-09 35.8 0.4 0.5 11.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat NRDE-2 PF08424.10 EEB05624.1 - 4.8e-08 32.5 27.4 5e-06 25.9 4.4 5.0 2 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_11 PF13414.6 EEB05624.1 - 8.6e-08 31.7 0.0 2.1 8.1 0.0 6.7 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.17 EEB05624.1 - 1.5e-07 31.0 7.3 9.1 6.7 0.0 9.2 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05624.1 - 5.6e-07 29.5 0.3 19 5.9 0.0 8.1 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05624.1 - 1e-06 28.4 0.3 19 5.8 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Suf PF05843.14 EEB05624.1 - 8.3e-06 26.0 10.9 0.0071 16.4 0.0 4.7 3 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 EEB05624.1 - 8.8e-06 25.3 0.0 3 7.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05624.1 - 0.0015 19.1 3.6 18 6.2 0.0 6.9 9 0 0 9 9 7 0 Tetratricopeptide repeat UPF0181 PF03701.14 EEB05624.1 - 0.038 13.6 0.6 0.1 12.2 0.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) TPR_21 PF09976.9 EEB05624.1 - 0.043 13.5 10.9 3.8 7.2 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain UCH PF00443.29 EEB05625.1 - 1.5e-39 136.1 0.2 2.4e-39 135.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEB05625.1 - 1.2e-24 86.4 12.4 4e-20 71.9 3.4 3.2 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EEB05625.1 - 5.9e-24 85.2 3.0 2e-23 83.5 0.5 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EEB05625.1 - 4.1e-21 74.5 0.2 3.2e-09 36.5 0.5 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EEB05625.1 - 1.1e-17 63.5 2.2 1.1e-17 63.5 2.2 3.7 3 0 0 3 3 3 2 Variant UBP zinc finger ATG7_N PF16420.5 EEB05626.1 - 1.3e-66 225.3 0.4 1.9e-66 224.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EEB05626.1 - 7.5e-46 156.5 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 EEB05626.1 - 0.005 16.2 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EEB05626.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EEB05626.1 - 0.094 12.8 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase LRS4 PF10422.9 EEB05627.1 - 8.5e-11 41.9 20.5 8.5e-11 41.9 20.5 2.2 1 1 1 2 2 2 1 Monopolin complex subunit LRS4 Fib_alpha PF08702.10 EEB05627.1 - 0.0003 21.0 6.9 0.0003 21.0 6.9 2.9 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EEB05627.1 - 0.00034 20.9 15.7 0.0059 16.9 0.8 2.8 1 1 0 2 2 2 2 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.9 EEB05627.1 - 0.011 15.9 26.2 0.024 14.9 15.4 3.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Vps51 PF08700.11 EEB05627.1 - 0.053 13.6 10.8 2.4 8.3 5.2 3.2 3 1 0 3 3 2 0 Vps51/Vps67 Fez1 PF06818.15 EEB05627.1 - 0.053 14.0 23.6 0.44 11.0 6.1 2.4 1 1 1 2 2 2 0 Fez1 CC2-LZ PF16516.5 EEB05627.1 - 0.073 13.4 15.4 0.37 11.2 1.1 2.9 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HrpB7 PF09486.10 EEB05627.1 - 0.076 13.4 6.0 4.5 7.6 0.8 2.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 EEB05627.1 - 0.11 11.4 25.7 0.056 12.3 12.1 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein ERM PF00769.19 EEB05627.1 - 0.13 12.1 22.5 4.6 7.0 21.6 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EEB05627.1 - 0.23 11.5 18.2 0.46 10.6 17.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 EEB05627.1 - 0.35 10.1 16.2 0.12 11.6 6.9 2.4 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1664 PF07889.12 EEB05627.1 - 0.35 10.9 13.0 1.2 9.2 4.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EEB05627.1 - 0.39 10.8 25.8 1.1 9.4 4.8 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EEB05627.1 - 0.48 9.7 10.2 1.1 8.6 10.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 EEB05627.1 - 2.2 8.5 17.9 8.2 6.7 0.3 3.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF2730 PF10805.8 EEB05627.1 - 2.6 8.2 10.5 9.3 6.4 3.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) TSNAXIP1_N PF15739.5 EEB05627.1 - 3.9 7.9 14.5 0.26 11.7 4.1 3.0 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF3552 PF12072.8 EEB05627.1 - 4.7 6.6 25.3 6.2 6.2 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) FlaC_arch PF05377.11 EEB05627.1 - 6.1 7.3 12.1 8.6 6.8 2.4 4.1 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 EEB05627.1 - 6.3 6.6 21.7 1.3 8.8 11.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Sec20 PF03908.13 EEB05627.1 - 7.7 6.5 11.0 0.39 10.7 2.9 2.9 1 1 1 3 3 3 0 Sec20 APG6_N PF17675.1 EEB05627.1 - 8.6 6.9 24.3 0.69 10.4 14.2 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Pal1 PF08316.11 EEB05628.1 - 1.2e-27 97.3 0.0 7.3e-27 94.8 0.0 2.3 2 1 0 2 2 2 1 Pal1 cell morphology protein Pkinase PF00069.25 EEB05629.1 - 3.7e-43 147.8 0.0 6.4e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05629.1 - 1.9e-32 112.6 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB05629.1 - 5.4e-06 25.6 1.5 0.00041 19.4 0.0 2.6 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EEB05629.1 - 0.1 12.5 0.0 7 6.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3535 PF12054.8 EEB05630.2 - 2.9e-104 349.8 5.1 8.6e-102 341.6 5.3 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EEB05630.2 - 7.5e-51 172.9 3.1 1.8e-49 168.4 0.2 2.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.22 EEB05630.2 - 4.1e-18 63.9 8.9 0.0037 17.4 0.1 9.5 9 0 0 9 9 9 2 HEAT repeat Helicase_C PF00271.31 EEB05630.2 - 4.1e-18 65.7 0.1 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 EEB05630.2 - 4.3e-08 33.4 0.1 0.0017 18.7 0.1 5.2 4 1 1 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EEB05630.2 - 7.7e-08 32.8 1.6 0.066 13.8 0.0 5.3 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EEB05630.2 - 4.3e-05 23.5 5.3 0.00086 19.3 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EEB05630.2 - 5.8e-05 22.8 0.9 0.61 9.6 0.0 3.8 3 0 0 3 3 3 2 CLASP N terminal ResIII PF04851.15 EEB05630.2 - 0.00079 19.5 1.0 0.25 11.3 0.0 3.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TAF6_C PF07571.13 EEB05630.2 - 0.0036 17.6 0.3 3.1 8.2 0.0 5.0 5 1 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 EEB05630.2 - 0.0056 17.2 4.8 11 6.7 0.0 6.1 7 0 0 7 7 6 1 HEAT-like repeat SWI2_SNF2 PF18766.1 EEB05630.2 - 0.084 12.5 0.3 0.78 9.4 0.5 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase ACDC PF14733.6 EEB05630.2 - 1.4 9.3 6.3 1.1 9.7 1.0 3.3 3 0 0 3 3 3 0 AP2-coincident C-terminal F-box-like PF12937.7 EEB05631.1 - 1.3e-10 41.0 2.0 4.3e-10 39.3 2.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EEB05631.1 - 1.9e-08 34.5 17.8 0.44 11.0 0.1 8.0 3 1 5 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEB05631.1 - 2.9e-07 30.0 17.0 0.77 10.0 0.0 9.3 11 0 0 11 11 11 3 Leucine Rich repeat F-box PF00646.33 EEB05631.1 - 8.5e-07 28.7 3.0 1.3e-06 28.1 1.1 2.3 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 EEB05631.1 - 0.66 9.8 14.1 30 4.5 0.1 6.2 4 2 3 7 7 7 0 Leucine rich repeat Usp PF00582.26 EEB05632.1 - 2.6e-21 76.6 0.0 3.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family tRNA-synt_1d PF00750.19 EEB05633.2 - 1.2e-104 350.0 3.1 1.6e-104 349.6 3.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EEB05633.2 - 1.1e-22 80.5 1.3 2.1e-22 79.5 0.2 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EEB05633.2 - 0.0043 17.6 0.1 0.014 16.0 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF2250 PF10007.9 EEB05633.2 - 0.027 14.6 0.3 0.093 12.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) POT1 PF02765.17 EEB05633.2 - 0.081 12.8 0.1 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 BTB PF00651.31 EEB05635.1 - 1.8e-08 34.6 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain KH_8 PF17903.1 EEB05636.1 - 7.4e-30 102.9 0.0 1.4e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EEB05636.1 - 0.012 15.4 0.1 0.043 13.6 0.1 1.9 2 0 0 2 2 2 0 KH domain KH_4 PF13083.6 EEB05636.1 - 0.013 15.4 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 KH domain MMR_HSR1 PF01926.23 EEB05638.1 - 5e-15 55.6 0.1 4.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB05638.1 - 1.5e-09 37.6 0.1 2.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EEB05638.1 - 3.3e-06 26.6 0.0 6.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EEB05638.1 - 3.5e-05 23.8 0.1 0.0001 22.3 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EEB05638.1 - 0.0024 17.9 0.8 0.071 13.2 0.1 2.7 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 EEB05638.1 - 0.0036 17.7 0.3 0.014 15.8 0.0 2.0 2 1 1 3 3 3 1 AAA ATPase domain MeaB PF03308.16 EEB05638.1 - 0.0052 15.8 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EEB05638.1 - 0.025 15.1 0.0 0.065 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain IIGP PF05049.13 EEB05638.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EEB05638.1 - 0.041 14.1 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Aldedh PF00171.22 EEB05639.1 - 3.9e-20 71.8 1.6 4.2e-15 55.2 0.4 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1542 PF07564.11 EEB05639.1 - 0.00077 19.5 2.8 0.00099 19.2 1.3 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) DUF1487 PF07368.11 EEB05639.1 - 0.039 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.25 EEB05640.1 - 8e-63 212.3 0.0 6e-62 209.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05640.1 - 2.1e-27 96.0 0.0 4.2e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EEB05640.1 - 1.6e-05 24.4 1.5 0.0025 17.2 0.0 2.6 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEB05640.1 - 3.7e-05 22.8 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEB05640.1 - 0.00085 18.7 0.0 0.0017 17.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEB05640.1 - 0.0033 17.4 0.6 0.061 13.2 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 EEB05640.1 - 0.0086 16.8 0.2 0.02 15.6 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 EEB05640.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EEB05640.1 - 0.037 12.8 0.5 0.06 12.1 0.5 1.5 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EEB05640.1 - 0.17 11.5 0.1 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 RIO1 family JAB PF01398.21 EEB05641.1 - 1.8e-09 37.6 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dec-1 PF04624.14 EEB05641.1 - 9 6.2 7.9 0.24 11.3 1.1 1.8 2 0 0 2 2 2 0 Dec-1 repeat Septin PF00735.18 EEB05642.1 - 1.5e-109 365.6 0.4 1.8e-109 365.4 0.4 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEB05642.1 - 4.8e-09 36.3 0.0 1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEB05642.1 - 7.9e-07 28.8 0.2 2.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB05642.1 - 2.9e-06 27.3 0.1 3.6e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EEB05642.1 - 1.5e-05 25.1 1.0 0.054 13.6 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EEB05642.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 EEB05642.1 - 0.00013 22.5 0.0 0.00028 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EEB05642.1 - 0.00016 22.1 0.0 0.00049 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EEB05642.1 - 0.00071 19.6 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEB05642.1 - 0.00081 18.9 0.0 0.003 17.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EEB05642.1 - 0.0013 19.0 0.0 0.023 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEB05642.1 - 0.0024 18.2 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 EEB05642.1 - 0.003 17.8 0.2 0.0077 16.4 0.0 1.9 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 EEB05642.1 - 0.0031 16.6 0.1 0.0061 15.6 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EEB05642.1 - 0.0036 17.0 0.1 0.007 16.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RHD3 PF05879.12 EEB05642.1 - 0.0048 15.1 0.0 0.0081 14.4 0.0 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Gtr1_RagA PF04670.12 EEB05642.1 - 0.0052 16.2 0.2 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EEB05642.1 - 0.0073 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EEB05642.1 - 0.0077 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.22 EEB05642.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EEB05642.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IIGP PF05049.13 EEB05642.1 - 0.021 13.9 0.1 0.048 12.7 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EEB05642.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain SRPRB PF09439.10 EEB05642.1 - 0.027 13.9 0.1 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 EEB05642.1 - 0.027 13.6 0.0 0.06 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLP1_P PF16575.5 EEB05642.1 - 0.032 14.0 0.3 3.3 7.5 0.0 2.3 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Guanylate_kin PF00625.21 EEB05642.1 - 0.04 13.6 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase AAA_18 PF13238.6 EEB05642.1 - 0.051 14.1 0.3 0.12 12.9 0.1 1.9 2 1 0 2 2 1 0 AAA domain AAA_32 PF13654.6 EEB05642.1 - 0.052 12.3 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 EEB05642.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Sigma54_activat PF00158.26 EEB05642.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EEB05642.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB05642.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EEB05642.1 - 0.12 12.1 0.2 0.25 11.1 0.2 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zn_clus PF00172.18 EEB05643.2 - 1.5e-08 34.6 9.0 2.7e-08 33.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5399 PF17377.2 EEB05643.2 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5399) ANAPC4_WD40 PF12894.7 EEB05644.1 - 8.3e-18 64.5 9.3 3e-06 27.5 0.2 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB05644.1 - 9.1e-12 45.3 20.4 3.6e-05 24.4 0.3 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EEB05644.1 - 4.3e-07 29.2 0.4 1.9e-05 23.8 0.1 3.1 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEB05644.1 - 6.5e-06 26.2 1.5 0.0089 15.9 0.6 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Glyco_hyd_101C PF17451.2 EEB05644.1 - 0.11 12.8 0.3 24 5.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Glyco_hydro81C PF17652.1 EEB05645.1 - 1e-147 492.0 4.4 1.4e-147 491.5 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEB05645.1 - 1.2e-89 300.7 2.3 1.9e-89 300.1 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Carb_bind PF10645.9 EEB05645.1 - 7.8e-53 176.5 48.0 1.2e-17 63.9 12.7 3.5 3 0 0 3 3 3 3 Carbohydrate binding Sod_Cu PF00080.20 EEB05646.1 - 3.2e-45 153.8 2.6 3.6e-45 153.6 2.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PhoLip_ATPase_C PF16212.5 EEB05647.1 - 4.3e-65 219.9 25.1 4.3e-65 219.9 25.1 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEB05647.1 - 3.1e-22 78.0 0.4 3.1e-22 78.0 0.4 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EEB05647.1 - 4.3e-13 49.2 0.1 4.3e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEB05647.1 - 1.7e-12 48.1 0.6 2.9e-05 24.4 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB05647.1 - 3e-12 46.5 0.0 1.8e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEB05647.1 - 3.3e-05 23.7 0.1 0.00014 21.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB05647.1 - 0.071 13.2 0.5 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MKT1_C PF12246.8 EEB05648.2 - 9.3e-43 146.2 0.0 1.5e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EEB05648.2 - 2.4e-33 114.3 0.2 5.2e-31 106.9 0.0 3.3 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EEB05648.2 - 5.6e-06 26.8 0.0 2.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EEB05648.2 - 0.027 14.8 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Mito_carr PF00153.27 EEB05649.1 - 2.7e-54 181.1 4.0 9.1e-17 60.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NTP_transf_9 PF04248.12 EEB05650.1 - 0.011 15.6 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Aminotran_3 PF00202.21 EEB05651.1 - 3.6e-42 144.4 0.0 4.4e-38 131.0 0.0 3.8 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EEB05651.1 - 1.1e-16 61.3 0.0 2.7e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Aldedh PF00171.22 EEB05652.1 - 1.9e-156 521.2 1.2 2.1e-156 521.0 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_7 PF13176.6 EEB05653.2 - 1e-05 25.2 2.9 0.027 14.5 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05653.2 - 1.6e-05 24.8 10.9 0.54 10.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05653.2 - 5.6e-05 23.3 6.3 0.58 10.5 0.1 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat Sel1 PF08238.12 EEB05653.2 - 0.00015 22.3 1.0 0.48 11.2 0.0 4.8 5 0 0 5 5 4 1 Sel1 repeat TPR_17 PF13431.6 EEB05653.2 - 0.0026 18.0 5.8 0.26 11.8 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05653.2 - 0.012 15.5 1.1 0.59 10.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEB05653.2 - 0.014 15.3 4.7 1.6 8.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05653.2 - 0.023 15.5 1.4 40 5.4 0.3 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF5032 PF16435.5 EEB05653.2 - 0.024 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) TPR_16 PF13432.6 EEB05653.2 - 0.032 14.9 5.3 5.5 7.7 1.3 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05653.2 - 0.051 13.7 11.8 2 8.7 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05653.2 - 0.55 11.0 4.7 13 6.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Hat1_N PF10394.9 EEB05654.2 - 1.2e-29 103.6 0.1 2.3e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 EEB05654.2 - 0.0006 19.5 0.7 0.0018 17.9 0.4 1.9 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_1 PF00583.25 EEB05654.2 - 0.026 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB05654.2 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1899 PF08953.11 EEB05655.1 - 6.5e-32 109.2 0.0 1.1e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EEB05655.1 - 3.4e-21 74.9 0.4 9.2e-21 73.5 0.4 1.8 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EEB05655.1 - 1.1e-14 54.6 10.0 0.00057 20.6 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05655.1 - 2.9e-05 24.3 0.0 0.0084 16.4 0.0 3.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FlxA PF14282.6 EEB05655.1 - 0.013 15.5 1.2 0.013 15.5 1.2 1.7 2 0 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.6 EEB05655.1 - 0.25 11.8 2.1 0.58 10.6 2.1 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MerR-DNA-bind PF09278.11 EEB05655.1 - 0.55 10.8 2.4 8.8 7.0 2.1 2.3 1 1 1 2 2 2 0 MerR, DNA binding Haspin_kinase PF12330.8 EEB05656.1 - 6.3e-71 239.2 2.7 6.3e-71 239.2 2.7 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Ish1 PF10281.9 EEB05657.1 - 3.9e-16 59.1 10.7 3.6e-05 24.0 0.1 6.2 7 0 0 7 7 7 5 Putative stress-responsive nuclear envelope protein DUF4129 PF13559.6 EEB05657.1 - 0.0092 16.2 1.7 0.041 14.2 0.6 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4129) SRI PF08236.11 EEB05657.1 - 0.04 14.1 1.6 0.72 10.1 0.0 2.5 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DER1 PF04511.15 EEB05658.1 - 1.9e-26 93.2 9.6 2.2e-26 93.0 9.6 1.0 1 0 0 1 1 1 1 Der1-like family Cation_ATPase_C PF00689.21 EEB05658.1 - 0.022 14.5 4.6 0.027 14.2 4.6 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Cohesin_load PF10345.9 EEB05659.1 - 2.9e-64 217.6 19.0 4.8e-63 213.5 19.0 2.0 1 1 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 EEB05659.1 - 0.059 13.7 6.4 18 5.7 0.3 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat dUTPase PF00692.19 EEB05659.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 dUTPase TGT PF01702.18 EEB05660.1 - 1.2e-142 475.2 0.1 1.4e-142 475.0 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.11 EEB05661.1 - 9.7e-22 77.3 1.9 3.2e-19 69.1 0.0 3.1 2 1 0 3 3 3 3 Mis6 His_Phos_1 PF00300.22 EEB05662.1 - 8.3e-37 126.8 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Nitro_FeMo-Co PF02579.17 EEB05662.1 - 0.081 13.3 0.1 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor PUF PF00806.19 EEB05663.1 - 4.3e-62 202.4 10.8 1.8e-08 33.6 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 EEB05663.1 - 0.0094 15.8 0.2 14 5.6 0.0 4.0 5 1 1 6 6 6 2 Single Cache domain 2 zf-Tim10_DDP PF02953.15 EEB05664.1 - 1.5e-21 75.8 5.0 1.8e-21 75.5 5.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EEB05664.1 - 0.029 14.0 4.2 0.036 13.8 4.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF5308 PF17233.2 EEB05665.1 - 5.5e-07 30.0 0.0 8.8e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Catalase_C PF18011.1 EEB05665.1 - 0.069 12.8 0.0 0.097 12.3 0.0 1.4 1 1 0 1 1 1 0 C-terminal domain found in long catalases Ribosomal_L28e PF01778.17 EEB05666.1 - 3.8e-37 127.6 0.4 8.3e-37 126.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EEB05666.1 - 6e-28 97.4 11.4 6e-28 97.4 11.4 2.6 2 1 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 EEB05666.1 - 0.00038 20.3 2.7 0.00056 19.7 2.7 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain BUD22 PF09073.10 EEB05666.1 - 0.0031 16.9 25.2 0.005 16.2 25.2 1.3 1 1 0 1 1 1 1 BUD22 DUF2462 PF09495.10 EEB05666.1 - 0.038 14.7 0.3 0.038 14.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) SEEEED PF14797.6 EEB05666.1 - 0.73 10.0 26.8 1.2 9.3 26.8 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex YL1 PF05764.13 EEB05666.1 - 1.5 8.9 29.9 2.1 8.4 23.3 2.2 2 0 0 2 2 2 0 YL1 nuclear protein SAPS PF04499.15 EEB05666.1 - 3 6.5 9.9 3.9 6.2 9.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 EEB05666.1 - 5.8 5.0 24.5 8.3 4.5 24.5 1.2 1 0 0 1 1 1 0 Nop14-like family GRA6 PF05084.13 EEB05666.1 - 9 6.2 8.6 13 5.6 8.6 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Pkinase PF00069.25 EEB05667.2 - 5.4e-34 117.7 0.0 5e-19 68.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05667.2 - 2.7e-16 59.6 0.0 1.4e-06 27.8 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase HALZ PF02183.18 EEB05667.2 - 0.05 13.8 0.5 0.098 12.9 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper RNA_pol_Rpc4 PF05132.14 EEB05667.2 - 0.11 13.0 0.9 0.19 12.2 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tub_N PF16322.5 EEB05667.2 - 0.26 11.7 9.5 0.51 10.7 9.5 1.4 1 0 0 1 1 1 0 Tubby N-terminal SNO PF01174.19 EEB05668.1 - 6e-48 163.2 0.0 7.2e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EEB05668.1 - 4.6e-07 29.6 0.0 8.8e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EEB05668.1 - 0.00012 21.9 0.0 0.00064 19.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EEB05668.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EEB05668.1 - 0.0021 17.9 0.1 0.0043 16.9 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 EEB05668.1 - 0.0033 17.2 0.8 0.043 13.6 0.8 2.6 1 1 0 1 1 1 1 Peptidase C26 RNA_pol_I_TF PF04090.12 EEB05669.1 - 8.6e-29 100.5 0.0 3.3e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_6 PF13174.6 EEB05669.1 - 7e-06 26.4 4.1 0.0025 18.3 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.6 EEB05669.1 - 0.00017 21.4 0.0 0.00067 19.4 0.0 1.8 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_9 PF13371.6 EEB05669.1 - 0.00026 21.1 1.9 0.34 11.1 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05669.1 - 0.0044 17.0 5.4 1.4 9.2 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05669.1 - 0.035 14.3 0.6 3.3 8.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05669.1 - 0.037 14.7 0.8 11 6.8 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05669.1 - 0.094 13.2 0.6 0.97 10.0 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05669.1 - 0.29 12.1 6.3 2.6 9.1 0.1 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat Ank_4 PF13637.6 EEB05670.1 - 1.9e-15 57.0 7.7 6.4e-08 33.0 0.4 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB05670.1 - 1e-11 45.3 5.0 8.9e-06 26.2 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EEB05670.1 - 1.4e-09 38.0 3.8 0.00042 20.6 0.7 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EEB05670.1 - 9.9e-07 28.6 5.3 0.00031 20.9 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EEB05670.1 - 7.2e-06 26.2 2.1 0.15 12.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EEB05670.1 - 0.00013 21.8 0.1 0.0025 17.6 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Pribosyltran PF00156.27 EEB05671.1 - 5.3e-15 55.3 0.1 6.9e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEB05671.1 - 0.0054 16.2 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NAT PF04768.13 EEB05672.1 - 5.7e-48 162.8 0.0 1.1e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Sld5 PF05916.11 EEB05673.1 - 3.1e-23 82.3 1.5 5.3e-23 81.6 1.5 1.4 1 0 0 1 1 1 1 GINS complex protein Nbl1_Borealin_N PF10444.9 EEB05674.1 - 7.7e-16 57.5 0.6 1.3e-15 56.8 0.6 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal CBFB_NFYA PF02045.15 EEB05675.1 - 7.9e-26 90.5 9.2 7.9e-26 90.5 9.2 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SOG2 PF10428.9 EEB05675.1 - 1.5 7.9 17.3 2.2 7.4 17.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 EEB05675.1 - 3.5 4.6 14.8 4.5 4.2 14.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 EEB05675.1 - 4.8 5.3 20.2 5.9 5.0 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TspO_MBR PF03073.15 EEB05676.1 - 4.9e-40 136.7 12.8 6.2e-40 136.4 12.8 1.0 1 0 0 1 1 1 1 TspO/MBR family BAR PF03114.18 EEB05677.1 - 1.6e-59 201.5 0.5 1.9e-59 201.2 0.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EEB05677.1 - 2.9e-06 27.2 0.1 4.2e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 EEB05677.1 - 0.046 13.3 0.3 0.085 12.4 0.3 1.6 1 1 0 1 1 1 0 Arfaptin-like domain P_C10 PF14974.6 EEB05677.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein C10 DUF445 PF04286.12 EEB05677.1 - 0.083 12.7 0.2 0.48 10.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) HisKA_3 PF07730.13 EEB05677.1 - 0.6 10.7 3.1 2.2 8.9 0.5 2.8 3 0 0 3 3 3 0 Histidine kinase DUF3546 PF12066.8 EEB05678.2 - 5.1e-11 42.8 3.7 1.5e-10 41.2 3.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) LPD1 PF18796.1 EEB05678.2 - 0.061 13.4 2.5 0.066 13.3 0.6 2.1 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 1 TPR_2 PF07719.17 EEB05679.2 - 1.4e-16 59.2 1.1 0.0011 18.9 0.0 6.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05679.2 - 6.1e-12 44.8 1.0 0.0059 16.4 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEB05679.2 - 7.4e-10 38.4 0.5 0.1 12.3 0.0 4.8 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.6 EEB05679.2 - 4.8e-07 30.1 2.9 0.0024 18.6 0.3 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05679.2 - 7.2e-07 29.7 0.1 0.026 15.2 0.2 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05679.2 - 1.4e-05 25.5 4.9 0.12 12.9 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB05679.2 - 4.3e-05 23.6 0.9 0.81 9.9 0.1 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05679.2 - 9.9e-05 22.5 1.9 0.94 10.0 0.0 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB05679.2 - 0.0007 19.4 0.6 15 5.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05679.2 - 0.012 16.2 1.3 15 6.5 0.0 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05679.2 - 0.023 14.9 4.1 10 6.6 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEB05679.2 - 0.025 14.9 0.0 0.025 14.9 0.0 3.3 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EEB05679.2 - 0.038 14.1 3.6 4.7 7.4 0.1 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EEB05679.2 - 0.051 14.0 4.6 6.4 7.2 0.6 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EEB05679.2 - 0.061 13.6 8.4 0.82 9.9 0.3 3.7 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Phage_GP20 PF06810.11 EEB05679.2 - 0.08 12.7 6.1 0.15 11.8 6.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1674 PF07896.12 EEB05680.2 - 1.4e-14 54.3 4.8 2.9e-14 53.3 4.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Pkinase PF00069.25 EEB05681.1 - 1.1e-60 205.2 0.4 2.2e-39 135.4 0.3 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05681.1 - 3.1e-29 102.0 0.5 2.9e-20 72.6 0.1 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB05681.1 - 0.00012 21.5 0.2 0.0007 19.0 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EEB05681.1 - 0.053 12.9 0.4 0.15 11.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phosphodiest PF01663.22 EEB05682.1 - 1.1e-76 258.8 2.1 1.3e-76 258.5 2.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPP_enzyme_N PF02776.18 EEB05683.2 - 1.9e-47 161.0 0.1 4e-47 160.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEB05683.2 - 5.6e-34 116.8 0.0 2.1e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEB05683.2 - 4.6e-23 81.7 0.1 1.1e-22 80.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EEB05683.2 - 0.0022 17.3 0.1 0.0042 16.3 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.16 EEB05683.2 - 0.024 14.4 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Peripla_BP_4 PF13407.6 EEB05683.2 - 0.12 12.0 1.1 0.18 11.4 0.0 1.9 3 0 0 3 3 3 0 Periplasmic binding protein domain Pyridox_oxase_2 PF12766.7 EEB05684.2 - 6e-21 74.9 0.0 9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1935 PF09149.10 EEB05685.1 - 0.063 13.7 0.1 0.65 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) His_Phos_2 PF00328.22 EEB05687.1 - 4.5e-33 115.1 0.0 6.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA PF00004.29 EEB05688.1 - 6.5e-42 143.1 0.0 1.2e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEB05688.1 - 2.4e-10 40.2 0.1 5.4e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EEB05688.1 - 3.6e-09 36.3 0.3 7.2e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EEB05688.1 - 2.1e-06 28.0 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEB05688.1 - 1.1e-05 25.4 0.1 4.3e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEB05688.1 - 1.2e-05 25.6 0.7 0.028 14.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 EEB05688.1 - 1.9e-05 24.0 0.0 3.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EEB05688.1 - 0.00018 21.9 1.5 0.0033 17.8 0.5 2.8 2 1 0 2 2 2 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 EEB05688.1 - 0.00041 19.9 0.9 0.0014 18.3 0.0 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain RuvB_N PF05496.12 EEB05688.1 - 0.00042 20.1 0.0 0.00087 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EEB05688.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EEB05688.1 - 0.0036 16.7 0.2 0.37 10.1 0.1 2.4 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.22 EEB05688.1 - 0.0075 16.6 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EEB05688.1 - 0.0093 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEB05688.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EEB05688.1 - 0.02 14.9 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EEB05688.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB05688.1 - 0.029 14.1 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EEB05688.1 - 0.031 13.8 0.2 0.24 10.9 0.2 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 EEB05688.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EEB05688.1 - 0.042 14.4 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEB05688.1 - 0.045 13.5 1.1 0.15 11.7 0.3 2.2 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EEB05688.1 - 0.046 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEB05688.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Nuc_deoxyrib_tr PF05014.15 EEB05688.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase NB-ARC PF00931.22 EEB05688.1 - 0.11 11.7 0.2 0.65 9.1 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain TsaE PF02367.17 EEB05688.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEB05688.1 - 0.18 11.5 0.3 0.6 9.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB05688.1 - 0.18 11.3 0.9 1.2 8.6 0.3 2.3 1 1 1 2 2 2 0 AAA domain KH_1 PF00013.29 EEB05689.1 - 1.2e-49 166.0 3.7 4.6e-16 58.4 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEB05689.1 - 3.4e-12 46.0 0.4 0.0056 16.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEB05689.1 - 3.7e-10 39.5 1.3 0.098 12.5 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EEB05689.1 - 2.3e-06 27.5 0.0 0.0067 16.4 0.0 3.2 3 0 0 3 3 3 2 KH-like RNA-binding domain Aminotran_1_2 PF00155.21 EEB05690.1 - 1.3e-77 261.4 0.0 1.6e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II YcxB PF14317.6 EEB05690.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 YcxB-like protein FA_hydroxylase PF04116.13 EEB05692.1 - 6.7e-22 78.3 17.0 6.7e-22 78.3 17.0 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pkinase PF00069.25 EEB05693.1 - 6.6e-67 225.6 0.0 7.8e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05693.1 - 4.6e-25 88.4 0.0 6.2e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05693.1 - 7.6e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEB05693.1 - 0.00079 19.4 0.7 0.0039 17.1 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEB05693.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EEB05693.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1689 PF07954.11 EEB05693.1 - 0.084 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) EF-hand_7 PF13499.6 EEB05694.1 - 5.7e-10 39.5 0.2 6.5e-10 39.3 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB05694.1 - 2.7e-07 29.7 0.5 0.00072 18.9 0.0 2.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EEB05694.1 - 3.7e-07 29.6 0.2 0.00018 21.2 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EEB05694.1 - 3.1e-06 26.4 0.4 0.029 13.9 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EEB05694.1 - 0.00011 22.0 0.3 0.0012 18.7 0.2 2.2 1 1 0 1 1 1 1 EF-hand domain pair TerB PF05099.13 EEB05694.1 - 0.033 14.1 0.2 0.037 14.0 0.2 1.0 1 0 0 1 1 1 0 Tellurite resistance protein TerB JAB PF01398.21 EEB05695.2 - 5.8e-27 94.0 0.1 8.9e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EEB05695.2 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Coq4 PF05019.13 EEB05696.1 - 2e-94 315.1 0.0 2.2e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Spb1_C PF07780.12 EEB05697.1 - 6.2e-80 267.8 19.0 6.2e-80 267.8 19.0 3.7 4 1 1 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.19 EEB05697.1 - 2.5e-55 187.3 0.0 4.5e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EEB05697.1 - 2.1e-47 161.0 6.4 2.1e-47 161.0 6.4 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) MAP65_ASE1 PF03999.12 EEB05698.1 - 9e-13 47.8 36.0 3.1e-12 46.0 36.0 1.9 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RecG_N PF17190.4 EEB05698.1 - 0.047 14.4 6.6 0.89 10.3 0.5 3.7 3 0 0 3 3 3 0 RecG N-terminal helical domain ECM11 PF15463.6 EEB05698.1 - 0.6 10.7 6.1 2 9.0 0.8 3.7 3 1 0 3 3 3 0 Extracellular mutant protein 11 RsbRD_N PF14361.6 EEB05698.1 - 0.64 10.7 4.0 1.5 9.5 0.1 3.6 3 2 1 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF4709 PF15821.5 EEB05698.1 - 3.4 8.0 8.3 0.45 10.8 0.9 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4709) DUF2681 PF10883.8 EEB05699.1 - 1.4 9.4 9.8 4.3 7.8 9.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2015 PF09435.10 EEB05700.1 - 3.3e-31 107.4 0.0 4e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EEB05701.1 - 9.1e-29 100.5 0.3 1e-28 100.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family PINIT PF14324.6 EEB05702.1 - 2.2e-30 105.9 0.5 8.5e-30 104.0 0.1 2.1 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 EEB05702.1 - 4.7e-23 80.7 3.9 8e-23 79.9 3.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EEB05702.1 - 9.4e-07 28.6 0.9 1.9e-06 27.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EEB05702.1 - 3.7e-06 26.6 1.1 6e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 SAP domain PDCD2_C PF04194.13 EEB05702.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Prok-RING_4 PF14447.6 EEB05702.1 - 0.21 11.5 1.8 0.31 10.9 1.1 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EEB05702.1 - 0.58 10.0 2.9 1.1 9.1 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB05702.1 - 1 9.6 2.8 2.1 8.5 2.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MCM_bind PF09739.9 EEB05703.1 - 5.2e-68 229.9 1.0 1.1e-50 172.8 0.0 2.9 1 1 2 3 3 3 3 Mini-chromosome maintenance replisome factor Arm-DNA-bind_1 PF09003.10 EEB05703.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain Rep_fac_C PF08542.11 EEB05704.1 - 4e-22 78.4 0.0 1.4e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EEB05704.1 - 2.6e-13 50.1 0.0 1.1e-10 41.5 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EEB05704.1 - 6.9e-12 45.9 0.1 1.5e-11 44.8 0.0 1.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEB05704.1 - 2e-06 27.8 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB05704.1 - 4.5e-06 27.1 0.0 0.00023 21.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EEB05704.1 - 8.2e-06 25.7 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EEB05704.1 - 5.6e-05 23.4 0.1 0.017 15.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEB05704.1 - 8.5e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EEB05704.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EEB05704.1 - 0.00014 21.7 0.0 0.00034 20.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EEB05704.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EEB05704.1 - 0.00056 20.2 0.3 0.0036 17.6 0.1 2.3 2 1 1 3 3 2 1 AAA C-terminal domain Mg_chelatase PF01078.21 EEB05704.1 - 0.004 16.5 0.2 0.07 12.5 0.1 2.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EEB05704.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 EEB05704.1 - 0.016 14.6 0.0 6 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 EEB05704.1 - 0.022 14.7 0.3 0.16 11.9 0.1 2.2 1 1 1 2 2 2 0 NTPase MeaB PF03308.16 EEB05704.1 - 0.025 13.6 0.1 0.07 12.1 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EEB05704.1 - 0.047 13.7 0.6 4.6 7.2 0.2 3.3 3 2 0 3 3 2 0 AAA domain (dynein-related subfamily) RGS12_usC PF16612.5 EEB05704.1 - 0.051 14.0 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 AAA_25 PF13481.6 EEB05704.1 - 0.084 12.4 0.5 2.6 7.6 0.1 2.7 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EEB05704.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EEB05704.1 - 0.1 12.9 0.8 0.47 10.8 0.8 2.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EEB05704.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 EEB05704.1 - 0.24 10.6 1.2 0.78 8.9 0.2 2.3 2 1 1 3 3 3 0 NB-ARC domain CPBP PF02517.16 EEB05705.1 - 1.1e-18 67.4 5.0 1.1e-18 67.4 5.0 2.5 1 1 0 2 2 2 1 CPBP intramembrane metalloprotease RNA_pol_L_2 PF13656.6 EEB05706.1 - 9.6e-37 124.6 0.1 1.3e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EEB05706.1 - 3.3e-16 58.5 0.0 4.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FlaC_arch PF05377.11 EEB05706.1 - 0.068 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Fasciclin PF02469.22 EEB05707.1 - 2.7e-24 85.8 2.0 5.1e-10 39.7 0.0 6.3 5 2 0 5 5 5 4 Fasciclin domain Ribosomal_S3Ae PF01015.18 EEB05708.1 - 2.1e-86 288.6 4.3 2.5e-86 288.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EEB05708.1 - 0.028 15.0 1.4 0.2 12.2 0.2 2.5 2 1 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EEB05708.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Abhydrolase_1 PF00561.20 EEB05709.1 - 7.3e-24 84.8 0.0 8.6e-18 64.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB05709.1 - 1.6e-15 58.3 0.0 1.9e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEB05709.1 - 1.1e-10 41.2 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEB05709.1 - 0.00039 20.6 0.0 0.00059 20.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EEB05709.1 - 0.0032 17.2 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 EEB05709.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 EEB05709.1 - 0.041 12.9 0.1 0.17 10.9 0.1 1.9 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 EEB05709.1 - 0.05 12.9 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.13 EEB05709.1 - 0.098 11.2 0.1 0.52 8.8 0.0 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II YEATS PF03366.16 EEB05710.1 - 2.4e-24 85.1 0.2 4e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EEB05710.1 - 8e-07 29.1 0.2 1.6e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation PDZ_1 PF12812.7 EEB05712.1 - 1.9e-43 146.4 0.0 2.2e-31 107.7 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EEB05712.1 - 8.5e-20 72.2 0.1 1.3e-17 65.1 0.0 2.8 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EEB05712.1 - 3e-15 56.3 3.0 2.5e-05 24.5 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EEB05712.1 - 3.3e-13 49.3 1.8 0.00016 21.4 0.1 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EEB05712.1 - 2.1e-10 40.8 0.0 0.0004 20.7 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Peptidase_S7 PF00949.21 EEB05712.1 - 0.0063 16.3 0.1 0.019 14.8 0.1 1.8 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.6 EEB05712.1 - 0.012 15.5 1.3 0.46 10.5 0.1 3.0 3 0 0 3 3 3 0 Tricorn protease PDZ domain Trypsin PF00089.26 EEB05712.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Trypsin DUF31 PF01732.16 EEB05712.1 - 0.026 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 EEB05712.1 - 0.13 10.8 0.1 0.26 9.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 RPN6_N PF18055.1 EEB05713.1 - 1.4e-37 128.6 3.1 3.5e-37 127.3 2.4 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EEB05713.1 - 1.5e-18 67.2 0.4 6.4e-18 65.2 0.0 2.3 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EEB05713.1 - 1.1e-13 50.7 3.4 1.1e-12 47.4 0.2 3.2 2 1 1 3 3 3 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 EEB05713.1 - 0.023 14.7 1.9 4.2 7.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EEB05713.1 - 0.026 13.9 4.8 0.74 9.1 2.7 2.3 1 1 1 2 2 2 0 MalT-like TPR region MHC_I_3 PF16497.5 EEB05713.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 MHC-I family domain TPR_16 PF13432.6 EEB05713.1 - 0.066 13.9 7.8 2.6 8.8 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05713.1 - 1.6 9.0 4.7 46 4.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05713.1 - 4.8 8.0 5.9 66 4.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SWIB PF02201.18 EEB05714.1 - 3.6e-25 87.7 0.2 1.7e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 SWIB/MDM2 domain FDF PF09532.10 EEB05715.1 - 3 8.8 10.5 4 8.4 0.7 2.6 1 1 1 2 2 2 0 FDF domain TAF4 PF05236.14 EEB05716.2 - 3.6e-61 207.4 7.0 4.7e-61 207.0 7.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4407 PF14362.6 EEB05716.2 - 0.014 14.8 2.5 0.02 14.2 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1657 PF07870.11 EEB05716.2 - 0.017 15.0 0.1 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) VIT1 PF01988.19 EEB05716.2 - 0.094 12.6 3.1 0.17 11.7 3.1 1.4 1 0 0 1 1 1 0 VIT family CoiA PF06054.11 EEB05716.2 - 0.12 11.5 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Competence protein CoiA-like family UCH PF00443.29 EEB05717.1 - 1.8e-41 142.4 0.0 3.3e-41 141.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEB05717.1 - 4.6e-09 36.5 11.7 4.6e-09 36.5 11.7 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EEB05717.1 - 2.3e-07 30.7 16.8 0.0013 18.4 0.2 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Nop PF01798.18 EEB05719.1 - 1.2e-85 286.7 0.2 1.2e-85 286.7 0.2 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEB05719.1 - 1.4e-20 73.4 1.0 6.3e-20 71.3 1.0 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Baculo_PEP_C PF04513.12 EEB05719.1 - 0.03 14.4 1.8 2.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAGA_bind PF06217.12 EEB05719.1 - 0.41 10.9 11.5 0.59 10.4 11.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EEB05719.1 - 2.6 7.8 14.7 3.6 7.3 14.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 EEB05719.1 - 2.7 7.4 9.9 4.1 6.8 9.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RGS PF00615.19 EEB05720.1 - 7.7e-06 26.2 0.1 6.1e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Bd3614-deam PF14439.6 EEB05720.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase INO80_Ies4 PF08193.11 EEB05721.1 - 3.6e-10 40.2 10.2 3.6e-10 40.2 10.2 4.8 1 1 3 4 4 4 2 INO80 complex subunit Ies4 ALG11_N PF15924.5 EEB05722.1 - 1.3e-81 273.6 0.4 2.6e-81 272.7 0.4 1.5 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EEB05722.1 - 5.2e-21 74.9 0.0 9.4e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEB05722.1 - 4e-14 53.2 0.0 1.3e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB05722.1 - 2e-09 37.7 0.1 1.4e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 DUF5615 PF18480.1 EEB05722.1 - 0.036 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ribosomal_L6 PF00347.23 EEB05723.1 - 4.7e-33 113.7 5.1 5.6e-20 71.8 2.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L29 PF00831.23 EEB05724.1 - 4e-19 68.3 2.4 4e-19 68.3 2.4 2.4 2 1 0 2 2 2 1 Ribosomal L29 protein GAS PF13851.6 EEB05724.1 - 0.0014 18.0 13.4 0.0037 16.6 5.3 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding FAM167 PF11652.8 EEB05724.1 - 0.017 15.6 0.4 0.025 15.1 0.4 1.6 1 1 0 1 1 1 0 FAM167 TAF6_C PF07571.13 EEB05724.1 - 0.025 14.9 2.6 0.97 9.8 0.1 2.3 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain HATPase_c_5 PF14501.6 EEB05724.1 - 0.067 13.1 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 GHKL domain DUF1013 PF06242.11 EEB05724.1 - 0.081 13.0 3.8 0.069 13.2 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) HAD_2 PF13419.6 EEB05724.1 - 0.13 12.4 0.6 0.17 11.9 0.6 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Prefoldin PF02996.17 EEB05724.1 - 0.19 11.6 7.6 0.87 9.5 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit PRKG1_interact PF15898.5 EEB05724.1 - 0.2 12.6 11.0 17 6.4 11.0 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Peptidase_M32 PF02074.15 EEB05724.1 - 0.33 9.7 3.1 0.39 9.4 3.1 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Nup88 PF10168.9 EEB05724.1 - 0.72 7.6 5.7 0.86 7.3 5.7 1.0 1 0 0 1 1 1 0 Nuclear pore component DivIVA PF05103.13 EEB05724.1 - 1.8 8.7 8.2 6.2 6.9 8.0 1.7 1 1 1 2 2 2 0 DivIVA protein UNC45-central PF11701.8 EEB05725.1 - 0.0002 21.4 11.8 1.6 8.6 0.6 5.4 3 2 2 5 5 5 3 Myosin-binding striated muscle assembly central Cnd1 PF12717.7 EEB05725.1 - 0.0045 17.1 3.0 0.022 14.8 0.0 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 EF-hand_6 PF13405.6 EEB05726.1 - 0.057 13.4 0.7 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain TRH PF05438.12 EEB05726.1 - 0.09 12.5 1.8 0.17 11.6 1.8 1.4 1 1 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) zf-HIT PF04438.16 EEB05727.1 - 3.7e-07 29.9 13.3 8.4e-07 28.8 13.3 1.6 1 0 0 1 1 1 1 HIT zinc finger DUF4050 PF13259.6 EEB05727.1 - 0.5 10.7 5.0 0.87 9.9 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) BCIP PF13862.6 EEB05728.1 - 8.7e-60 202.0 0.3 1e-59 201.8 0.3 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein tRNA_int_end_N2 PF12928.7 EEB05729.1 - 1.9e-24 85.6 0.0 3.7e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EEB05729.1 - 0.026 14.2 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Pet191_N PF10203.9 EEB05730.2 - 4.1e-21 75.0 11.3 5.3e-21 74.7 11.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Peptidase_M16 PF00675.20 EEB05731.1 - 9.4e-25 87.3 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEB05731.1 - 6.1e-10 39.4 0.0 1.9e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain WD40 PF00400.32 EEB05732.1 - 6.9e-12 45.7 10.0 0.00021 22.0 0.1 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05732.1 - 0.0037 17.5 0.0 6.5 7.1 0.0 4.4 2 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Rad51 PF08423.11 EEB05733.1 - 1.4e-77 260.4 0.0 1.7e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EEB05733.1 - 2.8e-07 30.3 0.0 6.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EEB05733.1 - 1.8e-06 27.5 1.7 4.9e-06 26.1 0.1 2.6 2 1 1 3 3 3 1 KaiC RecA PF00154.21 EEB05733.1 - 1.2e-05 24.9 0.0 0.028 13.9 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 EEB05733.1 - 0.0086 15.4 0.1 0.91 8.8 0.1 2.4 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain EAP30 PF04157.16 EEB05733.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Ssl1 PF04056.14 EEB05734.1 - 8.2e-80 267.2 0.1 1.1e-79 266.8 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EEB05734.1 - 9.5e-21 73.8 11.7 9.5e-21 73.8 11.7 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EEB05734.1 - 7.2e-14 52.3 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EEB05734.1 - 2.2e-05 24.8 0.1 3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 EEB05734.1 - 5.8e-05 23.2 7.7 5.8e-05 23.2 7.7 3.1 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RanBP PF00641.18 EEB05734.1 - 0.053 12.8 0.2 0.053 12.8 0.2 4.4 5 1 0 5 5 5 0 Zn-finger in Ran binding protein and others TMEM117 PF15113.6 EEB05734.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 TMEM117 protein family PUF PF00806.19 EEB05735.2 - 1.8e-40 134.4 0.2 5.2e-08 32.1 0.0 7.8 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 EEB05735.2 - 0.0079 16.6 0.1 5.3 7.4 0.0 4.1 1 1 1 3 3 3 1 CPL (NUC119) domain HNOB PF07700.15 EEB05735.2 - 0.043 13.8 0.0 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Haem-NO-binding TryThrA_C PF12319.8 EEB05735.2 - 0.14 11.7 0.2 0.33 10.4 0.2 1.6 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Mito_carr PF00153.27 EEB05736.1 - 2.4e-30 104.3 2.1 5.9e-16 58.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Beach PF02138.18 EEB05736.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain MitMem_reg PF13012.6 EEB05737.2 - 4e-33 114.2 0.1 6e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EEB05737.2 - 3.2e-10 40.0 0.0 7.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Choline_transpo PF04515.12 EEB05738.2 - 2.1e-19 69.9 25.1 2.1e-19 69.9 25.1 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF202 PF02656.15 EEB05738.2 - 0.85 10.1 0.0 0.85 10.1 0.0 5.1 5 2 0 5 5 5 0 Domain of unknown function (DUF202) UCH PF00443.29 EEB05739.2 - 3.5e-55 187.3 1.4 4.5e-55 186.9 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB05739.2 - 6.5e-21 75.3 1.6 1.2e-20 74.4 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EEB05739.2 - 0.014 14.9 5.1 1.6 8.1 3.8 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Imm48 PF15574.6 EEB05739.2 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 48 Ribosomal_L19e PF01280.20 EEB05740.1 - 3.9e-62 208.6 8.9 3.9e-62 208.6 8.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e AAA PF00004.29 EEB05741.1 - 1e-43 149.0 0.0 1.7e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB05741.1 - 1.5e-10 40.7 0.1 2.8e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EEB05741.1 - 1.8e-08 34.2 0.3 5.1e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EEB05741.1 - 6.8e-07 29.4 0.3 1.4e-05 25.1 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB05741.1 - 7.6e-07 29.7 0.0 0.00063 20.2 0.2 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EEB05741.1 - 2.4e-06 27.4 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EEB05741.1 - 8.3e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEB05741.1 - 0.00016 22.0 0.3 0.0086 16.3 0.1 2.7 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 EEB05741.1 - 0.00046 20.7 0.0 0.0016 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EEB05741.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EEB05741.1 - 0.001 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EEB05741.1 - 0.0016 17.7 0.0 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EEB05741.1 - 0.002 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EEB05741.1 - 0.0023 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EEB05741.1 - 0.0037 17.4 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EEB05741.1 - 0.0041 16.9 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EEB05741.1 - 0.0087 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB05741.1 - 0.0098 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EEB05741.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EEB05741.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EEB05741.1 - 0.038 13.3 0.1 0.17 11.2 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 EEB05741.1 - 0.039 14.2 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB05741.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EEB05741.1 - 0.086 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEB05741.1 - 0.089 12.5 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EEB05741.1 - 0.094 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EEB05741.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 EEB05741.1 - 0.099 12.4 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase PRA1 PF03208.19 EEB05742.1 - 1.5e-30 105.7 4.5 1.8e-30 105.5 4.5 1.0 1 0 0 1 1 1 1 PRA1 family protein Cnd2 PF05786.14 EEB05743.1 - 1.7e-177 592.5 13.2 2.1e-177 592.2 13.2 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EEB05743.1 - 0.0055 16.9 2.8 0.016 15.4 0.0 2.7 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal N-SET PF11764.8 EEB05744.1 - 1e-27 97.3 7.6 1.3e-22 80.8 0.1 4.5 3 1 1 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 EEB05744.1 - 3.1e-20 73.3 0.3 3.1e-20 73.3 0.3 3.8 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.8 EEB05744.1 - 3.5e-18 65.0 4.2 1.3e-17 63.1 3.4 2.3 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 EEB05744.1 - 5.4e-10 38.9 0.0 1.2e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.9 EEB05744.1 - 0.7 10.1 14.7 1.2 9.3 0.4 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 INSIG PF07281.12 EEB05745.1 - 5e-27 94.9 7.5 1.1e-26 93.8 7.5 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF2061 PF09834.9 EEB05745.1 - 6.9 7.3 8.1 32 5.1 0.4 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) Peptidase_S51 PF03575.17 EEB05746.2 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Avl9 PF09794.9 EEB05746.2 - 0.11 11.2 0.2 0.18 10.5 0.2 1.2 1 0 0 1 1 1 0 Transport protein Avl9 Fcf1 PF04900.12 EEB05747.1 - 1.8e-34 118.1 1.2 3e-34 117.3 1.2 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EEB05747.1 - 1.6e-13 51.0 0.1 3.2e-13 50.0 0.0 1.5 2 0 0 2 2 2 1 PIN like domain Cdd1 PF11731.8 EEB05747.1 - 0.053 13.8 0.2 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 Pathogenicity locus Imm-NTF2 PF15655.6 EEB05747.1 - 0.059 13.7 0.4 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 NTF2 fold immunity protein Kinesin PF00225.23 EEB05748.2 - 8.6e-110 366.8 0.4 8.6e-110 366.8 0.4 3.2 3 1 0 3 3 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEB05748.2 - 2.4e-24 85.9 0.1 2.4e-24 85.9 0.1 3.5 3 1 0 3 3 3 1 Microtubule binding Apolipoprotein PF01442.18 EEB05748.2 - 4.6e-05 23.4 7.2 4.6e-05 23.4 7.2 3.3 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain DUF812 PF05667.11 EEB05748.2 - 9e-05 21.5 20.7 9e-05 21.5 20.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF812) SF-assemblin PF06705.11 EEB05748.2 - 0.00083 18.8 8.5 0.00083 18.8 8.5 3.6 1 1 1 3 3 2 1 SF-assemblin/beta giardin Leu_zip PF15294.6 EEB05748.2 - 0.0037 16.8 13.3 0.0037 16.8 13.3 4.5 2 2 2 4 4 4 1 Leucine zipper bZIP_1 PF00170.21 EEB05748.2 - 0.012 15.7 3.1 0.012 15.7 3.1 6.0 6 0 0 6 6 6 0 bZIP transcription factor DUF1192 PF06698.11 EEB05748.2 - 0.019 15.0 1.9 12 6.1 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1944 PF09175.10 EEB05748.2 - 0.026 14.4 0.3 0.091 12.6 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Pox_G9-A16 PF03003.16 EEB05748.2 - 0.22 11.2 4.2 0.98 9.1 4.2 2.1 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 HALZ PF02183.18 EEB05748.2 - 0.23 11.7 16.3 1 9.7 2.2 6.0 4 2 2 6 6 6 0 Homeobox associated leucine zipper NOG1 PF06858.14 EEB05748.2 - 0.48 10.2 3.7 6.6 6.6 0.4 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Mto2_bdg PF12808.7 EEB05748.2 - 2.1 8.7 10.3 4.1 7.8 1.6 3.6 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region OEP PF02321.18 EEB05748.2 - 7.8 6.3 27.3 2.4 7.9 10.9 2.7 2 0 0 2 2 2 0 Outer membrane efflux protein Erp_C PF06780.11 EEB05748.2 - 8.5 6.4 9.0 1.5 8.8 3.2 2.8 3 1 0 3 3 3 0 Erp protein C-terminus Hydrolase_4 PF12146.8 EEB05749.1 - 3.4e-16 59.2 0.0 4.4e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEB05749.1 - 4.1e-10 39.7 0.3 2e-05 24.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EEB05749.1 - 2.7e-07 29.6 0.3 0.0027 16.5 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EEB05749.1 - 1.9e-06 28.0 0.0 5.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 EEB05749.1 - 5.9e-05 22.2 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EEB05749.1 - 0.00019 21.0 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EEB05749.1 - 0.00026 20.6 0.0 0.0024 17.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEB05749.1 - 0.00063 20.4 0.0 0.0009 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EEB05749.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 3) Peptidase_C48 PF02902.19 EEB05750.1 - 4.8e-24 85.4 0.0 1.2e-23 84.1 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vfa1 PF08432.10 EEB05751.1 - 9e-38 130.4 5.6 1e-37 130.2 5.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 EEB05751.1 - 0.0037 17.1 8.3 0.0052 16.6 8.3 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein ORC6 PF05460.13 EEB05751.1 - 0.015 14.6 5.4 0.016 14.5 5.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 EEB05751.1 - 0.45 9.2 4.5 0.45 9.2 4.5 1.1 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 EEB05751.1 - 0.86 9.7 8.4 1.3 9.1 8.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 EEB05751.1 - 1.1 7.5 7.1 1.3 7.2 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EEB05751.1 - 1.3 8.2 2.8 1.4 8.0 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Proteasome PF00227.26 EEB05752.1 - 8.2e-50 168.9 0.0 1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB05752.1 - 7.3e-09 35.1 0.4 1.7e-08 34.0 0.4 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADK PF00406.22 EEB05753.2 - 1.4e-43 148.5 0.1 1.7e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEB05753.2 - 5.3e-34 117.6 0.1 7.1e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEB05753.2 - 1e-09 39.0 0.0 1.4e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EEB05753.2 - 1.3e-06 28.2 0.4 0.00096 18.9 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 EEB05753.2 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 SRP54 PF00448.22 EEB05753.2 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EEB05753.2 - 0.0088 16.2 0.0 0.021 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB05753.2 - 0.038 14.3 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEB05753.2 - 0.11 12.8 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEB05753.2 - 0.17 12.2 0.3 0.6 10.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain Adeno_knob PF00541.17 EEB05755.1 - 0.00032 20.5 2.6 23 4.7 0.0 4.1 4 0 0 4 4 4 4 Adenoviral fibre protein (knob domain) Ferritin PF00210.24 EEB05755.1 - 0.012 15.5 1.6 0.42 10.6 0.1 3.4 4 0 0 4 4 4 0 Ferritin-like domain rve PF00665.26 EEB05755.1 - 0.045 14.0 0.3 6.4 7.0 0.3 3.1 1 1 0 1 1 1 0 Integrase core domain Ribosomal_S13 PF00416.22 EEB05756.2 - 6.1e-27 94.5 0.1 3.5e-14 53.3 0.5 2.1 1 1 1 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 EEB05756.2 - 0.00013 20.9 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HSA PF07529.13 EEB05757.1 - 4.7e-15 55.7 1.9 4.7e-15 55.7 1.9 2.6 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 EEB05757.1 - 1e-10 41.7 0.1 3.1e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEB05757.1 - 1.2e-05 25.4 0.2 2.5e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp PF00026.23 EEB05758.1 - 4.7e-36 124.8 0.1 6.3e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEB05758.1 - 1.7e-09 38.2 0.0 1.1e-08 35.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Erv26 PF04148.13 EEB05759.1 - 3.5e-71 239.3 6.5 4.3e-71 239.0 6.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 EEB05759.1 - 0.054 13.8 2.3 0.062 13.6 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF202 PF02656.15 EEB05759.1 - 7.6 7.1 7.3 4.3 7.9 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DEAD PF00270.29 EEB05760.1 - 2.9e-46 157.4 0.0 4.5e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB05760.1 - 1.2e-31 109.3 0.0 3.1e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB05760.1 - 0.032 14.2 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEB05760.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HSP70 PF00012.20 EEB05764.1 - 1.8e-261 868.6 12.5 2e-261 868.4 12.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB05764.1 - 3.7e-20 72.0 0.5 5.1e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EEB05764.1 - 0.0057 17.0 3.5 3.1 8.3 0.0 3.3 3 1 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 EEB05764.1 - 0.013 14.8 6.8 0.027 13.8 6.8 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 EEB05764.1 - 0.028 13.7 3.6 0.085 12.1 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FIVAR PF07554.13 EEB05764.1 - 0.085 13.6 0.7 77 4.2 0.0 3.9 3 1 0 3 3 3 0 FIVAR domain BSD PF03909.17 EEB05765.2 - 1.5e-16 60.1 0.2 1.5e-16 60.1 0.2 2.2 3 0 0 3 3 3 1 BSD domain DUF2229 PF09989.9 EEB05765.2 - 0.17 11.5 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GATA PF00320.27 EEB05766.1 - 1.3e-30 104.7 13.0 1.3e-16 59.9 3.3 2.5 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 EEB05766.1 - 0.0021 18.2 2.7 0.14 12.3 0.1 2.9 2 0 0 2 2 2 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EEB05766.1 - 0.0025 17.3 4.5 0.064 12.8 1.3 2.7 2 0 0 2 2 2 1 TFIIB zinc-binding TDP43_N PF18694.1 EEB05766.1 - 0.009 15.8 0.0 6.5 6.7 0.0 2.4 2 0 0 2 2 2 2 Transactive response DNA-binding protein N-terminal domain ArfGap PF01412.18 EEB05766.1 - 0.011 15.8 2.3 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-RRPl_C4 PF17026.5 EEB05766.1 - 0.38 10.9 3.7 2.4 8.3 0.1 3.1 2 2 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 EEB05766.1 - 0.7 9.8 4.3 3.2 7.7 0.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 EEB05766.1 - 5.9 7.0 17.6 1.7 8.7 1.3 3.6 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EEB05766.1 - 7.2 7.0 6.0 15 5.9 0.5 3.1 2 0 0 2 2 2 0 zinc-ribbon Nuf2 PF03800.14 EEB05767.2 - 2e-43 147.8 0.9 2e-43 147.8 0.9 2.2 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EEB05767.2 - 7.4e-25 87.3 18.8 7.4e-25 87.3 18.8 4.3 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Acyl-CoA_dh_C PF12806.7 EEB05767.2 - 1.6 8.9 7.3 16 5.7 0.3 3.7 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like DUF948 PF06103.11 EEB05767.2 - 2.4 8.5 15.3 1.2 9.4 1.8 4.3 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) ATP-synt_G PF04718.15 EEB05767.2 - 2.6 8.9 0.0 2.6 8.9 0.0 3.4 3 2 0 3 3 3 0 Mitochondrial ATP synthase g subunit Baculo_PEP_C PF04513.12 EEB05767.2 - 3.2 7.8 14.0 10 6.2 0.1 4.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EEB05767.2 - 5.1 7.6 49.4 0.038 14.5 5.5 4.6 3 1 2 5 5 5 0 Apg6 coiled-coil region Spc7 PF08317.11 EEB05767.2 - 5.1 5.9 43.4 0.05 12.5 13.9 3.0 3 1 1 4 4 4 0 Spc7 kinetochore protein Peptidase_C12 PF01088.21 EEB05768.1 - 1.8e-44 152.0 0.0 2.1e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 BCA_ABC_TP_C PF12399.8 EEB05768.1 - 0.063 13.2 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Nipped-B_C PF12830.7 EEB05769.2 - 2.2e-38 132.1 4.0 2.2e-38 132.1 4.0 4.4 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EEB05769.2 - 1.1e-07 32.0 8.3 1.5e-06 28.4 0.1 4.1 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EEB05769.2 - 0.011 15.9 3.6 52 4.5 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat RsfS PF02410.15 EEB05770.1 - 3.3e-09 37.1 0.0 1.1e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 EEB05770.1 - 0.0054 15.8 0.2 0.0087 15.1 0.2 1.3 1 0 0 1 1 1 1 mRNA stabilisation FF PF01846.19 EEB05770.1 - 0.038 14.2 0.3 0.22 11.7 0.1 2.5 2 0 0 2 2 2 0 FF domain DEAD PF00270.29 EEB05771.1 - 1.7e-50 171.3 0.1 1.9e-48 164.6 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB05771.1 - 3e-25 88.7 0.1 7.1e-24 84.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EEB05771.1 - 1.3e-19 70.2 0.7 5.9e-19 68.1 0.7 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Ribosomal_L23 PF00276.20 EEB05772.1 - 1.5e-14 54.1 0.3 2.5e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Adap_comp_sub PF00928.21 EEB05773.1 - 3.3e-77 259.4 0.6 4.2e-77 259.1 0.6 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEB05773.1 - 1.2e-06 28.5 1.2 1.2e-06 28.5 1.2 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Ran-binding PF05508.11 EEB05774.2 - 9.7e-98 327.0 0.4 1.2e-97 326.7 0.4 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Vps53_N PF04100.12 EEB05774.2 - 0.078 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Copper-fist PF00649.18 EEB05775.1 - 1.9e-18 65.6 2.8 1.9e-18 65.6 2.8 2.3 2 0 0 2 2 2 1 Copper fist DNA binding domain Arrestin_C PF02752.22 EEB05776.1 - 1.5e-21 77.3 0.6 4.3e-19 69.3 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEB05776.1 - 4.1e-16 59.3 0.0 9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EEB05776.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF3337 PF11816.8 EEB05778.1 - 6.4e-33 114.0 0.0 1.6e-32 112.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EEB05778.1 - 1.5e-12 47.8 13.5 0.0024 18.7 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05778.1 - 0.0018 18.5 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB05778.1 - 0.1 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Dcc1 PF09724.9 EEB05779.1 - 4.6e-62 210.3 3.9 5.4e-62 210.0 3.9 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RICTOR_M PF14666.6 EEB05779.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Bcr-Abl_Oligo PF09036.10 EEB05779.1 - 0.12 12.4 1.8 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Nod1 PF17114.5 EEB05780.1 - 4.8e-53 179.2 0.7 1.6e-52 177.5 0.7 2.0 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 RhoGEF PF00621.20 EEB05780.1 - 1.6e-25 90.4 0.2 4.4e-25 89.0 0.2 1.8 1 0 0 1 1 1 1 RhoGEF domain Proteasome PF00227.26 EEB05781.1 - 1.3e-58 197.6 0.3 1.6e-58 197.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB05781.1 - 4.5e-13 48.6 0.1 8.5e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FF PF01846.19 EEB05782.1 - 1.4e-16 60.4 3.8 3.3e-13 49.6 0.0 4.0 4 0 0 4 4 4 2 FF domain WW PF00397.26 EEB05782.1 - 1.2e-11 44.4 4.1 1.8e-07 31.1 1.0 2.5 2 0 0 2 2 2 2 WW domain Tht1 PF04163.12 EEB05783.1 - 9e-39 133.6 14.7 1.2e-38 133.2 14.7 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein DAO_C PF16901.5 EEB05783.1 - 0.032 14.1 0.2 0.062 13.2 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase IL6 PF00489.17 EEB05783.1 - 0.25 10.9 7.4 7 6.2 0.0 2.8 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family MitMem_reg PF13012.6 EEB05783.1 - 1 9.8 12.3 12 6.3 12.3 2.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function IF-2B PF01008.17 EEB05783.1 - 1.8 7.7 11.7 4 6.6 3.7 2.3 1 1 1 2 2 2 0 Initiation factor 2 subunit family Cytochrom_B562 PF07361.11 EEB05783.1 - 5.7 7.7 9.6 12 6.7 0.3 3.1 2 1 1 3 3 3 0 Cytochrome b562 GATase PF00117.28 EEB05784.2 - 5.7e-10 39.3 0.0 7.3e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pantoate_transf PF02548.15 EEB05785.1 - 2e-111 371.6 0.3 3.3e-111 370.8 0.3 1.3 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EEB05785.1 - 1.5e-07 31.2 0.1 2.8e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEMT PF04191.13 EEB05786.2 - 4.6e-30 104.2 0.7 9e-30 103.2 0.7 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase NUC153 PF08159.12 EEB05787.1 - 1.4e-16 60.0 11.8 2.7e-13 49.5 0.5 3.9 3 0 0 3 3 3 3 NUC153 domain Methyltransf_2 PF00891.18 EEB05787.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CDC27 PF09507.10 EEB05788.1 - 3.6e-38 132.1 28.5 2.4e-23 83.2 23.4 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 RRP7 PF12923.7 EEB05788.1 - 8.9 6.5 16.4 0.044 13.9 4.9 2.7 1 1 2 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Pterin_bind PF00809.22 EEB05789.1 - 9.5e-79 264.5 1.5 2e-78 263.5 0.1 2.0 2 0 0 2 2 2 1 Pterin binding enzyme FolB PF02152.18 EEB05789.1 - 2.7e-41 140.6 3.8 3e-21 76.1 1.9 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 EEB05789.1 - 3.4e-34 117.7 0.0 1.7e-33 115.5 0.0 2.2 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Anp1 PF03452.14 EEB05790.1 - 6.8e-110 366.6 0.0 9.7e-110 366.1 0.0 1.2 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EEB05790.1 - 0.0037 17.1 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DnaJ PF00226.31 EEB05791.1 - 4.5e-17 61.9 0.0 1.1e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_2 PF13923.6 EEB05792.1 - 1.2e-07 31.5 17.6 1.2e-07 31.5 17.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EEB05792.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 EEB05792.1 - 7.5e-05 22.5 18.8 0.00016 21.4 14.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB05792.1 - 0.00021 21.6 26.8 0.00022 21.5 18.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EEB05792.1 - 0.00039 20.2 18.9 0.00039 20.2 18.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB05792.1 - 0.00053 19.9 14.3 0.00053 19.9 14.3 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEB05792.1 - 0.00072 19.5 17.4 0.00072 19.5 17.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EEB05792.1 - 0.0015 18.4 8.9 0.0032 17.3 8.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein RNF220 PF15926.5 EEB05792.1 - 0.002 17.8 6.9 0.002 17.8 6.9 3.3 2 1 1 3 3 3 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_4 PF15227.6 EEB05792.1 - 0.0021 18.2 18.9 0.0021 18.2 18.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PRP21_like_P PF12230.8 EEB05792.1 - 0.012 15.5 0.6 0.04 13.8 0.6 2.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-CpG_bind_C PF12269.8 EEB05792.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.5 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf_UBZ PF18439.1 EEB05792.1 - 0.037 13.6 0.3 0.037 13.6 0.3 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Prok-RING_4 PF14447.6 EEB05792.1 - 0.1 12.5 24.4 6 6.8 19.6 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 EEB05792.1 - 0.25 11.7 0.2 0.25 11.7 0.2 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 EEB05792.1 - 7.5 7.1 10.7 26 5.4 0.2 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 EEB05792.1 - 7.7 6.7 13.3 2.1 8.6 9.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 TRAPPC-Trs85 PF12739.7 EEB05793.1 - 2.3e-85 287.0 1.8 2.9e-85 286.7 1.8 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_14 PF13428.6 EEB05793.1 - 0.17 12.8 0.3 0.69 10.9 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SNAP PF14938.6 EEB05793.1 - 0.26 10.7 1.2 8.7 5.7 0.1 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP VHS PF00790.19 EEB05794.1 - 1.2e-28 99.7 0.7 2.8e-28 98.6 0.7 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EEB05794.1 - 1e-16 60.2 0.0 1.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB05794.1 - 2.7e-15 56.0 0.1 5.6e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB05794.1 - 1.7e-13 50.0 0.1 5.7e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EEB05794.1 - 6.8e-05 23.1 0.5 6.8e-05 23.1 0.5 2.6 3 0 0 3 3 3 1 GAT domain UIM PF02809.20 EEB05794.1 - 0.0042 16.9 4.2 0.013 15.3 4.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif RasGEF_N PF00618.20 EEB05794.1 - 0.059 13.6 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif Med26 PF08711.11 EEB05794.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Thioredoxin PF00085.20 EEB05795.1 - 3.7e-19 68.6 0.3 7.8e-19 67.6 0.3 1.6 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EEB05795.1 - 1.6e-18 66.7 0.0 5.4e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.6 EEB05795.1 - 0.00047 20.6 0.0 0.0051 17.3 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 EEB05795.1 - 0.0028 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.16 EEB05795.1 - 0.0061 15.5 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.6 EEB05795.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like MSP1_C PF07462.11 EEB05795.1 - 0.013 14.2 1.2 0.016 13.9 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus OST3_OST6 PF04756.13 EEB05795.1 - 0.034 13.5 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEB05795.1 - 0.069 13.5 0.1 0.94 9.8 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like DUF2868 PF11067.8 EEB05795.1 - 0.12 11.9 0.9 7.9 5.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Metallophos PF00149.28 EEB05796.2 - 7.1e-37 127.9 0.1 9.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEB05796.2 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 EEB05796.2 - 0.13 12.7 1.0 0.27 11.7 1.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain IML1 PF12257.8 EEB05797.1 - 3.3e-109 364.4 0.2 5e-109 363.8 0.2 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EEB05797.1 - 4e-24 84.5 0.1 1e-23 83.2 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PEMT PF04191.13 EEB05798.1 - 4.7e-60 200.6 13.9 6.5e-36 122.9 1.4 3.4 4 0 0 4 4 4 2 Phospholipid methyltransferase HECW_N PF16562.5 EEB05798.1 - 0.00038 20.3 0.1 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EEB05798.1 - 0.0016 18.9 0.2 0.012 16.1 0.2 2.3 1 1 0 1 1 1 1 SKICH domain RE_NgoFVII PF09565.10 EEB05799.1 - 0.0025 17.2 1.3 0.0038 16.6 1.3 1.2 1 0 0 1 1 1 1 NgoFVII restriction endonuclease V-SNARE_C PF12352.8 EEB05799.1 - 0.33 11.3 3.2 5.3 7.4 0.4 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF5563 PF17718.1 EEB05799.1 - 0.84 9.2 5.5 0.12 12.0 1.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5563) Thi4 PF01946.17 EEB05800.1 - 4.9e-113 376.1 0.1 6.3e-113 375.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EEB05800.1 - 5.8e-09 36.0 2.8 5e-07 29.6 1.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEB05800.1 - 4.3e-06 26.9 0.7 2.1e-05 24.6 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EEB05800.1 - 2.1e-05 23.8 3.3 0.0031 16.7 1.2 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EEB05800.1 - 3.9e-05 23.0 0.1 6.2e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEB05800.1 - 0.00027 20.1 1.2 0.00068 18.8 0.4 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EEB05800.1 - 0.00032 20.2 0.4 0.00042 19.8 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEB05800.1 - 0.0041 17.1 1.1 0.03 14.3 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EEB05800.1 - 0.0053 15.5 0.7 0.011 14.5 0.7 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EEB05800.1 - 0.13 11.3 0.6 1.5 7.8 0.1 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A DUF4569 PF15133.6 EEB05800.1 - 0.23 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Pyr_redox_3 PF13738.6 EEB05800.1 - 0.25 10.6 0.9 0.62 9.3 1.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRMT5_C PF17286.2 EEB05801.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PALP PF00291.25 EEB05802.1 - 2.4e-76 256.9 0.7 3.6e-76 256.4 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EEB05802.1 - 7.5e-39 131.4 0.0 8.3e-20 70.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DPM3 PF08285.11 EEB05803.1 - 6.4e-18 64.7 0.1 7.1e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) YqhR PF11085.8 EEB05803.1 - 0.049 13.6 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF1523 PF07509.11 EEB05803.1 - 0.087 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Methyltransf_33 PF10017.9 EEB05804.1 - 1.2e-76 257.8 0.5 1.2e-76 257.8 0.5 1.6 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EEB05804.1 - 2e-27 96.4 0.5 3.9e-25 88.9 0.6 3.0 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EEB05804.1 - 1.6e-05 25.4 1.2 4.9e-05 23.8 1.2 1.8 1 1 0 1 1 1 1 DinB superfamily Methyltransf_8 PF05148.15 EEB05804.1 - 0.001 19.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_31 PF13847.6 EEB05804.1 - 0.073 12.9 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EEB05804.1 - 0.12 13.0 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 EEB05805.1 - 0.0002 21.5 0.1 25 5.2 0.0 5.5 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EEB05805.1 - 0.0022 18.0 0.2 3.2 7.9 0.1 3.2 2 1 1 3 3 3 2 Pentatricopeptide repeat domain Questin_oxidase PF14027.6 EEB05806.1 - 3.6e-11 43.2 0.0 4.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Mito_carr PF00153.27 EEB05807.1 - 4.5e-56 186.8 1.4 9.6e-22 76.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB05807.1 - 0.03 13.5 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Phage_holin_3_1 PF05106.12 EEB05807.1 - 0.066 13.7 0.0 70 4.0 0.0 3.3 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Mt_ATP-synt_B PF05405.14 EEB05808.1 - 8.4e-36 123.1 4.0 1e-35 122.7 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) T2SSS_2 PF16549.5 EEB05808.1 - 0.095 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS) pilotin, S protein LAGLIDADG_WhiA PF14527.6 EEB05808.1 - 0.14 12.2 0.5 0.47 10.6 0.1 2.0 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain TFCD_C PF12612.8 EEB05808.1 - 0.18 11.6 3.6 2.2 8.1 3.6 2.1 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal CobD_Cbib PF03186.13 EEB05808.1 - 6.1 6.0 8.8 6.1 6.0 2.4 2.1 1 1 1 2 2 2 0 CobD/Cbib protein BLM10_mid PF16507.5 EEB05810.2 - 1.6e-138 462.6 8.1 2.9e-138 461.8 8.1 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EEB05810.2 - 0.0038 17.1 0.1 0.026 14.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 EEB05810.2 - 0.0087 15.6 2.6 0.058 13.0 0.2 3.0 2 0 0 2 2 2 1 CLASP N terminal CRAL_TRIO_2 PF13716.6 EEB05810.2 - 0.026 14.7 0.0 0.17 12.1 0.0 2.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2660 PF10859.8 EEB05810.2 - 0.14 12.7 0.1 34 5.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2660) CBF PF03914.17 EEB05811.2 - 5.9e-30 104.5 0.9 1.1e-29 103.6 0.4 1.7 2 0 0 2 2 2 1 CBF/Mak21 family PGI PF00342.19 EEB05812.1 - 9.7e-236 783.0 0.0 1.1e-235 782.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Arm PF00514.23 EEB05813.1 - 1.3e-92 301.3 16.1 5.9e-13 48.4 0.0 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EEB05813.1 - 7.7e-25 87.2 6.8 5.5e-24 84.4 7.3 2.2 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 EEB05813.1 - 1.3e-24 86.2 0.8 1e-08 35.5 0.0 6.3 6 0 0 6 6 6 3 HEAT-like repeat Arm_3 PF16186.5 EEB05813.1 - 2.4e-21 75.0 0.1 5.1e-20 70.8 0.5 2.7 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 EEB05813.1 - 2.6e-19 69.4 0.0 1.3e-06 28.7 0.0 5.2 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.22 EEB05813.1 - 4.9e-18 63.7 0.7 0.00073 19.6 0.0 7.8 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.20 EEB05813.1 - 1.1e-06 27.5 0.0 6.8e-05 21.6 0.0 3.0 2 1 1 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EEB05813.1 - 1.7e-06 28.1 0.0 0.018 15.1 0.0 4.2 3 3 2 5 5 5 1 V-ATPase subunit H CTNNBL PF08216.11 EEB05813.1 - 5.4e-05 23.3 0.2 0.87 9.8 0.0 4.8 6 0 0 6 6 6 2 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 EEB05813.1 - 0.0062 16.5 0.1 0.067 13.2 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EEB05813.1 - 0.0086 16.7 0.6 28 5.8 0.0 4.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 EEB05813.1 - 0.11 10.9 0.1 2.4 6.6 0.0 2.9 3 2 0 3 3 3 0 Proteasome non-ATPase 26S subunit RNase_T PF00929.24 EEB05814.1 - 4.7e-17 63.0 0.0 1.4e-16 61.5 0.0 1.8 2 1 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EEB05814.1 - 0.00022 21.0 0.0 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease Med21 PF11221.8 EEB05815.1 - 2.3e-33 115.5 5.2 3.4e-33 114.9 5.2 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EEB05815.1 - 1.1e-05 25.5 3.5 1.1e-05 25.5 3.5 2.1 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF2046 PF09755.9 EEB05815.1 - 0.0015 17.8 3.7 0.0018 17.6 3.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DHR10 PF18595.1 EEB05815.1 - 0.0025 17.9 7.4 0.0041 17.2 7.4 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain THOC7 PF05615.13 EEB05815.1 - 0.0033 17.7 2.3 0.0044 17.3 2.3 1.3 1 1 0 1 1 1 1 Tho complex subunit 7 DivIC PF04977.15 EEB05815.1 - 0.0035 17.1 6.0 0.01 15.6 6.0 1.8 1 0 0 1 1 1 1 Septum formation initiator CLZ PF16526.5 EEB05815.1 - 0.0043 17.4 3.6 0.032 14.6 3.9 2.0 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 EEB05815.1 - 0.005 16.8 6.7 0.0081 16.1 6.7 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 EEB05815.1 - 0.011 15.4 8.1 0.011 15.4 8.1 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease AAA_23 PF13476.6 EEB05815.1 - 0.027 15.0 1.7 0.029 14.9 1.7 1.2 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 EEB05815.1 - 0.034 14.8 3.6 0.034 14.8 3.6 1.5 2 0 0 2 2 1 0 Initiation control protein YabA MCU PF04678.13 EEB05815.1 - 0.037 14.1 0.7 0.053 13.6 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4140 PF13600.6 EEB05815.1 - 0.051 14.0 2.6 0.054 13.9 1.8 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 EEB05815.1 - 0.065 12.3 4.1 0.083 12.0 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliD_C PF07195.12 EEB05815.1 - 0.12 11.8 2.3 0.13 11.6 2.3 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.8 EEB05815.1 - 0.13 11.5 7.6 0.19 11.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 EEB05815.1 - 0.17 12.2 3.8 0.81 10.0 1.7 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TSC22 PF01166.18 EEB05815.1 - 0.35 11.2 4.9 0.42 11.0 3.6 1.8 2 0 0 2 2 1 0 TSC-22/dip/bun family FUSC PF04632.12 EEB05815.1 - 0.51 8.8 2.3 0.61 8.6 2.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family IFT20 PF14931.6 EEB05815.1 - 1.8 8.8 13.6 0.89 9.7 10.9 1.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 F1F0-ATPsyn_F PF10791.9 EEB05816.1 - 9.4e-29 99.7 0.3 1.2e-28 99.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi TFIIE-A_C PF11521.8 EEB05817.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.0 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha UPF0242 PF06785.11 EEB05817.1 - 1.7 8.7 5.7 3.3 7.8 5.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L32p PF01783.23 EEB05818.1 - 1.4e-13 50.9 4.6 1.7e-13 50.6 4.6 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 EEB05818.1 - 0.0019 17.7 0.3 0.0029 17.1 0.3 1.3 1 0 0 1 1 1 1 RecR protein Prok-RING_4 PF14447.6 EEB05818.1 - 0.03 14.2 3.1 3.2 7.7 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEB05818.1 - 0.036 13.9 4.1 0.24 11.3 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EEB05818.1 - 0.12 12.3 0.7 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 EEB05818.1 - 1.7 9.2 3.5 37 4.9 0.3 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Pkinase PF00069.25 EEB05819.2 - 1.5e-72 244.2 0.0 2.1e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05819.2 - 1e-47 162.6 0.0 1.6e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EEB05819.2 - 9.1e-23 80.4 0.0 2.4e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EEB05819.2 - 8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEB05819.2 - 3.8e-05 22.6 0.3 3.8e-05 22.6 0.3 2.5 2 1 0 2 2 2 1 Fungal protein kinase DSHCT PF08148.12 EEB05819.2 - 0.00019 21.1 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.23 EEB05819.2 - 0.065 13.1 0.1 0.36 10.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEB05819.2 - 0.078 12.3 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB05819.2 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Gpi16 PF04113.14 EEB05820.1 - 4.9e-148 494.0 0.0 6.7e-148 493.6 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component PPR_2 PF13041.6 EEB05821.1 - 2e-33 114.3 16.3 2.5e-11 43.6 0.0 11.9 8 3 6 14 14 14 9 PPR repeat family PPR_3 PF13812.6 EEB05821.1 - 6.8e-29 99.7 0.5 3e-05 24.0 0.0 8.6 7 2 2 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 EEB05821.1 - 4.6e-28 95.5 12.1 0.00011 22.2 0.0 12.2 13 0 0 13 13 13 5 PPR repeat PPR_1 PF12854.7 EEB05821.1 - 1.5e-16 59.8 11.7 4e-07 29.6 0.0 7.6 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 EEB05821.1 - 5.7e-15 55.2 5.7 1.4e-09 37.7 0.1 4.1 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EEB05821.1 - 3.2e-06 27.5 1.7 25 6.0 0.0 7.4 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05821.1 - 2.1e-05 24.9 0.5 13 6.4 0.0 6.0 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB05821.1 - 4.2e-05 23.3 1.1 13 6.1 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3368 PF11848.8 EEB05821.1 - 0.011 15.5 0.1 0.11 12.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) TPR_8 PF13181.6 EEB05821.1 - 0.014 15.5 7.9 62 4.2 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05821.1 - 0.11 12.6 12.8 55 4.2 0.2 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEB05821.1 - 0.34 11.6 1.1 1.1e+02 3.9 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat G-patch PF01585.23 EEB05822.1 - 1.7e-05 24.6 0.2 4.8e-05 23.2 0.1 1.9 1 1 1 2 2 2 1 G-patch domain Tti2 PF10521.9 EEB05823.2 - 2e-10 40.7 1.5 9.7e-05 22.0 0.1 2.8 2 1 1 3 3 3 2 Tti2 family Mrpl_C PF18502.1 EEB05823.2 - 2.2 8.6 5.8 0.37 11.1 0.2 2.4 3 0 0 3 3 3 0 54S ribosomal protein L8 C-terminal domain Snf7 PF03357.21 EEB05824.1 - 8.9e-23 80.7 4.8 6e-22 78.0 5.8 1.7 2 0 0 2 2 2 1 Snf7 IDEAL PF08858.10 EEB05824.1 - 0.0019 17.9 1.8 0.14 11.9 0.3 2.8 2 0 0 2 2 2 2 IDEAL domain Macscav_rec PF03523.13 EEB05824.1 - 0.11 12.4 1.2 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 Macrophage scavenger receptor PEP-utilisers_N PF05524.13 EEB05824.1 - 3.8 7.7 5.1 8.5 6.6 0.2 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Tex_N PF09371.10 EEB05824.1 - 8.7 6.0 9.8 6.3 6.4 0.8 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain TRAPPC-Trs85 PF12739.7 EEB05825.1 - 2.9e-86 290.0 8.5 4e-86 289.5 8.5 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Kinesin PF00225.23 EEB05826.1 - 3.7e-94 315.4 1.7 3.7e-94 315.4 1.7 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEB05826.1 - 2.6e-21 76.1 0.1 5.3e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding DUF812 PF05667.11 EEB05826.1 - 0.00058 18.9 8.7 0.00077 18.5 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 EEB05826.1 - 0.044 12.7 7.2 0.097 11.5 5.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Troponin PF00992.20 EEB05826.1 - 1 9.7 7.4 0.51 10.6 4.3 1.8 1 1 1 2 2 2 0 Troponin UPF0242 PF06785.11 EEB05826.1 - 2.6 8.1 8.9 0.61 10.2 2.3 2.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PET117 PF15786.5 EEB05827.1 - 1.4e-16 60.5 0.3 1.6e-16 60.3 0.3 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HEPN_AbiV PF18728.1 EEB05827.1 - 0.099 12.8 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 AbiV CCB1 PF12046.8 EEB05827.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B ThiF PF00899.21 EEB05828.2 - 2.1e-104 348.2 0.0 2.8e-71 239.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EEB05828.2 - 4.8e-95 318.2 0.0 7.7e-95 317.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EEB05828.2 - 2.6e-33 114.6 0.1 6e-33 113.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EEB05828.2 - 2.2e-27 95.0 0.1 4.9e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EEB05828.2 - 1.1e-24 86.4 0.0 3e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 EEB05828.2 - 0.0039 17.2 0.6 0.2 11.7 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase RNase_PH PF01138.21 EEB05829.2 - 1.3e-32 113.1 0.1 2e-32 112.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FA_synthesis PF02504.15 EEB05829.2 - 0.047 12.7 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein UQ_con PF00179.26 EEB05830.1 - 2.6e-37 127.6 0.1 3.3e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GCP_N_terminal PF17681.1 EEB05831.1 - 2.4e-13 50.4 1.6 2.4e-13 50.4 1.6 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEB05831.1 - 5.4e-08 32.7 3.2 1.3e-07 31.4 3.2 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF4456 PF14644.6 EEB05831.1 - 0.0067 16.1 0.2 0.017 14.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) TSLP PF15216.6 EEB05831.1 - 0.051 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Thymic stromal lymphopoietin Utp21 PF04192.12 EEB05831.1 - 0.61 9.6 2.9 1.1 8.7 0.4 2.5 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain SF3b10 PF07189.11 EEB05832.1 - 7.9e-33 112.4 0.0 8.9e-33 112.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) tRNA_synthFbeta PF17759.1 EEB05832.1 - 0.091 12.2 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain MCM PF00493.23 EEB05833.1 - 9.1e-104 345.4 0.3 1.3e-103 344.9 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEB05833.1 - 8e-39 132.4 0.2 1.7e-38 131.3 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EEB05833.1 - 3.3e-27 94.9 1.9 3.3e-27 94.9 1.9 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EEB05833.1 - 1.7e-26 92.4 1.4 5.1e-26 90.9 1.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEB05833.1 - 8.6e-23 80.9 1.1 3.5e-22 79.0 0.2 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEB05833.1 - 4.4e-08 32.8 0.0 5.1e-07 29.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EEB05833.1 - 0.001 18.9 0.0 0.0036 17.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB05833.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EEB05833.1 - 0.0067 16.4 0.1 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.14 EEB05833.1 - 0.03 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain zf-RRN7 PF11781.8 EEB05833.1 - 0.22 11.2 0.3 0.48 10.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SPACA9 PF15120.6 EEB05834.2 - 0.096 12.5 3.1 0.59 9.9 2.9 2.4 2 1 0 2 2 2 0 Sperm acrosome-associated protein 9 Suf PF05843.14 EEB05835.1 - 1.4e-15 58.0 15.1 6.7e-05 23.0 0.2 6.1 4 2 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EEB05835.1 - 5e-10 38.8 0.8 0.037 14.2 0.0 6.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05835.1 - 5.8e-09 36.0 19.0 8.5 7.5 0.0 10.8 7 3 5 12 12 12 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05835.1 - 6.7e-08 32.7 6.1 0.27 11.6 0.0 6.2 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05835.1 - 4.6e-07 30.2 5.5 0.0013 19.2 0.1 5.1 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05835.1 - 8e-06 25.6 15.5 1.4 9.2 0.2 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EEB05835.1 - 2.6e-05 24.2 9.5 0.77 9.7 0.1 5.9 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 EEB05835.1 - 4.5e-05 22.7 12.4 0.35 10.0 0.1 5.0 3 2 3 6 6 6 3 NRDE-2, necessary for RNA interference SNAP PF14938.6 EEB05835.1 - 0.0052 16.2 0.1 10 5.5 0.0 3.9 4 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 EEB05835.1 - 0.056 13.1 0.1 4 7.1 0.0 3.2 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Mad3_BUB1_I_2 PF17014.5 EEB05835.1 - 0.07 13.2 0.1 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Putative Mad3/BUB1 like region 1 protein PPR PF01535.20 EEB05835.1 - 0.11 12.8 0.1 1.9 8.9 0.0 3.3 2 0 0 2 2 2 0 PPR repeat Cytochrom_C_2 PF01322.20 EEB05835.1 - 0.14 13.0 1.2 18 6.3 0.0 3.1 2 2 0 2 2 2 0 Cytochrome C' TPR_16 PF13432.6 EEB05835.1 - 0.66 10.7 8.9 11 6.8 0.1 5.1 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05835.1 - 0.95 10.2 13.2 9.2 7.1 0.1 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEB05835.1 - 7.1 6.6 9.6 58 3.7 0.1 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 EEB05836.1 - 1.7e-27 95.5 0.0 3.2e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TPR_1 PF00515.28 EEB05837.2 - 5.1e-50 165.4 36.6 2.5e-08 33.4 0.1 11.0 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05837.2 - 2.5e-43 142.7 32.0 7.5e-06 25.7 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05837.2 - 4.1e-31 104.6 24.2 4.8e-05 23.2 0.1 10.4 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05837.2 - 1.1e-27 94.4 20.2 0.0053 17.0 0.0 10.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05837.2 - 2.1e-24 85.9 10.7 8.4e-06 26.3 0.5 7.2 2 1 5 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EEB05837.2 - 4.5e-22 77.5 31.2 1.1e-05 25.1 0.6 9.6 6 2 3 9 9 9 5 TPR repeat TPR_14 PF13428.6 EEB05837.2 - 5.5e-22 76.6 10.4 0.0023 18.6 0.0 9.1 2 2 7 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05837.2 - 2.3e-20 72.7 26.7 0.0004 20.6 0.5 8.3 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05837.2 - 2e-19 69.8 20.2 0.0011 19.5 0.1 8.2 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05837.2 - 7.5e-19 67.1 17.6 0.061 14.0 0.6 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEB05837.2 - 7.3e-15 53.8 15.0 0.22 11.6 0.1 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEB05837.2 - 8.2e-15 54.7 12.8 0.0016 18.5 0.3 6.3 3 2 3 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB05837.2 - 1.8e-07 31.2 18.1 9.5e-07 29.0 2.8 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EEB05837.2 - 0.0084 15.1 3.6 1.3 7.9 0.0 3.2 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 EEB05837.2 - 0.32 11.4 4.6 17 5.8 0.2 3.6 2 1 2 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 EEB05837.2 - 2.3 8.2 18.9 10 6.1 0.2 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEB05837.2 - 2.9 8.1 12.9 23 5.2 0.1 5.2 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat RFC1 PF08519.12 EEB05839.1 - 9.1e-53 178.6 0.6 3.3e-52 176.8 0.0 2.2 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EEB05839.1 - 1.1e-12 48.1 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EEB05839.1 - 4.5e-10 40.0 0.0 9.3e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEB05839.1 - 5.3e-05 23.2 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EEB05839.1 - 0.00013 22.3 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB05839.1 - 0.0066 16.9 0.0 0.0066 16.9 0.0 2.5 3 1 0 3 3 2 1 AAA ATPase domain NACHT PF05729.12 EEB05839.1 - 0.0066 16.4 0.0 0.054 13.4 0.0 2.2 1 1 0 1 1 1 1 NACHT domain DNA_pol3_delta PF06144.13 EEB05839.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 EEB05839.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EEB05839.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEB05839.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 EEB05839.1 - 0.048 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EEB05839.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EEB05839.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain BRCT_2 PF16589.5 EEB05839.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain RabGAP-TBC PF00566.18 EEB05840.1 - 9.3e-41 139.8 1.4 9.3e-41 139.8 1.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 EEB05840.1 - 2.8e-05 23.9 0.6 0.0004 20.3 0.1 2.4 2 0 0 2 2 2 1 GRAM domain Hist_deacetyl PF00850.19 EEB05840.1 - 0.051 13.0 0.2 0.23 10.9 0.0 2.1 3 0 0 3 3 3 0 Histone deacetylase domain EF-hand_7 PF13499.6 EEB05840.1 - 0.066 13.7 0.1 0.26 11.8 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_M22 PF00814.25 EEB05841.1 - 4e-69 233.3 0.0 4.7e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.6 EEB05841.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 YycC-like protein Biotin_lipoyl PF00364.22 EEB05842.2 - 7e-21 73.8 0.5 1.4e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EEB05842.2 - 2.6e-07 30.8 0.0 9e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EEB05842.2 - 6.8e-07 29.0 2.4 0.056 13.3 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 EEB05842.2 - 0.0001 23.0 3.8 0.025 15.3 0.4 3.1 3 1 1 4 4 4 2 HlyD family secretion protein 2-oxoacid_dh PF00198.23 EEB05842.2 - 0.0008 18.9 0.0 0.0035 16.8 0.0 1.9 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HlyD_D23 PF16576.5 EEB05842.2 - 0.018 14.3 0.1 0.11 11.7 0.1 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion STAT_bind PF02864.15 EEB05842.2 - 0.1 13.1 0.3 5.5 7.6 0.0 3.3 3 1 0 3 3 3 0 STAT protein, DNA binding domain QRPTase_N PF02749.16 EEB05842.2 - 0.14 12.2 0.1 3.1 7.9 0.0 2.5 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Big_10 PF17964.1 EEB05842.2 - 0.17 11.8 2.6 14 5.6 1.8 2.5 2 1 0 2 2 2 0 Bacterial Ig domain DUF2457 PF10446.9 EEB05843.1 - 1e-13 51.3 58.5 5.8e-13 48.8 53.8 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2457) Kisspeptin PF15152.6 EEB05843.1 - 0.74 10.6 3.5 4.2 8.2 0.1 3.3 3 0 0 3 3 3 0 Kisspeptin Nop14 PF04147.12 EEB05843.1 - 2.1 6.5 20.6 2.9 6.0 20.6 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 EEB05843.1 - 4.3 5.0 10.4 6.9 4.3 10.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 EEB05843.1 - 5.5 5.0 26.1 8.4 4.4 26.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EEB05843.1 - 6.4 4.9 15.0 1.8 6.8 11.8 1.7 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 EEB05843.1 - 9.1 5.5 20.5 20 4.3 20.5 1.5 1 0 0 1 1 1 0 NOA36 protein Rxt3 PF08642.10 EEB05844.1 - 1.6e-18 67.7 0.3 2.2e-11 44.6 0.2 2.6 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 EEB05844.1 - 8.5e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 LCCL domain NAD_binding_4 PF07993.12 EEB05845.1 - 4.8e-72 242.2 0.0 7.5e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EEB05845.1 - 1.3e-67 228.2 0.0 1.8e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EEB05845.1 - 3.8e-10 40.0 0.0 9.5e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EEB05845.1 - 4.2e-09 36.2 0.0 7.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 EEB05845.1 - 1.2e-08 34.2 0.1 2.7e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EEB05845.1 - 9.4e-08 32.9 0.4 1.5e-06 29.1 0.0 3.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EEB05845.1 - 7e-07 28.5 0.0 1.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EEB05845.1 - 0.05 12.7 0.0 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain SMC_N PF02463.19 EEB05847.2 - 2.4e-58 197.2 63.0 1.5e-34 119.4 0.1 5.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEB05847.2 - 2e-25 89.4 0.1 9.5e-25 87.2 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEB05847.2 - 2.8e-10 40.5 22.4 1.5e-07 31.6 0.1 4.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB05847.2 - 1.8e-05 24.4 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EEB05847.2 - 0.0014 18.4 38.8 0.0014 18.4 38.8 4.9 2 2 0 2 2 2 1 AAA ATPase domain SYCE1 PF15233.6 EEB05847.2 - 0.0064 16.6 21.3 0.0064 16.6 21.3 6.4 4 3 0 5 5 5 1 Synaptonemal complex central element protein 1 ABC_tran PF00005.27 EEB05847.2 - 0.28 11.7 0.0 0.28 11.7 0.0 7.1 3 2 0 5 5 5 0 ABC transporter TAF8_C PF10406.9 EEB05848.2 - 1.6e-19 70.2 2.1 3.3e-19 69.2 2.1 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Ino80_Iec3 PF14612.6 EEB05849.1 - 5.4e-11 43.6 0.2 7.3e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sld5 PF05916.11 EEB05850.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Amidoligase_2 PF12224.8 EEB05850.1 - 0.043 13.5 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme Pkinase PF00069.25 EEB05851.1 - 1.4e-23 83.6 0.0 3.3e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05851.1 - 9.5e-16 57.9 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2401 PF10287.9 EEB05852.1 - 5.1e-89 297.8 3.2 5.1e-89 297.8 3.2 2.1 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EEB05852.1 - 4e-29 100.8 0.1 1e-28 99.5 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Apt1 PF10351.9 EEB05852.1 - 9.9 4.9 8.1 13 4.5 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sulfate_transp PF00916.20 EEB05853.2 - 1.6e-72 244.4 18.8 2.3e-72 243.8 18.8 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EEB05853.2 - 1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EEB05853.2 - 2.3e-09 36.9 0.3 4.6e-09 35.9 0.3 1.5 1 0 0 1 1 1 1 STAS domain ThiF PF00899.21 EEB05854.1 - 3e-61 206.9 0.0 4.2e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EEB05854.1 - 3.6e-15 55.9 0.0 6.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.9 EEB05854.1 - 0.036 14.0 0.1 1.5 8.6 0.0 2.2 1 1 0 2 2 2 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 EEB05854.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 EEB05855.1 - 1.1e-14 54.6 13.7 0.12 13.3 0.1 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05855.1 - 1.1e-09 38.5 0.1 0.0097 16.2 0.0 5.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Kelch_3 PF13415.6 EEB05855.1 - 0.055 13.8 0.1 14 6.1 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Phosphoesterase PF04185.14 EEB05855.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoesterase family Syja_N PF02383.18 EEB05856.1 - 1.4e-81 274.3 0.0 2e-81 273.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain AA_kinase PF00696.28 EEB05857.1 - 7.5e-43 146.9 0.1 1.1e-42 146.3 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EEB05857.1 - 1.9e-11 43.5 0.1 1.8e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EEB05857.1 - 3.9e-11 42.6 3.2 1.3e-08 34.5 0.2 3.4 3 0 0 3 3 3 2 ACT domain Pescadillo_N PF06732.11 EEB05858.1 - 1e-127 425.4 1.1 1e-127 425.4 1.1 2.2 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EEB05858.1 - 4.6e-11 43.0 0.0 1.3e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EEB05858.1 - 0.12 12.8 0.7 0.52 10.7 0.0 2.5 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain DUF3293 PF11697.8 EEB05858.1 - 1.6 9.2 5.7 0.3 11.6 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Cytokin_check_N PF10407.9 EEB05859.1 - 2e-15 56.5 0.1 4.3e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus MCM PF00493.23 EEB05860.1 - 1.1e-106 355.0 0.0 1.8e-106 354.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEB05860.1 - 1.6e-31 108.8 0.1 3.7e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEB05860.1 - 8.1e-21 74.2 1.1 2.2e-20 72.9 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEB05860.1 - 1.4e-17 64.1 0.3 3.5e-17 62.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEB05860.1 - 9.4e-08 31.7 0.0 9e-06 25.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEB05860.1 - 7.4e-07 29.2 0.0 2.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEB05860.1 - 0.0074 16.2 0.1 0.033 14.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EEB05860.1 - 0.018 14.8 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 EEB05860.1 - 0.086 12.5 0.1 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EEB05860.1 - 0.39 11.4 1.5 1.2 9.9 0.8 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Ribonuc_red_sm PF00268.21 EEB05861.1 - 1.9e-114 381.9 1.4 2.3e-114 381.6 1.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TRM PF02005.16 EEB05862.1 - 1.2e-146 488.8 0.0 1.5e-146 488.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EEB05862.1 - 7.3e-05 22.6 0.4 0.00013 21.8 0.4 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DEAD PF00270.29 EEB05863.1 - 2.7e-11 43.5 0.0 7.3e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEB05863.1 - 0.034 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EEB05863.1 - 0.044 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 EEB05864.1 - 8.7e-14 51.1 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB05864.1 - 0.0047 16.5 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB05864.1 - 0.04 13.9 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif S4 PF01479.25 EEB05865.1 - 3.4e-10 39.5 0.1 6.7e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EEB05865.1 - 5.9e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain NTP_transferase PF00483.23 EEB05866.2 - 1e-27 97.3 0.0 1.4e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EEB05866.2 - 5.9e-11 41.6 6.7 1.5e-07 30.8 0.6 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEB05866.2 - 1.7e-06 28.5 0.0 4.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EEB05866.2 - 9.7e-05 21.5 1.9 0.0011 18.0 1.8 2.2 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EEB05866.2 - 0.13 10.4 0.5 0.68 8.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Pex14_N PF04695.13 EEB05867.1 - 8.7e-18 65.5 4.4 2.4e-13 51.1 0.6 3.5 2 2 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1759 PF03564.15 EEB05867.1 - 0.071 13.0 2.1 0.56 10.1 1.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Calpain_inhib PF00748.19 EEB05867.1 - 0.083 13.4 0.1 0.083 13.4 0.1 2.2 2 0 0 2 2 2 0 Calpain inhibitor Hemagglutinin PF00509.18 EEB05867.1 - 0.4 9.0 1.3 0.52 8.6 1.3 1.1 1 0 0 1 1 1 0 Haemagglutinin FUSC PF04632.12 EEB05867.1 - 1.1 7.8 3.6 2.5 6.5 3.6 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Senescence_reg PF04520.13 EEB05867.1 - 2.3 9.0 6.9 3.4 8.5 6.9 1.4 1 1 0 1 1 1 0 Senescence regulator KxDL PF10241.9 EEB05867.1 - 2.5 8.4 8.6 0.98 9.7 0.4 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein Snapin_Pallidin PF14712.6 EEB05867.1 - 5.3 7.5 17.3 4 7.9 4.8 2.8 2 1 1 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.10 EEB05867.1 - 5.7 7.1 12.7 0.14 12.4 2.9 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family 2OG-FeII_Oxy_2 PF13532.6 EEB05868.1 - 2.5e-38 132.2 0.0 4.7e-38 131.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF617 PF04759.13 EEB05868.1 - 0.19 11.8 0.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF617 DUF747 PF05346.11 EEB05869.1 - 1.1e-104 350.3 14.4 1.8e-104 349.7 14.4 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family Complex1_LYR PF05347.15 EEB05870.1 - 1.6e-16 60.1 1.3 2.6e-16 59.4 1.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEB05870.1 - 2.8e-05 24.8 0.6 3e-05 24.7 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EEB05870.1 - 0.0022 18.6 0.1 0.0029 18.2 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DHHC PF01529.20 EEB05871.1 - 2.5e-32 111.8 11.5 2.5e-32 111.8 11.5 2.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase SPRY PF00622.28 EEB05872.1 - 1.6e-08 34.6 0.2 4.2e-07 30.1 0.0 3.0 3 0 0 3 3 3 1 SPRY domain PHD PF00628.29 EEB05872.1 - 0.0018 18.1 10.6 0.0036 17.2 10.6 1.5 1 0 0 1 1 1 1 PHD-finger TCR PF03638.15 EEB05872.1 - 1.1 9.7 7.2 2.5 8.5 7.2 1.6 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Bystin PF05291.11 EEB05873.1 - 1.6e-132 441.2 0.0 2.1e-132 440.8 0.0 1.1 1 0 0 1 1 1 1 Bystin RanGAP1_C PF07834.11 EEB05873.1 - 0.00011 21.9 2.1 0.00023 20.9 2.1 1.4 1 0 0 1 1 1 1 RanGAP1 C-terminal domain Sec63 PF02889.16 EEB05874.1 - 1.7e-127 423.9 4.3 3.5e-75 252.5 0.6 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEB05874.1 - 5.4e-54 182.6 0.3 1.6e-27 96.4 0.2 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EEB05874.1 - 2.3e-24 86.3 0.0 3e-12 46.9 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB05874.1 - 1.6e-17 63.8 0.1 2.6e-06 27.8 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEB05874.1 - 5.9e-08 32.7 0.0 0.0025 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEB05874.1 - 1.3e-06 28.8 2.1 0.05 13.9 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEB05874.1 - 3.4e-06 27.5 0.5 0.0081 16.5 0.4 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EEB05874.1 - 0.0061 17.0 1.1 0.77 10.2 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 EEB05874.1 - 0.012 15.8 0.0 0.055 13.7 0.0 2.1 1 0 0 1 1 1 0 N-terminal helicase PWI domain PhoH PF02562.16 EEB05874.1 - 0.013 14.9 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EEB05874.1 - 0.12 12.2 0.3 5.2 6.8 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EEB05874.1 - 0.13 11.6 0.0 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Longin PF13774.6 EEB05875.1 - 7.7e-16 57.9 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EEB05875.1 - 1.3e-14 53.7 0.8 2e-14 53.1 0.8 1.2 1 0 0 1 1 1 1 Synaptobrevin TetR_C_29 PF17938.1 EEB05875.1 - 0.034 14.2 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UPF0449 PF15136.6 EEB05875.1 - 0.086 13.3 0.1 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GAT PF03127.14 EEB05875.1 - 0.12 12.7 0.3 0.28 11.5 0.3 1.6 1 1 0 1 1 1 0 GAT domain Snf7 PF03357.21 EEB05876.2 - 9.2e-14 51.4 15.3 1.3e-13 50.9 15.3 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EEB05876.2 - 0.0048 16.8 5.9 0.0073 16.2 5.9 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Arc PF03869.14 EEB05876.2 - 0.015 15.1 0.9 0.14 12.0 1.1 2.3 2 0 0 2 2 2 0 Arc-like DNA binding domain DUF4061 PF13270.6 EEB05876.2 - 8.2 6.8 8.8 0.5 10.7 0.7 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) Tfb2 PF03849.14 EEB05877.1 - 8.9e-141 469.0 0.1 1.2e-140 468.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EEB05877.1 - 4e-24 84.8 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EEB05877.1 - 7.3e-05 22.9 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 EEB05878.1 - 1.8e-12 47.4 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EEB05878.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ChaC PF04752.12 EEB05879.1 - 2.2e-59 200.5 0.0 2.7e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Med17 PF10156.9 EEB05880.1 - 1.1e-96 324.3 0.4 1.4e-96 324.0 0.4 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Arf PF00025.21 EEB05882.1 - 5.8e-67 224.5 0.0 6.5e-67 224.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EEB05882.1 - 2e-11 43.6 0.0 2.4e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EEB05882.1 - 5e-09 35.8 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EEB05882.1 - 1.3e-06 28.6 0.0 3.7e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EEB05882.1 - 3.7e-06 27.0 0.0 7e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EEB05882.1 - 2.7e-05 23.8 0.0 3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EEB05882.1 - 0.00052 19.4 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEB05882.1 - 0.093 12.3 0.0 5.6 6.4 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EEB05882.1 - 0.1 12.3 0.0 0.41 10.4 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EEB05882.1 - 0.17 11.4 0.0 9.8 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VHS PF00790.19 EEB05883.1 - 5e-27 94.5 0.0 2.2e-26 92.4 0.0 2.0 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 EEB05883.1 - 4.4e-09 36.5 0.4 1.2e-08 35.2 0.4 1.8 1 0 0 1 1 1 1 GAT domain DAP3 PF10236.9 EEB05883.1 - 0.075 12.2 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PBP1_TM PF14812.6 EEB05883.1 - 3.1 8.2 6.8 10 6.6 6.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_10 PF16588.5 EEB05884.1 - 1.4 8.7 7.7 2.8 7.8 7.7 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Med10 PF09748.9 EEB05885.1 - 3.3e-29 101.3 0.0 3.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex IBD PF10416.9 EEB05885.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD zf-MYND PF01753.18 EEB05886.1 - 7.2e-07 29.2 21.7 1.5e-06 28.1 21.7 1.6 1 1 0 1 1 1 1 MYND finger Arm PF00514.23 EEB05886.1 - 0.047 13.8 0.9 0.36 10.9 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HAT PF02184.16 EEB05887.2 - 8.5e-21 73.6 59.8 6e-14 51.7 1.8 13.3 12 2 0 12 12 12 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EEB05887.2 - 4.1e-20 70.8 31.4 0.019 15.7 0.7 11.2 6 3 6 12 12 11 7 Tetratricopeptide repeat Suf PF05843.14 EEB05887.2 - 1.3e-16 61.5 24.4 0.0018 18.3 0.8 6.7 5 2 1 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EEB05887.2 - 2.4e-10 40.7 0.2 0.027 15.0 0.0 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEB05887.2 - 1.6e-08 34.0 12.8 0.16 12.1 0.0 9.2 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEB05887.2 - 1.2e-07 31.3 9.8 1.2 8.3 0.0 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05887.2 - 3.3e-06 26.9 1.3 4.6 7.7 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05887.2 - 1.5e-05 25.5 15.3 0.19 12.4 0.5 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB05887.2 - 5.5e-05 23.5 16.9 34 5.4 0.0 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEB05887.2 - 0.00046 20.3 4.8 0.47 10.6 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEB05887.2 - 0.00077 19.7 4.3 0.024 15.0 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB05887.2 - 0.029 14.6 12.8 3.4 8.0 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB05887.2 - 0.084 13.1 1.4 23 5.3 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1241 PF06840.11 EEB05887.2 - 0.12 12.0 0.8 1.2 8.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1241) NRDE-2 PF08424.10 EEB05887.2 - 0.22 10.6 22.8 0.27 10.3 0.1 5.7 4 3 3 7 7 7 0 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 EEB05887.2 - 0.63 10.1 15.8 0.069 13.2 0.6 5.8 6 1 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 DUF3987 PF13148.6 EEB05887.2 - 0.97 8.4 6.6 0.063 12.3 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Pre-PUA PF17832.1 EEB05888.2 - 2.7e-26 92.1 0.1 4e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EEB05888.2 - 1.7e-17 63.1 0.2 2.5e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EEB05888.2 - 0.05 13.9 0.3 0.12 12.7 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) Hira PF07569.11 EEB05889.1 - 3.4e-69 233.0 0.2 6.8e-69 232.0 0.2 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EEB05889.1 - 1.1e-30 105.2 28.2 1.3e-07 32.2 0.3 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB05889.1 - 2e-10 40.8 0.5 0.14 12.5 0.1 6.5 5 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EEB05889.1 - 1.8e-09 37.2 4.2 5.1e-09 35.8 4.2 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EEB05889.1 - 6.8e-05 22.7 0.2 0.03 14.3 0.2 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EEB05889.1 - 0.029 12.4 0.2 0.89 7.5 0.1 2.1 1 1 1 2 2 2 0 IKI3 family PDE6_gamma PF04868.12 EEB05889.1 - 0.93 9.8 2.7 2 8.7 2.7 1.5 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit TPR_2 PF07719.17 EEB05890.1 - 0.0014 18.6 0.3 4.3 7.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat PWI PF01480.17 EEB05890.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 PWI domain ATP-synt_Eps PF04627.13 EEB05891.1 - 1.7e-18 66.3 0.6 2.2e-18 65.9 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ChAPs PF09295.10 EEB05892.1 - 2.5e-154 514.1 0.0 6e-153 509.5 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 EEB05892.1 - 6.4e-07 29.0 1.2 4.5 7.6 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB05892.1 - 6.3e-06 26.6 0.1 15 6.7 0.0 6.2 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEB05892.1 - 9.7e-06 26.0 0.0 0.18 12.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB05892.1 - 4.3e-05 23.7 1.2 0.041 14.1 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EEB05892.1 - 0.0092 15.8 0.5 7.5 6.6 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB05892.1 - 0.016 15.4 0.1 36 4.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEB05892.1 - 0.04 14.6 0.1 19 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0300 PF08594.10 EEB05893.2 - 0.00048 19.5 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) DASH_Ask1 PF08655.10 EEB05894.1 - 0.0029 17.5 0.4 0.0094 15.8 0.3 1.9 2 0 0 2 2 2 1 DASH complex subunit Ask1 PGA2 PF07543.12 EEB05895.1 - 1e-35 122.7 0.3 1.2e-35 122.5 0.3 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF2183 PF09949.9 EEB05896.1 - 7.7e-23 80.7 0.0 1.7e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Ribosomal_L26 PF16906.5 EEB05897.1 - 2.1e-37 127.4 3.3 2.6e-37 127.1 3.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EEB05897.1 - 1.6e-06 27.9 0.3 1.6e-06 27.9 0.3 2.0 3 0 0 3 3 3 1 KOW motif DUF4663 PF15668.5 EEB05897.1 - 0.013 14.6 0.5 0.014 14.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DUF1223 PF06764.11 EEB05897.1 - 0.033 14.2 0.2 0.036 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) OPT PF03169.15 EEB05898.2 - 4.1e-203 676.4 39.2 4.7e-203 676.2 39.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3169 PF11368.8 EEB05898.2 - 0.015 14.8 0.0 0.049 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) cobW PF02492.19 EEB05899.1 - 1.7e-47 161.3 0.7 2.6e-47 160.7 0.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEB05899.1 - 2.1e-05 24.4 0.0 7.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EEB05899.1 - 0.0075 16.2 0.2 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EEB05899.1 - 0.028 13.9 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phage_tail_APC PF16778.5 EEB05899.1 - 0.043 13.7 0.2 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein AAA_16 PF13191.6 EEB05899.1 - 0.094 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EEB05899.1 - 0.11 11.8 0.1 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Cactin_mid PF10312.9 EEB05899.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin PriC PF07445.12 EEB05899.1 - 0.55 10.1 2.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Primosomal replication protein priC Glycos_transf_4 PF00953.21 EEB05900.1 - 3.1e-34 118.2 12.1 3.1e-34 118.2 12.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 Baculo_11_kDa PF06143.11 EEB05900.1 - 0.14 11.8 0.7 0.33 10.6 0.7 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Hira PF07569.11 EEB05901.1 - 1.5e-70 237.4 0.1 2.6e-70 236.6 0.1 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EEB05901.1 - 9.5e-12 45.3 5.2 2.7e-05 24.8 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 EEB05901.1 - 0.05 13.6 0.1 8.2 6.5 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS1 PF14779.6 EEB05901.1 - 0.16 11.4 0.0 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Zn_clus PF00172.18 EEB05902.2 - 1.6e-08 34.5 10.8 2.5e-08 33.9 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC117 PF15810.5 EEB05904.1 - 0.082 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Kinesin PF00225.23 EEB05905.1 - 1.2e-69 234.9 0.5 2.3e-69 233.9 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEB05905.1 - 8.9e-12 45.2 0.0 1.4e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding PKcGMP_CC PF16808.5 EEB05905.1 - 0.0027 17.5 8.0 0.04 13.8 1.3 3.4 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase GTSE1_N PF15259.6 EEB05905.1 - 0.31 11.2 9.3 12 6.1 5.1 2.8 2 1 1 3 3 3 0 G-2 and S-phase expressed 1 DUF4665 PF15679.5 EEB05905.1 - 2.2 8.9 5.3 3 8.5 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) TMPIT PF07851.13 EEB05905.1 - 2.4 7.4 7.0 4.3 6.5 7.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.6 EEB05905.1 - 2.4 8.9 12.0 1.1 9.9 5.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Gal4_dimer PF03902.13 EEB05905.1 - 2.7 8.2 7.4 2.8 8.2 5.1 2.2 2 1 0 2 2 2 0 Gal4-like dimerisation domain Exonuc_VII_L PF02601.15 EEB05905.1 - 3.2 7.3 8.3 6.5 6.2 8.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit PHM7_cyt PF14703.6 EEB05905.1 - 3.4 7.9 8.3 29 4.9 8.3 2.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cep57_MT_bd PF06657.13 EEB05905.1 - 5.5 7.5 12.7 0.81 10.2 5.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 EEB05905.1 - 5.8 7.6 15.9 0.74 10.5 9.1 2.7 2 0 0 2 2 2 0 SlyX AAA_30 PF13604.6 EEB05905.1 - 6.7 6.4 8.5 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain UQ_con PF00179.26 EEB05906.2 - 2.4e-43 147.2 0.0 2.9e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EEB05906.2 - 1.3e-09 37.7 0.1 2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 EEB05906.2 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UBA_6 PF18039.1 EEB05906.2 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Prok-E2_B PF14461.6 EEB05906.2 - 0.064 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RXLR PF16810.5 EEB05907.1 - 0.051 14.0 1.2 0.08 13.4 1.2 1.4 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity ABC1 PF03109.16 EEB05908.1 - 5.2e-35 120.2 0.0 1.1e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family FOXP-CC PF16159.5 EEB05909.1 - 0.0053 17.3 9.7 0.34 11.6 4.4 2.9 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EEB05909.1 - 0.11 13.4 6.9 0.21 12.5 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EEB05909.1 - 2 9.0 6.5 0.27 11.8 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type CENP-S PF15630.6 EEB05910.1 - 1.8e-27 95.5 0.2 2.6e-27 95.0 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEB05910.1 - 2.8e-07 30.6 0.1 3.3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EEB05910.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EEB05910.1 - 0.0071 16.6 0.6 0.096 13.0 0.0 2.6 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EEB05910.1 - 0.12 12.4 1.0 0.23 11.5 0.4 1.6 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 EEB05910.1 - 0.27 11.4 1.8 2.1 8.6 0.1 2.7 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Pept_tRNA_hydro PF01195.19 EEB05911.2 - 2.7e-41 141.4 0.0 3.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Calpain_III PF01067.22 EEB05911.2 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Calpain large subunit, domain III Pyridoxal_deC PF00282.19 EEB05912.1 - 9e-64 215.5 0.0 1.1e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EEB05912.1 - 2.3e-06 26.9 0.0 3.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EEB05912.1 - 0.039 12.7 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Myosin_head PF00063.21 EEB05913.2 - 1.1e-251 836.8 9.7 1.6e-251 836.4 9.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EEB05913.2 - 1.9e-18 66.6 1.7 1.9e-18 66.6 1.7 4.6 6 0 0 6 6 6 1 DIL domain IQ PF00612.27 EEB05913.2 - 5.8e-14 50.5 15.8 0.0025 17.5 0.4 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_16 PF13191.6 EEB05913.2 - 0.00084 19.8 0.3 0.59 10.5 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEB05913.2 - 0.015 15.6 0.0 0.087 13.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEB05913.2 - 0.086 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Fucose_iso_C PF02952.17 EEB05913.2 - 0.3 10.8 1.1 1.2 8.8 0.0 2.6 4 0 0 4 4 4 0 L-fucose isomerase, C-terminal domain ABC_tran PF00005.27 EEB05913.2 - 0.48 10.9 3.1 1 9.9 0.0 3.0 4 0 0 4 4 4 0 ABC transporter EST1_DNA_bind PF10373.9 EEB05914.2 - 3.6e-25 89.0 10.5 3.6e-25 89.0 10.5 2.1 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EEB05914.2 - 1.3e-18 68.0 2.3 1.3e-18 68.0 2.3 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 Asp_Glu_race PF01177.22 EEB05914.2 - 0.03 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase GIT_CC PF16559.5 EEB05914.2 - 0.13 12.2 5.4 1.8 8.5 0.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF842 PF05811.13 EEB05914.2 - 10 5.9 7.0 28 4.4 1.4 3.6 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Ribosomal_L22 PF00237.19 EEB05915.1 - 1.1e-38 131.6 0.1 1.6e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e UBA PF00627.31 EEB05916.1 - 7.5e-28 96.0 7.0 5.3e-14 51.8 0.6 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EEB05916.1 - 3.6e-25 87.5 11.6 6.3e-25 86.7 11.6 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EEB05916.1 - 1.3e-24 85.7 1.4 2.4e-24 84.9 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEB05916.1 - 1.3e-08 34.6 2.8 2.3e-08 33.7 2.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EEB05916.1 - 5.4e-06 26.5 0.9 1.2e-05 25.3 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEB05916.1 - 1.4e-05 25.6 0.5 3.3e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB05916.1 - 0.0015 18.9 0.2 0.0034 17.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain MCM_N PF14551.6 EEB05916.1 - 0.002 18.7 0.1 0.049 14.2 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain DUF3135 PF11333.8 EEB05916.1 - 0.018 15.3 0.4 0.16 12.2 0.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) UBA_3 PF09288.10 EEB05916.1 - 0.042 13.7 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF1421 PF07223.11 EEB05916.1 - 0.084 12.7 0.0 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain (DUF1421) MGC-24 PF05283.11 EEB05916.1 - 0.39 11.2 8.1 0.18 12.2 1.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pex14_N PF04695.13 EEB05916.1 - 3 8.5 12.4 4.9 7.8 2.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 EEB05916.1 - 4.5 7.7 11.8 7.9 6.9 2.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex NAP PF00956.18 EEB05917.1 - 3.9e-78 262.4 2.7 7e-78 261.5 2.7 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) SecA_SW PF07516.13 EEB05917.1 - 0.019 15.0 0.1 0.03 14.4 0.1 1.6 1 1 0 1 1 1 0 SecA Wing and Scaffold domain Methyltransf_34 PF11312.8 EEB05917.1 - 0.054 12.7 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Focal_AT PF03623.13 EEB05917.1 - 0.11 12.5 1.2 0.2 11.6 1.2 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region CS PF04969.16 EEB05917.1 - 0.16 13.0 1.1 25 6.0 0.0 2.5 2 0 0 2 2 2 0 CS domain Fibrillarin PF01269.17 EEB05918.1 - 1.4e-103 344.9 0.1 1.7e-103 344.6 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EEB05918.1 - 5.8e-07 29.4 0.0 8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EEB05918.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EEB05918.1 - 0.026 14.2 0.0 0.084 12.5 0.0 1.7 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 EEB05918.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 EEB05918.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Secretin_N PF03958.17 EEB05918.1 - 0.32 11.4 2.2 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain ECH_2 PF16113.5 EEB05919.1 - 9.9e-105 350.7 0.0 1.1e-104 350.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EEB05919.1 - 7.4e-27 94.2 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UTP25 PF06862.12 EEB05920.1 - 6.7e-196 651.7 10.4 8.2e-196 651.4 10.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EEB05920.1 - 2.6e-05 24.1 0.1 0.00071 19.4 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Glyco_hydro_59 PF02057.15 EEB05920.1 - 0.033 13.4 0.0 0.087 12.0 0.0 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 59 GreA_GreB_N PF03449.15 EEB05920.1 - 0.64 10.2 5.6 1.4 9.1 5.6 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal CTP_transf_like PF01467.26 EEB05921.1 - 2.3e-33 115.4 0.0 4.4e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like AMP-binding PF00501.28 EEB05922.1 - 1.5e-86 290.7 0.0 1.9e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEB05922.1 - 1e-16 61.6 1.2 3.3e-16 60.0 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EEB05922.1 - 0.0002 20.3 0.0 0.013 14.4 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter RTX_C PF08339.10 EEB05922.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain bVLRF1 PF18826.1 EEB05923.1 - 3e-58 195.9 0.4 3e-58 195.9 0.4 2.6 3 1 1 4 4 4 1 bacteroidetes VLRF1 release factor Ank PF00023.30 EEB05923.1 - 0.033 14.7 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ribosomal_L22 PF00237.19 EEB05923.1 - 0.14 12.4 2.2 0.27 11.5 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e DUF2254 PF10011.9 EEB05923.1 - 1.4 7.7 6.4 0.37 9.6 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) RRM_1 PF00076.22 EEB05924.1 - 1.2e-13 50.6 0.0 2.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB05924.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rotamase_3 PF13616.6 EEB05925.1 - 3.8e-19 69.4 0.2 7e-19 68.5 0.2 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EEB05925.1 - 5.5e-17 62.5 0.0 6.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EEB05925.1 - 7.7e-05 23.5 0.0 9.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain PhoLip_ATPase_C PF16212.5 EEB05926.2 - 1.6e-47 162.4 18.9 2.1e-47 162.0 18.9 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 EEB05926.2 - 1e-09 38.4 0.0 1.6e-08 34.5 0.0 2.7 2 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEB05926.2 - 6.3e-09 36.4 1.1 4.8e-05 23.7 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEB05926.2 - 0.00031 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_Coat_B PF05356.11 EEB05926.2 - 0.083 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Phage Coat protein B Mcp5_PH PF12814.7 EEB05927.1 - 1.7e-06 28.1 0.4 2.6e-05 24.3 0.4 2.8 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.6 EEB05927.1 - 0.032 14.5 0.2 0.098 13.0 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 EEB05927.1 - 0.068 13.7 3.4 0.21 12.1 0.1 3.2 3 0 0 3 3 3 0 PH domain Ank_4 PF13637.6 EEB05928.1 - 1.3e-38 130.8 6.7 1.2e-09 38.5 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB05928.1 - 7.2e-35 119.4 4.7 3.4e-10 40.4 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB05928.1 - 1e-29 102.2 0.1 1.2e-09 38.2 0.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EEB05928.1 - 3.1e-24 84.3 0.6 0.0013 19.1 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EEB05928.1 - 2.1e-22 76.8 2.7 0.00044 20.5 0.0 6.1 7 0 0 7 7 7 5 Ankyrin repeat DUF2000 PF09391.10 EEB05928.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Glyoxalase_6 PF18029.1 EEB05928.1 - 0.16 12.8 0.3 0.33 11.8 0.3 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain Ribonuc_P_40 PF08584.11 EEB05929.1 - 7e-52 176.5 0.0 9.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_lig_T4_1 PF09511.10 EEB05930.1 - 3.6e-79 265.7 0.0 6.6e-79 264.8 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 EEB05930.1 - 2.6e-46 158.1 0.4 5.8e-46 157.0 0.4 1.5 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EEB05930.1 - 1.6e-43 148.7 0.0 5.3e-43 147.0 0.0 1.9 2 0 0 2 2 2 1 tRNA ligase kinase domain RNA_ligase PF09414.10 EEB05930.1 - 0.0068 16.7 0.1 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 RNA ligase CABIT PF12736.7 EEB05930.1 - 0.1 11.9 0.0 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, PK_C PF02887.16 EEB05930.1 - 0.11 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain IU_nuc_hydro PF01156.19 EEB05931.2 - 2.1e-86 290.3 0.2 2.6e-86 290.0 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CheY-binding PF09078.11 EEB05931.2 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 CheY binding CBFD_NFYB_HMF PF00808.23 EEB05932.1 - 2.8e-14 53.1 1.0 5.4e-14 52.2 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB05932.1 - 0.00044 20.6 0.5 0.00044 20.6 0.5 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SecE PF00584.20 EEB05933.1 - 4.9e-14 52.0 0.1 5.5e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Hol_Tox PF16935.5 EEB05933.1 - 0.0088 16.1 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Putative Holin-like Toxin (Hol-Tox) Con-6 PF10346.9 EEB05934.1 - 1e-30 105.4 1.7 2.4e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Fip1 PF05182.13 EEB05935.1 - 1.3e-24 85.4 1.8 2.3e-24 84.6 1.8 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 EEB05936.2 - 1.9e-14 54.2 76.9 3e-09 37.6 33.7 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region CCAP PF11105.8 EEB05936.2 - 0.024 14.6 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a Baculo_PEP_C PF04513.12 EEB05936.2 - 0.61 10.1 7.3 0.24 11.4 2.5 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.6 EEB05936.2 - 1.6 9.4 5.2 2.4 8.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TFIIA PF03153.13 EEB05936.2 - 3 7.8 21.4 4.2 7.2 21.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF948 PF06103.11 EEB05936.2 - 4.9 7.5 8.4 0.93 9.8 1.3 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 EEB05936.2 - 7.9 7.0 6.5 11 6.5 0.2 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 EEB05937.1 - 1.8e-47 161.9 0.0 2.5e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05937.1 - 4.8e-22 78.5 0.0 7.1e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05937.1 - 1.4e-06 27.8 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEB05937.1 - 0.00048 20.1 0.3 0.051 13.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEB05937.1 - 0.0031 16.9 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB05937.1 - 0.039 13.6 0.1 0.78 9.3 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EEB05937.1 - 0.078 11.7 0.8 0.24 10.1 0.8 1.9 1 1 0 1 1 1 0 Fungal protein kinase CPSase_L_D2 PF02786.17 EEB05938.1 - 1.3e-113 377.7 0.3 5.9e-84 280.8 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EEB05938.1 - 8.5e-50 167.9 0.0 1.8e-49 166.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EEB05938.1 - 3.2e-44 151.0 0.0 6.6e-44 150.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EEB05938.1 - 9.5e-43 145.8 0.0 2.2e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EEB05938.1 - 1e-38 132.4 0.0 2.2e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EEB05938.1 - 6.2e-32 110.8 0.0 2.1e-31 109.1 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 EEB05938.1 - 1.2e-18 67.4 0.9 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EEB05938.1 - 2e-16 59.9 0.0 2e-15 56.7 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EEB05938.1 - 3.6e-15 56.0 0.1 3.5e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EEB05938.1 - 1.1e-08 34.9 0.0 0.00047 19.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 EEB05938.1 - 8.5e-06 25.7 0.1 0.0064 16.3 0.0 4.5 5 0 0 5 5 5 1 DJ-1/PfpI family RimK PF08443.11 EEB05938.1 - 5.4e-05 22.9 0.1 0.24 11.0 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EEB05938.1 - 0.00012 22.2 0.3 0.77 9.8 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EEB05938.1 - 0.00022 21.0 0.1 0.046 13.5 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 EEB05938.1 - 0.011 15.5 2.1 2.6 7.8 0.0 3.5 5 0 0 5 5 5 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Kri1_C PF12936.7 EEB05939.1 - 1.2e-29 102.3 0.5 1.2e-29 102.3 0.5 3.7 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 EEB05939.1 - 2.7e-24 85.7 16.4 2.7e-24 85.7 16.4 5.6 4 2 1 5 5 5 1 KRI1-like family UCH_1 PF13423.6 EEB05940.2 - 5.5e-73 246.4 2.1 7.7e-73 245.9 2.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EEB05940.2 - 1.8e-26 93.6 0.0 3.6e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 EEB05940.2 - 0.13 13.2 0.1 1.6 9.7 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat IBN_N PF03810.19 EEB05942.2 - 8.2e-08 32.1 0.4 3.4e-07 30.1 0.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 EEB05942.2 - 0.0026 17.4 0.1 0.0069 16.1 0.1 1.8 1 0 0 1 1 1 1 Importin 13 repeat DUF3689 PF12463.8 EEB05942.2 - 0.0079 15.5 0.1 0.025 13.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Importin_rep_3 PF18806.1 EEB05942.2 - 0.13 12.3 0.0 2 8.5 0.0 2.7 2 1 0 2 2 2 0 Importin 13 repeat Creatinase_N_2 PF16189.5 EEB05943.1 - 5.8e-47 159.8 0.1 5e-46 156.7 0.1 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EEB05943.1 - 3.8e-42 144.3 0.0 6e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EEB05943.1 - 2.2e-21 75.6 0.2 2.2e-21 75.6 0.2 2.2 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EEB05943.1 - 2.5e-18 67.0 0.0 7.2e-14 52.6 0.0 2.6 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Ysc84 PF04366.12 EEB05944.1 - 4.9e-43 145.9 0.3 7.5e-43 145.3 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EEB05944.1 - 1.4e-13 50.2 0.0 2.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB05944.1 - 4.1e-11 42.6 0.0 7.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB05944.1 - 1.1e-10 41.0 0.0 2.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RAP1 PF07218.11 EEB05944.1 - 1.2 7.3 3.8 1.6 7.0 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vps5 PF09325.10 EEB05945.2 - 1.8e-08 34.3 4.2 2.7e-08 33.6 4.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EEB05945.2 - 5.6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF948 PF06103.11 EEB05945.2 - 0.0014 18.9 0.5 0.098 12.9 1.5 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Flavodoxin_1 PF00258.25 EEB05946.2 - 6.3e-35 120.5 0.0 1.5e-34 119.3 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EEB05946.2 - 1.4e-29 103.3 0.0 2.1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEB05946.2 - 3.8e-17 62.9 0.0 7.3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EEB05946.2 - 0.02 14.6 0.0 1.3 8.7 0.0 2.7 4 0 0 4 4 4 0 Flavodoxin domain Hormone_3 PF00159.18 EEB05946.2 - 0.069 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Cyclin_N PF00134.23 EEB05947.1 - 3.5e-10 39.7 8.1 1.2e-08 34.7 3.8 2.8 2 1 0 2 2 2 2 Cyclin, N-terminal domain Pex24p PF06398.11 EEB05948.1 - 0.00016 20.8 3.6 0.00016 20.8 3.6 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin zf-RING_9 PF13901.6 EEB05948.1 - 0.056 13.4 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Peptidase_S10 PF00450.22 EEB05949.2 - 2.4e-61 208.4 0.3 3.6e-61 207.8 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase COX5B PF01215.19 EEB05950.2 - 1.2e-46 157.6 0.0 1.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EEB05950.2 - 2.4e-05 24.3 0.3 4.2e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain PGM_PMM_IV PF00408.20 EEB05951.1 - 8e-13 48.4 0.3 1.5e-12 47.5 0.3 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 EEB05951.1 - 2.6e-12 46.6 0.1 4.2e-05 23.3 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EEB05951.1 - 0.0033 18.0 0.0 0.013 16.1 0.0 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEB05951.1 - 0.0073 16.5 0.1 0.067 13.4 0.0 2.5 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III bZIP_1 PF00170.21 EEB05952.2 - 4.6e-13 49.0 9.6 7.9e-13 48.3 9.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEB05952.2 - 9.7e-06 25.6 8.8 1.6e-05 24.9 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EEB05952.2 - 0.0044 17.5 3.6 0.0073 16.8 3.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor SNF2_N PF00176.23 EEB05953.2 - 3.6e-51 174.0 0.4 5.9e-51 173.2 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB05953.2 - 2.1e-15 57.1 0.0 5.4e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB05953.2 - 8.8e-13 48.6 0.0 2.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEB05953.2 - 3.7e-05 23.6 0.0 7.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CBM_1 PF00734.18 EEB05954.1 - 1.1e-40 137.2 90.9 5.4e-12 45.5 15.2 5.6 6 0 0 6 6 6 4 Fungal cellulose binding domain AMP-binding PF00501.28 EEB05955.1 - 1.8e-33 115.8 0.0 6.4e-23 81.0 0.0 4.4 3 2 0 3 3 3 3 AMP-binding enzyme Arf PF00025.21 EEB05956.1 - 3.2e-58 196.0 2.4 3.6e-58 195.9 2.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EEB05956.1 - 7e-15 55.0 0.0 8.1e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB05956.1 - 2.5e-14 53.5 0.0 4.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EEB05956.1 - 8.5e-12 44.9 4.7 2.2e-07 30.4 1.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEB05956.1 - 3e-11 43.1 0.1 3.7e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB05956.1 - 5.2e-09 36.2 0.0 8.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEB05956.1 - 1.3e-07 31.4 0.1 6.2e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEB05956.1 - 6.1e-06 25.8 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EEB05956.1 - 0.00027 20.9 0.4 0.024 14.6 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EEB05956.1 - 0.0017 18.0 0.3 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EEB05956.1 - 0.0042 17.5 0.0 0.0071 16.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EEB05956.1 - 0.0047 16.5 1.8 0.056 13.0 1.8 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EEB05956.1 - 0.0083 15.9 0.2 1.3 8.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EEB05956.1 - 0.0097 15.8 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EEB05956.1 - 0.013 15.8 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EEB05956.1 - 0.018 14.5 0.5 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein CdhD PF03599.16 EEB05956.1 - 0.019 13.7 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Dynamin_N PF00350.23 EEB05956.1 - 0.052 13.6 0.0 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EEB05956.1 - 0.079 13.0 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TsaE PF02367.17 EEB05956.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Lon_C PF05362.13 EEB05957.1 - 5.1e-67 225.4 0.0 1.2e-66 224.2 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EEB05957.1 - 8.1e-35 120.6 4.8 9.6e-34 117.1 4.8 2.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EEB05957.1 - 5.3e-24 85.1 0.0 1.6e-23 83.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB05957.1 - 1.5e-08 34.8 0.0 3.5e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EEB05957.1 - 7.9e-07 29.0 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EEB05957.1 - 4.6e-06 26.9 0.0 2.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEB05957.1 - 3.4e-05 24.2 0.0 0.00043 20.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEB05957.1 - 4.3e-05 24.1 0.4 0.0018 18.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EEB05957.1 - 9.8e-05 22.2 0.0 0.00098 18.9 0.0 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEB05957.1 - 0.00015 22.2 0.1 0.00081 19.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 EEB05957.1 - 0.001 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.6 EEB05957.1 - 0.0011 19.1 0.0 0.0055 16.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEB05957.1 - 0.0024 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EEB05957.1 - 0.0026 18.1 0.0 0.0058 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EEB05957.1 - 0.019 14.2 0.4 0.047 12.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 EEB05957.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EEB05957.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_30 PF13604.6 EEB05957.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EEB05957.1 - 0.037 13.9 0.3 1.1 9.1 0.0 2.6 1 1 1 2 2 2 0 NTPase SKI PF01202.22 EEB05957.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase RsgA_GTPase PF03193.16 EEB05957.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EEB05957.1 - 0.053 13.4 3.2 3.1 7.7 0.0 3.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EEB05957.1 - 0.063 12.8 0.5 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EEB05957.1 - 0.074 13.6 0.4 0.53 10.8 0.1 2.6 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 EEB05957.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EEB05957.1 - 0.16 11.3 0.6 9.6 5.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EEB05957.1 - 0.19 12.1 0.3 1.2 9.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain ATP-synt_G PF04718.15 EEB05958.1 - 3.1e-10 40.8 0.4 1e-08 35.9 0.4 2.3 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 EEB05959.1 - 2.1e-40 138.3 0.0 4.1e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB05959.1 - 1.2e-34 119.0 0.2 1.2e-33 115.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB05959.1 - 2.9e-09 37.2 1.7 3.8e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EEB05959.1 - 0.00069 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.6 EEB05959.1 - 0.0024 18.2 0.3 0.014 15.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEB05959.1 - 0.018 14.1 0.1 0.051 12.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EEB05959.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain RloB PF13707.6 EEB05959.1 - 0.62 10.2 5.3 2 8.6 2.6 2.2 2 0 0 2 2 2 0 RloB-like protein Rotamase_2 PF13145.6 EEB05959.1 - 0.77 10.6 6.3 27 5.6 0.0 2.7 2 0 0 2 2 2 0 PPIC-type PPIASE domain Ank_2 PF12796.7 EEB05960.1 - 1.7e-13 50.9 2.3 9.5e-08 32.5 0.0 3.0 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEB05960.1 - 1.4e-12 47.9 2.9 1.5e-07 31.8 0.2 3.4 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEB05960.1 - 1e-10 40.9 4.1 1.4e-05 25.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EEB05960.1 - 8.7e-10 38.7 4.4 4.7e-06 26.8 0.1 3.0 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EEB05960.1 - 9.2e-10 38.5 5.1 6.2e-05 23.3 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EEB05960.1 - 2.9e-05 23.9 0.1 0.00034 20.4 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain OmpH PF03938.14 EEB05960.1 - 0.036 14.4 3.3 0.087 13.2 3.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) F1F0-ATPsyn_F PF10791.9 EEB05960.1 - 0.093 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Exonuc_VII_L PF02601.15 EEB05960.1 - 0.099 12.2 2.8 0.19 11.3 2.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EEB05960.1 - 0.56 10.5 8.2 0.22 11.8 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein FeoB_Cyto PF17910.1 EEB05960.1 - 0.74 10.4 3.1 2.3 8.8 2.9 1.9 1 1 0 1 1 1 0 FeoB cytosolic helical domain GCS PF03074.16 EEB05961.1 - 1.9e-162 540.7 0.0 2.6e-162 540.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase zf-C2H2_jaz PF12171.8 EEB05962.1 - 3.6e-06 27.1 0.0 7.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEB05962.1 - 2.7e-05 24.4 0.2 4.9e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EEB05962.1 - 0.0013 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger NPA PF16469.5 EEB05962.1 - 0.023 15.3 1.0 0.035 14.7 1.0 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 SNRNP27 PF08648.12 EEB05962.1 - 0.046 13.8 0.5 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins GRDB PF07355.12 EEB05962.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Peptidase_S76 PF13611.6 EEB05962.1 - 0.74 10.2 3.1 3 8.2 0.0 2.6 3 0 0 3 3 3 0 Serine peptidase of plant viral polyprotein, P1 RGS PF00615.19 EEB05963.1 - 1.7e-16 60.6 0.7 4.3e-16 59.2 0.7 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EEB05963.1 - 4.3e-05 23.5 0.7 0.022 14.8 0.1 3.6 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Casc1 PF12366.8 EEB05963.1 - 0.055 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Hamartin PF04388.12 EEB05964.1 - 6.5e-10 38.3 0.0 9.3e-06 24.6 0.1 4.8 4 1 1 5 5 5 3 Hamartin protein ERM PF00769.19 EEB05964.1 - 0.019 14.8 34.9 0.08 12.7 19.4 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3301 PF11743.8 EEB05964.1 - 0.14 11.8 0.8 0.37 10.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) THOC2_N PF16134.5 EEB05965.2 - 7.4e-124 414.7 0.8 1.3e-123 413.9 0.8 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EEB05965.2 - 3e-92 309.0 0.2 4.8e-92 308.4 0.2 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EEB05965.2 - 4.1e-14 52.4 0.1 1.6e-13 50.5 0.1 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Pkinase PF00069.25 EEB05966.1 - 1.5e-60 204.8 0.0 1.8e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05966.1 - 1.2e-37 129.6 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB05966.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEB05966.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF234 PF03008.14 EEB05967.2 - 0.012 16.0 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function DEAD_2 PF06733.15 EEB05968.1 - 1.9e-58 197.0 0.0 3.6e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EEB05968.1 - 2.2e-44 151.4 1.1 1.4e-40 139.0 0.3 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EEB05968.1 - 4.4e-42 144.2 0.0 8.9e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EEB05968.1 - 7.5e-05 22.8 0.0 0.016 15.2 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 EEB05969.1 - 8.6e-48 163.0 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05969.1 - 3.8e-19 69.0 0.0 7.7e-19 68.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EEB05969.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_4 PF13691.6 EEB05970.1 - 3.3e-22 77.9 0.0 8.1e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EEB05970.1 - 6.8e-14 51.8 0.1 2e-13 50.4 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB05970.1 - 0.00025 21.1 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rtf2 PF04641.12 EEB05971.2 - 1.3e-61 208.2 1.5 1.9e-61 207.8 1.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EEB05971.2 - 1.5e-05 24.7 0.1 0.051 13.4 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EEB05971.2 - 0.00022 21.3 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_4 PF14447.6 EEB05971.2 - 0.0003 20.6 1.7 0.0017 18.2 0.0 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEB05971.2 - 0.011 15.8 2.2 0.029 14.4 0.8 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EEB05971.2 - 0.039 14.3 1.2 0.25 11.7 1.4 2.2 1 1 1 2 2 2 0 Ring finger domain PTR PF12789.7 EEB05971.2 - 0.64 10.1 7.1 0.96 9.6 4.4 2.5 2 1 0 2 2 2 0 Phage tail repeat like zf-RING_11 PF17123.5 EEB05971.2 - 1.4 8.8 4.4 0.8 9.5 0.5 2.3 2 0 0 2 2 2 0 RING-like zinc finger CDP-OH_P_transf PF01066.21 EEB05972.1 - 6e-14 52.6 0.7 6e-14 52.6 0.7 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 EEB05973.2 - 2e-28 99.5 0.0 2.4e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB05973.2 - 3.2e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB05973.2 - 7.9e-05 21.6 0.0 9.3e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEB05973.2 - 0.0076 15.6 0.4 0.016 14.6 0.4 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEB05973.2 - 0.023 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EEB05973.2 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EXS PF03124.14 EEB05974.1 - 2e-66 224.6 21.3 2.3e-66 224.4 21.3 1.0 1 0 0 1 1 1 1 EXS family Cpn60_TCP1 PF00118.24 EEB05975.1 - 1.9e-146 488.6 16.7 2.2e-146 488.4 16.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EEB05975.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Mon1 PF03164.14 EEB05976.1 - 1.8e-104 350.0 3.0 2.3e-104 349.7 3.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GRASP55_65 PF04495.14 EEB05977.1 - 6.4e-53 178.8 0.0 3.8e-44 150.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EEB05977.1 - 0.00043 20.5 0.0 0.039 14.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Hep_59 PF07052.11 EEB05978.1 - 1.3e-12 48.3 2.4 1.3e-12 48.3 2.4 2.9 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Peptidase_M3 PF01432.20 EEB05979.1 - 3e-129 432.3 0.0 4e-129 431.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EEB05979.1 - 0.11 12.2 0.5 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Peptidase M50B-like CwfJ_C_1 PF04677.15 EEB05980.1 - 2.7e-33 114.4 0.0 6e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EEB05980.1 - 9.2e-17 61.7 1.1 1.9e-16 60.7 0.3 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 EEB05980.1 - 4.2e-05 24.2 0.1 8.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 HIT domain Metallophos PF00149.28 EEB05980.1 - 0.0004 20.9 0.0 0.00074 20.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FKBP_C PF00254.28 EEB05981.1 - 1e-27 96.3 0.0 4.1e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EEB05981.1 - 1.8e-14 54.2 0.0 1.8e-14 54.2 0.0 3.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain Na_trans_assoc PF06512.13 EEB05981.1 - 0.00014 22.3 0.1 0.00014 22.3 0.1 2.5 1 1 1 2 2 2 1 Sodium ion transport-associated TFIIF_alpha PF05793.12 EEB05981.1 - 0.0017 17.1 54.2 0.0023 16.6 54.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PCM1_C PF15717.5 EEB05981.1 - 0.52 9.0 33.9 0.66 8.6 33.9 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus CCSAP PF15748.5 EEB05981.1 - 2.5 8.2 29.7 4.4 7.4 29.7 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Macoilin PF09726.9 EEB05981.1 - 2.6 6.5 21.5 3.2 6.2 21.5 1.0 1 0 0 1 1 1 0 Macoilin family Ribophorin_I PF04597.14 EEB05982.1 - 1.4e-108 364.0 2.0 1.6e-108 363.8 2.0 1.0 1 0 0 1 1 1 1 Ribophorin I DUF4247 PF14042.6 EEB05982.1 - 0.069 13.8 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Nramp PF01566.18 EEB05983.1 - 1.1e-89 300.9 9.9 1.1e-89 300.9 9.9 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein SF3b1 PF08920.10 EEB05984.1 - 6.8e-15 55.6 3.6 2.6e-14 53.7 3.6 2.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EEB05984.1 - 9.9e-14 51.5 9.9 0.0087 16.4 0.0 8.5 5 2 4 9 9 8 4 HEAT repeats HEAT_EZ PF13513.6 EEB05984.1 - 3.7e-13 49.7 2.6 0.1 13.2 0.0 8.0 7 1 0 7 7 7 3 HEAT-like repeat HEAT PF02985.22 EEB05984.1 - 3.7e-11 42.3 10.9 0.25 11.7 0.0 10.2 12 0 0 12 12 11 1 HEAT repeat DUF3385 PF11865.8 EEB05984.1 - 1.3e-06 28.4 3.7 0.036 14.0 0.1 5.3 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) NUC173 PF08161.12 EEB05984.1 - 2.2e-06 27.5 0.2 0.39 10.4 0.0 4.4 3 1 0 4 4 4 2 NUC173 domain Cnd1 PF12717.7 EEB05984.1 - 6.8e-06 26.2 11.6 1.1 9.3 0.2 6.3 6 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEB05984.1 - 0.00017 22.1 1.6 10 6.8 0.0 5.7 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EEB05984.1 - 0.00058 19.1 1.2 1.5 7.8 0.0 4.3 3 1 0 4 4 4 1 Dopey, N-terminal CLASP_N PF12348.8 EEB05984.1 - 0.001 18.7 1.3 1.9 8.0 0.1 3.5 3 0 0 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 EEB05984.1 - 0.0015 17.2 1.0 0.049 12.2 0.8 2.9 1 1 0 1 1 1 1 Adaptin N terminal region UNC45-central PF11701.8 EEB05984.1 - 0.0026 17.7 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central UME PF08064.13 EEB05984.1 - 0.0049 16.8 1.5 9.3 6.2 0.0 5.0 3 2 2 5 5 5 0 UME (NUC010) domain CRM1_C PF08767.11 EEB05984.1 - 0.022 13.9 0.1 0.052 12.7 0.1 1.6 1 0 0 1 1 1 0 CRM1 C terminal Tti2 PF10521.9 EEB05984.1 - 0.025 14.1 0.1 1.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Tti2 family MMTV_SAg PF01054.17 EEB05984.1 - 0.052 13.1 2.8 0.21 11.1 0.8 2.4 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen Arm PF00514.23 EEB05984.1 - 0.074 13.1 1.6 1.7e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1428 PF07237.11 EEB05984.1 - 0.089 13.1 0.1 0.34 11.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DRIM PF07539.12 EEB05984.1 - 0.092 11.0 2.5 7.4 4.7 0.1 4.1 2 1 1 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 EEB05984.1 - 0.14 11.3 0.1 53 2.7 0.3 3.9 3 1 2 5 5 5 0 RNAPII transcription regulator C-terminal PWWP PF00855.17 EEB05985.1 - 3.3e-08 33.8 0.0 7.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 PWWP domain Rep_fac_C PF08542.11 EEB05986.1 - 7.1e-17 61.6 0.3 1.6e-16 60.5 0.3 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EEB05986.1 - 1.1e-14 55.0 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEB05986.1 - 7.6e-13 48.6 0.0 9.2e-11 41.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EEB05986.1 - 3.4e-05 24.1 0.0 9.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 EEB05986.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EEB05986.1 - 0.00015 22.2 0.0 0.011 16.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EEB05986.1 - 0.0003 20.6 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EEB05986.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EEB05986.1 - 0.0011 18.8 0.1 0.0044 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EEB05986.1 - 0.0012 18.9 0.0 0.0064 16.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EEB05986.1 - 0.0016 18.7 0.1 0.096 13.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB05986.1 - 0.0016 18.8 0.2 0.029 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEB05986.1 - 0.0031 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EEB05986.1 - 0.0031 16.9 0.1 0.2 11.0 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EEB05986.1 - 0.0065 16.2 0.0 0.029 14.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEB05986.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEB05986.1 - 0.012 14.8 0.0 0.045 13.0 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 EEB05986.1 - 0.021 14.7 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB05986.1 - 0.027 14.5 0.1 0.14 12.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EEB05986.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 EEB05986.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.18 EEB05986.1 - 0.056 13.2 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase WSN PF02206.18 EEB05986.1 - 0.062 13.2 0.1 0.21 11.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function ResIII PF04851.15 EEB05986.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EEB05986.1 - 0.093 12.5 0.1 0.5 10.1 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EEB05986.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEB05986.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 EEB05987.1 - 1.8e-30 106.2 1.1 1.8e-30 106.2 1.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EEB05987.1 - 1.1e-07 30.5 0.8 2.1e-07 29.6 0.8 1.4 1 0 0 1 1 1 1 SBE2, cell-wall formation NAD_Gly3P_dh_N PF01210.23 EEB05988.1 - 6.5e-52 175.7 0.0 3.4e-51 173.3 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EEB05988.1 - 2.6e-45 154.2 0.1 5.3e-45 153.2 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EEB05988.1 - 0.0072 16.9 0.0 7 7.3 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NUP214 PF16755.5 EEB05989.1 - 1.7e-15 57.1 0.0 4.5e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Proteasome PF00227.26 EEB05990.1 - 2.3e-47 160.9 0.0 3e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EEB05990.1 - 2.8e-10 39.4 0.0 2.8e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal KH_1 PF00013.29 EEB05991.1 - 9.6e-07 28.5 0.0 6.1e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 KH domain ExbD PF02472.16 EEB05991.1 - 0.24 11.6 1.6 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 Biopolymer transport protein ExbD/TolR Actin PF00022.19 EEB05992.1 - 4.4e-134 447.1 0.0 5.5e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEB05992.1 - 0.0035 16.2 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Glyco_hydro81C PF17652.1 EEB05993.1 - 9.3e-147 488.8 6.3 1.4e-146 488.2 6.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEB05993.1 - 3.4e-86 289.4 4.8 1.5e-47 162.3 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 N-terminal domain UQ_con PF00179.26 EEB05994.1 - 1.1e-37 128.8 0.0 1.3e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aminotran_3 PF00202.21 EEB05995.1 - 1.9e-108 362.7 0.0 3.2e-108 362.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Nterm_IS4 PF13006.7 EEB05995.1 - 0.08 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal HbrB PF08539.11 EEB05996.1 - 3e-39 134.7 0.5 5.1e-39 134.0 0.5 1.4 1 0 0 1 1 1 1 HbrB-like Glyco_transf_15 PF01793.16 EEB05997.1 - 8.3e-112 373.6 5.3 1e-111 373.3 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Shigella_OspC PF06128.11 EEB05997.1 - 0.0069 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Shigella flexneri OspC protein WD40 PF00400.32 EEB05998.1 - 3.4e-45 151.1 23.6 1.7e-07 31.8 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EEB05998.1 - 2.4e-11 43.3 3.5 5.3e-11 42.2 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEB05998.1 - 5.2e-11 42.1 0.4 1.3e-10 40.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EEB05998.1 - 1.1e-10 41.6 1.4 0.0095 16.2 0.1 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB05998.1 - 5.9e-08 31.8 6.6 0.0034 16.1 0.1 4.5 3 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EEB05998.1 - 8.1e-06 25.8 0.2 0.076 13.1 0.0 5.1 5 1 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EEB05998.1 - 8.4e-06 25.3 0.5 0.094 12.0 0.1 2.9 2 1 1 3 3 3 3 WD40-like domain Nucleoporin_N PF08801.11 EEB05998.1 - 0.0095 14.7 2.3 5 5.8 0.0 4.2 4 1 0 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EEB05998.1 - 0.013 14.4 0.2 0.18 10.7 0.0 2.7 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF5046 PF16465.5 EEB05998.1 - 0.085 12.3 0.0 22 4.4 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) Tudor_2 PF18104.1 EEB05998.1 - 0.091 12.5 0.3 0.23 11.2 0.3 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain CDtoxinA PF03498.14 EEB05998.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain HTH_40 PF14493.6 EEB05998.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 EEB05999.1 - 2.3e-52 177.1 0.1 8.5e-30 104.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEB05999.1 - 3.8e-41 141.6 35.5 9e-24 84.6 13.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EEB05999.1 - 1.6e-13 50.6 3.7 4.5e-05 23.0 1.4 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEB05999.1 - 4e-08 34.0 0.1 7.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EEB05999.1 - 1.6e-07 31.4 3.8 0.039 13.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EEB05999.1 - 1.8e-06 28.4 0.3 0.063 13.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EEB05999.1 - 2.7e-06 27.0 7.5 0.0022 17.7 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEB05999.1 - 2.7e-06 27.4 0.1 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EEB05999.1 - 7.3e-06 25.6 0.0 0.08 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EEB05999.1 - 1.4e-05 24.8 0.3 0.26 10.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EEB05999.1 - 2.2e-05 24.5 3.0 0.12 12.4 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEB05999.1 - 3.8e-05 23.8 0.2 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 EEB05999.1 - 0.00017 21.9 0.1 0.78 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 EEB05999.1 - 0.00022 20.4 0.1 0.43 9.6 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 EEB05999.1 - 0.0014 18.8 6.7 0.023 14.8 0.9 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EEB05999.1 - 0.0019 17.6 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA PF00004.29 EEB05999.1 - 0.0048 17.3 0.8 2.2 8.7 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EEB05999.1 - 0.0066 16.2 0.2 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EEB05999.1 - 0.013 15.7 0.0 6.4 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEB05999.1 - 0.016 15.0 1.3 9.2 6.0 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 EEB05999.1 - 0.023 14.7 0.3 4.9 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EEB05999.1 - 0.025 13.9 0.7 3.7 6.8 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 EEB05999.1 - 0.027 14.2 0.4 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEB05999.1 - 0.031 14.8 0.0 12 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EEB05999.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEB05999.1 - 0.041 13.6 0.5 5.3 6.7 0.3 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EEB05999.1 - 0.049 13.3 0.1 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EEB05999.1 - 0.064 12.5 0.1 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Guanylate_kin PF00625.21 EEB05999.1 - 0.13 11.9 0.3 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase Roc PF08477.13 EEB05999.1 - 0.15 12.3 0.4 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EEB05999.1 - 0.2 10.8 0.1 7.9 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EEB05999.1 - 0.22 10.7 0.2 13 4.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 EEB05999.1 - 0.27 10.4 0.1 7.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EEB05999.1 - 1.5 8.6 4.0 26 4.5 0.0 3.3 4 0 0 4 4 3 0 DEAD/DEAH box helicase cobW PF02492.19 EEB05999.1 - 1.9 8.0 5.6 6.3 6.3 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 EEB05999.1 - 4 6.7 7.5 9.3 5.5 0.4 3.1 3 0 0 3 3 3 0 AIG1 family Translin PF01997.16 EEB06000.1 - 5.7e-38 131.0 0.4 6.7e-38 130.7 0.4 1.0 1 0 0 1 1 1 1 Translin family DUF3732 PF12532.8 EEB06000.1 - 0.039 13.5 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) DUF737 PF05300.11 EEB06000.1 - 0.089 13.1 0.8 0.12 12.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) RPW8 PF05659.11 EEB06000.1 - 0.21 11.3 3.7 6.5 6.4 0.0 3.3 2 2 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NPV_P10 PF05531.12 EEB06000.1 - 0.39 11.2 6.0 2.7 8.5 0.3 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EEB06000.1 - 0.39 10.7 2.8 1.3 9.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EEB06000.1 - 0.42 10.7 2.6 10 6.2 2.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EEB06000.1 - 0.55 10.2 3.4 3.6 7.6 1.9 2.2 2 0 0 2 2 2 0 Laminin Domain II KTI12 PF08433.10 EEB06001.1 - 1.2e-93 313.5 0.0 1.3e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EEB06001.1 - 0.0009 19.4 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEB06001.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec7 PF01369.20 EEB06002.1 - 1.2e-71 240.2 4.2 2.2e-71 239.3 1.2 3.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 EEB06002.1 - 4.5e-37 127.4 7.6 4.5e-37 127.4 7.6 5.0 4 2 1 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EEB06002.1 - 9e-36 121.6 15.1 7.4e-32 109.1 2.2 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 EEB06002.1 - 3.2e-07 30.2 7.0 5.2e-07 29.5 0.9 3.7 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 La PF05383.17 EEB06003.1 - 3.5e-10 39.8 0.0 7.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 La domain Macoilin PF09726.9 EEB06003.1 - 1.5 7.3 21.1 0.097 11.2 1.4 2.1 2 0 0 2 2 2 0 Macoilin family Got1 PF04178.12 EEB06004.1 - 1.3e-25 90.0 19.4 1.8e-25 89.6 19.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Hep_core_N PF08290.11 EEB06004.1 - 0.28 11.2 2.9 0.89 9.6 2.9 1.9 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger DUF2070 PF09843.9 EEB06004.1 - 0.66 8.2 12.5 0.76 8.0 12.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3671 PF12420.8 EEB06004.1 - 5.6 7.1 5.6 2.1 8.5 2.9 1.6 1 1 1 2 2 2 0 Protein of unknown function Alpha-amylase PF00128.24 EEB06005.2 - 5e-19 69.0 5.0 4.5e-14 52.7 0.2 4.3 4 1 0 4 4 4 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EEB06005.2 - 1.5e-10 41.2 0.1 4.4e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EEB06005.2 - 7e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.6 EEB06005.2 - 0.0041 17.8 0.2 0.012 16.3 0.2 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain Glyco_transf_4 PF13439.6 EEB06005.2 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Alpha-amylase PF00128.24 EEB06006.2 - 2e-47 162.4 0.6 3e-47 161.8 0.6 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EEB06006.2 - 3.8e-09 36.7 0.0 9.1e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Sec7_N PF12783.7 EEB06007.2 - 3.1e-36 124.7 1.0 3.1e-36 124.7 1.0 5.1 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EEB06007.2 - 9.3e-30 103.6 2.4 9.3e-30 103.6 2.4 3.1 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EEB06007.2 - 1.2e-15 56.8 6.4 2e-15 56.1 3.8 2.5 2 1 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EEB06007.2 - 1.7e-05 24.6 12.1 0.0016 18.3 0.1 6.1 6 1 0 6 6 6 2 Domain of unknown function (DUF1981) Sugar_tr PF00083.24 EEB06010.1 - 2.1e-41 142.2 13.0 3e-41 141.7 13.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB06010.1 - 5.1e-20 71.7 15.4 5.1e-20 71.7 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEB06010.1 - 3.1e-08 33.3 2.0 6.4e-08 32.3 2.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB adh_short PF00106.25 EEB06011.2 - 1.1e-43 149.0 0.1 1.6e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB06011.2 - 3.6e-31 108.5 0.0 6.6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB06011.2 - 3.4e-07 30.3 0.1 7.1e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEB06011.2 - 0.00014 21.8 1.3 0.00017 21.6 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EEB06011.2 - 0.0035 16.8 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EEB06011.2 - 0.013 14.8 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) ParBc PF02195.18 EEB06011.2 - 0.015 15.6 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 ParB-like nuclease domain TrkA_N PF02254.18 EEB06011.2 - 0.015 15.5 0.8 0.084 13.1 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain NmrA PF05368.13 EEB06011.2 - 0.015 14.8 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EEB06011.2 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_pol_lambd_f PF10391.9 EEB06011.2 - 0.18 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Thioredoxin PF00085.20 EEB06012.1 - 3.7e-05 23.6 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Vps35 PF03635.17 EEB06013.1 - 2e-248 826.7 26.7 2.3e-248 826.5 26.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TnsD PF15978.5 EEB06013.1 - 0.04 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Tn7-like transposition protein D Pkinase PF00069.25 EEB06014.1 - 7e-53 179.7 0.2 1.1e-52 179.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06014.1 - 1.5e-20 73.5 1.4 9.8e-20 70.9 0.4 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EEB06014.1 - 0.0078 15.8 1.1 0.18 11.4 0.0 2.4 1 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EEB06014.1 - 0.17 10.6 7.5 0.58 8.9 7.5 1.7 1 1 0 1 1 1 0 Fungal protein kinase Herpes_UL32 PF06070.11 EEB06014.1 - 1.3 6.6 5.5 1.8 6.2 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Presenilin PF01080.17 EEB06014.1 - 2.4 6.8 3.9 3.4 6.3 3.9 1.2 1 0 0 1 1 1 0 Presenilin Dus PF01207.17 EEB06015.1 - 8.9e-70 235.2 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.24 EEB06015.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HH_signal PF01085.18 EEB06015.1 - 0.099 12.3 0.0 14 5.3 0.0 3.0 2 1 1 3 3 3 0 Hedgehog amino-terminal signalling domain Acetyltransf_3 PF13302.7 EEB06016.2 - 4.8e-17 62.9 0.0 6.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB06016.2 - 1.5e-06 28.4 0.0 2.6e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EEB06016.2 - 3.8e-05 23.4 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEB06016.2 - 0.018 15.2 0.0 0.043 14.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ubie_methyltran PF01209.18 EEB06017.1 - 1.2e-83 280.0 0.0 1.5e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EEB06017.1 - 4.4e-14 52.9 0.0 8.8e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB06017.1 - 3e-12 47.0 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB06017.1 - 8.7e-12 45.1 0.0 4.4e-11 42.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB06017.1 - 1.7e-10 41.5 0.1 2.9e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB06017.1 - 4.7e-06 26.5 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EEB06017.1 - 0.0051 16.7 0.1 0.044 13.6 0.0 2.4 3 0 0 3 3 3 1 Hypothetical methyltransferase ERCC4 PF02732.15 EEB06018.1 - 2.4e-23 83.1 2.3 6e-23 81.8 2.3 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EEB06018.1 - 0.1 13.0 0.0 0.41 11.1 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain MRP-L47 PF06984.13 EEB06019.1 - 7.9e-32 109.2 0.8 1.2e-31 108.6 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) PHD PF00628.29 EEB06020.1 - 5.5e-09 35.8 11.6 9.5e-09 35.0 11.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEB06020.1 - 0.013 15.0 11.7 0.061 12.9 11.7 2.1 1 1 0 1 1 1 0 PHD-finger zf-RRPl_C4 PF17026.5 EEB06020.1 - 0.23 11.6 4.2 0.51 10.5 4.2 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE_2 PF02318.16 EEB06020.1 - 0.32 11.2 3.1 0.62 10.3 3.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrom_c3_2 PF14537.6 EEB06020.1 - 0.48 10.9 7.2 0.1 13.1 1.8 2.4 1 1 1 2 2 2 0 Cytochrome c3 C1_1 PF00130.22 EEB06020.1 - 1.2 9.1 10.6 0.45 10.4 6.3 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EEB06020.1 - 1.6 8.3 11.7 0.23 11.0 7.1 2.0 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.25 EEB06021.1 - 2.7e-68 230.2 0.0 3.6e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06021.1 - 4.9e-30 104.7 0.0 6.6e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEB06021.1 - 4.4e-07 30.5 1.0 1.1e-06 29.2 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEB06021.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEB06021.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EEB06021.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 EEB06022.1 - 1.3e-33 116.5 0.0 3.2e-33 115.2 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain BHD_3 PF10405.9 EEB06023.1 - 4.1e-28 97.6 0.1 8.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EEB06023.1 - 1.9e-23 82.8 1.0 5e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EEB06023.1 - 4.8e-19 67.9 0.1 8.9e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EEB06023.1 - 1.6e-14 54.6 0.4 1.6e-14 54.6 0.4 2.7 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EEB06023.1 - 4.8e-05 23.8 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3246 PF11596.8 EEB06023.1 - 1.2 8.5 5.2 2 7.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2418 PF10332.9 EEB06024.1 - 1.2e-29 102.7 1.0 1.2e-29 102.7 1.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2418) Sigma_reg_N PF13800.6 EEB06024.1 - 0.012 15.9 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CUE PF02845.16 EEB06025.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3328 PF11807.8 EEB06025.1 - 0.21 11.4 1.3 0.26 11.0 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) G2BR PF18442.1 EEB06025.1 - 2.1 8.1 9.1 3.5 7.3 9.1 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DnaJ_C PF01556.18 EEB06026.1 - 2.8e-37 128.1 0.0 4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEB06026.1 - 3.7e-24 84.6 7.9 6.8e-24 83.8 4.5 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEB06026.1 - 6.6e-11 42.4 19.8 1.3e-10 41.5 19.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EEB06026.1 - 3.2 7.8 9.5 29 4.7 9.5 2.4 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C2HC5 PF06221.13 EEB06026.1 - 3.6 7.7 6.2 0.9 9.6 2.4 2.0 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Anti-TRAP PF15777.5 EEB06026.1 - 4.1 7.4 18.2 4.7 7.2 4.7 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 EEB06026.1 - 6.5 7.0 9.2 3.5 7.8 0.7 3.3 2 1 1 3 3 3 0 Zinc ribbon domain HypA PF01155.19 EEB06026.1 - 6.5 6.8 8.4 15 5.6 1.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOT2_3_5 PF04153.18 EEB06027.2 - 1e-31 109.8 0.9 1e-31 109.8 0.9 1.6 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Inv-AAD PF18785.1 EEB06028.1 - 3.6e-27 94.8 0.3 1.1e-26 93.2 0.3 1.6 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EEB06028.1 - 2.7e-22 78.5 0.1 4.4e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEB06028.1 - 4.6e-06 26.4 0.1 5.6e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase HD_3 PF13023.6 EEB06029.1 - 7.8e-46 156.0 0.8 9.5e-46 155.7 0.8 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EEB06029.1 - 6.6e-12 45.5 0.8 8.5e-12 45.2 0.8 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EEB06029.1 - 3.4e-05 24.0 0.3 6.9e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 HD domain FliL PF03748.14 EEB06029.1 - 0.054 14.1 0.0 0.09 13.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL CENP-M PF11111.8 EEB06029.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) RIX1 PF08167.12 EEB06030.1 - 7.8e-48 162.7 3.1 7.8e-48 162.7 3.1 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF4965 PF16335.5 EEB06030.1 - 0.042 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) DUF1286 PF06939.11 EEB06030.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) FA_desaturase PF00487.24 EEB06031.1 - 3.4e-21 76.2 12.2 3.4e-21 76.2 12.2 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 EEB06031.1 - 2.5e-17 62.1 0.7 4.3e-17 61.3 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Diphthamide_syn PF01866.17 EEB06032.1 - 2.4e-122 408.2 0.0 2.8e-122 407.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribonuc_L-PSP PF01042.21 EEB06032.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Endoribonuclease L-PSP SPX PF03105.19 EEB06033.1 - 1.6e-37 130.4 8.3 2.9e-24 86.7 3.3 2.2 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 EEB06033.1 - 2.9e-34 118.6 52.8 2.2e-29 102.6 27.3 2.5 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EEB06033.1 - 1.7e-28 99.9 32.3 2.3e-28 99.5 32.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CENP-B_dimeris PF09026.10 EEB06033.1 - 4.2e-05 23.9 4.4 8.7e-05 22.8 4.4 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DLP_helical PF18709.1 EEB06033.1 - 0.024 13.9 0.6 0.039 13.2 0.6 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain TFIIA_gamma_N PF02268.16 EEB06033.1 - 0.029 14.4 0.2 0.13 12.3 0.0 2.2 3 0 0 3 3 2 0 Transcription initiation factor IIA, gamma subunit, helical domain FAM176 PF14851.6 EEB06033.1 - 0.031 13.9 1.4 0.09 12.4 1.4 1.7 1 0 0 1 1 1 0 FAM176 family CDC37_C PF08564.10 EEB06033.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.1 2 0 0 2 2 2 0 Cdc37 C terminal domain NOA36 PF06524.12 EEB06033.1 - 0.057 12.7 8.3 0.083 12.2 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EEB06033.1 - 0.11 12.3 10.9 0.19 11.4 10.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EEB06033.1 - 0.33 11.2 6.9 0.94 9.7 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Mt_ATP-synt_B PF05405.14 EEB06033.1 - 0.66 9.6 3.5 4.2 7.0 0.2 2.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pox_Ag35 PF03286.14 EEB06033.1 - 1.8 8.4 5.5 3.8 7.3 5.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3245 PF11595.8 EEB06033.1 - 2.3 8.7 5.3 4.6 7.7 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DNA_pol_phi PF04931.13 EEB06033.1 - 5.9 4.9 12.6 11 4.0 12.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 EEB06033.1 - 7.2 6.5 12.4 11 5.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sacchrp_dh_C PF16653.5 EEB06034.1 - 1.7e-89 300.4 0.0 2.5e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EEB06034.1 - 4.4e-28 98.1 0.4 6.6e-28 97.6 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EEB06034.1 - 5.7e-07 29.6 0.2 1e-06 28.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EEB06034.1 - 5.3e-06 26.5 0.0 9.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 EEB06034.1 - 0.00027 20.0 0.2 0.00039 19.5 0.2 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EEB06034.1 - 0.0015 19.3 0.7 0.0042 17.9 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EEB06034.1 - 0.043 14.5 0.2 0.081 13.6 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EEB06034.1 - 0.055 14.1 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EEB06034.1 - 0.072 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EEB06034.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.23 EEB06035.1 - 8.4e-16 58.0 0.3 1.3e-15 57.4 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB06035.1 - 6e-12 46.1 0.4 6e-12 46.1 0.4 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EEB06035.1 - 0.14 12.5 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pyr_redox_2 PF07992.14 EEB06036.2 - 4e-10 39.4 0.0 1.9e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEB06036.2 - 0.00032 20.9 0.0 0.00073 19.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EEB06036.2 - 0.0052 16.1 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 EEB06036.2 - 0.0098 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EEB06036.2 - 0.17 11.0 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) RRM_1 PF00076.22 EEB06037.1 - 1e-16 60.5 0.0 1.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 EEB06038.1 - 9.3e-05 20.4 14.2 0.024 12.5 4.8 5.1 5 1 1 6 6 6 3 Nuclear pore component Spc7 PF08317.11 EEB06038.1 - 0.0087 15.0 2.7 0.012 14.5 0.1 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein ASXH PF13919.6 EEB06039.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Asx homology domain Rad21_Rec8_N PF04825.13 EEB06040.1 - 6.7e-26 90.6 0.2 1.4e-25 89.6 0.2 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EEB06040.1 - 4.4e-12 45.1 0.1 8.8e-12 44.1 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein F-box-like PF12937.7 EEB06041.1 - 2.9e-09 36.7 0.7 1.2e-08 34.7 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EEB06041.1 - 6.7e-08 32.2 0.2 6.7e-08 32.2 0.2 2.8 3 0 0 3 3 3 1 F-box domain FBD PF08387.10 EEB06041.1 - 0.0052 16.6 0.3 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 FBD LRR_6 PF13516.6 EEB06041.1 - 0.0078 16.2 3.1 2.4 8.4 0.0 4.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 EEB06041.1 - 0.015 15.7 16.7 0.048 14.1 0.1 6.1 3 3 5 8 8 8 0 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 EEB06041.1 - 0.03 14.4 2.4 3.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06041.1 - 0.054 13.3 3.0 4.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 EEB06041.1 - 0.07 13.7 2.8 45 5.2 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EEB06041.1 - 0.1 12.4 2.0 2.9 7.7 0.1 3.3 2 1 0 2 2 2 0 Leucine rich repeat DDOST_48kD PF03345.14 EEB06042.1 - 7.9e-130 433.4 0.0 9.2e-130 433.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1647 PF07801.11 EEB06042.1 - 0.099 12.4 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) PfkB PF00294.24 EEB06043.1 - 1.6e-74 251.0 2.4 1.9e-74 250.7 2.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEB06043.1 - 3.1e-06 26.8 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase COG4 PF08318.12 EEB06044.1 - 8e-79 265.1 0.1 1.7e-78 264.1 0.1 1.6 1 0 0 1 1 1 1 COG4 transport protein Rx_N PF18052.1 EEB06044.1 - 0.0042 17.3 1.2 6.7 7.1 0.0 3.1 2 0 0 2 2 2 2 Rx N-terminal domain Rep_fac_C PF08542.11 EEB06044.1 - 0.02 15.3 0.5 0.086 13.3 0.5 2.1 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF2400 PF09674.10 EEB06044.1 - 0.21 11.6 5.0 0.94 9.4 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2400) Inhibitor_I9 PF05922.16 EEB06045.1 - 1.6e-12 47.9 0.0 3.5e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 Band_7 PF01145.25 EEB06046.1 - 7.6e-22 78.2 1.0 1e-21 77.7 1.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family FbpA PF05833.11 EEB06047.1 - 7.9e-32 110.6 23.6 7.1e-25 87.7 0.0 3.1 2 1 1 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EEB06047.1 - 3.8e-27 95.1 0.0 1.1e-26 93.5 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 EEB06047.1 - 3.5e-15 55.8 0.2 3.5e-15 55.8 0.2 2.7 2 0 0 2 2 2 1 NFACT protein C-terminal domain RQC PF09382.10 EEB06047.1 - 0.027 14.2 0.3 0.15 11.9 0.1 2.3 2 0 0 2 2 2 0 RQC domain DUF3037 PF11236.8 EEB06047.1 - 0.045 14.2 3.7 0.53 10.7 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) CvfB_WH PF17783.1 EEB06047.1 - 0.063 13.1 0.4 0.21 11.4 0.4 1.9 1 0 0 1 1 1 0 CvfB-like winged helix domain SIR2 PF02146.17 EEB06048.2 - 1.3e-55 188.1 0.0 1.8e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EEB06048.2 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ZZ PF00569.17 EEB06048.2 - 0.16 11.8 2.4 0.37 10.6 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF4452 PF14618.6 EEB06049.2 - 0.0011 18.8 0.5 0.0011 18.8 0.5 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Lzipper-MIP1 PF14389.6 EEB06049.2 - 0.015 15.6 0.9 0.045 14.1 0.9 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TAF1D PF15333.6 EEB06049.2 - 0.041 13.6 0.5 0.041 13.6 0.5 2.5 2 1 0 2 2 2 0 TATA box-binding protein-associated factor 1D Ribosomal_60s PF00428.19 EEB06049.2 - 1.7 9.3 11.1 0.88 10.2 8.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SKA1 PF07160.12 EEB06049.2 - 3 7.6 12.3 0.14 12.0 4.6 2.1 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 COX4 PF02936.14 EEB06050.1 - 2.6e-42 144.1 0.0 3.3e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 EEB06050.1 - 0.019 15.3 0.4 0.046 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) N1221 PF07923.13 EEB06050.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein DUF1289 PF06945.13 EEB06050.1 - 0.23 11.3 2.0 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Cation_efflux PF01545.21 EEB06051.2 - 6.6e-52 176.1 2.2 8.5e-52 175.8 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2663 PF10864.8 EEB06051.2 - 0.2 12.0 0.4 0.72 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Methyltransf_16 PF10294.9 EEB06052.1 - 1.8e-18 66.9 0.0 3.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEB06052.1 - 3.5e-05 23.7 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB06052.1 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB06052.1 - 0.0032 18.1 0.0 0.009 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB06052.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L34e PF01199.18 EEB06053.1 - 1.6e-41 140.5 2.6 2.1e-41 140.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e VTC PF09359.10 EEB06054.1 - 3.1e-98 328.5 0.1 5.4e-98 327.8 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EEB06054.1 - 1.6e-13 51.3 28.1 9.6e-07 29.1 0.0 4.3 3 2 1 4 4 4 3 SPX domain DUF202 PF02656.15 EEB06054.1 - 6.5e-09 36.1 3.0 6.5e-09 36.1 3.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2630 PF10944.8 EEB06054.1 - 0.045 14.2 0.6 0.44 11.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) EnY2 PF10163.9 EEB06054.1 - 1.3 9.5 4.0 1.1 9.7 1.9 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 AIRC PF00731.20 EEB06055.1 - 1.2e-66 222.8 1.1 2.9e-66 221.6 1.1 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EEB06055.1 - 9.7e-63 210.8 0.0 1.7e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EEB06055.1 - 6.4e-19 67.4 0.0 1.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EEB06055.1 - 9.7e-07 28.5 0.0 3.6e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EEB06055.1 - 1.6e-06 27.8 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EEB06055.1 - 9.9e-05 22.4 0.0 0.00035 20.6 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 EEB06055.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 EEB06055.1 - 0.047 13.3 0.2 0.34 10.5 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator CoA_binding_2 PF13380.6 EEB06055.1 - 0.074 13.5 0.4 14 6.2 0.0 3.1 2 1 1 3 3 3 0 CoA binding domain AlaDh_PNT_C PF01262.21 EEB06055.1 - 0.16 11.2 1.8 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Mad3_BUB1_I PF08311.12 EEB06056.1 - 1.8e-31 108.7 2.8 3.8e-31 107.7 2.8 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EEB06056.1 - 8.6e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06056.1 - 5.1e-07 29.2 0.0 8.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 EEB06056.1 - 0.034 14.3 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 DRIM PF07539.12 EEB06057.2 - 0.0021 16.4 0.7 0.012 14.0 0.8 2.0 1 1 1 2 2 2 2 Down-regulated in metastasis Pkinase PF00069.25 EEB06058.1 - 3.9e-72 242.8 0.0 8.1e-72 241.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06058.1 - 5.7e-31 107.7 0.0 1.5e-30 106.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06058.1 - 0.00059 19.2 0.8 0.6 9.4 0.1 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EEB06058.1 - 0.002 17.0 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEB06058.1 - 0.003 16.9 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEB06058.1 - 0.0056 16.3 0.8 0.035 13.7 0.8 2.2 1 1 0 1 1 1 1 RIO1 family SBDS_C PF09377.10 EEB06058.1 - 0.079 13.0 0.0 1.3 9.1 0.0 2.5 2 1 0 2 2 2 0 SBDS protein C-terminal domain ABC1 PF03109.16 EEB06058.1 - 0.082 13.1 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Cloacin PF03515.14 EEB06058.1 - 0.085 12.5 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain DUF5427 PF10310.9 EEB06059.1 - 8.4e-64 216.2 15.4 6.1e-63 213.4 15.4 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF5427) Caprin-1_dimer PF18293.1 EEB06059.1 - 0.021 15.3 2.9 0.3 11.6 0.4 2.7 2 0 0 2 2 2 0 Caprin-1 dimerization domain Cohesin_HEAT PF12765.7 EEB06059.1 - 0.11 12.8 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Hid1 PF12722.7 EEB06059.1 - 1 7.4 9.3 1.5 6.8 9.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Caskin-tail PF16632.5 EEB06059.1 - 3.4 8.1 5.3 3.8 8.0 0.2 3.5 4 0 0 4 4 4 0 C-terminal region of Caskin GPI-anchored PF10342.9 EEB06060.1 - 2.4e-12 47.4 0.1 4.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_L14 PF00238.19 EEB06061.1 - 3.6e-36 123.9 0.0 4.4e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peptidase_M1 PF01433.20 EEB06062.1 - 4.5e-49 167.0 0.0 6.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EEB06062.1 - 4.2e-38 129.9 0.1 7.6e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EEB06062.1 - 2.3e-30 106.1 0.0 3.6e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EEB06062.1 - 0.28 11.6 1.1 2.6 8.5 1.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase UDPGP PF01704.18 EEB06063.1 - 2.5e-194 645.6 0.1 2.9e-194 645.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TRP PF06011.12 EEB06064.2 - 1.1e-29 103.4 40.5 1.1e-29 103.4 40.5 2.5 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel RTA1 PF04479.13 EEB06067.1 - 7.4e-24 84.5 0.5 1.2e-23 83.8 0.5 1.3 1 0 0 1 1 1 1 RTA1 like protein Sre PF03125.18 EEB06067.1 - 0.026 13.7 4.7 0.035 13.2 0.0 2.0 1 1 1 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor AA_permease_2 PF13520.6 EEB06068.1 - 1.7e-52 178.7 54.3 2.1e-52 178.4 54.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB06068.1 - 2.9e-16 59.1 44.9 4e-16 58.7 44.9 1.2 1 0 0 1 1 1 1 Amino acid permease PHD PF00628.29 EEB06070.1 - 4.8e-16 58.4 23.8 4.8e-10 39.2 7.8 3.2 2 1 1 3 3 3 3 PHD-finger PHF12_MRG_bd PF16737.5 EEB06070.1 - 0.11 12.3 0.5 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 EEB06070.1 - 0.63 9.6 19.7 0.53 9.9 0.4 4.1 3 1 0 3 3 3 0 PHD-finger C1_1 PF00130.22 EEB06070.1 - 0.77 9.7 18.8 0.1 12.5 3.0 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF5 PF04855.12 EEB06071.1 - 2e-28 99.8 0.1 3.3e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DHHC PF01529.20 EEB06072.2 - 1.3e-30 106.2 14.7 1.3e-30 106.2 14.7 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 EEB06072.2 - 2.2e-17 63.2 1.2 1.5e-07 31.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB06072.2 - 3.4e-16 59.6 5.4 1.8e-07 31.7 0.3 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB06072.2 - 2e-14 53.5 3.9 5.4e-07 29.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EEB06072.2 - 2.6e-11 43.4 13.2 1.9e-05 24.9 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EEB06072.2 - 2.9e-09 36.4 9.4 0.0002 21.5 0.1 5.6 6 0 0 6 6 6 2 Ankyrin repeat HMG_box PF00505.19 EEB06074.1 - 0.08 13.4 1.7 0.17 12.3 0.6 2.1 1 1 1 2 2 2 0 HMG (high mobility group) box RhoGAP PF00620.27 EEB06075.1 - 2.1e-36 125.0 0.0 5.1e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EEB06075.1 - 1.9e-08 34.4 0.1 1.9e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain ING PF12998.7 EEB06075.1 - 0.024 15.2 2.7 0.081 13.5 0.0 2.7 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CMS1 PF14617.6 EEB06076.1 - 4.7e-42 144.1 8.8 5.1e-42 143.9 8.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EEB06076.1 - 5.8e-08 32.7 0.1 8.4e-08 32.2 0.1 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase MMM1 PF10296.9 EEB06077.1 - 8.2e-09 35.0 0.1 8.2e-09 35.0 0.1 2.9 2 2 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EEB06077.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain SUI1 PF01253.22 EEB06078.1 - 4.8e-28 97.5 0.3 5.9e-28 97.2 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Sel1 PF08238.12 EEB06079.1 - 5e-05 23.8 0.0 0.19 12.5 0.0 3.9 4 0 0 4 4 4 2 Sel1 repeat OGG_N PF07934.12 EEB06080.1 - 4.7e-24 84.8 0.4 8.1e-24 84.0 0.4 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EEB06080.1 - 4.6e-11 43.1 0.0 7.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ctr PF04145.15 EEB06080.1 - 9.8e-11 42.5 7.7 1.6e-05 25.6 4.0 2.4 1 1 1 2 2 2 2 Ctr copper transporter family HHH PF00633.23 EEB06080.1 - 2.6e-05 23.8 0.0 6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EEB06080.1 - 0.091 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Romo1 PF10247.9 EEB06081.1 - 8.8e-27 93.3 9.2 1.1e-26 92.9 9.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Polysacc_synt_C PF14667.6 EEB06081.1 - 0.051 13.6 0.3 0.065 13.3 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Tim17 PF02466.19 EEB06081.1 - 0.17 12.3 3.3 0.27 11.6 3.3 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Aha1_N PF09229.11 EEB06082.1 - 8.5e-35 119.9 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EEB06082.1 - 3.4e-16 59.6 0.0 5.1e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein WD40 PF00400.32 EEB06083.1 - 1.4e-18 66.9 6.2 1.4e-06 28.9 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EEB06083.1 - 1.9e-16 60.1 0.1 6.3e-15 55.2 0.0 3.0 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EEB06083.1 - 3.7e-10 40.0 1.4 0.00038 20.7 0.0 4.5 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB06083.1 - 0.0068 16.3 0.4 2.9 7.7 0.1 3.3 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DeoRC PF00455.22 EEB06083.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain Myosin-VI_CBD PF16521.5 EEB06083.1 - 0.028 14.4 0.0 2.6 8.1 0.0 2.7 1 1 1 2 2 2 0 Myosin VI cargo binding domain BUD22 PF09073.10 EEB06083.1 - 9.3 5.5 9.5 12 5.1 9.5 1.1 1 0 0 1 1 1 0 BUD22 SRP40_C PF05022.12 EEB06085.1 - 9.7e-27 93.6 3.1 9.7e-27 93.6 3.1 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 EEB06085.1 - 0.0035 17.2 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 LisH THF_DHG_CYH PF00763.23 EEB06086.1 - 5.1e-22 78.3 0.0 9.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EEB06086.1 - 3.3e-15 55.8 0.1 6.2e-10 38.6 0.0 2.8 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EEB06086.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EMC3_TMCO1 PF01956.16 EEB06087.1 - 6.1e-52 175.8 0.4 7.7e-52 175.5 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ribosomal_60s PF00428.19 EEB06088.1 - 1e-24 87.0 19.0 1.3e-24 86.6 19.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 EEB06088.1 - 0.95 10.1 5.2 1.5 9.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) E1-E2_ATPase PF00122.20 EEB06089.1 - 2.3e-44 151.1 5.0 5.1e-43 146.7 3.9 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEB06089.1 - 1.6e-18 67.8 0.0 4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEB06089.1 - 1.6e-09 37.3 0.0 3.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEB06089.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEB06089.1 - 0.0026 17.6 0.1 0.0056 16.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2818 PF10993.8 EEB06089.1 - 0.35 11.5 3.7 0.23 12.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) DUF2613 PF11021.8 EEB06089.1 - 2.8 8.1 8.0 3.9 7.7 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Comm PF15957.5 EEB06089.1 - 7.8 6.9 8.0 13 6.1 1.1 3.1 3 0 0 3 3 3 0 Commissureless Mod_r PF07200.13 EEB06090.1 - 0.053 13.6 9.6 0.094 12.8 9.6 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 EEB06090.1 - 0.085 12.4 5.4 0.093 12.3 5.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1204 PF06721.11 EEB06090.1 - 0.16 11.4 3.4 0.48 9.8 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) AAA PF00004.29 EEB06091.1 - 6.6e-44 149.5 0.0 1.7e-43 148.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB06091.1 - 2.2e-14 53.0 0.1 5.2e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EEB06091.1 - 2.4e-08 34.3 0.0 5.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEB06091.1 - 3.2e-08 34.2 0.2 3.2e-06 27.6 0.1 3.3 2 1 0 2 2 1 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EEB06091.1 - 6e-08 32.5 0.8 1.4e-07 31.4 0.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EEB06091.1 - 4e-07 30.1 0.0 1.4e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEB06091.1 - 6.2e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB06091.1 - 7.5e-05 23.0 1.9 0.012 15.9 0.0 2.9 3 1 1 4 4 2 1 AAA domain AAA_33 PF13671.6 EEB06091.1 - 0.00099 19.3 0.0 0.0034 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EEB06091.1 - 0.0011 18.3 0.0 0.0026 17.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 EEB06091.1 - 0.0025 17.2 0.0 0.0066 15.8 0.0 1.8 1 0 0 1 1 1 1 KaiC DUF2072 PF09845.9 EEB06091.1 - 0.0033 17.7 0.5 0.009 16.3 0.4 1.7 2 0 0 2 2 1 1 Zn-ribbon containing protein AAA_18 PF13238.6 EEB06091.1 - 0.0039 17.7 0.1 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EEB06091.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EEB06091.1 - 0.0045 16.7 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEB06091.1 - 0.0048 16.7 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 EEB06091.1 - 0.0096 15.4 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_13 PF13166.6 EEB06091.1 - 0.0096 14.6 0.4 0.43 9.2 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEB06091.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEB06091.1 - 0.012 14.9 0.1 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EEB06091.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EEB06091.1 - 0.017 15.6 0.1 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EEB06091.1 - 0.018 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EEB06091.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEB06091.1 - 0.024 14.2 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EEB06091.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EEB06091.1 - 0.03 14.7 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 EEB06091.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEB06091.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EEB06091.1 - 0.058 13.0 0.1 0.2 11.3 0.1 1.9 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Parvo_NS1 PF01057.17 EEB06091.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EEB06091.1 - 0.095 12.6 0.0 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain APG6_N PF17675.1 EEB06091.1 - 0.11 13.1 1.1 0.24 11.9 1.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region RILP PF11461.8 EEB06091.1 - 0.12 12.7 1.4 0.28 11.4 1.4 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_11 PF13086.6 EEB06091.1 - 0.14 11.9 0.4 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Blo-t-5 PF11642.8 EEB06091.1 - 0.23 11.4 1.8 5 7.1 1.5 2.4 2 0 0 2 2 2 0 Mite allergen Blo t 5 DivIC PF04977.15 EEB06091.1 - 3.2 7.6 6.1 1.4 8.7 3.7 1.7 2 0 0 2 2 1 0 Septum formation initiator Ribosomal_S13_N PF08069.12 EEB06092.1 - 2e-29 101.4 0.6 4e-29 100.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EEB06092.1 - 2.6e-15 56.4 0.3 3.9e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 SNARE_assoc PF09335.11 EEB06093.1 - 1.1e-10 42.0 4.3 1.1e-10 42.0 4.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein PgaD PF13994.6 EEB06093.1 - 0.022 14.8 0.1 0.045 13.8 0.1 1.6 1 0 0 1 1 1 0 PgaD-like protein PBP_N PF17093.5 EEB06093.1 - 0.14 12.4 1.3 0.54 10.5 0.0 2.4 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus NPL4 PF05021.15 EEB06094.2 - 7.7e-109 363.8 0.0 1.1e-108 363.2 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EEB06094.2 - 5.8e-69 230.8 0.7 1.1e-68 229.9 0.7 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EEB06094.2 - 1.6e-05 25.3 0.0 3.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PX PF00787.24 EEB06095.1 - 2.4e-19 69.4 0.3 6e-19 68.1 0.3 1.7 1 0 0 1 1 1 1 PX domain MutS_II PF05188.17 EEB06095.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 MutS domain II Peptidase_S9 PF00326.21 EEB06096.1 - 3.8e-55 186.6 0.1 7.2e-55 185.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EEB06096.1 - 0.00013 21.7 1.9 0.013 15.2 0.6 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB06096.1 - 0.00088 19.9 0.2 0.0017 19.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EEB06096.1 - 0.001 17.8 0.2 0.051 12.2 0.2 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 EEB06096.1 - 0.0024 16.8 0.4 0.0043 16.0 0.4 1.3 1 0 0 1 1 1 1 Carboxylesterase family Histidinol_dh PF00815.20 EEB06097.1 - 1.1e-152 508.9 0.6 1.2e-152 508.7 0.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase KASH_CCD PF14662.6 EEB06098.1 - 0.0073 16.1 14.2 0.01 15.7 14.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Dynamin_M PF01031.20 EEB06098.1 - 0.0075 15.5 7.3 0.0097 15.2 7.3 1.1 1 0 0 1 1 1 1 Dynamin central region CENP-K PF11802.8 EEB06098.1 - 0.014 15.0 11.2 0.02 14.5 11.2 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Death PF00531.22 EEB06098.1 - 0.025 14.7 6.7 0.09 13.0 5.5 2.5 1 1 1 2 2 2 0 Death domain AAA_13 PF13166.6 EEB06098.1 - 0.037 12.7 10.7 0.042 12.5 10.7 1.1 1 0 0 1 1 1 0 AAA domain Alpha-E PF04168.12 EEB06098.1 - 0.04 13.7 4.3 0.032 14.0 2.5 1.7 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. U1snRNP70_N PF12220.8 EEB06098.1 - 0.049 14.3 1.1 0.049 14.3 1.1 2.8 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal tRNA_NucTran2_2 PF13735.6 EEB06098.1 - 0.29 11.1 9.9 0.5 10.4 9.9 1.5 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF1993 PF09351.10 EEB06098.1 - 0.33 11.1 7.5 0.43 10.7 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Prominin PF05478.11 EEB06098.1 - 0.38 8.6 9.9 0.47 8.4 9.9 1.2 1 0 0 1 1 1 0 Prominin GrpE PF01025.19 EEB06098.1 - 0.44 10.2 10.5 0.64 9.7 10.1 1.4 1 1 0 1 1 1 0 GrpE IFT57 PF10498.9 EEB06098.1 - 0.51 9.2 16.4 0.68 8.8 16.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mcm10 PF09332.11 EEB06098.1 - 0.57 9.6 16.0 0.37 10.2 14.8 1.4 1 1 0 1 1 1 0 Mcm10 replication factor BRE1 PF08647.11 EEB06098.1 - 0.6 10.2 16.6 0.74 9.9 15.5 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EEB06098.1 - 1.8 9.1 15.5 6.7 7.2 15.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 EEB06098.1 - 2.2 7.5 12.7 0.72 9.0 8.8 1.5 1 1 1 2 2 2 0 TMPIT-like protein Sec20 PF03908.13 EEB06098.1 - 2.6 8.0 15.6 0.6 10.1 8.7 2.3 1 1 1 2 2 2 0 Sec20 MAT1 PF06391.13 EEB06098.1 - 2.9 7.7 18.1 1.4 8.7 15.7 1.6 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 ADIP PF11559.8 EEB06098.1 - 3 7.9 24.0 0.2 11.7 18.8 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mobilization_B PF17511.2 EEB06098.1 - 4.3 7.7 13.3 0.67 10.3 5.1 2.4 1 1 1 2 2 2 0 Mobilization protein B MbeB_N PF04837.12 EEB06098.1 - 4.9 7.5 13.5 1.3 9.4 4.5 3.2 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF3456 PF11938.8 EEB06098.1 - 5.3 7.5 9.3 2.5 8.6 6.0 2.0 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP FlaC_arch PF05377.11 EEB06098.1 - 6.4 7.3 11.2 17 5.9 3.3 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FliD_N PF02465.18 EEB06098.1 - 7.7 7.3 17.9 3.3 8.5 1.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3450 PF11932.8 EEB06098.1 - 8.8 5.6 23.8 1.2 8.3 19.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 EEB06098.1 - 9.9 6.6 16.5 18 5.8 16.5 1.5 1 0 0 1 1 1 0 AAA domain DFP PF04127.15 EEB06099.1 - 5.7e-20 71.9 0.0 1.8e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Cmc1 PF08583.10 EEB06100.1 - 1.6e-12 47.2 7.0 2.7e-12 46.5 7.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 EEB06100.1 - 0.0018 18.7 1.9 0.0026 18.1 1.9 1.4 1 1 0 1 1 1 1 GCK domain CHCH PF06747.13 EEB06100.1 - 0.0046 17.1 3.2 0.62 10.3 0.1 2.5 2 0 0 2 2 2 2 CHCH domain Cys_rich_FGFR PF00839.17 EEB06100.1 - 0.0075 16.4 0.3 0.0075 16.4 0.3 1.6 2 0 0 2 2 2 1 Cysteine rich repeat CX9C PF16860.5 EEB06100.1 - 0.0094 15.9 0.5 0.0094 15.9 0.5 1.9 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1987 PF09345.10 EEB06100.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1987) Aminotran_3 PF00202.21 EEB06100.1 - 0.072 11.7 0.2 0.073 11.7 0.2 1.0 1 0 0 1 1 1 0 Aminotransferase class-III DUF3782 PF12644.7 EEB06100.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) Ubiq_cyt_C_chap PF03981.12 EEB06101.1 - 2.7e-33 115.0 0.8 3.7e-33 114.6 0.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.13 EEB06102.1 - 1.1e-51 174.7 0.1 1.4e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family PH PF00169.29 EEB06103.1 - 6.9e-06 26.5 0.0 2.5e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 PH domain PRCC PF10253.9 EEB06104.1 - 2e-14 54.9 15.1 9.6e-14 52.7 15.1 2.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting MatE PF01554.18 EEB06105.1 - 3.5e-58 195.8 30.1 9.9e-31 106.6 10.3 2.5 2 0 0 2 2 2 2 MatE SET PF00856.28 EEB06106.2 - 8.4e-09 36.0 0.3 2.3e-08 34.6 0.0 1.9 2 1 0 2 2 2 1 SET domain HypA PF01155.19 EEB06106.2 - 0.21 11.6 1.4 0.4 10.7 0.3 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4379 PF14311.6 EEB06106.2 - 0.38 11.1 3.4 1.2 9.6 3.4 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain BolA PF01722.18 EEB06107.1 - 4.7e-15 55.6 0.0 1.7e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein DUF3124 PF11322.8 EEB06107.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3124) Ins_P5_2-kin PF06090.12 EEB06108.1 - 1.4e-24 87.2 0.1 1.6e-20 73.9 0.0 2.8 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase Com_YlbF PF06133.11 EEB06108.1 - 0.22 12.1 6.1 0.53 10.9 1.6 3.0 4 0 0 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA V-SNARE_C PF12352.8 EEB06108.1 - 0.23 11.8 1.6 0.77 10.1 0.2 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Exonuc_VII_L PF02601.15 EEB06108.1 - 0.23 11.0 1.3 0.38 10.3 1.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EEB06108.1 - 0.36 11.1 7.2 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein Ribosomal_L12 PF00542.19 EEB06109.1 - 2.9e-21 75.6 16.5 4.2e-21 75.1 5.4 2.8 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EEB06109.1 - 5.2e-14 51.7 3.5 5.4e-14 51.6 0.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain CTK3 PF12243.8 EEB06110.1 - 3.5e-43 146.5 0.0 5.5e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EEB06110.1 - 1.7e-15 56.9 6.8 1.7e-15 56.9 6.8 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus NDUFB11 PF17250.2 EEB06110.1 - 0.038 14.6 0.1 0.088 13.5 0.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Nro1 PF12753.7 EEB06111.1 - 1.2e-19 70.5 3.7 1.1e-18 67.5 0.6 2.3 2 0 0 2 2 2 2 Nuclear pore complex subunit Nro1 REF PF05755.12 EEB06111.1 - 0.34 10.7 5.3 3.6 7.3 0.1 3.2 3 1 0 4 4 4 0 Rubber elongation factor protein (REF) USP8_dimer PF08969.11 EEB06111.1 - 7.9 6.7 6.9 2.1 8.6 0.5 3.0 4 0 0 4 4 4 0 USP8 dimerisation domain CDC73_C PF05179.14 EEB06112.1 - 9.7e-57 191.1 0.0 2.2e-56 189.9 0.0 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EEB06112.1 - 0.014 14.7 0.0 0.047 13.0 0.0 1.7 1 1 1 2 2 2 0 Paf1 complex subunit CDC73 N-terminal Rho_N PF07498.12 EEB06112.1 - 0.15 12.0 0.0 0.88 9.6 0.0 2.0 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain HA2 PF04408.23 EEB06113.1 - 3.1e-21 75.7 0.0 3.1e-21 75.7 0.0 2.6 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEB06113.1 - 4.5e-15 55.8 0.0 1.6e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEB06113.1 - 4e-14 52.9 0.0 9.4e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB06113.1 - 4.7e-07 29.7 0.2 1.3e-06 28.3 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB06113.1 - 1.7e-06 28.4 0.1 3.8e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEB06113.1 - 0.00053 19.8 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEB06113.1 - 0.00063 19.1 0.9 0.00088 18.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EEB06113.1 - 0.00084 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 EEB06113.1 - 0.002 17.8 0.4 0.0058 16.3 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EEB06113.1 - 0.0031 17.9 0.1 0.0073 16.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEB06113.1 - 0.0053 16.8 0.0 2.9 7.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EEB06113.1 - 0.0064 15.6 0.3 0.084 11.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 EEB06113.1 - 0.0098 15.3 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 EEB06113.1 - 0.037 14.5 1.4 0.25 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EEB06113.1 - 0.048 14.2 0.0 0.22 12.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 EEB06113.1 - 0.062 13.0 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 EEB06113.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 EEB06113.1 - 0.17 11.5 0.1 0.55 9.8 0.1 1.9 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EEB06113.1 - 0.18 11.6 0.0 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain WD40 PF00400.32 EEB06114.1 - 7.3e-18 64.6 8.2 4.8e-05 24.1 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06114.1 - 3e-05 24.2 0.1 0.0083 16.4 0.1 3.8 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB06114.1 - 0.0017 17.1 1.3 0.0083 14.8 0.2 2.4 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EEB06114.1 - 0.23 12.0 1.2 7.9 7.1 0.1 3.2 2 1 0 2 2 2 0 PQQ-like domain Y_phosphatase2 PF03162.13 EEB06115.1 - 6.6e-47 159.1 0.0 8.7e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EEB06115.1 - 2.8e-14 53.6 0.0 3.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EEB06115.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB06115.1 - 0.0092 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aim19 PF10315.9 EEB06116.1 - 5.6e-31 107.2 3.0 5.6e-31 107.2 3.0 1.4 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 19 DUF1772 PF08592.11 EEB06116.1 - 0.98 9.7 11.8 0.074 13.4 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DPM2 PF07297.12 EEB06117.1 - 1e-24 86.6 5.8 1.2e-24 86.4 5.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EEB06117.1 - 3.6e-05 23.7 1.3 3.9e-05 23.5 1.3 1.1 1 0 0 1 1 1 1 PIG-P 7TM_GPCR_Str PF10326.9 EEB06117.1 - 0.019 14.3 5.0 0.021 14.2 5.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF3377 PF11857.8 EEB06117.1 - 6.1 6.8 6.7 8.7 6.4 5.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) Homeodomain PF00046.29 EEB06119.1 - 4e-12 45.8 8.5 4.7e-12 45.6 7.1 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EEB06119.1 - 0.032 14.1 1.7 0.044 13.7 0.3 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF4770 PF15994.5 EEB06119.1 - 0.12 12.6 5.6 0.17 12.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF3408 PF11888.8 EEB06119.1 - 3.9 7.6 7.3 7.6 6.7 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TMEM208_SND2 PF05620.11 EEB06119.1 - 7.7 6.3 5.3 16 5.3 5.3 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 tRNA-synt_1g PF09334.11 EEB06121.1 - 7.1e-153 509.0 0.3 9.1e-153 508.6 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEB06121.1 - 4.2e-09 35.2 0.9 0.00013 20.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEB06121.1 - 0.0017 18.3 0.1 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF1977 PF09320.11 EEB06122.1 - 2.4e-25 88.8 1.9 5.5e-25 87.7 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EEB06122.1 - 1.6e-23 82.6 4.2 3.3e-23 81.6 4.2 1.6 1 0 0 1 1 1 1 DnaJ domain DSPc PF00782.20 EEB06123.1 - 1e-33 116.0 0.0 1.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB06123.1 - 9.5e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EEB06123.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pyr_redox_2 PF07992.14 EEB06124.1 - 1.1e-59 202.1 0.1 1.6e-59 201.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EEB06124.1 - 4.6e-31 107.3 0.0 1.7e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EEB06124.1 - 3.7e-19 69.1 2.3 6.1e-16 58.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB06124.1 - 1e-10 41.4 1.8 2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEB06124.1 - 1.1e-06 28.3 0.1 1.4e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EEB06124.1 - 1.8e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EEB06124.1 - 0.0012 18.1 1.5 0.032 13.5 0.9 2.4 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 EEB06124.1 - 0.0013 18.6 0.3 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EEB06124.1 - 0.0018 17.1 2.0 0.017 13.8 0.7 2.8 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EEB06124.1 - 0.0021 17.4 0.2 2.4 7.4 0.3 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EEB06124.1 - 0.0054 15.9 3.3 0.0092 15.1 3.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EEB06124.1 - 0.0093 16.2 6.1 0.0093 16.2 6.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EEB06124.1 - 0.011 14.9 4.8 0.0092 15.1 3.2 1.8 2 1 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EEB06124.1 - 0.011 15.1 2.6 0.056 12.8 0.1 2.6 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EEB06124.1 - 0.031 13.3 0.4 0.055 12.5 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EEB06124.1 - 0.042 13.4 0.1 0.042 13.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EEB06124.1 - 0.073 13.6 0.1 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 EEB06124.1 - 0.21 10.8 1.6 0.64 9.2 0.9 2.0 2 0 0 2 2 2 0 FAD binding domain TatD_DNase PF01026.21 EEB06125.2 - 4.9e-56 189.9 0.0 6.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase HU-HIG PF18291.1 EEB06125.2 - 0.046 13.8 0.1 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif BPL_LplA_LipB PF03099.19 EEB06126.1 - 8.3e-10 38.7 0.2 3.1e-09 36.8 0.2 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C3HC4_2 PF13923.6 EEB06127.1 - 4.7e-10 39.2 10.9 1.1e-09 38.0 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB06127.1 - 3e-09 36.9 5.4 1.3e-08 34.8 5.2 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EEB06127.1 - 4.6e-09 36.5 12.1 6.5e-09 36.0 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EEB06127.1 - 6.2e-09 35.7 6.2 6.6e-09 35.7 4.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEB06127.1 - 7.4e-09 35.3 8.8 1.9e-08 34.0 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEB06127.1 - 2.3e-08 33.8 6.4 4.3e-08 32.9 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB06127.1 - 1.9e-07 30.9 7.7 1.9e-07 30.9 7.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEB06127.1 - 3.1e-07 30.2 6.6 6.3e-07 29.2 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EEB06127.1 - 3.2e-06 27.2 4.7 7.3e-06 26.0 4.7 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EEB06127.1 - 2.5e-05 24.4 12.2 3.4e-05 24.1 10.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain TMCCDC2 PF15844.5 EEB06127.1 - 0.0024 17.8 0.4 0.0036 17.2 0.4 1.3 1 0 0 1 1 1 1 Transmembrane and coiled-coil domain-containing protein 2 zf-RING_6 PF14835.6 EEB06127.1 - 0.011 15.6 2.7 0.023 14.6 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 EEB06127.1 - 0.029 14.5 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-ANAPC11 PF12861.7 EEB06127.1 - 0.079 13.0 3.2 0.17 11.9 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 EEB06127.1 - 0.12 12.4 4.9 0.25 11.4 4.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 EEB06127.1 - 0.27 11.1 7.0 0.69 9.8 7.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EEB06127.1 - 0.78 9.4 7.0 2 8.1 7.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EEB06127.1 - 1.3 9.3 8.3 16 5.8 8.4 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain RINT1_TIP1 PF04437.13 EEB06128.1 - 3.3e-106 356.1 11.0 3.3e-106 356.1 11.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Adaptin_N PF01602.20 EEB06129.1 - 3.9e-106 355.7 15.0 5.8e-106 355.1 15.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EEB06129.1 - 5.7e-32 110.2 0.0 1.2e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EEB06129.1 - 5e-08 33.2 0.1 1.4e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EEB06129.1 - 1.2e-07 31.9 2.2 1.1e-05 25.5 0.0 3.3 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AP4E_app_platf PF14807.6 EEB06129.1 - 0.00029 21.1 0.0 0.00088 19.6 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Coatomer_g_Cpla PF16381.5 EEB06129.1 - 0.0015 18.6 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Anoctamin PF04547.12 EEB06130.2 - 1.7e-93 314.0 13.5 2.1e-93 313.6 13.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_1 PF00076.22 EEB06131.2 - 8.1e-72 237.0 7.5 7.3e-20 70.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB06131.2 - 3.8e-08 33.0 0.0 0.15 11.6 0.0 5.1 4 1 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB06131.2 - 5.4e-05 23.0 0.0 0.16 11.9 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EEB06131.2 - 0.00056 19.9 0.8 55 3.9 0.0 5.4 5 2 1 6 6 6 0 Limkain b1 Nup35_RRM_2 PF14605.6 EEB06131.2 - 0.0012 18.8 0.1 2.5 8.2 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EEB06131.2 - 0.023 14.8 0.0 9.8 6.4 0.0 3.6 4 0 0 4 4 4 0 RNA recognition motif SET_assoc PF11767.8 EEB06131.2 - 0.066 12.9 0.2 36 4.1 0.0 3.9 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Cellulase PF00150.18 EEB06132.1 - 2.9e-14 53.2 3.5 4.2e-14 52.7 3.5 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PseudoU_synth_2 PF00849.22 EEB06133.1 - 3.4e-31 108.5 0.0 5.1e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 EEB06133.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) XPG_N PF00752.17 EEB06134.1 - 6.1e-15 55.5 0.0 1.5e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EEB06134.1 - 5.9e-14 52.2 0.3 4.7e-13 49.3 0.0 2.4 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 EEB06134.1 - 0.00063 20.3 0.0 0.0031 18.1 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EEB06134.1 - 0.0032 18.0 0.0 0.0086 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF155 PF02582.14 EEB06135.1 - 5.4e-52 176.4 0.0 1e-51 175.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 WD40 PF00400.32 EEB06136.1 - 5.5e-37 125.1 18.3 2.7e-06 28.0 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06136.1 - 5.3e-17 61.9 0.5 0.016 15.5 0.1 6.3 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB06136.1 - 8e-07 29.1 0.2 0.052 13.4 0.0 3.6 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EEB06136.1 - 0.00072 18.6 0.1 0.16 10.9 0.0 3.2 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEB06136.1 - 0.0012 17.7 0.1 0.27 9.9 0.0 3.0 3 0 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 EEB06136.1 - 0.015 13.9 0.7 1.1 7.8 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EEB06136.1 - 0.093 12.7 0.7 24 5.0 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PAP_assoc PF03828.19 EEB06137.1 - 6.7e-16 58.2 0.1 2.2e-15 56.6 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEB06137.1 - 2e-13 50.5 0.0 6.5e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEB06137.1 - 1.1e-05 25.4 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Nuc_sug_transp PF04142.15 EEB06138.2 - 1.3e-11 44.2 1.7 1.9e-11 43.7 1.7 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EEB06138.2 - 2.1e-07 31.2 19.8 4.5e-05 23.6 9.3 3.1 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EEB06138.2 - 5.7e-07 29.2 6.1 7.7e-07 28.7 6.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 EEB06138.2 - 1.1e-05 25.1 7.5 1.5e-05 24.7 7.5 1.2 1 0 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 EEB06138.2 - 0.00018 20.9 8.8 0.00034 19.9 7.2 1.8 1 1 0 2 2 2 1 UAA transporter family CRT-like PF08627.10 EEB06138.2 - 0.0014 17.6 9.9 0.0027 16.7 9.9 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 EEB06138.2 - 0.014 15.5 3.9 0.027 14.5 3.9 1.7 1 1 0 1 1 1 0 Putative transmembrane family 234 DUF423 PF04241.15 EEB06138.2 - 0.12 12.6 1.6 0.29 11.4 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF373 PF04123.13 EEB06138.2 - 1.4 8.3 10.1 0.32 10.4 5.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Peptidase_M50B PF13398.6 EEB06138.2 - 3.6 7.2 15.1 33 4.0 15.9 2.1 1 1 1 2 2 2 0 Peptidase M50B-like DUF2530 PF10745.9 EEB06138.2 - 4 7.7 6.7 0.25 11.6 0.8 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) CHD5 PF04420.14 EEB06139.1 - 1.7e-42 145.0 2.2 1.9e-42 144.8 2.2 1.0 1 0 0 1 1 1 1 CHD5-like protein T3SS_basalb_I PF17001.5 EEB06139.1 - 0.15 12.7 0.3 0.23 12.1 0.3 1.2 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI Peptidase_M41 PF01434.18 EEB06140.1 - 5.6e-61 205.7 0.2 9e-61 205.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEB06140.1 - 5e-42 143.5 0.0 1.2e-40 139.0 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 EEB06140.1 - 2.4e-12 47.2 0.1 6e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 EEB06140.1 - 2.4e-10 40.0 0.1 6.2e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EEB06140.1 - 0.00024 21.1 0.0 0.0019 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB06140.1 - 0.00076 19.9 0.6 0.05 14.0 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 EEB06140.1 - 0.0052 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EEB06140.1 - 0.0061 16.7 0.0 0.049 13.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEB06140.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB06140.1 - 0.013 15.8 0.3 0.68 10.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EEB06140.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB06140.1 - 0.16 11.3 0.2 0.44 9.9 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Scs3p PF10261.9 EEB06141.1 - 6.9e-52 176.4 26.1 8.7e-42 143.3 8.7 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Pkinase PF00069.25 EEB06142.2 - 2.3e-62 210.7 0.0 3.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06142.2 - 1.3e-36 126.3 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06142.2 - 9.4e-07 28.4 0.0 4.3e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEB06142.2 - 2.8e-05 23.1 0.0 4.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEB06142.2 - 0.04 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4712 PF15830.5 EEB06142.2 - 0.051 13.3 0.1 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4712) FTA2 PF13095.6 EEB06142.2 - 0.066 12.8 0.0 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB06142.2 - 0.1 12.5 0.1 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEB06142.2 - 0.2 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.29 EEB06143.1 - 5.9e-41 140.1 0.1 1.5e-40 138.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB06143.1 - 3.4e-29 101.4 0.1 9.3e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB06143.1 - 2.3e-06 27.7 0.1 1.9e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEB06143.1 - 0.1 12.9 0.3 0.4 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.21 EEB06144.1 - 2.2e-77 261.0 12.9 1.1e-41 143.3 4.4 2.0 1 1 1 2 2 2 2 HCO3- transporter family DUF2070 PF09843.9 EEB06144.1 - 1.3 7.2 9.0 2.5 6.3 9.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NPR3 PF03666.13 EEB06145.1 - 3.5e-113 378.9 10.5 2.4e-93 313.5 8.2 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Nic96 PF04097.14 EEB06146.1 - 1.6e-164 548.8 0.0 2.1e-164 548.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ANAPC3 PF12895.7 EEB06146.1 - 0.0016 18.6 1.8 2.3 8.5 0.0 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Flg_bb_rod PF00460.20 EEB06146.1 - 0.18 11.8 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Flagella basal body rod protein HSP70 PF00012.20 EEB06147.1 - 4e-262 870.8 4.3 4.5e-262 870.6 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB06147.1 - 8.6e-16 57.7 0.1 1.5e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EEB06147.1 - 0.00038 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EEB06147.1 - 0.031 13.6 0.6 0.067 12.4 0.2 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HGTP_anticodon PF03129.20 EEB06147.1 - 0.043 14.0 0.3 0.13 12.4 0.3 1.8 1 0 0 1 1 1 0 Anticodon binding domain Cnd1_N PF12922.7 EEB06147.1 - 0.36 10.7 2.5 0.6 9.9 2.5 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term TarH PF02203.15 EEB06147.1 - 1.7 8.5 3.8 3.1 7.7 3.8 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Phage_Mu_F PF04233.14 EEB06147.1 - 7.7 7.3 6.1 45 4.8 2.5 2.9 2 1 1 3 3 3 0 Phage Mu protein F like protein Metallophos PF00149.28 EEB06148.1 - 2.5e-36 126.1 0.0 3.1e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEB06148.1 - 0.018 15.5 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EEB06148.1 - 0.02 14.6 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain LRR_4 PF12799.7 EEB06149.1 - 1.9e-25 88.5 41.1 3.7e-05 24.0 1.2 8.9 6 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEB06149.1 - 1.4e-21 76.0 39.1 1.4e-07 31.2 1.7 7.8 4 3 5 10 10 10 7 Leucine rich repeat LRR_9 PF14580.6 EEB06149.1 - 2.5e-08 33.6 14.4 0.0017 17.9 2.8 4.2 2 1 1 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 EEB06149.1 - 0.011 16.1 36.6 1.1 10.0 0.7 10.3 9 4 2 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 EEB06149.1 - 0.04 14.0 26.2 1.2 9.3 0.1 7.6 9 0 0 9 9 9 0 Leucine Rich repeat SUR7 PF06687.12 EEB06150.1 - 1e-15 57.9 18.7 1.7e-15 57.2 18.7 1.3 1 0 0 1 1 1 1 SUR7/PalI family ELO PF01151.18 EEB06150.1 - 0.012 15.1 2.1 0.017 14.7 2.1 1.2 1 0 0 1 1 1 0 GNS1/SUR4 family COX6A PF02046.15 EEB06151.2 - 1.7e-30 105.8 0.1 1.9e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Sas10_Utp3 PF04000.15 EEB06152.1 - 2.9e-16 59.8 1.3 2.9e-16 59.8 1.3 1.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Mis14 PF08641.12 EEB06152.1 - 0.0041 17.4 3.5 0.75 10.1 0.4 2.1 2 0 0 2 2 2 2 Kinetochore protein Mis14 like HXXSHH PF07586.11 EEB06152.1 - 0.21 11.1 2.0 0.25 10.9 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) BLOC1_2 PF10046.9 EEB06152.1 - 0.21 11.9 3.5 0.42 11.0 0.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 EEB06152.1 - 0.32 11.6 4.9 2.2 8.9 1.0 2.3 2 0 0 2 2 2 0 SlyX XhlA PF10779.9 EEB06152.1 - 0.84 9.9 4.4 9.9 6.5 0.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA TP_methylase PF00590.20 EEB06153.2 - 1e-49 169.3 0.1 2.4e-49 168.2 0.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EEB06153.2 - 1.3e-06 28.8 0.0 5.5e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EEB06153.2 - 0.00067 19.2 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EEB06153.2 - 0.0098 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SET PF00856.28 EEB06154.1 - 6.9e-15 55.8 0.0 1.1e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 SET domain DASH_Spc19 PF08287.11 EEB06155.1 - 2.4e-26 92.5 13.7 1.4e-25 90.0 13.7 1.8 1 1 0 1 1 1 1 Spc19 AAA_13 PF13166.6 EEB06155.1 - 0.0016 17.2 0.2 0.0016 17.2 0.2 1.0 1 0 0 1 1 1 1 AAA domain COG6 PF06419.11 EEB06155.1 - 0.0082 14.4 8.4 0.18 10.0 2.5 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 DASH_Dad2 PF08654.10 EEB06155.1 - 0.025 15.0 1.2 0.63 10.5 0.0 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 BLOC1_2 PF10046.9 EEB06155.1 - 0.031 14.6 2.7 1.1 9.6 0.0 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 EEB06155.1 - 0.08 13.3 3.5 0.21 12.0 0.6 2.8 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_L37e PF01907.19 EEB06156.1 - 2.5e-27 94.8 11.3 4.3e-27 94.0 11.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EEB06156.1 - 0.0066 16.4 1.4 0.01 15.8 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 EEB06156.1 - 0.075 13.1 0.9 0.1 12.6 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EEB06156.1 - 0.086 12.3 3.1 0.22 11.0 3.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_10 PF16685.5 EEB06156.1 - 0.087 13.0 2.0 0.11 12.6 2.0 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF2688 PF10892.8 EEB06156.1 - 2.4 7.7 6.4 12 5.5 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Kelch_3 PF13415.6 EEB06157.1 - 1.7e-34 117.5 4.5 7.3e-07 29.3 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EEB06157.1 - 3e-33 113.6 6.0 2.1e-08 34.0 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EEB06157.1 - 8.7e-33 111.7 0.3 6.7e-09 35.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EEB06157.1 - 2e-32 110.6 2.5 9.7e-06 25.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EEB06157.1 - 7.9e-32 108.5 1.9 9.5e-07 28.9 0.1 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EEB06157.1 - 2.7e-26 90.5 0.7 2.2e-05 24.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif tRNA-synt_2 PF00152.20 EEB06158.1 - 9.2e-80 268.0 0.0 1.5e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEB06158.1 - 5.9e-05 23.0 0.7 0.0001 22.2 0.7 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEB06158.1 - 0.014 14.8 0.8 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Nop53 PF07767.11 EEB06158.1 - 0.59 9.5 14.1 30 3.9 14.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Peptidase_S49_N PF08496.10 EEB06158.1 - 0.97 9.5 4.8 2.1 8.4 4.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FSH1 PF03959.13 EEB06159.1 - 1.9e-62 210.7 0.0 2.5e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DHFR_1 PF00186.19 EEB06159.1 - 1.7e-27 96.1 0.0 2e-26 92.6 0.0 2.2 1 1 0 1 1 1 1 Dihydrofolate reductase Abhydrolase_2 PF02230.16 EEB06159.1 - 0.039 13.8 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EEB06159.1 - 0.054 12.7 0.0 0.97 8.6 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEB06159.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AhpC-TSA PF00578.21 EEB06160.1 - 8.6e-38 129.1 0.0 1.1e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEB06160.1 - 2e-18 66.5 0.0 2.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EEB06160.1 - 3.8e-08 33.0 0.0 8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EEB06160.1 - 0.036 14.0 0.0 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC Slu7 PF11708.8 EEB06161.1 - 1.7e-40 139.5 20.6 1e-39 136.9 20.7 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EEB06161.1 - 0.024 14.3 0.4 0.06 13.1 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EEB06161.1 - 0.052 13.6 2.1 0.088 12.9 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4050 PF13259.6 EEB06161.1 - 7.2 6.9 12.3 1.2 9.5 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) RRM_1 PF00076.22 EEB06162.1 - 1.3e-12 47.4 0.0 1.3e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L21e PF01157.18 EEB06163.1 - 7e-46 154.2 6.7 1.1e-45 153.6 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e CSN8_PSD8_EIF3K PF10075.9 EEB06164.1 - 1.4e-19 70.5 0.2 2.2e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HAT_KAT11 PF08214.11 EEB06165.1 - 3.4e-63 214.1 0.8 4e-63 213.8 0.8 1.1 1 0 0 1 1 1 1 Histone acetylation protein Toxin_18 PF08087.11 EEB06165.1 - 0.026 14.5 1.2 0.046 13.7 1.2 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily Tudor_3 PF18115.1 EEB06166.1 - 1.3e-17 63.4 0.1 3.4e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 EEB06166.1 - 9.5e-15 54.7 0.1 3.1e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEB06166.1 - 1.6e-09 38.0 0.0 4.9e-07 30.1 0.0 3.1 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rad9_Rad53_bind PF08605.10 EEB06166.1 - 4.4e-06 26.9 0.1 8.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Cg6151-P PF10233.9 EEB06167.2 - 3.9e-34 117.4 12.0 4.7e-34 117.1 12.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P AgrB PF04647.15 EEB06167.2 - 0.034 13.5 9.0 0.047 13.0 9.0 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Cytochrom_B558a PF05038.13 EEB06167.2 - 0.067 12.8 6.3 0.45 10.1 6.3 1.9 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit TMEM72 PF16054.5 EEB06167.2 - 0.073 12.8 5.1 0.087 12.5 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 PRA1 PF03208.19 EEB06167.2 - 3.1 7.4 14.6 0.04 13.6 5.1 2.0 1 1 1 2 2 2 0 PRA1 family protein Tfb5 PF06331.12 EEB06168.1 - 7.5e-24 83.5 0.1 8.2e-24 83.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ThiS PF02597.20 EEB06168.1 - 0.11 13.2 0.1 0.13 12.9 0.1 1.2 1 0 0 1 1 1 0 ThiS family PGM_PMM_I PF02878.16 EEB06170.1 - 1.5e-37 128.4 0.2 2.2e-37 127.8 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EEB06170.1 - 9.9e-21 74.1 0.0 1.8e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EEB06170.1 - 2.1e-14 54.0 0.0 4.9e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EEB06170.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DASH_Duo1 PF08651.10 EEB06172.1 - 2.4e-24 84.9 2.3 3.7e-24 84.3 2.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 RR_TM4-6 PF06459.12 EEB06172.1 - 0.1 12.4 9.0 0.14 11.9 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.18 EEB06172.1 - 0.83 8.0 3.9 1.6 7.1 3.9 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF1682 PF07946.14 EEB06172.1 - 1.1 8.4 14.3 1.5 7.9 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDRGK PF09756.9 EEB06172.1 - 1.5 8.4 18.3 2.4 7.7 18.3 1.2 1 0 0 1 1 1 0 DDRGK domain DASH_Dad2 PF08654.10 EEB06172.1 - 3 8.3 13.2 23 5.5 13.2 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad2 AAA_13 PF13166.6 EEB06172.1 - 4.3 5.8 12.6 5.5 5.5 12.6 1.1 1 0 0 1 1 1 0 AAA domain RINGv PF12906.7 EEB06173.2 - 0.00065 19.8 3.0 0.00065 19.8 3.0 2.2 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.8 EEB06173.2 - 0.46 10.7 3.3 1.7 8.9 1.8 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EEB06173.2 - 1.2 9.5 9.0 0.07 13.5 2.8 2.2 2 1 0 2 2 2 0 Ring finger domain Cyclin_N PF00134.23 EEB06174.1 - 4.7e-19 68.4 0.7 1.1e-18 67.2 0.7 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EEB06174.1 - 0.00019 21.4 0.1 0.00044 20.2 0.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EEB06174.1 - 0.0012 19.0 1.0 0.77 9.9 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain SAM_LFY PF01698.16 EEB06174.1 - 0.1 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain Isy1 PF06246.12 EEB06175.1 - 1.7e-61 208.0 7.0 6.1e-61 206.2 7.0 1.7 1 1 0 1 1 1 1 Isy1-like splicing family NICE-3 PF07406.11 EEB06175.1 - 0.0043 17.0 1.1 0.66 9.9 0.1 2.1 1 1 1 2 2 2 2 NICE-3 protein Tubulin PF00091.25 EEB06176.1 - 2.4e-67 227.0 0.0 4.1e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEB06176.1 - 1.4e-45 154.5 0.1 7.5e-45 152.2 0.1 2.1 3 0 0 3 3 3 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EEB06176.1 - 5.5e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EEB06176.1 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GSHPx PF00255.19 EEB06177.2 - 2.9e-46 155.5 0.1 4.2e-46 155.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EEB06177.2 - 0.00013 21.8 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEB06177.2 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin Gemin7 PF11095.8 EEB06178.1 - 3e-17 62.3 0.1 3.6e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) WD40 PF00400.32 EEB06179.1 - 1.5e-25 88.9 15.0 1.1e-05 26.0 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06179.1 - 3.5e-15 56.1 0.3 0.00023 21.4 0.0 4.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB06179.1 - 4.8e-07 29.8 0.0 0.00069 19.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EEB06179.1 - 0.00033 20.1 0.2 0.49 9.7 0.1 3.0 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EEB06179.1 - 0.0014 17.4 0.1 2.2 6.8 0.0 3.0 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 EEB06179.1 - 0.065 13.2 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EEB06179.1 - 0.073 11.6 0.2 0.87 8.1 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain WD40_like PF17005.5 EEB06179.1 - 0.2 10.9 0.0 7 5.9 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain Exo_endo_phos PF03372.23 EEB06180.1 - 2.9e-16 59.7 0.3 3.6e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3099 PF11298.8 EEB06180.1 - 0.26 11.5 4.8 0.62 10.2 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Memo PF01875.17 EEB06181.1 - 4.2e-81 272.1 0.0 4.8e-81 271.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.18 EEB06181.1 - 0.0092 15.1 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase YqaH PF17448.2 EEB06181.1 - 0.067 13.5 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized YqaH-like UvrD-helicase PF00580.21 EEB06182.2 - 9.1e-62 209.4 0.0 2.2e-61 208.1 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EEB06182.2 - 1.8e-60 205.2 1.4 6e-60 203.5 0.3 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EEB06182.2 - 3.5e-32 111.7 0.2 1.1e-31 110.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EEB06182.2 - 8.5e-12 44.7 0.0 2.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EEB06182.2 - 1.9e-08 34.3 0.0 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EEB06182.2 - 5.8e-06 26.2 0.2 0.0048 16.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EEB06182.2 - 0.00048 19.8 0.1 0.07 12.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EEB06182.2 - 0.01 15.6 0.1 0.01 15.6 0.1 2.9 3 1 0 3 3 3 0 AAA domain Helicase_RecD PF05127.14 EEB06182.2 - 0.037 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Helicase Terminase_6 PF03237.15 EEB06182.2 - 0.094 12.4 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Terminase-like family RRM_1 PF00076.22 EEB06183.1 - 9.7e-87 284.8 3.4 5.3e-22 77.4 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EEB06183.1 - 4.3e-24 84.5 1.9 1.1e-23 83.1 0.3 2.5 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EEB06183.1 - 2e-11 43.6 0.1 0.024 14.2 0.0 4.3 1 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB06183.1 - 1.2e-05 25.1 0.0 0.0043 16.9 0.0 3.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EEB06183.1 - 7.7e-05 22.7 0.6 8 6.7 0.0 5.0 4 3 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EEB06183.1 - 0.00021 21.2 1.2 6.5 6.8 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EEB06183.1 - 0.0034 17.4 11.0 2.4 8.3 0.5 5.0 5 0 0 5 5 5 2 RNA binding motif DUF4523 PF15023.6 EEB06183.1 - 0.019 14.8 0.0 26 4.6 0.0 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF4523) Nefa_Nip30_N PF10187.9 EEB06183.1 - 0.029 14.7 0.2 0.029 14.7 0.2 3.4 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 OB_RNB PF08206.11 EEB06183.1 - 0.11 12.1 2.1 28 4.5 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 EEB06183.1 - 0.15 12.6 7.4 2.8 8.5 0.6 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT MMgT PF10270.9 EEB06184.1 - 1.2e-16 60.8 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter DASH_Dam1 PF08653.10 EEB06185.1 - 5.8e-20 70.8 2.4 5.9e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 DASH complex subunit Dam1 FTA4 PF13093.6 EEB06185.1 - 0.00094 19.1 0.3 0.0014 18.6 0.3 1.2 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spectrin PF00435.21 EEB06185.1 - 0.0014 19.1 1.0 0.0084 16.6 0.0 2.0 2 0 0 2 2 2 1 Spectrin repeat MukB PF04310.12 EEB06185.1 - 0.012 15.5 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 MukB N-terminal ZapB PF06005.12 EEB06185.1 - 0.012 16.0 5.7 0.15 12.5 5.7 2.1 1 1 0 1 1 1 0 Cell division protein ZapB AKNA PF12443.8 EEB06185.1 - 0.03 15.0 0.3 0.03 15.0 0.3 1.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor HBM PF16591.5 EEB06185.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain ZnuA PF01297.17 EEB06185.1 - 0.066 12.6 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic CRAL_TRIO PF00650.20 EEB06186.1 - 9.1e-35 119.7 0.1 1.5e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EEB06186.1 - 3.6e-07 30.4 0.2 6.7e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEB06186.1 - 0.016 15.4 0.1 0.059 13.6 0.1 2.1 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain EutQ PF06249.12 EEB06186.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ubiquitin PF00240.23 EEB06187.1 - 7.4e-34 115.3 0.6 7.4e-34 115.3 0.6 1.8 2 1 1 3 3 3 1 Ubiquitin family Ribosomal_S27 PF01599.19 EEB06187.1 - 2.5e-25 88.3 2.5 2.5e-25 88.3 2.5 1.8 2 0 0 2 2 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EEB06187.1 - 4.6e-16 58.4 0.7 4.6e-16 58.4 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB06187.1 - 8.5e-06 26.1 0.5 0.00012 22.5 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB06187.1 - 0.00046 20.3 0.5 0.001 19.1 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EEB06187.1 - 0.0036 17.6 0.5 0.0071 16.7 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB06187.1 - 0.0052 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EEB06187.1 - 0.0093 16.5 0.7 0.013 16.0 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EEB06187.1 - 0.016 15.2 1.0 5.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Zn_Tnp_IS1595 PF12760.7 EEB06187.1 - 0.036 14.0 1.5 0.06 13.3 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 EEB06187.1 - 0.038 14.0 0.5 0.11 12.6 0.5 1.6 1 1 1 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 EEB06187.1 - 0.045 13.7 2.0 0.11 12.5 1.3 2.0 1 1 1 2 2 2 0 Nudix N-terminal DUF4925 PF16272.5 EEB06187.1 - 0.057 12.9 0.1 0.078 12.5 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) OrfB_Zn_ribbon PF07282.11 EEB06187.1 - 0.13 12.2 1.0 0.29 11.1 1.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 EEB06187.1 - 0.27 11.2 2.7 0.91 9.5 2.7 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 EEB06187.1 - 0.32 10.8 3.8 1.3 8.8 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EEB06187.1 - 1.2 8.6 4.7 0.31 10.5 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain RF-1 PF00472.20 EEB06188.1 - 7e-15 55.0 0.2 9.7e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 RF-1 domain YqbF PF14553.6 EEB06188.1 - 0.053 13.4 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Frag1 PF10277.9 EEB06189.1 - 5.5e-36 124.2 5.3 1.3e-35 122.9 10.0 3.9 3 2 0 3 3 3 2 Frag1/DRAM/Sfk1 family Mis14 PF08641.12 EEB06190.2 - 6.1e-16 58.9 0.5 6.1e-16 58.9 0.5 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like VPS13_C PF16909.5 EEB06191.1 - 9.8e-66 220.9 5.6 4.8e-63 212.1 1.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EEB06191.1 - 9.4e-63 212.1 0.7 3.9e-61 206.8 0.0 3.7 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EEB06191.1 - 1.2e-61 208.6 0.9 1.2e-61 208.6 0.9 3.6 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EEB06191.1 - 1.3e-60 204.7 8.8 3.8e-59 200.0 1.7 3.6 4 0 0 4 4 4 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 EEB06191.1 - 3.1e-37 127.2 0.7 1.4e-36 125.1 0.7 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EEB06191.1 - 0.00014 22.1 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain bPH_3 PF14470.6 EEB06191.1 - 0.16 12.3 1.2 0.65 10.4 1.2 2.1 1 0 0 1 1 1 0 Bacterial PH domain Sds3 PF08598.11 EEB06192.1 - 4e-13 49.9 3.0 4e-13 49.9 3.0 2.3 2 0 0 2 2 2 1 Sds3-like O-antigen_lig PF13425.6 EEB06192.1 - 0.26 10.0 2.0 0.42 9.4 2.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HIT PF01230.23 EEB06193.1 - 4e-24 85.2 0.0 5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EEB06193.1 - 2e-12 47.6 0.0 2.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EEB06193.1 - 0.00074 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 G-patch PF01585.23 EEB06194.1 - 9.2e-14 51.1 2.7 9.2e-14 51.1 2.7 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EEB06194.1 - 0.0091 16.1 0.4 0.0091 16.1 0.4 2.9 2 1 0 2 2 2 1 G-patch domain Mucin PF01456.17 EEB06194.1 - 0.018 15.0 1.0 0.018 15.0 1.0 3.1 3 1 0 3 3 3 0 Mucin-like glycoprotein RR_TM4-6 PF06459.12 EEB06194.1 - 4.6 7.0 11.8 9.5 6.0 11.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDP-OH_P_transf PF01066.21 EEB06195.2 - 6.2e-12 46.1 0.2 6.2e-12 46.1 0.2 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 EEB06196.1 - 5.8e-38 130.1 0.0 7.3e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 EEB06197.1 - 2.7e-35 122.0 0.0 4.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEB06197.1 - 2.1e-21 75.8 0.1 5.6e-21 74.5 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EEB06197.1 - 2.4e-17 62.7 0.0 4.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 EEB06197.1 - 2.1e-12 46.9 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Vac14_Fig4_bd PF11916.8 EEB06198.1 - 5.6e-56 189.0 6.3 3.4e-48 163.6 5.2 2.6 1 1 1 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EEB06198.1 - 9.6e-40 135.1 0.8 6.9e-36 122.7 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EEB06198.1 - 3.6e-09 36.1 1.0 0.011 16.0 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EEB06198.1 - 2.3e-05 24.7 0.2 6 7.3 0.0 4.5 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EEB06198.1 - 0.00017 22.0 2.4 1 10.0 0.0 4.5 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 EEB06198.1 - 0.00095 19.2 3.7 6.2 6.8 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EEB06198.1 - 0.02 14.4 1.2 6.2 6.3 0.0 4.0 3 1 1 4 4 4 0 Tti2 family Proteasom_PSMB PF10508.9 EEB06198.1 - 0.039 12.5 1.4 0.33 9.4 0.2 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit WD40_3 PF15911.5 EEB06198.1 - 0.061 13.3 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF5071 PF16804.5 EEB06198.1 - 0.098 12.9 0.0 1.7 8.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) AMMECR1 PF01871.17 EEB06199.1 - 1.2e-44 151.8 0.0 1.4e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 PP-binding PF00550.25 EEB06200.1 - 8.9e-13 48.4 0.1 1.1e-12 48.2 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EEB06200.1 - 0.00019 21.6 0.3 0.00027 21.1 0.3 1.3 1 1 0 1 1 1 1 Acyl-carrier Rhodanese PF00581.20 EEB06201.2 - 4.3e-16 59.3 0.0 5.7e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain ArsA_ATPase PF02374.15 EEB06202.1 - 2.3e-113 378.4 0.2 2.6e-113 378.2 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EEB06202.1 - 6.7e-16 58.7 0.0 3.8e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EEB06202.1 - 4.4e-12 46.2 0.0 6.3e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EEB06202.1 - 1.8e-06 27.7 0.1 0.00068 19.3 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 EEB06202.1 - 6.6e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EEB06202.1 - 0.00018 21.1 0.0 0.0005 19.6 0.0 1.7 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EEB06202.1 - 0.00025 20.6 6.6 0.00063 19.3 2.3 3.1 2 2 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase NB-ARC PF00931.22 EEB06202.1 - 0.013 14.7 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EEB06202.1 - 0.02 14.5 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EEB06202.1 - 0.029 13.8 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 EEB06202.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.11 EEB06202.1 - 0.11 11.8 1.0 7.2 5.8 0.1 2.4 3 0 0 3 3 3 0 VirC1 protein PhoD PF09423.10 EEB06203.2 - 4.5e-14 52.2 1.4 9.4e-11 41.3 0.0 2.3 1 1 0 2 2 2 2 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EEB06203.2 - 0.0092 16.5 0.1 0.028 15.0 0.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EEB06203.2 - 0.0099 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Snf7 PF03357.21 EEB06204.1 - 2.5e-48 163.9 17.8 3.9e-48 163.3 17.8 1.2 1 0 0 1 1 1 1 Snf7 USP8_interact PF08941.10 EEB06204.1 - 0.69 9.7 4.5 0.19 11.5 0.6 1.9 1 1 1 2 2 2 0 USP8 interacting Fe_hyd_lg_C PF02906.14 EEB06204.1 - 2 8.0 5.3 1.8 8.2 4.3 1.3 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SMAP PF15477.6 EEB06204.1 - 2.7 9.0 6.4 0.24 12.4 0.8 2.2 2 1 0 2 2 2 0 Small acidic protein family Forkhead PF00250.18 EEB06205.2 - 3.6e-31 107.3 0.2 8.2e-31 106.1 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EEB06205.2 - 6.3e-15 55.3 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EEB06205.2 - 0.019 15.2 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 FHA domain cNMP_binding PF00027.29 EEB06206.1 - 2.6e-40 136.4 0.1 3.3e-20 71.9 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EEB06206.1 - 1.8e-05 24.3 0.9 5.2e-05 22.8 0.9 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Pro_isomerase PF00160.21 EEB06207.1 - 1.2e-48 165.4 0.1 1.4e-48 165.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyr_Deacylase PF02580.16 EEB06209.2 - 6.2e-57 192.2 0.7 6.9e-57 192.0 0.7 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF1958 PF09211.10 EEB06209.2 - 0.0059 16.9 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1958) Fzo_mitofusin PF04799.13 EEB06209.2 - 0.037 13.6 0.6 0.062 12.8 0.2 1.6 1 1 1 2 2 2 0 fzo-like conserved region PPR_2 PF13041.6 EEB06210.1 - 6.1e-10 39.1 1.2 0.012 15.8 0.0 5.6 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 EEB06210.1 - 1.7e-07 31.0 0.6 15 6.1 0.0 5.9 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 EEB06210.1 - 0.0018 18.3 0.0 1 9.5 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EEB06210.1 - 0.049 13.0 0.2 3.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP rRNA_processing PF08524.11 EEB06211.1 - 1.6e-16 60.7 41.0 1.9e-14 53.9 41.0 2.2 1 1 0 1 1 1 1 rRNA processing ArfGap PF01412.18 EEB06211.1 - 0.63 10.1 7.0 1 9.4 7.0 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Presenilin PF01080.17 EEB06211.1 - 4.5 5.9 10.8 5.2 5.7 10.8 1.0 1 0 0 1 1 1 0 Presenilin Autophagy_act_C PF03987.15 EEB06212.1 - 2.1e-13 50.7 1.3 4.7e-13 49.5 1.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Mago-bind PF09282.10 EEB06213.1 - 3e-15 55.7 0.6 6.4e-15 54.7 0.6 1.6 1 0 0 1 1 1 1 Mago binding zf-UBR PF02207.20 EEB06214.1 - 4.9e-18 65.1 13.6 4.9e-18 65.1 13.6 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EEB06214.1 - 0.00021 21.0 0.1 0.00059 19.6 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS LRR_8 PF13855.6 EEB06215.1 - 1.5e-49 165.6 48.2 3.2e-09 36.4 0.9 9.0 5 3 2 8 8 8 8 Leucine rich repeat Guanylate_cyc PF00211.20 EEB06215.1 - 7.1e-38 130.1 0.0 1.5e-37 129.0 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 EEB06215.1 - 1.6e-32 111.0 71.3 1.3e-05 25.4 1.3 12.6 7 3 9 16 16 16 14 Leucine Rich repeats (2 copies) PP2C PF00481.21 EEB06215.1 - 3.5e-27 95.7 0.0 5.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 EEB06215.1 - 3e-07 30.1 22.1 0.23 11.0 0.2 6.0 3 2 2 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 EEB06215.1 - 4.3e-07 29.6 56.7 20 6.2 0.1 17.6 15 3 0 15 15 15 2 Leucine Rich Repeat LRR_6 PF13516.6 EEB06215.1 - 4.8e-05 23.1 43.4 0.74 10.0 0.1 13.2 13 0 0 13 13 13 2 Leucine Rich repeat RA PF00788.23 EEB06215.1 - 0.015 15.9 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF2406 PF10295.9 EEB06216.1 - 1.4e-15 57.7 0.1 3.1e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Vesiculo_matrix PF06326.12 EEB06216.1 - 0.012 15.4 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein RCR PF12273.8 EEB06217.1 - 7.2e-10 39.6 4.0 1.5e-09 38.5 4.0 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4668 PF15701.5 EEB06217.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF4064 PF13273.6 EEB06217.1 - 0.054 13.8 0.0 0.064 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF5453 PF17534.2 EEB06217.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF2561 PF10812.8 EEB06217.1 - 0.098 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CYYR1 PF10873.8 EEB06217.1 - 0.89 10.0 11.1 1.8 9.0 11.1 1.6 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ProRS-C_1 PF09180.11 EEB06218.1 - 6.5e-25 87.1 0.6 1.4e-24 86.1 0.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EEB06218.1 - 5.3e-19 68.2 0.0 1.2e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEB06218.1 - 1.6e-16 60.8 0.0 4e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EEB06218.1 - 5e-16 58.9 0.6 9.4e-16 58.0 0.6 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA_int_endo PF01974.17 EEB06219.1 - 3.2e-14 52.7 0.0 1.1e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF1682 PF07946.14 EEB06219.1 - 3.1 6.9 5.0 4.6 6.4 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LCM PF04072.14 EEB06220.2 - 2.6e-23 82.9 0.0 4.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EEB06220.2 - 1.8e-09 37.5 0.2 7e-06 26.0 0.0 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EEB06220.2 - 5.6e-05 23.3 2.3 0.37 11.1 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EEB06220.2 - 0.0017 18.5 0.7 0.59 10.5 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 EEB06220.2 - 0.0033 17.4 4.0 3.5 7.7 0.0 5.4 6 0 0 6 6 6 1 Kelch motif UvdE PF03851.14 EEB06221.2 - 1.2e-106 356.0 0.0 1.4e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE Serglycin PF04360.12 EEB06222.1 - 0.004 17.1 0.2 0.0096 15.9 0.2 1.6 1 0 0 1 1 1 1 Serglycin KilA-N PF04383.13 EEB06222.1 - 0.025 14.4 0.0 2.6 7.9 0.0 2.5 1 1 0 1 1 1 0 KilA-N domain CDK5_activator PF03261.15 EEB06222.1 - 0.53 9.8 8.0 0.96 8.9 8.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PPP4R2 PF09184.11 EEB06222.1 - 3.9 7.0 24.2 1.1 8.8 20.5 1.8 1 1 1 2 2 2 0 PPP4R2 Glyco_transf_15 PF01793.16 EEB06223.1 - 1.2e-117 392.8 10.9 1.5e-117 392.5 10.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF866 PF05907.13 EEB06224.1 - 8.9e-55 184.9 0.2 9.9e-55 184.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Basic PF01586.16 EEB06224.1 - 0.0043 18.2 0.3 0.0092 17.1 0.3 1.6 1 0 0 1 1 1 1 Myogenic Basic domain Herpes_UL55 PF04537.12 EEB06224.1 - 0.014 15.4 0.3 0.022 14.8 0.3 1.4 1 1 0 1 1 1 0 Herpesvirus UL55 protein DUF3716 PF12511.8 EEB06224.1 - 0.034 14.2 4.7 0.05 13.7 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Mcm10 PF09332.11 EEB06224.1 - 0.17 11.3 1.6 0.24 10.8 1.6 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Rubredoxin_2 PF18073.1 EEB06224.1 - 3.1 7.6 13.0 1.3 8.8 0.6 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain ORC6 PF05460.13 EEB06225.1 - 3.3e-19 69.4 3.3 5e-16 58.9 0.9 2.1 1 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Serglycin PF04360.12 EEB06225.1 - 0.0086 16.0 0.1 0.47 10.4 0.0 2.2 2 0 0 2 2 2 1 Serglycin DASH_Duo1 PF08651.10 EEB06225.1 - 0.039 13.7 0.9 0.088 12.6 0.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Actin PF00022.19 EEB06226.1 - 1.4e-82 277.5 0.0 3.3e-80 269.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEB06226.1 - 0.002 17.0 0.0 0.63 8.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsJ PF01728.19 EEB06227.1 - 1.9e-68 230.1 0.0 2.2e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EEB06227.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PTPA PF03095.15 EEB06228.1 - 1.9e-111 372.3 0.0 2.2e-111 372.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein BPL_LplA_LipB PF03099.19 EEB06229.2 - 2.2e-13 50.2 0.1 3.6e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BUD22 PF09073.10 EEB06230.1 - 7.2e-62 210.1 30.2 7.2e-62 210.1 30.2 2.0 1 1 1 2 2 2 1 BUD22 TPR_MLP1_2 PF07926.12 EEB06231.1 - 0.097 12.7 27.1 0.041 13.9 13.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EHN PF06441.12 EEB06231.1 - 0.1 13.0 5.4 1.7 9.1 0.6 2.6 2 1 0 2 2 2 0 Epoxide hydrolase N terminus HMMR_N PF15905.5 EEB06231.1 - 0.15 11.5 27.6 0.084 12.3 24.2 2.2 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 EEB06231.1 - 0.91 9.6 12.7 0.84 9.7 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 EEB06231.1 - 1.3 9.7 26.5 1 10.0 2.8 3.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RPW8 PF05659.11 EEB06231.1 - 1.7 8.3 10.0 0.19 11.4 0.5 2.6 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2203 PF09969.9 EEB06231.1 - 1.9 9.2 13.3 1.4e+03 -0.0 13.3 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ERM PF00769.19 EEB06231.1 - 2 8.1 28.6 0.28 11.0 13.0 2.8 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Med9 PF07544.13 EEB06231.1 - 3 8.0 14.6 0.74 9.9 1.0 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 EEB06231.1 - 3.3 8.2 12.7 2.5 8.6 2.1 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CALCOCO1 PF07888.11 EEB06231.1 - 4.2 6.1 25.1 0.32 9.8 11.1 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG13 PF10033.9 EEB06232.1 - 1.1e-58 198.8 0.1 1.7e-58 198.2 0.1 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 CBF PF03914.17 EEB06233.1 - 9.6e-51 172.2 9.3 1.3e-50 171.7 0.1 3.2 3 0 0 3 3 3 2 CBF/Mak21 family Adaptin_N PF01602.20 EEB06233.1 - 0.36 9.3 5.6 2 6.9 3.5 2.6 2 2 0 2 2 2 0 Adaptin N terminal region Anp1 PF03452.14 EEB06234.1 - 5.5e-102 340.7 0.0 6.7e-102 340.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EEB06234.1 - 0.002 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF658 PF04936.12 EEB06234.1 - 0.11 12.3 0.7 0.19 11.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DUF1510 PF07423.11 EEB06234.1 - 0.12 12.5 0.4 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) Septin PF00735.18 EEB06235.1 - 4.7e-102 341.0 0.2 4.7e-102 341.0 0.2 1.6 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EEB06235.1 - 0.00019 21.4 0.1 0.021 14.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EEB06235.1 - 0.00059 20.4 0.3 0.012 16.1 0.0 2.8 2 1 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 EEB06235.1 - 0.0044 16.8 0.2 0.061 13.1 0.0 2.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EEB06235.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EEB06235.1 - 0.014 14.6 0.1 0.18 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EEB06235.1 - 0.015 15.6 0.0 0.063 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EEB06235.1 - 0.033 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.6 EEB06235.1 - 0.034 13.0 8.4 3.7 6.2 6.4 2.5 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EEB06235.1 - 0.042 14.1 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EEB06235.1 - 0.072 13.4 0.3 0.24 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EEB06235.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Exonuc_VII_L PF02601.15 EEB06235.1 - 1.3 8.5 5.4 2.1 7.8 5.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 EEB06235.1 - 1.5 8.9 4.7 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain CENP-L PF13092.6 EEB06236.1 - 1.2e-16 61.4 0.5 2.3e-16 60.5 0.5 1.5 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 GYF PF02213.16 EEB06237.1 - 6.9e-20 70.5 0.5 1.3e-19 69.5 0.5 1.5 1 0 0 1 1 1 1 GYF domain zf-C2H2_jaz PF12171.8 EEB06238.1 - 5.4e-09 36.1 5.6 9.8e-09 35.3 5.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEB06238.1 - 0.028 14.8 4.6 0.047 14.0 4.5 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 EEB06238.1 - 0.087 12.6 2.5 0.13 12.0 2.5 1.3 1 0 0 1 1 1 0 zinc-finger C2H2-type JAB PF01398.21 EEB06239.2 - 4.3e-18 65.4 0.0 9.1e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EEB06239.2 - 1.2e-07 31.5 0.6 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 EEB06239.2 - 6.4e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain DUF4518 PF15008.6 EEB06239.2 - 0.0057 15.9 0.1 0.0086 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) DUF745 PF05335.13 EEB06239.2 - 0.22 11.2 0.1 0.35 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SRP14 PF02290.15 EEB06240.1 - 4.9e-12 46.1 0.0 4.9e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Peptidase_C54 PF03416.19 EEB06241.1 - 1.7e-61 208.0 0.3 3.6e-61 207.0 0.3 1.4 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 EEB06241.1 - 0.043 13.3 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C78 zf-C2H2_2 PF12756.7 EEB06242.1 - 1.6e-22 79.7 13.0 1.1e-20 73.8 2.7 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) Rhomboid PF01694.22 EEB06243.1 - 1.7e-06 28.1 10.7 1.7e-06 28.1 10.7 2.0 1 1 1 2 2 2 1 Rhomboid family Keratin_assoc PF09775.9 EEB06243.1 - 0.51 10.0 12.8 0.016 14.9 6.5 1.7 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 NIF PF03031.18 EEB06244.2 - 1.2e-24 86.8 0.0 2.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EEB06244.2 - 1.4e-05 24.9 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl PF00364.22 EEB06244.2 - 0.0069 16.2 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEB06244.2 - 0.058 13.2 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like BRCT PF00533.26 EEB06244.2 - 0.14 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S30 PF04758.14 EEB06245.1 - 7.4e-29 99.7 5.0 8e-29 99.6 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Glucan_synthase PF02364.15 EEB06246.2 - 0 1272.7 0.0 0 1271.9 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEB06246.2 - 1.9e-37 128.5 3.4 6.3e-37 126.8 3.4 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 XhlA PF10779.9 EEB06246.2 - 2.2 8.6 4.2 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Glyco_hydro_72 PF03198.14 EEB06247.1 - 1.1e-132 442.0 6.5 1.7e-132 441.4 6.5 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EEB06247.1 - 7e-20 71.5 4.5 2.5e-19 69.7 4.5 2.1 1 0 0 1 1 1 1 X8 domain TPR_2 PF07719.17 EEB06248.1 - 3.8e-11 42.2 0.2 0.0032 17.4 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEB06248.1 - 5e-10 39.0 0.5 0.00054 20.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06248.1 - 1.7e-09 37.7 1.4 0.052 14.4 0.0 6.3 6 2 1 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06248.1 - 2.1e-08 33.7 0.2 0.00062 19.8 0.0 5.1 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06248.1 - 6e-06 26.7 0.1 0.15 12.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06248.1 - 7.1e-06 25.6 0.7 0.39 10.6 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB06248.1 - 3.5e-05 23.9 0.7 0.001 19.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EEB06248.1 - 0.00086 19.0 0.9 1.3 8.7 0.1 3.1 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_15 PF13429.6 EEB06248.1 - 0.004 16.4 0.5 2.4 7.3 0.0 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06248.1 - 0.0055 17.0 1.4 14 6.0 0.0 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEB06248.1 - 0.028 14.8 0.1 0.27 11.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06248.1 - 0.054 14.2 0.0 4 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06248.1 - 0.12 12.4 0.2 16 5.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 EEB06249.1 - 5e-19 68.3 0.0 7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EEB06249.1 - 0.00074 19.9 0.2 0.0023 18.3 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EEB06249.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EEB06249.1 - 0.013 15.9 0.1 0.015 15.7 0.1 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EEB06249.1 - 0.12 12.2 0.1 1.2 8.9 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain zf-H2C2_5 PF13909.6 EEB06249.1 - 0.18 11.6 1.7 0.42 10.4 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-HIT PF04438.16 EEB06250.2 - 2.2e-08 33.8 14.1 3.2e-08 33.3 14.1 1.3 1 0 0 1 1 1 1 HIT zinc finger GlnE PF03710.15 EEB06250.2 - 0.036 13.5 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase Alpha-amylase_C PF02806.18 EEB06250.2 - 0.13 12.8 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain WD40 PF00400.32 EEB06251.1 - 0.00014 22.6 2.8 0.01 16.7 0.3 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat CactinC_cactus PF09732.9 EEB06252.2 - 3.2e-52 175.7 3.2 5.4e-52 175.0 3.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EEB06252.2 - 3.7e-32 111.7 2.3 3.7e-32 111.7 2.3 2.0 2 1 0 2 2 2 1 Conserved mid region of cactin SF3A2 PF16835.5 EEB06252.2 - 1.2e-05 25.5 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) EAP30 PF04157.16 EEB06252.2 - 4.3 6.6 7.0 9.3 5.5 1.6 2.5 3 0 0 3 3 3 0 EAP30/Vps36 family Ribosomal_S19e PF01090.19 EEB06253.1 - 4.4e-60 201.3 0.1 4.9e-60 201.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Kinesin PF00225.23 EEB06254.1 - 1.6e-119 398.7 0.0 2.5e-119 398.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEB06254.1 - 6.1e-26 91.1 0.0 1.4e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding GPS2_interact PF15784.5 EEB06254.1 - 0.0025 18.2 2.0 0.0034 17.8 0.1 2.2 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Bac_DnaA PF00308.18 EEB06254.1 - 0.073 12.9 2.0 8.5 6.1 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein CorA PF01544.18 EEB06254.1 - 0.99 8.7 7.9 5.2 6.3 1.0 2.9 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein ABATE PF07336.11 EEB06254.1 - 2.2 9.0 6.7 4.5 8.0 0.9 3.4 3 1 0 3 3 3 0 Putative stress-induced transcription regulator IMPDH PF00478.25 EEB06255.1 - 2.8e-134 447.5 2.5 3.2e-134 447.3 2.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EEB06255.1 - 3e-15 56.4 1.0 8.2e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 EEB06255.1 - 2.1e-09 36.9 0.4 7.8e-09 35.0 0.8 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EEB06255.1 - 1.7e-06 27.7 6.3 0.00033 20.1 5.0 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EEB06255.1 - 0.00074 19.0 1.9 0.0053 16.2 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EEB06255.1 - 0.0053 16.1 3.8 0.022 14.1 0.6 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 EEB06255.1 - 0.051 13.0 0.6 0.13 11.6 0.2 1.8 1 1 0 1 1 1 0 KDPG and KHG aldolase Dus PF01207.17 EEB06255.1 - 0.053 12.6 2.7 0.56 9.2 0.1 2.2 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 EEB06255.1 - 0.093 11.8 7.0 0.084 12.0 4.4 1.9 1 1 1 2 2 2 0 Conserved region in glutamate synthase DHHC PF01529.20 EEB06256.1 - 5.9e-31 107.3 14.9 5.9e-31 107.3 14.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase MerC PF03203.14 EEB06256.1 - 3.8 8.0 13.2 2.2 8.7 3.6 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein PTPLA PF04387.14 EEB06257.1 - 3.1e-54 183.1 10.6 3.1e-54 183.1 10.6 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA LSM PF01423.22 EEB06258.2 - 1.1e-17 63.4 0.1 1.5e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain CTU2 PF10288.9 EEB06259.1 - 3.1e-13 49.9 1.7 3.1e-13 49.9 1.7 2.3 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 EEB06259.1 - 1e-05 25.4 0.0 0.0018 18.0 0.0 2.3 1 1 0 1 1 1 1 PP-loop family L51_S25_CI-B8 PF05047.16 EEB06260.2 - 4.1e-07 29.8 0.1 7.6e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain UPF0300 PF08594.10 EEB06262.1 - 3.4e-05 23.3 0.4 5.2e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) DUF2014 PF09427.10 EEB06263.2 - 1.1e-46 159.3 0.1 1.8e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EEB06263.2 - 4.4e-18 65.0 0.3 8.3e-18 64.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_4 PF07721.14 EEB06263.2 - 0.025 15.2 0.4 0.025 15.2 0.4 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PRP38 PF03371.15 EEB06264.1 - 5.9e-59 198.8 0.1 6.9e-59 198.6 0.1 1.0 1 0 0 1 1 1 1 PRP38 family VPS9 PF02204.18 EEB06265.1 - 1.9e-09 37.7 0.0 4.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 EEB06265.1 - 4.2e-08 33.7 0.4 0.001 19.6 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB06265.1 - 1.1e-05 25.5 0.6 0.00038 20.7 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEB06265.1 - 0.00026 21.5 2.0 0.095 13.3 0.4 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEB06265.1 - 0.012 16.1 1.2 4.1 8.3 0.1 5.1 6 0 0 6 6 6 0 Ankyrin repeat PX PF00787.24 EEB06265.1 - 0.025 14.6 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 PX domain F_bP_aldolase PF01116.20 EEB06266.1 - 6.3e-90 301.4 0.0 7.1e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pkinase PF00069.25 EEB06267.1 - 4e-50 170.6 0.1 2.2e-42 145.3 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06267.1 - 1.3e-25 90.2 0.0 5e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06267.1 - 7.4e-07 28.8 0.0 5.5e-06 25.9 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EEB06267.1 - 0.00011 21.4 0.1 0.00017 20.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EEB06267.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEB06267.1 - 0.00021 20.7 0.1 0.00034 20.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEB06267.1 - 0.00078 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EEB06267.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UCH PF00443.29 EEB06268.2 - 2e-32 112.7 0.7 3.4e-32 111.9 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB06268.2 - 2.4e-08 34.0 6.6 4.6e-07 29.7 6.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1016_N PF17761.1 EEB06268.2 - 0.00071 19.8 0.3 0.043 14.0 0.1 2.2 2 0 0 2 2 2 1 DUF1016 N-terminal domain DNA_RNApol_7kD PF03604.13 EEB06269.1 - 1e-16 60.3 4.8 1.3e-16 60.0 4.8 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.18 EEB06269.1 - 0.00037 20.3 0.8 0.53 10.2 0.0 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) DUF35_N PF12172.8 EEB06269.1 - 0.003 17.4 0.4 0.84 9.6 0.1 2.3 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ISL3 PF14690.6 EEB06269.1 - 0.011 16.4 1.4 0.022 15.4 0.2 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.7 EEB06269.1 - 0.012 15.6 0.5 0.017 15.2 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EEB06269.1 - 0.014 15.5 1.8 0.028 14.5 1.8 1.6 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 EEB06269.1 - 0.018 15.0 0.3 0.021 14.9 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NinF PF05810.12 EEB06269.1 - 0.023 14.5 0.6 0.03 14.2 0.6 1.2 1 0 0 1 1 1 0 NinF protein zinc-ribbon_6 PF10005.9 EEB06269.1 - 0.024 15.3 0.5 0.03 15.0 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 EEB06269.1 - 0.037 13.7 0.1 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_2 PF13240.6 EEB06269.1 - 0.04 13.7 0.8 0.1 12.3 0.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC PF07967.13 EEB06269.1 - 0.055 13.5 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like OrfB_Zn_ribbon PF07282.11 EEB06269.1 - 0.06 13.3 1.1 0.086 12.8 1.1 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3268 PF11672.8 EEB06269.1 - 0.076 13.4 1.8 0.52 10.7 1.8 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain Rubredoxin_2 PF18073.1 EEB06269.1 - 0.089 12.5 3.5 6.8 6.5 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_Tnp_IS1595 PF12760.7 EEB06269.1 - 0.17 11.9 3.1 0.49 10.4 0.5 1.9 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 EEB06269.1 - 0.25 11.0 2.4 3.3 7.4 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_recom PF13408.6 EEB06269.1 - 1.4 9.5 8.1 1.2 9.7 2.0 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DNA_methylase PF00145.17 EEB06270.1 - 2.2e-42 145.6 0.0 1.1e-41 143.3 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Met_10 PF02475.16 EEB06270.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein JmjC PF02373.22 EEB06270.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase OB_NTP_bind PF07717.16 EEB06271.2 - 4.3e-21 75.1 0.0 1.2e-20 73.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEB06271.2 - 1.7e-18 66.8 0.0 1.7e-18 66.8 0.0 3.1 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEB06271.2 - 7.9e-16 58.4 0.0 2.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB06271.2 - 1e-07 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB06271.2 - 7.7e-06 26.2 0.0 5.2e-05 23.5 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB06271.2 - 3.3e-05 24.3 0.2 0.00017 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEB06271.2 - 0.00015 21.6 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEB06271.2 - 0.004 17.2 0.4 2.4 8.1 0.2 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SRP54 PF00448.22 EEB06271.2 - 0.013 15.1 0.0 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EEB06271.2 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EEB06271.2 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain PWI PF01480.17 EEB06271.2 - 0.11 12.8 0.0 0.39 11.1 0.0 2.0 1 0 0 1 1 1 0 PWI domain ORF_2_N PF18492.1 EEB06271.2 - 0.15 12.3 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain SpoVAC_SpoVAEB PF03862.13 EEB06271.2 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein NuiA PF07924.11 EEB06272.1 - 3.4e-05 24.2 0.2 0.0043 17.4 0.0 2.3 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein DUF5334 PF17268.2 EEB06272.1 - 0.084 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5334) LsmAD PF06741.13 EEB06273.2 - 4.5e-29 100.8 0.6 4.5e-29 100.8 0.6 2.7 3 0 0 3 3 3 1 LsmAD domain DUF202 PF02656.15 EEB06274.1 - 3.8e-14 52.9 2.6 3.8e-14 52.9 2.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) WD40 PF00400.32 EEB06275.1 - 7.5e-44 146.8 11.8 4.2e-12 46.4 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06275.1 - 4.7e-13 49.2 1.1 0.0028 17.9 0.0 5.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB06275.1 - 3.3e-10 39.4 0.1 0.0024 16.9 0.0 3.9 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EEB06275.1 - 0.00019 20.5 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EEB06275.1 - 0.00024 19.9 6.7 0.28 9.8 0.1 4.6 1 1 2 5 5 5 3 Nucleoporin Nup120/160 Hira PF07569.11 EEB06275.1 - 0.00056 19.7 0.5 4.5 6.9 0.0 3.7 1 1 3 4 4 4 2 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 EEB06275.1 - 0.0086 14.6 0.0 0.76 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EEB06275.1 - 0.013 14.3 0.2 4.9 5.8 0.0 3.2 1 1 1 3 3 3 0 Nup133 N terminal like Frtz PF11768.8 EEB06275.1 - 0.018 13.3 0.0 0.81 7.9 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Methyltransf_23 PF13489.6 EEB06276.1 - 0.00016 21.5 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB06276.1 - 0.0051 17.5 0.0 0.84 10.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB06276.1 - 0.0067 17.1 0.0 0.054 14.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB06276.1 - 0.14 12.8 0.0 1.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Reprolysin_5 PF13688.6 EEB06277.1 - 2.3e-27 96.4 0.0 2.3e-27 96.4 0.0 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EEB06277.1 - 6.8e-20 71.6 0.0 1.9e-17 63.6 0.0 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EEB06277.1 - 2.6e-18 66.6 33.9 2.6e-18 66.6 33.9 3.9 3 1 0 3 3 3 1 Disintegrin Reprolysin_2 PF13574.6 EEB06277.1 - 2.2e-17 63.6 0.1 3e-16 59.9 0.1 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EEB06277.1 - 1.5e-08 34.8 0.6 1.5e-08 34.8 0.6 2.7 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 EEB06277.1 - 7.3e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EEB06277.1 - 0.0014 18.5 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EEB06277.1 - 0.035 13.3 0.1 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Ribosomal_L3 PF00297.22 EEB06278.1 - 9.8e-194 643.4 7.0 1.1e-193 643.2 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NUC173 PF08161.12 EEB06279.1 - 6.7e-66 221.8 3.6 1.6e-63 214.0 0.0 4.3 3 1 2 5 5 5 2 NUC173 domain HEAT_2 PF13646.6 EEB06279.1 - 0.0039 17.6 1.2 8.7 6.8 0.0 5.3 6 0 0 6 6 6 1 HEAT repeats Ipi1_N PF12333.8 EEB06279.1 - 9.9 6.8 11.8 32 5.2 0.6 5.9 4 2 2 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation PX PF00787.24 EEB06281.1 - 8.4e-17 61.2 0.4 1.5e-16 60.3 0.4 1.5 1 0 0 1 1 1 1 PX domain DUF3050 PF11251.8 EEB06281.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) SCIMP PF15050.6 EEB06281.1 - 0.14 12.6 0.2 0.86 10.1 0.0 2.1 2 0 0 2 2 2 0 SCIMP protein DUF16 PF01519.16 EEB06281.1 - 0.38 11.3 4.1 16 6.0 3.7 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 PHD PF00628.29 EEB06282.1 - 1.1e-11 44.5 5.3 1.1e-11 44.5 5.3 2.0 2 0 0 2 2 2 1 PHD-finger Uds1 PF15456.6 EEB06282.1 - 0.049 13.8 12.3 0.04 14.1 1.9 2.6 3 0 0 3 3 3 0 Up-regulated During Septation ABC_tran_CTD PF16326.5 EEB06282.1 - 0.61 10.4 9.6 0.085 13.1 3.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF1295 PF06966.12 EEB06283.1 - 1.9e-49 168.3 10.3 2.4e-49 168.0 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Wzy_C_2 PF11846.8 EEB06283.1 - 0.029 14.3 0.6 0.029 14.3 0.6 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal NAF PF03822.14 EEB06283.1 - 0.049 13.8 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 NAF domain CRPA PF05745.11 EEB06283.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) ICMT PF04140.14 EEB06283.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.6 4 0 0 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2070 PF09843.9 EEB06283.1 - 6.1 5.0 10.2 2.5 6.3 6.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) LSM PF01423.22 EEB06284.1 - 1.9e-19 69.1 0.8 2.1e-19 68.9 0.8 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB06284.1 - 0.014 15.5 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RTP1_C1 PF10363.9 EEB06285.2 - 1.4e-25 89.7 0.2 1.4e-25 89.7 0.2 3.4 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EEB06285.2 - 4.1e-09 36.7 0.9 0.0034 17.8 0.8 4.1 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EEB06285.2 - 0.0017 18.4 1.0 1.2 9.6 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EEB06285.2 - 0.0031 17.6 2.9 0.074 13.1 0.0 3.9 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EEB06285.2 - 0.0062 16.2 3.9 3.1 7.3 0.3 3.6 3 1 1 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C2 PF10304.9 EEB06285.2 - 0.04 13.6 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 VASt PF16016.5 EEB06286.1 - 2.9e-37 128.5 1.7 1.5e-36 126.2 0.3 2.3 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EEB06286.1 - 8.8e-28 96.5 0.1 1.6e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 GRAM domain HORMA PF02301.18 EEB06287.1 - 1.9e-25 89.8 0.2 2.4e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EEB06287.1 - 0.00068 19.7 0.5 0.0044 17.0 0.5 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 VWA_3 PF13768.6 EEB06287.1 - 0.011 15.6 0.1 0.093 12.7 0.1 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Ribosomal_S30AE PF02482.19 EEB06287.1 - 0.042 14.6 0.3 0.071 13.9 0.3 1.3 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF244 PF03112.14 EEB06287.1 - 0.057 13.3 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF NRDE-2 PF08424.10 EEB06288.1 - 1e-76 258.2 1.0 1e-76 258.2 1.0 2.2 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 EEB06288.1 - 0.00016 21.8 1.1 1.7 9.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Nse4_C PF08743.10 EEB06289.1 - 1.9e-29 101.7 0.1 5.5e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EEB06289.1 - 0.00011 22.2 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE APG12 PF04110.13 EEB06289.1 - 0.3 11.5 2.0 0.57 10.6 0.1 2.2 2 1 1 3 3 3 0 Ubiquitin-like autophagy protein Apg12 IFRD PF05004.13 EEB06290.1 - 2.9e-33 115.3 12.1 3.9e-33 114.9 12.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EEB06290.1 - 0.038 14.4 0.0 0.18 12.2 0.0 2.2 1 1 0 1 1 1 0 HEAT repeats LAGLIDADG_3 PF14528.6 EEB06290.1 - 0.1 12.9 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 LAGLIDADG-like domain Hom_end PF05204.14 EEB06290.1 - 0.8 9.9 0.0 0.8 9.9 0.0 2.5 3 0 0 3 3 3 0 Homing endonuclease DUF1741 PF08427.10 EEB06291.1 - 5.8e-18 65.4 4.0 2e-17 63.7 3.3 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) MFS_1 PF07690.16 EEB06292.2 - 9.5e-33 113.6 49.5 1.7e-31 109.5 44.4 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB06292.2 - 3.8e-15 55.3 15.7 6.8e-15 54.5 15.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB06292.2 - 3.2e-13 49.4 11.0 3.2e-13 49.4 11.0 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter CSTF_C PF14304.6 EEB06292.2 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Phage_holin_2_2 PF10746.9 EEB06292.2 - 0.16 11.6 0.8 0.42 10.3 0.8 1.7 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II LTV PF04180.14 EEB06294.2 - 2.6e-98 330.3 18.9 3e-98 330.1 18.9 1.0 1 0 0 1 1 1 1 Low temperature viability protein EF-hand_14 PF17959.1 EEB06294.2 - 0.087 13.2 2.2 0.26 11.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain MMR_HSR1 PF01926.23 EEB06295.2 - 3.7e-17 62.5 0.0 2.2e-14 53.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB06295.2 - 5.7e-09 35.7 0.0 7.9e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEB06295.2 - 1.8e-06 28.0 0.1 0.0045 16.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EEB06295.2 - 0.0014 18.7 1.4 0.22 11.5 0.4 2.8 2 1 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EEB06295.2 - 0.043 13.1 1.4 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RseA_C PF03873.13 EEB06296.1 - 0.067 13.4 1.2 3.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Spo12 PF05032.12 EEB06297.1 - 2.3e-16 59.4 1.9 2.3e-16 59.4 1.9 2.4 2 1 1 3 3 3 1 Spo12 family UBA PF00627.31 EEB06298.1 - 2.2e-06 27.5 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EEB06298.1 - 0.0083 15.9 0.3 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain HLH PF00010.26 EEB06299.1 - 2.6e-12 46.5 1.6 5.8e-12 45.4 1.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 EEB06299.1 - 0.00043 20.4 2.5 0.00068 19.7 2.5 1.3 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term APG6_N PF17675.1 EEB06299.1 - 0.024 15.2 6.1 0.034 14.7 6.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region SET PF00856.28 EEB06299.1 - 0.056 13.8 0.2 0.071 13.5 0.2 1.2 1 0 0 1 1 1 0 SET domain V_ATPase_I PF01496.19 EEB06299.1 - 0.58 8.0 4.8 0.67 7.8 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM171 PF15471.6 EEB06299.1 - 2.6 7.0 4.7 0.82 8.6 1.5 1.7 1 1 0 1 1 1 0 Transmembrane protein family 171 LMBR1 PF04791.16 EEB06299.1 - 3.1 6.6 3.5 3.4 6.5 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC_membrane PF00664.23 EEB06300.1 - 1.4e-94 316.9 32.1 6.5e-52 176.9 7.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEB06300.1 - 1.2e-50 171.6 0.2 7.6e-30 104.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EEB06300.1 - 1.8e-11 43.9 0.0 0.0022 17.5 0.0 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEB06300.1 - 7.4e-07 29.3 0.2 0.031 14.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB06300.1 - 2.2e-06 27.7 0.0 0.0091 15.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEB06300.1 - 2e-05 24.2 0.3 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EEB06300.1 - 3.6e-05 23.7 1.4 0.98 9.2 0.1 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEB06300.1 - 4.3e-05 24.1 1.3 0.2 12.1 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EEB06300.1 - 0.00049 19.9 0.6 1.3 8.7 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEB06300.1 - 0.0008 19.8 1.0 1.6 9.1 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 EEB06300.1 - 0.004 16.9 0.2 4.1 7.1 0.0 3.5 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 EEB06300.1 - 0.0044 17.3 0.4 2.6 8.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EEB06300.1 - 0.0064 16.6 1.0 0.23 11.5 0.0 2.8 3 0 0 3 3 2 1 Dynamin family NB-ARC PF00931.22 EEB06300.1 - 0.0097 15.1 0.9 3.2 6.9 0.0 3.1 3 1 0 3 3 3 1 NB-ARC domain DUF87 PF01935.17 EEB06300.1 - 0.01 15.9 0.3 0.21 11.7 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EEB06300.1 - 0.025 14.6 0.1 19 5.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EEB06300.1 - 0.027 14.2 5.3 1.2 8.8 0.1 2.6 3 0 0 3 3 2 0 AAA ATPase domain T2SSE PF00437.20 EEB06300.1 - 0.073 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EEB06300.1 - 0.089 13.2 0.1 5.6 7.4 0.1 2.8 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 EEB06300.1 - 0.11 12.1 0.2 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.9 EEB06300.1 - 0.12 11.2 0.5 5.4 5.7 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 EEB06300.1 - 0.12 11.7 0.2 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EEB06300.1 - 0.13 11.7 0.1 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEB06300.1 - 0.16 11.6 0.0 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEB06300.1 - 0.31 11.0 1.1 6.1 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain STE3 PF02076.15 EEB06301.1 - 5.3e-60 203.1 20.2 6.8e-60 202.7 20.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor His_biosynth PF00977.21 EEB06302.2 - 1.4e-32 113.1 0.1 1.5e-31 109.7 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein Orbi_NS1 PF01718.16 EEB06302.2 - 0.032 12.7 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Aldolase PF01081.19 EEB06302.2 - 0.18 11.2 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4602 PF15375.6 EEB06303.1 - 3.7e-10 40.2 11.3 6.5e-10 39.4 11.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) DUF722 PF05263.11 EEB06303.1 - 0.062 13.5 0.3 0.089 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) RNR_inhib PF08591.10 EEB06304.1 - 8.7e-05 23.8 0.0 0.00012 23.3 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Erf4 PF10256.9 EEB06305.1 - 3e-28 98.3 0.0 3.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Rit1_C PF17184.4 EEB06306.1 - 8.7e-98 327.1 0.0 1.2e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EEB06306.1 - 7e-17 61.7 0.1 1.7e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain DBD_HTH PF18430.1 EEB06306.1 - 1.5 8.7 4.5 1.3 8.8 0.3 2.9 3 0 0 3 3 3 0 Putative DNA-binding domain T5orf172 PF10544.9 EEB06307.1 - 3.9e-13 49.8 0.4 7.9e-13 48.8 0.4 1.5 1 0 0 1 1 1 1 T5orf172 domain MF_alpha PF04648.12 EEB06307.1 - 0.085 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Yeast mating factor alpha hormone zf-Paramyx-P PF13008.7 EEB06307.1 - 0.1 12.1 3.0 0.72 9.4 0.0 3.2 4 0 0 4 4 4 0 Zinc-binding domain of Paramyxoviridae V protein GSH_synth_ATP PF03917.17 EEB06308.2 - 2.9e-127 424.5 0.5 3.4e-127 424.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EEB06308.2 - 5.9e-30 103.8 0.3 3.9e-29 101.1 0.3 2.4 3 0 0 3 3 3 1 Eukaryotic glutathione synthase Pro-kuma_activ PF09286.11 EEB06308.2 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain HGTP_anticodon PF03129.20 EEB06309.1 - 5.1e-23 81.0 0.0 1.4e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEB06309.1 - 2e-06 27.9 0.0 4.3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Gas_vesicle_C PF01304.17 EEB06309.1 - 0.44 10.6 2.0 0.99 9.5 2.0 1.6 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain TrkH PF02386.16 EEB06310.1 - 2.6e-161 537.5 13.4 1.2e-156 522.1 13.1 2.0 2 0 0 2 2 2 2 Cation transport protein PGA2 PF07543.12 EEB06310.1 - 0.033 14.2 2.3 9.9 6.1 2.6 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 MCM PF00493.23 EEB06311.1 - 1.4e-105 351.4 0.3 4.7e-105 349.6 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EEB06311.1 - 5.9e-36 123.1 0.0 7.5e-35 119.5 0.0 2.3 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EEB06311.1 - 1.3e-29 102.5 2.7 3.6e-29 101.0 2.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEB06311.1 - 2.1e-17 63.6 0.1 6.1e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEB06311.1 - 2.8e-05 23.6 0.0 0.001 18.5 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEB06311.1 - 5.6e-05 23.2 0.0 0.00028 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEB06311.1 - 0.00032 20.6 0.1 0.0019 18.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB06311.1 - 0.062 13.0 0.1 0.88 9.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EEB06311.1 - 0.095 12.4 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 AAA domain TTC5_OB PF16669.5 EEB06311.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain COX5A PF02284.16 EEB06312.2 - 1.6e-33 114.7 0.0 2.2e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 EEB06313.2 - 8.6e-47 159.8 17.0 9.8e-47 159.6 17.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mito_carr PF00153.27 EEB06314.1 - 4e-10 39.5 6.6 0.011 15.6 0.0 4.6 4 2 0 4 4 4 4 Mitochondrial carrier protein FAM176 PF14851.6 EEB06314.1 - 0.013 15.2 3.2 0.021 14.5 3.2 1.2 1 0 0 1 1 1 0 FAM176 family DDRGK PF09756.9 EEB06314.1 - 0.14 11.7 5.5 0.22 11.1 5.5 1.2 1 0 0 1 1 1 0 DDRGK domain Dynactin_p62 PF05502.13 EEB06314.1 - 0.32 9.7 2.8 0.45 9.2 2.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family MRNIP PF15749.5 EEB06314.1 - 0.38 11.5 4.2 0.56 10.9 4.2 1.2 1 0 0 1 1 1 0 MRN-interacting protein DNA_pol_phi PF04931.13 EEB06314.1 - 9.6 4.2 10.3 14 3.7 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CRM1_C PF08767.11 EEB06315.1 - 1.4e-132 441.7 2.2 1.4e-132 441.7 2.2 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EEB06315.1 - 1.2e-41 142.3 15.1 5.3e-40 136.9 6.9 5.0 4 1 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EEB06315.1 - 3.6e-34 116.2 3.9 1.2e-33 114.6 3.9 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EEB06315.1 - 3.7e-30 103.8 3.5 6.1e-30 103.1 1.3 2.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EEB06315.1 - 7.4e-20 70.2 0.6 2.2e-19 68.6 0.6 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EEB06315.1 - 2.6e-15 56.1 2.4 5.7e-15 55.0 0.3 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF502 PF04367.13 EEB06315.1 - 0.094 12.6 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF502) Sid-5 PF17204.3 EEB06315.1 - 0.098 12.8 2.5 1.6 8.9 0.3 3.4 3 0 0 3 3 3 0 Sid-5 family PNP_UDP_1 PF01048.20 EEB06316.1 - 2.9e-45 154.4 0.2 3.6e-45 154.1 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HECT PF00632.25 EEB06317.1 - 7e-89 298.3 0.0 1.3e-88 297.4 0.0 1.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EEB06317.1 - 3.6e-11 43.0 7.7 7.5e-09 35.5 0.4 2.9 2 0 0 2 2 2 2 WW domain C2 PF00168.30 EEB06317.1 - 3.2e-05 24.2 0.0 7.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Stk19 PF10494.9 EEB06317.1 - 0.039 13.7 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 ADH_zinc_N PF00107.26 EEB06319.2 - 1.1e-17 64.3 0.0 2.9e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEB06319.2 - 3.1e-10 39.9 0.0 7.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEB06319.2 - 1.4e-09 39.1 0.0 2.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transferase PF02458.15 EEB06320.1 - 6.3e-25 87.7 0.0 1.5e-22 79.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family LRR_12 PF18837.1 EEB06320.1 - 0.32 10.7 1.9 5.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Leucine-rich repeat Ribosomal_L14e PF01929.17 EEB06321.1 - 9.6e-33 112.5 1.1 1.3e-32 112.1 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EEB06321.1 - 0.00092 19.1 1.2 0.00092 19.1 1.2 1.8 2 0 0 2 2 2 1 KOW motif DUF4800 PF16057.5 EEB06321.1 - 0.015 14.6 3.0 0.02 14.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) ubiquitin PF00240.23 EEB06322.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EEB06322.1 - 7e-32 109.1 12.1 1.1e-31 108.5 12.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EEB06322.1 - 1.9e-16 59.6 0.7 3e-16 59.0 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB06322.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB06322.1 - 0.0034 17.7 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB06322.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB06322.1 - 0.0065 16.6 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EEB06322.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EEB06322.1 - 0.026 15.1 0.1 0.03 14.9 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EEB06322.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Ribosomal_S26e PF01283.19 EEB06323.1 - 8.4e-55 183.8 8.5 9.9e-55 183.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 EEB06323.1 - 0.1 13.2 2.7 0.55 10.9 2.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Formyl_trans_N PF00551.19 EEB06325.1 - 3.3e-24 85.6 0.0 4.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EEB06325.1 - 1.5e-06 28.4 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Alba PF01918.21 EEB06326.1 - 6.3e-06 25.9 0.1 8.8e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Alba DapB_C PF05173.14 EEB06326.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Tctex-1 PF03645.13 EEB06327.1 - 3.9e-14 52.7 0.0 4.3e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family BiPBP_C PF06832.12 EEB06327.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DASH_Dad2 PF08654.10 EEB06328.1 - 2.2e-18 66.5 0.8 5.1e-18 65.3 0.8 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EEB06328.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 ALAD PF00490.21 EEB06329.1 - 5.5e-120 400.3 0.0 6.7e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Baculo_RING PF05883.11 EEB06329.1 - 0.068 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Pkinase PF00069.25 EEB06330.1 - 9.6e-25 87.4 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06330.1 - 5.8e-10 38.9 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB06330.1 - 7.1e-07 28.3 3.2 7.5e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Suf PF05843.14 EEB06330.1 - 6.6 6.6 11.5 7.9 6.4 10.3 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Nucleoporin_C PF03177.14 EEB06331.2 - 2.7e-135 452.4 22.9 3.4e-135 452.1 22.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EEB06331.2 - 1.1e-28 100.2 0.0 2.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like TRM13 PF05206.14 EEB06332.1 - 2.2e-67 227.3 0.0 4.2e-67 226.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 EEB06332.1 - 2.2e-08 33.8 0.5 5.9e-08 32.5 0.5 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 EEB06332.1 - 0.0057 16.7 3.1 0.05 13.6 3.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 EEB06333.1 - 5.9e-59 199.6 0.0 9.5e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06333.1 - 3.2e-23 82.3 0.0 4.9e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06333.1 - 2.7e-08 33.5 0.0 4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB06333.1 - 0.00023 20.6 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB06333.1 - 0.00067 19.6 0.3 0.11 12.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEB06333.1 - 0.00087 18.3 0.2 0.0022 17.0 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain PAS_9 PF13426.7 EEB06333.1 - 0.019 15.2 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 PAS domain Pkinase_fungal PF17667.1 EEB06333.1 - 0.071 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rif1_N PF12231.8 EEB06334.1 - 3.5e-92 309.3 6.4 6.1e-92 308.5 6.4 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal BSP_II PF05432.11 EEB06334.1 - 1.7 8.3 10.2 2.5 7.7 10.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TPP1 PF10341.9 EEB06335.1 - 4.6e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD FAM216B PF15107.6 EEB06335.1 - 0.0027 17.6 0.3 0.006 16.5 0.3 1.5 1 0 0 1 1 1 1 FAM216B protein family Ras PF00071.22 EEB06336.2 - 5.4e-55 185.4 0.0 7.1e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB06336.2 - 1.4e-32 112.5 0.0 2.6e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB06336.2 - 2.3e-10 40.2 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB06336.2 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB06336.2 - 6.1e-05 23.0 0.1 0.032 14.1 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEB06336.2 - 0.00038 20.5 0.0 0.00058 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEB06336.2 - 0.016 15.6 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EEB06336.2 - 0.041 13.3 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF4187 PF13821.6 EEB06337.1 - 3.1e-20 71.7 1.0 9.2e-20 70.2 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EEB06337.1 - 1.4e-07 31.3 0.2 2.7e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain DUF932 PF06067.11 EEB06337.1 - 0.039 13.7 0.9 0.049 13.4 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Baculo_p24 PF05073.12 EEB06337.1 - 0.063 13.1 0.5 0.084 12.6 0.5 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein G-patch_2 PF12656.7 EEB06337.1 - 0.19 11.8 0.3 0.19 11.8 0.3 2.0 3 0 0 3 3 3 0 G-patch domain Ribosomal_L37 PF08561.10 EEB06337.1 - 0.19 12.2 3.6 0.32 11.5 3.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF726 PF05277.12 EEB06338.1 - 5.7e-125 416.8 0.9 7.4e-125 416.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1682 PF07946.14 EEB06338.1 - 0.24 10.6 4.2 0.39 9.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PX PF00787.24 EEB06339.1 - 6.5e-23 80.9 0.1 2.4e-22 79.0 0.1 1.9 1 0 0 1 1 1 1 PX domain DASH_Dad1 PF08649.10 EEB06339.1 - 0.0012 19.0 3.3 0.096 12.9 0.2 3.0 2 0 0 2 2 2 1 DASH complex subunit Dad1 GAS PF13851.6 EEB06339.1 - 0.0013 18.1 13.9 0.0044 16.4 1.9 2.4 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding USP8_dimer PF08969.11 EEB06339.1 - 0.012 15.8 0.9 0.012 15.8 0.9 2.2 2 0 0 2 2 2 0 USP8 dimerisation domain SKA2 PF16740.5 EEB06339.1 - 0.12 12.1 8.2 1.5 8.6 0.7 2.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF2229 PF09989.9 EEB06339.1 - 0.19 11.3 2.3 3.7 7.2 0.5 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) BLOC1_2 PF10046.9 EEB06339.1 - 0.38 11.1 17.2 0.051 13.9 2.6 3.7 2 1 3 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EEB06339.1 - 0.64 10.1 9.9 8.3 6.5 0.7 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FIVAR PF07554.13 EEB06339.1 - 0.78 10.5 5.5 32 5.4 1.1 3.3 3 0 0 3 3 3 0 FIVAR domain T3SSipB PF16535.5 EEB06339.1 - 0.96 9.9 11.7 0.6 10.6 0.7 3.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB ACP_PD PF04336.12 EEB06339.1 - 1.1 9.7 5.2 0.96 9.9 0.8 2.9 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase zf-C4H2 PF10146.9 EEB06339.1 - 2.6 8.3 16.7 20 5.4 2.9 3.5 2 2 1 3 3 3 0 Zinc finger-containing protein L31 PF09784.9 EEB06339.1 - 5.6 7.5 8.3 1.5 9.3 1.0 3.1 2 2 1 3 3 3 0 Mitochondrial ribosomal protein L31 Phos_pyr_kin PF08543.12 EEB06340.1 - 3.5e-17 62.6 0.0 4.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EEB06340.1 - 9.5e-08 31.7 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase P34-Arc PF04045.14 EEB06341.1 - 4.8e-102 340.8 1.9 5.8e-102 340.5 1.9 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Nucleocap_ssRNA PF11128.8 EEB06341.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid cPLA2_C2 PF18695.1 EEB06341.1 - 0.16 11.9 0.2 0.78 9.8 0.0 1.9 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain NuA4 PF09340.10 EEB06342.1 - 5.4e-24 83.9 0.7 5.4e-24 83.9 0.7 2.1 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AATF-Che1 PF13339.6 EEB06342.1 - 0.016 15.9 1.0 0.023 15.4 1.0 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor RabGAP-TBC PF00566.18 EEB06343.1 - 5e-40 137.4 0.1 7.7e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_S13_N PF08069.12 EEB06344.1 - 1.2e-28 98.9 0.3 2.4e-28 98.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EEB06344.1 - 2.6e-15 56.4 0.3 3.9e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Rax2 PF12768.7 EEB06345.2 - 4.1e-14 52.5 17.8 5.2e-14 52.2 2.1 5.1 4 1 1 5 5 5 2 Cortical protein marker for cell polarity Kelch_4 PF13418.6 EEB06345.2 - 0.00029 20.8 1.1 0.53 10.3 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EEB06345.2 - 0.059 13.4 1.8 1.2 9.2 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 EEB06345.2 - 0.12 12.8 4.2 1e+02 3.4 0.0 5.1 4 0 0 4 4 4 0 Kelch motif DAD PF02109.16 EEB06346.1 - 1.2e-38 131.8 7.0 1.3e-38 131.6 7.0 1.0 1 0 0 1 1 1 1 DAD family NFACT-R_1 PF05670.13 EEB06347.2 - 3.3e-17 63.1 1.0 9.8e-17 61.6 0.1 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain NGP1NT PF08153.12 EEB06348.2 - 3.4e-51 172.8 0.1 5.3e-51 172.2 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EEB06348.2 - 4.6e-16 58.9 0.0 5.8e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 EEB06348.2 - 9.6e-06 25.2 0.1 0.029 13.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 EEB06348.2 - 3.2e-05 23.5 0.0 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEB06348.2 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EEB06348.2 - 0.00039 20.5 0.4 0.095 12.8 0.0 3.5 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.27 EEB06348.2 - 0.0046 16.5 0.3 0.43 10.1 0.1 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain LRR_6 PF13516.6 EEB06349.1 - 8e-05 22.4 2.6 5.2 7.4 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 EEB06349.1 - 0.0019 18.5 10.8 0.21 12.0 1.5 4.9 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEB06349.1 - 0.098 12.4 3.0 2.7 7.8 0.2 3.9 3 2 1 4 4 4 0 Leucine rich repeat Ion_trans PF00520.31 EEB06350.2 - 1.7e-81 273.1 88.2 9.4e-29 100.3 10.5 5.4 4 2 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 EEB06350.2 - 0.0033 16.2 8.1 0.0033 16.2 8.1 7.3 5 3 2 7 7 7 5 Polycystin cation channel GPHH PF16905.5 EEB06350.2 - 0.014 15.1 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated V-ATPase_C PF03223.15 EEB06353.1 - 5.7e-118 394.5 4.5 6.5e-118 394.3 4.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF3412 PF11892.8 EEB06353.1 - 0.077 13.1 0.1 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) Cation_ATPase_C PF00689.21 EEB06354.2 - 2.8e-44 151.0 10.4 2.8e-44 151.0 10.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EEB06354.2 - 4.9e-40 137.0 1.7 4.9e-40 137.0 1.7 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EEB06354.2 - 4.6e-17 63.0 0.2 8.7e-16 58.8 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB06354.2 - 2e-12 47.0 0.0 4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEB06354.2 - 3.5e-07 29.8 0.0 1.3e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEB06354.2 - 8.6e-07 28.9 0.3 5.8e-05 23.0 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EEB06354.2 - 0.0097 14.8 0.4 0.0097 14.8 0.4 2.6 4 0 0 4 4 4 1 Lipopolysaccharide export system permease LptF/LptG Cyclin_N PF00134.23 EEB06355.1 - 9.3e-45 151.5 0.1 1e-41 141.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB06355.1 - 2.4e-27 95.4 0.1 3.9e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain BCDHK_Adom3 PF10436.9 EEB06356.1 - 3.7e-44 150.4 0.0 5.2e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEB06356.1 - 1.9e-12 47.7 0.0 5e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEB06356.1 - 3.9e-05 23.5 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med11 PF10280.9 EEB06357.1 - 5e-10 40.0 0.5 6.5e-10 39.6 0.5 1.2 1 0 0 1 1 1 1 Mediator complex protein ALS_ss_C PF10369.9 EEB06357.1 - 0.045 14.0 0.1 0.076 13.2 0.1 1.3 1 0 0 1 1 1 0 Small subunit of acetolactate synthase Ala_racemase_N PF01168.20 EEB06358.1 - 2.4e-30 105.8 0.0 2.9e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HAD_2 PF13419.6 EEB06359.1 - 0.003 17.6 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF5088 PF17008.5 EEB06359.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) BCS1_N PF08740.11 EEB06360.1 - 3e-46 157.7 0.1 4e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EEB06360.1 - 5.1e-19 69.0 0.0 1.5e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EEB06360.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB06360.1 - 0.0069 16.8 0.0 0.032 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EEB06360.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EEB06360.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EEB06360.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EEB06360.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEB06360.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EEB06360.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EEB06360.1 - 0.17 12.1 0.0 0.58 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain SLAC1 PF03595.17 EEB06361.1 - 9.5e-71 238.7 57.5 1.1e-70 238.5 57.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel E1_DerP2_DerF2 PF02221.15 EEB06362.1 - 1.1e-20 74.5 0.1 1.3e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EEB06362.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.5 1 1 0 1 1 1 1 ML-like domain NAR2 PF16974.5 EEB06362.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Myb_Cef PF11831.8 EEB06363.2 - 2.6e-32 112.3 10.5 2.6e-32 112.3 10.5 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EEB06363.2 - 4.5e-22 78.0 6.3 2.6e-11 43.5 1.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB06363.2 - 2.4e-19 69.3 7.4 4.1e-13 49.4 3.4 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Borrelia_orfA PF02414.15 EEB06363.2 - 0.0025 17.5 1.8 0.0025 17.5 1.8 2.6 2 1 0 2 2 2 1 Borrelia ORF-A CENP-X PF09415.10 EEB06363.2 - 1.1 9.6 6.4 3.7 8.0 0.5 3.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Yip1 PF04893.17 EEB06364.1 - 7.4e-12 45.3 12.7 1e-11 44.9 12.7 1.3 1 1 0 1 1 1 1 Yip1 domain Rad51 PF08423.11 EEB06365.1 - 2.8e-130 433.1 0.0 3.7e-130 432.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EEB06365.1 - 5.4e-12 45.7 0.0 7.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EEB06365.1 - 6.6e-11 42.1 0.0 9.4e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EEB06365.1 - 3.4e-06 27.6 0.2 1.5e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EEB06365.1 - 4.3e-06 26.2 0.1 9.3e-06 25.2 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EEB06365.1 - 0.016 14.5 0.1 0.084 12.2 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ribosomal_60s PF00428.19 EEB06366.1 - 2.4e-27 95.4 12.1 3e-27 95.0 12.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CSTF2_hinge PF14327.6 EEB06367.1 - 7.4e-21 74.4 0.4 7.4e-21 74.4 0.4 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EEB06367.1 - 1.3e-19 69.8 0.0 1.9e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EEB06367.1 - 7.9e-10 38.2 7.7 1.4e-09 37.4 7.7 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EEB06367.1 - 0.029 14.5 0.0 0.082 13.0 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif Ribosomal_L3 PF00297.22 EEB06368.1 - 2.3e-19 69.6 3.5 7.4e-16 58.1 1.6 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 NQRA_SLBB PF11973.8 EEB06368.1 - 0.17 12.6 0.3 1.8 9.3 0.0 2.5 3 0 0 3 3 3 0 NQRA C-terminal domain ADH_N PF08240.12 EEB06369.1 - 1.4e-34 118.3 0.7 3e-34 117.2 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB06369.1 - 2.4e-21 76.1 0.3 3.5e-21 75.5 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEB06369.1 - 0.0021 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEB06369.1 - 0.0027 18.8 0.0 0.0048 18.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEB06369.1 - 0.0057 16.0 0.3 0.012 14.9 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EEB06369.1 - 0.13 11.7 0.1 0.27 10.6 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase TRAPP PF04051.16 EEB06370.1 - 2.6e-29 101.8 0.0 3.2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIG-L PF02585.17 EEB06371.1 - 1.2e-22 80.9 0.0 2.1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glutaredoxin PF00462.24 EEB06372.1 - 6.7e-16 58.3 0.0 1.8e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin zf-CSL PF05207.13 EEB06373.1 - 3e-22 78.1 0.5 3e-22 78.1 0.5 1.3 2 0 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EEB06373.1 - 0.001 19.1 0.2 0.0017 18.4 0.2 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-RING_7 PF02591.15 EEB06373.1 - 0.0085 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 EEB06373.1 - 0.087 12.8 0.3 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain MutS_V PF00488.21 EEB06374.1 - 1.9e-63 213.9 0.0 3.6e-63 213.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEB06374.1 - 8.6e-33 114.2 0.2 1.8e-32 113.1 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEB06374.1 - 2.1e-28 98.8 0.0 4.5e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EEB06374.1 - 7.6e-10 39.2 0.1 8.2e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EEB06374.1 - 0.0057 17.0 0.1 0.016 15.6 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV Ribosomal_L1 PF00687.21 EEB06375.1 - 2.5e-49 167.8 0.8 2.5e-49 167.8 0.8 2.0 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Tfb4 PF03850.14 EEB06375.1 - 0.29 10.6 3.3 0.52 9.8 3.3 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF966 PF06136.13 EEB06375.1 - 0.75 9.5 13.1 1.1 9.0 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.7 EEB06375.1 - 2.1 6.4 10.8 2.7 6.0 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PCM1_C PF15717.5 EEB06375.1 - 2.1 7.0 14.2 3.4 6.3 14.2 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Presenilin PF01080.17 EEB06375.1 - 7.9 5.1 14.2 11 4.6 14.2 1.2 1 0 0 1 1 1 0 Presenilin DLIC PF05783.11 EEB06375.1 - 8.5 5.1 12.9 13 4.5 12.9 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Brr6_like_C_C PF10104.9 EEB06377.1 - 3.2e-41 140.2 3.9 5.1e-41 139.6 3.9 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PIG-F PF06699.11 EEB06377.1 - 0.0057 16.8 1.7 0.014 15.5 1.7 1.6 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F CDC45 PF02724.14 EEB06377.1 - 0.021 13.1 0.2 0.026 12.8 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX29 PF15839.5 EEB06377.1 - 0.025 15.2 1.6 0.58 10.8 0.0 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein Ctr PF04145.15 EEB06377.1 - 1.5 9.5 5.2 4.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Pkinase PF00069.25 EEB06378.2 - 2.2e-40 138.7 0.1 7.1e-22 78.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06378.2 - 1.2e-12 47.7 0.0 4.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB06378.2 - 0.022 13.5 1.5 0.18 10.5 0.2 2.1 1 1 1 2 2 2 0 Fungal protein kinase APH PF01636.23 EEB06378.2 - 0.094 12.6 0.2 0.58 10.0 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family CDC24_OB3 PF17244.2 EEB06379.2 - 5.9e-25 88.3 1.0 1e-24 87.5 1.0 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 EEB06379.2 - 2e-15 57.5 0.1 5.1e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 EEB06379.2 - 3.1e-15 56.3 0.2 8.9e-15 54.9 0.2 1.8 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 Abhydrolase_3 PF07859.13 EEB06380.2 - 7.4e-07 29.2 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EEB06380.2 - 9.1e-06 24.8 0.2 0.0019 17.2 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family FGGY_C PF02782.16 EEB06380.2 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Chlorophyllase PF07224.11 EEB06380.2 - 0.052 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase YfkB PF08756.10 EEB06380.2 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain DLH PF01738.18 EEB06380.2 - 0.13 11.7 0.0 1.3 8.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Methyltransf_16 PF10294.9 EEB06381.1 - 1.8e-17 63.6 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EEB06381.1 - 0.00061 19.1 0.1 0.00096 18.5 0.1 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 EEB06381.1 - 0.0013 19.4 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB06381.1 - 0.0045 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EEB06381.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EEB06381.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family PS_pyruv_trans PF04230.13 EEB06382.1 - 2.8e-24 86.5 0.4 1.9e-23 83.8 0.4 1.9 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase Glyco_transf_20 PF00982.21 EEB06383.1 - 1.1e-157 525.5 0.9 1.5e-157 525.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEB06383.1 - 1.6e-36 125.6 0.0 2.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase MBA1 PF07961.11 EEB06383.1 - 0.05 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 MBA1-like protein CPDase PF07823.11 EEB06384.1 - 3e-12 46.7 0.0 4.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EEB06384.1 - 0.01 15.8 0.1 0.064 13.2 0.1 1.9 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily RTT107_BRCT_5 PF16770.5 EEB06385.2 - 1.9e-06 27.7 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EEB06385.2 - 0.00022 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Peptidase_M16_M PF16187.5 EEB06386.1 - 1.5e-84 283.6 0.7 2.3e-84 283.0 0.7 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EEB06386.1 - 9.7e-38 129.5 0.0 2.8e-37 128.0 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEB06386.1 - 1.6e-33 116.3 0.1 1.5e-20 74.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Syd PF07348.12 EEB06386.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Syd protein (SUKH-2) MPP6 PF10175.9 EEB06387.1 - 4.7e-14 53.0 14.8 3.2e-13 50.3 14.8 2.0 1 1 0 1 1 1 1 M-phase phosphoprotein 6 CDC45 PF02724.14 EEB06387.1 - 1.3 7.2 9.6 1.4 7.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein 2-Hacid_dh_C PF02826.19 EEB06388.1 - 1.2e-57 194.1 0.0 1.6e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEB06388.1 - 6.3e-18 64.7 0.0 7.2e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEB06388.1 - 0.00033 20.9 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEB06388.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DBR1 PF05011.13 EEB06389.1 - 8.1e-38 130.0 0.5 1.2e-37 129.5 0.5 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EEB06389.1 - 1.4e-09 38.8 0.2 2.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EEB06389.1 - 0.0039 16.6 0.2 0.03 13.6 0.2 2.3 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Methyltransf_23 PF13489.6 EEB06390.1 - 1.9e-10 40.8 0.0 4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB06390.1 - 2.8e-05 24.0 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEB06390.1 - 4.1e-05 24.2 0.1 0.00057 20.5 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Rhodanese PF00581.20 EEB06390.1 - 0.00028 21.3 0.0 0.00062 20.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain TehB PF03848.14 EEB06390.1 - 0.00031 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EEB06390.1 - 0.0026 17.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain TPMT PF05724.11 EEB06390.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EEB06390.1 - 0.0087 16.7 0.0 0.14 12.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB06390.1 - 0.011 16.5 0.0 0.041 14.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EEB06390.1 - 0.013 15.1 0.0 0.078 12.6 0.0 2.0 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 EEB06390.1 - 0.032 13.7 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 EEB06390.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EEB06390.1 - 0.11 12.3 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MetW PF07021.12 EEB06390.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EEB06390.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) E1-E2_ATPase PF00122.20 EEB06391.1 - 1.1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EEB06391.1 - 1.1e-18 68.3 0.0 7.8e-11 42.7 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB06391.1 - 8.7e-07 28.9 0.1 2.2e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEB06391.1 - 0.0019 18.0 1.2 0.032 14.0 0.2 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EEB06391.1 - 0.018 14.6 0.3 0.05 13.1 0.1 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SHS2_Rpb7-N PF03876.17 EEB06392.1 - 1.1e-18 67.3 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EEB06392.1 - 1.1e-12 48.1 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EEB06392.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 C2 PF00168.30 EEB06393.1 - 2.4e-62 207.6 0.0 2.3e-24 85.6 0.0 5.4 5 0 0 5 5 5 5 C2 domain CEP76-C2 PF15627.6 EEB06393.1 - 0.002 17.7 0.0 0.66 9.5 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain RPN2_C PF18004.1 EEB06393.1 - 0.87 9.5 8.5 1.5 8.7 8.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GTP_EFTU PF00009.27 EEB06395.1 - 2e-65 220.0 0.1 2.9e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEB06395.1 - 1.6e-30 105.4 0.0 4.8e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EEB06395.1 - 3e-20 72.0 0.0 6.8e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB06395.1 - 1.6e-12 47.6 0.0 4.7e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEB06395.1 - 1.8e-12 47.2 0.0 4.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEB06395.1 - 0.00065 19.8 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zn_clus PF00172.18 EEB06396.1 - 4e-08 33.2 10.2 7.3e-08 32.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 EEB06397.1 - 9.2e-26 89.5 0.0 1.9e-10 40.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB06397.1 - 0.00034 20.4 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EEB06397.1 - 0.00084 19.3 0.0 0.062 13.4 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 EEB06397.1 - 0.013 15.5 0.2 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EEB06397.1 - 0.049 13.8 0.1 0.55 10.5 0.1 2.2 2 0 0 2 2 2 0 RRM-like domain WD40 PF00400.32 EEB06398.1 - 3.7e-30 103.5 21.5 2.2e-05 25.1 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06398.1 - 2.3e-07 31.0 0.0 1.1 9.6 0.0 4.8 1 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB06398.1 - 0.00047 19.2 0.2 0.14 11.1 0.0 3.9 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EEB06398.1 - 0.051 13.3 0.4 0.27 10.9 0.4 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 EEB06398.1 - 0.057 12.0 0.4 0.88 8.1 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 LisH PF08513.11 EEB06399.1 - 6.1e-09 35.5 0.1 1.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 LisH TIM21 PF08294.11 EEB06400.1 - 1.3e-31 109.4 0.0 1.7e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EEB06400.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 UDPGP PF01704.18 EEB06401.1 - 2.5e-35 121.9 0.0 3.5e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Baseplate PF16774.5 EEB06401.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Baseplate protein RNA_pol_A_bac PF01000.26 EEB06402.1 - 6.6e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEB06402.1 - 2.1e-18 65.5 0.0 3.7e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EMP70 PF02990.16 EEB06403.1 - 1.4e-135 453.0 20.5 1.8e-135 452.6 20.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1129 PF06570.11 EEB06403.1 - 0.0014 18.2 1.3 0.0014 18.2 1.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) PPR_1 PF12854.7 EEB06404.2 - 0.0025 17.5 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.6 EEB06404.2 - 0.073 13.3 0.5 0.55 10.5 0.1 2.7 2 1 0 2 2 2 0 PPR repeat family PPR_3 PF13812.6 EEB06404.2 - 0.1 12.7 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain V-ATPase_G PF03179.15 EEB06405.2 - 2.6e-25 89.0 8.8 2.9e-25 88.8 8.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HEPN_MAE_28990 PF18737.1 EEB06405.2 - 0.0044 17.0 1.2 0.0044 17.0 1.2 1.9 1 1 1 2 2 2 1 MAE_28990/MAE_18760-like HEPN AAA_lid_6 PF17866.1 EEB06405.2 - 0.011 15.9 0.3 0.023 14.9 0.3 1.6 1 0 0 1 1 1 0 AAA lid domain DUF3552 PF12072.8 EEB06405.2 - 0.015 14.7 11.7 0.1 12.0 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) S_layer_C PF05124.12 EEB06405.2 - 0.02 14.9 3.3 0.022 14.8 3.3 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF4145 PF13643.6 EEB06405.2 - 0.026 14.6 0.2 0.059 13.5 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) ATP-synt_B PF00430.18 EEB06405.2 - 0.16 12.1 9.4 0.1 12.7 4.9 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF883 PF05957.13 EEB06405.2 - 4.1 8.1 7.1 6.1 7.5 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EEB06405.2 - 8.7 7.0 9.2 1.9e+02 2.6 9.2 2.1 1 1 0 1 1 1 0 YtxH-like protein SAM_2 PF07647.17 EEB06406.1 - 1.3e-13 50.8 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EEB06406.1 - 4e-13 49.8 0.0 8.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 EEB06406.1 - 5.8e-10 38.6 0.1 1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 EEB06406.1 - 8.7e-09 35.7 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EEB06406.1 - 2.5e-08 33.7 0.0 4.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EEB06406.1 - 1.9e-06 28.2 0.2 6.9e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EEB06406.1 - 0.0022 18.2 0.1 0.025 14.8 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 EEB06406.1 - 0.0057 16.3 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.16 EEB06406.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ras PF00071.22 EEB06407.1 - 4.2e-48 163.0 0.0 5.1e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB06407.1 - 1.1e-28 99.9 0.0 2.4e-28 98.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB06407.1 - 7e-11 41.9 0.0 8.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB06407.1 - 0.00024 20.5 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 EEB06407.1 - 0.00029 21.2 0.1 0.0024 18.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EEB06407.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EEB06407.1 - 0.0044 16.2 0.8 0.9 8.6 0.1 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 EEB06407.1 - 0.018 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EEB06407.1 - 0.032 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EEB06407.1 - 0.035 14.0 0.1 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EEB06407.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEB06407.1 - 0.089 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EEB06407.1 - 0.11 12.7 0.5 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EEB06407.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 EEB06407.1 - 0.15 11.3 0.3 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 EEB06407.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-MIZ PF02891.20 EEB06408.1 - 9.4e-12 44.5 0.9 2.2e-11 43.3 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Glyco_hydro_42M PF08532.10 EEB06409.2 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain RRM_1 PF00076.22 EEB06410.1 - 1.2e-12 47.4 0.1 4.1e-05 23.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB06410.1 - 0.013 15.6 0.1 0.031 14.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Vir_act_alpha_C PF10400.9 EEB06410.1 - 0.47 11.2 3.3 0.22 12.2 0.4 1.9 2 0 0 2 2 2 0 Virulence activator alpha C-term RNA_pol_Rbc25 PF08292.12 EEB06410.1 - 0.62 10.3 3.9 0.34 11.2 1.0 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Sel1 PF08238.12 EEB06411.1 - 1.5e-08 35.0 10.6 0.019 15.7 0.0 6.8 7 1 0 7 7 7 2 Sel1 repeat TPR_2 PF07719.17 EEB06411.1 - 1.9e-08 33.8 0.1 3.2e-05 23.7 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06411.1 - 1.4e-07 31.0 0.2 1e-05 25.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06411.1 - 3.5e-05 24.4 6.6 0.00031 21.3 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06411.1 - 4.9e-05 23.2 0.1 0.00032 20.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06411.1 - 8.7e-05 23.0 2.8 0.023 15.5 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06411.1 - 0.00031 20.6 0.2 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06411.1 - 0.0028 18.2 0.8 0.028 15.0 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06411.1 - 0.0061 16.8 5.8 0.0097 16.2 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEB06411.1 - 0.0066 16.3 0.4 0.05 13.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEB06411.1 - 0.021 15.2 0.2 2.4 8.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEB06411.1 - 0.091 12.5 0.6 5.8 6.7 0.1 2.9 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 EEB06411.1 - 0.65 10.6 3.8 2.9 8.5 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Nop16 PF09420.10 EEB06412.1 - 2.3e-52 178.1 4.6 2.6e-52 177.9 4.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2543 PF10820.8 EEB06412.1 - 0.098 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) IGPS PF00218.21 EEB06413.1 - 3e-94 314.9 0.2 5.3e-94 314.1 0.2 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EEB06413.1 - 2.4e-50 171.0 0.1 6.7e-45 153.3 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EEB06413.1 - 1.7e-45 155.2 0.0 2.9e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEB06413.1 - 4.3e-07 29.9 0.1 3.9e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EEB06413.1 - 0.00082 19.2 1.5 0.045 13.5 0.2 3.3 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EEB06413.1 - 0.0012 18.3 0.2 0.13 11.7 0.0 2.7 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 EEB06413.1 - 0.0056 15.8 0.0 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EEB06413.1 - 0.01 15.1 0.6 0.24 10.6 0.0 2.8 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Aldolase PF01081.19 EEB06413.1 - 0.036 13.5 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 KDPG and KHG aldolase TMP-TENI PF02581.17 EEB06413.1 - 0.038 13.3 0.3 0.51 9.6 0.1 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase Arf PF00025.21 EEB06414.1 - 3.5e-74 248.0 0.0 4.1e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEB06414.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEB06414.1 - 6.1e-13 48.7 0.0 7.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEB06414.1 - 8e-13 48.3 1.1 2.2e-08 33.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EEB06414.1 - 3.7e-12 46.0 0.0 4.5e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EEB06414.1 - 3.7e-10 39.6 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB06414.1 - 0.00027 21.0 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEB06414.1 - 0.0012 18.3 0.5 0.0052 16.1 0.5 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase ADH_N PF08240.12 EEB06415.1 - 2.9e-25 88.3 1.9 2.9e-25 88.3 1.9 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB06415.1 - 2.2e-24 85.9 0.4 3.7e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB06415.1 - 8.2e-05 23.7 0.0 0.00017 22.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEB06415.1 - 0.00016 21.1 1.2 0.0003 20.1 0.9 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEB06415.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EEB06415.1 - 0.0055 17.0 0.1 0.0096 16.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EEB06415.1 - 0.034 14.4 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 EEB06415.1 - 0.076 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EEB06415.1 - 0.085 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ACBP PF00887.19 EEB06416.2 - 3.5e-28 97.6 1.0 4.4e-28 97.3 1.0 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Sec34 PF04136.15 EEB06417.2 - 8.5e-33 113.3 3.2 8.5e-33 113.3 3.2 3.2 4 0 0 4 4 4 1 Sec34-like family DUF3772 PF12607.8 EEB06417.2 - 0.0043 16.8 0.1 0.017 14.8 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3772) UPF0121 PF03661.13 EEB06418.1 - 1.4e-38 132.6 17.3 1.7e-38 132.4 17.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Lyase_1 PF00206.20 EEB06419.1 - 8.4e-102 340.7 0.0 1.5e-101 340.0 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 EEB06419.1 - 2.9e-24 85.6 0.1 6.7e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal RED_N PF07808.13 EEB06420.1 - 7.7e-05 22.4 13.9 7.7e-05 22.4 13.9 3.2 2 1 1 3 3 3 1 RED-like protein N-terminal region SurA_N_3 PF13624.6 EEB06420.1 - 7.4 6.3 7.8 17 5.2 0.3 2.4 2 0 0 2 2 2 0 SurA N-terminal domain Ribonucleas_3_3 PF14622.6 EEB06421.2 - 5.2e-34 117.2 0.0 6.9e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEB06421.2 - 0.0018 18.9 0.0 0.0032 18.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain SID PF11778.8 EEB06422.1 - 1.1e-07 32.0 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Septation initiation DUF3019 PF11456.8 EEB06422.1 - 0.32 11.5 7.9 0.32 11.5 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) PLU-1 PF08429.11 EEB06423.2 - 1.8e-74 250.9 19.3 1.1e-69 235.2 14.7 2.5 3 0 0 3 3 3 2 PLU-1-like protein JmjC PF02373.22 EEB06423.2 - 3.5e-26 91.9 0.1 1.1e-25 90.3 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EEB06423.2 - 4.2e-16 58.6 55.9 1.5e-06 28.0 8.5 4.3 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 EEB06423.2 - 1.4e-09 38.2 2.6 1.4e-09 38.2 2.6 3.5 3 0 0 3 3 3 1 C5HC2 zinc finger bPH_4 PF06713.11 EEB06423.2 - 0.04 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial PH domain Med10 PF09748.9 EEB06423.2 - 0.047 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex JmjN PF02375.17 EEB06423.2 - 0.048 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 jmjN domain PHD_3 PF13922.6 EEB06423.2 - 0.18 12.2 15.5 0.018 15.4 2.2 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf-PHD-like PF15446.6 EEB06423.2 - 9.5 5.8 24.0 0.43 10.2 1.0 3.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain MTHFR PF02219.17 EEB06424.1 - 6.2e-107 357.2 0.1 8.1e-107 356.8 0.1 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Kdo PF06293.14 EEB06424.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SEP PF08059.13 EEB06425.1 - 4e-23 81.8 0.0 8.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EEB06425.1 - 5.6e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EEB06425.1 - 3.3e-06 26.8 0.1 6.3e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EEB06425.1 - 0.001 18.7 0.1 0.0025 17.4 0.0 1.7 2 0 0 2 2 2 1 TAP C-terminal domain NPDC1 PF06809.11 EEB06425.1 - 0.013 14.6 0.4 0.013 14.6 0.4 2.0 2 1 1 3 3 3 0 Neural proliferation differentiation control-1 protein (NPDC1) Ribosomal_S6 PF01250.17 EEB06426.1 - 1.5e-16 60.4 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 RRM_1 PF00076.22 EEB06427.1 - 3.7e-31 106.8 1.9 1.1e-14 54.0 0.4 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB06427.1 - 0.00088 19.3 0.2 0.011 15.8 0.0 2.8 3 1 1 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EEB06427.1 - 0.0039 17.2 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EEB06427.1 - 0.096 12.8 0.9 18 5.5 0.2 2.6 2 0 0 2 2 2 0 Limkain b1 RRM_occluded PF16842.5 EEB06427.1 - 0.15 11.9 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Scramblase PF03803.15 EEB06428.2 - 3.2e-67 226.1 0.0 4e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Scramblase ATP-synt_ab PF00006.25 EEB06429.2 - 9.2e-108 358.8 0.0 1.8e-107 357.9 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 EEB06429.2 - 1.2e-90 303.4 0.0 1.9e-90 302.8 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 EEB06429.2 - 2.6e-45 153.2 0.0 5.7e-45 152.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 EEB06429.2 - 7e-34 116.3 0.1 3.7e-28 97.9 0.0 2.7 3 0 0 3 3 3 2 Homing endonuclease ATP-synt_ab_N PF02874.23 EEB06429.2 - 4e-14 52.9 1.4 9.6e-14 51.7 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 EEB06429.2 - 2.5e-07 30.9 0.0 8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 LAGLIDADG-like domain Hint PF01079.20 EEB06429.2 - 0.001 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 EEB06429.2 - 0.0069 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 Hint domain DUF4567 PF15131.6 EEB06429.2 - 0.19 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) WD40 PF00400.32 EEB06430.1 - 1.4e-32 111.2 13.7 5.8e-07 30.1 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06430.1 - 3.3e-10 40.1 2.0 0.0093 16.3 0.0 4.7 1 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEB06430.1 - 3.8e-05 22.9 0.3 0.19 10.8 0.0 3.0 3 0 0 3 3 3 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 EEB06430.1 - 0.00022 19.9 0.6 0.37 9.3 0.0 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EEB06430.1 - 0.0014 18.0 0.0 0.0077 15.6 0.0 2.0 1 1 1 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 EEB06430.1 - 0.0065 15.4 0.1 3.5 6.4 0.0 3.0 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 EEB06430.1 - 0.034 12.9 0.1 0.77 8.4 0.1 2.7 1 1 0 1 1 1 0 Nup133 N terminal like zf-ANAPC11 PF12861.7 EEB06431.1 - 2e-44 149.5 8.6 2.2e-44 149.4 8.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEB06431.1 - 9.4e-22 77.1 11.9 1.3e-21 76.6 11.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEB06431.1 - 6.6e-07 29.6 16.3 9.6e-07 29.0 10.3 2.3 1 1 1 2 2 2 1 Ring finger domain zf-Nse PF11789.8 EEB06431.1 - 0.0003 20.5 3.7 0.00043 20.0 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EEB06431.1 - 0.0016 18.4 10.2 0.0078 16.2 10.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEB06431.1 - 0.0057 16.5 13.3 0.026 14.4 13.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEB06431.1 - 0.0079 15.8 15.9 0.03 13.9 14.0 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EEB06431.1 - 0.073 12.9 0.5 0.073 12.9 0.5 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EEB06431.1 - 0.09 12.8 15.8 1.6 8.7 16.1 2.8 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 EEB06431.1 - 0.76 10.0 17.5 10 6.4 16.2 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 EEB06431.1 - 0.88 9.5 18.4 0.39 10.6 14.1 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EEB06431.1 - 1.2 9.4 11.8 0.34 11.1 6.3 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 EEB06431.1 - 4 7.3 16.1 20 5.0 16.1 2.0 1 1 0 1 1 1 0 RING-like zinc finger Rad50_zn_hook PF04423.14 EEB06431.1 - 7.8 6.4 9.5 9 6.2 4.9 2.7 2 1 0 2 2 2 0 Rad50 zinc hook motif Ribosomal_L19 PF01245.20 EEB06432.1 - 6.3e-13 48.6 0.0 8.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 GHMP_kinases_N PF00288.26 EEB06433.2 - 6.9e-14 51.8 0.4 1.7e-13 50.6 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEB06433.2 - 8.4e-08 32.5 0.0 2.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Perilipin PF03036.16 EEB06433.2 - 0.027 13.5 0.6 0.075 12.1 0.1 1.7 2 0 0 2 2 2 0 Perilipin family Rx_N PF18052.1 EEB06433.2 - 0.12 12.7 0.0 9.7 6.5 0.0 2.5 2 1 0 2 2 2 0 Rx N-terminal domain DNA_pol3_a_NI PF14480.6 EEB06433.2 - 0.22 11.6 0.4 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I GIY-YIG PF01541.24 EEB06434.1 - 3.4e-14 52.9 0.0 7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain WBS28 PF15164.6 EEB06434.1 - 0.01 15.2 0.5 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue SNX17_FERM_C PF18116.1 EEB06434.1 - 0.047 13.8 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain T5orf172 PF10544.9 EEB06434.1 - 0.078 13.5 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain FANCL_C PF11793.8 EEB06434.1 - 0.092 12.9 8.0 0.17 12.0 6.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EEB06434.1 - 3.1 8.1 8.3 2 8.7 5.5 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain TFIID-31kDa PF02291.15 EEB06435.1 - 1e-49 167.6 0.0 1.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EEB06435.1 - 0.061 13.4 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold RTC PF01137.21 EEB06436.1 - 1.6e-47 161.6 0.0 1.8e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EEB06436.1 - 7.2e-35 119.6 0.0 1.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ribosomal_L6 PF00347.23 EEB06438.1 - 7.2e-23 81.1 0.0 7.9e-13 48.9 0.0 2.4 2 1 0 2 2 2 2 Ribosomal protein L6 MINDY_DUB PF04424.13 EEB06441.1 - 1.7e-11 44.1 0.9 2.8e-11 43.5 0.3 1.7 1 1 1 2 2 2 1 MINDY deubiquitinase SET PF00856.28 EEB06442.1 - 6.5e-07 29.9 0.0 2e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 SET domain SUI1 PF01253.22 EEB06446.1 - 1.1e-21 77.2 1.1 6e-21 74.8 0.7 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 Sortilin-Vps10 PF15902.5 EEB06447.1 - 1.7e-224 745.7 0.1 1.2e-126 423.2 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EEB06447.1 - 2.4e-69 233.0 9.6 2.7e-40 138.5 0.4 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EEB06447.1 - 1.2e-05 24.5 37.6 4.6 7.6 0.0 11.4 12 0 0 12 12 12 5 BNR/Asp-box repeat PSII_BNR PF14870.6 EEB06447.1 - 3.4e-05 23.2 0.0 0.0021 17.4 0.0 3.6 4 1 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 AAA PF00004.29 EEB06448.1 - 1.2e-39 135.7 0.0 2.2e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB06448.1 - 6.1e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EEB06448.1 - 4.5e-05 23.7 0.0 0.0034 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EEB06448.1 - 7.7e-05 22.7 0.1 0.00036 20.6 0.0 2.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEB06448.1 - 0.00028 21.1 0.0 0.00085 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEB06448.1 - 0.0005 20.5 0.1 0.0098 16.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EEB06448.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EEB06448.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EEB06448.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEB06448.1 - 0.015 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEB06448.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEB06448.1 - 0.022 14.5 0.2 0.073 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEB06448.1 - 0.026 14.9 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EEB06448.1 - 0.032 14.8 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEB06448.1 - 0.049 13.5 0.0 6.1 6.7 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EEB06448.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EEB06448.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EEB06448.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EEB06448.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EEB06448.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UCR_hinge PF02320.16 EEB06449.1 - 8.2e-21 74.0 8.3 2.8e-20 72.3 8.3 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Dicty_REP PF05086.12 EEB06449.1 - 0.082 10.9 8.3 0.1 10.5 8.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4551 PF15087.6 EEB06449.1 - 9.2 5.0 15.7 11 4.8 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PMT PF02366.18 EEB06450.1 - 3.7e-88 295.2 21.1 3.7e-88 295.2 21.1 2.3 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEB06450.1 - 5.2e-61 205.7 9.0 5.2e-61 205.7 9.0 3.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEB06450.1 - 7.8e-17 61.7 0.1 1.2e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF4239 PF14023.6 EEB06450.1 - 0.023 14.4 1.3 0.048 13.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) adh_short PF00106.25 EEB06451.1 - 1.7e-50 171.2 0.5 2e-50 171.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB06451.1 - 1.1e-32 113.4 0.3 1.3e-32 113.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB06451.1 - 1.8e-13 50.8 0.0 2.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEB06451.1 - 0.00089 18.5 0.4 0.0013 18.0 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EEB06451.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ctr PF04145.15 EEB06452.2 - 3.4e-15 57.0 13.0 4e-14 53.5 13.0 2.0 1 1 0 1 1 1 1 Ctr copper transporter family DUF485 PF04341.12 EEB06452.2 - 0.0094 15.9 5.9 1.7 8.7 3.3 2.5 2 1 0 2 2 2 2 Protein of unknown function, DUF485 Noc2 PF03715.13 EEB06453.1 - 2.6e-107 358.5 1.7 2.6e-107 358.5 1.7 2.3 2 0 0 2 2 2 1 Noc2p family XPC-binding PF09280.11 EEB06453.1 - 0.089 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 XPC-binding domain DDHD PF02862.17 EEB06453.1 - 7.4 6.7 8.3 7 6.7 3.9 2.3 2 0 0 2 2 2 0 DDHD domain Mei5 PF10376.9 EEB06454.1 - 2.7e-05 24.2 0.0 2.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Double-strand recombination repair protein AT_hook PF02178.19 EEB06454.1 - 3.8 7.7 38.8 0.076 12.9 5.1 4.6 4 0 0 4 4 4 0 AT hook motif TPR_1 PF00515.28 EEB06455.1 - 4.1e-26 89.7 1.4 3.3e-10 39.3 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06455.1 - 1.1e-20 71.9 7.5 1.9e-08 33.8 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEB06455.1 - 6.1e-17 61.0 9.0 2.9e-08 33.3 0.4 3.6 2 1 2 4 4 3 3 TPR repeat TPR_8 PF13181.6 EEB06455.1 - 6.7e-17 60.2 9.5 5.6e-08 32.4 0.2 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 EEB06455.1 - 1.1e-16 60.3 1.2 2.7e-16 59.1 1.2 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_17 PF13431.6 EEB06455.1 - 3.6e-12 45.8 2.6 0.001 19.3 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06455.1 - 1.1e-11 44.5 3.5 3e-05 24.5 0.0 4.2 2 2 3 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06455.1 - 6.4e-11 41.5 1.5 0.015 15.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06455.1 - 1.4e-10 41.3 8.0 2.7e-09 37.2 0.2 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06455.1 - 2.6e-09 37.4 0.3 4.7e-06 27.0 0.4 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06455.1 - 2.9e-09 37.4 0.8 0.00093 19.8 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEB06455.1 - 4e-07 29.7 1.8 0.021 14.7 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB06455.1 - 4.5e-07 29.9 0.3 0.0021 18.2 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEB06455.1 - 5.3e-06 25.8 0.3 1.5e-05 24.3 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB06455.1 - 1.1e-05 25.6 8.5 1.5e-05 25.1 0.7 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EEB06455.1 - 2.2e-05 24.9 5.6 3.2e-05 24.4 0.2 2.6 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 EEB06455.1 - 2.3e-05 24.7 1.1 0.65 10.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4919 PF16266.5 EEB06455.1 - 0.0091 16.0 1.4 0.022 14.7 0.2 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4919) GHBP PF12772.7 EEB06455.1 - 0.014 14.9 0.6 0.025 14.1 0.1 1.6 1 1 0 2 2 2 0 Growth hormone receptor binding TPR_3 PF07720.12 EEB06455.1 - 0.015 15.2 0.9 1.8 8.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ferritin_2 PF13668.6 EEB06455.1 - 0.052 13.7 3.0 0.15 12.2 3.0 1.8 1 0 0 1 1 1 0 Ferritin-like domain TPR_4 PF07721.14 EEB06455.1 - 0.12 13.1 0.0 16 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DapB_C PF05173.14 EEB06455.1 - 0.21 11.6 3.4 0.13 12.3 1.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, C-terminus GerD PF17898.1 EEB06455.1 - 0.22 11.5 3.5 1.8 8.6 0.2 2.6 1 1 1 2 2 2 0 Spore germination GerD central core domain MIT PF04212.18 EEB06455.1 - 0.4 10.8 12.3 0.65 10.1 1.1 3.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 EEB06455.1 - 2.8 8.1 7.4 9.4 6.4 0.5 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.14 EEB06456.1 - 6.6e-73 245.8 2.0 6.6e-73 245.8 2.0 1.9 2 0 0 2 2 2 1 Transcriptional repressor TCF25 MATH PF00917.26 EEB06456.1 - 0.11 12.6 2.1 0.18 12.0 0.7 2.0 2 0 0 2 2 2 0 MATH domain HrpB4 PF09502.10 EEB06456.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) Presenilin PF01080.17 EEB06456.1 - 4.8 5.8 6.4 1.1 7.9 2.3 2.0 2 0 0 2 2 2 0 Presenilin zf-CCHC PF00098.23 EEB06457.2 - 1.6e-10 40.6 21.4 0.002 18.1 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 EEB06457.2 - 0.0004 20.1 22.2 0.0086 15.9 0.3 4.3 4 0 0 4 4 4 3 Zinc knuckle DUF4177 PF13783.6 EEB06457.2 - 0.18 12.1 0.1 0.41 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) zf-CCHC_4 PF14392.6 EEB06457.2 - 0.85 9.4 22.0 2.5 7.9 0.3 4.2 4 0 0 4 4 4 0 Zinc knuckle zinc-ribbons_6 PF07191.12 EEB06457.2 - 4.1 7.5 14.8 4.8 7.2 4.9 2.5 1 1 1 2 2 2 0 zinc-ribbons TRAF6_Z2 PF18048.1 EEB06457.2 - 5.3 7.2 7.2 1.6 8.9 0.2 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DEAD PF00270.29 EEB06458.1 - 1.4e-13 51.0 0.0 2.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEB06458.1 - 1.4e-10 41.4 0.0 1.4e-10 41.4 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB06458.1 - 2.5e-08 34.2 0.1 7.9e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EEB06458.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CTP_transf_like PF01467.26 EEB06459.1 - 0.00034 20.8 0.0 0.00077 19.7 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1_ass PF16581.5 EEB06459.1 - 0.00037 20.5 0.1 0.00074 19.6 0.0 1.5 2 0 0 2 2 2 1 Cytidyltransferase-related C-terminal region Citrate_ly_lig PF08218.11 EEB06459.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Citrate lyase ligase C-terminal domain HIGH_NTase1 PF05636.11 EEB06459.1 - 0.051 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase UPF0160 PF03690.13 EEB06460.2 - 2.6e-123 411.7 0.0 3e-123 411.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF641 PF04859.12 EEB06461.1 - 0.00074 19.8 0.5 0.0018 18.6 0.5 1.7 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Bap31_Bap29_C PF18035.1 EEB06461.1 - 0.0055 16.7 1.6 0.0055 16.7 1.6 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain HMMR_N PF15905.5 EEB06461.1 - 0.012 15.2 2.5 0.016 14.7 0.4 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PKcGMP_CC PF16808.5 EEB06461.1 - 0.026 14.3 6.3 0.061 13.2 4.8 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GrpE PF01025.19 EEB06461.1 - 0.05 13.3 2.3 0.062 13.0 0.4 1.9 2 0 0 2 2 2 0 GrpE IL31 PF15209.6 EEB06461.1 - 0.069 12.9 0.9 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 Interleukin 31 RPW8 PF05659.11 EEB06461.1 - 0.092 12.4 0.6 0.64 9.7 0.1 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ATP12 PF07542.11 EEB06462.1 - 3.2e-25 88.7 0.0 6.6e-25 87.7 0.0 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein DUF572 PF04502.13 EEB06463.1 - 2.9e-67 227.6 6.7 3.4e-67 227.4 6.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF2396 PF09654.10 EEB06463.1 - 0.045 13.8 1.1 0.36 10.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) zf-FCS PF06467.14 EEB06463.1 - 0.047 13.6 1.2 0.58 10.2 0.5 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF4542 PF15075.6 EEB06463.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) DUF3449 PF11931.8 EEB06463.1 - 0.31 10.8 7.1 0.59 9.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Gpr1_Fun34_YaaH PF01184.19 EEB06464.1 - 2.5e-80 269.0 20.4 3e-80 268.7 20.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TMEM191C PF15194.6 EEB06464.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.2 3 0 0 3 3 3 0 TMEM191C family DUF2393 PF09624.10 EEB06464.1 - 2.2 8.3 4.3 5 7.1 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) UPF0300 PF08594.10 EEB06465.1 - 2e-45 154.7 0.0 3.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Mannosyl_trans3 PF11051.8 EEB06465.1 - 0.098 12.0 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative zf-RING_2 PF13639.6 EEB06466.2 - 8.1e-12 45.3 9.3 1.3e-11 44.6 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEB06466.2 - 7.1e-11 41.7 6.2 1.3e-10 40.8 6.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EEB06466.2 - 1.2e-08 35.1 6.4 2e-08 34.4 6.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEB06466.2 - 6.3e-08 32.3 9.2 1.3e-07 31.3 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB06466.2 - 2.3e-06 27.4 8.2 4e-06 26.6 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEB06466.2 - 3.7e-06 26.7 6.0 6.3e-06 26.0 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EEB06466.2 - 1.8e-05 24.5 2.3 1.8e-05 24.5 2.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EEB06466.2 - 2.5e-05 24.1 7.2 4.1e-05 23.5 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 EEB06466.2 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 EEB06466.2 - 0.0011 19.0 11.5 0.0012 18.9 10.2 1.8 2 0 0 2 2 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EEB06466.2 - 0.0014 18.2 4.6 0.0014 18.2 4.6 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 EEB06466.2 - 0.0032 17.3 4.8 0.0057 16.5 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 EEB06466.2 - 0.028 14.5 8.5 0.19 11.8 8.7 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3927 PF13064.6 EEB06466.2 - 0.049 13.6 0.4 0.1 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) Prok-RING_4 PF14447.6 EEB06466.2 - 0.072 13.0 7.5 0.13 12.1 7.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 EEB06466.2 - 0.091 12.9 2.3 0.15 12.2 2.3 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 EEB06466.2 - 0.097 12.9 7.1 0.66 10.2 7.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EEB06466.2 - 1.8 8.8 8.8 4.8 7.4 8.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EEB06466.2 - 2.1 8.7 6.7 3.6 8.0 6.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EEB06466.2 - 2.6 7.9 6.8 5.9 6.8 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Adaptin_N PF01602.20 EEB06467.1 - 6e-117 391.4 1.0 8e-117 390.9 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EEB06467.1 - 1.8e-46 158.0 6.9 4e-46 156.9 6.9 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EEB06467.1 - 3.9e-30 104.3 0.0 8.7e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EEB06467.1 - 3.4e-17 62.6 0.6 3e-08 33.9 0.1 4.9 4 0 0 4 4 4 4 HEAT repeats Cnd1 PF12717.7 EEB06467.1 - 1.5e-07 31.6 2.7 0.0078 16.3 0.3 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEB06467.1 - 0.0048 17.1 0.6 15 6.2 0.1 4.8 6 0 0 6 6 6 1 HEAT repeat Coatomer_b_Cpla PF14806.6 EEB06467.1 - 0.024 14.6 0.0 0.1 12.6 0.0 2.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform CLASP_N PF12348.8 EEB06467.1 - 0.028 14.0 1.1 0.75 9.3 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal Raptor_N PF14538.6 EEB06468.2 - 1.7e-65 219.4 0.0 3.2e-65 218.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 EEB06468.2 - 1.6e-06 27.9 1.3 0.1 12.9 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat WD40 PF00400.32 EEB06468.2 - 6.5e-05 23.6 8.9 7.2 7.7 0.0 7.1 8 0 0 8 8 8 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06468.2 - 0.00024 21.4 0.1 2.8 8.3 0.0 4.2 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 EEB06468.2 - 0.00027 21.0 0.0 0.0095 16.0 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HSP70 PF00012.20 EEB06469.1 - 1.9e-64 217.9 3.4 1.2e-63 215.3 1.4 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EEB06469.1 - 0.00015 20.7 0.2 0.00025 20.0 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EEB06469.1 - 0.0079 15.3 0.0 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; zinc_ribbon_2 PF13240.6 EEB06470.2 - 0.01 15.5 4.8 0.01 15.5 4.8 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EEB06470.2 - 0.012 15.6 2.9 0.014 15.4 1.3 1.9 2 0 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.22 EEB06470.2 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0128 PF03673.13 EEB06470.2 - 0.077 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) zf-C2H2 PF00096.26 EEB06470.2 - 0.085 13.4 0.2 0.085 13.4 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF35_N PF12172.8 EEB06470.2 - 0.6 10.0 6.6 0.55 10.2 4.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF629 PF04780.12 EEB06470.2 - 0.99 7.9 5.3 0.24 9.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-RanBP PF00641.18 EEB06470.2 - 4.2 6.8 7.9 0.39 10.1 2.8 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ribosomal_S8 PF00410.19 EEB06471.1 - 1.1e-22 80.3 0.3 1.8e-22 79.6 0.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Sds3 PF08598.11 EEB06472.1 - 0.38 10.7 12.3 0.21 11.6 10.6 1.5 1 1 0 1 1 1 0 Sds3-like Mem_trans PF03547.18 EEB06473.2 - 3.2e-67 226.6 1.2 3.8e-67 226.4 1.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Chlor_dismutase PF06778.12 EEB06474.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlorite dismutase NTP_transferase PF00483.23 EEB06474.1 - 0.15 11.6 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase GPP34 PF05719.11 EEB06475.1 - 5.7e-65 219.2 0.0 7.3e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ECSIT PF06239.11 EEB06476.1 - 0.063 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway PCRF PF03462.18 EEB06477.2 - 1.4e-45 155.6 2.0 1.4e-45 155.5 0.2 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EEB06477.2 - 3.1e-33 114.1 4.9 3.1e-33 114.1 4.9 1.8 2 0 0 2 2 2 1 RF-1 domain Terminase_4 PF05119.12 EEB06477.2 - 0.01 16.2 0.1 0.033 14.6 0.1 1.9 1 0 0 1 1 1 0 Phage terminase, small subunit ApoC-I PF04691.12 EEB06477.2 - 0.092 12.7 2.3 8.6 6.4 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) PX PF00787.24 EEB06478.2 - 3.1e-17 62.6 1.1 7.5e-17 61.3 1.1 1.7 1 0 0 1 1 1 1 PX domain PLDc PF00614.22 EEB06478.2 - 1.3e-15 56.8 1.8 3.5e-07 30.1 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EEB06478.2 - 1.1e-10 41.5 0.1 6e-06 26.2 0.0 3.2 2 1 0 2 2 2 2 PLD-like domain MRP-S28 PF10213.9 EEB06479.2 - 1.4e-21 77.2 0.1 2.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF573 PF04504.14 EEB06479.2 - 0.051 14.2 0.3 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 ECR1_N PF14382.6 EEB06480.1 - 2.6e-17 62.3 0.3 4.5e-17 61.6 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EEB06480.1 - 3.9e-09 36.7 0.1 8.6e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EEB06480.1 - 0.027 15.1 0.1 0.11 13.1 0.1 2.0 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 S1 PF00575.23 EEB06480.1 - 0.067 13.5 0.1 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 S1 RNA binding domain tRNA-synt_1b PF00579.25 EEB06481.1 - 1.9e-27 96.4 0.0 5.8e-27 94.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TFIIB PF00382.19 EEB06482.1 - 5.3e-44 148.1 0.5 1e-24 86.4 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EEB06482.1 - 2.6e-12 46.0 2.0 4.2e-12 45.4 2.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 EEB06482.1 - 0.0068 16.4 0.5 0.011 15.8 0.1 1.6 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 EEB06482.1 - 0.016 14.9 0.2 0.054 13.2 0.1 1.8 1 1 1 2 2 2 0 Cyclin, N-terminal domain HTH_5 PF01022.20 EEB06482.1 - 0.028 14.3 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Cyclin_C PF02984.19 EEB06482.1 - 0.04 14.0 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4_2 PF08281.12 EEB06482.1 - 0.069 12.8 0.3 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 zf-ribbon_3 PF13248.6 EEB06482.1 - 0.077 12.4 1.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain TFIIB_C_1 PF18542.1 EEB06482.1 - 0.13 12.3 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 MerR PF00376.23 EEB06482.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein CoA_binding PF02629.19 EEB06483.1 - 5.5e-27 94.3 2.8 7.3e-27 93.9 1.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EEB06483.1 - 1.9e-24 86.2 0.0 4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 EEB06483.1 - 1.5e-06 28.7 0.0 8.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EEB06483.1 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 EEB06483.1 - 0.076 13.9 0.1 0.18 12.6 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SusD-like_2 PF12771.7 EEB06484.2 - 0.089 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane TBCC PF07986.12 EEB06485.1 - 5.6e-08 32.5 0.9 1.3e-07 31.3 0.9 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EEB06485.1 - 1.1e-05 25.9 0.5 2.3e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF2370 PF10176.9 EEB06486.2 - 5.2e-39 134.2 0.7 6.4e-38 130.7 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) RPT PF13446.6 EEB06487.1 - 2.8e-51 171.3 7.7 5.9e-17 61.3 0.5 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 EEB06487.1 - 2.5e-45 155.0 1.1 4.1e-45 154.3 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB06487.1 - 1e-08 35.2 0.9 4.9e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase End_N_terminal PF12218.8 EEB06487.1 - 0.033 13.9 0.8 0.11 12.3 0.0 2.3 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Siah-Interact_N PF09032.11 EEB06487.1 - 0.11 12.8 0.3 0.54 10.6 0.3 2.2 1 0 0 1 1 1 0 Siah interacting protein, N terminal RRM_1 PF00076.22 EEB06488.2 - 8e-54 179.4 0.0 3.9e-17 61.8 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB06488.2 - 0.00014 21.9 0.0 3.6 7.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif Limkain-b1 PF11608.8 EEB06488.2 - 0.0027 17.7 0.2 0.27 11.3 0.0 3.3 3 1 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 EEB06488.2 - 0.01 15.4 0.0 14 5.3 0.0 3.2 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 EEB06488.2 - 0.021 14.3 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) RRM_Rrp7 PF17799.1 EEB06488.2 - 0.083 12.7 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain AAA PF00004.29 EEB06489.1 - 2.2e-38 131.7 0.0 3.6e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEB06489.1 - 3e-07 30.3 0.0 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EEB06489.1 - 1.4e-05 24.8 0.1 2.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EEB06489.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB06489.1 - 2.8e-05 24.4 0.3 0.002 18.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EEB06489.1 - 0.00053 20.0 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB06489.1 - 0.00071 20.0 2.1 0.0014 19.0 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.13 EEB06489.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EEB06489.1 - 0.0017 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EEB06489.1 - 0.0035 17.1 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB06489.1 - 0.004 16.6 0.1 0.0089 15.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EEB06489.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEB06489.1 - 0.0089 16.2 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEB06489.1 - 0.011 16.3 0.0 0.039 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEB06489.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB06489.1 - 0.028 14.0 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EEB06489.1 - 0.036 13.5 0.0 4 6.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EEB06489.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEB06489.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB06489.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 EEB06489.1 - 0.11 12.2 1.2 0.69 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EEB06489.1 - 0.13 12.6 0.0 0.67 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EEB06489.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EEB06489.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EEB06489.1 - 1.4 9.1 3.3 1 9.6 0.1 2.3 3 0 0 3 3 2 0 AAA domain Glyco_transf_20 PF00982.21 EEB06490.2 - 1.1e-202 673.9 0.0 1.3e-202 673.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EEB06490.2 - 0.033 13.9 0.1 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EEB06490.2 - 0.046 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 HSF_DNA-bind PF00447.17 EEB06491.2 - 3.9e-29 101.1 2.1 8.9e-29 100.0 2.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EEB06491.2 - 0.0049 17.3 0.2 0.025 15.0 0.0 2.2 2 0 0 2 2 2 1 Ets-domain DUF1759 PF03564.15 EEB06491.2 - 0.0066 16.4 0.2 0.015 15.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) IBR PF01485.21 EEB06492.2 - 3.6e-21 75.1 48.0 3.2e-11 43.3 7.1 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EEB06492.2 - 3.7e-05 23.5 4.1 3.7e-05 23.5 4.1 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB06492.2 - 0.0024 18.2 4.2 0.0024 18.2 4.2 4.4 3 2 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EEB06492.2 - 0.0039 17.0 4.9 0.0039 17.0 4.9 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB06492.2 - 0.0082 16.2 3.4 0.0082 16.2 3.4 4.6 5 1 0 5 5 5 1 RING-type zinc-finger DUF1488 PF07369.11 EEB06492.2 - 0.48 10.4 3.5 1.2 9.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Xpo1 PF08389.12 EEB06493.1 - 1.1e-13 51.5 1.7 1.1e-13 51.5 1.7 3.2 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EEB06493.1 - 0.00046 20.0 0.7 0.0042 17.0 0.1 3.0 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 EEB06493.1 - 0.052 13.6 0.1 0.052 13.6 0.1 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-CCCH_4 PF18044.1 EEB06494.1 - 4.3e-13 48.7 9.2 2.5e-06 27.1 1.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EEB06494.1 - 1.5e-09 37.5 8.8 0.00019 21.2 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEB06494.1 - 5e-09 35.9 18.5 0.00014 21.8 4.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EEB06494.1 - 1.6e-08 35.2 6.1 0.00045 20.9 0.6 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EEB06494.1 - 1.9e-06 28.1 1.0 3.1e-06 27.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger containing family eIF_4EBP PF05456.11 EEB06494.1 - 0.00097 19.1 0.5 0.00097 19.1 0.5 2.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) zf-CCCH_2 PF14608.6 EEB06494.1 - 0.0091 16.4 14.0 0.047 14.2 3.4 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_5 PF18384.1 EEB06494.1 - 3.7 7.7 4.8 28 4.9 1.5 2.3 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) Methyltransf_16 PF10294.9 EEB06495.2 - 7.6e-21 74.6 0.1 1.1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EEB06495.2 - 1.4e-06 27.9 0.1 1.9e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EEB06495.2 - 0.00019 21.0 0.1 0.00032 20.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EEB06495.2 - 0.00076 20.1 0.1 0.0014 19.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EEB06495.2 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 EEB06495.2 - 0.028 15.2 0.1 0.049 14.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EEB06495.2 - 0.073 13.7 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Seipin PF06775.14 EEB06496.2 - 4.6e-42 144.4 3.8 5.7e-42 144.1 3.8 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Palm_thioest PF02089.15 EEB06496.2 - 0.054 13.3 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase EF-hand_8 PF13833.6 EEB06497.1 - 0.028 14.2 1.4 0.053 13.4 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EEB06497.1 - 0.042 13.8 0.7 0.37 10.9 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EEB06497.1 - 0.08 12.5 2.7 0.46 10.1 0.9 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EEB06497.1 - 0.57 10.7 7.8 0.18 12.3 1.7 3.3 3 1 0 3 3 3 0 EF-hand domain pair CASP_C PF08172.12 EEB06497.1 - 1.7 7.9 31.2 0.4 10.0 9.8 3.9 2 1 0 3 3 3 0 CASP C terminal MSV199 PF10553.9 EEB06497.1 - 2.8 8.2 6.9 2.7 8.3 0.0 3.0 2 1 1 3 3 3 0 MSV199 domain Tropomyosin PF00261.20 EEB06497.1 - 4.1 6.7 41.2 0.096 12.0 23.0 3.1 3 0 0 3 3 3 0 Tropomyosin ATG16 PF08614.11 EEB06497.1 - 8.7 6.5 51.5 0.033 14.4 21.1 3.7 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Pyr_redox_2 PF07992.14 EEB06498.1 - 1.9e-52 178.3 0.0 2.4e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEB06498.1 - 3.7e-10 40.2 0.0 2e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DR2241 PF18069.1 EEB06498.1 - 0.096 12.6 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 DR2241 stabilising domain NAD_binding_7 PF13241.6 EEB06498.1 - 0.15 12.5 0.0 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Cullin PF00888.22 EEB06499.1 - 1.9e-137 459.5 6.4 3e-137 458.9 6.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEB06499.1 - 1.4e-22 79.4 0.7 7e-22 77.2 0.7 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain Na_H_Exchanger PF00999.21 EEB06500.2 - 2.9e-81 273.2 27.7 3.4e-81 273.0 27.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 EEB06500.2 - 1.9e-06 27.4 25.6 0.00022 20.6 13.7 2.2 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.6 EEB06500.2 - 0.028 14.2 0.3 0.028 14.2 0.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Peptidase_M19 PF01244.21 EEB06501.1 - 9e-104 347.1 0.0 1.1e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Aldo_ket_red PF00248.21 EEB06502.1 - 5.4e-69 232.6 0.0 6.3e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 EEB06503.1 - 2.8e-41 141.0 0.2 8.6e-41 139.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEB06503.1 - 3.7e-19 68.4 0.0 7.3e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EEB06503.1 - 5.4e-12 45.3 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EEB06503.1 - 1.8e-05 24.7 0.1 0.00012 22.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB06503.1 - 2.8e-05 24.6 1.2 0.017 15.5 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EEB06503.1 - 3.4e-05 24.0 0.0 9.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEB06503.1 - 0.00086 19.1 0.0 0.0024 17.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB06503.1 - 0.0009 19.5 1.4 0.099 12.9 0.0 3.0 2 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EEB06503.1 - 0.0028 17.5 0.6 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEB06503.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EEB06503.1 - 0.016 14.6 0.1 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EEB06503.1 - 0.018 14.5 0.1 0.065 12.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_S19 PF00203.21 EEB06503.1 - 0.019 14.8 0.1 11 6.0 0.0 2.9 3 1 0 3 3 3 0 Ribosomal protein S19 DUF815 PF05673.13 EEB06503.1 - 0.031 13.4 0.0 0.057 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EEB06503.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EEB06503.1 - 0.075 12.7 0.3 0.34 10.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain GrpE PF01025.19 EEB06503.1 - 0.48 10.1 9.5 0.36 10.5 6.9 2.1 2 0 0 2 2 2 0 GrpE AAA_19 PF13245.6 EEB06503.1 - 0.74 10.1 3.3 5.8 7.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 EEB06503.1 - 3 8.1 12.3 1.6 9.0 8.2 2.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 EEB06504.1 - 6.8e-22 77.4 9.2 7.5e-22 77.3 9.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Bacillus_HBL PF05791.11 EEB06504.1 - 0.016 15.1 5.1 0.46 10.3 0.3 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Occludin_ELL PF07303.13 EEB06504.1 - 0.021 15.5 0.6 0.034 14.9 0.6 1.4 1 0 0 1 1 1 0 Occludin homology domain FTA4 PF13093.6 EEB06504.1 - 0.022 14.6 3.9 0.026 14.4 3.9 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.17 EEB06504.1 - 0.067 13.1 7.0 0.14 12.1 1.7 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF1192 PF06698.11 EEB06504.1 - 0.085 12.9 1.2 7.3 6.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF2175 PF09943.9 EEB06504.1 - 0.096 13.0 2.1 0.19 12.0 1.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) ERp29 PF07749.12 EEB06504.1 - 0.15 13.0 2.2 0.83 10.6 2.2 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain APG6_N PF17675.1 EEB06504.1 - 0.32 11.5 6.5 0.46 11.0 6.5 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 EEB06504.1 - 0.94 9.7 6.8 5.3 7.2 1.3 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 EEB06504.1 - 2.2 8.5 7.2 4.9 7.5 1.3 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Kinesin PF00225.23 EEB06505.1 - 1.5e-102 343.0 0.8 1.5e-102 343.0 0.8 2.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEB06505.1 - 3.1e-56 189.4 2.0 1.2e-55 187.6 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding Muted PF14942.6 EEB06505.1 - 0.0075 16.6 6.1 0.0075 16.6 6.1 4.7 3 2 2 5 5 5 1 Organelle biogenesis, Muted-like protein GAS PF13851.6 EEB06505.1 - 0.014 14.8 43.8 0.68 9.2 15.6 4.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_24 PF13479.6 EEB06505.1 - 0.06 13.1 2.9 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEB06505.1 - 0.08 13.3 0.2 0.08 13.3 0.2 2.7 3 0 0 3 3 3 0 AAA ATPase domain Keratin_2_head PF16208.5 EEB06505.1 - 0.16 12.1 0.3 0.39 10.8 0.3 1.6 1 0 0 1 1 1 0 Keratin type II head AAR2 PF05282.11 EEB06506.1 - 1.4e-29 103.6 2.6 2e-28 99.9 2.6 2.1 1 1 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.19 EEB06507.1 - 2e-47 160.2 2.4 2.4e-47 159.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EEB06507.1 - 0.084 13.1 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DNA_pol_B PF00136.21 EEB06508.2 - 1.7e-122 409.5 1.1 2.4e-122 409.0 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEB06508.2 - 1e-37 130.1 0.0 1.9e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 EEB06508.2 - 3.3e-33 115.0 5.2 1.4e-31 109.7 3.6 2.4 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 EEB06508.2 - 6.2e-24 83.9 5.6 1.8e-23 82.4 5.6 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EEB06508.2 - 0.0041 16.1 0.0 0.0089 14.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral CAP_assoc_N PF14504.6 EEB06508.2 - 0.033 13.9 0.2 0.07 12.9 0.2 1.5 1 0 0 1 1 1 0 CAP-associated N-terminal Ribosomal_L25p PF01386.19 EEB06508.2 - 0.12 12.9 0.5 4.1 8.0 0.0 3.4 3 0 0 3 3 3 0 Ribosomal L25p family Ribosomal_L30_N PF08079.12 EEB06509.1 - 1.7e-23 82.7 16.7 3.6e-23 81.6 16.7 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EEB06509.1 - 3.1e-19 68.6 1.0 6.3e-19 67.6 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-C2H2 PF00096.26 EEB06511.1 - 0.047 14.2 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fes1 PF08609.10 EEB06513.1 - 3.8e-22 79.0 2.6 3.8e-22 79.0 2.6 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EEB06513.1 - 0.00032 21.0 0.6 0.013 15.9 0.1 3.0 1 1 2 3 3 3 2 HEAT repeats SIL1 PF16782.5 EEB06513.1 - 0.00033 20.0 1.1 0.00043 19.6 1.1 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Arm PF00514.23 EEB06513.1 - 0.0019 18.2 0.5 0.65 10.1 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EEB06513.1 - 0.0066 16.5 0.4 1.7 8.7 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEB06513.1 - 0.059 13.9 0.4 0.56 10.8 0.1 2.3 1 1 1 2 2 2 0 HEAT-like repeat HEAT PF02985.22 EEB06513.1 - 0.064 13.6 0.0 0.36 11.2 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat DUF3361 PF11841.8 EEB06513.1 - 0.079 12.9 2.0 5.3 7.0 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) G-patch_2 PF12656.7 EEB06514.1 - 2.3e-18 66.0 2.8 3e-18 65.6 0.2 2.7 2 0 0 2 2 2 1 G-patch domain RAB3GAP2_N PF14655.6 EEB06514.1 - 0.083 12.1 2.1 0.13 11.5 2.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CytadhesinP1 PF12378.8 EEB06514.1 - 0.099 12.8 2.3 2.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein SRP54 PF00448.22 EEB06515.2 - 1.5e-39 135.7 0.6 3.5e-39 134.5 0.3 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EEB06515.2 - 3.7e-07 30.4 4.4 6.5e-07 29.6 4.4 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EEB06515.2 - 0.00033 20.8 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain Drc1-Sld2 PF11719.8 EEB06515.2 - 0.0079 15.8 3.2 0.011 15.3 3.2 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein ArsA_ATPase PF02374.15 EEB06515.2 - 0.039 13.2 0.4 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Anion-transporting ATPase zf-CCCH_4 PF18044.1 EEB06515.2 - 0.3 10.9 1.4 0.5 10.2 1.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CHY PF05495.12 EEB06517.1 - 4.1e-12 46.4 15.4 7.2e-12 45.6 15.4 1.4 1 0 0 1 1 1 1 CHY zinc finger ADD_ATRX PF17981.1 EEB06517.1 - 0.005 16.7 2.8 0.011 15.6 2.8 1.6 1 0 0 1 1 1 1 Cysteine Rich ADD domain zinc_ribbon_10 PF10058.9 EEB06517.1 - 0.021 14.6 0.9 0.021 14.6 0.9 2.0 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3797 PF12677.7 EEB06517.1 - 0.041 13.8 1.3 0.49 10.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Zn_ribbon_SprT PF17283.2 EEB06517.1 - 0.089 12.7 0.4 0.089 12.7 0.4 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Cys_rich_KTR PF14205.6 EEB06517.1 - 0.2 11.5 6.0 2.8 7.8 2.0 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR Trm112p PF03966.16 EEB06517.1 - 0.27 11.8 2.5 5.7 7.6 0.4 2.6 2 1 0 2 2 2 0 Trm112p-like protein HypA PF01155.19 EEB06517.1 - 1.1 9.4 7.8 3.8 7.6 7.8 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EEB06517.1 - 3.7 7.4 11.3 1.5 8.7 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EEB06517.1 - 4.9 7.4 11.4 4.6 7.4 7.5 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Autophagy_N PF03986.13 EEB06518.1 - 7.5e-35 119.9 1.2 1e-34 119.4 1.2 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EEB06518.1 - 8.5e-18 64.7 0.2 1.9e-17 63.6 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EEB06518.1 - 4.7e-10 38.8 4.5 1.4e-09 37.2 4.5 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF2382 PF09557.10 EEB06518.1 - 0.22 11.8 1.1 0.41 10.9 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2382) Astro_capsid_p PF12226.8 EEB06518.1 - 0.52 9.4 6.9 0.74 8.9 6.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 EEB06518.1 - 2.1 8.0 6.0 2.9 7.6 6.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EEB06518.1 - 3 7.1 7.3 4.2 6.6 7.3 1.1 1 0 0 1 1 1 0 NOA36 protein RPA43_OB PF17875.1 EEB06519.1 - 1e-17 64.9 0.1 1.1e-15 58.3 0.1 2.1 1 1 1 2 2 2 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EEB06519.1 - 1.6e-09 38.0 0.0 4e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 WD40 PF00400.32 EEB06520.1 - 3.8e-28 97.2 10.9 7.7e-07 29.7 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06520.1 - 2.6e-06 27.6 0.2 0.01 16.1 0.0 4.6 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EEB06520.1 - 0.00064 19.7 0.4 3.1 7.9 0.0 4.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EEB06520.1 - 0.016 14.2 0.1 0.45 9.4 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEB06520.1 - 0.023 14.0 0.0 1.3 8.3 0.0 3.3 3 1 1 4 4 4 0 WD40-like domain Zn_Tnp_IS1595 PF12760.7 EEB06520.1 - 0.16 11.9 3.8 0.42 10.6 3.8 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Apt1 PF10351.9 EEB06521.1 - 2e-124 416.1 6.0 2e-124 416.1 6.0 2.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EEB06521.1 - 4.6e-124 414.9 14.5 1.7e-123 413.1 14.5 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EEB06521.1 - 3.5e-47 160.4 0.0 8.5e-47 159.2 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EEB06521.1 - 1.3e-36 125.8 1.0 1.3e-36 125.8 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27 PF10344.9 EEB06521.1 - 4.1e-29 101.3 25.7 2e-27 95.7 19.1 3.4 3 0 0 3 3 3 2 Mitochondrial protein from FMP27 Fmp27_SW PF10305.9 EEB06521.1 - 6.2e-27 94.3 0.4 3.7e-26 91.8 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L32e PF01655.18 EEB06522.1 - 1.2e-46 157.5 0.7 1.5e-46 157.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 NAD_kinase PF01513.21 EEB06523.1 - 2.6e-69 233.7 0.0 3.1e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EEB06523.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Nexin_C PF08628.12 EEB06523.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Sorting nexin C terminal DUF4598 PF15370.6 EEB06524.1 - 2.5e-12 47.2 7.4 4.4e-12 46.4 7.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Ribosomal_L5e PF17144.4 EEB06525.2 - 3.8e-102 339.2 6.4 4.3e-58 195.9 7.4 3.3 2 1 0 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EEB06525.2 - 8.7e-50 167.6 18.6 1.1e-32 112.8 5.0 2.6 3 0 0 3 3 3 2 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 EEB06525.2 - 1.4e-05 25.2 1.1 0.48 10.7 0.0 3.6 2 2 0 2 2 2 2 Threonine synthase N terminus TetR_C_24 PF17932.1 EEB06525.2 - 0.006 16.8 0.1 5.1 7.4 0.0 2.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain K_oxygenase PF13434.6 EEB06525.2 - 0.022 13.9 0.8 1.1 8.3 0.4 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1727 PF08353.10 EEB06525.2 - 0.036 14.0 0.5 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) DUF5388 PF17363.2 EEB06525.2 - 0.069 13.4 0.3 27 5.1 0.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5388) DUF2034 PF10356.9 EEB06526.1 - 1.4e-26 93.1 0.0 8.3e-14 51.4 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EEB06526.1 - 1.7e-10 40.9 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease PGAP1 PF07819.13 EEB06527.2 - 2e-84 282.9 0.0 2.9e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EEB06527.2 - 0.00011 22.0 0.0 0.00028 20.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB06527.2 - 0.00018 22.2 0.1 0.00034 21.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEB06527.2 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EEB06527.2 - 0.03 13.9 0.1 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PI3_PI4_kinase PF00454.27 EEB06528.2 - 1.3e-39 136.5 0.0 3.6e-39 135.1 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-RING_5 PF14634.6 EEB06529.1 - 1.5e-05 24.8 6.1 2.6e-05 24.1 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EEB06529.1 - 0.0001 22.6 5.4 0.00016 21.9 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEB06529.1 - 0.00012 21.9 6.9 0.00029 20.6 6.9 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB06529.1 - 0.00017 21.6 2.7 0.00032 20.6 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEB06529.1 - 0.0008 19.2 6.4 0.0014 18.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EEB06529.1 - 0.0016 18.5 3.8 0.0029 17.7 3.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 EEB06529.1 - 0.0028 17.5 6.9 0.0059 16.4 6.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEB06529.1 - 0.031 14.1 5.7 1.2 9.1 5.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EEB06529.1 - 0.052 13.8 5.5 0.052 13.8 4.4 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 EEB06529.1 - 0.052 13.5 9.0 0.23 11.4 9.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-NADH-PPase PF09297.11 EEB06529.1 - 0.055 13.1 6.9 0.66 9.7 4.3 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 EEB06529.1 - 0.063 13.3 6.1 1.3 9.1 0.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EEB06529.1 - 0.096 12.7 4.0 0.17 11.9 4.0 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 EEB06529.1 - 0.096 12.5 4.0 0.18 11.7 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 EEB06529.1 - 0.19 11.2 8.1 4.5 6.8 3.6 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 EEB06529.1 - 0.32 11.3 3.2 0.57 10.5 3.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 EEB06529.1 - 0.39 10.0 2.9 0.49 9.7 2.2 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger Zn_ribbon_17 PF17120.5 EEB06529.1 - 0.46 10.1 7.0 1.2 8.8 6.9 1.7 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_2 PF13240.6 EEB06529.1 - 0.91 9.3 8.1 33 4.4 0.1 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.13 EEB06529.1 - 1.4 8.9 6.6 11 6.1 0.1 2.3 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_4 PF15227.6 EEB06529.1 - 3.3 8.0 7.2 14 6.0 7.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING WD40 PF00400.32 EEB06530.2 - 5.9e-11 42.7 18.2 0.023 15.6 0.4 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06530.2 - 2.1e-07 31.2 0.5 0.98 9.8 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB06530.2 - 0.00022 20.3 0.1 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Aconitase PF00330.20 EEB06531.1 - 1.1e-108 364.2 0.0 2.4e-107 359.8 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEB06531.1 - 4.6e-26 91.7 0.0 9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EEB06531.1 - 0.05 12.3 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) IPPT PF01715.17 EEB06532.2 - 1e-67 228.3 0.2 1.9e-67 227.4 0.1 1.4 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 EEB06532.2 - 2.9e-05 23.6 0.0 8.7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EEB06532.2 - 0.014 15.5 0.0 0.93 9.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EEB06532.2 - 0.021 14.8 0.1 0.098 12.6 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 EEB06532.2 - 0.099 13.2 0.3 1.7 9.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain IF-2B PF01008.17 EEB06533.1 - 5.6e-67 225.9 0.1 7.7e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family GatB_N PF02934.15 EEB06534.1 - 2e-91 306.2 0.0 2.4e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EEB06534.1 - 7e-21 74.7 0.1 1.4e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 GatB domain Ferritin_2 PF13668.6 EEB06535.1 - 9.7e-18 64.7 0.3 1.6e-17 64.0 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain Chromo_shadow PF01393.19 EEB06536.1 - 6.3e-14 51.8 0.1 2e-13 50.2 0.1 1.9 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EEB06536.1 - 8e-12 44.9 2.3 8e-12 44.9 2.3 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SR-25 PF10500.9 EEB06536.1 - 0.75 9.4 37.6 0.37 10.4 16.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L32e PF01655.18 EEB06537.2 - 3.7e-31 107.7 0.2 5.3e-31 107.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Las1 PF04031.13 EEB06538.1 - 1.6e-42 145.2 0.4 4.5e-42 143.8 0.0 2.0 2 0 0 2 2 2 1 Las1-like NAD_kinase PF01513.21 EEB06539.1 - 3.3e-83 279.3 0.0 4.1e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Nup_retrotrp_bd PF10599.9 EEB06539.1 - 0.21 12.3 2.1 0.32 11.7 0.5 2.1 2 0 0 2 2 2 0 Retro-transposon transporting motif zf-C2H2 PF00096.26 EEB06540.1 - 0.00035 20.8 0.6 0.00035 20.8 0.6 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EEB06540.1 - 0.00048 20.0 0.5 0.00098 19.1 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EEB06540.1 - 0.1 13.5 0.5 0.1 13.5 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RanBP PF00641.18 EEB06541.1 - 3.2e-07 29.6 4.1 6e-07 28.7 4.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LSM PF01423.22 EEB06542.1 - 2.4e-20 72.0 0.1 2.9e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEB06542.1 - 0.033 13.8 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Hfq protein UBX PF00789.20 EEB06543.1 - 8.9e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EEB06543.1 - 8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Jnk-SapK_ap_N PF09744.9 EEB06543.1 - 0.036 14.3 4.8 0.089 13.0 4.8 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4274 PF14096.6 EEB06543.1 - 7.4 6.6 6.3 4.5 7.3 0.7 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4274) SPRY PF00622.28 EEB06544.1 - 1.3e-13 51.1 0.2 3.2e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Response_reg PF00072.24 EEB06545.2 - 1.6e-19 70.1 1.6 1.5e-18 67.0 0.1 3.3 4 0 0 4 4 4 1 Response regulator receiver domain HisKA PF00512.25 EEB06545.2 - 9.7e-17 60.8 0.1 2.8e-16 59.3 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EEB06545.2 - 6.7e-14 52.6 0.0 1.6e-12 48.1 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 EEB06545.2 - 1.1e-11 45.2 0.0 4.4e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.25 EEB06545.2 - 6.7e-06 25.7 0.0 0.00029 20.3 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06545.2 - 4.6e-05 22.8 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_3 PF08447.12 EEB06545.2 - 0.00019 21.6 0.0 0.00075 19.7 0.0 2.0 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 EEB06545.2 - 0.0025 18.5 0.0 0.0058 17.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 EEB06545.2 - 0.0036 17.8 0.0 0.0074 16.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 EEB06545.2 - 0.012 15.9 0.0 0.53 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain GAF_3 PF13492.6 EEB06545.2 - 0.049 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 GAF domain DUF87 PF01935.17 EEB06545.2 - 0.071 13.2 0.1 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EEB06545.2 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase DUF4029 PF13221.6 EEB06545.2 - 0.19 12.4 1.7 0.68 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Ribosomal_L27e PF01777.18 EEB06546.1 - 1.1e-38 131.5 2.8 1.4e-38 131.1 2.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EEB06546.1 - 0.0004 20.2 1.0 0.00091 19.1 1.0 1.7 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.27 EEB06547.1 - 1.8e-31 107.9 10.1 1.4e-10 40.9 0.5 4.5 1 1 2 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB06547.1 - 0.035 13.3 2.7 0.19 10.9 0.1 2.6 1 1 1 3 3 3 0 Gammaproteobacterial serine protease Oxysterol_BP PF01237.18 EEB06548.2 - 1.3e-68 231.5 3.1 2.1e-66 224.3 3.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L17 PF01196.19 EEB06549.1 - 1.5e-31 109.2 0.0 3.1e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 ArgJ PF01960.18 EEB06550.1 - 1.6e-146 487.9 2.3 1.8e-146 487.7 2.3 1.0 1 0 0 1 1 1 1 ArgJ family zf-RING_2 PF13639.6 EEB06551.1 - 1.6e-13 50.7 4.8 1.6e-13 50.7 4.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EEB06551.1 - 1.4e-11 43.9 4.3 3.5e-11 42.6 2.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EEB06551.1 - 1.3e-08 34.6 8.6 8e-07 28.8 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB06551.1 - 1.7e-08 34.1 4.8 1.7e-08 34.1 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB06551.1 - 5e-07 29.6 10.9 3.6e-06 26.8 3.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 EEB06551.1 - 7.9e-07 29.3 2.7 7.9e-07 29.3 2.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEB06551.1 - 4.4e-06 26.6 2.8 4.4e-06 26.6 2.8 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEB06551.1 - 6e-06 26.0 4.1 6e-06 26.0 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_11 PF11682.8 EEB06551.1 - 0.00056 19.9 0.4 0.0013 18.7 0.4 1.6 1 0 0 1 1 1 1 Probable zinc-ribbon zf-ANAPC11 PF12861.7 EEB06551.1 - 0.0042 17.1 0.8 0.0042 17.1 0.8 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 EEB06551.1 - 0.015 15.5 5.3 0.061 13.6 5.3 2.1 1 1 0 1 1 1 0 zinc-ribbon Vps39_2 PF10367.9 EEB06551.1 - 0.023 15.1 1.7 0.031 14.7 0.4 1.9 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.6 EEB06551.1 - 0.026 14.4 13.0 0.034 14.1 6.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 EEB06551.1 - 0.046 13.6 10.2 0.039 13.8 3.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EEB06551.1 - 0.062 13.0 1.9 0.16 11.6 1.9 1.7 1 0 0 1 1 1 0 P-11 zinc finger RINGv PF12906.7 EEB06551.1 - 0.08 13.1 4.3 0.19 11.9 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zinc-ribbons_6 PF07191.12 EEB06551.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-C2H2_6 PF13912.6 EEB06551.1 - 0.23 11.5 0.1 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.19 EEB06551.1 - 0.48 10.5 6.5 0.13 12.2 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EEB06551.1 - 0.51 10.4 8.1 2.8 8.1 0.6 2.7 2 1 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 EEB06551.1 - 0.76 9.9 5.4 2.2 8.5 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EEB06551.1 - 3.6 7.3 10.8 0.062 12.9 3.4 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EEB06551.1 - 3.8 7.8 8.7 0.89 9.8 4.4 2.2 2 1 0 2 2 1 0 FANCL C-terminal domain Fis1_TPR_C PF14853.6 EEB06552.1 - 7.1e-10 38.8 0.1 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EEB06552.1 - 3e-05 24.4 0.2 6e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06552.1 - 0.0007 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06552.1 - 0.052 14.2 0.6 0.16 12.7 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06552.1 - 0.086 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06552.1 - 0.099 13.5 0.0 0.3 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat GDA1_CD39 PF01150.17 EEB06553.1 - 1.1e-106 357.1 0.0 1.4e-106 356.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2098 PF09871.9 EEB06553.1 - 0.068 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) HAGH_C PF16123.5 EEB06554.1 - 2.5e-18 66.4 0.8 4.4e-18 65.6 0.8 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EEB06554.1 - 3.7e-17 63.0 1.7 2.2e-15 57.2 1.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEB06554.1 - 4.5e-05 23.1 0.7 0.00094 18.7 0.7 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pam16 PF03656.13 EEB06555.1 - 2.9e-05 24.1 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EEB06555.1 - 0.00045 20.3 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Vps16_C PF04840.12 EEB06556.2 - 4.7e-101 338.0 9.2 7.5e-101 337.4 9.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EEB06556.2 - 6.4e-92 308.4 0.0 9.9e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region RPN6_N PF18055.1 EEB06556.2 - 0.063 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain WD40 PF00400.32 EEB06557.1 - 5.2e-12 46.1 8.3 0.00019 22.1 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06557.1 - 2.3e-05 24.6 0.0 1.8 8.9 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Helo_like_N PF17111.5 EEB06557.1 - 0.043 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins ArfGap PF01412.18 EEB06558.2 - 3.4e-41 140.0 1.3 5.6e-41 139.3 1.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Chromo_shadow PF01393.19 EEB06559.2 - 1.3e-20 73.2 2.6 6.5e-18 64.6 0.0 2.9 3 0 0 3 3 3 2 Chromo shadow domain Chromo PF00385.24 EEB06559.2 - 6e-13 48.5 3.2 6e-13 48.5 3.2 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_29 PF13551.6 EEB06559.2 - 1 9.5 3.5 0.59 10.2 0.9 2.0 2 0 0 2 2 2 0 Winged helix-turn helix DUF3295 PF11702.8 EEB06560.2 - 5.5e-10 39.2 40.5 1.8e-09 37.5 39.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EEB06560.2 - 1.7e-08 34.2 0.4 1.7e-08 34.2 0.4 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TRAUB PF08164.12 EEB06561.1 - 1.2e-30 105.8 0.5 1.2e-30 105.8 0.5 3.3 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EEB06561.1 - 1.6e-15 58.0 2.4 1.6e-15 58.0 2.4 3.4 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Rad9 PF04139.13 EEB06562.2 - 2.5e-66 223.7 0.5 3.1e-66 223.4 0.5 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EEB06562.2 - 0.0002 20.6 0.7 0.00031 19.9 0.7 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L30 PF00327.20 EEB06563.2 - 2.8e-12 46.3 0.5 2.8e-12 46.3 0.5 2.5 4 0 0 4 4 4 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 EEB06563.2 - 6e-11 42.4 15.7 6e-11 42.4 15.7 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain AP1AR PF15745.5 EEB06563.2 - 0.063 12.9 4.0 0.09 12.4 4.0 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Ribosomal_L13e PF01294.18 EEB06565.1 - 3.2e-78 261.7 3.0 4e-78 261.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sod_Fe_N PF00081.22 EEB06565.1 - 0.089 13.3 0.0 0.23 12.0 0.0 1.7 1 1 1 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain 3-HAO PF06052.12 EEB06565.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Ribosomal_S9 PF00380.19 EEB06566.1 - 9e-32 110.1 1.0 1e-31 110.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Paf1 PF03985.13 EEB06567.1 - 7.1e-84 282.2 0.0 8.7e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Paf1 Actin PF00022.19 EEB06568.1 - 6.7e-30 104.0 0.0 9.7e-29 100.2 0.0 2.5 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EEB06568.1 - 6e-08 32.3 0.3 0.0037 16.5 0.0 2.8 3 0 0 3 3 3 2 Putative actin-like family MreB_Mbl PF06723.13 EEB06568.1 - 0.0019 17.1 0.0 0.17 10.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EEB06568.1 - 0.087 13.3 0.0 0.35 11.3 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA G_glu_transpept PF01019.21 EEB06569.1 - 4.7e-174 579.9 0.0 5.6e-174 579.7 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Kinesin PF00225.23 EEB06570.2 - 1.1e-104 350.0 0.7 1.1e-104 350.0 0.7 2.4 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EEB06570.2 - 2.2e-57 193.2 0.0 2.2e-57 193.2 0.0 2.5 2 1 1 3 3 3 1 Microtubule binding DUF4250 PF14056.6 EEB06570.2 - 0.022 14.7 1.3 0.081 12.9 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) HSP70 PF00012.20 EEB06571.1 - 6.2e-267 886.7 10.1 7.1e-267 886.5 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB06571.1 - 4.9e-14 51.9 2.5 3.2e-12 45.9 0.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EEB06571.1 - 0.0043 16.8 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EEB06571.1 - 0.017 14.6 1.5 2.8 7.3 0.0 3.3 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 EEB06571.1 - 0.018 15.4 7.3 1.5 9.3 0.1 3.9 3 2 0 3 3 3 0 Cell division protein FtsA Raco_middle PF17651.1 EEB06571.1 - 0.023 14.4 0.6 9.2 5.9 0.0 2.9 2 0 0 2 2 2 0 RACo middle region SMBP PF16785.5 EEB06571.1 - 0.038 14.2 1.3 0.065 13.5 0.4 1.9 2 0 0 2 2 2 0 Small metal-binding protein 5-FTHF_cyc-lig PF01812.20 EEB06572.2 - 7e-37 127.1 0.0 9e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family F-box-like PF12937.7 EEB06573.1 - 6.8e-10 38.7 0.4 1.4e-09 37.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEB06573.1 - 3.5e-08 33.1 0.4 6.7e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EEB06573.1 - 0.0043 17.9 0.1 0.061 14.2 0.1 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat UIM PF02809.20 EEB06573.1 - 0.011 15.6 12.1 0.39 10.8 3.6 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif F-box_4 PF15966.5 EEB06573.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box RIO1 PF01163.22 EEB06574.1 - 2.4e-47 161.0 0.2 4.5e-47 160.1 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EEB06574.1 - 6.3e-33 112.8 0.1 1.4e-32 111.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EEB06574.1 - 9.9e-12 45.3 0.1 4.8e-05 23.4 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEB06574.1 - 6.7e-07 28.9 0.0 8.3e-05 22.0 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_10 PF13673.7 EEB06575.1 - 8.5e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB06575.1 - 5.2e-08 33.1 0.0 5.9e-08 33.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB06575.1 - 1.2e-06 28.8 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB06575.1 - 1.1e-05 25.5 0.3 4.9e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB06575.1 - 9.9e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 EEB06575.1 - 0.056 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Mlh1_C PF16413.5 EEB06576.1 - 1.4e-73 247.6 2.9 2.6e-73 246.7 2.9 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EEB06576.1 - 1.7e-29 101.9 0.0 3e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EEB06576.1 - 5.1e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EEB06576.1 - 3.4e-05 24.3 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Diphtheria_C PF02763.14 EEB06576.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain Arm PF00514.23 EEB06577.1 - 0.00071 19.5 0.0 0.00071 19.5 0.0 6.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EEB06577.1 - 0.078 12.7 1.8 0.4 10.4 0.0 2.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EEB06577.1 - 2 9.0 10.4 9.3 6.9 0.1 5.9 6 2 1 7 7 7 0 HEAT-like repeat ARID PF01388.21 EEB06578.1 - 5.3e-15 55.9 0.0 1.2e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EEB06578.1 - 0.0091 16.6 0.1 0.043 14.4 0.0 2.3 2 0 0 2 2 2 1 RFX DNA-binding domain DUF4556 PF15094.6 EEB06578.1 - 0.024 13.8 0.1 0.057 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) DUF4042 PF13251.6 EEB06578.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Arm PF00514.23 EEB06578.1 - 5.1 7.3 7.7 0.23 11.6 0.6 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat UPF0086 PF01868.16 EEB06579.1 - 9.9e-25 86.3 0.1 1.7e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SLD5_C PF16922.5 EEB06580.1 - 3.6e-11 43.1 0.1 8.9e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EEB06580.1 - 9.5e-06 26.0 0.2 1.9e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 GINS complex protein DcpS PF05652.12 EEB06581.1 - 1.8e-29 102.6 1.1 3.6e-29 101.7 1.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EEB06581.1 - 3.7e-27 95.1 1.6 5.8e-27 94.4 1.6 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Calreticulin PF00262.18 EEB06582.1 - 5.9e-25 87.9 0.0 2.8e-22 79.1 0.0 2.1 1 1 1 2 2 2 2 Calreticulin family Abhydrolase_6 PF12697.7 EEB06584.1 - 4.9e-21 76.3 0.0 5.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEB06584.1 - 5.8e-14 52.4 0.0 1.8e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEB06584.1 - 1.2e-12 47.6 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EEB06584.1 - 0.0042 16.8 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EEB06584.1 - 0.0095 16.1 0.1 0.024 14.8 0.1 1.8 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EEB06584.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 EEB06584.1 - 0.093 12.5 0.0 0.79 9.5 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 EEB06584.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EEB06584.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SpoOE-like PF09388.10 EEB06585.1 - 0.22 11.4 0.5 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Aconitase PF00330.20 EEB06586.2 - 3.4e-151 504.4 0.0 4.8e-151 503.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEB06586.2 - 4.6e-40 137.0 0.0 8.3e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L21p PF00829.21 EEB06586.2 - 1.7e-16 60.3 0.2 4.3e-16 59.0 0.2 1.8 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF521 PF04412.13 EEB06586.2 - 0.0039 15.9 0.0 0.0075 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Tsi6 PF18660.1 EEB06586.2 - 0.027 14.5 0.1 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Tsi6 SPX PF03105.19 EEB06587.2 - 0.086 12.7 2.4 0.12 12.3 2.3 1.3 1 1 0 1 1 1 0 SPX domain Ribosom_S12_S23 PF00164.25 EEB06588.1 - 1.3e-49 166.6 0.8 1.6e-49 166.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Uso1_p115_head PF04869.14 EEB06589.2 - 6.2e-66 222.7 7.9 6.2e-66 222.7 7.9 2.8 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EEB06589.2 - 8.2e-08 32.7 38.1 8.2e-08 32.7 38.1 5.4 1 1 3 4 4 4 2 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.20 EEB06589.2 - 0.0049 16.3 29.7 0.0049 16.3 29.7 4.3 1 1 1 3 3 3 2 Tropomyosin HEAT_EZ PF13513.6 EEB06589.2 - 0.2 12.2 0.4 52 4.5 0.1 3.6 3 0 0 3 3 3 0 HEAT-like repeat HMMR_N PF15905.5 EEB06589.2 - 4.9 6.5 98.6 1.7 8.0 13.3 4.1 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal PRP3 PF08572.10 EEB06590.1 - 1.4e-67 227.7 15.2 1.4e-67 227.7 15.2 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EEB06590.1 - 4.9e-39 133.8 0.0 4.9e-39 133.8 0.0 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) MUG113 PF13455.6 EEB06590.1 - 0.064 13.9 2.1 3.1 8.5 1.2 2.8 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Lactamase_B_2 PF12706.7 EEB06591.2 - 1e-29 103.5 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EEB06591.2 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB06591.2 - 0.00019 21.5 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 EEB06592.2 - 4.6e-41 140.9 50.9 4.6e-41 140.9 50.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB06592.2 - 1.9e-13 49.8 28.9 2.9e-13 49.1 28.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB06592.2 - 4.9e-13 48.8 11.3 4.9e-13 48.8 11.3 3.7 3 1 0 3 3 3 1 Sugar (and other) transporter CSTF_C PF14304.6 EEB06592.2 - 0.16 11.6 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal CLTH PF10607.9 EEB06593.1 - 2.7e-16 59.8 0.1 2.7e-16 59.8 0.1 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EEB06593.1 - 0.00024 21.1 2.3 0.00024 21.1 2.3 2.6 4 0 0 4 4 4 1 RING-type zinc-finger OmpH PF03938.14 EEB06593.1 - 0.0024 18.2 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) LMP PF04778.12 EEB06593.1 - 0.0083 16.0 0.7 0.2 11.6 0.4 2.2 2 0 0 2 2 2 1 LMP repeated region FCH PF00611.23 EEB06593.1 - 0.018 15.3 1.1 0.052 13.8 0.9 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain LEDGF PF11467.8 EEB06593.1 - 0.032 13.9 0.8 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Rtf2 PF04641.12 EEB06593.1 - 0.06 12.7 0.0 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger FapA PF03961.13 EEB06593.1 - 0.11 11.1 0.5 0.15 10.6 0.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_2 PF13639.6 EEB06593.1 - 4.9 7.6 10.0 0.4 11.0 3.6 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 EEB06593.1 - 9.2 6.2 11.5 0.69 9.8 5.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) THUMP PF02926.17 EEB06594.2 - 6.6e-20 71.7 0.5 3.4e-19 69.4 0.1 2.2 1 1 0 2 2 2 1 THUMP domain Ribosomal_S13 PF00416.22 EEB06594.2 - 0.34 11.3 0.2 0.34 11.3 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF1690 PF07956.11 EEB06595.1 - 4.2e-21 75.8 9.1 4.9e-21 75.6 9.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CortBP2 PF09727.9 EEB06595.1 - 0.00078 19.4 10.2 0.00096 19.1 10.2 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 TLE_N PF03920.15 EEB06595.1 - 0.0078 16.3 3.7 0.011 15.8 3.7 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain DUF4404 PF14357.6 EEB06595.1 - 0.016 15.8 2.3 0.016 15.8 2.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) SF-assemblin PF06705.11 EEB06595.1 - 0.025 13.9 11.0 0.043 13.2 10.9 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin OmpH PF03938.14 EEB06595.1 - 0.034 14.5 6.8 0.049 14.0 6.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4830 PF16112.5 EEB06595.1 - 0.16 12.5 0.4 0.42 11.1 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4830) CENP-H PF05837.12 EEB06595.1 - 2.2 8.7 9.7 0.9 10.0 6.8 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) CorA PF01544.18 EEB06596.1 - 4.4e-08 32.8 3.0 9.1e-08 31.8 3.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4763 PF15960.5 EEB06596.1 - 0.018 14.3 2.6 0.023 14.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF202 PF02656.15 EEB06596.1 - 0.11 12.9 0.3 0.21 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Tim17 PF02466.19 EEB06597.1 - 9.1e-35 119.4 8.1 1.2e-34 119.1 8.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tachystatin_B PF11478.8 EEB06597.1 - 0.21 11.5 1.6 0.36 10.8 0.2 2.0 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B NAC PF01849.18 EEB06598.1 - 3.1e-14 52.7 0.3 3.1e-14 52.7 0.3 2.0 3 0 0 3 3 3 1 NAC domain Ketoacyl-synt_C PF02801.22 EEB06598.1 - 0.017 15.1 0.9 0.035 14.1 0.5 1.7 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF2203 PF09969.9 EEB06598.1 - 0.059 14.1 1.0 0.1 13.3 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CPSF100_C PF13299.6 EEB06598.1 - 5.2 7.2 7.7 19 5.4 7.7 1.8 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal YIF1 PF03878.15 EEB06599.1 - 3.6e-89 298.4 5.2 4.5e-89 298.1 5.2 1.0 1 0 0 1 1 1 1 YIF1 eIF-1a PF01176.19 EEB06600.1 - 1e-21 76.5 0.1 1.4e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Helicase_C_2 PF13307.6 EEB06601.2 - 6.4e-52 176.2 0.0 1.2e-51 175.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EEB06601.2 - 7.6e-49 165.7 0.4 1.5e-48 164.7 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 Vps51 PF08700.11 EEB06602.1 - 3.9e-15 55.7 0.0 5.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 ABC_trans_N PF14510.6 EEB06602.1 - 1.5 9.5 6.2 3.6 8.3 6.2 1.9 1 1 0 1 1 1 0 ABC-transporter N-terminal Glyco_transf_20 PF00982.21 EEB06603.1 - 1e-140 469.6 0.1 1.6e-140 469.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEB06603.1 - 1.6e-59 200.9 0.0 2.6e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EEB06603.1 - 7.5e-08 32.4 0.0 0.0023 17.7 0.1 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 EEB06603.1 - 0.0072 15.9 0.0 0.034 13.7 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Evr1_Alr PF04777.13 EEB06604.1 - 5.4e-26 91.0 1.6 5.4e-26 91.0 1.6 1.9 2 0 0 2 2 2 1 Erv1 / Alr family XPG_N PF00752.17 EEB06605.1 - 1e-36 125.4 0.0 2.1e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EEB06605.1 - 4.4e-30 103.9 0.1 1.1e-29 102.6 0.1 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EEB06605.1 - 0.00045 20.8 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CheD PF03975.13 EEB06605.1 - 0.1 12.7 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 CheD chemotactic sensory transduction Mpv17_PMP22 PF04117.12 EEB06606.2 - 2.7e-22 78.7 2.6 2.7e-22 78.7 2.6 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family RRM_1 PF00076.22 EEB06607.1 - 7.1e-27 93.0 0.8 4.4e-17 61.7 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EEB06607.1 - 0.0057 16.5 0.0 0.91 9.3 0.0 2.8 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EEB06607.1 - 0.016 15.3 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Maf PF02545.14 EEB06608.1 - 7.9e-50 168.9 0.0 9.1e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DSS1_SEM1 PF05160.13 EEB06609.1 - 1.6e-18 66.5 15.5 1.8e-18 66.3 15.5 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4624 PF15417.6 EEB06609.1 - 0.028 14.2 3.0 0.035 13.9 3.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4624) SNF2_N PF00176.23 EEB06610.1 - 3.1e-64 216.9 0.4 5.5e-64 216.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EEB06610.1 - 2.3e-25 88.8 2.5 3.7e-25 88.2 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EEB06610.1 - 7.8e-25 86.5 7.8 3.4e-14 52.5 2.3 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EEB06610.1 - 3e-18 66.2 0.0 1e-17 64.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB06610.1 - 1.4e-09 38.2 0.0 4.7e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EEB06610.1 - 1.9e-09 37.8 0.7 1.9e-09 37.8 0.7 4.9 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 EEB06610.1 - 3.2e-05 24.5 7.8 3.3e-05 24.5 0.3 3.8 3 0 0 3 3 3 1 CDH1/2 SANT-Helical linker 1 CHDCT2 PF08074.11 EEB06610.1 - 6.6e-05 23.1 0.1 0.00054 20.2 0.1 2.7 1 1 0 1 1 1 1 CHDCT2 (NUC038) domain DEAD PF00270.29 EEB06610.1 - 0.00087 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EEB06610.1 - 0.021 15.0 0.0 0.09 13.0 0.0 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain SLIDE PF09111.10 EEB06610.1 - 0.024 14.6 0.0 0.024 14.6 0.0 3.4 3 1 0 3 3 2 0 SLIDE FF PF01846.19 EEB06611.1 - 5.8e-39 132.0 16.7 2.1e-13 50.2 0.1 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 EEB06611.1 - 6.3e-18 64.6 16.5 2.7e-10 40.1 3.4 3.2 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 EEB06611.1 - 1.1e-08 35.6 19.2 6.9e-05 23.4 0.9 6.0 4 1 2 6 6 6 3 p190-A and -B Rho GAPs FF domain DUF348 PF03990.14 EEB06611.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Glyco_hyd_101C PF17451.2 EEB06611.1 - 0.27 11.5 7.5 0.39 11.0 0.8 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain ATP_bind_1 PF03029.17 EEB06612.1 - 9e-87 290.8 0.0 1e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EEB06612.1 - 0.00076 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 EEB06612.1 - 0.0074 16.3 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 EEB06612.1 - 0.028 14.0 0.0 6.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EEB06612.1 - 0.053 12.5 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EEB06612.1 - 0.085 13.0 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEB06612.1 - 0.098 13.2 0.0 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 EEB06612.1 - 0.14 11.0 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase Tau95 PF09734.9 EEB06613.1 - 0.23 12.3 2.7 0.27 12.1 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF4674 PF15719.5 EEB06613.1 - 0.83 9.7 8.0 1 9.3 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) DUF1746 PF08508.10 EEB06614.1 - 9.8e-29 100.0 7.9 1.4e-28 99.5 7.9 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) EamA PF00892.20 EEB06614.1 - 0.063 13.4 7.3 0.55 10.4 4.4 2.4 2 0 0 2 2 2 0 EamA-like transporter family Fijivirus_P9-2 PF06837.11 EEB06614.1 - 0.2 11.1 4.9 0.3 10.5 4.9 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein Spt20 PF12090.8 EEB06615.1 - 3.5e-39 134.8 0.0 3.5e-39 134.8 0.0 3.4 2 1 0 2 2 2 1 Spt20 family NTP_transferase PF00483.23 EEB06616.2 - 2.8e-12 46.8 0.0 6.8e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EEB06616.2 - 1.4e-07 31.0 12.5 4.5e-05 23.0 3.7 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EEB06616.2 - 2.9e-06 25.8 5.3 8.4e-05 20.9 1.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EEB06616.2 - 9.5e-05 22.8 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EEB06616.2 - 0.011 15.5 19.2 0.82 9.5 0.2 4.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 EEB06616.2 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 EEB06616.2 - 0.023 13.6 4.5 0.18 10.7 4.4 2.1 1 1 0 1 1 1 0 L-fucokinase OPT PF03169.15 EEB06617.1 - 8.2e-183 609.4 47.1 9.4e-183 609.2 47.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GATase_6 PF13522.6 EEB06618.1 - 1.2e-14 54.7 0.0 2.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEB06618.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EEB06618.1 - 3.4e-07 29.9 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EEB06618.1 - 1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Dynein_light PF01221.18 EEB06619.2 - 8.7e-40 134.9 0.2 1.1e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 EEB06619.2 - 0.05 13.5 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Ectatomin LRR_4 PF12799.7 EEB06620.1 - 1.5e-13 50.7 20.5 3e-08 33.8 2.5 5.8 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEB06620.1 - 7.8e-13 48.0 18.9 6e-10 38.7 6.2 4.3 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 EEB06620.1 - 1.2e-08 34.3 12.5 0.073 13.2 0.1 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_9 PF14580.6 EEB06620.1 - 2.4e-08 33.7 0.2 1.7e-07 30.9 0.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeat Response_reg PF00072.24 EEB06620.1 - 0.06 13.5 0.1 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain LRR_1 PF00560.33 EEB06620.1 - 0.062 13.9 19.3 10 7.1 0.2 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat HSP90 PF00183.18 EEB06621.1 - 1.6e-223 743.3 28.8 2.1e-223 742.9 28.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EEB06621.1 - 6e-15 55.7 0.1 1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEB06621.1 - 1.9e-10 40.7 0.1 1.9e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 EEB06621.1 - 0.017 15.1 0.4 0.063 13.3 0.0 2.1 2 1 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN EF-hand_6 PF13405.6 EEB06622.1 - 9.4e-10 37.6 0.8 1e-07 31.3 0.3 2.7 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EEB06622.1 - 3.4e-09 35.6 0.9 3.1e-08 32.6 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EEB06622.1 - 6.3e-09 36.2 0.4 7.3e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EEB06622.1 - 2.9e-05 23.4 0.7 7.3e-05 22.1 0.7 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EEB06622.1 - 0.00095 19.0 2.8 0.033 14.0 0.2 2.4 2 2 2 4 4 4 2 EF-hand domain pair DUF853 PF05872.12 EEB06622.1 - 0.1 11.1 0.2 0.15 10.6 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PY_rept_46 PF09689.10 EEB06622.1 - 0.11 13.1 2.2 0.22 12.1 2.2 1.4 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) EF-hand_13 PF17958.1 EEB06622.1 - 0.17 11.7 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain TrbL PF04610.14 EEB06622.1 - 0.22 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein TPR_17 PF13431.6 EEB06623.1 - 7.1e-09 35.4 4.9 0.0037 17.5 0.1 4.8 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06623.1 - 9.4e-07 29.3 8.6 0.16 12.5 0.2 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06623.1 - 3.6e-06 27.2 8.5 0.003 17.8 0.1 4.7 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06623.1 - 4.4e-06 26.3 10.4 1.5 8.8 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06623.1 - 5.2e-06 26.8 1.5 2.3 9.3 0.1 5.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEB06623.1 - 6.5e-06 25.7 9.4 0.0028 17.3 1.8 4.4 6 0 0 6 6 6 1 TPR repeat TPR_2 PF07719.17 EEB06623.1 - 7.1e-05 22.6 12.4 1.9 8.8 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06623.1 - 9.5e-05 23.0 0.7 0.013 16.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06623.1 - 0.00047 20.6 4.4 17 6.3 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEB06623.1 - 0.0013 18.6 0.8 0.12 12.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06623.1 - 0.0043 17.2 9.7 6.9 7.2 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06623.1 - 0.16 12.0 11.2 0.66 10.1 0.0 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB06623.1 - 0.73 10.1 4.5 89 3.4 0.1 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EEB06623.1 - 0.91 9.6 5.3 5.9 7.0 0.1 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain LMWPc PF01451.21 EEB06624.1 - 1.3e-45 155.3 0.0 1.5e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Flavin_Reduct PF01613.18 EEB06625.1 - 5.6e-27 94.7 1.9 1.5e-26 93.3 1.9 1.6 1 1 0 1 1 1 1 Flavin reductase like domain TraI PF07057.11 EEB06625.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 DNA helicase TraI E1-E2_ATPase PF00122.20 EEB06626.1 - 1.3e-43 148.6 7.9 3.9e-43 147.1 4.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EEB06626.1 - 1.6e-18 67.8 0.0 4e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEB06626.1 - 4.4e-08 32.7 0.0 9.2e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEB06626.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEB06626.1 - 0.0032 17.3 0.1 0.0056 16.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2613 PF11021.8 EEB06626.1 - 2.4 8.3 7.4 4.9 7.3 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DnaJ PF00226.31 EEB06627.1 - 6.5e-21 74.2 4.5 1.8e-20 72.8 4.5 1.8 1 0 0 1 1 1 1 DnaJ domain SnoaL_4 PF13577.6 EEB06627.1 - 0.092 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain pXO2-72 PF17443.2 EEB06627.1 - 0.4 11.0 6.4 3.7 7.9 0.3 3.1 3 1 0 3 3 3 0 Uncharacterized protein pXO2-72 FAD_binding_2 PF00890.24 EEB06628.1 - 1.8e-126 422.6 3.6 2.2e-126 422.3 3.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EEB06628.1 - 4.4e-44 149.6 0.3 6.3e-44 149.0 0.3 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EEB06628.1 - 2.8e-06 26.7 1.5 0.0094 15.1 2.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EEB06628.1 - 2.1e-05 23.9 0.2 0.0016 17.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEB06628.1 - 0.00024 20.4 0.3 0.067 12.4 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EEB06628.1 - 0.0037 16.6 0.2 0.0069 15.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EEB06628.1 - 0.027 13.5 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EEB06628.1 - 0.15 11.6 1.6 0.36 10.4 1.6 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EEB06628.1 - 0.35 9.5 3.4 0.75 8.4 1.3 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 EEB06628.1 - 1.5 8.0 2.9 2.8 7.1 1.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SpoIIE PF07228.12 EEB06629.1 - 7.8e-14 52.0 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EEB06629.1 - 2.2e-11 43.9 0.2 3.2e-06 27.0 0.1 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EEB06629.1 - 0.00049 19.8 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C dCMP_cyt_deam_1 PF00383.23 EEB06630.1 - 3.9e-16 58.8 0.8 4.6e-16 58.5 0.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EEB06630.1 - 4.5e-11 43.1 2.0 9.1e-09 35.6 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EEB06630.1 - 9.5e-05 22.1 0.5 0.037 13.6 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Cgr1 PF03879.14 EEB06631.2 - 4.4e-26 91.4 30.7 4.8e-26 91.2 30.7 1.0 1 0 0 1 1 1 1 Cgr1 family DUF4670 PF15709.5 EEB06631.2 - 0.32 10.2 28.9 0.38 10.0 28.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) DNA_repr_REX1B PF14966.6 EEB06632.2 - 1.6e-11 44.7 9.8 2.2e-11 44.2 4.8 2.1 1 1 1 2 2 2 1 DNA repair REX1-B FapA PF03961.13 EEB06632.2 - 0.0046 15.6 9.9 0.0054 15.4 9.9 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF5082 PF16888.5 EEB06632.2 - 0.028 14.7 10.0 0.27 11.5 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BAR_3 PF16746.5 EEB06632.2 - 0.056 13.1 10.1 0.075 12.7 10.1 1.2 1 0 0 1 1 1 0 BAR domain of APPL family CHASE3 PF05227.13 EEB06632.2 - 0.14 12.0 11.2 0.15 12.0 9.7 1.7 1 1 1 2 2 2 0 CHASE3 domain Laminin_II PF06009.12 EEB06632.2 - 0.2 11.6 9.6 0.26 11.3 5.7 2.1 1 1 1 2 2 2 0 Laminin Domain II DASH_Dam1 PF08653.10 EEB06632.2 - 0.25 11.2 3.9 1.4 8.8 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 CdvA PF18822.1 EEB06632.2 - 0.29 11.0 13.4 0.2 11.5 8.7 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Med21 PF11221.8 EEB06632.2 - 0.35 11.1 14.3 0.18 12.0 10.3 2.3 1 1 0 2 2 2 0 Subunit 21 of Mediator complex WXG100 PF06013.12 EEB06632.2 - 0.38 11.0 9.9 9 6.6 0.4 3.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 EEB06632.2 - 0.54 10.3 9.7 2.1 8.4 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med10 PF09748.9 EEB06632.2 - 0.54 10.2 6.3 0.91 9.5 1.5 2.2 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF4140 PF13600.6 EEB06632.2 - 0.63 10.5 10.9 3.2 8.3 4.0 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PspA_IM30 PF04012.12 EEB06632.2 - 0.65 9.5 14.5 0.39 10.3 0.7 2.7 2 1 1 3 3 3 0 PspA/IM30 family Baculo_PEP_C PF04513.12 EEB06632.2 - 0.87 9.6 10.0 9.6 6.2 6.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZnuA PF01297.17 EEB06632.2 - 0.96 8.8 5.1 7.9 5.8 0.8 2.1 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Jnk-SapK_ap_N PF09744.9 EEB06632.2 - 1.1 9.4 15.9 1.7 8.8 15.9 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 NEMO PF11577.8 EEB06632.2 - 1.2 9.2 10.1 5.1 7.2 7.4 2.9 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO FlaC_arch PF05377.11 EEB06632.2 - 2 8.9 10.2 1.9 9.0 1.9 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EEB06632.2 - 3.1 7.9 17.6 9.4 6.3 11.5 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding KfrA_N PF11740.8 EEB06632.2 - 3.9 8.2 9.3 12 6.6 3.2 2.4 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF2203 PF09969.9 EEB06632.2 - 6.3 7.5 9.2 16 6.2 5.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_L31e PF01198.19 EEB06633.1 - 1.1e-40 137.8 1.8 1.6e-40 137.2 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EEB06633.1 - 0.033 14.2 0.1 0.039 14.0 0.1 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein SbcCD_C PF13558.6 EEB06634.2 - 0.00013 22.2 0.0 0.00043 20.5 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit PI3K_P85_iSH2 PF16454.5 EEB06634.2 - 0.007 16.0 20.4 0.007 16.0 20.4 7.4 2 1 5 7 7 7 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Laminin_II PF06009.12 EEB06634.2 - 0.008 16.2 3.6 0.008 16.2 3.6 9.8 4 2 5 10 10 10 1 Laminin Domain II PilJ PF13675.6 EEB06634.2 - 0.25 11.4 38.0 2.8 8.0 0.5 7.7 4 3 4 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3618 PF12277.8 EEB06634.2 - 0.8 10.0 3.3 2.7 8.3 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SCO1-SenC PF02630.14 EEB06634.2 - 2.5 8.0 6.0 27 4.7 0.0 4.2 4 1 0 4 4 4 0 SCO1/SenC SPRY PF00622.28 EEB06635.2 - 4e-25 88.3 1.5 7.4e-25 87.4 0.9 1.8 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 EEB06635.2 - 1.3e-15 57.6 0.0 1.9e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EEB06635.2 - 0.001 18.9 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 LisH UQ_con PF00179.26 EEB06636.2 - 3e-48 163.0 0.0 4e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEB06636.2 - 0.00025 21.3 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EEB06636.2 - 0.00037 20.4 0.1 0.00062 19.6 0.1 1.4 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 EEB06636.2 - 0.002 17.8 0.0 0.0087 15.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 EEB06636.2 - 0.0033 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase PF00069.25 EEB06637.1 - 3.3e-69 233.2 0.0 4.5e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06637.1 - 2.8e-28 98.9 0.0 4.3e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06637.1 - 3e-07 30.0 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB06637.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATA PF00320.27 EEB06638.1 - 1.5e-14 53.3 5.6 3e-14 52.3 5.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Cpn10 PF00166.21 EEB06639.1 - 1.9e-26 91.9 0.0 2.2e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pex24p PF06398.11 EEB06640.1 - 5.4e-27 94.7 4.6 1.1e-26 93.8 4.6 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Arrestin_C PF02752.22 EEB06641.1 - 2.5e-19 70.0 0.0 3.4e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEB06641.1 - 7.4e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.25 EEB06643.1 - 1.7e-50 171.2 3.6 2e-50 171.0 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB06643.1 - 1.5e-33 116.3 1.3 1.8e-33 116.1 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB06643.1 - 1.4e-13 51.2 0.4 1.9e-13 50.7 0.4 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEB06643.1 - 1.6e-05 24.2 2.0 2.2e-05 23.8 2.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EEB06643.1 - 0.043 13.6 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EEB06643.1 - 0.099 12.1 0.6 0.17 11.3 0.6 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_1 PF00667.20 EEB06645.1 - 6.8e-69 231.8 0.0 1.1e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEB06645.1 - 9.3e-08 32.7 0.0 3.9e-06 27.5 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEB06645.1 - 0.0027 18.0 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain GBP_repeat PF02526.14 EEB06645.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 Glycophorin-binding protein Copper-fist PF00649.18 EEB06646.1 - 4.4e-20 70.9 0.9 9.1e-20 69.9 0.9 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Ran-binding PF05508.11 EEB06647.1 - 1.2e-87 293.9 1.3 1.5e-87 293.5 1.3 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 EEB06648.1 - 6e-46 156.4 0.0 9.3e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEB06648.1 - 1.5e-34 118.6 0.3 5.5e-34 116.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEB06648.1 - 0.00011 22.5 0.1 0.00027 21.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB06648.1 - 0.00093 19.3 0.1 0.0071 16.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.10 EEB06648.1 - 0.24 10.8 11.2 0.37 10.1 11.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sec1 PF00995.23 EEB06649.1 - 2e-106 357.5 1.5 2e-106 357.5 1.5 1.4 2 0 0 2 2 2 1 Sec1 family AP3D1 PF06375.11 EEB06649.1 - 0.51 10.6 11.9 0.99 9.6 11.9 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RPA_C PF08784.11 EEB06650.1 - 4.5e-20 72.3 0.1 9.5e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EEB06650.1 - 2e-05 24.4 0.1 3.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EEB06650.1 - 0.0096 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Git3 PF11710.8 EEB06651.1 - 8.7e-41 139.9 19.8 8.7e-41 139.9 19.8 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EEB06651.1 - 0.00073 19.6 0.6 0.00073 19.6 0.6 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2207 PF09972.9 EEB06651.1 - 0.56 8.9 5.2 1.3 7.7 5.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Meiotic_rec114 PF03525.14 EEB06652.1 - 0.019 14.0 0.1 0.021 13.8 0.1 1.2 1 1 0 1 1 1 0 Meiotic recombination protein rec114 Inositol_P PF00459.25 EEB06653.1 - 1.1e-50 172.6 0.1 3.4e-50 171.1 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Sigma70_r4 PF04545.16 EEB06653.1 - 0.13 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 zf-C3HC PF07967.13 EEB06654.1 - 1.9e-14 53.8 7.5 2e-13 50.5 1.7 2.7 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EEB06654.1 - 3.4e-09 36.7 0.6 3.4e-09 36.7 0.6 2.8 3 1 0 3 3 3 1 Rsm1-like BIR PF00653.21 EEB06654.1 - 0.0056 17.3 3.5 0.016 15.8 0.2 2.6 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain PMAIP1 PF15150.6 EEB06654.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced TCO89 PF10452.9 EEB06655.2 - 1.3e-09 37.6 0.1 1.3e-09 37.6 0.1 2.1 2 0 0 2 2 2 2 TORC1 subunit TCO89 Ribosomal_L37 PF08561.10 EEB06656.1 - 7.6e-19 68.4 3.5 2.1e-18 67.0 3.5 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 PolyA_pol PF01743.20 EEB06657.1 - 5.8e-21 75.2 0.0 1.1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EEB06657.1 - 1.7e-07 30.9 0.0 4.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A MU117 PF15474.6 EEB06658.1 - 4.3e-20 72.4 8.5 5.5e-20 72.0 8.5 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family AbiH PF14253.6 EEB06659.1 - 0.0013 18.7 5.0 0.0015 18.5 5.0 1.2 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH NFACT-C PF11923.8 EEB06659.1 - 0.43 10.5 6.0 0.19 11.7 0.7 2.5 2 0 0 2 2 2 0 NFACT protein C-terminal domain Lipoprotein_10 PF03202.13 EEB06659.1 - 2 8.9 8.5 1.5 9.3 0.7 2.5 1 1 1 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region TFIIS_M PF07500.14 EEB06660.2 - 4.3e-25 88.4 0.6 8.4e-25 87.4 0.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EEB06660.2 - 2.5e-21 76.2 0.0 6.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EEB06660.2 - 1.2e-11 44.3 6.8 2.1e-11 43.5 6.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEB06660.2 - 0.0025 17.3 2.6 0.0045 16.5 2.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EEB06660.2 - 0.011 15.7 1.0 0.024 14.7 1.0 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger ER-remodelling PF14755.6 EEB06660.2 - 0.016 15.5 0.9 0.016 15.5 0.9 3.0 4 1 1 5 5 5 0 Intracellular membrane remodeller HipN PF18253.1 EEB06660.2 - 0.15 11.7 0.5 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Mei5 PF10376.9 EEB06661.1 - 1e-20 74.5 0.7 4e-20 72.6 0.7 1.9 1 1 0 1 1 1 1 Double-strand recombination repair protein Uso1_p115_C PF04871.13 EEB06661.1 - 0.037 14.4 0.3 0.095 13.1 0.3 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sel1 PF08238.12 EEB06662.1 - 1.2e-20 73.5 16.9 0.0017 19.0 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat Chi-conotoxin PF16981.5 EEB06662.1 - 0.0071 16.6 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 chi-Conotoxin or t superfamily TMEM154 PF15102.6 EEB06662.1 - 0.013 15.4 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family TPR_6 PF13174.6 EEB06662.1 - 8.1 7.3 13.5 13 6.7 0.0 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat TFIIA PF03153.13 EEB06663.2 - 2.7e-81 274.7 5.7 3.1e-81 274.5 5.7 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4712 PF15830.5 EEB06663.2 - 1.3 8.6 5.5 2.9 7.5 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Ada3 PF10198.9 EEB06664.1 - 6.4e-30 104.0 6.8 1.7e-29 102.6 6.8 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 HMG_box_2 PF09011.10 EEB06665.1 - 2.4e-18 66.5 1.6 2.4e-18 66.5 1.6 2.7 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 EEB06665.1 - 7.8e-16 58.3 1.7 7.8e-16 58.3 1.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box RNA_pol_Rpb1_1 PF04997.12 EEB06666.1 - 2.9e-121 404.6 0.0 4.4e-121 404.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EEB06666.1 - 7.2e-110 366.6 0.1 1e-109 366.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEB06666.1 - 1.2e-77 259.9 0.0 2.6e-77 258.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EEB06666.1 - 2.9e-61 206.6 0.5 5.8e-61 205.7 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EEB06666.1 - 2.6e-51 173.1 2.2 5.8e-51 172.0 2.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 EEB06666.1 - 1.8e-49 167.7 0.0 4.5e-49 166.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEB06666.1 - 7.9e-40 135.2 0.1 1.8e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EEB06666.1 - 1.1e-11 44.4 324.3 0.18 12.2 13.9 15.7 10 1 0 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat Pro_isomerase PF00160.21 EEB06667.2 - 2.7e-48 164.2 0.2 2.9e-48 164.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DFRP_C PF16543.5 EEB06668.1 - 2e-23 82.7 5.4 2e-23 82.7 5.4 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Cyclin PF08613.11 EEB06669.2 - 9e-08 32.6 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EEB06669.2 - 0.0032 17.2 1.0 0.014 15.1 1.0 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Phage_CP76 PF06892.11 EEB06669.2 - 0.024 14.2 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) RRM_1 PF00076.22 EEB06670.1 - 1.6e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EEB06670.1 - 3.3e-06 27.6 2.3 3.3e-06 27.6 2.3 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.25 EEB06671.1 - 2.9e-69 233.4 0.0 3.9e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06671.1 - 3.1e-49 167.6 0.0 5.2e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 EEB06671.1 - 7.5e-12 45.5 1.6 1.1e-11 45.0 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EEB06671.1 - 2e-11 43.8 1.2 3.6e-11 43.0 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 EEB06671.1 - 1.5e-08 34.9 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 EEB06671.1 - 1.7e-06 27.5 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB06671.1 - 0.0055 15.5 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EEB06671.1 - 0.018 14.0 1.8 0.12 11.3 0.0 2.4 3 0 0 3 3 3 0 Haspin like kinase domain Ribosomal_L5_C PF00673.21 EEB06672.1 - 2.3e-19 69.4 0.0 3.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEB06672.1 - 1.1e-11 44.9 0.2 1.9e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 EST1_DNA_bind PF10373.9 EEB06673.1 - 1.1e-33 117.0 3.1 1.8e-33 116.2 3.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EEB06673.1 - 1.6e-19 70.9 0.2 5.7e-19 69.1 0.2 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 Ribosomal_L22 PF00237.19 EEB06674.1 - 1.1e-38 131.6 0.1 1.6e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Oxysterol_BP PF01237.18 EEB06675.1 - 2.4e-130 434.7 0.8 5.3e-130 433.6 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EEB06675.1 - 4.2e-19 68.3 0.2 2.8e-08 33.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB06675.1 - 1.5e-16 60.8 0.1 6e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 EEB06675.1 - 1.7e-16 60.6 1.8 6.8e-15 55.5 0.1 2.8 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 EEB06675.1 - 3.3e-13 49.9 0.1 5.7e-05 23.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEB06675.1 - 3.7e-13 48.3 0.2 5.3e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EEB06675.1 - 1.2e-10 41.3 0.2 3.4e-05 24.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat PH_8 PF15409.6 EEB06675.1 - 4.5e-08 33.3 0.7 1.2e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EEB06675.1 - 8.8e-05 22.9 2.0 8.8e-05 22.9 2.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3990 PF13151.6 EEB06675.1 - 0.0029 17.3 0.7 0.0083 15.8 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) mRNA_cap_enzyme PF01331.19 EEB06677.1 - 3.1e-58 196.8 0.1 4.4e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EEB06677.1 - 2.6e-36 124.5 0.0 4.4e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EEB06677.1 - 1.6e-07 31.2 0.0 0.00096 18.8 0.0 2.7 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EEB06677.1 - 0.00022 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase bZIP_1 PF00170.21 EEB06678.1 - 1.9e-08 34.3 12.3 3.8e-08 33.3 12.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEB06678.1 - 1.6e-05 24.8 11.0 4e-05 23.6 11.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EEB06678.1 - 0.0029 18.1 10.7 0.0062 17.0 10.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor PBP PF01161.20 EEB06679.1 - 1.1e-05 25.8 0.1 2.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Apolipoprotein PF01442.18 EEB06681.1 - 0.0011 18.9 11.4 0.0034 17.3 11.4 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Grg1 PF11034.8 EEB06681.1 - 0.0014 18.8 9.0 0.0014 18.8 9.0 3.1 2 1 0 2 2 2 1 Glucose-repressible protein Grg1 YtxH PF12732.7 EEB06681.1 - 0.0027 18.2 29.6 0.051 14.1 11.8 3.2 1 1 2 3 3 3 2 YtxH-like protein DUF883 PF05957.13 EEB06681.1 - 0.012 16.1 18.1 1.8 9.2 6.3 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 EEB06681.1 - 0.029 14.5 16.8 0.055 13.6 16.6 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Aida_N PF08910.10 EEB06681.1 - 0.97 9.9 11.1 5.1 7.5 3.0 2.4 1 1 0 2 2 2 0 Aida N-terminus REF PF05755.12 EEB06681.1 - 3 7.6 8.0 1.3 8.8 5.1 1.7 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) ApoO PF09769.9 EEB06681.1 - 4.5 7.3 6.9 1.3e+02 2.5 6.9 2.8 1 1 0 1 1 1 0 Apolipoprotein O Ndc1_Nup PF09531.10 EEB06681.1 - 9.8 4.7 13.5 13 4.4 13.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoLip_ATPase_C PF16212.5 EEB06682.1 - 6.4e-75 252.1 25.6 6.4e-75 252.1 25.6 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEB06682.1 - 5.6e-22 77.2 3.1 5.6e-22 77.2 3.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEB06682.1 - 1.7e-12 47.2 0.0 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEB06682.1 - 1.5e-11 45.0 0.2 1.6e-05 25.3 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEB06682.1 - 9.7e-06 25.2 1.6 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEB06682.1 - 0.0036 17.1 1.3 0.016 15.0 0.3 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Nup_retrotrp_bd PF10599.9 EEB06682.1 - 0.085 13.5 1.0 0.24 12.1 1.0 1.7 1 0 0 1 1 1 0 Retro-transposon transporting motif WH1 PF00568.23 EEB06683.2 - 4e-25 87.9 0.0 6.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain NAC PF01849.18 EEB06684.1 - 2.1e-20 72.4 0.6 2.1e-20 72.4 0.6 1.6 2 0 0 2 2 2 1 NAC domain Sod_Fe_C PF02777.18 EEB06685.1 - 2.5e-22 78.9 1.1 3.7e-22 78.4 1.1 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Beach PF02138.18 EEB06686.2 - 4.6e-119 396.9 0.5 9.9e-119 395.8 0.5 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EEB06686.2 - 5e-09 36.2 0.1 1.9e-08 34.3 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 EEB06686.2 - 2.7e-06 26.8 13.2 0.004 16.4 1.4 3.9 3 1 0 3 3 3 3 Domain of unknown function (DUF4704) WD40 PF00400.32 EEB06686.2 - 9.2e-06 26.3 3.6 0.12 13.3 0.3 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat FYVE PF01363.21 EEB06686.2 - 0.0044 17.1 14.2 0.011 15.8 14.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger Laminin_G_3 PF13385.6 EEB06686.2 - 0.014 15.5 0.1 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily FYVE_2 PF02318.16 EEB06686.2 - 0.21 11.8 10.6 0.66 10.2 10.6 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger BAG PF02179.16 EEB06687.1 - 3.6e-18 65.8 1.2 8.2e-18 64.6 1.2 1.6 1 0 0 1 1 1 1 BAG domain PCC_BT PF18140.1 EEB06687.1 - 0.0035 17.7 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain TUG-UBL1 PF11470.8 EEB06687.1 - 0.039 14.2 0.2 0.71 10.1 0.0 2.5 2 1 0 2 2 2 0 TUG ubiquitin-like domain Shisa PF13908.6 EEB06687.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Dynactin_p62 PF05502.13 EEB06689.2 - 1.8e-09 36.9 32.4 4e-08 32.5 25.9 2.4 1 1 0 2 2 2 2 Dynactin p62 family Endopep_inhib PF16800.5 EEB06689.2 - 0.089 12.7 0.2 0.41 10.6 0.1 2.0 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor Fungal_trans PF04082.18 EEB06690.2 - 1.2e-20 73.6 0.9 3.1e-20 72.3 0.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB06690.2 - 2.6e-11 43.4 10.8 4.3e-11 42.7 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLU PF13236.6 EEB06691.1 - 5.5e-73 245.4 0.0 1.2e-72 244.3 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EEB06691.1 - 1.2e-35 123.1 0.7 3.4e-35 121.7 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EEB06691.1 - 6.5e-19 68.0 1.4 5.3e-07 29.8 0.0 5.1 3 1 2 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 EEB06691.1 - 1.6e-18 66.8 0.4 4e-18 65.6 0.4 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EEB06691.1 - 3.5e-15 55.3 0.0 0.00051 19.8 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF727 PF05303.12 EEB06691.1 - 0.00084 19.4 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 EEB06691.1 - 1.1 9.2 6.6 0.39 10.6 1.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06691.1 - 4.2 7.7 14.6 1.4 9.2 1.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TENA_THI-4 PF03070.16 EEB06692.1 - 4.7e-06 26.6 0.5 4e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 TENA/THI-4/PQQC family ThiJ_like PF17124.5 EEB06693.1 - 9.7e-66 221.2 0.0 1.3e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like RRN3 PF05327.11 EEB06694.1 - 7.1e-167 556.3 8.8 8.3e-167 556.1 8.8 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Dynein_AAA_lid PF17852.1 EEB06694.1 - 0.12 12.4 0.4 3.5 7.7 0.1 3.0 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain MSC PF09402.10 EEB06695.1 - 3.4e-69 233.9 0.2 6.4e-69 233.0 0.2 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EEB06695.1 - 7.2e-12 44.8 0.1 1.4e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.9 EEB06695.1 - 0.00022 21.2 0.0 0.00075 19.4 0.0 2.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding PNRC PF15365.6 EEB06696.1 - 2.8e-06 27.0 1.2 2.8e-06 27.0 1.2 2.8 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif CS PF04969.16 EEB06697.1 - 1e-17 64.9 1.6 2.1e-17 63.9 1.6 1.5 1 0 0 1 1 1 1 CS domain LIM_bind PF01803.16 EEB06697.1 - 0.0068 16.0 0.4 0.009 15.6 0.4 1.2 1 0 0 1 1 1 1 LIM-domain binding protein EF-hand_13 PF17958.1 EEB06697.1 - 0.033 14.0 0.1 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain ox_reductase_C PF08635.10 EEB06697.1 - 0.04 13.6 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain CdiI_4 PF18624.1 EEB06697.1 - 0.065 13.7 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 CDI immunity protein PNPase PF03726.14 EEB06697.1 - 0.072 13.6 0.6 0.14 12.7 0.6 1.5 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ANTH PF07651.16 EEB06698.1 - 6.5e-62 209.0 0.8 8.3e-62 208.7 0.8 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EEB06698.1 - 2.6e-09 37.2 1.2 4.1e-09 36.5 0.3 1.8 2 0 0 2 2 2 1 ENTH domain Snf7 PF03357.21 EEB06698.1 - 0.094 12.3 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Snf7 SNase PF00565.17 EEB06699.1 - 2.9e-20 72.8 0.0 4.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SPC12 PF06645.13 EEB06700.2 - 5.4e-21 74.5 0.3 8.3e-21 73.9 0.3 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L1 PF00687.21 EEB06701.1 - 4.4e-35 121.3 10.1 5.5e-35 120.9 10.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ldh_1_C PF02866.18 EEB06702.1 - 3.3e-47 160.5 0.0 5.8e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EEB06702.1 - 8.9e-40 136.0 0.4 1.3e-39 135.5 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEB06702.1 - 0.0049 15.9 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EEB06702.1 - 0.11 13.0 0.5 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CAP_N PF01213.19 EEB06703.1 - 4.3e-109 364.8 6.1 4.3e-109 364.8 6.1 1.9 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EEB06703.1 - 1.2e-59 200.4 6.6 1.8e-59 199.8 6.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EEB06703.1 - 0.0003 20.5 8.3 0.0005 19.8 6.9 1.9 1 1 1 2 2 2 2 Tubulin binding cofactor C PLDc_2 PF13091.6 EEB06704.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 PLD-like domain GCP_N_terminal PF17681.1 EEB06705.1 - 1.5e-06 28.1 1.5 2.9e-06 27.1 0.3 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal PB1 PF00564.24 EEB06705.1 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 PB1 domain UK PF02512.14 EEB06706.1 - 0.03 14.9 0.1 0.036 14.6 0.1 1.1 1 0 0 1 1 1 0 Virulence determinant SRP68 PF16969.5 EEB06707.1 - 2.4e-43 149.0 8.9 1.1e-42 146.9 8.9 2.0 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 OST3_OST6 PF04756.13 EEB06707.1 - 0.017 14.5 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family SAS4 PF15460.6 EEB06707.1 - 0.07 13.2 0.5 0.7 10.0 0.0 2.6 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF4924 PF16271.5 EEB06707.1 - 0.14 12.1 1.6 6 6.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4924) EF-hand_7 PF13499.6 EEB06708.1 - 2.8e-26 91.8 12.9 6.5e-14 52.1 3.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EEB06708.1 - 7.7e-26 87.7 19.2 1.6e-07 30.4 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EEB06708.1 - 1.9e-21 74.1 12.9 1.6e-07 30.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EEB06708.1 - 7.9e-11 41.6 13.5 9.2e-08 31.8 0.9 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EEB06708.1 - 1.5e-10 41.2 1.0 0.00056 20.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EEB06708.1 - 6.1e-09 35.0 14.6 0.0011 18.4 1.3 4.5 4 1 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EEB06708.1 - 1.1e-05 25.4 3.8 0.018 15.0 0.7 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EEB06708.1 - 0.00089 19.2 0.8 0.63 9.9 0.0 3.4 1 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EEB06708.1 - 0.013 15.8 3.1 2.5 8.4 0.6 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EEB06708.1 - 0.018 15.3 2.7 4 7.9 0.4 2.4 2 1 0 2 2 2 0 EF-hand domain EF-hand_11 PF08976.11 EEB06708.1 - 0.019 15.9 1.3 5.4 7.9 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 EEB06708.1 - 0.042 14.0 0.5 0.089 13.0 0.3 1.7 2 0 0 2 2 2 0 Dockerin type I domain AMNp_N PF10423.9 EEB06708.1 - 0.13 11.9 0.0 0.36 10.5 0.1 1.6 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Ribosomal_L12 PF00542.19 EEB06708.1 - 0.18 12.2 0.9 0.4 11.0 0.0 2.0 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain CDC45 PF02724.14 EEB06709.1 - 0.046 12.0 6.5 0.061 11.6 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein REV PF00424.18 EEB06709.1 - 0.11 12.5 0.3 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) GREB1 PF15782.5 EEB06709.1 - 0.62 7.1 12.5 0.73 6.9 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 EEB06709.1 - 0.94 8.3 17.8 1.4 7.7 17.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EEB06709.1 - 1.8 7.0 16.3 2.4 6.6 16.3 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 EEB06709.1 - 2.2 6.5 8.0 2.9 6.1 8.0 1.1 1 0 0 1 1 1 0 Menin SOBP PF15279.6 EEB06709.1 - 3.2 8.3 18.6 5.4 7.5 18.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SSP160 PF06933.11 EEB06709.1 - 4.7 5.3 26.1 6.8 4.8 26.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MCM PF00493.23 EEB06710.2 - 8.3e-71 237.6 0.5 4.9e-44 150.1 0.1 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EEB06710.2 - 1.6e-34 118.5 0.0 3.1e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEB06710.2 - 3.9e-22 78.5 2.5 9.6e-22 77.2 1.8 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EEB06710.2 - 5.1e-14 52.7 0.1 1.8e-13 51.0 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain RcpC PF16976.5 EEB06710.2 - 0.16 12.0 0.1 0.16 12.0 0.1 2.7 2 1 1 3 3 3 0 Flp pilus assembly protein RcpC/CpaB DUF4778 PF16008.5 EEB06710.2 - 8.1 6.4 8.7 13 5.7 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) UCR_UQCRX_QCR9 PF05365.12 EEB06711.2 - 1.4e-24 85.7 0.6 1.6e-24 85.6 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ANAPC4_WD40 PF12894.7 EEB06712.2 - 0.00011 22.4 0.1 0.46 10.8 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB06712.2 - 0.00099 19.9 1.4 0.016 16.1 0.1 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Beta_propel PF09826.9 EEB06712.2 - 0.1 11.4 0.0 13 4.5 0.0 2.9 3 0 0 3 3 3 0 Beta propeller domain RNA_pol_N PF01194.17 EEB06713.1 - 1.1e-32 112.1 0.5 1.3e-32 111.9 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit SHMT PF00464.19 EEB06714.1 - 6.3e-203 673.7 0.0 7.2e-203 673.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EEB06714.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase CHCH PF06747.13 EEB06715.1 - 1.2e-05 25.3 1.3 1.8e-05 24.7 1.3 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EEB06715.1 - 0.0022 18.0 0.1 0.0027 17.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EEB06715.1 - 0.02 14.9 0.8 0.036 14.1 0.8 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 EEB06715.1 - 0.099 12.9 0.0 3 8.1 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein OTU PF02338.19 EEB06716.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease Septin PF00735.18 EEB06717.2 - 8.4e-84 281.2 0.0 1.5e-83 280.4 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEB06717.2 - 2e-06 27.9 0.0 4.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EEB06717.2 - 0.00071 19.2 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.18 EEB06717.2 - 0.0013 18.2 0.0 0.0045 16.4 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Roc PF08477.13 EEB06717.2 - 0.0054 16.9 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 EEB06717.2 - 0.0058 16.2 0.4 0.01 15.5 0.4 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit GTP_EFTU PF00009.27 EEB06717.2 - 0.015 14.9 1.2 3.4 7.2 0.3 3.2 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EEB06717.2 - 0.02 14.2 0.9 0.033 13.5 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 EEB06717.2 - 0.02 14.8 2.4 0.065 13.1 0.2 2.6 3 0 0 3 3 3 0 RsgA GTPase SRPRB PF09439.10 EEB06717.2 - 0.058 12.8 0.2 0.058 12.8 0.2 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ThrE PF06738.12 EEB06718.2 - 7.4e-57 192.5 23.9 1.5e-55 188.2 7.1 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EEB06718.2 - 4.7e-11 42.9 26.8 4e-09 36.7 12.6 2.5 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE PHO4 PF01384.20 EEB06718.2 - 0.017 14.2 11.6 0.011 14.8 9.8 1.6 2 0 0 2 2 2 0 Phosphate transporter family PC4 PF02229.16 EEB06719.1 - 8.4e-22 76.6 0.4 1.3e-21 76.0 0.4 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CobT PF06213.12 EEB06719.1 - 0.0041 16.5 2.8 0.0041 16.5 2.8 1.4 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF4598 PF15370.6 EEB06719.1 - 0.43 11.1 9.3 0.091 13.2 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) zf-C3H2C3 PF17122.5 EEB06720.2 - 8.3e-20 70.5 7.7 8.3e-20 70.5 7.7 2.1 3 0 0 3 3 3 1 Zinc-finger Clathrin PF00637.20 EEB06720.2 - 0.0021 17.9 4.7 0.0021 17.9 4.7 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS DUF4455 PF14643.6 EEB06720.2 - 0.0059 15.3 0.2 0.0092 14.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) C1_2 PF03107.16 EEB06720.2 - 0.0075 16.6 0.7 0.034 14.5 0.7 2.2 1 0 0 1 1 1 1 C1 domain DZR PF12773.7 EEB06720.2 - 0.057 13.4 5.3 0.067 13.2 2.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon BfiI_DBD PF18243.1 EEB06720.2 - 0.2 11.2 0.8 0.63 9.6 0.1 2.1 3 0 0 3 3 3 0 Metal-independent restriction enzyme BfiI DNA binding domain zf-C3HC4_2 PF13923.6 EEB06720.2 - 0.39 10.6 7.2 1.1 9.1 7.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEB06720.2 - 0.56 9.9 5.7 1.8 8.2 5.7 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ribbon_3 PF13248.6 EEB06720.2 - 1.3 8.5 5.5 15 5.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PADR1 PF08063.12 EEB06720.2 - 2.2 8.1 8.1 11 5.9 1.4 2.7 1 1 1 2 2 2 0 PADR1 (NUC008) domain Ras PF00071.22 EEB06721.2 - 8.3e-49 165.3 0.0 1e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB06721.2 - 8.7e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB06721.2 - 1.1e-06 28.2 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEB06721.2 - 0.031 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EEB06721.2 - 0.046 14.2 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EEB06721.2 - 0.077 12.3 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.10 EEB06722.1 - 2.2e-22 79.0 1.9 2.8e-22 78.7 1.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EEB06722.1 - 0.0013 18.7 0.2 0.0018 18.2 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 HAP1_N PF04849.13 EEB06722.1 - 0.016 14.4 0.1 0.016 14.4 0.1 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region zf-Nse PF11789.8 EEB06723.1 - 3.4e-20 71.6 0.9 6.9e-20 70.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 EEB06723.1 - 0.001 18.8 1.4 0.0019 17.9 1.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger MIEAP PF16026.5 EEB06723.1 - 0.0039 17.4 2.6 0.0062 16.8 2.6 1.4 1 0 0 1 1 1 1 Mitochondria-eating protein zf-C3HC4_2 PF13923.6 EEB06723.1 - 0.0064 16.3 1.4 0.015 15.1 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 EEB06723.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EEB06723.1 - 0.089 12.8 3.9 0.28 11.3 3.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF5082 PF16888.5 EEB06723.1 - 0.28 11.5 7.2 1.2 9.4 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF737 PF05300.11 EEB06723.1 - 0.43 10.9 7.0 1.1 9.6 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF737) FlaC_arch PF05377.11 EEB06723.1 - 0.53 10.7 5.7 0.46 10.9 0.3 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SbcD_C PF12320.8 EEB06723.1 - 0.6 10.4 7.4 0.16 12.3 3.9 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Myb_DNA-binding PF00249.31 EEB06724.2 - 0.0066 16.6 0.1 0.018 15.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain FlxA PF14282.6 EEB06724.2 - 7.5 6.6 8.0 1.9 8.5 3.5 2.4 2 0 0 2 2 2 0 FlxA-like protein Med13_C PF06333.12 EEB06725.1 - 5.4e-16 58.8 0.1 1.4e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EEB06725.1 - 1.7e-08 34.3 1.1 4.6e-08 32.8 1.1 1.7 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal GST_C_6 PF17171.4 EEB06727.1 - 6.5e-12 45.1 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EEB06727.1 - 1.4e-07 31.9 1.0 9.7e-07 29.1 1.0 2.1 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EEB06727.1 - 3.1e-06 27.9 0.0 1.1e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Pox_VP8_L4R PF04498.12 EEB06727.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R GST_C_2 PF13410.6 EEB06727.1 - 0.096 12.7 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Q_salvage PF10343.9 EEB06728.1 - 5.4e-110 367.4 0.0 6.3e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Pho88 PF10032.9 EEB06729.1 - 3.8e-65 218.6 0.1 4.3e-65 218.4 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.32 EEB06730.2 - 4.2e-07 30.6 0.0 1.7 9.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06730.2 - 5.8e-05 23.3 0.0 0.027 14.8 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GDP_Man_Dehyd PF16363.5 EEB06731.1 - 2.4e-53 181.7 0.0 2.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEB06731.1 - 1.1e-51 175.6 0.0 1.5e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEB06731.1 - 4.2e-16 58.8 0.0 2.3e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EEB06731.1 - 9.4e-13 47.9 0.0 2.6e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EEB06731.1 - 1.8e-08 34.5 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EEB06731.1 - 2.1e-07 30.6 0.0 4.7e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EEB06731.1 - 6.2e-07 28.8 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EEB06731.1 - 4e-06 26.2 0.0 0.0009 18.5 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EEB06731.1 - 7.3e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEB06731.1 - 0.00012 21.8 0.0 0.00054 19.6 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EEB06731.1 - 0.005 16.4 0.1 0.0089 15.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 EEB06731.1 - 0.036 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PCMT PF01135.19 EEB06731.1 - 0.046 13.5 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH_N PF02737.18 EEB06731.1 - 0.053 13.4 0.2 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GAT PF03127.14 EEB06732.1 - 0.0059 16.9 0.3 0.0059 16.9 0.3 2.9 3 0 0 3 3 3 1 GAT domain DASH_Dam1 PF08653.10 EEB06732.1 - 0.047 13.5 1.1 14 5.5 0.0 3.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 MtrB PF05440.12 EEB06732.1 - 0.11 12.9 0.6 3.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B FUSC PF04632.12 EEB06732.1 - 0.62 8.5 3.5 0.4 9.1 1.4 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Sirohm_synth_C PF14823.6 EEB06733.1 - 3.2e-19 68.3 0.1 5.3e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EEB06733.1 - 4.8e-15 54.7 0.2 7.9e-15 54.0 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 EEB06733.1 - 1.7e-14 54.1 0.6 4.2e-13 49.6 0.6 2.3 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EEB06733.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EEB06734.1 - 1.4e-62 211.5 0.0 2.7e-62 210.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06734.1 - 2.2e-42 145.1 0.0 3.4e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EEB06734.1 - 1.3e-20 73.0 25.2 2.5e-10 40.1 7.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EEB06734.1 - 4.6e-15 55.5 8.7 3.4e-12 46.3 0.9 2.6 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EEB06734.1 - 2.5e-08 34.5 0.2 8e-08 32.9 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EEB06734.1 - 4.7e-05 23.6 0.2 9.1e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 EEB06734.1 - 0.00089 18.3 0.2 0.0023 16.9 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 EEB06734.1 - 0.019 15.3 25.9 0.49 10.7 12.2 2.5 2 0 0 2 2 2 0 C1 domain Methyltrans_RNA PF04452.14 EEB06734.1 - 0.032 13.6 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase DUF5384 PF17358.2 EEB06734.1 - 0.038 14.0 0.2 0.084 12.9 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5384) Endotoxin_C2 PF18449.1 EEB06734.1 - 0.06 13.7 1.0 0.46 10.9 0.1 2.4 1 1 1 2 2 2 0 Delta endotoxin THOC7 PF05615.13 EEB06734.1 - 1.1 9.5 7.3 8.1 6.7 0.5 3.6 3 0 0 3 3 3 0 Tho complex subunit 7 DUF4452 PF14618.6 EEB06735.1 - 3.4e-15 56.3 0.5 4e-15 56.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) IBN_N PF03810.19 EEB06736.1 - 3e-10 39.9 1.1 1.1e-09 38.0 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EEB06736.1 - 4.2e-09 35.7 0.7 0.0011 17.8 0.0 3.4 3 0 0 3 3 3 2 Cse1 CAS_CSE1 PF03378.15 EEB06736.1 - 0.00048 18.7 1.5 0.00048 18.7 1.5 2.9 1 1 2 3 3 3 1 CAS/CSE protein, C-terminus Xpo1 PF08389.12 EEB06736.1 - 0.0035 17.4 4.9 0.042 13.9 0.5 4.5 3 2 1 4 4 4 1 Exportin 1-like protein Tti2 PF10521.9 EEB06736.1 - 0.03 13.9 0.1 0.1 12.1 0.1 1.9 1 0 0 1 1 1 0 Tti2 family PC_rep PF01851.22 EEB06736.1 - 0.055 13.9 1.1 2.7 8.6 0.1 3.9 3 0 0 3 3 3 0 Proteasome/cyclosome repeat Metallophos PF00149.28 EEB06737.2 - 2.7e-36 126.0 0.2 3.5e-36 125.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEB06737.2 - 0.074 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CLP1_P PF16575.5 EEB06738.1 - 1.7e-36 125.8 0.0 2.7e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EEB06738.1 - 7.3e-32 109.5 0.0 1.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EEB06738.1 - 1.9e-31 108.9 0.0 3.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EEB06738.1 - 0.0025 17.6 0.0 0.0079 16.0 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EEB06738.1 - 0.0048 17.0 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_35 PF14516.6 EEB06738.1 - 0.0051 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.10 EEB06738.1 - 0.057 12.9 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EEB06738.1 - 0.078 13.0 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 EEB06738.1 - 0.097 12.2 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EEB06738.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EEB06738.1 - 0.2 11.9 0.0 0.58 10.4 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SH3_1 PF00018.28 EEB06739.1 - 2.2e-29 100.8 0.0 3e-14 52.4 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EEB06739.1 - 5.4e-17 61.4 0.2 3e-09 36.6 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EEB06739.1 - 3.6e-15 55.4 0.1 5.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EEB06739.1 - 1.3e-11 44.5 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 EEB06739.1 - 0.00026 20.9 0.1 0.00051 19.9 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF2417 PF10329.9 EEB06740.1 - 1.2e-48 165.6 3.3 1.7e-48 165.1 3.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.7 EEB06740.1 - 1.4e-07 32.4 1.1 1.4e-07 32.4 1.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEB06740.1 - 8.2e-05 22.4 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEB06740.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EEB06740.1 - 0.016 15.0 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBFD_NFYB_HMF PF00808.23 EEB06742.1 - 3.3e-28 97.7 0.4 4.5e-28 97.3 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB06742.1 - 4.8e-07 30.2 0.9 7.3e-07 29.6 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EEB06742.1 - 0.00021 21.4 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EEB06742.1 - 0.0042 17.1 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PAN_3 PF08277.12 EEB06742.1 - 0.028 14.2 0.4 0.045 13.6 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.13 EEB06742.1 - 0.03 14.3 0.1 0.051 13.6 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated tRNA-synt_2c PF01411.19 EEB06743.1 - 8.8e-220 730.9 0.0 1.4e-219 730.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EEB06743.1 - 5.6e-19 68.0 0.3 1.2e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EEB06743.1 - 2.2e-16 60.5 0.7 4.3e-16 59.6 0.7 1.5 1 0 0 1 1 1 1 DHHA1 domain HVSL PF09749.9 EEB06744.2 - 3.7e-46 157.5 0.6 4.5e-46 157.3 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.25 EEB06745.1 - 1.6e-60 204.7 0.0 1.8e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06745.1 - 6.2e-20 71.6 0.0 8.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB06745.1 - 5.9e-07 29.7 0.2 1.9e-05 24.7 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEB06745.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EEB06745.1 - 0.023 14.3 0.2 0.045 13.3 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EEB06745.1 - 0.032 13.6 0.2 0.065 12.6 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P53_tetramer PF07710.11 EEB06745.1 - 0.036 13.4 0.7 2 7.8 0.0 2.7 3 0 0 3 3 3 0 P53 tetramerisation motif DUF2384 PF09722.10 EEB06745.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) ANAPC_CDC26 PF10471.9 EEB06747.1 - 7.9e-11 42.6 0.3 1.1e-10 42.2 0.3 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Cation_efflux PF01545.21 EEB06748.1 - 7.1e-49 166.3 5.3 9.9e-49 165.8 5.3 1.2 1 0 0 1 1 1 1 Cation efflux family Sin3a_C PF16879.5 EEB06749.2 - 1.7e-57 195.3 2.9 1.7e-57 195.3 2.9 3.1 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EEB06749.2 - 6.6e-38 128.7 0.1 1.7e-37 127.4 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EEB06749.2 - 0.005 17.0 12.2 0.96 9.6 1.0 4.6 3 1 1 4 4 4 2 Paired amphipathic helix repeat Fib_alpha PF08702.10 EEB06749.2 - 0.24 11.6 1.3 2.6 8.2 0.1 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 EEB06750.1 - 1.5e-75 254.0 0.4 2.4e-75 253.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06750.1 - 1.7e-42 145.5 0.0 2.7e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EEB06750.1 - 2e-32 111.1 0.3 1.3e-15 57.3 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EEB06750.1 - 1.3e-06 28.0 0.0 1.4e-05 24.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB06750.1 - 6.6e-05 21.9 0.0 0.00016 20.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EEB06750.1 - 0.0009 18.3 0.2 0.0015 17.5 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEB06750.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4524 PF15025.6 EEB06750.1 - 0.0099 15.6 0.1 0.21 11.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4524) Kdo PF06293.14 EEB06750.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LETM1 PF07766.13 EEB06751.2 - 5.2e-97 324.4 0.2 7.2e-97 323.9 0.2 1.2 1 0 0 1 1 1 1 LETM1-like protein ORC6 PF05460.13 EEB06751.2 - 0.0012 18.3 1.0 0.0023 17.2 1.0 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF155 PF02582.14 EEB06751.2 - 0.066 13.3 0.5 0.22 11.6 0.4 1.8 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 LMP PF04778.12 EEB06751.2 - 0.1 12.5 1.8 0.19 11.6 1.8 1.4 1 0 0 1 1 1 0 LMP repeated region MutS_V PF00488.21 EEB06752.1 - 3.9e-71 239.0 0.1 3.9e-71 239.0 0.1 2.2 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.18 EEB06752.1 - 2.5e-36 125.7 7.6 7e-36 124.2 7.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEB06752.1 - 8.7e-19 67.8 0.0 2.4e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EEB06752.1 - 7.7e-12 45.7 0.1 4.1e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II ABC_tran PF00005.27 EEB06752.1 - 0.051 14.1 0.4 4.4 7.8 0.0 3.2 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 EEB06752.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EEB06752.1 - 0.058 13.4 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EEB06752.1 - 0.11 12.1 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEB06752.1 - 0.33 11.4 7.1 0.4 11.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain DASH_Duo1 PF08651.10 EEB06752.1 - 1.1 9.1 3.8 1.1 9.0 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 TAFII55_N PF04658.13 EEB06753.1 - 8.5e-56 188.1 0.3 8.5e-56 188.1 0.3 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 EEB06753.1 - 0.014 14.8 13.5 0.019 14.3 13.5 1.2 1 0 0 1 1 1 0 BUD22 DUF3504 PF12012.8 EEB06753.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) NusB PF01029.18 EEB06753.1 - 2.5 8.3 6.2 1.2 9.4 3.7 1.7 2 0 0 2 2 2 0 NusB family YqfQ PF14181.6 EEB06753.1 - 3.1 8.0 7.7 6.1 7.0 7.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 EEB06753.1 - 8.8 4.5 16.0 11 4.1 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Adaptin_N PF01602.20 EEB06754.1 - 3.9e-113 378.8 8.2 4.8e-113 378.5 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EEB06754.1 - 3.3e-20 72.4 0.0 3.3e-20 72.4 0.0 2.2 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 EEB06754.1 - 0.71 9.9 9.4 1.6 8.7 0.5 4.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 cwf18 PF08315.12 EEB06755.1 - 2.1e-35 122.4 8.2 2.7e-35 122.0 8.2 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Ribosomal_S8e PF01201.22 EEB06756.1 - 3.1e-48 163.4 3.3 3.1e-48 163.4 3.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e AdoHcyase PF05221.17 EEB06756.1 - 0.062 12.4 0.5 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Ank_5 PF13857.6 EEB06757.1 - 1.7e-15 56.8 0.4 4.9e-12 45.8 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEB06757.1 - 9e-15 54.8 0.1 2.2e-07 31.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB06757.1 - 1e-11 45.2 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EEB06757.1 - 4.7e-09 36.3 0.0 8.3e-07 29.2 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EEB06757.1 - 1.2e-08 34.5 0.0 8.3e-06 25.8 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeat CPL PF08144.11 EEB06758.1 - 9.9e-39 133.0 4.4 1.2e-35 123.0 0.0 5.3 4 2 2 6 6 6 1 CPL (NUC119) domain TraD PF06412.11 EEB06758.1 - 0.00036 20.3 0.4 0.49 10.3 0.0 3.0 2 0 0 2 2 2 2 Conjugal transfer protein TraD LAP1C PF05609.12 EEB06758.1 - 0.015 14.4 12.8 0.031 13.4 12.8 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ldh_1_C PF02866.18 EEB06758.1 - 0.028 14.4 0.1 0.07 13.1 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain BSP_II PF05432.11 EEB06758.1 - 0.88 9.2 26.4 1.4 8.5 26.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EEB06758.1 - 1.4 7.0 34.5 2.4 6.2 34.5 1.3 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 EEB06758.1 - 5 7.1 40.9 1.2 9.1 37.4 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 EEB06758.1 - 6.2 6.2 39.9 11 5.3 39.9 1.4 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 EEB06758.1 - 6.9 6.3 28.0 13 5.4 28.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Formyl_trans_N PF00551.19 EEB06759.1 - 9.1e-46 155.9 0.2 1e-45 155.7 0.2 1.0 1 0 0 1 1 1 1 Formyl transferase PCSK9_C2 PF18464.1 EEB06759.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Peptidase_M41 PF01434.18 EEB06761.2 - 4.2e-61 206.1 0.3 6.8e-61 205.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEB06761.2 - 3.5e-42 144.0 0.0 8.7e-42 142.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB06761.2 - 3.4e-08 33.2 0.0 6.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EEB06761.2 - 1.4e-06 28.6 0.3 0.011 16.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 EEB06761.2 - 2.6e-05 23.6 0.0 5.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EEB06761.2 - 7.7e-05 22.7 0.0 0.00022 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB06761.2 - 9.9e-05 22.8 4.1 0.0017 18.8 0.1 3.0 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EEB06761.2 - 0.00023 21.0 0.0 0.00073 19.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EEB06761.2 - 0.00097 18.6 1.2 0.012 15.1 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EEB06761.2 - 0.0042 17.0 1.9 0.17 11.8 0.1 3.1 3 0 0 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 EEB06761.2 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EEB06761.2 - 0.0048 17.4 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEB06761.2 - 0.0052 16.4 1.2 0.21 11.1 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EEB06761.2 - 0.0065 16.7 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EEB06761.2 - 0.014 15.5 0.0 0.065 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EEB06761.2 - 0.023 14.8 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EEB06761.2 - 0.033 13.3 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EEB06761.2 - 0.046 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EEB06761.2 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.6 EEB06761.2 - 0.16 11.6 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase M50B-like ATPase PF06745.13 EEB06761.2 - 0.2 11.0 0.1 0.71 9.2 0.0 1.8 2 0 0 2 2 2 0 KaiC ATP-synt_D PF01813.17 EEB06762.1 - 2.5e-66 223.3 4.9 2.5e-66 223.3 4.9 2.5 2 1 0 2 2 2 1 ATP synthase subunit D EXOSC1 PF10447.9 EEB06763.1 - 1.5e-19 70.6 3.6 3.8e-13 50.0 0.4 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EEB06763.1 - 0.016 15.0 0.8 0.053 13.3 0.8 2.0 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region LSM PF01423.22 EEB06764.1 - 3.9e-18 64.9 0.1 5.3e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain Epimerase PF01370.21 EEB06765.1 - 1.9e-06 27.6 0.2 9.3e-06 25.3 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEB06765.1 - 1.4e-05 25.0 0.0 0.00021 21.2 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EEB06765.1 - 6.8e-05 22.1 0.0 0.002 17.3 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 EEB06765.1 - 0.00011 21.8 0.0 0.00036 20.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EEB06765.1 - 0.00018 20.6 0.0 0.00067 18.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EEB06765.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EEB06765.1 - 0.0055 17.0 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EEB06765.1 - 0.019 14.5 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NdhO PF11910.8 EEB06765.1 - 0.031 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O LpxI_N PF17930.1 EEB06765.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain GDP_Man_Dehyd PF16363.5 EEB06765.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EEB06765.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 KR domain WD40 PF00400.32 EEB06766.2 - 3.9e-14 52.8 3.9 0.00039 21.2 0.2 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06766.2 - 6.2e-11 42.4 1.2 9e-05 22.7 0.0 4.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEB06766.2 - 0.00016 21.4 0.0 0.13 11.8 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EEB06766.2 - 0.0026 17.6 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 PQQ enzyme repeat Nucleoporin_N PF08801.11 EEB06766.2 - 0.0074 15.1 0.1 0.071 11.8 0.0 2.2 3 0 0 3 3 3 1 Nup133 N terminal like NfeD PF01957.18 EEB06766.2 - 0.033 14.6 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding RNB PF00773.19 EEB06767.2 - 3.1e-50 171.4 0.4 4.6e-50 170.8 0.4 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EEB06767.2 - 1.1e-22 79.8 0.0 2.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EEB06767.2 - 6e-09 36.1 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 EEB06767.2 - 0.00035 20.3 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EEB06767.2 - 0.00056 19.8 0.0 0.014 15.4 0.0 2.8 2 1 1 3 3 3 1 S1 domain OB_RNB PF08206.11 EEB06767.2 - 0.035 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain CBFD_NFYB_HMF PF00808.23 EEB06768.1 - 4.6e-13 49.3 0.9 5.8e-13 48.9 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB06768.1 - 2.9e-09 37.4 0.8 3.1e-09 37.3 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EEB06768.1 - 0.0078 16.2 0.6 0.015 15.3 0.6 1.5 1 1 1 2 2 2 1 Transcription initiation factor IID, 18kD subunit PUFD PF16553.5 EEB06768.1 - 0.025 14.7 0.2 0.028 14.6 0.2 1.1 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain DUF5480 PF17576.2 EEB06768.1 - 0.05 13.6 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5480) TAF4 PF05236.14 EEB06768.1 - 0.056 13.2 0.4 0.064 13.0 0.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NAD_Gly3P_dh_N PF01210.23 EEB06768.1 - 0.068 13.2 0.2 0.072 13.1 0.2 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TFIID_30kDa PF03540.13 EEB06768.1 - 0.081 12.9 0.4 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Glucosamine_iso PF01182.20 EEB06769.1 - 2.7e-69 233.5 0.2 3.2e-69 233.3 0.2 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAM110_C PF14160.6 EEB06769.1 - 0.057 14.5 0.4 0.18 12.9 0.0 1.9 2 0 0 2 2 2 0 Centrosome-associated C terminus Pkinase PF00069.25 EEB06770.1 - 6.7e-74 248.6 0.0 7.6e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06770.1 - 1.2e-35 123.0 0.0 1.5e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06770.1 - 0.0088 15.4 0.0 0.031 13.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEB06770.1 - 0.015 14.2 0.0 0.038 12.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EEB06770.1 - 0.02 14.8 0.1 0.052 13.5 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEB06770.1 - 0.031 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Acetyltransf_1 PF00583.25 EEB06771.2 - 5.2e-12 46.0 0.0 7.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB06771.2 - 2.8e-08 33.8 0.0 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB06771.2 - 1.1e-07 32.2 0.0 2.3e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB06771.2 - 0.00024 21.0 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EEB06771.2 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EEB06771.2 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Ribosomal_L11_N PF03946.14 EEB06772.1 - 3.7e-22 77.9 0.2 5.8e-22 77.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EEB06772.1 - 5.5e-18 65.2 0.6 3.2e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 EEB06772.1 - 0.055 13.3 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region TPR_2 PF07719.17 EEB06773.1 - 1.9e-16 58.8 34.3 0.031 14.4 2.1 12.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06773.1 - 4.9e-14 51.3 23.8 8.8e-05 22.4 0.8 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06773.1 - 1.3e-13 51.2 24.9 0.00033 21.1 0.0 8.9 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06773.1 - 2.6e-12 46.5 19.1 0.014 16.2 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06773.1 - 1.4e-09 38.1 29.2 0.018 15.3 0.5 8.9 7 3 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06773.1 - 1.1e-08 34.4 23.4 0.043 13.9 0.8 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06773.1 - 1.3e-08 34.3 36.3 0.0053 16.5 1.1 10.5 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06773.1 - 8.1e-07 29.3 20.9 0.28 11.9 0.9 8.5 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EEB06773.1 - 7.4e-05 22.5 20.4 0.039 13.8 2.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB06773.1 - 8.7e-05 22.6 15.0 0.07 13.3 0.1 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06773.1 - 0.00065 20.3 24.3 1.7 9.3 0.0 7.6 9 1 0 9 9 8 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EEB06773.1 - 0.035 14.1 0.9 6.6 6.7 0.0 3.8 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 EEB06773.1 - 0.094 13.1 14.9 1.8 9.1 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB06773.1 - 0.44 10.8 24.4 0.21 11.8 0.3 7.1 8 1 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EEB06773.1 - 2 8.2 23.0 1.6 8.5 0.6 6.8 7 1 1 8 8 8 0 TPR repeat Ribosomal_L2_C PF03947.18 EEB06775.1 - 9.3e-50 168.1 0.6 2e-49 167.0 0.6 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEB06775.1 - 1.6e-26 92.1 0.2 4.8e-26 90.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain SH3_15 PF18346.1 EEB06775.1 - 0.12 12.8 0.1 0.62 10.4 0.0 2.3 1 1 1 2 2 2 0 Mind bomb SH3 repeat domain NCBP3 PF10309.9 EEB06776.2 - 1.7e-17 63.0 0.0 2.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 SMC_N PF02463.19 EEB06777.1 - 2.1e-64 217.0 3.8 2.9e-64 216.5 3.8 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEB06777.1 - 7.7e-30 103.6 0.3 2.2e-28 98.9 0.1 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEB06777.1 - 1.3e-15 58.0 2.5 7e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEB06777.1 - 3.5e-15 57.0 6.2 3.5e-15 57.0 6.2 5.6 4 1 1 5 5 4 1 AAA domain AAA_29 PF13555.6 EEB06777.1 - 1.2e-06 28.2 0.0 3.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 EEB06777.1 - 3.8e-05 23.1 19.7 3.8e-05 23.1 19.7 6.4 4 1 2 6 6 6 2 Growth-arrest specific micro-tubule binding SbcCD_C PF13558.6 EEB06777.1 - 0.015 15.5 0.0 0.05 13.8 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EEB06777.1 - 0.018 15.5 0.0 0.018 15.5 0.0 5.9 4 3 0 4 4 2 0 ABC transporter AAA_15 PF13175.6 EEB06777.1 - 0.12 12.1 70.2 0.23 11.1 4.4 4.8 2 2 1 3 3 2 0 AAA ATPase domain AAA_27 PF13514.6 EEB06777.1 - 0.2 11.2 0.0 0.2 11.2 0.0 5.7 6 1 1 7 7 7 0 AAA domain Sugarporin_N PF11471.8 EEB06777.1 - 0.57 10.2 5.3 14 5.7 1.2 3.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ACP_PD PF04336.12 EEB06777.1 - 2.7 8.5 10.1 3.3 8.2 0.1 5.2 3 2 2 5 5 5 0 Acyl carrier protein phosphodiesterase Bac_RepA_C PF18008.1 EEB06777.1 - 9.8 6.6 8.6 4.9 7.6 0.0 4.5 4 0 0 4 4 3 0 Replication initiator protein A C-terminal domain XPG_N PF00752.17 EEB06778.1 - 1.4e-31 109.0 0.0 2.4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EEB06778.1 - 3.2e-19 69.1 0.0 6.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region ELYS PF13934.6 EEB06779.1 - 6.3e-52 176.7 5.2 9.1e-52 176.2 5.2 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF3368 PF11848.8 EEB06779.1 - 0.00055 19.7 0.1 2 8.3 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3368) TPR_2 PF07719.17 EEB06779.1 - 0.73 10.1 3.4 78 3.8 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Filamin PF00630.19 EEB06780.1 - 0.053 14.3 0.4 5.1 8.0 0.0 3.7 4 0 0 4 4 4 0 Filamin/ABP280 repeat Glyco_hydro_72 PF03198.14 EEB06781.1 - 3.1e-128 427.5 9.5 4e-128 427.1 9.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EEB06781.1 - 9.2e-15 55.1 4.1 9.2e-15 55.1 4.1 2.3 3 0 0 3 3 3 1 X8 domain CAF1 PF04857.20 EEB06782.1 - 3.1e-46 158.0 0.0 1.1e-45 156.3 0.0 1.7 1 1 0 1 1 1 1 CAF1 family ribonuclease DUF2564 PF10819.8 EEB06782.1 - 0.075 13.4 0.1 0.49 10.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) Pkinase PF00069.25 EEB06783.1 - 9.2e-75 251.4 0.0 1.1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06783.1 - 1e-46 159.4 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06783.1 - 7.7e-10 38.5 0.0 7.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEB06783.1 - 5.4e-05 22.6 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB06783.1 - 0.00075 18.4 0.1 0.00096 18.0 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EEB06783.1 - 0.0022 17.6 0.3 0.035 13.7 0.0 2.2 2 1 1 3 3 3 1 RIO1 family Haspin_kinase PF12330.8 EEB06783.1 - 0.005 15.8 0.1 0.0078 15.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EEB06783.1 - 0.0052 16.4 0.5 0.094 12.3 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EEB06783.1 - 0.041 13.4 0.1 0.082 12.4 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EEB06783.1 - 0.075 13.0 0.5 0.64 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.9 EEB06784.2 - 3.7e-64 215.6 6.5 4.1e-64 215.5 6.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.6 EEB06784.2 - 0.0046 16.7 0.2 0.0057 16.4 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase toxin 2 SprT-like PF10263.9 EEB06784.2 - 0.4 10.6 7.0 0.16 11.8 2.9 2.0 1 1 1 2 2 2 0 SprT-like family UPF0113_N PF17833.1 EEB06785.1 - 6.3e-33 113.2 0.1 8.9e-33 112.7 0.1 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EEB06785.1 - 1.3e-26 92.6 0.0 2.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain DUF1825 PF08855.10 EEB06785.1 - 0.047 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) PUA PF01472.20 EEB06785.1 - 0.087 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain SRP72 PF08492.12 EEB06786.1 - 2e-11 44.2 5.4 4.6e-11 43.0 5.4 1.5 1 0 0 1 1 1 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 EEB06786.1 - 5.5e-07 29.6 7.3 2.6e-06 27.4 0.3 3.2 3 1 0 3 3 3 1 Putative TPR-like repeat ANAPC3 PF12895.7 EEB06786.1 - 3.8e-05 23.8 4.4 2.9 8.2 0.1 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EEB06786.1 - 0.0019 18.8 2.6 28 5.9 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06786.1 - 0.016 15.7 9.3 1.7 9.2 0.5 4.7 3 2 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 EEB06786.1 - 0.021 14.5 0.6 0.062 13.0 0.2 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 EEB06786.1 - 0.045 14.1 1.0 2.9 8.3 0.1 3.7 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06786.1 - 0.08 13.6 11.5 8.4 7.3 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 EEB06786.1 - 0.11 12.2 2.3 14 5.5 0.1 3.6 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_12 PF13424.6 EEB06786.1 - 0.16 12.3 5.3 0.31 11.4 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEB06786.1 - 0.72 9.8 3.8 2.1 8.4 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06786.1 - 7.1 7.4 7.1 44 4.8 0.3 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Ferrochelatase PF00762.19 EEB06787.2 - 1.4e-98 329.9 0.0 1.7e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase SLC35F PF06027.12 EEB06788.1 - 1.2e-113 379.6 26.4 1.4e-113 379.3 26.4 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EEB06788.1 - 1.5e-12 47.1 10.1 2.8e-12 46.2 10.1 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EEB06788.1 - 3e-07 30.7 34.7 3.9e-05 23.9 12.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1689 PF07954.11 EEB06788.1 - 0.42 11.0 2.4 0.35 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) RRM_1 PF00076.22 EEB06789.2 - 2.8e-16 59.1 0.1 1.1e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H-assoc PF13902.6 EEB06790.1 - 0.0048 17.3 0.1 0.0083 16.5 0.1 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain Gln-synt_C PF00120.24 EEB06791.1 - 2.6e-49 168.1 0.0 3.2e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain But2 PF09792.9 EEB06792.1 - 3.5e-21 76.1 3.4 3.5e-21 76.1 3.4 2.0 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Reticulon PF02453.17 EEB06793.1 - 6.5e-29 100.9 5.5 1.1e-28 100.1 5.0 1.6 2 0 0 2 2 2 1 Reticulon adh_short PF00106.25 EEB06795.1 - 5.2e-52 176.2 1.7 6.1e-52 175.9 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB06795.1 - 5.5e-33 114.5 1.1 6.5e-33 114.2 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB06795.1 - 1.8e-15 57.3 0.1 2.3e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEB06795.1 - 0.00014 21.1 1.8 0.00025 20.3 1.8 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EEB06795.1 - 0.037 13.8 0.5 0.077 12.8 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GTP_EFTU PF00009.27 EEB06796.2 - 2.5e-54 183.8 0.5 3.7e-54 183.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEB06796.2 - 1.5e-36 125.1 0.0 3.4e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEB06796.2 - 2.3e-14 53.6 7.1 6.9e-14 52.0 1.7 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB06796.2 - 0.00042 20.4 0.2 0.01 15.9 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EEB06796.2 - 0.025 14.5 0.8 0.092 12.7 0.8 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 RRM_1 PF00076.22 EEB06797.1 - 2e-14 53.2 0.0 2.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEB06797.1 - 0.0053 16.8 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Ribosomal_L34e PF01199.18 EEB06798.1 - 4e-42 142.4 1.8 5.2e-42 142.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e zf-C3HC4 PF00097.25 EEB06799.1 - 5.1e-06 26.3 7.7 1.7e-05 24.6 7.8 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB06799.1 - 1.7e-05 25.0 7.6 2.8e-05 24.4 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EEB06799.1 - 3.8e-05 23.5 6.7 7.1e-05 22.7 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEB06799.1 - 0.0002 21.3 5.9 0.00042 20.3 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEB06799.1 - 0.00029 20.6 7.9 0.0012 18.7 7.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB06799.1 - 0.00036 20.6 4.4 0.00036 20.6 4.4 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEB06799.1 - 0.00039 20.2 9.0 0.00092 19.0 9.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEB06799.1 - 0.00072 19.4 8.7 0.0012 18.6 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEB06799.1 - 0.0016 18.7 3.9 0.0027 17.9 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EEB06799.1 - 0.11 12.3 2.2 0.21 11.4 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4248 PF14053.6 EEB06799.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) INSC_LBD PF16748.5 EEB06799.1 - 0.2 11.1 0.7 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 Inscuteable LGN-binding domain zf-RING_11 PF17123.5 EEB06799.1 - 1.5 8.6 4.8 3 7.7 4.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 EEB06800.1 - 1.2e-73 247.8 0.0 1.6e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06800.1 - 9.7e-31 107.0 0.0 1.8e-30 106.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB06800.1 - 1.8e-05 24.2 0.6 0.012 14.9 0.2 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EEB06800.1 - 0.0018 17.9 4.6 0.0024 17.5 2.9 2.1 2 1 0 2 2 2 1 RIO1 family Kdo PF06293.14 EEB06800.1 - 0.0093 15.3 1.7 0.024 14.0 1.2 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB06800.1 - 0.022 13.6 0.0 0.052 12.3 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EEB06800.1 - 0.06 13.0 0.3 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB06800.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SPT_ssu-like PF11779.8 EEB06801.1 - 5.9e-14 51.4 3.3 8.1e-14 51.0 3.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Glyco_hydro_47 PF01532.20 EEB06802.1 - 6.7e-111 371.4 0.0 9.9e-111 370.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EEB06802.1 - 0.17 10.4 0.0 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Pribosyltran PF00156.27 EEB06803.1 - 9.3e-18 64.2 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEB06803.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EEB06803.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Metallophos PF00149.28 EEB06804.2 - 9.8e-09 36.0 1.2 1.7e-08 35.2 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GPI-anchored PF10342.9 EEB06805.1 - 1.1e-12 48.5 1.3 1.1e-12 48.5 1.3 3.0 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_transf_20 PF00982.21 EEB06806.1 - 3e-159 530.7 0.7 5.3e-158 526.6 0.7 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEB06806.1 - 9.2e-80 267.1 0.0 1.4e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EEB06806.1 - 8e-05 22.5 0.0 0.23 11.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PIP5K PF01504.18 EEB06807.1 - 3.6e-98 328.2 0.0 6.2e-98 327.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UL42 PF17638.2 EEB06807.1 - 0.35 10.8 4.7 3.1 7.8 0.3 2.4 2 0 0 2 2 2 0 HCMV UL42 SEO_N PF14576.6 EEB06808.2 - 0.086 12.0 1.8 0.064 12.4 0.4 1.5 2 0 0 2 2 2 0 Sieve element occlusion N-terminus polyprenyl_synt PF00348.17 EEB06809.1 - 7.5e-14 51.4 0.1 1.7e-13 50.2 0.1 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EEB06809.1 - 0.00045 19.9 0.5 0.00077 19.1 0.5 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Rossmann-like PF10727.9 EEB06809.1 - 0.14 12.1 0.7 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Rossmann-like domain COQ9 PF08511.11 EEB06810.1 - 5.4e-25 87.0 0.3 1.3e-24 85.8 0.1 1.7 2 0 0 2 2 2 1 COQ9 ER PF01133.17 EEB06811.1 - 1.5e-13 50.6 0.2 2.1e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S10 PF00450.22 EEB06812.1 - 1.1e-124 417.1 0.2 1.7e-124 416.4 0.2 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Aldo_ket_red PF00248.21 EEB06813.1 - 2.4e-38 132.0 0.0 3.2e-37 128.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LSM PF01423.22 EEB06814.1 - 8e-19 67.1 0.0 8.8e-19 67.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain p450 PF00067.22 EEB06815.1 - 0.013 14.2 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Mito_carr PF00153.27 EEB06816.1 - 2e-55 184.7 5.1 3.1e-22 78.3 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Histone_H2A_C PF16211.5 EEB06817.1 - 6.6e-19 67.4 0.9 1.1e-18 66.6 0.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EEB06817.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEB06817.1 - 7.8e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HIT PF01230.23 EEB06817.1 - 0.079 13.7 0.0 0.11 13.3 0.0 1.3 1 1 0 1 1 1 0 HIT domain HSP70 PF00012.20 EEB06818.1 - 2.7e-234 778.9 11.0 3e-234 778.7 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB06818.1 - 8.9e-18 64.2 1.5 8.2e-17 61.0 0.6 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EEB06818.1 - 0.00029 20.2 0.3 0.00084 18.7 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.11 EEB06818.1 - 0.01 15.1 0.7 0.032 13.5 0.0 2.1 2 0 0 2 2 2 0 StbA protein Zincin_2 PF10103.9 EEB06818.1 - 0.031 13.6 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase RPA PF10134.9 EEB06818.1 - 0.034 13.6 0.4 0.093 12.2 0.4 1.7 1 0 0 1 1 1 0 Replication initiator protein A FGGY_C PF02782.16 EEB06818.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EEB06818.1 - 0.055 13.9 7.9 3 8.3 1.7 4.1 2 1 0 2 2 2 0 Cell division protein FtsA IMD PF08397.11 EEB06818.1 - 0.37 10.1 7.1 0.81 9.0 7.1 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain DDR PF08841.10 EEB06818.1 - 0.53 9.2 5.7 0.28 10.1 0.1 2.9 3 1 1 4 4 4 0 Diol dehydratase reactivase ATPase-like domain TRAF_BIRC3_bd PF16673.5 EEB06818.1 - 3.9 7.3 5.6 36 4.2 2.3 3.3 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Pyrophosphatase PF00719.19 EEB06819.1 - 3.8e-52 176.3 0.0 5.1e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase APG6 PF04111.12 EEB06820.1 - 1.8e-64 217.0 0.3 3.9e-64 215.9 0.0 1.7 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EEB06820.1 - 1.3e-23 84.0 16.7 1.3e-23 84.0 16.7 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region Rpr2 PF04032.16 EEB06820.1 - 0.086 13.1 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2334 PF10096.9 EEB06820.1 - 0.089 12.4 0.2 0.81 9.3 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) TBCC_N PF16752.5 EEB06820.1 - 2.1 8.8 10.2 1.5 9.3 5.8 2.5 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain KLRAQ PF10205.9 EEB06820.1 - 2.5 8.4 9.9 3.3 8.0 3.4 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein GNAT_acetyltr_2 PF13718.6 EEB06821.1 - 3e-98 327.8 0.1 9.5e-98 326.1 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EEB06821.1 - 3.5e-85 285.5 5.4 5.4e-85 284.8 5.4 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EEB06821.1 - 1.2e-65 220.6 0.0 3.1e-65 219.3 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 EEB06821.1 - 2.1e-35 120.5 0.1 6.8e-35 118.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 EEB06821.1 - 0.00094 19.4 0.0 0.023 14.9 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family AAA_22 PF13401.6 EEB06821.1 - 0.01 16.1 0.0 0.91 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain CobA_CobO_BtuR PF02572.15 EEB06821.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Acetyltransf_7 PF13508.7 EEB06821.1 - 0.089 13.2 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DprA_WH PF17782.1 EEB06821.1 - 0.12 12.5 1.9 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 DprA winged helix domain SNF2_N PF00176.23 EEB06822.1 - 3.7e-52 177.2 0.1 9.5e-52 175.8 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB06822.1 - 2.9e-19 69.5 0.2 1.5e-17 63.9 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB06822.1 - 6.6e-13 49.0 0.0 2.1e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ORC6 PF05460.13 EEB06822.1 - 1.5 8.0 15.7 0.99 8.6 12.6 1.9 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.6 EEB06822.1 - 3.9 7.1 8.2 16 5.1 8.2 2.1 1 0 0 1 1 1 0 FAM176 family Tim17 PF02466.19 EEB06823.1 - 8.7e-32 109.8 6.3 1.2e-31 109.4 6.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 EEB06823.1 - 0.029 14.5 6.6 0.052 13.7 2.0 2.4 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III PALP PF00291.25 EEB06824.1 - 4.1e-66 223.4 0.0 4.8e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Putative_PNPOx PF01243.20 EEB06825.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EEB06825.1 - 1.6e-17 63.3 2.3 2.2e-17 62.8 0.8 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EEB06825.1 - 0.00048 20.7 0.0 0.00087 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4662 PF15578.6 EEB06825.1 - 0.097 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) KdpC PF02669.15 EEB06825.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain PPR_2 PF13041.6 EEB06826.1 - 1e-29 102.4 20.7 3e-12 46.5 0.0 11.2 7 3 6 13 13 13 6 PPR repeat family PPR_3 PF13812.6 EEB06826.1 - 2.3e-29 101.2 0.6 1e-06 28.7 0.0 7.6 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 EEB06826.1 - 2.1e-26 90.3 21.0 5.6e-05 23.1 0.1 13.3 15 1 0 15 15 15 5 PPR repeat PPR_1 PF12854.7 EEB06826.1 - 7.2e-23 80.0 7.3 3.3e-06 26.7 0.0 10.1 11 0 0 11 11 11 4 PPR repeat PPR_long PF17177.4 EEB06826.1 - 9.6e-21 74.1 11.2 2.8e-08 33.4 0.0 5.8 3 2 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EEB06826.1 - 0.00025 20.9 0.9 1.6 8.6 0.0 5.4 4 1 0 5 5 5 1 Mitochondrial ATPase expression RPM2 PF08579.11 EEB06826.1 - 0.00042 20.7 0.9 0.0076 16.6 0.1 3.5 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) Prefoldin_3 PF13758.6 EEB06826.1 - 0.05 13.7 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Prefoldin subunit Glyco_hydro_125 PF06824.11 EEB06827.1 - 6.3e-178 591.9 0.0 7.2e-178 591.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RNase_H2_suC PF08615.11 EEB06828.1 - 1.7e-23 83.4 0.0 2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase PF00069.25 EEB06829.1 - 2.4e-49 168.1 0.0 4.2e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06829.1 - 1.9e-37 129.0 0.0 8.3e-37 126.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EEB06829.1 - 1.7e-11 44.3 0.1 4.8e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EEB06829.1 - 2.9e-07 30.1 0.0 1.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEB06829.1 - 0.052 12.9 0.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLTH PF10607.9 EEB06830.1 - 1.2e-23 83.7 1.3 1.4e-23 83.4 1.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EEB06830.1 - 0.0041 17.0 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 LisH BHD_3 PF10405.9 EEB06831.1 - 2.4e-26 91.9 0.0 1.7e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EEB06831.1 - 5.1e-25 87.9 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EEB06831.1 - 1.8e-18 66.1 1.0 6.6e-17 61.1 0.2 2.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EEB06831.1 - 1.8e-08 35.2 3.2 7.3e-07 30.1 3.2 3.2 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 2 Cellulase PF00150.18 EEB06832.1 - 1.2e-12 47.9 0.4 1.2e-12 47.9 0.4 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Nod1 PF17114.5 EEB06833.1 - 3.4e-54 183.0 1.0 8.2e-54 181.7 1.0 1.7 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 AIP3 PF03915.13 EEB06833.1 - 0.015 14.4 3.4 0.046 12.8 1.1 2.5 3 0 0 3 3 3 0 Actin interacting protein 3 RST PF12174.8 EEB06833.1 - 0.068 13.1 0.1 0.64 10.0 0.2 2.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DUF5566 PF17721.1 EEB06833.1 - 0.11 12.7 8.9 0.2 11.9 8.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5566) DUF148 PF02520.17 EEB06833.1 - 0.15 12.2 5.9 3.3 7.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 FlaC_arch PF05377.11 EEB06833.1 - 0.55 10.7 3.6 28 5.2 0.7 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mito_carr PF00153.27 EEB06834.1 - 4.1e-46 154.8 6.8 1.1e-19 70.1 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB06834.1 - 0.00035 19.8 0.5 0.00063 19.0 0.5 1.4 1 1 0 1 1 1 1 Gammaproteobacterial serine protease ATP_bind_3 PF01171.20 EEB06835.1 - 8.7e-41 139.7 0.0 1.4e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EEB06835.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF1002 PF06207.11 EEB06835.1 - 0.14 11.7 0.4 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) F-actin_cap_A PF01267.17 EEB06837.1 - 9.6e-68 228.5 3.1 1.1e-67 228.3 3.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Sdh5 PF03937.16 EEB06838.1 - 2.9e-26 91.2 0.5 4.4e-26 90.6 0.5 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Peptidase_M24 PF00557.24 EEB06839.2 - 2.6e-50 171.0 0.1 4.1e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEB06839.2 - 2e-31 108.3 0.0 3.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Transglut_core2 PF13369.6 EEB06839.2 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily TTL PF03133.15 EEB06840.1 - 1.9e-60 204.5 0.9 3.2e-60 203.8 0.9 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EEB06840.1 - 0.00046 19.5 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp WD40 PF00400.32 EEB06841.1 - 6.4e-09 36.3 14.1 0.00021 22.0 0.7 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06841.1 - 7.9e-06 26.1 0.0 0.011 16.0 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EEB06841.1 - 0.0012 16.9 0.0 0.0066 14.5 0.0 1.8 1 1 1 2 2 2 1 IKI3 family Acetyltransf_1 PF00583.25 EEB06842.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB06842.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HECT PF00632.25 EEB06843.1 - 1.7e-78 264.3 0.2 4.8e-78 262.7 0.2 1.9 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1981 PF09324.10 EEB06843.1 - 0.13 12.2 4.9 0.22 11.4 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Phage_Treg PF04761.12 EEB06843.1 - 0.14 12.3 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator CDC45 PF02724.14 EEB06843.1 - 2.4 6.3 14.8 1.2 7.3 12.4 1.6 2 0 0 2 2 2 0 CDC45-like protein Zds_C PF08632.10 EEB06844.1 - 4.9e-28 96.6 2.7 4.9e-28 96.6 2.7 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pro_dh PF01619.18 EEB06845.1 - 2.4e-54 184.9 0.3 2.8e-54 184.7 0.3 1.2 1 0 0 1 1 1 1 Proline dehydrogenase P22_AR_C PF10548.9 EEB06845.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain Cyt-b5 PF00173.28 EEB06847.1 - 1e-05 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIF PF03031.18 EEB06848.1 - 2.1e-52 177.0 0.3 3.3e-52 176.4 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sas10 PF09368.10 EEB06849.1 - 3.4e-27 94.7 4.2 1.1e-26 93.0 4.2 2.0 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EEB06849.1 - 2.5e-11 44.0 0.0 1.3e-10 41.7 0.0 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Auto_anti-p27 PF06677.12 EEB06850.1 - 8.5e-16 57.8 2.4 1.5e-15 57.1 2.4 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HEAT_EZ PF13513.6 EEB06851.1 - 6.6e-19 68.0 12.7 2.2e-12 47.2 0.0 5.8 6 0 0 6 6 6 3 HEAT-like repeat HEAT PF02985.22 EEB06851.1 - 1.1e-17 62.6 10.0 9.6e-05 22.3 0.0 9.1 8 0 0 8 8 8 3 HEAT repeat IBN_N PF03810.19 EEB06851.1 - 3.1e-09 36.6 6.1 1.3e-08 34.7 0.7 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EEB06851.1 - 1e-08 35.4 9.2 0.0038 17.6 0.2 6.5 4 2 2 6 6 6 4 HEAT repeats Arm PF00514.23 EEB06851.1 - 8.9e-07 28.7 12.1 0.012 15.6 0.0 6.6 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EEB06851.1 - 8e-05 22.3 0.7 1.9 8.0 0.0 4.2 2 2 2 4 4 4 2 CLASP N terminal MMS19_C PF12460.8 EEB06851.1 - 0.00021 20.5 7.1 0.038 13.1 0.0 3.8 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal TIP120 PF08623.10 EEB06851.1 - 0.0023 17.7 2.8 0.074 12.8 0.0 3.9 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) MMS19_N PF14500.6 EEB06851.1 - 0.02 14.5 7.4 6.1 6.3 0.4 4.9 2 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 EEB06851.1 - 0.04 13.6 8.7 0.44 10.3 0.2 4.6 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 EEB06851.1 - 0.19 11.6 1.4 4.3 7.2 0.0 3.2 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal EspB PF05802.11 EEB06851.1 - 0.41 10.6 3.9 6.7 6.7 2.1 3.0 2 1 0 2 2 2 0 Enterobacterial EspB protein Pan3_PK PF18101.1 EEB06852.1 - 1.5e-32 112.4 0.2 2.4e-32 111.8 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EEB06852.1 - 0.00073 19.0 0.0 0.0095 15.3 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Methyltransf_25 PF13649.6 EEB06853.1 - 4.9e-14 52.8 0.0 8.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB06853.1 - 5.9e-14 52.2 0.0 8.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB06853.1 - 5.2e-13 49.5 0.0 8.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB06853.1 - 6.2e-13 49.3 0.0 1.2e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB06853.1 - 1.1e-11 44.7 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEB06853.1 - 0.00051 19.6 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EEB06853.1 - 0.00083 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 EEB06853.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EEB06853.1 - 0.0034 17.2 0.0 0.0092 15.9 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 EEB06853.1 - 0.0044 16.7 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EEB06853.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TRAM_LAG1_CLN8 PF03798.16 EEB06854.1 - 2.7e-39 134.9 17.6 3.6e-39 134.6 17.6 1.1 1 0 0 1 1 1 1 TLC domain DUF3169 PF11368.8 EEB06854.1 - 0.004 16.7 0.1 0.0092 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF4234 PF14018.6 EEB06854.1 - 0.4 10.8 5.7 0.61 10.3 2.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) vATP-synt_AC39 PF01992.16 EEB06855.1 - 3.5e-109 365.4 3.0 4.2e-109 365.1 3.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TPR_1 PF00515.28 EEB06856.1 - 3.6e-12 45.6 9.7 1.8e-05 24.4 2.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06856.1 - 2.1e-09 37.7 3.1 2.6e-06 27.9 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06856.1 - 2e-08 33.7 9.2 0.00056 19.8 0.6 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06856.1 - 1.7e-07 31.4 3.4 0.00011 22.4 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB06856.1 - 1.2e-05 25.9 0.0 0.0078 16.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB06856.1 - 2.1e-05 24.7 5.3 0.00042 20.5 5.2 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEB06856.1 - 2.3e-05 24.2 4.9 0.023 14.9 1.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF5113 PF17140.4 EEB06856.1 - 0.00033 20.5 0.7 0.23 11.2 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5113) TPR_11 PF13414.6 EEB06856.1 - 0.0023 17.6 3.8 0.0055 16.4 1.6 2.3 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 EEB06856.1 - 0.0063 17.2 0.3 35 5.6 0.0 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06856.1 - 0.013 15.5 1.2 0.19 11.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEB06856.1 - 0.014 15.7 0.4 0.084 13.3 0.0 2.6 2 1 2 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06856.1 - 0.03 14.9 1.1 6.9 7.5 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat SPO22 PF08631.10 EEB06856.1 - 0.088 12.3 4.2 1.2 8.5 0.4 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 EEB06856.1 - 0.1 12.6 1.3 0.26 11.3 1.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sox_N PF12444.8 EEB06857.1 - 3.5 8.8 9.9 8.9 7.5 1.7 2.4 2 0 0 2 2 2 0 Sox developmental protein N terminal Myb_DNA-binding PF00249.31 EEB06858.1 - 1e-23 83.3 0.4 2.2e-11 43.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB06858.1 - 9.3e-16 57.8 0.2 1.8e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EEB06858.1 - 0.00017 21.6 0.0 0.091 12.8 0.0 2.4 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EEB06858.1 - 0.038 14.2 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 MBA1 PF07961.11 EEB06859.1 - 6.1e-26 90.9 0.0 7.8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Choline_kinase PF01633.20 EEB06860.1 - 1.1e-53 182.0 0.0 1.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EEB06860.1 - 2.8e-07 30.7 2.0 7.9e-07 29.2 1.8 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.14 EEB06860.1 - 1.7e-05 24.4 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus RRM_1 PF00076.22 EEB06861.1 - 2e-24 85.2 0.0 1.5e-11 44.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB06861.1 - 0.0003 20.7 0.0 0.26 11.3 0.0 2.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EEB06861.1 - 0.016 15.2 0.0 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Citrate_synt PF00285.21 EEB06862.2 - 1.1e-97 327.4 0.0 1.4e-97 327.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MFS_1 PF07690.16 EEB06864.2 - 9.1e-34 116.9 54.2 7e-33 114.0 49.0 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB06864.2 - 6.5e-14 51.3 17.2 6.5e-14 51.3 17.2 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB06864.2 - 3.2e-13 49.4 11.1 3.2e-13 49.4 11.1 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter CSTF_C PF14304.6 EEB06864.2 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal MPC PF03650.13 EEB06865.2 - 3.9e-33 113.9 0.1 5e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LAB_N PF07578.11 EEB06865.2 - 0.00043 20.3 0.6 0.0012 18.9 0.1 2.0 1 1 2 3 3 3 1 Lipid A Biosynthesis N-terminal domain Sec6 PF06046.13 EEB06866.2 - 6.9e-111 371.4 9.1 6.9e-111 371.4 9.1 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EEB06866.2 - 0.0025 16.8 6.3 0.0083 15.1 6.3 1.9 1 1 0 1 1 1 1 Vps53-like, N-terminal Sec5 PF15469.6 EEB06866.2 - 0.013 15.3 1.6 0.15 11.8 1.0 3.0 1 1 0 1 1 1 0 Exocyst complex component Sec5 eIF3_subunit PF08597.10 EEB06866.2 - 0.032 14.2 1.0 0.081 12.8 0.7 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SAPI PF16560.5 EEB06866.2 - 0.09 12.4 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative mobile pathogenicity island RasGAP_C PF03836.15 EEB06866.2 - 0.22 11.7 2.2 1.1 9.4 2.2 2.2 1 1 0 1 1 1 0 RasGAP C-terminus Sds3 PF08598.11 EEB06866.2 - 3.9 7.4 10.2 0.63 10.0 1.9 3.0 2 1 1 3 3 3 0 Sds3-like ANAPC4_WD40 PF12894.7 EEB06867.1 - 3.2e-21 75.4 0.0 0.0032 17.7 0.0 6.5 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB06867.1 - 3.3e-16 59.4 7.7 0.00099 19.9 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 EEB06867.1 - 2e-06 27.8 0.0 0.015 15.2 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EEB06867.1 - 4.1e-06 26.6 0.2 4.1e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 LisH Frtz PF11768.8 EEB06867.1 - 0.00012 20.5 0.2 0.44 8.8 0.0 3.1 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF1751 PF08551.10 EEB06868.2 - 1.3e-16 61.0 4.6 1.3e-16 61.0 4.6 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EEB06868.2 - 2.4e-05 24.4 11.5 4.9e-05 23.4 11.5 1.5 1 0 0 1 1 1 1 Rhomboid family CENP-Q PF13094.6 EEB06869.1 - 2e-16 60.7 13.1 3.1e-16 60.0 13.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit NPV_P10 PF05531.12 EEB06869.1 - 0.12 12.9 2.2 0.3 11.6 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EEB06869.1 - 1.6 8.0 5.3 4.6 6.5 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EEB06869.1 - 3.6 6.4 5.6 3.9 6.3 5.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EF_assoc_1 PF08355.12 EEB06870.1 - 7.1e-27 92.8 0.7 1.4e-26 91.9 0.7 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 EEB06870.1 - 2.5e-25 88.3 0.0 1.2e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 EEB06870.1 - 3.5e-23 82.0 0.0 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EEB06870.1 - 5.4e-13 49.2 0.0 1.2e-07 31.9 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EEB06870.1 - 1.7e-07 31.6 0.0 0.024 14.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EEB06870.1 - 4e-07 30.1 0.6 0.017 15.0 0.0 4.2 4 1 0 4 4 4 1 RsgA GTPase MMR_HSR1 PF01926.23 EEB06870.1 - 9.4e-07 28.9 0.0 0.0037 17.3 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EEB06870.1 - 1.2e-06 29.0 0.0 0.026 14.9 0.1 2.5 2 1 0 2 2 2 2 AAA ATPase domain EF-hand_1 PF00036.32 EEB06870.1 - 9.6e-06 24.8 1.7 0.016 14.7 0.3 2.9 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.23 EEB06870.1 - 2e-05 24.7 1.7 0.006 16.6 0.1 2.9 3 0 0 3 3 3 1 Dynamin family EF-hand_6 PF13405.6 EEB06870.1 - 3e-05 23.6 3.5 0.0074 16.1 0.8 2.7 2 0 0 2 2 2 1 EF-hand domain DUF815 PF05673.13 EEB06870.1 - 3.4e-05 23.1 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) EF-hand_7 PF13499.6 EEB06870.1 - 4.3e-05 23.9 0.4 0.5 10.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Septin PF00735.18 EEB06870.1 - 0.00012 21.5 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 Septin NACHT PF05729.12 EEB06870.1 - 0.00013 21.9 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 EEB06870.1 - 0.00018 21.2 0.0 0.66 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 EEB06870.1 - 0.00024 21.6 0.0 0.79 10.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA PF00004.29 EEB06870.1 - 0.00029 21.3 0.0 1.2 9.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEB06870.1 - 0.00046 20.2 0.0 0.034 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EEB06870.1 - 0.00095 19.0 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EEB06870.1 - 0.0012 18.8 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EEB06870.1 - 0.0018 18.0 0.0 2.1 8.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EEB06870.1 - 0.0021 18.4 0.0 2.3 8.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_7 PF12775.7 EEB06870.1 - 0.0024 17.4 0.1 2 7.9 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region EF-hand_8 PF13833.6 EEB06870.1 - 0.0031 17.3 1.5 0.0064 16.3 0.1 2.2 2 1 1 3 3 2 1 EF-hand domain pair AAA_23 PF13476.6 EEB06870.1 - 0.0038 17.8 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.6 EEB06870.1 - 0.0038 16.6 2.0 0.0051 16.2 0.2 2.2 2 0 0 2 2 2 1 EF hand Zeta_toxin PF06414.12 EEB06870.1 - 0.006 15.9 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Arf PF00025.21 EEB06870.1 - 0.0069 15.9 0.0 0.55 9.7 0.0 3.0 3 1 0 3 3 3 1 ADP-ribosylation factor family SPARC_Ca_bdg PF10591.9 EEB06870.1 - 0.0072 16.6 1.2 14 6.0 0.1 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_18 PF13238.6 EEB06870.1 - 0.0074 16.8 0.0 0.1 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEB06870.1 - 0.012 15.2 0.0 2.6 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 EEB06870.1 - 0.014 14.8 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 EEB06870.1 - 0.014 14.2 0.1 0.95 8.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein GTP_EFTU PF00009.27 EEB06870.1 - 0.032 13.8 0.0 18 4.8 0.0 3.3 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EEB06870.1 - 0.045 13.3 0.3 20 4.7 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_28 PF13521.6 EEB06870.1 - 0.055 13.7 0.0 3.4 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EEB06870.1 - 0.07 13.3 0.1 6.5 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 EEB06870.1 - 0.076 12.7 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 EEB06870.1 - 0.084 12.6 0.2 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EEB06870.1 - 0.096 12.4 0.0 16 5.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EEB06870.1 - 0.1 12.1 0.0 9.1 5.7 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 EEB06870.1 - 0.11 12.2 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IIGP PF05049.13 EEB06870.1 - 0.15 11.1 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NB-ARC PF00931.22 EEB06870.1 - 0.17 11.1 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.23 EEB06870.1 - 0.17 10.9 0.1 13 4.8 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain cobW PF02492.19 EEB06870.1 - 0.2 11.2 0.6 16 5.0 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.18 EEB06871.1 - 2.5e-09 37.1 8.4 4.2e-09 36.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEB06871.1 - 2e-07 30.3 3.2 4.8e-07 29.1 2.6 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain BATS PF06968.13 EEB06874.1 - 3.6e-19 68.7 0.0 9.9e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EEB06874.1 - 4.5e-16 59.7 0.3 8.5e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF1771 PF08590.10 EEB06875.2 - 2e-10 40.9 6.5 2e-10 40.9 6.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 EEB06875.2 - 4e-06 26.4 0.1 3e-05 23.6 0.0 2.3 1 1 1 2 2 2 1 CUE domain Smr PF01713.21 EEB06875.2 - 4.1e-06 27.0 0.0 9.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Smr domain PAPS_reduct PF01507.19 EEB06876.1 - 5e-34 117.8 0.2 4.7e-33 114.7 0.2 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SNF2_N PF00176.23 EEB06877.1 - 2e-50 171.5 0.1 8.4e-50 169.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB06877.1 - 6.4e-21 74.8 0.5 1.9e-19 70.0 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB06877.1 - 1.6e-12 47.8 0.0 7.9e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEB06877.1 - 1.6e-06 27.6 0.1 5.8e-06 25.7 0.1 2.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase VMA21 PF09446.10 EEB06878.1 - 1.9e-14 53.5 10.0 2.5e-14 53.1 10.0 1.2 1 0 0 1 1 1 1 VMA21-like domain Silic_transp PF03842.13 EEB06878.1 - 0.00073 18.0 0.7 0.00079 17.9 0.7 1.0 1 0 0 1 1 1 1 Silicon transporter FixS PF03597.15 EEB06878.1 - 0.95 9.2 6.0 0.54 10.0 1.1 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GET2 PF08690.10 EEB06879.1 - 1.5e-11 44.6 5.7 1.5e-08 34.7 0.6 2.8 1 1 2 3 3 3 3 GET complex subunit GET2 Sulfate_transp PF00916.20 EEB06880.1 - 1e-70 238.5 15.2 1.3e-70 238.1 15.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEB06880.1 - 1.3e-21 76.4 0.0 4.3e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 EEB06880.1 - 0.0023 18.3 4.8 0.0023 18.3 4.8 3.1 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EEB06880.1 - 0.023 15.0 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 STAS domain Pkinase PF00069.25 EEB06881.2 - 6.1e-33 114.3 0.0 2.1e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06881.2 - 2.5e-20 72.9 0.0 8e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FH2 PF02181.23 EEB06882.2 - 3e-68 230.7 0.8 6.5e-68 229.5 0.8 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EEB06882.2 - 2e-35 122.1 4.3 2e-35 122.1 4.3 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EEB06882.2 - 1.1e-07 31.6 1.0 6.5e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain ABC_tran PF00005.27 EEB06883.1 - 1.3e-19 71.1 0.0 4.5e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EEB06883.1 - 2.2e-12 47.4 0.9 1.9e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB06883.1 - 6.8e-05 22.5 0.3 0.00013 21.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EEB06883.1 - 0.00053 19.6 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EEB06883.1 - 0.0013 18.2 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEB06883.1 - 0.0018 18.8 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EEB06883.1 - 0.0025 17.7 0.2 0.0044 16.9 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase SRP54 PF00448.22 EEB06883.1 - 0.0056 16.3 0.1 0.0089 15.7 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EEB06883.1 - 0.0056 16.4 0.1 0.0077 16.0 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EEB06883.1 - 0.0087 16.1 0.1 0.18 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EEB06883.1 - 0.011 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EEB06883.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EEB06883.1 - 0.047 13.9 0.5 0.17 12.1 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEB06883.1 - 0.055 13.8 0.3 0.1 13.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EEB06883.1 - 0.059 13.8 0.2 0.19 12.1 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EEB06883.1 - 0.062 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EEB06883.1 - 0.1 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_27 PF13514.6 EEB06883.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EEB06883.1 - 0.15 11.0 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EEB06883.1 - 0.23 11.8 0.5 0.47 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EEB06883.1 - 0.24 11.4 0.4 0.41 10.7 0.4 1.3 1 0 0 1 1 1 0 Dynamin family DUF3584 PF12128.8 EEB06883.1 - 0.27 8.7 0.3 0.37 8.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PhoLip_ATPase_C PF16212.5 EEB06884.2 - 3.5e-85 285.7 20.9 3.5e-85 285.7 20.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEB06884.2 - 4.1e-26 90.5 2.7 4.1e-26 90.5 2.7 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEB06884.2 - 1.4e-13 50.7 0.0 6.4e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEB06884.2 - 7.9e-11 42.6 0.4 4e-05 24.0 0.1 3.3 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEB06884.2 - 2e-05 24.2 0.0 4.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEB06884.2 - 0.0033 17.2 0.4 0.0094 15.7 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PBP_N PF17093.5 EEB06884.2 - 0.67 10.2 2.5 1.4 9.2 2.5 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus ketoacyl-synt PF00109.26 EEB06885.1 - 9.2e-52 176.1 1.5 1.2e-51 175.7 1.5 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEB06885.1 - 1.8e-32 111.8 0.2 3.7e-32 110.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EEB06885.1 - 0.0011 18.4 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EEB06885.1 - 0.018 14.9 0.7 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 60KD_IMP PF02096.20 EEB06886.1 - 0.018 14.9 1.2 0.018 14.9 1.2 2.0 2 1 0 2 2 2 0 60Kd inner membrane protein Endonuclease_NS PF01223.23 EEB06887.1 - 7.5e-64 215.6 0.0 9.2e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-Tim10_DDP PF02953.15 EEB06888.1 - 2.4e-25 87.9 0.4 3.1e-25 87.6 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 EEB06888.1 - 0.11 13.0 0.2 0.12 12.8 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) Alg6_Alg8 PF03155.15 EEB06889.1 - 4.8e-166 553.5 29.5 5.8e-166 553.2 29.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Bac_surface_Ag PF01103.23 EEB06890.1 - 9.3e-43 146.9 0.0 1.1e-42 146.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 EEB06890.1 - 0.044 14.3 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat Med27 PF11571.8 EEB06891.1 - 1.5e-07 31.7 2.8 3.5e-07 30.5 2.8 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 HA2 PF04408.23 EEB06892.1 - 5.2e-17 62.1 0.0 1.8e-16 60.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEB06892.1 - 3.4e-11 43.5 0.0 1.5e-10 41.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB06892.1 - 9.3e-08 32.0 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EEB06892.1 - 0.00087 19.6 0.0 0.0029 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MIF4G PF02854.19 EEB06893.1 - 6.4e-59 199.1 0.5 1.5e-58 198.0 0.5 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EEB06893.1 - 7e-13 48.6 0.8 7e-13 48.6 0.8 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Fibrinogen_BP PF08017.11 EEB06893.1 - 2.2e-08 33.0 43.3 2.2e-08 33.0 43.3 1.6 2 0 0 2 2 2 1 Fibrinogen binding protein ACPS PF01648.20 EEB06894.2 - 2.3e-12 47.0 0.0 1.2e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily TPR_1 PF00515.28 EEB06895.1 - 1.9e-33 112.9 33.4 3.3e-07 29.8 0.1 10.8 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06895.1 - 1.5e-32 109.1 30.3 2.5e-06 27.1 0.0 11.1 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06895.1 - 2.5e-26 89.6 25.2 7.9e-06 25.7 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB06895.1 - 7.6e-22 77.3 35.4 4.5e-15 55.6 3.1 6.5 3 1 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EEB06895.1 - 1.2e-14 54.6 7.4 0.00042 20.9 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06895.1 - 4.1e-14 52.8 7.4 0.00087 19.8 0.2 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEB06895.1 - 2.1e-13 49.7 14.4 0.00078 19.1 0.1 8.2 6 2 4 10 10 10 4 TPR repeat TPR_17 PF13431.6 EEB06895.1 - 3.4e-13 49.0 6.6 0.26 11.7 0.0 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06895.1 - 4.2e-13 49.4 19.3 0.0032 17.7 0.1 7.7 6 1 3 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEB06895.1 - 6.5e-13 48.3 7.8 0.18 12.7 0.1 8.7 5 2 5 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EEB06895.1 - 9.3e-10 38.5 0.4 0.0038 17.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB06895.1 - 6.2e-09 35.9 19.5 0.066 13.9 0.1 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06895.1 - 3e-07 30.0 14.7 0.4 10.8 0.0 8.7 9 1 1 10 10 8 2 Tetratricopeptide repeat DUF4810 PF16068.5 EEB06895.1 - 0.0017 18.8 0.3 3.7 8.1 0.0 3.7 4 0 0 4 4 3 1 Domain of unknown function (DUF4810) SNAP PF14938.6 EEB06895.1 - 0.01 15.3 7.2 0.03 13.8 2.8 2.8 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 EEB06895.1 - 0.35 10.8 4.1 48 4.0 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Acyltransferase PF01553.21 EEB06896.1 - 5.8e-28 97.2 0.1 8.3e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase Methyltransf_10 PF05971.12 EEB06897.2 - 1.7e-51 175.3 0.0 2.8e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 EEB06897.2 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EEB06897.2 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain But2 PF09792.9 EEB06898.1 - 6.3e-30 104.4 2.8 6.3e-30 104.4 2.8 2.5 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain TPT PF03151.16 EEB06899.1 - 5.7e-16 58.7 22.2 6.7e-16 58.5 22.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EEB06899.1 - 9e-06 25.9 14.7 9e-06 25.9 14.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family Actin PF00022.19 EEB06901.1 - 9.1e-115 383.5 0.0 4.7e-114 381.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEB06901.1 - 1.6e-06 27.2 0.0 4.3e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein CsgF PF10614.9 EEB06902.1 - 0.76 10.0 3.3 0.61 10.3 0.7 1.8 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Asp PF00026.23 EEB06903.1 - 1.1e-59 202.4 11.2 1.3e-59 202.2 11.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEB06903.1 - 6.6e-12 46.0 3.8 6e-10 39.6 3.8 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEB06903.1 - 0.021 15.5 2.1 2.2 9.0 0.3 3.5 3 1 2 5 5 5 0 Aspartyl protease gag-asp_proteas PF13975.6 EEB06903.1 - 0.026 15.1 0.3 1.3 9.6 0.1 2.8 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease His_Phos_2 PF00328.22 EEB06904.1 - 3.5e-56 191.2 0.0 4.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HhH-GPD PF00730.25 EEB06905.1 - 3.8e-17 62.7 0.0 4.8e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 EEB06905.1 - 0.00011 22.7 0.0 0.71 10.5 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix domain ASL_C PF08328.11 EEB06905.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Glyco_transf_34 PF05637.12 EEB06906.1 - 1.7e-73 247.3 0.1 2.1e-73 247.0 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF5408 PF17402.2 EEB06906.1 - 0.097 12.6 0.5 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5408) CRCB PF02537.15 EEB06907.1 - 1.8e-34 117.9 19.2 2.5e-22 79.0 2.0 2.7 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4239 PF14023.6 EEB06907.1 - 0.44 10.2 2.0 9.4 5.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Phage_holin_3_1 PF05106.12 EEB06907.1 - 2.3 8.7 4.9 30 5.1 0.1 3.2 2 2 2 4 4 4 0 Phage holin family (Lysis protein S) Nuc_deoxyrib_tr PF05014.15 EEB06908.1 - 2.7e-38 131.0 0.1 3.4e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 EEB06908.1 - 4.8e-05 23.6 0.0 9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like GLEYA PF10528.9 EEB06909.1 - 8.1e-21 74.3 1.0 4.7e-20 71.8 1.0 2.5 1 0 0 1 1 1 1 GLEYA domain DUF3221 PF11518.8 EEB06909.1 - 0.73 10.2 9.1 0.46 10.9 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3221) STE2 PF02116.15 EEB06910.1 - 2.6e-68 230.4 31.0 3.2e-68 230.1 31.0 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF5534 PF17686.1 EEB06910.1 - 0.17 12.2 3.2 7.1 6.8 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5534) DUF1771 PF08590.10 EEB06911.2 - 3e-18 65.9 11.6 5.5e-18 65.1 11.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EEB06911.2 - 1.3e-13 51.1 0.2 3.2e-13 49.8 0.2 1.7 1 0 0 1 1 1 1 Smr domain AP_endonuc_2 PF01261.24 EEB06911.2 - 0.045 13.2 0.0 0.066 12.6 0.0 1.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Peptidase_M17_N PF02789.17 EEB06911.2 - 0.05 13.5 0.2 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Vps23_core PF09454.10 EEB06912.1 - 4.3e-11 42.6 0.1 9e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain Dynactin_p22 PF07426.11 EEB06912.1 - 0.021 14.7 0.4 0.04 13.8 0.4 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 DUF3510 PF12022.8 EEB06912.1 - 0.038 14.4 0.2 0.07 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) PTR2 PF00854.21 EEB06914.1 - 8.1e-103 344.3 12.8 1.3e-102 343.6 12.8 1.3 1 0 0 1 1 1 1 POT family ADH_zinc_N PF00107.26 EEB06916.1 - 5.1e-31 107.3 0.1 7.5e-31 106.8 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB06916.1 - 2.4e-16 61.0 0.0 5.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEB06916.1 - 2.2e-14 53.3 0.1 1.7e-13 50.4 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EEB06916.1 - 6.3e-06 25.8 0.0 9.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EEB06916.1 - 0.0076 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EEB06916.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pescadillo_N PF06732.11 EEB06916.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Pescadillo N-terminus Amidase PF01425.21 EEB06917.1 - 5.7e-76 256.3 0.1 4.2e-74 250.1 0.2 2.1 2 0 0 2 2 2 2 Amidase RRM_1 PF00076.22 EEB06918.1 - 9.8e-09 34.9 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YuzL PF14115.6 EEB06918.1 - 0.29 11.6 6.3 0.35 11.4 0.3 3.0 2 1 0 2 2 2 0 YuzL-like protein Lipase_GDSL_2 PF13472.6 EEB06919.1 - 1.5e-14 54.8 0.0 1.8e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEB06919.1 - 9.1e-09 35.6 0.0 2.4e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Zip PF02535.22 EEB06920.1 - 2.1e-38 132.4 12.3 2.4e-38 132.2 12.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Lectin_leg-like PF03388.13 EEB06921.1 - 1.7e-68 230.5 0.0 2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EEB06921.1 - 4.6e-07 30.1 0.0 6.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EEB06921.1 - 0.0033 17.0 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain zf-RING_2 PF13639.6 EEB06922.1 - 1.1e-10 41.7 23.8 8.6e-10 38.8 9.1 2.5 2 0 0 2 2 2 2 Ring finger domain PHD PF00628.29 EEB06922.1 - 4.1e-09 36.2 6.6 4.1e-09 36.2 6.6 2.7 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 EEB06922.1 - 8.8e-08 32.3 4.9 8.8e-08 32.3 4.9 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EEB06922.1 - 4.2e-05 23.2 2.7 4.2e-05 23.2 2.7 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEB06922.1 - 0.00035 20.4 8.6 0.00035 20.4 8.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB06922.1 - 0.00067 19.5 9.4 0.00067 19.5 9.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB06922.1 - 0.0011 18.9 5.9 0.0011 18.9 5.9 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEB06922.1 - 0.0022 17.8 5.7 0.0022 17.8 5.7 2.9 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEB06922.1 - 0.0038 17.2 0.9 0.0038 17.2 0.9 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.6 EEB06922.1 - 0.0066 16.1 0.6 0.023 14.3 0.6 2.0 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 EEB06922.1 - 0.0081 16.2 7.8 0.0081 16.2 7.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 EEB06922.1 - 0.54 10.5 7.9 1.7 8.8 0.9 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEB06922.1 - 3.5 7.9 8.8 2.7 8.3 1.7 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EEB06922.1 - 8.7 6.5 14.5 3.4 7.9 1.7 3.4 2 1 1 3 3 3 0 KIAA1045 RING finger Cofilin_ADF PF00241.20 EEB06923.1 - 1.9e-32 111.6 0.4 5.7e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2113 PF09886.9 EEB06923.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) AA_permease PF00324.21 EEB06924.1 - 1.4e-107 360.3 37.4 1.6e-107 360.1 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB06924.1 - 2.1e-26 92.7 42.0 2.9e-26 92.3 40.8 1.6 1 1 1 2 2 2 2 Amino acid permease Hydantoinase_B PF02538.14 EEB06925.1 - 7.5e-216 717.5 0.2 1e-215 717.0 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EEB06925.1 - 3.5e-100 335.0 0.6 3.5e-100 335.0 0.6 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EEB06925.1 - 1.7e-61 207.1 1.1 6e-60 202.0 0.0 2.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region AAA_lid_7 PF17867.1 EEB06925.1 - 0.12 12.6 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Midasin AAA lid domain CHCH PF06747.13 EEB06926.2 - 4.9e-08 32.9 4.9 9.6e-08 32.0 4.9 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EEB06926.2 - 0.019 14.9 4.9 0.019 14.9 4.9 1.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EEB06926.2 - 0.04 14.2 5.7 0.16 12.3 5.7 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EEB06926.2 - 0.067 13.5 6.2 0.81 10.1 0.5 2.7 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Amidohydro_1 PF01979.20 EEB06927.1 - 1.1e-78 265.0 0.0 1.3e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEB06927.1 - 9.7e-12 45.1 0.0 1.5e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family AA_permease PF00324.21 EEB06928.1 - 4.3e-121 404.8 46.1 5e-121 404.6 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB06928.1 - 5.7e-33 114.4 49.4 7.2e-33 114.0 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease Peroxin-22 PF12827.7 EEB06929.2 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3270 PF11674.8 EEB06929.2 - 0.013 15.6 0.2 0.037 14.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) PBP1_TM PF14812.6 EEB06929.2 - 0.028 14.8 0.2 0.061 13.7 0.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EEB06929.2 - 0.037 13.8 7.6 0.076 12.8 7.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EIIBC-GUT_N PF03612.14 EEB06929.2 - 0.043 13.6 2.1 0.035 13.9 0.9 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Y_phosphatase PF00102.27 EEB06930.1 - 3.5e-62 210.0 0.1 5.2e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EEB06930.1 - 7.2e-11 42.6 0.0 7.5e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 EEB06930.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EEB06930.1 - 5e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EEB06930.1 - 0.0015 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF543 PF04418.12 EEB06931.1 - 6.2e-30 103.0 0.0 7.2e-30 102.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Yippee-Mis18 PF03226.14 EEB06932.1 - 1e-13 51.4 0.4 1.3e-13 51.1 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EEB06932.1 - 0.039 14.2 0.1 0.048 13.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I Sec7 PF01369.20 EEB06933.1 - 3e-30 105.3 2.5 3.5e-30 105.1 1.2 1.7 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 EEB06933.1 - 7.5e-09 36.1 0.7 5.4e-08 33.3 0.2 2.7 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EEB06933.1 - 1.1e-05 25.8 0.0 2.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pox_A_type_inc PF04508.12 EEB06933.1 - 0.95 9.4 3.4 2.7 8.0 0.3 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Pinin_SDK_memA PF04696.13 EEB06934.1 - 8.3e-14 51.8 23.6 8.3e-14 51.8 23.6 2.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region DDE_Tnp_1_3 PF13612.6 EEB06934.1 - 0.56 10.2 2.5 0.82 9.7 2.5 1.3 1 1 0 1 1 1 0 Transposase DDE domain VSG_B PF13206.6 EEB06934.1 - 2.5 7.3 7.6 3.1 6.9 7.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain TFIIA PF03153.13 EEB06934.1 - 7.7 6.4 18.8 9 6.2 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EEB06934.1 - 8.7 5.8 12.8 9.4 5.7 12.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit E1_dh PF00676.20 EEB06935.1 - 9e-116 386.0 0.2 1.4e-115 385.4 0.1 1.3 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EEB06935.1 - 0.0043 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase ADH_zinc_N PF00107.26 EEB06936.1 - 4.6e-14 52.5 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase His_Phos_1 PF00300.22 EEB06937.1 - 1.1e-38 132.9 0.0 1.4e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.21 EEB06938.1 - 2.2e-49 168.3 0.1 8.9e-49 166.3 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.8 EEB06939.2 - 1.8e-15 56.8 19.2 3.8e-15 55.7 7.5 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.6 EEB06939.2 - 7.7e-15 55.1 34.6 9.8e-15 54.8 17.8 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 EEB06939.2 - 1.5e-14 53.9 11.6 2.3e-07 30.2 0.5 3.2 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EEB06939.2 - 3.4e-10 40.2 1.7 1.7e-08 34.6 0.2 2.5 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 EEB06939.2 - 4.4e-09 35.5 8.3 4.4e-09 35.5 8.3 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein family ArAE_1 PF06081.11 EEB06939.2 - 2.5e-05 24.4 10.2 2.5e-05 24.4 10.2 2.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 DUF948 PF06103.11 EEB06939.2 - 0.018 15.3 1.8 0.29 11.4 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PBP1_TM PF14812.6 EEB06939.2 - 0.089 13.2 3.2 0.048 14.0 0.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TBCC_N PF16752.5 EEB06939.2 - 0.45 11.0 3.5 0.59 10.6 0.2 2.8 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain RabGAP-TBC PF00566.18 EEB06940.1 - 8.8e-47 159.5 0.0 2.7e-46 157.9 0.0 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Occludin_ELL PF07303.13 EEB06940.1 - 0.0043 17.8 11.0 0.0072 17.0 9.1 2.5 2 1 0 2 2 2 1 Occludin homology domain SKA2 PF16740.5 EEB06940.1 - 0.047 13.5 9.1 0.078 12.8 6.2 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 EEB06940.1 - 0.06 13.8 12.8 0.047 14.1 5.1 3.2 2 0 0 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 EEB06940.1 - 0.2 11.8 13.4 0.051 13.7 9.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EEB06940.1 - 0.26 10.1 11.4 0.62 8.9 9.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EEB06940.1 - 0.27 10.5 14.1 1.1 8.5 14.0 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 EEB06940.1 - 0.65 10.4 6.0 0.25 11.7 1.4 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family FapA PF03961.13 EEB06940.1 - 6.7 5.2 6.7 11 4.4 6.7 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Y_phosphatase PF00102.27 EEB06941.2 - 1.3e-65 221.3 0.2 1.7e-65 220.9 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EEB06941.2 - 2.2e-05 24.9 0.0 0.001 19.6 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain PTPlike_phytase PF14566.6 EEB06941.2 - 5.8e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EEB06941.2 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EEB06941.2 - 0.002 17.9 0.1 0.0055 16.5 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF383 PF04063.14 EEB06942.2 - 2.6e-70 236.0 0.6 2.8e-67 226.1 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF383) DUF384 PF04064.13 EEB06942.2 - 6.6e-22 77.1 4.1 7.8e-22 76.9 1.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT PF02985.22 EEB06942.2 - 0.011 15.9 0.3 1 9.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EEB06942.2 - 0.071 13.6 0.2 21 5.7 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat tRNA-synt_1 PF00133.22 EEB06943.1 - 1.4e-41 142.5 0.0 8.6e-29 100.2 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEB06943.1 - 9.2e-17 60.9 0.0 2.3e-09 36.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEB06943.1 - 1.4e-14 54.3 0.6 3.3e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEB06943.1 - 2e-09 37.2 0.0 5.1e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pyr_redox_2 PF07992.14 EEB06944.1 - 2.1e-49 168.3 0.4 2.6e-49 168.0 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EEB06944.1 - 1.6e-15 56.8 0.0 4.1e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EEB06944.1 - 1.5e-11 44.7 2.3 1.8e-09 38.0 0.3 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB06944.1 - 2.5e-08 33.5 0.0 1.4e-05 24.5 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EEB06944.1 - 1.1e-06 28.4 0.0 7.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Amino_oxidase PF01593.24 EEB06944.1 - 1.9e-06 27.5 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Reductase_C PF14759.6 EEB06944.1 - 4.8e-06 27.0 0.0 1.3e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.6 EEB06944.1 - 0.00071 19.6 0.0 0.87 9.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EEB06944.1 - 0.0017 17.6 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EEB06944.1 - 0.033 14.6 0.0 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EEB06944.1 - 0.039 13.0 0.8 1.9 7.5 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain EF1G PF00647.19 EEB06945.1 - 4.1e-41 139.4 0.0 7.5e-41 138.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EEB06945.1 - 2.1e-12 47.1 0.1 2.1e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB06945.1 - 1.1e-09 38.2 0.2 3.4e-09 36.6 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEB06945.1 - 3.3e-09 37.0 0.0 8.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEB06945.1 - 7.9e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEB06945.1 - 0.00036 20.7 0.3 0.0016 18.6 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EEB06945.1 - 0.18 11.6 0.3 0.48 10.3 0.3 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 EEB06946.2 - 5.2e-18 64.6 0.0 9.4e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB06946.2 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIR_N PF15912.5 EEB06946.2 - 1.5 8.4 12.9 2.2 7.8 12.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal MS_channel PF00924.18 EEB06947.2 - 3.1e-28 98.7 5.4 1e-27 97.0 5.4 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel Ribosomal_S8e PF01201.22 EEB06948.1 - 1.5e-56 190.3 0.7 1.8e-56 190.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Thioredoxin_7 PF13899.6 EEB06949.1 - 6.9e-20 71.0 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 EEB06949.1 - 5e-14 52.3 0.0 1.2e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EEB06949.1 - 6.1e-14 51.6 0.8 1e-13 50.8 0.2 1.8 2 0 0 2 2 2 1 UBA-like domain Thioredoxin_2 PF13098.6 EEB06949.1 - 1.2e-07 32.2 0.0 3.3e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 EEB06949.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF255 UIM PF02809.20 EEB06949.1 - 0.051 13.5 0.0 0.051 13.5 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Pkinase PF00069.25 EEB06950.1 - 9.5e-68 228.4 0.0 1.3e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06950.1 - 5.5e-45 153.7 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB06950.1 - 0.00011 21.1 0.1 0.00022 20.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEB06950.1 - 0.044 13.1 3.6 0.36 10.1 0.1 3.3 3 1 0 3 3 3 0 Kinase-like ATP-synt_C PF00137.21 EEB06951.1 - 7.7e-24 83.8 27.9 1e-12 48.2 11.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C EMG1 PF03587.14 EEB06952.1 - 8.6e-79 263.7 0.0 1.1e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Utp11 PF03998.13 EEB06953.1 - 3.5e-71 240.0 31.4 3.9e-71 239.9 31.4 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EEB06953.1 - 0.027 13.8 8.8 0.098 12.0 2.4 2.7 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 HEAT_2 PF13646.6 EEB06954.2 - 8.7e-33 112.6 19.7 3.7e-06 27.2 0.1 14.1 11 3 3 14 14 14 8 HEAT repeats HEAT_EZ PF13513.6 EEB06954.2 - 7.6e-30 102.9 27.1 0.013 16.0 0.0 16.8 13 2 6 19 19 19 7 HEAT-like repeat HEAT PF02985.22 EEB06954.2 - 7.1e-29 97.4 29.5 0.0029 17.7 0.0 19.5 19 0 0 19 19 18 7 HEAT repeat Gcn1_N PF12074.8 EEB06954.2 - 1.3e-28 100.4 4.7 1.3e-28 100.4 4.7 5.2 6 1 1 7 7 7 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Cnd1 PF12717.7 EEB06954.2 - 1e-17 64.7 8.1 0.18 11.8 0.0 10.2 6 3 3 10 10 10 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EEB06954.2 - 2.2e-13 50.3 0.4 8.9e-05 22.1 0.0 8.2 7 2 2 9 9 9 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EEB06954.2 - 2.6e-12 47.2 0.0 1.2 9.8 0.0 8.3 6 1 1 7 7 7 3 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 EEB06954.2 - 2.3e-05 24.6 4.0 9.4 6.6 0.1 6.3 5 0 0 5 5 5 2 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.12 EEB06954.2 - 0.0012 18.6 11.8 0.039 13.7 0.3 6.7 7 2 1 8 8 8 2 rRNA processing/ribosome biogenesis Tti2 PF10521.9 EEB06954.2 - 0.0042 16.7 2.6 11 5.5 0.0 5.1 4 1 0 4 4 4 2 Tti2 family Med15_fungi PF05397.12 EEB06954.2 - 0.011 15.9 0.3 0.052 13.8 0.3 2.1 1 0 0 1 1 1 0 Mediator complex subunit 15 IRF PF00605.17 EEB06954.2 - 0.25 11.6 1.1 0.68 10.2 1.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Ric8 PF10165.9 EEB06955.1 - 3.9e-56 191.0 0.0 5.1e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Mitofilin PF09731.9 EEB06956.1 - 1.2e-43 150.0 27.4 1.7e-35 123.0 25.1 2.1 1 1 0 2 2 2 2 Mitochondrial inner membrane protein Spore_III_AF PF09581.10 EEB06956.1 - 1.4 9.0 14.4 0.26 11.3 4.1 2.4 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) MFS_1 PF07690.16 EEB06957.1 - 1.3e-42 146.0 33.5 6e-42 143.8 33.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB06957.1 - 5.7e-15 55.1 19.5 1.7e-12 47.0 3.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EEB06957.1 - 1.4e-12 46.9 9.8 1.4e-12 46.9 9.8 1.6 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HlyIII PF03006.20 EEB06957.1 - 0.0071 16.1 10.2 0.0086 15.8 5.0 3.0 2 1 0 2 2 2 1 Haemolysin-III related Polysacc_synt_4 PF04669.13 EEB06958.1 - 6.9e-22 77.9 0.7 8.9e-20 71.0 0.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis XPG_N PF00752.17 EEB06959.1 - 1e-37 128.7 0.0 3.2e-37 127.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EEB06959.1 - 1.4e-23 83.0 0.6 4.7e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 XPG I-region Sad1_UNC PF07738.13 EEB06960.1 - 8.4e-32 110.0 0.0 1.9e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_M24 PF00557.24 EEB06961.2 - 5.4e-51 173.2 0.0 6.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EEB06961.2 - 6.5e-18 64.8 10.1 1.6e-17 63.5 10.1 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EEB06961.2 - 0.00035 20.6 8.8 0.00035 20.6 8.8 1.9 2 0 0 2 2 2 1 MYND finger PdxJ PF03740.13 EEB06961.2 - 0.12 11.5 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ DnaJ-X PF14308.6 EEB06962.2 - 6.2e-65 218.6 4.1 6.2e-65 218.6 4.1 2.0 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EEB06962.2 - 1.1e-25 89.6 1.9 3.5e-25 87.9 1.9 2.0 1 0 0 1 1 1 1 DnaJ domain CHZ PF09649.10 EEB06963.1 - 9.8e-10 37.7 0.1 9.8e-10 37.7 0.1 1.9 2 0 0 2 2 2 1 Histone chaperone domain CHZ PUF PF00806.19 EEB06964.1 - 1.8e-36 121.8 6.9 9.3e-08 31.4 0.0 8.0 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Phage_int_SAM_4 PF13495.6 EEB06964.1 - 0.078 13.5 0.4 0.62 10.6 0.1 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CFIA_Pcf11 PF11526.8 EEB06965.1 - 5.2e-05 23.7 5.6 0.00017 22.0 0.6 2.5 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EEB06965.1 - 0.00027 21.7 0.0 0.00081 20.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. ADK PF00406.22 EEB06966.1 - 2.2e-62 209.6 0.0 2.7e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEB06966.1 - 4.6e-27 95.1 0.1 7.5e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EEB06966.1 - 2.2e-18 66.0 0.0 4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EEB06966.1 - 1.9e-06 28.4 0.0 4.1e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEB06966.1 - 7.4e-06 26.2 0.0 2.7e-05 24.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EEB06966.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.3 1 1 0 1 1 1 0 Cytidylate kinase RNase_HII PF01351.18 EEB06967.1 - 5.4e-61 205.9 0.0 6.8e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII CAP_GLY PF01302.25 EEB06968.1 - 7.9e-26 89.9 0.4 1.3e-25 89.2 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EEB06968.1 - 5.3e-19 68.5 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EEB06968.1 - 1.3e-07 31.2 0.0 1.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family T6_Ig_like PF18002.1 EEB06968.1 - 0.21 11.5 0.0 0.64 9.9 0.0 1.7 2 0 0 2 2 2 0 T6 antigen Ig like domain BTB PF00651.31 EEB06969.1 - 4.4e-19 68.8 2.1 9.6e-10 38.7 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 EEB06969.1 - 5.1e-08 33.0 0.1 2.2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB06969.1 - 9e-07 29.4 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EEB06969.1 - 4.9e-05 23.6 0.1 0.0002 21.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EEB06969.1 - 0.0012 19.1 0.6 0.13 12.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EEB06969.1 - 0.0013 19.3 0.0 0.0075 16.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 EEB06970.2 - 1.1e-11 45.2 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB06970.2 - 1e-09 39.0 0.0 2.8e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB06970.2 - 3.9e-06 26.8 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB06970.2 - 0.00048 20.8 0.1 0.005 17.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB06970.2 - 0.002 18.0 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Colicin_E5 PF12106.8 EEB06970.2 - 0.03 14.6 0.1 5.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Colicin E5 ribonuclease domain zf-CCHC PF00098.23 EEB06971.2 - 1.1e-40 135.9 51.1 2.2e-07 30.6 0.9 6.6 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.6 EEB06971.2 - 9.9e-14 50.8 36.1 0.0075 16.0 1.1 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 EEB06971.2 - 1.1e-08 34.9 41.0 0.011 15.7 0.3 6.1 1 1 5 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 EEB06971.2 - 0.00021 21.0 0.3 0.00021 21.0 0.3 6.4 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 EEB06971.2 - 0.0046 16.6 34.1 0.17 11.6 1.2 6.2 6 0 0 6 6 6 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EEB06971.2 - 0.0097 15.7 38.6 0.022 14.6 1.1 5.6 5 1 1 6 6 6 4 Zinc knuckle Anti-TRAP PF15777.5 EEB06971.2 - 4.4 7.3 34.7 1.9 8.5 6.5 4.3 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein F-box-like_2 PF13013.6 EEB06972.1 - 2.5e-34 117.5 0.3 2.5e-34 117.5 0.3 2.0 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.7 EEB06972.1 - 0.002 18.0 2.4 0.0057 16.5 2.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EEB06972.1 - 0.11 12.4 0.1 0.44 10.5 0.1 2.1 1 1 0 1 1 1 0 F-box domain EB1 PF03271.17 EEB06973.1 - 1e-15 57.7 2.0 1.2e-15 57.5 0.6 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EEB06973.1 - 5.5e-05 23.3 1.1 7.8e-05 22.8 0.4 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 EEB06973.1 - 0.0042 17.2 0.1 0.0096 16.0 0.1 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein DMAP_binding PF06464.11 EEB06973.1 - 0.041 14.7 0.2 0.3 11.9 0.1 2.2 2 0 0 2 2 2 0 DMAP1-binding Domain Ribosomal_S7e PF01251.18 EEB06974.1 - 1.3e-81 272.8 2.9 1.5e-81 272.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TENA_THI-4 PF03070.16 EEB06975.1 - 1e-09 38.5 0.1 3.4e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family Fungal_trans PF04082.18 EEB06976.1 - 3.6e-26 91.8 0.6 3.6e-26 91.8 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB06976.1 - 6.2e-11 42.2 15.0 1.5e-10 41.1 15.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 EEB06977.1 - 3.2e-17 62.5 0.1 4.6e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EEB06977.1 - 3.5e-10 40.2 0.1 5.9e-10 39.4 0.1 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EEB06977.1 - 3.3e-09 37.0 0.6 1.7e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Mito_carr PF00153.27 EEB06978.1 - 2.9e-66 219.4 4.9 4.2e-23 81.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 EEB06979.1 - 4.4e-19 68.6 2.6 4.4e-19 68.6 2.6 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB06979.1 - 2.2e-08 34.1 11.6 4e-08 33.3 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLM10_mid PF16507.5 EEB06980.2 - 1.5e-146 489.2 4.5 2e-146 488.8 4.5 1.1 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 EEB06980.2 - 2e-05 24.8 0.0 6.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF413 PF04219.12 EEB06980.2 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF MMS19_C PF12460.8 EEB06980.2 - 0.57 9.2 3.6 2.8 7.0 0.7 3.2 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Palm_thioest PF02089.15 EEB06981.1 - 1.5e-66 224.7 0.0 2.6e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PAP2 PF01569.21 EEB06981.1 - 3.8e-10 39.7 5.8 3.8e-10 39.7 5.8 1.6 1 1 0 1 1 1 1 PAP2 superfamily Cyclin_N PF00134.23 EEB06982.1 - 6.2e-18 64.8 1.9 3.4e-10 39.7 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 EEB06982.1 - 0.033 14.2 1.2 0.81 9.8 0.1 2.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Pkinase PF00069.25 EEB06983.1 - 7e-41 140.3 0.1 1.4e-20 73.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB06983.1 - 4.6e-15 55.6 0.1 2.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EEB06983.1 - 0.2 10.6 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.16 EEB06984.1 - 1.1e-42 146.2 32.4 1.1e-42 146.2 32.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily RseC_MucC PF04246.12 EEB06984.1 - 0.85 9.6 5.7 4.4 7.3 0.6 3.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2177 PF09945.9 EEB06984.1 - 2.1 8.4 9.5 0.38 10.8 0.2 3.7 3 1 0 3 3 3 0 Predicted membrane protein (DUF2177) MFS_1 PF07690.16 EEB06985.2 - 4.7e-29 101.4 43.1 4.7e-29 101.4 43.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB06985.2 - 1.2e-10 40.9 8.1 1.2e-10 40.9 8.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Helicase_C PF00271.31 EEB06986.1 - 2e-17 63.5 0.2 1.2e-16 61.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB06986.1 - 8.6e-11 41.9 0.1 3.5e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EEB06986.1 - 1.9e-10 41.0 0.0 6.5e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EEB06986.1 - 1e-05 25.8 0.1 5.3e-05 23.5 0.1 2.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEB06986.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 EEB06986.1 - 0.013 15.4 0.8 0.59 10.0 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 EEB06986.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EEB06986.1 - 0.03 14.8 0.2 0.22 12.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter ATPase PF06745.13 EEB06986.1 - 0.055 12.8 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EEB06986.1 - 0.21 12.0 2.7 0.22 11.9 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EEB06986.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.6 3 1 0 3 3 2 0 AAA domain AA_permease_2 PF13520.6 EEB06987.1 - 2.3e-63 214.5 52.3 2.7e-63 214.3 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB06987.1 - 2.2e-13 49.6 44.0 2.9e-13 49.2 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease AcrZ PF10766.9 EEB06987.1 - 0.18 11.4 2.7 0.24 11.0 0.2 2.5 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ GDI PF00996.18 EEB06988.1 - 2.4e-32 112.0 0.1 2.2e-30 105.6 0.1 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor DUF685 PF05085.12 EEB06988.1 - 0.027 13.8 0.2 0.045 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) ABC1 PF03109.16 EEB06989.2 - 2.9e-37 127.5 0.1 5e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EEB06989.2 - 0.0057 16.3 0.0 0.025 14.2 0.0 2.1 1 0 0 1 1 1 1 RIO1 family TPR_14 PF13428.6 EEB06990.1 - 4.8e-05 23.8 3.1 0.17 12.8 0.3 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEB06990.1 - 0.00026 20.9 7.8 0.00035 20.5 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB06990.1 - 0.00062 19.8 3.8 0.01 16.0 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEB06990.1 - 0.00073 20.0 3.7 0.034 14.7 0.3 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB06990.1 - 0.0016 18.2 0.3 0.0016 18.2 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB06990.1 - 0.016 15.5 1.2 0.59 10.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEB06990.1 - 0.025 14.6 3.3 0.16 12.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEB06990.1 - 0.041 13.6 0.0 3.1 7.6 0.0 3.0 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 EEB06990.1 - 0.056 13.6 0.2 0.38 10.9 0.1 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat PWI PF01480.17 EEB06990.1 - 0.12 12.8 0.0 0.65 10.4 0.0 2.3 1 1 0 1 1 1 0 PWI domain WD40 PF00400.32 EEB06991.1 - 1.7e-15 57.1 1.2 0.0071 17.2 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB06991.1 - 6.3e-05 23.2 0.0 1.6 9.1 0.0 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_binding PF10199.9 EEB06991.1 - 1.7 9.2 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Bot1p PF12298.8 EEB06992.1 - 4.8e-48 163.6 1.2 5.1e-48 163.5 0.3 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Mor PF08765.11 EEB06992.1 - 0.022 14.8 0.1 0.073 13.1 0.0 1.8 2 0 0 2 2 2 0 Mor transcription activator family DUF1910 PF08928.10 EEB06992.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Abhydrolase_1 PF00561.20 EEB06993.2 - 1.9e-25 90.0 0.1 2.9e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EEB06993.2 - 2.7e-21 74.9 0.0 6.2e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EEB06993.2 - 5.5e-08 32.4 0.0 9.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EEB06993.2 - 5.2e-05 23.0 0.0 0.042 13.5 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EEB06993.2 - 9.7e-05 22.3 0.0 0.0093 15.8 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EEB06993.2 - 0.00067 20.3 0.0 0.00085 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EEB06993.2 - 0.0087 15.6 0.0 3.4 7.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Palm_thioest PF02089.15 EEB06993.2 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 EEB06993.2 - 0.016 14.7 0.0 0.24 10.8 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Lipase_2 PF01674.18 EEB06993.2 - 0.1 12.1 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.13 EEB06993.2 - 0.11 12.2 0.1 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.20 EEB06993.2 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 1 0 1 1 1 0 Putative esterase DNA_pol_phi PF04931.13 EEB06994.1 - 3.6e-229 762.8 24.8 3.6e-229 762.8 24.8 1.7 2 0 0 2 2 2 1 DNA polymerase phi SDA1 PF05285.12 EEB06994.1 - 0.1 12.0 17.6 0.22 10.9 17.6 1.5 1 0 0 1 1 1 0 SDA1 Chrome_Resist PF09828.9 EEB06994.1 - 0.26 11.7 4.1 7.4 7.0 0.0 3.4 4 0 0 4 4 4 0 Chromate resistance exported protein SRR1 PF07985.12 EEB06995.1 - 1.1e-12 47.8 0.0 2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 SRR1 UDPG_MGDP_dh_C PF03720.15 EEB06995.1 - 0.084 13.3 0.0 0.73 10.3 0.0 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain RNA_pol_Rpb8 PF03870.15 EEB06996.1 - 1.4e-36 125.7 4.8 4.1e-35 121.0 4.8 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EEB06996.1 - 1.4e-07 31.6 0.1 1.6e-07 31.4 0.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Spa1_C PF18218.1 EEB06996.1 - 0.04 14.3 0.3 0.18 12.2 0.1 1.9 1 1 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain Ribosomal_L28 PF00830.19 EEB06997.2 - 6.3e-14 51.9 0.1 1.1e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family UPF0029 PF01205.19 EEB06998.1 - 3.6e-20 72.2 0.5 9.9e-20 70.8 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 Flavodoxin_5 PF12724.7 EEB06998.1 - 0.066 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain CSTF2_hinge PF14327.6 EEB06998.1 - 0.12 12.8 2.0 2.2 8.8 0.1 2.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Presenilin PF01080.17 EEB06998.1 - 6.4 5.4 11.2 9.2 4.9 11.2 1.2 1 0 0 1 1 1 0 Presenilin SMAP PF15477.6 EEB06999.1 - 6.8e-06 27.0 0.8 6.8e-06 27.0 0.8 2.9 2 2 0 2 2 2 1 Small acidic protein family CSRNP_N PF16019.5 EEB06999.1 - 0.053 13.4 7.9 0.068 13.1 7.9 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus AAA_22 PF13401.6 EEB07000.2 - 1.8e-14 54.2 0.1 7.3e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEB07000.2 - 1.8e-13 51.0 0.0 8.5e-13 48.9 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEB07000.2 - 9.3e-11 42.4 0.0 4.7e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 EEB07000.2 - 3e-10 39.9 0.1 8.4e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 EEB07000.2 - 3.5e-07 30.3 0.1 1.2e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EEB07000.2 - 9.3e-07 29.3 0.1 8.4e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EEB07000.2 - 0.00048 19.5 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EEB07000.2 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 EEB07000.2 - 0.00078 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 EEB07000.2 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 EEB07000.2 - 0.0029 17.0 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein PIF1 PF05970.14 EEB07000.2 - 0.0036 16.5 0.0 0.0057 15.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EEB07000.2 - 0.0038 17.0 0.0 0.0093 15.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EEB07000.2 - 0.0041 16.7 0.1 0.0078 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 EEB07000.2 - 0.0068 16.2 0.2 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EEB07000.2 - 0.0074 15.8 0.4 0.019 14.5 0.5 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EEB07000.2 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 EEB07000.2 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Helicase Viral_helicase1 PF01443.18 EEB07000.2 - 0.013 15.3 2.4 0.21 11.3 0.1 3.2 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EEB07000.2 - 0.015 15.0 0.1 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 EEB07000.2 - 0.023 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 EEB07000.2 - 0.043 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EEB07000.2 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 EEB07000.2 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_32 PF13654.6 EEB07000.2 - 0.17 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EEB07001.1 - 6.4e-14 52.1 12.5 0.00013 22.7 0.1 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07001.1 - 1.3e-11 44.6 0.1 2.8e-05 24.3 0.0 3.8 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EEB07001.1 - 0.015 14.0 2.6 0.79 8.4 0.8 3.4 1 1 2 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EEB07001.1 - 0.056 13.3 0.4 1.9 8.4 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Glyco_hydro_15 PF00723.21 EEB07002.2 - 2.6e-67 227.5 0.0 3.3e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Tim44 PF04280.15 EEB07003.1 - 4.1e-35 121.0 0.2 6.2e-35 120.5 0.2 1.3 1 0 0 1 1 1 1 Tim44-like domain CwfJ_C_1 PF04677.15 EEB07004.2 - 3.4e-38 130.2 1.1 1.1e-37 128.6 0.3 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EEB07004.2 - 3.3e-22 79.2 0.2 1.2e-21 77.5 0.2 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rad52_Rad22 PF04098.15 EEB07005.2 - 8.8e-58 194.6 0.0 1.3e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HlyIII PF03006.20 EEB07006.1 - 4.8e-56 190.0 23.7 6e-56 189.7 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ribosomal_L38e PF01781.18 EEB07007.1 - 7.7e-35 118.8 1.8 8.7e-35 118.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family UQ_con PF00179.26 EEB07008.1 - 2.6e-48 163.2 0.0 3e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEB07008.1 - 0.00058 19.6 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEB07008.1 - 0.11 12.8 1.2 0.19 12.0 1.2 1.6 1 1 0 1 1 1 0 RWD domain KH_1 PF00013.29 EEB07009.2 - 5.1e-06 26.2 0.1 0.0002 21.1 0.0 2.6 2 1 0 2 2 2 1 KH domain Mvb12 PF09452.10 EEB07009.2 - 0.16 12.4 0.1 0.54 10.7 0.0 1.8 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 ThiF PF00899.21 EEB07010.1 - 3.6e-44 151.0 0.0 5.3e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EEB07010.1 - 1.7e-05 25.0 1.6 0.00021 21.5 1.6 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EEB07010.1 - 0.086 12.4 0.3 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EEB07010.1 - 0.15 12.5 0.3 3.9 8.0 0.0 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.18 EEB07010.1 - 0.19 12.0 0.4 0.82 9.9 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain ApbA PF02558.16 EEB07010.1 - 0.19 11.4 0.3 0.46 10.1 0.2 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA TRAM_LAG1_CLN8 PF03798.16 EEB07011.1 - 1.8e-36 125.8 29.5 1.8e-36 125.8 29.5 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EEB07011.1 - 4.1e-17 61.6 0.7 4.1e-17 61.6 0.7 2.2 2 0 0 2 2 2 1 TRAM1-like protein Herpes_TK PF00693.18 EEB07012.2 - 0.0042 16.3 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 Thymidine kinase from herpesvirus DUF3336 PF11815.8 EEB07015.1 - 1.5e-34 118.6 4.9 2.8e-34 117.8 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEB07015.1 - 1.4e-19 71.1 0.0 3.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.17 EEB07015.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_M9 PF01752.17 EEB07015.1 - 0.062 12.5 0.2 0.092 12.0 0.2 1.2 1 0 0 1 1 1 0 Collagenase Abhydrolase_6 PF12697.7 EEB07015.1 - 0.091 13.4 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PLA2_B PF01735.18 EEB07016.1 - 1.5e-175 584.4 1.6 1.8e-175 584.1 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 EEB07017.1 - 2.4e-203 676.0 7.4 2.8e-203 675.8 7.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EEB07017.1 - 0.069 13.4 2.9 0.15 12.3 2.9 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain HemeBinding_Shp PF11545.8 EEB07017.1 - 0.079 12.9 0.2 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Cell surface heme-binding protein Shp Cytochrom_D1 PF02239.16 EEB07018.1 - 0.00015 20.5 1.7 0.002 16.8 0.3 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 EEB07018.1 - 0.0005 19.5 0.2 0.0014 18.0 0.1 1.7 3 0 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 EEB07018.1 - 0.0016 18.9 5.2 0.22 12.0 0.2 4.3 4 0 0 4 4 4 1 PQQ-like domain CDC45 PF02724.14 EEB07018.1 - 0.067 11.5 5.0 0.098 10.9 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ANAPC4_WD40 PF12894.7 EEB07018.1 - 0.16 12.3 1.9 4.9 7.5 0.6 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DTHCT PF08070.11 EEB07018.1 - 1 10.1 14.2 7.5 7.4 12.8 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region zf-C2HC5 PF06221.13 EEB07019.1 - 2e-22 78.9 6.0 3.2e-22 78.3 6.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type RD3 PF14473.6 EEB07019.1 - 0.12 12.2 6.9 0.24 11.2 0.9 2.8 2 0 0 2 2 2 0 RD3 protein YebO PF13974.6 EEB07019.1 - 5.1 7.3 13.2 0.14 12.3 0.5 3.2 3 0 0 3 3 3 0 YebO-like protein CTD PF12815.7 EEB07020.1 - 2.6e-38 130.4 60.7 4.3e-19 68.8 25.6 3.7 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 EEB07020.1 - 3.3e-28 97.4 0.0 6.4e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 EEB07020.1 - 1.5e-20 72.4 12.0 4e-09 36.1 1.5 5.7 5 0 0 5 5 5 3 KOW motif Spt5_N PF11942.8 EEB07020.1 - 2.2e-18 67.1 11.8 2.2e-18 67.1 11.8 3.2 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 EEB07020.1 - 0.025 14.8 0.1 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) MS_channel PF00924.18 EEB07020.1 - 0.18 11.3 0.5 0.61 9.6 0.0 2.1 2 1 1 3 3 3 0 Mechanosensitive ion channel PTCB-BRCT PF12738.7 EEB07021.1 - 1.5e-39 133.8 0.0 2.4e-19 69.0 0.0 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EEB07021.1 - 8.5e-38 128.6 1.2 1.7e-12 47.5 0.0 4.6 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEB07021.1 - 3.1e-13 49.9 0.0 2.2e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEB07021.1 - 4e-08 33.4 0.3 0.0003 21.0 0.0 4.6 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EEB07021.1 - 0.0022 17.9 0.0 9.8 6.1 0.0 3.4 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Methyltr_RsmB-F PF01189.17 EEB07022.2 - 3.6e-36 124.7 0.0 1.2e-32 113.2 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EEB07022.2 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Lipase_3 PF01764.25 EEB07023.1 - 3.1e-07 30.3 0.0 6.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EEB07023.1 - 0.22 10.7 0.4 0.42 9.9 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RNA_pol_Rpb5_C PF01191.19 EEB07024.1 - 2.9e-33 113.5 0.5 7.2e-33 112.3 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EEB07024.1 - 1e-25 90.1 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EEB07024.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 Restriction endonuclease ALG11_N PF15924.5 EEB07024.1 - 0.04 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus Sof1 PF04158.14 EEB07024.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Sof1-like domain Glyco_trans_1_4 PF13692.6 EEB07025.1 - 5.6e-10 39.8 0.0 1.8e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EEB07025.1 - 3.3e-09 36.5 0.0 8.2e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EEB07025.1 - 8.1e-06 26.2 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEB07025.1 - 0.003 18.0 0.0 0.0054 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EEB07025.1 - 0.029 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Use1 PF09753.9 EEB07026.1 - 0.0012 18.6 0.6 0.0015 18.3 0.6 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1664 PF07889.12 EEB07026.1 - 0.011 15.8 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 EEB07026.1 - 0.012 15.5 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Sec20 Syntaxin_2 PF14523.6 EEB07026.1 - 0.044 14.1 0.6 0.058 13.8 0.6 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Pkinase PF00069.25 EEB07027.1 - 3.6e-27 95.4 0.0 4.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07027.1 - 9.9e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB07027.1 - 1e-09 37.7 0.2 1.4e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB07027.1 - 9.6e-05 22.4 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEB07027.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 EEB07027.1 - 0.089 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EEB07027.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like ATP-synt_J PF04911.12 EEB07028.1 - 3.7e-21 74.5 0.0 4.6e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain Transport_MerF PF11431.8 EEB07028.1 - 0.037 13.9 0.9 0.055 13.4 0.9 1.3 1 0 0 1 1 1 0 Membrane transport protein MerF DJ-1_PfpI PF01965.24 EEB07029.1 - 1.4e-31 109.5 0.0 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EEB07029.1 - 0.0031 17.2 0.0 0.0074 16.0 0.0 1.6 1 1 0 2 2 2 1 ThiJ/PfpI family-like SNO PF01174.19 EEB07029.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Enolase_C PF00113.22 EEB07030.1 - 1.3e-147 490.8 0.0 1.7e-147 490.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EEB07030.1 - 2e-58 196.2 0.3 3.8e-58 195.3 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EEB07030.1 - 2.5e-09 37.0 0.0 5.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EEB07030.1 - 0.0075 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus gerPA PF10676.9 EEB07031.1 - 0.046 14.0 7.6 5 7.4 2.1 3.0 3 0 0 3 3 3 0 Spore germination protein gerPA/gerPF AA_permease_2 PF13520.6 EEB07034.2 - 7.2e-57 193.1 55.0 8.8e-57 192.8 55.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07034.2 - 5.9e-19 68.0 44.5 8.1e-19 67.6 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.13 EEB07035.1 - 1.6e-23 83.4 0.3 2.7e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 RTA1 like protein Imm6 PF14434.6 EEB07035.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.8 1 1 0 1 1 1 0 Immunity protein Imm6 PglL_A PF15864.5 EEB07035.1 - 7.6 6.4 5.8 2.1 8.1 0.7 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase CUE PF02845.16 EEB07036.1 - 3.3e-10 39.5 0.1 5.6e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 CUE domain TFR_dimer PF04253.15 EEB07037.1 - 1.7e-23 83.0 0.0 2.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EEB07037.1 - 8.3e-10 38.7 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EEB07037.1 - 3.4e-08 33.4 0.0 8.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 PA domain ThrE PF06738.12 EEB07038.1 - 1.1e-59 201.8 13.0 3.7e-57 193.5 0.6 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EEB07038.1 - 1.6e-11 44.4 7.0 1.6e-11 44.4 7.0 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE AzlD PF05437.12 EEB07038.1 - 0.059 13.5 2.3 0.17 12.1 2.3 1.8 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DNMT1-RFD PF12047.8 EEB07039.1 - 2.7e-18 66.4 0.7 7.4e-18 65.0 0.3 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain SURF4 PF02077.15 EEB07040.1 - 2.3e-104 348.7 7.1 2.6e-104 348.5 7.1 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 EEB07040.1 - 0.069 13.3 0.3 0.069 13.3 0.3 2.9 3 1 0 3 3 3 0 HR-like lesion-inducing TMPIT PF07851.13 EEB07040.1 - 0.076 12.3 0.4 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 TMPIT-like protein Holin_SPP1 PF04688.13 EEB07040.1 - 3.2 8.0 7.0 0.19 12.0 0.9 2.1 2 1 1 3 3 3 0 SPP1 phage holin Ribosomal_L36e PF01158.18 EEB07041.1 - 1.2e-39 134.5 2.5 1.3e-39 134.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 EEB07041.1 - 0.0063 16.6 0.1 0.0073 16.4 0.1 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain PBS_linker_poly PF00427.21 EEB07041.1 - 0.037 14.1 0.2 0.044 13.8 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide cobW PF02492.19 EEB07044.2 - 4.7e-48 163.1 3.9 4.7e-48 163.1 3.9 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEB07044.2 - 6.2e-19 67.7 0.1 3.6e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain T2SSE PF00437.20 EEB07044.2 - 0.00083 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EEB07044.2 - 0.026 14.4 0.1 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase RecA PF00154.21 EEB07044.2 - 0.028 13.9 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Viral_helicase1 PF01443.18 EEB07044.2 - 0.038 13.7 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EEB07044.2 - 0.039 14.0 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EEB07044.2 - 0.04 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EEB07044.2 - 0.043 14.2 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EEB07044.2 - 0.046 13.6 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain CDC45 PF02724.14 EEB07044.2 - 0.069 11.4 0.2 0.096 11.0 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_33 PF13671.6 EEB07044.2 - 0.082 13.1 0.1 0.43 10.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EEB07044.2 - 0.12 12.9 0.4 4.5 7.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DUF2457 PF10446.9 EEB07044.2 - 3.6 6.6 9.2 5.4 6.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SSF PF00474.17 EEB07045.1 - 1.7e-17 63.4 24.7 3.5e-17 62.4 24.7 1.6 1 0 0 1 1 1 1 Sodium:solute symporter family MRAP PF15183.6 EEB07045.1 - 1.2 9.1 8.8 1.5 8.8 0.1 3.7 4 0 0 4 4 4 0 Melanocortin-2 receptor accessory protein family Transferase PF02458.15 EEB07046.1 - 5.7e-23 81.3 0.0 8.1e-22 77.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family Transferase PF02458.15 EEB07047.2 - 1.2e-19 70.3 0.0 1.2e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Transferase family Glyco_hydro_31 PF01055.26 EEB07051.2 - 3.6e-143 477.9 9.2 6.7e-143 477.0 9.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EEB07051.2 - 3.4e-31 107.8 0.1 8.3e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EEB07051.2 - 1.2e-05 25.5 0.3 5.8e-05 23.3 0.3 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like Exonuc_VII_S PF02609.16 EEB07051.2 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Exonuclease VII small subunit RTA1 PF04479.13 EEB07052.2 - 4.9e-55 186.4 5.0 7.3e-55 185.8 5.0 1.3 1 0 0 1 1 1 1 RTA1 like protein SLBB PF10531.9 EEB07052.2 - 0.012 15.4 0.5 1.8 8.5 0.1 3.1 3 0 0 3 3 3 0 SLBB domain DUF202 PF02656.15 EEB07052.2 - 1 9.8 6.3 19 5.8 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) AA_permease_2 PF13520.6 EEB07053.1 - 2.6e-51 174.8 50.8 3.2e-51 174.5 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07053.1 - 2.1e-16 59.6 41.2 3.1e-16 59.0 41.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5336 PF17270.2 EEB07053.1 - 9.7 5.8 16.2 3.3 7.3 0.1 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5336) Gp_dh_C PF02800.20 EEB07055.1 - 9.1e-72 239.8 0.1 1.3e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEB07055.1 - 4e-40 136.2 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEB07055.1 - 0.028 14.5 1.6 0.1 12.7 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EEB07055.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3576 PF12100.8 EEB07055.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) Zn_clus PF00172.18 EEB07058.1 - 4.8e-05 23.4 14.8 8.7e-05 22.6 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei5_like PF17021.5 EEB07058.1 - 0.022 14.8 1.7 0.038 14.0 0.3 2.0 2 0 0 2 2 2 0 Putative double-strand recombination repair-like MFS_1 PF07690.16 EEB07059.1 - 2.1e-39 135.5 33.7 2.2e-37 128.8 34.9 2.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 EEB07059.1 - 2.7e-07 30.2 5.8 2.7e-07 30.2 5.8 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OSTbeta PF15048.6 EEB07059.1 - 0.098 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SLAC1 PF03595.17 EEB07060.1 - 2.7e-63 214.2 43.6 3.1e-63 214.0 43.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phage_holin_5_2 PF16079.5 EEB07060.1 - 9.4 6.7 11.3 41 4.6 0.6 3.4 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V FMN_dh PF01070.18 EEB07061.1 - 1.9e-117 392.2 0.0 2.2e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EEB07061.1 - 2e-05 24.0 0.0 0.068 12.5 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EEB07061.1 - 0.00018 20.6 1.0 0.0022 17.0 0.5 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EEB07061.1 - 0.00025 20.6 0.3 0.00037 20.0 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EEB07061.1 - 0.0038 16.4 0.1 0.0057 15.8 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EEB07061.1 - 0.011 15.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Histidine biosynthesis protein Acetyltransf_CG PF14542.6 EEB07062.2 - 0.19 11.8 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AA_permease_2 PF13520.6 EEB07063.1 - 5.4e-36 124.3 39.3 7e-36 124.0 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07063.1 - 6e-18 64.7 35.8 8.6e-18 64.2 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease GFA PF04828.14 EEB07064.1 - 3.4e-08 33.7 1.2 4.6e-08 33.3 0.1 1.8 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.25 EEB07065.1 - 2e-45 154.7 0.1 2.9e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB07065.1 - 6.8e-30 104.3 0.0 9.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB07065.1 - 4.4e-10 39.8 0.0 7.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEB07065.1 - 4.8e-07 29.8 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEB07065.1 - 2.5e-06 27.1 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EEB07065.1 - 8.9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain EFhand_Ca_insen PF08726.10 EEB07065.1 - 0.02 15.0 0.2 0.068 13.3 0.1 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand NAD_binding_4 PF07993.12 EEB07066.1 - 2e-38 132.1 0.0 3e-37 128.2 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EEB07066.1 - 4e-18 65.2 0.0 1.7e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EEB07066.1 - 4.8e-14 52.4 0.0 8.2e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EEB07066.1 - 9.3e-07 28.5 0.0 2.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EEB07066.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EEB07066.1 - 1.1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EEB07066.1 - 5.8e-05 22.2 0.0 0.00015 20.8 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EEB07066.1 - 0.00041 20.3 0.0 0.00092 19.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EEB07066.1 - 0.00076 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EEB07066.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EEB07066.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Transp_cyt_pur PF02133.15 EEB07067.2 - 4.2e-149 497.1 44.0 5e-149 496.8 44.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin G6PD_C PF02781.16 EEB07068.1 - 1.9e-85 286.6 0.0 2.4e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EEB07068.1 - 2.3e-42 145.6 0.0 3.9e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_S10 PF00338.22 EEB07068.1 - 0.024 14.9 0.0 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e Fungal_trans PF04082.18 EEB07069.2 - 4.5e-29 101.3 1.7 6.6e-29 100.8 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB07069.2 - 4.2e-09 36.4 11.1 7.9e-09 35.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 EEB07070.1 - 5.9e-135 450.5 40.3 7.1e-135 450.3 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB07070.1 - 2.2e-33 115.7 43.8 2.7e-33 115.4 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 EEB07071.1 - 1.2e-21 77.1 0.0 2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEB07071.1 - 1.6e-17 63.3 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEB07071.1 - 1.5e-06 29.3 0.0 3.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 EEB07072.1 - 1.9e-29 102.7 35.2 1.9e-29 102.7 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07072.1 - 2e-10 40.2 15.7 2e-10 40.2 15.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 EEB07072.1 - 0.0057 16.7 3.7 0.0057 16.7 3.7 4.2 3 2 1 4 4 4 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3185 PF11381.8 EEB07072.1 - 0.011 15.7 2.5 0.037 14.0 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF21 PF01595.20 EEB07072.1 - 6.4 6.5 11.3 1.4 8.6 3.0 2.7 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SSI PF00720.17 EEB07073.1 - 0.00025 21.0 0.5 0.00041 20.3 0.5 1.3 1 0 0 1 1 1 1 Subtilisin inhibitor-like DUF3372 PF11852.8 EEB07073.1 - 0.049 13.1 0.3 0.068 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Stress-antifung PF01657.17 EEB07073.1 - 1.5 9.5 7.6 0.1 13.3 1.7 2.0 2 1 0 2 2 2 0 Salt stress response/antifungal GFO_IDH_MocA PF01408.22 EEB07074.1 - 8.2e-23 81.5 0.1 1.2e-22 81.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEB07074.1 - 2.9e-11 43.4 0.0 4.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EEB07074.1 - 3.6e-05 24.4 0.1 5.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain G6PD_N PF00479.22 EEB07074.1 - 0.046 14.3 0.1 0.07 13.8 0.1 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EEB07074.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EEB07074.1 - 0.13 13.0 0.2 0.35 11.6 0.2 1.6 1 0 0 1 1 1 0 CoA binding domain MFS_1 PF07690.16 EEB07075.1 - 2e-32 112.5 28.0 2e-32 112.5 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07075.1 - 8.3e-09 34.8 13.9 8.3e-09 34.8 13.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Ribonucleas_3_3 PF14622.6 EEB07076.1 - 7.4e-23 81.1 0.0 1.2e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEB07076.1 - 9e-20 71.3 0.1 7e-19 68.4 0.1 2.4 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 EEB07076.1 - 1.2e-08 35.5 0.2 2.3e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif FAF PF11250.8 EEB07076.1 - 0.021 15.1 0.3 1 9.6 0.1 2.6 3 0 0 3 3 3 0 Fantastic Four meristem regulator HhH-GPD PF00730.25 EEB07077.1 - 8e-13 48.8 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2330 PF10092.9 EEB07077.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) HHH_5 PF14520.6 EEB07077.1 - 0.069 13.8 0.0 23 5.7 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain SAM_1 PF00536.30 EEB07077.1 - 0.082 13.4 0.1 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TAP35_44 PF07265.11 EEB07077.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 2-oxoacid_dh PF00198.23 EEB07078.1 - 7e-79 264.5 0.2 8.9e-79 264.2 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEB07078.1 - 1.4e-16 60.0 0.1 2.7e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EEB07078.1 - 5.5e-16 58.6 0.1 1.7e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Peptidase_C11 PF03415.14 EEB07079.1 - 0.025 14.0 0.7 0.029 13.8 0.7 1.1 1 0 0 1 1 1 0 Clostripain family CUTL PF16557.5 EEB07079.1 - 0.1 12.8 1.0 2.2 8.5 0.0 2.8 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB Sec7 PF01369.20 EEB07080.1 - 1.7e-70 236.5 2.1 1.7e-70 236.5 2.1 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EEB07080.1 - 7.6e-43 146.1 3.7 7.6e-43 146.1 3.7 4.4 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EEB07080.1 - 1.9e-29 101.3 18.0 5.3e-29 99.9 0.4 5.6 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 EEB07080.1 - 1.2e-17 64.1 6.4 1.2e-17 64.1 6.4 3.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 PWI PF01480.17 EEB07080.1 - 0.078 13.3 0.7 0.72 10.2 0.0 2.9 3 0 0 3 3 3 0 PWI domain GDPD PF03009.17 EEB07081.1 - 4.7e-28 98.6 0.0 7.3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.32 EEB07082.1 - 1.6e-37 126.8 21.6 6.1e-08 33.2 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07082.1 - 6.1e-07 29.6 0.6 6.4 7.1 0.0 6.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EEB07082.1 - 8.4e-06 25.6 0.6 2.1e-05 24.3 0.6 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EEB07082.1 - 1.2e-05 24.2 6.2 0.14 10.7 0.1 4.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EEB07082.1 - 2.1e-05 24.0 0.6 7.5e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 WD40-like domain F-box PF00646.33 EEB07082.1 - 2.7e-05 23.9 0.8 6.9e-05 22.6 0.8 1.7 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 EEB07082.1 - 0.12 11.3 1.7 58 2.4 0.0 4.1 3 2 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Prenyltransf PF01255.19 EEB07083.1 - 2.2e-74 249.7 0.0 2.8e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1707 PF08044.11 EEB07083.1 - 0.081 13.0 0.8 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) WD40 PF00400.32 EEB07084.1 - 2.3e-23 82.0 0.6 2.2e-05 25.1 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07084.1 - 1.5e-12 47.6 0.0 0.14 12.5 0.0 5.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB07084.1 - 0.00012 20.8 0.3 0.028 13.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EEB07084.1 - 0.016 14.6 0.0 0.073 12.4 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 EEB07084.1 - 0.033 13.2 0.9 1 8.2 0.1 2.7 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EEB07084.1 - 0.074 11.6 0.0 0.38 9.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain MOZ_SAS PF01853.18 EEB07085.1 - 2e-79 265.4 0.6 3.2e-79 264.8 0.6 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEB07085.1 - 5.7e-19 67.5 7.1 5.7e-19 67.5 7.1 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EEB07085.1 - 0.0046 17.3 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_24 PF13412.6 EEB07085.1 - 0.019 14.5 0.3 0.97 9.0 0.1 2.6 2 1 1 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EEB07085.1 - 0.026 14.3 0.0 0.41 10.5 0.0 2.3 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain TFIIE_beta PF02186.15 EEB07085.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 TFIIE beta subunit core domain HTH_9 PF08221.11 EEB07085.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ALMT PF11744.8 EEB07085.1 - 0.12 11.1 0.3 0.18 10.6 0.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec3_C_2 PF15278.6 EEB07086.1 - 4.4e-47 158.3 3.1 9.4e-47 157.3 3.1 1.6 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Sec3-PIP2_bind PF15277.6 EEB07086.1 - 2.9e-11 43.4 0.1 5e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EEB07086.1 - 0.00022 19.8 3.1 0.00032 19.2 3.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 PH PF00169.29 EEB07086.1 - 0.048 14.2 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 PH domain RNA_pol_Rpb1_4 PF05000.17 EEB07086.1 - 0.095 12.7 0.5 0.24 11.4 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Corona_S2 PF01601.16 EEB07086.1 - 0.34 9.3 1.3 0.49 8.8 1.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Gly_transf_sug PF04488.15 EEB07087.1 - 7.7e-23 81.0 0.3 2e-22 79.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EEB07087.1 - 8e-05 22.1 0.9 0.065 12.5 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EEB07087.1 - 0.00051 19.5 0.5 0.00079 18.9 0.5 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein FHA PF00498.26 EEB07088.1 - 1.1e-16 60.9 0.2 4.4e-16 59.0 0.1 2.1 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 EEB07088.1 - 1e-10 41.2 8.5 1e-10 41.2 8.5 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 EEB07088.1 - 4.6e-05 23.7 16.0 7.3e-05 23.0 14.8 2.0 2 0 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 EEB07088.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 EEB07088.1 - 0.082 13.0 7.1 0.17 12.0 7.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EEB07088.1 - 0.11 12.4 12.4 3.5 7.5 14.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB07088.1 - 0.14 12.2 13.1 0.27 11.2 13.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EEB07088.1 - 0.34 11.2 12.9 12 6.3 12.4 3.0 2 1 1 3 3 3 0 RING-H2 zinc finger domain PHD PF00628.29 EEB07088.1 - 2.6 8.0 12.0 4.4 7.3 10.7 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 EEB07088.1 - 6.3 6.9 13.3 30 4.8 13.3 2.2 2 0 0 2 2 2 0 RING-type zinc-finger COMPASS-Shg1 PF05205.12 EEB07089.1 - 4.2e-24 85.2 3.4 5e-24 85.0 3.4 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Sec23_helical PF04815.15 EEB07089.1 - 0.024 14.4 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain IcmF_C PF06744.12 EEB07089.1 - 0.042 13.4 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal hnRNP_Q_AcD PF18360.1 EEB07089.1 - 0.084 12.8 0.9 5.2 7.1 0.2 2.7 2 1 1 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF2175 PF09943.9 EEB07089.1 - 0.14 12.5 1.7 0.26 11.6 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GTP_EFTU PF00009.27 EEB07090.1 - 3.9e-56 189.7 0.1 1e-55 188.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EEB07090.1 - 1.6e-14 53.7 0.0 5.4e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB07090.1 - 1.6e-12 47.6 0.2 9.2e-12 45.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEB07090.1 - 1.6e-08 34.5 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EEB07090.1 - 2.2e-05 24.2 0.0 0.00011 22.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EEB07090.1 - 0.0028 17.7 0.1 0.0071 16.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DNA_pol_E_B PF04042.16 EEB07091.1 - 1.1e-38 132.7 1.2 1.7e-38 132.1 1.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EEB07091.1 - 1.1e-33 117.2 4.6 4.6e-20 72.6 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal GPI-anchored PF10342.9 EEB07092.1 - 5.2e-13 49.6 7.6 5.2e-13 49.6 7.6 3.5 2 1 1 3 3 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TcfC PF16967.5 EEB07092.1 - 0.039 13.4 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 E-set like domain Utp14 PF04615.13 EEB07092.1 - 0.65 8.5 17.2 0.78 8.2 17.2 1.1 1 0 0 1 1 1 0 Utp14 protein SAPS PF04499.15 EEB07092.1 - 1.9 7.2 9.2 2.1 7.0 9.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.11 EEB07092.1 - 2.6 6.4 24.9 2.8 6.3 24.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.13 EEB07092.1 - 3.1 7.3 15.9 3.8 7.1 15.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.12 EEB07092.1 - 3.4 5.8 11.7 4.1 5.5 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.19 EEB07092.1 - 4 7.3 32.5 5.3 6.9 32.5 1.3 1 0 0 1 1 1 0 SPX domain SLC12 PF03522.15 EEB07092.1 - 7.1 5.5 9.7 9.1 5.2 9.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 EEB07092.1 - 8.5 5.0 15.2 11 4.6 15.2 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 EEB07092.1 - 9.8 4.8 19.3 16 4.2 19.3 1.4 1 0 0 1 1 1 0 Presenilin TFIIA_gamma_N PF02268.16 EEB07093.2 - 2e-25 88.5 0.1 2.8e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EEB07093.2 - 4.9e-23 81.0 0.6 8.6e-23 80.2 0.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Malic_M PF03949.15 EEB07095.1 - 6.5e-92 307.4 0.0 8.4e-92 307.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EEB07095.1 - 8.2e-60 201.7 0.0 1.6e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ENTH PF01417.20 EEB07096.1 - 3.9e-47 159.4 0.9 8.3e-47 158.3 0.9 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EEB07096.1 - 8.6e-05 21.7 0.3 0.00015 20.9 0.3 1.4 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EEB07096.1 - 0.01 15.7 0.2 0.019 14.8 0.2 1.4 1 0 0 1 1 1 1 VHS domain UDPGP PF01704.18 EEB07097.1 - 1.6e-171 570.6 0.0 1.8e-171 570.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Q_salvage PF10343.9 EEB07098.1 - 5e-18 65.7 0.0 9.6e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family PFL-like PF02901.15 EEB07098.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like GTP_EFTU PF00009.27 EEB07099.1 - 2.5e-54 183.8 0.5 3.9e-54 183.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEB07099.1 - 2.6e-41 140.4 0.0 5.4e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEB07099.1 - 3.7e-14 52.9 1.5 3.7e-14 52.9 1.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB07099.1 - 0.00042 20.4 0.2 0.011 15.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EEB07099.1 - 0.025 14.4 0.8 0.083 12.8 0.8 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Rep_fac_C PF08542.11 EEB07101.1 - 8.9e-20 70.9 0.6 3.3e-19 69.1 0.2 2.2 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EEB07101.1 - 1.8e-17 64.0 0.0 4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEB07101.1 - 1.7e-16 60.5 0.3 8.6e-12 45.1 0.2 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EEB07101.1 - 3.6e-09 36.8 0.0 2.1e-08 34.3 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EEB07101.1 - 6e-06 26.7 0.0 2.6e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EEB07101.1 - 4.3e-05 22.8 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 EEB07101.1 - 8.3e-05 22.8 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 EEB07101.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EEB07101.1 - 0.00012 22.0 0.1 0.00042 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEB07101.1 - 0.00084 19.3 0.3 0.073 13.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EEB07101.1 - 0.00094 19.2 0.1 0.0071 16.4 0.0 2.3 2 1 1 3 3 3 1 AAA domain DNA_pol3_delta PF06144.13 EEB07101.1 - 0.00099 18.9 0.1 0.0025 17.6 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 EEB07101.1 - 0.0011 18.8 0.0 0.0066 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEB07101.1 - 0.0012 19.1 1.2 0.2 11.9 0.2 3.3 2 2 1 3 3 3 1 AAA domain TniB PF05621.11 EEB07101.1 - 0.0014 18.1 0.1 0.015 14.7 0.1 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 EEB07101.1 - 0.0022 18.3 0.1 0.017 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEB07101.1 - 0.0053 16.6 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EEB07101.1 - 0.0077 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EEB07101.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 EEB07101.1 - 0.015 15.3 0.0 0.48 10.4 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EEB07101.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB07101.1 - 0.023 14.1 0.0 0.09 12.1 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EEB07101.1 - 0.043 13.7 0.8 0.12 12.2 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DEAD PF00270.29 EEB07101.1 - 0.06 13.1 0.2 0.37 10.6 0.3 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 EEB07101.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EEB07101.1 - 0.12 11.4 0.0 0.57 9.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EEB07101.1 - 0.12 12.0 0.0 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TPR_6 PF13174.6 EEB07101.1 - 0.3 11.8 0.8 33 5.4 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat HATPase_c PF02518.26 EEB07102.1 - 1.9e-28 99.2 0.0 1.3e-27 96.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEB07102.1 - 1.8e-20 73.1 0.1 4.6e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EEB07102.1 - 1.4e-18 66.7 0.1 4.7e-18 65.0 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EEB07102.1 - 8.7e-07 29.2 0.0 3.7e-06 27.1 0.0 2.2 1 0 0 1 1 1 1 PAS domain Pkinase PF00069.25 EEB07102.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PAS PF00989.25 EEB07102.1 - 2.9e-06 27.3 0.0 7.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold AAA_16 PF13191.6 EEB07102.1 - 5.9e-06 26.8 0.0 2.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PAS_4 PF08448.10 EEB07102.1 - 5.7e-05 23.3 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold NACHT PF05729.12 EEB07102.1 - 0.00098 19.1 0.0 0.0065 16.4 0.0 2.5 2 1 0 2 2 1 1 NACHT domain GAF_3 PF13492.6 EEB07102.1 - 0.0022 18.4 0.0 0.008 16.5 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 EEB07102.1 - 0.0032 17.8 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.7 EEB07102.1 - 0.0056 16.7 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain GAF PF01590.26 EEB07102.1 - 0.041 14.5 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 1 0 GAF domain HATPase_c_3 PF13589.6 EEB07102.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_12 PF18400.1 EEB07102.1 - 1.3 8.9 4.0 7.2 6.4 0.1 3.3 3 0 0 3 3 3 0 Thioredoxin-like domain Ribosomal_S2 PF00318.20 EEB07103.1 - 9.4e-27 93.6 0.3 9.2e-16 57.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EEB07103.1 - 0.00054 21.3 11.6 0.0013 20.1 11.6 1.7 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MMS1_N PF10433.9 EEB07104.1 - 4e-129 431.4 0.1 6.2e-129 430.8 0.1 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEB07104.1 - 8.5e-78 261.9 0.1 8.3e-77 258.6 0.0 2.3 2 1 0 2 2 2 1 CPSF A subunit region ANAPC4 PF12896.7 EEB07105.1 - 1.1e-53 181.8 2.1 1.7e-53 181.2 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EEB07105.1 - 2.4e-25 88.6 0.1 5.9e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain MutL_C PF08676.11 EEB07106.2 - 1.3e-25 89.9 0.0 2.7e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EEB07106.2 - 1.7e-12 47.4 0.1 3.3e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EEB07106.2 - 2.8e-10 39.9 0.0 7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EEB07106.2 - 1e-06 29.2 0.1 2.1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase eIF-5a PF01287.20 EEB07108.1 - 1.4e-28 98.8 0.2 1.9e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EEB07108.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.22 EEB07110.1 - 2.8e-21 76.6 0.0 4.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEB07110.1 - 1.5e-16 60.4 0.0 2.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EEB07110.1 - 8e-06 26.5 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EEB07110.1 - 0.014 15.9 0.0 0.063 13.7 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EEB07110.1 - 0.066 13.9 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_17 PF00332.18 EEB07111.1 - 5.9e-49 167.3 0.2 9.5e-49 166.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Lung_7-TM_R PF06814.13 EEB07112.1 - 1.4e-59 201.8 26.8 1.7e-59 201.5 26.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF656 PF04920.12 EEB07112.1 - 0.086 12.8 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF656) Glyco_hydro_2_N PF02837.18 EEB07112.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain LRR19-TM PF15176.6 EEB07112.1 - 0.75 9.8 4.7 19 5.3 0.5 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain POT1 PF02765.17 EEB07113.1 - 4.1e-22 78.6 0.0 1.1e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 EEB07113.1 - 9.4e-18 64.6 0.1 2.5e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein REPA_OB_2 PF16900.5 EEB07113.1 - 0.003 17.4 0.0 0.039 13.9 0.0 2.7 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EEB07113.1 - 0.14 12.2 0.3 6.8 6.8 0.0 3.0 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Prefoldin_2 PF01920.20 EEB07114.1 - 0.011 15.6 1.1 0.011 15.6 1.1 2.8 2 1 1 3 3 3 0 Prefoldin subunit Aminotran_4 PF01063.19 EEB07114.1 - 0.045 13.6 0.5 0.076 12.9 0.5 1.3 1 0 0 1 1 1 0 Amino-transferase class IV IF-2B PF01008.17 EEB07114.1 - 0.062 12.5 2.1 0.088 12.0 1.7 1.5 1 1 0 1 1 1 0 Initiation factor 2 subunit family KIX_2 PF16987.5 EEB07114.1 - 0.13 12.3 1.7 2.3 8.3 0.0 2.9 2 1 0 2 2 2 0 KIX domain bZIP_1 PF00170.21 EEB07114.1 - 0.26 11.4 8.1 2.1 8.5 1.7 2.9 2 0 0 2 2 2 0 bZIP transcription factor GIT_CC PF16559.5 EEB07114.1 - 8.6 6.3 9.6 8.4 6.3 0.3 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TIG PF01833.24 EEB07115.1 - 3.4e-15 55.9 3.7 1.3e-14 54.1 3.2 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 EEB07115.1 - 5e-10 39.4 0.3 1.3e-09 38.1 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EEB07115.1 - 4.6e-08 33.2 0.3 0.00071 19.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EEB07115.1 - 1.1e-07 32.3 0.1 3.4e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEB07115.1 - 5.5e-07 29.4 0.0 0.049 14.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EEB07115.1 - 6.5e-05 23.4 0.0 0.00032 21.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Arm PF00514.23 EEB07116.1 - 8.7e-15 54.2 1.4 0.093 12.8 0.0 9.0 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EEB07116.1 - 2.4e-09 36.7 3.3 0.02 15.1 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EEB07116.1 - 8.1e-08 32.5 0.0 0.24 11.8 0.0 5.0 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EEB07116.1 - 0.0046 17.0 10.9 0.067 13.2 1.0 5.4 4 3 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEB07116.1 - 0.012 16.1 3.3 8.3 7.0 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 EEB07116.1 - 0.22 11.7 2.9 6.4 7.0 0.1 4.3 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 WD40 PF00400.32 EEB07117.1 - 2.8e-22 78.6 9.4 0.0001 23.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07117.1 - 7.2e-11 42.2 0.0 0.00043 20.5 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB07117.1 - 0.00013 21.9 0.1 0.056 13.3 0.0 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EEB07117.1 - 0.0079 16.0 0.3 0.0079 16.0 0.3 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 EEB07117.1 - 0.043 13.8 7.8 1.8 8.6 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pyocin_S PF06958.12 EEB07117.1 - 0.14 12.7 0.3 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 S-type Pyocin WD40_like PF17005.5 EEB07117.1 - 0.21 10.9 0.2 2.6 7.3 0.1 2.5 3 0 0 3 3 3 0 WD40-like domain MgsA_C PF12002.8 EEB07118.2 - 1.5e-57 194.2 0.1 3.3e-57 193.1 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EEB07118.2 - 4e-23 81.6 0.0 1.1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EEB07118.2 - 2.4e-15 57.1 0.1 4.7e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEB07118.2 - 2.9e-14 53.1 0.0 5.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEB07118.2 - 1.3e-07 31.7 0.1 3.5e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB07118.2 - 1.1e-06 29.2 0.1 0.0018 18.7 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 EEB07118.2 - 5.9e-06 26.3 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EEB07118.2 - 1e-05 25.3 0.1 0.025 14.3 0.0 2.3 1 1 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 EEB07118.2 - 6.5e-05 22.2 0.2 0.02 14.1 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EEB07118.2 - 0.00014 22.2 0.1 0.00077 19.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EEB07118.2 - 0.00069 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EEB07118.2 - 0.0017 17.6 0.0 0.004 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) zf_UBZ PF18439.1 EEB07118.2 - 0.0018 17.9 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger TIP49 PF06068.13 EEB07118.2 - 0.0018 17.6 0.1 0.006 15.8 0.0 1.6 1 1 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 EEB07118.2 - 0.0036 17.2 0.3 4 7.3 0.2 2.8 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea zf-Di19 PF05605.12 EEB07118.2 - 0.0088 16.3 0.5 0.017 15.4 0.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Mg_chelatase PF01078.21 EEB07118.2 - 0.0093 15.4 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EEB07118.2 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EEB07118.2 - 0.012 16.2 0.0 0.035 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EEB07118.2 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEB07118.2 - 0.028 14.2 0.2 0.077 12.8 0.2 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 EEB07118.2 - 0.03 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EEB07118.2 - 0.036 14.2 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEB07118.2 - 0.039 14.5 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EEB07118.2 - 0.04 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEB07118.2 - 0.048 14.0 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 EEB07118.2 - 0.069 13.1 0.2 2.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 EEB07118.2 - 0.076 13.1 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase NACHT PF05729.12 EEB07118.2 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DEAD PF00270.29 EEB07119.1 - 2.2e-27 95.9 0.0 4.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EEB07119.1 - 2e-16 60.5 1.3 8.1e-16 58.6 1.3 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EEB07119.1 - 3.9e-15 56.1 0.1 1.2e-12 48.1 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07119.1 - 3.5e-07 30.4 0.0 7.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EEB07119.1 - 0.021 15.1 0.9 0.029 14.7 0.1 1.6 2 0 0 2 2 2 0 DNA replication factor CDT1 like DUF4264 PF14084.6 EEB07119.1 - 0.19 11.4 1.5 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Mit_ribos_Mrp51 PF11709.8 EEB07120.1 - 7.6e-17 61.9 0.3 2.2e-16 60.4 0.1 1.8 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit SH3_9 PF14604.6 EEB07121.1 - 9.3e-09 35.0 0.2 1.9e-08 34.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB07121.1 - 1.9e-07 30.7 0.0 5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EEB07121.1 - 2e-07 30.5 0.1 4e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain RPAP2_Rtr1 PF04181.13 EEB07122.1 - 1.9e-16 60.2 1.6 3.9e-16 59.1 1.6 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Arch_fla_DE PF04659.13 EEB07122.1 - 0.0067 16.3 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 Archaeal flagella protein LMBR1 PF04791.16 EEB07122.1 - 0.51 9.2 1.4 0.5 9.2 1.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec20 PF03908.13 EEB07123.1 - 1.1e-21 76.6 1.8 1.1e-21 76.6 1.8 2.0 2 1 0 2 2 2 1 Sec20 LMBR1 PF04791.16 EEB07123.1 - 0.014 14.4 0.4 0.015 14.2 0.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PP2C_C PF07830.13 EEB07123.1 - 0.062 13.8 0.1 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Baculo_11_kDa PF06143.11 EEB07123.1 - 0.076 12.6 3.1 0.079 12.5 0.3 2.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family Cys_Met_Meta_PP PF01053.20 EEB07124.1 - 1.4e-65 221.4 0.3 5e-65 219.5 0.3 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEB07124.1 - 0.0048 16.1 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEB07124.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V tRNA_synthFbeta PF17759.1 EEB07126.1 - 1.1e-47 162.2 0.0 1.5e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EEB07126.1 - 1.5e-29 102.0 0.3 2.5e-27 94.9 0.0 2.7 2 1 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EEB07126.1 - 2.1e-25 89.4 0.0 3.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EEB07126.1 - 2.2e-16 59.9 0.0 7.1e-16 58.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase B5 domain Ribosomal_L13 PF00572.18 EEB07127.1 - 3.2e-11 43.6 0.1 3e-09 37.2 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 SecY PF00344.20 EEB07128.2 - 6.8e-36 124.1 8.2 9.5e-36 123.6 8.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EEB07128.2 - 6.9e-08 32.2 0.5 3e-07 30.2 0.0 2.4 3 0 0 3 3 3 1 Plug domain of Sec61p Med26 PF08711.11 EEB07129.1 - 4.4e-12 45.8 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.9 EEB07130.1 - 8.5e-13 48.1 1.3 9.6e-13 47.9 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EEB07131.1 - 3.3e-41 140.7 3.1 3.3e-41 140.7 3.1 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EEB07131.1 - 0.03 15.1 37.4 0.03 15.1 37.4 3.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region AATF-Che1 PF13339.6 EEB07131.1 - 0.27 11.9 3.8 0.82 10.4 1.7 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor MbeD_MobD PF04899.12 EEB07131.1 - 0.39 10.9 3.0 10 6.3 0.2 3.5 2 1 1 3 3 3 0 MbeD/MobD like COG5 PF10392.9 EEB07132.1 - 1.7e-20 73.5 0.6 1.7e-20 73.5 0.6 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 EEB07132.1 - 0.0044 16.3 0.3 0.0044 16.3 0.3 1.8 2 1 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex THP2 PF09432.10 EEB07132.1 - 0.094 12.8 3.2 0.095 12.7 0.5 2.2 2 1 0 2 2 2 0 Tho complex subunit THP2 DUF3734 PF12536.8 EEB07132.1 - 0.14 12.5 1.7 6.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Patatin phospholipase Baculo_PEP_C PF04513.12 EEB07132.1 - 1.7 8.7 13.8 0.19 11.7 4.7 3.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 EEB07132.1 - 7.7 6.0 8.9 74 2.8 8.8 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit TRF PF08558.10 EEB07133.1 - 2e-64 217.5 0.0 2.7e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EEB07133.1 - 2.9e-06 27.4 0.3 6e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB07133.1 - 0.00067 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.14 EEB07133.1 - 0.037 14.7 0.9 0.27 11.9 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function, DUF573 PAT1 PF09770.9 EEB07134.1 - 7.6e-180 600.2 6.4 1.1e-151 507.1 0.8 2.3 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Peptidase_C48 PF02902.19 EEB07135.1 - 1.4e-44 152.6 0.0 2.6e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 EEB07135.1 - 0.038 12.7 0.1 0.059 12.1 0.1 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Arrestin_C PF02752.22 EEB07136.1 - 1.7e-07 31.8 6.8 2.2e-07 31.4 0.5 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain UPF0300 PF08594.10 EEB07137.1 - 2.4e-37 128.3 0.3 4.3e-37 127.5 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) PPR_2 PF13041.6 EEB07138.1 - 6.7e-29 99.8 7.6 6e-14 52.0 0.1 7.3 5 1 3 8 8 8 4 PPR repeat family PPR PF01535.20 EEB07138.1 - 2.1e-17 62.1 6.2 4.3e-05 23.5 0.0 6.5 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 EEB07138.1 - 1.5e-07 31.4 3.8 0.0022 18.0 0.1 4.5 3 1 3 6 6 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EEB07138.1 - 1.3e-06 28.0 0.1 0.18 11.5 0.0 4.5 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EEB07138.1 - 4.1e-06 26.3 2.3 0.00014 21.3 0.1 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF4709 PF15821.5 EEB07138.1 - 0.31 11.4 2.0 1.3 9.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) SIX1_SD PF16878.5 EEB07138.1 - 0.31 11.6 3.7 3.9 8.0 1.7 3.2 2 1 1 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain SRF-TF PF00319.18 EEB07139.1 - 1.5e-19 69.2 0.0 2.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glucan_synthase PF02364.15 EEB07140.1 - 0 1280.5 0.0 0 1279.6 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEB07140.1 - 2.6e-39 134.5 1.9 9e-39 132.8 1.9 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 BaxI_1 PF12811.7 EEB07140.1 - 2.4 7.7 14.8 0.035 13.7 6.0 2.4 3 0 0 3 3 3 0 Bax inhibitor 1 like SprT-like PF10263.9 EEB07141.1 - 1.8e-30 105.1 1.9 3.5e-30 104.1 0.1 2.1 2 0 0 2 2 2 1 SprT-like family HMG_box PF00505.19 EEB07141.1 - 7.1e-07 29.6 0.2 2.8e-06 27.6 0.2 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 EEB07141.1 - 0.00011 22.8 0.2 0.00011 22.8 0.2 2.6 2 2 0 2 2 2 1 YABBY protein Ccdc124 PF06244.12 EEB07141.1 - 0.0018 18.8 1.6 0.0053 17.3 1.2 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Peptidase_M91 PF14891.6 EEB07141.1 - 0.089 13.1 0.2 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Effector protein Ribosomal_S30 PF04758.14 EEB07142.1 - 7.4e-29 99.7 5.0 8e-29 99.6 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_4 PF01063.19 EEB07143.1 - 1.1e-29 103.9 0.0 1.6e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV MutS_V PF00488.21 EEB07144.1 - 6.7e-82 274.1 0.2 1.1e-81 273.3 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEB07144.1 - 1.3e-33 116.8 1.2 2.8e-33 115.8 0.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EEB07144.1 - 7.8e-21 74.2 0.2 2e-20 72.9 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EEB07144.1 - 6.3e-17 62.1 0.2 4.4e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 EEB07144.1 - 1e-11 45.0 0.0 3.8e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain I Paf1 PF03985.13 EEB07144.1 - 0.029 13.4 0.6 0.044 12.8 0.0 1.5 2 0 0 2 2 2 0 Paf1 Rad17 PF03215.15 EEB07144.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain G10 PF01125.17 EEB07145.1 - 1.3e-66 222.9 3.7 1.5e-66 222.7 3.7 1.0 1 0 0 1 1 1 1 G10 protein DUF2013 PF09431.10 EEB07146.1 - 5.3e-43 146.5 3.2 2.5e-42 144.3 0.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) COX6B PF02297.17 EEB07147.1 - 6.7e-21 74.3 3.7 8.5e-21 74.0 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb XFP_N PF09364.10 EEB07148.1 - 2.6e-157 523.3 0.0 3.4e-157 522.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EEB07148.1 - 4.6e-72 241.7 0.0 6.5e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EEB07148.1 - 3.4e-71 238.6 0.0 5.3e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EEB07148.1 - 0.037 13.8 0.1 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Folliculin PF11704.8 EEB07149.2 - 2.1e-43 148.4 0.0 3.3e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SPX PF03105.19 EEB07149.2 - 2.7 7.8 6.2 0.55 10.1 0.1 2.1 2 0 0 2 2 2 0 SPX domain CDC14 PF08045.11 EEB07150.1 - 6.8e-40 136.9 2.2 1.1e-30 106.7 0.7 3.0 1 1 2 3 3 3 3 Cell division control protein 14, SIN component G-alpha PF00503.20 EEB07151.1 - 2.9e-94 316.2 0.0 3.5e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEB07151.1 - 8.7e-12 44.8 0.1 7.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EEB07151.1 - 0.0027 17.9 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EEB07151.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 EEB07151.1 - 0.055 12.8 0.2 6.2 6.1 0.2 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB07151.1 - 0.15 12.1 0.0 23 5.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Coatomer_E PF04733.14 EEB07152.1 - 1.5e-42 146.0 2.9 2.2e-42 145.4 2.9 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EEB07152.1 - 0.0012 19.3 1.6 0.0012 19.3 1.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEB07152.1 - 0.046 14.5 1.1 2.4 9.2 0.1 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Aldedh PF00171.22 EEB07153.1 - 5.5e-108 361.4 0.0 6.7e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2b PF00587.25 EEB07154.1 - 7.3e-31 107.5 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEB07154.1 - 3.7e-10 39.8 0.0 1.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain MID_MedPIWI PF18296.1 EEB07155.2 - 0.056 13.2 3.0 0.08 12.7 3.0 1.2 1 0 0 1 1 1 0 MID domain of medPIWI GAGE PF05831.11 EEB07155.2 - 0.085 13.4 4.4 0.17 12.5 4.4 1.7 1 1 0 1 1 1 0 GAGE protein DUF2666 PF10869.8 EEB07155.2 - 0.089 13.0 0.6 0.15 12.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Ubiq_cyt_C_chap PF03981.12 EEB07155.2 - 0.12 12.4 0.1 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone KELK PF15796.5 EEB07155.2 - 0.86 10.1 5.2 21 5.7 4.3 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TFIIA PF03153.13 EEB07156.1 - 0.77 9.7 21.2 0.96 9.4 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PUF PF00806.19 EEB07157.1 - 4.3e-53 174.1 11.3 4.4e-08 32.4 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EEB07157.1 - 0.0018 18.6 2.7 0.07 13.5 0.8 3.0 2 1 2 4 4 4 1 CPL (NUC119) domain RasGEF PF00617.19 EEB07157.1 - 0.16 12.2 0.7 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 RasGEF domain fn3_2 PF16893.5 EEB07159.2 - 7.8e-36 122.1 0.0 1.3e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EEB07159.2 - 1.2e-21 76.3 0.3 2.1e-21 75.6 0.3 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EEB07159.2 - 5.6e-08 33.1 0.0 9.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEB07159.2 - 1.3e-07 31.4 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 EEB07159.2 - 0.0012 19.0 0.1 0.0079 16.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EEB07159.2 - 0.013 15.8 0.0 0.046 14.1 0.0 2.0 1 0 0 1 1 1 0 Fibronectin type III domain Chorion_2 PF03964.15 EEB07159.2 - 0.29 12.0 4.6 6 7.8 0.1 2.7 2 0 0 2 2 2 0 Chorion family 2 Synaptobrevin PF00957.21 EEB07160.1 - 9.5e-34 115.1 2.3 1.1e-33 114.9 2.3 1.1 1 0 0 1 1 1 1 Synaptobrevin NPV_P10 PF05531.12 EEB07160.1 - 0.034 14.6 0.3 0.055 13.9 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 EEB07160.1 - 0.097 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_11 PF13086.6 EEB07161.1 - 5.8e-72 242.6 0.5 5.8e-72 242.6 0.5 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EEB07161.1 - 1.1e-61 208.0 0.5 3.4e-61 206.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain SEN1_N PF12726.7 EEB07161.1 - 6.6e-30 104.0 23.4 7.2e-20 70.8 10.3 3.1 3 0 0 3 3 3 2 SEN1 N terminal AAA_30 PF13604.6 EEB07161.1 - 7.4e-09 35.6 0.0 0.00074 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEB07161.1 - 2.9e-08 34.2 0.0 2.3e-07 31.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEB07161.1 - 3.3e-06 27.0 0.1 0.56 9.9 0.0 4.1 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EEB07161.1 - 0.0024 17.8 0.2 0.16 11.8 0.0 2.8 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EEB07161.1 - 0.014 15.7 2.3 3.6 7.9 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 EEB07161.1 - 0.02 15.3 1.9 0.47 10.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EEB07161.1 - 0.09 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EEB07161.1 - 0.67 9.4 14.8 0.064 12.8 1.6 3.5 3 2 1 4 4 3 0 UvrD/REP helicase N-terminal domain Ribosomal_L24e PF01246.20 EEB07162.1 - 4.5e-30 103.7 0.1 4.5e-30 103.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e ISG65-75 PF11727.8 EEB07162.1 - 0.14 11.4 11.9 0.18 11.0 11.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein UCH PF00443.29 EEB07163.1 - 3.3e-46 157.9 0.2 4.3e-46 157.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EEB07163.1 - 4.5e-14 52.0 0.0 1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 EEB07163.1 - 4.5e-12 46.2 3.9 8.5e-09 35.4 3.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 EEB07163.1 - 0.00032 20.6 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain ARPC4 PF05856.12 EEB07164.1 - 1e-73 246.5 3.6 1.1e-73 246.3 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Cnn_1N PF07989.11 EEB07165.1 - 2e-20 72.7 12.1 2e-20 72.7 12.1 15.3 5 3 7 13 13 13 4 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EEB07165.1 - 2.2e-19 69.8 0.3 2.2e-19 69.8 0.3 5.3 5 1 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Tropomyosin PF00261.20 EEB07165.1 - 0.0014 18.1 38.4 0.0014 18.1 38.4 7.0 3 2 3 7 7 7 2 Tropomyosin DUF5085 PF16895.5 EEB07165.1 - 0.24 11.7 6.9 0.056 13.8 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5085) Spc7 PF08317.11 EEB07165.1 - 1.6 7.6 190.3 0.0093 14.9 23.1 9.1 1 1 8 10 10 10 0 Spc7 kinetochore protein NUDIX PF00293.28 EEB07166.1 - 1.5e-10 41.2 0.0 2.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.20 EEB07167.1 - 4.8e-13 49.2 2.1 4.8e-13 49.2 2.1 1.9 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 EEB07167.1 - 0.037 14.4 1.8 0.055 13.8 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain T6PP_N PF18572.1 EEB07167.1 - 0.067 13.0 4.1 17 5.4 0.0 2.9 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Pkinase PF00069.25 EEB07168.1 - 2.6e-71 240.1 0.0 3e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07168.1 - 1e-35 123.3 0.0 1.3e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07168.1 - 4e-09 36.2 0.1 8.9e-06 25.2 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EEB07168.1 - 1.5e-06 27.7 0.1 2.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB07168.1 - 1.5e-05 24.0 0.0 2.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB07168.1 - 0.14 12.0 0.1 0.47 10.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PUF PF00806.19 EEB07169.1 - 4.6e-22 76.4 0.0 0.0054 16.4 0.1 8.6 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat DUF1764 PF08576.10 EEB07170.1 - 3e-23 82.6 7.6 4.6e-23 82.0 7.6 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) zf-C2H2 PF00096.26 EEB07171.1 - 1.3e-11 44.3 18.0 2.7e-05 24.4 3.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEB07171.1 - 3e-08 33.7 8.2 0.00069 19.9 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEB07171.1 - 2.1e-07 31.2 14.4 0.0051 17.5 2.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEB07171.1 - 2.7e-07 30.4 4.5 0.0048 16.9 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEB07171.1 - 0.0025 17.5 4.7 0.0087 15.8 1.1 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2HE PF16278.5 EEB07171.1 - 0.15 12.5 4.8 0.3 11.6 0.5 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 EEB07171.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEB07171.1 - 0.73 10.3 8.1 0.74 10.3 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 EEB07171.1 - 2.2 8.1 8.4 0.25 11.1 1.7 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ubiquitin PF00240.23 EEB07172.1 - 6.8e-34 115.5 0.5 6.8e-34 115.5 0.5 1.8 2 1 1 3 3 3 1 Ubiquitin family Ribosomal_S27 PF01599.19 EEB07172.1 - 2.5e-25 88.3 2.5 2.5e-25 88.3 2.5 1.8 2 0 0 2 2 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EEB07172.1 - 1.7e-16 59.8 0.6 1.7e-16 59.8 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB07172.1 - 1.2e-05 25.7 0.4 0.00018 21.9 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB07172.1 - 0.00059 19.9 0.5 0.0013 18.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EEB07172.1 - 0.0047 17.3 0.5 0.0093 16.3 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB07172.1 - 0.0056 16.6 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EEB07172.1 - 0.0079 16.7 0.7 0.011 16.2 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EEB07172.1 - 0.024 14.7 1.0 5.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Zn_Tnp_IS1595 PF12760.7 EEB07172.1 - 0.036 14.0 1.5 0.06 13.3 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 EEB07172.1 - 0.038 14.0 0.5 0.11 12.6 0.5 1.6 1 1 1 2 2 2 0 Double zinc ribbon DUF4925 PF16272.5 EEB07172.1 - 0.039 13.4 0.1 0.054 13.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) Nudix_N_2 PF14803.6 EEB07172.1 - 0.045 13.7 2.0 0.11 12.5 1.3 2.0 1 1 1 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 EEB07172.1 - 0.12 12.3 1.0 0.29 11.1 1.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 EEB07172.1 - 0.27 11.2 2.7 0.91 9.5 2.7 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 EEB07172.1 - 0.33 10.7 3.8 1.3 8.8 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Plexin_cytopl PF08337.12 EEB07172.1 - 0.34 9.5 2.9 8.8 4.9 0.3 2.2 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain zf-ribbon_3 PF13248.6 EEB07172.1 - 1.2 8.6 4.7 0.31 10.5 0.4 2.0 2 0 0 2 2 2 0 zinc-ribbon domain ARID PF01388.21 EEB07173.1 - 2.5e-16 60.1 0.0 1.2e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EEB07173.1 - 0.0085 15.4 0.3 0.0085 15.4 0.3 2.6 3 1 0 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa pKID PF02173.17 EEB07173.1 - 0.16 11.5 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 pKID domain TerB_C PF15615.6 EEB07173.1 - 0.36 11.1 0.0 0.36 11.1 0.0 3.3 3 0 0 3 3 3 0 TerB-C domain BRF1 PF07741.13 EEB07173.1 - 0.8 10.1 12.8 0.3 11.5 4.7 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TERB2 PF15101.6 EEB07173.1 - 2.4 8.1 18.3 2.5 8.1 3.1 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Zip PF02535.22 EEB07173.1 - 2.5 7.2 6.9 2.1 7.5 0.8 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter MAT1 PF06391.13 EEB07173.1 - 3.5 7.4 14.7 2.7 7.8 4.1 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Med15 PF09606.10 EEB07173.1 - 3.7 6.1 72.3 0.064 11.9 19.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal LIM_bind PF01803.16 EEB07174.1 - 1.6e-50 171.9 1.5 1.6e-50 171.9 1.5 2.2 2 1 0 2 2 2 1 LIM-domain binding protein R3H PF01424.22 EEB07175.1 - 1.7e-14 53.5 0.4 6.1e-14 51.8 0.1 2.1 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 EEB07175.1 - 2.4e-07 30.5 1.6 4.5e-07 29.7 1.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEB07175.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.2 2 0 0 2 2 2 0 G-patch domain WSC PF01822.19 EEB07176.1 - 2.6e-12 46.8 8.7 2.6e-12 46.8 8.7 2.9 2 1 0 2 2 1 1 WSC domain Apt1 PF10351.9 EEB07176.1 - 0.00066 18.6 17.6 0.00081 18.4 17.6 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 EEB07176.1 - 0.0023 17.9 18.2 0.0032 17.5 18.2 1.3 1 0 0 1 1 1 1 SPX domain Utp14 PF04615.13 EEB07176.1 - 0.0048 15.6 1.6 0.0053 15.4 1.6 1.0 1 0 0 1 1 1 1 Utp14 protein TMEM154 PF15102.6 EEB07176.1 - 0.0076 16.2 3.0 0.0076 16.2 3.0 2.5 1 1 1 2 2 1 1 TMEM154 protein family DUF4551 PF15087.6 EEB07176.1 - 0.031 13.1 9.4 0.036 12.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 EEB07176.1 - 0.038 13.2 30.5 0.048 12.9 30.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 EEB07176.1 - 0.17 11.7 9.9 0.47 10.3 9.9 1.6 1 1 0 1 1 1 0 Rifin Syndecan PF01034.20 EEB07176.1 - 0.57 10.1 1.5 1.3 8.9 1.5 1.6 1 0 0 1 1 1 0 Syndecan domain DUF572 PF04502.13 EEB07176.1 - 0.65 9.6 11.1 0.81 9.3 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MAGE PF01454.19 EEB07176.1 - 0.94 9.1 4.7 1.6 8.4 4.7 1.3 1 0 0 1 1 1 0 MAGE family Plasmodium_Vir PF05795.11 EEB07176.1 - 1.7 8.0 14.0 2.4 7.5 14.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Smg8_Smg9 PF10220.9 EEB07176.1 - 1.7 6.9 9.2 2 6.7 9.2 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SKG6 PF08693.10 EEB07176.1 - 4.5 6.8 10.9 0.14 11.6 2.6 2.9 2 0 0 2 2 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 EEB07176.1 - 6.7 5.4 9.8 0.049 12.5 0.4 2.0 2 1 1 3 3 3 0 Amnionless Asp PF00026.23 EEB07177.1 - 5.9e-63 213.2 14.3 5.9e-63 213.2 14.3 1.6 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEB07177.1 - 4.7e-15 56.3 0.4 3.7e-14 53.4 0.4 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EEB07177.1 - 0.024 14.4 3.0 0.25 11.1 0.0 3.2 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EEB07177.1 - 0.26 12.0 11.1 1.4 9.6 0.0 4.3 4 1 1 5 5 5 0 Aspartyl protease LAMTOR PF15454.6 EEB07177.1 - 0.28 11.8 1.9 0.72 10.5 1.9 1.6 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HhH-GPD PF00730.25 EEB07178.1 - 4.2e-16 59.4 0.0 8.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EEB07178.1 - 1.1e-13 51.2 0.0 2.2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 EEB07178.1 - 8.4e-07 28.6 0.1 1.6e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif TEA PF01285.18 EEB07178.1 - 0.027 14.5 0.0 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 TEA/ATTS domain DUF3665 PF12427.8 EEB07178.1 - 0.14 11.9 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase RasGEF_N_2 PF14663.6 EEB07178.1 - 0.27 11.7 2.1 10 6.5 0.1 3.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RMI1_N PF08585.12 EEB07179.1 - 2.7e-47 161.3 0.0 3.2e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein DUF4035 PF13227.6 EEB07179.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) tRNA_bind PF01588.20 EEB07180.1 - 2.4e-26 91.7 0.1 4.8e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF913 PF06025.12 EEB07180.1 - 0.023 13.7 0.4 0.029 13.3 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Menin PF05053.13 EEB07180.1 - 0.091 11.1 3.9 0.12 10.7 3.9 1.1 1 0 0 1 1 1 0 Menin GST_C PF00043.25 EEB07180.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.0 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain NARP1 PF12569.8 EEB07180.1 - 0.42 9.5 12.0 0.59 9.0 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 EEB07180.1 - 1.7 9.0 13.3 3.3 8.1 13.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF5427 PF10310.9 EEB07180.1 - 3.3 6.6 14.7 5.2 5.9 14.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 EEB07180.1 - 5.2 5.7 5.6 7.4 5.2 5.6 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EEB07180.1 - 8.5 5.0 9.3 13 4.5 9.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cornichon PF03311.14 EEB07181.1 - 1e-44 151.8 10.1 1.2e-44 151.5 10.1 1.0 1 0 0 1 1 1 1 Cornichon protein Tubulin_3 PF14881.6 EEB07182.1 - 5.5e-34 117.4 0.2 9.4e-34 116.7 0.2 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EEB07182.1 - 5e-30 104.2 0.0 1.1e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EEB07182.1 - 0.047 13.9 0.0 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain DBC1 PF14443.6 EEB07182.1 - 0.11 12.5 0.0 0.52 10.3 0.0 1.9 1 1 1 2 2 2 0 DBC1 14-3-3 PF00244.20 EEB07183.1 - 4.6e-105 350.0 6.4 6e-105 349.7 6.4 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF3802 PF12290.8 EEB07183.1 - 0.11 13.0 0.6 0.8 10.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) Rad51 PF08423.11 EEB07184.2 - 2.5e-110 367.8 0.1 3.1e-110 367.4 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EEB07184.2 - 3e-15 56.4 0.1 4.2e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EEB07184.2 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EEB07184.2 - 3.4e-06 26.6 0.2 7.2e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 EEB07184.2 - 0.00012 22.6 0.3 0.00026 21.5 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 EEB07184.2 - 0.023 14.0 0.1 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 AAA_24 PF13479.6 EEB07184.2 - 0.097 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Abhydrolase_2 PF02230.16 EEB07185.1 - 7.1e-65 218.9 0.0 8.4e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EEB07185.1 - 3.7e-06 26.4 0.1 0.13 11.5 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEB07185.1 - 0.00088 19.0 0.4 0.024 14.3 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold FSH1 PF03959.13 EEB07185.1 - 0.00093 18.9 0.0 0.0046 16.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EEB07185.1 - 0.011 16.4 0.0 0.015 16.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 EEB07185.1 - 0.28 10.2 0.4 17 4.4 0.1 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF5102 PF17104.5 EEB07186.1 - 4.9e-37 128.5 3.7 8.9e-20 71.9 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF5102) TBCA PF02970.16 EEB07187.1 - 1.5e-17 63.7 2.0 1.7e-17 63.5 1.3 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Phage_Gp23 PF10669.9 EEB07187.1 - 0.072 13.4 3.1 0.097 13.0 2.8 1.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4287 PF14117.6 EEB07188.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) RrnaAD PF00398.20 EEB07188.1 - 0.079 12.0 0.0 0.25 10.4 0.0 1.8 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 EEB07188.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_25 PF13649.6 EEB07188.1 - 0.16 12.7 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Nsp1_C PF05064.13 EEB07190.1 - 1.2e-35 121.8 3.4 2.5e-35 120.8 3.4 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF16 PF01519.16 EEB07190.1 - 0.001 19.6 1.0 0.036 14.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 EEB07190.1 - 0.0029 18.0 1.1 0.4 11.1 0.6 2.3 2 0 0 2 2 2 1 Snapin/Pallidin Laminin_II PF06009.12 EEB07190.1 - 0.097 12.7 2.8 12 6.0 0.0 2.6 1 1 0 2 2 2 0 Laminin Domain II ALIX_LYPXL_bnd PF13949.6 EEB07190.1 - 0.1 11.9 2.8 0.31 10.3 2.9 1.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Sec34 PF04136.15 EEB07190.1 - 0.2 11.5 4.7 6.7 6.6 3.1 2.4 1 1 0 2 2 2 0 Sec34-like family FlaC_arch PF05377.11 EEB07190.1 - 0.45 11.0 2.4 59 4.2 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EEB07190.1 - 0.46 10.5 5.8 0.76 9.8 3.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EEB07190.1 - 0.64 10.5 5.6 4.8 7.7 0.1 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EEB07190.1 - 0.68 10.0 1.9 7.5 6.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EEB07190.1 - 3.5 7.7 5.1 7.9 6.6 0.9 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1748 PF08520.10 EEB07191.1 - 2e-26 91.7 0.0 2.2e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) XRN_M PF17846.1 EEB07192.1 - 2.7e-147 491.3 0.1 3.8e-146 487.5 0.1 2.2 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EEB07192.1 - 2.3e-96 321.9 0.0 8.5e-96 320.1 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CN_hydrolase PF00795.22 EEB07193.1 - 6.5e-66 222.3 0.0 7.5e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_5 PF13854.6 EEB07193.1 - 0.018 15.0 0.1 0.066 13.2 0.0 1.9 2 0 0 2 2 2 0 Kelch motif DUF5091 PF17012.5 EEB07193.1 - 0.086 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5091) ArfGap PF01412.18 EEB07194.1 - 3.2e-33 114.3 0.9 8.3e-33 112.9 0.9 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EEB07194.1 - 8.1e-12 45.4 0.5 2.1e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 EEB07194.1 - 3.2e-11 43.7 1.5 9.1e-11 42.2 0.8 2.2 2 0 0 2 2 2 1 PH domain ACDC PF14733.6 EEB07194.1 - 0.043 14.1 0.1 0.21 11.9 0.1 2.2 1 0 0 1 1 1 0 AP2-coincident C-terminal RhoGAP PF00620.27 EEB07195.1 - 2.9e-41 140.8 0.0 9.2e-41 139.2 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EEB07195.1 - 5.1e-06 27.0 0.0 2.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 PH domain MIP-T3_C PF17749.1 EEB07195.1 - 0.071 13.1 1.0 0.23 11.4 1.0 1.9 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region CortBP2 PF09727.9 EEB07195.1 - 0.73 9.7 10.9 1.3 8.8 5.6 2.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 LSM PF01423.22 EEB07196.1 - 2.5e-21 75.2 0.1 3e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB07196.1 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_L5_C PF00673.21 EEB07197.1 - 1e-21 76.9 0.0 1.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEB07197.1 - 3.7e-19 68.8 0.0 1.3e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EEB07197.1 - 0.043 13.5 0.5 0.075 12.8 0.1 1.6 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain WBS_methylT PF12589.8 EEB07198.1 - 4e-15 56.3 7.1 7.3e-15 55.5 7.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EEB07198.1 - 4.6e-13 49.6 0.0 9.9e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB07198.1 - 5e-12 46.4 0.0 1.3e-11 45.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB07198.1 - 2e-07 31.0 0.0 4.1e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB07198.1 - 3.4e-07 30.2 0.0 6.1e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB07198.1 - 7.5e-06 26.6 0.2 8.1e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EEB07198.1 - 0.00012 21.6 0.3 0.00031 20.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EEB07198.1 - 0.00036 19.9 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EEB07198.1 - 0.00067 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EEB07198.1 - 0.0013 18.7 0.4 0.3 11.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEB07198.1 - 0.0071 15.7 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family LidA_Long_CC PF18641.1 EEB07198.1 - 0.044 13.9 0.2 0.044 13.9 0.2 1.4 2 0 0 2 2 2 0 LidA long coiled-coil domain MTS PF05175.14 EEB07198.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 EEB07198.1 - 0.11 12.2 1.2 1.7 8.3 0.0 2.3 2 1 0 2 2 2 0 DNA methylase Clathrin PF00637.20 EEB07199.1 - 6.3e-198 648.6 43.3 2e-32 112.0 0.2 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EEB07199.1 - 3.4e-32 110.1 0.2 2.1e-31 107.6 0.1 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EEB07199.1 - 3.8e-24 83.8 0.7 9.7e-08 32.0 0.1 5.8 5 0 0 5 5 5 4 Clathrin propeller repeat Coatomer_WDAD PF04053.14 EEB07199.1 - 2.1e-06 27.0 4.0 0.0035 16.4 0.1 4.6 3 1 2 5 5 5 2 Coatomer WD associated region TPR_14 PF13428.6 EEB07199.1 - 2.4e-05 24.8 12.6 20 6.3 0.0 10.3 10 2 1 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEB07199.1 - 5.3e-05 23.0 4.6 16 5.8 0.0 7.8 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB07199.1 - 0.00036 20.4 3.5 3 8.2 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EEB07199.1 - 0.00037 19.8 0.1 0.00037 19.8 0.1 2.0 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 EEB07199.1 - 0.0061 16.3 2.9 6.1 6.8 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Vps39_1 PF10366.9 EEB07199.1 - 0.032 14.5 13.2 9.7 6.5 0.1 7.0 8 2 0 8 8 8 0 Vacuolar sorting protein 39 domain 1 PPR PF01535.20 EEB07199.1 - 0.097 13.0 2.7 56 4.3 0.1 5.6 6 0 0 6 6 5 0 PPR repeat NRBF2_MIT PF17169.4 EEB07199.1 - 0.13 12.5 0.5 40 4.5 0.1 3.6 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 ANAPC3 PF12895.7 EEB07199.1 - 0.47 10.7 10.1 14 6.0 0.3 5.7 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEB07199.1 - 0.48 10.8 11.8 0.58 10.5 0.0 6.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB07199.1 - 3.8 8.1 11.9 26 5.4 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 EEB07200.1 - 8.9e-52 174.3 0.8 1.1e-51 174.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Integrase_1 PF12835.7 EEB07201.2 - 0.099 12.7 0.0 19 5.4 0.0 2.4 2 0 0 2 2 2 0 Integrase HEAT_2 PF13646.6 EEB07202.1 - 7.3e-29 100.0 0.0 2.5e-12 47.0 0.0 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EEB07202.1 - 6.9e-27 91.4 0.0 9.6e-05 22.7 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EEB07202.1 - 3.1e-08 33.2 0.8 0.018 15.3 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 EEB07202.1 - 4.1e-05 23.5 0.0 0.024 14.7 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEB07202.1 - 4.7e-05 23.8 0.5 0.14 12.7 0.0 3.3 2 2 0 3 3 3 2 HEAT-like repeat Vitellogenin_N PF01347.22 EEB07202.1 - 0.043 12.2 0.0 7.2 4.9 0.0 3.1 3 0 0 3 3 3 0 Lipoprotein amino terminal region RuvA_C PF07499.13 EEB07202.1 - 0.68 10.4 3.5 1.8 9.1 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain AAA_6 PF12774.7 EEB07203.1 - 2.3e-106 355.5 0.1 2.3e-106 355.5 0.1 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EEB07203.1 - 2e-74 251.1 5.7 2e-74 251.1 5.7 4.8 5 1 0 5 5 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EEB07203.1 - 1.7e-58 198.6 13.0 1.7e-58 198.6 13.0 3.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 EEB07203.1 - 2e-39 135.0 1.4 8.4e-30 103.6 0.0 5.1 5 0 0 5 5 4 3 P-loop containing dynein motor region AAA_8 PF12780.7 EEB07203.1 - 1.6e-34 119.5 0.4 1.6e-34 119.5 0.4 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EEB07203.1 - 2e-33 115.4 5.2 2e-33 115.4 5.2 4.6 6 0 0 6 6 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EEB07203.1 - 7.3e-31 107.2 0.0 2.6e-30 105.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EEB07203.1 - 7.8e-31 106.9 0.0 1.2e-11 44.8 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) MT PF12777.7 EEB07203.1 - 1.7e-30 106.3 6.4 1.7e-30 106.3 6.4 3.4 4 0 0 4 4 3 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 EEB07203.1 - 2.7e-15 57.0 0.1 0.041 14.3 0.0 6.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EEB07203.1 - 2.5e-14 53.4 0.0 2.1e-13 50.4 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EEB07203.1 - 6.7e-14 52.3 0.7 0.0099 16.2 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 EEB07203.1 - 2.4e-08 34.5 2.1 0.1 13.0 0.0 6.3 6 0 0 6 6 5 1 AAA ATPase domain AAA_18 PF13238.6 EEB07203.1 - 1.2e-07 32.3 0.0 0.015 15.8 0.0 4.5 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EEB07203.1 - 1.3e-06 28.6 0.0 0.35 11.0 0.0 4.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EEB07203.1 - 1e-05 25.9 0.4 3.5 8.1 0.0 5.1 4 0 0 4 4 4 1 RNA helicase AAA_19 PF13245.6 EEB07203.1 - 2.5e-05 24.6 0.1 6.5 7.1 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EEB07203.1 - 9.2e-05 22.1 0.0 6.5 6.6 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EEB07203.1 - 0.00021 21.1 0.1 4.2 7.0 0.0 3.8 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EEB07203.1 - 0.00026 21.0 0.1 8.9 6.2 0.0 4.9 4 0 0 4 4 4 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EEB07203.1 - 0.00027 20.4 1.8 0.47 9.8 0.0 3.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI dNK PF01712.19 EEB07203.1 - 0.00087 19.2 0.4 0.5 10.2 0.0 4.0 2 0 0 2 2 2 1 Deoxynucleoside kinase MCM PF00493.23 EEB07203.1 - 0.00094 18.3 0.4 5.3 6.1 0.0 4.5 5 0 0 5 5 5 0 MCM P-loop domain BRE1 PF08647.11 EEB07203.1 - 0.0014 18.6 10.9 0.0014 18.6 10.9 4.4 4 0 0 4 4 2 1 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 EEB07203.1 - 0.0016 18.9 7.5 1.9 9.0 0.0 5.5 5 0 0 5 5 4 1 ABC transporter DUF815 PF05673.13 EEB07203.1 - 0.0018 17.4 0.0 1.9 7.6 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EEB07203.1 - 0.0023 17.7 0.4 5.1 6.8 0.1 3.8 4 0 0 4 4 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EEB07203.1 - 0.0074 16.0 0.1 12 5.6 0.0 4.1 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_lid_7 PF17867.1 EEB07203.1 - 0.0077 16.4 0.3 0.063 13.5 0.3 2.7 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_30 PF13604.6 EEB07203.1 - 0.0084 15.8 0.3 14 5.3 0.2 4.1 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 EEB07203.1 - 0.012 15.9 0.0 5.8 7.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EEB07203.1 - 0.028 14.4 0.5 5.9 6.9 0.0 3.9 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 EEB07203.1 - 0.034 13.5 0.0 8.6 5.6 0.1 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 EEB07203.1 - 0.042 13.8 0.5 4.4 7.2 0.1 3.4 3 0 0 3 3 2 0 NTPase MMR_HSR1 PF01926.23 EEB07203.1 - 0.05 13.7 0.0 0.28 11.3 0.0 2.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ERCC4 PF02732.15 EEB07203.1 - 0.085 13.1 7.7 1.3 9.2 2.3 3.7 3 0 0 3 3 3 0 ERCC4 domain AAA_25 PF13481.6 EEB07203.1 - 0.089 12.4 0.0 2.7 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEB07203.1 - 0.11 12.5 5.3 15 5.5 0.0 4.8 6 0 0 6 6 4 0 NACHT domain TRPM_tetra PF16519.5 EEB07203.1 - 0.22 11.6 1.4 17 5.6 0.1 4.4 5 0 0 5 5 2 0 Tetramerisation domain of TRPM AAA_17 PF13207.6 EEB07203.1 - 0.33 11.4 1.1 9.6 6.6 0.0 3.6 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 EEB07203.1 - 0.36 10.7 2.9 2.1 8.2 0.0 3.7 5 0 0 5 5 3 0 RsgA GTPase CENP-Q PF13094.6 EEB07203.1 - 5.1 7.3 17.8 1.8 8.8 2.2 3.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.9 EEB07203.1 - 7 6.9 6.7 10 6.4 2.6 3.5 2 0 0 2 2 2 0 Haemolysin XhlA DEAD PF00270.29 EEB07204.1 - 3.9e-46 157.0 0.0 7.7e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07204.1 - 4.6e-24 84.9 0.0 2.5e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEB07204.1 - 5.7e-20 71.3 0.0 1.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEB07204.1 - 8.1e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PolyA_pol PF01743.20 EEB07205.2 - 2e-26 92.9 0.0 3.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EEB07205.2 - 3.4e-09 36.3 0.0 6.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Syja_N PF02383.18 EEB07206.1 - 8.3e-74 248.8 0.0 2.3e-73 247.3 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain Meth_synt_2 PF01717.18 EEB07207.2 - 2.2e-151 503.7 0.0 9.4e-147 488.5 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EEB07207.2 - 1.7e-123 412.1 0.0 4.2e-117 391.1 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF5619 PF18505.1 EEB07207.2 - 0.082 12.9 0.0 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5619) Steroid_dh PF02544.16 EEB07208.1 - 7.9e-33 113.6 4.3 6.4e-26 91.1 1.7 2.3 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EEB07208.1 - 7e-06 25.7 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1360 PF07098.11 EEB07208.1 - 0.012 15.5 0.4 0.057 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) ICMT PF04140.14 EEB07208.1 - 0.049 14.1 0.1 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2177 PF09945.9 EEB07208.1 - 1.6 8.8 5.3 0.54 10.4 1.3 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) MMR_HSR1_Xtn PF16897.5 EEB07209.1 - 3.5e-42 142.7 0.3 7e-42 141.8 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EEB07209.1 - 7.4e-23 80.4 0.0 1.3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EEB07209.1 - 1.3e-19 70.4 0.0 2.7e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB07209.1 - 5e-09 35.9 0.2 1.6e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEB07209.1 - 0.014 15.4 1.5 0.36 10.9 0.0 2.5 2 1 1 3 3 3 0 Dynamin family DUF2639 PF11121.8 EEB07209.1 - 0.024 14.6 0.2 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) MeaB PF03308.16 EEB07209.1 - 0.027 13.4 0.8 0.065 12.2 0.4 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EEB07209.1 - 0.36 10.7 1.7 5.9 6.8 0.3 2.8 2 1 1 3 3 3 0 RsgA GTPase Aldolase_II PF00596.21 EEB07210.2 - 5.3e-19 68.9 0.0 6.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HydF_dimer PF18128.1 EEB07210.2 - 0.12 12.5 0.0 0.41 10.7 0.0 1.9 1 1 1 2 2 2 0 Hydrogen maturase F dimerization domain ResIII PF04851.15 EEB07211.1 - 7.3e-22 78.2 0.0 2.1e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB07211.1 - 3.2e-21 75.7 0.1 2.8e-20 72.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB07211.1 - 9.3e-18 64.6 0.0 2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEB07211.1 - 0.013 15.2 0.1 0.043 13.5 0.0 1.9 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EEB07211.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 EEB07211.1 - 0.038 13.2 0.1 0.088 12.0 0.1 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Sec63 PF02889.16 EEB07212.1 - 9.5e-152 503.4 2.5 1.4e-86 289.8 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEB07212.1 - 3.4e-44 150.7 0.1 8.7e-28 97.3 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EEB07212.1 - 2.9e-33 114.4 0.2 9.6e-33 112.7 0.2 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EEB07212.1 - 1.9e-21 76.8 0.0 1.2e-14 54.6 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB07212.1 - 9.3e-10 38.8 0.0 9.1e-09 35.6 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEB07212.1 - 6.5e-07 29.2 0.0 0.1 12.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 EEB07212.1 - 7.4e-07 29.5 0.1 0.068 13.4 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EEB07212.1 - 0.023 14.5 0.4 2 8.1 0.0 3.3 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 EEB07212.1 - 0.12 11.9 0.0 12 5.2 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Acetyltransf_10 PF13673.7 EEB07213.1 - 8.2e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB07213.1 - 3.6e-11 43.3 0.0 4.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB07213.1 - 2.2e-09 37.6 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB07213.1 - 2.1e-07 31.1 0.0 0.00034 20.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB07213.1 - 3.6e-05 23.6 0.0 8.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EEB07213.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EEB07213.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltran PF12746.7 EEB07213.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase NPDC1 PF06809.11 EEB07213.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) G6PD_C PF02781.16 EEB07214.1 - 2.5e-105 351.8 0.0 3.9e-105 351.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EEB07214.1 - 5e-60 203.1 0.0 7.2e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 EEB07215.1 - 1.1e-16 61.1 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EEB07215.1 - 0.00054 20.0 8.7 0.0052 16.8 8.7 2.4 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 EEB07215.1 - 0.0028 17.5 0.0 0.062 13.1 0.0 2.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C3HC4_3 PF13920.6 EEB07216.1 - 6.5e-11 41.9 4.9 1.1e-10 41.2 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB07216.1 - 7.7e-09 35.3 7.0 7.7e-09 35.3 7.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB07216.1 - 3.8e-08 33.5 6.7 3.8e-08 33.5 6.7 1.8 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EEB07216.1 - 4.1e-08 32.9 7.0 7.3e-08 32.2 7.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EEB07216.1 - 5e-08 32.7 7.5 5e-08 32.7 7.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB07216.1 - 8.6e-08 32.0 6.5 1.8e-07 31.0 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEB07216.1 - 9.7e-06 25.5 3.0 9.7e-06 25.5 3.0 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEB07216.1 - 0.0012 18.8 1.0 0.0021 18.1 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEB07216.1 - 0.0017 18.6 5.3 0.0055 17.0 5.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEB07216.1 - 0.002 18.2 7.8 0.002 18.2 7.8 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EEB07216.1 - 0.015 15.1 5.9 0.03 14.1 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_13 PF17977.1 EEB07216.1 - 0.026 14.6 1.6 0.042 14.0 1.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EEB07216.1 - 0.03 14.2 2.5 0.056 13.3 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EEB07216.1 - 0.55 10.3 7.2 1.7 8.8 7.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 EEB07216.1 - 1.8 8.7 5.6 3.3 7.9 5.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EEB07216.1 - 5.5 6.8 12.3 0.4 10.5 5.5 2.6 3 0 0 3 3 3 0 RING-like zinc finger WD40 PF00400.32 EEB07217.2 - 5.1e-51 169.5 30.5 9.3e-07 29.5 0.1 11.7 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 EEB07217.2 - 7.1e-18 64.9 0.1 1.6e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EEB07217.2 - 1.4e-15 57.4 4.4 0.0052 17.1 0.0 9.0 3 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB07217.2 - 1.9e-08 33.7 5.2 0.032 13.2 0.4 6.1 3 3 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEB07217.2 - 0.00013 20.8 9.5 0.11 11.1 0.1 4.9 2 2 3 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EEB07217.2 - 0.0041 16.5 0.3 11 5.2 0.0 3.9 4 1 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 EEB07217.2 - 0.014 15.3 0.3 5.7 6.8 0.0 4.3 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A UTP15_C PF09384.10 EEB07217.2 - 0.069 12.8 2.1 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 UTP15 C terminal Thioredoxin PF00085.20 EEB07218.1 - 1.7e-33 114.7 0.1 2.2e-15 56.5 0.1 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EEB07218.1 - 4.9e-21 75.5 1.5 4.9e-07 29.8 0.2 3.9 2 1 2 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EEB07218.1 - 7e-10 38.7 2.4 2.9e-05 23.6 0.1 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EEB07218.1 - 1.7e-05 25.2 1.1 0.26 11.7 0.0 4.2 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EEB07218.1 - 0.00018 21.5 0.0 0.72 9.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin domain Calsequestrin PF01216.17 EEB07218.1 - 0.003 16.6 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Calsequestrin HyaE PF07449.11 EEB07218.1 - 0.0056 16.6 0.0 7.9 6.5 0.0 3.4 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EEB07218.1 - 0.065 13.6 2.8 9.9 6.6 0.0 4.3 4 1 1 5 5 5 0 Thioredoxin-like TraF PF13728.6 EEB07218.1 - 0.077 12.8 5.5 1.1 9.1 0.0 3.3 3 0 0 3 3 3 0 F plasmid transfer operon protein DIM1 PF02966.16 EEB07218.1 - 0.18 11.6 1.7 8.2 6.2 0.0 2.5 1 1 1 2 2 2 0 Mitosis protein DIM1 TrmE_N PF10396.9 EEB07219.1 - 3.5e-37 127.2 0.0 1e-36 125.8 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EEB07219.1 - 8e-36 124.1 3.4 1e-35 123.8 3.4 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EEB07219.1 - 1.7e-18 66.8 0.0 3.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEB07219.1 - 1.4e-07 31.7 0.1 1.6e-05 25.0 0.0 2.5 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EEB07219.1 - 6.9e-06 26.1 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EEB07219.1 - 0.00088 18.7 0.1 0.0056 16.0 0.0 2.1 1 1 1 2 2 2 1 AIG1 family FeoB_N PF02421.18 EEB07219.1 - 0.00098 18.7 0.0 0.0028 17.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 EEB07219.1 - 0.0047 17.4 0.2 0.029 14.9 0.0 2.4 2 1 0 2 2 2 1 ABC transporter Arf PF00025.21 EEB07219.1 - 0.0085 15.6 0.1 0.28 10.6 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB07219.1 - 0.019 14.5 0.1 0.54 9.8 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Rep-A_N PF04057.12 EEB07219.1 - 0.034 14.2 0.1 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain AAA_28 PF13521.6 EEB07219.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB07219.1 - 0.14 11.7 0.4 5.7 6.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain YL1_C PF08265.11 EEB07220.1 - 3.9e-16 58.5 0.4 1.2e-15 57.0 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Acyl-CoA_ox_N PF14749.6 EEB07220.1 - 0.12 13.0 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal LSM PF01423.22 EEB07221.1 - 1.7e-17 62.9 0.4 2.2e-17 62.5 0.4 1.2 1 0 0 1 1 1 1 LSM domain Aminotran_1_2 PF00155.21 EEB07222.1 - 9.5e-57 192.8 0.0 1.2e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEB07222.1 - 0.00017 20.6 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEB07222.1 - 0.002 17.5 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 EEB07222.1 - 0.014 14.1 0.1 0.047 12.4 0.0 1.8 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Glyoxalase_5 PF14696.6 EEB07222.1 - 0.055 13.6 0.2 0.91 9.7 0.1 2.7 2 1 1 3 3 3 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DegT_DnrJ_EryC1 PF01041.17 EEB07222.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DMA PF03474.14 EEB07222.1 - 0.2 11.3 0.3 24 4.7 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif GCV_T PF01571.21 EEB07223.2 - 0.0019 17.6 0.0 0.0044 16.4 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain IF-2B PF01008.17 EEB07224.1 - 2.6e-85 286.1 0.0 3.5e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pro_isomerase PF00160.21 EEB07225.1 - 6.7e-50 169.4 0.2 1.7e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EEB07225.1 - 0.00013 21.5 4.6 0.00019 20.9 1.1 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger IHABP4_N PF16174.5 EEB07225.1 - 0.31 11.6 6.5 0.27 11.8 0.7 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Acetyltransf_1 PF00583.25 EEB07226.1 - 1.3e-10 41.6 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB07226.1 - 1.3e-07 32.0 0.2 6.4e-07 29.7 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEB07226.1 - 1.7e-06 28.0 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB07226.1 - 9.3e-05 22.3 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EEB07226.1 - 0.00014 22.6 0.0 0.00017 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEB07226.1 - 0.00017 21.7 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEB07226.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase bZIP_1 PF00170.21 EEB07227.1 - 2.7e-08 33.8 10.4 2.7e-08 33.8 10.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EEB07227.1 - 0.00015 21.8 9.5 0.00015 21.8 9.5 3.5 3 0 0 3 3 3 1 Basic region leucine zipper Dala_Dala_lig_N PF01820.21 EEB07227.1 - 0.28 11.7 1.8 1 9.8 1.8 2.3 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus Kinesin_assoc PF16183.5 EEB07227.1 - 1.6 8.8 10.4 2 8.6 0.1 2.4 1 1 0 2 2 2 0 Kinesin-associated Ribosomal_L2_C PF03947.18 EEB07228.1 - 9e-42 142.2 3.8 2e-41 141.1 3.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEB07228.1 - 9e-15 54.4 0.1 2.4e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain 2-Hacid_dh_C PF02826.19 EEB07229.1 - 3e-48 163.5 0.0 4.8e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEB07229.1 - 3.7e-41 139.9 0.0 5.2e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEB07229.1 - 0.00012 22.3 0.0 0.00037 20.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EEB07229.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EEB07229.1 - 0.021 14.6 0.0 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 ACT domain NAP PF00956.18 EEB07230.1 - 4.3e-86 288.4 7.9 6.8e-86 287.8 7.9 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RisS_PPD PF16524.5 EEB07230.1 - 0.053 13.8 0.1 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS CAF1A PF12253.8 EEB07230.1 - 3.3 8.0 19.9 0.51 10.5 0.2 3.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A DUF4846 PF16138.5 EEB07231.1 - 0.037 13.5 0.3 0.19 11.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (4846) CASP_C PF08172.12 EEB07232.1 - 6.7e-41 140.3 13.2 6.7e-41 140.3 13.2 5.3 3 2 1 4 4 4 1 CASP C terminal Filament PF00038.21 EEB07232.1 - 0.0058 16.3 18.7 0.0058 16.3 18.7 4.2 3 1 1 4 4 4 2 Intermediate filament protein CtIP_N PF10482.9 EEB07232.1 - 0.017 15.2 1.6 0.017 15.2 1.6 5.5 3 1 2 6 6 6 0 Tumour-suppressor protein CtIP N-terminal domain KASH_CCD PF14662.6 EEB07232.1 - 0.019 14.8 1.7 0.019 14.8 1.7 5.5 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 EEB07232.1 - 0.021 14.9 3.0 0.021 14.9 3.0 8.1 5 2 1 7 7 7 0 TolA binding protein trimerisation GAS PF13851.6 EEB07232.1 - 0.051 12.9 87.3 0.49 9.7 3.2 6.2 3 1 3 6 6 6 0 Growth-arrest specific micro-tubule binding DUF2853 PF11015.8 EEB07232.1 - 0.76 10.5 11.5 0.15 12.7 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2853) DUF4200 PF13863.6 EEB07232.1 - 2.8 8.4 87.1 0.047 14.1 17.6 5.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4200) Es2 PF09751.9 EEB07233.1 - 1.7e-14 54.5 11.2 7.3e-06 26.0 0.0 3.8 1 1 2 3 3 3 3 Nuclear protein Es2 Cas_Csy4 PF09618.10 EEB07234.1 - 0.14 12.3 3.2 0.24 11.5 3.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) CDC45 PF02724.14 EEB07234.1 - 0.2 9.9 4.6 0.28 9.4 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BRE1 PF08647.11 EEB07235.1 - 2.2e-14 53.3 7.8 2.2e-14 53.3 7.8 6.2 6 2 1 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 EEB07235.1 - 5.2e-08 32.6 7.1 1.1e-07 31.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB07235.1 - 4.9e-06 26.3 8.3 1.4e-05 24.8 8.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEB07235.1 - 9.6e-06 25.4 10.8 2.1e-05 24.3 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB07235.1 - 1.4e-05 25.3 11.8 4.4e-05 23.7 11.8 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EEB07235.1 - 2.8e-05 23.9 5.8 5.3e-05 23.0 5.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEB07235.1 - 0.00021 21.3 7.7 0.00068 19.6 7.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEB07235.1 - 0.0004 20.3 12.0 0.00099 19.0 12.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEB07235.1 - 0.00043 20.5 7.3 0.0016 18.7 7.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEB07235.1 - 0.12 12.4 3.7 0.24 11.5 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EEB07235.1 - 0.97 9.3 9.6 0.06 13.1 4.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EEB07235.1 - 1 9.6 11.5 0.53 10.5 7.4 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EEB07235.1 - 2.6 8.0 10.0 2.6 7.9 0.0 4.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Sec8_exocyst PF04048.14 EEB07236.1 - 5.4e-28 97.7 3.4 5.4e-28 97.7 3.4 2.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EEB07236.1 - 5.5e-06 25.9 5.7 5.5e-06 25.9 5.7 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex HTH_46 PF15977.5 EEB07236.1 - 0.086 12.9 0.2 0.31 11.1 0.2 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding ParcG PF10274.9 EEB07236.1 - 0.34 11.0 3.8 0.46 10.6 0.1 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein ZnuA PF01297.17 EEB07236.1 - 0.43 9.9 4.1 0.13 11.7 0.4 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic IPK PF03770.16 EEB07237.1 - 4.2e-55 186.7 0.0 8.2e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase RSN1_7TM PF02714.15 EEB07238.1 - 7.7e-63 212.4 23.0 1.5e-62 211.4 23.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEB07238.1 - 1.7e-32 112.4 0.8 1.7e-32 112.4 0.8 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEB07238.1 - 1.5e-27 97.0 0.2 2.4e-27 96.3 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Oxysterol_BP PF01237.18 EEB07239.2 - 1.6e-63 214.8 2.8 3.6e-54 184.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Ribosomal_S16 PF00886.19 EEB07240.1 - 3.5e-22 78.2 0.0 4.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 HLH PF00010.26 EEB07241.1 - 4.8e-16 58.4 0.0 8.5e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 EEB07241.1 - 7.4 6.7 21.8 1.3 9.2 9.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Hydrolase_like PF13242.6 EEB07243.1 - 2.3e-24 85.2 0.0 6e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEB07243.1 - 3.3e-24 84.9 0.0 1.5e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB07243.1 - 0.012 15.9 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB07243.1 - 0.016 15.3 0.0 0.08 13.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 EEB07244.1 - 2.8e-45 151.4 11.0 4.6e-11 43.1 0.6 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07244.1 - 1.6e-18 66.8 0.5 0.00016 21.9 0.2 5.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB07244.1 - 9.5e-12 44.3 11.4 0.0019 17.0 0.0 6.1 2 1 4 7 7 7 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEB07244.1 - 1.6e-06 27.4 1.1 0.034 13.1 0.0 4.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEB07244.1 - 0.00012 20.9 1.2 0.28 9.9 0.0 3.6 2 1 1 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 EEB07244.1 - 0.0044 16.4 1.2 0.57 9.5 0.0 2.8 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EEB07244.1 - 0.021 14.2 0.0 0.066 12.5 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain IKI3 PF04762.12 EEB07244.1 - 0.058 11.4 0.2 0.41 8.6 0.0 2.1 2 1 0 2 2 2 0 IKI3 family SecY PF00344.20 EEB07245.1 - 1.3e-66 225.0 7.3 1.7e-66 224.6 7.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EEB07245.1 - 6.5e-17 61.1 0.2 2.7e-16 59.1 0.3 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p MMR_HSR1_Xtn PF16897.5 EEB07246.1 - 5.6e-43 145.3 1.3 1.1e-42 144.3 1.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EEB07246.1 - 5.8e-22 77.9 0.1 1e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EEB07246.1 - 7.8e-22 77.1 0.0 2.3e-21 75.6 0.0 1.9 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EEB07246.1 - 5.8e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEB07246.1 - 2e-05 24.7 0.6 0.0082 16.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EEB07246.1 - 0.0031 16.8 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SNF2_N PF00176.23 EEB07246.1 - 0.092 11.5 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain VWA_2 PF13519.6 EEB07246.1 - 0.15 12.7 0.1 0.45 11.2 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_28 PF13521.6 EEB07246.1 - 0.17 12.1 0.2 0.34 11.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain Cut12 PF11500.8 EEB07247.1 - 1e-12 48.2 5.2 3.7e-12 46.4 5.1 2.3 1 1 0 1 1 1 1 Spindle pole body formation-associated protein Staph_haemo PF05480.11 EEB07247.1 - 0.006 16.3 0.2 0.91 9.3 0.0 3.2 3 0 0 3 3 3 1 Staphylococcus haemolytic protein CAAX_1 PF15895.5 EEB07247.1 - 0.043 13.7 0.2 0.083 12.8 0.2 1.4 1 0 0 1 1 1 0 CAAX box cerebral protein 1 DUF1283 PF06932.11 EEB07247.1 - 0.3 11.3 4.7 1.2 9.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) CYSTM PF12734.7 EEB07248.1 - 2.5e-11 43.7 18.3 2.5e-11 43.7 18.3 3.4 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EEB07248.1 - 0.1 13.3 2.3 0.12 13.1 2.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 EEB07248.1 - 7.3 6.6 9.5 7.9 6.4 9.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) XPA_C PF05181.12 EEB07249.1 - 2.5e-23 81.8 1.3 2.5e-23 81.8 1.3 2.1 3 0 0 3 3 3 1 XPA protein C-terminus XPA_N PF01286.18 EEB07249.1 - 9.4e-11 41.6 7.0 1.7e-10 40.7 7.0 1.5 1 0 0 1 1 1 1 XPA protein N-terminal NEMP PF10225.9 EEB07249.1 - 6.1 6.4 5.7 6.9 6.3 4.5 1.6 1 1 1 2 2 2 0 NEMP family Ribosomal_S19e PF01090.19 EEB07250.1 - 9.6e-60 200.2 0.1 1.1e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Kinesin PF00225.23 EEB07251.1 - 2.8e-113 378.2 0.0 4.5e-113 377.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEB07251.1 - 1.4e-23 83.5 0.0 3.3e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Mad3_BUB1_I PF08311.12 EEB07251.1 - 0.038 14.0 0.4 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 FAM194 PF14977.6 EEB07251.1 - 0.066 12.5 1.5 0.12 11.6 1.5 1.3 1 0 0 1 1 1 0 FAM194 protein FAM76 PF16046.5 EEB07251.1 - 0.11 11.8 2.4 0.26 10.6 2.4 1.6 1 0 0 1 1 1 0 FAM76 protein Helicase_IV_N PF12462.8 EEB07251.1 - 0.44 10.5 2.7 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal VID27 PF08553.10 EEB07252.2 - 2.2e-180 599.3 0.2 2.9e-180 598.9 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EEB07252.2 - 4.5e-58 195.9 1.7 4.5e-58 195.9 1.7 3.4 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 EEB07252.2 - 2.7e-43 146.7 6.4 6.7e-43 145.4 2.8 3.1 3 0 0 3 3 3 1 VID27 PH-like domain MARVEL PF01284.23 EEB07253.1 - 1.5e-21 77.0 10.6 1.9e-21 76.6 10.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Zip PF02535.22 EEB07253.1 - 4.3 6.5 5.7 5.1 6.2 5.5 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter NACHT PF05729.12 EEB07254.1 - 0.0016 18.4 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 NACHT domain Rad51 PF08423.11 EEB07254.1 - 0.0089 15.3 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 EEB07254.1 - 0.009 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain HCV_NS4a PF01006.20 EEB07254.1 - 0.01 15.6 0.1 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a AAA_25 PF13481.6 EEB07254.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain OS-D PF03392.13 EEB07254.1 - 0.044 13.9 1.2 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D SRPRB PF09439.10 EEB07254.1 - 0.089 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S27e PF01667.17 EEB07255.1 - 8.6e-29 99.0 5.7 1.1e-28 98.7 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EEB07255.1 - 0.063 12.8 3.0 0.093 12.3 3.0 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Prok-RING_1 PF14446.6 EEB07255.1 - 0.29 11.1 3.6 0.51 10.3 3.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Mu-like_Com PF10122.9 EEB07255.1 - 0.75 9.3 3.8 5.8 6.4 0.4 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com Peptidase_C12 PF01088.21 EEB07256.1 - 5.4e-62 209.3 0.0 8.1e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EEB07256.1 - 2.1e-13 49.9 0.5 4.7e-13 48.8 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Pkinase PF00069.25 EEB07257.1 - 1.4e-59 201.6 0.0 1.8e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07257.1 - 1.6e-36 125.9 0.0 2.3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07257.1 - 9e-07 28.5 0.0 2.1e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEB07257.1 - 0.00053 19.0 0.0 0.00093 18.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EEB07257.1 - 0.0083 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EEB07257.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MFS_1 PF07690.16 EEB07258.2 - 6e-38 130.7 29.6 6e-38 130.7 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07258.2 - 3.1e-07 29.6 20.6 4.4e-06 25.8 20.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3464 PF11947.8 EEB07258.2 - 0.03 14.1 0.7 3.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Mito_carr PF00153.27 EEB07259.2 - 9.3e-44 147.3 2.6 1.8e-14 53.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MIS13 PF08202.11 EEB07260.1 - 5e-57 193.5 8.2 8.3e-57 192.8 8.2 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FlgO PF17680.1 EEB07260.1 - 0.015 15.0 1.2 0.04 13.6 1.2 1.7 1 0 0 1 1 1 0 FlgO protein DUF2547 PF10818.8 EEB07260.1 - 0.89 10.5 4.6 0.43 11.6 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2547) zf-UBR PF02207.20 EEB07261.1 - 3e-12 46.5 14.3 3e-12 46.5 14.3 3.3 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 EEB07261.1 - 0.00027 20.8 8.9 0.00027 20.8 8.9 3.3 3 0 0 3 3 3 1 PHD-finger MCM PF00493.23 EEB07262.1 - 5.5e-100 333.1 0.1 8.3e-100 332.5 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEB07262.1 - 5.4e-37 126.4 0.0 9.2e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EEB07262.1 - 6e-36 124.0 20.7 6e-36 124.0 20.7 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EEB07262.1 - 5.3e-28 97.3 0.8 1.2e-27 96.1 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEB07262.1 - 6.3e-13 49.2 0.2 2.7e-12 47.2 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEB07262.1 - 1.1e-08 34.7 0.0 3.3e-07 29.9 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEB07262.1 - 1.4e-06 28.4 0.0 3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEB07262.1 - 0.00055 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB07262.1 - 0.003 17.3 0.1 0.017 14.9 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EEB07262.1 - 0.076 13.4 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEB07262.1 - 0.11 12.3 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sec23_trunk PF04811.15 EEB07263.1 - 4.1e-67 226.3 0.0 1.8e-66 224.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEB07263.1 - 4.3e-19 69.0 0.1 7.9e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEB07263.1 - 8.3e-18 64.1 0.0 1.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EEB07263.1 - 2e-15 56.5 5.1 3.6e-15 55.7 5.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEB07263.1 - 1.8e-05 24.5 0.0 5.6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat HAD_SAK_1 PF10307.9 EEB07264.1 - 1.5e-56 191.5 0.0 2.1e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Fig1 PF12351.8 EEB07265.1 - 1.5e-05 25.0 19.4 0.00058 19.8 14.1 3.0 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SepZ PF06066.11 EEB07265.1 - 1.2 9.4 3.3 2.1 8.6 1.7 2.2 2 1 0 2 2 2 0 SepZ DUF4064 PF13273.6 EEB07265.1 - 6.5 7.1 12.3 1.1 9.5 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) WD40 PF00400.32 EEB07266.2 - 5.7e-23 80.8 16.4 0.00062 20.5 0.2 12.2 12 0 0 12 12 12 5 WD domain, G-beta repeat Nup160 PF11715.8 EEB07266.2 - 7.9e-05 21.5 5.3 0.069 11.8 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEB07266.2 - 0.024 13.4 2.0 1 8.0 0.1 3.7 2 2 1 3 3 3 0 Nup133 N terminal like GTP_EFTU PF00009.27 EEB07267.1 - 7.4e-61 205.1 0.1 1.2e-60 204.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEB07267.1 - 2.9e-32 111.0 0.0 6.1e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EEB07267.1 - 4.3e-30 103.6 0.0 9.8e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEB07267.1 - 9.3e-23 80.1 0.0 2.7e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB07267.1 - 2e-13 50.5 0.1 1.3e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EEB07267.1 - 8.4e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 EEB07267.1 - 0.023 15.2 0.0 0.76 10.3 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 EEB07267.1 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sec66 PF09802.9 EEB07268.1 - 2.4e-61 206.5 0.1 2.8e-61 206.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Insulin_TMD PF17870.1 EEB07268.1 - 0.1 12.7 2.0 0.18 11.9 2.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 3Beta_HSD PF01073.19 EEB07268.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAPS_reduct PF01507.19 EEB07268.1 - 0.18 11.8 1.2 0.26 11.3 1.2 1.1 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family THOC7 PF05615.13 EEB07268.1 - 0.44 10.8 7.1 0.6 10.4 7.1 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Tom37 PF10568.9 EEB07269.1 - 1.9e-27 96.1 0.0 3.4e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EEB07269.1 - 1.6e-07 31.0 0.0 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EEB07269.1 - 1.9e-07 31.8 0.0 4.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EEB07269.1 - 2.6e-05 24.3 0.1 0.019 15.1 0.0 3.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB07269.1 - 6.9e-05 22.8 0.1 0.00063 19.7 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain PAP2 PF01569.21 EEB07270.2 - 3.6e-26 91.5 0.3 8.5e-26 90.3 0.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily EamA PF00892.20 EEB07270.2 - 7.2 6.8 10.5 12 6.0 0.7 3.2 3 0 0 3 3 3 0 EamA-like transporter family DUF1769 PF08588.10 EEB07271.2 - 5.6e-21 74.5 0.3 1.1e-20 73.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) WGG PF10273.9 EEB07272.1 - 8.7e-29 100.0 1.6 1.8e-28 99.0 1.6 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EEB07272.1 - 0.017 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ribosomal_S17 PF00366.20 EEB07273.1 - 3.6e-22 78.2 2.6 4.1e-22 78.1 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 EutN_CcmL PF03319.13 EEB07273.1 - 0.03 14.9 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome HD_3 PF13023.6 EEB07273.1 - 0.083 12.8 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 HD domain Mucin_bdg PF03272.13 EEB07273.1 - 0.089 12.8 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module DMRL_synthase PF00885.19 EEB07274.1 - 6.9e-53 178.3 0.0 7.7e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Stn1 PF10451.9 EEB07276.1 - 1.1e-10 41.0 0.1 1.7e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 SAICAR_synt PF01259.18 EEB07277.1 - 4.9e-101 337.6 0.0 6e-101 337.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MHC_I_3 PF16497.5 EEB07278.1 - 0.0012 18.4 0.5 0.0016 17.9 0.5 1.2 1 0 0 1 1 1 1 MHC-I family domain Ras PF00071.22 EEB07279.1 - 4.2e-56 189.0 0.0 4.8e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB07279.1 - 8.7e-23 80.8 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB07279.1 - 1.8e-10 40.5 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEB07279.1 - 0.0011 19.1 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEB07279.1 - 0.0022 17.4 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EEB07279.1 - 0.0033 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EEB07279.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EEB07279.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EEB07279.1 - 0.13 11.4 0.0 0.35 10.0 0.0 1.4 1 1 1 2 2 2 0 G-protein alpha subunit dsDNA_bind PF01984.20 EEB07280.1 - 1.5e-33 115.4 15.2 1.8e-33 115.2 15.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UvrA_inter PF17760.1 EEB07280.1 - 6.5e-05 23.0 0.9 0.00011 22.2 0.9 1.3 1 0 0 1 1 1 1 UvrA interaction domain Arteri_nucleo PF01481.16 EEB07280.1 - 0.035 14.4 1.2 0.035 14.4 1.2 1.7 1 1 1 2 2 2 0 Arterivirus nucleocapsid protein Sec2p PF06428.11 EEB07281.1 - 3.6e-27 94.1 6.7 3.6e-27 94.1 6.7 2.2 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Laminin_II PF06009.12 EEB07281.1 - 0.18 11.8 6.4 0.22 11.5 1.9 2.3 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 EEB07281.1 - 0.27 10.1 13.4 0.43 9.4 13.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EEB07281.1 - 0.47 7.9 16.9 0.6 7.5 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FapA PF03961.13 EEB07281.1 - 0.87 8.1 8.4 0.91 8.1 7.5 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EEB07281.1 - 1.9 8.6 16.1 4.1 7.5 16.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 EEB07281.1 - 3.7 5.3 11.9 0.41 8.5 5.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DivIVA PF05103.13 EEB07281.1 - 4.6 7.3 12.0 15 5.7 12.0 1.8 1 1 0 1 1 1 0 DivIVA protein PRKG1_interact PF15898.5 EEB07281.1 - 5.7 7.9 17.1 6.7e+02 1.3 17.1 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain T3SSipB PF16535.5 EEB07281.1 - 8.8 6.8 12.2 24 5.3 5.1 2.6 1 1 1 2 2 2 0 Type III cell invasion protein SipB GCN5L1 PF06320.13 EEB07281.1 - 9.1 6.5 10.6 1.6 8.9 4.5 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Enolase_C PF00113.22 EEB07282.2 - 4.8e-226 748.3 2.4 5.1e-121 403.5 0.1 2.1 1 1 1 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EEB07282.2 - 3.2e-58 195.6 0.3 6.9e-58 194.5 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EEB07282.2 - 1.2e-18 67.5 0.0 5.1e-08 32.8 0.0 2.5 1 1 1 2 2 2 2 Enolase C-terminal domain-like MAAL_C PF07476.11 EEB07282.2 - 9.2e-07 28.3 0.5 0.026 13.7 0.1 2.4 2 0 0 2 2 2 2 Methylaspartate ammonia-lyase C-terminus INTAP PF16617.5 EEB07282.2 - 0.0013 19.0 0.3 3 8.2 0.0 2.5 2 0 0 2 2 2 2 Intersectin and clathrin adaptor AP2 binding region DUF1533 PF07550.11 EEB07282.2 - 0.0024 17.7 1.3 3.2 7.7 0.1 3.1 2 2 0 2 2 2 2 Protein of unknown function (DUF1533) DUF5475 PF17569.2 EEB07282.2 - 0.045 14.1 2.8 44 4.5 0.2 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5475) ANAPC5 PF12862.7 EEB07282.2 - 0.054 13.6 0.0 8.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 PAP_assoc PF03828.19 EEB07283.1 - 2.4e-16 59.7 0.0 4.8e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEB07283.1 - 3.2e-08 33.8 0.0 6.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEB07283.1 - 0.0085 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase HECT PF00632.25 EEB07284.1 - 5e-96 321.8 0.1 1.1e-95 320.7 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 EEB07284.1 - 5.2e-76 256.0 16.4 1.5e-75 254.5 0.2 4.4 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EEB07284.1 - 2.3e-46 158.9 9.9 2.2e-24 86.5 5.9 3.4 2 1 1 3 3 3 2 Domain of Unknown Function (DUF908) UBM PF14377.6 EEB07284.1 - 5.9e-08 31.9 14.7 1.4e-06 27.6 0.2 3.9 4 0 0 4 4 4 2 Ubiquitin binding region DUF5584 PF17822.1 EEB07284.1 - 0.17 11.4 2.6 7 6.0 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5584) S4 PF01479.25 EEB07285.1 - 9.7e-13 47.6 0.1 2e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EEB07285.1 - 8.7e-09 36.2 0.8 1.7e-08 35.3 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Churchill PF06573.11 EEB07285.1 - 0.024 14.9 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 Churchill protein Ctf8 PF09696.10 EEB07286.1 - 1.4e-09 38.4 0.5 4.7e-09 36.7 0.5 1.7 1 1 1 2 2 2 1 Ctf8 GXGXG PF01493.19 EEB07286.1 - 0.04 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 GXGXG motif RAI1 PF08652.11 EEB07287.1 - 2.1e-25 88.7 0.1 4.7e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease eIF-3_zeta PF05091.12 EEB07287.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Oxysterol_BP PF01237.18 EEB07288.1 - 2.3e-47 161.6 0.2 7.6e-25 87.5 0.0 3.1 2 1 1 3 3 3 3 Oxysterol-binding protein eIF3_N PF09440.10 EEB07289.2 - 1.2e-50 171.4 5.2 1.2e-50 171.4 5.2 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EEB07289.2 - 0.0003 21.3 0.4 0.0011 19.4 0.4 2.0 1 0 0 1 1 1 1 PCI domain Ribosomal_60s PF00428.19 EEB07289.2 - 0.0067 17.0 3.4 0.0067 17.0 3.4 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein FeoC PF09012.10 EEB07289.2 - 0.18 11.9 0.3 0.89 9.7 0.1 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator Nop PF01798.18 EEB07290.1 - 1.1e-88 296.6 0.1 1.1e-88 296.6 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEB07290.1 - 2.1e-21 76.0 0.4 2.1e-21 76.0 0.4 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Cpn60_TCP1 PF00118.24 EEB07291.1 - 1.7e-162 541.5 1.4 1.9e-162 541.3 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RasGAP PF00616.19 EEB07292.2 - 2.3e-50 171.2 0.0 4.6e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EEB07292.2 - 1.7e-25 89.7 2.1 1.7e-25 89.7 2.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus TLE_N PF03920.15 EEB07292.2 - 0.14 12.2 1.7 8.3 6.5 0.1 3.3 3 1 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain YabA PF06156.13 EEB07292.2 - 0.2 12.3 5.2 6.4 7.5 0.2 3.2 3 0 0 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 EEB07292.2 - 2 8.8 6.1 22 5.5 0.6 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CBS PF00571.28 EEB07293.1 - 1.7e-21 76.4 2.4 1.3e-08 35.2 0.0 4.4 4 0 0 4 4 4 4 CBS domain zf-RanBP PF00641.18 EEB07294.1 - 2.9e-18 64.9 24.3 1.1e-08 34.2 2.3 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EEB07294.1 - 2.3e-08 33.7 0.0 5.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) rRNA_proc-arch PF13234.6 EEB07295.1 - 1.5e-68 231.7 1.1 2.8e-68 230.8 1.1 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EEB07295.1 - 2.1e-49 167.3 0.1 4.3e-49 166.3 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EEB07295.1 - 5.4e-19 68.6 0.0 9.5e-18 64.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07295.1 - 9.5e-07 29.1 0.0 6.2e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07295.1 - 3.6e-06 27.1 0.0 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEB07295.1 - 0.0026 18.0 0.0 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EEB07295.1 - 0.012 15.6 0.1 0.09 12.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EEB07295.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EEB07295.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NTP_transf_2 PF01909.23 EEB07296.1 - 1.3e-08 35.0 0.3 5.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EEB07296.1 - 1.9e-07 31.2 0.1 7.1e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase Nrap_D2 PF17403.2 EEB07296.1 - 1.1e-05 25.2 0.6 0.00016 21.5 0.6 2.4 1 1 0 1 1 1 1 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 EEB07296.1 - 1.4e-05 25.1 0.0 6.4e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase tRNA_NucTransf2 PF09249.11 EEB07296.1 - 0.0069 16.6 0.0 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain PAP_central PF04928.17 EEB07296.1 - 0.0077 15.2 1.4 0.71 8.8 0.1 3.1 3 0 0 3 3 3 1 Poly(A) polymerase central domain MarR PF01047.22 EEB07296.1 - 0.023 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 MarR family PadR PF03551.14 EEB07296.1 - 0.037 14.0 0.1 0.16 12.0 0.1 2.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PG_binding_3 PF09374.10 EEB07296.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain MdcG PF10620.9 EEB07296.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Dynamin_M PF01031.20 EEB07297.2 - 5.7e-103 344.1 0.6 1.3e-102 342.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EEB07297.2 - 8.4e-57 191.9 0.0 1.8e-56 190.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EEB07297.2 - 6.9e-30 103.1 3.7 1.8e-29 101.7 3.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEB07297.2 - 5.4e-05 23.3 0.1 0.00021 21.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SANT_DAMP1_like PF16282.5 EEB07298.2 - 3.3e-28 97.7 4.0 6.4e-28 96.8 4.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EEB07298.2 - 5.7e-10 39.3 0.6 2.1e-09 37.5 0.6 1.9 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DMAP1_like PF17024.5 EEB07298.2 - 0.0055 16.8 0.0 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Putative DMAP1-like Myb_DNA-binding PF00249.31 EEB07298.2 - 0.089 13.0 1.7 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain GCD14 PF08704.10 EEB07299.1 - 1.2e-94 316.6 0.0 1.5e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EEB07299.1 - 4.8e-05 23.2 0.0 7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EEB07299.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 EEB07299.1 - 0.026 14.3 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 EEB07299.1 - 0.035 13.2 0.0 0.093 11.8 0.0 1.6 2 0 0 2 2 2 0 Fibrillarin DUF3128 PF11326.8 EEB07300.2 - 4.4e-21 75.0 4.3 6.7e-21 74.5 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) IFP_35_N PF07334.13 EEB07300.2 - 0.027 14.6 0.2 5.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Blt1_C PF17183.4 EEB07300.2 - 0.082 12.5 1.3 0.19 11.4 1.3 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain NRN1 PF15056.6 EEB07300.2 - 0.1 12.7 1.5 0.19 11.8 1.4 1.7 1 1 0 1 1 1 0 Neuritin protein family UPF0203 PF05254.12 EEB07300.2 - 2.3 8.5 7.7 5.2 7.4 7.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) AlaDh_PNT_N PF05222.15 EEB07301.1 - 8.5e-30 103.8 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EEB07301.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NIF PF03031.18 EEB07302.1 - 2.4e-52 176.8 0.0 3.2e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EEB07302.1 - 0.045 14.1 0.3 1.1 9.6 0.0 2.7 1 1 2 3 3 3 0 haloacid dehalogenase-like hydrolase eIF-5_eIF-2B PF01873.17 EEB07303.1 - 5.2e-40 136.0 0.0 9.2e-40 135.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EEB07303.1 - 5.5e-20 71.3 0.3 5.5e-20 71.3 0.3 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1754 PF08555.10 EEB07303.1 - 0.02 15.7 0.5 0.02 15.7 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RNA_POL_M_15KD PF02150.16 EEB07303.1 - 0.079 12.8 2.0 0.25 11.2 2.0 1.9 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Med1 PF10744.9 EEB07304.2 - 4.2e-29 101.8 0.4 7.3e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 EEB07305.1 - 4.8e-51 173.7 0.0 8.7e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07305.1 - 5e-16 58.8 0.0 1.7e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEB07305.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELL PF10390.9 EEB07306.1 - 1.9e-11 44.0 0.0 1.9e-11 44.0 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL TFIIA PF03153.13 EEB07306.1 - 0.47 10.4 22.1 0.11 12.5 17.9 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ORC4_C PF14629.6 EEB07307.1 - 2.1e-42 144.9 0.1 5.6e-42 143.6 0.1 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EEB07307.1 - 9.3e-12 45.6 0.2 3e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 AAA ATPase domain AT_hook PF02178.19 EEB07307.1 - 3.2e-06 26.4 53.2 0.074 13.0 1.4 5.7 5 0 0 5 5 5 5 AT hook motif AAA_22 PF13401.6 EEB07307.1 - 0.00023 21.4 0.0 0.00071 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEB07307.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EEB07307.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EEB07307.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA12 PF10443.9 EEB07307.1 - 0.068 11.9 0.0 0.068 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein AAA_14 PF13173.6 EEB07307.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L12_N PF16320.5 EEB07307.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain NAD_binding_1 PF00175.21 EEB07308.1 - 3.9e-18 66.1 0.0 6.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEB07308.1 - 4.3e-18 65.5 0.0 7.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEB07308.1 - 0.00038 20.6 0.0 0.0006 20.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain TatC PF00902.18 EEB07308.1 - 0.093 12.5 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) FRG1 PF06229.12 EEB07309.2 - 7.9e-18 64.9 0.2 1.7e-17 63.8 0.2 1.5 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EEB07309.2 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.6 1 1 0 1 1 1 1 Fascin domain Peptidase_M16 PF00675.20 EEB07310.1 - 3.4e-49 166.6 3.1 4.1e-49 166.4 1.3 2.1 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEB07310.1 - 8.7e-39 133.4 0.0 1.9e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain CybS PF05328.12 EEB07311.1 - 2.8e-44 150.0 0.0 3.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PIG-P PF08510.12 EEB07311.1 - 0.001 19.0 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EEB07311.1 - 0.0022 18.3 0.1 0.004 17.4 0.1 1.5 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) E1-E2_ATPase PF00122.20 EEB07312.1 - 6.6e-47 159.4 0.1 6.6e-47 159.4 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEB07312.1 - 4.6e-37 128.3 0.1 7e-37 127.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EEB07312.1 - 7.7e-11 42.3 0.2 8.7e-09 35.7 0.0 3.0 3 0 0 3 3 3 1 Heavy-metal-associated domain PRA-CH PF01502.18 EEB07313.1 - 6.2e-24 83.6 0.6 1.2e-23 82.7 0.6 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EEB07313.1 - 7.1e-17 61.6 0.1 1.5e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EEB07313.1 - 0.0027 17.9 0.3 0.054 13.7 0.0 2.4 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 EEB07313.1 - 0.025 14.8 0.4 0.097 12.9 0.1 2.2 2 0 0 2 2 2 0 MazG-like family Amino_oxidase PF01593.24 EEB07314.2 - 2.7e-32 112.6 0.4 8e-32 111.1 0.0 2.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EEB07314.2 - 1.1e-10 41.7 0.0 3.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EEB07314.2 - 5.8e-08 32.8 0.0 3e-07 30.6 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EEB07314.2 - 9.1e-06 26.0 1.4 9.1e-06 26.0 1.4 2.9 3 0 0 3 3 3 1 HMG (high mobility group) box DAO PF01266.24 EEB07314.2 - 1.3e-05 25.0 0.0 0.00057 19.6 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEB07314.2 - 0.001 18.4 0.1 0.052 12.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB07314.2 - 0.0012 18.8 0.3 2.7 8.0 0.0 3.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding RskA PF10099.9 EEB07314.2 - 7.5 6.8 36.9 0.25 11.6 8.9 2.8 1 1 0 2 2 2 0 Anti-sigma-K factor rskA Cyclin_N PF00134.23 EEB07317.1 - 1e-37 128.7 1.2 1.9e-37 127.9 1.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB07317.1 - 1.7e-06 28.1 0.0 3.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Acid_PPase PF12689.7 EEB07318.2 - 9.6e-56 188.3 0.0 1.1e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 EEB07318.2 - 0.048 13.4 0.4 0.27 11.0 0.4 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EEB07318.2 - 0.086 13.1 0.0 1.4 9.2 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 EEB07319.1 - 3.5e-08 33.4 10.4 8.2e-08 32.2 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEB07319.1 - 1.3e-06 27.7 1.4 2.7e-06 26.6 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Chorismate_bind PF00425.18 EEB07322.1 - 3.7e-74 249.5 0.0 5.3e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EEB07322.1 - 5.7e-33 114.3 0.0 9.2e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EEB07322.1 - 6.5e-15 55.6 0.0 1.6e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EEB07322.1 - 9.3e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Carb_kinase PF01256.17 EEB07322.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Stc1 PF12898.7 EEB07323.1 - 1.3e-15 57.7 11.8 1.3e-15 57.7 11.8 2.2 2 1 0 2 2 2 1 Stc1 domain DUF3295 PF11702.8 EEB07323.1 - 0.26 10.6 13.3 0.35 10.2 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF3947 PF13135.6 EEB07323.1 - 1.7 8.9 6.2 2.9 8.2 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) PHD PF00628.29 EEB07323.1 - 4.5 7.2 11.1 9.1 6.3 2.2 3.3 3 0 0 3 3 3 0 PHD-finger zf-C6H2 PF15801.5 EEB07323.1 - 6.4 7.2 10.0 15 6.0 2.1 2.7 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding HECT PF00632.25 EEB07324.2 - 9.5e-46 156.7 0.2 5.9e-45 154.1 0.0 2.5 3 1 1 4 4 4 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.12 EEB07324.2 - 0.65 9.9 12.0 6.3 6.7 10.3 2.4 2 0 0 2 2 2 0 LSD1 zinc finger AIM3 PF17096.5 EEB07325.2 - 0.0084 17.0 0.6 0.0084 17.0 0.6 5.2 3 2 1 4 4 4 1 Altered inheritance of mitochondria protein 3 RFX5_N PF18326.1 EEB07325.2 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 RFX5 N-terminal domain SPX PF03105.19 EEB07325.2 - 0.33 10.8 12.8 0.1 12.5 9.9 1.6 1 1 1 2 2 2 0 SPX domain Pro_isomerase PF00160.21 EEB07326.2 - 2.6e-49 167.5 0.1 3.3e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIM PF08194.12 EEB07326.2 - 0.053 13.7 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 DIM protein Atg8 PF02991.16 EEB07327.1 - 2e-50 169.3 0.2 2.3e-50 169.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EEB07327.1 - 4.4e-07 30.2 0.0 5.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HopW1-1 PF15457.6 EEB07328.2 - 0.056 12.7 2.5 0.11 11.8 2.5 1.4 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA zf-C3HC4_2 PF13923.6 EEB07328.2 - 0.1 12.4 0.9 0.2 11.5 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EEB07328.2 - 0.22 11.3 1.7 0.41 10.5 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FACT-Spt16_Nlob PF14826.6 EEB07329.1 - 1.1e-55 187.9 0.2 2.3e-55 186.8 0.2 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 EEB07329.1 - 1.5e-54 184.3 0.1 1.5e-54 184.3 0.1 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EEB07329.1 - 6.1e-29 101.2 0.0 1.4e-28 100.1 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EEB07329.1 - 5.5e-17 62.0 0.1 1.7e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Adeno_E1B_19K PF01691.16 EEB07329.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Methyltr_RsmB-F PF01189.17 EEB07330.1 - 5.8e-73 244.8 0.0 9.9e-73 244.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EEB07330.1 - 5.2e-09 36.5 0.0 1.4e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EEB07330.1 - 0.00073 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DUF2431 PF10354.9 EEB07330.1 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FAM219A PF15260.6 EEB07330.1 - 0.092 13.1 3.4 0.29 11.5 3.4 1.8 1 0 0 1 1 1 0 Protein family FAM219A ER_lumen_recept PF00810.18 EEB07331.1 - 2.2e-47 161.6 8.9 3.9e-47 160.8 8.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EEB07331.1 - 4.3e-06 26.4 3.9 0.0071 16.1 0.9 2.8 2 0 0 2 2 2 2 PQ loop repeat UCH PF00443.29 EEB07332.1 - 5.5e-44 150.6 0.0 7.9e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB07332.1 - 2.1e-06 27.6 0.0 0.00011 22.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EEB07332.1 - 0.057 12.9 0.1 3.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Phos_pyr_kin PF08543.12 EEB07333.2 - 7.5e-80 267.9 0.2 1e-79 267.4 0.2 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EEB07333.2 - 1.2e-54 185.3 0.2 1.6e-54 184.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 EEB07333.2 - 0.00012 21.5 0.1 0.00044 19.7 0.0 2.0 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.24 EEB07333.2 - 0.018 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEB07334.1 - 3.6e-76 255.8 0.9 5.1e-76 255.3 0.9 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EEB07334.1 - 1.5e-25 90.2 0.3 2.4e-25 89.6 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family GDI PF00996.18 EEB07335.1 - 8.6e-232 769.2 0.0 1e-231 769.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 EEB07335.1 - 0.00029 20.2 0.0 0.00041 19.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase WD40 PF00400.32 EEB07336.1 - 3.2e-17 62.6 9.3 0.00098 19.9 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07336.1 - 1.5e-07 31.6 1.3 0.032 14.5 0.1 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB07336.1 - 1.4e-06 27.6 0.1 0.085 11.8 0.0 3.8 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DCP1 PF06058.13 EEB07336.1 - 0.082 12.8 0.4 8.2 6.4 0.1 2.6 2 1 0 2 2 2 0 Dcp1-like decapping family NTF2 PF02136.20 EEB07337.1 - 1.4e-35 122.4 0.8 1.6e-35 122.3 0.8 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EEB07337.1 - 0.0017 18.7 0.0 0.002 18.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 EEB07337.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4518 PF15008.6 EEB07337.1 - 0.14 11.3 1.1 0.8 8.8 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Pkinase PF00069.25 EEB07338.2 - 3.7e-68 229.8 0.0 4.9e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07338.2 - 5.4e-30 104.5 0.0 7.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEB07338.2 - 1.8e-10 41.4 5.3 7.5e-10 39.4 5.3 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEB07338.2 - 3.3e-08 33.2 0.0 5.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 EEB07338.2 - 8.6e-07 29.2 0.0 0.00053 20.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 EEB07338.2 - 0.00049 19.1 0.3 0.0012 17.8 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEB07338.2 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEB07338.2 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB07338.2 - 0.072 12.7 0.1 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Brix PF04427.18 EEB07339.1 - 1.8e-48 165.2 0.3 2.7e-48 164.7 0.3 1.2 1 0 0 1 1 1 1 Brix domain Baculo_PP31 PF05311.11 EEB07339.1 - 0.11 12.0 3.8 0.18 11.2 3.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_S49_N PF08496.10 EEB07339.1 - 0.26 11.3 5.7 0.52 10.4 5.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal tRNA-synt_1 PF00133.22 EEB07340.1 - 3.6e-148 494.5 0.0 1.9e-146 488.8 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEB07340.1 - 2.1e-18 66.3 1.1 1.2e-10 40.7 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEB07340.1 - 5e-16 59.0 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EEB07340.1 - 4.6e-05 23.0 0.1 0.0039 16.7 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EEB07340.1 - 6e-05 22.5 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EEB07340.1 - 0.0026 16.7 0.0 1.3 7.8 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 EEB07340.1 - 0.0044 16.4 0.1 0.032 13.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) DAGK_cat PF00781.24 EEB07341.2 - 1e-25 89.8 0.0 1.7e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 EEB07341.2 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Abhydrolase_3 PF07859.13 EEB07342.1 - 8.3e-28 97.7 0.0 1.4e-19 70.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EEB07342.1 - 2.5e-12 46.4 0.0 2.6e-09 36.4 0.1 2.4 2 1 0 2 2 2 2 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EEB07342.1 - 0.0056 16.0 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEB07342.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF4569 PF15133.6 EEB07342.1 - 0.058 13.1 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Myosin_head PF00063.21 EEB07343.1 - 2.6e-261 868.7 5.5 2.6e-261 868.7 5.5 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) PRK PF00485.18 EEB07343.1 - 0.016 15.0 1.4 2 8.1 0.1 3.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EEB07343.1 - 0.041 14.1 8.0 0.11 12.7 0.1 4.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EEB07343.1 - 0.048 13.7 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EEB07343.1 - 0.054 13.8 9.3 0.19 12.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EEB07343.1 - 0.094 13.1 0.0 0.094 13.1 0.0 5.2 5 2 0 5 5 5 0 AAA ATPase domain Pax7 PF12360.8 EEB07343.1 - 0.3 11.3 1.5 0.55 10.5 0.5 2.0 2 0 0 2 2 2 0 Paired box protein 7 NuiA PF07924.11 EEB07343.1 - 10 6.6 17.5 33 4.9 1.2 5.2 3 1 1 4 4 4 0 Nuclease A inhibitor-like protein Peptidase_S8 PF00082.22 EEB07344.1 - 1.7e-38 132.6 8.9 3e-38 131.8 8.9 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEB07344.1 - 9.8e-13 48.6 0.2 1.9e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 PP2C PF00481.21 EEB07345.1 - 4.4e-41 141.2 0.0 3.4e-40 138.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EEB07345.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) UPF0047 PF01894.17 EEB07346.2 - 8.4e-37 125.8 0.0 1.1e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Alpha-amylase PF00128.24 EEB07347.1 - 3.9e-54 184.5 0.0 5.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EEB07347.1 - 2.2e-07 31.0 0.2 1.6e-06 28.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 EEB07347.1 - 0.03 13.4 0.1 0.077 12.1 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase-like 10 hDGE_amylase PF14701.6 EEB07347.1 - 0.054 12.6 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain IMS PF00817.20 EEB07347.1 - 0.08 12.9 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 impB/mucB/samB family CTXphi_pIII-N1 PF16710.5 EEB07347.1 - 0.14 12.3 0.0 0.88 9.7 0.0 2.1 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Glyco_hydro_70 PF02324.16 EEB07347.1 - 0.19 9.9 0.0 0.3 9.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 WD40 PF00400.32 EEB07348.1 - 9.1e-33 111.8 5.7 1.6e-08 35.1 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07348.1 - 3.8e-19 68.8 0.2 4.9e-05 23.5 0.0 5.1 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEB07348.1 - 3e-10 39.9 0.0 0.0032 16.8 0.0 3.4 2 2 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 EEB07348.1 - 5.3e-06 26.4 0.0 0.037 13.9 0.1 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEB07348.1 - 0.042 12.5 0.0 0.28 9.8 0.0 2.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 EEB07348.1 - 0.092 12.1 0.1 8.9 5.5 0.1 2.7 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal EMC1_C PF07774.13 EEB07349.1 - 1.6e-65 220.8 0.1 2.8e-65 220.0 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 EEB07349.1 - 0.0072 16.2 0.0 41 4.4 0.0 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat IMP2_C PF18591.1 EEB07349.1 - 0.015 15.2 0.2 0.48 10.3 0.1 2.6 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain DUF1515 PF07439.11 EEB07350.1 - 0.044 13.8 0.2 0.056 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CAF1C_H4-bd PF12265.8 EEB07351.1 - 3.7e-19 68.7 0.3 1.8e-18 66.5 0.1 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEB07351.1 - 3.5e-05 24.5 6.3 0.59 11.1 0.2 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat SARAF PF06682.12 EEB07352.1 - 0.085 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ATG101 PF07855.12 EEB07353.1 - 3.2e-29 101.9 0.0 3.8e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 CBS PF00571.28 EEB07353.1 - 0.023 15.2 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 CBS domain JmjC PF02373.22 EEB07354.1 - 5.9e-18 65.3 0.0 1.6e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EEB07354.1 - 1.6e-14 54.2 0.0 2.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Avl9 PF09794.9 EEB07356.1 - 2.6e-116 388.4 0.0 3.2e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EEB07356.1 - 1.3e-06 28.2 0.0 0.017 14.7 0.1 2.7 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EEB07356.1 - 7.6e-06 25.9 0.0 0.052 13.5 0.0 2.5 1 1 1 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 EEB07356.1 - 0.00096 19.6 0.1 0.0021 18.5 0.1 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking G-alpha PF00503.20 EEB07357.1 - 4.5e-98 328.7 4.6 5.6e-98 328.4 4.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEB07357.1 - 3.7e-14 52.6 0.3 1.1e-09 38.0 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB07357.1 - 0.00041 19.8 2.7 0.05 12.9 0.2 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB07357.1 - 0.0028 17.7 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 EEB07357.1 - 0.0039 17.4 0.2 2.1 8.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EEB07357.1 - 0.015 14.8 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 EEB07357.1 - 0.019 14.4 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EEB07357.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mit_KHE1 PF10173.9 EEB07358.1 - 6.9e-44 150.2 0.3 8.3e-44 150.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related SKN1 PF03935.15 EEB07359.2 - 5.3e-200 665.1 0.9 7.9e-200 664.5 0.9 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SWIRM PF04433.17 EEB07360.1 - 1.9e-29 101.8 0.0 6e-29 100.2 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EEB07360.1 - 1.7e-22 79.2 7.2 3.9e-22 78.0 7.2 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EEB07360.1 - 3.6e-11 43.1 0.0 6.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB07360.1 - 1e-07 32.1 0.1 2.7e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEB07360.1 - 0.0095 16.1 1.1 0.017 15.3 0.2 1.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EEB07360.1 - 0.024 14.5 0.0 0.081 12.8 0.0 1.9 1 0 0 1 1 1 0 Myb DNA-binding like SRP9-21 PF05486.12 EEB07360.1 - 0.098 13.1 4.0 0.33 11.4 0.4 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Chordopox_RPO7 PF05864.12 EEB07360.1 - 1.1 9.5 3.3 3.3 8.0 0.6 2.5 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Zn_ribbon_2 PF12674.7 EEB07360.1 - 2 9.1 5.6 0.83 10.4 1.8 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain Beta_elim_lyase PF01212.21 EEB07361.1 - 1.6e-84 283.7 0.0 2e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EEB07361.1 - 0.00034 19.9 0.0 0.00051 19.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEB07361.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PreAtp-grasp PF18604.1 EEB07361.1 - 0.0059 16.3 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Pre ATP-grasp domain Cys_Met_Meta_PP PF01053.20 EEB07361.1 - 0.0078 14.8 0.0 0.015 13.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GGDEF_2 PF17853.1 EEB07361.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.9 3 0 0 3 3 3 0 GGDEF-like domain WD40 PF00400.32 EEB07362.1 - 4.9e-07 30.4 5.1 0.03 15.2 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07362.1 - 0.0073 16.6 0.0 3.4 8.0 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Phage_holin_3_5 PF16085.5 EEB07362.1 - 0.14 12.3 0.0 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III Ribosomal_S14 PF00253.21 EEB07363.2 - 2.6e-18 65.5 1.1 3.4e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Adaptin_N PF01602.20 EEB07364.1 - 2e-88 297.2 13.2 2.6e-88 296.9 13.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEB07364.1 - 2.6e-16 60.1 6.1 2.5e-15 56.9 0.0 4.0 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEB07364.1 - 1.1e-09 38.5 3.7 0.00013 22.3 0.1 3.7 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EEB07364.1 - 1.5e-06 27.9 6.8 0.2 12.0 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat Cnd3 PF12719.7 EEB07364.1 - 0.0011 18.3 0.2 0.0011 18.3 0.2 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EEB07364.1 - 0.054 14.0 3.5 1.2e+02 3.4 0.0 5.5 6 0 0 6 6 6 0 HEAT-like repeat Cohesin_HEAT PF12765.7 EEB07364.1 - 0.13 12.6 0.9 4.4 7.7 0.5 3.5 2 1 1 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Merozoite_SPAM PF07133.11 EEB07364.1 - 0.52 10.3 17.0 0.36 10.8 14.5 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) FAM176 PF14851.6 EEB07364.1 - 5.9 6.5 10.4 12 5.5 10.4 1.6 1 0 0 1 1 1 0 FAM176 family Prp18 PF02840.15 EEB07365.1 - 6.1e-49 165.7 0.1 6.1e-49 165.7 0.1 2.7 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 EEB07365.1 - 5e-06 25.9 0.0 1.5e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Oxysterol_BP PF01237.18 EEB07365.1 - 0.87 8.3 16.7 0.033 13.0 10.4 1.7 2 0 0 2 2 2 0 Oxysterol-binding protein SRP19 PF01922.17 EEB07366.1 - 2.1e-21 76.6 0.0 3.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein ABC_membrane PF00664.23 EEB07367.2 - 2.5e-34 119.2 9.8 3.5e-34 118.7 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEB07367.2 - 1.1e-16 61.6 0.0 3.3e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEB07367.2 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EEB07367.2 - 0.018 15.2 0.3 0.45 10.8 0.3 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TFIID_20kDa PF03847.13 EEB07368.2 - 6.7e-35 119.4 5.8 4.7e-34 116.7 1.3 2.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EEB07368.2 - 6.5e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EEB07368.2 - 0.00033 20.7 0.8 0.0012 19.0 0.0 2.3 2 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EEB07368.2 - 0.00043 20.6 0.7 0.002 18.5 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF2835 PF11197.8 EEB07368.2 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) FAM199X PF15814.5 EEB07368.2 - 0.56 9.2 3.7 1.1 8.3 3.7 1.5 1 0 0 1 1 1 0 Protein family FAM199X zf-CCCH_4 PF18044.1 EEB07369.2 - 5.1e-08 32.5 0.9 1.1e-07 31.5 0.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EEB07369.2 - 0.00034 20.6 3.9 0.00065 19.7 3.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EEB07369.2 - 0.0011 18.8 0.7 0.0011 18.8 0.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EEB07369.2 - 0.017 15.8 0.4 0.035 14.8 0.4 1.5 1 0 0 1 1 1 0 Torus domain DUF5543 PF17697.1 EEB07369.2 - 0.063 13.6 1.7 0.084 13.2 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5543) SNF2_N PF00176.23 EEB07370.2 - 1.2e-58 198.6 0.0 3e-58 197.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EEB07370.2 - 5.4e-40 137.5 9.3 1.5e-38 132.8 10.7 2.4 2 1 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EEB07370.2 - 3.1e-16 59.7 0.0 1e-15 58.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07370.2 - 9.5e-07 29.0 0.0 2.6e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEB07370.2 - 9.7e-06 25.5 0.1 0.0006 19.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB07370.2 - 2.2e-05 24.8 0.2 0.41 10.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain HDA2-3 PF11496.8 EEB07370.2 - 0.0021 17.3 0.0 0.016 14.4 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 IBB PF01749.20 EEB07370.2 - 0.24 11.8 0.1 0.24 11.8 0.1 2.7 2 0 0 2 2 2 0 Importin beta binding domain zf-ZPR1 PF03367.13 EEB07371.1 - 1.5e-116 385.6 1.1 6.5e-59 198.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EEB07371.1 - 0.011 15.8 6.5 0.16 12.0 0.2 2.6 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Churchill PF06573.11 EEB07371.1 - 0.082 13.2 2.1 0.3 11.4 0.1 2.5 2 1 0 2 2 2 0 Churchill protein Terminase_GpA PF05876.12 EEB07371.1 - 0.12 10.9 2.3 0.25 9.9 0.1 2.3 2 1 1 3 3 3 0 Phage terminase large subunit (GpA) zinc-ribbons_6 PF07191.12 EEB07371.1 - 0.69 9.9 5.1 2.4 8.2 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 EEB07371.1 - 2.8 7.9 10.6 7.5 6.6 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EEB07371.1 - 9.8 6.0 9.2 32 4.4 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain YjeF_N PF03853.15 EEB07372.2 - 3.8e-36 124.6 0.0 4.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Sulfate_transp PF00916.20 EEB07373.1 - 2.6e-120 401.7 17.2 3.4e-120 401.3 17.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEB07373.1 - 8.7e-13 47.9 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EEB07373.1 - 0.011 16.1 1.5 0.011 16.1 1.5 3.0 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EEB07373.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 STAS domain Transket_pyr PF02779.24 EEB07374.1 - 3.4e-63 212.5 0.0 7.4e-63 211.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EEB07374.1 - 3.7e-60 203.4 0.0 5.6e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EEB07374.1 - 4.4e-51 172.6 0.0 7.4e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EEB07374.1 - 1.4e-19 69.3 1.2 1.4e-19 69.3 1.2 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus CENP-X PF09415.10 EEB07375.1 - 1.6e-21 76.4 0.2 1.8e-21 76.2 0.2 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X BCNT PF07572.12 EEB07376.1 - 5.5e-17 61.6 1.4 1.2e-16 60.5 1.4 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development TEX19 PF15553.6 EEB07376.1 - 3.6 7.5 5.2 6 6.8 5.2 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 TP_methylase PF00590.20 EEB07377.1 - 3.4e-24 86.0 0.1 5.6e-24 85.3 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.25 EEB07378.1 - 5.4e-65 219.4 0.0 7.1e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07378.1 - 2.9e-33 115.3 0.0 4.5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 EEB07378.1 - 7.7e-08 32.4 0.0 2.5e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EEB07378.1 - 3.7e-05 23.2 0.0 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEB07378.1 - 0.0002 21.4 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEB07378.1 - 0.00083 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEB07378.1 - 0.0012 17.9 0.4 0.0021 17.1 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EEB07378.1 - 0.0074 15.9 0.9 0.63 9.6 0.2 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEB07378.1 - 0.028 14.0 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EEB07378.1 - 0.039 13.6 0.2 0.073 12.7 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EEB07378.1 - 0.039 13.0 0.1 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EEB07378.1 - 0.04 12.7 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EEB07378.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL LSM PF01423.22 EEB07379.1 - 9.2e-18 63.7 0.3 1.1e-17 63.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB07379.1 - 0.0091 16.1 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LRR_9 PF14580.6 EEB07379.1 - 0.039 13.5 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat DUF1461 PF07314.11 EEB07379.1 - 0.068 13.1 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DASH_Spc34 PF08657.10 EEB07380.1 - 3.5e-10 40.1 8.4 0.0001 22.2 0.2 2.2 1 1 0 2 2 2 2 DASH complex subunit Spc34 Bacillus_HBL PF05791.11 EEB07380.1 - 0.00031 20.6 0.2 0.00049 20.0 0.2 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) EspA PF03433.13 EEB07380.1 - 0.0038 17.1 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 EspA-like secreted protein FTA4 PF13093.6 EEB07380.1 - 0.32 10.9 3.6 0.42 10.5 3.6 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3398 PF11878.8 EEB07381.1 - 0.022 15.2 0.8 0.042 14.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF3130 PF11328.8 EEB07381.1 - 0.067 13.4 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 FlxA PF14282.6 EEB07381.1 - 0.22 11.5 12.9 0.17 11.9 10.6 2.1 1 1 1 2 2 2 0 FlxA-like protein L27_1 PF09058.10 EEB07381.1 - 0.36 10.9 6.4 0.1 12.6 1.4 2.5 3 0 0 3 3 3 0 L27_1 FUSC PF04632.12 EEB07381.1 - 1.5 7.2 3.0 1.6 7.1 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metal_resist PF13801.6 EEB07381.1 - 1.7 8.8 8.9 3.9 7.7 8.9 1.6 1 1 0 1 1 1 0 Heavy-metal resistance DUF2229 PF09989.9 EEB07381.1 - 2.3 7.8 4.4 4.7 6.8 4.4 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) TLD PF07534.16 EEB07382.1 - 1.1e-24 87.3 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 TLD W2 PF02020.18 EEB07383.1 - 1.5e-16 60.3 0.0 1.5e-16 60.3 0.0 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EEB07383.1 - 5.9e-16 57.5 38.3 3.8e-07 29.6 4.4 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EEB07383.1 - 8.3e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EEB07383.1 - 1.7e-05 24.5 15.5 0.00017 21.3 1.3 4.2 2 1 3 5 5 5 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EEB07383.1 - 0.0023 16.2 4.4 0.0037 15.5 0.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EEB07383.1 - 0.0039 17.6 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EEB07383.1 - 0.0041 16.1 8.4 0.2 10.5 0.2 3.1 2 1 1 3 3 3 2 L-fucokinase HSF_DNA-bind PF00447.17 EEB07384.2 - 2e-26 92.4 1.3 1.3e-23 83.4 1.3 2.7 1 1 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EEB07384.2 - 6.6e-21 74.6 1.2 1.2e-20 73.7 0.3 2.0 2 0 0 2 2 2 1 Response regulator receiver domain Mito_carr PF00153.27 EEB07385.1 - 8e-60 198.8 5.0 5.6e-22 77.5 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB07385.1 - 0.0034 16.6 0.2 2.1 7.4 0.0 2.6 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF5310 PF17237.2 EEB07386.1 - 2.5e-22 78.4 2.0 3e-22 78.2 2.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) BolA PF01722.18 EEB07387.2 - 6e-17 61.7 0.1 1.8e-16 60.2 0.1 1.7 1 1 0 1 1 1 1 BolA-like protein RRP14 PF15459.6 EEB07388.1 - 6e-08 33.2 2.9 6e-08 33.2 2.9 2.8 2 1 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 SRP-alpha_N PF04086.13 EEB07388.1 - 2.9 7.8 18.1 3.6 7.4 18.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S49_N PF08496.10 EEB07388.1 - 6.1 6.9 14.1 3.2 7.8 1.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Il13Ra_Ig PF18001.1 EEB07389.1 - 0.2 11.8 1.3 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain Ribosomal_S7 PF00177.21 EEB07391.1 - 1.7e-36 125.1 1.9 2.2e-36 124.8 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SUN PF03856.13 EEB07392.1 - 2.4e-77 259.7 11.6 3.4e-77 259.2 11.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_S2 PF00318.20 EEB07393.1 - 1.7e-25 89.5 0.4 8.8e-14 51.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EEB07393.1 - 1.2e-07 33.0 14.1 2.4e-07 32.0 14.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus COX14 PF14880.6 EEB07394.1 - 3.9e-06 26.6 0.1 6.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly PDEase_II PF02112.15 EEB07395.2 - 1.2e-67 228.4 5.5 4.2e-62 210.2 4.6 2.1 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EEB07395.2 - 0.0043 16.6 0.3 0.0097 15.4 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain CTU2 PF10288.9 EEB07395.2 - 0.38 11.0 3.3 7.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Clat_adaptor_s PF01217.20 EEB07396.2 - 5e-11 42.7 0.1 8.4e-11 42.0 0.1 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Trp_repressor PF01371.19 EEB07396.2 - 0.03 14.4 0.1 0.12 12.5 0.2 2.1 2 1 0 2 2 2 0 Trp repressor protein Type2_restr_D3 PF16902.5 EEB07396.2 - 0.073 13.0 1.6 0.16 11.9 0.3 2.1 2 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain DUF2420 PF10336.9 EEB07397.1 - 4.4e-16 58.8 0.0 9e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mito_carr PF00153.27 EEB07398.1 - 9.7e-69 227.4 4.6 6.9e-26 90.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinetochor_Ybp2 PF08568.10 EEB07399.1 - 1e-29 103.5 11.2 5.3e-18 64.9 4.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin RasGEF PF00617.19 EEB07400.1 - 8.7e-46 156.3 2.1 1e-44 152.8 0.2 2.8 2 0 0 2 2 2 1 RasGEF domain SH3_2 PF07653.17 EEB07400.1 - 3.8e-09 36.1 0.0 8.2e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEB07400.1 - 2.6e-07 30.1 0.0 5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.20 EEB07400.1 - 5.4e-07 29.8 2.3 5.4e-07 29.8 2.3 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_9 PF14604.6 EEB07400.1 - 8.4e-07 28.8 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF3336 PF11815.8 EEB07401.1 - 2.7e-32 111.4 0.8 4.6e-32 110.6 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEB07401.1 - 6.6e-12 46.0 0.1 1.2e-11 45.2 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PIG-F PF06699.11 EEB07402.1 - 4.3e-49 167.1 10.2 7.6e-49 166.3 10.2 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F adh_short PF00106.25 EEB07402.1 - 2.3e-29 102.2 0.0 3.6e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB07402.1 - 6.9e-15 55.2 0.0 9.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB07402.1 - 1.2e-11 44.9 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEB07402.1 - 5.9e-07 29.2 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EEB07402.1 - 0.00039 19.9 0.0 0.0056 16.1 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EEB07402.1 - 0.0029 16.9 0.2 0.0069 15.7 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EEB07402.1 - 0.0059 16.0 0.1 0.027 13.9 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EEB07402.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ERO1 PF04137.15 EEB07403.1 - 1.2e-115 386.5 0.2 1.6e-115 386.1 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3447 PF11929.8 EEB07403.1 - 0.9 9.5 5.2 6.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) Mei4 PF13971.6 EEB07404.1 - 1.1e-06 28.4 4.6 1.5e-06 27.9 4.6 1.1 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 BLM10_mid PF16507.5 EEB07404.1 - 0.009 14.7 0.4 0.038 12.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF4640 PF15480.6 EEB07404.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) HetR_C PF18460.1 EEB07404.1 - 0.015 15.2 0.3 0.036 14.0 0.3 1.6 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Lum_binding PF00677.17 EEB07405.1 - 6.1e-46 154.3 2.3 9.7e-23 80.0 0.4 2.1 2 0 0 2 2 2 2 Lumazine binding domain Ribosomal_L21p PF00829.21 EEB07405.1 - 0.016 15.5 1.0 0.07 13.4 0.0 2.4 2 1 1 3 3 3 0 Ribosomal prokaryotic L21 protein NAC PF01849.18 EEB07405.1 - 0.085 12.8 0.0 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 NAC domain Cadherin_5 PF17892.1 EEB07405.1 - 0.1 12.6 0.4 0.74 9.8 0.1 2.4 2 1 1 3 3 3 0 Cadherin-like domain DUF3818 PF12825.7 EEB07406.1 - 1.1e-102 343.6 1.0 2e-102 342.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EEB07406.1 - 1.7e-25 89.5 2.9 2.1e-25 89.2 0.9 2.3 2 0 0 2 2 2 1 PX-associated PX PF00787.24 EEB07406.1 - 2.1e-09 37.4 0.5 5.9e-09 35.9 0.5 1.8 1 0 0 1 1 1 1 PX domain RPN5_C PF18098.1 EEB07406.1 - 0.085 13.0 0.2 4.5 7.5 0.2 2.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain EF1_GNE PF00736.19 EEB07407.1 - 8.7e-33 112.4 3.1 1.1e-32 112.1 1.5 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EEB07407.1 - 1.3e-12 47.9 3.1 4.2e-12 46.3 3.1 2.0 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 EEB07407.1 - 0.0067 16.4 0.2 0.018 15.0 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EEB07407.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UBA2_C PF16195.5 EEB07407.1 - 0.026 15.2 0.9 0.049 14.3 0.9 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF211 PF02680.14 EEB07407.1 - 0.066 13.4 0.5 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Rox3 PF08633.10 EEB07408.1 - 1.6e-12 48.2 0.1 4.4e-10 40.2 0.3 2.0 1 1 1 2 2 2 2 Rox3 mediator complex subunit Glutaredoxin PF00462.24 EEB07409.1 - 3.8e-14 52.6 0.0 7.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DUF929 PF06053.11 EEB07409.1 - 0.062 12.6 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DAO PF01266.24 EEB07410.1 - 2.5e-30 106.3 1.6 4.2e-30 105.5 1.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EEB07410.1 - 0.0029 16.9 0.3 0.0075 15.5 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EEB07410.1 - 0.0046 16.2 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EEB07410.1 - 0.0054 16.0 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEB07410.1 - 0.011 16.3 0.4 0.023 15.2 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEB07410.1 - 0.016 15.4 0.5 0.038 14.2 0.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EEB07410.1 - 0.043 13.1 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEB07410.1 - 0.049 12.7 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EEB07410.1 - 0.18 10.9 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EEB07410.1 - 0.18 11.1 0.1 0.36 10.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fe_hyd_lg_C PF02906.14 EEB07411.1 - 2.1e-61 207.7 0.0 3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.25 EEB07412.1 - 3.9e-60 203.4 0.0 3.4e-39 134.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07412.1 - 2.8e-25 89.1 0.0 1.4e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB07412.1 - 3.7e-07 29.8 0.0 0.00054 19.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEB07412.1 - 0.0013 18.7 0.1 0.0054 16.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEB07412.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Response_reg PF00072.24 EEB07412.1 - 0.0026 17.9 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain CHASE7 PF17151.4 EEB07412.1 - 0.0096 15.5 0.6 5.4 6.6 0.1 2.5 2 0 0 2 2 2 2 Periplasmic sensor domain Haspin_kinase PF12330.8 EEB07412.1 - 0.044 12.7 0.0 0.044 12.7 0.0 2.5 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EEB07412.1 - 0.072 12.1 0.2 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 PIN_8 PF18476.1 EEB07412.1 - 0.35 10.7 3.4 4.8 7.0 1.3 2.9 3 0 0 3 3 3 0 PIN like domain Utp12 PF04003.12 EEB07413.1 - 3.1e-12 46.8 0.6 4.1e-12 46.3 0.6 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family CARD_2 PF16739.5 EEB07413.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain SDA1 PF05285.12 EEB07413.1 - 0.45 9.9 27.4 0.57 9.6 27.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EEB07413.1 - 1.9 7.7 25.6 3 7.1 25.6 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EEB07413.1 - 9.6 4.3 30.3 12 3.9 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 EEB07413.1 - 9.6 5.1 13.9 0.19 10.7 7.5 1.4 2 0 0 2 2 2 0 Solute carrier family 12 Bromodomain PF00439.25 EEB07414.2 - 7.1e-52 173.4 0.1 3.2e-25 88.0 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EEB07414.2 - 4.5e-15 55.6 0.0 1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 EEB07414.2 - 0.2 11.7 6.1 0.25 11.4 0.5 3.3 3 0 0 3 3 3 0 FlxA-like protein DUF1690 PF07956.11 EEB07414.2 - 0.37 11.2 7.6 4.7 7.6 0.1 2.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF3381 PF11861.8 EEB07414.2 - 0.42 10.4 4.9 0.072 12.9 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SlyX PF04102.12 EEB07414.2 - 0.79 10.4 4.0 6.6 7.4 0.1 3.1 3 0 0 3 3 3 0 SlyX Med21 PF11221.8 EEB07414.2 - 3.7 7.8 8.6 21 5.4 1.1 3.9 3 1 0 3 3 3 0 Subunit 21 of Mediator complex ApoO PF09769.9 EEB07415.1 - 4.1e-21 75.3 0.7 4.5e-20 71.9 0.0 2.0 1 1 1 2 2 2 1 Apolipoprotein O Apo-CIII PF05778.12 EEB07415.1 - 0.15 11.8 4.4 0.34 10.6 0.7 2.7 3 1 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Proteasome PF00227.26 EEB07416.1 - 4e-60 202.6 0.1 5.1e-60 202.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB07416.1 - 1.8e-09 37.1 1.6 3.1e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature WLM PF08325.10 EEB07417.1 - 1.3e-39 136.3 0.7 2.8e-39 135.2 0.2 1.6 1 1 1 2 2 2 1 WLM domain ubiquitin PF00240.23 EEB07417.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF45 PF01863.17 EEB07417.1 - 0.00038 20.5 2.6 0.00073 19.6 1.5 1.9 1 1 1 2 2 2 1 Protein of unknown function DUF45 COX6B PF02297.17 EEB07418.1 - 1.3e-19 70.2 6.9 1.6e-19 69.9 6.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 EEB07418.1 - 0.0066 16.6 0.8 0.015 15.4 0.8 1.7 1 1 0 1 1 1 1 CHCH domain Chorismate_bind PF00425.18 EEB07419.1 - 1.7e-93 312.9 0.0 4.3e-93 311.6 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EEB07419.1 - 1.3e-24 87.0 0.6 5.1e-22 78.6 0.1 3.9 2 2 0 3 3 3 1 Anthranilate synthase component I, N terminal region RNA_pol_A_bac PF01000.26 EEB07420.1 - 3.7e-32 111.0 0.0 6.9e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEB07420.1 - 1.1e-19 69.6 0.0 1.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain L51_S25_CI-B8 PF05047.16 EEB07421.1 - 2.2e-06 27.5 0.1 3.9e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EF_TS PF00889.19 EEB07422.1 - 1.6e-16 60.6 0.1 8.8e-16 58.1 0.0 2.1 2 1 1 3 3 3 1 Elongation factor TS ISP3_C PF18045.1 EEB07422.1 - 0.015 15.2 0.2 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 ISP3 C-terminal HTH_57 PF18679.1 EEB07422.1 - 0.048 14.0 0.3 0.17 12.2 0.1 2.0 2 1 0 2 2 2 0 ThcOx helix turn helix domain Brix PF04427.18 EEB07423.1 - 2e-39 135.7 0.3 3e-39 135.1 0.3 1.3 1 0 0 1 1 1 1 Brix domain Dicty_REP PF05086.12 EEB07423.1 - 0.005 14.9 0.2 0.0071 14.4 0.2 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Tubulin PF00091.25 EEB07424.1 - 3.6e-67 226.4 0.0 5.3e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEB07424.1 - 4.2e-50 169.1 0.0 6.8e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EEB07424.1 - 0.0018 18.0 0.0 0.0046 16.6 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L37ae PF01780.19 EEB07425.1 - 6.4e-37 125.5 8.0 7.2e-37 125.3 8.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EEB07425.1 - 0.0095 15.9 3.7 0.016 15.1 3.7 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 EEB07425.1 - 0.014 15.4 0.9 0.024 14.7 0.9 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Lar_restr_allev PF14354.6 EEB07425.1 - 0.032 14.6 0.2 0.051 14.0 0.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.6 EEB07425.1 - 0.04 14.3 0.6 0.18 12.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.10 EEB07425.1 - 0.05 13.3 3.5 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Sgf11 PF08209.11 EEB07425.1 - 0.22 11.1 2.8 11 5.6 0.8 2.4 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.26 EEB07425.1 - 0.78 10.3 4.0 2.8 8.6 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 EEB07425.1 - 4.3 7.3 6.1 0.39 10.7 1.4 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type EF-hand_4 PF12763.7 EEB07426.2 - 2.9e-36 123.6 0.0 2.2e-13 50.0 0.0 3.8 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EEB07426.2 - 1.6e-08 34.9 0.0 7.4e-05 23.1 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB07426.2 - 4.7e-05 22.6 0.0 2.1 8.1 0.0 4.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EEB07426.2 - 0.0012 18.6 0.1 1.8 8.7 0.1 4.5 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 EEB07426.2 - 0.013 15.4 0.0 2.6 8.0 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain pair THOC7 PF05615.13 EEB07426.2 - 1 9.6 37.2 0.05 13.9 13.5 3.8 1 1 3 4 4 4 0 Tho complex subunit 7 ubiquitin PF00240.23 EEB07427.1 - 4.5e-08 32.7 0.2 6.6e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 EEB07427.1 - 0.0036 17.6 0.2 0.0044 17.3 0.2 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 EEB07427.1 - 0.0044 17.1 0.2 0.029 14.5 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEB07427.1 - 0.043 14.4 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB07427.1 - 0.068 13.5 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 EEB07427.1 - 0.069 13.6 0.2 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 CENP-T_C PF15511.6 EEB07428.1 - 1.7e-36 124.6 1.3 4e-36 123.4 1.3 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EEB07428.1 - 8.4e-10 38.9 0.4 1.9e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EEB07428.1 - 8.5e-05 22.9 0.4 8.5e-05 22.9 0.4 2.8 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EEB07428.1 - 0.0016 18.5 1.1 0.006 16.6 0.4 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EEB07428.1 - 0.0022 18.3 0.0 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EEB07428.1 - 0.0085 16.1 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Striatin PF08232.12 EEB07429.2 - 3.6e-24 86.1 10.1 1.7e-23 84.0 10.1 2.0 1 1 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 EEB07429.2 - 6.7e-11 42.3 0.0 0.16 12.3 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB07429.2 - 1.3e-07 32.2 4.5 0.11 13.4 0.1 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat WD40_like PF17005.5 EEB07429.2 - 0.00086 18.7 0.4 0.0046 16.3 0.2 2.0 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EEB07429.2 - 0.003 16.6 0.1 0.18 10.7 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEB07429.2 - 0.0072 15.0 1.0 0.17 10.5 0.1 2.6 1 1 2 3 3 3 1 Nucleoporin Nup120/160 betaPIX_CC PF16523.5 EEB07429.2 - 0.013 15.3 3.8 0.088 12.6 0.7 3.0 3 0 0 3 3 3 0 betaPIX coiled coil PQQ_2 PF13360.6 EEB07429.2 - 0.054 13.1 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain RasGAP_C PF03836.15 EEB07429.2 - 0.072 13.2 1.9 0.089 12.9 1.0 1.6 1 1 0 1 1 1 0 RasGAP C-terminus LMBR1 PF04791.16 EEB07429.2 - 1.5 7.6 5.8 2.2 7.1 5.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AhpC-TSA PF00578.21 EEB07430.1 - 3.4e-25 88.3 0.0 4.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEB07430.1 - 8.8e-18 64.4 0.0 9.7e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EEB07430.1 - 0.00036 20.6 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF905 PF06006.12 EEB07430.1 - 0.018 15.0 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) CDC50 PF03381.15 EEB07431.1 - 1.3e-95 320.2 0.0 1.5e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4812 PF16071.5 EEB07431.1 - 7.6 6.4 6.7 1.5 8.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4812) tRNA-synt_2 PF00152.20 EEB07432.1 - 2.7e-84 282.9 0.0 3.9e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEB07432.1 - 4.8e-11 42.5 0.0 8.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.31 EEB07433.1 - 5.6e-20 71.2 1.7 1.4e-19 69.9 1.7 1.8 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_15 PF01793.16 EEB07434.1 - 3.4e-93 312.4 14.8 2.5e-90 303.0 14.8 2.1 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ran_BP1 PF00638.18 EEB07435.1 - 2.6e-48 163.3 0.7 2.6e-48 163.3 0.7 1.6 2 0 0 2 2 2 1 RanBP1 domain Lig_C PF18330.1 EEB07435.1 - 0.028 14.4 0.0 0.085 12.9 0.0 1.9 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region SNF2_N PF00176.23 EEB07436.1 - 8e-76 255.0 0.0 1.3e-75 254.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB07436.1 - 6.9e-18 65.0 0.2 2.7e-17 63.1 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EEB07436.1 - 3e-14 52.7 0.0 7.3e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 EEB07436.1 - 8.9e-10 38.8 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_4 PF14555.6 EEB07436.1 - 4.4e-09 36.0 0.2 8.6e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.6 EEB07436.1 - 1.4e-05 24.9 12.6 2.6e-05 24.0 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB07436.1 - 5.1e-05 23.0 15.3 0.00011 22.1 15.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EEB07436.1 - 0.00016 21.0 0.1 0.00031 20.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EEB07436.1 - 0.0041 17.0 13.2 0.0093 15.9 13.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EEB07436.1 - 0.0063 16.8 13.4 0.015 15.6 13.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB07436.1 - 0.01 15.7 10.0 0.023 14.5 10.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB07436.1 - 0.01 15.8 12.2 0.03 14.4 12.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DEAD_2 PF06733.15 EEB07436.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.9 1 0 0 1 1 1 0 DEAD_2 zf-C3HC4_4 PF15227.6 EEB07436.1 - 3.4 7.9 12.4 7.2 6.9 12.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_S3Ae PF01015.18 EEB07437.1 - 5.2e-88 293.9 3.7 6.3e-88 293.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EEB07437.1 - 0.0098 16.4 1.8 0.049 14.2 0.5 2.5 2 1 0 2 2 2 1 Translation initiation factor SUI1 NEMO PF11577.8 EEB07437.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO FtsA PF14450.6 EEB07437.1 - 0.14 12.6 0.1 0.43 11.0 0.0 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Phosphodiest PF01663.22 EEB07438.1 - 2.7e-16 60.1 1.9 2.9e-10 40.3 0.2 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEB07438.1 - 0.00056 19.4 0.1 0.55 9.6 0.0 2.4 2 0 0 2 2 2 2 Sulfatase zf-Tim10_DDP PF02953.15 EEB07439.1 - 5.5e-20 70.8 3.5 5.5e-20 70.8 3.5 1.8 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Polysacc_deac_3 PF15421.6 EEB07439.1 - 0.03 12.8 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Putative polysaccharide deacetylase TRAPP PF04051.16 EEB07440.1 - 2.2e-26 92.3 0.0 2.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phage_connect_1 PF05135.13 EEB07440.1 - 0.023 15.2 0.1 0.07 13.6 0.0 1.8 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Pet127 PF08634.10 EEB07441.1 - 1.5e-92 310.0 0.4 2.2e-92 309.4 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 RNA_pol_Rpb8 PF03870.15 EEB07441.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb8 DUF4279 PF14106.6 EEB07441.1 - 0.15 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DNA_ligase_A_M PF01068.21 EEB07442.1 - 9.2e-53 178.9 0.0 1.9e-52 177.9 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEB07442.1 - 9.9e-33 113.9 0.0 2.4e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EEB07442.1 - 9.9e-16 58.5 0.7 1.3e-14 54.9 0.0 2.8 3 1 0 3 3 3 1 RNA ligase DNA_ligase_A_C PF04679.15 EEB07442.1 - 3.5e-14 53.2 0.0 1.3e-13 51.3 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 EEB07442.1 - 3.7e-11 43.3 0.0 9.2e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EEB07442.1 - 3.3e-07 30.6 0.4 0.0023 18.2 0.0 3.3 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 EEB07442.1 - 7.3e-05 22.7 0.7 0.038 13.8 0.2 3.3 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain DUF5085 PF16895.5 EEB07442.1 - 0.072 13.4 0.1 26 5.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5085) UDG PF03167.19 EEB07443.2 - 7e-21 74.8 0.1 1.2e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PepSY_like PF11396.8 EEB07443.2 - 0.086 13.4 0.7 1.6 9.4 0.4 2.4 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Sld3_N PF18523.1 EEB07443.2 - 0.098 12.8 2.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Sld3 N-terminal domain Sec2p PF06428.11 EEB07444.1 - 2.2e-11 43.6 7.1 3.2e-11 43.0 7.1 1.2 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p mCpol PF18182.1 EEB07444.1 - 0.00022 21.5 1.0 0.00031 21.1 1.0 1.2 1 0 0 1 1 1 1 minimal CRISPR polymerase domain Csm2_III-A PF03750.13 EEB07444.1 - 0.13 13.2 4.0 0.19 12.5 4.0 1.4 1 1 0 1 1 1 0 Csm2 Type III-A S1 PF00575.23 EEB07445.1 - 1.6e-76 252.6 28.0 6.4e-13 48.8 0.4 12.0 11 1 0 11 11 11 11 S1 RNA binding domain Suf PF05843.14 EEB07445.1 - 2.2e-11 44.3 0.2 7e-08 32.8 0.0 4.0 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EEB07445.1 - 2.3e-08 34.4 0.1 0.0008 19.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB07445.1 - 1.2e-05 25.9 0.0 0.057 14.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB07445.1 - 0.0001 22.8 0.4 2.7 9.0 0.1 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EEB07445.1 - 0.00036 20.4 13.2 0.092 12.7 0.0 5.6 7 0 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain TPR_6 PF13174.6 EEB07445.1 - 0.00043 20.7 1.2 0.31 11.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEB07445.1 - 0.016 15.5 0.7 0.95 9.8 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEB07445.1 - 0.087 13.0 0.1 0.27 11.4 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB07445.1 - 0.24 11.6 0.5 32 5.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L1 PF00687.21 EEB07446.1 - 7.8e-46 156.4 1.2 9.7e-46 156.1 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MS_channel PF00924.18 EEB07447.1 - 4.1e-22 78.8 2.4 8.6e-22 77.7 2.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 EEB07447.1 - 0.0038 17.6 0.1 0.01 16.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB07447.1 - 0.021 14.3 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EEB07447.1 - 0.056 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain CCDC-167 PF15188.6 EEB07447.1 - 1.7 9.1 3.4 2 8.8 1.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Bac_rhodopsin PF01036.18 EEB07448.2 - 1.5e-10 41.1 1.3 1.7e-10 40.8 1.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein EamA PF00892.20 EEB07448.2 - 0.022 14.9 0.4 0.043 14.0 0.4 1.4 1 0 0 1 1 1 0 EamA-like transporter family SAP PF02037.27 EEB07449.1 - 1.3e-13 50.3 0.3 2.6e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EEB07449.1 - 2.3e-05 24.1 6.6 0.011 15.6 0.1 3.3 3 1 1 4 4 4 2 Tho1/MOS11 C-terminal domain Ribosomal_L11_N PF03946.14 EEB07450.1 - 3.7e-22 77.9 0.3 6e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EEB07450.1 - 6.8e-18 64.9 0.6 3.2e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 EEB07450.1 - 0.053 13.3 0.0 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region Metallophos PF00149.28 EEB07451.1 - 1.5e-38 133.4 0.2 1.9e-38 133.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEB07451.1 - 1.1e-22 80.2 1.5 2.3e-22 79.1 1.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF5391 PF17369.2 EEB07452.1 - 0.062 13.3 7.8 0.13 12.3 5.8 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5391) WD40 PF00400.32 EEB07453.2 - 3e-05 24.7 0.0 0.0068 17.2 0.0 4.2 4 1 1 5 5 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 EEB07453.2 - 0.00062 19.8 0.3 0.022 14.8 0.0 2.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EEB07453.2 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 WD40-like domain Sec23_trunk PF04811.15 EEB07454.1 - 1.7e-77 260.3 0.0 2.5e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEB07454.1 - 1.4e-31 109.1 0.7 3e-31 108.0 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEB07454.1 - 2.4e-24 85.1 0.0 5.4e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EEB07454.1 - 3e-14 52.7 0.0 6.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EEB07454.1 - 3.5e-14 52.6 7.0 6.4e-14 51.7 7.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EEB07454.1 - 0.16 11.4 0.2 0.67 9.4 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Exo_endo_phos PF03372.23 EEB07455.2 - 4e-24 85.4 0.1 1.5e-23 83.5 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EEB07455.2 - 3.4e-05 24.1 0.3 9.7e-05 22.7 0.3 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEB07455.2 - 0.0045 16.7 0.1 0.0086 15.8 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 EEB07455.2 - 0.28 11.9 1.5 2.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat WD40 PF00400.32 EEB07456.1 - 4.6e-46 153.8 18.5 9.2e-10 39.0 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EEB07456.1 - 1e-41 142.2 1.1 1.7e-41 141.5 1.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EEB07456.1 - 4.7e-11 42.9 0.0 0.06 13.6 0.0 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB07456.1 - 6.7e-06 25.3 0.2 0.95 8.4 0.0 4.3 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EEB07456.1 - 4.8e-05 23.2 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 EEB07456.1 - 8.9e-05 22.0 0.0 0.051 12.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EEB07456.1 - 0.0034 16.1 0.9 6.6 5.2 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Peptidase_C50 PF03568.17 EEB07457.1 - 5e-144 480.3 0.0 6.6e-143 476.6 0.0 2.5 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 EEB07457.1 - 0.0083 15.6 0.1 0.38 10.1 0.0 3.0 2 1 0 2 2 2 1 CHAT domain Hydrolase_4 PF12146.8 EEB07458.1 - 4e-57 193.2 0.0 4.8e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEB07458.1 - 3e-14 53.3 0.0 3.6e-11 43.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB07458.1 - 3.2e-12 47.6 0.0 4.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEB07458.1 - 0.00042 20.2 0.1 1.6 8.5 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EEB07458.1 - 0.0012 18.3 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EEB07458.1 - 0.072 12.7 0.0 0.088 12.4 0.0 1.3 1 1 0 1 1 1 0 Putative esterase SMC_N PF02463.19 EEB07460.1 - 3.1e-26 92.2 0.0 8.4e-26 90.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEB07460.1 - 7.2e-12 46.2 23.8 7.2e-12 46.2 23.8 6.0 4 1 1 5 5 5 2 AAA domain AAA_15 PF13175.6 EEB07460.1 - 1.2e-09 38.4 13.9 1.2e-09 38.4 13.9 3.8 3 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EEB07460.1 - 2.6e-05 23.9 0.1 5.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HOOK PF05622.12 EEB07460.1 - 4.9e-05 21.7 18.5 4.9e-05 21.7 18.5 3.9 3 1 1 4 4 4 2 HOOK protein AAA_21 PF13304.6 EEB07460.1 - 0.0028 17.5 0.1 0.0028 17.5 0.1 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Sugarporin_N PF11471.8 EEB07460.1 - 0.13 12.2 11.1 0.48 10.4 0.0 3.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension CoA_binding_3 PF13727.6 EEB07460.1 - 0.2 11.7 1.2 21 5.1 0.1 3.4 4 0 0 4 4 4 0 CoA-binding domain DUF3110 PF11360.8 EEB07460.1 - 2 8.6 7.8 33 4.8 0.1 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3110) Ribosomal_L27A PF00828.19 EEB07461.1 - 1.1e-20 74.6 0.0 1.5e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Rpr2 PF04032.16 EEB07462.1 - 2.3e-13 50.2 2.6 4.7e-13 49.2 2.6 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.14 EEB07462.1 - 0.0032 17.8 0.1 0.25 11.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27e PF01667.17 EEB07462.1 - 0.15 11.8 0.9 8.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 DUF866 PF05907.13 EEB07462.1 - 0.23 11.4 1.3 1.7 8.6 1.2 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) DUF4674 PF15719.5 EEB07462.1 - 0.34 10.9 7.1 17 5.4 5.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) DUF1178 PF06676.11 EEB07462.1 - 1.5 9.2 4.2 6 7.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) DUF155 PF02582.14 EEB07463.1 - 2.1e-48 164.7 0.9 3e-48 164.3 0.9 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PEPcase PF00311.17 EEB07464.1 - 0.042 11.9 1.9 0.047 11.8 1.9 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Neurochondrin PF05536.11 EEB07465.1 - 5.3e-22 77.9 4.1 8.3e-13 47.6 0.2 2.2 2 1 0 2 2 2 2 Neurochondrin Rotamase PF00639.21 EEB07466.1 - 4.4e-25 88.5 0.0 5.8e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EEB07466.1 - 1.5e-20 73.8 0.0 1.9e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EEB07466.1 - 5.4e-09 36.0 1.8 1.1e-08 35.0 0.7 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EEB07466.1 - 2.1e-06 28.6 0.0 3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 EEB07466.1 - 0.054 14.2 0.0 0.099 13.3 0.0 1.4 1 0 0 1 1 1 0 X8 domain RNase_P_pop3 PF08228.11 EEB07467.1 - 1.4e-19 70.7 0.0 1.8e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 RRM_1 PF00076.22 EEB07468.1 - 4.2e-19 68.1 0.0 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.14 EEB07469.1 - 5.2e-147 490.1 19.9 6.2e-147 489.9 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEB07469.1 - 0.66 9.0 13.0 0.18 10.9 1.5 3.0 2 2 0 2 2 2 0 Glycosyl Hydrolase Family 88 Yippee-Mis18 PF03226.14 EEB07470.2 - 3e-25 88.5 0.5 5.8e-25 87.5 0.5 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EEB07470.2 - 0.0079 16.4 0.2 0.015 15.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of RIG-I ERCC4 PF02732.15 EEB07471.2 - 7.3e-20 71.7 0.0 1.8e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Cupin_1 PF00190.22 EEB07471.2 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Cupin MtrB PF05440.12 EEB07471.2 - 0.14 12.6 0.0 0.49 10.8 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B HMG_box PF00505.19 EEB07472.1 - 1.1e-12 48.2 10.5 5.4e-12 45.9 1.8 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EEB07472.1 - 4.7e-11 43.1 6.9 2.6e-10 40.7 0.7 3.3 2 2 1 3 3 3 1 HMG-box domain Casc1 PF12366.8 EEB07472.1 - 0.0026 17.3 0.9 0.0026 17.3 0.9 2.2 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 Z1 PF10593.9 EEB07472.1 - 1.6 8.2 7.7 0.62 9.5 1.7 2.2 2 0 0 2 2 2 0 Z1 domain HAUS6_N PF14661.6 EEB07472.1 - 6.7 6.2 9.9 1.1 8.9 2.1 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DEAD PF00270.29 EEB07473.1 - 1.8e-51 174.4 0.0 3.3e-50 170.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07473.1 - 1.2e-25 90.0 0.0 4.5e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07473.1 - 0.0023 18.0 0.0 0.0097 15.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Oxidored-like PF09791.9 EEB07474.1 - 4.2e-19 67.9 2.5 6.5e-19 67.3 2.5 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DnaJ PF00226.31 EEB07475.1 - 7.8e-23 80.4 1.1 7.8e-23 80.4 1.1 2.4 3 0 0 3 3 3 1 DnaJ domain RRM_1 PF00076.22 EEB07475.1 - 0.00095 18.9 0.0 0.0032 17.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EEB07476.1 - 2.9e-08 34.2 9.9 0.045 14.6 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat WSC PF01822.19 EEB07476.1 - 0.74 10.0 3.5 0.77 10.0 0.7 2.3 2 0 0 2 2 2 0 WSC domain Proteasome PF00227.26 EEB07477.2 - 1.1e-46 158.8 0.1 1.4e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB07477.2 - 5.8e-14 51.4 0.1 9.3e-14 50.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1823 PF08853.11 EEB07477.2 - 0.17 12.1 0.0 0.47 10.7 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1823) Rad17 PF03215.15 EEB07478.1 - 1.6e-38 132.5 0.0 3.1e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EEB07478.1 - 6.6e-06 26.6 0.0 2.6e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEB07478.1 - 3.3e-05 24.3 0.0 9.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EEB07478.1 - 7.7e-05 23.0 0.0 0.0016 18.8 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EEB07478.1 - 0.00021 21.6 0.0 0.0013 19.0 0.0 2.2 2 1 0 3 3 2 1 AAA domain ABC_tran PF00005.27 EEB07478.1 - 0.0011 19.4 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 EEB07478.1 - 0.0012 18.0 0.0 0.084 11.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EEB07478.1 - 0.0027 17.6 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 EEB07478.1 - 0.0043 16.8 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEB07478.1 - 0.0049 17.0 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEB07478.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EEB07478.1 - 0.016 15.7 0.0 0.06 13.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 EEB07478.1 - 0.018 14.7 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 EEB07478.1 - 0.033 13.9 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EEB07478.1 - 0.053 13.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 EEB07478.1 - 0.058 12.9 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EEB07478.1 - 0.092 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEB07478.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEB07478.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEB07478.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EEB07479.2 - 1e-71 241.0 0.0 1.5e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EEB07479.2 - 6.3e-47 159.0 0.0 1.1e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EEB07479.2 - 8.8e-17 61.4 1.0 4.6e-16 59.1 1.0 2.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DPPIV_N PF00930.21 EEB07480.1 - 1.3e-51 175.5 0.3 1.8e-51 175.0 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EEB07480.1 - 7.2e-24 84.4 0.1 1.3e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EEB07480.1 - 3.8e-06 26.7 0.1 1.2e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EEB07480.1 - 0.0036 17.9 0.0 0.019 15.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EEB07480.1 - 4.4 6.8 5.4 2 8.0 0.1 2.9 3 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) SH3_1 PF00018.28 EEB07481.1 - 2.1e-27 94.4 1.7 2.3e-13 49.5 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EEB07481.1 - 4.1e-26 90.6 2.5 2.8e-13 49.5 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EEB07481.1 - 3.5e-19 68.2 0.1 1.8e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EEB07481.1 - 9.1e-19 67.4 0.0 1.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NIF PF03031.18 EEB07482.2 - 5.4e-20 71.7 0.1 7e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Zn_clus PF00172.18 EEB07484.2 - 3.1e-07 30.4 9.8 4.9e-07 29.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nas2_N PF18265.1 EEB07485.1 - 6e-27 93.4 0.9 8.3e-27 92.9 0.9 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EEB07485.1 - 0.00068 19.4 0.2 0.0019 18.0 0.2 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EEB07485.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EEB07485.1 - 0.042 14.2 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.14 EEB07485.1 - 0.045 14.1 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CCDC85 PF10226.9 EEB07485.1 - 0.051 13.3 0.7 7.1 6.3 0.3 2.4 2 0 0 2 2 2 0 CCDC85 family Sec2p PF06428.11 EEB07485.1 - 0.25 11.3 3.7 13 5.8 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SNF2_N PF00176.23 EEB07486.1 - 2.1e-61 207.6 0.2 3.8e-61 206.7 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB07486.1 - 2.4e-18 66.5 0.0 3.4e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07486.1 - 1.9e-13 50.8 0.0 5.7e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 EEB07486.1 - 1.1e-10 41.6 2.1 1.1e-10 41.6 2.1 4.2 3 1 1 4 4 4 1 HSA DEAD PF00270.29 EEB07486.1 - 5.7e-05 23.0 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Membr_traf_MHD PF10540.9 EEB07487.2 - 2.7e-22 79.5 3.7 7e-20 71.7 0.5 3.3 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EEB07487.2 - 1.1e-08 35.2 0.0 3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain RE_AlwI PF09491.10 EEB07487.2 - 0.018 13.8 2.0 3.8 6.2 0.1 2.8 2 1 0 2 2 2 0 AlwI restriction endonuclease CREPT PF16566.5 EEB07487.2 - 7.4 6.7 6.7 6.9 6.8 0.2 3.8 5 0 0 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour RRM_1 PF00076.22 EEB07488.1 - 2.6e-38 129.7 0.0 9.8e-15 54.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB07488.1 - 5.4e-07 29.5 0.0 0.00085 19.3 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EEB07488.1 - 0.00018 21.1 0.0 0.21 11.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB07488.1 - 0.03 14.4 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif SNF2_N PF00176.23 EEB07489.1 - 1.9e-66 224.2 0.1 3.5e-66 223.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB07489.1 - 1.3e-21 77.0 0.1 1.9e-20 73.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07489.1 - 2.5e-06 27.6 0.0 5.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEB07489.1 - 8.8e-05 21.8 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CCDC50_N PF15295.6 EEB07489.1 - 0.0098 16.0 1.9 0.032 14.4 1.9 1.9 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus Tudor-knot PF11717.8 EEB07489.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain 14-3-3 PF00244.20 EEB07490.1 - 8.3e-106 352.5 5.4 9.6e-106 352.3 5.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4710 PF15828.5 EEB07490.1 - 0.023 14.8 2.8 0.22 11.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4710) CofC PF01983.16 EEB07490.1 - 0.038 13.2 0.8 0.057 12.6 0.8 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like Ku_PK_bind PF08785.11 EEB07490.1 - 0.11 12.7 1.5 1.4 9.1 0.1 2.7 2 1 1 3 3 3 0 Ku C terminal domain like SIKE PF05769.11 EEB07490.1 - 0.39 10.6 6.2 0.75 9.7 0.4 2.8 3 0 0 3 3 3 0 SIKE family MCM6_C PF18263.1 EEB07490.1 - 2.1 8.6 10.7 1.2 9.4 0.9 3.0 2 1 1 3 3 3 0 MCM6 C-terminal winged-helix domain PPR_2 PF13041.6 EEB07491.1 - 0.0073 16.5 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family CorA PF01544.18 EEB07492.1 - 9.3e-50 169.6 0.0 1.4e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.28 EEB07493.1 - 5.5e-13 49.9 8.7 5.5e-13 49.9 8.7 2.0 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase RTA1 PF04479.13 EEB07494.1 - 1.2e-58 198.2 7.2 1.8e-58 197.5 7.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Metallophos PF00149.28 EEB07495.1 - 1.5e-14 55.0 5.3 2.5e-14 54.3 4.7 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EEB07495.1 - 0.0099 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Prenyltrans PF00432.21 EEB07496.1 - 3.8e-33 112.9 19.1 8.1e-09 35.1 0.7 6.0 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat BRO1 PF03097.18 EEB07497.1 - 4.2e-86 289.2 1.0 7.5e-86 288.4 1.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEB07497.1 - 6.1e-38 130.8 12.4 6.1e-38 130.8 12.4 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF2605 PF10792.9 EEB07497.1 - 0.026 14.4 1.0 1.3 8.9 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) YkyA PF10368.9 EEB07497.1 - 0.031 13.9 5.0 0.16 11.6 0.2 3.6 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DUF870 PF05912.11 EEB07497.1 - 0.16 12.0 0.2 0.77 9.8 0.1 2.1 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) Mst1_SARAH PF11629.8 EEB07497.1 - 0.18 11.9 3.3 0.21 11.7 0.8 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF445 PF04286.12 EEB07497.1 - 1.6 8.5 12.9 25 4.5 12.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Ribosomal_S24e PF01282.19 EEB07498.1 - 5.7e-33 112.7 0.2 1.1e-32 111.8 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein S24e RRXRR PF14239.6 EEB07498.1 - 0.0057 16.5 3.8 0.0062 16.4 3.5 1.3 1 1 0 1 1 1 1 RRXRR protein Use1 PF09753.9 EEB07499.1 - 2e-14 53.9 9.1 2.1e-14 53.9 9.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Exonuc_VII_L PF02601.15 EEB07499.1 - 0.12 11.9 7.8 0.15 11.6 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2043 PF09740.9 EEB07499.1 - 0.2 12.3 3.3 0.2 12.3 0.8 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) Ctr PF04145.15 EEB07499.1 - 0.73 10.5 4.2 1.2 9.7 4.2 1.4 1 1 0 1 1 1 0 Ctr copper transporter family MnmE_helical PF12631.7 EEB07499.1 - 2.9 8.0 7.6 2.8 8.1 5.4 2.2 2 1 0 2 2 2 0 MnmE helical domain FYVE PF01363.21 EEB07500.1 - 2.6e-22 78.7 27.2 1.5e-12 47.4 10.1 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EEB07500.1 - 1.6e-13 50.1 1.3 4.2e-13 48.8 1.3 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EEB07500.1 - 2.1e-05 24.6 5.4 2.1e-05 24.6 5.4 4.2 4 1 0 4 4 4 1 AN1-like Zinc finger IBR PF01485.21 EEB07500.1 - 0.0029 17.8 1.3 0.0029 17.8 1.3 3.7 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EEB07500.1 - 0.018 15.4 0.9 0.018 15.4 0.9 3.3 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain AAA_23 PF13476.6 EEB07500.1 - 0.041 14.4 3.6 39 4.7 8.1 2.5 2 2 0 2 2 2 0 AAA domain PHD_3 PF13922.6 EEB07500.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf-C2H2_2 PF12756.7 EEB07500.1 - 0.22 11.9 0.2 0.22 11.9 0.2 3.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Trm112p PF03966.16 EEB07500.1 - 0.8 10.3 9.5 29 5.3 0.1 3.1 2 2 0 2 2 2 0 Trm112p-like protein Sec62 PF03839.16 EEB07501.1 - 1.5e-54 184.8 1.8 2.5e-54 184.1 1.8 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 OPT PF03169.15 EEB07501.1 - 0.0032 16.2 1.3 0.0042 15.8 1.3 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FixQ PF05545.11 EEB07501.1 - 0.039 13.9 1.1 0.039 13.9 1.1 2.6 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DEP PF00610.21 EEB07501.1 - 0.059 13.4 0.4 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PMAIP1 PF15150.6 EEB07501.1 - 0.77 9.7 2.7 2.3 8.1 0.5 2.3 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Imm17 PF15562.6 EEB07501.1 - 1.1 9.1 9.0 1.7 8.6 9.0 1.3 1 0 0 1 1 1 0 Immunity protein 17 SWIRM PF04433.17 EEB07502.1 - 5.4e-30 103.6 0.0 1.5e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EEB07502.1 - 1.4e-10 41.2 0.1 3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EEB07502.1 - 2.4e-10 40.2 12.9 2.4e-10 40.2 12.9 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 EEB07502.1 - 4e-06 27.0 0.1 1.4e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EEB07502.1 - 0.14 12.0 0.8 0.27 11.1 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type SKN1 PF03935.15 EEB07503.1 - 3.4e-221 735.0 2.9 4.2e-221 734.7 2.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cullin PF00888.22 EEB07504.2 - 2.5e-175 584.7 12.6 3.1e-175 584.3 12.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEB07504.2 - 6e-26 90.3 6.3 1.9e-25 88.6 3.8 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.25 EEB07505.1 - 1.1e-68 231.5 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07505.1 - 3.2e-32 111.9 0.0 4.3e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB07505.1 - 9.8e-06 24.7 0.1 1.3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEB07505.1 - 0.00022 20.6 0.1 0.00073 18.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEB07505.1 - 0.00052 19.4 0.0 0.13 11.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EEB07505.1 - 0.00086 19.3 0.1 0.0026 17.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEB07505.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEB07505.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Hydrolase PF00702.26 EEB07506.2 - 7.8e-12 45.9 0.0 3.8e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB07506.2 - 5.4e-11 42.9 0.0 8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEB07506.2 - 0.00018 21.5 0.2 0.00068 19.6 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EEB07506.2 - 0.0063 16.9 0.1 0.0088 16.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EEB07506.2 - 0.013 15.3 0.1 0.034 13.9 0.1 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 EEB07506.2 - 0.036 13.9 0.0 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Arb1 PF09692.10 EEB07507.2 - 1.4e-70 238.6 0.0 3.6e-70 237.2 0.0 1.6 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RHD3 PF05879.12 EEB07508.1 - 6.5e-228 758.6 14.2 9.6e-228 758.0 14.2 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EEB07508.1 - 8.9e-08 31.7 0.6 8.9e-08 31.7 0.6 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EEB07508.1 - 1.2e-06 28.6 0.1 4.6e-06 26.7 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEB07508.1 - 1e-05 25.7 0.1 3.4e-05 24.0 0.1 2.0 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EEB07508.1 - 0.00044 20.5 2.5 0.041 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEB07508.1 - 0.037 14.5 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RecT PF03837.14 EEB07508.1 - 0.054 13.0 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 RecT family Roc PF08477.13 EEB07508.1 - 0.079 13.2 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EEB07508.1 - 0.098 12.5 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 EEB07508.1 - 0.13 11.8 0.7 0.43 10.1 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B Ras PF00071.22 EEB07508.1 - 0.14 11.8 2.0 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 Ras family 6PF2K PF01591.18 EEB07509.1 - 1.4e-72 243.6 0.5 2.2e-72 243.0 0.5 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEB07509.1 - 1e-19 71.0 0.0 1.4e-17 64.1 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEB07509.1 - 0.00015 21.9 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEB07509.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EEB07509.1 - 0.095 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MreC PF04085.14 EEB07509.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 rod shape-determining protein MreC Ribosomal_L18 PF17135.4 EEB07510.1 - 1.6e-89 298.3 5.9 1.8e-89 298.1 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EEB07510.1 - 0.0002 22.0 0.1 0.0002 22.0 0.1 2.5 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pput2613-deam PF14427.6 EEB07510.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase DUF4276 PF14103.6 EEB07510.1 - 0.14 12.3 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) ATP-synt_ab PF00006.25 EEB07511.1 - 5.3e-63 212.5 0.0 7.7e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EEB07511.1 - 4.1e-22 78.5 0.3 8.5e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EEB07511.1 - 0.0014 18.0 0.2 0.0031 16.9 0.2 1.6 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EEB07511.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EEB07511.1 - 0.035 14.0 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EEB07511.1 - 0.037 13.9 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EEB07511.1 - 0.046 14.1 0.0 0.83 10.1 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EEB07511.1 - 0.05 12.8 0.4 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain T3SS_ATPase_C PF18269.1 EEB07511.1 - 0.055 13.3 0.5 0.28 11.1 0.5 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 EEB07511.1 - 0.06 13.7 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EEB07511.1 - 0.072 13.4 1.1 0.48 10.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain EAL PF00563.20 EEB07511.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 EAL domain AAA_16 PF13191.6 EEB07511.1 - 0.19 12.1 0.4 0.78 10.1 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Pyr_redox_2 PF07992.14 EEB07512.2 - 1.5e-10 40.8 0.0 1.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB07512.2 - 1.4e-05 24.5 0.1 0.73 9.0 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEB07512.2 - 0.0082 15.8 0.1 0.8 9.2 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Malic_M PF03949.15 EEB07512.2 - 0.051 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Cupin_2 PF07883.11 EEB07512.2 - 0.13 12.0 0.1 6.7 6.5 0.0 2.7 2 1 0 2 2 2 0 Cupin domain RNA_pol_Rbc25 PF08292.12 EEB07513.1 - 1.1e-40 138.8 0.0 1.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EEB07513.1 - 1.3e-16 60.7 0.0 2.5e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EEB07513.1 - 0.00066 20.0 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain GTP_EFTU PF00009.27 EEB07514.2 - 1.6e-41 142.0 0.0 5.3e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EEB07514.2 - 2.4e-15 56.6 5.6 4.9e-15 55.6 5.6 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EEB07514.2 - 1.8e-06 28.0 0.0 0.071 13.2 0.0 3.6 2 1 1 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EEB07514.2 - 3.5e-06 27.3 0.1 5.2e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EEB07514.2 - 9.9e-05 22.6 0.1 0.00025 21.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain DUF87 PF01935.17 EEB07514.2 - 3 7.9 7.7 1.9 8.5 3.7 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_membrane PF00664.23 EEB07515.1 - 9.6e-67 225.5 45.5 1e-36 127.0 19.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEB07515.1 - 4e-61 205.5 0.0 9.7e-30 103.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEB07515.1 - 1.4e-14 54.1 5.7 7.8e-05 22.2 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEB07515.1 - 2e-09 37.7 7.3 0.0011 18.8 0.2 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EEB07515.1 - 3.3e-09 36.1 0.2 0.0034 16.2 0.0 3.9 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EEB07515.1 - 8.5e-09 35.0 0.9 0.0025 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EEB07515.1 - 1.5e-07 32.0 0.0 0.0055 17.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEB07515.1 - 4e-07 30.6 0.1 0.013 15.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EEB07515.1 - 1.6e-06 28.5 3.2 0.048 13.9 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EEB07515.1 - 0.00013 22.2 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EEB07515.1 - 0.00024 20.9 0.1 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 EEB07515.1 - 0.00025 21.1 0.5 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 EEB07515.1 - 0.00027 21.5 0.6 0.13 12.7 0.2 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEB07515.1 - 0.00035 20.5 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Mg_chelatase PF01078.21 EEB07515.1 - 0.0016 17.9 0.0 0.57 9.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EEB07515.1 - 0.0033 17.6 0.3 1.2 9.4 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EEB07515.1 - 0.0033 17.8 0.1 14 6.1 0.0 3.7 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 EEB07515.1 - 0.0044 17.0 2.9 1.8 8.4 0.0 3.6 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.6 EEB07515.1 - 0.005 16.4 0.2 1.5 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EEB07515.1 - 0.0076 15.6 1.7 2.1 7.6 0.0 3.0 3 1 1 4 4 3 1 FtsK/SpoIIIE family APS_kinase PF01583.20 EEB07515.1 - 0.008 16.1 2.2 1.3 8.9 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EEB07515.1 - 0.0081 15.5 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EEB07515.1 - 0.0085 15.8 1.2 3.1 7.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEB07515.1 - 0.013 15.5 0.0 7.6 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 EEB07515.1 - 0.022 14.5 0.0 7.1 6.3 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 EEB07515.1 - 0.061 12.8 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 EEB07515.1 - 0.14 11.8 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 EEB07515.1 - 0.15 11.8 0.5 11 5.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EEB07515.1 - 0.2 10.6 0.2 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) IstB_IS21 PF01695.17 EEB07515.1 - 0.25 11.1 4.7 5.8 6.6 0.0 4.1 6 0 0 6 6 3 0 IstB-like ATP binding protein DUF87 PF01935.17 EEB07515.1 - 1.3 9.1 8.1 6.1 6.9 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain NB-ARC PF00931.22 EEB07515.1 - 3.3 6.8 5.1 28 3.8 0.4 2.8 2 1 0 2 2 2 0 NB-ARC domain zf-C3HC4_3 PF13920.6 EEB07516.1 - 0.7 9.8 8.6 0.27 11.1 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1_C PF08438.10 EEB07517.1 - 1.1e-32 112.9 0.0 1.8e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EEB07517.1 - 1e-20 73.9 0.0 2.8e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB07517.1 - 4.6e-07 29.5 0.1 6.5e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEB07517.1 - 0.0021 18.2 0.5 0.0059 16.7 0.0 2.0 3 0 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 EEB07517.1 - 0.0029 17.5 0.5 1.6 8.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEB07517.1 - 0.0083 15.7 0.2 1.5 8.3 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EEB07517.1 - 0.0093 15.8 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 EEB07517.1 - 0.035 14.0 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 EEB07517.1 - 0.037 13.0 0.1 0.072 12.1 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 EEB07517.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EEB07517.1 - 0.14 12.7 0.8 0.51 10.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EEB07517.1 - 0.24 11.2 1.1 0.47 10.2 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.22 EEB07518.1 - 1.7e-48 164.3 0.6 2e-48 164.1 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB07518.1 - 4.4e-16 59.2 0.1 6.1e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB07518.1 - 1.6e-07 31.0 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB07518.1 - 1.4e-06 28.0 0.1 1.8e-05 24.3 0.1 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEB07518.1 - 2.7e-05 23.7 0.1 3.2e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEB07518.1 - 0.00032 20.7 0.1 0.00044 20.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB07518.1 - 0.0021 18.0 0.2 0.41 10.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 EEB07518.1 - 0.011 15.8 0.1 0.013 15.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EEB07518.1 - 0.024 14.1 0.1 0.13 11.8 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EEB07518.1 - 0.049 13.5 1.7 0.1 12.5 1.7 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea WAPL PF07814.13 EEB07519.1 - 4e-13 48.9 5.3 4e-13 48.9 5.3 2.6 2 1 0 3 3 3 2 Wings apart-like protein regulation of heterochromatin tRNA_NucTran2_2 PF13735.6 EEB07519.1 - 0.021 14.8 0.3 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative CDT1_C PF16679.5 EEB07520.1 - 1.2e-15 57.7 0.5 4.4e-15 55.9 0.2 2.2 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain CDT1 PF08839.11 EEB07520.1 - 2.8e-08 34.3 3.8 3.6e-07 30.6 2.5 3.2 2 1 0 2 2 2 1 DNA replication factor CDT1 like DUF5633 PF18656.1 EEB07520.1 - 0.013 15.4 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5633) UTP15_C PF09384.10 EEB07521.1 - 1.7e-46 157.6 0.0 5e-46 156.0 0.1 1.8 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 EEB07521.1 - 5.3e-23 80.9 11.4 3.3e-06 27.7 0.5 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07521.1 - 1e-09 38.6 1.1 0.003 17.8 0.1 4.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EEB07521.1 - 0.0026 16.7 1.2 0.18 10.7 0.1 2.4 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EEB07521.1 - 0.094 12.0 0.0 0.39 10.0 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Utp8 PF10395.9 EEB07521.1 - 0.18 10.2 0.1 4.5 5.7 0.1 2.4 3 0 0 3 3 3 0 Utp8 family GCP_C_terminal PF04130.13 EEB07522.2 - 1.7e-83 280.6 7.0 3e-83 279.8 7.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EEB07522.2 - 1.8e-67 228.1 0.2 1.8e-67 228.1 0.2 1.9 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal FANCI_S3 PF14677.6 EEB07522.2 - 0.01 15.6 0.7 0.033 13.9 0.1 2.3 2 0 0 2 2 2 1 FANCI solenoid 3 AAA PF00004.29 EEB07523.1 - 1.9e-11 44.5 0.0 4.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEB07523.1 - 1.1e-07 32.0 0.0 3.8e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 EEB07523.1 - 4e-07 30.1 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EEB07523.1 - 8.5e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEB07523.1 - 2.1e-06 28.0 0.0 7.9e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB07523.1 - 6e-06 26.8 0.0 3.3e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EEB07523.1 - 1.4e-05 25.3 0.0 3.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEB07523.1 - 6e-05 22.9 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EEB07523.1 - 0.00013 21.7 0.0 0.00035 20.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEB07523.1 - 0.00015 22.3 0.0 0.00061 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EEB07523.1 - 0.00017 21.3 0.1 0.00034 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEB07523.1 - 0.00029 20.5 0.1 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EEB07523.1 - 0.00046 19.5 0.0 0.00088 18.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EEB07523.1 - 0.0027 18.1 0.0 0.0071 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEB07523.1 - 0.0032 17.7 0.0 0.0084 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EEB07523.1 - 0.0039 17.3 0.2 0.036 14.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.15 EEB07523.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 EEB07523.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EEB07523.1 - 0.0065 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEB07523.1 - 0.0092 16.5 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EEB07523.1 - 0.0097 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 EEB07523.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EEB07523.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 EEB07523.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 EEB07523.1 - 0.021 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 EEB07523.1 - 0.023 14.6 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase cobW PF02492.19 EEB07523.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EEB07523.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB07523.1 - 0.038 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EEB07523.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEB07523.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EEB07523.1 - 0.046 12.8 0.1 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EEB07523.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EEB07523.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_assoc_2 PF16193.5 EEB07523.1 - 0.088 13.2 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_3 PF07726.11 EEB07523.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EEB07523.1 - 0.11 13.0 0.6 0.59 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Polyoma_lg_T_C PF06431.11 EEB07523.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_8 PF12780.7 EEB07523.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Ribosomal_L3 PF00297.22 EEB07524.2 - 6.2e-292 966.5 23.7 1e-166 554.5 8.3 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 Big_3_3 PF13750.6 EEB07524.2 - 0.00029 20.5 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) Pyr_excise PF03013.14 EEB07524.2 - 0.0046 16.9 3.1 0.46 10.5 0.4 2.5 2 0 0 2 2 2 2 Pyrimidine dimer DNA glycosylase RE_TaqI PF09573.10 EEB07524.2 - 0.007 16.2 3.0 1.1 9.0 0.2 2.4 2 0 0 2 2 2 2 TaqI restriction endonuclease REPA_OB_2 PF16900.5 EEB07524.2 - 0.0072 16.2 0.9 5.3 7.0 0.1 2.7 2 0 0 2 2 2 2 Replication protein A OB domain AAA_24 PF13479.6 EEB07524.2 - 0.0081 15.9 7.2 0.63 9.7 1.1 2.2 2 0 0 2 2 2 2 AAA domain ACT_5 PF13710.6 EEB07524.2 - 0.011 15.5 0.8 6.4 6.7 0.1 2.7 2 0 0 2 2 2 0 ACT domain DUF3053 PF11254.8 EEB07524.2 - 0.019 14.5 4.0 2.2 7.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Tho1_MOS11_C PF18592.1 EEB07524.2 - 0.022 14.6 6.7 2.1 8.2 0.4 3.0 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain DUF2797 PF10977.8 EEB07524.2 - 0.023 14.6 0.4 8.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) ZapD PF07072.11 EEB07524.2 - 0.14 11.9 0.3 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Cell division protein DUF3067 PF11267.8 EEB07524.2 - 0.16 12.5 2.2 18 6.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) FadA PF09403.10 EEB07524.2 - 0.54 10.8 8.1 4.4 7.8 2.0 2.5 2 0 0 2 2 2 0 Adhesion protein FadA DUF829 PF05705.14 EEB07524.2 - 1 9.2 3.8 19 5.0 0.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) ABC_tran_Xtn PF12848.7 EEB07524.2 - 2.5 8.2 11.4 8.2 6.5 2.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF2456 PF10445.9 EEB07525.1 - 1.9e-27 95.2 4.2 1.9e-27 95.2 4.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) Apq12 PF12716.7 EEB07525.1 - 0.12 12.3 5.5 0.31 11.0 5.5 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF1769 PF08588.10 EEB07526.1 - 6.5e-18 64.7 0.1 1.3e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) tRNA-synt_2d PF01409.20 EEB07527.1 - 2e-45 155.2 0.1 2.1e-25 89.6 0.0 2.2 1 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EEB07527.1 - 3.9e-21 75.3 0.0 1.5e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DUF2439 PF10382.9 EEB07528.2 - 4.4e-24 84.6 0.2 7.9e-24 83.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) CN_hydrolase PF00795.22 EEB07530.1 - 1.5e-38 132.6 0.0 2.2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EEB07530.1 - 2.6e-21 75.9 0.0 5.9e-21 74.7 0.0 1.5 1 1 0 1 1 1 1 NAD synthase AAA PF00004.29 EEB07531.1 - 1.6e-53 180.6 0.0 2.2e-39 134.9 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EEB07531.1 - 1.1e-19 70.6 0.7 3.2e-19 69.1 0.7 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 EEB07531.1 - 1.4e-12 48.3 1.2 0.004 17.6 0.0 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_25 PF13481.6 EEB07531.1 - 4.2e-08 33.0 0.2 0.66 9.5 0.0 5.8 5 2 1 6 6 5 2 AAA domain AAA_22 PF13401.6 EEB07531.1 - 5.5e-08 33.2 0.8 0.0031 17.8 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EEB07531.1 - 8.4e-08 31.9 0.0 0.00046 19.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_3 PF17862.1 EEB07531.1 - 4.2e-07 29.7 0.0 1.7e-06 27.7 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EEB07531.1 - 6.6e-06 26.0 0.0 0.049 13.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 EEB07531.1 - 1e-05 25.6 0.0 0.2 11.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TsaE PF02367.17 EEB07531.1 - 1.2e-05 25.3 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EEB07531.1 - 1.8e-05 24.7 0.3 0.025 14.5 0.1 3.1 2 1 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.26 EEB07531.1 - 1.8e-05 24.5 0.0 0.047 13.4 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 EEB07531.1 - 2.5e-05 24.3 0.1 0.0084 16.0 0.0 3.2 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EEB07531.1 - 2.6e-05 24.3 0.0 0.15 12.1 0.0 3.0 2 1 1 3 3 2 2 AAA domain RNA_helicase PF00910.22 EEB07531.1 - 2.8e-05 24.5 0.0 0.15 12.5 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 EEB07531.1 - 0.00015 21.9 0.0 0.75 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEB07531.1 - 0.00016 21.5 0.0 0.13 12.0 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEB07531.1 - 0.00031 20.9 0.0 0.66 10.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 EEB07531.1 - 0.00038 20.5 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EEB07531.1 - 0.00048 19.4 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 EEB07531.1 - 0.00072 19.3 0.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEB07531.1 - 0.00086 19.8 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EEB07531.1 - 0.0014 18.0 0.0 0.38 10.1 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EEB07531.1 - 0.0015 17.8 0.0 0.044 12.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EEB07531.1 - 0.0018 18.8 0.0 1.7 9.2 0.0 2.9 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.16 EEB07531.1 - 0.0025 17.3 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Kinesin PF00225.23 EEB07531.1 - 0.0032 16.5 0.0 1 8.2 0.0 2.4 2 1 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.14 EEB07531.1 - 0.0039 16.4 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase TIP49 PF06068.13 EEB07531.1 - 0.0039 16.4 0.0 0.23 10.6 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain ATPase PF06745.13 EEB07531.1 - 0.0048 16.3 0.2 2.2 7.6 0.0 2.7 3 0 0 3 3 2 1 KaiC AAA_30 PF13604.6 EEB07531.1 - 0.006 16.3 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EEB07531.1 - 0.0066 16.6 0.0 3.3 7.8 0.0 3.1 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 EEB07531.1 - 0.01 15.1 0.1 3.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EEB07531.1 - 0.013 14.6 0.0 0.063 12.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF853 PF05872.12 EEB07531.1 - 0.014 14.1 0.0 0.024 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_3 PF07726.11 EEB07531.1 - 0.018 14.9 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EEB07531.1 - 0.027 13.5 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Microtub_bd PF16796.5 EEB07531.1 - 0.027 14.4 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding Zeta_toxin PF06414.12 EEB07531.1 - 0.031 13.6 0.0 4.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 EEB07531.1 - 0.07 13.5 0.0 5.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EEB07531.1 - 0.092 12.5 0.0 5.5 6.7 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EEB07531.1 - 0.093 12.6 0.0 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 EEB07531.1 - 0.1 13.0 0.0 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EEB07531.1 - 0.11 11.9 0.0 5.7 6.3 0.0 3.2 4 0 0 4 4 3 0 Bacterial TniB protein TrwB_AAD_bind PF10412.9 EEB07531.1 - 0.12 11.3 0.0 0.35 9.7 0.0 1.8 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 EEB07531.1 - 0.12 12.1 0.0 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EEB07531.1 - 0.14 12.4 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Caskin-tail PF16632.5 EEB07531.1 - 0.19 12.2 1.1 40 4.7 0.1 3.6 3 0 0 3 3 3 0 C-terminal region of Caskin Pro_isomerase PF00160.21 EEB07532.2 - 2.2e-49 167.7 0.0 4.2e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EEB07532.2 - 2.1e-06 28.3 0.4 0.17 12.8 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07532.2 - 0.0003 21.0 0.0 0.41 11.0 0.1 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EPSP_synthase PF00275.20 EEB07532.2 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Piwi PF02171.17 EEB07533.1 - 9.6e-98 327.1 0.0 1.3e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 EEB07533.1 - 1.8e-22 79.4 0.0 5.6e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 EEB07533.1 - 1.9e-19 69.1 0.8 3.9e-19 68.1 0.8 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EEB07533.1 - 1.7e-17 64.3 0.0 3.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EEB07533.1 - 1.8e-15 56.9 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EEB07533.1 - 2e-12 47.3 0.0 6.9e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain YTH PF04146.15 EEB07534.2 - 3.9e-17 62.7 0.8 2.5e-16 60.0 0.8 2.1 1 1 0 1 1 1 1 YT521-B-like domain Lipase_GDSL PF00657.22 EEB07534.2 - 0.064 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase adh_short PF00106.25 EEB07535.1 - 5.1e-28 97.9 0.0 8.2e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEB07535.1 - 1.1e-17 64.4 0.0 5.6e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB07535.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEB07535.1 - 0.031 13.7 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEB07535.1 - 0.054 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HEAT PF02985.22 EEB07536.1 - 4.9e-14 51.2 5.2 0.04 14.2 0.9 8.4 8 1 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EEB07536.1 - 7.7e-06 26.2 0.0 1.5 9.2 0.0 5.0 4 1 0 4 4 4 1 HEAT repeats CLASP_N PF12348.8 EEB07536.1 - 4.4e-05 23.2 1.9 0.0013 18.3 0.3 3.4 3 1 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 EEB07536.1 - 0.00086 19.5 0.0 2.1 8.6 0.0 3.6 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EEB07536.1 - 0.002 18.2 0.7 1.5 8.8 0.1 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MPS2 PF17060.5 EEB07536.1 - 0.15 11.3 10.3 0.055 12.7 7.3 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 M11L PF11099.8 EEB07536.1 - 0.2 11.9 0.7 1.3 9.2 0.0 2.6 2 1 1 3 3 3 0 Apoptosis regulator M11L like PCRF PF03462.18 EEB07536.1 - 0.85 9.4 7.7 2 8.3 7.7 1.6 1 0 0 1 1 1 0 PCRF domain PLA2G12 PF06951.11 EEB07536.1 - 1.6 8.6 6.0 0.86 9.5 0.3 2.8 3 0 0 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) HEAT_EZ PF13513.6 EEB07536.1 - 5.3 7.6 6.6 38 4.9 0.0 4.8 6 1 0 6 6 6 0 HEAT-like repeat NYD-SP28_assoc PF14775.6 EEB07536.1 - 6.2 7.0 6.5 5.4 7.2 0.9 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain BLM10_mid PF16507.5 EEB07537.1 - 4.3e-158 527.2 2.4 6.7e-158 526.6 2.4 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EEB07537.1 - 9.9e-24 83.1 0.0 3.8e-23 81.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EEB07537.1 - 0.00064 20.0 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 EEB07537.1 - 0.0096 15.5 0.3 1.4 8.4 0.0 2.8 2 0 0 2 2 2 1 CLASP N terminal Arm PF00514.23 EEB07537.1 - 0.2 11.8 1.5 19 5.5 0.1 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EEB07537.1 - 1.8 9.0 8.0 0.58 10.6 0.2 4.0 5 0 0 5 5 5 0 HEAT repeats HEAT PF02985.22 EEB07537.1 - 6.1 7.4 8.6 12 6.5 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat Pil1 PF13805.6 EEB07538.1 - 4.2e-124 413.3 0.2 6.1e-124 412.8 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3958 PF13125.6 EEB07538.1 - 0.027 14.7 1.4 0.12 12.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DNA_primase_lrg PF04104.14 EEB07539.1 - 4.7e-81 272.1 0.0 6.5e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit LtuB PF17455.2 EEB07539.1 - 0.061 14.0 0.3 0.35 11.5 0.1 2.3 1 1 1 2 2 2 0 Late transcription unit B PCI PF01399.27 EEB07540.2 - 1.2e-07 32.2 0.4 3.9e-06 27.3 0.1 3.4 2 1 0 2 2 2 1 PCI domain DASH_Dam1 PF08653.10 EEB07540.2 - 0.31 10.9 1.0 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 zf-HC5HC2H_2 PF13832.6 EEB07541.1 - 4.1e-26 91.3 20.9 1e-25 90.0 13.0 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEB07541.1 - 2.9e-22 78.7 6.9 2.9e-22 78.7 6.9 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EEB07541.1 - 7.9e-14 50.9 2.7 7.9e-14 50.9 2.7 3.7 4 0 0 4 4 4 1 PHD-finger EPL1 PF10513.9 EEB07541.1 - 2.8e-10 40.8 6.0 4.4e-09 36.9 6.0 2.4 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD PF00628.29 EEB07541.1 - 2.3e-09 37.0 11.1 2.3e-09 37.0 11.1 3.3 4 0 0 4 4 4 1 PHD-finger zf-RING-like PF08746.11 EEB07541.1 - 0.015 15.6 7.7 0.015 15.6 7.7 3.1 2 1 0 2 2 2 0 RING-like domain C1_1 PF00130.22 EEB07541.1 - 0.018 14.9 4.1 0.018 14.9 4.1 3.7 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FerA PF08165.11 EEB07541.1 - 0.089 12.8 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 FerA (NUC095) domain DUF3567 PF12091.8 EEB07541.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) C1_2 PF03107.16 EEB07541.1 - 8.3 6.8 23.7 0.25 11.7 3.9 3.2 3 0 0 3 3 3 0 C1 domain CMD PF02627.20 EEB07542.1 - 1.1e-07 31.8 0.0 2.2e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family zf-rbx1 PF12678.7 EEB07543.2 - 2.5e-10 40.5 3.2 7.2e-10 39.0 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEB07543.2 - 1.1e-09 38.5 8.0 1.5e-08 34.8 8.0 2.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEB07543.2 - 3.2e-07 30.1 0.8 9.2e-07 28.6 0.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB07543.2 - 9.2e-07 28.8 3.4 3e-06 27.1 3.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEB07543.2 - 3.4e-06 26.8 6.7 3.4e-05 23.6 2.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB07543.2 - 3.6e-06 26.8 5.4 2.5e-05 24.1 5.1 2.3 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEB07543.2 - 3.8e-05 23.5 4.4 6.9e-05 22.6 1.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EEB07543.2 - 9.1e-05 22.2 2.9 9.1e-05 22.2 2.9 2.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEB07543.2 - 0.00035 20.1 2.4 0.00041 19.9 0.4 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EEB07543.2 - 0.0034 17.4 4.0 0.015 15.3 4.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC5 PF06221.13 EEB07543.2 - 0.021 14.8 1.2 0.17 11.9 0.2 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_4 PF15227.6 EEB07543.2 - 0.25 11.5 4.1 0.11 12.6 1.0 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EEB07543.2 - 2 8.3 7.3 0.85 9.4 0.1 3.1 4 0 0 4 4 4 0 RING-like zinc finger zf-RING_4 PF14570.6 EEB07543.2 - 2.1 8.2 7.5 0.2 11.5 0.8 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EEB07543.2 - 2.2 8.5 5.9 27 5.1 5.9 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 EEB07543.2 - 8.1 6.2 8.0 2.7 7.7 3.7 2.3 2 0 0 2 2 2 0 P-11 zinc finger Gcd10p PF04189.13 EEB07545.1 - 4.4e-83 278.8 0.0 5.8e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family UPF0242 PF06785.11 EEB07545.1 - 0.014 15.5 1.3 0.026 14.6 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2122 PF09895.9 EEB07545.1 - 0.14 12.6 0.2 0.4 11.1 0.2 1.7 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) LSM14 PF12701.7 EEB07546.1 - 4.4e-30 103.6 0.0 8e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EEB07546.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 EEB07546.1 - 4.3e-06 27.5 3.0 5.9e-05 23.9 0.1 4.2 3 1 1 4 4 4 2 FDF domain DUF5320 PF17253.2 EEB07546.1 - 0.053 14.6 5.4 0.053 14.6 5.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ras PF00071.22 EEB07548.2 - 5.4e-66 221.2 0.4 6.6e-66 220.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB07548.2 - 9.6e-37 125.9 0.1 1.9e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB07548.2 - 2.5e-17 62.9 0.2 3e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EEB07548.2 - 1e-05 25.5 0.2 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEB07548.2 - 1.1e-05 25.1 0.4 2.7e-05 23.8 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEB07548.2 - 1.9e-05 24.2 0.1 3.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEB07548.2 - 2.5e-05 24.3 0.0 6.9e-05 22.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEB07548.2 - 3e-05 23.5 0.1 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EEB07548.2 - 0.0011 19.4 0.0 0.11 12.9 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EEB07548.2 - 0.0021 17.6 0.0 0.02 14.4 0.0 2.3 1 1 1 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 EEB07548.2 - 0.014 15.8 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEB07548.2 - 0.033 14.4 0.0 0.062 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEB07548.2 - 0.038 13.7 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EEB07548.2 - 0.043 13.6 0.1 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EEB07548.2 - 0.043 13.1 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 EEB07548.2 - 0.063 13.3 0.1 0.15 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) LANC_like PF05147.13 EEB07548.2 - 0.064 11.8 0.1 0.21 10.1 0.0 1.7 2 1 0 2 2 2 0 Lanthionine synthetase C-like protein ABC_tran PF00005.27 EEB07548.2 - 0.075 13.6 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EEB07548.2 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EEB07548.2 - 0.085 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein CENP-M PF11111.8 EEB07548.2 - 0.14 11.3 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) OPA3 PF07047.12 EEB07549.1 - 6.2e-45 152.0 0.4 7.9e-45 151.7 0.4 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) ZapA PF05164.13 EEB07549.1 - 0.056 13.9 0.6 0.26 11.8 0.1 2.2 3 0 0 3 3 3 0 Cell division protein ZapA DAP3 PF10236.9 EEB07550.1 - 9.2e-67 225.4 0.1 1.1e-66 225.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.12 EEB07551.1 - 1.2e-51 174.8 0.8 1.3e-51 174.7 0.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.20 EEB07552.1 - 1.7e-23 83.8 1.9 1.1e-22 81.2 0.2 2.5 3 0 0 3 3 3 1 RhoGEF domain RasGEF_N_2 PF14663.6 EEB07552.1 - 0.029 14.7 4.6 0.18 12.2 0.1 3.5 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cytochrom_C1 PF02167.15 EEB07553.1 - 1.1e-87 293.4 0.0 1.4e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EEB07553.1 - 0.00057 20.1 0.0 0.0018 18.6 0.0 1.9 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EEB07553.1 - 0.0025 18.9 0.0 0.19 12.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c PorA PF11271.8 EEB07553.1 - 0.079 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Porin PorA DUF4271 PF14093.6 EEB07553.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Lactonase PF10282.9 EEB07554.1 - 5.5e-61 206.7 0.0 6.6e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 EEB07554.1 - 0.0044 17.0 1.4 0.2 11.8 0.1 3.5 3 0 0 3 3 3 1 NHL repeat Cry1Ac_D5 PF17997.1 EEB07554.1 - 0.17 11.7 1.1 0.58 10.0 0.2 2.0 1 1 1 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 PMI_typeI PF01238.21 EEB07555.1 - 6.8e-118 394.1 0.0 8.5e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Ectoine_synth PF06339.12 EEB07555.1 - 0.094 12.9 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Ectoine synthase SUN PF03856.13 EEB07556.2 - 3e-91 305.3 12.8 3.8e-91 304.9 12.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) WD40 PF00400.32 EEB07557.2 - 1.4e-38 130.2 24.5 3.7e-06 27.6 1.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07557.2 - 1.3e-08 35.0 2.4 2.8 8.3 0.0 6.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EEB07557.2 - 7.7e-08 32.1 1.9 1.7e-07 31.1 1.9 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EEB07557.2 - 1.9e-06 26.8 8.5 0.47 9.0 0.1 5.9 1 1 3 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 EEB07557.2 - 7.3e-06 25.7 0.7 2.2e-05 24.2 0.7 1.8 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EEB07557.2 - 0.0015 18.2 1.1 2.7 7.5 0.0 3.2 2 1 0 3 3 3 2 PQQ-like domain F-box_4 PF15966.5 EEB07557.2 - 0.0034 17.3 0.1 0.0086 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box Frtz PF11768.8 EEB07557.2 - 0.0059 15.0 0.2 0.25 9.6 0.1 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 EEB07557.2 - 0.0063 17.0 0.5 6.3 7.4 0.2 3.8 3 0 0 3 3 3 1 PQQ-like domain DUF5046 PF16465.5 EEB07557.2 - 0.063 12.7 1.9 11 5.3 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF5046) PQQ PF01011.21 EEB07557.2 - 0.074 13.0 1.2 34 4.6 0.0 4.7 5 1 1 6 6 6 0 PQQ enzyme repeat PRANC PF09372.10 EEB07557.2 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 PRANC domain PALB2_WD40 PF16756.5 EEB07557.2 - 0.26 10.2 4.9 15 4.4 0.1 4.0 2 2 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain PHD PF00628.29 EEB07558.1 - 2.8e-05 23.9 11.4 8.5e-05 22.4 11.4 1.8 1 0 0 1 1 1 1 PHD-finger HORMA PF02301.18 EEB07558.1 - 0.0007 19.2 2.1 0.0012 18.5 1.2 1.9 1 1 1 2 2 2 1 HORMA domain PHD_2 PF13831.6 EEB07558.1 - 0.011 15.3 5.3 0.011 15.3 5.3 1.9 2 0 0 2 2 2 0 PHD-finger DUF755 PF05501.11 EEB07559.1 - 0.0031 17.8 4.3 0.004 17.4 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Coilin_N PF15862.5 EEB07559.1 - 0.16 11.7 8.8 0.21 11.4 8.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus CDC45 PF02724.14 EEB07559.1 - 2.9 6.1 10.5 2.7 6.2 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 EEB07559.1 - 7.9 5.3 14.6 9.4 5.0 14.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 EEB07559.1 - 8 5.6 6.7 9.4 5.3 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Acyltransferase PF01553.21 EEB07560.1 - 4.5e-11 42.5 0.0 4.6e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.16 EEB07561.1 - 8.2e-45 152.1 0.0 1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dynamin_N PF00350.23 EEB07562.1 - 5.2e-42 143.7 2.0 2.1e-41 141.8 0.0 2.9 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 EEB07562.1 - 3.8e-11 42.7 0.2 3.8e-11 42.7 0.2 2.6 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 EEB07562.1 - 2.9e-06 27.3 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EEB07562.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_21 PF13304.6 EEB07562.1 - 0.011 15.6 0.1 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EEB07562.1 - 0.017 15.4 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EEB07562.1 - 0.029 14.1 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 EEB07562.1 - 0.062 13.0 0.1 0.062 13.0 0.1 2.7 4 0 0 4 4 4 0 AAA ATPase domain PH PF00169.29 EEB07563.1 - 8.1e-20 71.3 1.5 3.6e-09 37.1 0.3 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EEB07563.1 - 1.7e-05 25.2 6.0 0.039 14.4 0.9 4.2 2 2 1 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 EEB07563.1 - 0.00037 20.7 0.1 0.07 13.4 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 EEB07563.1 - 0.00037 20.6 1.2 0.033 14.3 0.1 2.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 EEB07563.1 - 0.015 15.7 1.2 3.9 7.9 0.0 3.0 2 2 0 2 2 2 0 Pleckstrin homology domain DNApol_Exo PF18136.1 EEB07564.1 - 4.7e-102 340.9 0.1 3.9e-101 337.9 0.0 2.2 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EEB07564.1 - 7.1e-51 173.4 0.0 1.1e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EEB07564.1 - 0.053 13.2 2.0 1.8 8.3 2.0 2.4 1 1 0 1 1 1 0 3'-5' exonuclease SET PF00856.28 EEB07565.1 - 5e-08 33.5 0.2 8.8e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EEB07565.1 - 5.7e-08 32.7 21.7 5.7e-08 32.7 21.7 2.3 2 0 0 2 2 2 1 MYND finger PG_binding_1 PF01471.18 EEB07565.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF3844 PF12955.7 EEB07565.1 - 7.5 6.7 16.4 27 5.0 10.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) LCM PF04072.14 EEB07566.1 - 8.5e-21 74.8 0.0 2.2e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Xpo1 PF08389.12 EEB07567.1 - 4.5e-34 117.7 1.4 1.2e-32 113.0 0.0 3.7 3 1 1 4 4 4 1 Exportin 1-like protein NUC130_3NT PF08158.12 EEB07567.1 - 0.00067 19.9 0.3 9.1 6.7 0.0 4.5 3 0 0 3 3 3 2 NUC130/3NT domain Fanconi_A_N PF15865.5 EEB07567.1 - 1.4 8.3 4.7 7.8 5.8 0.2 3.0 3 0 0 3 3 3 0 Fanconi anaemia group A protein N terminus U3_snoRNA_assoc PF08297.11 EEB07568.1 - 2e-11 44.4 3.4 2e-11 44.4 3.4 2.5 1 1 1 2 2 2 1 U3 snoRNA associated Sipho_Gp157 PF05565.11 EEB07568.1 - 0.014 15.5 5.3 0.022 14.8 5.3 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 DUF572 PF04502.13 EEB07568.1 - 0.014 15.0 13.7 0.018 14.6 13.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CSRNP_N PF16019.5 EEB07568.1 - 0.015 15.2 5.9 0.021 14.8 5.9 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Med11 PF10280.9 EEB07568.1 - 0.08 13.4 5.9 0.14 12.6 5.9 1.4 1 0 0 1 1 1 0 Mediator complex protein Spt5_N PF11942.8 EEB07568.1 - 0.2 12.7 13.4 0.16 13.0 1.1 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF45 PF01863.17 EEB07568.1 - 0.37 10.8 6.7 0.97 9.4 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF2981 PF11200.8 EEB07568.1 - 0.68 9.6 2.8 0.98 9.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) LMBR1 PF04791.16 EEB07568.1 - 2 7.3 2.8 2.2 7.1 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-B_dimeris PF09026.10 EEB07568.1 - 3.2 8.2 10.7 4.5 7.7 5.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain V_ATPase_I PF01496.19 EEB07568.1 - 4.5 5.1 7.7 4.9 4.9 7.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.13 EEB07568.1 - 6.6 5.5 7.7 8.3 5.2 7.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HSP70 PF00012.20 EEB07568.1 - 8.9 4.3 12.3 11 4.0 12.3 1.1 1 0 0 1 1 1 0 Hsp70 protein NTF2 PF02136.20 EEB07569.1 - 3.4e-21 76.0 0.6 2.1e-18 67.0 0.1 2.4 1 1 1 2 2 2 2 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EEB07569.1 - 6.5e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FSA_C PF10479.9 EEB07569.1 - 4.9 5.2 7.1 6.6 4.7 7.1 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CENP-H PF05837.12 EEB07570.1 - 4.3e-12 46.4 1.5 4.3e-12 46.4 1.5 1.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) PilJ PF13675.6 EEB07570.1 - 0.027 14.5 1.4 0.3 11.1 0.3 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vac7 PF12751.7 EEB07571.1 - 2.8e-14 53.4 8.7 2.8e-14 53.4 8.7 1.3 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 Ferlin_C PF16165.5 EEB07571.1 - 0.0074 16.3 0.4 0.0074 16.3 0.4 1.5 2 0 0 2 2 2 1 Ferlin C-terminus LapA_dom PF06305.11 EEB07571.1 - 0.77 9.6 4.4 1.4 8.8 4.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain P5-ATPase PF12409.8 EEB07571.1 - 1.3 9.1 8.3 0.39 10.8 4.4 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF2981 PF11200.8 EEB07571.1 - 5.9 6.5 7.4 0.22 11.2 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) RabGAP-TBC PF00566.18 EEB07572.1 - 2.5e-52 177.7 1.9 4.1e-52 177.0 1.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol_E_B PF04042.16 EEB07573.1 - 2.3e-54 183.9 0.5 3.6e-54 183.3 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EEB07573.1 - 0.032 14.3 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain DWNN PF08783.11 EEB07574.1 - 4.4e-33 113.4 0.2 7.2e-33 112.7 0.2 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EEB07574.1 - 1.2e-10 41.0 4.2 1.2e-10 41.0 4.2 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EEB07574.1 - 0.00052 20.0 0.9 0.00052 20.0 0.9 1.9 2 0 0 2 2 1 1 Zinc knuckle zf-RING_2 PF13639.6 EEB07574.1 - 0.0023 18.2 11.0 0.0023 18.2 11.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB07574.1 - 0.0028 17.5 12.1 0.0028 17.5 12.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEB07574.1 - 0.015 15.1 10.9 0.015 15.1 10.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB07574.1 - 0.019 14.9 11.0 0.019 14.9 11.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-CCHC_3 PF13917.6 EEB07574.1 - 0.037 14.0 0.5 0.037 14.0 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle Siva PF05458.12 EEB07574.1 - 0.041 13.6 5.7 0.074 12.7 5.7 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4 PF00097.25 EEB07574.1 - 0.066 13.1 12.6 0.14 12.1 12.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EEB07574.1 - 0.47 10.3 10.3 1.2 8.9 10.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC_5 PF14787.6 EEB07574.1 - 0.66 9.7 9.5 0.38 10.5 0.3 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-UDP PF14569.6 EEB07574.1 - 1.3 9.2 6.9 7.8 6.7 0.7 2.8 1 1 1 2 2 2 0 Zinc-binding RING-finger SMN PF06003.12 EEB07574.1 - 5 6.3 12.1 0.42 9.8 6.4 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) HypA PF01155.19 EEB07574.1 - 6.9 6.7 10.2 58 3.7 7.7 2.9 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DEAD PF00270.29 EEB07575.2 - 2.6e-50 170.6 0.0 1.3e-49 168.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07575.2 - 3.8e-30 104.5 0.0 1.8e-29 102.3 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07575.2 - 6.4e-06 26.3 0.0 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEB07575.2 - 0.022 14.5 0.0 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 EEB07575.2 - 0.044 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DHHA2 PF02833.14 EEB07575.2 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 DHHA2 domain AAA_19 PF13245.6 EEB07575.2 - 0.11 12.8 0.0 20 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain CRF1 PF10380.9 EEB07576.1 - 1.2e-07 32.0 1.1 3e-07 30.8 1.1 1.7 1 0 0 1 1 1 1 Transcription factor CRF1 BNIP2 PF12496.8 EEB07576.1 - 5.2 7.5 12.2 1.6 9.2 2.5 2.8 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 LRR_9 PF14580.6 EEB07577.1 - 1.3e-12 47.6 13.3 6.2e-07 29.1 3.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 EEB07577.1 - 8.1e-10 38.3 27.4 2.6e-06 27.1 4.8 5.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EEB07577.1 - 1.9e-08 34.5 33.6 0.00022 21.6 1.8 6.3 4 1 4 8 8 8 6 Leucine Rich repeats (2 copies) DUF2009 PF09418.10 EEB07578.1 - 8e-197 654.8 0.1 9.4e-197 654.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Asp_Arg_Hydrox PF05118.15 EEB07578.1 - 0.12 12.1 0.2 0.28 11.0 0.1 1.6 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase Flagellin_D3 PF08884.11 EEB07581.1 - 0.09 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellin D3 domain Ntox44 PF15607.6 EEB07581.1 - 0.14 12.5 0.8 0.23 11.8 0.8 1.4 1 1 0 1 1 1 0 Bacterial toxin 44 Pyrophosphatase PF00719.19 EEB07582.1 - 2.1e-57 193.4 0.1 2.7e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PNK3P PF08645.11 EEB07583.1 - 2.1e-52 177.1 0.0 6.4e-52 175.5 0.0 1.9 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EEB07583.1 - 4.3e-22 78.8 0.1 9e-20 71.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEB07583.1 - 0.00027 20.5 0.7 0.019 14.4 0.7 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EEB07583.1 - 0.01 15.1 0.0 0.039 13.2 0.0 1.9 1 1 2 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 EEB07583.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.11 EEB07583.1 - 0.052 13.6 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain 6PF2K PF01591.18 EEB07583.1 - 0.068 12.5 0.0 2.3 7.5 0.0 2.2 1 1 1 2 2 2 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 EEB07583.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mpp10 PF04006.12 EEB07584.1 - 2.3e-130 435.9 57.5 3.1e-130 435.5 57.5 1.1 1 0 0 1 1 1 1 Mpp10 protein Stealth_CR4 PF17103.5 EEB07584.1 - 0.17 11.8 2.2 17 5.4 0.5 3.0 1 1 1 2 2 2 0 Stealth protein CR4, conserved region 4 RebB PF11747.8 EEB07584.1 - 0.28 11.3 2.2 0.63 10.2 2.2 1.5 1 0 0 1 1 1 0 Killing trait Ribosom_S12_S23 PF00164.25 EEB07585.1 - 1.3e-49 166.6 0.8 1.6e-49 166.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ICE2 PF08426.10 EEB07586.1 - 5.8e-77 259.5 31.0 1.1e-76 258.6 31.0 1.4 1 1 0 1 1 1 1 ICE2 Ras PF00071.22 EEB07587.1 - 2.9e-56 189.5 0.0 3.5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB07587.1 - 5.6e-22 78.2 0.0 1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB07587.1 - 6.5e-07 29.0 0.0 9.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEB07587.1 - 0.00024 20.6 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EEB07587.1 - 0.00076 19.1 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEB07587.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ufd2P_core PF10408.9 EEB07588.1 - 1.2e-198 661.7 11.8 1.6e-198 661.3 11.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EEB07588.1 - 6.6e-29 99.9 0.6 6.6e-29 99.9 0.6 2.5 3 0 0 3 3 3 1 U-box domain HA2 PF04408.23 EEB07589.1 - 8.7e-18 64.6 0.0 1.6e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEB07589.1 - 1.6e-13 51.0 0.5 8.1e-13 48.7 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEB07589.1 - 2.8e-08 34.0 0.0 6.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EEB07589.1 - 5.4e-06 26.7 0.2 1.6e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EEB07589.1 - 0.00025 20.9 0.1 0.00051 19.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EEB07589.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB07589.1 - 0.0041 17.5 0.0 0.014 15.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EEB07589.1 - 0.0089 16.1 0.3 0.19 11.8 0.3 2.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EEB07589.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EEB07589.1 - 0.023 15.2 0.1 0.069 13.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter zf-C2H2_2 PF12756.7 EEB07589.1 - 0.026 14.8 0.2 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_23 PF13476.6 EEB07589.1 - 0.044 14.3 0.2 0.78 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEB07589.1 - 0.046 13.2 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EEB07589.1 - 0.073 13.0 0.1 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EEB07589.1 - 0.25 11.7 1.9 0.73 10.2 0.6 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1604 PF07713.13 EEB07591.1 - 3e-34 116.7 0.6 7.6e-34 115.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch_2 PF12656.7 EEB07591.1 - 0.1 12.7 0.3 1.9 8.7 0.4 2.4 1 1 1 2 2 2 0 G-patch domain Aldolase_II PF00596.21 EEB07592.1 - 1.3e-44 152.3 0.0 1.6e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3095 PF11294.8 EEB07592.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) ResIII PF04851.15 EEB07593.1 - 2.8e-24 86.0 0.0 2.8e-23 82.8 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB07593.1 - 1.2e-19 70.7 0.2 4.9e-19 68.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB07593.1 - 2.1e-12 47.2 0.0 8.7e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEB07593.1 - 0.00048 19.9 0.8 0.0046 16.7 0.0 2.7 3 0 0 3 3 3 1 SWI2/SNF2 ATPase DUF2618 PF10940.8 EEB07593.1 - 0.73 9.7 3.5 2.6 7.9 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) TFIIS_M PF07500.14 EEB07594.1 - 3.3e-32 111.3 1.8 3.3e-32 111.3 1.8 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EEB07594.1 - 2e-18 65.9 9.1 2e-18 65.9 9.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EEB07594.1 - 9.6e-11 41.5 1.2 9.6e-11 41.5 1.2 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain Arm_3 PF16186.5 EEB07594.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Atypical Arm repeat Elf1 PF05129.13 EEB07594.1 - 0.099 12.7 3.0 0.28 11.2 3.0 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SET PF00856.28 EEB07595.1 - 9.2e-14 52.2 0.0 1.8e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Peroxin-13_N PF04088.13 EEB07596.1 - 5.5e-26 91.6 0.0 9.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 EEB07596.1 - 2.6e-12 46.4 0.0 8.2e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEB07596.1 - 5.9e-10 38.7 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEB07596.1 - 2.2e-09 36.8 0.0 6.1e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain Calreticulin PF00262.18 EEB07597.1 - 3.2e-155 516.5 0.5 4.3e-155 516.1 0.5 1.2 1 0 0 1 1 1 1 Calreticulin family CAP_GLY PF01302.25 EEB07598.1 - 9e-17 60.9 1.1 1.4e-16 60.2 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Glu-tRNAGln PF02686.15 EEB07598.1 - 0.0059 16.9 1.8 4.4 7.7 1.0 2.7 2 0 0 2 2 2 2 Glu-tRNAGln amidotransferase C subunit Ferritin_2 PF13668.6 EEB07598.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain DUF1993 PF09351.10 EEB07598.1 - 0.16 12.1 9.8 1.2 9.2 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Goodbye PF17109.5 EEB07598.1 - 1.1 9.7 4.3 10 6.6 0.4 3.0 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain PKcGMP_CC PF16808.5 EEB07598.1 - 1.5 8.7 27.2 0.32 10.9 0.2 6.7 5 2 2 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 EEB07598.1 - 4.1 7.9 25.0 5.4 7.6 2.0 3.8 2 2 1 3 3 3 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EEB07598.1 - 4.1 7.4 10.4 21 5.2 0.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EEB07598.1 - 4.2 6.6 22.2 0.067 12.5 5.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 EEB07598.1 - 7.6 6.6 19.8 7.8 6.5 0.0 6.1 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat G6PD_C PF02781.16 EEB07599.2 - 1.9e-81 273.5 0.0 3.4e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EEB07599.2 - 2.3e-39 135.8 0.0 4.2e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FMN_red PF03358.15 EEB07600.2 - 7.8e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EEB07600.2 - 7.7e-05 22.5 0.6 0.00022 21.0 0.1 1.8 1 1 1 2 2 2 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EEB07600.2 - 0.06 13.5 0.1 2.1 8.5 0.1 2.2 1 1 0 1 1 1 0 Flavodoxin SNF2_N PF00176.23 EEB07601.2 - 3.3e-53 180.6 0.0 6.7e-53 179.6 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EEB07601.2 - 3.2e-08 33.7 0.0 9.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Atg14 PF10186.9 EEB07602.1 - 3e-13 49.5 9.5 4.5e-13 49.0 9.5 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-HC5HC2H PF13771.6 EEB07602.1 - 0.029 14.6 2.0 0.065 13.5 2.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Exonuc_VII_L PF02601.15 EEB07602.1 - 0.19 11.3 3.8 0.28 10.7 3.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit F_actin_cap_B PF01115.17 EEB07603.1 - 4.4e-91 304.8 0.2 5.1e-91 304.5 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Bromodomain PF00439.25 EEB07604.1 - 2.3e-47 159.0 3.1 4.8e-24 84.2 0.1 2.9 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 EEB07604.1 - 1.3e-14 54.1 0.0 3.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF1690 PF07956.11 EEB07604.1 - 0.021 15.3 0.7 15 6.0 0.0 3.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) SesA PF17107.5 EEB07604.1 - 0.12 12.6 0.1 0.44 10.8 0.1 2.0 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FlxA PF14282.6 EEB07604.1 - 0.22 11.5 2.1 2.5 8.1 0.2 3.5 3 0 0 3 3 3 0 FlxA-like protein DIRP PF06584.13 EEB07604.1 - 0.28 11.4 3.4 2.3 8.5 1.5 3.1 3 0 0 3 3 3 0 DIRP Utp12 PF04003.12 EEB07605.1 - 2.8e-19 69.4 0.1 5.9e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF2407_C PF13373.6 EEB07606.1 - 7.3e-20 71.6 7.1 4.7e-19 68.9 7.1 2.0 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EEB07606.1 - 6.4e-19 68.4 0.1 4e-18 65.9 0.1 2.1 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ABC_tran PF00005.27 EEB07607.1 - 2.9e-55 186.5 1.5 6.8e-33 114.1 0.0 4.0 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EEB07607.1 - 2.4e-17 63.7 0.2 6.3e-07 29.5 0.1 3.6 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEB07607.1 - 7.3e-14 51.7 0.0 0.00063 19.2 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EEB07607.1 - 3e-11 43.1 0.2 7e-11 41.9 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EEB07607.1 - 2.2e-09 38.1 3.9 0.0034 17.9 4.1 3.3 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EEB07607.1 - 1.1e-07 31.9 0.0 0.0079 16.3 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EEB07607.1 - 8e-07 28.7 0.4 0.011 15.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEB07607.1 - 1e-06 28.8 0.2 0.0091 15.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EEB07607.1 - 2.8e-05 24.6 1.4 0.33 11.3 0.0 3.3 4 0 0 4 4 2 2 AAA ATPase domain NACHT PF05729.12 EEB07607.1 - 3.9e-05 23.6 0.0 0.078 12.9 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EEB07607.1 - 6.5e-05 23.2 0.0 0.7 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEB07607.1 - 7.7e-05 23.0 0.5 0.13 12.5 0.0 3.8 3 1 1 4 4 2 1 AAA domain RNA_helicase PF00910.22 EEB07607.1 - 8e-05 23.0 0.1 0.83 10.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_15 PF13175.6 EEB07607.1 - 0.00036 20.4 0.2 0.65 9.6 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 EEB07607.1 - 0.00041 20.5 3.5 0.011 15.8 0.5 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain MeaB PF03308.16 EEB07607.1 - 0.00066 18.7 0.2 0.89 8.5 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EEB07607.1 - 0.00075 19.3 0.1 2.1 8.0 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase CLASP_N PF12348.8 EEB07607.1 - 0.0014 18.2 1.9 0.12 11.9 0.2 3.1 3 0 0 3 3 3 1 CLASP N terminal 4HB PF17947.1 EEB07607.1 - 0.0015 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 Four helical bundle domain AAA_33 PF13671.6 EEB07607.1 - 0.0019 18.4 0.0 3.6 7.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain HEAT PF02985.22 EEB07607.1 - 0.0021 18.1 5.2 3.9 8.0 0.1 4.9 5 0 0 5 5 4 1 HEAT repeat AAA PF00004.29 EEB07607.1 - 0.0022 18.4 0.0 4.3 7.8 0.0 3.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EEB07607.1 - 0.0026 17.8 0.0 3.4 7.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.25 EEB07607.1 - 0.003 17.2 0.1 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EEB07607.1 - 0.0032 16.7 0.3 0.21 10.8 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain HEAT_2 PF13646.6 EEB07607.1 - 0.004 17.5 8.8 0.057 13.8 0.1 4.4 2 1 1 4 4 4 1 HEAT repeats Dynamin_N PF00350.23 EEB07607.1 - 0.0043 17.1 0.4 0.48 10.5 0.0 3.4 3 0 0 3 3 2 1 Dynamin family Adaptin_N PF01602.20 EEB07607.1 - 0.0049 15.5 3.7 0.017 13.7 0.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region AAA_18 PF13238.6 EEB07607.1 - 0.0063 17.1 0.0 0.76 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMS19_C PF12460.8 EEB07607.1 - 0.0081 15.3 1.7 0.062 12.4 0.1 2.7 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal AAA_30 PF13604.6 EEB07607.1 - 0.011 15.4 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EEB07607.1 - 0.012 15.5 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 EEB07607.1 - 0.014 15.6 0.0 4.8 7.4 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 EEB07607.1 - 0.017 14.7 0.0 7.6 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EEB07607.1 - 0.019 14.9 0.3 10 6.0 0.2 3.7 4 0 0 4 4 4 0 NTPase AAA_24 PF13479.6 EEB07607.1 - 0.019 14.7 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EEB07607.1 - 0.026 13.7 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEB07607.1 - 0.042 13.4 0.1 14 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 EEB07607.1 - 0.055 12.9 0.1 9 5.7 0.0 3.5 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 EEB07607.1 - 0.058 13.0 0.1 15 5.1 0.1 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EEB07607.1 - 0.061 13.2 0.0 8.4 6.3 0.0 3.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.15 EEB07607.1 - 0.066 12.0 0.0 9.6 4.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 EEB07607.1 - 0.11 12.0 0.0 7.7 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EEB07607.1 - 0.16 11.3 2.0 11 5.3 0.1 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 EEB07607.1 - 0.3 11.0 6.4 5.7 6.8 0.0 3.2 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea ATE_C PF04377.15 EEB07608.2 - 2.5e-48 164.1 7.3 2.7e-48 164.0 5.6 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EEB07608.2 - 3.7e-26 91.3 1.8 2.2e-25 88.8 1.6 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 EEB07608.2 - 0.081 13.1 0.3 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Syja_N PF02383.18 EEB07609.2 - 1.1e-72 245.0 0.1 1.5e-72 244.7 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Pil1 PF13805.6 EEB07610.1 - 9.2e-98 326.9 0.6 2.6e-94 315.6 0.6 2.3 1 1 0 1 1 1 1 Eisosome component PIL1 Rad51 PF08423.11 EEB07611.1 - 2.6e-10 40.0 0.1 0.00014 21.2 0.1 2.4 1 1 1 2 2 2 2 Rad51 RecA PF00154.21 EEB07611.1 - 2.6e-08 33.6 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EEB07611.1 - 4.3e-08 33.0 0.0 1.7e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EEB07611.1 - 8.5e-06 25.3 0.3 3e-05 23.5 0.1 2.0 2 1 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 EEB07611.1 - 1.6e-05 24.7 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 EEB07611.1 - 3.3e-05 23.9 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DnaB_C PF03796.15 EEB07611.1 - 3.6e-05 23.2 0.4 0.00027 20.3 0.1 2.4 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EEB07611.1 - 0.00016 21.9 0.1 0.00038 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EEB07611.1 - 0.00086 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEB07611.1 - 0.0011 19.5 0.2 0.0025 18.3 0.2 1.8 1 1 0 1 1 1 1 ABC transporter CbiA PF01656.23 EEB07611.1 - 0.0015 18.6 0.3 0.0024 17.9 0.3 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EEB07611.1 - 0.005 17.0 0.2 0.019 15.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EEB07611.1 - 0.0053 16.2 0.1 0.0094 15.4 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 EEB07611.1 - 0.014 15.8 0.5 0.081 13.3 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EEB07611.1 - 0.017 15.7 0.1 0.036 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EEB07611.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.15 EEB07611.1 - 0.029 14.7 0.2 0.12 12.6 0.2 2.0 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_28 PF13521.6 EEB07611.1 - 0.03 14.6 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEB07611.1 - 0.031 14.7 0.1 0.071 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EEB07611.1 - 0.052 12.7 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 EEB07611.1 - 0.063 13.1 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 EEB07611.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 NTPase Helicase_RecD PF05127.14 EEB07611.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.6 EEB07611.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB07611.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 EEB07611.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 EEB07611.1 - 0.18 11.5 0.3 0.38 10.5 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EEB07611.1 - 0.79 10.2 2.5 0.59 10.6 0.2 1.9 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EEB07611.1 - 0.84 9.3 3.6 0.61 9.8 0.2 2.3 2 2 1 3 3 3 0 Cytidylate kinase Fungal_trans PF04082.18 EEB07612.1 - 5.5e-25 87.9 0.1 1.2e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB07612.1 - 8.6e-09 35.4 8.5 1.8e-08 34.4 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 EEB07614.1 - 5.8e-39 134.6 1.4 7.3e-39 134.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 EEB07614.1 - 0.0017 17.7 0.9 0.95 8.6 0.1 3.3 3 1 0 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Phage_TAC_2 PF06894.11 EEB07614.1 - 0.2 11.5 0.0 0.53 10.1 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Pkinase PF00069.25 EEB07615.1 - 8.7e-60 202.3 0.0 1.2e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07615.1 - 2.4e-29 102.4 0.0 7.6e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PAS_12 PF18095.1 EEB07615.1 - 0.077 12.6 0.1 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 UPF0242 C-terminal PAS-like domain 6PF2K PF01591.18 EEB07616.1 - 8.5e-42 143.0 0.4 3.4e-40 137.7 0.4 2.1 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEB07616.1 - 1.3e-32 113.1 0.0 2.7e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 EEB07616.1 - 0.0099 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 BRICHOS PF04089.14 EEB07616.1 - 0.019 15.2 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 BRICHOS domain EcoRII-N PF09217.10 EEB07616.1 - 0.063 13.0 0.2 0.77 9.5 0.0 2.6 3 0 0 3 3 3 0 Restriction endonuclease EcoRII, N-terminal DUF726 PF05277.12 EEB07618.1 - 5.5e-120 400.4 0.3 7.7e-120 399.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 EEB07618.1 - 0.0017 19.0 2.4 0.075 13.6 0.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.11 EEB07618.1 - 0.03 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 EEB07618.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold NblA PF04485.12 EEB07618.1 - 0.63 10.5 4.3 1.2 9.5 0.1 2.8 2 1 1 3 3 3 0 Phycobilisome degradation protein nblA DUF3040 PF11239.8 EEB07618.1 - 1.4 9.2 10.1 2.6 8.4 4.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) CLN3 PF02487.17 EEB07619.1 - 1.3e-116 390.0 27.4 1.6e-115 386.3 27.4 1.9 1 1 0 1 1 1 1 CLN3 protein Steroid_dh PF02544.16 EEB07620.2 - 1.3e-42 145.3 7.9 1.3e-42 145.3 7.9 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 EEB07620.2 - 3.1e-07 30.0 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 EEB07620.2 - 0.0027 17.3 2.1 0.0027 17.3 2.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EEB07620.2 - 0.0047 17.3 0.3 0.0047 17.3 0.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase YukD PF08817.10 EEB07620.2 - 0.13 13.0 0.1 0.21 12.3 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Glyco_hydro_71 PF03659.14 EEB07621.2 - 6.4e-103 344.4 6.3 8.2e-103 344.1 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SQS_PSY PF00494.19 EEB07622.1 - 6.4e-36 124.2 0.0 8.7e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4519 PF15012.6 EEB07622.1 - 0.073 13.2 0.8 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Cyd_oper_YbgE PF09600.10 EEB07622.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) PAP_central PF04928.17 EEB07623.1 - 2.1e-111 370.9 0.0 2.7e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EEB07623.1 - 1.8e-61 206.7 0.4 3.3e-61 205.9 0.4 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EEB07623.1 - 2.3e-12 47.1 0.0 7e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEB07623.1 - 0.043 13.9 0.0 0.19 11.8 0.0 2.0 1 1 1 2 2 2 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EEB07623.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Amidase PF01425.21 EEB07624.1 - 5e-114 381.7 0.0 6.1e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Aquarius_N PF16399.5 EEB07625.2 - 9.4e-68 229.0 13.8 1.3e-67 228.5 13.8 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EEB07625.2 - 9.6e-13 48.2 0.0 3e-10 40.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EEB07625.2 - 0.0032 16.6 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 EEB07625.2 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EEB07625.2 - 0.0085 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEB07625.2 - 0.013 15.8 0.1 0.074 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EEB07625.2 - 0.024 14.6 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EEB07625.2 - 0.027 15.0 0.4 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EEB07625.2 - 0.028 14.8 0.0 0.51 10.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEB07625.2 - 0.037 14.6 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 EEB07625.2 - 0.066 12.6 0.4 0.42 10.0 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DnaB_C PF03796.15 EEB07625.2 - 0.091 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CbiA PF01656.23 EEB07625.2 - 0.19 11.8 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAT PF02259.23 EEB07626.1 - 1.6e-127 425.5 8.8 4.1e-127 424.2 8.8 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EEB07626.1 - 2.1e-74 250.5 0.1 4.1e-74 249.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EEB07626.1 - 4e-63 212.1 13.4 2.3e-61 206.4 0.3 4.8 5 1 0 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EEB07626.1 - 1.7e-45 153.4 0.4 1.6e-44 150.3 0.0 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EEB07626.1 - 3.7e-15 55.4 0.7 1e-14 54.0 0.7 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EEB07626.1 - 4.5e-14 52.6 12.2 0.00092 19.6 0.0 10.0 10 1 2 12 12 12 3 HEAT repeats HEAT PF02985.22 EEB07626.1 - 1e-12 47.1 12.0 0.022 15.0 0.0 10.6 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 EEB07626.1 - 2.3e-11 44.0 18.6 7.6e-06 26.3 0.0 10.8 13 0 0 13 13 10 2 HEAT-like repeat IFRD PF05004.13 EEB07626.1 - 2.6e-05 23.5 3.8 0.24 10.4 0.0 4.4 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) ANAPC3 PF12895.7 EEB07626.1 - 0.0003 21.0 3.7 2.6 8.4 0.1 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 BAF250_C PF12031.8 EEB07626.1 - 0.00087 18.7 0.7 0.03 13.6 0.0 2.9 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa UME PF08064.13 EEB07626.1 - 0.007 16.3 4.7 1.4 8.9 0.0 5.6 3 1 1 4 4 4 1 UME (NUC010) domain Cnd1 PF12717.7 EEB07626.1 - 0.051 13.6 10.4 17 5.4 0.1 6.1 4 2 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EEB07626.1 - 0.073 12.8 1.6 23 4.7 0.0 4.9 4 1 0 5 5 5 0 rRNA processing/ribosome biogenesis DUF294_C PF10335.9 EEB07626.1 - 0.15 11.8 0.3 0.52 10.1 0.1 2.0 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain TPR_7 PF13176.6 EEB07626.1 - 0.34 11.0 2.0 14 6.0 0.2 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB07626.1 - 4.9 7.5 7.9 23 5.4 0.8 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TIMELESS PF04821.14 EEB07627.1 - 3.7e-65 220.0 1.4 3.7e-65 220.0 1.4 2.8 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 EEB07627.1 - 1.4e-14 54.2 0.0 1.4e-14 54.2 0.0 3.8 5 0 0 5 5 5 1 Timeless protein C terminal region PAP_assoc PF03828.19 EEB07628.1 - 2.4e-13 50.1 0.0 5.8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEB07628.1 - 0.00031 21.0 0.0 0.00094 19.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1830 PF08865.11 EEB07628.1 - 0.011 15.8 0.1 0.031 14.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) DNA_pol_B_palm PF14792.6 EEB07628.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase beta palm EAV_GS PF01309.18 EEB07628.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Acetyltransf_1 PF00583.25 EEB07629.1 - 5.3e-14 52.5 0.0 6.1e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB07629.1 - 7.4e-12 45.3 0.0 9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB07629.1 - 1.8e-08 34.6 0.0 2.8e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EEB07629.1 - 9.2e-06 25.4 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EEB07629.1 - 0.0039 17.3 0.0 0.0072 16.4 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EEB07629.1 - 0.0059 16.5 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EEB07629.1 - 0.043 13.3 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 EEB07629.1 - 0.15 12.7 0.0 0.17 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRP PF06011.12 EEB07630.1 - 2.4e-49 168.2 30.7 4.2e-49 167.4 30.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEB07630.1 - 2.8e-35 121.7 0.1 4.7e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Kinocilin PF15033.6 EEB07630.1 - 0.068 12.8 0.2 15 5.2 0.0 3.0 3 0 0 3 3 3 0 Kinocilin protein WBP-1 PF11669.8 EEB07630.1 - 1.1 9.9 4.7 0.37 11.5 0.3 2.5 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF3818 PF12825.7 EEB07631.1 - 5.7e-88 295.2 0.0 7.7e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EEB07631.1 - 5.9e-25 87.8 0.0 1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 PX-associated PP-binding PF00550.25 EEB07631.1 - 0.12 12.8 0.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Phosphopantetheine attachment site ApbA PF02558.16 EEB07632.1 - 1.3e-21 76.9 0.0 3.3e-21 75.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EEB07632.1 - 1.2e-19 70.7 0.0 2.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GATA PF00320.27 EEB07633.1 - 1.8e-15 56.2 2.6 3.3e-15 55.4 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EEB07633.1 - 1.6e-11 43.8 0.5 3.7e-11 42.6 0.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FAM163 PF15069.6 EEB07633.1 - 0.87 10.0 9.1 0.7 10.3 4.2 2.6 2 0 0 2 2 2 0 FAM163 family DASH_Hsk3 PF08227.11 EEB07634.1 - 9.5e-17 61.1 3.1 1.2e-16 60.8 3.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like GvpK PF05121.12 EEB07634.1 - 0.0066 16.5 0.5 0.012 15.6 0.5 1.5 1 1 0 1 1 1 1 Gas vesicle protein K LPP PF04728.13 EEB07634.1 - 0.067 13.6 0.6 0.12 12.8 0.6 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Sel1 PF08238.12 EEB07635.1 - 1e-29 102.3 11.3 3.8e-05 24.2 0.5 6.3 6 0 0 6 6 6 6 Sel1 repeat TPP_enzyme_N PF02776.18 EEB07636.1 - 9.1e-30 103.5 0.0 1.4e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEB07636.1 - 5.8e-20 71.4 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEB07636.1 - 2.3e-17 63.2 0.0 9e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EEB07636.1 - 0.00055 19.2 0.0 0.00087 18.6 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MFS_1 PF07690.16 EEB07637.1 - 4.4e-19 68.6 48.1 2e-17 63.2 47.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB07637.1 - 4.8e-12 45.1 14.7 4.8e-12 45.1 14.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ac76 PF05814.11 EEB07637.1 - 2.8 8.0 5.0 4 7.5 1.2 3.1 2 0 0 2 2 2 0 Orf76 (Ac76) Pkinase PF00069.25 EEB07638.1 - 3.4e-58 197.1 0.0 5e-57 193.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07638.1 - 6.6e-27 94.4 0.0 1.1e-19 70.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EEB07638.1 - 0.025 15.3 0.3 0.065 13.9 0.3 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 EEB07638.1 - 0.053 12.4 0.1 0.11 11.4 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EEB07638.1 - 0.055 12.8 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EEB07638.1 - 0.058 12.7 1.1 0.089 12.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB07638.1 - 0.11 12.4 0.0 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mto2_bdg PF12808.7 EEB07639.1 - 5.1e-22 77.9 7.1 5.1e-22 77.9 7.1 8.9 9 2 1 10 10 10 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 EEB07639.1 - 2.8e-19 69.0 5.3 2.8e-19 69.0 5.3 11.9 5 1 6 11 11 11 1 Centrosomin N-terminal motif 1 DUF4156 PF13698.6 EEB07639.1 - 2 8.8 6.4 18 5.7 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4156) ABC_tran PF00005.27 EEB07640.1 - 2.2e-45 154.5 0.0 2e-22 80.2 0.0 4.0 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EEB07640.1 - 7.7e-17 61.1 0.4 2.4e-16 59.5 0.4 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EEB07640.1 - 8.9e-15 55.3 1.5 0.0059 16.5 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEB07640.1 - 2.6e-11 43.4 0.1 0.0059 16.1 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEB07640.1 - 8.3e-09 35.8 0.1 0.02 15.2 0.0 5.0 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EEB07640.1 - 3e-08 33.3 0.0 0.0074 16.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EEB07640.1 - 4.9e-08 33.7 8.6 0.0062 17.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EEB07640.1 - 1e-07 32.0 0.0 0.0017 18.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEB07640.1 - 2.6e-07 30.7 0.0 0.016 15.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EEB07640.1 - 1.3e-06 28.4 0.0 0.1 12.3 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 EEB07640.1 - 6.7e-06 26.4 0.0 0.21 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMS19_N PF14500.6 EEB07640.1 - 1.4e-05 24.8 0.5 0.34 10.4 0.0 4.2 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II AAA_33 PF13671.6 EEB07640.1 - 1.6e-05 25.1 0.0 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EEB07640.1 - 1.8e-05 24.8 0.2 0.0061 16.6 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_18 PF13238.6 EEB07640.1 - 1.9e-05 25.2 0.0 0.35 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EEB07640.1 - 4.5e-05 23.9 0.0 0.43 11.0 0.0 3.9 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EEB07640.1 - 6e-05 23.4 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 EEB07640.1 - 6.8e-05 23.3 0.0 0.26 11.7 0.0 3.4 2 0 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EEB07640.1 - 0.00015 20.8 0.2 0.37 9.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EEB07640.1 - 0.00017 21.8 1.3 0.06 13.4 0.1 3.3 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_24 PF13479.6 EEB07640.1 - 0.00022 21.0 0.2 1 9.1 0.1 3.5 3 0 0 3 3 3 1 AAA domain CLP1_P PF16575.5 EEB07640.1 - 0.00027 20.8 0.0 0.065 13.0 0.0 3.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_27 PF13514.6 EEB07640.1 - 0.00043 19.9 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEB07640.1 - 0.0012 18.6 0.1 2.8 7.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 EEB07640.1 - 0.0015 18.5 0.0 0.81 9.6 0.0 3.3 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EEB07640.1 - 0.0016 18.5 0.0 4.1 7.4 0.0 3.6 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 EEB07640.1 - 0.0019 18.2 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EEB07640.1 - 0.0027 17.7 0.0 2.4 8.1 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.13 EEB07640.1 - 0.003 16.7 0.1 1.3 8.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) cobW PF02492.19 EEB07640.1 - 0.0044 16.6 0.0 1.2 8.7 0.0 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EEB07640.1 - 0.0068 16.6 0.0 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 EEB07640.1 - 0.01 15.6 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 EEB07640.1 - 0.011 15.0 0.0 0.53 9.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 EEB07640.1 - 0.018 14.3 0.1 9.8 5.4 0.0 3.1 3 0 0 3 3 3 0 Septin NTPase_1 PF03266.15 EEB07640.1 - 0.021 14.7 0.3 11 5.9 0.0 3.1 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 EEB07640.1 - 0.023 14.5 0.0 2 8.2 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EEB07640.1 - 0.023 14.2 0.0 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MutS_V PF00488.21 EEB07640.1 - 0.023 14.7 0.0 9.2 6.2 0.0 2.7 2 0 0 2 2 2 0 MutS domain V Mg_chelatase PF01078.21 EEB07640.1 - 0.037 13.4 0.1 0.73 9.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MukB PF04310.12 EEB07640.1 - 0.038 13.8 0.1 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal ATP_bind_1 PF03029.17 EEB07640.1 - 0.042 13.6 0.1 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 EEB07640.1 - 0.046 13.7 1.5 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EEB07640.1 - 0.049 13.4 0.0 8.4 6.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PIN7 PF18475.1 EEB07640.1 - 0.056 14.1 0.0 4.7 7.9 0.0 2.6 2 0 0 2 2 2 0 PIN domain AAA_13 PF13166.6 EEB07640.1 - 0.076 11.6 0.1 10 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EEB07640.1 - 0.087 12.4 0.0 12 5.4 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HEAT PF02985.22 EEB07640.1 - 0.18 12.2 0.1 1.7e+02 2.9 0.0 4.5 5 0 0 5 5 3 0 HEAT repeat DUF3437 PF11919.8 EEB07640.1 - 0.55 10.2 3.1 4.5 7.3 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3437) AMP-binding PF00501.28 EEB07642.1 - 6.2e-89 298.5 0.1 7.5e-89 298.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEB07642.1 - 1.9e-24 86.4 0.8 4.6e-24 85.2 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEB07642.1 - 2.3e-18 65.8 1.7 5.2e-18 64.7 0.3 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Cytochrom_C PF00034.21 EEB07643.1 - 3.1e-12 47.5 0.1 4.5e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EEB07643.1 - 5.5e-08 33.0 2.5 2.9e-07 30.7 2.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EEB07643.1 - 0.022 14.4 0.2 0.061 13.0 0.1 1.7 2 0 0 2 2 2 0 Cytochrome c-550 domain CCP_MauG PF03150.14 EEB07643.1 - 0.11 13.2 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Yae1_N PF09811.9 EEB07644.1 - 1.3e-09 37.5 3.3 2.1e-09 36.9 3.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal zf-C3HC4_3 PF13920.6 EEB07645.1 - 1.8e-08 34.1 10.1 1.8e-08 34.1 10.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 EEB07646.2 - 6.4e-31 106.1 1.5 2.6e-30 104.1 0.4 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EEB07646.2 - 9e-11 41.5 1.0 2.5e-10 40.1 0.9 1.8 2 0 0 2 2 2 1 DEK C terminal domain Ribosomal_60s PF00428.19 EEB07646.2 - 0.3 11.7 21.6 0.66 10.6 7.7 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein CDC45 PF02724.14 EEB07646.2 - 0.64 8.2 6.2 0.74 8.0 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MutS_V PF00488.21 EEB07647.1 - 6.7e-75 251.3 0.3 1.1e-74 250.5 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEB07647.1 - 3.5e-37 128.5 0.0 1e-36 127.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EEB07647.1 - 1.1e-33 115.8 0.3 1.1e-33 115.8 0.3 2.2 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 EEB07647.1 - 1e-16 61.5 0.0 2.9e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EEB07647.1 - 1.3e-14 54.3 0.8 3.1e-14 53.1 0.8 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 EEB07647.1 - 0.0019 18.7 0.3 0.12 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEB07647.1 - 0.012 15.7 0.2 0.11 12.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EEB07647.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEB07647.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S28e PF01200.18 EEB07648.1 - 4.7e-33 113.0 1.6 5.2e-33 112.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TRAPPC10 PF12584.8 EEB07649.2 - 1.2e-09 38.0 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.28 EEB07649.2 - 0.12 12.3 0.3 19 5.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CAMSAP_CH PF11971.8 EEB07649.2 - 0.68 9.8 3.7 1.8 8.5 0.4 3.1 3 0 0 3 3 3 0 CAMSAP CH domain MFS_1 PF07690.16 EEB07650.1 - 1.7e-39 135.8 14.7 6.7e-33 114.1 9.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EEB07650.1 - 0.02 13.2 14.6 0.0035 15.7 5.1 3.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 EEB07650.1 - 0.028 13.4 0.0 0.028 13.4 0.0 1.9 3 0 0 3 3 3 0 PUCC protein Sugar_tr PF00083.24 EEB07650.1 - 0.14 11.0 17.7 0.15 10.9 1.4 2.9 2 1 2 4 4 4 0 Sugar (and other) transporter R3H PF01424.22 EEB07651.1 - 1.6e-15 56.8 0.1 3.8e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EEB07651.1 - 2.9e-07 30.4 105.6 5.3e-05 23.2 13.9 14.1 14 2 1 15 15 15 7 NF-X1 type zinc finger Sec10 PF07393.11 EEB07652.1 - 2.1e-83 281.0 11.1 5.1e-83 279.8 8.4 2.4 1 1 1 2 2 2 1 Exocyst complex component Sec10 F-box-like PF12937.7 EEB07652.1 - 2.1e-05 24.3 0.2 5.5e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEB07652.1 - 0.00071 19.4 0.1 0.0022 17.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EEB07653.1 - 3.2e-63 208.2 21.8 5.7e-10 39.6 0.2 9.4 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07653.1 - 6.1e-18 64.9 3.0 0.029 14.7 0.0 6.4 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EEB07653.1 - 7.9e-10 39.1 0.1 1.7e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 EEB07653.1 - 6.6e-09 35.9 0.0 0.00013 21.9 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEB07653.1 - 8.9e-09 34.5 4.6 0.049 12.3 0.1 4.5 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEB07653.1 - 8.9e-07 28.2 1.1 0.043 12.8 0.0 4.3 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEB07653.1 - 0.00012 21.6 0.0 0.45 9.8 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Cytochrom_D1 PF02239.16 EEB07653.1 - 0.0061 15.1 0.0 0.015 13.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 EEB07653.1 - 0.037 14.0 3.1 0.94 9.5 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2048 PF09752.9 EEB07653.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Nbas_N PF15492.6 EEB07653.1 - 0.074 12.4 3.6 0.91 8.8 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FAD_binding_9 PF08021.11 EEB07653.1 - 0.11 12.7 0.0 0.89 9.8 0.0 2.4 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain Ribosomal_L31e PF01198.19 EEB07654.2 - 1.2e-40 137.6 1.8 2e-40 136.9 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EEB07654.2 - 0.037 14.1 0.1 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF1104 PF06518.11 EEB07654.2 - 0.18 12.2 2.0 0.21 12.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Methyltransf_25 PF13649.6 EEB07655.2 - 1.8e-13 51.0 0.2 1.4e-12 48.1 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB07655.2 - 4.2e-12 46.1 0.0 7.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB07655.2 - 2.9e-11 43.3 0.0 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EEB07655.2 - 4e-11 43.4 0.1 3.2e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB07655.2 - 1.6e-08 34.6 0.0 1.6e-07 31.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEB07655.2 - 1.2e-07 31.0 0.1 1.8e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EEB07655.2 - 8.2e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EEB07655.2 - 1.6e-05 25.6 0.1 5.5e-05 23.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EEB07655.2 - 2.4e-05 24.0 0.1 4.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EEB07655.2 - 4.2e-05 22.9 0.1 8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 EEB07655.2 - 0.00016 21.6 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EEB07655.2 - 0.0046 17.0 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EEB07655.2 - 0.0048 17.0 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 EEB07655.2 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 EEB07655.2 - 0.0094 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PRMT5 PF05185.16 EEB07655.2 - 0.017 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 EEB07655.2 - 0.019 16.0 0.0 0.048 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EEB07655.2 - 0.023 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EEB07655.2 - 0.027 13.8 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5_C PF17286.2 EEB07655.2 - 0.049 13.5 0.1 0.076 12.9 0.1 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain NitrOD2 PF18550.1 EEB07655.2 - 0.049 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Nitrososphaera output domain 2 TehB PF03848.14 EEB07655.2 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Nucleoporin_N PF08801.11 EEB07656.1 - 1.2e-90 304.4 2.0 1.2e-90 304.4 0.6 1.7 2 0 0 2 2 2 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EEB07656.1 - 2e-53 182.1 4.5 3.8e-53 181.2 4.2 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2016 PF09436.10 EEB07656.1 - 0.091 12.6 0.0 20 5.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) DUF2279 PF10043.9 EEB07656.1 - 0.13 13.0 0.1 0.73 10.6 0.0 2.3 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) G-patch PF01585.23 EEB07657.2 - 7.6e-12 44.9 0.4 1.7e-11 43.9 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEB07657.2 - 0.0017 18.4 0.1 0.0017 18.4 0.1 3.4 3 2 0 3 3 3 1 G-patch domain Macoilin PF09726.9 EEB07657.2 - 0.032 12.8 32.6 0.04 12.5 32.6 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 EEB07657.2 - 0.26 10.3 24.9 0.32 10.1 24.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SRP-alpha_N PF04086.13 EEB07657.2 - 0.64 9.9 35.7 0.88 9.4 35.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 EEB07657.2 - 0.7 8.7 19.8 0.91 8.3 19.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIF_alpha PF05793.12 EEB07657.2 - 0.85 8.1 39.6 1.2 7.7 39.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp-B-Hydro_N PF05279.11 EEB07657.2 - 2.7 8.0 23.5 3.7 7.6 23.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF936 PF06075.12 EEB07657.2 - 2.7 6.8 37.1 3.4 6.5 37.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF572 PF04502.13 EEB07657.2 - 3.4 7.2 30.7 5.5 6.5 30.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CRT10 PF08728.10 EEB07657.2 - 4.6 5.3 15.6 5.5 5.0 15.6 1.1 1 0 0 1 1 1 0 CRT10 NLE PF08154.12 EEB07658.1 - 4.6e-24 84.7 0.1 8.7e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EEB07658.1 - 8e-15 55.0 18.4 3.2e-05 24.6 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 EEB07658.1 - 2.8e-05 23.0 8.4 0.01 14.5 0.3 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Pkinase PF00069.25 EEB07659.1 - 3e-68 230.1 0.0 4.1e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07659.1 - 5.7e-44 150.3 0.0 8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07659.1 - 1.8e-07 30.8 0.0 5e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEB07659.1 - 0.00049 19.2 0.3 0.00049 19.2 0.3 2.9 2 2 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EEB07659.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_TACC PF12709.7 EEB07660.1 - 5e-09 36.5 33.9 7.7e-09 35.9 3.2 5.0 2 2 2 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 EEB07660.1 - 0.0025 17.2 14.5 0.0025 17.2 14.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) ZapB PF06005.12 EEB07660.1 - 0.015 15.7 1.2 0.015 15.7 1.2 4.0 2 1 1 3 3 2 0 Cell division protein ZapB Filament PF00038.21 EEB07660.1 - 0.024 14.2 27.5 0.32 10.5 0.5 2.5 2 1 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 EEB07660.1 - 0.065 13.3 33.4 0.043 13.9 15.3 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 EEB07660.1 - 0.28 11.4 30.0 0.44 10.8 0.4 3.5 2 2 1 3 3 3 0 Tho complex subunit 7 Lant_dehydr_C PF14028.6 EEB07660.1 - 0.44 10.0 6.2 0.35 10.4 3.9 2.0 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term CCDC144C PF14915.6 EEB07660.1 - 0.49 9.4 32.1 0.051 12.7 15.8 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 EEB07660.1 - 0.63 9.5 30.9 0.26 10.7 9.5 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 APG6_N PF17675.1 EEB07660.1 - 1.1 9.8 35.9 0.17 12.4 3.1 3.7 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF4286 PF14114.6 EEB07660.1 - 1.5 9.4 7.2 0.5 10.9 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) DUF1079 PF06435.11 EEB07660.1 - 5 7.5 10.7 0.79 10.0 1.8 3.6 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) ALMT PF11744.8 EEB07660.1 - 8.2 5.1 12.5 13 4.4 12.5 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Mitoc_mL59 PF18126.1 EEB07661.2 - 2.2e-25 89.5 7.7 3.6e-25 88.7 7.7 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 RhoGEF67_u2 PF16614.5 EEB07661.2 - 1.1 9.4 4.5 0.52 10.4 0.3 2.2 1 1 1 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 LNS2 PF08235.13 EEB07662.1 - 8.2e-96 319.8 0.0 1.1e-95 319.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EEB07662.1 - 8.1e-44 147.8 0.0 1.6e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EEB07662.1 - 0.00019 21.1 0.0 0.0021 17.7 0.0 2.5 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 EEB07662.1 - 0.0024 18.7 5.6 0.007 17.2 5.6 1.8 1 0 0 1 1 1 1 Putative WW-binding domain and destruction box tRNA_synt_1c_R2 PF04557.15 EEB07662.1 - 4.5 8.3 8.4 13 6.7 8.4 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PCI PF01399.27 EEB07663.1 - 0.0029 18.1 0.0 0.0042 17.6 0.0 1.4 1 1 0 1 1 1 1 PCI domain Sigma70_r1_1 PF03979.14 EEB07663.1 - 0.012 15.6 0.3 0.27 11.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 BRCA2 PF00634.18 EEB07663.1 - 0.17 11.6 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 BRCA2 repeat NPR2 PF06218.11 EEB07664.1 - 1.9e-117 392.7 7.6 3.8e-56 190.7 4.9 3.0 1 1 2 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.13 EEB07664.1 - 0.00029 19.8 0.5 0.064 12.0 0.2 2.8 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Amidohydro_1 PF01979.20 EEB07665.1 - 3.7e-71 240.2 0.5 5.8e-71 239.6 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EEB07665.1 - 6e-52 175.1 1.6 1.2e-51 174.1 1.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EEB07665.1 - 2.5e-39 133.2 0.0 5e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EEB07665.1 - 2.9e-36 123.7 0.0 6.2e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EEB07665.1 - 1.7e-07 31.1 0.0 0.00013 21.6 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Urease_linker PF18473.1 EEB07665.1 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Urease subunit beta-alpha linker domain Amidohydro_2 PF04909.14 EEB07665.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase TMEM52 PF14979.6 EEB07666.2 - 0.0069 16.3 0.5 0.021 14.7 0.5 1.8 1 0 0 1 1 1 1 Transmembrane 52 WD40 PF00400.32 EEB07667.1 - 6.8e-13 48.9 5.7 5.7e-05 23.8 0.5 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07667.1 - 6.1e-08 32.9 3.6 0.081 13.2 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB07667.1 - 1.7e-06 28.1 0.2 0.0028 17.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EEB07667.1 - 7.6e-06 24.7 0.1 0.11 11.0 0.0 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain AcetylCoA_hydro PF02550.15 EEB07668.1 - 5.4e-47 160.3 0.0 8.6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EEB07668.1 - 2e-43 148.0 0.0 3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 EEB07668.1 - 0.096 12.1 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Coenzyme A transferase CitF PF04223.12 EEB07668.1 - 0.14 11.0 0.0 0.35 9.7 0.1 1.6 2 0 0 2 2 2 0 Citrate lyase, alpha subunit (CitF) Putative_PNPOx PF01243.20 EEB07669.1 - 2.1e-12 47.1 0.0 5.9e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EEB07669.1 - 0.0024 17.9 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EEB07669.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Rad1 PF02144.16 EEB07670.1 - 4.9e-63 212.8 1.1 5.6e-63 212.6 1.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CTNNBL PF08216.11 EEB07671.1 - 5.7e-34 116.4 0.3 2e-33 114.7 0.3 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 EEB07671.1 - 0.0059 16.6 3.8 0.12 12.5 0.2 3.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Bromodomain PF00439.25 EEB07672.1 - 3.4e-24 84.7 4.6 3.7e-24 84.6 1.9 2.5 2 1 1 3 3 3 1 Bromodomain Acetyltransf_1 PF00583.25 EEB07672.1 - 4.1e-08 33.5 0.1 8.4e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB07672.1 - 1.1e-06 28.6 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB07672.1 - 0.00043 20.6 0.3 0.00085 19.7 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OTU PF02338.19 EEB07673.1 - 8.7e-28 97.4 0.5 3.2e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EEB07673.1 - 5.9e-08 32.5 0.1 5.9e-08 32.5 0.1 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain DUF4407 PF14362.6 EEB07673.1 - 0.99 8.7 11.9 1.4 8.2 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G-patch PF01585.23 EEB07674.1 - 0.066 13.1 0.4 0.26 11.2 0.4 2.0 1 1 0 1 1 1 0 G-patch domain Band_3_cyto PF07565.13 EEB07674.1 - 0.36 10.6 6.9 0.5 10.1 6.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain G-patch_2 PF12656.7 EEB07674.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.7 2 1 0 2 2 2 0 G-patch domain RR_TM4-6 PF06459.12 EEB07674.1 - 0.42 10.4 14.1 0.45 10.3 14.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Thg1C PF14413.6 EEB07674.1 - 1.7 8.8 16.7 14 5.8 16.7 2.0 1 1 0 1 1 1 0 Thg1 C terminal domain V_ATPase_I PF01496.19 EEB07674.1 - 1.9 6.3 10.5 2.3 6.0 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EEB07674.1 - 4.2 6.0 11.0 4.6 5.9 11.0 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EEB07674.1 - 4.8 6.3 11.7 5.1 6.2 11.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EEB07674.1 - 4.9 7.1 6.8 5.5 7.0 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 EEB07674.1 - 5.9 5.6 14.1 6.6 5.5 14.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PIG-U PF06728.13 EEB07675.1 - 9.7e-91 304.6 35.8 1.2e-90 304.3 35.8 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ribosomal_S11 PF00411.19 EEB07676.1 - 1.8e-10 41.2 0.0 2.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Clr2_transil PF16761.5 EEB07677.2 - 2e-21 76.6 0.1 4.8e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EEB07677.2 - 8.1e-10 39.7 0.0 2.2e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 MFS_1 PF07690.16 EEB07678.1 - 1.6e-28 99.6 35.4 2.3e-28 99.2 35.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07678.1 - 0.001 18.0 4.7 0.001 18.0 4.7 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB07679.1 - 3.9e-28 98.4 27.1 3.9e-28 98.4 27.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_C PF00137.21 EEB07680.2 - 4.5e-14 52.5 25.1 9.1e-12 45.1 11.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PMM PF03332.13 EEB07681.1 - 6.8e-114 379.1 0.3 7.7e-114 379.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EEB07681.1 - 0.00056 19.7 0.0 0.0041 16.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEB07681.1 - 0.16 12.4 0.1 1.1 9.6 0.0 2.3 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB07681.1 - 0.17 12.2 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB07681.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RHH_1 PF01402.21 EEB07681.1 - 0.22 11.5 0.1 5.4 7.1 0.0 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family NAD_binding_8 PF13450.6 EEB07682.1 - 4.8e-15 55.5 0.0 9e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEB07682.1 - 0.00042 20.0 0.5 0.089 12.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EEB07682.1 - 0.0013 18.1 0.1 0.0059 15.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lum_binding PF00677.17 EEB07682.1 - 0.0088 16.0 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Lumazine binding domain Pyr_redox_2 PF07992.14 EEB07682.1 - 0.019 14.2 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB07682.1 - 0.03 14.3 0.1 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding CBS PF00571.28 EEB07683.2 - 1.4e-19 70.2 2.5 8.3e-07 29.4 0.1 4.4 4 0 0 4 4 4 4 CBS domain TCTP PF00838.17 EEB07684.1 - 1.7e-73 246.4 1.7 1.9e-73 246.3 1.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PEX11 PF05648.14 EEB07685.1 - 0.04 13.4 1.5 0.058 12.9 0.4 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) LDB19 PF13002.7 EEB07686.1 - 2e-32 112.5 2.4 3.3e-32 111.8 2.4 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EEB07686.1 - 1.1e-06 28.8 0.2 1.9e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EEB07686.1 - 0.075 13.5 0.2 0.65 10.4 0.1 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Endonuclease_5 PF04493.14 EEB07687.1 - 6e-55 186.0 0.0 7.9e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 EEB07687.1 - 0.0068 15.8 0.3 0.018 14.5 0.1 1.8 3 0 0 3 3 3 1 Protein of unknown function DUF99 Aminotran_5 PF00266.19 EEB07688.1 - 6.1e-40 137.3 0.0 7e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CTP_transf_like PF01467.26 EEB07690.1 - 1.4e-10 41.5 0.0 2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like PIG-S PF10510.9 EEB07691.2 - 1.6e-83 281.3 9.4 2.2e-82 277.6 9.4 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TMEMspv1-c74-12 PF11044.8 EEB07691.2 - 0.64 10.0 3.1 1.4 8.9 3.1 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cyt-b5 PF00173.28 EEB07692.1 - 5.8e-23 80.8 0.0 7.4e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cep57_MT_bd PF06657.13 EEB07693.1 - 4.2e-24 84.8 0.8 4.2e-24 84.8 0.8 4.6 4 1 1 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EEB07693.1 - 4.6e-17 61.9 13.7 4.6e-17 61.9 13.7 2.9 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF4763 PF15960.5 EEB07693.1 - 0.005 16.2 16.1 0.005 16.2 16.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) YjbH PF06082.11 EEB07693.1 - 2.4 6.9 9.4 4.3 6.0 9.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH PK PF00224.21 EEB07694.1 - 1.2e-169 563.7 4.7 1.6e-169 563.3 4.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EEB07694.1 - 4.4e-33 114.0 1.1 1.2e-32 112.6 0.2 2.2 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EEB07694.1 - 6.2e-05 22.2 0.5 0.00021 20.5 0.3 1.9 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EEB07694.1 - 0.014 14.4 0.2 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DnaJ-X PF14308.6 EEB07695.1 - 9.5e-59 198.4 0.1 9.5e-59 198.4 0.1 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EEB07695.1 - 2.7e-26 91.5 3.0 3.5e-26 91.1 1.5 2.1 2 0 0 2 2 2 1 DnaJ domain UPF0242 PF06785.11 EEB07695.1 - 0.024 14.7 1.1 0.044 13.9 1.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5623 PF18536.1 EEB07695.1 - 0.029 14.7 0.3 0.08 13.2 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) TetR_C_6 PF13977.6 EEB07695.1 - 0.22 11.7 6.2 5.7 7.2 2.7 2.9 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal Metal_resist PF13801.6 EEB07696.1 - 7.1 6.8 9.1 2.1 8.6 0.2 3.3 2 2 1 3 3 3 0 Heavy-metal resistance Glyco_hydro_15 PF00723.21 EEB07697.1 - 1.3e-64 218.6 0.0 1.9e-63 214.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 ORC2 PF04084.14 EEB07698.1 - 3.1e-104 348.5 0.2 4.7e-104 347.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 EEB07698.1 - 0.046 13.6 4.3 0.097 12.6 4.3 1.6 1 0 0 1 1 1 0 AT hook motif Ogr_Delta PF04606.12 EEB07698.1 - 2.4 8.2 5.0 0.43 10.6 0.8 1.9 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Cupredoxin_1 PF13473.6 EEB07699.2 - 0.048 13.8 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain Ribosomal_L27e PF01777.18 EEB07700.1 - 7.5e-39 132.0 3.0 1e-38 131.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EEB07700.1 - 3.5e-05 23.6 0.1 9.5e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 KOW motif SepSecS PF05889.13 EEB07700.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Ribosomal_S2 PF00318.20 EEB07701.2 - 4.1e-26 91.6 0.2 2e-13 50.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EEB07701.2 - 5.3e-08 34.1 15.9 1e-07 33.2 15.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PIG-H PF10181.9 EEB07702.1 - 2.6e-20 72.0 0.2 4.1e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component BC10 PF06726.12 EEB07702.1 - 0.054 13.7 2.2 8 6.8 0.0 2.6 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Clat_adaptor_s PF01217.20 EEB07703.1 - 5.1e-51 172.4 2.3 5.6e-51 172.2 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Exo5 PF09810.9 EEB07705.1 - 3e-77 260.6 9.8 2.3e-40 139.3 3.0 3.3 2 1 1 3 3 3 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EEB07705.1 - 0.00038 20.5 0.3 0.013 15.4 0.3 2.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily INCENP_ARK-bind PF03941.15 EEB07706.1 - 2.7e-20 72.1 3.1 2.7e-20 72.1 3.1 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Pan3_PK PF18101.1 EEB07707.1 - 1e-36 126.0 0.1 1.7e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EEB07707.1 - 9.9e-06 25.1 0.4 2.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07707.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PAM2 PF07145.15 EEB07707.1 - 6.2 6.8 10.8 0.14 11.9 1.0 3.3 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Peptidase_S24 PF00717.23 EEB07708.1 - 2.7e-07 30.4 0.1 7.4e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEB07708.1 - 1.1e-06 28.5 0.0 0.0013 18.5 0.0 2.5 1 1 2 3 3 3 2 Signal peptidase, peptidase S26 Ank_4 PF13637.6 EEB07709.1 - 8.1e-15 55.0 3.0 1.6e-06 28.5 0.1 4.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB07709.1 - 2.1e-11 44.3 1.0 0.00025 21.6 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEB07709.1 - 1.1e-09 37.7 5.2 0.0016 18.8 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EEB07709.1 - 2.4e-09 37.2 7.9 0.0071 16.8 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EEB07709.1 - 0.00027 21.2 3.8 0.015 15.7 0.5 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) FPP PF05911.11 EEB07709.1 - 0.00035 18.9 0.5 0.00061 18.1 0.5 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 EEB07709.1 - 0.025 14.3 1.1 0.073 12.8 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Fez1 PF06818.15 EEB07709.1 - 0.06 13.8 4.8 0.15 12.5 4.8 1.6 1 0 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 EEB07709.1 - 0.22 11.0 3.7 0.56 9.7 3.7 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit PilO PF04350.13 EEB07709.1 - 0.57 10.3 3.7 1.3 9.1 3.2 1.9 1 1 0 1 1 1 0 Pilus assembly protein, PilO Spc7 PF08317.11 EEB07709.1 - 5.5 5.8 11.5 0.27 10.1 5.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Vps52 PF04129.12 EEB07710.1 - 1.7e-128 429.6 4.3 2.1e-128 429.3 4.3 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Exo70 PF03081.15 EEB07710.1 - 0.0041 16.2 3.0 0.37 9.8 0.1 2.7 2 1 1 3 3 3 2 Exo70 exocyst complex subunit TolA_bind_tri PF16331.5 EEB07710.1 - 0.046 13.8 0.9 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation ADIP PF11559.8 EEB07710.1 - 0.4 10.8 3.8 12 6.0 0.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding eIF-5a PF01287.20 EEB07711.1 - 3.1e-28 97.7 0.2 4.3e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EEB07711.1 - 0.056 13.5 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 EEB07712.1 - 1.2e-10 40.9 2.3 1.8e-10 40.3 2.3 1.3 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Spc24 PF08286.11 EEB07713.1 - 2.7e-27 95.1 1.5 2.7e-27 95.1 1.5 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Tup_N PF08581.10 EEB07713.1 - 0.059 13.7 1.5 0.059 13.7 1.5 2.3 1 1 1 2 2 2 0 Tup N-terminal Sec2p PF06428.11 EEB07713.1 - 0.41 10.7 11.9 0.14 12.1 2.1 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Prefoldin PF02996.17 EEB07713.1 - 0.58 10.1 8.3 1.3 8.9 1.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 EEB07713.1 - 0.63 10.1 15.5 5.8 6.9 15.6 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EEB07713.1 - 0.74 10.0 8.6 1.5 9.0 8.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 EEB07713.1 - 1.1 9.6 7.3 1.6 9.2 1.5 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 EEB07713.1 - 1.5 8.1 7.5 2.1 7.6 7.5 1.1 1 0 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 EEB07713.1 - 2.1 8.8 6.0 0.67 10.4 1.3 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) B-block_TFIIIC PF04182.12 EEB07714.2 - 1.3e-16 60.5 0.0 3.7e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 EEB07714.2 - 0.0098 15.4 0.9 9.8 5.8 0.1 3.5 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding Myb_DNA-binding PF00249.31 EEB07714.2 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Methyltransf_12 PF08242.12 EEB07715.1 - 4.2e-08 33.8 0.0 7.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB07715.1 - 7e-07 29.9 0.0 1.5e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB07715.1 - 1.3e-06 28.9 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB07715.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB07715.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EEB07715.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DNA_pol_B PF00136.21 EEB07716.1 - 1.5e-149 498.7 0.5 3.5e-149 497.4 0.7 1.5 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEB07716.1 - 4e-92 308.9 0.4 8.6e-92 307.8 0.4 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EEB07716.1 - 4.9e-19 68.6 5.0 1.1e-18 67.4 5.0 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EEB07716.1 - 0.0036 16.2 0.9 0.0054 15.7 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EEB07716.1 - 0.025 14.6 0.1 0.16 11.9 0.1 2.4 1 1 0 1 1 1 0 RNase_H superfamily HemX PF04375.14 EEB07716.1 - 0.035 13.4 0.1 2.8 7.1 0.1 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2660 PF10859.8 EEB07716.1 - 0.089 13.3 0.5 0.27 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) DUF1476 PF07345.11 EEB07716.1 - 0.19 12.1 1.2 20 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta RasGEF PF00617.19 EEB07717.1 - 2.9e-49 167.7 0.1 4e-48 164.0 0.0 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EEB07717.1 - 2.8e-18 66.1 0.1 7.2e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 EEB07717.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 WW domain RrnaAD PF00398.20 EEB07718.1 - 4.8e-66 222.5 0.0 6.2e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EEB07718.1 - 3.8e-07 30.7 0.0 7.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB07718.1 - 3.1e-05 24.5 0.0 6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB07718.1 - 0.00025 21.7 0.0 0.00049 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEB07718.1 - 0.00059 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EEB07718.1 - 0.00059 19.6 0.0 0.00087 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EEB07718.1 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EEB07718.1 - 0.0027 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 EEB07718.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 EEB07718.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.17 EEB07718.1 - 0.016 14.8 0.1 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EEB07718.1 - 0.027 14.3 0.0 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEB07718.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 EEB07718.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.16 EEB07718.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UvrD_C PF13361.6 EEB07719.1 - 8.7e-15 54.9 0.0 2.9e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EEB07719.1 - 9.1e-15 55.0 3.3 1.7e-10 41.0 3.3 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EEB07719.1 - 2.7e-12 47.3 0.0 5.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEB07719.1 - 1.6e-09 37.9 0.1 0.032 14.0 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EEB07719.1 - 1.4e-08 34.4 0.1 1.7e-07 30.9 0.0 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EEB07719.1 - 0.00037 20.3 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EEB07719.1 - 0.0093 15.4 0.1 0.61 9.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 EEB07719.1 - 0.043 13.9 1.9 4.4 7.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain Lung_7-TM_R PF06814.13 EEB07720.1 - 2.4e-38 132.0 18.9 3e-38 131.8 18.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Sigma_reg_N PF13800.6 EEB07720.1 - 0.25 11.7 1.6 6.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Arf PF00025.21 EEB07721.1 - 1.7e-80 268.5 0.1 2e-80 268.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEB07721.1 - 1.7e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEB07721.1 - 2.5e-14 53.1 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EEB07721.1 - 1.3e-13 50.8 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEB07721.1 - 1.3e-12 47.6 1.1 1.4e-08 34.3 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEB07721.1 - 1.3e-09 37.7 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB07721.1 - 3.4e-06 27.1 0.0 5.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEB07721.1 - 0.0069 15.7 0.1 0.0086 15.4 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 EEB07722.2 - 2.1e-50 171.2 0.0 3.5e-48 163.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEB07722.2 - 2.3e-35 120.6 1.8 2.3e-35 120.6 1.8 2.9 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EEB07722.2 - 1.9e-27 95.1 0.3 8.7e-27 93.0 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EEB07722.2 - 2e-18 67.1 0.0 1.3e-08 35.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB07722.2 - 2.4e-13 50.3 0.0 3.1e-09 36.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB07722.2 - 6e-11 43.0 7.7 0.00032 21.1 0.1 4.6 3 2 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EEB07722.2 - 1.1e-07 31.8 0.2 5.1e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EEB07722.2 - 4.6e-07 30.2 5.1 0.0054 17.0 0.0 4.4 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EEB07722.2 - 5.6e-07 30.3 10.2 0.078 13.5 5.8 3.6 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 EEB07722.2 - 1.3e-06 28.5 0.2 0.08 12.8 0.0 3.4 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 EEB07722.2 - 3.5e-06 26.9 0.1 0.082 12.6 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EEB07722.2 - 3.7e-06 26.6 0.0 0.039 13.5 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 EEB07722.2 - 5.5e-06 26.5 4.4 0.054 13.4 0.1 4.1 3 2 0 3 3 2 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EEB07722.2 - 1.6e-05 25.0 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EEB07722.2 - 4.9e-05 23.9 0.6 0.23 12.0 0.0 3.6 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 EEB07722.2 - 6.6e-05 23.3 0.1 1.1 9.7 0.1 3.5 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EEB07722.2 - 7.1e-05 23.4 0.1 0.71 10.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EEB07722.2 - 0.00011 21.6 1.2 0.28 10.5 0.0 3.7 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EEB07722.2 - 0.00013 21.9 0.8 1 9.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase TsaE PF02367.17 EEB07722.2 - 0.0005 20.1 1.5 0.96 9.5 0.0 2.8 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEB07722.2 - 0.00063 19.5 1.8 0.3 10.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EEB07722.2 - 0.00065 19.7 0.3 2.6 8.0 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 EEB07722.2 - 0.00075 19.3 1.4 0.34 10.6 0.0 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 EEB07722.2 - 0.002 18.3 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EEB07722.2 - 0.0027 17.3 0.4 0.18 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EEB07722.2 - 0.0033 17.3 2.0 2.9 7.6 0.0 3.9 4 1 1 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB07722.2 - 0.0038 16.9 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EEB07722.2 - 0.0042 16.8 0.0 0.91 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEB07722.2 - 0.005 17.1 3.8 3.6 7.8 0.0 4.3 4 1 1 5 5 4 1 AAA domain SRP54 PF00448.22 EEB07722.2 - 0.0096 15.6 0.1 2.9 7.5 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.6 EEB07722.2 - 0.012 15.5 0.2 0.33 10.7 0.0 3.0 2 1 0 2 2 2 0 DNA polymerase III, delta subunit DUF815 PF05673.13 EEB07722.2 - 0.013 14.7 0.2 4.2 6.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 EEB07722.2 - 0.024 13.5 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EEB07722.2 - 0.027 13.7 0.1 1.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.17 EEB07722.2 - 0.028 14.5 5.9 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EEB07722.2 - 0.034 13.9 1.3 2.8 7.6 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Syntaxin_2 PF14523.6 EEB07722.2 - 0.044 14.1 4.8 0.15 12.4 4.8 1.9 1 0 0 1 1 1 0 Syntaxin-like protein NB-ARC PF00931.22 EEB07722.2 - 0.067 12.4 1.2 1.4 8.0 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.9 EEB07722.2 - 0.07 12.9 0.0 0.78 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EEB07722.2 - 0.083 13.2 3.3 9.3 6.6 0.0 4.0 3 1 0 3 3 3 0 AAA domain Torsin PF06309.11 EEB07722.2 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_31 PF13614.6 EEB07722.2 - 0.17 11.8 0.6 18 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EEB07722.2 - 0.19 11.8 0.3 24 5.0 0.0 3.5 3 1 0 3 3 2 0 50S ribosome-binding GTPase ALMT PF11744.8 EEB07722.2 - 0.47 9.2 1.8 0.78 8.5 1.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_33 PF13671.6 EEB07722.2 - 0.48 10.6 7.6 15 5.8 0.3 4.6 4 2 0 4 4 4 0 AAA domain HAUS2 PF15003.6 EEB07722.2 - 0.89 9.3 13.4 0.027 14.2 3.7 2.7 2 1 1 3 3 2 0 HAUS augmin-like complex subunit 2 DUF724 PF05266.14 EEB07722.2 - 1.4 8.7 8.6 2.9 7.7 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 EEB07722.2 - 1.4 9.6 6.6 5.3 7.7 6.6 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Prefoldin PF02996.17 EEB07722.2 - 5.2 7.0 13.3 1.6 8.6 0.1 4.2 3 1 2 5 5 3 0 Prefoldin subunit ERO1 PF04137.15 EEB07723.1 - 1.6e-113 379.5 0.5 1.9e-113 379.3 0.5 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Rad10 PF03834.14 EEB07724.2 - 1.1e-47 160.7 0.0 1.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EEB07724.2 - 0.00047 20.7 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EEB07724.2 - 0.0006 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HRDC PF00570.23 EEB07724.2 - 0.0042 17.1 0.2 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 HRDC domain HHH_3 PF12836.7 EEB07724.2 - 0.035 14.4 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif FANCI_HD1 PF14679.6 EEB07724.2 - 0.05 13.6 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 FANCI helical domain 1 HHH PF00633.23 EEB07724.2 - 0.082 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 EEB07725.2 - 8.8e-61 201.7 0.3 8.5e-21 73.6 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 EEB07725.2 - 5.2e-05 22.8 20.2 5.2e-05 22.8 20.2 2.3 2 0 0 2 2 2 1 SDA1 BSP_II PF05432.11 EEB07725.2 - 0.00017 21.4 21.4 0.00017 21.4 21.4 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) RRM_5 PF13893.6 EEB07725.2 - 0.0052 16.4 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EEB07725.2 - 0.027 14.3 1.2 9.3 6.0 0.1 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EEB07725.2 - 0.04 13.9 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Zip PF02535.22 EEB07725.2 - 0.49 9.6 11.6 0.0077 15.5 3.8 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter BOP1NT PF08145.12 EEB07726.1 - 6.8e-95 317.9 2.9 1.3e-94 316.9 2.9 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EEB07726.1 - 2.3e-23 82.0 12.5 3.6e-07 30.8 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07726.1 - 2.2e-07 31.1 0.2 0.97 9.8 0.1 5.8 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EEB07726.1 - 0.0018 16.7 0.0 0.0039 15.6 0.0 1.5 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz LIM PF00412.22 EEB07727.2 - 6e-28 96.8 36.1 6e-12 45.6 8.1 3.2 3 0 0 3 3 3 3 LIM domain Asn_synthase PF00733.21 EEB07728.1 - 1e-13 51.7 0.9 1.3e-08 34.9 0.7 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EEB07728.1 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEB07728.1 - 1.2e-09 38.5 0.0 2.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEB07728.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein VPS9 PF02204.18 EEB07729.1 - 1.5e-29 102.3 0.2 3.4e-29 101.1 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EEB07729.1 - 1.8e-13 50.6 0.9 1.8e-13 50.6 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 EEB07729.1 - 3.5e-10 39.4 0.0 6.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain CDC4_D PF16856.5 EEB07729.1 - 0.045 13.6 0.8 0.13 12.1 0.8 1.8 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain MFS_1 PF07690.16 EEB07730.2 - 6.3e-21 74.7 53.3 1.5e-19 70.2 51.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB07730.2 - 1.1e-12 47.2 26.3 1.5e-12 46.7 26.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB07730.2 - 7e-06 25.2 49.7 8.5e-05 21.6 13.1 4.0 3 1 1 4 4 4 3 Sugar (and other) transporter DEAD PF00270.29 EEB07731.1 - 5.1e-44 150.1 0.3 1.2e-43 148.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07731.1 - 2.2e-31 108.5 1.7 6.5e-29 100.5 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07731.1 - 2.9e-07 30.6 1.8 5.9e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EEB07731.1 - 0.0018 17.6 0.0 0.0018 17.6 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EEB07731.1 - 0.0097 16.2 1.7 0.041 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain UTP25 PF06862.12 EEB07731.1 - 0.038 12.8 0.3 0.28 9.9 0.1 2.2 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SWIRM-assoc_2 PF16496.5 EEB07731.1 - 0.12 11.2 10.0 0.2 10.5 10.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Presenilin PF01080.17 EEB07731.1 - 7.5 5.2 8.3 13 4.5 8.3 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_L33 PF00471.20 EEB07732.1 - 8e-07 29.4 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 RTT107_BRCT_5 PF16770.5 EEB07733.1 - 1.3e-28 98.8 2.8 1.3e-22 79.5 0.1 4.4 5 0 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EEB07733.1 - 1.6e-23 82.8 6.3 9e-10 38.8 0.0 6.2 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEB07733.1 - 4.2e-20 71.4 2.0 8.8e-13 48.0 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 EEB07733.1 - 1.2e-14 54.5 0.4 0.02 15.3 0.0 5.4 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EEB07733.1 - 7.8e-07 29.1 0.4 0.36 10.9 0.0 4.1 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EEB07733.1 - 9.1e-06 25.9 3.1 0.53 10.6 0.2 5.1 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain WI12 PF07107.11 EEB07733.1 - 0.015 15.4 0.1 0.067 13.3 0.0 2.0 2 0 0 2 2 2 0 Wound-induced protein WI12 JAMP PF05571.12 EEB07733.1 - 0.03 14.0 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein Hydrolase_6 PF13344.6 EEB07733.1 - 0.069 13.3 0.0 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EEB07734.1 - 5.9e-69 232.4 0.1 2.8e-68 230.1 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07734.1 - 3.5e-36 124.8 0.0 1.3e-35 123.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EEB07734.1 - 1.3e-16 60.1 0.0 2.5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EEB07734.1 - 4.3e-08 32.5 0.0 8.9e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEB07734.1 - 2e-07 30.6 0.2 4.9e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEB07734.1 - 1.9e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEB07734.1 - 0.00013 22.0 0.1 0.071 13.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 EEB07734.1 - 0.0028 17.3 0.2 0.0047 16.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EEB07734.1 - 0.0054 16.3 0.1 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EEB07734.1 - 0.021 13.6 0.8 0.03 13.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase TFIIF_alpha PF05793.12 EEB07734.1 - 2.5 6.6 5.9 4.7 5.7 5.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lectin_leg-like PF03388.13 EEB07735.1 - 1.4e-28 99.8 0.1 2.2e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Tropomyosin PF00261.20 EEB07735.1 - 0.025 14.0 4.1 0.041 13.2 4.1 1.2 1 0 0 1 1 1 0 Tropomyosin Serine_rich PF08824.10 EEB07735.1 - 0.12 12.4 1.5 0.2 11.7 1.5 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF4795 PF16043.5 EEB07735.1 - 0.17 11.5 0.2 0.17 11.5 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EEB07735.1 - 0.23 12.1 2.7 1 10.0 0.6 2.3 1 1 0 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 EEB07735.1 - 0.32 10.5 2.6 0.46 10.0 2.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup54 PF13874.6 EEB07735.1 - 0.42 10.7 4.7 2.5 8.2 1.1 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 BLOC1_2 PF10046.9 EEB07735.1 - 0.83 10.0 8.0 2.5 8.4 0.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 EEB07735.1 - 1.8 8.6 6.2 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Ribosomal_L23eN PF03939.13 EEB07736.1 - 1.5e-19 69.9 7.0 1.5e-19 69.9 7.0 1.8 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EEB07736.1 - 1.8e-15 57.1 5.4 1.8e-15 57.1 5.4 2.6 2 2 0 2 2 2 1 Ribosomal protein L23 HMGL-like PF00682.19 EEB07737.1 - 1.4e-76 257.6 0.0 2.3e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EEB07737.1 - 5.4e-25 87.8 0.0 8.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain TLC PF03219.14 EEB07737.1 - 0.076 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter TRAM_LAG1_CLN8 PF03798.16 EEB07738.2 - 1e-35 123.3 31.7 1e-35 123.3 31.7 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EEB07738.2 - 1.7e-19 69.2 0.1 1.7e-19 69.2 0.1 2.4 2 0 0 2 2 2 1 TRAM1-like protein LSM PF01423.22 EEB07739.2 - 2.8e-22 78.2 0.0 3.1e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB07739.2 - 0.013 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain SYF2 PF08231.12 EEB07740.2 - 1.3e-47 162.1 24.2 1.3e-47 162.1 24.2 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Spore_III_AF PF09581.10 EEB07740.2 - 1.9 8.5 9.7 0.32 11.0 4.8 1.8 1 1 2 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Sel1 PF08238.12 EEB07741.1 - 1.8e-10 41.1 6.3 0.00041 20.9 0.0 3.9 4 0 0 4 4 4 2 Sel1 repeat TPR_7 PF13176.6 EEB07741.1 - 0.0029 17.5 0.1 0.012 15.6 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEB07741.1 - 0.013 15.3 0.8 0.013 15.3 0.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FtsK_gamma PF09397.10 EEB07741.1 - 0.045 13.6 0.1 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Ftsk gamma domain TPR_8 PF13181.6 EEB07741.1 - 0.057 13.6 0.7 0.45 10.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEB07741.1 - 0.096 13.0 1.5 0.22 11.9 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sin3a_C PF16879.5 EEB07742.1 - 2.7e-76 257.1 0.0 2.7e-76 257.1 0.0 3.9 5 1 1 6 6 6 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EEB07742.1 - 3.6e-37 126.4 0.1 3.6e-37 126.4 0.1 3.3 3 0 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.21 EEB07742.1 - 4.8e-37 125.8 8.6 3e-16 59.3 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat HlyIII PF03006.20 EEB07743.1 - 3.5e-66 223.1 18.2 4.2e-66 222.9 18.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3352 PF11832.8 EEB07743.1 - 0.13 10.9 0.2 0.17 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) DUF1129 PF06570.11 EEB07743.1 - 2.1 7.8 6.8 0.39 10.2 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 EEB07743.1 - 3.9 7.1 6.6 5 6.8 2.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dynamin_M PF01031.20 EEB07744.1 - 4.7e-99 331.2 0.0 9.5e-99 330.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EEB07744.1 - 3.7e-54 183.3 0.6 7.8e-54 182.2 0.1 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EEB07744.1 - 2.9e-29 101.1 4.9 7.6e-29 99.7 4.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEB07744.1 - 0.00028 20.9 0.4 0.0039 17.2 0.2 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Glu_dehyd_C PF16912.5 EEB07744.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF5130 PF17174.4 EEB07744.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) AAA_16 PF13191.6 EEB07744.1 - 0.11 12.9 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NOB1_Zn_bind PF08772.11 EEB07744.1 - 0.15 12.2 0.0 0.5 10.6 0.0 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like AAA_28 PF13521.6 EEB07744.1 - 0.16 12.2 0.4 1.5 9.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain Med7 PF05983.11 EEB07745.1 - 4.8e-67 225.7 4.1 7.2e-67 225.2 4.1 1.3 1 0 0 1 1 1 1 MED7 protein MPS2 PF17060.5 EEB07745.1 - 0.013 14.8 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 CENP-H PF05837.12 EEB07745.1 - 8.4 6.9 8.4 0.44 11.0 0.4 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 EEB07745.1 - 9.3 6.3 14.1 0.18 11.8 1.0 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 EEB07745.1 - 9.6 6.1 7.7 1.5 8.6 1.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Lyase_1 PF00206.20 EEB07746.1 - 1.5e-22 80.4 0.0 2.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EEB07746.1 - 8.1e-16 58.3 0.0 2.4e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus LON_substr_bdg PF02190.16 EEB07747.1 - 3.5e-25 89.1 0.0 5.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EEB07747.1 - 2.6e-14 52.7 22.4 3.4e-13 49.2 9.9 3.1 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB07747.1 - 5.2e-11 42.5 21.0 1.3e-05 25.3 8.0 3.5 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EEB07747.1 - 7e-10 38.6 20.1 1.5e-08 34.3 5.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB07747.1 - 1.7e-09 37.5 21.4 4.3e-07 29.9 7.2 2.9 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EEB07747.1 - 1.9e-09 37.2 21.7 3.9e-07 29.8 9.2 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB07747.1 - 1.1e-08 34.8 21.8 5.6e-08 32.6 7.0 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 EEB07747.1 - 1.4e-08 34.9 7.9 1.4e-08 34.9 7.9 3.4 3 0 0 3 3 3 2 Ring finger domain Prok-RING_4 PF14447.6 EEB07747.1 - 4.5e-05 23.2 23.5 0.00031 20.5 7.6 2.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 U-box PF04564.15 EEB07747.1 - 0.001 19.2 0.1 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 U-box domain zf-RING_4 PF14570.6 EEB07747.1 - 0.0029 17.4 5.3 0.0029 17.4 5.3 3.2 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EEB07747.1 - 0.0036 17.5 4.5 0.0036 17.5 4.5 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EEB07747.1 - 0.0068 16.5 19.1 0.023 14.8 6.1 3.0 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf_UBZ PF18439.1 EEB07747.1 - 0.024 14.2 1.4 2.3 7.9 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PX PF00787.24 EEB07748.2 - 6.3e-20 71.3 0.3 1.8e-19 69.8 0.3 1.8 1 0 0 1 1 1 1 PX domain She9_MDM33 PF05546.11 EEB07748.2 - 0.059 13.2 2.7 0.1 12.4 0.8 2.2 2 0 0 2 2 2 0 She9 / Mdm33 family Alk_phosphatase PF00245.20 EEB07749.1 - 9.6e-101 337.7 0.0 1.2e-100 337.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EEB07749.1 - 8.8e-06 25.3 0.5 3.2e-05 23.4 0.0 2.2 4 0 0 4 4 4 1 Metalloenzyme superfamily SeleniumBinding PF11524.8 EEB07749.1 - 0.16 12.5 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein Metallophos PF00149.28 EEB07750.1 - 1.2e-31 110.8 0.0 2e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EEB07750.1 - 4.1e-29 100.7 0.0 8.2e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 EEB07750.1 - 7.9e-20 69.3 9.5 6.5e-07 29.0 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEB07750.1 - 2.6e-19 68.2 11.1 1.5e-08 34.1 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEB07750.1 - 7.8e-15 54.3 9.3 8.7e-11 41.3 0.1 3.7 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 EEB07750.1 - 2.5e-10 40.0 3.6 4.5e-05 23.5 0.1 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEB07750.1 - 3.8e-10 39.2 4.3 0.00061 19.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB07750.1 - 1.2e-06 28.9 0.7 0.023 15.2 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEB07750.1 - 1.3e-06 29.0 0.3 9.5e-05 23.0 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEB07750.1 - 1.2e-05 25.7 0.3 0.47 11.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB07750.1 - 0.00022 21.4 0.3 0.0084 16.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEB07750.1 - 0.00022 21.3 0.0 0.23 11.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEB07750.1 - 0.00098 19.0 0.3 0.22 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB07750.1 - 0.027 15.1 2.1 3.9 8.3 0.4 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 EEB07750.1 - 0.037 13.2 0.2 0.3 10.3 0.2 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_18 PF13512.6 EEB07750.1 - 0.09 12.9 0.7 0.21 11.7 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 EEB07750.1 - 0.19 12.0 0.1 6.9 7.0 0.0 2.3 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 3Beta_HSD PF01073.19 EEB07751.1 - 8.8e-64 215.2 0.0 1e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEB07751.1 - 4.5e-30 104.9 0.0 5.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEB07751.1 - 2.2e-18 66.7 0.0 3.2e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EEB07751.1 - 2.4e-16 59.7 0.0 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEB07751.1 - 6.5e-13 49.0 0.0 8.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EEB07751.1 - 1.3e-08 34.3 0.1 7.4e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EEB07751.1 - 2.5e-08 33.4 0.1 6.6e-07 28.8 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EEB07751.1 - 0.00017 21.9 0.0 0.00028 21.2 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EEB07751.1 - 0.0016 18.4 0.0 0.067 13.1 0.0 2.2 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 EEB07751.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 EEB07751.1 - 0.025 14.2 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family FtsJ PF01728.19 EEB07751.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Aha1_N PF09229.11 EEB07751.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal GTP_EFTU PF00009.27 EEB07752.2 - 7.1e-34 117.0 1.7 3.6e-32 111.5 1.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEB07752.2 - 5e-17 62.0 0.3 1.2e-16 60.8 0.3 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EEB07752.2 - 3.6e-10 39.9 0.1 9.6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB07752.2 - 6.6e-05 22.9 0.0 0.2 11.5 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EEB07752.2 - 0.00059 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEB07752.2 - 0.0035 16.9 0.0 0.012 15.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EEB07752.2 - 0.0037 16.7 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EEB07752.2 - 0.0039 17.3 0.7 0.26 11.3 0.0 2.8 2 1 1 3 3 3 1 Dynamin family PduV-EutP PF10662.9 EEB07752.2 - 0.0044 16.8 0.1 0.019 14.7 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EEB07752.2 - 0.043 14.3 0.0 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU_D4 PF14578.6 EEB07752.2 - 0.08 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 1 0 Elongation factor Tu domain 4 AAA_29 PF13555.6 EEB07752.2 - 0.094 12.5 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgoN PF16486.5 EEB07752.2 - 0.1 13.2 0.1 0.43 11.2 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain of argonaute Ank_3 PF13606.6 EEB07753.1 - 1.2e-07 31.4 1.9 0.0054 17.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EEB07753.1 - 3.2e-07 30.8 0.1 6.1e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB07753.1 - 8.6e-07 29.1 1.3 4.9e-06 26.7 0.3 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EEB07753.1 - 1.4e-06 28.5 0.5 0.029 14.8 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EEB07753.1 - 1.4e-06 28.7 0.1 3e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Pkinase PF00069.25 EEB07754.1 - 2.1e-76 256.8 0.0 2.4e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07754.1 - 1.3e-39 136.0 0.0 1.7e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07754.1 - 1.5e-08 34.3 0.0 2.6e-07 30.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB07754.1 - 3e-05 23.0 0.0 6.9e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EEB07754.1 - 3e-05 23.6 0.1 7.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EEB07754.1 - 9.5e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1186 PF06685.11 EEB07754.1 - 0.05 13.0 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) zinc_ribbon_13 PF09855.9 EEB07754.1 - 0.1 12.8 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) APH PF01636.23 EEB07754.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_9 PF13426.7 EEB07755.1 - 2.7e-19 69.4 0.0 1.8e-15 57.0 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EEB07755.1 - 2.8e-09 37.0 0.0 0.044 13.8 0.0 4.4 3 2 0 4 4 4 3 PAS fold PAS_3 PF08447.12 EEB07755.1 - 1.4e-08 34.9 0.0 0.03 14.6 0.1 4.1 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 EEB07755.1 - 0.0051 17.1 0.0 5.4 7.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold Ribosomal_S13 PF00416.22 EEB07756.1 - 3.3e-53 179.4 2.5 3.8e-53 179.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EEB07756.1 - 0.009 14.8 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Period_C PF12114.8 EEB07756.1 - 0.009 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Period protein 2/3C-terminal region HHH_6 PF14579.6 EEB07756.1 - 0.013 15.7 0.5 0.091 13.0 0.1 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 EEB07756.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) PWI PF01480.17 EEB07757.1 - 2.4e-30 104.6 0.2 6.3e-30 103.3 0.2 1.7 1 0 0 1 1 1 1 PWI domain Pcc1 PF09341.10 EEB07758.2 - 1.5e-21 76.3 0.1 1.7e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 SHE3 PF17078.5 EEB07759.1 - 0.00094 19.0 20.7 0.00094 19.0 20.7 2.4 2 1 1 3 3 3 1 SWI5-dependent HO expression protein 3 DUF1216 PF06746.11 EEB07759.1 - 0.011 15.7 1.3 0.011 15.7 1.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1216) DUF4400 PF14348.6 EEB07759.1 - 0.2 11.1 0.2 0.39 10.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Ca_chan_IQ PF08763.11 EEB07759.1 - 1 9.6 0.0 1 9.6 0.0 4.1 4 2 1 5 5 5 0 Voltage gated calcium channel IQ domain Tctex-1 PF03645.13 EEB07759.1 - 1 9.6 6.1 5.9 7.2 1.5 2.7 2 1 0 2 2 2 0 Tctex-1 family NOA36 PF06524.12 EEB07759.1 - 1.7 7.9 11.4 4 6.7 11.4 1.7 1 0 0 1 1 1 0 NOA36 protein Baculo_PEP_C PF04513.12 EEB07759.1 - 2.9 7.9 17.3 0.78 9.8 0.5 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EEB07759.1 - 8.5 5.9 18.1 0.33 10.5 1.1 3.5 3 1 1 4 4 4 0 fzo-like conserved region DUF3453 PF11935.8 EEB07760.2 - 4.3e-45 154.1 0.0 1.1e-44 152.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) MMS19_C PF12460.8 EEB07761.1 - 2.5e-79 267.4 17.5 2.5e-79 267.4 17.5 4.2 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EEB07761.1 - 1.9e-74 250.5 8.9 1.6e-73 247.5 0.7 3.7 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EEB07761.1 - 1.8e-08 34.7 5.7 0.0012 19.3 0.5 5.7 4 2 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 EEB07761.1 - 9.5e-06 25.9 3.4 0.0041 17.5 0.7 4.6 3 1 1 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EEB07761.1 - 0.0012 19.3 0.0 0.17 12.5 0.0 3.6 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.8 EEB07761.1 - 0.1 13.2 0.2 2.1 9.0 0.0 2.9 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 EEB07761.1 - 0.21 12.0 17.8 0.83 10.1 0.1 6.5 7 0 0 7 7 7 0 HEAT repeat SPC25 PF06703.11 EEB07762.1 - 4.8e-25 88.2 3.6 5.5e-25 88.0 3.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Methyltransf_16 PF10294.9 EEB07763.1 - 0.018 14.8 0.4 0.54 10.0 0.0 2.8 3 0 0 3 3 3 0 Lysine methyltransferase Methyltransf_23 PF13489.6 EEB07763.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Actin PF00022.19 EEB07764.1 - 2.8e-28 98.7 0.0 3.1e-26 91.9 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EEB07764.1 - 0.0042 16.0 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EEB07764.1 - 0.0074 16.7 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 1 Cell division protein FtsA Ribosomal_S19 PF00203.21 EEB07765.1 - 6.6e-34 115.6 0.3 1.2e-33 114.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 EEB07766.1 - 1.8e-24 86.1 17.3 2.1e-24 85.9 17.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ATP19 PF11022.8 EEB07766.1 - 0.35 11.3 2.6 14 6.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase subunit K SNF2_N PF00176.23 EEB07768.2 - 2.5e-64 217.2 3.8 2.5e-64 217.2 3.8 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.6 EEB07768.2 - 4.7e-51 172.7 18.9 4.7e-51 172.7 18.9 5.1 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 EEB07768.2 - 2.6e-17 63.1 0.0 7.8e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB07768.2 - 6.8e-08 32.7 0.0 6.8e-08 32.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEB07768.2 - 0.0019 18.0 0.0 0.0082 15.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RskA PF10099.9 EEB07768.2 - 2.3 8.5 23.6 6.1 7.1 23.6 1.7 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SET PF00856.28 EEB07769.2 - 3.8e-17 63.2 0.3 3.8e-17 63.2 0.3 3.3 2 2 0 2 2 2 1 SET domain SRI PF08236.11 EEB07769.2 - 3.4e-15 56.0 1.8 3.4e-15 56.0 1.8 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 EEB07769.2 - 1.6e-14 53.6 7.5 1.6e-14 53.6 7.5 2.5 2 0 0 2 2 2 1 AWS domain RNR_inhib PF08591.10 EEB07770.2 - 1.2e-07 33.0 0.3 2.5e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor DUF3235 PF11574.8 EEB07770.2 - 0.079 13.8 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) YcbB PF08664.10 EEB07770.2 - 0.1 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 YcbB domain DUF4208 PF13907.6 EEB07770.2 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) HSP70 PF00012.20 EEB07771.1 - 3.7e-60 203.8 4.5 1.3e-59 201.9 4.5 1.8 1 1 0 1 1 1 1 Hsp70 protein RPW8 PF05659.11 EEB07771.1 - 0.058 13.1 0.9 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FGGY_C PF02782.16 EEB07771.1 - 0.084 12.6 0.1 0.66 9.7 0.1 2.5 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain ArlS_N PF18719.1 EEB07771.1 - 0.15 12.3 1.6 0.74 10.0 0.3 2.6 1 1 2 3 3 3 0 ArlS sensor domain Amino_oxidase PF01593.24 EEB07772.1 - 9.4e-29 101.0 0.0 1.1e-28 100.8 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEB07772.1 - 7.1e-12 45.4 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEB07772.1 - 6.5e-10 39.1 0.4 5e-06 26.3 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEB07772.1 - 1.2e-06 28.0 0.1 0.00061 19.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEB07772.1 - 2.8e-05 23.5 0.1 5.2e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EEB07772.1 - 0.00028 21.4 0.3 0.66 10.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEB07772.1 - 0.0035 16.5 0.2 0.0063 15.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EEB07772.1 - 0.0038 16.4 0.2 0.074 12.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EEB07772.1 - 0.0041 16.5 0.2 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 EEB07772.1 - 0.0069 15.2 0.1 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 MCRA family HI0933_like PF03486.14 EEB07772.1 - 0.017 13.8 0.1 3.4 6.3 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 EEB07772.1 - 0.021 13.7 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Mid1 PF12929.7 EEB07773.1 - 9.4e-111 371.0 10.9 1.2e-110 370.7 10.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EEB07773.1 - 0.0021 18.7 8.0 0.015 15.9 5.5 2.7 2 1 0 2 2 2 1 Fz domain Pkinase PF00069.25 EEB07774.1 - 1.4e-66 224.5 0.1 2.1e-66 224.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07774.1 - 2.2e-52 177.9 0.0 3.3e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EEB07774.1 - 1.3e-15 57.5 0.0 2.9e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EEB07774.1 - 5.5e-08 33.3 0.2 1.2e-07 32.2 0.2 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EEB07774.1 - 6.1e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEB07774.1 - 0.0002 20.3 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EEB07774.1 - 0.0008 18.4 0.2 0.0014 17.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEB07774.1 - 0.0017 17.8 0.7 0.003 16.9 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB07774.1 - 0.043 13.7 0.3 0.12 12.2 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNaseH_like PF04308.12 EEB07774.1 - 0.16 11.9 0.6 21 5.0 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease H-like DEAD PF00270.29 EEB07775.1 - 2.1e-44 151.4 0.1 3.4e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB07775.1 - 9.1e-34 116.1 0.1 1.5e-32 112.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEB07775.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEB07775.1 - 0.0037 17.3 0.0 0.0084 16.1 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEB07775.1 - 0.0045 17.3 0.0 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 EEB07775.1 - 0.016 14.0 0.0 0.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EEB07775.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TrkH PF02386.16 EEB07777.1 - 5.2e-136 454.0 2.9 5.2e-136 454.0 2.9 1.8 2 0 0 2 2 2 1 Cation transport protein CCD48 PF15799.5 EEB07777.1 - 0.057 11.7 0.0 0.083 11.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Neur_chan_memb PF02932.16 EEB07777.1 - 0.97 9.4 7.9 0.065 13.3 1.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Phage_holin_3_6 PF07332.11 EEB07777.1 - 1.3 9.1 5.5 0.57 10.2 0.1 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ELO PF01151.18 EEB07778.1 - 6.6e-59 199.4 22.9 8.6e-59 199.1 22.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family YwiC PF14256.6 EEB07778.1 - 0.5 10.7 13.1 0.59 10.4 4.8 3.1 3 0 0 3 3 3 0 YwiC-like protein GCP5-Mod21 PF14609.6 EEB07779.1 - 2.7e-284 944.6 10.3 3.8e-282 937.5 10.3 2.0 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 NDK PF00334.19 EEB07780.1 - 7.1e-57 191.2 0.0 8e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CBM65_1 PF18259.1 EEB07781.1 - 0.19 11.9 0.8 1.2 9.3 0.4 2.1 2 0 0 2 2 2 0 Carbohydrate binding module 65 domain 1 CTP_transf_like PF01467.26 EEB07782.2 - 1.1e-30 106.7 0.0 1.8e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_L14e PF01929.17 EEB07783.1 - 1.5e-32 111.9 3.8 2.2e-32 111.4 3.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 ubiquitin PF00240.23 EEB07784.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EEB07784.1 - 7e-32 109.1 12.1 1.1e-31 108.5 12.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EEB07784.1 - 1.9e-16 59.6 0.7 3e-16 59.0 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB07784.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB07784.1 - 0.0034 17.7 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB07784.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB07784.1 - 0.0065 16.6 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EEB07784.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EEB07784.1 - 0.026 15.1 0.1 0.03 14.9 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EEB07784.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Ribosomal_S26e PF01283.19 EEB07786.1 - 8.4e-55 183.8 8.5 9.9e-55 183.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 EEB07786.1 - 0.1 13.2 2.7 0.55 10.9 2.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain ParA PF10609.9 EEB07787.2 - 1.3e-94 316.3 0.0 1.7e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase WD40 PF00400.32 EEB07787.2 - 7.7e-36 121.5 20.3 6.5e-09 36.3 0.5 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07787.2 - 2.4e-19 69.4 2.6 3.2e-05 24.1 0.0 5.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain CbiA PF01656.23 EEB07787.2 - 1.6e-06 28.2 0.0 5e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain eIF2A PF08662.11 EEB07787.2 - 0.0009 19.2 0.1 0.16 11.9 0.0 2.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A AAA_31 PF13614.6 EEB07787.2 - 0.0033 17.4 0.1 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain Ge1_WD40 PF16529.5 EEB07787.2 - 0.0034 16.4 0.2 3.4 6.5 0.1 3.2 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ArsA_ATPase PF02374.15 EEB07787.2 - 0.0074 15.5 0.1 0.021 14.0 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EEB07787.2 - 0.0083 15.4 0.0 0.031 13.6 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ IKI3 PF04762.12 EEB07787.2 - 0.014 13.4 0.1 0.032 12.2 0.1 1.5 1 1 0 1 1 1 0 IKI3 family AAA_25 PF13481.6 EEB07787.2 - 0.055 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EEB07787.2 - 0.11 11.6 0.4 0.55 9.4 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Coatomer_WDAD PF04053.14 EEB07787.2 - 0.18 10.8 1.6 1.7 7.6 1.6 2.2 1 1 0 1 1 1 0 Coatomer WD associated region RsgA_GTPase PF03193.16 EEB07787.2 - 0.19 11.7 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Porphobil_deam PF01379.20 EEB07788.1 - 8.8e-68 227.8 0.0 1.2e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EEB07788.1 - 1.2e-18 67.2 0.1 2.1e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1327 PF07041.11 EEB07788.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) Plavaka PF18759.1 EEB07788.1 - 0.23 10.6 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Plavaka transposase PhoLip_ATPase_C PF16212.5 EEB07789.1 - 9.6e-74 248.3 23.0 9.6e-74 248.3 23.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEB07789.1 - 4.3e-19 68.0 0.7 1.1e-18 66.7 0.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEB07789.1 - 3.4e-11 43.1 0.0 7.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEB07789.1 - 6.4e-06 26.6 0.1 0.043 14.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEB07789.1 - 0.0092 15.5 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEB07789.1 - 0.01 15.6 0.5 0.02 14.6 0.5 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Maf1 PF09174.10 EEB07790.2 - 5.5e-55 186.2 0.8 6.5e-55 186.0 0.8 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF1754 PF08555.10 EEB07791.1 - 2.2e-07 31.6 22.9 2.2e-07 31.6 22.9 1.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Tox-GHH PF15636.6 EEB07791.1 - 0.087 12.8 3.2 0.16 12.0 3.2 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TMCO5 PF14992.6 EEB07791.1 - 0.84 9.2 8.3 0.97 9.0 8.3 1.0 1 0 0 1 1 1 0 TMCO5 family NPR3 PF03666.13 EEB07791.1 - 9.4 4.9 9.4 11 4.7 9.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 JAB PF01398.21 EEB07792.1 - 3.9e-34 117.2 0.3 2e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEB07792.1 - 2.3e-12 47.3 0.7 4.2e-12 46.5 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EEB07792.1 - 7.9e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GCV_T PF01571.21 EEB07793.1 - 1.3e-85 286.8 0.0 1.6e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EEB07793.1 - 4e-24 84.3 0.3 7.4e-24 83.5 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain MlaD PF02470.20 EEB07793.1 - 0.14 12.5 0.2 0.42 10.9 0.2 1.8 1 0 0 1 1 1 0 MlaD protein PS_Dcarbxylase PF02666.15 EEB07794.1 - 4.5e-58 196.1 0.0 7.5e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EEB07794.1 - 4.3e-18 65.5 0.1 2e-15 56.9 0.0 3.0 2 0 0 2 2 2 2 C2 domain NT-C2 PF10358.9 EEB07794.1 - 0.0037 17.0 2.3 0.31 10.7 0.0 4.2 4 1 0 4 4 4 1 N-terminal C2 in EEIG1 and EHBP1 proteins Glycos_transf_2 PF00535.26 EEB07795.1 - 8.8e-35 120.0 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEB07795.1 - 4.1e-14 53.0 0.0 5.2e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EEB07795.1 - 5.9e-05 22.7 0.0 7.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EEB07795.1 - 0.00063 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 EEB07795.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF4471 PF14740.6 EEB07795.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) S10_plectin PF03501.15 EEB07796.1 - 3.2e-44 148.9 0.1 3.9e-44 148.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 EEB07797.1 - 7.5e-39 133.2 0.2 1.5e-38 132.3 0.2 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain AAA PF00004.29 EEB07798.1 - 3.4e-47 160.2 0.0 9.5e-41 139.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB07798.1 - 1.1e-10 41.1 1.1 3.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 EEB07798.1 - 4.5e-08 33.4 0.0 1.8e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEB07798.1 - 5.6e-06 26.2 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EEB07798.1 - 0.00056 20.2 0.6 0.26 11.6 0.0 4.4 4 1 1 5 5 3 1 AAA domain AAA_16 PF13191.6 EEB07798.1 - 0.00081 19.8 5.0 0.0011 19.4 0.1 3.5 4 1 0 4 4 2 1 AAA ATPase domain AAA_5 PF07728.14 EEB07798.1 - 0.00094 19.2 0.1 0.0057 16.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 EEB07798.1 - 0.0035 17.5 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 EEB07798.1 - 0.0039 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EEB07798.1 - 0.008 16.7 0.0 0.06 13.9 0.0 2.7 1 0 0 1 1 1 1 AAA domain Bromodomain PF00439.25 EEB07798.1 - 0.0084 16.2 0.1 0.028 14.5 0.1 1.9 1 0 0 1 1 1 1 Bromodomain ABC_tran PF00005.27 EEB07798.1 - 0.014 15.9 0.1 0.096 13.2 0.0 2.5 2 0 0 2 2 1 0 ABC transporter AAA_30 PF13604.6 EEB07798.1 - 0.018 14.7 0.1 0.048 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EEB07798.1 - 0.019 15.2 0.0 0.092 12.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EEB07798.1 - 0.054 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EEB07798.1 - 0.059 12.9 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEB07798.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 EEB07798.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EEB07798.1 - 0.077 12.7 0.0 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_14 PF13173.6 EEB07798.1 - 0.098 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EEB07798.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EEB07798.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EEB07798.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EEB07798.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EEB07798.1 - 0.43 10.3 0.0 0.43 10.3 0.0 3.3 3 2 0 3 3 1 0 AAA domain DUF3336 PF11815.8 EEB07799.1 - 6.5e-43 145.8 1.8 1.3e-42 144.8 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEB07799.1 - 2.4e-15 57.3 0.4 9.6e-15 55.3 0.4 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Requiem_N PF14051.6 EEB07799.1 - 0.23 11.7 1.4 0.72 10.1 1.4 1.8 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. DUF1744 PF08490.12 EEB07800.2 - 2e-122 408.7 0.1 3.2e-122 408.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EEB07800.2 - 4.1e-80 269.4 3.5 7.9e-80 268.5 3.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EEB07800.2 - 5.3e-14 51.8 1.8 3.5e-12 45.8 0.2 3.1 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EEB07800.2 - 5.6e-09 36.0 0.6 1.9e-08 34.2 0.6 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EEB07800.2 - 8.1e-05 22.7 0.0 0.0007 19.6 0.0 2.7 2 0 0 2 2 2 1 RNase_H superfamily Orn_Arg_deC_N PF02784.16 EEB07800.2 - 0.12 11.7 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain UNC-50 PF05216.13 EEB07801.1 - 1.2e-76 257.2 17.2 1.5e-76 256.9 17.2 1.0 1 0 0 1 1 1 1 UNC-50 family PDCD2_C PF04194.13 EEB07802.1 - 4.2e-31 108.3 6.2 1.5e-30 106.5 0.1 2.6 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zinc_ribbon_12 PF11331.8 EEB07802.1 - 0.29 11.0 3.0 0.89 9.4 0.2 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain Lipoprotein_10 PF03202.13 EEB07802.1 - 2.5 8.5 6.7 0.46 10.9 0.1 2.4 1 1 1 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region VHS PF00790.19 EEB07803.1 - 3.8e-44 150.0 0.0 1.1e-42 145.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EEB07803.1 - 2.8e-16 59.8 0.4 9.6e-16 58.1 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EEB07803.1 - 4.1e-06 26.3 0.6 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 EEB07803.1 - 2.5e-05 24.5 3.0 6.6e-05 23.1 0.6 2.8 2 0 0 2 2 2 1 GAT domain DUF2321 PF10083.9 EEB07803.1 - 0.0066 16.1 0.9 0.027 14.1 0.2 2.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) PIG-P PF08510.12 EEB07804.1 - 2.8e-35 120.9 7.0 5e-35 120.0 7.0 1.4 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.12 EEB07804.1 - 0.0083 16.4 8.4 0.014 15.7 8.4 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF1077 PF06417.12 EEB07805.1 - 5.5e-45 152.2 7.9 7.8e-45 151.7 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Tudor_3 PF18115.1 EEB07806.1 - 9.1e-13 47.8 0.0 1.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 EEB07806.1 - 6.2e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.6 EEB07806.1 - 0.00013 21.9 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EEB07806.1 - 0.0014 18.4 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Agenet PF05641.12 EEB07806.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Agenet domain Alpha-amylase PF00128.24 EEB07807.1 - 3.7e-23 82.6 11.2 2.8e-20 73.2 0.5 3.3 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EEB07807.1 - 3.2e-18 66.3 0.1 6e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EEB07807.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB07807.1 - 0.018 15.0 2.1 0.059 13.4 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Cid2 PF09774.9 EEB07808.1 - 3.4e-30 105.6 4.5 4e-30 105.4 4.5 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 UQ_con PF00179.26 EEB07809.1 - 9.2e-17 61.0 0.0 9.8e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEB07809.1 - 0.1 12.9 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain HSP20 PF00011.21 EEB07810.1 - 1.9e-20 72.9 0.1 2.2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EEB07810.1 - 2.4e-13 49.4 0.0 3.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EEB07810.1 - 0.0001 23.2 0.0 0.00016 22.6 0.0 1.2 1 0 0 1 1 1 1 CS domain NARP1 PF12569.8 EEB07811.1 - 2e-185 617.6 20.8 2e-185 617.6 20.8 1.8 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EEB07811.1 - 1.7e-08 34.0 29.3 0.24 11.6 0.1 10.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEB07811.1 - 4.3e-06 27.3 21.5 0.12 13.0 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEB07811.1 - 1.6e-05 25.0 0.1 9.5 6.9 0.0 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEB07811.1 - 2.6e-05 24.6 28.1 0.0033 17.9 0.2 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEB07811.1 - 3.6e-05 24.2 16.2 0.68 10.9 0.1 8.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB07811.1 - 0.00022 21.3 0.2 9.1 6.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEB07811.1 - 0.00036 20.2 0.8 0.008 15.8 0.2 3.3 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 EEB07811.1 - 0.00052 20.0 26.4 1.5 9.2 0.2 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB07811.1 - 0.0019 18.5 17.1 0.21 11.9 0.2 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB07811.1 - 0.048 13.7 9.2 27 5.1 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Erp_C PF06780.11 EEB07811.1 - 0.1 12.6 3.2 0.29 11.1 3.2 1.8 1 0 0 1 1 1 0 Erp protein C-terminus ANAPC3 PF12895.7 EEB07811.1 - 0.38 11.0 19.3 1.8 8.9 0.4 5.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EEB07811.1 - 1.4 8.9 25.0 1.2 9.0 0.5 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat SpoU_sub_bind PF08032.12 EEB07811.1 - 4.6 7.6 6.6 60 4.0 0.0 4.3 5 1 0 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding Fis1_TPR_C PF14853.6 EEB07811.1 - 7.4 6.7 14.9 1.3 9.2 0.0 5.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Gti1_Pac2 PF09729.9 EEB07812.1 - 1.4e-45 155.6 2.9 2.5e-44 151.5 2.9 2.0 1 1 0 1 1 1 1 Gti1/Pac2 family Myb_DNA-binding PF00249.31 EEB07813.2 - 3.3e-18 65.6 15.9 6.8e-13 48.6 2.2 4.7 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB07813.2 - 3.5e-17 62.4 13.8 2e-12 47.2 1.2 4.8 5 1 0 5 5 5 2 Myb-like DNA-binding domain APOBEC3 PF18771.1 EEB07813.2 - 0.0072 16.5 1.1 0.017 15.3 1.1 1.7 1 0 0 1 1 1 1 APOBEC3 SANT_DAMP1_like PF16282.5 EEB07813.2 - 0.13 12.5 8.2 0.88 9.8 0.6 3.8 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 Pkinase PF00069.25 EEB07814.1 - 7.3e-68 228.8 0.0 8.8e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07814.1 - 5e-32 111.2 0.0 7.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07814.1 - 3.4e-05 23.3 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB07814.1 - 0.0015 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB07814.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEB07814.1 - 0.0041 16.8 0.2 0.044 13.4 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEB07814.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family UvdE PF03851.14 EEB07814.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 UV-endonuclease UvdE Pkinase_fungal PF17667.1 EEB07814.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Phage_sheath_1C PF17482.2 EEB07814.1 - 0.16 12.0 0.0 0.57 10.2 0.0 1.9 2 1 0 2 2 2 0 Phage tail sheath C-terminal domain HEM4 PF02602.15 EEB07815.1 - 1.9e-31 109.2 0.0 2.2e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Fig1 PF12351.8 EEB07816.2 - 1.4e-07 31.6 9.1 1.4e-07 31.6 9.1 1.8 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EEB07816.2 - 0.00012 21.8 16.7 0.0002 21.0 16.7 1.3 1 1 0 1 1 1 1 SUR7/PalI family Cpn60_TCP1 PF00118.24 EEB07818.1 - 3.9e-156 520.5 2.7 4.4e-156 520.3 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bromodomain PF00439.25 EEB07819.1 - 6.8e-16 58.1 0.1 1.8e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EEB07819.1 - 1.4e-11 44.3 0.1 3.8e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain associated Lon_2 PF13337.6 EEB07819.1 - 0.028 13.0 0.0 0.073 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease UPF0179 PF03684.13 EEB07819.1 - 0.043 13.7 0.2 0.095 12.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) Zn_clus PF00172.18 EEB07823.2 - 7.1e-07 29.2 14.2 1.9e-06 27.9 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 EEB07824.1 - 7.6e-21 74.3 0.0 1.9e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 Transferase family AA_permease_2 PF13520.6 EEB07825.1 - 7.2e-50 170.1 52.7 9e-50 169.7 52.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07825.1 - 1.2e-12 47.2 43.4 1.7e-12 46.7 43.4 1.2 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.13 EEB07826.1 - 7.3e-28 97.6 4.9 1e-27 97.1 4.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Gp_dh_C PF02800.20 EEB07828.1 - 9.1e-72 239.8 0.1 1.3e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEB07828.1 - 4e-40 136.2 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEB07828.1 - 0.028 14.5 1.6 0.1 12.7 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EEB07828.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3576 PF12100.8 EEB07828.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) AA_permease PF00324.21 EEB07829.1 - 3.3e-113 378.8 43.3 4e-113 378.5 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB07829.1 - 2.1e-33 115.8 46.1 2.6e-33 115.5 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07830.2 - 4.6e-117 391.5 38.4 5.5e-117 391.3 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB07830.2 - 2.6e-29 102.3 40.3 3.4e-29 102.0 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease NRDD PF13597.6 EEB07831.1 - 6.9e-181 602.8 0.0 7.8e-181 602.7 0.0 1.0 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase DUF1610 PF07754.11 EEB07831.1 - 0.045 13.7 1.5 0.12 12.4 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Melibiase_2 PF16499.5 EEB07832.1 - 6.9e-62 209.2 10.3 3e-61 207.1 10.3 1.9 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EEB07832.1 - 1e-12 47.9 1.3 1.7e-12 47.2 0.5 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EEB07832.1 - 5.3e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Melibiase GalKase_gal_bdg PF10509.9 EEB07833.2 - 5.2e-20 70.7 0.0 1.2e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EEB07833.2 - 3.2e-16 59.3 0.4 3.2e-16 59.3 0.4 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEB07833.2 - 2.2e-13 50.4 0.0 4.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.20 EEB07834.1 - 7e-65 219.3 0.2 1.1e-64 218.7 0.2 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.21 EEB07834.1 - 3.1e-51 174.1 0.0 5.4e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEB07834.1 - 7.3e-48 163.7 0.0 1.1e-47 163.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EEB07834.1 - 4.9e-17 61.8 0.2 9.1e-17 61.0 0.2 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EEB07834.1 - 4.3e-16 58.9 0.0 1e-14 54.4 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EEB07834.1 - 8.4e-13 48.1 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EEB07834.1 - 3.8e-07 30.2 0.0 7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EEB07834.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EEB07834.1 - 1.3e-06 27.8 0.1 6.4e-05 22.2 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EEB07834.1 - 1.4e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 EEB07834.1 - 0.026 14.1 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EEB07834.1 - 0.098 12.2 0.5 0.27 10.7 0.5 1.9 1 1 0 1 1 1 0 NmrA-like family RRM_1 PF00076.22 EEB07835.1 - 7.3e-14 51.3 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TbpB_A PF17484.2 EEB07835.1 - 0.04 14.7 0.5 0.04 14.7 0.5 1.7 2 0 0 2 2 2 0 N-Lobe handle Tf-binding protein B Nup35_RRM_2 PF14605.6 EEB07835.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GalP_UDP_transf PF01087.22 EEB07836.1 - 2.6e-65 220.3 0.1 3.7e-65 219.8 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EEB07836.1 - 8.8e-65 217.5 0.2 1.7e-64 216.5 0.2 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 EEB07836.1 - 0.0034 17.9 0.1 0.0065 16.9 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EEB07836.1 - 0.032 15.0 0.0 0.089 13.5 0.0 1.8 2 0 0 2 2 2 0 HIT domain DUF4921 PF16268.5 EEB07836.1 - 0.14 10.9 0.0 6 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) AA_permease PF00324.21 EEB07837.1 - 2.7e-114 382.4 43.7 3.2e-114 382.1 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB07837.1 - 7.8e-25 87.6 46.6 1.8e-24 86.4 46.3 1.6 1 1 1 2 2 2 1 Amino acid permease Zn_clus PF00172.18 EEB07838.2 - 7.5e-07 29.2 10.3 1.5e-06 28.2 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2959 PF11172.8 EEB07838.2 - 0.069 13.3 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) RTA1 PF04479.13 EEB07839.1 - 4e-55 186.6 9.2 5.9e-55 186.1 9.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2678 PF10856.8 EEB07839.1 - 1.8 8.5 7.2 1.2 9.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Sugar_tr PF00083.24 EEB07840.2 - 5.6e-107 358.4 21.3 6.7e-107 358.1 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB07840.2 - 1.2e-15 57.3 32.7 1.4e-12 47.2 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 EEB07840.2 - 1.5 8.6 3.5 1.9 8.3 0.3 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Metallophos PF00149.28 EEB07841.1 - 3.2e-14 53.9 6.1 3.2e-14 53.9 6.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EEB07841.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Epimerase PF01370.21 EEB07842.1 - 5.5e-16 58.8 0.0 8.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEB07842.1 - 5.7e-10 38.7 0.0 9e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EEB07842.1 - 1.1e-09 38.5 0.0 6.2e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EEB07842.1 - 1.1e-09 38.2 0.0 3.5e-09 36.5 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEB07842.1 - 1.1e-09 37.8 0.0 3.5e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EEB07842.1 - 2.7e-05 23.4 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EEB07842.1 - 0.0073 15.9 0.2 0.028 14.0 0.0 2.0 2 1 0 2 2 2 1 NmrA-like family DUF4213 PF13938.6 EEB07842.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation adh_short PF00106.25 EEB07842.1 - 0.089 12.2 0.0 2.9 7.3 0.0 2.7 3 0 0 3 3 3 0 short chain dehydrogenase Epimerase PF01370.21 EEB07843.1 - 5.8e-12 45.6 0.0 1.2e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEB07843.1 - 4.4e-06 26.7 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEB07843.1 - 0.001 18.7 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EEB07843.1 - 0.013 14.5 0.1 0.22 10.5 0.1 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEB07843.1 - 0.042 13.3 0.0 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEB07843.1 - 0.051 12.7 0.1 0.82 8.8 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein VAR1 PF05316.12 EEB07843.1 - 0.079 12.0 0.1 0.15 11.1 0.1 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein (VAR1) ThiF PF00899.21 EEB07843.1 - 0.13 11.6 0.2 0.36 10.2 0.2 1.5 1 1 1 2 2 2 0 ThiF family MFS_1 PF07690.16 EEB07844.1 - 1.5e-27 96.5 39.3 6.3e-26 91.1 14.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07844.1 - 5.9e-07 28.7 10.8 5.9e-07 28.7 10.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter ADH_N PF08240.12 EEB07845.1 - 1.2e-30 105.6 2.1 1.9e-30 104.9 2.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB07845.1 - 1.8e-17 63.5 0.0 3.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB07845.1 - 9.9e-09 36.3 0.0 1.6e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEB07845.1 - 7.4e-07 28.7 0.1 1.7e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEB07845.1 - 1.7e-05 24.3 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EEB07845.1 - 0.095 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EEB07845.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EEB07845.1 - 0.17 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Iron_permease PF04120.12 EEB07848.1 - 1.3e-45 154.3 10.9 3.9e-15 55.8 0.2 4.2 4 0 0 4 4 4 4 Low affinity iron permease PEN-2 PF10251.9 EEB07848.1 - 5.4 7.5 9.9 2.5 8.6 0.2 2.9 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Cys_Met_Meta_PP PF01053.20 EEB07850.1 - 2.2e-154 513.6 0.0 2.5e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEB07850.1 - 8.1e-13 48.3 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EEB07850.1 - 2.6e-11 43.4 0.1 4.5e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EEB07850.1 - 4.6e-08 32.4 0.2 7.9e-08 31.6 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EEB07850.1 - 0.00015 20.4 0.3 0.00034 19.3 0.3 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EEB07850.1 - 0.0027 17.1 0.0 0.0085 15.4 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase TNV_CP PF03898.13 EEB07850.1 - 0.019 14.3 0.2 0.037 13.3 0.2 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein SepSecS PF05889.13 EEB07850.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pyridoxal_deC PF00282.19 EEB07850.1 - 0.061 12.0 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Asparaginase_C PF17763.1 EEB07850.1 - 0.091 13.0 0.0 0.47 10.7 0.0 2.1 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain Flagellin_IN PF07196.13 EEB07850.1 - 0.098 12.9 0.7 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 Flagellin hook IN motif GDC-P PF02347.16 EEB07850.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Methyltransf_25 PF13649.6 EEB07851.1 - 3.7e-19 69.2 0.0 6.6e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB07851.1 - 8e-19 68.1 0.0 4.6e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB07851.1 - 4.2e-10 39.7 0.0 5.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB07851.1 - 5.6e-10 39.2 0.0 8.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB07851.1 - 2.9e-09 37.6 0.0 4.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEB07851.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EEB07851.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 EEB07851.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EEB07851.1 - 0.0059 16.2 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EEB07851.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DIL PF01843.19 EEB07852.1 - 8e-24 83.9 0.2 1.4e-23 83.1 0.2 1.4 1 0 0 1 1 1 1 DIL domain HIG_1_N PF04588.13 EEB07853.1 - 5.4e-20 71.3 2.1 8.4e-20 70.7 2.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region BORCS8 PF10167.9 EEB07854.1 - 0.0058 16.6 0.7 0.0063 16.4 0.7 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 MtrG PF04210.13 EEB07854.1 - 0.023 14.6 0.1 0.035 14.0 0.1 1.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G tRNA-synt_2b PF00587.25 EEB07855.1 - 1.1e-15 58.0 0.0 2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEB07855.1 - 1.9e-12 47.4 3.6 3.4e-12 46.5 3.6 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.6 EEB07855.1 - 0.044 14.1 2.0 0.11 12.9 2.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PseudoU_synth_1 PF01416.20 EEB07856.1 - 8.8e-37 125.9 0.0 5.4e-31 107.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase zf-Mss51 PF13824.6 EEB07857.1 - 1.1e-18 67.0 1.2 2.3e-18 66.0 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 PS_Dcarbxylase PF02666.15 EEB07858.1 - 7.1e-68 228.1 0.0 1.9e-67 226.7 0.0 1.7 2 1 0 2 2 2 1 Phosphatidylserine decarboxylase M-inducer_phosp PF06617.13 EEB07858.1 - 0.03 13.6 0.2 0.045 13.0 0.2 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase Sds3 PF08598.11 EEB07859.1 - 1.5e-21 77.4 7.5 2e-21 77.0 7.5 1.1 1 0 0 1 1 1 1 Sds3-like Cyt-b5 PF00173.28 EEB07860.2 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TNFR_16_TM PF18422.1 EEB07860.2 - 0.0014 18.5 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain VEFS-Box PF09733.9 EEB07860.2 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein His_Phos_1 PF00300.22 EEB07862.1 - 1.6e-21 76.9 0.0 2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AcetylCoA_hyd_C PF13336.6 EEB07863.1 - 1.6e-41 141.8 0.0 2.3e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EEB07863.1 - 5.1e-25 88.6 0.0 1e-24 87.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AA_permease_2 PF13520.6 EEB07864.1 - 2.9e-40 138.4 45.3 3.5e-40 138.1 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB07864.1 - 1.7e-17 63.2 41.0 2.4e-17 62.7 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease DJ-1_PfpI PF01965.24 EEB07866.1 - 2.9e-11 43.4 0.0 1.6e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EEB07866.1 - 3.8e-06 26.7 0.2 0.00016 21.4 0.2 2.4 1 1 0 1 1 1 1 ThiJ/PfpI family-like PH PF00169.29 EEB07867.1 - 0.0036 17.8 0.0 0.0091 16.5 0.0 1.7 1 0 0 1 1 1 1 PH domain MOZ_SAS PF01853.18 EEB07868.1 - 6.4e-84 280.1 1.0 9e-84 279.6 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEB07868.1 - 2.9e-24 84.4 4.1 2.9e-24 84.4 4.1 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EEB07868.1 - 7.1e-19 67.5 1.2 1.4e-18 66.6 1.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EEB07868.1 - 0.00096 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB07868.1 - 0.0062 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_16 PF05301.11 EEB07868.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 IF2_N PF04760.15 EEB07868.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Helicase_C PF00271.31 EEB07869.1 - 1.5e-09 38.2 0.0 4.7e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EEB07869.1 - 3e-08 33.4 1.5 4.7e-08 32.8 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal VWA_2 PF13519.6 EEB07870.2 - 1.4e-23 83.6 0.1 6.3e-23 81.5 0.0 2.0 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 EEB07870.2 - 6e-10 39.6 0.2 9.8e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EEB07870.2 - 2.5e-09 37.2 0.1 4.1e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like CdiA_C_tRNase PF18664.1 EEB07870.2 - 0.018 15.2 0.5 0.033 14.4 0.5 1.5 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain UIM PF02809.20 EEB07870.2 - 0.039 13.9 1.1 0.098 12.6 1.1 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif RNase_T PF00929.24 EEB07871.1 - 1.2e-07 32.4 0.0 2.7e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Exonuclease FGF-BP1 PF06473.12 EEB07871.1 - 6.6 6.5 11.8 3.7 7.3 0.1 2.3 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) ParA PF10609.9 EEB07872.1 - 4.1e-100 334.3 0.0 4.8e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEB07872.1 - 2.4e-11 43.8 0.0 7e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EEB07872.1 - 6.3e-08 32.7 0.1 5e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EEB07872.1 - 2.8e-07 30.0 0.5 6.6e-06 25.5 0.1 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EEB07872.1 - 0.00042 19.7 0.0 0.00069 19.0 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EEB07872.1 - 0.0015 18.4 0.0 0.067 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEB07872.1 - 0.0051 16.7 0.3 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase CBP_BcsQ PF06564.12 EEB07872.1 - 0.017 14.6 0.1 0.058 12.9 0.1 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EEB07872.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EEB07872.1 - 0.03 13.8 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EEB07872.1 - 0.034 13.8 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EEB07872.1 - 0.054 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zn_Tnp_IS1595 PF12760.7 EEB07872.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rad17 PF03215.15 EEB07872.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PcrB PF01884.17 EEB07872.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 PcrB family TsaE PF02367.17 EEB07872.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EEB07872.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EEB07872.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.4 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EEB07872.1 - 0.21 11.7 0.0 0.59 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 EEB07873.1 - 9.1e-207 688.1 0.0 1e-206 688.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_34 PF05637.12 EEB07874.1 - 6.7e-70 235.5 0.1 7.9e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family AAA PF00004.29 EEB07875.1 - 6.8e-49 165.7 0.0 2.1e-44 151.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB07875.1 - 1.3e-08 34.5 0.0 2.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EEB07875.1 - 1.8e-06 28.4 3.3 0.002 18.5 0.1 4.6 4 1 1 5 5 5 1 AAA ATPase domain RuvB_N PF05496.12 EEB07875.1 - 5.7e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB07875.1 - 0.00013 22.3 0.2 0.0013 19.0 0.0 2.8 3 1 1 4 4 3 1 AAA domain AAA_2 PF07724.14 EEB07875.1 - 0.00024 21.3 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EEB07875.1 - 0.00026 20.3 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EEB07875.1 - 0.0012 18.1 0.0 0.0037 16.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EEB07875.1 - 0.0021 18.1 0.0 0.0082 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EEB07875.1 - 0.0029 17.3 0.1 0.014 15.1 0.0 2.1 3 0 0 3 3 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EEB07875.1 - 0.0048 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EEB07875.1 - 0.0072 16.9 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EEB07875.1 - 0.0081 15.6 0.2 0.02 14.3 0.1 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EEB07875.1 - 0.0088 15.6 0.7 0.18 11.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain Vps4_C PF09336.10 EEB07875.1 - 0.015 15.3 0.0 0.046 13.7 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 EEB07875.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EEB07875.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 EEB07875.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EEB07875.1 - 0.022 13.9 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EEB07875.1 - 0.022 14.5 0.5 0.13 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EEB07875.1 - 0.028 14.4 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB07875.1 - 0.032 14.2 0.2 0.63 9.9 0.0 2.8 2 1 0 3 3 3 0 NACHT domain TsaE PF02367.17 EEB07875.1 - 0.034 14.1 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EEB07875.1 - 0.04 13.8 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EEB07875.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Importin_rep_4 PF18808.1 EEB07876.1 - 3.4e-29 101.0 0.6 3.4e-29 101.0 0.6 3.5 4 0 0 4 4 3 1 Importin repeat HEAT_EZ PF13513.6 EEB07876.1 - 3.3e-25 88.1 17.7 4.8e-10 39.7 0.2 9.1 6 2 2 8 8 7 6 HEAT-like repeat HEAT_2 PF13646.6 EEB07876.1 - 2e-17 63.3 15.5 3.8e-06 27.2 0.0 8.4 4 2 4 9 9 9 5 HEAT repeats HEAT PF02985.22 EEB07876.1 - 7.2e-17 60.0 20.7 5.7e-05 23.0 0.0 12.1 13 0 0 13 13 12 2 HEAT repeat Importin_rep_5 PF18816.1 EEB07876.1 - 1.5e-13 50.8 0.2 5.6e-13 49.0 0.2 2.0 1 0 0 1 1 1 1 Importin repeat RIX1 PF08167.12 EEB07876.1 - 5.6e-12 45.8 0.0 0.00052 19.8 0.0 5.2 4 1 1 5 5 5 4 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 EEB07876.1 - 3e-11 43.4 2.0 1.2e-10 41.4 0.5 2.8 2 1 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EEB07876.1 - 2.3e-10 40.9 1.4 0.00049 20.6 0.0 6.2 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EEB07876.1 - 5.3e-09 36.2 1.3 0.012 15.5 0.1 6.4 7 1 1 8 8 8 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EEB07876.1 - 4.5e-08 33.3 0.5 0.007 16.4 0.0 5.7 6 2 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EEB07876.1 - 1.6e-07 30.3 0.2 0.0021 16.7 0.0 4.0 3 1 0 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 EEB07876.1 - 8.5e-07 29.1 1.6 0.24 11.6 0.1 5.1 5 0 0 5 5 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EEB07876.1 - 1.4e-06 28.0 0.1 0.031 13.8 0.1 6.1 5 2 0 6 6 6 1 CLASP N terminal Arm PF00514.23 EEB07876.1 - 0.00011 22.1 6.6 0.24 11.5 0.1 6.8 8 0 0 8 8 6 1 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 EEB07876.1 - 0.0067 16.3 0.0 0.29 11.0 0.0 3.5 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal IBN_N PF03810.19 EEB07876.1 - 0.0068 16.3 0.1 4.7 7.2 0.0 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain IFRD PF05004.13 EEB07876.1 - 0.034 13.3 4.4 3.4 6.7 0.1 5.0 3 2 2 5 5 5 0 Interferon-related developmental regulator (IFRD) V-ATPase_H_N PF03224.14 EEB07876.1 - 0.053 12.8 0.4 1.5 8.0 0.0 2.6 2 1 0 2 2 2 0 V-ATPase subunit H DUF4473 PF14747.6 EEB07876.1 - 0.13 12.8 0.1 41 4.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF4042 PF13251.6 EEB07876.1 - 0.24 11.1 5.8 12 5.5 0.0 4.6 6 0 0 6 6 5 0 Domain of unknown function (DUF4042) MMS19_C PF12460.8 EEB07876.1 - 0.29 10.2 4.9 0.58 9.2 0.1 3.6 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal Glucan_synthase PF02364.15 EEB07877.2 - 0 1333.4 0.0 0 1332.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEB07877.2 - 4.4e-36 124.1 0.4 1.3e-35 122.5 0.4 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1390 PF07150.11 EEB07877.2 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Mog1 PF04603.12 EEB07878.2 - 2.2e-34 118.8 0.0 2.7e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rhomboid PF01694.22 EEB07879.2 - 6.3e-22 78.2 8.0 8.8e-22 77.7 8.0 1.2 1 0 0 1 1 1 1 Rhomboid family Pep3_Vps18 PF05131.14 EEB07880.1 - 1.1e-29 103.1 1.1 9.8e-27 93.6 0.1 3.4 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 EEB07880.1 - 8.9e-08 32.6 1.6 2.6e-07 31.0 1.6 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EEB07880.1 - 9.5e-05 22.3 10.6 0.00019 21.3 1.3 3.7 3 1 1 4 4 4 1 Region in Clathrin and VPS Sec16_C PF12931.7 EEB07880.1 - 0.036 13.7 0.1 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 P16-Arc PF04699.14 EEB07880.1 - 0.04 14.4 1.9 0.097 13.2 0.3 2.5 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) zf-RING_11 PF17123.5 EEB07880.1 - 0.13 12.1 4.2 0.43 10.4 4.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EEB07880.1 - 0.32 11.0 5.9 0.68 9.9 5.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEB07880.1 - 0.47 10.5 4.2 1.4 9.0 4.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EEB07880.1 - 0.47 10.8 2.7 1.2 9.4 2.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EEB07880.1 - 0.51 10.4 5.9 1.4 9.1 5.9 1.7 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.25 EEB07880.1 - 2.2 8.2 6.2 5.7 6.9 6.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB07880.1 - 3.8 7.9 7.0 9.4 6.7 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EEB07880.1 - 8.8 6.3 10.9 0.23 11.3 4.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRE1 PF08647.11 EEB07881.1 - 3.7e-18 65.4 5.5 3.7e-18 65.4 5.5 5.4 5 2 0 5 5 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EEB07881.1 - 4e-05 23.4 11.7 6.8e-05 22.7 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEB07881.1 - 0.00068 19.5 12.1 0.00096 19.0 11.4 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEB07881.1 - 0.00088 19.1 14.9 0.0019 18.0 14.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB07881.1 - 0.0022 18.3 13.8 0.0044 17.3 13.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB07881.1 - 0.0024 17.7 12.9 0.0049 16.7 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB07881.1 - 0.0026 17.7 8.4 0.0064 16.5 8.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EEB07881.1 - 0.0033 17.2 6.8 0.0079 16.0 6.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain ADIP PF11559.8 EEB07881.1 - 0.0052 16.9 2.4 0.0052 16.9 2.4 6.2 3 1 4 7 7 6 1 Afadin- and alpha -actinin-Binding zf-RING_5 PF14634.6 EEB07881.1 - 0.032 14.2 12.9 0.068 13.1 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 EEB07881.1 - 0.032 14.1 4.2 0.067 13.1 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EEB07881.1 - 0.034 14.4 10.8 0.083 13.2 10.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEB07881.1 - 0.035 14.3 9.7 0.11 12.6 9.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FliG_N PF14842.6 EEB07881.1 - 0.041 14.4 0.2 0.041 14.4 0.2 4.3 2 1 2 4 4 4 0 FliG N-terminal domain DUF2854 PF11016.8 EEB07881.1 - 0.24 11.3 4.5 0.28 11.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) Myb_DNA-bind_7 PF15963.5 EEB07882.2 - 3.2e-29 100.7 0.1 3.2e-29 100.7 0.1 2.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EEB07882.2 - 1.4e-06 28.3 0.0 3.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2431 PF10354.9 EEB07883.1 - 2.4e-56 190.6 0.1 3.3e-56 190.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) LPD22 PF18834.1 EEB07883.1 - 0.0059 16.8 0.0 0.028 14.6 0.0 2.0 3 0 0 3 3 3 1 Large polyvalent protein associated domain 22 Methyltr_RsmB-F PF01189.17 EEB07883.1 - 0.018 14.7 0.1 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F UPF0020 PF01170.18 EEB07883.1 - 0.054 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Peptidase_M28 PF04389.17 EEB07884.1 - 2.6e-38 131.7 0.1 4.1e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEB07884.1 - 0.00071 19.3 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEB07884.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase BAR PF03114.18 EEB07885.2 - 4.4e-34 118.2 9.8 7.4e-34 117.4 9.8 1.4 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EEB07885.2 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEB07885.2 - 2e-06 27.3 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.9 EEB07885.2 - 3.1e-05 23.3 6.3 3.1e-05 23.3 6.3 2.0 1 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.17 EEB07885.2 - 7.3e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1415 PF07209.12 EEB07885.2 - 0.094 12.5 0.9 0.2 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Prefoldin_3 PF13758.6 EEB07885.2 - 0.47 10.5 4.9 0.51 10.4 2.1 2.5 3 0 0 3 3 3 0 Prefoldin subunit Myosin_head PF00063.21 EEB07886.2 - 1.3e-258 859.8 11.9 2.4e-258 858.9 11.9 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EEB07886.2 - 5.4e-16 58.8 1.8 5.4e-16 58.8 1.8 2.9 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 EEB07886.2 - 3.3e-12 45.1 20.6 0.0072 16.0 0.2 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.19 EEB07886.2 - 0.00036 20.3 1.3 0.00087 19.1 1.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EEB07886.2 - 0.0085 16.4 0.0 0.11 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EEB07886.2 - 0.046 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EEB07886.2 - 0.051 14.0 0.1 0.52 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain FlaC_arch PF05377.11 EEB07886.2 - 1.4 9.4 8.2 58 4.2 0.5 4.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) eIF-6 PF01912.18 EEB07887.1 - 3.3e-80 268.1 0.3 4.1e-80 267.8 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family Ureidogly_lyase PF04115.12 EEB07888.1 - 2e-46 158.1 0.0 2.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Polysacc_deac_1 PF01522.21 EEB07889.1 - 2.8e-17 62.8 0.0 4.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase RNA_pol PF00940.19 EEB07890.1 - 1.9e-172 573.8 0.0 2.5e-172 573.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EEB07890.1 - 5.1e-87 292.4 0.0 1.5e-86 290.9 0.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Kei1 PF08552.11 EEB07891.2 - 3.4e-41 141.2 11.2 6.1e-41 140.4 11.2 1.4 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 PsbI PF02532.14 EEB07891.2 - 0.048 13.6 2.2 0.15 12.0 2.2 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Bmt2 PF11968.8 EEB07892.1 - 8.5e-66 222.0 0.0 1.1e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Involucrin_N PF10583.9 EEB07892.1 - 0.056 14.0 0.3 0.19 12.4 0.1 1.9 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus PRK PF00485.18 EEB07893.1 - 3.2e-06 27.0 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EEB07893.1 - 0.00011 22.7 0.1 0.00034 21.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEB07893.1 - 0.00048 20.5 0.0 0.00087 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 EEB07893.1 - 0.0011 17.9 0.1 0.0047 15.9 0.0 1.9 2 1 1 3 3 3 1 PrkA AAA domain AAA_22 PF13401.6 EEB07893.1 - 0.0021 18.4 0.1 0.0051 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEB07893.1 - 0.0042 17.6 0.2 0.026 15.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter G-alpha PF00503.20 EEB07893.1 - 0.0045 16.2 0.3 0.46 9.6 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit KAP_NTPase PF07693.14 EEB07893.1 - 0.0056 16.0 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_28 PF13521.6 EEB07893.1 - 0.0075 16.5 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB07893.1 - 0.0079 16.6 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 EEB07893.1 - 0.0086 16.1 0.1 0.025 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EEB07893.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EEB07893.1 - 0.012 16.1 0.0 0.04 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EEB07893.1 - 0.013 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 EEB07893.1 - 0.015 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EEB07893.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EEB07893.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EEB07893.1 - 0.034 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EEB07893.1 - 0.05 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 EEB07893.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase NB-ARC PF00931.22 EEB07893.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EEB07893.1 - 0.083 12.7 0.2 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EEB07893.1 - 0.086 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EEB07893.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EEB07893.1 - 0.094 12.2 0.2 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 EEB07893.1 - 0.11 12.6 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EEB07893.1 - 0.16 11.9 0.0 0.69 9.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FA_hydroxylase PF04116.13 EEB07894.1 - 4.5e-26 91.8 21.1 4.5e-26 91.8 21.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2011 PF09428.10 EEB07896.1 - 1.9e-08 34.4 0.8 3.7e-08 33.5 0.7 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) RabGAP-TBC PF00566.18 EEB07897.1 - 1.4e-24 86.9 16.6 1.3e-18 67.4 9.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 EEB07897.1 - 1.1e-07 31.5 0.0 1.8e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Rab-binding domain (RBD) Peptidase_M18 PF02127.15 EEB07898.1 - 1.3e-181 604.1 0.0 1.5e-181 603.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EEB07898.1 - 9.8e-05 21.5 0.0 0.0029 16.7 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Ge1_WD40 PF16529.5 EEB07899.1 - 5.7e-07 28.8 0.1 0.0032 16.5 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1899 PF08953.11 EEB07899.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Adaptin_binding PF10199.9 EEB07899.1 - 4.8 7.8 18.4 1.6 9.3 0.4 3.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF3584 PF12128.8 EEB07899.1 - 8.6 3.7 33.8 16 2.9 33.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERG4_ERG24 PF01222.17 EEB07900.1 - 2.9e-175 583.2 21.6 3.3e-175 583.0 21.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Cofilin_ADF PF00241.20 EEB07901.1 - 1.4e-42 144.3 0.3 1.6e-42 144.1 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Hus1 PF04005.12 EEB07902.2 - 1.1e-83 280.8 0.8 1.3e-83 280.5 0.8 1.0 1 0 0 1 1 1 1 Hus1-like protein WD40 PF00400.32 EEB07903.1 - 7.7e-19 67.7 7.2 0.00028 21.6 0.3 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07903.1 - 0.00032 20.9 0.1 0.11 12.8 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB07903.1 - 0.012 14.3 0.0 2.9 6.4 0.0 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DUF1754 PF08555.10 EEB07903.1 - 0.5 11.2 6.8 1.1 10.1 6.8 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Prenyltrans PF00432.21 EEB07904.1 - 1.6e-32 110.9 6.5 3.8e-13 48.9 0.1 5.0 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EEB07904.1 - 0.11 11.5 0.0 3 6.9 0.0 2.1 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain DnaJ PF00226.31 EEB07905.1 - 1.5e-15 57.0 0.9 3.2e-15 56.0 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Pox_polyA_pol_N PF12630.7 EEB07905.1 - 0.075 13.4 0.9 3.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain TMEMspv1-c74-12 PF11044.8 EEB07905.1 - 0.11 12.5 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PRA1 PF03208.19 EEB07906.1 - 2e-06 27.5 13.7 2.5e-06 27.2 13.7 1.1 1 0 0 1 1 1 1 PRA1 family protein Glyco_hydro_47 PF01532.20 EEB07907.2 - 1e-161 538.9 0.1 1.2e-161 538.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_S6e PF01092.19 EEB07909.1 - 5.8e-59 197.5 0.6 1.9e-58 195.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e CFAP91 PF14738.6 EEB07909.1 - 0.016 15.3 5.7 0.022 14.8 5.7 1.2 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 RNA_pol_Rpb4 PF03874.16 EEB07910.1 - 5.7e-21 75.1 4.4 6.8e-21 74.9 4.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 NPA PF16469.5 EEB07910.1 - 0.066 13.8 1.0 1.5 9.4 1.1 2.1 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 CbiG_C PF01890.16 EEB07910.1 - 0.068 13.7 0.1 0.12 13.0 0.1 1.4 1 1 0 1 1 1 0 Cobalamin synthesis G C-terminus TIP49 PF06068.13 EEB07911.2 - 2.3e-158 527.0 3.1 3e-158 526.6 3.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEB07911.2 - 4.1e-24 84.5 2.4 1.4e-23 82.8 2.2 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EEB07911.2 - 5e-11 43.1 2.7 4.2e-07 30.5 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEB07911.2 - 8e-08 32.2 0.5 0.0013 18.5 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEB07911.2 - 2.7e-05 24.6 0.1 0.00018 22.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EEB07911.2 - 0.00016 21.1 0.8 0.0094 15.4 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 EEB07911.2 - 0.00027 20.4 0.2 0.00069 19.0 0.2 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EEB07911.2 - 0.0011 19.2 0.1 0.33 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEB07911.2 - 0.0033 17.4 0.2 2.4 8.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EEB07911.2 - 0.0037 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EEB07911.2 - 0.0066 16.2 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 EEB07911.2 - 0.015 15.6 2.8 0.069 13.5 0.8 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEB07911.2 - 0.016 15.4 0.3 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEB07911.2 - 0.054 13.0 0.1 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region CPT PF07931.12 EEB07911.2 - 0.054 13.3 0.5 0.76 9.6 0.5 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 EEB07911.2 - 0.083 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 EEB07911.2 - 0.1 12.1 0.3 0.28 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Apc15p PF05841.11 EEB07912.1 - 3e-07 31.3 0.1 7.3e-07 30.0 0.0 1.6 1 1 1 2 2 2 1 Apc15p protein DNA_pol_phi PF04931.13 EEB07912.1 - 0.15 10.1 8.2 0.16 10.0 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EEB07912.1 - 2.5 7.1 12.5 3.4 6.7 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA12 PF10443.9 EEB07913.1 - 2.3e-120 402.3 0.0 2.7e-74 250.5 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 EEB07913.1 - 1.5e-06 28.3 0.2 9.8e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EEB07913.1 - 0.0002 21.8 0.1 0.00083 19.8 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain RRM_1 PF00076.22 EEB07913.1 - 0.00028 20.6 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMC2NT PF08066.12 EEB07913.1 - 0.055 14.2 0.3 0.27 11.9 0.1 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain MFS_1 PF07690.16 EEB07914.1 - 1.5e-19 70.1 32.9 1.4e-18 67.0 34.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L36 PF00444.18 EEB07915.1 - 8.8e-15 54.6 4.3 1.6e-14 53.8 4.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 NPH-II PF12011.8 EEB07915.1 - 0.0045 16.9 0.1 0.008 16.1 0.1 1.3 1 0 0 1 1 1 1 RNA helicase NPH-II TFIIA PF03153.13 EEB07915.1 - 0.12 12.4 16.5 0.13 12.2 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit JmjC PF02373.22 EEB07916.2 - 3.1e-26 92.0 0.1 5.1e-25 88.1 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EEB07916.2 - 1.6e-05 24.8 0.2 3e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 jmjN domain Ago_hook PF10427.9 EEB07917.2 - 1.6e-34 119.8 26.0 2.4e-34 119.2 26.0 1.3 1 0 0 1 1 1 1 Argonaute hook Ribosomal_L37ae PF01780.19 EEB07918.1 - 5.6e-37 125.7 8.0 6.3e-37 125.5 8.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DNA_ligase_ZBD PF03119.16 EEB07918.1 - 0.0013 18.7 0.7 0.002 18.1 0.7 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain Lar_restr_allev PF14354.6 EEB07918.1 - 0.018 15.4 0.2 0.027 14.9 0.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_13 PF17977.1 EEB07918.1 - 0.059 13.5 1.4 0.08 13.1 1.4 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EEB07918.1 - 0.07 13.1 3.7 0.12 12.4 3.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 EEB07918.1 - 0.074 12.8 3.8 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 EEB07918.1 - 0.1 13.1 1.1 0.18 12.3 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 EEB07918.1 - 1.9 9.1 3.9 2.1 8.9 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type EF-hand_4 PF12763.7 EEB07919.1 - 2.3e-26 91.8 0.1 3.2e-10 39.9 0.1 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EEB07919.1 - 1.8e-11 43.7 0.2 3.8e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 EEB07919.1 - 4.7e-10 39.8 0.4 0.017 15.5 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EEB07919.1 - 3.3e-08 32.5 0.2 0.04 13.5 0.0 4.4 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 EEB07919.1 - 9.9e-08 31.3 0.2 0.14 12.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EEB07919.1 - 0.00019 21.2 1.3 1.2 9.1 0.0 4.1 3 1 1 4 4 4 1 EF-hand domain pair HAP1_N PF04849.13 EEB07919.1 - 0.00053 19.3 7.1 0.00053 19.3 7.1 1.6 2 0 0 2 2 1 1 HAP1 N-terminal conserved region HOOK PF05622.12 EEB07919.1 - 0.0012 17.1 8.5 0.0017 16.6 8.5 1.1 1 0 0 1 1 1 1 HOOK protein Laminin_I PF06008.14 EEB07919.1 - 0.0019 18.0 5.4 0.0039 16.9 5.4 1.5 1 0 0 1 1 1 1 Laminin Domain I HIP1_clath_bdg PF16515.5 EEB07919.1 - 0.0037 17.8 9.2 0.011 16.3 9.2 1.8 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CUE PF02845.16 EEB07919.1 - 0.0043 16.7 0.3 0.011 15.4 0.3 1.7 1 0 0 1 1 1 1 CUE domain PI3K_P85_iSH2 PF16454.5 EEB07919.1 - 0.0049 16.5 9.8 0.0099 15.5 9.8 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GAS PF13851.6 EEB07919.1 - 0.014 14.8 10.6 0.029 13.7 10.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 EEB07919.1 - 0.034 14.4 7.4 1.6 9.0 0.9 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATG16 PF08614.11 EEB07919.1 - 0.051 13.8 13.1 0.23 11.7 13.1 2.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1542 PF07564.11 EEB07919.1 - 0.055 13.6 1.2 0.23 11.6 1.2 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) TMF_DNA_bd PF12329.8 EEB07919.1 - 0.072 13.1 7.4 0.17 11.9 7.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 EEB07919.1 - 0.089 11.4 2.7 0.14 10.7 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1824 PF08854.10 EEB07919.1 - 0.26 11.2 3.9 5.8 6.9 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1824) DUF4201 PF13870.6 EEB07919.1 - 0.27 11.0 11.9 0.58 9.9 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SKA2 PF16740.5 EEB07919.1 - 0.28 11.0 6.7 0.69 9.7 6.7 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 EEB07919.1 - 0.59 10.6 12.2 7.7 7.0 12.3 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF812 PF05667.11 EEB07919.1 - 0.65 8.8 14.2 1 8.1 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 EEB07919.1 - 0.77 10.0 9.8 0.54 10.5 6.9 2.3 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EEB07919.1 - 0.93 8.8 9.1 1.9 7.8 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EEB07919.1 - 1 9.5 12.7 2 8.5 12.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EEB07919.1 - 1.1 8.0 10.4 2.3 7.0 10.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein GvpL_GvpF PF06386.11 EEB07919.1 - 1.1 9.1 10.0 2.9 7.8 10.0 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Fez1 PF06818.15 EEB07919.1 - 1.2 9.6 12.7 0.53 10.7 10.1 1.8 2 0 0 2 2 1 0 Fez1 TMF_TATA_bd PF12325.8 EEB07919.1 - 1.3 9.3 16.1 0.46 10.7 12.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 EEB07919.1 - 2 8.0 10.4 4.4 6.8 10.4 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 EEB07919.1 - 2.8 6.4 9.5 4.8 5.6 9.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 EEB07919.1 - 3.7 7.4 10.8 6 6.7 2.4 2.9 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EEB07919.1 - 5.1 7.6 18.8 10 6.6 17.3 2.4 2 1 0 2 2 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 EEB07919.1 - 5.6 7.4 14.2 12 6.3 14.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 EEB07919.1 - 7.7 6.3 16.4 2.9 7.7 13.2 1.9 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH NatB_MDM20 PF09797.9 EEB07920.1 - 1.9e-73 247.6 10.4 3.4e-73 246.8 10.4 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EEB07920.1 - 0.0033 17.9 1.4 0.38 11.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat SURF1 PF02104.15 EEB07921.1 - 1.2e-41 142.9 0.1 1.5e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 SURF1 family Histone PF00125.24 EEB07922.1 - 5.5e-17 62.4 0.0 6.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EEB07922.1 - 6.9e-11 41.7 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EEB07922.1 - 0.0085 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 EEB07923.1 - 1.4e-74 250.8 0.0 1.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07923.1 - 4.7e-30 104.7 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07923.1 - 1.8e-05 24.2 0.0 6.4e-05 22.4 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEB07923.1 - 0.00071 18.6 0.4 0.026 13.5 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EEB07923.1 - 0.00083 19.4 0.0 0.0029 17.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEB07923.1 - 0.0031 16.6 0.0 0.0067 15.5 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 WW PF00397.26 EEB07924.1 - 4.8e-08 32.9 2.4 4.8e-08 32.9 2.4 2.1 2 0 0 2 2 2 1 WW domain EMC3_TMCO1 PF01956.16 EEB07924.1 - 0.0073 16.1 0.0 0.0098 15.6 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like CDC50 PF03381.15 EEB07925.1 - 1e-89 300.8 0.5 1.2e-89 300.5 0.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family F-112 PF09645.10 EEB07926.1 - 0.018 15.1 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 F-112 protein DnaJ PF00226.31 EEB07927.1 - 8.2e-19 67.5 1.3 2.5e-18 65.9 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain CotJB PF12652.7 EEB07927.1 - 0.087 13.1 1.4 0.39 11.0 0.1 2.7 3 0 0 3 3 3 0 CotJB protein Ribosomal_S15 PF00312.22 EEB07928.1 - 2.6e-27 94.8 9.5 4.8e-27 94.0 1.2 2.7 3 0 0 3 3 3 2 Ribosomal protein S15 HTH_5 PF01022.20 EEB07928.1 - 0.17 11.8 1.4 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF1104 PF06518.11 EEB07928.1 - 0.64 10.4 4.4 1.5 9.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Dor1 PF04124.12 EEB07929.1 - 3.8e-35 121.2 15.9 6.2e-35 120.5 15.9 1.3 1 0 0 1 1 1 1 Dor1-like family MnmE_helical PF12631.7 EEB07929.1 - 0.15 12.2 2.0 0.24 11.5 0.1 2.3 1 1 1 2 2 2 0 MnmE helical domain Aminotran_1_2 PF00155.21 EEB07930.2 - 6e-65 219.8 0.0 7.3e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEB07930.2 - 0.014 14.0 0.0 0.052 12.1 0.0 1.9 2 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Glycos_transf_1 PF00534.20 EEB07931.1 - 2.8e-27 95.3 0.0 2.6e-25 89.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB07931.1 - 2.1e-15 57.2 0.0 3.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EEB07931.1 - 3.4e-11 43.7 0.0 8.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEB07931.1 - 0.0097 16.4 0.0 0.024 15.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EEB07931.1 - 0.021 15.2 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Alpha-amylase PF00128.24 EEB07932.1 - 3.4e-18 66.3 1.1 2e-14 53.9 0.0 3.7 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EEB07932.1 - 4.8e-13 49.4 0.0 8.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EEB07932.1 - 6.3e-10 38.8 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEB07932.1 - 1.2e-06 28.9 0.0 2.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB07932.1 - 0.0076 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Actin PF00022.19 EEB07933.1 - 9.6e-27 93.6 0.0 1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Actin Forkhead PF00250.18 EEB07934.1 - 2.1e-32 111.2 0.3 3.9e-32 110.4 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 EEB07935.1 - 6.5e-72 242.1 0.0 8.4e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07935.1 - 1.8e-35 122.5 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB07935.1 - 0.00034 20.0 0.0 0.00069 19.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEB07935.1 - 0.0026 16.8 0.0 0.033 13.1 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EEB07935.1 - 0.0068 16.1 0.1 3.4 7.2 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB07935.1 - 0.024 14.6 0.3 0.094 12.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEB07935.1 - 0.093 12.1 0.3 0.22 10.9 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family eIF2A PF08662.11 EEB07936.1 - 0.00024 21.0 0.2 0.0096 15.8 0.0 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.13 EEB07936.1 - 0.055 12.2 0.2 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Vps16, N-terminal region GCS PF03074.16 EEB07936.1 - 0.086 12.2 0.3 0.14 11.5 0.1 1.5 2 0 0 2 2 2 0 Glutamate-cysteine ligase DLH PF01738.18 EEB07937.1 - 2.3e-20 73.1 0.0 2.7e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EEB07937.1 - 0.0015 19.1 0.1 0.002 18.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Transket_pyr PF02779.24 EEB07938.1 - 9.4e-43 145.9 0.0 1.5e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEB07938.1 - 1.9e-37 127.9 0.1 4.5e-37 126.7 0.1 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EEB07938.1 - 0.027 14.7 0.1 0.083 13.2 0.0 1.8 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II MRP-S33 PF08293.11 EEB07939.2 - 2.6e-07 30.8 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.15 EEB07940.2 - 2.2e-66 223.5 12.5 5.8e-66 222.1 12.5 1.8 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3043 PF11241.8 EEB07940.2 - 0.19 11.7 4.9 0.54 10.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) FAT PF02259.23 EEB07941.2 - 5.6e-95 318.5 0.9 5.6e-95 318.5 0.9 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EEB07941.2 - 1.2e-64 218.6 0.3 2.9e-64 217.3 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EEB07941.2 - 6.8e-49 165.9 10.6 2.4e-48 164.1 0.1 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EEB07941.2 - 2e-37 127.6 0.7 2e-37 127.6 0.7 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EEB07941.2 - 1.3e-18 67.1 7.2 0.0016 18.8 0.1 8.8 6 1 2 9 9 9 4 HEAT repeats FATC PF02260.20 EEB07941.2 - 1.1e-16 60.3 0.2 2.4e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EEB07941.2 - 2.1e-14 52.3 17.3 0.012 15.8 0.0 12.1 12 0 0 12 12 11 3 HEAT repeat HEAT_EZ PF13513.6 EEB07941.2 - 4.2e-07 30.3 13.2 0.0075 16.8 0.1 8.1 8 1 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.8 EEB07941.2 - 3.2e-05 23.6 5.8 13 5.3 0.0 6.4 5 1 1 6 6 6 0 CLASP N terminal Cnd1 PF12717.7 EEB07941.2 - 5.5e-05 23.3 5.7 1.3 9.1 0.2 5.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EEB07941.2 - 0.0023 17.1 9.1 1.3 8.0 0.1 5.0 5 1 0 5 5 5 2 Interferon-related developmental regulator (IFRD) MOR2-PAG1_C PF14225.6 EEB07941.2 - 0.0038 17.1 1.0 0.011 15.6 0.2 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal Sec7_N PF12783.7 EEB07941.2 - 0.13 12.1 8.2 0.59 10.0 0.0 5.1 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ANAPC3 PF12895.7 EEB07941.2 - 0.53 10.5 8.4 1 9.6 0.3 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TB2_DP1_HVA22 PF03134.19 EEB07942.1 - 9.8e-20 70.3 3.6 1.8e-19 69.4 3.6 1.5 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 EEB07943.1 - 2.7e-88 293.9 0.0 3.6e-88 293.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.9 EEB07944.1 - 5.2e-104 348.3 0.0 7.3e-104 347.8 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EEB07944.1 - 5.1e-25 87.9 0.0 8.4e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DJ-1_PfpI PF01965.24 EEB07944.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family BPL_C PF02237.17 EEB07944.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 EEB07944.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain LSM PF01423.22 EEB07945.1 - 6.5e-18 64.2 0.0 8.5e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB07945.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EEB07945.1 - 0.13 11.9 0.5 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Hfq protein tRNA-synt_1c PF00749.21 EEB07946.1 - 7e-93 311.0 0.0 8.9e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Toprim_C_rpt PF13368.6 EEB07946.1 - 0.16 12.0 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Ras PF00071.22 EEB07947.2 - 2.2e-53 180.2 0.0 2.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB07947.2 - 3.2e-33 114.5 0.0 4.6e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB07947.2 - 5e-13 48.9 0.0 6.1e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEB07947.2 - 8.1e-08 32.4 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EEB07947.2 - 1.5e-05 24.9 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EEB07947.2 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEB07947.2 - 4e-05 23.3 0.0 0.0021 17.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EEB07947.2 - 0.00065 20.1 0.0 0.00085 19.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEB07947.2 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EEB07947.2 - 0.0034 17.1 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EEB07947.2 - 0.0069 16.0 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EEB07947.2 - 0.0069 15.7 0.1 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Septin ATPase_2 PF01637.18 EEB07947.2 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EEB07947.2 - 0.019 15.2 0.0 0.044 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EEB07947.2 - 0.02 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EEB07947.2 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EEB07947.2 - 0.047 13.1 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EEB07947.2 - 0.048 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EEB07947.2 - 0.049 14.2 0.1 0.057 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EEB07947.2 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 EEB07947.2 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 EEB07947.2 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EEB07947.2 - 0.11 12.8 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.22 EEB07947.2 - 0.13 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EEB07947.2 - 0.17 11.9 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EEB07947.2 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 NTPase MAP65_ASE1 PF03999.12 EEB07948.1 - 1.4e-91 308.1 26.5 1.8e-91 307.7 26.5 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) CK2S PF15011.6 EEB07948.1 - 0.00034 20.5 1.1 0.0016 18.4 1.1 2.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate Syntaxin_2 PF14523.6 EEB07948.1 - 7.8 6.9 7.6 0.42 11.0 0.2 2.8 3 0 0 3 3 3 0 Syntaxin-like protein Serinc PF03348.15 EEB07950.1 - 3.3e-123 411.8 24.2 3.8e-123 411.6 24.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) G0-G1_switch_2 PF15103.6 EEB07950.1 - 0.38 11.2 1.5 6.7 7.2 0.1 3.0 3 0 0 3 3 3 0 G0/G1 switch protein 2 HA2 PF04408.23 EEB07951.1 - 2.3e-22 79.3 0.0 2.3e-22 79.3 0.0 4.0 3 2 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEB07951.1 - 3.2e-13 50.0 0.3 2.8e-11 43.7 0.0 3.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEB07951.1 - 1e-07 32.2 0.1 2.8e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEB07951.1 - 4.4e-06 26.6 0.4 2.3e-05 24.2 0.1 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EEB07951.1 - 0.00019 21.8 0.0 0.0049 17.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEB07951.1 - 0.00032 21.0 1.4 0.0049 17.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Hormone_recep PF00104.30 EEB07951.1 - 0.0017 17.9 0.1 0.0017 17.9 0.1 2.1 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor AAA_33 PF13671.6 EEB07951.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 EEB07953.1 - 3e-45 154.7 34.3 3e-45 154.7 34.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB07953.1 - 4.4e-09 35.7 23.2 2.2e-08 33.4 23.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.12 EEB07953.1 - 0.00085 18.0 0.0 0.0018 16.9 0.0 1.5 1 0 0 1 1 1 1 Ferroportin1 (FPN1) TMEM208_SND2 PF05620.11 EEB07953.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2423 PF10338.9 EEB07954.1 - 1.3e-17 63.7 0.7 1.3e-17 63.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Mrr_N PF14338.6 EEB07954.1 - 0.0013 18.9 0.4 0.0033 17.5 0.2 1.7 1 1 1 2 2 2 1 Mrr N-terminal domain WD40 PF00400.32 EEB07955.1 - 2.5e-29 100.9 8.6 4.8e-06 27.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07955.1 - 2.3e-09 37.4 0.1 0.43 10.9 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB07955.1 - 2.6e-06 26.4 4.0 0.064 11.9 0.1 3.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EEB07955.1 - 0.00027 20.4 0.0 0.0085 15.5 0.0 2.8 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EEB07955.1 - 0.014 14.3 0.2 0.079 11.9 0.0 2.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EEB07955.1 - 0.3 10.8 2.0 18 5.0 0.0 3.2 2 1 0 3 3 3 0 TUP1-like enhancer of split Glyco_transf_15 PF01793.16 EEB07956.1 - 7e-95 318.0 13.0 1.1e-94 317.3 13.0 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.25 EEB07957.2 - 3.1e-40 138.2 0.0 2.2e-39 135.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB07957.2 - 2.3e-17 63.1 0.0 4e-15 55.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 EEB07957.2 - 4.3e-05 23.6 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 PH domain RabGAP-TBC PF00566.18 EEB07958.1 - 2.9e-37 128.4 0.1 4.1e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain P21-Arc PF04062.14 EEB07959.1 - 3.2e-76 255.2 0.0 3.5e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit N2227 PF07942.12 EEB07960.2 - 4e-104 347.6 0.0 4.8e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EEB07960.2 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB07960.2 - 0.052 14.2 0.0 0.94 10.2 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEB07960.2 - 0.12 13.1 0.0 0.77 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CH PF00307.31 EEB07961.1 - 1.4e-78 260.2 0.3 8.6e-20 70.9 0.0 4.5 5 0 0 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EEB07961.1 - 5.7e-05 23.5 0.2 0.00031 21.1 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB07961.1 - 0.0001 21.6 0.0 3.5 7.4 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EEB07961.1 - 0.002 17.9 0.1 2 8.5 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 EEB07961.1 - 0.009 15.8 0.0 4.5 7.2 0.0 3.7 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_8 PF13833.6 EEB07961.1 - 0.0095 15.8 0.0 1.5 8.7 0.0 2.8 1 1 1 2 2 2 1 EF-hand domain pair Dfp1_Him1_M PF08630.10 EEB07963.1 - 8.7e-25 87.4 0.0 2.4e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EEB07963.1 - 1e-16 60.8 1.9 2.2e-16 59.7 1.9 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EEB07963.1 - 0.00055 20.3 0.1 0.0011 19.2 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEB07963.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 EEB07963.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Ribosomal_60s PF00428.19 EEB07963.1 - 0.43 11.2 10.3 1.2 9.7 10.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUDIX PF00293.28 EEB07964.1 - 3.1e-12 46.7 0.0 5.5e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EEB07964.1 - 5.4e-10 39.8 0.0 1.1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EEB07964.1 - 0.00061 19.4 1.9 0.0051 16.4 0.7 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Myb_DNA-bind_2 PF08914.11 EEB07965.2 - 3.5e-12 46.3 0.3 8.7e-12 45.1 0.3 1.7 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EEB07965.2 - 0.00034 21.0 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 EEB07965.2 - 0.00054 20.5 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Rap1, DNA-binding BTB PF00651.31 EEB07966.2 - 4.1e-07 30.2 0.1 8.6e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain RAC_head PF16717.5 EEB07967.1 - 3.7e-25 88.8 1.2 3.7e-25 88.8 1.2 3.1 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EEB07967.1 - 4e-19 68.5 4.0 1e-18 67.2 4.0 1.7 1 0 0 1 1 1 1 DnaJ domain DAG_kinase_N PF14513.6 EEB07967.1 - 0.0012 19.0 1.8 0.0012 19.0 1.8 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase N-terminus Presenilin PF01080.17 EEB07967.1 - 0.086 11.6 11.0 0.17 10.6 11.0 1.4 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EEB07967.1 - 0.67 7.8 5.5 1.4 6.7 5.6 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 EEB07967.1 - 4.4 6.1 4.8 4.9 5.9 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CBFD_NFYB_HMF PF00808.23 EEB07968.1 - 8.6e-20 70.8 0.9 8.6e-20 70.8 0.9 2.4 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB07968.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ISN1 PF06437.11 EEB07969.1 - 9.7e-160 531.9 0.0 1.1e-159 531.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Swi3 PF07962.12 EEB07970.2 - 1.6e-30 104.9 0.4 2.2e-30 104.4 0.4 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 adh_short PF00106.25 EEB07971.1 - 2.1e-42 144.8 0.5 2.5e-42 144.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB07971.1 - 3.7e-31 108.5 0.4 4.6e-31 108.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB07971.1 - 1.9e-08 34.4 0.4 2.8e-08 33.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Vps4_C PF09336.10 EEB07971.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Eno-Rase_NADH_b PF12242.8 EEB07971.1 - 0.05 13.4 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Complex1_LYR PF05347.15 EEB07972.1 - 0.00048 20.1 2.0 0.00072 19.6 2.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEB07972.1 - 0.027 15.2 0.2 0.036 14.8 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DIRP PF06584.13 EEB07972.1 - 0.096 12.9 0.7 0.15 12.3 0.7 1.4 1 1 0 1 1 1 0 DIRP Exonuc_VII_S PF02609.16 EEB07972.1 - 0.1 12.6 0.2 1.9 8.6 0.0 2.3 2 1 0 2 2 2 0 Exonuclease VII small subunit DotD PF16816.5 EEB07972.1 - 0.12 12.3 0.1 0.4 10.7 0.1 1.7 1 1 1 2 2 2 0 DotD protein DNA_pol3_delt_C PF14840.6 EEB07972.1 - 0.12 12.7 0.2 0.15 12.4 0.2 1.1 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term APG9 PF04109.16 EEB07973.1 - 3.6e-180 600.1 18.7 4.2e-180 599.9 18.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_fiss_reg PF05308.11 EEB07974.1 - 0.061 13.4 2.2 0.05 13.7 1.0 1.5 1 1 1 2 2 2 0 Mitochondrial fission regulator HPPK PF01288.20 EEB07974.1 - 0.075 13.6 0.1 0.1 13.1 0.1 1.3 1 1 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Cys_Met_Meta_PP PF01053.20 EEB07975.1 - 6.4e-38 130.3 0.0 8.5e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEB07975.1 - 0.0042 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Tox-ODYAM1 PF15642.6 EEB07975.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Nucleoporin_FG PF13634.6 EEB07976.1 - 0.00026 21.8 135.5 0.64 10.9 21.7 5.5 1 1 2 3 3 3 2 Nucleoporin FG repeat region OmpH PF03938.14 EEB07976.1 - 0.6 10.4 5.7 0.072 13.4 0.9 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MAM33 PF02330.16 EEB07977.1 - 5.4e-11 42.9 0.4 7.4e-11 42.4 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein AKAP7_NLS PF10469.9 EEB07979.1 - 1.3e-25 90.5 0.0 1.6e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain TFIID_NTD2 PF04494.15 EEB07980.1 - 4.2e-41 140.2 0.5 4.2e-41 140.2 0.5 2.0 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EEB07980.1 - 2.4e-37 126.2 19.9 1.4e-07 32.1 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB07980.1 - 2.1e-10 40.8 0.0 0.33 11.3 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEB07980.1 - 3.5e-07 29.8 0.1 0.27 10.5 0.0 4.3 2 1 1 4 4 4 2 WD40-like domain LisH PF08513.11 EEB07980.1 - 0.00028 20.7 0.0 0.00092 19.1 0.0 2.0 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EEB07980.1 - 0.001 17.8 0.0 0.51 8.9 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEB07980.1 - 0.019 14.0 0.1 19 4.1 0.0 3.5 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrolase_6 PF13344.6 EEB07981.1 - 2.1e-30 104.8 0.0 3.5e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEB07981.1 - 2.7e-14 53.0 0.0 4.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEB07981.1 - 1.2e-09 38.8 0.0 2.6e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB07981.1 - 2.4e-06 27.8 0.1 0.068 13.3 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EEB07981.1 - 0.12 12.0 0.0 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Cep57_CLD_2 PF14197.6 EEB07982.1 - 0.0091 16.1 1.6 2 8.5 0.3 2.5 2 0 0 2 2 2 2 Centrosome localisation domain of PPC89 CREPT PF16566.5 EEB07982.1 - 0.033 14.4 1.8 1.2 9.3 0.7 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FliD_C PF07195.12 EEB07982.1 - 0.15 11.5 0.5 0.21 11.0 0.5 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Acetyltransf_1 PF00583.25 EEB07985.1 - 2.3e-13 50.4 0.1 4.5e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB07985.1 - 1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCCH PF00642.24 EEB07985.1 - 1.4e-09 37.6 2.9 3.2e-09 36.5 2.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acetyltransf_7 PF13508.7 EEB07985.1 - 3.6e-09 36.9 0.1 8.3e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3HC4_3 PF13920.6 EEB07985.1 - 9.6e-07 28.6 7.7 2.4e-06 27.3 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 EEB07985.1 - 5.1e-06 26.3 5.7 1.1e-05 25.3 5.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EEB07985.1 - 5.4e-06 26.4 5.1 1.8e-05 24.8 5.1 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 EEB07985.1 - 7.4e-06 25.7 12.0 1.8e-05 24.5 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_4 PF13420.7 EEB07985.1 - 1.8e-05 24.9 0.0 3.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3HC4 PF00097.25 EEB07985.1 - 0.00026 20.8 13.4 0.00061 19.6 13.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 EEB07985.1 - 0.00034 20.3 3.0 0.00034 20.3 3.0 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_5 PF14634.6 EEB07985.1 - 0.00045 20.1 11.6 0.001 19.0 11.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEB07985.1 - 0.0006 19.8 11.0 0.0016 18.4 11.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEB07985.1 - 0.0016 18.7 10.3 0.0039 17.5 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EEB07985.1 - 0.0066 16.3 8.4 0.014 15.2 8.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FR47 PF08445.10 EEB07985.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein TMEM247 PF15444.6 EEB07985.1 - 0.17 11.9 0.8 0.4 10.7 0.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 zf-CCCH_2 PF14608.6 EEB07985.1 - 0.28 11.7 2.2 0.65 10.6 2.2 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Zn-ribbon_8 PF09723.10 EEB07985.1 - 0.52 10.5 3.6 1.5 9.0 3.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 EEB07985.1 - 0.87 9.8 9.7 2 8.6 9.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EEB07985.1 - 3.6 7.5 7.6 10 6.1 7.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.17 EEB07986.2 - 2.5e-12 46.7 0.2 4.5e-12 45.9 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEB07986.2 - 4.9e-08 33.3 0.1 8.3e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EEB07986.2 - 0.028 14.5 0.1 0.064 13.4 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif SAM_3 PF18016.1 EEB07986.2 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ATP-synt_DE_N PF02823.16 EEB07987.1 - 3.5e-14 52.5 0.0 5.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Mannosyl_trans PF05007.13 EEB07988.1 - 6.8e-79 265.4 23.6 6.8e-79 265.4 23.6 2.1 3 0 0 3 3 3 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EEB07988.1 - 5.1e-07 29.1 22.7 5.1e-07 29.1 22.7 2.5 2 2 0 2 2 2 1 GPI transamidase subunit PIG-U DUF758 PF05527.11 EEB07988.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) ADIP PF11559.8 EEB07989.1 - 2.1e-19 70.1 17.0 2.1e-19 70.1 17.0 3.2 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Sucrose_synth PF00862.19 EEB07989.1 - 0.0035 15.7 0.6 0.0035 15.7 0.6 1.9 2 0 0 2 2 2 1 Sucrose synthase DUF2381 PF09544.10 EEB07989.1 - 0.016 14.8 4.5 0.039 13.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) Tli4_C PF18426.1 EEB07989.1 - 0.26 11.6 4.6 0.26 11.6 2.6 1.9 1 1 1 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain UPF0242 PF06785.11 EEB07989.1 - 2.9 8.0 39.4 0.17 12.0 19.4 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EEB07989.1 - 3.9 8.2 24.7 2 9.1 2.3 3.8 2 2 1 3 3 3 0 Initiation control protein YabA MscL PF01741.18 EEB07990.2 - 0.39 11.0 0.0 0.39 11.0 0.0 2.3 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Leo1 PF04004.13 EEB07991.2 - 1.9e-39 135.1 0.6 1.9e-39 135.1 0.6 2.4 2 1 0 2 2 2 1 Leo1-like protein SHR3_chaperone PF08229.11 EEB07991.2 - 4.5 6.2 4.1 12 4.8 4.1 1.7 1 0 0 1 1 1 0 ER membrane protein SH3 WH2 PF02205.20 EEB07992.1 - 3e-11 42.8 1.4 8.9e-11 41.3 0.7 2.0 2 0 0 2 2 2 1 WH2 motif TFIIB PF00382.19 EEB07993.1 - 1.7e-34 117.7 4.1 4.6e-18 65.0 0.1 3.1 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EEB07993.1 - 2.6e-30 104.8 4.2 2.6e-30 104.8 4.2 2.9 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EEB07993.1 - 3.2e-09 36.2 3.4 7.7e-09 34.9 3.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EEB07993.1 - 9.7e-05 22.1 0.2 0.27 11.0 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.11 EEB07993.1 - 0.58 10.1 2.9 1.8 8.6 2.9 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rhomboid PF01694.22 EEB07994.1 - 1.9e-23 83.1 13.5 3.7e-23 82.2 13.5 1.4 1 0 0 1 1 1 1 Rhomboid family Ribosomal_L1 PF00687.21 EEB07995.1 - 1.5e-46 158.7 0.7 1.8e-46 158.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SMI1_KNR4 PF09346.10 EEB07996.1 - 2.5e-30 105.6 0.0 5e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PDT PF00800.18 EEB07997.1 - 4.6e-53 179.8 0.0 6e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Gar1 PF04410.14 EEB07998.1 - 1.5e-39 135.3 0.3 1.5e-39 135.3 0.3 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region TFIIF_alpha PF05793.12 EEB07998.1 - 0.39 9.2 18.4 0.3 9.6 9.2 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 EEB07998.1 - 0.89 9.6 15.6 0.67 10.0 0.9 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Metallophos PF00149.28 EEB07999.2 - 4.1e-39 135.2 0.2 5.3e-39 134.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEB07999.2 - 1.7e-23 82.7 0.6 3.7e-23 81.7 0.6 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L29e PF01779.17 EEB08000.1 - 8.9e-21 73.9 15.1 1.1e-20 73.6 15.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family POB3_N PF17292.2 EEB08001.1 - 2.7e-29 101.4 0.0 1.1e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EEB08001.1 - 7.1e-28 96.3 0.0 2.1e-27 94.8 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EEB08001.1 - 9.9e-26 90.0 0.2 6.2e-25 87.4 0.0 2.3 2 1 0 2 2 2 1 Histone chaperone Rttp106-like NOA36 PF06524.12 EEB08001.1 - 6.4 6.0 8.5 9.9 5.4 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EEB08002.1 - 7.6e-05 22.2 0.0 0.0019 17.6 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 EEB08002.1 - 0.0072 16.5 0.3 1 9.6 0.0 3.3 4 0 0 4 4 4 1 POLO box duplicated region AXH PF08517.12 EEB08002.1 - 0.025 15.1 0.7 2.3 8.8 0.0 3.8 4 0 0 4 4 4 0 Ataxin-1 and HBP1 module (AXH) WD40 PF00400.32 EEB08003.2 - 2e-17 63.2 18.2 6.5e-06 26.8 0.4 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08003.2 - 4.9e-05 23.6 0.3 0.0021 18.4 0.1 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TTD PF12148.8 EEB08003.2 - 0.012 15.5 0.3 0.028 14.3 0.3 1.6 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 DUF4611 PF15387.6 EEB08003.2 - 0.19 12.0 6.1 0.46 10.7 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DSPc PF00782.20 EEB08004.1 - 2.8e-08 33.7 0.0 5.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB08004.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EEB08004.1 - 0.00046 20.2 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EEB08004.1 - 0.0018 18.4 0.0 0.0064 16.6 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EEB08004.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family RNB PF00773.19 EEB08005.2 - 6.7e-44 150.5 1.1 9.7e-44 150.0 0.2 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EEB08005.2 - 4.3e-21 74.7 0.0 8.9e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EEB08005.2 - 6.6e-14 52.0 0.0 2e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EEB08005.2 - 0.00029 21.0 0.0 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 EEB08005.2 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Glyco_transf_43 PF03360.16 EEB08005.2 - 0.024 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 43 DUF4704 PF15787.5 EEB08005.2 - 0.039 13.2 0.4 0.066 12.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Ribosomal_L36e PF01158.18 EEB08006.1 - 8.1e-41 138.2 2.2 8.8e-41 138.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 EEB08006.1 - 0.0082 16.3 0.1 0.0094 16.1 0.1 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain PBS_linker_poly PF00427.21 EEB08006.1 - 0.084 12.9 0.2 0.099 12.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DnaJ_C PF01556.18 EEB08008.1 - 2.2e-33 115.5 0.0 3.2e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEB08008.1 - 1.6e-20 73.0 1.2 2.5e-20 72.3 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEB08008.1 - 3.2e-12 46.6 18.4 5.5e-12 45.9 18.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEB08008.1 - 0.03 14.3 1.9 0.03 14.3 1.9 3.5 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein PDZ_6 PF17820.1 EEB08008.1 - 0.052 13.4 1.1 4.6 7.2 0.3 3.3 4 0 0 4 4 4 0 PDZ domain DZR PF12773.7 EEB08008.1 - 1.5 8.9 7.7 1.6 8.8 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1356 PF07092.12 EEB08008.1 - 4.3 6.5 9.3 20 4.3 1.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) ATG16 PF08614.11 EEB08009.1 - 7.3e-10 39.4 14.0 1.6e-05 25.3 11.1 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) PHM7_cyt PF14703.6 EEB08009.1 - 0.0018 18.6 1.5 0.0022 18.2 1.5 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Pox_F11 PF04943.12 EEB08009.1 - 0.017 14.2 2.0 0.019 14.0 2.0 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein CaMBD PF02888.16 EEB08009.1 - 0.034 14.3 1.6 0.067 13.4 1.6 1.5 1 0 0 1 1 1 0 Calmodulin binding domain DUF3560 PF12083.8 EEB08009.1 - 0.042 14.0 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) TMPIT PF07851.13 EEB08009.1 - 0.17 11.1 5.3 0.25 10.5 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 EEB08009.1 - 0.31 11.1 13.9 0.058 13.5 10.0 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.6 EEB08009.1 - 0.39 10.7 16.9 0.35 10.9 7.2 2.3 1 1 1 2 2 2 0 FlxA-like protein PCRF PF03462.18 EEB08009.1 - 0.55 10.1 6.2 0.98 9.2 6.2 1.4 1 0 0 1 1 1 0 PCRF domain DUF4140 PF13600.6 EEB08009.1 - 3.4 8.2 8.9 3.9 8.0 2.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2968 PF11180.8 EEB08009.1 - 4.7 6.8 15.0 12 5.5 11.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) SlyX PF04102.12 EEB08009.1 - 5.9 7.6 14.6 2.9 8.6 2.4 2.5 1 1 1 2 2 2 0 SlyX Ras PF00071.22 EEB08010.1 - 1.4e-57 193.8 0.1 1.7e-57 193.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB08010.1 - 2.5e-33 114.8 0.0 3.7e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB08010.1 - 7.3e-12 45.1 0.0 9.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEB08010.1 - 3.5e-08 33.5 0.0 6.7e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEB08010.1 - 2.9e-07 30.1 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEB08010.1 - 1.4e-06 28.0 0.0 7.3e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EEB08010.1 - 1.2e-05 25.2 0.4 0.001 18.9 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EEB08010.1 - 0.00013 21.9 0.4 0.0029 17.6 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EEB08010.1 - 0.0013 19.2 0.0 0.0019 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EEB08010.1 - 0.0016 17.8 0.2 0.0074 15.6 0.1 1.9 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 EEB08010.1 - 0.003 17.3 0.2 0.0089 15.8 0.1 1.9 1 1 0 2 2 2 1 AAA domain cobW PF02492.19 EEB08010.1 - 0.0033 17.0 0.1 0.014 15.0 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EEB08010.1 - 0.0045 16.9 0.4 0.0081 16.1 0.1 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EEB08010.1 - 0.0053 17.0 0.0 0.018 15.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.20 EEB08010.1 - 0.0057 15.9 1.0 0.16 11.1 0.2 2.3 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 EEB08010.1 - 0.0071 16.1 0.1 0.083 12.6 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EEB08010.1 - 0.0079 15.6 0.1 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EEB08010.1 - 0.018 14.6 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EEB08010.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EEB08010.1 - 0.031 14.7 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EEB08010.1 - 0.047 14.2 0.2 0.058 13.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 EEB08010.1 - 0.05 13.5 0.2 0.081 12.8 0.0 1.4 2 0 0 2 2 1 0 NTPase AAA_5 PF07728.14 EEB08010.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EEB08010.1 - 0.062 12.7 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PseudoU_synth_2 PF00849.22 EEB08010.1 - 0.073 13.2 0.0 0.088 12.9 0.0 1.3 1 1 0 1 1 1 0 RNA pseudouridylate synthase DAP3 PF10236.9 EEB08010.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.26 EEB08010.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain EamA PF00892.20 EEB08011.1 - 3.7e-12 46.6 28.6 1.7e-05 25.0 2.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EEB08011.1 - 9.8e-07 28.6 14.4 9.8e-07 28.6 14.4 1.7 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 EEB08011.1 - 0.0017 17.6 4.9 0.0017 17.6 4.9 2.1 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 EEB08011.1 - 0.0047 16.7 2.5 0.0047 16.7 2.5 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF3955) TPT PF03151.16 EEB08011.1 - 0.0052 16.2 8.4 0.011 15.1 8.4 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family GARS_A PF01071.19 EEB08013.2 - 4.6e-81 271.3 0.0 7.3e-81 270.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EEB08013.2 - 3.6e-37 127.9 0.0 1e-36 126.4 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EEB08013.2 - 1.4e-34 118.7 0.1 6.3e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EEB08013.2 - 7.8e-30 103.0 0.5 2.2e-29 101.6 0.5 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EEB08013.2 - 4.2e-16 59.4 0.7 1.9e-15 57.3 0.7 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EEB08013.2 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.11 EEB08013.2 - 0.064 12.8 0.2 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GHMP_kinases_N PF00288.26 EEB08014.1 - 7e-10 39.0 0.1 1.8e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEB08014.1 - 1.5e-05 25.2 0.1 5.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Mss4 PF04421.13 EEB08015.1 - 2.6e-27 94.8 0.0 3.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Mss4 protein Forkhead PF00250.18 EEB08016.1 - 6e-32 109.8 0.1 1.6e-31 108.4 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain RNA_pol_Rpb1_5 PF04998.17 EEB08017.1 - 6.5e-99 330.7 0.1 1.3e-98 329.7 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEB08017.1 - 3e-67 226.0 0.1 6.5e-67 224.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEB08017.1 - 2.2e-35 121.9 0.0 5.6e-35 120.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EEB08017.1 - 2.2e-34 119.2 0.1 4.8e-33 114.8 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EEB08017.1 - 1.1e-22 80.0 0.1 3.9e-22 78.2 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Actin PF00022.19 EEB08018.1 - 2.5e-149 497.4 0.0 1.1e-148 495.2 0.0 1.7 1 1 0 1 1 1 1 Actin muHD PF10291.9 EEB08019.1 - 3e-17 63.0 0.4 5.6e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EEB08019.1 - 3.6e-09 36.8 0.6 1.2e-08 35.1 0.6 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain JAB PF01398.21 EEB08020.1 - 3.8e-21 75.2 0.0 7.4e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEB08020.1 - 1.6e-18 67.2 0.1 2.9e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EEB08020.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Glyco_transf_8 PF01501.20 EEB08022.1 - 0.019 14.5 0.3 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 EEB08023.1 - 9.2e-06 25.4 0.5 0.00013 21.6 0.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Proteasome PF00227.26 EEB08024.1 - 9.8e-48 162.2 0.7 1.1e-47 162.0 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit Homoserine_dh PF00742.19 EEB08025.2 - 1.6e-52 177.9 0.0 2.4e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EEB08025.2 - 5.9e-17 62.4 0.0 4.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEB08025.2 - 0.039 13.3 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sec23_trunk PF04811.15 EEB08026.1 - 6.6e-69 232.2 0.1 1e-68 231.6 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEB08026.1 - 2.9e-30 104.9 1.0 5.6e-30 103.9 1.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEB08026.1 - 3e-24 84.8 0.1 7.6e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EEB08026.1 - 2.6e-15 56.1 0.0 7.5e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EEB08026.1 - 7.6e-14 51.5 6.3 1.6e-13 50.5 6.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 EEB08026.1 - 0.032 14.9 0.0 1.2 9.8 0.0 2.5 1 1 1 2 2 2 0 von Willebrand factor type A domain Vps36-NZF-N PF16988.5 EEB08026.1 - 0.032 13.6 0.1 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2838 PF10998.8 EEB08027.1 - 1.2e-40 138.2 8.3 1.2e-40 138.2 8.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) MAM33 PF02330.16 EEB08028.1 - 1.3e-53 182.1 12.9 1.5e-53 181.9 12.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Nrap_D4 PF17405.2 EEB08029.1 - 1.3e-50 171.7 0.0 2.4e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EEB08029.1 - 9.6e-49 165.3 1.1 2e-48 164.2 1.1 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 EEB08029.1 - 3e-41 141.0 0.3 5.5e-41 140.1 0.3 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EEB08029.1 - 3.4e-40 137.7 0.0 6.9e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 EEB08029.1 - 1.2e-33 116.0 1.8 8.6e-32 110.0 0.6 3.0 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 EEB08029.1 - 1.3e-27 96.7 0.0 2.6e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 DEAD PF00270.29 EEB08030.1 - 5.6e-42 143.5 0.0 7.9e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB08030.1 - 1.6e-27 96.0 1.3 1.4e-26 93.0 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08030.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EEB08030.1 - 0.02 14.2 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 EEB08030.1 - 0.14 12.1 0.4 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain COG6 PF06419.11 EEB08031.1 - 1.3e-108 363.9 27.0 1.6e-108 363.6 27.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF234 PF03008.14 EEB08031.1 - 0.00047 20.6 0.6 0.52 10.8 0.2 2.8 2 0 0 2 2 2 2 Archaea bacterial proteins of unknown function DUF885 PF05960.11 EEB08031.1 - 0.0069 16.1 1.9 0.0099 15.6 1.9 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Utp12 PF04003.12 EEB08031.1 - 0.3 11.4 7.0 16 5.9 1.2 4.4 3 1 1 4 4 4 0 Dip2/Utp12 Family Ribosomal_L27A PF00828.19 EEB08032.1 - 2.7e-21 76.6 0.0 3.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EEB08033.1 - 2.3e-44 151.7 0.0 7.8e-41 140.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08033.1 - 6e-14 51.9 0.0 6.8e-09 35.4 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EEB08033.1 - 2e-05 24.6 2.7 0.0023 17.9 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEB08033.1 - 4.5e-05 22.4 0.0 8.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EEB08033.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEB08033.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEB08033.1 - 0.11 12.1 0.6 0.31 10.6 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Cnd1 PF12717.7 EEB08034.1 - 2.9e-43 147.7 8.2 3.4e-41 141.0 0.6 3.8 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EEB08034.1 - 1.7e-31 109.3 0.2 4.3e-31 108.0 0.2 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EEB08034.1 - 9e-06 26.0 0.2 0.055 13.9 0.0 4.9 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EEB08034.1 - 9e-05 22.4 1.9 16 6.0 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 EEB08034.1 - 0.0038 17.4 0.1 0.69 10.1 0.0 3.6 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EEB08034.1 - 0.025 15.1 0.9 31 5.2 0.0 5.0 5 1 0 5 5 5 0 HEAT-like repeat TAF1_subA PF14929.6 EEB08034.1 - 0.048 13.1 5.8 0.053 12.9 0.1 3.0 3 0 0 3 3 3 0 TAF RNA Polymerase I subunit A TAN PF11640.8 EEB08034.1 - 8.3 6.5 9.2 2 8.5 0.5 3.5 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair LCAT PF02450.15 EEB08035.1 - 2.8e-122 408.7 0.0 3.6e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EEB08035.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EEB08035.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) LIDHydrolase PF10230.9 EEB08035.1 - 0.053 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EEB08035.1 - 0.092 12.0 0.2 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 2-oxoacid_dh PF00198.23 EEB08036.1 - 2.3e-80 269.4 0.0 3e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEB08036.1 - 1.7e-17 63.0 0.7 3.4e-17 62.1 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEB08036.1 - 0.0011 18.8 0.0 0.017 14.9 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 EEB08036.1 - 0.0044 17.0 0.1 0.03 14.3 0.0 2.1 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EEB08036.1 - 0.016 15.1 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein YL1 PF05764.13 EEB08036.1 - 0.018 15.2 1.1 0.022 14.9 1.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein OMPdecase PF00215.24 EEB08037.1 - 3.3e-81 272.2 0.0 3.8e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Redoxin PF08534.10 EEB08038.1 - 2e-30 105.4 0.1 2.2e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EEB08038.1 - 2e-10 40.7 0.0 2.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glycos_transf_3 PF00591.21 EEB08039.1 - 2.4e-83 279.6 0.0 3.3e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EEB08039.1 - 0.003 17.4 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Band_7 PF01145.25 EEB08040.2 - 1.9e-24 86.7 0.0 3.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EEB08040.2 - 7.5e-16 57.9 0.7 1.3e-15 57.2 0.2 1.7 2 0 0 2 2 2 1 C-terminal region of band_7 RLL PF10036.9 EEB08040.2 - 0.0038 17.1 5.7 0.0083 16.0 3.7 2.0 1 1 1 2 2 2 1 RNA transcription, translation and transport factor protein Band_7_1 PF13421.6 EEB08040.2 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family HrpF PF06266.12 EEB08040.2 - 0.13 12.5 1.2 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 HrpF protein Motile_Sperm PF00635.26 EEB08042.1 - 1.1e-23 83.1 0.1 2.1e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF812 PF05667.11 EEB08042.1 - 1.7 7.5 6.0 2.4 6.9 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CRAL_TRIO PF00650.20 EEB08044.1 - 1.2e-22 80.3 0.1 5.3e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEB08044.1 - 1.3e-05 25.3 0.2 4.7e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEB08044.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain UbiA PF01040.18 EEB08045.1 - 1.1e-49 169.0 14.6 1.7e-49 168.4 14.6 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PfkB PF00294.24 EEB08046.1 - 9.9e-70 235.2 3.1 1.1e-69 235.1 3.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEB08046.1 - 1.2e-07 31.4 0.1 2e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase zf-RING_2 PF13639.6 EEB08047.1 - 2.1e-10 40.7 8.7 1.1e-09 38.4 9.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEB08047.1 - 4.4e-08 32.8 8.4 7.3e-08 32.2 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB08047.1 - 1.6e-07 31.0 8.3 3.1e-07 30.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB08047.1 - 2.6e-07 30.3 9.4 2.6e-07 30.3 9.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEB08047.1 - 7.4e-05 23.0 8.7 0.00027 21.2 8.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEB08047.1 - 9.8e-05 22.3 6.4 9.8e-05 22.3 6.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEB08047.1 - 0.0027 17.6 7.5 0.0046 16.9 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EEB08047.1 - 0.0074 16.0 5.9 0.023 14.4 5.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 EEB08047.1 - 0.023 14.6 10.5 0.043 13.7 10.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cyclotide PF03784.13 EEB08047.1 - 0.18 11.9 1.1 0.38 10.9 1.1 1.5 1 0 0 1 1 1 0 Cyclotide family zf-P11 PF03854.14 EEB08047.1 - 1.7 8.4 8.0 6.3 6.5 8.1 1.9 1 1 0 1 1 1 0 P-11 zinc finger Ribosomal_L13 PF00572.18 EEB08048.1 - 5.5e-47 159.1 0.0 7.4e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNase_PH PF01138.21 EEB08050.2 - 1.6e-32 112.8 0.0 2.2e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEB08050.2 - 3.7e-06 26.9 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2000 PF09391.10 EEB08050.2 - 0.048 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) BclA_C PF18573.1 EEB08050.2 - 0.12 12.3 0.3 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 BclA C-terminal domain ACPS PF01648.20 EEB08051.1 - 3.2e-15 56.2 0.1 3.9e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.12 EEB08052.1 - 5.1e-98 328.6 2.6 5.6e-97 325.1 2.6 1.9 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 EEB08052.1 - 0.0068 16.3 0.1 0.081 12.8 0.0 2.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 EEB08052.1 - 0.019 15.6 0.1 0.07 13.8 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal Ribosomal_S25 PF03297.15 EEB08052.1 - 0.035 14.3 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 S25 ribosomal protein PadR PF03551.14 EEB08052.1 - 0.076 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MarR PF01047.22 EEB08052.1 - 0.12 12.3 0.2 1.1 9.2 0.1 2.5 3 0 0 3 3 3 0 MarR family EndIII_4Fe-2S PF10576.9 EEB08052.1 - 0.36 11.2 1.7 0.71 10.3 1.7 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Penicillinase_R PF03965.16 EEB08052.1 - 0.37 11.2 2.2 7.2 7.0 0.0 2.6 2 1 1 3 3 3 0 Penicillinase repressor Nup192 PF11894.8 EEB08053.1 - 8.2e-204 679.7 40.1 1e-203 679.4 40.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 GATA PF00320.27 EEB08054.1 - 6.3e-10 38.5 3.6 1.8e-09 37.0 3.6 1.9 1 0 0 1 1 1 1 GATA zinc finger PP2C PF00481.21 EEB08055.1 - 8.1e-75 251.8 0.2 1e-74 251.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C P66_CC PF16563.5 EEB08055.1 - 0.13 11.9 0.5 0.28 10.8 0.5 1.5 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 UPF0524 PF15823.5 EEB08056.1 - 0.072 12.5 4.2 0.1 11.9 3.8 1.4 1 1 0 1 1 1 0 UPF0524 of C3orf70 Med2 PF11214.8 EEB08056.1 - 0.57 10.4 7.1 0.39 10.9 0.4 3.0 2 1 0 2 2 2 0 Mediator complex subunit 2 TFIIA PF03153.13 EEB08056.1 - 2.3 8.1 36.6 3.1 7.7 36.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NTP_transferase PF00483.23 EEB08057.1 - 1.1e-54 185.7 0.0 1.6e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EEB08057.1 - 7.5e-12 44.5 5.0 3.1e-10 39.3 2.3 3.4 2 1 1 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEB08057.1 - 1.9e-11 44.6 0.0 3.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EEB08057.1 - 0.00028 20.6 1.1 0.00028 20.6 1.1 2.8 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EEB08057.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 EEB08057.1 - 0.04 12.0 0.4 0.064 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EEB08057.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase CUE PF02845.16 EEB08058.1 - 1.6e-06 27.6 0.1 4.4e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 CUE domain TipAS PF07739.13 EEB08058.1 - 0.12 12.9 0.3 1.4 9.5 0.3 2.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain zf-CCCH_4 PF18044.1 EEB08059.1 - 6.1e-14 51.4 10.5 5.4e-07 29.3 1.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EEB08059.1 - 5.1e-11 42.2 11.5 2e-05 24.4 2.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEB08059.1 - 4.8e-10 39.2 18.5 1.3e-05 25.0 4.6 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EEB08059.1 - 2.5e-08 34.6 5.7 2.7e-05 24.8 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EEB08059.1 - 0.002 18.3 5.3 0.3 11.3 6.6 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEB08059.1 - 0.016 15.6 15.8 0.55 10.8 2.8 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf_CCCH_5 PF18384.1 EEB08059.1 - 1.8 8.8 6.4 3.9 7.7 1.5 2.4 1 1 1 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) Ribosomal_L22 PF00237.19 EEB08060.1 - 1.8e-22 79.5 0.1 2.8e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e AAA_12 PF13087.6 EEB08061.2 - 1.4e-41 142.3 0.0 3.4e-41 141.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEB08061.2 - 2e-26 93.3 4.3 4.1e-26 92.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEB08061.2 - 5.4e-11 43.0 0.4 3.9e-08 33.7 0.1 3.3 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EEB08061.2 - 1.4e-09 38.0 0.0 1.4e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EEB08061.2 - 6.2e-06 25.9 0.8 6.2e-06 25.9 0.8 3.2 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EEB08061.2 - 0.00021 20.8 0.0 0.00047 19.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 EEB08061.2 - 0.00024 21.1 0.0 0.0011 19.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EEB08061.2 - 0.00031 20.6 1.9 0.026 14.3 0.1 3.3 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase SF3A3 PF16837.5 EEB08061.2 - 0.0032 17.9 0.2 2.7 8.6 0.1 2.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF2075 PF09848.9 EEB08061.2 - 0.0058 15.9 0.0 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EEB08061.2 - 0.017 14.9 0.2 0.042 13.6 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 EEB08061.2 - 0.025 15.0 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEB08061.2 - 0.03 14.6 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EEB08061.2 - 0.042 14.3 1.1 0.26 11.7 1.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EEB08061.2 - 0.087 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EEB08061.2 - 0.11 12.1 0.0 0.46 10.0 0.0 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EEB08061.2 - 0.12 11.9 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATP11 PF06644.11 EEB08062.1 - 2.3 7.9 12.4 0.039 13.7 4.7 1.9 2 1 0 2 2 2 0 ATP11 protein MRP-S27 PF10037.9 EEB08062.1 - 8.9 5.1 12.1 19 4.0 12.2 1.7 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 ADH_N PF08240.12 EEB08063.2 - 2e-32 111.3 0.6 5.7e-32 109.8 0.6 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB08063.2 - 1.4e-22 80.0 0.1 2.4e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB08063.2 - 2.6e-05 25.3 0.0 4.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEB08063.2 - 0.025 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Ribosomal_L14 PF00238.19 EEB08064.1 - 3.6e-36 123.9 0.0 4.4e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short PF00106.25 EEB08065.1 - 3.2e-39 134.4 0.1 4.1e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB08065.1 - 1.3e-32 113.2 0.3 1.8e-32 112.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB08065.1 - 1.8e-10 41.0 2.3 4.3e-10 39.8 1.3 2.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EEB08065.1 - 5.9e-06 25.9 0.0 8.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEB08065.1 - 0.001 18.3 0.1 0.0015 17.7 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EEB08065.1 - 0.041 13.8 0.3 0.27 11.1 0.0 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EEB08065.1 - 0.046 14.0 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EEB08065.1 - 0.056 12.8 0.1 0.2 11.0 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cyto_heme_lyase PF01265.17 EEB08067.1 - 5.4e-42 144.4 4.4 1.3e-40 139.8 4.4 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ndc1_Nup PF09531.10 EEB08068.1 - 1.8e-108 363.9 17.6 2e-108 363.7 17.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Herpes_LMP1 PF05297.11 EEB08070.2 - 0.98 8.6 6.8 1.4 8.1 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Lung_7-TM_R PF06814.13 EEB08071.1 - 4.2e-10 39.4 1.0 4.2e-10 39.4 1.0 1.5 2 0 0 2 2 2 1 Lung seven transmembrane receptor PLA2_B PF01735.18 EEB08072.1 - 1.1e-176 588.1 3.9 1.2e-176 587.9 3.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EEB08072.1 - 0.076 13.3 1.6 0.14 12.4 1.6 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ERCC3_RAD25_C PF16203.5 EEB08073.1 - 3.4e-124 412.9 0.9 3.4e-124 412.9 0.9 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EEB08073.1 - 1.2e-38 132.2 0.0 3.4e-38 130.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08073.1 - 1.3e-16 61.1 0.0 3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB08073.1 - 4e-12 46.5 0.1 1.1e-11 45.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EEB08073.1 - 5.5e-09 35.2 0.0 1.5e-08 33.8 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 EEB08073.1 - 7.9e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SIN1 PF05422.12 EEB08073.1 - 0.00024 21.7 2.0 0.0053 17.3 0.7 2.8 2 0 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) Pkinase PF00069.25 EEB08076.1 - 8.8e-72 241.6 0.0 1.4e-71 240.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08076.1 - 2.1e-31 109.1 0.0 3.6e-23 82.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB08076.1 - 4e-06 26.3 0.4 0.0011 18.3 0.0 3.0 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB08076.1 - 0.0034 16.2 0.0 0.0034 16.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEB08076.1 - 0.0066 16.4 0.0 0.76 9.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEB08076.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydin_ADK PF17213.3 EEB08076.1 - 6.3 7.0 5.9 13 6.0 5.9 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain LRR_9 PF14580.6 EEB08077.1 - 1.2e-49 168.2 0.5 1.9e-49 167.5 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EEB08077.1 - 5.6e-08 33.0 9.0 3.4e-05 24.1 1.2 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEB08077.1 - 0.00048 19.8 1.6 0.0029 17.3 1.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat GA PF01468.17 EEB08077.1 - 0.023 14.9 0.2 0.023 14.9 0.2 2.1 2 0 0 2 2 2 0 GA module Skp1_POZ PF03931.15 EEB08078.2 - 9.3e-12 45.0 0.1 1.3e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0300 PF08594.10 EEB08079.2 - 1.2e-79 266.5 0.6 1.7e-79 266.1 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) AMPKBI PF04739.15 EEB08079.2 - 0.029 14.7 2.3 2.5 8.5 0.6 2.6 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain Indigoidine_A PF04227.12 EEB08080.1 - 2.3e-127 424.3 0.6 3.4e-127 423.8 0.6 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EEB08080.1 - 1.5e-26 93.5 0.7 1.3e-16 60.8 0.1 3.1 3 0 0 3 3 3 2 pfkB family carbohydrate kinase RRM_1 PF00076.22 EEB08081.1 - 6.4e-49 163.7 0.1 3.6e-13 49.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB08081.1 - 8.3e-28 96.1 0.0 1e-23 83.0 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif Lsm_interact PF05391.11 EEB08081.1 - 8.6e-07 28.2 4.0 3.1e-06 26.5 4.0 2.0 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM PF05172.13 EEB08081.1 - 0.00016 21.5 0.0 0.035 14.1 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EEB08081.1 - 0.03 14.4 0.1 6.7 6.9 0.0 4.0 4 0 0 4 4 4 0 RNA recognition motif RNA_bind PF08675.11 EEB08081.1 - 0.065 13.3 0.0 2.9 8.0 0.0 3.5 4 1 0 4 4 4 0 RNA binding domain Mak10 PF04112.13 EEB08082.2 - 5.7e-41 139.8 0.7 1.1e-40 138.9 0.7 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Abp2 PF09441.10 EEB08083.2 - 2e-52 177.7 0.0 3.4e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 F-box-like PF12937.7 EEB08085.1 - 4.4e-08 32.9 0.4 1.7e-07 31.0 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEB08085.1 - 4.8e-06 26.3 2.9 6.5e-06 25.9 0.2 2.6 2 0 0 2 2 2 1 F-box domain Skp1 PF01466.19 EEB08086.1 - 4.2e-29 100.4 1.6 2.9e-27 94.5 0.2 2.3 2 0 0 2 2 2 2 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EEB08086.1 - 3.6e-26 91.1 0.8 1.4e-25 89.2 0.6 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF2090 PF09863.9 EEB08086.1 - 0.031 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) BTB PF00651.31 EEB08086.1 - 0.066 13.4 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain Mis12 PF05859.12 EEB08087.1 - 3e-31 108.2 3.4 4.9e-31 107.6 2.9 1.8 1 1 0 1 1 1 1 Mis12 protein Macoilin PF09726.9 EEB08087.1 - 0.0022 16.6 0.8 0.0024 16.5 0.8 1.1 1 0 0 1 1 1 1 Macoilin family Nup54 PF13874.6 EEB08087.1 - 0.0031 17.6 3.9 0.0047 17.0 3.9 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 ATG16 PF08614.11 EEB08087.1 - 0.023 14.9 5.0 0.038 14.2 5.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2457 PF10446.9 EEB08087.1 - 0.027 13.6 0.3 0.038 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prominin PF05478.11 EEB08087.1 - 0.06 11.3 1.2 0.087 10.8 1.2 1.1 1 0 0 1 1 1 0 Prominin Vsr PF03852.15 EEB08087.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr FTA4 PF13093.6 EEB08087.1 - 0.14 12.0 6.1 0.56 10.1 5.0 2.3 1 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MerR-DNA-bind PF09278.11 EEB08087.1 - 1.2 9.7 10.1 1.4 9.6 6.7 2.5 2 1 1 3 3 3 0 MerR, DNA binding DivIC PF04977.15 EEB08087.1 - 4.8 7.0 9.6 2.2 8.1 5.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 EEB08087.1 - 8.3 6.5 7.3 11 6.1 4.4 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 EEB08088.2 - 5.6e-27 93.6 0.8 6.8e-27 93.4 0.8 1.0 1 0 0 1 1 1 1 Swi5 DUF3585 PF12130.8 EEB08088.2 - 0.0031 17.7 2.4 0.0035 17.5 2.4 1.1 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain TPR_MLP1_2 PF07926.12 EEB08088.2 - 0.0076 16.3 2.5 0.0098 16.0 2.5 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.9 EEB08088.2 - 0.0079 16.2 3.0 0.008 16.1 3.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Prefoldin_2 PF01920.20 EEB08088.2 - 0.027 14.4 6.0 0.027 14.4 4.7 1.6 2 0 0 2 2 2 0 Prefoldin subunit TipAS PF07739.13 EEB08088.2 - 0.042 14.4 0.2 0.043 14.4 0.2 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF3584 PF12128.8 EEB08088.2 - 0.055 11.0 2.6 0.058 10.9 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4600 PF15372.6 EEB08088.2 - 0.21 12.0 5.4 0.29 11.6 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) bZIP_2 PF07716.15 EEB08088.2 - 0.22 11.6 7.1 0.47 10.6 7.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Fmp27_WPPW PF10359.9 EEB08088.2 - 0.7 8.7 3.2 0.74 8.6 3.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NifU PF01106.17 EEB08089.1 - 2.3e-26 91.7 0.0 3.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EEB08089.1 - 0.034 14.2 1.1 0.061 13.4 1.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Methyltransf_7 PF03492.15 EEB08089.1 - 0.08 12.1 0.7 0.094 11.9 0.7 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase IF4E PF01652.18 EEB08090.1 - 8.8e-52 175.1 0.2 1.1e-51 174.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mur_ligase_M PF08245.12 EEB08091.1 - 1.3e-06 28.6 0.5 0.0016 18.5 0.1 3.0 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 EEB08091.1 - 0.02 15.1 0.0 0.082 13.2 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain LigB PF02900.18 EEB08092.2 - 1.7e-40 138.8 0.0 2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Lactamase_B_6 PF16661.5 EEB08093.1 - 9.2e-58 194.9 0.3 2.1e-57 193.7 0.3 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EEB08093.1 - 1.3e-33 116.6 3.3 7.2e-32 110.9 0.1 3.3 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EEB08093.1 - 9.6e-17 61.3 0.0 2.3e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EEB08093.1 - 5.3e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EEB08093.1 - 0.00021 20.9 0.1 0.00048 19.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB08093.1 - 0.0018 18.3 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EEB08093.1 - 0.0028 17.6 0.6 0.0074 16.2 0.6 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Transglut_core PF01841.19 EEB08094.1 - 5.1e-13 49.5 1.4 1.1e-12 48.4 1.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EEB08094.1 - 5.8e-11 42.3 0.1 1.1e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain SET PF00856.28 EEB08095.1 - 4.7e-09 36.9 0.0 9.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 SET domain ORC3_N PF07034.11 EEB08095.1 - 0.11 11.5 0.2 0.18 10.8 0.2 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Drf_GBD PF06371.13 EEB08096.2 - 5.4e-19 68.5 2.3 8.6e-19 67.8 2.3 1.3 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF3437 PF11919.8 EEB08096.2 - 0.16 11.9 0.6 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) ING PF12998.7 EEB08097.1 - 5.7e-11 42.9 0.5 8.9e-11 42.3 0.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEB08097.1 - 9.6e-05 22.2 7.5 0.00017 21.4 7.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EEB08097.1 - 0.00092 19.4 0.3 0.002 18.3 0.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Fmp27_WPPW PF10359.9 EEB08097.1 - 0.017 14.0 0.7 0.083 11.7 0.1 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FliT PF05400.13 EEB08097.1 - 0.022 15.6 0.1 0.049 14.5 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliT DUF948 PF06103.11 EEB08097.1 - 0.029 14.6 0.5 0.046 14.0 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EEB08097.1 - 0.071 13.3 0.5 0.14 12.4 0.2 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PHD_2 PF13831.6 EEB08097.1 - 0.075 12.6 2.7 0.17 11.5 2.7 1.6 1 0 0 1 1 1 0 PHD-finger PMC2NT PF08066.12 EEB08097.1 - 0.18 12.5 0.9 0.34 11.6 0.9 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF1664 PF07889.12 EEB08097.1 - 0.22 11.6 0.4 0.34 10.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YojJ PF10372.9 EEB08097.1 - 0.25 11.4 1.3 0.46 10.6 0.0 2.0 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus HMA PF00403.26 EEB08098.1 - 7.5e-10 39.1 0.2 8.8e-10 38.9 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2100 PF09873.9 EEB08098.1 - 0.06 13.2 0.0 0.061 13.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) RRF PF01765.19 EEB08099.2 - 1.6e-26 93.2 14.7 8.1e-26 90.9 11.8 2.0 1 1 1 2 2 2 1 Ribosome recycling factor RasGAP_C PF03836.15 EEB08099.2 - 1.1 9.4 12.4 3.4 7.8 4.4 2.9 1 1 2 3 3 3 0 RasGAP C-terminus BRX_N PF13713.6 EEB08099.2 - 2.3 8.0 5.4 0.82 9.5 1.0 2.7 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain DUF1053 PF06327.14 EEB08099.2 - 3.8 8.1 6.9 0.36 11.4 1.6 2.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) CPSF_A PF03178.15 EEB08100.1 - 6.1e-90 301.8 0.0 2.6e-89 299.7 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 EEB08100.1 - 9.3e-42 143.3 0.0 1.4e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RNase_P_Rpp14 PF01900.19 EEB08101.2 - 0.0011 19.2 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Phage_gp49_66 PF13876.6 EEB08101.2 - 0.084 13.2 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family adh_short PF00106.25 EEB08102.1 - 2.7e-09 36.8 0.0 6.4e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEB08102.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EEB08102.1 - 0.00018 21.1 0.0 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HAD_SAK_1 PF10307.9 EEB08102.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Dus PF01207.17 EEB08103.1 - 3.1e-47 161.2 0.1 8.3e-47 159.8 0.1 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 EEB08103.1 - 0.0024 17.2 0.0 0.015 14.6 0.0 2.2 1 1 1 2 2 2 1 Thiamine monophosphate synthase SpoU_sub_bind PF08032.12 EEB08103.1 - 0.22 11.8 0.5 1.9 8.8 0.1 2.9 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding HSP70 PF00012.20 EEB08104.1 - 3.6e-234 778.5 10.7 4e-234 778.3 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB08104.1 - 8.9e-18 64.2 1.5 8.2e-17 61.0 0.6 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EEB08104.1 - 0.00029 20.2 0.3 0.00084 18.7 0.3 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.11 EEB08104.1 - 0.011 15.0 0.7 0.032 13.5 0.0 2.1 2 0 0 2 2 2 0 StbA protein Zincin_2 PF10103.9 EEB08104.1 - 0.031 13.6 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase RPA PF10134.9 EEB08104.1 - 0.034 13.6 0.4 0.093 12.2 0.4 1.7 1 0 0 1 1 1 0 Replication initiator protein A FGGY_C PF02782.16 EEB08104.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EEB08104.1 - 0.051 14.0 7.8 3 8.3 1.7 4.1 2 1 0 2 2 2 0 Cell division protein FtsA IMD PF08397.11 EEB08104.1 - 0.41 10.0 7.2 0.91 8.9 7.2 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain DDR PF08841.10 EEB08104.1 - 0.53 9.2 5.7 0.28 10.1 0.1 2.9 3 1 1 4 4 4 0 Diol dehydratase reactivase ATPase-like domain TRAF_BIRC3_bd PF16673.5 EEB08104.1 - 3.9 7.3 5.6 36 4.2 2.3 3.3 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Pro_isomerase PF00160.21 EEB08105.1 - 1.6e-50 171.4 0.1 1.8e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3844 PF12955.7 EEB08106.2 - 8.5e-28 96.6 6.7 1.5e-27 95.8 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) AnfG_VnfG PF03139.15 EEB08106.2 - 0.017 15.2 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Antibiotic_NAT PF02522.14 EEB08106.2 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase EGF PF00008.27 EEB08106.2 - 7.5 7.0 9.1 13 6.2 9.1 1.4 1 0 0 1 1 1 0 EGF-like domain Dus PF01207.17 EEB08107.2 - 2.1e-38 132.2 0.0 5.8e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EEB08107.2 - 0.0088 15.9 7.5 0.044 13.7 0.2 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EEB08107.2 - 0.011 15.5 0.2 0.011 15.5 0.2 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Lustrin_cystein PF14625.6 EEB08107.2 - 0.03 14.7 2.0 1.7 9.0 1.9 2.5 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain DUF3974 PF13120.6 EEB08107.2 - 0.12 12.5 0.2 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) zf_CCCH_4 PF18345.1 EEB08107.2 - 3 8.0 8.8 0.29 11.2 0.4 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-C2H2 PF00096.26 EEB08108.1 - 9.7e-05 22.6 16.9 0.013 15.9 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEB08108.1 - 0.0028 18.0 12.3 0.072 13.6 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEB08108.1 - 0.0037 18.0 18.6 0.071 14.0 2.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEB08108.1 - 0.0041 17.4 5.6 0.12 12.7 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EEB08108.1 - 0.013 15.6 7.2 0.24 11.5 0.2 2.8 3 0 0 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 EEB08108.1 - 0.11 13.0 4.1 0.27 11.7 1.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.20 EEB08109.1 - 2.1e-161 538.0 0.0 2.5e-161 537.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEB08109.1 - 4.1e-38 130.7 0.0 7.1e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Bap31 PF05529.12 EEB08110.1 - 2.9e-47 159.9 8.5 4.1e-47 159.4 8.5 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF773 PF05600.12 EEB08110.1 - 0.0013 17.5 1.7 0.0015 17.4 1.7 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Taxilin PF09728.9 EEB08110.1 - 0.0042 16.3 2.1 0.0066 15.7 2.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Bap31_Bap29_C PF18035.1 EEB08110.1 - 0.013 15.5 6.2 0.02 14.9 6.2 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spectrin PF00435.21 EEB08110.1 - 0.068 13.7 0.8 0.1 13.1 0.8 1.2 1 0 0 1 1 1 0 Spectrin repeat PHF5 PF03660.14 EEB08111.1 - 1.3e-49 166.7 10.6 1.5e-49 166.5 10.6 1.0 1 0 0 1 1 1 1 PHF5-like protein HTH_AraC PF00165.23 EEB08111.1 - 0.2 11.8 0.0 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family PolC_DP2 PF03833.13 EEB08111.1 - 0.39 8.5 6.1 0.41 8.5 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EEB08111.1 - 2.2 8.4 17.2 29 4.8 17.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon Sec7 PF01369.20 EEB08112.1 - 4.8e-29 101.3 0.8 9.5e-29 100.4 0.8 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EEB08112.1 - 1e-07 32.3 0.4 4.6e-07 30.2 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEB08112.1 - 0.0011 19.5 5.5 0.027 15.0 0.0 3.4 2 1 1 3 3 3 2 PH domain VASt PF16016.5 EEB08113.2 - 1.7e-23 83.8 0.8 3.9e-23 82.6 0.8 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EEB08113.2 - 6.8e-11 42.3 5.1 1.5e-10 41.2 5.1 1.7 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EEB08113.2 - 3e-06 27.7 0.1 9.9e-06 26.0 0.1 2.0 1 0 0 1 1 1 1 PH domain Myotub-related PF06602.14 EEB08114.2 - 1.9e-100 336.2 0.4 2.4e-100 335.9 0.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EEB08114.2 - 0.007 16.4 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EEB08114.2 - 0.0077 16.0 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB08114.2 - 0.011 15.4 0.1 0.024 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF2920 PF11144.8 EEB08114.2 - 0.07 12.3 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) p450 PF00067.22 EEB08115.2 - 8.3e-56 189.7 0.0 1.1e-55 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LPD13 PF18825.1 EEB08115.2 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 13 VHS PF00790.19 EEB08116.1 - 8.8e-37 126.1 1.2 1.6e-36 125.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EEB08116.1 - 3.5e-17 62.3 8.1 6.9e-17 61.4 8.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EEB08116.1 - 5.3e-09 35.4 15.9 0.00022 20.9 4.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EEB08116.1 - 0.0066 16.7 3.8 0.0066 16.7 3.8 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger IBR PF01485.21 EEB08116.1 - 0.052 13.8 3.8 0.12 12.7 3.8 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GAT PF03127.14 EEB08116.1 - 0.11 12.8 0.1 0.34 11.2 0.1 1.9 1 0 0 1 1 1 0 GAT domain DZR PF12773.7 EEB08116.1 - 0.23 11.5 8.0 7.5 6.7 2.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon adh_short PF00106.25 EEB08117.1 - 1.1e-16 60.9 0.0 1.3e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEB08117.1 - 9.6e-10 38.4 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB08117.1 - 4.3e-06 26.7 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEB08117.1 - 0.00045 19.8 0.0 0.0012 18.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEB08117.1 - 0.00071 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EEB08117.1 - 0.0017 17.9 0.0 0.006 16.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEB08117.1 - 0.038 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Brix PF04427.18 EEB08118.1 - 1.1e-31 110.4 0.0 1.7e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain Hva1_TUDOR PF11160.8 EEB08119.1 - 7.9e-11 42.0 2.5 1e-09 38.4 2.5 1.9 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain COXG PF06240.13 EEB08119.1 - 0.005 16.6 0.1 0.0053 16.5 0.1 1.0 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Ribosomal_S14 PF00253.21 EEB08120.1 - 1.8e-15 56.4 0.4 2e-15 56.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PHD PF00628.29 EEB08121.2 - 1e-08 34.9 6.0 1.7e-08 34.2 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEB08121.2 - 0.001 18.6 4.5 0.0017 17.9 4.5 1.4 1 0 0 1 1 1 1 PHD-finger Aa_trans PF01490.18 EEB08122.1 - 4.6e-77 259.5 43.0 5.5e-77 259.2 43.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EEB08122.1 - 5.9e-10 38.7 24.4 5.9e-10 38.7 24.4 1.9 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family AC_N PF16214.5 EEB08122.1 - 0.51 9.4 3.6 1.2 8.2 3.6 1.6 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ORMDL PF04061.14 EEB08122.1 - 1.1 9.1 7.6 63 3.4 6.1 3.2 1 1 0 1 1 1 0 ORMDL family PAP_assoc PF03828.19 EEB08123.1 - 3.5e-17 62.3 0.4 7.4e-17 61.3 0.4 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEB08123.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEB08123.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PDZ_1 PF12812.7 EEB08124.2 - 1.3e-26 92.4 0.0 3.1e-23 81.6 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EEB08124.2 - 5e-15 56.7 0.0 1.2e-14 55.4 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EEB08124.2 - 1.1e-08 35.2 0.1 0.0055 17.0 0.0 3.4 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EEB08124.2 - 5e-08 33.2 0.0 0.015 15.7 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EEB08124.2 - 6.3e-08 32.4 0.0 0.00084 19.1 0.0 3.1 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EEB08124.2 - 0.034 14.1 0.1 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EEB08124.2 - 0.16 10.6 0.2 0.25 10.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 EEB08125.1 - 0.0015 18.0 4.3 0.0025 17.2 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Lipase_chap PF03280.14 EEB08125.1 - 0.022 14.7 6.6 0.051 13.5 6.6 1.7 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein SKA2 PF16740.5 EEB08125.1 - 0.093 12.5 7.3 0.69 9.7 4.5 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Not3 PF04065.15 EEB08125.1 - 0.13 11.7 4.3 0.21 11.0 2.7 2.1 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Atg14 PF10186.9 EEB08125.1 - 0.2 10.7 5.8 0.3 10.1 5.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 EEB08125.1 - 0.31 11.0 7.2 0.36 10.8 5.4 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF5082 PF16888.5 EEB08125.1 - 0.69 10.2 5.9 0.25 11.6 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fmp27_WPPW PF10359.9 EEB08125.1 - 1.5 7.6 8.9 1.1 8.0 5.8 2.2 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain End3 PF12761.7 EEB08125.1 - 3.3 7.8 9.0 1 9.5 4.7 2.3 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 ATP_synt_H PF05493.13 EEB08126.1 - 2e-19 69.8 1.8 2.4e-19 69.5 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H GPDPase_memb PF10110.9 EEB08126.1 - 0.012 14.4 1.0 0.014 14.2 1.0 1.0 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase CbtA PF09490.10 EEB08126.1 - 0.042 13.6 0.6 0.043 13.6 0.6 1.0 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Pox_EPC_I2-L1 PF12575.8 EEB08126.1 - 0.053 13.7 0.2 0.065 13.5 0.2 1.1 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Popeye PF04831.13 EEB08126.1 - 0.069 13.3 1.1 0.078 13.2 1.1 1.1 1 0 0 1 1 1 0 Popeye protein conserved region Peptidase_S24 PF00717.23 EEB08127.1 - 1.2e-07 31.6 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like UN_NPL4 PF11543.8 EEB08127.1 - 0.12 12.9 0.0 2.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Ribosomal_L7Ae PF01248.26 EEB08128.1 - 2.7e-28 97.6 0.7 3.5e-28 97.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DSPc PF00782.20 EEB08129.1 - 3.8e-29 101.2 0.0 5.5e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEB08129.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEB08129.1 - 0.08 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate LMBR1 PF04791.16 EEB08131.2 - 1.2e-64 219.1 25.4 2.1e-64 218.3 25.4 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein ELFV_dehydrog PF00208.21 EEB08132.1 - 9.2e-79 264.6 1.4 1.2e-78 264.2 1.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EEB08132.1 - 8.2e-49 164.8 0.0 1.6e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 EEB08132.1 - 0.036 13.4 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EEB08132.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding V-ATPase_H_N PF03224.14 EEB08133.1 - 0.048 13.0 4.0 0.24 10.7 0.2 3.1 3 0 0 3 3 3 0 V-ATPase subunit H HEPN_SAV_6107 PF18726.1 EEB08133.1 - 0.052 14.1 0.5 0.32 11.5 0.2 2.2 2 0 0 2 2 2 0 SAV_6107-like HEPN HEAT PF02985.22 EEB08133.1 - 1.7 9.1 4.7 8.4 7.0 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat ArfGap PF01412.18 EEB08134.1 - 1.4e-33 115.5 0.2 1.4e-33 115.5 0.2 2.6 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf EMP24_GP25L PF01105.24 EEB08136.1 - 1.5e-40 139.1 3.4 1.8e-40 138.9 3.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 EEB08136.1 - 0.0041 17.6 0.9 0.0063 17.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) DUF3333 PF11812.8 EEB08136.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) IPP-2 PF04979.14 EEB08137.1 - 3e-19 70.1 9.1 4.4e-19 69.5 9.1 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3275 PF11679.8 EEB08137.1 - 8.8 6.3 8.9 12 5.8 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DnaJ_CXXCXGXG PF00684.19 EEB08138.1 - 0.0015 18.8 6.4 0.025 14.9 0.5 2.3 2 0 0 2 2 2 2 DnaJ central domain DUF5351 PF17302.2 EEB08138.1 - 0.0027 17.8 2.2 0.0027 17.8 2.2 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5351) zf-C3HC4_3 PF13920.6 EEB08138.1 - 0.097 12.5 4.5 4.1 7.4 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TP6A_N PF04406.14 EEB08139.2 - 3.4e-19 68.6 0.8 6.3e-19 67.7 0.8 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 EEB08139.2 - 0.032 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) TPR_1 PF00515.28 EEB08140.1 - 1.8e-07 30.6 0.5 0.00051 19.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEB08140.1 - 4.6e-07 29.5 0.3 0.0026 17.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 EEB08140.1 - 1.1e-06 28.4 0.0 4.2e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.31 EEB08140.1 - 0.0011 19.1 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.6 EEB08140.1 - 0.0016 18.7 0.7 0.1 12.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEB08140.1 - 0.0084 15.8 0.0 0.092 12.5 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_MalT PF17874.1 EEB08140.1 - 0.0092 15.4 0.8 0.019 14.4 0.1 1.9 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EEB08140.1 - 0.014 16.1 0.5 1.3 10.1 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08140.1 - 0.034 14.7 0.6 0.9 10.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEB08140.1 - 0.038 14.6 0.3 0.25 12.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MAS20 PF02064.15 EEB08140.1 - 0.067 13.3 0.3 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor GTP_cyclohydroI PF01227.22 EEB08141.1 - 1.8e-77 258.8 0.5 2.2e-77 258.5 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EEB08141.1 - 4.8e-05 23.4 0.1 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein EIF_2_alpha PF07541.12 EEB08141.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit XRN_M PF17846.1 EEB08142.1 - 1.1e-96 324.5 3.7 2e-96 323.6 3.7 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EEB08142.1 - 1.9e-96 322.2 0.0 3.2e-96 321.4 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EEB08142.1 - 1.7e-56 191.0 0.0 3.6e-56 190.0 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EEB08142.1 - 2e-29 101.6 0.0 5.3e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EEB08142.1 - 1.4e-23 82.7 0.0 2.7e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EEB08142.1 - 3.4e-09 36.7 0.3 9.8e-09 35.2 0.3 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF4252 PF14060.6 EEB08142.1 - 0.12 12.3 0.9 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) tRNA-synt_1c PF00749.21 EEB08143.1 - 2.1e-110 368.5 0.0 3.2e-110 367.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EEB08143.1 - 1.7e-35 122.4 0.9 5.5e-35 120.8 0.5 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 EEB08143.1 - 0.0087 16.3 0.1 0.034 14.4 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EEB08143.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 EEB08143.1 - 0.088 12.8 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hid1 PF12722.7 EEB08144.2 - 8e-169 563.4 2.4 9.8e-169 563.1 2.4 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EEB08144.2 - 6.6e-70 236.2 6.3 8e-70 236.0 6.3 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CTK3 PF12243.8 EEB08144.2 - 0.077 13.0 0.2 3.9 7.5 0.1 2.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Voldacs PF03517.13 EEB08145.1 - 1.5e-22 80.2 0.8 2.5e-22 79.5 0.8 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Glyco_hydro_31 PF01055.26 EEB08146.1 - 2.5e-132 442.2 2.7 3.7e-132 441.7 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EEB08146.1 - 8.9e-24 83.6 0.3 3.2e-23 81.8 0.3 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EEB08146.1 - 5.8e-06 26.5 0.0 2.1e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NPCC PF08058.11 EEB08147.1 - 1.3e-13 51.1 0.0 1.4e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore complex component MethyTransf_Reg PF10119.9 EEB08148.1 - 0.22 12.3 1.3 2.9 8.7 0.1 2.9 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain RRM_1 PF00076.22 EEB08149.2 - 3.1e-32 110.2 0.5 1.5e-12 47.1 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB08149.2 - 0.00039 20.5 0.1 0.002 18.2 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 EEB08149.2 - 0.032 14.3 0.0 3 8.0 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif RL PF17797.1 EEB08149.2 - 0.046 13.7 0.2 4 7.5 0.1 3.5 3 1 0 3 3 3 0 RL domain AIP3 PF03915.13 EEB08149.2 - 0.13 11.4 4.8 0.19 10.8 4.8 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Ribosomal_L1 PF00687.21 EEB08150.1 - 1.6e-27 96.6 0.1 1.9e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_trans_4_3 PF12000.8 EEB08150.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 4 group TAFII28 PF04719.14 EEB08151.1 - 2.1e-39 133.5 0.0 3.3e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region JmjC PF02373.22 EEB08152.1 - 1.3e-42 144.9 0.6 3.2e-42 143.5 0.6 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EEB08152.1 - 6.7e-15 54.8 0.5 6.7e-15 54.8 0.5 2.5 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 EEB08152.1 - 8.5e-06 26.1 14.7 8.5e-06 26.1 14.7 2.0 2 0 0 2 2 2 1 C5HC2 zinc finger ARID PF01388.21 EEB08152.1 - 0.00015 22.4 0.0 0.00043 20.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TERB2 PF15101.6 EEB08153.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Acetyltransf_1 PF00583.25 EEB08154.1 - 1e-17 64.4 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB08154.1 - 1.8e-09 37.9 0.0 3.1e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEB08154.1 - 1.1e-07 31.8 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB08154.1 - 2.2e-06 27.5 0.0 4.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EEB08154.1 - 0.00022 21.9 0.0 0.0003 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB08154.1 - 0.12 12.4 0.0 0.56 10.3 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain TBCA PF02970.16 EEB08154.1 - 0.13 12.6 1.8 0.3 11.4 1.8 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A RrnaAD PF00398.20 EEB08155.1 - 2.1e-34 118.8 0.0 2.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pyr_redox_2 PF07992.14 EEB08156.1 - 1.5e-66 224.6 5.3 1.9e-66 224.3 5.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EEB08156.1 - 1.2e-41 141.5 0.1 3.4e-41 139.9 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EEB08156.1 - 1.3e-16 60.9 7.6 1.2e-15 57.8 2.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB08156.1 - 1.4e-11 44.2 4.6 2.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEB08156.1 - 1.2e-09 38.1 6.6 4.5e-09 36.2 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEB08156.1 - 1.4e-08 34.8 4.1 0.00015 21.9 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EEB08156.1 - 1.2e-06 27.9 12.5 2.1e-06 27.1 3.1 3.1 2 2 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EEB08156.1 - 4.8e-06 26.0 0.1 0.003 16.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EEB08156.1 - 2.3e-05 23.8 4.4 0.00066 19.0 0.4 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EEB08156.1 - 2.9e-05 23.4 8.0 3.6e-05 23.0 1.4 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EEB08156.1 - 5.3e-05 22.6 11.3 0.052 12.8 0.9 4.2 3 2 1 5 5 5 2 FAD binding domain HI0933_like PF03486.14 EEB08156.1 - 0.00042 19.1 13.3 0.024 13.3 0.5 3.8 3 1 1 4 4 4 3 HI0933-like protein 3HCDH_N PF02737.18 EEB08156.1 - 0.0015 18.5 0.7 0.0065 16.4 0.7 2.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EEB08156.1 - 0.18 10.8 0.7 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EEB08156.1 - 0.25 10.9 13.5 0.44 10.1 2.8 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase SGT1 PF07093.11 EEB08157.1 - 4.6e-78 263.1 26.6 7.2e-75 252.6 0.2 2.2 1 1 1 2 2 2 2 SGT1 protein DUF1840 PF08895.11 EEB08157.1 - 0.24 11.8 1.2 0.58 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Gaa1 PF04114.14 EEB08158.1 - 2.1e-112 376.7 13.7 7.7e-111 371.5 13.7 2.1 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component VP7 PF00434.18 EEB08158.1 - 0.029 13.5 0.2 0.058 12.5 0.2 1.4 1 0 0 1 1 1 0 Glycoprotein VP7 DUF1761 PF08570.10 EEB08158.1 - 0.045 14.0 0.8 0.045 14.0 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) CPP1-like PF11833.8 EEB08158.1 - 1 9.0 4.6 2.3 7.9 4.6 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aldedh PF00171.22 EEB08159.2 - 5.3e-161 536.2 1.4 6e-161 536.0 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SUN PF03856.13 EEB08160.1 - 3.3e-93 311.7 14.5 4.5e-93 311.2 14.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 EEB08160.1 - 9.5 4.6 10.4 14 4.1 10.4 1.2 1 0 0 1 1 1 0 Macoilin family COX16 PF14138.6 EEB08161.1 - 1.6e-25 89.4 0.1 1.9e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Ribosomal_L11 PF00298.19 EEB08162.1 - 2.2e-27 95.4 0.1 3.1e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EEB08162.1 - 2.8e-25 87.9 0.7 5.4e-25 87.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain NAPRTase PF04095.16 EEB08163.1 - 4.5e-69 232.7 0.4 6e-69 232.3 0.4 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EEB08163.1 - 1.1e-36 126.0 0.2 1.9e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SAP30_Sin3_bdg PF13867.6 EEB08163.1 - 0.15 12.4 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Nup96 PF12110.8 EEB08164.1 - 1.4e-64 218.0 0.0 2.2e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EEB08164.1 - 4.3e-50 169.7 0.0 7.9e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EEB08164.1 - 5.8e-17 62.3 305.2 1.2e-06 29.3 41.1 9.7 2 2 9 11 11 11 8 Nucleoporin FG repeat region TPR_MLP1_2 PF07926.12 EEB08165.1 - 3.8e-10 39.9 13.7 3.8e-10 39.9 13.7 18.3 4 3 14 19 19 18 6 TPR/MLP1/MLP2-like protein SAVED PF18145.1 EEB08165.1 - 2.4 7.9 6.0 1.7 8.4 0.3 3.1 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain GCFC PF07842.12 EEB08166.1 - 9.3e-55 186.2 7.1 9.3e-55 186.2 7.1 2.0 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EEB08166.1 - 3.6e-18 65.2 0.3 6.7e-18 64.3 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEB08166.1 - 7e-10 38.8 0.3 1.8e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EEB08166.1 - 0.0037 17.6 1.1 0.0037 17.6 1.1 1.9 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal THP2 PF09432.10 EEB08166.1 - 0.036 14.1 1.6 0.14 12.2 1.6 2.0 1 0 0 1 1 1 0 Tho complex subunit THP2 Rhomboid PF01694.22 EEB08167.1 - 0.0032 17.5 3.2 0.0062 16.5 3.2 1.6 1 1 0 1 1 1 1 Rhomboid family Sod_Fe_C PF02777.18 EEB08168.2 - 8e-35 119.1 1.5 1.5e-34 118.2 1.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EEB08168.2 - 2e-27 95.4 5.2 3.6e-27 94.6 5.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acyltransferase PF01553.21 EEB08170.1 - 2.7e-13 49.7 0.0 2.9e-12 46.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Aminotran_1_2 PF00155.21 EEB08171.1 - 1.1e-78 265.0 0.0 1.2e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Endosulfine PF04667.17 EEB08172.1 - 6.9e-25 87.0 0.2 1.4e-24 86.1 0.2 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Nucleolin_bd PF16725.5 EEB08172.1 - 0.039 13.6 0.3 0.056 13.1 0.3 1.3 1 0 0 1 1 1 0 Nucleolin binding domain PP2C PF00481.21 EEB08173.1 - 1.6e-41 142.7 0.0 2.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EEB08173.1 - 9.4e-05 22.1 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Glyco_tran_28_C PF04101.16 EEB08174.2 - 8.4e-29 100.7 0.0 9.6e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Aminotran_1_2 PF00155.21 EEB08175.1 - 7.1e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II ACC_central PF08326.12 EEB08176.1 - 3.3e-271 901.7 0.0 4.1e-271 901.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EEB08176.1 - 4.9e-183 609.3 0.0 6.3e-183 608.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EEB08176.1 - 4.9e-52 176.5 0.0 9.5e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EEB08176.1 - 4.3e-28 98.1 0.1 8.6e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEB08176.1 - 1.7e-20 73.1 0.0 1.4e-19 70.1 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EEB08176.1 - 1.3e-16 60.2 0.1 3.3e-16 58.9 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EEB08176.1 - 0.0035 16.9 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEB08176.1 - 0.0043 16.6 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EEB08176.1 - 0.0056 16.7 0.1 0.032 14.3 0.0 2.4 3 0 0 3 3 3 1 ATP-grasp domain GxGYxYP_N PF16216.5 EEB08176.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Fer2_4 PF13510.6 EEB08176.1 - 0.026 14.6 0.1 0.091 12.8 0.1 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ATPgrasp_ST PF14397.6 EEB08176.1 - 0.1 11.8 0.0 2.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp TMEM208_SND2 PF05620.11 EEB08177.1 - 8.4e-47 159.1 0.8 9.5e-47 158.9 0.8 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 G_glu_transpept PF01019.21 EEB08178.1 - 5.5e-169 563.2 0.0 6.2e-169 563.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Acetyltransf_10 PF13673.7 EEB08179.2 - 3.4e-06 27.0 0.1 5.9e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB08179.2 - 0.0055 17.1 0.1 0.01 16.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB08179.2 - 0.0075 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Phage_holin_3_6 PF07332.11 EEB08179.2 - 0.019 15.0 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Acetyltransf_1 PF00583.25 EEB08179.2 - 0.073 13.3 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family YlaH PF14036.6 EEB08179.2 - 0.088 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 YlaH-like protein DUF1752 PF08550.10 EEB08180.1 - 6.5e-12 45.1 4.0 1.9e-11 43.6 4.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 EEB08180.1 - 3.2e-09 36.7 43.5 9e-08 31.9 17.5 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3295) Cpn60_TCP1 PF00118.24 EEB08181.2 - 4.7e-159 530.1 5.5 5.4e-159 529.9 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EEB08181.2 - 0.1 12.7 3.5 0.55 10.4 0.1 3.1 3 0 0 3 3 3 0 Enolase, N-terminal domain Cation_ATPase PF13246.6 EEB08181.2 - 0.14 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Cation transport ATPase (P-type) PCI PF01399.27 EEB08182.2 - 5.4e-22 78.3 3.5 6.9e-22 78.0 0.0 2.9 4 0 0 4 4 4 1 PCI domain RPN5_C PF18098.1 EEB08182.2 - 4.9e-11 42.5 0.2 1.6e-10 40.9 0.2 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CtaG_Cox11 PF04442.14 EEB08183.1 - 4.6e-59 198.8 0.0 8.1e-59 198.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rsm22 PF09243.10 EEB08183.1 - 4.5e-44 150.8 0.0 7.3e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF2517 PF10725.9 EEB08183.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) SIP1 PF04938.12 EEB08184.1 - 1.4e-17 64.2 6.3 1.7e-17 63.8 6.3 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) EF-G-binding_N PF07299.11 EEB08184.1 - 0.15 12.6 1.0 0.53 10.9 0.4 2.2 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Pex2_Pex12 PF04757.14 EEB08185.1 - 6.3e-26 91.4 9.5 7.9e-26 91.0 9.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EEB08185.1 - 2.3e-05 24.2 1.5 5.4e-05 23.0 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB08185.1 - 5.6e-05 22.9 2.9 5.6e-05 22.9 2.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB08185.1 - 0.00037 20.6 7.0 0.00095 19.3 6.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EEB08185.1 - 0.00046 20.0 3.2 0.00046 20.0 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB08185.1 - 0.001 19.3 4.1 0.0028 18.0 4.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEB08185.1 - 0.022 14.8 5.3 0.062 13.3 5.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger U-box PF04564.15 EEB08185.1 - 0.17 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.6 EEB08185.1 - 0.33 10.8 3.6 0.7 9.8 3.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EEB08185.1 - 1.8 8.9 6.8 1.9 8.8 5.0 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain PCI PF01399.27 EEB08186.1 - 6.1e-16 58.8 0.2 6.1e-16 58.8 0.2 2.4 2 1 0 2 2 2 1 PCI domain Spo0A_C PF08769.11 EEB08186.1 - 0.0089 16.1 0.6 0.26 11.4 0.3 2.9 2 1 0 2 2 2 1 Sporulation initiation factor Spo0A C terminal FRB_dom PF08771.11 EEB08186.1 - 0.043 14.2 7.6 4.1 7.9 1.0 3.5 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain GntR PF00392.21 EEB08186.1 - 0.046 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family RPN6_N PF18055.1 EEB08186.1 - 0.047 14.0 4.3 1.5 9.2 0.7 3.4 1 1 3 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain LMBR1 PF04791.16 EEB08186.1 - 6 5.6 8.5 6.2 5.6 4.8 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Ribosomal_L37e PF01907.19 EEB08187.1 - 4.8e-27 93.9 11.0 4.8e-27 93.9 11.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 EEB08187.1 - 0.0094 16.0 1.4 0.014 15.4 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 EEB08187.1 - 0.064 13.3 0.9 0.096 12.7 0.9 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EEB08187.1 - 0.078 13.1 1.8 0.11 12.7 1.8 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 EEB08187.1 - 0.18 11.3 3.1 0.47 9.9 3.1 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DUF2688 PF10892.8 EEB08187.1 - 1.5 8.3 5.8 11 5.6 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) HOOK PF05622.12 EEB08188.2 - 0.0034 15.6 18.7 0.0042 15.3 18.7 1.2 1 0 0 1 1 1 1 HOOK protein HIP1_clath_bdg PF16515.5 EEB08188.2 - 0.012 16.2 3.1 0.012 16.2 3.1 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 EEB08188.2 - 0.014 14.1 14.0 0.02 13.5 14.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4201 PF13870.6 EEB08188.2 - 0.032 14.0 25.1 0.015 15.1 18.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 EEB08188.2 - 0.066 13.4 23.4 0.36 11.0 4.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding L31 PF09784.9 EEB08188.2 - 0.093 13.2 5.9 0.41 11.1 0.4 2.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 FUSC PF04632.12 EEB08188.2 - 0.17 10.4 2.2 0.21 10.1 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 EEB08188.2 - 0.28 10.4 20.7 0.24 10.7 8.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ZapD PF07072.11 EEB08188.2 - 0.49 10.1 8.4 1.1 8.9 7.0 2.2 1 1 0 1 1 1 0 Cell division protein Cbl_N PF02262.16 EEB08188.2 - 0.82 9.7 7.5 1.7 8.7 4.5 2.3 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 USP8_interact PF08941.10 EEB08188.2 - 1.3 8.8 10.1 0.36 10.6 2.9 2.3 2 1 0 2 2 2 0 USP8 interacting MetOD2 PF18548.1 EEB08188.2 - 2.1 8.5 10.5 0.083 13.0 3.0 2.5 2 2 0 2 2 2 0 Metanogen output domain 2 Fez1 PF06818.15 EEB08188.2 - 2.8 8.4 24.1 0.48 10.8 16.6 2.1 1 1 0 2 2 2 0 Fez1 Noelin-1 PF12308.8 EEB08188.2 - 3.5 7.7 9.2 2.4 8.2 3.9 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein zf-C4pol PF14260.6 EEB08188.2 - 5.6 7.5 8.5 29 5.2 1.6 3.2 1 1 2 3 3 3 0 C4-type zinc-finger of DNA polymerase delta CLZ PF16526.5 EEB08188.2 - 6.1 7.3 17.9 4 7.9 1.1 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 EEB08188.2 - 6.5 7.5 21.9 66 4.2 1.3 3.3 1 1 1 2 2 2 0 Initiation control protein YabA CorA PF01544.18 EEB08188.2 - 6.7 5.9 10.3 12 5.1 10.3 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 EEB08188.2 - 6.8 6.8 27.3 13 5.8 18.4 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein tRNA_int_endo PF01974.17 EEB08189.1 - 1e-17 63.9 0.1 2.7e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EEB08189.1 - 0.012 15.3 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain EOS1 PF12326.8 EEB08190.1 - 1.6e-41 142.2 11.8 9.6e-41 139.6 11.8 2.0 1 1 0 1 1 1 1 N-glycosylation protein Lectin_N PF03954.14 EEB08191.1 - 0.0043 16.8 5.7 1.1 9.0 0.0 3.3 3 0 0 3 3 3 2 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 EEB08191.1 - 0.011 16.0 10.7 0.99 9.6 1.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family zf-AD PF07776.15 EEB08191.1 - 0.02 15.1 0.2 0.059 13.6 0.0 2.0 2 0 0 2 2 1 0 Zinc-finger associated domain (zf-AD) WDCP PF15390.6 EEB08191.1 - 0.053 11.9 7.1 0.07 11.5 7.1 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CCDC92 PF14916.6 EEB08191.1 - 0.06 13.1 0.1 0.06 13.1 0.1 2.9 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DivIC PF04977.15 EEB08191.1 - 0.097 12.4 0.2 0.097 12.4 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 EEB08191.1 - 0.13 12.3 16.0 2.4 8.2 1.5 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 EEB08191.1 - 0.19 12.0 0.4 0.19 12.0 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF3573 PF12097.8 EEB08191.1 - 0.23 10.2 2.0 1 8.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Vps51 PF08700.11 EEB08191.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.1 3 0 0 3 3 3 0 Vps51/Vps67 NPV_P10 PF05531.12 EEB08191.1 - 0.3 11.6 1.4 20 5.8 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EEB08191.1 - 0.37 11.2 4.3 4.1 7.9 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YPEB PF14620.6 EEB08191.1 - 0.43 9.9 9.1 2.2 7.6 1.2 2.6 1 1 1 2 2 2 0 YpeB sporulation DUF3245 PF11595.8 EEB08191.1 - 0.49 10.9 6.0 0.17 12.4 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PRKG1_interact PF15898.5 EEB08191.1 - 0.57 11.1 16.5 5.3 8.0 0.8 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Bcr-Abl_Oligo PF09036.10 EEB08191.1 - 0.69 10.0 6.6 4 7.5 0.0 3.3 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain ZapB PF06005.12 EEB08191.1 - 1.2 9.7 12.9 3.9 8.0 0.8 3.2 3 0 0 3 3 3 0 Cell division protein ZapB MbeD_MobD PF04899.12 EEB08191.1 - 1.2 9.3 6.1 0.33 11.1 0.3 2.9 4 0 0 4 4 3 0 MbeD/MobD like NYD-SP28_assoc PF14775.6 EEB08191.1 - 1.5 8.9 5.6 9.3 6.4 0.4 3.2 2 1 0 2 2 2 0 Sperm tail C-terminal domain Med9 PF07544.13 EEB08191.1 - 2.5 8.2 16.6 1.3 9.2 0.4 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FtsJ PF01728.19 EEB08192.1 - 4.3e-23 82.3 0.1 5.9e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EEB08192.1 - 3.2e-05 24.5 0.0 0.00033 21.3 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08192.1 - 0.0012 18.6 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08192.1 - 0.0076 16.1 0.0 0.0091 15.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB08192.1 - 0.0089 16.7 0.2 0.45 11.2 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EEB08192.1 - 0.076 12.7 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) OST3_OST6 PF04756.13 EEB08193.1 - 7e-82 275.1 2.8 8.5e-82 274.8 2.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EEB08193.1 - 8.2e-07 29.0 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3169 PF11368.8 EEB08193.1 - 0.043 13.3 5.6 0.074 12.6 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) CPBP PF02517.16 EEB08193.1 - 8.9 6.8 7.0 27 5.2 7.0 1.8 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease Mito_carr PF00153.27 EEB08194.1 - 1.4e-62 207.6 3.3 4.5e-20 71.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18 PF17135.4 EEB08195.2 - 8.4e-90 299.2 6.9 9.4e-90 299.0 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EEB08195.2 - 7.4e-05 23.4 0.2 7.4e-05 23.4 0.2 2.4 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A tRNA_anti-like PF12869.7 EEB08195.2 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like Pput2613-deam PF14427.6 EEB08195.2 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase DUF4276 PF14103.6 EEB08195.2 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) 6PF2K PF01591.18 EEB08196.1 - 4e-73 245.4 0.0 5.7e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEB08196.1 - 8.9e-33 113.6 0.0 2.4e-24 86.1 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEB08196.1 - 0.0012 19.0 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEB08196.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GBP PF02263.19 EEB08196.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.10 EEB08196.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EEB08196.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain HIG_1_N PF04588.13 EEB08197.2 - 0.00027 21.1 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Antimicrobial_6 PF08036.11 EEB08197.2 - 0.15 12.1 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide RhoGAP PF00620.27 EEB08198.1 - 4.8e-21 75.2 0.0 1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EEB08198.1 - 1.9e-18 67.0 0.0 4.6e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain SAM_2 PF07647.17 EEB08200.2 - 5.7e-14 52.0 0.2 1e-13 51.2 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEB08200.2 - 1.5e-13 50.9 0.7 2.5e-13 50.2 0.7 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EEB08200.2 - 5.9e-09 36.5 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_Ste50p PF09235.10 EEB08200.2 - 0.0008 19.6 0.5 0.0017 18.6 0.5 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EEB08200.2 - 0.021 14.8 0.4 0.053 13.5 0.4 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CCDC53 PF10152.9 EEB08200.2 - 0.28 11.6 4.7 0.45 10.9 4.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Utp8 PF10395.9 EEB08201.1 - 2.6e-139 465.8 0.0 2.9e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Utp8 family Ras PF00071.22 EEB08202.1 - 1.6e-34 118.8 0.4 1.9e-34 118.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB08202.1 - 7.6e-26 90.7 0.0 1.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB08202.1 - 1.4e-08 34.4 0.2 1.6e-08 34.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB08202.1 - 3.4e-06 26.6 0.3 4.2e-06 26.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EEB08202.1 - 0.00023 20.1 0.8 0.069 12.0 0.2 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EEB08202.1 - 0.039 13.1 2.5 0.055 12.6 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EEB08202.1 - 0.057 12.9 1.2 0.15 11.5 0.1 2.0 2 1 1 3 3 3 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EEB08202.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase TIP120 PF08623.10 EEB08203.1 - 3.5e-43 147.3 2.1 3.5e-43 147.3 2.1 4.8 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EEB08203.1 - 1.7e-09 37.1 2.1 0.67 10.4 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EEB08203.1 - 9.2e-07 29.2 0.6 0.0038 17.6 0.1 4.8 5 0 0 5 5 5 1 HEAT repeats DsbG_N PF18257.1 EEB08203.1 - 0.0011 19.0 0.4 0.012 15.7 0.1 2.8 2 0 0 2 2 2 1 Disulfide isomerase DsbG N-terminal FWWh PF14922.6 EEB08203.1 - 0.13 12.2 1.7 0.43 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function HEAT_EZ PF13513.6 EEB08203.1 - 0.31 11.6 1.1 30 5.3 0.1 4.1 3 0 0 3 3 3 0 HEAT-like repeat AAA PF00004.29 EEB08204.2 - 3.4e-98 325.2 0.0 2.2e-48 164.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB08204.2 - 1.3e-25 88.9 7.1 4.9e-13 48.7 0.8 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EEB08204.2 - 4.6e-19 68.4 2.4 7.7e-19 67.7 1.2 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EEB08204.2 - 1.8e-14 54.3 0.0 1.5e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEB08204.2 - 2.6e-14 53.3 0.0 1.2e-05 25.1 0.0 3.7 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEB08204.2 - 8.2e-12 45.5 0.0 1.6e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EEB08204.2 - 4.2e-11 43.0 1.5 3.1e-05 24.0 0.0 4.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB08204.2 - 1.2e-10 42.1 0.9 0.02 15.3 0.0 4.8 4 2 2 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 EEB08204.2 - 9.9e-10 38.8 1.0 0.034 14.4 0.0 5.1 3 2 2 5 5 5 2 AAA domain TIP49 PF06068.13 EEB08204.2 - 4.7e-09 35.9 2.8 0.0015 17.8 0.0 3.2 3 1 1 4 4 4 2 TIP49 P-loop domain CDC48_2 PF02933.17 EEB08204.2 - 5.6e-09 35.7 0.0 1.4e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 EEB08204.2 - 3.9e-08 32.9 1.4 0.0027 17.1 0.1 3.0 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EEB08204.2 - 5.6e-08 33.4 0.0 0.0089 16.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEB08204.2 - 8.5e-08 32.1 0.0 0.004 16.9 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EEB08204.2 - 6e-07 29.5 0.0 0.016 15.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EEB08204.2 - 8.7e-07 29.3 0.0 0.048 14.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EEB08204.2 - 2.2e-06 27.3 0.1 0.014 14.9 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EEB08204.2 - 3.6e-06 27.5 0.1 0.029 14.9 0.0 4.1 4 1 0 4 4 2 1 ABC transporter Parvo_NS1 PF01057.17 EEB08204.2 - 4.4e-06 26.0 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 EEB08204.2 - 4.5e-06 26.2 0.3 0.52 9.6 0.0 3.5 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 EEB08204.2 - 7.3e-06 26.3 0.2 0.1 12.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain Sigma54_activat PF00158.26 EEB08204.2 - 1.7e-05 24.6 0.1 0.5 10.1 0.0 3.6 2 2 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 EEB08204.2 - 2.2e-05 24.3 0.1 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 EEB08204.2 - 2.6e-05 24.0 0.0 0.13 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EEB08204.2 - 4.1e-05 22.9 0.0 0.024 13.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEB08204.2 - 7.6e-05 22.4 3.0 1.1 8.8 0.1 4.1 2 2 1 4 4 4 1 AAA domain AAA_17 PF13207.6 EEB08204.2 - 8.9e-05 22.9 0.4 0.59 10.6 0.0 3.6 4 0 0 4 4 2 1 AAA domain PhoH PF02562.16 EEB08204.2 - 0.00013 21.5 0.2 0.37 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 EEB08204.2 - 0.00015 21.7 0.6 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain ResIII PF04851.15 EEB08204.2 - 0.00015 21.8 0.0 0.077 13.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EEB08204.2 - 0.00016 21.7 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EEB08204.2 - 0.00018 21.4 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_3 PF07726.11 EEB08204.2 - 0.00037 20.4 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEB08204.2 - 0.00072 19.5 0.1 0.5 10.3 0.0 3.0 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.9 EEB08204.2 - 0.0014 18.0 0.0 1.5 8.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EEB08204.2 - 0.0015 18.5 0.5 2.4 8.0 0.0 3.9 4 1 0 4 4 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EEB08204.2 - 0.0017 18.1 0.4 2 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEB08204.2 - 0.0028 17.4 0.0 0.29 10.9 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EEB08204.2 - 0.0036 17.7 0.8 2.8 8.3 0.0 3.3 2 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EEB08204.2 - 0.0036 16.6 0.6 6 6.1 0.0 3.5 3 1 0 4 4 4 0 Zeta toxin IPT PF01745.16 EEB08204.2 - 0.0043 16.5 0.3 2.4 7.5 0.0 2.8 3 0 0 3 3 3 1 Isopentenyl transferase Sigma54_activ_2 PF14532.6 EEB08204.2 - 0.0049 17.0 0.0 4 7.5 0.0 3.0 2 1 1 3 3 3 0 Sigma-54 interaction domain Molydop_binding PF01568.21 EEB08204.2 - 0.0054 16.8 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain NTPase_1 PF03266.15 EEB08204.2 - 0.0071 16.3 0.9 2.6 7.9 0.0 4.3 4 0 0 4 4 4 1 NTPase T2SSE PF00437.20 EEB08204.2 - 0.014 14.5 0.0 0.56 9.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 EEB08204.2 - 0.014 14.6 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 EEB08204.2 - 0.021 14.1 0.3 1.1 8.4 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain eIF-1a PF01176.19 EEB08204.2 - 0.025 14.4 0.6 0.7 9.7 2.0 2.7 2 1 1 3 3 2 0 Translation initiation factor 1A / IF-1 NusA_N PF08529.11 EEB08204.2 - 0.072 13.4 8.0 0.048 14.0 2.4 3.2 3 0 0 3 3 2 0 NusA N-terminal domain Cytidylate_kin PF02224.18 EEB08204.2 - 0.082 12.6 1.6 7.8 6.2 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 EEB08204.2 - 0.084 11.7 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Torsin PF06309.11 EEB08204.2 - 0.15 12.2 0.0 29 4.8 0.0 3.2 3 0 0 3 3 3 0 Torsin AAA_6 PF12774.7 EEB08204.2 - 0.16 10.9 0.0 9 5.2 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Zot PF05707.12 EEB08204.2 - 0.21 11.2 0.2 3.2 7.3 0.0 2.9 3 1 1 4 4 3 0 Zonular occludens toxin (Zot) zf-C2H2 PF00096.26 EEB08205.1 - 0.036 14.5 0.3 0.1 13.1 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB08205.1 - 0.078 13.9 0.6 0.18 12.7 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger SNARE PF05739.19 EEB08206.2 - 6.3e-08 32.5 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 SNARE domain OmpH PF03938.14 EEB08206.2 - 0.015 15.6 9.4 0.015 15.6 9.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4315 PF14193.6 EEB08206.2 - 0.045 13.8 3.6 0.045 13.8 3.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4315) Macoilin PF09726.9 EEB08206.2 - 0.83 8.1 11.5 1 7.9 11.5 1.0 1 0 0 1 1 1 0 Macoilin family XhlA PF10779.9 EEB08206.2 - 0.84 9.9 7.4 14 6.0 3.1 2.8 2 1 0 2 2 2 0 Haemolysin XhlA MscS_porin PF12795.7 EEB08206.2 - 0.88 9.1 17.8 0.77 9.3 6.8 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Cluap1 PF10234.9 EEB08206.2 - 1 8.7 13.7 0.31 10.4 6.2 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 TMPIT PF07851.13 EEB08206.2 - 1.1 8.5 7.6 5.1 6.3 5.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.11 EEB08206.2 - 1.3 9.6 9.2 0.59 10.7 3.6 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RNB PF00773.19 EEB08206.2 - 4.8 6.4 9.1 9.4 5.5 9.1 1.7 1 1 0 1 1 1 0 RNB domain DUF4407 PF14362.6 EEB08206.2 - 4.9 6.4 8.3 9.8 5.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 EEB08206.2 - 5.8 7.0 17.9 0.78 9.8 6.8 2.6 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain MDD_C PF18376.1 EEB08209.2 - 2.9e-68 229.3 0.1 4e-68 228.8 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EEB08209.2 - 8.6e-08 32.3 2.1 1.1e-07 32.0 0.5 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain TPR_2 PF07719.17 EEB08210.2 - 1.3e-31 106.1 10.8 4e-05 23.4 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EEB08210.2 - 2e-31 106.5 6.8 2.8e-07 30.1 0.2 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EEB08210.2 - 1.3e-23 81.1 10.6 2.2e-05 24.3 0.1 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB08210.2 - 2e-23 82.4 20.2 3.3e-21 75.3 0.9 5.6 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EEB08210.2 - 7.2e-22 77.5 10.2 1.4e-09 38.1 0.0 8.2 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08210.2 - 1.2e-16 61.0 3.8 0.0048 17.4 0.0 7.3 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEB08210.2 - 3.2e-13 48.7 6.6 0.063 13.3 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08210.2 - 1.4e-11 44.2 0.6 8.3 7.5 0.2 8.1 4 1 3 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEB08210.2 - 1.5e-10 40.6 0.5 0.01 15.5 0.1 5.5 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 EEB08210.2 - 4.8e-09 36.7 2.7 0.2 12.3 0.1 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 EEB08210.2 - 2.2e-07 30.4 0.8 0.052 12.7 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08210.2 - 4.7e-07 29.5 0.1 7.5 6.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEB08210.2 - 6.5e-07 29.0 5.2 0.0041 16.5 0.2 3.9 4 1 1 5 5 5 2 MalT-like TPR region TPR_6 PF13174.6 EEB08210.2 - 5.9e-06 26.6 3.7 3.5 8.4 0.1 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEB08210.2 - 4.5e-05 23.5 0.6 57 4.4 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 EEB08210.2 - 0.0029 17.7 0.1 0.97 9.5 0.1 2.9 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 EEB08210.2 - 0.0072 16.4 2.8 30 4.8 0.0 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 EEB08210.2 - 0.011 16.4 0.1 7.8 7.3 0.0 4.6 5 0 0 5 5 5 0 Sel1 repeat ANAPC8 PF04049.13 EEB08211.1 - 7.7e-38 129.7 2.3 1e-37 129.3 0.6 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EEB08211.1 - 7.2e-32 107.9 28.0 3.2e-05 23.5 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EEB08211.1 - 8e-31 103.7 20.8 5e-05 23.2 0.0 9.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EEB08211.1 - 5e-27 91.8 34.7 0.00054 19.9 0.1 10.0 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08211.1 - 3.2e-20 71.1 19.3 0.0089 16.8 0.2 9.1 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEB08211.1 - 9.4e-18 64.6 9.5 0.00027 21.5 0.0 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EEB08211.1 - 5.4e-16 58.7 15.4 0.00054 20.2 0.1 6.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEB08211.1 - 4.1e-14 52.0 13.7 7.7e-06 25.5 0.5 6.5 6 1 1 7 7 7 3 TPR repeat TPR_19 PF14559.6 EEB08211.1 - 9.6e-14 51.7 18.6 0.0071 16.8 0.4 7.2 5 2 2 7 7 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB08211.1 - 1.3e-11 44.5 24.3 0.00036 20.7 0.5 6.4 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EEB08211.1 - 6.1e-10 38.8 12.9 0.79 10.2 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEB08211.1 - 8e-09 34.9 19.7 0.022 14.8 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB08211.1 - 2.7e-07 30.6 9.3 1.2 9.4 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08211.1 - 5.3e-07 29.3 14.4 0.68 9.9 0.1 7.9 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB08211.1 - 2.3e-06 27.8 25.1 5.3 7.9 0.1 9.6 9 1 1 10 10 10 2 Tetratricopeptide repeat ChAPs PF09295.10 EEB08211.1 - 2.6e-05 23.4 0.2 0.33 9.9 0.0 3.5 3 2 2 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 EEB08211.1 - 0.00055 19.4 5.1 0.0069 15.8 1.7 3.4 3 1 0 3 3 3 1 MalT-like TPR region TPR_15 PF13429.6 EEB08211.1 - 0.00066 19.0 8.1 0.69 9.1 1.2 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat DUF3856 PF12968.7 EEB08211.1 - 0.0059 16.7 1.4 0.38 10.8 0.1 2.6 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 EEB08211.1 - 0.19 12.1 1.4 7.4 7.0 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 EEB08211.1 - 0.4 11.1 4.8 1 9.8 1.9 3.0 2 1 0 2 2 2 0 Bacterial transcriptional activator domain PPR PF01535.20 EEB08211.1 - 4.6 7.7 6.2 18 5.9 0.2 4.5 4 0 0 4 4 4 0 PPR repeat polyprenyl_synt PF00348.17 EEB08212.1 - 1.1e-92 309.7 0.0 1.4e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ccdc124 PF06244.12 EEB08212.1 - 0.26 11.8 1.6 2.2 8.9 1.6 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 B56 PF01603.20 EEB08213.2 - 2.8e-176 586.5 7.9 3.5e-176 586.2 7.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Macoilin PF09726.9 EEB08213.2 - 0.64 8.5 11.9 1 7.8 11.9 1.4 1 0 0 1 1 1 0 Macoilin family Tau95 PF09734.9 EEB08214.2 - 8.4e-38 130.3 0.1 8.4e-38 130.3 0.1 2.0 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EEB08214.2 - 1.2e-22 80.5 0.4 3.5e-18 66.0 0.1 2.4 1 1 1 2 2 2 2 Tau95 Triple barrel domain GATase_5 PF13507.6 EEB08215.2 - 1.9e-98 328.7 0.0 2.7e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EEB08215.2 - 3e-41 141.2 0.1 2.5e-28 99.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EEB08215.2 - 1.9e-25 89.1 0.0 3.6e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EEB08215.2 - 1.4e-19 70.4 0.0 3.3e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain RdRP PF05183.12 EEB08216.1 - 3e-165 551.2 0.0 4.1e-165 550.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase MlaC PF05494.12 EEB08216.1 - 0.11 12.3 0.5 0.26 11.0 0.5 1.6 1 0 0 1 1 1 0 MlaC protein Exo84_C PF16528.5 EEB08217.1 - 4.8e-23 82.1 5.7 4.8e-23 82.1 5.7 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EEB08217.1 - 5.5e-11 42.4 4.2 5.5e-11 42.4 4.2 3.2 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 EEB08217.1 - 4.2e-06 26.9 4.5 4.2e-06 26.9 4.5 3.1 3 1 1 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Hpt PF01627.23 EEB08217.1 - 0.076 13.3 0.3 0.84 9.9 0.1 2.8 2 0 0 2 2 2 0 Hpt domain DUF1664 PF07889.12 EEB08217.1 - 0.1 12.6 5.7 2.5 8.1 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF1319 PF07028.11 EEB08217.1 - 0.16 12.2 5.2 1 9.6 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) MAS20 PF02064.15 EEB08218.1 - 7.5e-41 139.3 1.8 9e-41 139.0 1.8 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Erythro_esteras PF05139.14 EEB08218.1 - 0.0026 17.6 0.1 0.0028 17.5 0.1 1.1 1 0 0 1 1 1 1 Erythromycin esterase Nucleolin_bd PF16725.5 EEB08218.1 - 0.0081 15.8 2.5 0.052 13.2 0.9 2.3 2 0 0 2 2 2 1 Nucleolin binding domain RusA PF05866.11 EEB08218.1 - 0.0084 16.7 0.3 0.012 16.1 0.3 1.2 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA SQHop_cyclase_C PF13243.6 EEB08219.1 - 9.2e-136 452.1 3.3 2.4e-134 447.4 0.5 2.8 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EEB08219.1 - 4.3e-116 387.1 1.5 6.6e-105 350.4 0.1 4.5 5 0 0 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EEB08219.1 - 4.3e-20 71.1 16.6 6.4e-07 29.0 2.5 7.0 7 1 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EEB08219.1 - 5.2e-05 22.4 0.2 0.96 8.4 0.0 4.4 4 1 2 6 6 6 2 A-macroglobulin TED domain Pec_lyase PF09492.10 EEB08219.1 - 0.093 12.0 0.0 66 2.7 0.0 3.8 3 1 1 4 4 4 0 Pectic acid lyase Rho_GDI PF02115.17 EEB08220.1 - 3.8e-60 203.0 0.0 4.5e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TPK_catalytic PF04263.16 EEB08221.2 - 1.2e-33 115.7 0.0 2e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF4743 PF15916.5 EEB08221.2 - 3.9e-16 59.1 0.0 7.3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) TPK_B1_binding PF04265.14 EEB08221.2 - 1.3e-15 56.9 0.0 2.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUDIX PF00293.28 EEB08221.2 - 5e-10 39.5 0.1 1e-09 38.5 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain ABC_membrane PF00664.23 EEB08222.1 - 8.6e-117 389.6 44.9 4.3e-61 207.0 16.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEB08222.1 - 1.4e-66 223.1 0.0 7e-33 114.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEB08222.1 - 1.2e-13 51.0 0.7 5.8e-05 22.6 0.2 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EEB08222.1 - 7.7e-07 28.3 3.0 0.00055 18.9 0.0 3.7 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EEB08222.1 - 6.1e-06 26.6 0.3 0.075 13.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEB08222.1 - 6.3e-06 26.2 0.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEB08222.1 - 8e-06 25.5 1.9 0.0056 16.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEB08222.1 - 1e-05 26.0 0.2 0.067 13.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EEB08222.1 - 5.4e-05 22.6 0.4 0.51 9.6 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin AAA_15 PF13175.6 EEB08222.1 - 8.4e-05 22.4 0.1 0.07 12.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EEB08222.1 - 0.00016 21.6 0.0 0.4 10.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EEB08222.1 - 0.00084 19.1 0.1 0.64 9.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.6 EEB08222.1 - 0.0013 18.9 2.2 0.7 10.2 0.1 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EEB08222.1 - 0.0055 16.9 0.1 4.6 7.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEB08222.1 - 0.0057 17.2 0.0 0.47 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EEB08222.1 - 0.014 14.6 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 EEB08222.1 - 0.022 15.0 0.1 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EEB08222.1 - 0.053 13.6 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 EEB08222.1 - 0.061 13.2 0.1 8.8 6.2 0.0 2.7 2 1 0 2 2 2 0 Rad17 P-loop domain Colicin_K PF17500.2 EEB08222.1 - 0.067 13.8 4.9 6.5 7.4 0.2 2.7 2 0 0 2 2 2 0 Colicin-K AAA_18 PF13238.6 EEB08222.1 - 0.095 13.2 0.0 27 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EEB08222.1 - 0.098 12.2 2.7 2 8.0 0.7 2.7 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EEB08222.1 - 0.11 12.1 0.3 17 4.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EEB08222.1 - 0.12 11.9 0.3 15 5.1 0.1 2.7 2 1 1 3 3 3 0 P-loop containing dynein motor region YfiO PF13525.6 EEB08222.1 - 0.14 11.9 0.3 7.8 6.2 0.0 2.6 3 0 0 3 3 2 0 Outer membrane lipoprotein AAA_5 PF07728.14 EEB08222.1 - 0.15 12.0 0.2 35 4.4 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EEB08222.1 - 0.17 12.0 0.1 36 4.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ribosomal_L39 PF00832.20 EEB08223.1 - 1.2e-21 76.0 11.4 1.4e-21 75.8 11.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein DUF2205 PF10224.9 EEB08224.1 - 2.1e-10 40.4 1.6 2.3e-10 40.3 1.6 1.1 1 0 0 1 1 1 1 Short coiled-coil protein Goodbye PF17109.5 EEB08224.1 - 0.028 14.9 0.1 0.031 14.7 0.1 1.1 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain DUF4279 PF14106.6 EEB08224.1 - 0.052 13.7 0.1 0.063 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) ASF1_hist_chap PF04729.13 EEB08225.1 - 2e-66 222.7 0.3 2.9e-66 222.1 0.3 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3983 PF13137.6 EEB08225.1 - 0.37 10.6 1.7 0.56 10.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Paf1 PF03985.13 EEB08225.1 - 0.47 9.4 20.5 0.63 9.0 20.5 1.3 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 EEB08225.1 - 1.9 8.4 22.3 2.4 8.1 22.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EEB08225.1 - 2.2 7.6 27.9 2.7 7.3 27.9 1.1 1 0 0 1 1 1 0 SDA1 IFT57 PF10498.9 EEB08225.1 - 4 6.3 17.0 5.4 5.9 17.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BUD22 PF09073.10 EEB08225.1 - 5.6 6.2 23.1 6.4 6.0 23.1 1.1 1 0 0 1 1 1 0 BUD22 AdoMet_MTase PF07757.13 EEB08226.1 - 4.4e-48 162.3 0.0 8e-48 161.4 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EEB08226.1 - 0.0035 17.4 0.1 0.04 13.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08226.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08226.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain COPI_assoc PF08507.10 EEB08227.1 - 1.6e-17 63.8 4.5 2e-17 63.4 4.5 1.0 1 0 0 1 1 1 1 COPI associated protein TetR_C_34 PF17929.1 EEB08227.1 - 0.061 13.4 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 7tm_3 PF00003.22 EEB08227.1 - 0.12 12.1 4.9 0.15 11.8 4.9 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR SNRNP27 PF08648.12 EEB08228.1 - 3e-22 78.4 0.3 6e-22 77.5 0.3 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins ADH_N PF08240.12 EEB08229.2 - 1.4e-34 118.3 0.7 3e-34 117.2 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB08229.2 - 2.4e-21 76.1 0.3 3.5e-21 75.5 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEB08229.2 - 0.0021 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEB08229.2 - 0.0027 18.8 0.0 0.0048 18.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEB08229.2 - 0.0057 16.0 0.3 0.012 14.9 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EEB08229.2 - 0.13 11.7 0.1 0.27 10.6 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Gtr1_RagA PF04670.12 EEB08230.1 - 4.4e-71 238.9 1.7 5.8e-71 238.5 1.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EEB08230.1 - 2.6e-05 23.8 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEB08230.1 - 0.0026 18.0 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEB08230.1 - 0.0031 17.0 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEB08230.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EEB08230.1 - 0.034 14.5 0.0 0.079 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EEB08230.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain F_bP_aldolase PF01116.20 EEB08231.2 - 1.7e-88 296.8 0.0 1.9e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NADH_dhqG_C PF09326.11 EEB08231.2 - 0.11 13.2 0.5 1.9 9.2 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal Septin PF00735.18 EEB08232.1 - 4.3e-88 295.3 0.1 5.7e-88 294.9 0.1 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EEB08232.1 - 2.1e-06 27.4 0.1 0.0011 18.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB08232.1 - 9.7e-06 25.6 2.0 0.0015 18.4 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EEB08232.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EEB08232.1 - 0.0013 19.0 0.1 0.0049 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEB08232.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.16 EEB08232.1 - 0.0039 16.5 0.0 0.0085 15.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.12 EEB08232.1 - 0.0095 15.3 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EEB08232.1 - 0.021 14.6 0.1 0.77 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EEB08232.1 - 0.025 15.0 0.1 0.16 12.4 0.1 2.1 1 1 1 2 2 2 0 RNA helicase Roc PF08477.13 EEB08232.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EEB08232.1 - 0.048 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FOXP-CC PF16159.5 EEB08232.1 - 0.054 14.1 1.6 0.14 12.8 0.8 2.1 1 1 0 1 1 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 EEB08232.1 - 0.062 13.7 0.3 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EEB08232.1 - 0.065 12.5 0.1 0.36 10.0 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain Ras PF00071.22 EEB08232.1 - 0.068 12.8 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Ras family Pox_A32 PF04665.12 EEB08232.1 - 0.069 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Herpes_BLRF2 PF05812.12 EEB08232.1 - 0.069 13.3 0.4 0.68 10.1 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein IstB_IS21 PF01695.17 EEB08232.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SAB PF04382.13 EEB08232.1 - 0.11 12.6 1.1 0.23 11.5 1.1 1.5 1 0 0 1 1 1 0 SAB domain AAA PF00004.29 EEB08232.1 - 0.14 12.6 0.1 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EEB08232.1 - 0.16 12.4 0.1 0.71 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 EEB08232.1 - 0.24 11.4 0.7 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Myc-LZ PF02344.15 EEB08232.1 - 0.59 10.3 7.3 8.3 6.6 0.3 3.0 3 0 0 3 3 3 0 Myc leucine zipper domain G-alpha PF00503.20 EEB08232.1 - 0.95 8.6 5.1 1.3 8.1 0.3 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Casc1_N PF15927.5 EEB08232.1 - 1.5 8.4 13.3 1.5 8.4 11.2 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Exo_endo_phos PF03372.23 EEB08233.2 - 4.3e-06 26.4 0.0 1.9e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EEB08234.1 - 9.6e-69 231.7 0.0 1.5e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08234.1 - 8.5e-48 162.9 0.0 1.4e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB08234.1 - 1.9e-07 30.2 1.0 1.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEB08234.1 - 0.0021 17.4 0.0 0.008 15.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like DUF4660 PF15559.6 EEB08234.1 - 0.055 13.8 0.3 0.1 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Abhydrolase_2 PF02230.16 EEB08235.1 - 1.5e-33 116.5 0.0 1.7e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EEB08235.1 - 0.0016 19.1 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EEB08235.1 - 0.0017 17.7 0.0 0.098 12.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EEB08235.1 - 0.0089 15.3 0.1 0.48 9.6 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EEB08235.1 - 0.066 13.0 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 EEB08235.1 - 0.066 12.1 0.0 2.1 7.2 0.0 2.3 2 1 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EEB08235.1 - 0.073 12.1 0.1 0.15 11.1 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 EEB08235.1 - 0.12 12.1 0.2 0.69 9.5 0.1 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 EEB08235.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family SH3_1 PF00018.28 EEB08237.2 - 1.6e-10 40.4 0.1 2.8e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEB08237.2 - 4.9e-09 35.7 0.1 1.1e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEB08237.2 - 5.2e-05 23.0 0.9 8.8e-05 22.3 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core PF01841.19 EEB08237.2 - 0.00017 22.0 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 EEB08238.1 - 6.3e-35 118.6 24.8 7e-07 29.9 0.6 9.6 11 0 0 11 11 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08238.1 - 2.1e-22 79.2 0.0 1.3e-06 28.6 0.0 6.4 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB08238.1 - 2e-09 37.6 0.6 0.0023 17.8 0.0 4.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EEB08238.1 - 1.1e-08 34.4 1.0 0.49 9.3 0.0 5.1 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEB08238.1 - 7.7e-06 25.4 0.3 0.0011 18.4 0.1 3.0 1 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 EEB08238.1 - 3.7e-05 24.1 0.1 23 5.7 0.0 5.6 5 0 0 5 5 5 0 PQQ-like domain PD40 PF07676.12 EEB08238.1 - 0.00015 21.6 0.2 1.6 8.8 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EEB08238.1 - 0.00033 20.1 0.5 2.6 7.3 0.1 4.1 3 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal BBS2_N PF14781.6 EEB08238.1 - 0.00093 19.1 0.0 4.5 7.2 0.0 3.8 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, N-terminal Nup160 PF11715.8 EEB08238.1 - 0.0016 17.2 2.3 0.0049 15.6 0.3 2.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EEB08238.1 - 0.0029 17.0 0.0 0.032 13.5 0.0 2.5 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus HPS3_N PF14761.6 EEB08238.1 - 0.026 14.1 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 PQQ PF01011.21 EEB08238.1 - 2.8 8.0 6.5 14 5.8 0.2 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat 60KD_IMP PF02096.20 EEB08239.1 - 4.2e-27 95.1 3.4 4.2e-27 95.1 3.4 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein Ribosomal_L7Ae PF01248.26 EEB08240.2 - 4.9e-26 90.3 0.0 5.9e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 EEB08241.1 - 3.5e-64 216.7 0.0 7.2e-64 215.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08241.1 - 5.2e-36 124.2 0.0 9.9e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08241.1 - 8.1e-05 22.1 0.1 0.00035 20.0 0.1 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEB08241.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEB08241.1 - 0.087 11.6 0.0 0.087 11.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Vac_ImportDeg PF09783.9 EEB08242.1 - 2.7e-51 173.6 0.3 3e-51 173.4 0.3 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pkinase PF00069.25 EEB08243.1 - 1.4e-41 142.7 0.0 1.7e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08243.1 - 2.5e-24 86.0 0.0 2.9e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08243.1 - 1.2e-05 24.8 0.1 0.001 18.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Choline_kinase PF01633.20 EEB08243.1 - 0.037 13.6 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase BAH PF01426.18 EEB08244.1 - 8.8e-18 64.3 0.2 3.6e-17 62.3 0.1 2.1 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H_2 PF13832.6 EEB08244.1 - 6.2e-15 55.3 2.8 6.2e-15 55.3 2.8 4.6 4 1 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEB08244.1 - 4.9e-09 36.3 0.6 4.9e-09 36.3 0.6 5.4 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 EEB08244.1 - 1.2e-06 28.3 13.4 1.2e-06 28.3 13.4 6.4 8 0 0 8 8 8 3 PHD-finger PHD_2 PF13831.6 EEB08244.1 - 0.0059 16.1 0.1 0.0059 16.1 0.1 6.0 5 0 0 5 5 5 3 PHD-finger C1_2 PF03107.16 EEB08244.1 - 0.012 15.9 1.9 0.012 15.9 1.9 7.4 8 1 0 8 8 8 0 C1 domain zf-C2H2 PF00096.26 EEB08245.2 - 9.3e-07 29.0 19.3 2.7e-05 24.4 3.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB08245.2 - 2.5e-05 24.7 13.0 0.0072 17.1 3.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEB08245.2 - 0.013 15.9 1.4 0.013 15.9 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 EEB08245.2 - 0.048 12.2 0.4 0.081 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 EEB08245.2 - 0.12 12.0 2.5 0.37 10.5 1.0 2.3 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 EEB08245.2 - 0.56 10.7 3.8 8.9 6.9 0.5 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEB08245.2 - 1.9 8.9 10.7 0.26 11.6 1.7 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 EEB08245.2 - 2.2 8.4 8.4 0.33 11.0 2.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 EEB08245.2 - 5 7.8 6.5 1.5 9.5 0.3 2.8 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats ORC_WH_C PF18137.1 EEB08247.2 - 4.3e-25 88.4 0.0 9.8e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EEB08247.2 - 6.7e-11 41.9 0.3 1.8e-09 37.2 0.1 2.3 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus Peptidase_M16 PF00675.20 EEB08248.1 - 1.7e-14 54.0 0.4 1e-13 51.5 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEB08248.1 - 2.8e-13 50.3 0.0 5.7e-12 46.0 0.0 2.7 3 1 0 3 3 3 1 Peptidase M16 inactive domain HCNGP PF07818.13 EEB08249.1 - 2.2e-22 79.5 0.2 3.6e-22 78.8 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein MDM31_MDM32 PF08118.11 EEB08250.2 - 1.3e-170 568.6 0.3 8.9e-169 562.5 0.3 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M48_N PF16491.5 EEB08251.2 - 2.3e-53 180.8 8.9 2.3e-53 180.8 8.9 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EEB08251.2 - 1e-45 155.9 0.0 1.8e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF1440 PF07274.12 EEB08251.2 - 0.02 15.2 3.7 0.13 12.7 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1440) SprT-like PF10263.9 EEB08251.2 - 0.054 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Raf1_HTH PF18579.1 EEB08251.2 - 0.065 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Phage_holin_3_6 PF07332.11 EEB08251.2 - 0.26 11.4 3.0 0.28 11.2 1.3 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Arginase PF00491.21 EEB08252.1 - 1.2e-65 221.8 0.0 1.4e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1640 PF07798.11 EEB08253.1 - 4.8e-27 95.1 16.6 6.7e-27 94.7 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GCN5L1 PF06320.13 EEB08253.1 - 0.001 19.2 4.6 0.001 19.2 4.6 2.2 1 1 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) ApoLp-III PF07464.11 EEB08253.1 - 0.088 12.9 12.4 0.16 12.1 12.2 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Atypical_Card PF18461.1 EEB08253.1 - 0.22 11.7 1.5 0.48 10.7 0.2 2.1 2 1 1 3 3 3 0 Atypical caspase recruitment domain LPP PF04728.13 EEB08253.1 - 0.27 11.7 3.0 12 6.3 0.2 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FAM76 PF16046.5 EEB08253.1 - 0.37 10.1 9.9 0.49 9.7 9.9 1.2 1 0 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 EEB08253.1 - 2 8.5 10.7 2.5 8.2 7.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EEB08253.1 - 4 7.8 6.9 13 6.2 0.3 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 EEB08253.1 - 6.8 7.0 10.0 10 6.4 2.2 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Aa_trans PF01490.18 EEB08254.1 - 2.1e-89 300.1 39.6 2.6e-89 299.8 39.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 EEB08255.1 - 5.5e-56 190.1 32.4 7e-56 189.8 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB08255.1 - 2.4e-20 72.8 36.4 3.9e-20 72.1 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EEB08255.1 - 8e-15 54.8 1.1 3e-07 29.8 0.0 3.1 3 0 0 3 3 3 3 Solute carrier family 12 Mhr1 PF12829.7 EEB08256.2 - 3.5e-21 75.1 0.1 5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Atg14 PF10186.9 EEB08257.2 - 3.9e-14 52.5 12.9 2.5e-10 40.0 0.2 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4H2 PF10146.9 EEB08257.2 - 0.052 13.9 3.3 0.086 13.1 3.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.6 EEB08257.2 - 0.058 12.7 3.3 0.088 12.2 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Raco_middle PF17651.1 EEB08257.2 - 0.14 11.8 2.2 0.2 11.3 0.4 2.1 1 1 1 2 2 2 0 RACo middle region Exonuc_VII_L PF02601.15 EEB08257.2 - 0.67 9.5 10.1 1 8.9 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EEB08257.2 - 2.7 8.3 14.4 1.5 9.1 10.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein LDB19 PF13002.7 EEB08258.1 - 3.5e-46 157.3 0.0 5.6e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EEB08258.1 - 6.6e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FYVE PF01363.21 EEB08259.1 - 2.8e-16 59.4 8.8 4.4e-16 58.8 8.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger ATP-synt_C PF00137.21 EEB08260.1 - 6.6e-30 103.2 34.6 9.3e-18 64.3 11.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Metallopep PF12044.8 EEB08261.1 - 3.6e-135 450.9 0.0 5e-135 450.4 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 EEB08261.1 - 3.2e-05 23.9 0.3 0.026 14.4 0.0 2.6 1 1 1 2 2 2 2 Jacalin-like lectin domain Peptidase_M10 PF00413.24 EEB08261.1 - 0.023 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 EEB08261.1 - 0.1 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EEB08261.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 PCI PF01399.27 EEB08262.1 - 1.9e-11 44.4 0.0 5e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EEB08262.1 - 1.6e-05 24.4 0.4 3.4e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix IPK PF03770.16 EEB08263.2 - 2.6e-41 141.7 0.0 4.2e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF679 PF05078.12 EEB08263.2 - 0.087 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF679) Ribosomal_L7Ae PF01248.26 EEB08264.1 - 2.5e-27 94.4 0.0 3.1e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EEB08264.1 - 0.0024 17.9 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EEB08264.1 - 0.0043 16.9 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain SRP9-21 PF05486.12 EEB08265.1 - 1.3e-16 60.7 0.2 1.3e-16 60.7 0.2 2.9 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) DUF4211 PF13926.6 EEB08266.1 - 1.2e-30 106.4 2.4 1.2e-30 106.4 2.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CXCL17 PF15211.6 EEB08266.1 - 0.056 14.2 6.6 0.23 12.3 6.6 2.1 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 PilZ PF07238.14 EEB08266.1 - 0.082 13.2 0.1 5 7.5 0.0 2.5 2 0 0 2 2 2 0 PilZ domain ERF PF04404.12 EEB08266.1 - 7.5 6.4 9.1 4.1 7.3 0.1 3.3 3 0 0 3 3 3 0 ERF superfamily Ebp2 PF05890.12 EEB08267.1 - 3.6e-87 292.3 21.7 3.6e-87 292.3 21.7 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Thioredoxin PF00085.20 EEB08268.1 - 5.3e-55 183.8 0.0 8.3e-27 93.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EEB08268.1 - 7.5e-22 78.0 0.0 2.1e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EEB08268.1 - 2.1e-09 37.8 0.9 0.0026 18.2 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EEB08268.1 - 4.7e-09 36.0 0.0 3.2e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EEB08268.1 - 6.1e-08 32.7 0.0 0.0055 16.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EEB08268.1 - 5.3e-07 29.6 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EEB08268.1 - 7.2e-07 29.5 0.0 0.41 11.0 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 EEB08268.1 - 3.9e-05 23.4 0.1 0.29 10.8 0.1 2.2 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 EEB08268.1 - 0.00028 21.1 0.2 3.2 7.9 0.0 3.2 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 EEB08268.1 - 0.0021 18.0 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain TraF PF13728.6 EEB08268.1 - 0.0026 17.6 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein DUF953 PF06110.11 EEB08268.1 - 0.16 11.6 0.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Tom22 PF04281.13 EEB08269.1 - 6.2e-38 129.7 3.7 7e-38 129.5 3.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 MDM10 PF12519.8 EEB08270.2 - 8.7e-66 222.7 5.1 5.8e-42 144.1 0.9 3.0 1 1 2 3 3 3 3 Mitochondrial distribution and morphology protein 10 WD40 PF00400.32 EEB08271.1 - 2e-21 75.9 10.8 6.1e-06 26.9 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08271.1 - 3e-07 30.6 0.1 0.035 14.4 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EEB08271.1 - 0.0011 18.7 0.0 4.1 7.1 0.0 3.2 2 1 1 3 3 3 2 TUP1-like enhancer of split STAG PF08514.11 EEB08272.1 - 8e-30 103.1 1.2 3.3e-29 101.1 1.2 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 EEB08272.1 - 0.00022 21.5 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EEB08272.1 - 0.099 13.0 0.5 1.8 9.1 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat gag-asp_proteas PF13975.6 EEB08274.1 - 9.4e-06 26.1 0.1 2e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EEB08274.1 - 1.3e-05 25.8 0.0 4.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 EEB08274.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.25 EEB08275.1 - 6.6e-69 232.2 0.0 8.2e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08275.1 - 6.7e-29 100.9 0.0 9.2e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB08275.1 - 3.3e-08 32.9 1.4 5.8e-08 32.1 1.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EEB08275.1 - 1.7e-05 24.5 0.1 3.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EEB08275.1 - 0.00042 19.7 0.1 0.00098 18.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEB08275.1 - 0.0034 16.7 0.1 0.0062 15.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB08275.1 - 0.0071 16.3 0.1 0.0071 16.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S9 PF00380.19 EEB08276.1 - 5.7e-32 110.8 0.9 6.4e-32 110.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 EEB08277.1 - 3.2e-78 261.7 3.0 4e-78 261.4 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sod_Fe_N PF00081.22 EEB08277.1 - 0.089 13.3 0.0 0.23 12.0 0.0 1.7 1 1 1 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain 3-HAO PF06052.12 EEB08277.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Ribosomal_S11 PF00411.19 EEB08278.1 - 2e-47 160.1 2.4 2.4e-47 159.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EEB08278.1 - 0.084 13.1 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ribosomal_L30_N PF08079.12 EEB08279.1 - 3.1e-22 78.6 15.0 6.8e-22 77.5 15.0 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EEB08279.1 - 2.7e-19 68.8 1.0 6.3e-19 67.6 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e YebO PF13974.6 EEB08279.1 - 0.19 11.9 2.5 0.42 10.7 2.5 1.6 1 0 0 1 1 1 0 YebO-like protein PPR_2 PF13041.6 EEB08280.1 - 8.2e-24 83.6 0.4 4.4e-19 68.4 0.1 4.0 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EEB08280.1 - 2.1e-07 30.9 1.3 4.9e-05 23.3 0.1 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 EEB08280.1 - 1.8e-06 27.8 0.8 0.0034 17.5 0.0 4.7 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 EEB08280.1 - 0.013 15.2 0.5 0.79 9.5 0.0 3.4 4 0 0 4 4 4 0 PPR repeat Cut8 PF08559.10 EEB08280.1 - 0.27 10.8 7.7 0.18 11.4 0.6 3.0 3 0 0 3 3 3 0 Cut8, nuclear proteasome tether protein Clathrin PF00637.20 EEB08280.1 - 0.29 11.0 4.8 2.3 8.1 0.1 3.0 2 1 1 3 3 3 0 Region in Clathrin and VPS DUF572 PF04502.13 EEB08281.2 - 8.5e-41 140.7 10.9 1.2e-40 140.2 10.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-CHY PF05495.12 EEB08282.2 - 3.6e-09 37.0 15.1 3.6e-09 37.0 15.1 3.9 2 1 0 2 2 2 1 CHY zinc finger UCH PF00443.29 EEB08283.2 - 2.2e-57 194.5 0.2 2.2e-57 194.5 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB08283.2 - 2.2e-17 63.6 1.1 5.9e-17 62.2 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 EEB08283.2 - 0.0095 15.7 0.4 0.028 14.2 0.4 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger USP8_dimer PF08969.11 EEB08283.2 - 0.04 14.1 0.7 0.1 12.8 0.7 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain zf-U1 PF06220.12 EEB08284.1 - 1.1e-12 47.5 1.0 2.2e-12 46.5 1.0 1.6 1 0 0 1 1 1 1 U1 zinc finger Membralin PF09746.9 EEB08284.1 - 3.8 6.4 5.0 4.7 6.2 5.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein WD40 PF00400.32 EEB08285.1 - 9e-09 35.8 3.3 0.0013 19.5 0.0 5.0 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08285.1 - 8.3e-08 32.4 0.0 0.1 12.9 0.0 3.3 1 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEB08285.1 - 0.0081 15.8 0.0 0.53 9.8 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain WDCP PF15390.6 EEB08285.1 - 0.13 10.6 0.0 0.23 9.8 0.0 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family WD40 PF00400.32 EEB08286.1 - 2.1e-13 50.5 7.1 9.3e-05 23.1 0.2 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08286.1 - 5.9e-07 29.7 0.2 0.033 14.5 0.0 4.3 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EEB08287.2 - 8.5e-12 44.7 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP_sp32 PF07222.12 EEB08287.2 - 0.012 15.1 2.8 0.018 14.5 2.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Aminotran_3 PF00202.21 EEB08288.1 - 3e-106 355.5 0.0 3.4e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1770 PF08589.10 EEB08289.1 - 1.6e-09 38.6 1.5 2.2e-09 38.2 1.5 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SMC_N PF02463.19 EEB08290.2 - 3.6e-26 92.0 0.0 6.7e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEB08290.2 - 1.7e-15 58.1 20.8 1.7e-15 58.1 20.8 6.1 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.6 EEB08290.2 - 4.4e-05 23.4 16.7 4.4e-05 23.4 16.7 3.7 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EEB08290.2 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPV_P10 PF05531.12 EEB08290.2 - 0.00076 19.9 23.5 0.37 11.3 0.2 6.2 4 2 2 6 6 6 2 Nucleopolyhedrovirus P10 protein AAA_21 PF13304.6 EEB08290.2 - 0.0031 17.4 0.3 0.0031 17.4 0.3 3.6 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EEB08290.2 - 0.012 16.0 0.4 0.1 13.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEB08290.2 - 0.039 13.9 0.9 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EEB08290.2 - 0.092 12.3 0.0 0.092 12.3 0.0 5.0 4 2 0 5 5 5 0 AAA domain Spc7 PF08317.11 EEB08290.2 - 0.17 10.7 81.0 0.012 14.5 13.8 5.4 2 2 3 5 5 5 0 Spc7 kinetochore protein MecA_N PF05223.11 EEB08290.2 - 0.2 11.9 5.6 0.72 10.1 5.6 2.0 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain AAA_25 PF13481.6 EEB08290.2 - 0.23 11.0 1.7 4.1 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain TetR_C_13 PF16925.5 EEB08290.2 - 2.2 8.3 5.6 4.3 7.3 0.1 3.6 2 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DASH_Dad3 PF08656.10 EEB08291.1 - 2.2e-24 85.3 2.5 2.5e-24 85.1 2.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 K-box PF01486.17 EEB08291.1 - 0.011 15.9 1.3 0.018 15.2 1.3 1.3 1 0 0 1 1 1 0 K-box region Flagellar_rod PF05149.12 EEB08291.1 - 0.027 14.0 0.2 0.033 13.7 0.2 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Ribosomal_S7e PF01251.18 EEB08291.1 - 0.047 13.5 0.4 0.065 13.0 0.2 1.3 1 1 0 1 1 1 0 Ribosomal protein S7e HTH_6 PF01418.17 EEB08291.1 - 0.11 12.5 1.0 0.14 12.2 0.3 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Pkinase PF00069.25 EEB08292.1 - 1.8e-63 214.4 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08292.1 - 7.6e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEB08292.1 - 1.5e-14 54.0 1.1 8.1e-14 51.7 0.4 2.4 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EEB08292.1 - 4.1e-08 32.9 0.0 1.4e-07 31.1 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB08292.1 - 2.2e-05 23.4 0.0 3.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EEB08292.1 - 4.8e-05 22.5 1.7 0.00014 21.0 1.7 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEB08292.1 - 0.0014 18.0 0.3 0.0027 17.1 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 EEB08292.1 - 0.041 14.1 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 FHA domain Yop-YscD_cpl PF16697.5 EEB08292.1 - 0.13 12.6 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Pex16 PF08610.10 EEB08294.1 - 2.2e-60 204.6 2.1 2.4e-60 204.4 2.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SWIRM PF04433.17 EEB08295.2 - 8.1e-12 45.3 0.1 2.7e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain VTC PF09359.10 EEB08296.1 - 1e-76 258.0 2.3 1.1e-76 257.9 0.1 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EEB08296.1 - 3.7e-12 46.5 2.9 7.5e-12 45.5 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EEB08296.1 - 3.4e-09 37.1 13.0 0.0095 15.9 1.0 4.2 2 1 2 4 4 4 3 SPX domain NMN_transporter PF04973.12 EEB08296.1 - 0.059 13.3 1.3 0.095 12.7 1.3 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter FliD_C PF07195.12 EEB08296.1 - 0.14 11.5 0.3 0.28 10.6 0.3 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Importin_rep_6 PF18829.1 EEB08296.1 - 0.4 10.8 2.9 0.85 9.8 2.9 1.5 1 0 0 1 1 1 0 Importin repeat 6 NUDIX PF00293.28 EEB08297.1 - 2.2e-10 40.7 0.0 4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_71 PF03659.14 EEB08298.1 - 5e-124 413.9 10.7 5.6e-124 413.8 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DASH_Duo1 PF08651.10 EEB08299.1 - 0.022 14.5 0.6 0.16 11.8 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 Nexin_C PF08628.12 EEB08300.2 - 1e-09 39.0 0.1 9.9e-09 35.8 0.1 2.3 1 1 0 1 1 1 1 Sorting nexin C terminal MFS_1 PF07690.16 EEB08301.1 - 2.5e-20 72.7 28.8 1.1e-19 70.7 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EEB08301.1 - 7e-08 31.3 0.6 7e-08 31.3 0.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Nab2 PF11517.8 EEB08302.2 - 0.0044 17.3 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 EEB08302.2 - 0.012 16.0 7.8 0.039 14.4 1.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DltD PF04914.12 EEB08302.2 - 0.015 14.7 1.3 0.019 14.4 0.9 1.3 1 1 0 1 1 1 0 DltD protein NAD_binding_2 PF03446.15 EEB08302.2 - 0.056 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase EnY2 PF10163.9 EEB08302.2 - 0.088 13.2 0.9 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 Transcription factor e(y)2 MSC PF09402.10 EEB08303.1 - 1.6e-61 208.6 0.1 2.4e-61 208.1 0.1 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EEB08303.1 - 5.4e-16 58.0 0.7 1.8e-15 56.3 0.1 2.2 2 0 0 2 2 2 1 HeH/LEM domain ThiJ_like PF17124.5 EEB08304.1 - 5.4e-66 222.0 0.0 6.8e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EEB08304.1 - 0.038 13.8 0.0 0.081 12.7 0.0 1.5 1 1 0 1 1 1 0 DJ-1/PfpI family ORC5_C PF14630.6 EEB08305.1 - 1.3e-65 221.8 0.1 1.8e-65 221.3 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EEB08305.1 - 4.4e-10 40.2 0.0 3e-09 37.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EEB08305.1 - 0.052 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 EEB08306.1 - 4.8e-61 202.7 7.4 1.6e-21 76.0 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB08306.1 - 0.0076 15.4 0.0 2.9 7.0 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Ras PF00071.22 EEB08307.1 - 3.9e-60 202.1 0.1 4.6e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB08307.1 - 4.5e-22 78.5 0.0 6.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB08307.1 - 2.5e-09 36.8 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB08307.1 - 9.1e-07 28.6 0.1 1.2e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEB08307.1 - 5.6e-05 23.2 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEB08307.1 - 0.0001 22.3 0.0 0.22 11.4 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase DUF2075 PF09848.9 EEB08307.1 - 0.012 14.9 0.1 1.8 7.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) FeoB_N PF02421.18 EEB08307.1 - 0.022 14.3 0.0 0.074 12.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EEB08307.1 - 0.029 14.2 0.5 0.39 10.5 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EEB08307.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 EEB08307.1 - 0.14 12.5 0.1 0.26 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMS1_N PF10433.9 EEB08308.1 - 5.9e-67 226.4 1.0 5.9e-67 226.4 1.0 2.0 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEB08308.1 - 4.5e-47 160.9 0.0 1.1e-45 156.4 0.0 2.9 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EEB08308.1 - 0.0018 18.5 0.5 0.14 12.5 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Dirigent PF03018.14 EEB08308.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Dirigent-like protein Cofilin_ADF PF00241.20 EEB08309.1 - 9.4e-22 77.1 0.0 1.2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein KorB PF08535.10 EEB08309.1 - 0.082 12.9 0.1 12 6.0 0.0 2.1 2 0 0 2 2 2 0 KorB domain FAD_binding_6 PF00970.24 EEB08310.1 - 2.1e-05 24.8 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEB08310.1 - 0.016 15.8 0.0 0.053 14.2 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EEB08310.1 - 0.059 13.5 0.1 0.63 10.2 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain AA_kinase PF00696.28 EEB08311.1 - 4.9e-38 131.1 0.4 6.2e-38 130.7 0.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EEB08311.1 - 2.2e-17 62.7 0.1 5.4e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 PUA domain Nop52 PF05997.12 EEB08312.1 - 2.9e-64 216.8 0.7 3.7e-64 216.5 0.7 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Ribosomal_L27A PF00828.19 EEB08313.1 - 5.9e-32 111.0 0.1 8.3e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A LSM PF01423.22 EEB08314.1 - 4.8e-11 42.2 0.1 1.5e-10 40.6 0.1 1.7 1 1 0 1 1 1 1 LSM domain DUF4335 PF14233.6 EEB08314.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) GTP_EFTU PF00009.27 EEB08315.1 - 1.3e-57 194.5 1.9 1.9e-57 194.0 1.9 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEB08315.1 - 5e-29 100.9 0.0 1.3e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEB08315.1 - 2.9e-16 59.6 3.7 3.1e-16 59.5 2.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB08315.1 - 1.1e-05 25.5 0.2 2.6e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EEB08315.1 - 0.0039 16.8 0.8 0.0087 15.7 0.2 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Alba PF01918.21 EEB08315.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 Alba PduV-EutP PF10662.9 EEB08315.1 - 0.015 15.1 0.6 5.7 6.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EEB08315.1 - 0.12 12.0 4.4 4 7.0 4.4 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Prefoldin_2 PF01920.20 EEB08316.1 - 9.6e-10 38.4 9.6 1.2e-09 38.0 9.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit XhlA PF10779.9 EEB08316.1 - 0.042 14.1 1.3 0.042 14.1 1.3 2.3 2 1 0 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 EEB08316.1 - 0.091 12.9 7.4 0.83 9.8 0.9 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 EEB08316.1 - 0.19 12.1 6.9 2.5 8.5 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 EEB08316.1 - 0.7 10.4 7.6 0.13 12.7 2.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fis1_TPR_C PF14853.6 EEB08317.1 - 3.1e-20 72.0 2.6 3.1e-20 72.0 2.6 1.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EEB08317.1 - 2.6e-13 49.4 0.3 5.3e-13 48.4 0.3 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EEB08317.1 - 0.00012 21.9 2.0 0.00036 20.4 1.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB08317.1 - 0.00098 19.6 0.8 0.0035 17.9 0.7 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08317.1 - 0.049 14.5 0.1 0.1 13.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEB08317.1 - 0.049 13.8 0.1 0.074 13.2 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.8 EEB08317.1 - 0.073 12.0 0.2 0.083 11.8 0.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EEB08317.1 - 0.095 13.2 0.2 0.14 12.7 0.2 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08317.1 - 0.099 12.5 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AI-2E_transport PF01594.16 EEB08317.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter SPO22 PF08631.10 EEB08317.1 - 0.13 11.8 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like EF-hand_4 PF12763.7 EEB08318.1 - 4.5e-39 132.6 0.0 3.5e-38 129.7 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 EEB08318.1 - 9e-20 71.7 5.9 3.4e-19 69.8 5.9 2.0 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_8 PF13833.6 EEB08318.1 - 2.5e-05 24.0 0.2 6.2e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EEB08318.1 - 3.1e-05 24.3 0.7 0.00016 22.0 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB08318.1 - 4.3e-05 22.8 2.4 0.00011 21.5 1.1 2.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EEB08318.1 - 0.004 17.0 0.6 0.068 13.1 0.7 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_9 PF14658.6 EEB08318.1 - 0.0072 16.6 0.1 0.071 13.4 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain LRR_3 PF07725.12 EEB08318.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 Leucine Rich Repeat MRF_C2 PF13888.6 EEB08318.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 FAM76 PF16046.5 EEB08318.1 - 0.058 12.8 3.4 0.085 12.2 3.4 1.2 1 0 0 1 1 1 0 FAM76 protein RL10P_insert PF17777.1 EEB08319.1 - 1.8e-22 79.1 0.0 3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EEB08319.1 - 3.1e-20 72.2 0.0 4.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Sedlin_N PF04628.13 EEB08320.1 - 8.7e-49 165.0 0.6 9.8e-49 164.8 0.6 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EEB08320.1 - 1.5e-11 44.4 0.6 3e-11 43.4 0.6 1.5 1 1 0 1 1 1 1 Sybindin-like family RNA_polI_A34 PF08208.11 EEB08321.1 - 2.4e-10 40.8 13.1 2.4e-10 40.8 13.1 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CALM_bind PF16025.5 EEB08321.1 - 0.054 14.0 0.0 0.054 14.0 0.0 2.8 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding LSM PF01423.22 EEB08322.1 - 2.3e-17 62.4 0.1 2.7e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEB08322.1 - 0.00087 18.9 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 EEB08323.1 - 1e-23 84.0 4.3 2.1e-23 83.0 0.1 3.4 3 2 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EEB08323.1 - 9.7e-10 38.2 1.6 6.2e-08 32.4 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF4800 PF16057.5 EEB08323.1 - 0.0023 17.3 0.1 0.0062 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) HEAT PF02985.22 EEB08323.1 - 0.0024 18.0 0.3 0.61 10.5 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat DUF4020 PF13212.6 EEB08323.1 - 0.012 15.4 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) DUF1722 PF08349.11 EEB08323.1 - 0.024 14.9 0.0 5.1 7.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) HEAT_EZ PF13513.6 EEB08323.1 - 0.033 14.7 0.1 9.8 6.8 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat AMP-binding PF00501.28 EEB08324.1 - 1.4e-97 327.0 0.0 1.8e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEB08324.1 - 0.097 13.7 0.0 0.26 12.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain eIF3g PF12353.8 EEB08325.1 - 2e-43 147.7 1.6 2.8e-43 147.3 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EEB08325.1 - 2e-18 66.0 0.0 4e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB08325.1 - 0.002 17.9 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-C2H2 PF00096.26 EEB08326.2 - 3.7e-09 36.6 12.9 0.00038 20.8 3.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEB08326.2 - 8.9e-09 35.4 15.4 3.4e-05 24.1 4.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEB08326.2 - 0.00033 21.2 10.7 0.12 13.3 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EEB08326.2 - 0.17 12.6 0.1 0.17 12.6 0.1 2.5 3 0 0 3 3 3 0 FOXP coiled-coil domain ATP-sulfurylase PF01747.17 EEB08327.1 - 3.9e-90 301.0 0.1 5.3e-90 300.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EEB08327.1 - 1.4e-48 164.6 0.0 2.4e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain 60KD_IMP PF02096.20 EEB08328.1 - 7.4e-12 45.5 0.4 8.6e-12 45.3 0.4 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2975 PF11188.8 EEB08328.1 - 0.015 15.2 0.3 0.041 13.8 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ADH_zinc_N PF00107.26 EEB08329.1 - 7.8e-22 77.6 0.0 1.4e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB08329.1 - 1.2e-15 58.7 0.0 2.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEB08329.1 - 2.7e-12 46.6 0.3 7.6e-12 45.1 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EEB08329.1 - 0.00031 20.2 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N_2 PF16884.5 EEB08329.1 - 0.00087 19.2 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase T4bSS_IcmS PF12608.8 EEB08329.1 - 0.011 16.1 0.1 3.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment C2-C2_1 PF11618.8 EEB08329.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 RELT PF12606.8 EEB08329.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF4547 PF15080.6 EEB08329.1 - 0.081 12.6 0.0 0.85 9.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4547) gpW PF02831.15 EEB08329.1 - 1.5 8.8 4.8 32 4.5 0.2 3.4 4 0 0 4 4 4 0 gpW Ist1 PF03398.14 EEB08330.1 - 0.0023 17.9 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DEAD PF00270.29 EEB08331.2 - 1.6e-41 142.0 0.0 7.8e-41 139.7 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB08331.2 - 2.8e-22 79.1 0.0 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08331.2 - 1.5e-09 38.1 0.0 4.5e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EEB08331.2 - 0.0015 17.3 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.14 EEB08331.2 - 0.088 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 EEB08331.2 - 0.1 12.9 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain EAF PF09816.9 EEB08332.1 - 1.6e-25 89.4 0.1 3.4e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Hamartin PF04388.12 EEB08332.1 - 0.7 8.5 8.8 0.81 8.3 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein PP2C PF00481.21 EEB08333.1 - 6.1e-86 288.2 0.0 7.8e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Recep_L_domain PF01030.24 EEB08334.1 - 2e-10 40.8 5.3 0.0022 18.1 0.2 5.0 1 1 4 5 5 5 4 Receptor L domain LRR_5 PF13306.6 EEB08334.1 - 0.0003 20.7 1.5 0.38 10.7 0.1 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ecm33 PF12454.8 EEB08334.1 - 0.01 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LAG1-DNAbind PF09271.11 EEB08335.2 - 9.4e-29 101.0 0.0 9.4e-29 101.0 0.0 1.7 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 EEB08335.2 - 2.7e-24 86.2 0.0 4.5e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Chorismate_synt PF01264.21 EEB08336.1 - 6.2e-140 465.5 0.0 7.2e-140 465.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Pkinase PF00069.25 EEB08337.2 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08337.2 - 8.6e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB08337.2 - 5.2e-06 25.5 0.0 9.2e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEB08337.2 - 1.3e-05 24.6 0.0 6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SET PF00856.28 EEB08338.1 - 1.4e-12 48.3 0.2 1.8e-10 41.4 0.2 2.1 1 1 0 1 1 1 1 SET domain DENN PF02141.21 EEB08339.1 - 2.3e-42 145.1 1.4 2.3e-42 145.1 1.4 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EEB08339.1 - 4.4e-15 56.2 2.1 1.1e-14 55.0 0.8 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 EEB08339.1 - 7.7e-05 22.6 0.9 0.00023 21.1 0.9 1.9 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 EEB08339.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis LMBR1 PF04791.16 EEB08340.1 - 4.7 6.0 10.0 4.9 5.9 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UCR_14kD PF02271.16 EEB08341.1 - 2.2e-40 136.6 0.6 2.6e-40 136.4 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SAM_KSR1 PF13543.6 EEB08341.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.6 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Ima1_N PF09779.9 EEB08342.1 - 1.1e-32 113.7 4.7 1.1e-32 113.7 4.7 2.3 2 1 0 2 2 2 1 Ima1 N-terminal domain PyrI_C PF02748.15 EEB08342.1 - 0.017 15.0 2.1 0.09 12.7 0.2 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-RRPl_C4 PF17026.5 EEB08342.1 - 0.048 13.8 4.3 0.13 12.4 4.3 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 EEB08342.1 - 0.074 13.1 5.9 3 8.0 0.2 3.2 3 1 0 3 3 3 0 Double zinc ribbon Vps36-NZF-N PF16988.5 EEB08342.1 - 0.099 12.1 1.6 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GET2 PF08690.10 EEB08342.1 - 1.4 8.5 5.0 4.1 7.0 5.0 1.8 1 1 0 1 1 1 0 GET complex subunit GET2 zf-Sec23_Sec24 PF04810.15 EEB08342.1 - 5 7.3 8.6 1.8 8.7 2.4 3.0 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger adh_short PF00106.25 EEB08343.1 - 7.2e-49 165.9 2.0 8.4e-49 165.7 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB08343.1 - 4.8e-32 111.4 0.4 5.6e-32 111.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB08343.1 - 3.3e-14 53.2 0.2 4.2e-14 52.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEB08343.1 - 1.2e-05 24.6 2.0 6.2e-05 22.3 2.0 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EEB08343.1 - 0.024 14.1 0.2 0.042 13.3 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EEB08343.1 - 0.033 13.9 0.5 0.072 12.9 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pex24p PF06398.11 EEB08344.1 - 1.1e-12 47.6 13.5 6.1e-07 28.7 0.2 3.0 1 1 2 3 3 3 3 Integral peroxisomal membrane peroxin Lectin_N PF03954.14 EEB08344.1 - 0.015 15.1 0.3 0.039 13.7 0.1 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Aldo_ket_red PF00248.21 EEB08345.1 - 0.0013 18.0 0.1 0.0021 17.3 0.1 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Fasciclin PF02469.22 EEB08345.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Fasciclin domain Ribos_L4_asso_C PF14374.6 EEB08345.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain AAA_11 PF13086.6 EEB08346.1 - 4.6e-59 200.3 0.0 2.9e-58 197.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EEB08346.1 - 1.2e-56 191.5 0.1 2.4e-56 190.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEB08346.1 - 3.5e-14 53.0 0.0 3.5e-12 46.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB08346.1 - 2.1e-11 44.4 0.0 2.5e-10 40.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EEB08346.1 - 1.6e-09 37.8 1.3 0.0068 16.2 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EEB08346.1 - 8.5e-06 25.9 0.0 3.9e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EEB08346.1 - 0.0001 21.7 1.0 0.0022 17.3 1.0 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 EEB08346.1 - 0.0002 20.9 2.1 0.24 10.7 0.0 2.9 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 EEB08346.1 - 0.00028 20.8 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 EEB08346.1 - 0.00038 20.7 0.3 0.0079 16.5 0.3 2.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EEB08346.1 - 0.0018 17.9 0.0 0.014 15.0 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EEB08346.1 - 0.003 18.0 0.1 0.0084 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EEB08346.1 - 0.0036 16.4 0.1 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 EEB08346.1 - 0.0042 16.9 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 EEB08346.1 - 0.0078 16.6 0.4 0.044 14.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EEB08346.1 - 0.023 14.8 0.1 0.083 13.0 0.0 2.1 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Flavi_DEAD PF07652.14 EEB08346.1 - 0.025 14.6 0.1 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain T_hemolysin PF12261.8 EEB08346.1 - 0.029 14.2 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin AAA_33 PF13671.6 EEB08346.1 - 0.044 13.9 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EEB08346.1 - 0.044 13.2 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EEB08346.1 - 0.07 12.8 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EEB08346.1 - 0.092 12.3 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain TK PF00265.18 EEB08346.1 - 0.093 12.6 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Thymidine kinase ABC_tran PF00005.27 EEB08346.1 - 0.12 12.9 0.1 1.5 9.4 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 EEB08347.2 - 1.4e-126 417.1 0.0 4.6e-21 75.3 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EEB08347.2 - 3.2e-38 130.2 4.3 1.7e-11 44.3 2.0 5.1 4 0 0 4 4 4 3 Midasin AAA lid domain AAA PF00004.29 EEB08347.2 - 4e-30 105.0 0.6 0.0028 18.1 0.0 7.8 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEB08347.2 - 8e-30 103.7 2.9 2.5e-05 23.9 0.0 6.9 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_3 PF07726.11 EEB08347.2 - 1.2e-29 102.9 0.0 1.2e-09 38.1 0.0 8.3 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EEB08347.2 - 6.6e-29 100.1 0.0 7.6e-26 90.3 0.0 3.4 2 0 0 2 2 2 1 Midasin AAA lid domain Dynein_heavy PF03028.15 EEB08347.2 - 6e-22 78.0 0.0 0.00047 20.2 0.0 7.7 7 0 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EEB08347.2 - 5.9e-21 75.6 8.7 0.0029 18.0 0.3 7.9 6 2 0 6 6 6 4 AAA ATPase domain AAA_6 PF12774.7 EEB08347.2 - 6.6e-21 74.6 0.4 0.00033 19.7 0.1 8.9 8 0 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EEB08347.2 - 2.7e-19 69.8 0.5 0.01 16.1 0.0 7.6 6 0 0 6 6 6 4 AAA domain AAA_18 PF13238.6 EEB08347.2 - 1.7e-18 67.4 3.4 0.00093 19.7 0.0 6.9 6 0 0 6 6 6 3 AAA domain T2SSE PF00437.20 EEB08347.2 - 9.6e-17 60.9 2.0 0.0015 17.7 0.0 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_14 PF13173.6 EEB08347.2 - 5.4e-16 58.8 0.0 0.0054 16.8 0.0 8.1 7 1 0 8 8 7 2 AAA domain Sigma54_activat PF00158.26 EEB08347.2 - 4.7e-15 55.7 0.1 0.5 10.0 0.0 6.9 6 0 0 6 6 6 3 Sigma-54 interaction domain TsaE PF02367.17 EEB08347.2 - 2.8e-14 53.2 6.2 0.15 12.1 0.0 7.0 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EEB08347.2 - 5.5e-14 52.5 3.0 0.0021 18.2 0.0 7.2 7 0 0 7 7 7 2 Sigma-54 interaction domain AAA_30 PF13604.6 EEB08347.2 - 9.1e-14 51.6 0.1 0.086 12.6 0.0 7.0 7 3 0 7 7 6 3 AAA domain AAA_33 PF13671.6 EEB08347.2 - 1.4e-13 51.2 0.0 0.97 9.6 0.0 6.8 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 EEB08347.2 - 2.8e-13 50.6 2.5 0.074 13.6 0.0 6.6 6 0 0 6 6 5 3 ABC transporter RuvB_N PF05496.12 EEB08347.2 - 3.5e-13 49.6 1.4 0.011 15.5 0.0 7.4 7 0 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EEB08347.2 - 5.5e-11 42.7 3.3 0.14 12.0 0.0 6.3 6 0 0 6 6 6 3 Rad17 P-loop domain Mg_chelatase PF01078.21 EEB08347.2 - 2.3e-10 40.2 2.0 9.5 5.5 0.1 8.9 9 1 0 10 10 9 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEB08347.2 - 3.6e-10 39.5 2.1 0.5 9.6 0.0 7.0 7 0 0 7 7 6 1 Zeta toxin AAA_25 PF13481.6 EEB08347.2 - 4.9e-10 39.3 1.8 0.071 12.7 0.0 6.0 6 0 0 6 6 5 2 AAA domain RNA_helicase PF00910.22 EEB08347.2 - 8.6e-10 39.0 4.2 0.53 10.7 0.0 7.4 7 0 0 7 7 7 1 RNA helicase RsgA_GTPase PF03193.16 EEB08347.2 - 4.8e-09 36.3 5.2 1.3 8.9 0.0 6.1 6 0 0 6 6 6 2 RsgA GTPase IstB_IS21 PF01695.17 EEB08347.2 - 6.6e-09 35.7 0.0 2.2 8.0 0.0 5.8 6 0 0 6 6 5 1 IstB-like ATP binding protein AAA_29 PF13555.6 EEB08347.2 - 5.8e-08 32.4 1.7 2.7 7.8 0.0 5.9 6 0 0 6 6 5 1 P-loop containing region of AAA domain NACHT PF05729.12 EEB08347.2 - 1.2e-07 31.8 10.4 2.7 7.9 0.3 6.3 5 0 0 5 5 5 2 NACHT domain AAA_24 PF13479.6 EEB08347.2 - 1.4e-07 31.4 3.6 1 9.0 0.1 6.1 6 0 0 6 6 5 1 AAA domain AAA_8 PF12780.7 EEB08347.2 - 5.8e-07 29.1 4.5 0.085 12.2 0.0 6.1 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 DUF815 PF05673.13 EEB08347.2 - 6.3e-07 28.8 1.0 2.1 7.4 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF815) ResIII PF04851.15 EEB08347.2 - 1.3e-06 28.5 1.0 9.5 6.2 0.0 6.1 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEB08347.2 - 1.8e-06 28.4 13.0 4.8 7.5 0.1 6.9 6 1 0 6 6 5 0 AAA domain AAA_28 PF13521.6 EEB08347.2 - 1.9e-06 28.2 10.3 5.3 7.3 0.0 6.5 6 0 0 6 6 6 0 AAA domain PduV-EutP PF10662.9 EEB08347.2 - 3e-06 27.0 7.4 0.14 11.9 0.1 5.4 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EEB08347.2 - 4.4e-06 26.4 7.8 0.45 10.1 0.4 5.7 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EEB08347.2 - 1.6e-05 24.9 0.1 2.1 8.2 0.0 5.4 5 0 0 5 5 4 1 ATPase domain predominantly from Archaea PhoH PF02562.16 EEB08347.2 - 3.9e-05 23.2 0.6 2.1 7.7 0.0 5.0 5 0 0 5 5 5 1 PhoH-like protein VWA PF00092.28 EEB08347.2 - 0.00016 22.0 0.5 0.00056 20.2 0.5 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain DEAD PF00270.29 EEB08347.2 - 0.00022 21.0 1.8 18 5.0 0.0 5.5 5 0 0 5 5 5 0 DEAD/DEAH box helicase SRPRB PF09439.10 EEB08347.2 - 0.00031 20.2 4.7 3.3 7.1 0.1 5.9 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit CbiA PF01656.23 EEB08347.2 - 0.00033 20.7 1.6 0.4 10.7 0.0 4.5 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EEB08347.2 - 0.00077 19.5 2.8 17 5.5 0.0 5.6 5 0 0 5 5 5 0 50S ribosome-binding GTPase DUF927 PF06048.11 EEB08347.2 - 0.0015 18.2 1.9 1.7 8.1 0.6 3.7 4 0 0 4 4 3 1 Domain of unknown function (DUF927) TniB PF05621.11 EEB08347.2 - 0.002 17.6 0.2 7.1 6.0 0.0 4.5 5 0 0 5 5 4 0 Bacterial TniB protein Roc PF08477.13 EEB08347.2 - 0.0025 18.0 4.6 55 4.0 0.0 6.0 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase VWA_2 PF13519.6 EEB08347.2 - 0.0051 17.4 0.9 0.049 14.3 0.2 3.2 2 0 0 2 2 1 1 von Willebrand factor type A domain FtsK_SpoIIIE PF01580.18 EEB08347.2 - 0.0056 16.1 0.9 8.8 5.6 0.1 3.9 4 0 0 4 4 3 0 FtsK/SpoIIIE family dNK PF01712.19 EEB08347.2 - 0.014 15.2 5.7 48 3.7 0.0 5.7 5 0 0 5 5 5 0 Deoxynucleoside kinase NTPase_1 PF03266.15 EEB08347.2 - 0.02 14.8 11.8 18 5.2 0.2 6.0 6 0 0 6 6 5 0 NTPase cobW PF02492.19 EEB08347.2 - 0.078 12.6 9.1 1.7 8.2 0.0 5.1 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 EEB08347.2 - 0.085 12.6 1.5 45 3.7 0.0 4.0 4 0 0 4 4 3 0 Cytidylate kinase CPT PF07931.12 EEB08347.2 - 0.085 12.7 0.7 70 3.2 0.0 4.7 3 1 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 EEB08347.2 - 0.09 13.3 0.0 0.09 13.3 0.0 8.8 7 1 0 8 8 6 0 AAA domain AAA_21 PF13304.6 EEB08347.2 - 0.11 12.2 14.4 0.21 11.3 0.0 5.4 6 0 0 6 6 4 0 AAA domain, putative AbiEii toxin, Type IV TA system vWA-TerF-like PF10138.9 EEB08347.2 - 0.2 11.8 4.0 0.099 12.7 0.1 2.6 3 0 0 3 3 1 0 vWA found in TerF C terminus AAA_31 PF13614.6 EEB08347.2 - 1.4 8.8 5.1 2 8.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 EEB08348.2 - 6.4e-39 134.2 8.1 6.4e-39 134.2 8.1 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEB08348.2 - 7.7e-22 78.3 0.0 1.7e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEB08348.2 - 1.1e-08 34.8 0.1 1.6e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Orthoreo_P10 PF07204.11 EEB08348.2 - 0.15 12.1 0.2 0.79 9.7 0.2 2.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SbcCD_C PF13558.6 EEB08348.2 - 0.19 12.0 0.2 3.3 8.0 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RRM_1 PF00076.22 EEB08349.2 - 3e-24 84.6 0.6 5.5e-12 45.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EEB08349.2 - 1.1e-05 25.3 0.9 0.066 13.2 0.1 2.5 2 0 0 2 2 2 2 RL domain DUF4523 PF15023.6 EEB08349.2 - 0.00098 19.0 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EEB08349.2 - 0.0036 17.4 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif Nab6_mRNP_bdg PF10567.9 EEB08349.2 - 0.027 14.0 0.9 20 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA-recognition motif RRM_occluded PF16842.5 EEB08349.2 - 0.038 13.9 0.0 3.2 7.7 0.0 3.4 4 0 0 4 4 4 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEB08349.2 - 0.072 13.1 1.8 52 4.0 0.1 3.8 3 1 1 4 4 4 0 Nup53/35/40-type RNA recognition motif DNA_pol3_a_NI PF14480.6 EEB08349.2 - 0.11 12.5 0.8 11 6.1 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III polC-type N-terminus I Calcipressin PF04847.12 EEB08349.2 - 0.25 11.1 1.6 36 4.0 0.1 3.1 2 1 1 3 3 3 0 Calcipressin Sec1 PF00995.23 EEB08350.2 - 2.9e-127 426.3 3.2 3.4e-127 426.1 3.2 1.0 1 0 0 1 1 1 1 Sec1 family UAE_UbL PF14732.6 EEB08350.2 - 0.013 16.1 1.4 0.12 12.9 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain FlxA PF14282.6 EEB08351.2 - 0.058 13.4 4.2 0.27 11.2 4.2 2.2 1 0 0 1 1 1 0 FlxA-like protein Pkinase PF00069.25 EEB08352.1 - 1.3e-73 247.6 0.5 1.9e-73 247.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain AdenylateSensor PF16579.5 EEB08352.1 - 2.6e-42 144.0 0.0 5.4e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 EEB08352.1 - 3.2e-39 134.8 0.0 6.7e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 EEB08352.1 - 7.3e-13 48.4 1.9 2e-12 47.0 1.9 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EEB08352.1 - 1.7e-08 34.2 0.0 3.8e-07 29.7 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEB08352.1 - 0.0021 17.1 0.2 0.0021 17.1 0.2 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EEB08352.1 - 0.0039 16.6 0.4 0.0087 15.4 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EEB08352.1 - 0.0047 15.8 0.1 0.0093 14.8 0.1 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Mlp PF03304.13 EEB08352.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Mlp lipoprotein family APH PF01636.23 EEB08352.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tom7 PF08038.12 EEB08353.1 - 3.1e-20 71.5 0.8 3.6e-20 71.3 0.8 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.11 EEB08353.1 - 0.16 12.2 0.2 0.44 10.8 0.3 1.7 2 1 0 2 2 2 0 NUMOD3 motif (2 copies) Mito_carr PF00153.27 EEB08354.2 - 2.3e-44 149.2 5.4 2.1e-16 59.6 0.2 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein UME PF08064.13 EEB08355.2 - 0.014 15.3 8.1 0.69 9.9 0.9 4.9 3 0 0 3 3 3 0 UME (NUC010) domain HEAT PF02985.22 EEB08355.2 - 0.039 14.2 0.4 65 4.2 0.0 5.2 3 0 0 3 3 3 0 HEAT repeat ICA69 PF04629.14 EEB08355.2 - 6.5 7.0 11.1 1.8 8.8 2.7 2.4 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain DUF1640 PF07798.11 EEB08356.1 - 2.1e-41 141.9 6.5 2.8e-41 141.5 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phosphorylase PF00343.20 EEB08356.1 - 0.0055 15.0 0.2 0.0078 14.5 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Phosphodiest PF01663.22 EEB08357.1 - 3.9e-16 59.6 0.3 5.7e-16 59.0 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EEB08357.1 - 5e-07 29.3 0.6 9.7e-07 28.4 0.6 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EEB08357.1 - 0.0084 15.5 0.2 0.018 14.5 0.2 1.5 1 0 0 1 1 1 1 Sulfatase DUF3974 PF13120.6 EEB08357.1 - 1.1 9.4 6.3 0.32 11.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) CRT10 PF08728.10 EEB08358.2 - 9.4e-13 47.2 5.4 6.4e-06 24.6 1.0 2.7 1 1 0 2 2 2 2 CRT10 WD40 PF00400.32 EEB08358.2 - 0.00061 20.6 0.5 0.0033 18.2 0.5 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF3402 PF11882.8 EEB08359.2 - 5.7e-41 141.1 13.4 2.7e-24 86.1 3.5 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) FA_hydroxylase PF04116.13 EEB08360.1 - 1.9e-21 76.8 18.9 1.9e-21 76.8 18.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TatC PF00902.18 EEB08360.1 - 0.081 12.7 5.9 0.18 11.6 5.9 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) UPF0220 PF05255.11 EEB08362.2 - 6.5e-58 194.9 6.2 7.9e-58 194.7 6.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.25 EEB08363.1 - 3.6e-63 213.4 0.0 4.3e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08363.1 - 4.7e-25 88.3 0.0 7.6e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB08363.1 - 0.00012 22.1 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEB08363.1 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB08363.1 - 0.0062 15.9 0.2 0.0097 15.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEB08363.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EEB08363.1 - 0.053 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 EEB08363.1 - 0.091 11.6 0.3 1 8.1 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) HTH_37 PF13744.6 EEB08363.1 - 0.13 12.2 0.1 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Porin_3 PF01459.22 EEB08364.1 - 1.1e-82 277.6 0.0 1.3e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CorA PF01544.18 EEB08365.1 - 2e-42 145.5 0.0 2.8e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EEB08365.1 - 0.048 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CBP4 PF07960.11 EEB08366.1 - 3.4e-16 59.3 0.1 3.4e-16 59.3 0.1 1.0 1 0 0 1 1 1 1 CBP4 ATP-synt_E PF05680.12 EEB08366.1 - 0.0014 18.9 0.5 0.0016 18.7 0.5 1.1 1 0 0 1 1 1 1 ATP synthase E chain Zn_clus PF00172.18 EEB08367.1 - 0.0067 16.5 17.0 0.012 15.8 17.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.9 EEB08368.1 - 2.8e-17 63.3 2.7 2.8e-17 63.3 2.7 3.4 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ubiquitin PF00240.23 EEB08370.1 - 3.4e-12 45.9 0.2 7.1e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EEB08370.1 - 0.0077 16.8 0.1 0.021 15.4 0.1 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB08370.1 - 0.042 14.0 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3899 PF13038.6 EEB08370.1 - 0.088 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Menin PF05053.13 EEB08370.1 - 1.4 7.2 3.6 2.7 6.3 3.6 1.4 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EEB08370.1 - 9.5 4.6 7.3 20 3.6 7.3 1.5 1 0 0 1 1 1 0 Macoilin family PS_Dcarbxylase PF02666.15 EEB08371.1 - 4.7e-71 238.5 0.0 5.9e-70 234.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 EEB08371.1 - 0.03 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Cyclin_N PF00134.23 EEB08372.1 - 7.3e-21 74.2 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB08372.1 - 3.5e-06 27.1 0.0 7.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Sec34 PF04136.15 EEB08373.2 - 0.053 13.4 13.8 0.72 9.7 0.6 3.7 2 1 0 3 3 3 0 Sec34-like family TssO PF17561.2 EEB08374.1 - 0.017 15.2 0.2 0.018 15.1 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Translin PF01997.16 EEB08374.1 - 0.029 14.3 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Translin family Baculo_PEP_C PF04513.12 EEB08374.1 - 0.052 13.6 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 EEB08374.1 - 0.06 13.2 1.1 0.068 13.0 1.1 1.1 1 0 0 1 1 1 0 Heat shock factor binding protein 1 TbpB_B_D PF01298.18 EEB08374.1 - 0.068 13.6 0.2 0.068 13.6 0.2 1.1 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Cation_efflux PF01545.21 EEB08375.1 - 3.2e-10 40.1 12.5 4.4e-10 39.6 12.5 1.2 1 0 0 1 1 1 1 Cation efflux family DUF4395 PF14340.6 EEB08375.1 - 0.55 10.6 5.9 1 9.7 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Pkinase PF00069.25 EEB08376.1 - 7.4e-44 150.1 0.0 9.6e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08376.1 - 1.2e-25 90.3 0.0 1.5e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB08376.1 - 6.7e-06 26.2 1.4 0.014 15.3 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EEB08376.1 - 0.00023 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB08376.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB08376.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sterol_MT_C PF08498.10 EEB08377.1 - 1.2e-25 89.6 1.4 2e-25 88.9 1.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EEB08377.1 - 3.9e-21 75.5 0.0 8e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08377.1 - 5.6e-18 65.4 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08377.1 - 2.1e-15 56.8 0.0 3.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08377.1 - 7.2e-14 51.9 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08377.1 - 1e-09 39.0 0.0 3.6e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEB08377.1 - 1.2e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EEB08377.1 - 9.7e-09 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EEB08377.1 - 2.3e-06 27.3 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EEB08377.1 - 0.0032 17.3 0.0 0.029 14.2 0.0 2.0 1 1 1 2 2 2 1 Hypothetical methyltransferase CDC48_2 PF02933.17 EEB08377.1 - 0.022 14.5 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Methyltransf_29 PF03141.16 EEB08377.1 - 0.025 13.1 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EEB08377.1 - 0.041 13.6 0.1 1.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EEB08377.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EEB08377.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain BolA PF01722.18 EEB08378.1 - 1.2e-26 92.8 0.4 2.4e-26 91.8 0.1 1.6 1 1 1 2 2 2 1 BolA-like protein HA2 PF04408.23 EEB08379.1 - 2.2e-14 53.6 0.0 2.2e-14 53.6 0.0 3.0 4 0 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEB08379.1 - 4.9e-14 52.4 0.0 1.4e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEB08379.1 - 3.8e-13 49.8 1.0 1.7e-12 47.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB08379.1 - 1.7e-08 34.5 0.1 5.1e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB08379.1 - 2.1e-05 24.8 0.1 7.1e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain RWD PF05773.22 EEB08379.1 - 0.00019 21.7 2.6 0.00034 20.9 1.2 2.2 2 0 0 2 2 2 1 RWD domain AAA_19 PF13245.6 EEB08379.1 - 0.0035 17.7 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEB08379.1 - 0.0036 16.4 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EEB08379.1 - 0.011 15.0 0.0 0.68 9.2 0.0 3.0 2 1 1 3 3 3 0 Zeta toxin ResIII PF04851.15 EEB08379.1 - 0.011 15.7 0.2 0.21 11.5 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EEB08379.1 - 0.013 15.6 0.0 0.16 12.0 0.0 2.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EEB08379.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EEB08379.1 - 0.021 15.4 0.9 0.4 11.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.6 EEB08379.1 - 0.029 14.1 0.2 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EEB08379.1 - 0.05 13.3 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEB08379.1 - 0.095 12.0 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 EEB08379.1 - 0.29 11.5 1.3 0.97 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain dsrm PF00035.26 EEB08379.1 - 0.8 10.5 5.5 15 6.4 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif ABC_tran PF00005.27 EEB08380.1 - 2.6e-40 138.1 8.9 1.6e-20 74.1 0.0 3.6 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 EEB08380.1 - 2.4e-16 60.4 13.9 1e-05 25.5 0.0 5.1 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EEB08380.1 - 4e-09 36.4 5.3 4e-09 36.4 5.3 4.6 3 1 1 4 4 2 1 ABC transporter AAA_29 PF13555.6 EEB08380.1 - 6.8e-09 35.3 0.0 0.00091 18.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EEB08380.1 - 2e-07 30.7 18.2 0.01 15.3 0.1 5.3 6 0 0 6 6 5 4 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EEB08380.1 - 4.9e-06 26.5 0.0 0.00044 20.2 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EEB08380.1 - 6.6e-05 23.2 1.8 0.18 12.1 0.0 3.9 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EEB08380.1 - 0.00017 22.0 0.0 0.049 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EEB08380.1 - 0.00042 20.1 28.6 0.3 10.8 0.1 5.3 5 1 0 5 5 5 1 AAA ATPase domain NACHT PF05729.12 EEB08380.1 - 0.00071 19.5 0.0 0.77 9.7 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA PF00004.29 EEB08380.1 - 0.00078 19.9 3.1 0.15 12.5 0.0 4.2 4 2 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EEB08380.1 - 0.0018 17.9 0.2 0.093 12.3 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EEB08380.1 - 0.0025 17.7 0.1 0.23 11.4 0.1 2.6 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 EEB08380.1 - 0.0027 17.8 2.6 0.02 14.9 0.1 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EEB08380.1 - 0.0046 16.6 0.0 4.7 6.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EEB08380.1 - 0.0057 16.8 0.0 0.5 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEB08380.1 - 0.0092 16.5 0.1 0.0092 16.5 0.1 6.0 4 2 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EEB08380.1 - 0.012 15.9 1.8 0.88 9.8 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.6 EEB08380.1 - 0.012 15.3 1.5 0.71 9.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EEB08380.1 - 0.015 15.3 0.1 7.7 6.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EEB08380.1 - 0.015 15.3 0.0 2 8.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EEB08380.1 - 0.018 15.0 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EEB08380.1 - 0.036 13.1 0.0 0.47 9.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EEB08380.1 - 0.062 12.6 0.2 0.68 9.2 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EEB08380.1 - 0.092 12.3 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EEB08380.1 - 0.095 13.1 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EEB08380.1 - 0.097 13.0 0.1 7.4 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 EEB08380.1 - 0.11 12.8 0.5 23 5.3 0.0 3.8 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EEB08380.1 - 0.54 9.9 9.5 0.68 9.6 0.0 3.5 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EEB08380.1 - 1.7 9.2 0.0 1.7 9.2 0.0 4.7 5 1 0 5 5 3 0 AAA domain DUF87 PF01935.17 EEB08380.1 - 7.4 6.6 17.9 7.9 6.5 0.0 4.4 4 1 0 4 4 4 0 Helicase HerA, central domain MeaB PF03308.16 EEB08380.1 - 7.6 5.4 7.4 52 2.7 0.0 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRKCSH-like PF12999.7 EEB08381.1 - 4.6e-78 261.0 8.1 4.6e-78 261.0 8.1 2.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EEB08381.1 - 2.1e-69 232.1 0.6 5e-69 230.9 0.6 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 EEB08381.1 - 0.0033 17.6 14.9 0.19 11.9 4.4 2.7 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A RAMPs PF03787.15 EEB08381.1 - 0.038 14.0 0.3 0.061 13.4 0.3 1.2 1 0 0 1 1 1 0 RAMP superfamily Imm6 PF14434.6 EEB08381.1 - 1.2 9.1 10.2 0.075 13.0 2.5 2.7 3 0 0 3 3 3 0 Immunity protein Imm6 DUF948 PF06103.11 EEB08381.1 - 7.6 6.9 7.3 41 4.5 0.0 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 EEB08382.1 - 1.9e-30 106.1 19.7 2.7e-30 105.6 19.7 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EEB08382.1 - 1.7e-13 50.3 0.6 1.7e-13 50.3 0.6 2.0 2 0 0 2 2 1 1 SNARE domain BLOC1_2 PF10046.9 EEB08382.1 - 0.0081 16.4 4.5 1.9 8.9 0.2 3.4 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vac_Fusion PF02346.16 EEB08382.1 - 0.017 14.8 3.3 0.71 9.5 0.0 2.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 ATP-grasp_5 PF13549.6 EEB08382.1 - 0.017 14.6 1.6 0.1 12.0 0.1 2.5 2 1 0 2 2 2 0 ATP-grasp domain MCPsignal PF00015.21 EEB08382.1 - 0.026 14.3 7.9 0.034 14.0 0.4 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE PF05008.15 EEB08382.1 - 0.034 14.5 0.4 0.034 14.5 0.4 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DASH_Dad3 PF08656.10 EEB08382.1 - 0.041 14.0 0.1 0.4 10.8 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Prominin PF05478.11 EEB08382.1 - 0.044 11.8 8.9 0.038 12.0 0.3 2.1 2 0 0 2 2 2 0 Prominin NPV_P10 PF05531.12 EEB08382.1 - 0.054 14.0 8.5 0.38 11.3 1.8 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YfdX PF10938.8 EEB08382.1 - 0.055 13.4 5.3 2.1 8.2 0.1 2.7 2 1 0 2 2 2 0 YfdX protein DUF2207 PF09972.9 EEB08382.1 - 0.094 11.5 0.1 0.17 10.6 0.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SMBP PF16785.5 EEB08382.1 - 0.11 12.7 3.8 11 6.2 1.9 3.1 2 1 0 2 2 2 0 Small metal-binding protein Phasin_2 PF09361.10 EEB08382.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.0 3 1 0 3 3 3 0 Phasin protein Cnd1 PF12717.7 EEB08382.1 - 0.16 12.0 4.1 1.6 8.7 0.9 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TraF_2 PF13729.6 EEB08382.1 - 0.16 11.3 1.4 0.18 11.1 0.2 1.7 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein FlaC_arch PF05377.11 EEB08382.1 - 0.18 12.2 3.0 26 5.3 0.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 EEB08382.1 - 0.19 12.2 5.5 0.27 11.7 0.4 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.11 EEB08382.1 - 0.28 10.6 9.5 0.074 12.6 3.5 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Herpes_US9 PF06072.11 EEB08382.1 - 0.34 10.8 1.6 0.74 9.7 1.6 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF1515 PF07439.11 EEB08382.1 - 1.3 9.0 11.3 0.84 9.7 0.8 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) TMPIT PF07851.13 EEB08382.1 - 2.6 7.2 10.5 2 7.6 1.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein Shisa PF13908.6 EEB08382.1 - 6.5 7.0 5.1 1.1 9.5 0.3 2.0 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PriC PF07445.12 EEB08382.1 - 8.4 6.3 18.8 1.1 9.1 12.7 2.0 1 1 1 2 2 2 0 Primosomal replication protein priC Acetyltransf_1 PF00583.25 EEB08383.1 - 2.6e-08 34.1 0.0 3.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB08383.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB08383.1 - 0.00027 21.3 0.1 0.00043 20.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB08383.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Fungal_trans PF04082.18 EEB08384.1 - 1e-30 106.7 2.7 2e-30 105.7 2.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB08384.1 - 5.1e-07 29.7 15.3 1.3e-06 28.5 15.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIN_6 PF17146.4 EEB08385.1 - 7.3e-32 109.7 0.0 2.2e-31 108.2 0.0 1.9 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EEB08385.1 - 8.1e-30 102.8 3.0 1.9e-29 101.6 3.0 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like WRNPLPNID PF15017.6 EEB08385.1 - 0.00083 20.2 8.6 0.0022 18.9 8.6 1.7 1 0 0 1 1 1 1 Putative WW-binding domain and destruction box Cwf_Cwc_15 PF04889.12 EEB08385.1 - 0.0036 17.1 2.5 0.0036 17.1 2.5 1.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Toxin_5 PF05294.13 EEB08385.1 - 6.5 7.3 7.0 3.5 8.1 3.4 2.1 2 0 0 2 2 2 0 Scorpion short toxin CLASP_N PF12348.8 EEB08386.1 - 7.8e-09 35.4 0.2 5e-08 32.8 0.2 2.1 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EEB08386.1 - 5.3e-07 29.3 1.0 0.71 10.3 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EEB08386.1 - 4.4e-05 23.8 0.1 0.14 12.5 0.0 4.1 2 1 2 4 4 4 2 HEAT repeats Phage_GPO PF05929.11 EEB08386.1 - 0.011 15.4 1.3 0.011 15.4 1.3 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TAN PF11640.8 EEB08386.1 - 0.018 15.2 0.3 0.079 13.1 0.3 2.2 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Spc24 PF08286.11 EEB08386.1 - 0.023 14.9 0.6 6.6 7.0 0.8 3.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PDT PF00800.18 EEB08386.1 - 0.038 13.8 0.8 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydratase DUF3450 PF11932.8 EEB08386.1 - 0.62 9.3 13.2 0.1 11.9 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Rab5-bind PF09311.11 EEB08386.1 - 1 8.7 14.2 0.054 12.9 8.3 1.8 2 0 0 2 2 2 0 Rabaptin-like protein Ribosomal_L29 PF00831.23 EEB08386.1 - 1.2 9.1 6.1 0.18 11.8 1.2 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein FemAB PF02388.16 EEB08386.1 - 2.9 6.7 5.2 6.1 5.6 5.2 1.5 1 0 0 1 1 1 0 FemAB family LPP PF04728.13 EEB08386.1 - 9.7 6.7 8.1 1.1 9.6 0.9 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Arrestin_N PF00339.29 EEB08387.1 - 0.00023 21.2 0.1 0.00043 20.3 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EEB08387.1 - 0.0017 18.8 0.4 0.3 11.5 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain CENP-T_C PF15511.6 EEB08388.1 - 6.7e-09 35.8 0.1 8.2e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EEB08388.1 - 4e-06 27.0 0.1 6.9e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB08388.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EEB08388.1 - 1.6e-05 25.0 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EEB08388.1 - 0.0001 22.6 0.1 0.00013 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEB08388.1 - 0.0065 16.5 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEB08388.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EEB08388.1 - 0.16 12.5 0.1 0.25 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 EEB08389.1 - 1.2e-51 174.5 1.1 1.3e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEB08389.1 - 7.3e-06 26.3 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEB08389.1 - 0.00018 21.6 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEB08389.1 - 0.00068 20.2 2.4 0.00087 19.9 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEB08389.1 - 0.0086 16.3 0.2 0.016 15.5 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sfi1 PF08457.10 EEB08390.1 - 2.4e-71 241.0 92.5 5.4e-70 236.5 84.1 2.3 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF2115 PF09888.9 EEB08390.1 - 0.074 13.6 0.1 0.074 13.6 0.1 3.4 4 1 1 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2115) DnaA_N PF11638.8 EEB08390.1 - 0.97 9.2 7.9 0.69 9.7 0.2 4.1 3 1 1 4 4 4 0 DnaA N-terminal domain tRNA-synt_1 PF00133.22 EEB08391.1 - 4.9e-229 761.6 1.1 8.2e-229 760.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEB08391.1 - 2.3e-26 92.6 0.0 6.4e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEB08391.1 - 5.6e-17 61.6 1.0 2.8e-05 23.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EEB08391.1 - 0.032 13.6 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GxGYxYP_C PF14323.6 EEB08391.1 - 0.063 13.1 0.0 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain tRNA-synt_1_2 PF13603.6 EEB08391.1 - 0.083 12.4 0.1 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-TFIIIC PF12660.7 EEB08392.1 - 1.6e-17 63.3 2.6 3.7e-17 62.1 2.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 EEB08392.1 - 4.4e-06 26.8 3.8 1.8e-05 24.7 1.7 3.0 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-ribbon_3 PF13248.6 EEB08392.1 - 0.023 14.1 3.3 0.8 9.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain PHF5 PF03660.14 EEB08392.1 - 0.44 10.8 2.8 0.59 10.4 0.7 2.2 2 0 0 2 2 2 0 PHF5-like protein RRM_1 PF00076.22 EEB08393.1 - 7.5e-09 35.3 0.2 1.9e-08 34.0 0.2 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB08393.1 - 4e-05 23.2 0.1 4.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEB08393.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 Methyltransf_25 PF13649.6 EEB08394.1 - 1.4e-13 51.3 0.1 8.7e-13 48.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EEB08394.1 - 9.3e-12 44.9 0.2 9.3e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EEB08394.1 - 2.4e-11 44.1 0.1 8.2e-11 42.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08394.1 - 3.1e-10 40.0 1.7 6.7e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EEB08394.1 - 1.3e-06 28.1 0.1 2.7e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EEB08394.1 - 7.3e-06 25.9 0.0 2.1e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EEB08394.1 - 1.7e-05 24.8 0.1 4.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08394.1 - 0.00016 22.4 0.1 0.00069 20.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain zf-C2H2_2 PF12756.7 EEB08394.1 - 0.00022 21.5 0.9 0.00071 19.9 0.7 1.9 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_9 PF08003.11 EEB08394.1 - 0.00036 19.6 0.4 0.00081 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Phage_Mu_Gam PF07352.12 EEB08394.1 - 0.0012 18.7 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Ubie_methyltran PF01209.18 EEB08394.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-C2H2_3rep PF18868.1 EEB08394.1 - 0.0017 19.1 0.2 0.0017 19.1 0.2 2.5 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 EEB08394.1 - 0.0027 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type Methyltransf_16 PF10294.9 EEB08394.1 - 0.0035 17.1 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 EEB08394.1 - 0.0086 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 EEB08394.1 - 0.0089 15.6 0.1 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase zf-C2H2_4 PF13894.6 EEB08394.1 - 0.027 15.3 0.7 0.085 13.7 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_32 PF13679.6 EEB08394.1 - 0.035 14.1 0.9 0.09 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PRMT5 PF05185.16 EEB08394.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase UPF0020 PF01170.18 EEB08394.1 - 0.086 12.5 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EEB08394.1 - 0.11 12.2 0.6 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 zf-Di19 PF05605.12 EEB08394.1 - 0.2 12.0 0.3 0.56 10.5 0.3 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cnn_1N PF07989.11 EEB08394.1 - 0.41 10.8 6.3 0.88 9.8 6.3 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF5320 PF17253.2 EEB08394.1 - 0.96 10.6 2.4 2.4 9.3 2.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4407 PF14362.6 EEB08394.1 - 1 8.7 5.5 1.7 7.9 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RE_Bpu10I PF09549.10 EEB08395.1 - 0.022 14.4 0.3 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Bpu10I restriction endonuclease DUF4615 PF15393.6 EEB08395.1 - 0.027 15.0 0.2 0.032 14.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Prefoldin_2 PF01920.20 EEB08395.1 - 0.033 14.1 1.4 0.056 13.4 1.4 1.4 1 1 0 1 1 1 0 Prefoldin subunit Transcrip_reg PF01709.20 EEB08396.1 - 3.7e-69 232.8 5.3 4.2e-69 232.6 5.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator SHQ1 PF04925.15 EEB08397.1 - 5.9e-65 218.1 1.5 8e-65 217.7 1.5 1.2 1 0 0 1 1 1 1 SHQ1 protein SNARE PF05739.19 EEB08398.1 - 2.6e-11 43.3 0.1 9.9e-11 41.5 0.1 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EEB08398.1 - 8.8e-06 24.8 1.8 1.9e-05 23.7 0.5 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-6_N PF09177.11 EEB08398.1 - 0.00013 22.5 6.1 0.0025 18.3 2.3 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Syntaxin PF00804.25 EEB08398.1 - 0.00013 21.7 11.1 0.044 13.5 0.0 2.7 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 EEB08398.1 - 0.00047 20.3 0.6 0.00047 20.3 0.6 2.8 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 EEB08398.1 - 0.17 12.2 6.4 0.42 11.0 0.2 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.9 EEB08398.1 - 0.21 11.0 12.9 0.024 14.1 5.2 2.1 1 1 0 2 2 2 0 Clusterin-associated protein-1 DUF16 PF01519.16 EEB08398.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EEB08398.1 - 0.5 10.4 6.7 3.1 7.9 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EEB08398.1 - 0.72 9.1 14.8 0.53 9.5 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EEB08398.1 - 2.3 8.4 17.1 1.4 9.1 0.4 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 EEB08398.1 - 2.6 8.3 9.4 18 5.6 9.3 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein FlaC_arch PF05377.11 EEB08398.1 - 4.4 7.8 6.6 2.2 8.7 0.1 3.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) LIAS_N PF16881.5 EEB08399.2 - 1.6e-35 121.7 0.0 3.2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EEB08399.2 - 1.3e-14 55.0 0.0 2.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Methyltrn_RNA_3 PF02598.17 EEB08400.1 - 2.9e-48 164.9 0.0 3.5e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Glyco_transf_34 PF05637.12 EEB08401.1 - 1e-64 218.5 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family AdoHcyase PF05221.17 EEB08402.1 - 1.2e-135 451.5 0.0 7.5e-75 251.8 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EEB08402.1 - 1.9e-85 284.9 3.1 2.9e-85 284.3 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEB08402.1 - 2.8e-07 30.1 0.1 4.9e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EEB08402.1 - 2.6e-05 23.8 0.1 4.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EEB08402.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 EEB08403.2 - 2.5e-56 191.0 0.0 4.1e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08403.2 - 6.4e-33 114.1 0.0 9.9e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEB08403.2 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB08403.2 - 0.038 12.8 0.0 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EEB08403.2 - 0.075 12.9 0.0 1.1 9.1 0.0 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EEB08404.1 - 9.7e-07 29.4 11.8 0.0016 19.2 0.1 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat SRA1 PF07304.11 EEB08404.1 - 9e-06 25.5 0.0 9e-06 25.5 0.0 2.7 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EEB08404.1 - 0.00012 21.9 0.2 0.00045 20.0 0.2 1.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 EEB08404.1 - 0.0016 18.5 0.1 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Prp18 domain ANAPC4_WD40 PF12894.7 EEB08404.1 - 0.0081 16.4 0.5 0.93 9.8 0.4 3.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NIF PF03031.18 EEB08405.1 - 1.1e-44 152.0 0.0 1.7e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Thrombin_light PF09396.10 EEB08405.1 - 0.023 14.4 0.1 0.37 10.6 0.1 2.4 2 0 0 2 2 2 0 Thrombin light chain ANAPC10 PF03256.16 EEB08406.1 - 2.7e-63 213.0 0.1 3.1e-63 212.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EEB08406.1 - 0.078 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 F5/8 type C domain Iso_dh PF00180.20 EEB08407.1 - 3.5e-125 417.8 0.0 4.2e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tam41_Mmp37 PF09139.11 EEB08408.1 - 2e-111 372.5 0.5 2.3e-111 372.3 0.5 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial HALZ PF02183.18 EEB08409.1 - 0.0027 17.9 4.1 0.092 13.0 0.3 3.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper KASH_CCD PF14662.6 EEB08409.1 - 0.034 14.0 21.3 0.082 12.7 9.7 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EEB08409.1 - 0.057 13.5 8.9 0.98 9.6 0.3 3.7 3 0 0 3 3 3 0 bZIP transcription factor ATG16 PF08614.11 EEB08409.1 - 0.33 11.2 32.8 0.029 14.6 18.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EEB08409.1 - 1 9.4 11.1 2.1 8.4 2.7 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EEB08409.1 - 1.1 9.1 14.3 5.8 6.8 1.0 3.9 3 1 0 3 3 3 0 Septum formation initiator JIP_LZII PF16471.5 EEB08409.1 - 2.6 8.3 13.1 1.3 9.3 1.8 3.4 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4094 PF13334.6 EEB08409.1 - 3.5 8.1 6.9 3 8.3 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) LPP PF04728.13 EEB08409.1 - 4.5 7.7 21.9 2.4 8.6 1.7 5.2 5 1 1 6 6 4 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 EEB08409.1 - 4.6 7.3 24.0 1.8 8.6 1.5 3.8 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Troponin PF00992.20 EEB08409.1 - 5.8 7.2 13.5 1.5 9.2 8.7 2.4 1 1 1 2 2 2 0 Troponin DUF3450 PF11932.8 EEB08409.1 - 6.7 5.9 24.4 3.9 6.7 14.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) CT_C_D PF02682.16 EEB08409.1 - 7.6 6.2 6.3 2.2 8.0 0.5 2.4 1 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D DUF1664 PF07889.12 EEB08409.1 - 8.5 6.4 20.0 2.6 8.1 0.7 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EEB08409.1 - 8.6 4.2 16.3 0.77 7.6 10.3 2.1 1 1 1 2 2 2 0 Prominin DNA_topoisoIV PF00521.20 EEB08411.1 - 5.7e-127 424.1 0.2 9.6e-127 423.4 0.2 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EEB08411.1 - 7.7e-49 165.2 0.5 7.7e-49 165.2 0.5 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EEB08411.1 - 6.2e-24 84.4 0.3 1.6e-23 83.1 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EEB08411.1 - 7.3e-14 52.2 0.0 1.7e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EEB08411.1 - 3.2e-09 37.0 0.0 1.5e-08 34.8 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Ribosom_S12_S23 PF00164.25 EEB08412.1 - 1.3e-49 166.6 0.8 1.6e-49 166.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Sof1 PF04158.14 EEB08413.1 - 2.2e-29 101.5 15.8 3.5e-29 100.9 15.8 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EEB08413.1 - 1.4e-25 89.1 10.6 6.7e-07 29.9 0.0 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08413.1 - 1.3e-07 31.8 0.3 0.005 17.1 0.0 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB08413.1 - 0.00023 21.1 0.3 0.0012 18.8 0.2 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Eisosome1 PF12757.7 EEB08413.1 - 0.0085 16.4 5.3 0.015 15.5 5.3 1.3 1 0 0 1 1 1 1 Eisosome protein 1 Ge1_WD40 PF16529.5 EEB08413.1 - 0.033 13.1 0.1 0.81 8.6 0.0 2.8 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cpn60_TCP1 PF00118.24 EEB08414.1 - 2.1e-168 561.0 0.5 2.4e-168 560.8 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dict-STAT-coil PF09267.10 EEB08415.2 - 0.013 15.8 2.6 0.013 15.8 2.6 2.1 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil YgbB PF02542.16 EEB08415.2 - 0.049 13.9 0.5 0.095 13.0 0.2 1.5 1 1 1 2 2 2 0 YgbB family APG6_N PF17675.1 EEB08415.2 - 0.088 13.3 6.4 0.17 12.4 0.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 EEB08415.2 - 0.59 10.4 6.7 0.09 13.1 2.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein GIT_CC PF16559.5 EEB08415.2 - 3.4 7.6 12.4 7.5 6.5 0.2 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TruD PF01142.18 EEB08416.1 - 5.8e-73 246.1 0.0 2.7e-70 237.3 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Med14 PF08638.11 EEB08417.1 - 7.9e-57 191.8 0.0 1.4e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkr1 PF08636.10 EEB08418.1 - 1.4e-24 86.0 4.2 1.6e-24 85.8 4.2 1.0 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.6 EEB08418.1 - 0.013 15.2 1.2 0.015 14.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) GPI2 PF06432.11 EEB08418.1 - 0.019 14.4 0.1 0.019 14.4 0.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase TraG_N PF07916.11 EEB08418.1 - 0.069 12.0 0.1 0.077 11.8 0.1 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region UL45 PF05473.12 EEB08418.1 - 0.079 12.6 1.9 0.11 12.2 1.9 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF5325 PF17259.2 EEB08418.1 - 0.12 12.2 0.7 0.18 11.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5325) DUF4133 PF13571.6 EEB08418.1 - 0.93 9.9 2.9 1.3 9.4 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Complex1_LYR_2 PF13233.6 EEB08419.1 - 1.2e-18 67.6 1.4 2.4e-18 66.6 1.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EEB08419.1 - 2.7e-11 43.3 0.3 1.9e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) ANAPC2 PF08672.11 EEB08420.1 - 5.7e-25 87.6 0.6 4.3e-24 84.8 0.1 2.7 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EEB08420.1 - 7.5e-23 81.0 2.4 5.9e-21 74.7 0.6 2.2 2 0 0 2 2 2 2 Cullin family Flg_hook PF02120.16 EEB08420.1 - 0.02 14.8 0.9 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK SWI-SNF_Ssr4 PF08549.10 EEB08421.2 - 2.4e-35 122.4 44.0 4.9e-19 68.5 10.4 4.1 1 1 3 4 4 4 2 Fungal domain of unknown function (DUF1750) TnpV PF14198.6 EEB08421.2 - 4.8 7.2 6.8 0.29 11.1 1.2 1.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Mito_carr PF00153.27 EEB08422.1 - 1.2e-54 182.2 0.2 1.2e-16 60.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb2_6 PF00562.28 EEB08423.1 - 2.1e-115 385.9 0.0 5.5e-115 384.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEB08423.1 - 7.2e-39 133.4 0.0 1.1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EEB08423.1 - 2.9e-28 97.8 0.0 7.7e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EEB08423.1 - 1e-22 79.9 0.0 2.3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EEB08423.1 - 3.5e-22 79.0 0.0 5.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EEB08423.1 - 1.8e-16 60.3 1.0 5.8e-15 55.5 1.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Actin PF00022.19 EEB08424.1 - 5.2e-133 443.6 0.0 5.9e-133 443.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEB08424.1 - 8.4e-08 31.4 0.0 9.2e-05 21.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DAHP_synth_1 PF00793.20 EEB08425.1 - 3.2e-103 344.4 0.0 4e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AbiEi_1 PF09407.10 EEB08425.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain RhoGEF PF00621.20 EEB08426.1 - 2e-28 99.9 0.0 3.4e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain MA3 PF02847.17 EEB08428.1 - 3.7e-27 94.6 0.1 3.6e-26 91.4 0.0 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EEB08428.1 - 6.2e-27 94.6 1.3 6.2e-27 94.6 1.3 2.6 3 0 0 3 3 3 1 MIF4G domain Ub-RnfH PF03658.14 EEB08428.1 - 0.07 13.5 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 RnfH family Ubiquitin Ribosomal_S2 PF00318.20 EEB08429.1 - 6e-69 231.6 1.0 7.6e-42 143.0 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 tRNA-synt_2b PF00587.25 EEB08430.1 - 2.8e-33 115.4 0.0 7.3e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEB08430.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_M20 PF01546.28 EEB08431.1 - 1.9e-32 112.6 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEB08431.1 - 7.6e-08 32.3 0.0 2.4e-07 30.6 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEB08431.1 - 3.4e-06 26.9 0.0 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Glucan_synthase PF02364.15 EEB08432.1 - 0 1350.1 0.0 0 1349.4 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEB08432.1 - 6.4e-39 133.2 2.5 2.1e-38 131.6 1.2 2.6 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aconitase PF00330.20 EEB08433.2 - 3.5e-150 501.0 0.0 4.4e-150 500.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEB08433.2 - 1.2e-43 148.6 0.0 2.1e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CBS PF00571.28 EEB08434.1 - 4.5e-25 87.9 2.3 4.3e-06 27.1 0.0 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 EEB08434.1 - 2e-09 37.3 0.0 4.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain AAA_22 PF13401.6 EEB08434.1 - 0.14 12.4 0.4 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain Med9 PF07544.13 EEB08435.1 - 0.0028 17.7 0.5 0.0034 17.4 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Cyclin PF08613.11 EEB08436.1 - 4.1e-06 27.3 0.1 9e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EEB08436.1 - 0.17 11.7 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pkinase PF00069.25 EEB08437.1 - 1.4e-60 205.0 0.0 4.4e-60 203.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08437.1 - 2.5e-37 128.6 0.0 6.3e-25 87.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB08437.1 - 0.00029 20.3 0.3 0.00075 18.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB08437.1 - 0.0029 16.4 0.0 0.0082 15.0 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB08437.1 - 0.085 12.8 0.4 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family GrpE PF01025.19 EEB08437.1 - 0.18 11.4 6.1 0.36 10.5 6.1 1.4 1 0 0 1 1 1 0 GrpE DUF4200 PF13863.6 EEB08437.1 - 0.21 12.0 15.8 0.11 12.9 12.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FAM76 PF16046.5 EEB08437.1 - 4.6 6.5 7.1 9.9 5.4 7.1 1.5 1 0 0 1 1 1 0 FAM76 protein FdhE PF04216.12 EEB08437.1 - 8.5 6.2 10.8 1.9 8.3 6.6 1.8 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Nup35_RRM PF05172.13 EEB08438.2 - 1.8e-25 88.9 0.2 7.4e-25 86.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EEB08438.2 - 3.4e-05 23.8 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Suf PF05843.14 EEB08439.1 - 1.9e-79 267.8 0.1 2.5e-76 257.5 0.0 3.7 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 EEB08439.1 - 0.00015 21.0 0.0 12 4.9 0.0 4.2 2 1 2 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EEB08439.1 - 0.004 17.9 9.6 12 7.1 0.2 6.5 5 2 3 8 8 8 1 Tetratricopeptide repeat Sugar_tr PF00083.24 EEB08440.1 - 5.4e-105 351.9 26.1 6.3e-105 351.6 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB08440.1 - 1.6e-24 86.5 40.3 3e-24 85.6 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PT-VENN PF04829.13 EEB08440.1 - 0.49 10.5 3.6 1.8 8.7 0.2 2.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SH3_1 PF00018.28 EEB08441.2 - 3.6e-15 55.3 0.0 7.6e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB08441.2 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB08441.2 - 1.6e-10 40.5 0.0 3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 EEB08441.2 - 6.2e-10 39.2 0.1 3.1e-09 37.0 0.1 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RPA_interact_M PF14767.6 EEB08441.2 - 0.16 12.5 0.8 0.67 10.6 0.8 2.1 1 0 0 1 1 1 0 Replication protein A interacting middle Not1 PF04054.15 EEB08442.1 - 1.7e-117 392.5 8.8 1.9e-116 389.0 4.4 3.0 1 1 1 2 2 2 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EEB08442.1 - 1.7e-83 279.4 8.1 5.4e-82 274.5 5.6 2.6 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EEB08442.1 - 7.2e-50 168.8 0.3 1.9e-49 167.4 0.3 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EEB08442.1 - 2.5e-37 128.1 7.1 2.5e-37 128.1 7.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EEB08442.1 - 1e-25 90.6 3.1 2.8e-25 89.1 3.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Rad33 PF08730.10 EEB08442.1 - 0.13 12.3 5.2 1.3 9.0 0.0 4.2 4 1 1 5 5 5 0 Rad33 ERG2_Sigma1R PF04622.12 EEB08443.1 - 2.3e-87 291.7 0.0 2.7e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EMP24_GP25L PF01105.24 EEB08443.1 - 0.24 11.3 1.1 0.35 10.8 1.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sgf11 PF08209.11 EEB08444.2 - 2.5e-15 55.7 1.1 2.5e-15 55.7 1.1 2.3 2 1 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 EEB08444.2 - 0.0028 17.5 0.4 0.0028 17.5 0.4 1.5 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain zf_C2H2_13 PF18508.1 EEB08444.2 - 0.031 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-C2HC_2 PF13913.6 EEB08444.2 - 0.091 12.7 0.4 0.091 12.7 0.4 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 EEB08444.2 - 0.43 10.7 9.2 1 9.5 2.0 2.7 1 1 2 3 3 3 0 Zinc ribbon domain RhoGEF PF00621.20 EEB08445.1 - 3.8e-11 43.6 6.0 4.7e-10 40.0 6.0 2.3 1 1 0 1 1 1 1 RhoGEF domain Pro_isomerase PF00160.21 EEB08446.1 - 1.9e-54 184.2 0.0 2.1e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 EEB08447.1 - 8.6e-65 218.7 0.0 1.4e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08447.1 - 1.4e-32 113.0 0.0 2.5e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EEB08447.1 - 4.7e-27 94.0 0.1 8.8e-27 93.2 0.1 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EEB08447.1 - 6.7e-08 32.2 0.0 5.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEB08447.1 - 0.00012 22.1 0.1 0.0014 18.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Toxin_37 PF11415.8 EEB08447.1 - 0.037 13.9 0.4 0.037 13.9 0.4 1.7 2 0 0 2 2 2 0 Antifungal peptide termicin Haspin_kinase PF12330.8 EEB08447.1 - 0.05 12.5 0.8 0.078 11.9 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 EEB08447.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EEB08447.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.19 EEB08448.1 - 9.4e-24 83.6 3.3 1.5e-23 82.9 3.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEB08448.1 - 1.7e-17 63.8 2.5 2.9e-17 63.0 2.5 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EEB08448.1 - 0.015 15.8 0.1 0.015 15.8 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Abhydrolase_1 PF00561.20 EEB08449.1 - 1.6e-26 93.5 0.0 2.9e-23 82.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEB08449.1 - 8.5e-20 71.0 0.6 2e-19 69.8 0.6 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEB08449.1 - 1e-19 72.0 0.0 1.3e-19 71.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EEB08449.1 - 1.7e-06 28.3 0.2 1.6e-05 25.2 0.2 2.3 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EEB08449.1 - 2.7e-06 27.4 0.1 3.5e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Serine hydrolase DUF1100 PF06500.11 EEB08449.1 - 0.00019 20.4 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.10 EEB08449.1 - 0.00026 21.0 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein LIDHydrolase PF10230.9 EEB08449.1 - 0.004 16.8 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EEB08449.1 - 0.0043 16.8 0.0 0.27 10.9 0.1 2.9 3 0 0 3 3 3 1 PGAP1-like protein FSH1 PF03959.13 EEB08449.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EEB08449.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EEB08449.1 - 0.046 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EEB08449.1 - 0.06 12.8 0.1 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF915 PF06028.11 EEB08449.1 - 0.12 11.6 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 EEB08449.1 - 0.18 11.6 2.5 19 5.0 0.1 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Sugar_tr PF00083.24 EEB08451.1 - 1.7e-124 416.1 22.0 2e-124 415.9 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB08451.1 - 2.1e-22 79.5 27.8 2.4e-18 66.2 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EEB08451.1 - 0.011 14.2 3.4 0.017 13.5 3.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector PRA1 PF03208.19 EEB08451.1 - 2.7 7.6 5.8 0.78 9.4 0.9 2.6 2 1 0 2 2 2 0 PRA1 family protein Sugar_tr PF00083.24 EEB08453.1 - 2.4e-114 382.7 20.3 2.8e-114 382.5 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB08453.1 - 4.4e-20 71.9 27.5 6e-15 55.0 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EEB08453.1 - 0.0055 15.2 4.8 0.0079 14.6 4.8 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector DAGAT PF03982.13 EEB08454.1 - 4.5e-74 249.0 0.1 4.4e-44 150.6 0.0 2.0 1 1 1 2 2 2 2 Diacylglycerol acyltransferase DUF2852 PF11014.8 EEB08454.1 - 0.17 12.0 2.9 0.4 10.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Prominin PF05478.11 EEB08454.1 - 0.44 8.4 0.6 0.88 7.4 0.0 1.7 2 0 0 2 2 2 0 Prominin RAMP4 PF06624.12 EEB08456.1 - 7.3e-09 35.6 0.8 8.2e-09 35.4 0.8 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF5321 PF17254.2 EEB08456.1 - 0.022 14.2 0.1 0.026 13.9 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5321) StbA PF06406.11 EEB08456.1 - 0.029 13.6 0.1 0.031 13.5 0.1 1.0 1 0 0 1 1 1 0 StbA protein DUF5056 PF16479.5 EEB08456.1 - 0.051 13.8 0.0 0.054 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF4366 PF14283.6 EEB08456.1 - 0.063 13.3 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zf_RING PF16744.5 EEB08456.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 KIAA1045 RING finger P120R PF08062.11 EEB08456.1 - 0.54 10.7 2.6 2.3 8.7 0.1 2.6 2 1 0 2 2 2 0 P120R (NUC006) repeat LRR_4 PF12799.7 EEB08457.1 - 5.2e-06 26.7 15.0 1.9 9.0 0.0 6.8 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) Spt5_N PF11942.8 EEB08457.1 - 0.66 11.0 7.7 6.3 7.9 7.5 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal LRR_1 PF00560.33 EEB08457.1 - 2.7 8.9 12.8 1.8e+02 3.3 0.0 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat SNF2_N PF00176.23 EEB08458.1 - 2.4e-52 177.8 0.1 4.1e-51 173.8 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB08458.1 - 2e-13 50.7 0.0 7.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08458.1 - 2.2e-06 27.8 0.1 1.3e-05 25.3 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EEB08458.1 - 3.8e-06 26.7 12.3 3.8e-06 26.7 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB08458.1 - 0.0011 19.2 11.8 0.0011 19.2 11.8 2.5 2 0 0 2 2 2 1 Ring finger domain DEAD PF00270.29 EEB08458.1 - 0.0013 18.6 0.1 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 EEB08458.1 - 0.0023 17.9 7.0 0.0023 17.9 7.0 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEB08458.1 - 0.0026 17.6 8.9 0.0026 17.6 8.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB08458.1 - 0.0047 17.1 11.5 0.0047 17.1 11.5 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EEB08458.1 - 0.012 15.5 10.3 0.012 15.5 10.3 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IF-2B PF01008.17 EEB08459.1 - 5.2e-71 239.1 0.6 6.1e-71 238.9 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF5618 PF18498.1 EEB08459.1 - 0.054 13.7 0.2 0.095 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5618) zf-RING_2 PF13639.6 EEB08460.1 - 2.7e-09 37.2 10.9 2.7e-09 37.2 10.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEB08460.1 - 2.1e-08 33.9 7.0 2.1e-08 33.9 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB08460.1 - 2.4e-08 33.7 10.7 2.4e-08 33.7 10.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB08460.1 - 3.9e-08 33.0 10.5 3.9e-08 33.0 10.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB08460.1 - 8.1e-08 32.2 9.1 8.1e-08 32.2 9.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EEB08460.1 - 7.4e-07 29.2 10.4 7.4e-07 29.2 10.4 2.6 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EEB08460.1 - 8.2e-06 25.7 10.9 8.2e-06 25.7 10.9 2.3 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEB08460.1 - 0.00026 20.8 7.6 0.00026 20.8 7.6 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EEB08460.1 - 0.0012 18.8 1.2 0.0032 17.5 1.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEB08460.1 - 0.0013 19.0 10.9 0.0013 19.0 10.9 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EEB08460.1 - 0.0033 17.2 3.7 0.0063 16.3 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EEB08460.1 - 0.026 14.6 6.3 0.026 14.6 6.3 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 EEB08460.1 - 0.047 13.7 12.7 0.9 9.6 5.1 2.4 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 EEB08460.1 - 0.05 13.6 15.3 1.3 9.1 0.6 3.0 2 1 2 4 4 4 0 Double zinc ribbon Urm1 PF09138.11 EEB08461.1 - 9.2e-31 106.1 0.7 1.1e-30 105.8 0.7 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EEB08461.1 - 7.1e-07 29.8 0.1 9.6e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 ThiS family RRP7 PF12923.7 EEB08462.1 - 2e-33 115.0 8.6 3e-33 114.5 8.6 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EEB08462.1 - 0.00085 19.2 0.5 0.029 14.2 0.0 2.6 1 1 1 2 2 2 1 Rrp7 RRM-like N-terminal domain Occludin_ELL PF07303.13 EEB08462.1 - 0.025 15.3 3.3 0.34 11.6 0.1 2.4 2 0 0 2 2 2 0 Occludin homology domain MetOD2 PF18548.1 EEB08462.1 - 0.09 12.9 4.0 0.27 11.4 1.6 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 MAT1 PF06391.13 EEB08463.2 - 4.7e-53 180.1 18.0 6.8e-53 179.5 18.0 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EEB08463.2 - 8.2e-30 102.5 8.5 1.3e-29 101.8 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEB08463.2 - 0.00035 20.1 0.5 0.00061 19.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EEB08463.2 - 0.0012 19.1 6.7 0.0021 18.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB08463.2 - 0.0017 18.1 5.4 0.004 17.0 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEB08463.2 - 0.0043 16.9 4.6 0.0078 16.1 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB08463.2 - 0.0066 16.3 8.4 0.034 14.0 8.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PPL4 PF18188.1 EEB08463.2 - 0.012 15.5 0.5 0.021 14.8 0.5 1.3 1 0 0 1 1 1 0 Prim-pol 4 DUF3797 PF12677.7 EEB08463.2 - 0.023 14.6 2.1 0.055 13.4 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 EEB08463.2 - 0.061 13.3 1.2 0.061 13.3 1.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Mit_KHE1 PF10173.9 EEB08463.2 - 0.34 11.0 3.7 0.78 9.8 3.7 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related XOO_2897-deam PF14440.6 EEB08463.2 - 0.41 10.8 4.2 0.89 9.7 0.7 2.5 2 1 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase VIT1 PF01988.19 EEB08463.2 - 0.47 10.3 1.0 0.76 9.6 1.0 1.3 1 0 0 1 1 1 0 VIT family PhnA_Zn_Ribbon PF08274.12 EEB08463.2 - 5.3 7.1 6.4 0.21 11.5 0.4 1.7 2 0 0 2 2 1 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.6 EEB08463.2 - 5.4 6.9 11.0 18 5.2 10.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TLD PF07534.16 EEB08465.1 - 2.7e-21 76.3 1.2 3.4e-19 69.4 1.2 2.5 1 1 0 1 1 1 1 TLD EVE PF01878.18 EEB08466.1 - 1e-41 142.3 0.1 1.6e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 EVE domain Coleoptericin PF06286.11 EEB08466.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Coleoptericin Med8 PF10232.9 EEB08467.2 - 2e-19 70.1 6.2 2.6e-19 69.8 6.2 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Kelch_6 PF13964.6 EEB08468.1 - 1e-21 76.4 2.9 1.4e-07 31.5 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EEB08468.1 - 7.3e-16 57.5 5.1 5e-05 22.8 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EEB08468.1 - 1.6e-15 57.0 2.1 7.4e-06 26.1 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EEB08468.1 - 9.3e-15 54.2 0.4 2.2e-05 24.3 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EEB08468.1 - 1.1e-11 44.2 3.7 0.0013 18.6 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EEB08468.1 - 1.4e-11 44.2 1.6 5.6e-06 26.3 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain DCP1 PF06058.13 EEB08468.1 - 0.13 12.2 0.5 0.63 10.0 0.1 2.3 2 0 0 2 2 2 0 Dcp1-like decapping family Ssu72 PF04722.13 EEB08469.1 - 1.3e-87 292.3 0.0 1.5e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 EEB08470.1 - 1.7e-18 65.9 3.5 1.1e-11 44.1 0.6 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT BCAS2 PF05700.11 EEB08470.1 - 0.0052 16.5 7.1 0.0052 16.5 7.1 2.6 1 1 1 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) Csm1_N PF18504.1 EEB08470.1 - 0.019 15.3 6.4 0.019 15.3 6.4 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain XRN_M PF17846.1 EEB08470.1 - 0.05 12.6 10.6 0.11 11.5 10.6 1.5 1 0 0 1 1 1 0 Xrn1 helical domain Lebercilin PF15619.6 EEB08470.1 - 0.17 11.5 27.5 0.16 11.7 11.8 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TFIIA PF03153.13 EEB08470.1 - 0.38 10.7 15.1 0.57 10.1 15.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Alanine_zipper PF11839.8 EEB08470.1 - 2.3 8.6 10.2 8.4 6.8 0.7 3.1 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein GIT_CC PF16559.5 EEB08470.1 - 2.9 7.8 13.4 8.6 6.3 2.7 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DHR10 PF18595.1 EEB08470.1 - 4.6 7.3 31.7 0.71 9.9 18.0 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ZapB PF06005.12 EEB08470.1 - 5.9 7.4 25.5 0.84 10.1 12.2 3.6 1 1 1 3 3 3 0 Cell division protein ZapB tRNA-synt_2d PF01409.20 EEB08471.1 - 1.5e-87 293.2 0.0 2.2e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EEB08471.1 - 7.5e-16 58.2 0.9 2.2e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EEB08471.1 - 6e-08 32.4 0.0 8.9e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EEB08471.1 - 0.00017 20.8 1.4 0.0023 17.1 0.0 3.0 3 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 EEB08471.1 - 0.00081 19.3 7.6 0.0018 18.2 7.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 EEB08471.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HTH_45 PF14947.6 EEB08471.1 - 0.14 12.1 0.3 2.5 8.1 0.1 2.6 2 1 1 3 3 3 0 Winged helix-turn-helix Hist_deacetyl PF00850.19 EEB08472.1 - 2.9e-83 279.9 0.0 3.4e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EEB08473.1 - 1.6e-21 76.8 3.1 2.2e-21 76.3 3.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEB08473.1 - 7e-07 29.0 8.6 1.1e-06 28.4 8.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEB08473.1 - 0.0013 18.3 2.0 0.0031 17.0 2.0 1.7 1 0 0 1 1 1 1 PHD-finger OmpH PF03938.14 EEB08473.1 - 0.048 14.0 2.0 0.069 13.5 2.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Moricin PF06451.11 EEB08473.1 - 0.06 13.1 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Moricin Mic1 PF07035.12 EEB08473.1 - 0.089 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like zf-HC5HC2H PF13771.6 EEB08473.1 - 0.17 12.2 5.2 0.52 10.6 5.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain EIF_2_alpha PF07541.12 EEB08474.1 - 3.7e-39 133.4 0.1 8.4e-39 132.3 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EEB08474.1 - 4.4e-12 46.2 3.0 9.6e-12 45.1 3.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SET PF00856.28 EEB08475.1 - 2.3e-15 57.4 0.0 5.8e-14 52.8 0.0 2.3 1 1 0 1 1 1 1 SET domain APH PF01636.23 EEB08475.1 - 0.044 13.7 0.2 0.066 13.1 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAF PF08666.12 EEB08475.1 - 0.17 12.5 0.0 20 5.9 0.0 2.3 2 0 0 2 2 2 0 SAF domain Metallophos PF00149.28 EEB08476.1 - 6.6e-36 124.7 1.0 1e-35 124.1 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAM_decarbox PF01536.16 EEB08477.1 - 1.3e-118 396.1 0.0 1.5e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase 60KD_IMP PF02096.20 EEB08478.1 - 4.9e-25 88.4 0.4 8.2e-25 87.6 0.4 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Hid1 PF12722.7 EEB08479.1 - 2.1e-54 185.0 20.3 2.1e-54 185.0 20.3 1.6 1 1 1 2 2 2 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EEB08479.1 - 7.1e-18 64.4 17.6 9.2e-18 64.0 17.6 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein PLU-1 PF08429.11 EEB08480.1 - 7.3e-80 268.7 11.9 1.1e-77 261.5 10.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein PHD PF00628.29 EEB08480.1 - 1.8e-25 88.6 37.7 6e-11 42.1 6.8 4.0 3 0 0 3 3 3 3 PHD-finger JmjC PF02373.22 EEB08480.1 - 2.7e-11 43.9 0.1 8.3e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 EEB08480.1 - 9.3e-09 35.8 0.1 5.1e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-PHD-like PF15446.6 EEB08480.1 - 0.0019 17.9 16.3 0.16 11.6 0.4 4.0 3 0 0 3 3 3 3 PHD/FYVE-zinc-finger like domain TFIIF_alpha PF05793.12 EEB08480.1 - 4.8 5.6 5.7 13 4.3 5.7 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PHD_2 PF13831.6 EEB08480.1 - 6.2 6.5 31.4 0.24 11.0 0.9 4.1 4 0 0 4 4 4 0 PHD-finger Ribosomal_L27 PF01016.19 EEB08481.1 - 6.7e-34 115.7 1.5 8.3e-34 115.5 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein MOR2-PAG1_N PF14222.6 EEB08482.1 - 2.3e-80 271.1 12.4 5.8e-79 266.5 12.4 2.5 1 1 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EEB08482.1 - 1.2e-41 143.3 10.0 2.9e-29 102.7 0.0 4.3 4 1 1 5 5 5 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EEB08482.1 - 8.6e-23 80.0 5.2 1.4e-09 36.2 0.1 3.2 3 0 0 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 EEB08482.1 - 0.0099 16.1 0.1 15 6.1 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat RPN1_RPN2_N PF17781.1 EEB08483.1 - 8.1e-120 399.9 1.7 1.2e-119 399.3 1.0 1.6 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EEB08483.1 - 2.4e-27 94.0 23.4 2.9e-05 24.3 0.0 9.1 11 0 0 11 11 11 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 EEB08483.1 - 1.2e-22 79.7 0.2 1.2e-22 79.7 0.2 1.8 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 EEB08483.1 - 0.0023 18.3 0.1 1.2 9.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats MCM_bind PF09739.9 EEB08483.1 - 0.0066 15.0 4.7 0.0092 14.5 4.7 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Tom22 PF04281.13 EEB08483.1 - 1.7 8.4 5.7 4 7.2 5.7 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 ECH_2 PF16113.5 EEB08484.1 - 0.17 11.3 0.6 0.26 10.7 0.6 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ANKH PF07260.11 EEB08484.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) GlutR_dimer PF00745.20 EEB08484.1 - 0.19 12.2 0.8 0.66 10.5 0.3 2.1 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain GCV_H PF01597.19 EEB08486.1 - 6.1e-45 152.0 0.4 8.1e-45 151.6 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EEB08486.1 - 0.00089 19.2 0.3 0.0014 18.5 0.3 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EEB08486.1 - 0.0013 18.5 0.4 0.0035 17.1 0.2 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Arrestin_C PF02752.22 EEB08487.1 - 3.5e-18 66.4 0.1 2.6e-17 63.5 0.0 2.5 4 0 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEB08487.1 - 1.2e-09 38.4 0.0 6.6e-08 32.7 0.0 2.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.24 EEB08488.1 - 2e-30 106.0 39.7 1.7e-21 76.6 12.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEB08488.1 - 1.5e-18 66.8 44.0 3.2e-16 59.2 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SRI PF08236.11 EEB08489.1 - 0.054 13.7 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Cellulase PF00150.18 EEB08490.1 - 2.5e-05 23.8 0.1 3.7e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HTH_21 PF13276.6 EEB08490.1 - 0.046 13.8 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 HTH-like domain zf-C2H2 PF00096.26 EEB08491.1 - 0.0074 16.7 1.6 0.0074 16.7 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB08491.1 - 0.21 12.5 0.9 0.85 10.6 0.9 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_S24 PF00717.23 EEB08492.1 - 1.8e-07 31.0 0.0 5.1e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEB08492.1 - 1.7e-06 27.9 0.0 0.00085 19.1 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Ribosomal_L4 PF00573.22 EEB08493.1 - 7.2e-44 149.8 0.0 8.8e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Mito_carr PF00153.27 EEB08494.1 - 9.9e-61 201.7 3.2 1.2e-21 76.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3357 PF11837.8 EEB08494.1 - 0.017 15.6 0.5 0.038 14.4 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) CbiM PF01891.16 EEB08494.1 - 0.044 13.6 0.1 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region F-box PF00646.33 EEB08495.1 - 1.4e-06 28.0 0.4 3.5e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEB08495.1 - 1.8e-06 27.7 2.0 3e-06 27.0 0.8 1.9 2 0 0 2 2 2 1 F-box-like MIT PF04212.18 EEB08495.1 - 0.0022 18.0 0.4 0.005 16.9 0.4 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EEB08495.1 - 0.016 14.9 0.8 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 TPR repeat MFS_1 PF07690.16 EEB08496.1 - 5.5e-28 97.9 43.0 1.3e-24 86.9 27.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB08496.1 - 1.4e-11 43.9 11.6 1.4e-11 43.9 11.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3099 PF11298.8 EEB08496.1 - 0.4 10.8 9.1 5.3 7.3 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3099) Pyr_redox_2 PF07992.14 EEB08497.1 - 2e-49 168.4 0.7 2.3e-49 168.2 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEB08497.1 - 5.8e-18 65.2 0.5 4.8e-15 55.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB08497.1 - 2.9e-15 56.3 0.2 6.7e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EEB08497.1 - 0.00017 22.0 0.1 0.035 14.5 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EEB08497.1 - 0.00018 20.9 0.2 0.05 12.8 0.0 2.6 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.24 EEB08497.1 - 0.0004 20.1 1.4 0.26 10.8 0.3 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EEB08497.1 - 0.0005 19.4 0.7 0.0019 17.5 0.1 2.1 2 1 1 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 EEB08497.1 - 0.001 19.2 1.1 0.043 14.0 0.1 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EEB08497.1 - 0.0016 17.6 3.9 0.075 12.1 0.7 3.4 2 2 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EEB08497.1 - 0.0027 16.9 0.3 0.7 9.0 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EEB08497.1 - 0.013 14.6 3.9 0.13 11.3 0.5 2.9 3 1 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 EEB08497.1 - 0.018 14.4 0.2 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EEB08497.1 - 0.019 13.7 0.6 0.07 11.8 0.4 2.1 2 1 1 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 EEB08497.1 - 0.05 13.6 0.0 8.8 6.3 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EEB08497.1 - 0.092 11.6 1.2 0.16 10.8 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase IlvN PF07991.12 EEB08497.1 - 0.11 12.0 0.1 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EEB08497.1 - 0.13 12.0 1.4 7.8 6.1 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Nop14 PF04147.12 EEB08498.1 - 1.6e-233 777.7 53.5 1.3e-232 774.7 53.5 1.9 1 1 0 1 1 1 1 Nop14-like family RhoGAP PF00620.27 EEB08499.1 - 1.3e-36 125.7 0.1 3.5e-36 124.3 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEB08499.1 - 4.1e-20 71.8 44.6 3e-12 46.6 5.5 5.3 5 0 0 5 5 5 2 LIM domain Alg6_Alg8 PF03155.15 EEB08500.1 - 6.2e-124 414.6 38.0 1.7e-123 413.2 38.0 1.5 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RINGv PF12906.7 EEB08501.1 - 1.2e-15 57.3 11.6 2.8e-15 56.1 11.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EEB08501.1 - 0.64 10.4 11.8 1.4 9.3 11.8 1.6 1 0 0 1 1 1 0 Ring finger domain SAPS PF04499.15 EEB08501.1 - 1.8 7.2 10.7 5.5 5.7 10.7 1.6 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein ABC_tran PF00005.27 EEB08502.1 - 9.4e-33 113.6 0.0 2.6e-18 66.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EEB08502.1 - 6.2e-13 48.3 4.1 1.7e-12 47.0 4.1 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EEB08502.1 - 1.6e-10 40.8 1.5 0.005 16.3 0.5 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEB08502.1 - 2.7e-08 34.0 7.7 0.51 10.1 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EEB08502.1 - 2.9e-07 30.0 2.5 2.9e-07 30.0 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 EEB08502.1 - 1.4e-05 25.3 0.0 0.0039 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EEB08502.1 - 1.7e-05 24.7 0.2 0.14 11.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EEB08502.1 - 1.8e-05 25.2 0.0 0.039 14.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EEB08502.1 - 2.8e-05 24.1 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 EEB08502.1 - 3.7e-05 23.6 2.1 3.7e-05 23.6 2.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 EEB08502.1 - 7.7e-05 22.7 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 EEB08502.1 - 0.00039 19.7 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EEB08502.1 - 0.00046 20.6 0.0 1.3 9.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EEB08502.1 - 0.00051 20.6 0.0 1.9 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEB08502.1 - 0.00063 19.4 1.0 1.4 8.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EEB08502.1 - 0.00082 19.3 0.1 0.19 11.6 0.1 2.3 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.7 EEB08502.1 - 0.0011 19.5 6.5 0.0019 18.7 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EEB08502.1 - 0.0013 18.8 11.3 0.0026 17.9 11.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 EEB08502.1 - 0.0015 18.3 0.6 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 EEB08502.1 - 0.0024 17.8 1.0 0.0024 17.8 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.22 EEB08502.1 - 0.0029 18.0 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Fer4_10 PF13237.6 EEB08502.1 - 0.0031 17.6 1.4 0.0031 17.6 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_23 PF13476.6 EEB08502.1 - 0.0039 17.7 0.6 0.63 10.5 0.4 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EEB08502.1 - 0.0045 16.6 2.7 0.13 11.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 EEB08502.1 - 0.0049 16.9 0.1 0.06 13.3 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 EEB08502.1 - 0.0086 16.2 11.5 0.018 15.2 11.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EEB08502.1 - 0.015 16.2 0.2 0.015 16.2 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_33 PF13671.6 EEB08502.1 - 0.022 14.9 0.0 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EEB08502.1 - 0.027 14.7 0.0 4.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEB08502.1 - 0.049 13.7 0.0 4.5 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Fer4_17 PF13534.6 EEB08502.1 - 0.065 13.8 0.9 0.065 13.8 0.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain VirE PF05272.11 EEB08502.1 - 0.089 12.5 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_13 PF13166.6 EEB08502.1 - 0.1 11.2 0.5 0.23 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEB08502.1 - 0.1 12.3 0.1 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EEB08502.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC Thymidylate_kin PF02223.17 EEB08502.1 - 0.13 12.0 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Fer4_4 PF12800.7 EEB08502.1 - 0.13 12.8 12.2 0.083 13.4 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_5 PF07728.14 EEB08502.1 - 0.17 11.9 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EEB08502.1 - 0.2 11.7 1.2 22 5.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EEB08502.1 - 0.41 10.4 1.7 0.66 9.7 0.0 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EEB08502.1 - 0.75 9.7 2.3 25 4.8 0.1 3.0 3 0 0 3 3 3 0 NTPase Fer4_8 PF13183.6 EEB08502.1 - 1.2 9.6 10.4 0.23 11.9 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EEB08502.1 - 6.7 7.9 15.4 0.55 11.3 3.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain S-AdoMet_synt_C PF02773.16 EEB08503.1 - 5.8e-65 217.4 0.0 1.2e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EEB08503.1 - 3.8e-45 152.6 0.6 8.3e-45 151.5 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EEB08503.1 - 1.5e-44 151.1 0.0 2.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EEB08503.1 - 0.045 12.5 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PGK PF00162.19 EEB08504.1 - 3.4e-149 496.9 2.2 3.8e-149 496.7 2.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HEAT PF02985.22 EEB08505.1 - 3e-20 70.5 15.3 1.6e-05 24.8 0.1 11.6 13 0 0 13 13 12 4 HEAT repeat HEAT_EZ PF13513.6 EEB08505.1 - 3.1e-20 72.3 0.4 6.1e-06 26.6 0.0 9.1 10 0 0 10 10 9 2 HEAT-like repeat HEAT_2 PF13646.6 EEB08505.1 - 2.7e-15 56.5 0.8 1.8e-05 25.0 0.0 8.0 7 2 1 8 8 8 2 HEAT repeats IBN_N PF03810.19 EEB08505.1 - 1.2e-11 44.4 5.8 1.4e-10 40.9 0.2 4.5 5 0 0 5 5 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EEB08505.1 - 1.5e-11 44.7 5.1 0.072 13.7 0.0 7.5 6 2 1 8 8 6 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EEB08505.1 - 3.3e-11 42.9 4.5 3.8e-08 32.9 0.0 4.4 5 1 0 5 5 5 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EEB08505.1 - 2.7e-07 30.8 6.5 0.16 12.0 0.0 5.7 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EEB08505.1 - 8.2e-07 28.8 7.9 1.9 8.0 0.0 6.5 5 2 1 7 7 7 2 CLASP N terminal RTP1_C1 PF10363.9 EEB08505.1 - 2.3e-05 24.5 3.8 0.62 10.3 0.0 5.1 4 1 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 EEB08505.1 - 0.00031 20.4 3.2 1.4 8.4 0.0 4.8 3 3 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II NopRA1 PF16201.5 EEB08505.1 - 0.00049 19.7 1.6 2.3 7.7 0.0 4.5 3 1 1 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 EEB08505.1 - 0.0057 16.1 0.5 0.078 12.3 0.3 2.7 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Anticodon_1 PF08264.13 EEB08505.1 - 0.011 15.7 0.1 0.061 13.3 0.0 2.3 2 0 0 2 2 1 0 Anticodon-binding domain of tRNA DRIM PF07539.12 EEB08505.1 - 0.032 12.5 2.2 2.5 6.3 0.2 4.2 5 1 0 5 5 5 0 Down-regulated in metastasis Arm PF00514.23 EEB08505.1 - 0.04 14.0 0.0 31 4.8 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 EEB08505.1 - 0.08 12.5 0.1 1 8.8 0.0 2.7 2 0 0 2 2 2 0 Tti2 family CLP1_P PF16575.5 EEB08505.1 - 0.092 12.5 0.1 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NUC173 PF08161.12 EEB08505.1 - 0.094 12.4 1.1 13 5.3 0.0 4.2 4 1 0 4 4 4 0 NUC173 domain Cohesin_HEAT PF12765.7 EEB08505.1 - 0.13 12.6 0.1 0.83 10.0 0.1 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Phage_TAC_9 PF10876.8 EEB08505.1 - 0.13 12.3 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 1 0 Phage tail assemb.y chaperone protein, TAC FlaF PF07309.11 EEB08505.1 - 0.28 11.2 2.0 1.2 9.1 0.0 3.2 4 0 0 4 4 4 0 Flagellar protein FlaF Cnd3 PF12719.7 EEB08505.1 - 0.87 8.7 12.4 1.7 7.8 0.1 4.9 5 1 1 6 6 6 0 Nuclear condensing complex subunits, C-term domain HEAT_PBS PF03130.16 EEB08505.1 - 2.5 9.0 4.7 1.3e+02 3.7 0.1 5.3 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat SdrG_C_C PF10425.9 EEB08506.1 - 0.008 16.3 1.7 0.016 15.3 1.7 1.5 1 0 0 1 1 1 1 C-terminus of bacterial fibrinogen-binding adhesin Trs65 PF12735.7 EEB08506.1 - 0.03 13.7 0.0 0.68 9.3 0.0 2.7 1 1 1 2 2 2 0 TRAPP trafficking subunit Trs65 A2M PF00207.22 EEB08506.1 - 0.039 13.8 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin family SYF2 PF08231.12 EEB08506.1 - 0.068 13.6 8.5 0.18 12.2 7.7 2.0 1 1 1 2 2 2 0 SYF2 splicing factor NtA PF03146.15 EEB08506.1 - 0.087 12.7 0.0 0.56 10.1 0.1 2.2 2 0 0 2 2 2 0 Agrin NtA domain JmjC PF02373.22 EEB08507.1 - 1.6e-09 38.2 0.4 2.5e-08 34.3 0.4 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 EEB08507.1 - 3.4e-05 24.3 0.6 3.4e-05 24.3 0.6 2.5 3 0 0 3 3 3 1 Jumonji helical domain Cupin_8 PF13621.6 EEB08507.1 - 0.0041 16.9 1.8 0.0075 16.0 0.0 2.2 2 0 0 2 2 2 1 Cupin-like domain AP_endonuc_2 PF01261.24 EEB08508.2 - 1.3e-30 106.4 0.1 2e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_L6e PF01159.19 EEB08509.1 - 1.2e-36 125.6 0.0 2.6e-36 124.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e KOW PF00467.29 EEB08509.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.2 2 1 1 3 3 3 0 KOW motif MFS_1 PF07690.16 EEB08510.1 - 2.3e-15 56.4 42.5 2.2e-10 40.0 22.8 3.2 2 1 2 4 4 4 2 Major Facilitator Superfamily TFIID-18kDa PF02269.16 EEB08511.1 - 2.8e-38 129.8 2.6 7.3e-38 128.5 0.8 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Carb_kinase PF01256.17 EEB08512.1 - 3.4e-57 193.7 0.0 4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EEB08512.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Yip1 PF04893.17 EEB08513.2 - 4.3e-10 39.6 10.9 7e-10 38.9 10.9 1.4 1 1 0 1 1 1 1 Yip1 domain Cys_Met_Meta_PP PF01053.20 EEB08514.1 - 5.4e-126 420.2 0.0 6.1e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEB08514.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EEB08514.1 - 0.0023 16.5 0.0 0.012 14.2 0.0 1.9 2 0 0 2 2 2 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EEB08514.1 - 0.15 11.3 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_C13 PF01650.18 EEB08515.1 - 3.5e-39 134.9 0.0 4.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Host_attach PF10116.9 EEB08515.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells Dynamitin PF04912.14 EEB08516.1 - 9.1e-11 41.7 27.2 2.7e-10 40.1 27.2 1.8 1 1 0 1 1 1 1 Dynamitin GBR2_CC PF18455.1 EEB08516.1 - 0.02 15.0 0.4 0.11 12.6 0.4 2.3 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Pox_A_type_inc PF04508.12 EEB08516.1 - 0.099 12.5 4.5 5.8 6.9 0.3 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NAPRTase_C PF17956.1 EEB08516.1 - 0.58 10.6 6.3 0.43 11.0 1.0 2.6 2 1 1 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain MbeD_MobD PF04899.12 EEB08516.1 - 1.3 9.2 11.3 3.7 7.7 1.0 3.6 4 0 0 4 4 4 0 MbeD/MobD like Prefoldin PF02996.17 EEB08516.1 - 3.5 7.6 21.6 1.4 8.8 0.8 4.7 4 1 0 4 4 4 0 Prefoldin subunit PPR_3 PF13812.6 EEB08517.1 - 7e-29 99.7 0.9 1.1e-25 89.5 0.5 2.5 2 0 0 2 2 2 2 Pentatricopeptide repeat domain ATP13 PF12921.7 EEB08517.1 - 4.1e-18 65.3 1.3 3.4e-16 59.1 0.1 3.0 1 1 2 3 3 3 2 Mitochondrial ATPase expression PPR_2 PF13041.6 EEB08517.1 - 0.0014 18.7 1.0 26 5.1 0.1 4.0 3 1 1 4 4 4 0 PPR repeat family PPR_1 PF12854.7 EEB08517.1 - 0.042 13.6 0.9 7.7 6.3 0.1 3.0 3 0 0 3 3 3 0 PPR repeat LexA_DNA_bind PF01726.16 EEB08517.1 - 0.047 13.5 0.1 1.1 9.0 0.0 2.9 2 0 0 2 2 2 0 LexA DNA binding domain DUF1664 PF07889.12 EEB08517.1 - 0.05 13.6 0.1 0.39 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1828 PF08861.10 EEB08517.1 - 0.12 12.6 0.3 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Med10 PF09748.9 EEB08517.1 - 0.53 10.3 2.7 5.8 6.9 0.4 3.0 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex KxDL PF10241.9 EEB08517.1 - 2.1 8.7 7.7 0.39 11.0 0.6 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein XPG_I PF00867.18 EEB08518.2 - 2.8e-20 72.4 0.2 8.8e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 XPG I-region GDA1_CD39 PF01150.17 EEB08519.1 - 4.6e-116 388.0 0.0 7.4e-116 387.3 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PAXNEB PF05625.11 EEB08520.1 - 1.8e-81 274.2 0.0 2.2e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein IF-2B PF01008.17 EEB08521.1 - 1.8e-66 224.3 0.0 2.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pantoate_ligase PF02569.15 EEB08522.1 - 1.3e-99 332.7 0.1 1.5e-99 332.6 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 EEB08522.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP-sulfurylase MMS1_N PF10433.9 EEB08523.1 - 3.3e-20 72.2 1.8 4.4e-20 71.8 1.2 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEB08523.1 - 1.5e-09 37.6 0.4 5.5e-09 35.8 0.1 2.1 2 0 0 2 2 2 1 CPSF A subunit region B56 PF01603.20 EEB08524.2 - 5.9e-173 575.6 6.3 6.8e-173 575.4 6.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EEB08524.2 - 0.004 17.1 5.5 0.22 11.4 0.9 2.5 2 1 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2122 PF09895.9 EEB08524.2 - 0.12 12.7 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Cnd3 PF12719.7 EEB08525.1 - 8e-78 261.6 5.6 2.8e-77 259.8 5.6 2.0 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EEB08525.1 - 4.1e-10 39.9 8.1 1.3e-05 25.4 1.1 4.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EEB08525.1 - 8.4e-07 28.7 8.1 4.3 7.9 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat WSN PF02206.18 EEB08525.1 - 0.02 14.8 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function Cnd1 PF12717.7 EEB08525.1 - 0.023 14.8 12.1 0.025 14.6 0.9 5.0 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEB08525.1 - 0.04 14.4 7.3 2.2 8.9 0.2 5.5 5 1 2 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.16 EEB08525.1 - 0.1 13.4 0.3 0.62 10.9 0.0 2.7 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Spindle_Spc25 PF08234.12 EEB08526.2 - 7.2e-23 80.6 3.0 7.2e-23 80.6 3.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 FapA PF03961.13 EEB08526.2 - 1.1 7.7 11.8 1.6 7.2 11.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A VSG_B PF13206.6 EEB08526.2 - 1.2 8.3 8.1 1.7 7.8 8.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain SRP54 PF00448.22 EEB08527.1 - 3.2e-80 268.4 0.5 2e-78 262.6 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EEB08527.1 - 6.7e-30 103.6 5.7 6.7e-30 103.6 5.7 4.0 2 1 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EEB08527.1 - 5.3e-19 68.2 0.4 1.3e-18 66.9 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 EEB08527.1 - 9.3e-06 25.1 0.0 2.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EEB08527.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EEB08527.1 - 2.8e-05 23.8 2.0 0.0012 18.5 1.3 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EEB08527.1 - 7.4e-05 21.9 0.0 0.0008 18.5 0.0 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EEB08527.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EEB08527.1 - 0.00073 20.0 0.1 0.016 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEB08527.1 - 0.00081 19.8 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEB08527.1 - 0.0014 18.9 0.0 0.005 17.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain SRPRB PF09439.10 EEB08527.1 - 0.0057 16.1 0.8 1.4 8.3 0.1 3.1 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EEB08527.1 - 0.0079 16.8 0.2 0.08 13.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EEB08527.1 - 0.0082 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 EEB08527.1 - 0.014 15.4 0.3 0.075 13.0 0.3 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 EEB08527.1 - 0.022 15.2 0.3 0.12 12.8 0.1 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEB08527.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EEB08527.1 - 0.037 13.9 0.2 0.39 10.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EEB08527.1 - 0.045 13.5 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 EEB08527.1 - 0.049 12.9 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CLP1_P PF16575.5 EEB08527.1 - 0.058 13.2 0.2 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MobB PF03205.14 EEB08527.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EEB08527.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EEB08527.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase MMR_HSR1 PF01926.23 EEB08527.1 - 0.12 12.5 0.2 0.69 10.0 0.2 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EEB08527.1 - 0.13 12.0 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HDA2-3 PF11496.8 EEB08528.1 - 9.1e-05 21.8 1.6 0.00031 20.0 0.5 4.0 3 1 1 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 DUF4055 PF13264.6 EEB08528.1 - 0.36 11.0 7.2 0.63 10.2 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) ATG16 PF08614.11 EEB08528.1 - 0.92 9.7 41.3 0.025 14.8 13.3 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EEB08528.1 - 6.5 6.5 40.9 3.9 7.2 15.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) UCH PF00443.29 EEB08529.2 - 4e-50 170.7 0.1 5.6e-50 170.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB08529.2 - 2.2e-24 86.7 0.0 2e-23 83.5 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1958 PF09211.10 EEB08529.2 - 0.095 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) SKIP_SNW PF02731.15 EEB08530.2 - 5.4e-73 243.9 2.9 5.4e-73 243.9 2.9 2.1 2 0 0 2 2 2 1 SKIP/SNW domain Corona_nucleoca PF00937.18 EEB08530.2 - 0.018 14.1 4.5 0.034 13.2 4.5 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 EEB08530.2 - 0.36 10.5 16.7 0.82 9.4 16.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Septin PF00735.18 EEB08531.1 - 4.6e-97 324.7 0.1 7.4e-97 324.0 0.1 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 EEB08531.1 - 1.2e-08 34.7 1.7 2e-07 30.7 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB08531.1 - 8.6e-06 25.8 3.2 3.1e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EEB08531.1 - 5.6e-05 23.2 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEB08531.1 - 0.00079 18.8 1.8 0.039 13.3 0.0 2.8 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EEB08531.1 - 0.0026 18.1 0.1 0.01 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 EEB08531.1 - 0.0033 17.6 0.4 0.0086 16.3 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EEB08531.1 - 0.0035 17.1 2.3 0.11 12.2 0.4 3.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EEB08531.1 - 0.0098 15.1 0.1 0.0098 15.1 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EEB08531.1 - 0.019 14.7 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EEB08531.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 EEB08531.1 - 0.04 13.2 1.1 0.082 12.2 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Pox_A_type_inc PF04508.12 EEB08531.1 - 0.048 13.5 1.0 8.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RuvB_N PF05496.12 EEB08531.1 - 0.052 13.3 0.0 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF4094 PF13334.6 EEB08531.1 - 0.067 13.6 2.7 0.16 12.4 2.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Dynamin_N PF00350.23 EEB08531.1 - 0.068 13.2 6.1 4.6 7.3 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_7 PF12775.7 EEB08531.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Exonuc_VII_L PF02601.15 EEB08531.1 - 0.2 11.2 3.9 0.24 10.9 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 EEB08531.1 - 0.21 12.3 4.7 0.64 10.8 4.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Streptin-Immun PF11083.8 EEB08531.1 - 0.36 11.3 7.3 0.19 12.1 2.2 2.7 3 0 0 3 3 2 0 Lantibiotic streptin immunity protein AAA_18 PF13238.6 EEB08531.1 - 0.39 11.3 6.9 0.11 13.1 0.6 2.8 2 2 0 2 2 2 0 AAA domain FAM76 PF16046.5 EEB08531.1 - 0.57 9.5 6.8 0.94 8.8 6.8 1.3 1 0 0 1 1 1 0 FAM76 protein Ribonuclease_3 PF00636.26 EEB08532.1 - 1.6e-38 131.5 0.0 9.9e-22 77.6 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEB08532.1 - 8.8e-22 77.6 0.0 2.9e-13 50.1 0.1 3.8 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 EEB08532.1 - 3.1e-18 66.2 0.2 1.2e-17 64.2 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 EEB08532.1 - 1.1e-17 64.0 0.1 3.6e-17 62.3 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 EEB08532.1 - 4.1e-16 59.5 0.1 3.1e-15 56.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEB08532.1 - 1.2e-14 54.5 0.0 4.1e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.26 EEB08532.1 - 9.2e-06 26.3 1.5 0.0026 18.4 0.0 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif IstB_IS21 PF01695.17 EEB08532.1 - 0.17 11.6 0.2 8.7 6.0 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Svf1_C PF17187.4 EEB08533.2 - 2.3e-52 177.2 0.1 6.8e-52 175.6 0.0 1.9 3 0 0 3 3 3 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EEB08533.2 - 5.1e-51 173.0 0.5 7.4e-51 172.4 0.5 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Antimicrobial14 PF08109.11 EEB08533.2 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Lactocin 705 family Atx10homo_assoc PF09759.9 EEB08534.2 - 4.8e-34 116.3 1.1 1.6e-33 114.6 0.3 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain IBN_N PF03810.19 EEB08535.1 - 2.6e-18 65.7 0.1 1.1e-17 63.7 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 EEB08535.1 - 9.1e-09 34.6 0.6 2.9e-08 33.0 0.2 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 EEB08535.1 - 1.7e-08 34.6 3.7 4.2e-07 30.1 0.2 3.7 3 1 0 3 3 3 1 Exportin 1-like protein RIX1 PF08167.12 EEB08535.1 - 0.00068 19.4 5.3 0.91 9.2 0.1 4.7 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EEB08535.1 - 0.011 16.1 1.0 7.9 7.0 0.1 2.9 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EEB08535.1 - 0.12 12.7 0.2 1.1 9.7 0.2 2.9 1 0 0 1 1 1 0 HEAT repeat CLASP_N PF12348.8 EEB08535.1 - 0.19 11.3 4.8 13 5.3 0.1 4.1 3 1 2 5 5 5 0 CLASP N terminal Actin PF00022.19 EEB08536.2 - 5.8e-77 259.0 0.0 4.3e-76 256.1 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEB08536.2 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Peptidase_C13 PF01650.18 EEB08536.2 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase C13 family Dfp1_Him1_M PF08630.10 EEB08537.1 - 1.7e-35 122.0 0.1 9.6e-35 119.6 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EEB08537.1 - 1.9e-19 69.5 1.2 3.3e-19 68.7 1.2 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EEB08537.1 - 0.00011 22.5 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEB08537.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 EEB08537.1 - 0.017 15.5 0.0 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-C2H2_2 PF12756.7 EEB08537.1 - 0.018 15.4 0.2 0.043 14.2 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) KH_1 PF00013.29 EEB08538.1 - 2.7e-104 341.0 64.5 1.6e-14 53.5 1.0 15.0 14 1 0 14 14 14 13 KH domain KH_2 PF07650.17 EEB08538.1 - 9.5e-06 25.4 42.4 0.075 12.9 3.2 9.9 9 3 2 11 11 11 5 KH domain AHJR-like PF18743.1 EEB08538.1 - 0.0053 16.3 0.1 0.026 14.1 0.1 2.2 1 0 0 1 1 1 1 REase_AHJR-like BMC PF00936.19 EEB08538.1 - 0.0082 16.1 4.9 9.8 6.3 0.2 6.3 7 0 0 7 7 7 1 BMC domain FCD PF07729.12 EEB08538.1 - 0.096 13.1 0.0 34 4.9 0.0 3.4 3 0 0 3 3 3 0 FCD domain DUF4816 PF16086.5 EEB08538.1 - 0.19 11.7 1.7 0.64 10.0 1.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) DUF3502 PF12010.8 EEB08538.1 - 0.38 11.4 3.2 3.2 8.4 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3502) Methyltransf_FA PF12248.8 EEB08538.1 - 1.1 9.6 4.5 7 7.0 0.3 3.3 3 0 0 3 3 3 0 Farnesoic acid 0-methyl transferase zf-C2H2_2 PF12756.7 EEB08539.1 - 1.1e-33 115.6 15.9 5.4e-30 103.7 2.1 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EEB08539.1 - 1.4e-11 44.3 17.6 1.9e-05 24.8 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EEB08539.1 - 5.3e-07 29.9 14.8 0.17 12.8 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 EEB08539.1 - 4.2e-06 27.0 0.4 4.2e-06 27.0 0.4 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EEB08539.1 - 0.0048 17.3 18.8 0.79 10.3 0.3 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type SnoaL_2 PF12680.7 EEB08539.1 - 0.0054 17.3 0.1 0.26 12.0 0.1 2.8 2 1 0 2 2 2 1 SnoaL-like domain zf-Mss51 PF13824.6 EEB08539.1 - 0.049 13.7 6.1 0.89 9.7 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_12 PF18658.1 EEB08539.1 - 0.082 12.5 1.1 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger C2H2-type STAG PF08514.11 EEB08540.1 - 1.3e-11 44.4 0.2 1.3e-11 44.4 0.2 2.9 3 0 0 3 3 3 1 STAG domain Cyclin_N PF00134.23 EEB08541.1 - 4.9e-41 139.4 0.6 9.1e-41 138.6 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB08541.1 - 1.4e-32 112.3 0.1 2.8e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PGP_phosphatase PF09419.10 EEB08542.2 - 3.5e-45 153.6 0.0 4.1e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EEB08542.2 - 4.3e-08 33.1 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like PfkB PF00294.24 EEB08542.2 - 0.047 13.0 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase MIT_C PF16565.5 EEB08542.2 - 0.049 13.6 0.1 0.086 12.8 0.1 1.4 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT DUF3600 PF12207.8 EEB08542.2 - 0.1 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) SpoVT_C PF15714.5 EEB08542.2 - 0.11 12.6 0.3 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Fe-S_biosyn PF01521.20 EEB08543.1 - 5.4e-21 74.9 0.1 7.2e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MAGE PF01454.19 EEB08544.1 - 1.8e-41 142.2 0.1 3.7e-41 141.2 0.1 1.6 1 0 0 1 1 1 1 MAGE family Myosin_head PF00063.21 EEB08545.1 - 4.3e-266 884.5 8.2 4.3e-266 884.5 8.2 2.5 2 1 0 2 2 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EEB08545.1 - 1.1e-08 34.7 0.9 1.9e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain CALCOCO1 PF07888.11 EEB08545.1 - 0.0016 17.4 42.2 0.0016 17.4 42.2 4.2 1 1 3 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.7 EEB08545.1 - 0.0035 17.5 12.8 0.0035 17.5 12.8 8.9 1 1 6 7 7 6 1 Tropomyosin like TPR_MLP1_2 PF07926.12 EEB08545.1 - 0.013 15.5 144.3 0.068 13.2 6.9 8.6 1 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein AAA_22 PF13401.6 EEB08545.1 - 0.054 13.8 0.0 0.054 13.8 0.0 4.1 4 1 0 4 4 3 0 AAA domain ATG16 PF08614.11 EEB08545.1 - 0.19 11.9 142.5 0.018 15.3 11.0 7.4 1 1 5 6 6 4 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EEB08545.1 - 0.23 10.3 140.0 0.01 14.7 11.5 6.7 1 1 5 6 6 6 0 Spc7 kinetochore protein AAA_16 PF13191.6 EEB08545.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.9 3 1 0 3 3 2 0 AAA ATPase domain Myosin_tail_1 PF01576.19 EEB08545.1 - 3.3 5.4 142.9 0.021 12.6 79.2 3.1 1 1 2 3 3 3 0 Myosin tail MAD PF05557.13 EEB08545.1 - 7.4 4.8 140.8 0.007 14.8 65.8 3.8 1 1 3 4 4 4 0 Mitotic checkpoint protein CNH PF00780.22 EEB08546.2 - 1.8e-34 119.6 0.0 2.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EEB08546.2 - 4.4e-33 115.0 0.0 1.1e-32 113.8 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EEB08546.2 - 2.9e-19 69.5 2.8 1e-18 67.8 2.8 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEB08546.2 - 4.3e-05 24.0 0.6 0.0038 17.7 0.6 3.1 1 1 0 1 1 1 1 PH domain PH_16 PF17838.1 EEB08546.2 - 0.0085 15.9 0.5 0.64 9.9 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 EEB08546.2 - 0.43 10.4 3.8 12 5.7 3.7 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain CNH PF00780.22 EEB08547.1 - 7.1e-83 278.4 0.0 1.3e-82 277.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EEB08547.1 - 9.2e-37 126.2 0.2 2.1e-36 125.0 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EEB08547.1 - 1.4e-33 116.7 0.7 2.4e-33 115.9 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EEB08547.1 - 2.2e-12 46.9 0.0 4.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 EEB08547.1 - 0.081 12.8 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 PH domain SNase PF00565.17 EEB08548.1 - 6.7e-65 216.3 0.0 4.8e-14 52.7 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EEB08548.1 - 2.9e-20 72.5 0.0 8.4e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Tudor domain PRK PF00485.18 EEB08550.2 - 7.3e-61 205.3 0.0 1.1e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EEB08550.2 - 7e-28 97.5 0.1 1.1e-27 96.9 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EEB08550.2 - 1.1e-05 26.0 0.0 2.8e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEB08550.2 - 5.2e-05 23.4 0.0 0.00015 21.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 EEB08550.2 - 6.8e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EEB08550.2 - 9.7e-05 22.8 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain dNK PF01712.19 EEB08550.2 - 0.0025 17.7 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.6 EEB08550.2 - 0.0032 17.9 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EEB08550.2 - 0.0033 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 EEB08550.2 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EEB08550.2 - 0.006 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EDR1 PF14381.6 EEB08550.2 - 0.0064 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Cytidylate_kin PF02224.18 EEB08550.2 - 0.013 15.3 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 EEB08550.2 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 EEB08550.2 - 0.015 15.4 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EEB08550.2 - 0.02 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB08550.2 - 0.026 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EEB08550.2 - 0.033 14.7 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 EEB08550.2 - 0.036 13.7 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 EEB08550.2 - 0.057 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EEB08550.2 - 0.063 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 EEB08550.2 - 0.073 12.7 0.0 0.098 12.3 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 EEB08550.2 - 0.11 12.3 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SSE PF00437.20 EEB08550.2 - 0.12 11.4 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.22 EEB08550.2 - 0.14 12.2 0.0 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Pkinase PF00069.25 EEB08551.1 - 9.5e-62 208.7 0.0 1.1e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08551.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08551.1 - 8.2e-08 31.9 0.0 2.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEB08551.1 - 7.5e-06 25.4 0.2 1.3e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB08551.1 - 0.00016 20.6 0.1 0.00053 18.9 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EEB08551.1 - 0.01 15.8 0.4 0.022 14.7 0.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEB08551.1 - 0.017 14.1 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain MMM1 PF10296.9 EEB08552.1 - 3.8e-07 29.5 9.7 4.8e-06 25.9 1.3 3.6 1 1 2 3 3 3 2 Maintenance of mitochondrial morphology protein 1 WTF PF03303.13 EEB08552.1 - 0.22 11.2 2.2 0.31 10.7 2.2 1.3 1 1 0 1 1 1 0 WTF protein BCAS2 PF05700.11 EEB08553.2 - 7.3e-24 84.6 0.2 9.9e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MTHFR PF02219.17 EEB08554.1 - 2.4e-118 394.6 0.0 3.4e-118 394.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_8 PF05148.15 EEB08555.1 - 4.8e-84 281.6 0.0 5.8e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EEB08555.1 - 2.1e-08 34.7 0.1 1e-07 32.5 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08555.1 - 1.2e-07 32.4 0.2 9.4e-06 26.2 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08555.1 - 3.6e-07 30.1 0.0 0.0011 18.8 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.14 EEB08555.1 - 0.00034 20.2 0.1 0.46 10.0 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.18 EEB08555.1 - 0.0072 15.7 0.0 0.025 13.9 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EEB08555.1 - 0.17 11.9 2.5 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08555.1 - 0.52 11.1 2.7 0.96 10.2 0.1 2.7 2 1 0 2 2 2 0 Methyltransferase domain His_Phos_1 PF00300.22 EEB08556.1 - 1.3e-14 54.3 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HMG-CoA_red PF00368.18 EEB08557.2 - 5.7e-139 463.2 3.0 8e-139 462.7 3.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EEB08557.2 - 8.6e-10 38.7 5.9 8.6e-10 38.7 5.9 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 EEB08557.2 - 3.7e-05 23.6 0.3 0.00013 21.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain with HPIH motif DUF3173 PF11372.8 EEB08557.2 - 0.029 14.2 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Reg_prop PF07494.11 EEB08558.1 - 0.13 12.6 0.0 3.2 8.3 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller TPR_1 PF00515.28 EEB08559.1 - 9.5e-49 161.3 24.9 2.9e-07 30.0 0.0 9.8 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 EEB08559.1 - 5.2e-38 128.8 8.6 5.9e-22 77.4 0.7 2.7 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EEB08559.1 - 1.2e-36 121.8 25.2 0.00019 21.3 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 EEB08559.1 - 4.7e-22 76.3 24.3 0.00083 19.4 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EEB08559.1 - 9.9e-22 76.4 17.5 7.6e-06 25.5 0.0 7.9 5 2 2 7 7 7 5 TPR repeat TPR_12 PF13424.6 EEB08559.1 - 2.8e-19 69.2 16.8 1.7e-08 34.7 1.7 6.9 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08559.1 - 2.3e-18 66.4 9.9 0.0017 18.8 0.3 7.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EEB08559.1 - 2.5e-17 63.2 1.6 0.00034 21.2 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08559.1 - 7e-17 60.7 5.6 0.26 12.2 0.0 8.0 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEB08559.1 - 3e-14 51.9 3.7 2.2e-06 27.3 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEB08559.1 - 7.5e-13 47.9 5.3 0.018 15.4 0.1 8.1 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EEB08559.1 - 1e-10 41.6 1.3 0.00068 19.7 0.0 5.3 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08559.1 - 1.1e-09 37.8 12.0 0.037 13.9 0.0 6.3 8 0 0 8 8 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEB08559.1 - 1.1e-06 28.6 2.9 12 6.1 0.0 6.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EEB08559.1 - 1.4e-06 28.6 18.9 0.026 15.1 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEB08559.1 - 4.1e-05 22.9 9.7 0.056 12.7 1.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 EEB08559.1 - 0.00075 19.4 14.1 0.84 9.7 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EEB08559.1 - 0.0013 18.5 7.3 0.3 10.8 0.2 4.6 4 0 0 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 ANAPC3 PF12895.7 EEB08559.1 - 0.0015 18.7 16.4 0.85 9.9 0.3 5.0 3 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EEB08559.1 - 0.069 12.9 10.4 7.8 6.2 0.3 4.3 3 1 1 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 EEB08559.1 - 0.087 12.3 0.5 0.94 9.0 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.14 EEB08559.1 - 0.67 10.8 4.8 63 4.6 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat XPC-binding PF09280.11 EEB08559.1 - 1.5 8.6 12.8 5.4 6.8 0.8 3.9 4 1 0 4 4 3 0 XPC-binding domain Oxysterol_BP PF01237.18 EEB08560.2 - 1.7e-83 280.5 0.3 3.3e-74 250.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Alb1 PF09135.11 EEB08561.1 - 2.7e-06 28.2 21.1 3.2e-06 27.9 21.1 1.0 1 0 0 1 1 1 1 Alb1 YfhD PF14151.6 EEB08561.1 - 0.34 11.1 10.6 0.65 10.2 0.5 2.5 1 1 1 2 2 2 0 YfhD-like protein Mob_synth_C PF06463.13 EEB08561.1 - 0.68 9.9 5.8 0.42 10.5 2.4 2.0 1 1 1 2 2 2 0 Molybdenum Cofactor Synthesis C Agouti PF05039.12 EEB08561.1 - 9.2 7.1 8.6 4.5 8.1 6.3 1.7 1 1 1 2 2 2 0 Agouti protein PI3_PI4_kinase PF00454.27 EEB08562.1 - 3.2e-48 164.7 0.0 1e-47 163.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EEB08562.1 - 5.9e-27 94.7 2.1 5.9e-27 94.7 2.1 3.2 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EEB08562.1 - 2.2e-09 37.0 0.0 5.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 FATC domain CRAL_TRIO PF00650.20 EEB08563.1 - 3.7e-37 127.5 0.0 7.2e-37 126.6 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEB08563.1 - 9.6e-16 57.7 0.9 2e-15 56.7 0.9 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEB08563.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Ndc1_Nup PF09531.10 EEB08563.1 - 0.39 9.3 4.8 0.61 8.7 4.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rep_fac-A_3 PF08661.11 EEB08564.1 - 1.4e-29 102.5 0.1 1.6e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 PGM_PMM_I PF02878.16 EEB08565.1 - 7e-19 67.9 0.1 4.2e-08 33.0 0.0 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EEB08565.1 - 3.5e-09 36.7 0.1 9.1e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EEB08565.1 - 0.00013 22.5 0.2 0.0011 19.6 0.2 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEB08565.1 - 0.035 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CdiI_2 PF18593.1 EEB08565.1 - 0.16 12.7 0.1 16 6.2 0.0 3.1 3 0 0 3 3 3 0 CdiI immunity protein HhH-GPD PF00730.25 EEB08566.1 - 1.3e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEB08566.1 - 1.3e-07 31.1 0.0 4.1e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF4611 PF15387.6 EEB08566.1 - 0.065 13.5 2.9 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Solute_trans_a PF03619.16 EEB08567.1 - 3.3e-85 285.8 7.2 4e-85 285.6 7.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Clat_adaptor_s PF01217.20 EEB08568.1 - 1.2e-49 167.9 0.2 1.4e-49 167.6 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MMS1_N PF10433.9 EEB08570.2 - 4.2e-34 118.0 0.9 1.1e-33 116.7 0.2 2.1 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEB08570.2 - 3.1e-15 56.3 0.5 1.2e-14 54.3 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region Nup_retrotrp_bd PF10599.9 EEB08571.1 - 7.3e-05 23.4 21.2 7.3e-05 23.4 21.2 10.7 1 1 6 7 7 7 1 Retro-transposon transporting motif AFOR_C PF01314.18 EEB08571.1 - 0.3 10.1 0.6 0.45 9.5 0.6 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DEAD PF00270.29 EEB08572.1 - 3.4e-48 163.7 0.0 6.3e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB08572.1 - 1.5e-28 99.3 1.0 1.2e-26 93.2 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CagD PF16567.5 EEB08572.1 - 0.034 13.9 1.4 0.077 12.8 1.4 1.5 1 0 0 1 1 1 0 Pathogenicity island component CagD AAA_22 PF13401.6 EEB08572.1 - 0.16 12.2 0.2 0.62 10.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.28 EEB08573.1 - 4.8e-58 196.8 0.0 1.8e-34 119.1 0.0 4.7 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 EEB08573.1 - 1e-08 35.9 1.4 2.3e-08 34.8 1.4 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain PLATZ PF04640.14 EEB08573.1 - 0.5 11.0 3.2 0.44 11.2 0.8 2.2 2 0 0 2 2 2 0 PLATZ transcription factor GTP_EFTU PF00009.27 EEB08574.1 - 7.2e-35 120.3 3.8 1.2e-34 119.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEB08574.1 - 5.8e-21 74.6 0.0 1.8e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EEB08574.1 - 2.2e-12 47.2 3.4 2.8e-08 34.0 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EEB08574.1 - 1.8e-10 40.6 0.5 5.8e-10 38.9 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EEB08574.1 - 1.6e-07 31.4 1.4 8.2e-07 29.1 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EEB08574.1 - 0.00056 19.8 1.6 0.0022 17.9 0.0 2.6 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Roc PF08477.13 EEB08574.1 - 0.00067 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEB08574.1 - 0.032 13.8 0.0 0.13 11.9 0.0 2.0 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 EEB08574.1 - 0.081 13.2 0.1 0.67 10.2 0.1 2.6 1 1 0 1 1 1 0 AAA domain PCI PF01399.27 EEB08575.1 - 1.5e-08 35.1 0.1 1.5e-08 35.1 0.1 2.6 2 2 0 2 2 2 1 PCI domain TPR_12 PF13424.6 EEB08575.1 - 1.8e-05 24.9 0.8 6.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB08575.1 - 3.3e-05 23.7 0.3 0.075 13.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08575.1 - 7.9e-05 23.1 1.5 0.00015 22.2 0.2 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEB08575.1 - 0.00012 21.9 0.6 5.5 7.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 EEB08575.1 - 0.0031 17.2 0.3 0.0052 16.5 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 EEB08575.1 - 0.0058 16.4 1.0 1.3 9.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB08575.1 - 0.019 15.0 0.5 0.23 11.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08575.1 - 0.02 15.7 0.1 2.2 9.3 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB08575.1 - 0.05 14.3 0.7 6 7.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Macscav_rec PF03523.13 EEB08575.1 - 0.08 12.9 0.2 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Macrophage scavenger receptor ANAPC5 PF12862.7 EEB08575.1 - 0.69 10.0 4.8 0.73 9.9 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DRMBL PF07522.14 EEB08577.1 - 2.3e-27 95.4 0.0 5.8e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EEB08577.1 - 3.3e-07 30.0 0.0 6.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB08577.1 - 0.0026 17.8 0.2 0.0092 16.0 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RNF220 PF15926.5 EEB08577.1 - 0.0086 15.7 3.8 0.021 14.5 3.8 1.6 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 HLH PF00010.26 EEB08578.1 - 7.5e-14 51.4 0.9 1.3e-13 50.7 0.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt20 PF12090.8 EEB08578.1 - 2.8 7.5 11.7 4.7 6.7 11.7 1.3 1 0 0 1 1 1 0 Spt20 family SPC22 PF04573.12 EEB08579.1 - 7.8e-30 103.6 0.3 1.3e-27 96.3 0.3 2.1 1 1 0 1 1 1 1 Signal peptidase subunit TctC PF03401.14 EEB08579.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor DUF2434 PF10361.9 EEB08580.1 - 2e-73 247.0 5.1 2.7e-73 246.5 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) SURF4 PF02077.15 EEB08580.1 - 0.12 12.0 3.0 0.34 10.4 0.9 2.2 2 0 0 2 2 2 0 SURF4 family Inositol_P PF00459.25 EEB08581.1 - 1.9e-69 234.2 0.1 2.5e-69 233.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family CRAL_TRIO PF00650.20 EEB08582.1 - 3.8e-43 147.0 0.1 6.6e-43 146.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEB08582.1 - 7.1e-13 48.5 0.5 1.9e-12 47.1 0.5 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEB08582.1 - 7.1e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.6 EEB08582.1 - 0.014 15.2 0.2 0.03 14.1 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain TPP_enzyme_N PF02776.18 EEB08583.1 - 7e-32 110.4 0.0 1.3e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEB08583.1 - 2.2e-20 72.8 0.0 4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEB08583.1 - 1.1e-17 64.3 0.3 3.7e-17 62.5 0.0 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EEB08583.1 - 0.00036 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_M17 PF00883.21 EEB08584.1 - 1.9e-109 365.7 0.3 2.7e-109 365.2 0.3 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EEB08584.1 - 2.8e-09 36.9 0.1 6.8e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol_A_exo1 PF01612.20 EEB08585.1 - 1.9e-49 167.7 0.2 5.4e-48 163.0 0.2 2.4 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 EEB08585.1 - 7e-21 74.7 1.6 6.2e-20 71.7 0.6 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EEB08585.1 - 2.1e-15 56.4 0.0 5.5e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain AbiJ_NTD3 PF18860.1 EEB08585.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 V-ATPase_G PF03179.15 EEB08585.1 - 0.93 10.1 8.0 1.1 9.8 4.2 2.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit CRAL_TRIO PF00650.20 EEB08586.1 - 9.8e-38 129.4 0.0 1.7e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEB08586.1 - 9.4e-08 32.1 0.2 2.5e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEB08586.1 - 0.0052 16.9 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RRM_1 PF00076.22 EEB08587.2 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hepatitis_core PF00906.20 EEB08587.2 - 2.2 7.8 8.2 2.6 7.5 6.3 1.9 2 0 0 2 2 2 0 Hepatitis core antigen DEP PF00610.21 EEB08588.2 - 2.9e-14 52.9 0.0 6.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 EEB08588.2 - 9.6e-12 45.0 0.2 3.5e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Fe_bilin_red PF05996.12 EEB08588.2 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Sec10 PF07393.11 EEB08588.2 - 0.13 10.7 2.7 0.071 11.5 0.1 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec10 p450 PF00067.22 EEB08590.2 - 1.2e-73 248.4 0.0 1.5e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mnd1 PF03962.15 EEB08591.1 - 2.5e-28 98.1 0.3 2.5e-28 98.1 0.3 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EEB08591.1 - 1.6e-08 34.5 0.1 4e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 EEB08591.1 - 0.0013 19.0 0.8 0.0057 17.0 0.1 2.2 1 1 0 2 2 2 1 Penicillinase repressor HemX PF04375.14 EEB08591.1 - 0.0025 17.2 1.9 0.0034 16.7 1.9 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2802 PF10975.8 EEB08591.1 - 0.0025 17.9 4.4 4.8 7.4 0.6 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2802) DUF2203 PF09969.9 EEB08591.1 - 0.0046 17.7 3.4 0.026 15.3 0.1 2.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2203) DUF5082 PF16888.5 EEB08591.1 - 0.026 14.8 6.8 0.25 11.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) CSN5_C PF18323.1 EEB08591.1 - 0.036 15.0 1.0 0.071 14.0 0.2 1.9 2 0 0 2 2 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF5440 PF17509.2 EEB08591.1 - 0.041 13.5 0.0 0.094 12.3 0.0 1.6 2 0 0 2 2 1 0 Family of unknown function (DUF5440) Tropomyosin_1 PF12718.7 EEB08591.1 - 0.056 13.6 9.2 0.12 12.5 9.2 1.6 1 0 0 1 1 1 0 Tropomyosin like GntR PF00392.21 EEB08591.1 - 0.063 12.9 0.2 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 EEB08591.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FUR PF01475.19 EEB08591.1 - 0.069 13.3 1.6 0.086 13.0 0.1 1.9 2 0 0 2 2 2 0 Ferric uptake regulator family Cnn_1N PF07989.11 EEB08591.1 - 0.11 12.7 10.5 0.034 14.3 7.3 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Lzipper-MIP1 PF14389.6 EEB08591.1 - 0.11 12.8 7.4 4.3 7.7 0.2 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF812 PF05667.11 EEB08591.1 - 0.11 11.3 9.5 0.16 10.8 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_MT_bd PF06657.13 EEB08591.1 - 0.12 12.8 4.2 2.9 8.4 0.1 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4094 PF13334.6 EEB08591.1 - 0.17 12.3 3.0 0.14 12.6 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CENP-H PF05837.12 EEB08591.1 - 0.17 12.3 8.5 0.35 11.3 5.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) GAT PF03127.14 EEB08591.1 - 0.22 11.9 5.3 2.1 8.7 5.3 2.3 1 1 0 1 1 1 0 GAT domain DUF4972 PF16342.5 EEB08591.1 - 0.22 11.2 5.3 0.86 9.3 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) DUF1192 PF06698.11 EEB08591.1 - 0.37 10.9 2.6 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HU-CCDC81_bac_2 PF18175.1 EEB08591.1 - 0.89 9.5 5.2 5.6 6.9 0.0 3.1 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 bZIP_1 PF00170.21 EEB08591.1 - 1.8 8.7 9.0 5.8 7.1 2.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor MerR-DNA-bind PF09278.11 EEB08591.1 - 2 9.0 6.8 8.2 7.0 0.2 3.6 3 1 1 4 4 4 0 MerR, DNA binding DUF3573 PF12097.8 EEB08591.1 - 2.3 6.9 4.6 3.6 6.3 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) ZapB PF06005.12 EEB08591.1 - 4.8 7.7 18.8 33 5.0 13.3 3.3 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EEB08591.1 - 5.5 6.8 10.2 15 5.4 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator FapA PF03961.13 EEB08591.1 - 8.3 4.9 8.5 8.6 4.8 7.8 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A UCH PF00443.29 EEB08592.1 - 1.5e-51 175.4 1.5 1.9e-51 175.0 1.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB08592.1 - 3.3e-15 56.5 10.4 1.2e-13 51.4 1.3 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEB08592.1 - 5.7e-11 42.6 9.7 5.7e-11 42.6 9.7 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Pkinase PF00069.25 EEB08593.1 - 1.3e-70 237.8 0.0 2.2e-70 237.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08593.1 - 5e-49 166.9 0.0 9.1e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08593.1 - 1.2e-06 28.1 0.0 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEB08593.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEB08593.1 - 0.015 14.1 0.0 0.039 12.7 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEB08593.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF4695 PF15766.5 EEB08593.1 - 0.026 14.7 0.1 0.12 12.6 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Lgl_C PF08596.10 EEB08594.1 - 1.3e-56 192.1 0.0 1e-55 189.0 0.0 2.0 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Ribo_biogen_C PF04034.13 EEB08595.1 - 3.8e-52 175.3 0.0 4.9e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EEB08595.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.19 EEB08596.1 - 6e-43 146.1 0.0 1.5e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 EEB08596.1 - 1.8e-09 37.9 0.0 4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EEB08596.1 - 0.00012 22.3 1.4 0.00012 22.3 1.4 2.6 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EEB08596.1 - 0.00056 19.5 0.1 0.0017 17.9 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain Herpes_UL36 PF03586.13 EEB08596.1 - 0.061 12.6 0.4 0.13 11.6 0.4 1.6 1 1 0 1 1 1 0 Herpesvirus UL36 tegument protein Spc7 PF08317.11 EEB08597.1 - 8.3e-08 31.5 388.6 0.00044 19.2 15.2 16.3 3 3 14 17 17 17 11 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EEB08597.1 - 0.00013 22.0 19.7 0.00036 20.5 5.0 22.8 11 7 12 24 24 24 5 TolA binding protein trimerisation Filament PF00038.21 EEB08597.1 - 0.00015 21.5 20.1 0.00015 21.5 20.1 12.8 1 1 10 11 11 11 6 Intermediate filament protein DUF3584 PF12128.8 EEB08597.1 - 0.00026 18.7 56.4 0.00026 18.7 56.4 7.9 1 1 7 8 8 8 5 Protein of unknown function (DUF3584) DUF2968 PF11180.8 EEB08597.1 - 0.0035 17.0 14.3 0.0035 17.0 14.3 19.2 5 4 19 24 24 24 1 Protein of unknown function (DUF2968) DUF4201 PF13870.6 EEB08597.1 - 0.0038 17.0 16.3 0.0038 17.0 16.3 19.9 2 2 16 20 20 20 9 Domain of unknown function (DUF4201) UPF0242 PF06785.11 EEB08597.1 - 0.0045 17.1 18.6 0.0045 17.1 18.6 17.8 2 2 12 15 15 15 4 Uncharacterised protein family (UPF0242) N-terminus Turandot PF07240.11 EEB08597.1 - 2.3 8.3 6.2 3.1 7.8 1.2 4.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Taxilin PF09728.9 EEB08598.2 - 0.00063 19.0 7.6 0.0008 18.7 7.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TSC22 PF01166.18 EEB08598.2 - 0.0018 18.6 2.6 0.036 14.4 0.2 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family ATG16 PF08614.11 EEB08598.2 - 0.015 15.5 9.4 0.025 14.8 9.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EEB08598.2 - 0.022 14.5 2.1 0.029 14.1 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) TetR_C_26 PF17934.1 EEB08598.2 - 0.054 13.8 0.5 0.088 13.1 0.5 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GIT_CC PF16559.5 EEB08598.2 - 0.15 11.9 4.5 0.32 10.9 0.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 EEB08598.2 - 0.68 10.1 4.8 0.31 11.2 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EEB08598.2 - 1.2 9.6 11.0 87 3.7 11.0 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Fungal_TACC PF12709.7 EEB08598.2 - 1.5 9.3 13.8 0.64 10.5 4.1 2.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 EEB08598.2 - 9.6 6.9 8.9 27 5.4 0.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA His_Phos_1 PF00300.22 EEB08600.2 - 1.3e-35 122.8 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CheR PF01739.18 EEB08600.2 - 0.034 13.6 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FSH1 PF03959.13 EEB08601.1 - 7.4e-43 146.7 0.0 1.2e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Pur_DNA_glyco PF02245.16 EEB08601.1 - 0.029 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Dynein_attach_N PF15867.5 EEB08601.1 - 0.041 13.8 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Dynein attachment factor N-terminus TFIIS_C PF01096.18 EEB08602.1 - 1.3e-21 76.1 14.6 3e-20 71.8 3.4 3.0 2 1 0 2 2 2 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEB08602.1 - 3.8e-18 65.1 2.7 1.6e-16 59.8 0.5 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EEB08602.1 - 0.0017 18.2 7.8 0.21 11.6 1.6 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EEB08602.1 - 0.0017 17.8 6.6 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding zf-FPG_IleRS PF06827.14 EEB08602.1 - 0.015 15.1 1.6 0.015 15.1 1.6 1.9 3 0 0 3 3 1 0 Zinc finger found in FPG and IleRS UPF0547 PF10571.9 EEB08602.1 - 0.041 14.0 10.1 1.4 9.1 0.6 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 IBR PF01485.21 EEB08602.1 - 0.076 13.3 7.2 0.53 10.5 0.3 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 EEB08602.1 - 0.087 12.3 0.1 0.087 12.3 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 EEB08602.1 - 0.14 11.8 3.6 2.4 7.9 0.1 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Elf1 PF05129.13 EEB08602.1 - 0.14 12.2 2.7 1.2 9.2 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 EEB08602.1 - 0.2 11.7 8.5 0.71 9.9 1.0 2.7 2 2 0 2 2 2 0 Double zinc ribbon Desulfoferrod_N PF06397.12 EEB08602.1 - 0.26 10.9 4.0 8 6.2 0.6 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Nudix_N_2 PF14803.6 EEB08602.1 - 0.27 11.2 5.7 1 9.3 1.4 2.6 2 1 0 2 2 2 0 Nudix N-terminal NOB1_Zn_bind PF08772.11 EEB08602.1 - 0.75 10.0 4.5 0.57 10.4 1.3 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 EEB08602.1 - 0.81 9.3 5.8 11 5.8 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 EEB08602.1 - 0.9 8.9 4.6 2.6 7.4 1.5 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-Mss51 PF13824.6 EEB08602.1 - 0.98 9.6 6.4 4.9 7.3 0.5 2.7 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_11 PF16622.5 EEB08602.1 - 0.98 9.2 5.8 7.2 6.5 0.0 2.6 3 0 0 3 3 2 0 zinc-finger C2H2-type OrfB_Zn_ribbon PF07282.11 EEB08602.1 - 2.1 8.3 6.5 3.5 7.6 0.6 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 EEB08602.1 - 3.8 7.7 10.5 8.3 6.6 1.0 3.7 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EEB08602.1 - 4.4 7.1 13.8 1.1 9.1 0.4 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF3797 PF12677.7 EEB08602.1 - 4.5 7.2 8.2 4.5 7.2 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) zinc_ribbon_10 PF10058.9 EEB08602.1 - 5.5 6.8 9.2 12 5.8 1.6 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein C1_2 PF03107.16 EEB08602.1 - 5.6 7.4 11.2 2.5 8.5 0.1 3.1 2 1 1 3 3 3 0 C1 domain PhnA_Zn_Ribbon PF08274.12 EEB08602.1 - 8.1 6.5 8.4 1.8 8.6 0.1 2.7 3 0 0 3 3 2 0 PhnA Zinc-Ribbon Ribosomal_S8 PF00410.19 EEB08603.1 - 4.4e-23 81.6 0.4 7.3e-23 80.9 0.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Asp_protease PF09668.10 EEB08604.1 - 9.6e-56 186.9 0.0 2.8e-55 185.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF2781 PF10914.8 EEB08604.1 - 1.6e-45 155.1 9.1 2.7e-45 154.4 9.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) gag-asp_proteas PF13975.6 EEB08604.1 - 1.8e-21 76.5 0.0 3.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EEB08604.1 - 9e-10 39.1 0.1 2.4e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 EEB08604.1 - 2.3e-06 27.4 0.0 5.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EEB08604.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease SPC25 PF06703.11 EEB08604.1 - 0.035 13.9 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_A2B PF12384.8 EEB08604.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase DIE2_ALG10 PF04922.12 EEB08605.2 - 8.5e-42 143.8 0.2 1e-41 143.5 0.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family dCMP_cyt_deam_1 PF00383.23 EEB08608.2 - 7.3e-25 86.8 2.0 7.3e-25 86.8 2.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEB08608.2 - 8.7e-11 41.7 0.3 1.7e-10 40.8 0.3 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EEB08608.2 - 0.081 13.0 0.7 0.88 9.7 0.2 2.4 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 FtsJ PF01728.19 EEB08610.2 - 2.3e-52 177.7 0.0 2.7e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EEB08610.2 - 0.00027 20.8 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08610.2 - 0.063 14.0 0.1 0.36 11.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08610.2 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Rft-1 PF04506.13 EEB08611.1 - 6.8e-120 401.2 19.8 8.4e-120 400.9 19.8 1.0 1 0 0 1 1 1 1 Rft protein His_biosynth PF00977.21 EEB08612.1 - 5.4e-46 156.9 0.0 1.4e-45 155.5 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EEB08612.1 - 8.8e-22 77.8 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EEB08612.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EEB08612.1 - 1.4e-05 25.1 0.0 0.0063 16.4 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Dus PF01207.17 EEB08612.1 - 0.02 14.0 0.0 0.043 12.9 0.0 1.5 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 EEB08612.1 - 0.033 13.9 0.1 0.31 10.8 0.1 2.3 1 1 0 1 1 1 0 Peptidase C26 SOR_SNZ PF01680.17 EEB08612.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family DJ-1_PfpI PF01965.24 EEB08612.1 - 0.15 11.9 0.0 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 DJ-1/PfpI family SAGA-Tad1 PF12767.7 EEB08613.2 - 8.4e-38 130.4 0.3 1.4e-37 129.7 0.1 1.4 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Xan_ur_permease PF00860.20 EEB08614.2 - 4e-24 85.1 27.2 4e-24 85.1 27.2 2.4 2 1 0 2 2 2 1 Permease family FA_hydroxylase PF04116.13 EEB08616.2 - 2.5e-23 82.9 14.3 2.5e-23 82.9 14.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PIF1 PF05970.14 EEB08617.2 - 1.6e-61 208.5 0.9 4.9e-48 164.1 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EEB08617.2 - 3.9e-22 78.9 0.0 6.9e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB08617.2 - 1.1e-11 45.3 0.0 2.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEB08617.2 - 3.6e-07 30.5 0.0 1.4e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EEB08617.2 - 1.8e-05 22.9 0.0 0.00021 19.4 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 EEB08617.2 - 7.7e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EEB08617.2 - 0.0001 22.2 0.6 0.17 11.6 0.3 3.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EEB08617.2 - 0.00018 21.9 0.3 0.0011 19.4 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EEB08617.2 - 0.00042 19.8 0.0 0.001 18.5 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 EEB08617.2 - 0.00043 20.1 0.9 0.00071 19.3 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 EEB08617.2 - 0.00067 19.5 0.1 0.036 13.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 EEB08617.2 - 0.00088 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EEB08617.2 - 0.0057 17.1 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EEB08617.2 - 0.0097 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EEB08617.2 - 0.014 14.6 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 EEB08617.2 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2075 PF09848.9 EEB08617.2 - 0.024 13.9 0.1 0.095 11.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EEB08617.2 - 0.025 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 EEB08617.2 - 0.029 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EEB08617.2 - 0.043 13.7 0.6 0.25 11.3 0.2 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EEB08617.2 - 0.047 14.1 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.14 EEB08617.2 - 0.047 13.5 0.5 0.31 10.9 0.5 2.3 1 1 0 1 1 1 0 Helicase AAA_14 PF13173.6 EEB08617.2 - 0.047 13.7 0.3 0.8 9.7 0.1 2.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EEB08617.2 - 0.051 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 EEB08617.2 - 0.06 12.2 0.2 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 EEB08617.2 - 0.069 13.2 1.1 1.2 9.1 1.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EEB08617.2 - 0.098 12.6 0.2 0.39 10.6 0.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EEB08617.2 - 0.13 12.8 0.1 0.8 10.2 0.0 2.6 1 1 1 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EEB08617.2 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SH3_13 PF18335.1 EEB08617.2 - 0.13 12.1 0.1 0.44 10.4 0.1 1.9 2 0 0 2 2 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Pex19 PF04614.12 EEB08618.2 - 3e-24 86.2 10.1 3.9e-24 85.8 10.1 1.1 1 0 0 1 1 1 1 Pex19 protein family CREPT PF16566.5 EEB08618.2 - 0.022 14.9 7.7 0.12 12.5 1.6 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Type_III_YscX PF09474.10 EEB08618.2 - 0.24 11.7 2.6 0.65 10.3 0.9 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) PhnI PF05861.12 EEB08618.2 - 0.81 8.5 2.9 0.8 8.5 1.3 1.7 1 1 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnI) GET2 PF08690.10 EEB08618.2 - 0.84 9.3 10.8 1.8 8.2 10.8 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 CIA30 PF08547.12 EEB08620.1 - 1e-37 129.6 0.1 1.1e-37 129.5 0.1 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Snf7 PF03357.21 EEB08621.1 - 3.1e-21 75.7 8.8 3.9e-21 75.4 8.8 1.1 1 0 0 1 1 1 1 Snf7 GAT PF03127.14 EEB08621.1 - 0.095 13.0 2.6 0.13 12.6 0.1 2.4 2 1 0 2 2 2 0 GAT domain DUF4140 PF13600.6 EEB08621.1 - 8.9 6.8 7.9 3.4 8.2 0.5 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CS PF04969.16 EEB08622.1 - 6.4e-06 27.1 0.4 1.1e-05 26.3 0.4 1.3 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.27 EEB08623.1 - 3e-49 167.1 0.0 2.4e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EEB08623.1 - 4.4e-40 138.1 41.9 3.1e-21 76.2 19.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EEB08623.1 - 2.6e-10 40.1 0.1 0.00087 18.8 0.2 4.0 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EEB08623.1 - 2.9e-08 33.5 0.2 0.038 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEB08623.1 - 2.7e-07 31.1 0.0 0.048 14.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EEB08623.1 - 1e-06 28.8 2.8 0.16 11.7 0.0 4.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB08623.1 - 1.1e-06 28.3 0.6 0.046 13.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEB08623.1 - 3.6e-05 24.1 1.0 0.33 11.2 0.1 3.4 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 EEB08623.1 - 4.4e-05 22.7 0.1 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EEB08623.1 - 7.2e-05 22.9 0.3 0.59 10.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 EEB08623.1 - 9.5e-05 22.2 0.0 0.41 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEB08623.1 - 0.0002 21.3 0.1 0.094 12.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EEB08623.1 - 0.00023 21.3 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin family Roc PF08477.13 EEB08623.1 - 0.00032 20.9 0.3 0.25 11.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EEB08623.1 - 0.00054 19.5 0.8 0.27 10.7 0.0 2.7 2 0 0 2 2 2 1 Poxvirus A32 protein DUF87 PF01935.17 EEB08623.1 - 0.00087 19.4 1.4 0.0057 16.8 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain ATPase PF06745.13 EEB08623.1 - 0.0015 18.0 0.8 0.29 10.5 0.1 2.4 2 0 0 2 2 2 1 KaiC Septin PF00735.18 EEB08623.1 - 0.0025 17.1 0.1 0.45 9.7 0.0 2.4 2 0 0 2 2 2 1 Septin IstB_IS21 PF01695.17 EEB08623.1 - 0.0027 17.5 0.2 3.1 7.5 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 EEB08623.1 - 0.0035 17.3 0.6 2.4 8.0 0.2 3.0 2 0 0 2 2 2 1 NACHT domain Ras PF00071.22 EEB08623.1 - 0.0054 16.4 0.6 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.18 EEB08623.1 - 0.0054 16.1 0.2 0.67 9.3 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EEB08623.1 - 0.0065 16.0 0.5 2.9 7.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EEB08623.1 - 0.023 14.0 0.1 7.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 EEB08623.1 - 0.034 13.9 0.1 5.5 6.7 0.3 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 EEB08623.1 - 0.035 14.5 0.3 13 6.2 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EEB08623.1 - 0.039 14.1 2.3 3.8 7.7 0.2 2.7 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 EEB08623.1 - 0.04 14.0 2.8 0.89 9.6 0.0 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 EEB08623.1 - 0.051 14.1 1.0 6.3 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEB08623.1 - 0.077 12.7 0.4 19 4.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EEB08623.1 - 0.091 12.5 0.0 4.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 EEB08623.1 - 0.093 11.9 0.3 0.82 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EEB08623.1 - 0.14 12.2 0.7 11 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EEB08623.1 - 0.15 11.4 0.1 13 5.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 EEB08623.1 - 0.21 10.8 1.6 15 4.7 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain Aldedh PF00171.22 EEB08624.1 - 8.6e-185 614.6 0.1 9.7e-185 614.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EEB08624.1 - 0.18 11.2 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Bromodomain PF00439.25 EEB08625.2 - 8.9e-27 93.0 0.5 1.8e-21 76.0 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EEB08625.2 - 2.7e-21 75.7 0.1 6.4e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 BAH domain eIF2A PF08662.11 EEB08626.1 - 1.4e-78 263.2 0.3 8.4e-78 260.7 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EEB08626.1 - 0.0025 18.6 0.0 0.77 10.7 0.0 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.6 EEB08626.1 - 0.23 12.0 1.4 0.35 11.4 0.1 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 CLP1_P PF16575.5 EEB08627.1 - 9.2e-36 123.4 0.0 1.9e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 EEB08627.1 - 0.0022 18.4 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 EEB08627.1 - 0.0028 17.7 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEB08627.1 - 0.0053 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EEB08627.1 - 0.012 16.2 0.0 0.033 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEB08627.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EEB08627.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEB08627.1 - 0.029 14.3 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 EEB08627.1 - 0.04 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB08627.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EEB08627.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 EEB08627.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EEB08627.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_transf_34 PF05637.12 EEB08628.1 - 4.6e-77 259.0 0.9 5.5e-77 258.7 0.9 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 EEB08628.1 - 0.051 13.6 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase EPL1 PF10513.9 EEB08630.2 - 5.5e-15 56.1 0.3 1.1e-14 55.2 0.3 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF4298 PF14131.6 EEB08630.2 - 0.064 13.2 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) EF-hand_1 PF00036.32 EEB08631.1 - 1.8e-23 80.3 10.3 9.6e-07 27.9 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EEB08631.1 - 5.1e-21 74.9 7.1 9.4e-14 51.6 1.9 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEB08631.1 - 1.2e-18 65.4 6.2 4e-05 23.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EEB08631.1 - 5e-17 60.5 11.8 5.9e-05 22.4 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EEB08631.1 - 6e-12 45.2 10.6 0.0008 19.2 0.7 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EEB08631.1 - 1.1e-07 32.2 0.1 0.0047 17.2 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EEB08631.1 - 0.00043 20.2 6.5 0.85 9.6 0.6 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand DnaJ_C PF01556.18 EEB08632.1 - 8.2e-41 139.5 0.0 1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEB08632.1 - 1.6e-25 89.0 1.3 2.5e-25 88.4 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain TB2_DP1_HVA22 PF03134.19 EEB08633.2 - 2.5e-26 91.4 8.1 2.5e-26 91.4 8.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CCDC53 PF10152.9 EEB08633.2 - 0.17 12.3 0.0 0.28 11.6 0.0 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex OAD_gamma PF04277.13 EEB08633.2 - 0.58 10.8 3.3 6.9 7.3 0.4 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RNase_P_Rpp14 PF01900.19 EEB08634.1 - 1e-36 125.3 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Ham1p_like PF01725.16 EEB08635.2 - 1.3e-52 178.4 0.0 1.5e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EEB08636.1 - 8.1e-30 104.0 0.1 1.2e-29 103.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEB08636.1 - 2.2e-07 31.1 0.1 3.7e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EEB08636.1 - 2.6e-07 31.1 0.0 5.9e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEB08636.1 - 4.7e-06 26.9 0.3 1e-05 25.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEB08636.1 - 2.9e-05 23.7 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 EEB08636.1 - 5.7e-05 23.6 0.0 0.00012 22.5 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEB08636.1 - 0.00016 21.9 0.0 0.00043 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EEB08636.1 - 0.00017 21.5 0.0 0.00088 19.2 0.0 1.9 2 0 0 2 2 2 1 NTPase ADK PF00406.22 EEB08636.1 - 0.00036 20.7 0.0 0.018 15.2 0.0 2.3 1 1 0 2 2 2 1 Adenylate kinase AAA_5 PF07728.14 EEB08636.1 - 0.00058 19.9 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MobB PF03205.14 EEB08636.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EEB08636.1 - 0.0013 19.0 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 EEB08636.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EEB08636.1 - 0.0026 17.8 0.0 0.0093 16.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EEB08636.1 - 0.0028 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EEB08636.1 - 0.0031 17.3 0.1 0.0059 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EEB08636.1 - 0.0039 17.3 0.2 0.016 15.3 0.2 1.9 1 1 0 1 1 1 1 Shikimate kinase NACHT PF05729.12 EEB08636.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.18 EEB08636.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family TsaE PF02367.17 EEB08636.1 - 0.012 15.6 1.5 0.032 14.2 0.3 2.1 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EEB08636.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 EEB08636.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Hydin_ADK PF17213.3 EEB08636.1 - 0.016 15.5 0.3 0.033 14.5 0.1 1.6 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 EEB08636.1 - 0.02 14.5 0.1 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EEB08636.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 EEB08636.1 - 0.023 14.4 0.1 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 EEB08636.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EEB08636.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 EEB08636.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.19 EEB08636.1 - 0.029 14.2 0.3 0.24 11.2 0.0 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase Parvo_NS1 PF01057.17 EEB08636.1 - 0.036 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EEB08636.1 - 0.038 13.2 0.1 0.085 12.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EEB08636.1 - 0.039 13.2 0.3 0.064 12.5 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EEB08636.1 - 0.041 14.2 0.2 0.094 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.22 EEB08636.1 - 0.046 13.3 0.1 0.1 12.2 0.0 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EEB08636.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEB08636.1 - 0.054 14.0 0.1 0.13 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 EEB08636.1 - 0.059 12.4 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.11 EEB08636.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 EEB08636.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family Roc PF08477.13 EEB08636.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EEB08636.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 EEB08636.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 EEB08636.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SRPRB PF09439.10 EEB08636.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.9 EEB08636.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.4 2 0 0 2 2 1 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 EEB08636.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 EEB08636.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RsgA_GTPase PF03193.16 EEB08636.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Cytidylate_kin PF02224.18 EEB08636.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 EEB08636.1 - 0.21 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 EEB08637.1 - 1.6e-63 214.6 0.0 1e-54 185.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08637.1 - 2.5e-35 122.0 0.0 2e-32 112.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB08637.1 - 3e-12 46.5 0.0 2e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEB08637.1 - 7.9e-08 31.5 0.1 2.2e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEB08637.1 - 0.00065 19.7 0.1 0.0026 17.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEB08637.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EEB08637.1 - 0.023 14.3 0.3 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EEB08637.1 - 0.12 11.8 0.2 0.27 10.6 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIG-X PF08320.12 EEB08639.1 - 6.5e-43 147.1 0.1 9.6e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DUF2804 PF10974.8 EEB08639.1 - 0.14 11.6 0.0 0.56 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2804) AMPK1_CBM PF16561.5 EEB08640.1 - 1.4e-30 105.3 0.1 2.8e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EEB08640.1 - 2.3e-24 85.4 3.5 2.3e-24 85.4 3.5 2.7 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain FAD-oxidase_C PF02913.19 EEB08642.1 - 1e-64 218.6 0.0 1.5e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEB08642.1 - 2.7e-38 130.8 0.1 5.1e-38 130.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain TPR_2 PF07719.17 EEB08643.1 - 3e-28 95.6 50.8 2.1e-05 24.3 0.4 17.0 20 0 0 20 20 17 8 Tetratricopeptide repeat TPR_1 PF00515.28 EEB08643.1 - 8.6e-28 95.0 28.0 6.2e-05 22.6 0.1 14.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08643.1 - 1.3e-27 96.1 24.7 1.7e-05 25.2 0.2 11.1 7 5 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 EEB08643.1 - 5.4e-25 87.8 33.4 5.1e-06 27.0 0.6 12.4 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 EEB08643.1 - 5.3e-20 69.9 43.6 0.015 15.5 0.1 15.4 17 1 0 17 17 14 6 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08643.1 - 1.2e-19 69.3 42.5 0.0019 18.8 0.2 16.0 11 4 6 17 17 16 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEB08643.1 - 6e-15 55.3 42.5 7e-05 23.0 1.0 11.0 10 3 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EEB08643.1 - 4.8e-12 45.4 35.1 0.0013 18.3 0.0 15.3 16 3 3 19 19 17 3 TPR repeat TPR_7 PF13176.6 EEB08643.1 - 7.8e-12 44.3 29.6 0.25 11.5 0.0 12.7 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEB08643.1 - 1.5e-11 43.8 29.8 0.63 10.6 0.1 13.4 16 0 0 16 16 12 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEB08643.1 - 1.2e-07 31.8 14.8 0.033 14.3 0.1 9.4 10 2 1 12 12 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB08643.1 - 4.9e-07 29.9 34.4 0.00021 21.5 0.6 8.8 9 1 0 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EEB08643.1 - 2.3e-05 24.7 12.5 0.44 10.9 0.1 6.7 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08643.1 - 3.8e-05 23.4 21.3 3.2 7.8 0.1 10.7 12 1 0 12 12 11 1 Tetratricopeptide repeat TPR_4 PF07721.14 EEB08643.1 - 0.00055 20.3 9.6 4.7 8.1 0.3 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEB08643.1 - 0.013 14.8 11.6 0.027 13.7 0.5 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EEB08643.1 - 0.018 13.8 2.7 5.6 5.6 0.0 3.8 2 1 2 4 4 4 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 EEB08643.1 - 0.022 15.2 20.5 0.36 11.2 2.9 5.8 5 1 2 7 7 6 0 Bacterial transcriptional activator domain TPR_22 PF18833.1 EEB08643.1 - 0.024 14.8 0.6 0.14 12.3 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 EEB08643.1 - 0.055 13.5 1.5 2.3 8.3 0.1 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) DUF2225 PF09986.9 EEB08643.1 - 0.17 11.6 6.0 0.11 12.2 1.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 EEB08643.1 - 0.41 11.4 24.2 67 4.5 0.0 11.7 14 0 0 14 14 13 0 Tetratricopeptide repeat HEPN PF05168.14 EEB08643.1 - 0.43 10.7 5.1 13 6.0 0.3 4.3 4 0 0 4 4 4 0 HEPN domain HEAT_2 PF13646.6 EEB08643.1 - 0.6 10.5 3.2 1.5 9.3 0.3 3.2 2 1 0 3 3 2 0 HEAT repeats Fis1_TPR_C PF14853.6 EEB08643.1 - 1.7 8.8 14.3 5.5 7.1 0.1 6.6 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EEB08643.1 - 1.8 8.7 10.7 41 4.4 0.0 5.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SNF2_N PF00176.23 EEB08644.2 - 8.6e-72 241.8 0.2 2.3e-71 240.3 0.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB08644.2 - 3.8e-21 75.5 0.0 8.2e-19 68.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EEB08644.2 - 3.5e-20 71.9 0.8 1.2e-19 70.1 0.8 2.0 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 EEB08644.2 - 2.3e-15 56.0 5.0 6.1e-15 54.7 5.0 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 EEB08644.2 - 7e-09 35.9 0.1 2.9e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SnAC PF14619.6 EEB08644.2 - 1.5e-05 25.5 4.5 1.5e-05 25.5 4.5 2.5 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex DUF3734 PF12536.8 EEB08644.2 - 0.028 14.8 0.2 0.028 14.8 0.2 2.8 3 0 0 3 3 3 0 Patatin phospholipase Shugoshin_C PF07557.11 EEB08644.2 - 0.036 13.9 0.3 0.078 12.8 0.3 1.6 1 0 0 1 1 1 0 Shugoshin C terminus DUF4184 PF13803.6 EEB08644.2 - 0.2 11.3 0.1 0.36 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) PDT PF00800.18 EEB08644.2 - 0.78 9.5 6.3 5.5 6.7 1.6 2.8 2 0 0 2 2 2 0 Prephenate dehydratase His_Phos_1 PF00300.22 EEB08645.1 - 2.2e-34 118.9 0.0 2.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 EEB08646.2 - 7.5e-24 84.3 26.4 7.5e-24 84.3 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB08646.2 - 7.2e-06 25.1 3.5 7.2e-06 25.1 3.5 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter ANAPC4_WD40 PF12894.7 EEB08647.1 - 2.7e-15 56.4 0.4 7.2e-07 29.4 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB08647.1 - 4.2e-09 36.9 6.0 0.011 16.6 0.3 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EEB08647.1 - 5.2e-05 22.4 0.0 0.0046 16.0 0.0 2.6 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EEB08647.1 - 0.00013 21.9 0.1 0.11 12.4 0.0 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EEB08647.1 - 0.00019 20.9 0.0 0.041 13.2 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain Nbas_N PF15492.6 EEB08647.1 - 0.029 13.7 0.1 0.14 11.4 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 EEB08647.1 - 0.15 10.0 0.0 2 6.3 0.0 2.4 2 1 1 3 3 3 0 IKI3 family PQQ_3 PF13570.6 EEB08647.1 - 0.89 10.1 2.7 12 6.6 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain PPTA PF01239.22 EEB08648.2 - 3.7e-39 131.3 18.1 3.8e-08 32.8 0.4 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DFF-C PF09033.10 EEB08648.2 - 0.051 13.5 1.8 2 8.3 0.1 2.9 3 0 0 3 3 3 0 DNA Fragmentation factor 45kDa, C terminal domain Pribosyltran_N PF13793.6 EEB08649.1 - 5.3e-49 165.0 0.5 6.6e-48 161.5 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEB08649.1 - 1.2e-46 159.1 3.9 4.2e-40 137.7 3.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EEB08649.1 - 2.8e-17 62.7 2.2 1.4e-16 60.4 1.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEB08649.1 - 0.01 15.3 0.2 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase zinc_ribbon_10 PF10058.9 EEB08650.2 - 2.4e-17 62.4 0.5 4.4e-17 61.5 0.5 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein ATP-grasp_2 PF08442.10 EEB08651.2 - 2.7e-74 249.1 0.3 5.4e-74 248.1 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EEB08651.2 - 6.8e-24 84.4 0.3 1.1e-23 83.8 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EEB08651.2 - 0.00012 21.6 0.2 0.00042 19.9 0.2 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EEB08651.2 - 0.0012 18.6 0.0 0.0082 15.9 0.0 2.2 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EEB08651.2 - 0.022 14.5 0.2 1.5 8.6 0.1 2.6 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain HSP20 PF00011.21 EEB08653.1 - 4.4e-21 74.9 0.4 5.3e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EEB08653.1 - 6e-11 41.7 0.0 9.3e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EEB08653.1 - 0.0069 17.4 0.1 0.015 16.3 0.0 1.5 1 1 0 1 1 1 1 CS domain BON PF04972.17 EEB08653.1 - 0.032 14.5 0.2 0.091 13.1 0.4 1.7 2 0 0 2 2 2 0 BON domain PIH1_CS PF18201.1 EEB08653.1 - 0.053 13.9 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 PIH1 CS-like domain Lung_7-TM_R PF06814.13 EEB08654.1 - 3.5e-12 46.2 4.5 4.9e-12 45.7 4.5 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor MFS_1 PF07690.16 EEB08655.1 - 1.6e-34 119.4 23.0 1.6e-34 119.4 23.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB08655.1 - 2.3e-11 43.2 6.6 2.3e-11 43.2 6.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EEB08655.1 - 5.5e-05 22.6 0.9 5.5e-05 22.6 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EEB08655.1 - 0.00027 19.4 2.9 0.00027 19.4 2.9 2.1 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EEB08655.1 - 0.0023 16.4 1.0 0.004 15.6 1.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.16 EEB08655.1 - 0.0039 16.9 1.7 0.0039 16.9 1.7 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Aldose_epim PF01263.20 EEB08656.1 - 1.5e-66 224.8 0.2 2.3e-66 224.2 0.2 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 EEB08656.1 - 1e-55 189.5 0.0 1.4e-55 189.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEB08656.1 - 1.5e-51 175.2 0.0 3e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEB08656.1 - 1.8e-16 60.0 0.1 3e-16 59.3 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EEB08656.1 - 4.9e-15 55.4 0.0 8.9e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEB08656.1 - 6.8e-15 55.0 0.0 1.4e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EEB08656.1 - 8e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEB08656.1 - 6.6e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EEB08656.1 - 4.9e-05 22.9 0.0 0.00012 21.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EEB08656.1 - 0.00016 21.0 0.0 0.022 13.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 EEB08656.1 - 0.00026 20.6 0.5 0.00057 19.5 0.5 1.6 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EEB08656.1 - 0.1 12.2 0.4 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.24 EEB08657.1 - 4.6e-119 398.2 26.0 5.3e-119 398.0 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB08657.1 - 5.1e-21 75.0 29.3 3.1e-15 56.0 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 EEB08658.1 - 7.1e-61 206.0 0.0 5.3e-59 199.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fe-ADH PF00465.19 EEB08659.1 - 1.5e-125 418.8 5.5 1.7e-125 418.6 5.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEB08659.1 - 7.3e-26 91.4 5.8 1.2e-12 48.1 0.2 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1967 PF09269.11 EEB08659.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Glyco_hydro_31 PF01055.26 EEB08660.1 - 1.6e-147 492.3 9.3 2.4e-147 491.7 9.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EEB08660.1 - 3.2e-31 107.9 0.1 7.8e-31 106.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EEB08660.1 - 2.2e-05 24.7 0.3 8.3e-05 22.8 0.3 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like zf-A20 PF01754.16 EEB08660.1 - 0.092 12.7 1.3 0.75 9.8 0.2 2.5 2 0 0 2 2 2 0 A20-like zinc finger Methyltransf_31 PF13847.6 EEB08661.1 - 7.6e-33 113.4 0.0 1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08661.1 - 8.5e-21 74.5 0.0 1.4e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB08661.1 - 1.2e-18 67.5 0.0 2.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08661.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08661.1 - 2.5e-14 53.8 0.0 3.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EEB08661.1 - 9.3e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EEB08661.1 - 4.1e-10 39.5 0.0 6.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EEB08661.1 - 2.4e-09 36.9 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EEB08661.1 - 5.5e-09 35.7 0.1 8.2e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EEB08661.1 - 8.8e-09 35.2 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EEB08661.1 - 4.1e-07 29.8 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 EEB08661.1 - 1.1e-06 28.1 0.0 1.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EEB08661.1 - 1.6e-06 27.7 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EEB08661.1 - 8.7e-06 24.9 0.0 1.8e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) GidB PF02527.15 EEB08661.1 - 1.6e-05 24.3 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 EEB08661.1 - 2.7e-05 23.9 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NodS PF05401.11 EEB08661.1 - 3.3e-05 23.6 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.18 EEB08661.1 - 3.6e-05 23.5 2.6 0.0004 20.1 2.6 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 EEB08661.1 - 4.2e-05 23.2 0.0 6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EEB08661.1 - 5.7e-05 23.1 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EEB08661.1 - 0.00011 22.2 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EEB08661.1 - 0.00026 20.6 0.2 0.012 15.1 0.1 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 EEB08661.1 - 0.0004 20.5 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EEB08661.1 - 0.00059 19.6 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DREV PF05219.12 EEB08661.1 - 0.0007 18.8 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 EEB08661.1 - 0.0051 15.8 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 EEB08661.1 - 0.0087 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 EEB08661.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Met_10 PF02475.16 EEB08661.1 - 0.019 14.7 0.0 0.042 13.6 0.1 1.5 2 0 0 2 2 1 0 Met-10+ like-protein RrnaAD PF00398.20 EEB08661.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.17 EEB08661.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase GLEYA PF10528.9 EEB08662.1 - 2.4e-17 63.1 1.7 8.6e-17 61.4 0.2 2.8 2 0 0 2 2 2 1 GLEYA domain AA_permease PF00324.21 EEB08663.1 - 9.6e-112 374.0 40.2 1.2e-111 373.7 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB08663.1 - 8.7e-30 103.9 42.7 1.1e-29 103.5 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease Gp_dh_C PF02800.20 EEB08664.1 - 9.1e-72 239.8 0.1 1.3e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEB08664.1 - 4e-40 136.2 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEB08664.1 - 0.028 14.5 1.6 0.1 12.7 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EEB08664.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3576 PF12100.8 EEB08664.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) AA_permease PF00324.21 EEB08665.1 - 3.2e-116 388.8 37.5 4e-116 388.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB08665.1 - 1.4e-33 116.4 40.4 1.8e-33 116.0 40.4 1.2 1 0 0 1 1 1 1 Amino acid permease Transport_MerF PF11431.8 EEB08665.1 - 0.16 11.9 3.9 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Membrane transport protein MerF DUF4118 PF13493.6 EEB08665.1 - 8.1 6.3 10.3 2.3 8.1 4.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) zf-RING_2 PF13639.6 EEB08667.1 - 7.3e-13 48.6 10.4 1.1e-12 48.0 10.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EEB08667.1 - 2.7e-09 37.2 7.4 5.7e-09 36.1 7.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEB08667.1 - 1.6e-08 34.3 8.7 2.5e-08 33.6 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEB08667.1 - 1.3e-07 31.2 5.9 2.6e-07 30.3 5.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EEB08667.1 - 2.6e-06 27.4 1.8 5.4e-06 26.4 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EEB08667.1 - 1.7e-05 24.6 9.6 2.8e-05 23.9 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB08667.1 - 5.3e-05 23.1 9.8 8.5e-05 22.4 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEB08667.1 - 0.00018 21.3 7.3 0.00034 20.4 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEB08667.1 - 0.0012 18.6 7.1 0.002 18.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEB08667.1 - 0.0056 16.3 5.2 0.0091 15.6 5.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EEB08667.1 - 0.026 14.5 8.4 0.056 13.5 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 EEB08667.1 - 0.045 13.6 3.7 0.088 12.6 3.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EEB08667.1 - 0.098 13.0 9.1 0.16 12.3 9.1 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EEB08667.1 - 0.16 12.2 10.1 0.28 11.3 10.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EEB08667.1 - 0.2 11.7 2.0 0.42 10.7 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EEB08667.1 - 0.51 10.6 5.9 1.1 9.4 5.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EEB08667.1 - 2.5 7.9 7.5 5.3 6.9 7.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EEB08667.1 - 4.2 7.4 6.8 3 7.8 4.4 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EEB08667.1 - 8.4 6.6 8.8 84 3.5 8.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SMC_N PF02463.19 EEB08668.1 - 2.7e-69 233.0 0.7 1.1e-68 231.0 0.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEB08668.1 - 1.3e-21 77.1 0.2 7.6e-20 71.4 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEB08668.1 - 2.5e-12 47.2 5.6 4e-05 23.6 0.1 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEB08668.1 - 1.3e-11 45.4 14.0 1.3e-11 45.4 14.0 6.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 EEB08668.1 - 6.8e-05 22.5 0.1 0.00019 21.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 EEB08668.1 - 0.0046 17.1 6.6 0.0046 17.1 6.6 8.1 3 2 3 7 7 7 1 Tropomyosin like PhoU PF01895.19 EEB08668.1 - 0.019 15.4 1.5 0.019 15.4 1.5 6.0 6 3 1 7 7 7 0 PhoU domain DUF4382 PF14321.6 EEB08668.1 - 2 8.7 6.6 0.37 11.0 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) TraF_2 PF13729.6 EEB08668.1 - 8.6 5.6 15.5 4.2 6.7 0.0 4.4 4 1 0 4 4 4 0 F plasmid transfer operon, TraF, protein UbiA PF01040.18 EEB08669.1 - 0.024 13.9 1.0 0.1 11.9 0.1 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family GCP_C_terminal PF04130.13 EEB08670.1 - 2.9e-62 210.9 9.9 2.9e-62 210.9 9.9 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EEB08670.1 - 6.2e-59 200.1 0.7 3.4e-58 197.7 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ran_BP1 PF00638.18 EEB08671.2 - 2.1e-19 70.0 0.2 5.2e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 RanBP1 domain YfhO PF09586.10 EEB08671.2 - 2.7 6.1 6.7 3.1 5.9 6.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4769 PF15992.5 EEB08671.2 - 8.2 6.1 12.9 2.9 7.6 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) Ish1 PF10281.9 EEB08672.1 - 4.1e-51 171.0 36.6 2.3e-10 40.6 1.2 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EEB08672.1 - 1.8e-10 40.3 0.0 0.096 12.5 0.0 6.4 6 0 0 6 6 6 2 SAP domain HeH PF12949.7 EEB08672.1 - 8.4e-06 25.4 0.0 0.033 13.9 0.0 4.7 6 0 0 6 6 6 1 HeH/LEM domain LEA_4 PF02987.16 EEB08672.1 - 0.0014 18.7 4.1 0.0014 18.7 4.1 3.4 3 0 0 3 3 3 1 Late embryogenesis abundant protein LEM PF03020.15 EEB08672.1 - 0.0025 17.4 0.0 0.6 9.7 0.0 3.8 3 0 0 3 3 3 1 LEM domain RsbRD_N PF14361.6 EEB08672.1 - 0.005 17.5 2.4 3.8 8.3 0.3 3.8 4 0 0 4 4 4 1 RsbT co-antagonist protein rsbRD N-terminal domain Phasin PF05597.11 EEB08672.1 - 0.0051 16.8 15.6 0.45 10.5 1.8 4.4 3 2 1 4 4 4 2 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 EEB08672.1 - 0.0071 16.9 21.0 0.39 11.3 2.0 5.3 4 2 0 4 4 4 1 YtxH-like protein ApoO PF09769.9 EEB08672.1 - 0.027 14.4 4.6 20 5.1 0.0 5.0 4 1 1 5 5 5 0 Apolipoprotein O Neur_chan_memb PF02932.16 EEB08672.1 - 0.29 11.1 5.0 0.72 9.9 3.4 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF883 PF05957.13 EEB08672.1 - 0.38 11.4 19.7 3.8 8.2 2.9 5.0 5 1 1 6 6 5 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 EEB08672.1 - 2.6 7.9 11.5 2.2 8.1 0.4 4.0 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain SAM_2 PF07647.17 EEB08672.1 - 10 6.4 8.9 34 4.7 0.2 4.9 6 0 0 6 6 5 0 SAM domain (Sterile alpha motif) GRIP PF01465.20 EEB08673.1 - 3.8e-10 39.5 0.1 8.9e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 GRIP domain YabA PF06156.13 EEB08673.1 - 0.013 16.1 4.5 0.013 16.1 4.5 2.6 1 1 2 3 3 3 0 Initiation control protein YabA HALZ PF02183.18 EEB08673.1 - 0.014 15.6 4.5 0.027 14.7 3.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper HalX PF08663.10 EEB08673.1 - 0.069 13.5 10.8 0.37 11.1 9.0 2.6 1 1 1 2 2 2 0 HalX domain SlyX PF04102.12 EEB08673.1 - 0.31 11.7 7.9 3.1 8.5 3.3 2.7 1 1 1 2 2 2 0 SlyX ERM PF00769.19 EEB08673.1 - 0.74 9.6 26.8 1.2 8.9 24.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NRBF2 PF08961.10 EEB08673.1 - 8.4 5.9 16.5 11 5.5 14.2 2.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Actin PF00022.19 EEB08674.1 - 7.1e-69 232.4 0.0 1.9e-35 122.2 0.0 2.8 2 1 0 3 3 3 2 Actin MreB_Mbl PF06723.13 EEB08674.1 - 0.047 12.5 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein GBR_NSP5 PF17580.2 EEB08674.1 - 0.22 11.3 4.0 0.59 9.9 1.1 2.3 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 Kin17_mid PF10357.9 EEB08675.1 - 3e-53 179.0 3.3 4.5e-53 178.5 3.3 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EEB08675.1 - 0.00016 22.0 4.0 0.00035 20.9 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEB08675.1 - 0.0015 18.7 2.5 0.0034 17.6 2.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding HCV_NS5a_1b PF08301.13 EEB08675.1 - 0.015 15.8 0.0 7 7.3 0.0 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b Ribosomal_S10 PF00338.22 EEB08675.1 - 0.065 13.5 1.0 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e zf-C2H2_2 PF12756.7 EEB08675.1 - 0.51 10.7 9.8 0.19 12.1 2.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 EEB08675.1 - 1.1 9.5 7.0 0.36 11.1 2.9 2.1 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DER1 PF04511.15 EEB08676.1 - 6.6e-37 127.3 10.4 8e-37 127.0 10.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF2070 PF09843.9 EEB08676.1 - 2.9 6.1 10.3 3.2 5.9 10.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMF_TATA_bd PF12325.8 EEB08677.1 - 3.8e-29 101.2 59.2 2.6e-27 95.3 17.0 4.8 3 2 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EEB08677.1 - 4.8e-16 58.5 7.6 4.8e-16 58.5 7.6 6.6 3 3 3 6 6 6 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EEB08677.1 - 0.00018 21.8 54.7 0.0087 16.3 17.3 3.7 2 2 1 3 3 3 2 Autophagy protein 16 (ATG16) FPP PF05911.11 EEB08677.1 - 0.0024 16.1 4.5 0.0024 16.1 4.5 3.9 2 1 1 3 3 3 2 Filament-like plant protein, long coiled-coil HOOK PF05622.12 EEB08677.1 - 0.016 13.4 48.1 0.23 9.6 12.1 2.3 2 0 0 2 2 2 0 HOOK protein Fez1 PF06818.15 EEB08677.1 - 0.031 14.7 44.7 0.97 9.9 5.6 3.4 2 1 1 3 3 3 0 Fez1 Spc7 PF08317.11 EEB08677.1 - 0.054 12.4 54.4 0.12 11.2 14.1 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EEB08677.1 - 0.091 12.1 33.2 0.25 10.6 5.3 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EEB08677.1 - 0.16 11.7 52.6 1.4 8.8 1.7 6.9 4 2 1 6 6 6 0 Septum formation initiator GAS PF13851.6 EEB08677.1 - 0.43 9.9 56.5 1.5 8.1 7.7 4.0 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EEB08677.1 - 0.45 10.0 46.1 2.1 7.8 9.9 3.3 2 1 1 3 3 3 0 Intermediate filament protein CALCOCO1 PF07888.11 EEB08677.1 - 0.52 9.1 48.7 0.046 12.6 9.9 3.0 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.7 EEB08677.1 - 0.75 9.9 62.9 2 8.5 6.1 4.2 2 1 1 3 3 3 0 Tropomyosin like AAA_13 PF13166.6 EEB08677.1 - 0.81 8.2 40.4 0.056 12.1 5.4 2.9 1 1 2 3 3 3 0 AAA domain MAD PF05557.13 EEB08677.1 - 2.4 6.4 54.8 0.25 9.7 18.0 3.1 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF3890 PF13029.6 EEB08677.1 - 2.7 8.5 7.5 0.75 10.3 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) HMMR_N PF15905.5 EEB08677.1 - 8.9 5.7 60.4 0.19 11.2 13.3 3.3 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Rad60-SLD PF11976.8 EEB08678.1 - 8.9e-23 79.9 0.1 1.1e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEB08678.1 - 4.6e-12 45.5 0.1 5.5e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Hist_deacetyl PF00850.19 EEB08679.1 - 1.6e-83 280.7 0.0 2.2e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EEB08679.1 - 1.1e-75 254.1 0.1 2e-75 253.3 0.0 1.5 2 0 0 2 2 2 1 Arb2 domain Whi5 PF08528.11 EEB08680.1 - 7e-11 41.5 0.3 1.8e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Whi5 like RIBIOP_C PF04950.12 EEB08681.1 - 4.1e-96 321.9 0.3 4.1e-96 321.9 0.3 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEB08681.1 - 7.2e-32 109.3 0.0 2.2e-31 107.8 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EEB08681.1 - 6.3e-06 25.9 0.0 0.0036 16.9 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEB08681.1 - 6.5e-05 23.0 0.1 0.00028 21.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EEB08681.1 - 7.1e-05 23.1 0.3 0.00035 20.8 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EEB08681.1 - 0.00029 21.3 0.0 0.00084 19.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EEB08681.1 - 0.00037 20.3 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EEB08681.1 - 0.00054 20.5 0.0 0.0025 18.3 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EEB08681.1 - 0.0021 18.5 0.0 0.0021 18.5 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 EEB08681.1 - 0.0021 18.2 1.5 0.0083 16.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EEB08681.1 - 0.012 16.2 0.0 0.012 16.2 0.0 3.8 4 1 0 4 4 3 0 AAA domain AAA_30 PF13604.6 EEB08681.1 - 0.032 13.9 1.3 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEB08681.1 - 0.036 14.5 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 EEB08681.1 - 0.038 14.2 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EEB08681.1 - 0.062 12.5 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 EEB08681.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EEB08681.1 - 0.1 13.0 0.2 0.1 13.0 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEB08681.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EEB08681.1 - 0.11 12.3 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EEB08681.1 - 0.12 12.2 0.4 0.37 10.7 0.4 1.8 1 0 0 1 1 1 0 NTPase cobW PF02492.19 EEB08681.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EEB08681.1 - 0.16 11.7 0.1 0.39 10.4 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EEB08681.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EEB08681.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.6 3 1 0 3 3 2 0 AAA domain GLE1 PF07817.13 EEB08682.1 - 3.8e-67 226.1 1.9 3.8e-67 226.1 1.9 1.8 2 0 0 2 2 2 1 GLE1-like protein DDHD PF02862.17 EEB08682.1 - 1.7 8.7 10.8 3 7.9 10.8 1.5 1 0 0 1 1 1 0 DDHD domain MAJIN PF15077.6 EEB08682.1 - 2.3 8.0 16.2 3.9 7.2 16.2 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Borrelia_P83 PF05262.11 EEB08682.1 - 3.4 6.1 37.8 9.5 4.6 36.7 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein CDC45 PF02724.14 EEB08682.1 - 6.2 5.0 23.1 8.3 4.6 23.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.11 EEB08682.1 - 6.4 6.8 27.2 9.4 6.2 27.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SNARE PF05739.19 EEB08683.1 - 1.6e-13 50.4 0.9 1.6e-13 50.4 0.9 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EEB08683.1 - 1.5e-07 31.7 3.3 1.5e-07 31.7 3.3 3.3 1 1 2 3 3 3 1 Syntaxin-like protein Syntaxin PF00804.25 EEB08683.1 - 6.9e-05 22.6 9.6 6.9e-05 22.6 9.6 1.6 2 0 0 2 2 2 1 Syntaxin T2SSF PF00482.23 EEB08683.1 - 0.0044 17.0 4.6 0.036 14.0 0.1 2.8 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F TMPIT PF07851.13 EEB08683.1 - 0.063 12.5 4.4 0.076 12.2 3.0 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF4988 PF16378.5 EEB08683.1 - 0.068 12.8 1.6 0.13 11.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF5345 PF17280.2 EEB08683.1 - 0.087 12.8 2.3 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Herpes_US9 PF06072.11 EEB08683.1 - 0.16 11.9 0.9 0.3 11.0 0.9 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Transposase_22 PF02994.14 EEB08683.1 - 0.18 12.0 4.3 4.3 7.6 0.2 3.2 1 1 1 3 3 3 0 L1 transposable element RBD-like domain Acyl-CoA_dh_2 PF08028.11 EEB08683.1 - 0.38 11.0 5.3 0.3 11.3 2.0 2.3 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1664 PF07889.12 EEB08683.1 - 6.1 6.9 7.8 3.4 7.7 0.7 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) MCU PF04678.13 EEB08683.1 - 8.2 6.5 7.1 76 3.3 7.1 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter ubiquitin PF00240.23 EEB08684.1 - 1.3e-06 28.0 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EEB08684.1 - 0.00026 21.4 0.0 0.0023 18.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EEB08684.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E1-E2_ATPase PF00122.20 EEB08685.1 - 1.5e-52 177.7 0.5 1.5e-52 177.7 0.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEB08685.1 - 8.7e-49 165.7 3.0 8.7e-49 165.7 3.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEB08685.1 - 9.9e-17 61.9 0.3 3.4e-13 50.4 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB08685.1 - 1.5e-15 57.0 0.0 3.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEB08685.1 - 1.2e-14 53.8 0.0 3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEB08685.1 - 1.9e-06 27.8 0.8 8.9e-05 22.4 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 EEB08685.1 - 0.0026 17.9 5.4 0.7 10.1 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3784) DUF2127 PF09900.9 EEB08685.1 - 0.039 14.2 0.3 0.15 12.3 0.3 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) RseC_MucC PF04246.12 EEB08685.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC OppC_N PF12911.7 EEB08685.1 - 3.2 7.8 6.0 0.82 9.7 0.3 2.9 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ATG_C PF09333.11 EEB08686.1 - 5e-24 84.5 0.0 1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EEB08686.1 - 6.2e-16 58.5 0.1 2.4e-15 56.7 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EEB08686.1 - 4e-14 52.6 0.1 1.5e-13 50.7 0.1 2.1 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 EEB08686.1 - 0.0013 18.5 0.2 0.007 16.2 0.1 2.4 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Bac_rhamnosid_C PF17390.2 EEB08686.1 - 0.026 14.3 0.0 2.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase C-terminal domain 6PGD PF00393.19 EEB08687.2 - 3.7e-125 417.1 0.0 4.5e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EEB08687.2 - 3.2e-49 167.1 0.0 4.8e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ub-Mut7C PF14451.6 EEB08687.2 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin NAD_binding_11 PF14833.6 EEB08687.2 - 0.17 12.1 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 EEB08688.2 - 1.8e-35 120.6 0.1 1.3e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB08688.2 - 1.1e-14 54.3 0.1 1.8e-06 28.0 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEB08688.2 - 1e-05 25.4 0.0 0.067 13.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EEB08688.2 - 0.14 12.2 1.0 3.9 7.6 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Senescence_reg PF04520.13 EEB08688.2 - 0.48 11.3 9.0 0.58 11.0 7.7 1.7 2 0 0 2 2 2 0 Senescence regulator Presenilin PF01080.17 EEB08688.2 - 2.7 6.7 3.9 3.6 6.2 3.9 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EEB08689.1 - 1.3e-42 146.0 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08689.1 - 7e-26 91.1 0.0 1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EEB08689.1 - 0.033 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 EEB08689.1 - 0.15 11.4 0.1 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Rep_fac-A_C PF08646.10 EEB08690.1 - 8.1e-55 184.6 3.9 2.5e-53 179.8 0.7 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EEB08690.1 - 3.8e-35 119.7 1.6 3.1e-34 116.8 0.5 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EEB08690.1 - 3.4e-29 100.9 0.3 3.2e-28 97.7 0.1 2.3 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EEB08690.1 - 1.8e-15 56.7 0.9 6.2e-13 48.5 0.1 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 EEB08690.1 - 1.7e-05 25.1 1.1 6.8e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 EEB08690.1 - 0.00039 20.2 0.5 0.17 11.6 0.0 2.6 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 EEB08690.1 - 0.00098 17.1 0.2 0.011 13.6 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5521) DUF4539 PF15072.6 EEB08690.1 - 0.0034 17.4 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) IBR PF01485.21 EEB08690.1 - 0.011 15.9 1.2 0.024 14.9 1.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EEB08690.1 - 0.16 12.2 1.8 0.29 11.3 1.8 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 EEB08690.1 - 0.18 11.8 1.3 0.42 10.6 1.3 1.5 1 0 0 1 1 1 0 zinc-ribbons Aminotran_5 PF00266.19 EEB08691.1 - 8.9e-24 84.1 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEB08691.1 - 2.7e-06 26.2 0.0 3.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEB08691.1 - 5.4e-05 22.5 0.0 8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 EEB08691.1 - 0.026 13.1 0.0 0.075 11.6 0.0 1.7 2 0 0 2 2 2 0 Serine hydroxymethyltransferase PDCD2_C PF04194.13 EEB08692.2 - 3.7e-34 118.3 2.3 3.7e-34 118.3 2.3 1.5 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain ANAPC4_WD40 PF12894.7 EEB08693.1 - 1.2e-12 48.0 0.4 0.00067 19.9 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB08693.1 - 6e-12 45.9 6.3 0.007 17.2 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 EEB08693.1 - 0.003 17.5 0.0 0.078 12.8 0.2 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ribosomal_S6e PF01092.19 EEB08694.1 - 4.7e-59 197.8 0.6 1.6e-58 196.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e CFAP91 PF14738.6 EEB08694.1 - 0.03 14.4 5.5 0.041 14.0 5.5 1.2 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 HECT PF00632.25 EEB08695.1 - 3.5e-89 299.3 6.2 7.5e-89 298.2 0.1 3.4 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 EEB08695.1 - 9.8e-44 149.8 11.2 1e-42 146.5 2.1 3.5 2 1 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EEB08695.1 - 1.7e-39 136.2 4.4 1.7e-39 136.2 4.4 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBM PF14377.6 EEB08695.1 - 5.1e-07 28.9 1.9 0.028 13.9 0.4 2.8 2 0 0 2 2 2 2 Ubiquitin binding region GDC-P PF02347.16 EEB08696.1 - 6.9e-199 661.1 0.3 7.4e-185 614.9 0.0 3.0 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EEB08696.1 - 3.1e-08 33.0 0.1 1.8e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEB08696.1 - 0.0001 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF760 PF05542.11 EEB08696.1 - 0.074 13.4 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Frataxin_Cyay PF01491.16 EEB08697.1 - 5.5e-38 129.4 0.1 6.9e-38 129.0 0.1 1.1 1 0 0 1 1 1 1 Frataxin-like domain GST_N PF02798.20 EEB08698.2 - 1.3e-11 44.7 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EEB08698.2 - 1.1e-09 38.3 0.2 2.6e-09 37.2 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEB08698.2 - 1.2e-05 25.3 0.4 3.4e-05 23.8 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEB08698.2 - 1.3e-05 25.3 0.1 2.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_97 PF10566.9 EEB08698.2 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Sec15 PF04091.12 EEB08699.2 - 1.8e-74 251.0 2.2 1.8e-74 251.0 2.2 2.1 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 EEB08699.2 - 2.5e-07 30.7 3.9 2.5e-07 30.7 3.9 2.6 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain Cytidylate_kin PF02224.18 EEB08699.2 - 0.11 12.2 0.4 0.29 10.9 0.4 1.6 1 0 0 1 1 1 0 Cytidylate kinase COG5 PF10392.9 EEB08699.2 - 0.14 12.3 4.9 0.61 10.3 1.9 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4200 PF13863.6 EEB08699.2 - 0.14 12.5 9.0 0.034 14.5 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DASH_Dad2 PF08654.10 EEB08699.2 - 0.34 11.3 3.6 2.4 8.7 2.3 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Prefoldin_2 PF01920.20 EEB08699.2 - 0.63 10.0 7.6 0.046 13.7 1.8 2.1 2 0 0 2 2 2 0 Prefoldin subunit COG2 PF06148.11 EEB08699.2 - 6.3 6.9 8.8 4.6 7.3 2.8 3.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF410 PF04190.13 EEB08700.1 - 1.7e-71 241.0 0.6 2e-71 240.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF4992 PF16383.5 EEB08700.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function P5-ATPase PF12409.8 EEB08701.1 - 9.3e-36 122.7 0.7 3.5e-35 120.8 0.6 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EEB08701.1 - 1.7e-30 105.9 1.1 4.5e-29 101.2 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEB08701.1 - 1.9e-12 47.9 0.3 3.4e-05 24.2 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB08701.1 - 5.9e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEB08701.1 - 7.8e-06 25.5 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Abhydrolase_9_N PF15420.6 EEB08701.1 - 0.33 10.9 2.6 0.36 10.8 0.2 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus CAF1C_H4-bd PF12265.8 EEB08702.2 - 1.1e-26 92.9 1.2 8.5e-26 90.0 0.2 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEB08702.2 - 3.7e-24 84.5 10.8 1.6e-05 25.6 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08702.2 - 6.3e-06 26.4 1.4 0.13 12.6 0.0 3.7 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TatD_DNase PF01026.21 EEB08703.2 - 1.2e-37 129.7 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SET PF00856.28 EEB08704.1 - 7.3e-12 46.0 0.1 1.4e-11 45.1 0.1 1.5 1 0 0 1 1 1 1 SET domain Glyco_transf_34 PF05637.12 EEB08705.1 - 1.4e-77 260.6 0.1 1.7e-77 260.4 0.1 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family KH_8 PF17903.1 EEB08706.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EEB08706.1 - 0.28 11.0 1.0 0.51 10.2 0.4 1.7 2 0 0 2 2 2 0 KH domain DUF1640 PF07798.11 EEB08707.1 - 5.6e-46 156.8 5.5 6.4e-46 156.6 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 EEB08707.1 - 0.21 11.8 4.8 0.71 10.1 0.6 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Phage_GPO PF05929.11 EEB08707.1 - 0.71 9.4 5.6 0.24 11.0 1.8 1.7 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PRP1_N PF06424.12 EEB08707.1 - 4.5 7.6 6.9 14 6.0 1.4 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal RNB PF00773.19 EEB08710.1 - 5.3e-99 331.6 0.0 1.2e-98 330.5 0.0 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EEB08710.1 - 2.2e-19 69.2 0.0 7.5e-19 67.5 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EEB08710.1 - 0.00022 21.5 0.0 0.00066 20.0 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 EEB08710.1 - 0.0082 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Methyltr_RsmB-F PF01189.17 EEB08711.1 - 8e-31 107.2 0.0 1.2e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EEB08711.1 - 0.0042 16.9 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08711.1 - 0.0059 17.3 0.0 0.024 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EEB08711.1 - 0.078 12.4 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 EEB08711.1 - 0.15 12.7 0.0 3.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_22 PF03901.17 EEB08712.1 - 1.6e-59 202.2 31.4 2.1e-59 201.9 31.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-C2H2 PF00096.26 EEB08713.1 - 4.2e-13 49.0 14.8 4.4e-06 26.8 0.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEB08713.1 - 4.8e-11 42.6 13.3 2e-06 28.0 1.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEB08713.1 - 1.9e-07 31.3 12.4 0.076 13.9 0.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 EEB08713.1 - 0.00067 20.0 10.2 0.33 11.4 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEB08713.1 - 0.0017 18.3 8.6 1.7 8.7 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEB08713.1 - 0.0044 17.3 9.9 0.86 10.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 EEB08713.1 - 0.043 14.1 6.1 0.3 11.3 5.8 2.3 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 EEB08713.1 - 0.34 10.7 6.0 3.6 7.4 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EEB08713.1 - 2.9 8.4 5.1 20 5.7 0.2 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PfkB PF00294.24 EEB08714.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PNP_UDP_1 PF01048.20 EEB08715.1 - 1.8e-38 132.1 0.0 2.2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4777 PF16007.5 EEB08715.1 - 0.0096 16.2 0.2 0.11 12.8 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4777) NMD3 PF04981.13 EEB08716.2 - 1.1e-66 224.8 7.7 3e-63 213.5 3.9 2.1 1 1 1 2 2 2 2 NMD3 family GcpE PF04551.14 EEB08716.2 - 0.027 13.6 0.2 0.039 13.1 0.2 1.2 1 0 0 1 1 1 0 GcpE protein DZR PF12773.7 EEB08716.2 - 5.1 7.2 11.6 5.7 7.0 6.0 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 EEB08717.1 - 1.8e-21 75.6 12.2 1.8e-21 75.6 12.2 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EEB08717.1 - 1.4e-06 28.1 0.0 3.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 EEB08717.1 - 0.0018 18.1 8.2 0.32 10.9 9.1 2.6 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EEB08717.1 - 0.0018 18.3 3.7 0.0018 18.3 3.7 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger Rtf2 PF04641.12 EEB08717.1 - 0.01 15.2 2.2 0.019 14.4 2.2 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Baculo_IE-1 PF05290.11 EEB08717.1 - 0.014 15.3 4.1 0.03 14.3 4.1 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 EEB08717.1 - 0.028 14.7 12.0 0.028 14.7 12.0 1.9 2 0 0 2 2 2 0 Ring finger domain COX6C PF02937.15 EEB08717.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc zf-C3HC4_2 PF13923.6 EEB08717.1 - 2.1 8.3 16.0 0.2 11.6 11.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EEB08718.1 - 1.9e-12 46.8 6.7 1.9e-12 46.8 6.7 2.5 2 0 0 2 2 2 1 PHD-finger FYVE_2 PF02318.16 EEB08718.1 - 2.9 8.1 7.9 0.49 10.6 0.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.22 EEB08718.1 - 3.3 7.7 24.0 0.58 10.1 2.3 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fic_N PF13784.6 EEB08719.1 - 0.12 12.4 2.9 0.15 12.1 1.3 1.9 2 0 0 2 2 2 0 Fic/DOC family N-terminal UPF1_Zn_bind PF09416.10 EEB08720.1 - 3.5e-70 234.9 3.0 8.7e-70 233.6 3.0 1.7 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EEB08720.1 - 2.4e-59 200.3 0.0 5.3e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEB08720.1 - 2.9e-52 178.1 2.8 6.4e-28 98.3 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EEB08720.1 - 4.7e-31 106.9 0.0 9.8e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EEB08720.1 - 1.9e-16 60.4 0.1 8.3e-16 58.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB08720.1 - 1e-11 45.4 0.0 2.2e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EEB08720.1 - 1.2e-06 28.6 0.0 3e-06 27.3 0.0 1.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EEB08720.1 - 4.4e-05 23.1 0.1 0.0015 18.1 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EEB08720.1 - 0.00012 21.5 5.6 0.00054 19.3 0.1 3.5 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EEB08720.1 - 0.0017 18.2 0.1 0.0043 16.9 0.1 1.7 1 1 0 1 1 1 1 Helicase DEAD PF00270.29 EEB08720.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 EEB08720.1 - 0.026 14.9 0.4 0.061 13.7 0.1 1.8 2 0 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 EEB08720.1 - 0.038 14.3 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EEB08720.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Transp_Tc5_C PF04236.15 EEB08720.1 - 0.046 14.1 1.4 0.12 12.7 1.4 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain PhoH PF02562.16 EEB08720.1 - 0.056 12.9 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 EEB08720.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EEB08720.1 - 0.088 13.2 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EEB08720.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEB08720.1 - 0.13 11.6 0.0 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 KaiC PIF1 PF05970.14 EEB08720.1 - 0.18 11.0 0.1 13 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Pkinase PF00069.25 EEB08721.2 - 1.3e-53 182.0 0.0 2.2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08721.2 - 5.1e-24 84.9 0.0 1.3e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEB08721.2 - 0.00012 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Urb2 PF10441.9 EEB08722.1 - 1.3e-30 106.9 1.0 1.3e-30 106.9 1.0 3.8 3 2 0 3 3 3 1 Urb2/Npa2 family Fels1 PF05666.11 EEB08722.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Sec1 PF00995.23 EEB08723.1 - 1.4e-121 407.5 6.3 1.6e-121 407.4 6.3 1.0 1 0 0 1 1 1 1 Sec1 family YxiJ PF14176.6 EEB08723.1 - 0.046 14.2 0.7 2.5 8.6 0.1 2.9 2 1 1 3 3 3 0 YxiJ-like protein G-patch PF01585.23 EEB08724.1 - 1.8e-08 34.1 0.2 3.2e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 G-patch domain BRO1 PF03097.18 EEB08725.1 - 3.7e-65 220.2 10.4 8.4e-65 219.1 10.4 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEB08725.1 - 6e-20 71.7 20.6 6e-20 71.7 20.6 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV RPW8 PF05659.11 EEB08725.1 - 1 9.0 6.1 0.36 10.5 0.1 3.2 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Syntaxin_2 PF14523.6 EEB08725.1 - 1.7 9.1 23.9 0.95 9.9 0.3 5.0 3 2 2 5 5 5 0 Syntaxin-like protein AAA PF00004.29 EEB08726.1 - 4e-44 150.2 0.0 7.7e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEB08726.1 - 2.7e-27 94.5 0.0 8.3e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EEB08726.1 - 7.2e-23 80.4 6.5 1.4e-22 79.5 6.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EEB08726.1 - 1.2e-10 41.1 0.0 4.4e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EEB08726.1 - 3.5e-06 27.5 0.2 3.4e-05 24.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EEB08726.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEB08726.1 - 3.4e-05 23.8 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEB08726.1 - 8e-05 22.9 0.7 0.004 17.4 0.3 2.6 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EEB08726.1 - 8.6e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EEB08726.1 - 0.00015 21.8 0.1 0.0008 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EEB08726.1 - 0.00033 20.8 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EEB08726.1 - 0.00058 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EEB08726.1 - 0.00069 19.8 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEB08726.1 - 0.0007 19.2 0.4 0.13 11.8 0.1 2.6 2 1 0 3 3 2 1 AAA domain TIP49 PF06068.13 EEB08726.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EEB08726.1 - 0.0014 19.2 0.0 0.005 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEB08726.1 - 0.002 17.9 0.0 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EEB08726.1 - 0.0039 17.6 0.1 0.015 15.7 0.0 2.1 3 0 0 3 3 1 1 RNA helicase AAA_17 PF13207.6 EEB08726.1 - 0.0046 17.4 0.0 0.013 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 EEB08726.1 - 0.0081 15.5 0.1 1.8 7.9 0.0 2.4 1 1 1 2 2 2 1 KaiC Mg_chelatase PF01078.21 EEB08726.1 - 0.028 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EEB08726.1 - 0.038 13.9 0.1 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ParB PF08775.10 EEB08726.1 - 0.054 14.0 0.1 0.45 11.0 0.0 2.3 2 0 0 2 2 2 0 ParB family Zeta_toxin PF06414.12 EEB08726.1 - 0.067 12.5 0.1 3.3 6.9 0.1 2.3 1 1 1 2 2 2 0 Zeta toxin PPV_E1_C PF00519.17 EEB08726.1 - 0.18 10.6 1.4 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase PhoH PF02562.16 EEB08726.1 - 0.41 10.1 1.8 0.45 9.9 0.1 1.9 3 0 0 3 3 3 0 PhoH-like protein PP2C PF00481.21 EEB08727.1 - 5.4e-85 285.1 0.0 7.5e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CUB PF00431.20 EEB08727.1 - 0.02 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 CUB domain SMN PF06003.12 EEB08728.1 - 2.4e-05 23.7 10.7 0.00013 21.4 7.6 2.4 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Trypan_PARP PF05887.11 EEB08728.1 - 1.8 8.6 10.5 2.4 8.1 10.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RSN1_7TM PF02714.15 EEB08729.2 - 9.3e-82 274.4 23.8 9.3e-82 274.4 23.8 2.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EEB08729.2 - 4.4e-38 131.3 0.0 6.7e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EEB08729.2 - 4.4e-30 104.5 5.8 4.4e-30 104.5 5.8 3.3 4 2 0 4 4 4 1 Late exocytosis, associated with Golgi transport SYCP2_SLD PF18584.1 EEB08729.2 - 0.025 14.8 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain ThiF PF00899.21 EEB08730.1 - 5.7e-60 202.7 0.0 8.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EEB08730.1 - 3.2e-07 30.8 0.0 1.4e-05 25.5 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EEB08730.1 - 0.0019 18.3 0.1 0.062 13.4 0.0 2.4 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EEB08730.1 - 0.075 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HA2 PF04408.23 EEB08731.1 - 3.8e-22 78.6 0.4 7.3e-22 77.7 0.0 1.7 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEB08731.1 - 9.5e-16 57.9 0.1 2.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEB08731.1 - 1e-14 54.8 0.0 5.7e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB08731.1 - 2.7e-07 30.5 0.0 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB08731.1 - 0.00012 22.3 0.0 0.00062 20.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EEB08731.1 - 0.0092 16.0 0.1 0.27 11.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEB08731.1 - 0.017 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEB08731.1 - 0.018 15.5 0.0 0.14 12.7 0.0 2.3 1 1 1 2 2 2 0 ABC transporter AAA_30 PF13604.6 EEB08731.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEB08731.1 - 0.026 14.0 0.0 0.22 11.0 0.0 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EEB08731.1 - 0.032 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.6 EEB08731.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EEB08731.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EEB08731.1 - 0.056 12.5 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EEB08731.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Helicase_RecD PF05127.14 EEB08731.1 - 0.097 12.5 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_33 PF13671.6 EEB08731.1 - 0.13 12.4 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EEB08732.1 - 1e-21 77.5 0.0 8e-21 74.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 EEB08732.1 - 2.5e-19 69.1 0.2 1e-18 67.2 0.1 2.1 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 EEB08732.1 - 4.4e-18 65.6 0.0 4.9e-15 55.8 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EEB08732.1 - 1.5e-16 60.9 6.5 4.3e-16 59.4 6.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EEB08732.1 - 1.4e-14 53.9 0.0 3.3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 EEB08732.1 - 1.1e-05 25.5 0.0 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATG22 PF11700.8 EEB08733.1 - 2e-91 307.0 22.0 2.4e-91 306.8 22.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EEB08733.1 - 0.00027 20.0 43.8 0.0016 17.5 1.1 3.8 2 1 2 4 4 4 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EEB08733.1 - 0.0026 16.7 23.3 0.0035 16.2 0.2 2.3 1 1 1 2 2 2 1 MFS_1 like family Wzy_C PF04932.15 EEB08733.1 - 0.0054 16.4 0.3 0.0054 16.4 0.3 3.4 2 1 0 2 2 2 1 O-Antigen ligase DUF3591 PF12157.8 EEB08734.2 - 8.6e-181 601.4 1.1 1.6e-180 600.5 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EEB08734.2 - 1.4e-05 24.8 1.5 3.7e-05 23.5 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EEB08734.2 - 0.0027 17.7 1.0 0.0052 16.8 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle LprI PF07007.12 EEB08734.2 - 0.024 15.3 0.3 0.092 13.4 0.3 2.0 1 0 0 1 1 1 0 Lysozyme inhibitor LprI TFIIF_beta PF02270.15 EEB08734.2 - 0.12 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Methyltransf_15 PF09445.10 EEB08735.1 - 8.9e-44 149.0 0.0 1.2e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EEB08735.1 - 8.7e-05 23.2 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08735.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EEB08735.1 - 0.00056 19.7 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EEB08735.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_Mtase PF02384.16 EEB08735.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Gp_dh_C PF02800.20 EEB08736.1 - 9.1e-72 239.8 0.1 1.3e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEB08736.1 - 4e-40 136.2 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EEB08736.1 - 0.028 14.5 1.6 0.1 12.7 0.4 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EEB08736.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3576 PF12100.8 EEB08736.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) FKBP_C PF00254.28 EEB08737.1 - 1.8e-29 101.9 0.1 5.4e-29 100.4 0.1 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EEB08737.1 - 1.2e-19 70.7 0.0 1.2e-19 70.7 0.0 2.4 2 1 0 2 2 1 1 Nucleoplasmin-like domain SDA1 PF05285.12 EEB08737.1 - 0.00013 21.5 20.1 0.0002 20.9 20.1 1.4 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.12 EEB08737.1 - 0.0023 16.6 31.3 0.0023 16.6 31.3 1.4 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EEB08737.1 - 0.0094 14.2 22.1 0.012 13.9 22.1 1.1 1 0 0 1 1 1 1 Nop14-like family HGTP_anticodon2 PF12745.7 EEB08737.1 - 0.26 10.8 15.2 0.027 14.0 10.8 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs RR_TM4-6 PF06459.12 EEB08737.1 - 1.8 8.3 27.1 3.4 7.4 27.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EEB08737.1 - 3.2 6.0 20.6 5.2 5.2 20.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EEB08737.1 - 4.8 5.9 9.1 6.1 5.5 9.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EEB08737.1 - 4.8 5.8 10.0 7.4 5.2 10.0 1.4 1 0 0 1 1 1 0 Presenilin Peptidase_S30 PF01577.16 EEB08737.1 - 6.1 6.4 8.4 9.4 5.8 8.4 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease CCSAP PF15748.5 EEB08737.1 - 8.5 6.5 19.2 14 5.8 19.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated IMS PF00817.20 EEB08738.1 - 1.8e-40 138.4 0.0 4.8e-40 137.0 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 EEB08738.1 - 4.9e-16 58.9 0.1 1.2e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EEB08738.1 - 5e-11 43.3 0.1 7.4e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EEB08738.1 - 3.9e-10 40.0 0.0 1e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EEB08738.1 - 5.6e-05 23.5 0.0 0.00021 21.6 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 EEB08738.1 - 0.0005 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EEB08738.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 IMS family HHH motif UBM PF14377.6 EEB08738.1 - 3.2 7.3 5.1 23 4.6 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin binding region WD40 PF00400.32 EEB08739.1 - 4.9e-18 65.2 20.5 0.00022 21.9 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08739.1 - 4.5e-09 36.5 3.0 0.00051 20.3 0.1 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB08739.1 - 0.045 12.7 1.7 4.1 6.3 0.1 3.6 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AMP-binding PF00501.28 EEB08740.1 - 1e-88 297.8 0.0 2.1e-88 296.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Rhomboid PF01694.22 EEB08741.1 - 3.1e-19 69.5 10.1 2.5e-18 66.5 10.1 2.1 1 1 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 EEB08741.1 - 0.44 10.9 4.3 2.1 8.7 1.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) zf-H2C2_2 PF13465.6 EEB08742.1 - 2.3e-06 27.8 13.1 6.4e-06 26.4 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EEB08742.1 - 1.3e-05 25.3 19.5 0.0014 19.0 1.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEB08742.1 - 0.00013 22.5 12.4 0.036 14.9 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EEB08742.1 - 0.0034 17.6 2.2 0.0083 16.4 0.8 2.3 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EEB08742.1 - 0.012 15.9 1.6 0.03 14.6 1.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEB08742.1 - 0.027 14.5 3.9 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 EEB08742.1 - 0.1 12.3 1.3 0.18 11.5 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) PTS_2-RNA PF01885.16 EEB08743.1 - 5.5e-63 212.3 0.0 7.7e-63 211.8 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Yae1_N PF09811.9 EEB08743.1 - 0.00022 20.9 2.1 0.0015 18.2 2.1 2.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SHMT PF00464.19 EEB08744.2 - 4.4e-205 680.8 0.0 5.2e-205 680.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EEB08744.2 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ras PF00071.22 EEB08745.1 - 1.8e-63 213.0 0.7 2.2e-63 212.7 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB08745.1 - 9.2e-35 119.5 0.2 1.6e-34 118.7 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB08745.1 - 1.8e-13 50.3 0.2 2.7e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EEB08745.1 - 2.2e-06 27.7 0.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEB08745.1 - 4.7e-06 26.7 0.1 7e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEB08745.1 - 0.00038 20.0 0.2 0.00085 18.9 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3533 PF12051.8 EEB08745.1 - 0.0021 17.1 0.2 0.0025 16.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Gtr1_RagA PF04670.12 EEB08745.1 - 0.0026 17.1 0.2 0.0041 16.5 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EEB08745.1 - 0.01 16.1 0.1 0.062 13.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EEB08745.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EEB08745.1 - 0.023 15.2 0.3 0.038 14.5 0.3 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 EEB08745.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 EEB08745.1 - 0.05 13.4 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB08745.1 - 0.052 13.3 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EEB08745.1 - 0.074 13.1 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EEB08745.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 EEB08745.1 - 0.13 11.8 0.2 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Peptidase_C93 PF06035.11 EEB08745.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Chromo PF00385.24 EEB08746.1 - 2.2e-13 49.9 2.6 5.6e-13 48.6 2.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.22 EEB08746.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB08746.1 - 0.028 14.4 0.0 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Fungal_trans PF04082.18 EEB08747.1 - 2e-24 86.1 0.0 3.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB08747.1 - 2.2e-09 37.3 13.1 2.2e-09 37.3 13.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L15e PF00827.17 EEB08748.1 - 6e-88 293.6 8.4 7.3e-88 293.3 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Sdh_cyt PF01127.22 EEB08749.1 - 4.8e-25 88.0 4.0 6.8e-25 87.5 4.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sin_N PF04801.13 EEB08750.1 - 6.4e-32 111.3 0.0 7.7e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Ribosomal_L24e PF01246.20 EEB08751.1 - 3.9e-30 103.9 0.1 3.9e-30 103.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e ISG65-75 PF11727.8 EEB08751.1 - 0.23 10.6 10.1 0.27 10.4 10.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein SEN1_N PF12726.7 EEB08752.1 - 7.1e-112 375.0 30.4 6.9e-63 213.0 13.3 2.4 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.6 EEB08752.1 - 2e-75 254.0 0.5 2e-75 254.0 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EEB08752.1 - 6.8e-60 202.1 0.0 1.8e-59 200.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEB08752.1 - 1.1e-08 35.0 0.2 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEB08752.1 - 1.3e-07 32.1 0.1 3e-06 27.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEB08752.1 - 4.7e-05 23.2 0.3 0.67 9.6 0.0 4.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EEB08752.1 - 0.056 12.9 9.7 0.5 9.8 0.1 3.3 3 1 1 4 4 4 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 EEB08752.1 - 0.17 12.3 0.3 2.1 8.8 0.4 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4570 PF15134.6 EEB08752.1 - 1.3 9.1 5.7 5.8 7.0 5.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4407 PF14362.6 EEB08752.1 - 2.1 7.6 4.3 4.2 6.6 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ccdc124 PF06244.12 EEB08753.1 - 7.8e-27 94.4 27.0 4.9e-26 91.8 27.0 2.0 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Mt_ATP-synt_D PF05873.12 EEB08754.1 - 1.4e-13 50.9 4.7 1.8e-13 50.6 4.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Tmemb_cc2 PF10267.9 EEB08754.1 - 0.0015 17.7 0.9 0.0017 17.5 0.9 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ATPase PF06745.13 EEB08754.1 - 0.073 12.4 0.6 0.094 12.1 0.6 1.2 1 0 0 1 1 1 0 KaiC DUF2408 PF10303.9 EEB08754.1 - 0.1 13.1 1.4 0.21 12.2 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) AcetDehyd-dimer PF09290.11 EEB08754.1 - 0.12 12.5 0.4 3.9 7.7 0.1 2.4 1 1 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation CT_C_D PF02682.16 EEB08754.1 - 0.18 11.5 0.3 0.23 11.2 0.3 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Rad21_Rec8_N PF04825.13 EEB08755.1 - 4.5e-27 94.4 0.2 1.1e-26 93.2 0.2 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EEB08755.1 - 4.7e-08 32.2 0.7 1.1e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein AAA PF00004.29 EEB08756.1 - 1.4e-17 64.4 0.0 4.6e-17 62.7 0.0 1.9 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EEB08756.1 - 1.9e-10 40.8 0.4 5.4e-10 39.3 0.4 1.7 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 EEB08756.1 - 9.4e-09 35.2 0.1 4.1e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.6 EEB08756.1 - 2.7e-08 34.4 0.0 3.4e-07 30.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEB08756.1 - 6.8e-08 32.9 0.0 2.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEB08756.1 - 7.7e-05 23.1 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEB08756.1 - 0.00013 21.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EEB08756.1 - 0.0012 18.8 0.0 0.0064 16.4 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EEB08756.1 - 0.0031 17.4 0.0 0.013 15.4 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 EEB08756.1 - 0.042 13.6 0.0 0.042 13.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 EEB08756.1 - 0.055 12.7 0.1 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 EEB08756.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PIF1 PF05970.14 EEB08756.1 - 0.16 11.1 0.1 0.49 9.5 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase Cyt-b5 PF00173.28 EEB08758.2 - 4.7e-23 81.1 0.1 6.1e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3951 PF13131.6 EEB08758.2 - 0.015 15.5 0.3 0.024 14.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF1682 PF07946.14 EEB08759.1 - 1e-82 277.9 0.2 1.2e-82 277.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SPG4 PF17325.2 EEB08759.1 - 0.19 12.9 1.9 0.4 11.8 1.9 1.6 1 0 0 1 1 1 0 Stationary phase protein 4 V-ATPase_G PF03179.15 EEB08759.1 - 0.21 12.1 8.0 0.45 11.1 8.0 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mt_ATP-synt_B PF05405.14 EEB08759.1 - 2.1 8.0 5.6 14 5.3 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CK_II_beta PF01214.18 EEB08760.2 - 2e-73 246.1 0.0 2.4e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p62 PF05502.13 EEB08760.2 - 0.31 9.8 0.8 0.47 9.2 0.8 1.2 1 0 0 1 1 1 0 Dynactin p62 family ATP_bind_3 PF01171.20 EEB08761.1 - 3e-19 69.5 0.0 5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EEB08761.1 - 4e-15 55.0 2.4 4e-15 55.0 2.4 3.8 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 EEB08761.1 - 0.0057 16.2 0.7 0.0057 16.2 0.7 3.5 4 0 0 4 4 4 1 RecR protein HIPIP PF01355.17 EEB08761.1 - 0.89 9.9 3.4 9.5 6.7 0.1 3.3 3 0 0 3 3 3 0 High potential iron-sulfur protein DZR PF12773.7 EEB08761.1 - 1.7 8.7 12.4 2.5 8.2 1.1 3.2 3 0 0 3 3 3 0 Double zinc ribbon DUF2616 PF11077.8 EEB08761.1 - 4 7.1 7.7 0.52 10.0 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) COPIIcoated_ERV PF07970.12 EEB08762.1 - 3.3e-31 108.9 0.0 6.1e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEB08762.1 - 8.2e-24 83.8 1.3 8.2e-24 83.8 1.3 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3139 PF11337.8 EEB08762.1 - 0.14 12.9 0.5 0.32 11.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Transketolase_N PF00456.21 EEB08763.1 - 9.3e-147 488.3 0.0 1.2e-146 487.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EEB08763.1 - 1.6e-48 164.8 0.0 5e-48 163.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEB08763.1 - 1.6e-14 53.8 0.0 3.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EEB08763.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EEB08763.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Acyltransferase PF01553.21 EEB08764.1 - 5.5e-27 94.0 0.0 1.2e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EEB08764.1 - 3.4e-15 55.9 0.1 9e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Mob1_phocein PF03637.17 EEB08765.1 - 5.8e-75 251.0 1.1 6.8e-75 250.7 1.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pept_S41_N PF18294.1 EEB08765.1 - 0.51 10.4 3.1 1.3 9.1 0.4 2.5 3 0 0 3 3 3 0 Peptidase S41 N-terminal domain RRM_1 PF00076.22 EEB08766.1 - 6.2e-19 67.6 0.0 8.3e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB08766.1 - 0.00011 22.3 0.1 0.001 19.1 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif UCR_14kD PF02271.16 EEB08766.1 - 0.0014 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Nup35_RRM_2 PF14605.6 EEB08766.1 - 0.0016 18.4 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 EEB08766.1 - 0.0022 17.9 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 RL domain RRM_5 PF13893.6 EEB08766.1 - 0.0097 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB08766.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EEB08766.1 - 0.027 14.5 0.1 0.088 12.9 0.1 1.8 1 1 0 1 1 1 0 Limkain b1 RNA_bind PF08675.11 EEB08766.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain SbcD_C PF12320.8 EEB08766.1 - 0.067 13.5 0.1 0.084 13.2 0.1 1.1 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain RRM_8 PF11835.8 EEB08766.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Sec5 PF15469.6 EEB08767.2 - 4.4e-30 104.9 0.6 4.4e-30 104.9 0.6 2.2 3 0 0 3 3 3 1 Exocyst complex component Sec5 GCN5L1 PF06320.13 EEB08767.2 - 0.048 13.8 1.9 0.11 12.7 0.8 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) RRM_1 PF00076.22 EEB08768.1 - 8.5e-08 31.9 0.0 7.6e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB08768.1 - 1.5e-05 24.9 0.0 0.0063 16.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EEB08768.1 - 0.00025 21.0 2.2 0.00045 20.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger domain Spc7 PF08317.11 EEB08768.1 - 0.00041 19.3 4.5 0.0048 15.8 4.2 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein RRM_occluded PF16842.5 EEB08768.1 - 0.0023 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 EEB08768.1 - 0.0078 16.1 3.7 0.013 15.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PHM7_cyt PF14703.6 EEB08768.1 - 0.01 16.0 0.5 0.74 10.0 0.0 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-C4H2 PF10146.9 EEB08768.1 - 0.019 15.3 1.3 0.019 15.3 1.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4523 PF15023.6 EEB08768.1 - 0.024 14.5 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) FAM76 PF16046.5 EEB08768.1 - 0.027 13.8 1.9 0.043 13.2 1.9 1.2 1 0 0 1 1 1 0 FAM76 protein Bul1_C PF04426.12 EEB08768.1 - 0.035 13.5 1.2 0.061 12.7 1.2 1.3 1 0 0 1 1 1 0 Bul1 C terminus RRM_3 PF08777.11 EEB08768.1 - 0.04 14.0 2.2 0.078 13.0 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1330 PF07045.11 EEB08768.1 - 0.062 13.6 0.1 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) zf-CCCH_2 PF14608.6 EEB08768.1 - 0.095 13.2 1.9 0.19 12.2 1.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger YlzJ PF14035.6 EEB08768.1 - 0.14 12.3 0.2 13 6.1 0.1 2.7 2 0 0 2 2 2 0 YlzJ-like protein NAM-associated PF14303.6 EEB08768.1 - 6.8 7.4 11.3 0.17 12.6 4.5 1.8 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain Spo7 PF03907.13 EEB08769.1 - 6.9e-36 123.8 10.5 2.3e-30 105.7 8.1 2.1 1 1 1 2 2 2 2 Spo7-like protein Histone PF00125.24 EEB08770.1 - 1.7e-20 73.7 0.4 2.3e-20 73.3 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEB08770.1 - 2e-06 28.0 0.1 3.9e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EEB08770.1 - 7.4e-05 23.2 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EEB08770.1 - 0.021 14.9 0.1 0.024 14.7 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein DUF3915 PF13054.6 EEB08770.1 - 0.056 13.4 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Xpo1 PF08389.12 EEB08770.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Exportin 1-like protein Histone_H2A_C PF16211.5 EEB08771.1 - 1.9e-18 65.9 1.2 3.5e-18 65.0 1.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EEB08771.1 - 1.6e-16 60.8 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEB08771.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HIT PF01230.23 EEB08771.1 - 0.09 13.5 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 HIT domain FA_desaturase PF00487.24 EEB08772.1 - 1.2e-19 71.1 17.5 1.2e-19 71.1 17.5 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEB08772.1 - 4.8e-11 42.7 0.0 8.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CRC_subunit PF08624.10 EEB08773.1 - 2e-51 173.9 0.0 3.8e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 EEB08774.2 - 1e-11 44.6 8.2 1.7e-11 43.8 8.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-RRPl_C4 PF17026.5 EEB08774.2 - 0.0019 18.3 1.8 0.0035 17.4 1.8 1.4 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 EEB08774.2 - 0.0075 16.2 4.4 0.015 15.2 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 EEB08774.2 - 0.01 15.4 3.9 0.01 15.4 3.9 1.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EEB08774.2 - 0.017 15.0 1.1 0.017 15.0 1.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 EEB08774.2 - 0.22 11.5 4.9 0.11 12.5 2.0 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.12 EEB08774.2 - 0.27 11.2 4.3 0.52 10.3 4.3 1.4 1 0 0 1 1 1 0 zinc-ribbons PHD_2 PF13831.6 EEB08774.2 - 0.75 9.4 10.5 0.14 11.7 5.4 2.4 2 1 0 2 2 2 0 PHD-finger C1_2 PF03107.16 EEB08774.2 - 0.95 9.8 5.6 0.69 10.3 1.1 2.4 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 EEB08774.2 - 3.8 7.4 7.6 10 6.0 7.6 1.7 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon NOB1_Zn_bind PF08772.11 EEB08774.2 - 5.7 7.2 7.9 6.5 7.0 3.7 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like NAD_kinase PF01513.21 EEB08775.1 - 2.4e-55 187.8 0.0 3.5e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EEB08775.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPALS PF18178.1 EEB08775.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Thioredoxin_11 PF18078.1 EEB08776.1 - 0.045 13.9 1.7 0.53 10.4 0.4 2.9 2 1 0 2 2 2 0 Thioredoxin-like SNTX domain DUF1366 PF07104.11 EEB08776.1 - 0.075 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Proteasome PF00227.26 EEB08777.1 - 1.1e-56 191.4 0.1 1.4e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB08777.1 - 7.6e-14 51.1 0.0 1.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.27 EEB08778.2 - 7.5e-36 123.7 0.0 1.8e-17 64.1 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EEB08778.2 - 4.9e-16 59.4 2.9 8.9e-06 25.7 0.0 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEB08778.2 - 3.6e-05 23.4 0.0 0.048 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EEB08778.2 - 0.00014 21.4 0.4 1 8.7 0.1 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEB08778.2 - 0.00026 21.6 0.0 0.66 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EEB08778.2 - 0.00042 20.5 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EEB08778.2 - 0.0031 17.5 0.2 0.4 10.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 EEB08778.2 - 0.014 15.4 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EEB08778.2 - 0.015 15.5 0.0 0.27 11.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEB08778.2 - 0.043 13.2 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EEB08778.2 - 0.051 13.2 0.2 4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase1 PF18748.1 EEB08778.2 - 0.065 12.7 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Pox_A32 PF04665.12 EEB08778.2 - 0.1 12.0 0.1 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.6 EEB08778.2 - 0.12 12.7 1.6 13 6.0 0.1 3.5 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEB08778.2 - 0.17 12.3 0.0 5.7 7.3 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain MTS PF05175.14 EEB08779.1 - 3.2e-05 23.6 0.0 0.00024 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EEB08779.1 - 0.036 13.7 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 ThiF PF00899.21 EEB08780.1 - 3.4e-22 79.0 0.0 5e-21 75.2 0.0 2.2 1 1 0 1 1 1 1 ThiF family DUF5087 PF17006.5 EEB08780.1 - 0.072 12.6 4.0 0.98 8.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5087) MatE PF01554.18 EEB08781.1 - 7e-54 181.8 35.8 1.4e-34 119.0 9.5 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EEB08781.1 - 0.0089 16.1 38.3 0.013 15.5 13.7 3.6 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF4477 PF14780.6 EEB08782.1 - 6.2e-07 29.2 0.9 0.0007 19.3 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) SR-25 PF10500.9 EEB08782.1 - 0.012 15.2 9.4 0.017 14.8 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.6 EEB08782.1 - 0.76 10.2 5.8 0.24 11.8 1.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gly_transf_sug PF04488.15 EEB08783.1 - 2.7e-18 66.4 0.2 8.1e-18 64.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EEB08783.1 - 0.0054 16.2 0.2 0.0068 15.8 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein LSM PF01423.22 EEB08784.1 - 2.1e-20 72.2 0.1 2.3e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEB08784.1 - 3.1e-06 27.2 0.0 3.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EEB08784.1 - 0.0066 16.5 0.0 0.0072 16.4 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain TPR_1 PF00515.28 EEB08785.1 - 1.7e-08 33.9 6.4 0.0037 17.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEB08785.1 - 2.2e-06 27.4 9.1 0.31 11.2 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEB08785.1 - 0.00034 20.9 4.0 0.036 14.4 1.7 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB08785.1 - 0.021 15.3 5.2 0.021 15.3 2.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEB08785.1 - 0.5 10.3 3.5 1.6 8.7 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB08785.1 - 0.87 10.6 5.7 1.9 9.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_I_A49 PF06870.12 EEB08786.1 - 2.1e-104 349.4 1.1 2.5e-104 349.2 1.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SSB PF00436.25 EEB08787.1 - 1.4e-10 41.1 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Aldo_ket_red PF00248.21 EEB08788.1 - 5.4e-46 157.1 0.0 1.2e-35 123.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Myb_DNA-bind_6 PF13921.6 EEB08788.1 - 0.14 12.4 0.3 3.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain HEAT_EZ PF13513.6 EEB08789.1 - 4.4e-28 97.3 3.8 5.6e-14 52.3 0.0 9.7 10 1 1 11 11 10 4 HEAT-like repeat HEAT PF02985.22 EEB08789.1 - 1.8e-21 74.4 9.5 0.0061 16.7 0.0 9.7 10 0 0 10 10 9 6 HEAT repeat HEAT_2 PF13646.6 EEB08789.1 - 2.3e-13 50.3 0.1 0.001 19.4 0.0 6.7 6 2 3 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EEB08789.1 - 2.8e-07 31.0 0.0 1.1 9.9 0.0 5.0 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EEB08789.1 - 3e-07 30.6 0.0 0.026 14.5 0.0 4.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EEB08789.1 - 2.4e-06 27.4 4.5 1.8 8.7 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EEB08789.1 - 4.7e-06 25.4 0.2 0.013 14.1 0.0 3.2 2 1 0 2 2 2 2 Adaptin N terminal region IBN_N PF03810.19 EEB08789.1 - 1.8e-05 24.6 0.1 0.00011 22.1 0.1 2.5 1 1 1 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EEB08789.1 - 0.00057 19.8 0.0 4.8 7.1 0.0 5.1 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EEB08789.1 - 0.0017 18.0 0.0 22 4.5 0.0 4.7 4 1 0 4 4 4 0 CLASP N terminal RTP1_C1 PF10363.9 EEB08789.1 - 0.0017 18.5 0.1 0.0094 16.1 0.0 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EEB08789.1 - 0.0029 17.6 0.1 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central MMS19_C PF12460.8 EEB08789.1 - 0.019 14.1 3.8 0.49 9.5 0.0 3.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 EEB08789.1 - 0.035 14.2 0.1 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Cnd3 PF12719.7 EEB08789.1 - 0.05 12.8 0.1 8.5 5.5 0.0 3.1 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain FA_FANCE PF11510.8 EEB08789.1 - 0.072 12.4 0.6 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Fanconi Anaemia group E protein FANCE TAFH PF07531.14 EEB08789.1 - 1 9.5 7.4 5.2 7.2 0.1 4.5 5 1 1 6 6 6 0 NHR1 homology to TAF MFS_2 PF13347.6 EEB08790.1 - 6.3e-12 44.8 14.0 6.3e-12 44.8 14.0 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 EEB08790.1 - 2.9e-06 25.8 2.9 5.4e-06 24.9 2.9 1.4 1 0 0 1 1 1 1 BT1 family MFS_1_like PF12832.7 EEB08790.1 - 6.9e-05 21.9 6.9 9.6e-05 21.4 6.1 1.6 1 1 1 2 2 2 1 MFS_1 like family Reticulon PF02453.17 EEB08790.1 - 0.0037 17.3 3.3 0.0037 17.3 3.3 2.8 3 0 0 3 3 3 1 Reticulon Aminotran_1_2 PF00155.21 EEB08791.1 - 1.4e-70 238.3 0.0 2e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 EEB08791.1 - 0.00013 22.4 0.5 0.00056 20.4 0.1 2.3 3 0 0 3 3 3 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.20 EEB08791.1 - 0.00019 20.1 0.0 0.00035 19.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EEB08791.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Vps54 PF07928.12 EEB08793.1 - 3.9e-29 101.8 0.3 1.6e-28 99.8 0.1 2.3 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EEB08793.1 - 0.00071 18.9 0.4 0.2 10.9 0.1 3.3 2 1 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex DUF2063 PF09836.9 EEB08793.1 - 0.037 14.3 0.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain tRNA_bind_2 PF13725.6 EEB08793.1 - 0.077 12.7 1.6 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Possible tRNA binding domain DHR10 PF18595.1 EEB08793.1 - 0.099 12.7 0.8 0.23 11.5 0.8 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DHHA2 PF02833.14 EEB08794.1 - 7.2e-27 94.3 0.3 1.3e-26 93.5 0.3 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EEB08794.1 - 1.9e-11 44.1 0.1 7.6e-11 42.2 0.0 1.9 1 1 1 2 2 2 1 DHH family PAS_12 PF18095.1 EEB08794.1 - 0.075 12.7 0.6 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain WW PF00397.26 EEB08797.1 - 4.5e-06 26.6 2.1 1.4e-05 25.1 2.1 1.8 1 0 0 1 1 1 1 WW domain Pkinase PF00069.25 EEB08798.2 - 6.8e-81 271.5 0.0 8.5e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08798.2 - 4.2e-34 118.0 0.0 5.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08798.2 - 0.0019 17.5 0.1 0.012 14.9 0.0 2.1 1 1 2 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EEB08798.2 - 0.023 13.7 0.0 0.41 9.5 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EEB08798.2 - 0.024 13.4 0.5 0.037 12.8 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase zinc_ribbon_6 PF14599.6 EEB08799.1 - 1.4e-23 82.7 4.2 1.4e-23 82.7 4.2 4.1 3 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EEB08799.1 - 2.3e-16 60.1 29.7 2.3e-16 60.1 29.7 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EEB08799.1 - 1e-07 32.2 8.3 1e-07 32.2 8.3 5.5 2 1 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEB08799.1 - 0.00022 21.0 7.9 0.00022 21.0 7.9 5.7 5 3 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) DUF1542 PF07564.11 EEB08799.1 - 0.022 14.8 0.5 0.022 14.8 0.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) SKG6 PF08693.10 EEB08800.1 - 0.00055 19.3 5.0 0.00055 19.3 5.0 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Rax2 PF12768.7 EEB08800.1 - 0.0026 17.2 0.1 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity LapA_dom PF06305.11 EEB08800.1 - 0.2 11.5 0.1 0.44 10.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HECT PF00632.25 EEB08801.1 - 1e-102 343.8 0.1 1.5e-102 343.3 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EEB08801.1 - 1.1e-35 121.4 19.5 1.5e-12 47.4 5.0 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EEB08801.1 - 3.5e-20 72.2 0.1 1.2e-19 70.5 0.1 2.0 1 0 0 1 1 1 1 C2 domain BNIP3 PF06553.12 EEB08801.1 - 0.049 13.3 1.6 0.084 12.5 1.6 1.3 1 0 0 1 1 1 0 BNIP3 ubiquitin PF00240.23 EEB08802.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EEB08802.1 - 7e-32 109.1 12.1 1.1e-31 108.5 12.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EEB08802.1 - 1.9e-16 59.6 0.7 3e-16 59.0 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEB08802.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EEB08802.1 - 0.0034 17.7 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EEB08802.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEB08802.1 - 0.0065 16.6 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EEB08802.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EEB08802.1 - 0.026 15.1 0.1 0.03 14.9 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EEB08802.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Acyl_transf_1 PF00698.21 EEB08803.1 - 1.9e-17 63.8 0.0 4.9e-16 59.1 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain DUF1864 PF08933.11 EEB08803.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Ecl1 PF12855.7 EEB08804.1 - 0.00038 21.7 9.1 0.00041 21.6 9.1 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Thg1 PF04446.12 EEB08804.1 - 0.045 13.8 0.1 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 tRNAHis guanylyltransferase CF222 PF15661.5 EEB08805.1 - 0.23 10.3 0.1 0.25 10.2 0.1 1.0 1 0 0 1 1 1 0 C6orf222, uncharacterised family ZZ PF00569.17 EEB08806.2 - 2.6e-14 52.7 40.8 1.4e-06 28.0 7.0 3.8 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 EEB08806.2 - 3e-09 37.5 0.0 5.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 EEB08806.2 - 1.3e-07 31.8 40.9 0.00014 22.1 8.4 3.8 4 0 0 4 4 4 3 C1 domain NUDIX PF00293.28 EEB08807.1 - 5.6e-14 52.3 1.2 2.1e-13 50.5 0.1 2.1 1 1 1 2 2 2 2 NUDIX domain Med15_fungi PF05397.12 EEB08810.2 - 2e-29 102.1 0.1 2e-29 102.1 0.1 5.7 5 2 1 6 6 6 1 Mediator complex subunit 15 KIX_2 PF16987.5 EEB08810.2 - 3.7e-13 49.3 3.1 3.7e-13 49.3 3.1 3.1 3 1 0 3 3 3 1 KIX domain Gal11_ABD1 PF18535.1 EEB08810.2 - 1.3e-11 44.4 9.9 1.3e-11 44.4 9.9 5.2 3 2 1 4 4 4 1 Gal11 activator-binding domain (ABD1) SNF2_N PF00176.23 EEB08811.1 - 4.2e-55 186.9 0.3 9e-55 185.8 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_7 PF18586.1 EEB08811.1 - 4e-41 139.3 0.1 6.5e-40 135.4 0.1 3.2 3 0 0 3 3 3 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Helicase_C PF00271.31 EEB08811.1 - 3.6e-20 72.4 0.1 1.8e-18 66.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCCH_6 PF18585.1 EEB08811.1 - 3.5e-17 62.0 0.2 1.7e-16 59.9 0.1 2.4 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 HDA2-3 PF11496.8 EEB08811.1 - 2e-12 46.9 4.1 6.8e-12 45.1 4.1 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EEB08811.1 - 7e-05 22.9 0.2 0.0048 16.9 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PHD PF00628.29 EEB08811.1 - 0.00012 21.9 9.3 0.00012 21.9 9.3 2.8 2 0 0 2 2 2 1 PHD-finger Chromo PF00385.24 EEB08811.1 - 0.0013 18.6 1.6 0.13 12.2 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ERCC3_RAD25_C PF16203.5 EEB08811.1 - 0.0034 16.7 0.3 0.0071 15.6 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RVT_N PF13655.6 EEB08811.1 - 9.1 6.6 6.3 18 5.7 0.3 3.2 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase zf-U1 PF06220.12 EEB08812.1 - 1.9e-12 46.7 0.5 5e-12 45.4 0.5 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-CCHC PF00098.23 EEB08813.1 - 1.6e-12 46.9 31.5 0.00012 22.0 5.6 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 EEB08813.1 - 0.067 12.9 34.2 0.19 11.5 1.5 5.2 3 1 2 5 5 5 0 Zinc knuckle TPP_enzyme_N PF02776.18 EEB08814.1 - 2.1e-56 190.2 0.3 7.1e-56 188.5 0.1 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEB08814.1 - 2.3e-49 167.1 0.1 3.1e-48 163.4 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEB08814.1 - 4.3e-42 143.1 0.0 1e-41 141.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain OAM_dimer PF16554.5 EEB08814.1 - 0.16 12.4 0.1 9.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase Nucleoporin_C PF03177.14 EEB08815.1 - 3.7e-19 68.9 13.7 6.1e-19 68.2 13.4 1.5 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EEB08815.1 - 1.1e-18 67.3 1.9 2.2e-18 66.3 1.9 1.5 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 EEB08816.1 - 5.4e-26 91.5 0.0 7.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08816.1 - 1.3e-10 41.0 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB08816.1 - 7.7e-07 28.2 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB08816.1 - 0.0011 18.9 0.0 0.026 14.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Shugoshin_N PF07558.11 EEB08817.1 - 5.9e-07 29.3 1.4 2e-06 27.5 1.4 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Leu_zip PF15294.6 EEB08817.1 - 0.0018 17.8 4.4 0.0029 17.2 4.4 1.3 1 0 0 1 1 1 1 Leucine zipper NAD_binding_4 PF07993.12 EEB08817.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Shugoshin_C PF07557.11 EEB08817.1 - 0.024 14.4 8.3 0.024 14.4 8.3 3.7 4 0 0 4 4 4 0 Shugoshin C terminus ZapB PF06005.12 EEB08817.1 - 0.028 14.9 1.5 0.028 14.9 1.5 2.6 2 1 1 3 3 2 0 Cell division protein ZapB GldM_N PF12081.8 EEB08817.1 - 0.045 13.8 1.5 0.073 13.2 1.5 1.3 1 0 0 1 1 1 0 GldM N-terminal domain V_ATPase_I PF01496.19 EEB08817.1 - 0.11 10.5 1.3 0.15 10.0 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.13 EEB08817.1 - 0.13 12.2 2.5 0.24 11.3 2.5 1.4 1 0 0 1 1 1 0 Sec20 BRE1 PF08647.11 EEB08817.1 - 0.14 12.3 4.2 0.43 10.7 4.2 1.9 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 EEB08817.1 - 0.14 12.2 2.6 0.22 11.5 2.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GIT_CC PF16559.5 EEB08817.1 - 0.18 11.7 7.6 0.64 9.9 0.7 2.7 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 EEB08817.1 - 1.1 9.3 7.3 3.2 7.8 1.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc42p PF11544.8 EEB08817.1 - 4.3 7.4 7.6 2.9 8.0 0.2 3.2 2 1 0 2 2 2 0 Spindle pole body component Spc42p FlxA PF14282.6 EEB08817.1 - 9 6.4 9.3 1.2 9.2 5.0 1.8 2 0 0 2 2 2 0 FlxA-like protein PITH PF06201.13 EEB08818.1 - 9e-37 126.6 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain Evr1_Alr PF04777.13 EEB08820.1 - 4.2e-25 88.1 0.0 5.9e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 EEB08820.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.7 1 1 1 2 2 2 0 APOBEC1 CWC25 PF12542.8 EEB08821.1 - 5.5e-19 69.0 5.0 5.5e-19 69.0 5.0 3.5 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EEB08821.1 - 2.3e-15 56.5 12.9 2.3e-15 56.5 12.9 5.3 4 1 0 4 4 4 2 N-terminal domain of CBF1 interacting co-repressor CIR VRR_NUC PF08774.11 EEB08822.1 - 2e-24 85.8 0.0 4.8e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain RRM_1 PF00076.22 EEB08823.2 - 1.4e-24 85.6 0.1 6.1e-16 58.0 0.0 4.1 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB08823.2 - 0.031 14.4 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 EEB08823.2 - 0.072 13.0 0.0 5.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif eIF-1a PF01176.19 EEB08824.1 - 7.6e-19 67.3 0.0 1.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Amino_oxidase PF01593.24 EEB08825.2 - 1.6e-55 189.2 0.1 2.9e-55 188.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EEB08825.2 - 5.7e-12 45.8 0.0 1.6e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EEB08825.2 - 1.8e-06 28.1 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EEB08825.2 - 2.5e-06 27.8 0.6 8.9e-06 26.0 0.6 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box NAD_binding_9 PF13454.6 EEB08825.2 - 4.3e-06 26.8 0.1 0.038 14.0 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EEB08825.2 - 6.2e-05 22.4 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.10 EEB08825.2 - 0.0034 17.9 1.4 0.0084 16.7 0.6 2.1 1 1 1 2 2 2 1 HMG-box domain DAO PF01266.24 EEB08825.2 - 0.036 13.6 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fasciclin PF02469.22 EEB08826.1 - 9.5e-06 25.9 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain NgoMIV_restric PF09015.10 EEB08826.1 - 0.053 12.6 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme FAD_binding_3 PF01494.19 EEB08828.1 - 1.7e-22 80.2 0.0 3e-21 76.1 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EEB08828.1 - 1.7e-05 24.1 0.1 0.016 14.2 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.10 EEB08828.1 - 0.00034 19.7 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EEB08828.1 - 0.0012 18.2 0.0 0.0086 15.3 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB08828.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEB08828.1 - 0.0042 17.3 0.2 0.0084 16.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEB08828.1 - 0.014 15.0 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EEB08828.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EEB08828.1 - 0.019 14.1 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EEB08828.1 - 0.059 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEB08828.1 - 0.18 10.4 0.7 0.39 9.4 0.7 1.6 1 1 0 1 1 1 0 HI0933-like protein Myosin_head PF00063.21 EEB08829.1 - 2.5e-235 782.8 7.6 3.2e-235 782.5 7.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EEB08829.1 - 1.1e-46 158.9 1.4 1.9e-46 158.1 1.4 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EEB08829.1 - 3e-16 58.7 0.1 1.8e-15 56.3 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEB08829.1 - 7.4e-13 48.1 0.0 2.7e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEB08829.1 - 1.8e-09 37.1 0.0 9.1e-09 34.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SepF PF04472.12 EEB08829.1 - 0.0012 19.0 0.4 0.63 10.3 0.0 3.4 3 0 0 3 3 3 1 Cell division protein SepF SH3_3 PF08239.11 EEB08829.1 - 0.0028 17.9 0.7 0.014 15.7 0.0 2.5 4 0 0 4 4 4 1 Bacterial SH3 domain AAA_22 PF13401.6 EEB08829.1 - 0.012 15.8 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EEB08829.1 - 0.078 12.5 0.3 10 5.6 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EEB08829.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EEB08829.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IQ PF00612.27 EEB08829.1 - 9.4 6.3 8.7 5.8 7.0 3.8 2.5 1 1 1 2 2 2 0 IQ calmodulin-binding motif Adaptin_N PF01602.20 EEB08830.1 - 8.5e-90 301.8 13.1 1.3e-89 301.1 13.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EEB08830.1 - 2.6e-52 176.5 0.3 6e-52 175.3 0.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EEB08830.1 - 3.1e-52 175.9 0.3 1.1e-51 174.2 0.1 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EEB08830.1 - 7.3e-11 42.4 11.5 6.5e-07 29.5 0.1 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEB08830.1 - 1.6e-09 38.0 3.6 0.0002 21.7 0.0 4.8 5 1 1 6 6 5 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EEB08830.1 - 2.9e-05 24.2 0.1 0.00021 21.4 0.0 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EEB08830.1 - 3e-05 23.9 0.5 0.19 12.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 EEB08830.1 - 0.0011 18.9 1.1 4.7 7.4 0.1 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEB08830.1 - 0.0028 18.1 0.5 1.9 9.1 0.2 3.7 3 0 0 3 3 3 1 HEAT-like repeat ParcG PF10274.9 EEB08830.1 - 0.005 17.0 9.8 4.3 7.4 0.7 4.2 3 1 1 4 4 4 3 Parkin co-regulated protein HEAT_UF PF18817.1 EEB08830.1 - 0.057 13.7 3.0 2.9 8.2 0.0 4.3 5 0 0 5 5 5 0 Repeat of uncharacterized protein PH0542 Tubulin PF00091.25 EEB08831.1 - 6.2e-68 228.9 0.0 2.3e-67 227.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEB08831.1 - 2.5e-41 140.8 0.0 4.8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EEB08831.1 - 1.2e-05 25.5 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EEB08831.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EEB08831.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like GN3L_Grn1 PF08701.11 EEB08832.1 - 2e-25 88.7 13.9 5.9e-25 87.2 13.9 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EEB08832.1 - 1.8e-17 63.5 0.2 1e-12 48.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEB08832.1 - 6.4e-08 32.8 6.4 0.00038 20.6 0.1 3.7 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 EEB08832.1 - 2e-06 27.4 0.8 6.2e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EEB08832.1 - 3.6e-06 26.6 0.0 0.0027 17.3 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB08832.1 - 1.3e-05 25.1 0.6 0.00015 21.7 0.6 2.2 1 1 0 1 1 1 1 RsgA GTPase MeaB PF03308.16 EEB08832.1 - 0.023 13.7 0.7 0.18 10.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EEB08832.1 - 0.067 13.4 0.1 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EEB08832.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NOG1 PF06858.14 EEB08832.1 - 0.099 12.4 1.6 0.22 11.3 0.2 2.4 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 EEB08832.1 - 0.14 12.7 1.4 0.56 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 EEB08832.1 - 0.18 11.2 1.1 1.5 8.2 0.4 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF4820 PF16091.5 EEB08832.1 - 8.3 5.7 8.8 3.5 6.9 6.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CRC_subunit PF08624.10 EEB08833.1 - 7.3e-40 136.5 0.0 1.3e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Requiem_N PF14051.6 EEB08833.1 - 0.06 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Presenilin PF01080.17 EEB08833.1 - 0.062 12.1 5.3 0.075 11.8 5.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EEB08833.1 - 0.091 12.0 1.0 0.11 11.6 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EEB08833.1 - 0.16 10.2 9.4 0.19 10.0 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EEB08833.1 - 1.7 8.4 13.2 2.5 7.8 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 EEB08833.1 - 4.1 6.9 13.4 6.2 6.3 13.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 EEB08833.1 - 6.3 6.8 8.2 12 5.9 7.9 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RNB PF00773.19 EEB08834.1 - 4.5e-100 335.2 0.1 6.7e-100 334.6 0.1 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EEB08834.1 - 5.6e-25 87.1 1.1 1.3e-24 85.9 1.1 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EEB08834.1 - 5.7e-22 78.0 0.1 2.3e-21 76.1 0.1 2.0 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EEB08834.1 - 3.1e-20 72.0 0.0 9.5e-20 70.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EEB08834.1 - 1.1e-13 51.6 0.1 3.3e-13 50.1 0.1 1.9 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EEB08834.1 - 0.00011 22.3 0.0 0.0034 17.5 0.0 2.9 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 EEB08834.1 - 0.023 15.0 0.0 0.023 15.0 0.0 2.7 3 0 0 3 3 3 0 DIS3-like exonuclease 2 C terminal 4HBT PF03061.22 EEB08835.1 - 0.0015 18.9 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF359 PF04019.12 EEB08835.1 - 0.039 13.6 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) Cyto_heme_lyase PF01265.17 EEB08836.1 - 4.6e-55 187.3 8.7 5.6e-53 180.4 8.7 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase HMG_box PF00505.19 EEB08837.2 - 3.1e-13 49.9 0.2 5.1e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EEB08837.2 - 0.013 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 EEB08837.2 - 0.022 15.3 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Sec7 PF01369.20 EEB08838.1 - 4.7e-11 42.7 1.7 1.1e-10 41.5 1.7 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EEB08838.1 - 0.00083 19.7 0.0 0.0054 17.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain RPN7 PF10602.9 EEB08839.1 - 2.2e-37 128.4 2.6 5e-37 127.3 2.6 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EEB08839.1 - 2.3e-11 44.1 0.3 1.7e-10 41.3 0.1 2.5 2 0 0 2 2 2 1 PCI domain DUF2250 PF10007.9 EEB08839.1 - 5.8e-05 23.1 0.1 0.00049 20.2 0.2 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.19 EEB08839.1 - 0.1 12.5 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TPR_14 PF13428.6 EEB08839.1 - 0.11 13.4 0.5 1.4 9.9 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEB08839.1 - 0.32 11.2 6.9 1.8 8.9 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEB08839.1 - 0.81 9.6 5.1 4 7.4 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 EEB08839.1 - 0.93 8.4 5.9 0.12 11.3 0.7 2.1 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 Prefoldin PF02996.17 EEB08840.1 - 4.8e-26 91.0 1.0 7e-26 90.5 0.3 1.6 1 1 1 2 2 2 2 Prefoldin subunit DUF1192 PF06698.11 EEB08840.1 - 0.00053 20.0 0.8 0.0023 17.9 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 EEB08840.1 - 0.001 19.0 4.3 0.029 14.3 0.3 2.1 2 0 0 2 2 2 2 Prefoldin subunit V-SNARE PF05008.15 EEB08840.1 - 0.037 14.4 2.2 0.13 12.7 0.3 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus LURAP PF14854.6 EEB08840.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4795 PF16043.5 EEB08840.1 - 0.046 13.3 0.5 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) LPP PF04728.13 EEB08840.1 - 0.094 13.1 2.1 0.21 12.0 0.6 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper RabGAP-TBC PF00566.18 EEB08841.1 - 2.7e-52 177.5 1.3 6.2e-52 176.4 0.4 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 EEB08841.1 - 0.002 18.6 0.1 0.044 14.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EEB08841.1 - 0.0033 17.2 0.3 0.52 10.4 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EEB08841.1 - 0.013 15.0 0.1 0.32 10.7 0.0 3.0 2 0 0 2 2 2 0 EF hand CLAMP PF14769.6 EEB08841.1 - 0.063 13.7 0.9 2.6 8.6 0.6 2.6 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 GrpE PF01025.19 EEB08842.1 - 1.1e-49 168.3 1.8 1.3e-49 168.0 1.8 1.0 1 0 0 1 1 1 1 GrpE DUF641 PF04859.12 EEB08842.1 - 0.02 15.2 0.1 0.02 15.2 0.1 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3584 PF12128.8 EEB08842.1 - 0.024 12.2 3.9 0.029 11.9 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF924 PF06041.11 EEB08842.1 - 0.033 14.3 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) FAM184 PF15665.5 EEB08842.1 - 0.046 13.5 6.3 0.058 13.2 6.3 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B She9_MDM33 PF05546.11 EEB08842.1 - 0.068 13.0 4.1 0.094 12.5 4.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF4795 PF16043.5 EEB08842.1 - 0.071 12.7 4.4 0.1 12.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) PKcGMP_CC PF16808.5 EEB08842.1 - 0.092 12.6 0.7 0.092 12.6 0.7 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_S49 PF01343.18 EEB08842.1 - 0.094 12.7 0.4 0.14 12.1 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 GvpL_GvpF PF06386.11 EEB08842.1 - 0.096 12.6 3.6 0.13 12.2 3.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SLX9 PF15341.6 EEB08842.1 - 0.45 10.9 5.7 0.6 10.5 5.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4446 PF14584.6 EEB08842.1 - 0.47 10.4 4.4 1.9 8.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) PhoU PF01895.19 EEB08842.1 - 0.68 10.4 4.5 0.82 10.2 3.1 1.8 1 1 1 2 2 2 0 PhoU domain SlyX PF04102.12 EEB08842.1 - 3.2 8.4 5.4 11 6.8 5.4 1.9 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 EEB08842.1 - 4.7 7.0 8.4 3.9 7.3 6.7 1.6 1 1 0 1 1 1 0 Septum formation initiator ATP-synt_F PF01990.17 EEB08843.1 - 3.1e-30 104.3 0.3 3.6e-30 104.1 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Fe-S_biosyn PF01521.20 EEB08844.2 - 9.3e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Nup160 PF11715.8 EEB08845.1 - 8.1e-45 153.5 0.0 1.2e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Sterol-sensing PF12349.8 EEB08846.1 - 1.7e-28 99.4 6.7 4.1e-28 98.1 6.7 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.32 EEB08846.1 - 0.034 15.0 0.0 0.28 12.1 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat dsrm PF00035.26 EEB08847.1 - 2.2e-12 47.5 0.0 5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EEB08847.1 - 6.3e-06 26.4 0.0 2.1e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease-III-like DND1_DSRM PF14709.7 EEB08847.1 - 0.053 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_60s PF00428.19 EEB08848.1 - 2e-27 95.6 13.0 2.5e-27 95.3 13.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sybindin PF04099.12 EEB08849.1 - 1.1e-45 155.1 0.6 1.2e-45 155.0 0.6 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EEB08849.1 - 7.1e-08 32.6 0.7 2.1e-07 31.1 0.3 1.7 1 1 1 2 2 2 1 Sedlin, N-terminal conserved region RRM_1 PF00076.22 EEB08850.1 - 1.6e-21 75.9 0.0 2.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EEB08850.1 - 4.3e-21 75.1 1.3 4.3e-21 75.1 1.3 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 EEB08850.1 - 2.7e-12 46.1 5.3 2.7e-12 46.1 5.3 2.4 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EEB08850.1 - 0.014 15.4 0.1 0.061 13.4 0.0 2.1 2 1 0 3 3 3 0 RNA recognition motif DASH_Dad4 PF08650.10 EEB08851.1 - 1.1e-30 105.4 7.4 1.2e-30 105.2 7.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 EEB08851.1 - 0.0097 16.1 3.0 0.014 15.6 3.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Pecanex_C PF05041.15 EEB08851.1 - 0.028 14.0 0.2 0.03 13.9 0.2 1.1 1 0 0 1 1 1 0 Pecanex protein (C-terminus) V-SNARE_C PF12352.8 EEB08852.1 - 2.5e-17 62.9 4.6 5.1e-17 61.9 3.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EEB08852.1 - 3.7e-16 59.3 0.9 3.7e-16 59.3 0.9 1.9 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus eIF3m_C_helix PF18005.1 EEB08852.1 - 0.013 15.2 0.2 0.026 14.2 0.2 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix ZnuA PF01297.17 EEB08852.1 - 0.018 14.5 1.2 0.038 13.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Vps54_N PF10475.9 EEB08852.1 - 0.078 12.2 0.9 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 EEB08852.1 - 0.38 10.3 6.0 0.54 9.8 6.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YqjK PF13997.6 EEB08852.1 - 0.52 10.6 0.1 0.52 10.6 0.1 3.2 4 0 0 4 4 4 0 YqjK-like protein Prominin PF05478.11 EEB08852.1 - 0.58 8.0 4.0 5.2 4.9 4.0 1.9 1 1 0 1 1 1 0 Prominin DUF4972 PF16342.5 EEB08852.1 - 0.75 9.5 4.7 17 5.1 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4972) Vps36_ESCRT-II PF11605.8 EEB08853.1 - 7.9e-19 67.6 0.1 2e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 EEB08853.1 - 2.1e-18 66.5 0.8 4.1e-18 65.5 0.8 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family PH_TFIIH PF08567.11 EEB08853.1 - 0.00058 20.1 0.0 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain GRAM PF02893.20 EEB08853.1 - 0.0034 17.3 0.0 0.0094 15.8 0.0 1.7 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.18 EEB08853.1 - 0.0094 15.2 0.5 0.0094 15.2 0.5 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 EEB08853.1 - 0.022 14.2 1.7 0.022 14.2 1.7 3.4 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Flavodoxin_NdrI PF07972.11 EEB08853.1 - 0.065 13.4 0.8 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like DZR PF12773.7 EEB08853.1 - 0.35 10.9 7.2 9.2 6.4 7.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon PHD_4 PF16866.5 EEB08853.1 - 0.48 10.5 5.9 0.97 9.6 2.2 2.9 3 0 0 3 3 3 0 PHD-finger YokU PF14122.6 EEB08853.1 - 0.63 10.1 2.7 3.1 7.8 0.0 2.9 2 1 0 2 2 2 0 YokU-like protein, putative antitoxin Mago_nashi PF02792.14 EEB08854.2 - 2.1e-70 235.4 0.3 2.4e-70 235.2 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Complex1_49kDa PF00346.19 EEB08854.2 - 0.075 12.1 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit adh_short PF00106.25 EEB08856.1 - 1.7e-47 161.5 0.5 2.2e-47 161.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB08856.1 - 5.5e-30 104.6 0.4 6.8e-30 104.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB08856.1 - 3.8e-11 43.2 0.1 5.5e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEB08856.1 - 0.022 13.9 0.3 0.034 13.3 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GARS_N PF02844.15 EEB08856.1 - 0.058 14.2 0.2 1.6 9.6 0.0 2.6 2 1 1 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain Na_Ca_ex PF01699.24 EEB08857.1 - 7e-24 84.5 28.2 1.8e-15 57.2 12.3 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EEB08857.1 - 2.4e-09 37.8 10.1 2.4e-09 37.8 10.1 4.5 4 0 0 4 4 4 2 Inner membrane component domain DUF4131 PF13567.6 EEB08857.1 - 0.00061 19.5 0.0 0.00061 19.5 0.0 3.3 5 1 0 5 5 5 1 Domain of unknown function (DUF4131) Ribosomal_S8e PF01201.22 EEB08858.1 - 7.3e-57 191.4 0.7 8.3e-57 191.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e RNA_pol_Rpb2_6 PF00562.28 EEB08859.1 - 1.1e-126 423.0 0.2 1.8e-126 422.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEB08859.1 - 9.2e-77 257.1 0.1 1.3e-76 256.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEB08859.1 - 3.7e-53 180.0 0.2 8.8e-53 178.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EEB08859.1 - 1.6e-31 108.5 0.0 4.2e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EEB08859.1 - 4.6e-25 87.6 0.1 1.3e-24 86.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EEB08859.1 - 9.5e-25 86.7 1.0 1.8e-24 85.8 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EEB08859.1 - 5e-23 81.4 1.3 8.6e-23 80.7 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_45 PF10385.9 EEB08859.1 - 0.081 13.2 0.2 2 8.7 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain AMP-binding PF00501.28 EEB08860.1 - 1.5e-145 485.0 0.0 2.3e-72 243.9 0.0 4.5 4 1 1 5 5 5 4 AMP-binding enzyme Condensation PF00668.20 EEB08860.1 - 1.1e-140 469.3 27.8 1.4e-27 96.5 3.4 7.3 6 2 1 7 7 7 6 Condensation domain PP-binding PF00550.25 EEB08860.1 - 5.5e-36 122.7 10.2 1.7e-10 41.1 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EEB08860.1 - 2.8e-06 28.2 0.0 0.035 15.1 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Feld-I_B PF09252.10 EEB08860.1 - 0.067 13.2 0.2 18 5.4 0.1 2.9 2 0 0 2 2 2 0 Allergen Fel d I-B chain K_oxygenase PF13434.6 EEB08861.1 - 5.4e-110 367.7 0.0 6.6e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EEB08861.1 - 1.3e-07 31.2 0.0 5.6e-06 25.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB08861.1 - 7.3e-06 26.0 0.0 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EEB08861.1 - 3.4e-05 23.2 0.0 6.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase A_amylase_inhib PF01356.19 EEB08861.1 - 0.2 11.7 0.4 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase inhibitor NUC153 PF08159.12 EEB08862.1 - 3.8e-10 39.4 1.4 7e-10 38.5 1.4 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 EEB08862.1 - 4e-06 27.0 0.0 9.2e-05 22.7 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB08862.1 - 0.0012 19.6 1.3 1.2e+02 3.8 0.0 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat Pox_MCEL PF03291.16 EEB08863.1 - 1.3e-93 313.7 0.0 2.1e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EEB08863.1 - 8.3e-14 52.1 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB08863.1 - 3.9e-11 43.0 0.0 6.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB08863.1 - 6.1e-07 30.0 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08863.1 - 2.7e-06 27.3 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08863.1 - 8.7e-06 26.4 0.0 2.2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEB08863.1 - 0.051 13.1 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EEB08863.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 EEB08863.1 - 0.13 12.2 0.3 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RCC1 PF00415.18 EEB08864.1 - 4e-24 85.0 1.7 8.7e-06 26.3 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EEB08864.1 - 7.1e-13 48.8 1.9 3.2e-08 33.8 0.1 3.3 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EEB08864.1 - 2.2e-09 37.7 0.3 5.5e-07 30.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) RCC1_2 PF13540.6 EEB08864.1 - 5.5e-08 32.4 13.4 1.2e-05 24.9 0.9 4.8 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 EEB08864.1 - 1.4e-07 32.0 0.2 3.4e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEB08864.1 - 5.5e-07 29.7 0.1 0.0041 17.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEB08864.1 - 3.8e-05 23.7 0.2 0.021 15.3 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EEB08864.1 - 0.0013 19.0 0.0 0.6 10.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DUF5006 PF16397.5 EEB08864.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) LMBR1 PF04791.16 EEB08864.1 - 3.5 6.4 10.9 3.9 6.3 9.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein PAP1 PF08601.10 EEB08865.1 - 1.9e-14 54.2 0.5 1.9e-14 54.2 0.5 4.9 2 1 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 EEB08865.1 - 2e-07 31.0 17.0 4.9e-07 29.7 17.0 1.7 1 1 0 1 1 1 1 bZIP transcription factor Spc29 PF17082.5 EEB08865.1 - 0.00082 19.3 1.8 0.0015 18.4 1.8 1.5 1 0 0 1 1 1 1 Spindle Pole Component 29 Cep57_CLD PF14073.6 EEB08865.1 - 0.059 13.4 10.9 0.12 12.4 10.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Shugoshin_N PF07558.11 EEB08865.1 - 0.076 12.9 0.5 0.076 12.9 0.5 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TMCO5 PF14992.6 EEB08865.1 - 0.18 11.4 6.4 0.31 10.6 6.4 1.3 1 0 0 1 1 1 0 TMCO5 family Rab_bind PF16704.5 EEB08865.1 - 0.22 11.6 5.1 0.63 10.1 5.1 1.8 1 0 0 1 1 1 0 Rab binding domain DUF16 PF01519.16 EEB08865.1 - 1.7 9.2 7.2 17 5.9 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.9 EEB08865.1 - 2.3 8.4 12.8 4.1 7.6 12.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.15 EEB08865.1 - 3.6 7.8 18.4 40 4.4 1.5 2.3 1 1 1 2 2 2 0 Basic region leucine zipper SNF2_N PF00176.23 EEB08866.2 - 1.5e-63 214.6 0.0 2.5e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EEB08866.2 - 3e-22 78.3 0.5 2.1e-13 49.9 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EEB08866.2 - 7e-19 68.2 0.0 2.1e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08866.2 - 3.5e-09 36.9 0.0 1.5e-08 34.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EEB08866.2 - 3.5e-08 33.8 0.6 3.5e-08 33.8 0.6 4.6 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 DEAD PF00270.29 EEB08866.2 - 0.00022 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDH1_2_SANT_HL1 PF18375.1 EEB08866.2 - 0.00081 20.0 0.6 0.00081 20.0 0.6 2.6 3 0 0 3 3 3 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 EEB08866.2 - 0.11 12.5 5.4 0.61 10.1 0.0 2.8 2 0 0 2 2 2 0 SLIDE CHDCT2 PF08074.11 EEB08866.2 - 0.25 11.5 3.0 0.4 10.8 0.0 2.9 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain SIR2 PF02146.17 EEB08867.2 - 1.2e-28 100.3 0.0 2.9e-28 99.0 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 EEB08867.2 - 0.053 13.7 0.5 0.14 12.3 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain 5_3_exonuc PF01367.20 EEB08868.1 - 0.057 14.0 1.2 0.22 12.1 0.8 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Hox9_act PF04617.13 EEB08868.1 - 0.11 13.2 2.3 20 5.9 1.6 2.3 2 0 0 2 2 2 0 Hox9 activation region ATG16 PF08614.11 EEB08868.1 - 0.53 10.5 11.8 1.1 9.4 11.8 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Acyltransferase PF01553.21 EEB08869.1 - 1.7e-07 30.9 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase FAD_binding_1 PF00667.20 EEB08870.1 - 4.3e-33 114.8 0.0 6.5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEB08870.1 - 2.7e-12 47.3 0.0 5.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-PARP PF00645.18 EEB08871.1 - 1.2e-19 70.9 0.0 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Sec10 PF07393.11 EEB08872.1 - 4e-129 432.1 10.9 4e-129 432.1 10.9 1.5 1 1 1 2 2 2 1 Exocyst complex component Sec10 YMF19 PF02326.15 EEB08872.1 - 0.58 11.0 9.2 2.1 9.2 0.2 4.4 4 0 0 4 4 4 0 Plant ATP synthase F0 Ribonuc_2-5A PF06479.12 EEB08872.1 - 5.1 7.3 8.6 4.7 7.4 0.0 3.9 3 1 1 4 4 4 0 Ribonuclease 2-5A Thioredoxin PF00085.20 EEB08874.1 - 6.2e-22 77.5 0.2 1.8e-21 76.0 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEB08874.1 - 8e-07 29.5 0.1 2.6e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EEB08874.1 - 5.2e-06 26.4 0.0 8.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EEB08874.1 - 8.2e-06 26.1 1.8 0.063 13.6 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EEB08874.1 - 0.0051 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EEB08874.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family BA14K PF07886.11 EEB08874.1 - 0.025 14.4 0.4 0.061 13.2 0.4 1.7 1 0 0 1 1 1 0 BA14K-like protein Redoxin PF08534.10 EEB08874.1 - 0.097 12.4 0.3 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Redoxin Thioredoxin_9 PF14595.6 EEB08874.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Vta1 PF04652.16 EEB08875.1 - 9.5e-30 103.5 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 EEB08875.1 - 6.8e-17 60.9 2.8 7.9e-17 60.7 0.3 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain Fe-ADH PF00465.19 EEB08876.1 - 1.3e-55 188.8 1.4 1.6e-55 188.4 1.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EEB08876.1 - 8.9e-35 120.6 1.3 1.2e-34 120.2 1.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EEB08876.1 - 4.6e-06 26.0 0.5 1.1e-05 24.7 0.5 1.6 1 1 0 1 1 1 1 3-dehydroquinate synthase Aldolase PF01081.19 EEB08876.1 - 0.055 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase PFK PF00365.20 EEB08876.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 Phosphofructokinase MBOAT PF03062.19 EEB08877.1 - 1.7e-34 119.7 30.5 7e-34 117.7 29.9 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EEB08877.1 - 8.3e-05 22.8 1.9 8.3e-05 22.8 1.9 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Pal1 PF08316.11 EEB08878.2 - 5.4e-28 98.5 2.5 8.4e-26 91.4 0.7 2.8 1 1 1 2 2 2 2 Pal1 cell morphology protein Arrestin_C PF02752.22 EEB08879.1 - 1.4e-10 41.8 4.4 1.3e-09 38.6 0.8 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 EEB08879.1 - 0.0086 15.3 2.0 0.093 11.9 0.6 2.7 2 1 1 3 3 3 1 Rgp1 fn3_5 PF06280.12 EEB08879.1 - 0.04 14.6 0.6 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Fn3-like domain Autophagy_act_C PF03987.15 EEB08879.1 - 0.072 13.7 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain Arrestin_N PF00339.29 EEB08879.1 - 0.23 11.5 1.4 4.2 7.4 0.1 2.9 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 EEB08880.1 - 1.8e-35 122.6 0.0 2.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08880.1 - 6.3e-28 97.8 0.0 8.7e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB08880.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EEB08880.1 - 0.13 12.1 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family PMT PF02366.18 EEB08881.2 - 5e-85 285.0 20.6 5e-85 285.0 20.6 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEB08881.2 - 8.3e-59 198.5 9.8 8.3e-59 198.5 9.8 3.0 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEB08881.2 - 2.3e-16 60.2 0.0 4.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain GATase_2 PF00310.21 EEB08882.1 - 9.6e-180 597.8 0.0 1.4e-179 597.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EEB08882.1 - 2.2e-156 520.6 0.0 1.1e-154 515.0 0.0 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EEB08882.1 - 2.1e-115 385.0 0.0 3.8e-113 377.6 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EEB08882.1 - 2.2e-87 291.6 3.1 3.8e-87 290.8 3.1 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EEB08882.1 - 2.4e-26 92.7 0.0 8e-26 90.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EEB08882.1 - 1.2e-22 79.8 0.0 2.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 EEB08882.1 - 3.2e-08 33.2 0.5 0.00089 18.6 0.0 3.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEB08882.1 - 1.1e-07 31.9 0.0 3.9e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEB08882.1 - 1.3e-07 31.5 0.3 0.00024 20.8 0.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEB08882.1 - 5.5e-06 26.8 1.0 0.00021 21.8 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEB08882.1 - 8.9e-06 25.1 0.2 3.1e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EEB08882.1 - 2.8e-05 23.6 0.2 8.6e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EEB08882.1 - 5e-05 22.6 0.1 0.00021 20.5 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EEB08882.1 - 9.2e-05 21.8 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEB08882.1 - 0.00018 21.0 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEB08882.1 - 0.00029 19.6 1.7 0.00031 19.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 EEB08882.1 - 0.00062 20.2 0.2 0.096 13.1 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EEB08882.1 - 0.028 14.4 0.0 0.54 10.2 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EEB08882.1 - 0.061 12.4 0.2 0.14 11.1 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EEB08882.1 - 0.14 11.4 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 EEB08882.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Trp_halogenase PF04820.14 EEB08882.1 - 0.16 10.8 0.1 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase MADF_DNA_bdg PF10545.9 EEB08882.1 - 0.2 12.0 0.3 0.73 10.2 0.3 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GIDA PF01134.22 EEB08882.1 - 0.44 9.6 3.1 0.57 9.2 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A FMN_dh PF01070.18 EEB08882.1 - 3.3 6.6 9.2 0.07 12.1 1.9 1.9 3 0 0 3 3 2 0 FMN-dependent dehydrogenase HSP70 PF00012.20 EEB08883.1 - 1.1e-262 872.6 3.6 1.2e-262 872.4 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB08883.1 - 3.2e-16 59.1 0.0 6.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EEB08883.1 - 0.00031 20.5 0.0 0.00086 19.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EEB08883.1 - 0.069 12.4 1.3 0.11 11.7 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Cnd1_N PF12922.7 EEB08883.1 - 0.095 12.5 2.2 0.16 11.8 2.2 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Phage_Mu_F PF04233.14 EEB08883.1 - 1.6 9.5 3.9 32 5.3 1.2 2.9 2 1 0 2 2 2 0 Phage Mu protein F like protein Smg4_UPF3 PF03467.15 EEB08884.1 - 3.7e-36 124.7 0.4 3.7e-36 124.7 0.4 2.7 2 1 1 3 3 3 1 Smg-4/UPF3 family DUF5492 PF17596.2 EEB08884.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Macoilin PF09726.9 EEB08884.1 - 0.95 7.9 13.6 1.1 7.8 13.6 1.1 1 0 0 1 1 1 0 Macoilin family CNOT11 PF10155.9 EEB08885.1 - 0.023 14.9 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 SUR7 PF06687.12 EEB08886.1 - 7e-14 52.0 17.1 1.1e-13 51.3 17.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2569 PF10754.9 EEB08886.1 - 0.64 10.5 9.6 0.95 9.9 9.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF3611 PF12263.8 EEB08886.1 - 1.5 8.7 8.8 1.3 8.9 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) PAP2 PF01569.21 EEB08886.1 - 1.7 8.4 14.1 8.9 6.1 6.9 2.7 2 0 0 2 2 2 0 PAP2 superfamily MCPVI PF02993.14 EEB08886.1 - 8.7 6.1 9.8 0.3 10.9 3.4 1.9 2 0 0 2 2 2 0 Minor capsid protein VI MBOAT PF03062.19 EEB08887.1 - 2.8e-46 158.5 19.5 2.8e-46 158.5 19.5 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EEB08887.1 - 0.00061 20.0 4.5 0.0017 18.6 4.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PAPS_reduct PF01507.19 EEB08888.1 - 2e-43 148.4 0.0 2.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.32 EEB08890.1 - 4.6e-20 71.6 1.7 0.0024 18.6 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08890.1 - 1.9e-08 34.5 0.0 0.045 14.1 0.0 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EEB08890.1 - 0.00019 21.3 0.1 0.068 12.9 0.0 2.4 2 0 0 2 2 2 2 TUP1-like enhancer of split Nup160 PF11715.8 EEB08890.1 - 0.066 11.8 0.0 0.14 10.8 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ADH_N PF08240.12 EEB08891.2 - 7.4e-27 93.4 4.2 1.3e-26 92.6 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEB08891.2 - 1.1e-11 44.8 0.0 5.3e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EEB08891.2 - 4.4e-10 39.3 0.3 8.8e-10 38.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 EEB08891.2 - 0.056 12.8 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ResIII PF04851.15 EEB08892.2 - 1.7e-27 96.5 0.1 9.5e-27 94.1 0.0 2.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEB08892.2 - 2.6e-18 66.4 0.1 1.1e-16 61.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEB08892.2 - 1.9e-14 53.8 0.1 4.8e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEB08892.2 - 1.5e-06 28.1 0.1 2.3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EEB08892.2 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EEB08892.2 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TruB_N PF01509.18 EEB08893.1 - 4.7e-43 147.1 0.0 5.5e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EEB08893.1 - 4.1e-05 23.6 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 EEB08893.1 - 0.06 13.4 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 RNA pseudouridylate synthase Ribosomal_L5e PF17144.4 EEB08894.1 - 2.5e-79 265.0 0.0 3.9e-79 264.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EEB08894.1 - 5.3e-33 113.8 5.0 5.3e-33 113.8 5.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EEB08894.1 - 0.019 15.3 1.9 0.059 13.7 0.0 2.3 2 1 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 EEB08894.1 - 0.026 14.7 0.5 0.31 11.3 0.1 2.5 2 1 1 3 3 3 0 Threonine synthase N terminus His_Phos_2 PF00328.22 EEB08895.1 - 2.6e-51 175.2 0.0 3.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.24 EEB08896.1 - 1.1e-125 420.1 26.9 1.3e-125 419.8 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB08896.1 - 1.6e-18 66.7 52.3 1.2e-17 63.9 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily U3_assoc_6 PF08640.11 EEB08897.1 - 5.9e-29 100.0 3.5 1.3e-28 98.8 3.5 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EEB08897.1 - 0.014 16.1 0.5 6.6 7.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LAGLIDADG_WhiA PF14527.6 EEB08897.1 - 0.17 12.0 2.9 0.5 10.5 2.9 1.8 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Coatomer_WDAD PF04053.14 EEB08898.1 - 4.2e-151 504.0 1.0 9.5e-151 502.8 0.1 2.0 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EEB08898.1 - 1.1e-36 124.1 14.6 2.7e-05 24.9 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08898.1 - 6.6e-08 32.7 0.4 1.9 8.9 0.0 6.5 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB08898.1 - 0.014 15.3 1.6 0.89 9.4 0.0 3.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 EEB08898.1 - 0.055 13.4 0.5 3.5 7.7 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat PG_binding_2 PF08823.11 EEB08898.1 - 0.083 13.2 0.4 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 Putative peptidoglycan binding domain RRM_1 PF00076.22 EEB08899.1 - 3.5e-12 46.0 0.0 5.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB08899.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3275 PF11679.8 EEB08899.1 - 7.2 6.5 12.6 13 5.7 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RIC3 PF15361.6 EEB08900.1 - 0.004 17.6 0.0 0.0046 17.4 0.0 1.3 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 GPI-anchored PF10342.9 EEB08901.2 - 1.4e-18 67.4 5.6 1.4e-18 67.4 5.6 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFCD_C PF12612.8 EEB08902.2 - 1.3e-07 31.7 3.8 1.6e-07 31.3 0.1 3.1 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 EEB08902.2 - 0.0028 17.8 0.7 1.1 9.4 0.0 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EEB08902.2 - 0.0043 17.4 1.3 1.5 9.2 0.0 4.3 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EEB08902.2 - 0.28 11.5 15.5 0.89 10.0 0.0 6.7 8 0 0 8 8 8 0 HEAT repeat MAP65_ASE1 PF03999.12 EEB08903.1 - 0.008 14.9 0.9 0.0088 14.8 0.9 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Ndc80_HEC PF03801.13 EEB08904.1 - 2.6e-51 173.3 0.0 1.4e-50 170.9 0.0 2.1 1 1 1 2 2 2 1 HEC/Ndc80p family Spc7 PF08317.11 EEB08904.1 - 1.6e-05 24.0 40.2 7.8e-05 21.7 19.4 2.8 2 1 0 2 2 2 2 Spc7 kinetochore protein UPF0242 PF06785.11 EEB08904.1 - 0.00061 19.9 45.0 0.096 12.8 15.5 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0242) N-terminus CALCOCO1 PF07888.11 EEB08904.1 - 0.0011 18.0 17.3 0.0011 18.0 17.3 2.1 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5595 PF18077.1 EEB08904.1 - 0.0042 17.1 2.8 0.0042 17.1 2.8 5.5 6 1 1 7 7 7 1 Domain of unknown function (DUF5595) Golgin_A5 PF09787.9 EEB08904.1 - 0.0046 16.5 2.0 0.0046 16.5 2.0 3.3 2 1 1 3 3 3 2 Golgin subfamily A member 5 DUF812 PF05667.11 EEB08904.1 - 0.017 14.0 45.2 0.065 12.1 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF812) APG6_N PF17675.1 EEB08904.1 - 0.027 15.0 46.9 3.6 8.1 16.1 4.4 2 1 1 3 3 3 0 Apg6 coiled-coil region PKHD_C PF18331.1 EEB08904.1 - 0.49 10.5 2.7 1.7 8.8 0.2 2.9 3 0 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain FlaC_arch PF05377.11 EEB08904.1 - 1 9.8 31.1 0.56 10.6 0.5 6.4 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 EEB08904.1 - 1.2 7.5 2.8 0.87 8.0 0.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 EEB08904.1 - 2.1 9.3 36.0 7.4 7.5 10.1 4.1 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4618 PF15397.6 EEB08904.1 - 2.5 7.4 39.4 0.99 8.8 9.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 EEB08904.1 - 3 7.1 24.7 1.4 8.2 3.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EEB08904.1 - 4.5 7.3 28.1 7.7 6.6 0.3 4.3 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 EEB08904.1 - 4.9 6.5 43.0 2.5 7.4 15.1 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HSBP1 PF06825.12 EEB08904.1 - 6 6.8 18.9 1.8 8.5 0.1 5.2 6 0 0 6 6 6 0 Heat shock factor binding protein 1 FCH PF00611.23 EEB08905.2 - 2.4e-14 53.4 0.6 7.8e-14 51.7 0.6 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EEB08905.2 - 1.8e-10 40.2 0.1 3.3e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB08905.2 - 1.2e-09 37.9 0.1 2e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB08905.2 - 1.4e-08 34.3 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF848 PF05852.11 EEB08905.2 - 0.19 11.8 1.7 1.3 9.2 0.2 2.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) PLC-beta_C PF08703.10 EEB08905.2 - 1.3 9.0 8.7 0.15 12.1 0.5 2.5 2 1 1 3 3 3 0 PLC-beta C terminal CTD_bind PF04818.13 EEB08907.1 - 0.0033 18.2 0.2 0.011 16.5 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CH PF00307.31 EEB08908.1 - 6.8e-06 26.2 1.3 0.00022 21.4 0.0 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain PhoLip_ATPase_N PF16209.5 EEB08908.1 - 0.36 10.5 3.1 0.84 9.4 0.2 3.0 3 0 0 3 3 3 0 Phospholipid-translocating ATPase N-terminal DEAD PF00270.29 EEB08909.1 - 1.5e-50 171.4 0.0 8.4e-50 169.0 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB08909.1 - 2.2e-31 108.5 0.1 6e-29 100.6 0.1 3.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08909.1 - 2.7e-06 27.5 1.5 7.2e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEB08909.1 - 0.0014 18.9 0.2 0.011 16.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain CMS1 PF14617.6 EEB08909.1 - 0.0093 15.3 0.0 0.0093 15.3 0.0 3.4 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Senescence PF06911.12 EEB08909.1 - 0.091 13.1 14.0 0.19 12.0 14.0 1.5 1 0 0 1 1 1 0 Senescence-associated protein CAC1F_C PF16885.5 EEB08909.1 - 9.2 5.8 11.3 13 5.3 11.3 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term RRN9 PF10680.9 EEB08911.1 - 7.9 6.9 12.4 2.3e+02 2.1 9.5 3.4 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RNase_PH PF01138.21 EEB08912.1 - 1.4e-21 77.4 0.0 2.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEB08912.1 - 7.2e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Diphthamide_syn PF01866.17 EEB08913.1 - 4.9e-91 305.3 0.0 6.1e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3020 PF11223.8 EEB08914.1 - 4.2e-22 78.4 7.5 4.2e-22 78.4 7.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) WD40 PF00400.32 EEB08915.1 - 3.3e-10 40.4 4.8 0.015 16.2 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat RPN2_C PF18004.1 EEB08916.1 - 3e-49 167.0 6.7 3e-49 167.0 6.7 1.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EEB08916.1 - 2.3e-37 125.5 27.6 9.5e-07 29.0 0.1 9.0 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EEB08916.1 - 3e-14 53.2 4.7 1.3e-10 41.6 0.4 4.3 3 1 1 5 5 5 2 HEAT repeats Cnd3 PF12719.7 EEB08916.1 - 0.00075 18.8 0.3 0.018 14.2 0.0 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EEB08916.1 - 0.0021 18.5 0.1 0.02 15.4 0.0 2.9 2 0 0 2 2 2 1 HEAT-like repeat Vfa1 PF08432.10 EEB08916.1 - 0.0048 17.3 8.6 0.62 10.4 6.7 2.3 2 0 0 2 2 2 2 AAA-ATPase Vps4-associated protein 1 HEAT_PBS PF03130.16 EEB08916.1 - 0.016 15.8 0.8 9.9 7.2 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT PF02985.22 EEB08916.1 - 0.027 14.7 2.2 0.55 10.6 0.2 4.0 4 0 0 4 4 4 0 HEAT repeat DUF913 PF06025.12 EEB08916.1 - 0.67 8.9 5.0 1.7 7.6 5.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MSA_2 PF00985.17 EEB08916.1 - 1.9 8.9 7.8 3.5 8.0 7.8 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family RR_TM4-6 PF06459.12 EEB08916.1 - 3.5 7.4 9.5 6.3 6.5 9.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IMS PF00817.20 EEB08917.2 - 1.3e-47 161.6 1.1 2.8e-47 160.5 0.4 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EEB08917.2 - 6.3e-19 68.8 0.3 1.8e-18 67.3 0.2 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EEB08917.2 - 4.7e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 EEB08917.2 - 0.0024 18.3 0.0 0.13 12.7 0.0 2.8 3 0 0 3 3 3 1 Barrier to autointegration factor mCpol PF18182.1 EEB08917.2 - 0.11 12.9 2.5 0.82 10.0 0.0 3.4 4 0 0 4 4 4 0 minimal CRISPR polymerase domain Ribophorin_II PF05817.14 EEB08918.2 - 1.9e-11 43.3 0.1 2.5e-11 42.9 0.1 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S8 PF00410.19 EEB08919.1 - 5.8e-15 55.4 0.0 2.2e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 Translin PF01997.16 EEB08920.1 - 1.1e-47 162.7 0.1 1.4e-47 162.3 0.1 1.2 1 0 0 1 1 1 1 Translin family PIN_8 PF18476.1 EEB08920.1 - 0.22 11.3 2.3 0.21 11.4 0.3 1.8 2 0 0 2 2 2 0 PIN like domain LAG1-DNAbind PF09271.11 EEB08921.1 - 4.3e-22 79.4 5.2 1.6e-19 71.1 5.2 2.6 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EEB08921.1 - 8e-13 48.9 0.0 2.4e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4588 PF15251.6 EEB08921.1 - 0.00073 19.4 2.5 0.0025 17.6 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) DUF3835 PF12927.7 EEB08922.1 - 1.4e-14 54.7 0.7 1.4e-14 54.7 0.7 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF3835) Scs3p PF10261.9 EEB08922.1 - 0.086 12.3 0.0 0.086 12.3 0.0 2.6 3 1 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM tRNA-synt_2 PF00152.20 EEB08923.1 - 1.8e-96 322.9 0.1 2.4e-96 322.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEB08923.1 - 0.0009 19.2 0.0 0.0024 17.8 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEB08923.1 - 0.0014 18.2 0.8 0.24 10.9 0.2 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Nod1 PF17114.5 EEB08923.1 - 0.043 14.0 0.4 0.096 12.8 0.4 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 tRNA-synt_2b PF00587.25 EEB08923.1 - 0.17 11.9 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_transf_34 PF05637.12 EEB08924.1 - 5.5e-72 242.3 1.5 9.1e-72 241.6 1.5 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_U49 PF10463.9 EEB08924.1 - 0.047 13.4 0.1 0.047 13.4 0.1 2.1 2 0 0 2 2 2 0 Peptidase U49 DUF3149 PF11346.8 EEB08924.1 - 0.066 12.8 1.8 0.13 12.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) CDC45 PF02724.14 EEB08924.1 - 7.4 4.7 24.9 11 4.2 24.9 1.2 1 0 0 1 1 1 0 CDC45-like protein UPF0016 PF01169.19 EEB08925.1 - 5.7e-39 132.3 24.1 1.4e-20 73.3 5.5 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EEB08925.1 - 3.5e-05 23.6 0.1 3.5e-05 23.6 0.1 3.0 3 1 0 3 3 3 1 Putative manganese efflux pump FmdE PF02663.14 EEB08925.1 - 0.015 15.3 0.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon NAD_Gly3P_dh_C PF07479.14 EEB08925.1 - 0.13 12.6 0.4 0.24 11.7 0.4 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus YEATS PF03366.16 EEB08926.1 - 1.4e-33 114.7 1.1 2.2e-33 114.0 1.1 1.3 1 0 0 1 1 1 1 YEATS family ILVD_EDD PF00920.21 EEB08927.1 - 2.4e-214 712.7 0.1 2.9e-214 712.5 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family Med20 PF08612.11 EEB08928.2 - 1.7e-16 60.3 0.6 4.4e-16 58.9 0.5 1.7 1 1 1 2 2 2 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex VbhA PF18495.1 EEB08928.2 - 0.44 10.4 2.2 1 9.3 2.2 1.6 1 0 0 1 1 1 0 Antitoxin VbhA P16-Arc PF04699.14 EEB08929.1 - 1.8e-43 148.6 0.0 2e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EEB08929.1 - 0.0047 17.2 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family CBFD_NFYB_HMF PF00808.23 EEB08930.2 - 6e-07 29.6 0.1 7.8e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 EEB08930.2 - 5.8e-05 23.2 0.0 6.9e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 CENP-W protein TIP49_C PF17856.1 EEB08930.2 - 0.017 15.3 0.1 0.03 14.5 0.1 1.4 1 0 0 1 1 1 0 TIP49 AAA-lid domain PUF PF00806.19 EEB08931.2 - 7.2e-57 186.0 13.5 2.7e-08 33.0 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Peptidase_M28 PF04389.17 EEB08932.1 - 7.1e-38 130.3 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEB08932.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 GH3 PF03321.13 EEB08932.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DUF2273 PF10031.9 EEB08932.1 - 0.024 14.6 2.5 0.1 12.6 2.5 2.1 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF676 PF05057.14 EEB08933.1 - 5.7e-46 156.8 0.0 9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EEB08933.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) COQ7 PF03232.13 EEB08933.1 - 0.11 12.3 0.5 0.19 11.5 0.5 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 TFIIS_C PF01096.18 EEB08934.1 - 6.1e-17 61.2 1.1 6.1e-17 61.2 1.1 3.1 3 1 1 4 4 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEB08934.1 - 3.3e-15 55.6 8.7 1.2e-11 44.2 0.5 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 EEB08934.1 - 3.1e-05 23.9 8.6 0.0022 18.0 0.6 2.8 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 EEB08934.1 - 0.00051 19.3 13.4 0.014 14.7 1.2 3.6 3 1 0 3 3 3 2 zinc-ribbon domain zf-TFIIB PF13453.6 EEB08934.1 - 0.0017 17.6 7.7 0.0024 17.2 1.0 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger VP_N-CPKC PF11475.8 EEB08934.1 - 0.012 15.5 1.1 5.2 7.1 0.2 3.0 2 0 0 2 2 2 0 Virion protein N terminal domain C1_1 PF00130.22 EEB08934.1 - 0.017 15.0 0.6 0.017 15.0 0.6 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RecR PF02132.15 EEB08934.1 - 0.024 14.2 0.6 0.024 14.2 0.6 2.9 3 0 0 3 3 3 0 RecR protein zf-H2C2_2 PF13465.6 EEB08934.1 - 0.069 13.6 0.1 0.069 13.6 0.1 3.5 4 0 0 4 4 3 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 EEB08934.1 - 0.078 12.9 10.9 22 5.1 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 EEB08934.1 - 0.11 12.5 9.5 2.1 8.4 1.2 2.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 EEB08934.1 - 0.13 12.3 9.7 0.16 12.0 2.3 3.2 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.14 EEB08934.1 - 0.18 11.7 14.3 0.87 9.5 0.7 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Prok-RING_1 PF14446.6 EEB08934.1 - 0.31 11.0 4.9 4.9 7.2 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 EEB08934.1 - 0.34 10.5 12.3 3 7.4 4.0 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding Baculo_LEF5_C PF11792.8 EEB08934.1 - 0.54 10.0 5.6 3.8 7.3 0.0 3.4 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain zf_UBZ PF18439.1 EEB08934.1 - 0.68 9.6 14.0 5.4 6.7 0.4 4.2 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 EEB08934.1 - 0.72 9.6 15.3 2.5 7.9 1.6 3.5 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EEB08934.1 - 0.75 10.6 9.3 0.44 11.3 0.8 3.1 1 1 2 3 3 3 0 zinc-ribbon family zf-Di19 PF05605.12 EEB08934.1 - 0.79 10.1 7.3 14 6.0 2.1 3.1 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S27e PF01667.17 EEB08934.1 - 0.82 9.4 0.1 0.82 9.4 0.1 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 zf-RRN7 PF11781.8 EEB08934.1 - 1.3 8.8 8.1 6.3 6.6 0.0 3.8 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nudix_N_2 PF14803.6 EEB08934.1 - 1.4 8.9 11.7 8.5 6.4 3.3 3.8 2 2 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 EEB08934.1 - 1.6 8.9 14.4 6.6 6.9 0.8 3.4 2 2 0 3 3 3 0 Zinc ribbon domain DUF1610 PF07754.11 EEB08934.1 - 1.9 8.5 11.1 3.9 7.5 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) PHD PF00628.29 EEB08934.1 - 2.1 8.3 9.5 0.39 10.7 0.7 2.9 2 1 0 2 2 2 0 PHD-finger Lar_restr_allev PF14354.6 EEB08934.1 - 2.2 8.7 10.5 3.7 8.0 2.3 2.7 2 2 0 2 2 2 0 Restriction alleviation protein Lar NOB1_Zn_bind PF08772.11 EEB08934.1 - 3.2 8.0 9.9 13 6.1 1.3 2.9 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF35_N PF12172.8 EEB08934.1 - 3.7 7.5 6.5 7.7 6.5 0.0 3.5 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PADR1 PF08063.12 EEB08934.1 - 5 7.0 10.8 3.4 7.5 0.1 3.7 3 1 1 4 4 4 0 PADR1 (NUC008) domain PhnA_Zn_Ribbon PF08274.12 EEB08934.1 - 5.3 7.1 13.7 14 5.7 0.4 3.8 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Ogr_Delta PF04606.12 EEB08934.1 - 5.5 7.1 8.3 0.15 12.1 1.0 2.2 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf_C2H2_10 PF18414.1 EEB08934.1 - 6.7 6.3 9.3 5 6.8 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-C2H2_4 PF13894.6 EEB08934.1 - 7.2 7.7 12.2 38 5.5 0.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Mss51 PF13824.6 EEB08934.1 - 7.6 6.7 9.8 1.2e+02 2.9 9.8 2.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C4_Topoisom PF01396.19 EEB08934.1 - 9 6.2 14.6 3 7.7 6.0 3.7 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF2757 PF10955.8 EEB08934.1 - 9.9 6.5 7.6 9.5 6.6 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) DUF1729 PF08354.10 EEB08935.2 - 2.3e-117 391.9 0.0 3.9e-117 391.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EEB08935.2 - 2.6e-70 237.5 0.0 4.3e-69 233.5 0.0 2.6 2 1 1 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 EEB08935.2 - 1.9e-41 141.3 0.0 4.9e-41 140.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EEB08935.2 - 1.4e-31 109.2 0.1 3e-31 108.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EEB08935.2 - 1.3e-26 92.5 1.2 4.7e-26 90.8 0.1 2.5 3 0 0 3 3 3 1 MaoC like domain SAT PF16073.5 EEB08935.2 - 1.2e-24 87.4 0.0 2.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EEB08935.2 - 1.9e-18 66.9 0.0 4.3e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase SH3_14 PF18343.1 EEB08935.2 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Dda helicase SH3 domain Brix PF04427.18 EEB08936.1 - 2e-39 135.7 0.2 3.1e-39 135.1 0.2 1.3 1 0 0 1 1 1 1 Brix domain URO-D PF01208.17 EEB08937.1 - 1e-130 435.9 0.0 1.2e-130 435.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) cNMP_binding PF00027.29 EEB08938.1 - 7.8e-30 102.8 0.1 1.4e-16 60.3 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EEB08938.1 - 6.8e-16 59.1 3.2 1.5e-14 54.7 3.2 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase Cupin_2 PF07883.11 EEB08938.1 - 0.13 12.0 0.1 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 Cupin domain DUF21 PF01595.20 EEB08939.2 - 8.5e-35 120.0 0.1 1.5e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EEB08939.2 - 0.0002 21.7 0.0 0.2 12.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain Dicty_REP PF05086.12 EEB08939.2 - 0.48 8.4 3.1 0.63 8.0 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EEB08939.2 - 0.8 8.3 5.3 1.1 7.9 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Got1 PF04178.12 EEB08940.1 - 7.5e-13 48.9 15.7 9e-13 48.6 15.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 EEB08940.1 - 0.15 12.4 17.3 0.037 14.3 10.4 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF981 PF06168.11 EEB08940.1 - 0.22 11.4 9.0 0.32 10.9 8.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF2157 PF09925.9 EEB08940.1 - 1.1 9.0 7.3 1.4 8.7 7.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF373 PF04123.13 EEB08940.1 - 1.9 7.8 4.4 2.2 7.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4199 PF13858.6 EEB08940.1 - 2.3 8.6 16.9 2.8 8.3 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Rhodanese PF00581.20 EEB08941.1 - 7.5e-24 84.3 0.0 7.2e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SNF2_N PF00176.23 EEB08942.1 - 8.6e-68 228.6 0.0 8.4e-66 222.1 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB08942.1 - 5.7e-19 68.5 0.0 2e-18 66.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08942.1 - 2.7e-05 24.2 0.0 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Phage_GPO PF05929.11 EEB08942.1 - 0.1 12.2 3.6 0.23 11.0 3.6 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase COG5 PF10392.9 EEB08942.1 - 0.12 12.6 3.0 0.38 10.9 2.2 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF16 PF01519.16 EEB08942.1 - 0.13 12.8 4.0 0.61 10.6 4.0 2.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Plasmid_RAQPRD PF09686.10 EEB08942.1 - 0.2 11.9 3.4 0.58 10.4 3.4 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4164 PF13747.6 EEB08942.1 - 0.46 10.8 9.7 1.5 9.2 9.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Snapin_Pallidin PF14712.6 EEB08942.1 - 0.62 10.5 6.9 4.6 7.7 1.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Allexi_40kDa PF05549.11 EEB08942.1 - 2.9 7.3 5.1 2.1 7.8 1.8 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein efThoc1 PF11957.8 EEB08943.1 - 1e-75 255.3 10.7 1e-75 255.3 10.7 2.1 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor APA3_viroporin PF11289.8 EEB08943.1 - 0.049 13.2 0.1 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 Coronavirus accessory protein 3a CHCH PF06747.13 EEB08944.1 - 5.5e-06 26.4 6.9 7.8e-06 25.9 6.9 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EEB08944.1 - 0.021 14.8 0.3 0.34 11.0 0.1 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CENP-B_dimeris PF09026.10 EEB08944.1 - 0.028 14.8 3.2 0.031 14.6 3.2 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRM_1 PF00076.22 EEB08945.1 - 6.4e-07 29.1 0.1 1.2e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB08945.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EEB08945.1 - 0.00026 20.8 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EEB08945.1 - 0.0038 17.2 0.0 0.009 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif DSHCT PF08148.12 EEB08946.2 - 8.6e-49 165.3 1.0 2.1e-48 164.1 1.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EEB08946.2 - 4.4e-33 113.9 0.0 1.1e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EEB08946.2 - 3.5e-22 79.6 2.9 7.3e-22 78.6 0.1 2.6 3 0 0 3 3 3 1 rRNA-processing arch domain DEAD PF00270.29 EEB08946.2 - 9.3e-18 64.6 0.0 2.7e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB08946.2 - 2.6e-06 27.7 0.0 2e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08946.2 - 0.00014 21.9 0.0 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HtaA PF04213.13 EEB08946.2 - 0.02 15.4 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Htaa GPI2 PF06432.11 EEB08947.1 - 1.3e-96 323.3 23.4 1.5e-96 323.1 23.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SMC_Nse1 PF07574.13 EEB08948.1 - 2e-19 70.2 1.5 2.5e-18 66.7 1.5 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EEB08948.1 - 0.053 13.8 16.1 0.1 12.9 16.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-LITAF-like PF10601.9 EEB08948.1 - 0.074 13.3 7.2 0.12 12.6 7.2 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain ANAPC2 PF08672.11 EEB08948.1 - 0.11 13.0 0.1 3 8.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 zf-RING_4 PF14570.6 EEB08948.1 - 2.9 7.7 14.6 1.8 8.4 11.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cpn60_TCP1 PF00118.24 EEB08950.1 - 2.6e-156 521.1 17.2 3e-156 520.9 17.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FecR PF04773.13 EEB08950.1 - 0.19 12.4 2.4 5.7 7.6 0.0 2.7 3 0 0 3 3 3 0 FecR protein ATP-synt_E PF05680.12 EEB08951.1 - 7.8e-11 42.2 0.3 9.7e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain Lant_dehydr_C PF14028.6 EEB08951.1 - 0.0035 16.9 0.2 0.004 16.7 0.2 1.0 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term DUF2605 PF10792.9 EEB08951.1 - 0.0038 17.1 0.9 0.0055 16.6 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2605) A_deaminase PF00962.22 EEB08952.1 - 2e-126 421.8 0.0 2.8e-126 421.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1776 PF08643.10 EEB08953.1 - 2.9e-37 128.7 0.0 2.3e-32 112.6 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) ParBc PF02195.18 EEB08954.1 - 4.1e-09 36.6 0.0 5.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Pkinase PF00069.25 EEB08955.2 - 7.7e-56 189.4 0.0 1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB08955.2 - 4.1e-27 95.1 0.1 4e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EEB08955.2 - 0.0038 16.9 0.3 0.0064 16.1 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EEB08955.2 - 0.007 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEB08955.2 - 0.014 14.2 1.0 0.027 13.2 0.2 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EEB08955.2 - 0.035 13.5 0.4 0.069 12.5 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB08955.2 - 0.042 13.5 0.1 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB08955.2 - 0.046 13.6 0.0 1.7 8.5 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family STT3 PF02516.14 EEB08956.2 - 8e-153 509.9 29.0 1.1e-152 509.4 29.0 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Phage_holin_5_2 PF16079.5 EEB08956.2 - 0.38 11.1 3.5 3 8.2 0.2 3.7 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V NIF PF03031.18 EEB08957.1 - 2.9e-23 82.4 0.2 5.2e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AAA_24 PF13479.6 EEB08957.1 - 0.006 16.3 1.0 0.015 15.0 1.0 1.8 1 1 0 1 1 1 1 AAA domain AbbA_antirepres PF14156.6 EEB08957.1 - 0.13 12.2 0.9 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Antirepressor AbbA Noelin-1 PF12308.8 EEB08957.1 - 0.13 12.3 2.2 2.6 8.1 0.5 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein zf-AN1 PF01428.16 EEB08958.1 - 2.4e-11 43.6 6.2 4.2e-11 42.8 6.2 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4667 PF15700.5 EEB08958.1 - 0.016 15.3 0.5 0.021 15.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Transp_Tc5_C PF04236.15 EEB08958.1 - 0.049 14.0 2.5 0.091 13.1 2.5 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain ubiquitin PF00240.23 EEB08958.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family DUF3123 PF11321.8 EEB08958.1 - 0.11 13.1 3.4 0.26 12.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DS PF01916.17 EEB08959.1 - 2.5e-132 440.5 0.0 2.9e-132 440.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Acetyltransf_1 PF00583.25 EEB08960.1 - 6.6e-21 74.7 0.1 8.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB08960.1 - 8e-14 51.7 0.1 9.5e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB08960.1 - 1.3e-12 48.0 0.1 1.7e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB08960.1 - 5.1e-10 39.2 0.1 7.4e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EEB08960.1 - 9.8e-07 28.6 0.0 4.2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB08960.1 - 1.9e-06 28.0 0.0 2.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEB08960.1 - 4.1e-06 27.5 0.0 4.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEB08960.1 - 5.9e-06 26.5 0.3 7.2e-06 26.2 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEB08960.1 - 0.0041 17.2 0.0 0.0041 17.2 0.0 2.1 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 EEB08960.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EEB08960.1 - 0.038 13.7 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ GNAT_acetyltran PF12746.7 EEB08960.1 - 0.062 12.9 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Sugar_tr PF00083.24 EEB08961.2 - 5.3e-30 104.7 30.8 9.4e-21 74.2 7.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEB08961.2 - 2.1e-18 66.4 43.1 6.3e-16 58.2 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EEB08962.1 - 3.5e-37 128.2 14.5 3.5e-37 128.2 14.5 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF21 PF01595.20 EEB08962.1 - 0.02 14.6 1.3 5.7 6.6 0.2 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DC_STAMP PF07782.13 EEB08962.1 - 0.97 9.2 6.1 0.093 12.5 0.6 1.9 2 0 0 2 2 2 0 DC-STAMP-like protein AA_permease_2 PF13520.6 EEB08963.1 - 4.6e-60 203.7 52.4 5.3e-60 203.4 52.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB08963.1 - 1.1e-16 60.6 35.9 1.4e-16 60.1 35.9 1.3 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.21 EEB08964.2 - 2.2e-121 405.3 24.7 2.5e-121 405.1 24.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 EEB08964.2 - 0.22 11.5 5.8 1.4 9.0 0.3 3.1 2 0 0 2 2 2 0 Bacteriophage P21 holin S TMEM107 PF14995.6 EEB08964.2 - 1.7 9.1 12.4 0.64 10.5 1.6 3.5 3 1 0 3 3 3 0 Transmembrane protein Cyclin_N PF00134.23 EEB08965.1 - 9.5e-46 154.7 0.1 4.9e-45 152.4 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB08965.1 - 6.6e-34 116.5 0.0 1.4e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Maf PF02545.14 EEB08965.1 - 0.052 13.4 0.9 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 Maf-like protein KH_1 PF00013.29 EEB08966.1 - 5e-07 29.4 0.1 0.00068 19.4 0.0 2.9 3 0 0 3 3 3 2 KH domain BRCT PF00533.26 EEB08967.1 - 1e-27 96.3 0.1 2.1e-06 28.0 0.0 5.6 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EEB08967.1 - 4.8e-24 84.1 3.1 4.9e-21 74.5 0.1 4.7 6 0 0 6 6 6 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EEB08967.1 - 1.5e-22 79.3 2.5 1.3e-14 53.9 0.0 4.6 5 0 0 5 5 5 2 twin BRCT domain BRCT_2 PF16589.5 EEB08967.1 - 2.7e-15 56.5 2.2 1.4e-05 25.4 0.1 6.1 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEB08967.1 - 2.1e-10 40.7 0.2 0.00042 20.5 0.1 4.4 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EEB08967.1 - 6.1e-06 26.2 0.3 1.6 8.9 0.3 5.1 5 1 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain EzrA PF06160.12 EEB08968.1 - 0.00022 19.6 18.0 0.00027 19.3 18.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SelB-wing_2 PF09106.11 EEB08968.1 - 0.053 13.7 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF3450 PF11932.8 EEB08968.1 - 1.3 8.2 16.9 1 8.6 10.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) RPN7 PF10602.9 EEB08969.1 - 2.6e-51 173.8 2.2 4.7e-51 172.9 2.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EEB08969.1 - 6.4e-16 58.8 0.0 2.3e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 PCI domain Cep57_CLD_2 PF14197.6 EEB08969.1 - 0.01 15.9 0.6 0.031 14.4 0.6 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HTH_DeoR PF08220.12 EEB08969.1 - 0.08 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Aminotran_1_2 PF00155.21 EEB08970.1 - 4.1e-37 128.2 0.0 5.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DDE_Tnp_IS66_C PF13817.6 EEB08970.1 - 0.034 14.4 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 0 IS66 C-terminal element PEX11 PF05648.14 EEB08971.2 - 5.2e-37 127.5 1.6 5.9e-37 127.3 1.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNF2_N PF00176.23 EEB08972.1 - 1.4e-71 241.1 3.0 6.7e-71 238.8 3.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEB08972.1 - 1e-17 64.4 0.3 4e-16 59.3 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB08972.1 - 2.4e-06 27.6 0.8 6.2e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DZR PF12773.7 EEB08972.1 - 0.13 12.3 2.2 0.31 11.1 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Nup84_Nup100 PF04121.13 EEB08973.1 - 7.8e-181 602.8 9.2 9.1e-181 602.6 9.2 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Aminotran_4 PF01063.19 EEB08974.2 - 1.3e-27 97.1 0.0 1.8e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV AAA PF00004.29 EEB08975.2 - 9.5e-09 35.8 0.0 2.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEB08975.2 - 0.013 15.5 0.0 0.14 12.1 0.0 2.4 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_22 PF13401.6 EEB08975.2 - 0.039 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EEB08975.2 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-RING_2 PF13639.6 EEB08976.2 - 2.1e-08 34.3 11.5 6.4e-07 29.6 12.6 2.3 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 EEB08976.2 - 3e-08 33.3 8.9 9.8e-07 28.5 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB08976.2 - 1e-06 28.6 1.5 3.4e-06 27.0 1.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EEB08976.2 - 3.6e-06 27.2 10.9 3.5e-05 24.0 11.6 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEB08976.2 - 4.6e-06 26.4 7.1 9.1e-06 25.5 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEB08976.2 - 5.6e-06 26.1 7.7 0.00044 20.0 2.9 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEB08976.2 - 1.2e-05 25.1 6.1 0.0051 16.6 3.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEB08976.2 - 3.2e-05 23.8 7.8 0.00062 19.7 9.0 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EEB08976.2 - 0.00024 20.8 2.4 0.019 14.7 0.5 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EEB08976.2 - 0.00027 20.9 5.1 0.0022 18.0 3.8 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger ATG22 PF11700.8 EEB08976.2 - 0.00093 17.9 4.8 0.077 11.6 0.0 2.3 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like zinc_ribbon_16 PF17034.5 EEB08976.2 - 0.018 15.3 2.2 0.028 14.6 0.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon like family DUF2721 PF11026.8 EEB08976.2 - 0.079 12.8 0.0 0.079 12.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Zn_ribbon_17 PF17120.5 EEB08976.2 - 0.38 10.4 6.7 0.043 13.4 2.1 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EEB08976.2 - 0.46 10.3 3.9 1.8 8.4 2.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EEB08976.2 - 1.6 8.6 4.0 4.7 7.1 4.0 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 EEB08976.2 - 3 7.9 9.9 0.31 11.1 4.4 2.2 2 0 0 2 2 2 0 Zinc-finger RINGv PF12906.7 EEB08976.2 - 3.7 7.7 7.3 2.8 8.2 4.1 2.1 2 0 0 2 2 2 0 RING-variant domain zf-P11 PF03854.14 EEB08976.2 - 8.6 6.1 14.2 0.86 9.3 0.1 2.8 3 0 0 3 3 2 0 P-11 zinc finger Pyr_redox_2 PF07992.14 EEB08977.2 - 7.9e-48 163.2 0.0 9.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEB08977.2 - 1.2e-09 38.6 0.0 4.1e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB08977.2 - 0.022 14.0 0.2 9.5 5.4 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4679 PF15728.5 EEB08977.2 - 0.37 9.8 8.0 0.72 8.8 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) RNase_PH PF01138.21 EEB08978.1 - 1.5e-19 70.8 0.1 2.5e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AFG1_ATPase PF03969.16 EEB08979.2 - 1.6e-82 277.3 0.2 1.4e-77 261.1 0.0 2.5 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EEB08979.2 - 1.1e-05 25.9 0.3 0.0025 18.2 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EEB08979.2 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EEB08979.2 - 0.062 13.6 0.1 0.52 10.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EEB08979.2 - 0.081 12.8 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EEB08979.2 - 0.092 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EEB08979.2 - 0.26 11.8 0.9 3.5 8.2 0.0 2.7 3 1 0 4 4 4 0 ABC transporter FKBP_C PF00254.28 EEB08980.2 - 6.3e-34 116.2 0.0 7.4e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FTHFS PF01268.19 EEB08981.1 - 9.7e-259 859.2 0.0 1.2e-258 858.9 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EEB08981.1 - 1.6e-69 232.3 2.0 2.2e-69 231.8 0.6 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EEB08981.1 - 3.1e-39 133.9 0.1 4.1e-38 130.2 0.1 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 EEB08981.1 - 0.025 14.6 0.0 0.24 11.5 0.0 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 EEB08982.1 - 2.5e-54 183.8 0.5 3.9e-54 183.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEB08982.1 - 2.6e-41 140.4 0.0 5.4e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEB08982.1 - 3.7e-14 52.9 1.5 3.7e-14 52.9 1.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB08982.1 - 0.00042 20.4 0.2 0.011 15.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EEB08982.1 - 0.025 14.4 0.8 0.083 12.8 0.8 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Methyltransf_31 PF13847.6 EEB08984.1 - 1.2e-21 77.1 0.0 1.8e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB08984.1 - 2.9e-09 37.5 0.0 4.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB08984.1 - 6.2e-09 36.5 0.1 9.1e-08 32.8 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB08984.1 - 1.1e-06 28.5 0.0 2.3e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEB08984.1 - 5.3e-06 26.1 0.0 2.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEB08984.1 - 2.6e-05 24.2 0.0 3.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB08984.1 - 3.9e-05 24.2 0.0 6.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 EEB08984.1 - 0.0026 17.0 0.0 0.0042 16.3 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EEB08984.1 - 0.0082 15.5 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EEB08984.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EEB08984.1 - 0.041 13.2 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CH PF00307.31 EEB08984.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain DREV PF05219.12 EEB08984.1 - 0.081 12.0 0.0 0.93 8.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase Ribosomal_L13 PF00572.18 EEB08985.1 - 3.4e-11 43.5 0.1 3e-09 37.2 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 RNA_pol_3_Rpc31 PF11705.8 EEB08986.1 - 7.2e-22 78.8 11.3 7.2e-22 78.8 11.3 1.5 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 EEB08986.1 - 5.2 6.1 14.4 8.3 5.4 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UAA PF08449.11 EEB08987.1 - 6.9e-46 156.8 15.8 8.5e-46 156.5 15.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EEB08987.1 - 3.6e-10 40.1 22.0 4.8e-10 39.7 7.7 3.0 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EEB08987.1 - 8.8e-06 25.1 4.8 0.02 14.1 1.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 EEB08987.1 - 0.003 16.9 15.0 0.015 14.6 15.1 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family RRM_1 PF00076.22 EEB08988.2 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.20 EEB08989.1 - 4.6e-10 39.1 4.2 4.6e-10 39.1 4.2 2.2 2 0 0 2 2 2 1 Ribosomal protein S21 PigN PF04987.14 EEB08990.1 - 2.3e-124 415.7 44.5 2.9e-124 415.4 44.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EEB08990.1 - 1.7e-07 31.2 2.6 1.6e-06 28.0 2.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEB08990.1 - 5e-06 26.1 0.1 7.4e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EEB08990.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EEB08990.1 - 0.09 12.9 0.3 0.21 11.7 0.1 1.6 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.20 EEB08990.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Rhodanese PF00581.20 EEB08991.1 - 8.9e-11 42.3 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain E1-E2_ATPase PF00122.20 EEB08992.1 - 1.5e-37 128.9 16.3 3.9e-31 108.0 0.1 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEB08992.1 - 1.8e-27 96.2 6.3 1.8e-27 96.2 6.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EEB08992.1 - 6.9e-20 70.9 0.0 1.9e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEB08992.1 - 8.4e-19 68.7 0.0 2.5e-17 63.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEB08992.1 - 8.8e-15 54.1 0.0 2.2e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEB08992.1 - 0.0035 17.1 1.7 0.0063 16.3 1.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEB08992.1 - 0.021 15.2 0.0 0.061 13.7 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S17e PF00833.18 EEB08994.1 - 1e-60 203.0 0.9 1.2e-60 202.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 DUF3016 PF11454.8 EEB08994.1 - 0.028 14.2 1.0 0.3 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3016) IpaB_EvcA PF03278.13 EEB08994.1 - 0.087 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IpaB/EvcA family HIT PF01230.23 EEB08995.1 - 2e-25 89.4 0.1 5.1e-25 88.1 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EEB08995.1 - 8.2e-09 36.0 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2415 PF10313.9 EEB08996.1 - 2.5e-11 43.3 0.0 1.1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 EEB08996.1 - 0.012 16.5 7.4 0.21 12.5 0.2 4.5 5 1 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB08996.1 - 0.056 13.7 0.0 7.3 7.0 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_A_exo1 PF01612.20 EEB08997.1 - 1e-16 61.2 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Aim21 PF11489.8 EEB08998.1 - 7.6e-11 41.7 60.6 3.7e-08 32.8 45.2 4.1 1 1 2 4 4 4 3 Altered inheritance of mitochondria protein 21 GREB1 PF15782.5 EEB08998.1 - 2.2 5.3 8.0 2.7 5.0 8.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 EEB08998.1 - 2.9 7.7 18.2 6.4 6.6 18.2 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosom_S12_S23 PF00164.25 EEB08999.2 - 5.9e-36 122.6 1.4 8.2e-36 122.1 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S21e PF01249.18 EEB09000.1 - 1.8e-40 136.9 0.1 2e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 EEB09000.1 - 0.03 14.2 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Elong_Iki1 PF10483.9 EEB09001.1 - 4.1e-45 154.5 0.2 6.4e-35 121.1 0.3 2.0 1 1 1 2 2 2 2 Elongator subunit Iki1 DUF835 PF05763.12 EEB09001.1 - 0.037 13.7 0.1 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF835) Ribosomal_L16 PF00252.18 EEB09002.1 - 2e-43 147.5 0.1 2.6e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CENP-K PF11802.8 EEB09003.1 - 8.9e-15 55.0 0.9 1.6e-14 54.1 0.9 1.5 1 1 0 1 1 1 1 Centromere-associated protein K Med9 PF07544.13 EEB09003.1 - 0.94 9.6 9.1 1.6 8.9 0.1 3.6 3 1 2 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_1_2 PF00155.21 EEB09004.2 - 3.2e-32 112.1 0.0 4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEB09004.2 - 0.00023 19.8 0.0 0.00037 19.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NARP1 PF12569.8 EEB09005.2 - 7.3e-48 163.7 4.0 7.3e-48 163.7 4.0 2.7 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EEB09005.2 - 6e-10 38.5 15.3 0.21 11.8 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09005.2 - 1.6e-05 25.3 13.2 1.4 9.5 0.0 5.7 4 2 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEB09005.2 - 4.9e-05 23.4 0.7 0.27 11.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB09005.2 - 8.9e-05 22.6 24.0 0.052 13.8 0.8 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EEB09005.2 - 0.00073 19.2 2.0 1.8 8.3 0.0 4.5 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 EEB09005.2 - 0.00086 19.9 1.6 0.27 11.9 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEB09005.2 - 0.0019 18.5 20.7 0.32 11.3 0.2 6.0 6 2 1 7 7 6 2 Tetratricopeptide repeat MRP-L46 PF11788.8 EEB09005.2 - 0.007 17.1 1.9 0.0074 17.0 0.1 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 TPR_1 PF00515.28 EEB09005.2 - 0.022 14.6 12.1 8.7 6.3 0.1 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 EEB09005.2 - 0.091 13.1 6.2 9.7 6.6 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EEB09005.2 - 0.12 12.9 2.4 11 6.4 0.3 3.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 EEB09005.2 - 0.76 10.0 6.8 2.1 8.6 0.4 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEB09005.2 - 4.4 8.4 12.1 3.2e+02 2.6 0.0 6.8 6 3 3 10 10 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB09005.2 - 5.2 7.9 10.2 18 6.3 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEB09006.1 - 4.1e-08 33.4 2.2 0.00035 20.8 0.4 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEB09006.1 - 1.5e-07 30.9 4.6 0.00033 20.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEB09006.1 - 1.8e-07 30.8 5.7 0.0034 17.5 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09006.1 - 3.2e-06 27.6 6.8 0.17 12.4 0.1 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EEB09006.1 - 1.1e-05 25.0 3.8 0.002 17.6 0.1 2.5 1 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 EEB09006.1 - 4.6e-05 23.0 4.3 0.0029 17.3 0.0 5.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEB09006.1 - 5.1e-05 23.4 0.1 2.4 8.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEB09006.1 - 0.00021 21.9 6.8 0.04 14.7 0.0 5.0 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEB09006.1 - 0.00026 20.8 1.9 0.033 14.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EEB09006.1 - 0.0057 16.4 8.2 0.037 13.7 0.2 3.1 1 1 3 4 4 4 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 EEB09006.1 - 0.0095 16.1 2.0 12 6.2 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EEB09006.1 - 0.052 13.4 5.5 0.79 9.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEB09006.1 - 0.056 14.1 4.6 1.6 9.5 0.1 4.0 4 1 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEB09006.1 - 0.22 11.2 4.7 5.7 6.7 0.0 4.8 7 0 0 7 7 7 0 TPR repeat TPR_16 PF13432.6 EEB09006.1 - 0.37 11.5 5.3 0.3 11.8 0.4 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EEB09006.1 - 2 9.3 0.0 2 9.3 0.0 3.4 5 0 0 5 5 2 0 Tetratricopeptide repeat UPF0020 PF01170.18 EEB09007.2 - 3.6e-07 30.1 0.0 9.1e-06 25.5 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EEB09007.2 - 0.0026 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 EEB09007.2 - 0.091 12.5 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 DNA methylase Peptidase_M22 PF00814.25 EEB09008.2 - 3.1e-85 286.2 0.0 3.6e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family MutL PF13941.6 EEB09008.2 - 0.1 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 MutL protein AAA_12 PF13087.6 EEB09009.2 - 3.7e-51 173.6 0.0 7.5e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 EEB09009.2 - 3.9e-42 144.4 0.0 8.7e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 EEB09009.2 - 2.1e-30 106.4 0.0 2.3e-14 53.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EEB09009.2 - 2.7e-11 43.5 0.0 7.5e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB09009.2 - 3.5e-09 37.1 0.0 9.7e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EEB09009.2 - 2.2e-07 31.1 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 EEB09009.2 - 6.8e-06 26.0 0.0 2.7e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 EEB09009.2 - 8.5e-06 25.5 0.9 0.00081 19.1 0.1 2.7 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 EEB09009.2 - 0.00015 21.6 0.1 0.55 9.9 0.1 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EEB09009.2 - 0.00091 18.8 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 EEB09009.2 - 0.013 15.6 0.2 0.032 14.3 0.2 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 EEB09009.2 - 0.043 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EEB09009.2 - 0.12 12.8 0.1 0.57 10.6 0.1 2.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EEB09009.2 - 0.18 11.1 0.1 0.59 9.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EEB09009.2 - 0.2 11.2 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EEB09009.2 - 0.23 10.4 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Alpha-amylase PF00128.24 EEB09010.2 - 1.6e-24 87.1 0.1 1.7e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EEB09010.2 - 2.2e-13 50.5 0.0 4.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EEB09010.2 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.6 EEB09010.2 - 0.00064 20.4 0.0 0.0048 17.6 0.1 2.3 2 0 0 2 2 2 1 Bacterial Ig-like domain Glyco_transf_4 PF13439.6 EEB09010.2 - 0.038 14.0 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Zip PF02535.22 EEB09011.1 - 1.2e-66 225.2 1.1 1.5e-66 224.9 1.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SIR2 PF02146.17 EEB09012.1 - 1.4e-64 217.3 0.0 2.4e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EEB09012.1 - 1.3e-05 25.0 0.1 0.0053 16.5 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EEB09012.1 - 0.21 11.3 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AAA_2 PF07724.14 EEB09013.2 - 1.3e-52 178.3 0.0 4.8e-51 173.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEB09013.2 - 4.7e-34 116.4 2.0 4.7e-34 116.4 2.0 3.2 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 EEB09013.2 - 1.9e-29 102.8 0.0 1e-15 58.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EEB09013.2 - 6e-24 83.9 0.5 2.3e-23 82.0 0.5 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EEB09013.2 - 1.1e-16 60.7 0.2 1.3e-07 31.6 0.0 3.5 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EEB09013.2 - 2.3e-16 60.1 0.2 3.7e-10 39.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EEB09013.2 - 1.5e-12 47.6 0.0 6.9e-08 32.4 0.0 2.7 2 1 1 3 3 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EEB09013.2 - 1.5e-12 48.2 3.6 3.5e-05 24.2 0.0 5.2 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EEB09013.2 - 1.1e-11 45.2 0.7 0.0012 19.2 0.0 4.8 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEB09013.2 - 3e-07 30.3 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EEB09013.2 - 4.7e-07 29.5 0.0 0.001 18.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 EEB09013.2 - 3.3e-06 26.6 0.0 0.033 13.6 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EEB09013.2 - 8.2e-06 26.4 0.0 0.11 13.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EEB09013.2 - 1.4e-05 24.9 0.0 0.0084 16.0 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEB09013.2 - 2.6e-05 24.0 0.5 1.7 8.4 0.0 4.3 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEB09013.2 - 3e-05 24.2 0.0 0.038 14.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEB09013.2 - 8.3e-05 22.4 0.0 0.26 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EEB09013.2 - 0.00011 22.5 0.0 0.72 10.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EEB09013.2 - 0.00018 21.8 0.3 2.3 8.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 EEB09013.2 - 0.00031 20.8 4.3 0.61 10.0 0.0 4.3 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea Torsin PF06309.11 EEB09013.2 - 0.00032 20.8 0.0 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_14 PF13173.6 EEB09013.2 - 0.00036 20.6 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EEB09013.2 - 0.00096 19.4 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EEB09013.2 - 0.00099 19.6 0.8 1.1 9.8 0.0 3.7 3 1 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.12 EEB09013.2 - 0.0027 17.0 0.8 2.6 7.3 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin RsgA_GTPase PF03193.16 EEB09013.2 - 0.0056 16.6 0.0 4.4 7.2 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 EEB09013.2 - 0.0067 15.6 0.0 5.6 6.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EEB09013.2 - 0.0073 16.0 0.3 10 6.0 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain TsaE PF02367.17 EEB09013.2 - 0.0083 16.1 0.0 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EEB09013.2 - 0.013 14.6 0.0 0.055 12.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 EEB09013.2 - 0.018 15.1 0.0 2.3 8.2 0.0 3.5 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 EEB09013.2 - 0.022 14.6 0.3 8.8 6.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EEB09013.2 - 0.026 14.1 0.8 2.9 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 EEB09013.2 - 0.03 13.8 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 EEB09013.2 - 0.036 14.0 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EEB09013.2 - 0.054 13.8 0.0 8.7 6.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain CbiA PF01656.23 EEB09013.2 - 0.075 13.1 0.0 17 5.5 0.0 3.3 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CHDCT2 PF08074.11 EEB09013.2 - 0.12 12.6 1.3 0.9 9.7 0.6 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain PEPCK_ATP PF01293.20 EEB09013.2 - 0.18 10.4 0.0 0.77 8.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase DUF5368 PF17336.2 EEB09013.2 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) MPS2 PF17060.5 EEB09013.2 - 0.37 10.0 5.2 0.65 9.2 5.2 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 Exonuc_VII_L PF02601.15 EEB09013.2 - 0.47 10.0 5.3 1 8.8 5.3 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EEB09013.2 - 0.6 7.9 1.8 0.9 7.4 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 EEB09013.2 - 1.1 9.7 0.0 1.1 9.7 0.0 4.5 3 1 0 3 3 2 0 AAA domain Spc7 PF08317.11 EEB09013.2 - 1.8 7.4 12.6 4.2 6.2 12.6 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 EEB09013.2 - 2.5 8.6 8.8 12 6.4 8.8 2.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_S13 PF00416.22 EEB09014.1 - 3.3e-53 179.4 2.5 3.8e-53 179.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EEB09014.1 - 0.009 14.8 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Period_C PF12114.8 EEB09014.1 - 0.009 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Period protein 2/3C-terminal region HHH_6 PF14579.6 EEB09014.1 - 0.013 15.7 0.5 0.091 13.0 0.1 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 EEB09014.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) dCMP_cyt_deam_1 PF00383.23 EEB09015.1 - 1.5e-12 47.3 0.1 3.6e-12 46.0 0.1 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEB09015.1 - 1.2e-08 34.8 0.1 5.6e-08 32.6 0.0 1.9 1 1 1 2 2 2 1 MafB19-like deaminase PRK PF00485.18 EEB09015.1 - 5.2e-08 32.9 0.0 1.2e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SNAD4 PF18750.1 EEB09015.1 - 1.7e-05 24.9 0.3 8.3e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 AAA_18 PF13238.6 EEB09015.1 - 0.00017 22.1 0.0 0.00035 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain APOBEC_N PF08210.11 EEB09015.1 - 0.001 19.0 0.1 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EEB09015.1 - 0.0029 17.7 0.0 0.0088 16.2 0.0 1.8 1 1 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 EEB09015.1 - 0.0034 17.3 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 APOBEC4-like -AID/APOBEC-deaminase NAD1 PF18778.1 EEB09015.1 - 0.007 16.5 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EEB09015.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 APOBEC2 Cytidylate_kin PF02224.18 EEB09015.1 - 0.012 15.3 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 EEB09015.1 - 0.019 15.1 0.0 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase-like family NAD2 PF18782.1 EEB09015.1 - 0.023 14.8 0.1 0.059 13.5 0.1 1.8 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 EEB09015.1 - 0.026 14.6 0.4 0.061 13.4 0.4 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase KTI12 PF08433.10 EEB09015.1 - 0.031 13.7 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EEB09015.1 - 0.039 14.4 0.2 0.69 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF2572 PF10833.8 EEB09015.1 - 0.049 13.4 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) PCNA_N PF00705.18 EEB09016.2 - 6.5e-60 200.4 3.9 1.3e-59 199.4 3.9 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EEB09016.2 - 5.2e-57 191.5 0.0 1.1e-56 190.5 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EEB09016.2 - 2.2e-07 30.6 0.2 2.7e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EEB09016.2 - 3.3e-06 26.4 1.9 0.00027 20.1 1.9 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EEB09016.2 - 0.00058 19.1 0.2 0.0015 17.7 0.2 1.8 1 1 0 1 1 1 1 Hus1-like protein TIM PF00121.18 EEB09018.1 - 8.3e-87 290.6 1.1 9.6e-87 290.4 1.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Orexin_rec2 PF03827.13 EEB09019.2 - 0.56 10.3 4.4 16 5.6 0.6 3.0 2 0 0 2 2 2 0 Orexin receptor type 2 InvH PF04741.12 EEB09020.1 - 0.12 12.3 1.7 0.21 11.5 0.2 2.2 1 1 0 2 2 2 0 InvH outer membrane lipoprotein DUF2462 PF09495.10 EEB09021.1 - 1.5e-18 67.3 12.7 1.9e-18 67.0 12.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) EMP24_GP25L PF01105.24 EEB09022.1 - 4.3e-45 153.9 0.6 4.9e-45 153.7 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DotU PF09850.9 EEB09022.1 - 0.00033 20.4 0.1 0.0006 19.6 0.1 1.4 1 0 0 1 1 1 1 Type VI secretion system protein DotU PAC4 PF16093.5 EEB09023.2 - 1.4e-14 54.0 0.0 1.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 PIN_4 PF13638.6 EEB09024.2 - 4.8e-32 111.0 0.0 8.4e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 EEB09024.2 - 0.022 15.1 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 PIN like domain XLF PF09302.11 EEB09025.1 - 1.2e-14 54.8 0.2 1.5e-14 54.6 0.2 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component SH3_1 PF00018.28 EEB09026.1 - 2.5e-09 36.6 0.9 3.8e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEB09026.1 - 1.1e-08 34.8 0.7 2.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEB09026.1 - 3.1e-06 26.7 0.0 5.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CGI-121 PF08617.10 EEB09027.1 - 4.3e-43 147.2 0.3 5.2e-43 147.0 0.3 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 THOC7 PF05615.13 EEB09028.1 - 4.5e-18 65.8 14.6 4.5e-18 65.8 14.6 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 DUF848 PF05852.11 EEB09028.1 - 0.0028 17.8 2.9 0.0028 17.8 2.9 2.2 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) Jnk-SapK_ap_N PF09744.9 EEB09028.1 - 0.0057 16.9 22.6 0.035 14.3 14.6 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 FapA PF03961.13 EEB09028.1 - 0.0092 14.6 9.6 0.012 14.3 9.6 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A HNOBA PF07701.14 EEB09028.1 - 0.01 15.3 7.3 0.012 15.0 1.8 2.2 2 0 0 2 2 2 1 Heme NO binding associated Phage_GPA PF05840.13 EEB09028.1 - 0.011 14.9 4.3 0.015 14.4 4.3 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) TORC_N PF12884.7 EEB09028.1 - 0.02 15.7 6.3 2.2 9.1 2.6 2.6 2 1 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Prominin PF05478.11 EEB09028.1 - 0.039 11.9 9.3 0.06 11.3 9.3 1.2 1 0 0 1 1 1 0 Prominin PSII_Pbs27 PF13326.6 EEB09028.1 - 0.042 14.2 3.8 0.084 13.2 3.8 1.6 1 1 0 1 1 1 0 Photosystem II Pbs27 STATa_Ig PF18214.1 EEB09028.1 - 0.043 13.8 0.6 0.081 12.9 0.1 1.7 1 1 1 2 2 2 0 STATa Immunoglobulin-like domain PRANC PF09372.10 EEB09028.1 - 0.047 14.0 2.1 0.32 11.3 0.5 2.5 1 1 1 2 2 2 0 PRANC domain AAA_13 PF13166.6 EEB09028.1 - 0.047 12.3 16.5 0.12 11.0 16.5 1.6 1 1 0 1 1 1 0 AAA domain KxDL PF10241.9 EEB09028.1 - 0.049 13.9 8.0 1.4 9.2 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein CASP_C PF08172.12 EEB09028.1 - 0.05 12.9 10.3 0.73 9.1 1.3 2.2 2 0 0 2 2 2 0 CASP C terminal Striatin PF08232.12 EEB09028.1 - 0.057 14.0 15.2 0.073 13.7 15.2 1.2 1 0 0 1 1 1 0 Striatin family DUF4238 PF14022.6 EEB09028.1 - 0.084 12.4 7.8 0.097 12.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF4795 PF16043.5 EEB09028.1 - 0.1 12.2 14.8 0.099 12.2 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 EEB09028.1 - 0.13 11.6 7.7 0.17 11.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CAMP_factor PF07373.11 EEB09028.1 - 0.18 11.4 8.0 0.047 13.3 1.3 2.1 1 1 1 2 2 2 0 CAMP factor (Cfa) Mt_ATP-synt_D PF05873.12 EEB09028.1 - 0.27 11.1 14.6 0.28 11.0 1.8 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF745 PF05335.13 EEB09028.1 - 0.31 10.7 9.5 0.47 10.2 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) GrpE PF01025.19 EEB09028.1 - 0.32 10.6 20.3 0.064 12.9 2.6 2.5 1 1 1 2 2 2 0 GrpE V_ATPase_I PF01496.19 EEB09028.1 - 0.34 8.8 10.4 0.43 8.4 10.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.17 EEB09028.1 - 0.47 10.5 6.2 0.62 10.1 6.2 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Sec66 PF09802.9 EEB09028.1 - 0.53 9.8 10.9 0.31 10.6 4.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 I_LWEQ PF01608.17 EEB09028.1 - 0.56 10.4 10.8 0.22 11.8 8.6 1.4 2 0 0 2 2 1 0 I/LWEQ domain Exonuc_VII_L PF02601.15 EEB09028.1 - 0.88 9.1 7.8 1.1 8.8 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 EEB09028.1 - 0.89 9.5 14.0 2.6 8.0 1.6 2.6 2 1 0 2 2 2 0 Prefoldin subunit Histone_HNS PF00816.21 EEB09028.1 - 0.96 10.3 8.8 10 7.0 0.3 2.5 2 0 0 2 2 2 0 H-NS histone family Lebercilin PF15619.6 EEB09028.1 - 0.97 9.1 20.8 0.96 9.1 18.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TBCC_N PF16752.5 EEB09028.1 - 1 9.8 16.1 0.49 10.9 5.9 2.7 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Goodbye PF17109.5 EEB09028.1 - 1.1 9.8 7.4 6.6 7.2 0.5 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain Sulfatase_C PF14707.6 EEB09028.1 - 1.2 9.9 7.0 12 6.7 0.9 2.9 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF948 PF06103.11 EEB09028.1 - 1.2 9.4 7.0 11 6.3 0.7 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EEB09028.1 - 1.3 9.6 15.9 2.3 8.8 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 EEB09028.1 - 1.5 9.3 24.2 0.81 10.2 12.2 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EEB09028.1 - 1.6 7.5 22.5 1.2 7.9 2.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 EEB09028.1 - 2.1 8.4 22.9 1.7 8.7 7.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 EEB09028.1 - 2.7 8.1 17.6 4.1 7.4 6.8 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 EEB09028.1 - 2.8 8.0 10.5 6.2 6.9 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EEB09028.1 - 2.9 6.7 11.9 3.4 6.5 11.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MRPL52 PF18699.1 EEB09028.1 - 3 8.1 16.9 0.26 11.5 3.0 2.6 1 1 2 3 3 3 0 Mitoribosomal protein mL52 Syntaxin_2 PF14523.6 EEB09028.1 - 3 8.3 16.0 0.98 9.8 9.9 2.6 2 1 1 3 3 2 0 Syntaxin-like protein G6PD_N PF00479.22 EEB09028.1 - 3.4 8.3 8.3 14 6.2 7.6 2.2 1 1 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Cupin_8 PF13621.6 EEB09028.1 - 3.9 7.1 6.8 6.5 6.4 6.8 1.5 1 1 0 1 1 1 0 Cupin-like domain DUF4298 PF14131.6 EEB09028.1 - 4.6 7.3 12.6 9.9 6.2 0.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) OmpH PF03938.14 EEB09028.1 - 5.6 7.3 20.1 28 5.0 20.2 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2508 PF10704.9 EEB09028.1 - 6.2 7.1 17.8 12 6.1 1.9 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2951 PF11166.8 EEB09028.1 - 6.6 7.0 14.5 8 6.8 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) TMPIT PF07851.13 EEB09028.1 - 6.7 5.9 14.8 5.5 6.1 12.5 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF4355 PF14265.6 EEB09028.1 - 7.8 6.8 21.0 34 4.7 19.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) AAA PF00004.29 EEB09029.2 - 6.5e-38 130.1 0.0 1.2e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEB09029.2 - 2.3e-07 31.2 1.8 0.0011 19.2 0.1 3.4 1 1 2 3 3 3 2 AAA domain AAA_16 PF13191.6 EEB09029.2 - 1.2e-06 29.0 3.9 0.00053 20.4 0.0 2.8 2 1 1 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 EEB09029.2 - 2e-06 27.8 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEB09029.2 - 4.7e-06 26.4 0.0 9.6e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEB09029.2 - 1.4e-05 25.1 0.7 0.00021 21.3 0.7 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EEB09029.2 - 7.1e-05 22.3 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_33 PF13671.6 EEB09029.2 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 EEB09029.2 - 0.00017 21.3 0.2 0.00078 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_24 PF13479.6 EEB09029.2 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EEB09029.2 - 0.00027 20.9 0.2 0.0013 18.7 0.1 2.0 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EEB09029.2 - 0.0003 20.4 1.5 0.12 11.9 0.1 3.1 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EEB09029.2 - 0.00044 20.0 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB09029.2 - 0.00047 19.6 1.8 0.00083 18.8 0.2 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EEB09029.2 - 0.00062 19.9 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 EEB09029.2 - 0.00068 20.2 0.0 0.0012 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB09029.2 - 0.00075 19.9 0.0 0.0017 18.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 EEB09029.2 - 0.0024 18.0 0.0 0.0063 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 EEB09029.2 - 0.0034 17.1 0.0 0.013 15.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 EEB09029.2 - 0.0036 17.6 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EEB09029.2 - 0.0052 16.8 0.0 0.05 13.6 0.0 2.4 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EEB09029.2 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.12 EEB09029.2 - 0.0081 16.1 1.3 0.033 14.1 0.3 2.3 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 EEB09029.2 - 0.0091 15.9 0.1 0.2 11.6 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 EEB09029.2 - 0.0096 15.3 0.1 1.6 8.0 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_17 PF13207.6 EEB09029.2 - 0.02 15.3 0.1 0.051 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEB09029.2 - 0.024 13.9 0.1 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_3 PF07726.11 EEB09029.2 - 0.026 14.4 0.0 0.064 13.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 EEB09029.2 - 0.033 14.3 0.1 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.13 EEB09029.2 - 0.037 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EEB09029.2 - 0.039 13.2 0.1 0.089 12.0 0.0 1.6 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 EEB09029.2 - 0.042 13.4 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EEB09029.2 - 0.054 14.0 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 EEB09029.2 - 0.058 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.11 EEB09029.2 - 0.079 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain Viral_helicase1 PF01443.18 EEB09029.2 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Guanylate_kin PF00625.21 EEB09029.2 - 0.11 12.1 0.1 1.3 8.7 0.0 2.5 2 1 1 3 3 3 0 Guanylate kinase CPT PF07931.12 EEB09029.2 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.25 EEB09029.2 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_S17e PF00833.18 EEB09030.2 - 3e-61 204.7 0.9 3.5e-61 204.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 IpaB_EvcA PF03278.13 EEB09030.2 - 0.091 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 IpaB/EvcA family Myb_DNA-binding PF00249.31 EEB09031.1 - 2.2e-11 43.7 0.0 4.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EEB09031.1 - 2.4e-11 43.2 6.5 4.1e-11 42.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EEB09031.1 - 4.3e-09 36.6 0.0 1.4e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Baculo_IE-1 PF05290.11 EEB09031.1 - 0.03 14.3 1.9 0.071 13.1 1.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.16 EEB09031.1 - 0.046 14.0 6.9 0.1 12.9 6.9 1.6 1 0 0 1 1 1 0 C1 domain DUF3427 PF11907.8 EEB09031.1 - 0.085 12.1 0.6 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Fungal_KA1 PF16797.5 EEB09031.1 - 0.088 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Fungal kinase associated-1 domain Pkinase PF00069.25 EEB09032.1 - 1e-66 225.0 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09032.1 - 1.7e-29 102.9 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEB09032.1 - 2.2e-09 37.9 1.6 6.1e-09 36.5 1.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EEB09032.1 - 1.9e-08 33.7 0.1 1.9e-08 33.7 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain C2 PF00168.30 EEB09032.1 - 1.5e-06 28.5 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EEB09032.1 - 0.0025 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EEB09032.1 - 0.038 13.6 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB09032.1 - 0.23 11.4 0.1 0.41 10.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEB09032.1 - 0.25 10.7 0.2 0.41 10.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L50 PF10501.9 EEB09033.1 - 3e-05 24.1 0.0 5.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal subunit 39S zf-Tim10_DDP PF02953.15 EEB09034.1 - 5.9e-19 67.5 2.7 7.6e-19 67.1 2.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 EEB09034.1 - 0.0042 17.3 0.1 0.34 11.2 0.1 2.0 1 1 1 2 2 2 2 Phasin protein DUF3069 PF11269.8 EEB09034.1 - 0.089 13.0 0.3 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3069) DUF4105 PF13387.6 EEB09034.1 - 0.092 12.4 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) MCM PF00493.23 EEB09036.1 - 2.9e-99 330.7 0.0 4e-99 330.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEB09036.1 - 1.3e-38 131.7 0.6 2.4e-38 130.8 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEB09036.1 - 4.6e-28 97.5 3.7 1e-27 96.4 3.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEB09036.1 - 1.2e-16 61.2 1.5 2.3e-16 60.2 0.1 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEB09036.1 - 4.8e-06 26.1 0.0 0.0004 19.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEB09036.1 - 1.1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEB09036.1 - 8.6e-05 22.4 0.0 0.0014 18.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEB09036.1 - 0.012 15.3 0.3 3.1 7.5 0.0 3.9 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_16 PF13191.6 EEB09036.1 - 0.49 10.8 3.1 2.3 8.5 0.0 3.0 3 1 1 4 4 4 0 AAA ATPase domain Proteasom_Rpn13 PF04683.13 EEB09037.1 - 3.8e-29 101.1 0.0 8.1e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EEB09037.1 - 0.0045 17.1 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 UCH-binding domain SNF5 PF04855.12 EEB09039.2 - 4.5e-52 177.2 0.1 2.2e-26 93.1 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EEB09039.2 - 5.3e-11 41.9 5.3 5.3e-11 41.9 5.3 2.9 3 0 0 3 3 3 1 GATA zinc finger LUC7 PF03194.15 EEB09040.1 - 4e-73 246.2 8.0 4.9e-73 245.9 8.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Swi5 PF07061.11 EEB09040.1 - 1.5 9.0 7.1 2.4 8.3 3.0 2.9 1 1 1 2 2 2 0 Swi5 Occludin_ELL PF07303.13 EEB09040.1 - 5.3 7.8 8.6 71 4.2 7.9 2.8 1 1 1 2 2 2 0 Occludin homology domain UCH PF00443.29 EEB09041.1 - 3e-71 239.9 1.1 4.3e-71 239.4 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEB09041.1 - 1.3e-15 57.8 6.3 2.1e-07 30.9 0.7 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EEB09041.1 - 4.9e-11 43.1 0.0 1.9e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 DUSP domain L31 PF09784.9 EEB09042.1 - 4.7e-42 142.6 0.3 5.4e-42 142.4 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cyt-b5 PF00173.28 EEB09043.1 - 1.1e-24 86.3 0.1 1.6e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 EEB09043.1 - 0.15 12.1 1.0 0.27 11.3 1.0 1.4 1 0 0 1 1 1 0 YqzH-like protein Tim17 PF02466.19 EEB09044.1 - 1.9e-25 89.4 8.1 2.5e-25 89.0 8.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.24 EEB09045.1 - 3e-19 69.1 0.3 1.3e-18 67.0 0.1 2.0 2 0 0 2 2 2 1 PX domain DUF2009 PF09418.10 EEB09046.2 - 2.4e-193 643.4 0.5 2.8e-193 643.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PXA PF02194.15 EEB09047.1 - 5.1e-33 114.6 4.0 6.1e-33 114.3 0.6 2.5 2 0 0 2 2 2 1 PXA domain RGS PF00615.19 EEB09047.1 - 5e-20 71.9 0.4 1.5e-19 70.4 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.24 EEB09047.1 - 1.3e-19 70.3 1.9 1.1e-18 67.2 0.1 3.1 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.12 EEB09047.1 - 0.00014 22.4 1.4 0.0007 20.2 0.0 2.9 3 0 0 3 3 3 1 Sorting nexin C terminal DsrH PF04077.12 EEB09047.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein ABC_tran_CTD PF16326.5 EEB09047.1 - 0.88 9.9 3.8 56 4.1 2.8 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DIM1 PF02966.16 EEB09048.1 - 7.4e-70 232.9 0.3 8.3e-70 232.7 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EEB09048.1 - 0.0015 18.5 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 EEB09048.1 - 0.059 13.3 0.2 0.084 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) Polyketide_cyc PF03364.20 EEB09049.1 - 2.1e-24 86.2 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EEB09049.1 - 0.00012 22.4 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_22 PF03901.17 EEB09050.1 - 7.5e-99 331.8 33.0 8.7e-99 331.6 33.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EEB09050.1 - 2.6e-06 27.8 12.0 2.6e-06 27.8 12.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 EEB09051.1 - 3.6e-63 208.0 23.6 4.1e-08 33.8 0.3 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EEB09051.1 - 7.9e-50 168.4 1.0 1.6e-49 167.4 1.0 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EEB09051.1 - 4.4e-29 100.6 8.8 0.00065 20.0 0.0 8.9 4 2 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB09051.1 - 9.8e-09 34.6 2.9 0.0064 15.5 0.0 5.1 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEB09051.1 - 2.3e-08 33.1 4.7 0.29 9.7 0.0 5.9 3 3 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEB09051.1 - 4.4e-06 25.7 0.9 2.5 6.8 0.0 6.0 4 2 1 6 6 6 2 Nup133 N terminal like WD40_like PF17005.5 EEB09051.1 - 7.4e-06 25.5 0.1 0.039 13.3 0.0 4.6 3 1 1 5 5 5 1 WD40-like domain VID27 PF08553.10 EEB09051.1 - 0.00028 20.1 0.4 0.082 11.9 0.0 3.1 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain Nbas_N PF15492.6 EEB09051.1 - 0.025 13.9 0.0 27 4.0 0.0 3.8 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 EEB09051.1 - 0.03 13.1 0.1 14 4.3 0.0 3.3 4 0 0 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PD40 PF07676.12 EEB09051.1 - 0.16 11.9 0.0 4.8 7.2 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Frag1 PF10277.9 EEB09052.1 - 1.7e-31 109.5 19.4 2e-31 109.2 19.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAIN PF15301.6 EEB09052.1 - 0.11 11.7 2.3 0.15 11.3 2.3 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family DUF5316 PF17247.2 EEB09052.1 - 0.12 12.4 2.3 1.5 8.9 0.1 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5316) GWT1 PF06423.12 EEB09052.1 - 0.77 9.9 7.0 1.1 9.3 5.4 2.1 2 1 0 2 2 2 0 GWT1 Eisosome1 PF12757.7 EEB09053.2 - 3.7e-20 72.4 10.1 3.7e-20 72.4 10.1 3.3 3 1 0 3 3 3 1 Eisosome protein 1 DnaJ PF00226.31 EEB09054.1 - 7e-22 77.3 0.3 4.3e-21 74.8 0.8 1.8 2 0 0 2 2 2 1 DnaJ domain DUF456 PF04306.13 EEB09054.1 - 0.00038 20.7 0.1 0.00058 20.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) RPT PF13446.6 EEB09054.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF1269 PF06897.12 EEB09054.1 - 0.072 13.4 1.3 0.12 12.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 EEB09054.1 - 5.6 6.9 12.3 0.78 9.7 0.3 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EEB09054.1 - 5.6 7.0 12.5 0.34 10.9 3.8 2.2 2 0 0 2 2 2 0 Glycine zipper Proteasome PF00227.26 EEB09055.1 - 2.9e-43 147.6 0.0 3.3e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 EEB09055.1 - 0.0038 17.3 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 2 Phage late-transcription coactivator DEAD PF00270.29 EEB09056.1 - 3.1e-50 170.4 0.0 1.7e-48 164.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09056.1 - 1.2e-29 102.9 0.1 3.1e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09056.1 - 0.00059 19.9 0.1 0.0024 17.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EEB09056.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 EEB09056.1 - 0.013 16.0 0.7 0.06 13.9 0.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Peripla_BP_1 PF00532.21 EEB09056.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family HEAT_PBS PF03130.16 EEB09056.1 - 0.1 13.3 0.2 0.53 11.1 0.0 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat CTP_transf_1 PF01148.20 EEB09057.1 - 0.00029 20.7 9.9 0.00029 20.7 9.9 2.4 1 1 1 3 3 3 1 Cytidylyltransferase family MatE PF01554.18 EEB09057.1 - 0.00033 20.3 0.9 0.00033 20.3 0.9 2.4 2 0 0 2 2 2 1 MatE Pkinase PF00069.25 EEB09058.1 - 5.9e-57 193.0 0.0 1.1e-56 192.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 EEB09058.1 - 6.2e-47 160.1 1.0 9.2e-47 159.5 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 EEB09058.1 - 7.1e-41 140.2 0.0 9.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB09058.1 - 0.037 12.8 0.0 0.067 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EEB09058.1 - 0.093 12.0 0.0 12 5.2 0.0 2.6 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 EEB09058.1 - 0.15 11.9 0.0 0.57 10.1 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Thg1 PF04446.12 EEB09059.1 - 1.4e-51 173.7 0.1 2.6e-51 172.9 0.1 1.5 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EEB09059.1 - 2.7e-44 150.2 0.3 5.8e-44 149.2 0.3 1.6 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.32 EEB09060.1 - 1.7e-07 31.8 0.8 0.14 13.1 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40_like PF17005.5 EEB09060.1 - 0.013 14.9 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain TAP42 PF04177.12 EEB09061.1 - 9.9e-78 261.5 15.9 1.3e-77 261.1 15.9 1.1 1 0 0 1 1 1 1 TAP42-like family UCH PF00443.29 EEB09061.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_5 PF08323.11 EEB09062.1 - 9.2e-14 51.7 0.2 1.8e-13 50.8 0.2 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EEB09062.1 - 5.5e-08 32.5 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEB09062.1 - 7.4e-06 26.4 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB09062.1 - 0.0035 17.3 0.2 0.0077 16.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EEB09062.1 - 0.015 15.7 0.3 4.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain baeRF_family6 PF18848.1 EEB09062.1 - 0.027 14.9 0.9 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 DUF3395 PF11875.8 EEB09063.1 - 7.5e-23 81.2 5.7 9.8e-22 77.5 5.7 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EEB09063.1 - 2.3e-18 66.1 2.9 5.1e-18 65.0 2.9 1.6 1 0 0 1 1 1 1 DnaJ domain Hydrolase_6 PF13344.6 EEB09063.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.24 EEB09064.1 - 2.3e-50 172.1 1.4 3.5e-50 171.5 1.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EEB09064.1 - 1.3e-09 38.2 0.3 1.3e-09 38.2 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 EEB09064.1 - 0.083 12.0 0.3 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Complex1_LYR PF05347.15 EEB09066.2 - 3.9e-10 39.6 0.8 7.6e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Sugar_tr PF00083.24 EEB09067.1 - 1.8e-40 139.1 22.3 2e-24 86.3 1.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEB09067.1 - 2.1e-19 69.7 26.3 1.7e-11 43.7 8.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEB09067.1 - 0.0019 17.6 0.7 0.0019 17.6 0.7 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PAP_assoc PF03828.19 EEB09067.1 - 0.72 10.1 4.5 0.16 12.2 0.6 2.0 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF89 PF01937.19 EEB09068.1 - 9.2e-120 399.8 0.0 1e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF883 PF05957.13 EEB09069.1 - 0.064 13.9 5.4 0.085 13.5 3.6 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EEB09069.1 - 0.51 10.9 9.5 0.33 11.5 1.8 2.2 1 1 1 2 2 2 0 YtxH-like protein ATP-synt_B PF00430.18 EEB09069.1 - 0.8 9.8 8.0 1.2 9.2 8.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) LEA_4 PF02987.16 EEB09069.1 - 1.6 8.9 8.3 1.7 8.8 1.6 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein MRP-L20 PF12824.7 EEB09070.2 - 5e-17 62.6 0.1 6.6e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EEB09070.2 - 0.0018 18.4 0.3 0.0037 17.3 0.3 1.4 1 1 1 2 2 2 1 Neugrin HTH_32 PF13565.6 EEB09070.2 - 0.0075 16.9 2.1 0.012 16.3 1.5 1.6 1 1 0 1 1 1 1 Homeodomain-like domain HDV_ag PF01517.18 EEB09070.2 - 0.081 12.7 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Ten1 PF12658.7 EEB09071.1 - 1.4e-17 63.7 0.0 1.7e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Chitin_synth_1 PF01644.17 EEB09071.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase Ctr PF04145.15 EEB09072.1 - 4e-31 108.6 4.1 4e-31 108.6 4.1 1.7 2 0 0 2 2 2 1 Ctr copper transporter family FA_desaturase PF00487.24 EEB09072.1 - 0.015 15.1 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Macoilin PF09726.9 EEB09072.1 - 0.65 8.5 3.2 0.76 8.3 3.2 1.2 1 0 0 1 1 1 0 Macoilin family Nucleoporin_FG2 PF15967.5 EEB09072.1 - 2.3 6.7 15.7 3.3 6.1 15.7 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Lung_7-TM_R PF06814.13 EEB09073.1 - 0.00013 21.3 4.2 0.00026 20.3 4.2 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor RWD PF05773.22 EEB09074.1 - 1.3e-17 64.1 2.0 2.3e-17 63.4 2.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EEB09074.1 - 1.9e-06 28.3 7.8 1.9e-06 28.3 7.8 2.3 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 DUF445 PF04286.12 EEB09074.1 - 0.0012 18.8 4.2 0.0014 18.6 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1003 PF06210.11 EEB09074.1 - 0.29 11.2 0.2 0.29 11.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) GATA PF00320.27 EEB09075.2 - 5.7e-28 96.2 19.4 3.4e-14 52.1 1.9 3.1 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EEB09075.2 - 0.0001 21.7 2.9 0.088 12.3 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 EEB09075.2 - 0.09 12.9 2.4 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) NMD3 PF04981.13 EEB09075.2 - 0.22 11.0 3.0 9.2 5.7 0.2 2.1 2 0 0 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.17 EEB09075.2 - 0.6 10.0 6.4 1.9 8.4 1.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 EEB09075.2 - 0.71 10.0 3.5 1.7 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 EEB09075.2 - 0.88 9.3 4.9 11 5.9 0.4 2.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 EEB09075.2 - 1 9.4 9.6 7.5 6.6 2.9 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 EEB09075.2 - 3.6 7.7 9.3 60 3.8 9.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 EEB09075.2 - 4 7.7 7.6 18 5.6 0.9 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 EEB09075.2 - 5.5 7.0 8.2 11 6.1 1.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain TFIIA PF03153.13 EEB09075.2 - 6.9 6.5 16.6 0.44 10.5 9.2 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAN_2 PF08276.11 EEB09076.1 - 0.021 14.9 0.2 0.12 12.5 0.2 2.3 1 0 0 1 1 1 0 PAN-like domain Ipi1_N PF12333.8 EEB09077.2 - 2.9e-23 82.4 0.5 1.3e-22 80.3 0.5 2.2 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation DUF3456 PF11938.8 EEB09078.1 - 0.11 13.0 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP RIG-I_C PF18119.1 EEB09079.1 - 0.012 15.6 5.9 0.029 14.4 5.8 2.0 1 1 0 1 1 1 0 RIG-I receptor C-terminal domain ECM11 PF15463.6 EEB09079.1 - 0.1 13.2 7.4 0.16 12.6 0.0 2.9 3 0 0 3 3 3 0 Extracellular mutant protein 11 YlzJ PF14035.6 EEB09079.1 - 0.11 12.7 0.6 1 9.6 0.1 2.4 2 0 0 2 2 2 0 YlzJ-like protein SpecificRecomb PF10136.9 EEB09079.1 - 1.2 7.4 3.8 1.6 6.9 3.9 1.3 1 1 0 1 1 1 0 Site-specific recombinase BAG PF02179.16 EEB09079.1 - 3.9 8.0 8.6 3.5 8.1 3.8 3.2 2 1 0 2 2 2 0 BAG domain FTA4 PF13093.6 EEB09080.1 - 5.9e-22 78.5 15.8 7.3e-22 78.2 15.8 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1759 PF03564.15 EEB09080.1 - 0.57 10.1 5.2 0.8 9.6 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Ribosomal_S19 PF00203.21 EEB09081.1 - 6.9e-34 115.6 0.3 1.2e-33 114.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 SPT2 PF08243.11 EEB09082.1 - 3e-23 82.4 9.6 3e-23 82.4 9.6 3.2 3 1 0 3 3 3 1 SPT2 chromatin protein E1-E2_ATPase PF00122.20 EEB09083.2 - 8e-45 152.6 7.0 3.4e-44 150.5 2.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EEB09083.2 - 1.7e-18 67.7 0.2 9.6e-18 65.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEB09083.2 - 1.3e-09 37.6 0.0 3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEB09083.2 - 0.0034 17.1 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEB09083.2 - 0.0083 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2613 PF11021.8 EEB09083.2 - 5.1 7.3 7.4 8.4 6.6 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Spc7 PF08317.11 EEB09084.1 - 4.4e-64 216.3 8.0 1.1e-63 215.0 8.0 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EEB09084.1 - 2.3e-13 50.0 0.3 6.6e-13 48.5 0.3 1.9 1 0 0 1 1 1 1 Spc7_C2 Cation_efflux PF01545.21 EEB09085.1 - 5e-45 153.7 5.4 6.2e-45 153.4 5.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EEB09085.1 - 0.031 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Osw5 PF17062.5 EEB09085.1 - 0.033 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Outer spore wall 5 RNA_pol_Rpb6 PF01192.22 EEB09086.1 - 2e-17 62.8 0.1 3.1e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Metallophos PF00149.28 EEB09087.1 - 9.1e-21 75.3 0.0 1.4e-20 74.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEB09087.1 - 5.6e-07 29.9 0.0 6.9e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TAL_FSA PF00923.19 EEB09088.1 - 3e-96 322.2 1.0 3.4e-96 322.0 1.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase EAL PF00563.20 EEB09088.1 - 0.011 15.3 0.0 2.8 7.4 0.0 2.2 2 1 0 2 2 2 0 EAL domain HAD_2 PF13419.6 EEB09089.1 - 9.4e-21 74.7 0.0 1.2e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB09089.1 - 4.7e-11 43.4 0.0 4.4e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEB09089.1 - 0.018 15.2 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 EEB09089.1 - 0.073 12.9 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Radical_SAM PF04055.21 EEB09090.1 - 3.5e-26 92.6 0.1 1.5e-25 90.5 0.1 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EEB09090.1 - 3.5e-25 88.1 0.0 8.4e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EEB09090.1 - 2.4e-14 53.8 0.0 4.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EEB09090.1 - 0.03 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain WD40 PF00400.32 EEB09091.1 - 6.2e-08 33.2 3.9 0.12 13.3 0.1 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09091.1 - 6.4e-08 32.8 0.0 0.11 12.8 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EEB09091.1 - 0.25 9.3 0.0 1.7 6.5 0.0 2.0 1 1 0 2 2 2 0 IKI3 family Pkinase PF00069.25 EEB09092.2 - 3.2e-46 157.9 0.0 6.6e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09092.2 - 6.7e-19 68.2 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB09092.2 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEB09092.2 - 0.02 14.5 0.1 3.4 7.2 0.0 2.7 3 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 FAD_binding_1 PF00667.20 EEB09094.1 - 1.8e-70 237.0 0.1 2.5e-70 236.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EEB09094.1 - 1e-34 119.8 1.4 1.4e-34 119.4 0.5 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EEB09094.1 - 1.4e-19 70.7 0.1 4.6e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain ART-PolyVal PF18760.1 EEB09094.1 - 0.12 13.5 0.3 0.57 11.2 0.1 2.1 2 0 0 2 2 2 0 ADP-Ribosyltransferase in polyvalent proteins RRM_1 PF00076.22 EEB09095.1 - 6.6e-25 86.7 0.0 5.4e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1A PF12253.8 EEB09096.1 - 8.4e-19 67.5 9.0 8.4e-19 67.5 9.0 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A TFIIA PF03153.13 EEB09096.1 - 0.00064 19.8 16.9 0.0012 18.9 16.9 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CUE PF02845.16 EEB09096.1 - 0.0084 15.8 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain SOBP PF15279.6 EEB09096.1 - 1.3 9.6 13.6 0.39 11.3 10.0 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein DUF3492 PF11997.8 EEB09096.1 - 2.1 8.0 8.8 2.4 7.9 7.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) TAF6_C PF07571.13 EEB09098.1 - 1.4e-33 115.0 0.0 4.1e-33 113.6 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EEB09098.1 - 9.2e-30 102.6 0.1 2e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EEB09098.1 - 0.00072 19.9 0.3 0.0018 18.6 0.3 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEB09098.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT PF02985.22 EEB09098.1 - 0.017 15.3 0.2 6 7.4 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Vps5 PF09325.10 EEB09099.1 - 1.4e-62 211.3 12.5 1.4e-62 211.3 12.5 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EEB09099.1 - 2.9e-22 78.8 0.5 1.4e-21 76.6 0.0 2.3 2 1 0 2 2 2 1 PX domain FGGY_N PF00370.21 EEB09100.1 - 3.5e-25 89.0 0.0 1.4e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EEB09100.1 - 2e-23 83.2 0.0 3.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ABC2_membrane PF01061.24 EEB09101.1 - 5.9e-80 267.6 52.6 2.1e-42 145.0 20.2 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EEB09101.1 - 2.3e-33 113.9 13.5 1.7e-29 101.6 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 EEB09101.1 - 7.7e-32 110.7 0.0 2.6e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 EEB09101.1 - 1.2e-10 41.9 0.3 3.3e-10 40.4 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EEB09101.1 - 6.3e-07 29.5 0.0 4.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EEB09101.1 - 5.5e-05 23.6 0.0 0.021 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EEB09101.1 - 0.00044 19.9 0.0 0.0076 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEB09101.1 - 0.00064 19.4 0.1 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EEB09101.1 - 0.0023 18.0 0.0 0.49 10.5 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EEB09101.1 - 0.0052 16.7 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EEB09101.1 - 0.011 15.4 0.1 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 EEB09101.1 - 0.015 14.4 58.9 0.038 13.1 27.4 3.9 2 2 1 3 3 3 0 ABC-2 family transporter protein RNA_helicase PF00910.22 EEB09101.1 - 0.018 15.4 0.0 0.31 11.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EEB09101.1 - 0.02 15.2 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EEB09101.1 - 0.025 14.6 0.1 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EEB09101.1 - 0.051 12.8 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EEB09101.1 - 0.057 13.6 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEB09101.1 - 0.06 13.8 0.0 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EEB09101.1 - 0.076 12.8 0.2 5.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 EEB09101.1 - 0.077 12.8 0.0 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EEB09101.1 - 0.078 12.6 1.1 0.14 11.8 0.3 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EEB09101.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_ATPase PF09818.9 EEB09101.1 - 0.19 10.5 0.2 0.37 9.5 0.2 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Pkinase PF00069.25 EEB09102.1 - 5.9e-52 176.6 0.0 7.9e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09102.1 - 1.3e-34 119.7 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EEB09102.1 - 0.21 10.6 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S18 PF01084.20 EEB09103.2 - 3.7e-20 71.9 0.0 8.2e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Phos_pyr_kin PF08543.12 EEB09104.2 - 2.5e-63 213.7 0.0 3.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 EEB09104.2 - 6.8e-05 22.4 0.1 0.00036 20.0 0.0 2.0 3 0 0 3 3 3 1 Hydroxyethylthiazole kinase family eRF1_1 PF03463.15 EEB09105.1 - 5.8e-47 158.9 0.3 1e-46 158.1 0.1 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 EEB09105.1 - 1.1e-29 103.5 0.1 1.9e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EEB09105.1 - 3e-23 82.5 0.0 6.3e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 HgmA PF04209.13 EEB09105.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Ran_BP1 PF00638.18 EEB09106.1 - 1e-20 74.2 0.2 2.5e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 EEB09106.1 - 4.2e-14 52.9 1.9 4.2e-14 52.9 1.9 3.8 3 0 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) tRNA-synt_1 PF00133.22 EEB09107.1 - 3.1e-145 484.8 0.0 4.7e-145 484.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEB09107.1 - 2.2e-19 69.5 0.2 3.7e-13 49.0 0.0 4.0 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEB09107.1 - 9.3e-17 61.4 0.9 2.1e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EEB09107.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 EEB09107.1 - 6.8 6.7 6.8 21 5.1 6.8 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS NCBP3 PF10309.9 EEB09108.1 - 8.1e-06 25.6 0.1 1.2e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 PB1 PF00564.24 EEB09108.1 - 0.024 14.6 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 PB1 domain WD40 PF00400.32 EEB09109.1 - 3.8e-20 71.8 13.7 0.0013 19.5 0.8 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09109.1 - 1.3e-18 67.0 0.0 0.0025 18.1 0.1 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB09109.1 - 3.2e-11 43.5 0.7 9.4e-05 22.4 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EEB09109.1 - 5.1e-05 22.7 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain IKI3 PF04762.12 EEB09109.1 - 0.00011 20.4 0.6 0.086 10.8 0.0 2.8 3 0 0 3 3 3 2 IKI3 family Coatomer_WDAD PF04053.14 EEB09109.1 - 0.00021 20.5 0.0 0.019 14.0 0.0 2.3 2 1 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 EEB09109.1 - 0.0041 15.7 0.0 0.8 8.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Pkinase PF00069.25 EEB09110.1 - 5.1e-75 252.2 0.2 6.4e-75 251.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09110.1 - 1.3e-39 136.1 0.1 1.8e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEB09110.1 - 4.7e-15 55.7 0.4 1e-14 54.6 0.4 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EEB09110.1 - 7.2e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EEB09110.1 - 3.9e-06 26.6 0.2 1.1e-05 25.2 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EEB09110.1 - 5e-06 25.6 0.1 7.8e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EEB09110.1 - 5.2e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EEB09110.1 - 0.0028 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEB09110.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEB09110.1 - 0.057 13.3 0.0 0.6 10.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CoaE PF01121.20 EEB09111.1 - 3.1e-59 199.7 0.0 3.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EEB09111.1 - 1.1e-05 26.0 0.2 6.8e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EEB09111.1 - 0.0054 16.6 0.1 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.6 EEB09111.1 - 0.011 15.8 0.0 0.04 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 EEB09111.1 - 0.027 14.6 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.12 EEB09111.1 - 0.037 13.3 0.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EEB09111.1 - 0.082 13.3 0.1 0.27 11.6 0.0 1.9 1 1 2 3 3 3 0 AAA domain PRK PF00485.18 EEB09111.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 EEB09111.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Npa1 PF11707.8 EEB09112.2 - 5.8e-58 196.9 4.1 5.8e-58 196.9 4.1 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EEB09112.2 - 1e-06 28.5 1.1 4.8e-06 26.3 0.1 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 ERK-JNK_inhib PF15002.6 EEB09112.2 - 0.15 11.7 1.4 0.39 10.4 0.2 2.1 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor UMP1 PF05348.11 EEB09113.1 - 7.9e-25 87.4 0.0 9e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PNISR PF15996.5 EEB09114.1 - 0.004 17.5 1.7 0.008 16.5 1.7 1.5 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR DDHD PF02862.17 EEB09115.1 - 2e-24 87.0 0.5 7e-23 82.0 0.5 2.3 1 1 0 1 1 1 1 DDHD domain Hydrolase_4 PF12146.8 EEB09115.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 cobW PF02492.19 EEB09115.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain XAP5 PF04921.14 EEB09116.1 - 4.5e-43 147.9 6.1 5.9e-43 147.5 6.1 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator 40S_S4_C PF16121.5 EEB09116.1 - 0.019 14.6 0.1 0.09 12.4 0.1 2.2 2 0 0 2 2 2 0 40S ribosomal protein S4 C-terminus Rab5ip PF07019.12 EEB09117.1 - 5.2e-23 81.4 11.2 6.1e-23 81.2 11.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MFS_1 PF07690.16 EEB09118.1 - 1.4e-05 24.2 25.6 0.00012 21.2 18.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 EEB09119.1 - 2.4e-105 352.9 30.4 2.9e-105 352.6 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB09119.1 - 5.2e-32 111.2 33.1 6.8e-32 110.8 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 EEB09119.1 - 0.67 9.8 6.4 15 5.5 1.3 3.3 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TauD PF02668.16 EEB09120.1 - 6.2e-39 134.4 0.9 7.7e-39 134.1 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Asp_Glu_race PF01177.22 EEB09121.1 - 3.1e-09 37.0 0.3 3.8e-09 36.7 0.3 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CSTF_C PF14304.6 EEB09121.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Uricase PF01014.18 EEB09122.1 - 2.2e-64 215.6 5.0 3.2e-34 118.0 1.2 2.0 2 0 0 2 2 2 2 Uricase Transthyretin PF00576.21 EEB09123.1 - 5e-35 120.5 0.0 5.5e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF3244 PF11589.8 EEB09123.1 - 0.041 14.0 0.0 0.089 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) bMG3 PF11974.8 EEB09123.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 1 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Glyco_hydro_32N PF00251.20 EEB09124.1 - 1.2e-72 245.1 8.1 1.9e-71 241.1 6.7 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EEB09124.1 - 1.2e-07 31.9 1.5 2.6e-07 30.7 0.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 EEB09124.1 - 0.13 12.4 1.7 0.67 10.2 0.1 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat WXG100 PF06013.12 EEB09125.1 - 0.0042 17.3 0.9 0.0042 17.3 0.9 2.1 1 1 1 2 2 2 1 Proteins of 100 residues with WXG Latarcin PF10279.9 EEB09125.1 - 0.0069 16.8 0.2 0.012 16.0 0.2 1.5 1 0 0 1 1 1 1 Latarcin precursor SH3BP5 PF05276.14 EEB09125.1 - 0.013 15.3 3.9 0.58 9.9 0.1 2.1 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Tweety PF04906.13 EEB09125.1 - 0.017 13.8 1.0 0.019 13.7 1.0 1.2 1 0 0 1 1 1 0 Tweety DUF4363 PF14276.6 EEB09125.1 - 0.04 14.0 3.4 0.049 13.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) Pex19 PF04614.12 EEB09125.1 - 0.041 13.7 3.9 0.051 13.4 3.9 1.2 1 0 0 1 1 1 0 Pex19 protein family UPF0122 PF04297.14 EEB09125.1 - 0.09 13.0 2.0 0.12 12.7 0.2 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like FliE PF02049.18 EEB09125.1 - 0.11 12.6 7.0 0.51 10.5 0.7 2.6 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE PIN_8 PF18476.1 EEB09125.1 - 0.23 11.3 4.3 0.27 11.1 3.4 1.5 1 1 1 2 2 2 0 PIN like domain ApoLp-III PF07464.11 EEB09125.1 - 0.47 10.5 8.1 0.85 9.7 3.4 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prefoldin PF02996.17 EEB09125.1 - 1.2 9.1 6.0 1.1 9.2 1.2 2.4 2 1 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 EEB09125.1 - 1.5 9.4 5.6 1 9.9 1.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_L23eN PF03939.13 EEB09126.1 - 3.3e-20 72.0 7.2 3.3e-20 72.0 7.2 1.8 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EEB09126.1 - 2.5e-16 59.8 4.4 2.5e-16 59.8 4.4 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 Abhydrolase_1 PF00561.20 EEB09127.1 - 1.4e-44 152.6 0.2 6.1e-44 150.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEB09127.1 - 0.00077 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Proteasome PF00227.26 EEB09128.1 - 9.4e-58 194.8 0.2 1.2e-57 194.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB09128.1 - 2e-12 46.6 0.2 8.6e-12 44.5 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NUDIX PF00293.28 EEB09129.1 - 3.2e-22 79.0 0.0 6e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain ResIII PF04851.15 EEB09129.1 - 0.082 12.9 0.2 0.17 11.8 0.2 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SDA1 PF05285.12 EEB09130.1 - 5.5e-80 269.4 39.7 3.6e-46 158.2 10.6 3.3 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 EEB09130.1 - 7.5e-21 74.2 0.2 2.4e-20 72.6 0.2 2.0 1 0 0 1 1 1 1 NUC130/3NT domain DUF1911 PF08929.10 EEB09130.1 - 0.043 14.6 0.3 0.16 12.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) CLTH PF10607.9 EEB09131.1 - 1.4e-26 93.1 0.0 8.3e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Sec34 PF04136.15 EEB09131.1 - 0.036 13.9 1.1 0.07 13.0 1.1 1.4 1 0 0 1 1 1 0 Sec34-like family GPS2_interact PF15784.5 EEB09131.1 - 1.4 9.4 4.6 0.45 11.0 0.8 2.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain RRM_1 PF00076.22 EEB09132.1 - 5.7e-15 54.9 0.0 9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EEB09132.1 - 4.1e-05 24.0 5.1 0.00026 21.5 0.0 2.6 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 EEB09132.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif DNA_ligase_IV PF11411.8 EEB09132.1 - 0.36 11.0 1.6 0.81 9.9 0.0 2.1 2 0 0 2 2 2 0 DNA ligase IV PAF-AH_p_II PF03403.13 EEB09133.1 - 7.7e-77 258.3 0.0 9.4e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EEB09133.1 - 1.1e-06 27.7 0.1 5.8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EEB09133.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EEB09133.1 - 0.004 16.4 0.3 0.055 12.7 0.1 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EEB09133.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 EEB09133.1 - 0.15 11.8 0.1 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pkinase PF00069.25 EEB09134.1 - 5.9e-71 238.9 0.0 7.4e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09134.1 - 8.6e-35 120.3 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09134.1 - 3.2e-06 26.7 0.0 6.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEB09134.1 - 0.00015 21.8 0.1 0.00027 21.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEB09134.1 - 0.061 12.9 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EEB09134.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 B-block_TFIIIC PF04182.12 EEB09134.1 - 0.071 13.3 0.1 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Haspin_kinase PF12330.8 EEB09134.1 - 0.086 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ANAPC1 PF12859.7 EEB09135.2 - 1.9e-07 31.7 0.1 0.00031 21.3 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EEB09135.2 - 0.00017 21.8 4.2 0.55 10.8 0.0 3.9 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Vezatin PF12632.7 EEB09136.1 - 9e-07 28.5 6.0 2.4e-06 27.2 6.0 1.7 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Topo_Zn_Ribbon PF08272.11 EEB09136.1 - 0.031 13.9 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like PMT PF02366.18 EEB09137.1 - 1.7e-60 204.7 17.6 1.7e-60 204.7 17.6 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEB09137.1 - 7.1e-45 153.1 12.4 7.1e-45 153.1 12.4 2.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEB09137.1 - 7.6e-34 117.2 0.1 1.3e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 MIR domain Hydrolase_like PF13242.6 EEB09138.1 - 1.3e-22 79.6 0.0 6.9e-22 77.3 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEB09138.1 - 2.5e-22 78.9 0.0 4.9e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB09138.1 - 0.029 14.7 0.0 8 6.7 0.0 3.0 2 1 2 4 4 4 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEB09138.1 - 0.029 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EEB09138.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase GATase PF00117.28 EEB09138.1 - 0.11 12.2 0.0 0.52 10.1 0.0 2.0 1 1 1 2 2 2 0 Glutamine amidotransferase class-I PRP21_like_P PF12230.8 EEB09139.1 - 2.5e-53 181.2 7.1 4.3e-53 180.4 7.1 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EEB09139.1 - 2.3e-37 126.7 3.9 2.6e-20 72.1 0.5 2.3 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EEB09139.1 - 0.0081 15.7 0.3 0.018 14.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 EEB09139.1 - 0.12 13.1 0.9 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Di19 PF05605.12 EEB09139.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CDP-OH_P_transf PF01066.21 EEB09140.1 - 9.6e-17 61.5 0.1 9.6e-17 61.5 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Dak1 PF02733.17 EEB09141.1 - 2.8e-111 371.3 3.7 4.9e-111 370.6 3.7 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EEB09141.1 - 7.4e-51 172.5 0.8 1.6e-50 171.4 0.8 1.6 1 0 0 1 1 1 1 DAK2 domain KH_6 PF15985.5 EEB09142.1 - 5.7e-14 52.2 0.1 1.1e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EEB09142.1 - 5.8e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Kelch_6 PF13964.6 EEB09143.2 - 5e-30 102.8 2.2 1.2e-08 35.0 0.0 5.7 4 1 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EEB09143.2 - 1.2e-29 102.0 10.7 1.6e-10 40.8 0.2 5.6 2 1 3 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EEB09143.2 - 2.5e-25 88.2 6.5 9.3e-08 32.2 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EEB09143.2 - 2.8e-24 84.4 0.0 4.9e-07 29.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EEB09143.2 - 2.3e-19 68.9 0.6 1.5e-06 28.1 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EEB09143.2 - 1.4e-11 43.9 0.9 0.00024 21.0 0.0 5.4 5 0 0 5 5 5 2 Kelch motif GIT_CC PF16559.5 EEB09143.2 - 0.13 12.1 13.6 1.1 9.2 2.3 3.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2090 PF09863.9 EEB09143.2 - 0.3 10.1 6.3 1.9 7.5 2.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2090) Abhydrolase_1 PF00561.20 EEB09144.2 - 1.1e-20 74.3 0.0 1.7e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB09144.2 - 3.1e-14 54.1 0.0 6.4e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEB09144.2 - 1.9e-13 50.3 0.0 8.3e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EEB09144.2 - 9e-07 29.0 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 EEB09144.2 - 2.9e-06 27.1 0.0 4.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 EEB09144.2 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 EEB09144.2 - 8.7e-05 22.5 0.1 0.088 12.7 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 EEB09144.2 - 0.00016 21.5 0.0 0.00038 20.2 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.11 EEB09144.2 - 0.001 18.5 0.0 0.008 15.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EEB09144.2 - 0.0029 17.2 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 EEB09144.2 - 0.007 15.1 0.0 0.014 14.1 0.0 1.5 2 0 0 2 2 2 1 Ndr family FSH1 PF03959.13 EEB09144.2 - 0.017 14.8 0.6 0.33 10.6 0.0 2.8 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EEB09144.2 - 0.021 14.3 0.0 0.74 9.3 0.0 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EEB09144.2 - 0.026 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EEB09144.2 - 0.038 14.1 0.1 0.34 11.0 0.0 2.3 2 1 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 EEB09144.2 - 0.039 13.8 0.1 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EEB09144.2 - 0.042 13.6 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EEB09144.2 - 0.087 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2920 PF11144.8 EEB09144.2 - 0.099 11.8 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DUF900 PF05990.12 EEB09144.2 - 0.11 12.0 0.1 0.68 9.4 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_S4e PF00900.20 EEB09145.1 - 4.6e-38 129.0 0.5 8.9e-38 128.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EEB09145.1 - 3.3e-26 90.7 0.0 6e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EEB09145.1 - 5.2e-20 71.3 7.7 1.1e-19 70.2 7.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EEB09145.1 - 8.2e-08 31.8 0.3 1.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EEB09145.1 - 2.5e-06 27.2 2.5 7e-06 25.8 1.1 2.5 2 0 0 2 2 2 1 KOW motif Acatn PF13000.7 EEB09146.1 - 3.2e-106 356.0 33.8 1.9e-61 208.3 14.6 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 LcrR PF09621.10 EEB09147.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Glyco_hydro_16 PF00722.21 EEB09148.1 - 8.3e-08 31.9 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF5316 PF17247.2 EEB09148.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5316) DUF3169 PF11368.8 EEB09148.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Mito_carr PF00153.27 EEB09149.1 - 6e-65 215.2 4.2 1.1e-25 89.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DENN PF02141.21 EEB09150.1 - 1.9e-33 116.0 0.2 4.1e-33 114.9 0.2 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EEB09150.1 - 2.4e-05 25.0 0.0 8.5e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EEB09150.1 - 0.00019 21.4 0.1 0.00074 19.5 0.1 2.2 1 0 0 1 1 1 1 dDENN domain zf-RING_7 PF02591.15 EEB09150.1 - 0.28 11.4 0.9 0.83 9.9 0.9 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain Rrp15p PF07890.12 EEB09151.1 - 2.3e-30 105.7 6.9 4e-30 104.9 6.9 1.4 1 0 0 1 1 1 1 Rrp15p Ndc1_Nup PF09531.10 EEB09151.1 - 0.9 8.1 4.4 0.96 8.1 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rhodanese PF00581.20 EEB09152.1 - 3e-11 43.8 0.1 6.8e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Hexokinase_2 PF03727.16 EEB09153.1 - 1.3e-81 273.5 0.0 2.2e-81 272.8 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EEB09153.1 - 1.4e-72 243.8 0.0 2.6e-72 242.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase TPP_enzyme_N PF02776.18 EEB09153.1 - 0.067 12.8 0.3 0.3 10.7 0.0 2.2 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF1731 PF08338.11 EEB09153.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Cullin PF00888.22 EEB09154.2 - 1.6e-184 615.0 20.4 2.1e-184 614.6 20.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEB09154.2 - 2e-27 95.0 8.5 2.5e-27 94.7 2.4 3.6 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF1041 PF06292.17 EEB09154.2 - 0.046 14.1 1.7 0.22 12.0 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1041) zf-DNL PF05180.12 EEB09155.1 - 3.9e-31 106.8 2.2 5.9e-31 106.2 2.2 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EEB09155.1 - 0.0066 16.5 1.8 0.01 15.9 1.8 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 EEB09155.1 - 0.036 14.0 5.7 2.9 7.9 7.0 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain TFIIS_C PF01096.18 EEB09155.1 - 0.17 11.8 1.9 15 5.5 0.4 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-trcl PF13451.6 EEB09155.1 - 1.4 8.9 5.1 4.2 7.4 1.1 3.1 3 1 0 3 3 3 0 Probable zinc-ribbon domain MBOAT PF03062.19 EEB09156.2 - 1.1e-56 192.7 29.8 1.1e-56 192.7 29.8 2.7 1 1 2 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Dopey_N PF04118.14 EEB09157.2 - 7.4e-95 317.6 0.0 7.4e-95 317.6 0.0 3.6 4 0 0 4 4 4 1 Dopey, N-terminal UvrD-helicase PF00580.21 EEB09157.2 - 0.045 13.3 0.1 0.21 11.1 0.1 2.2 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain SLX9 PF15341.6 EEB09158.2 - 2.1e-19 70.2 18.2 2.1e-19 70.2 18.2 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF4485 PF14846.6 EEB09158.2 - 0.0076 16.3 3.1 0.02 14.9 2.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4485) IL2 PF00715.17 EEB09158.2 - 0.029 14.3 1.8 0.046 13.7 1.8 1.3 1 0 0 1 1 1 0 Interleukin 2 TF_AP-2 PF03299.14 EEB09158.2 - 0.12 12.3 4.3 0.21 11.6 4.3 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 GvpL_GvpF PF06386.11 EEB09158.2 - 1.2 9.0 5.0 0.14 12.1 1.0 1.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF KilA-N PF04383.13 EEB09158.2 - 1.4 8.7 9.1 2.8 7.8 9.0 1.5 1 1 0 1 1 1 0 KilA-N domain EXS PF03124.14 EEB09159.1 - 1.5e-71 241.4 22.1 1.7e-71 241.3 22.1 1.0 1 0 0 1 1 1 1 EXS family SLD3 PF08639.10 EEB09160.1 - 1.7e-22 79.9 21.7 1e-15 57.5 19.5 3.1 2 1 0 2 2 2 2 DNA replication regulator SLD3 S4 PF01479.25 EEB09161.1 - 2.1e-11 43.4 1.4 2.1e-11 43.4 1.4 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EEB09161.1 - 7e-07 30.1 0.3 1.3e-06 29.2 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4194 PF13835.6 EEB09161.1 - 0.011 15.5 1.0 0.02 14.6 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4194) Ras PF00071.22 EEB09162.1 - 3.1e-48 163.4 0.0 5.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB09162.1 - 4.2e-33 114.1 0.2 1e-32 112.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB09162.1 - 3.1e-15 56.1 0.0 4.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEB09162.1 - 4.6e-05 22.9 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB09162.1 - 5.4e-05 23.3 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EEB09162.1 - 9.8e-05 22.2 0.1 0.0011 18.8 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EEB09162.1 - 0.00053 20.3 0.0 0.0034 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EEB09162.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EEB09162.1 - 0.0042 16.7 0.0 0.044 13.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EEB09162.1 - 0.0044 17.5 0.0 0.0088 16.6 0.0 1.8 1 1 1 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EEB09162.1 - 0.0065 16.4 0.0 0.073 13.0 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EEB09162.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEB09162.1 - 0.032 14.4 0.0 0.054 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEB09162.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EEB09162.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EEB09162.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 EEB09162.1 - 0.052 13.9 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 EEB09162.1 - 0.057 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 EEB09162.1 - 0.091 12.8 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Spore_IV_A PF09547.10 EEB09162.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) TniB PF05621.11 EEB09162.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein TetR_C_16 PF17920.1 EEB09162.1 - 0.18 12.1 0.0 0.75 10.1 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sel1 PF08238.12 EEB09164.1 - 1.6e-19 69.9 25.0 4.3e-06 27.2 0.6 10.2 11 0 0 11 11 11 6 Sel1 repeat Noc2 PF03715.13 EEB09165.2 - 1.8e-63 214.6 6.2 3.7e-63 213.6 6.2 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EEB09165.2 - 0.0001 20.7 2.6 0.0001 20.7 2.6 3.0 2 1 0 3 3 3 2 Nop14-like family Pro_sub2 PF18513.1 EEB09165.2 - 0.014 15.6 0.7 0.033 14.4 0.1 2.0 2 0 0 2 2 2 0 Prodomain subtilisin 2 Microtub_bind PF13931.6 EEB09165.2 - 3.3 8.1 8.9 6 7.3 8.0 1.9 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding PCI PF01399.27 EEB09166.2 - 1.5e-10 41.5 0.0 3.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain Coiled-coil_56 PF09813.9 EEB09167.1 - 0.0049 16.9 0.4 0.02 14.9 0.4 1.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 VPS28 PF03997.12 EEB09168.1 - 6.2e-58 195.6 3.0 7.4e-58 195.4 3.0 1.1 1 0 0 1 1 1 1 VPS28 protein DUF4420 PF14390.6 EEB09168.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) DASH_Dad2 PF08654.10 EEB09168.1 - 0.039 14.4 1.6 0.25 11.8 1.5 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF4834 PF16118.5 EEB09168.1 - 0.52 11.3 3.1 0.45 11.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Not3 PF04065.15 EEB09169.1 - 5.5e-87 291.0 27.0 5.5e-87 291.0 27.0 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EEB09169.1 - 1.5e-43 148.0 8.9 2.2e-43 147.5 6.9 2.3 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 EEB09169.1 - 0.014 15.7 1.5 0.014 15.7 1.5 3.3 3 1 0 3 3 3 0 Syntaxin-like protein V-SNARE PF05008.15 EEB09169.1 - 0.022 15.1 7.0 0.071 13.5 1.3 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Cep57_MT_bd PF06657.13 EEB09169.1 - 0.05 14.1 0.3 0.05 14.1 0.3 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.9 EEB09169.1 - 0.06 13.2 2.2 0.15 11.9 2.2 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) ATG_C PF09333.11 EEB09169.1 - 0.25 11.7 3.4 0.22 11.9 0.8 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain LepA_C PF06421.12 EEB09170.2 - 3.8e-41 139.6 0.6 9.1e-41 138.4 0.4 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 EEB09170.2 - 1.2e-40 139.1 0.0 3.6e-39 134.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EEB09170.2 - 2e-19 69.4 0.0 4.5e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus SRPRB PF09439.10 EEB09170.2 - 3.4e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EEB09170.2 - 6e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEB09170.2 - 0.00042 20.4 0.0 0.0008 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EEB09170.2 - 0.00071 19.9 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 EEB09170.2 - 0.016 14.8 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 Ras family RF3_C PF16658.5 EEB09170.2 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Pro_isomerase PF00160.21 EEB09171.1 - 1.2e-46 158.8 0.4 2e-46 158.2 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EEB09171.1 - 1.2e-05 25.0 3.8 0.025 14.7 1.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEB09171.1 - 0.0012 18.6 0.8 0.072 12.9 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEB09171.1 - 0.0025 18.4 3.1 0.4 11.4 0.7 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09171.1 - 0.074 13.6 0.8 0.15 12.5 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEB09171.1 - 0.13 12.5 0.6 0.7 10.3 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Elf1 PF05129.13 EEB09172.2 - 3.6e-31 107.0 1.3 4.3e-31 106.8 1.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.6 EEB09173.2 - 3.7e-78 261.7 0.0 4.2e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEB09173.2 - 5e-06 26.1 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.6 EEB09173.2 - 0.013 15.9 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain TIP49 PF06068.13 EEB09174.1 - 1.4e-169 563.9 0.2 1.7e-169 563.6 0.2 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEB09174.1 - 7.6e-25 86.8 0.1 1.9e-24 85.6 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EEB09174.1 - 1.9e-10 41.3 0.4 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEB09174.1 - 7.5e-08 32.3 0.1 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEB09174.1 - 6.7e-05 23.3 0.4 0.0082 16.5 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EEB09174.1 - 0.00016 22.0 0.1 0.78 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EEB09174.1 - 0.00094 19.5 0.2 0.0032 17.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EEB09174.1 - 0.0026 17.8 0.1 0.2 11.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EEB09174.1 - 0.0029 17.6 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EEB09174.1 - 0.0066 15.9 0.1 0.6 9.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EEB09174.1 - 0.0074 16.0 0.1 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EEB09174.1 - 0.011 15.8 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EEB09174.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EEB09174.1 - 0.032 14.0 0.4 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EEB09174.1 - 0.034 14.3 0.1 0.11 12.7 0.0 1.9 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EEB09174.1 - 0.051 13.1 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEB09174.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EEB09174.1 - 0.12 12.4 0.0 5.1 7.2 0.2 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EEB09174.1 - 0.17 11.3 0.1 0.79 9.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Proteasome PF00227.26 EEB09175.1 - 1.2e-50 171.6 0.0 1.8e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEB09175.1 - 1.7e-12 46.8 0.0 3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HAD_2 PF13419.6 EEB09175.1 - 0.098 12.7 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 EEB09175.1 - 0.19 12.4 9.7 0.43 11.2 9.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAPPC9-Trs120 PF08626.11 EEB09176.1 - 5e-287 955.0 0.3 6.4e-287 954.6 0.3 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HTH_11 PF08279.12 EEB09176.1 - 0.026 14.5 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 HTH domain DAO PF01266.24 EEB09177.2 - 1.6e-57 195.7 0.0 1.8e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEB09177.2 - 0.00061 20.0 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EEB09177.2 - 0.0056 15.6 0.2 0.12 11.2 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EEB09177.2 - 0.013 14.8 0.1 0.64 9.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB09177.2 - 0.015 15.3 0.3 3.3 7.7 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EEB09177.2 - 0.024 13.9 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MIF4G_like PF09088.11 EEB09178.1 - 6.3e-78 260.9 0.6 1.4e-77 259.8 0.6 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EEB09178.1 - 6e-35 121.0 1.9 1e-34 120.2 1.9 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 EEB09178.1 - 0.029 14.0 1.8 0.086 12.5 1.8 1.9 1 1 0 1 1 1 0 MIF4G domain Iso_dh PF00180.20 EEB09179.2 - 2e-74 250.8 0.0 2.4e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_63 PF03200.16 EEB09180.1 - 3.5e-174 580.2 2.9 4.5e-173 576.5 2.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EEB09180.1 - 5.8e-64 216.3 0.0 8.8e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EEB09180.1 - 1.3e-06 27.5 0.0 1.3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid6H PF17389.2 EEB09180.1 - 0.05 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MMtag PF10159.9 EEB09181.1 - 5.5e-27 93.9 4.9 5.5e-27 93.9 4.9 2.1 2 1 0 2 2 2 1 Multiple myeloma tumor-associated SelP_N PF04592.14 EEB09181.1 - 0.45 9.9 12.6 0.7 9.3 12.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HNOBA PF07701.14 EEB09181.1 - 1.5 8.2 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated zf-met2 PF12907.7 EEB09182.1 - 6.6e-21 74.2 0.1 1e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EEB09182.1 - 0.00011 23.0 8.2 0.00018 22.3 8.2 1.3 1 0 0 1 1 1 1 4F5 protein family zf-Di19 PF05605.12 EEB09182.1 - 0.21 11.9 1.9 2.4 8.5 1.4 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CAS_CSE1 PF03378.15 EEB09183.1 - 8.4e-153 509.0 0.2 1.6e-152 508.1 0.2 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EEB09183.1 - 1.7e-148 494.4 5.4 2.6e-148 493.8 5.4 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EEB09183.1 - 1.4e-15 56.9 0.1 6e-15 54.9 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EEB09183.1 - 0.024 14.7 2.1 0.087 12.9 0.1 3.1 4 0 0 4 4 4 0 Exportin 1-like protein GIDA PF01134.22 EEB09184.1 - 2e-146 488.1 0.0 2.6e-146 487.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EEB09184.1 - 7e-61 206.1 0.2 9.8e-61 205.6 0.2 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EEB09184.1 - 9.2e-08 31.7 0.5 7.5e-07 28.7 0.3 2.5 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEB09184.1 - 1.2e-05 24.9 0.2 2e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EEB09184.1 - 0.00035 19.9 0.1 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEB09184.1 - 0.00066 18.9 2.3 0.0011 18.1 1.6 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EEB09184.1 - 0.0028 16.9 0.7 0.067 12.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EEB09184.1 - 0.003 16.3 3.1 0.0059 15.4 0.5 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 EEB09184.1 - 0.0074 16.8 0.1 0.019 15.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEB09184.1 - 0.02 14.2 0.1 0.054 12.8 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EEB09184.1 - 0.029 13.4 0.2 0.088 11.8 0.2 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EEB09184.1 - 0.042 13.9 1.5 0.079 13.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Syntaxin-6_N PF09177.11 EEB09184.1 - 0.098 13.2 0.0 0.34 11.5 0.0 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Pox_L3_FP4 PF03339.14 EEB09184.1 - 0.11 11.5 0.1 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Poxvirus L3/FP4 protein Thi4 PF01946.17 EEB09184.1 - 0.16 11.1 0.1 0.39 9.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Tfb4 PF03850.14 EEB09185.1 - 1.1e-105 353.1 3.0 1.3e-105 352.9 3.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF1246 PF06849.12 EEB09185.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) RNase_T PF00929.24 EEB09186.1 - 1.4e-18 68.0 0.0 6e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Exonuclease SAP PF02037.27 EEB09186.1 - 0.00063 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF5051 PF16473.5 EEB09186.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like DUF3289 PF11692.8 EEB09186.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) MMM1 PF10296.9 EEB09187.2 - 1.3e-84 284.1 10.2 1.3e-80 271.0 10.2 3.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 TPR_1 PF00515.28 EEB09188.1 - 1.9e-37 125.6 18.6 3e-06 26.8 0.4 8.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EEB09188.1 - 1.7e-33 112.0 15.4 1.3e-06 28.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 EEB09188.1 - 1.2e-27 95.8 5.1 5.1e-27 93.8 3.5 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 EEB09188.1 - 6.6e-21 73.7 13.7 1.5e-05 24.6 1.0 6.2 3 1 2 5 5 5 4 TPR repeat TPR_16 PF13432.6 EEB09188.1 - 6.8e-20 71.4 11.7 1.1e-06 29.2 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEB09188.1 - 1e-18 65.9 15.3 0.018 15.2 0.2 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09188.1 - 1.1e-16 61.1 12.6 2.1e-06 28.2 0.1 5.9 6 1 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEB09188.1 - 1.2e-16 59.9 10.2 0.012 16.4 0.0 8.1 3 3 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEB09188.1 - 5.9e-16 58.5 16.2 7.7e-05 22.9 1.6 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB09188.1 - 2.5e-14 53.3 9.0 9.3e-05 22.6 0.5 4.3 5 0 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EEB09188.1 - 5.9e-13 48.8 7.7 0.00023 21.2 0.0 5.6 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEB09188.1 - 3e-09 36.2 11.4 0.03 14.3 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEB09188.1 - 2.1e-08 34.0 20.2 0.00019 21.5 0.1 7.4 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EEB09188.1 - 2.7e-08 33.4 9.5 0.0039 16.4 0.1 4.5 2 2 0 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEB09188.1 - 3.6e-06 26.9 5.4 0.011 15.7 0.1 5.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EEB09188.1 - 4.9e-06 26.8 13.0 0.021 15.4 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EEB09188.1 - 2.6e-05 23.8 1.0 0.00077 18.9 0.0 3.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 EEB09188.1 - 3.2e-05 23.7 9.9 0.2 11.6 1.5 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EEB09188.1 - 5.8e-05 23.6 2.7 0.02 15.4 0.1 3.1 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation TPR_21 PF09976.9 EEB09188.1 - 0.0024 17.6 7.6 0.087 12.5 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat-like domain HEAT_2 PF13646.6 EEB09188.1 - 0.0031 17.8 0.0 0.014 15.7 0.0 2.2 1 1 0 1 1 1 1 HEAT repeats DUF2989 PF11207.8 EEB09188.1 - 0.083 12.6 1.7 6.3 6.5 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) MIT PF04212.18 EEB09188.1 - 0.12 12.5 0.5 0.12 12.5 0.5 6.5 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain RPT PF13446.6 EEB09188.1 - 0.13 12.2 3.0 0.31 11.0 0.0 3.2 5 0 0 5 5 3 0 A repeated domain in UCH-protein HemY_N PF07219.13 EEB09188.1 - 0.15 12.3 3.5 23 5.2 0.0 4.0 2 1 1 4 4 4 0 HemY protein N-terminus DUF4192 PF13830.6 EEB09188.1 - 0.35 10.9 2.1 0.55 10.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Sel1 PF08238.12 EEB09188.1 - 0.87 10.4 4.1 23 5.8 0.0 4.2 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.12 EEB09188.1 - 9.3 6.4 17.1 0.96 9.5 0.4 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Ku PF02735.16 EEB09189.1 - 1.9e-33 115.9 0.0 3.8e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EEB09189.1 - 2.1e-12 47.3 0.0 6.4e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Ku C terminal domain like Fungal_trans PF04082.18 EEB09190.1 - 1.6e-12 47.0 3.0 2.7e-12 46.3 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB09191.1 - 7.5e-11 42.0 9.7 1.1e-10 41.5 9.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.18 EEB09192.1 - 1.2e-97 326.6 0.1 2.2e-97 325.7 0.0 1.4 1 1 1 2 2 2 1 Septin DUF1690 PF07956.11 EEB09192.1 - 0.038 14.4 1.6 0.12 12.8 1.6 1.8 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DLP_helical PF18709.1 EEB09192.1 - 0.098 11.8 2.2 3.1 6.9 1.7 2.2 2 0 0 2 2 2 0 Dynamin-like helical domain PSP1 PF04468.12 EEB09192.1 - 0.11 12.8 0.8 10 6.5 0.4 2.8 2 1 0 2 2 2 0 PSP1 C-terminal conserved region ADH_zinc_N PF00107.26 EEB09193.1 - 3.2e-20 72.4 0.0 6.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEB09193.1 - 3.2e-19 70.3 0.0 6.2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEB09193.1 - 5e-08 32.8 0.0 8.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EEB09193.1 - 0.00047 19.9 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YjeF_N PF03853.15 EEB09193.1 - 0.0091 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 EEB09193.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEB09193.1 - 0.025 13.9 0.9 0.046 13.0 0.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 EEB09193.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EEB09193.1 - 0.051 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 EEB09193.1 - 0.066 13.0 0.5 0.2 11.5 0.3 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MRP-S25 PF13741.6 EEB09195.2 - 5.2e-68 229.0 4.1 7.1e-68 228.6 4.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 FANC_SAP PF18081.1 EEB09195.2 - 0.33 11.1 3.2 1.5 9.0 0.5 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain WD40 PF00400.32 EEB09196.1 - 8.9e-22 77.0 3.8 0.0014 19.5 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09196.1 - 2.2e-10 40.7 0.0 0.057 13.7 0.0 4.9 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB09196.1 - 0.00017 20.7 0.6 0.28 10.1 0.0 3.1 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEB09196.1 - 0.0012 17.6 0.1 0.0088 14.7 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EEB09196.1 - 0.0023 17.3 0.0 0.013 14.8 0.0 1.9 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 EEB09196.1 - 0.037 13.9 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cadherin_4 PF17803.1 EEB09196.1 - 0.092 13.4 0.5 0.35 11.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial cadherin-like domain A_deamin PF02137.18 EEB09197.2 - 1.8e-41 142.7 0.2 3e-41 141.9 0.2 1.3 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Whi5 PF08528.11 EEB09198.1 - 9.4e-10 37.9 0.3 1.8e-09 37.0 0.3 1.5 1 0 0 1 1 1 1 Whi5 like Stm1_N PF09598.10 EEB09200.2 - 1.5e-12 48.1 8.1 1.5e-12 48.1 8.1 4.0 2 1 0 2 2 2 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EEB09200.2 - 1.8 9.4 24.4 0.14 13.0 1.7 3.8 2 1 2 4 4 4 0 Hyaluronan / mRNA binding family UFD1 PF03152.14 EEB09201.1 - 4e-74 247.8 0.0 5e-74 247.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 EEB09201.1 - 0.0029 17.7 0.0 4.5 7.5 0.0 2.8 3 0 0 3 3 3 2 Cell division protein 48 (CDC48), N-terminal domain RRM_1 PF00076.22 EEB09202.1 - 1.3e-09 37.7 0.1 2.9e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilX_N PF14341.6 EEB09202.1 - 0.041 13.8 0.5 0.098 12.6 0.5 1.6 1 0 0 1 1 1 0 PilX N-terminal DUF1948 PF09185.10 EEB09202.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Tubulin PF00091.25 EEB09203.1 - 1.1e-66 224.8 0.0 1.6e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEB09203.1 - 1.1e-50 171.0 0.1 1.9e-50 170.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EEB09203.1 - 0.0051 16.5 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain HSF_DNA-bind PF00447.17 EEB09204.2 - 5.6e-31 107.0 0.1 1.1e-30 106.1 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding YabA PF06156.13 EEB09204.2 - 0.065 13.9 2.0 0.19 12.4 2.0 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Myb_DNA-binding PF00249.31 EEB09205.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain GCIP PF13324.6 EEB09206.1 - 6.4e-22 78.4 3.0 6.4e-22 78.4 3.0 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting ArfGap PF01412.18 EEB09207.1 - 5e-33 113.6 1.2 1.1e-32 112.5 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PI3_PI4_kinase PF00454.27 EEB09208.2 - 8.9e-20 71.6 0.0 4.8e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.25 EEB09209.1 - 1.6e-67 227.6 0.0 2.2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09209.1 - 6.3e-28 97.8 0.0 9.2e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEB09209.1 - 5.2e-10 39.9 4.3 1.8e-09 38.1 4.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEB09209.1 - 2e-07 30.7 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EEB09209.1 - 0.00067 19.4 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EEB09209.1 - 0.0082 15.1 0.0 0.016 14.2 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEB09209.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEB09209.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L24e PF01246.20 EEB09210.1 - 1.1e-33 115.2 5.2 1.1e-33 115.2 5.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e DUF5078 PF16877.5 EEB09210.1 - 0.0074 16.8 0.5 0.015 15.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5078) DUF4672 PF15716.5 EEB09210.1 - 0.34 10.5 8.9 1.2 8.7 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4672) PHD PF00628.29 EEB09211.2 - 8e-10 38.5 9.6 2e-09 37.2 9.6 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EEB09211.2 - 2.4e-07 31.3 0.2 9.8e-06 26.1 0.0 2.9 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.6 EEB09211.2 - 0.016 14.7 3.7 0.039 13.5 3.7 1.7 1 0 0 1 1 1 0 PHD-finger COX15-CtaA PF02628.15 EEB09212.1 - 1.6e-107 359.3 10.6 2e-107 359.0 10.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fer2 PF00111.27 EEB09212.1 - 9.7e-13 47.9 0.3 1.5e-12 47.2 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_S8 PF00082.22 EEB09213.1 - 1.3e-32 113.3 0.1 1.3e-32 113.3 0.1 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 EEB09213.1 - 2.3e-26 91.6 0.5 4.7e-26 90.6 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 EEB09213.1 - 0.015 15.7 0.2 0.044 14.3 0.1 1.8 2 0 0 2 2 2 0 N-terminal of Subtilase family MGC-24 PF05283.11 EEB09213.1 - 0.019 15.4 2.5 0.019 15.4 2.5 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pyr_redox_2 PF07992.14 EEB09214.1 - 1.7e-40 139.1 0.0 1.9e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEB09214.1 - 2.4e-16 59.9 0.3 6.1e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEB09214.1 - 7.8e-13 48.8 3.2 5e-11 43.0 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEB09214.1 - 6.2e-05 22.4 2.1 0.05 12.8 0.1 3.0 2 1 1 3 3 3 2 Thi4 family NAD_binding_8 PF13450.6 EEB09214.1 - 0.015 15.5 0.3 0.21 11.9 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EEB09214.1 - 0.02 14.0 3.6 2.2 7.3 0.4 2.5 2 2 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 EEB09214.1 - 0.047 12.8 0.4 0.49 9.5 0.1 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EEB09214.1 - 0.079 12.3 1.4 0.24 10.7 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase UAF_Rrn10 PF05234.11 EEB09215.1 - 8.8e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 LRR_6 PF13516.6 EEB09216.1 - 4.2e-15 54.4 0.1 0.068 13.3 0.1 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EEB09216.1 - 8.7e-10 38.7 6.3 0.2 12.1 0.1 6.1 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEB09216.1 - 0.0017 18.6 3.0 41 5.3 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 EEB09216.1 - 0.13 12.1 13.3 4.8 7.0 0.2 5.7 3 3 1 4 4 4 0 Leucine rich repeat NOA36 PF06524.12 EEB09216.1 - 7.8 5.7 7.4 12 5.1 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_34 PF05637.12 EEB09217.1 - 1e-78 264.3 0.3 1.2e-78 264.1 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 EEB09217.1 - 0.0052 16.8 0.1 0.0094 15.9 0.1 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Rer1 PF03248.13 EEB09218.1 - 1.3e-74 249.6 11.2 1.6e-74 249.4 11.2 1.0 1 0 0 1 1 1 1 Rer1 family DJ-1_PfpI PF01965.24 EEB09220.1 - 1.7e-41 141.8 0.0 2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DUF441 PF04284.13 EEB09220.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF441) RRM_1 PF00076.22 EEB09221.1 - 2.8e-19 68.7 0.0 4.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPT PF03151.16 EEB09222.1 - 2.2e-16 60.1 17.9 3.3e-15 56.2 8.9 2.0 1 1 1 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EEB09222.1 - 0.00015 21.9 17.4 0.00015 21.9 17.4 2.2 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 EEB09222.1 - 0.0005 19.4 11.5 0.00072 18.8 11.5 1.2 1 0 0 1 1 1 1 UAA transporter family DUF5090 PF17009.5 EEB09222.1 - 0.023 14.7 1.5 0.023 14.7 1.5 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) Phage_tail_T PF06223.12 EEB09222.1 - 0.093 13.3 0.6 0.32 11.5 0.1 2.0 2 0 0 2 2 2 0 Minor tail protein T CAF1 PF04857.20 EEB09223.1 - 5e-18 65.3 0.6 1.5e-08 34.2 0.4 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease RNA_pol_Rpc4 PF05132.14 EEB09224.1 - 2.2e-23 83.3 2.0 6.5e-23 81.8 0.0 2.7 3 1 0 3 3 3 1 RNA polymerase III RPC4 tRNA-synt_2 PF00152.20 EEB09225.1 - 6.2e-63 212.8 0.0 7.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EEB09225.1 - 4.2e-09 36.3 0.0 3.9e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EEB09225.1 - 2.4e-08 33.8 0.1 5.3e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DcpS_C PF11969.8 EEB09226.2 - 6e-17 62.2 2.1 1.5e-16 60.9 2.1 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EEB09226.2 - 7.5e-17 61.9 0.1 1.8e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 EEB09226.2 - 5.8e-08 33.1 1.1 1.8e-07 31.5 1.1 1.9 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Orthopox_F14 PF06076.12 EEB09226.2 - 0.058 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Arm PF00514.23 EEB09227.1 - 1e-96 314.3 23.7 1.4e-13 50.4 0.2 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEB09227.1 - 3.2e-24 85.0 4.8 1.2e-09 38.4 0.1 7.2 5 2 3 8 8 8 5 HEAT-like repeat IBB PF01749.20 EEB09227.1 - 1.3e-23 83.2 3.0 3.2e-23 82.0 3.0 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EEB09227.1 - 4.1e-21 74.3 1.1 1.2e-20 72.8 1.1 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EEB09227.1 - 4.6e-20 71.8 1.5 1e-07 32.2 0.0 6.1 2 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 EEB09227.1 - 1.4e-18 65.4 1.1 0.00015 21.7 0.0 7.5 7 0 0 7 7 7 3 HEAT repeat V-ATPase_H_C PF11698.8 EEB09227.1 - 4.1e-09 36.6 0.2 0.074 13.2 0.0 5.0 4 1 0 5 5 5 2 V-ATPase subunit H Arm_2 PF04826.13 EEB09227.1 - 3.7e-08 33.1 1.0 0.001 18.6 0.0 4.1 2 1 3 5 5 5 2 Armadillo-like Adaptin_N PF01602.20 EEB09227.1 - 4.8e-08 32.0 0.2 0.00027 19.6 0.1 2.5 1 1 1 2 2 2 2 Adaptin N terminal region CTNNBL PF08216.11 EEB09227.1 - 1.8e-06 28.1 1.6 2.2 8.5 0.0 5.9 5 1 1 6 6 6 1 Catenin-beta-like, Arm-motif containing nuclear NopRA1 PF16201.5 EEB09227.1 - 2e-06 27.5 0.0 1.6 8.3 0.0 4.8 2 1 3 5 5 5 3 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 EEB09227.1 - 1.1e-05 25.6 2.9 2.2 8.6 0.0 5.2 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 EEB09227.1 - 0.00019 21.4 0.0 4.8 7.3 0.0 4.4 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EEB09227.1 - 0.0007 20.0 0.6 1.8 9.4 0.0 5.1 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 EEB09227.1 - 0.003 16.9 0.0 0.56 9.5 0.0 3.2 1 1 1 2 2 2 1 V-ATPase subunit H DUF3552 PF12072.8 EEB09227.1 - 0.011 15.2 4.8 0.019 14.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Proteasom_PSMB PF10508.9 EEB09227.1 - 0.018 13.6 0.1 3.6 6.0 0.0 3.0 1 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF5615 PF18480.1 EEB09227.1 - 0.072 12.9 0.1 29 4.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5615) DUF349 PF03993.12 EEB09227.1 - 0.073 13.4 4.9 0.16 12.3 4.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DCB PF16213.5 EEB09227.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 BIR PF00653.21 EEB09228.2 - 1e-43 147.8 2.8 3.7e-21 75.5 0.6 2.9 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EEB09228.2 - 0.0011 19.1 3.1 0.09 12.8 0.3 3.7 3 1 0 3 3 3 2 C3HC zinc finger-like C2 PF00168.30 EEB09229.1 - 3.5e-48 162.2 0.2 6.7e-18 64.9 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EEB09229.1 - 0.00075 19.0 0.2 0.0038 16.7 0.2 2.0 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain UPF0444 PF15475.6 EEB09229.1 - 0.00098 19.3 1.2 0.00098 19.3 1.2 2.7 1 1 1 2 2 2 1 Transmembrane protein C12orf23, UPF0444 DUF4083 PF13314.6 EEB09229.1 - 0.037 14.0 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Ribosomal_L35Ae PF01247.18 EEB09230.1 - 1.5e-40 137.2 0.2 1.7e-40 137.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EEB09230.1 - 0.00077 19.6 0.0 0.86 9.9 0.0 2.5 2 1 1 3 3 3 2 RimM N-terminal domain GTP_EFTU PF00009.27 EEB09231.2 - 2e-65 220.0 0.1 2.9e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEB09231.2 - 1.6e-30 105.4 0.0 4.8e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EEB09231.2 - 3e-20 72.0 0.0 6.8e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB09231.2 - 1.6e-12 47.6 0.0 4.7e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEB09231.2 - 1.8e-12 47.2 0.0 4.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEB09231.2 - 0.00065 19.8 0.1 0.0014 18.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase C2 PF00168.30 EEB09232.1 - 3.5e-29 101.1 0.0 4.1e-14 52.7 0.0 3.0 3 0 0 3 3 3 2 C2 domain Tyr-DNA_phospho PF06087.12 EEB09233.1 - 1.9e-116 389.5 0.0 2.2e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF4448 PF14610.6 EEB09234.1 - 4.6e-28 98.3 0.8 6.1e-28 97.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3899 PF13038.6 EEB09234.1 - 0.07 13.6 1.4 0.29 11.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) TMEM154 PF15102.6 EEB09234.1 - 0.73 9.7 0.0 0.73 9.7 0.0 2.4 3 0 0 3 3 3 0 TMEM154 protein family TFB6 PF17110.5 EEB09235.1 - 2.1e-10 40.6 6.7 1.3e-08 34.8 6.7 2.8 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH PA26 PF04636.13 EEB09235.1 - 0.007 15.3 0.0 0.0078 15.2 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Mst1_SARAH PF11629.8 EEB09235.1 - 0.0097 16.0 1.9 0.012 15.6 0.2 2.1 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Sec23_helical PF04815.15 EEB09235.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.5 1 1 0 1 1 1 0 Sec23/Sec24 helical domain LisH PF08513.11 EEB09236.1 - 2e-08 33.9 0.9 4.8e-08 32.7 0.9 1.7 1 0 0 1 1 1 1 LisH MAJIN PF15077.6 EEB09236.1 - 1.5 8.6 12.2 0.071 12.9 2.1 2.7 2 0 0 2 2 2 0 Membrane-anchored junction protein IATP PF04568.12 EEB09237.1 - 5.6e-09 36.3 0.2 7.3e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FapA PF03961.13 EEB09237.1 - 0.0018 16.9 1.4 0.0019 16.9 1.4 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Spectrin PF00435.21 EEB09237.1 - 0.0034 17.8 5.7 0.0046 17.4 5.7 1.1 1 0 0 1 1 1 1 Spectrin repeat BLOC1_2 PF10046.9 EEB09237.1 - 0.0037 17.5 2.4 0.0052 17.1 2.4 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 EEB09237.1 - 0.0075 16.5 1.9 0.011 15.9 1.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein PRKG1_interact PF15898.5 EEB09237.1 - 0.024 15.5 8.2 0.036 15.0 8.2 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 EEB09237.1 - 0.14 12.4 6.0 0.18 12.1 6.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4191 PF13829.6 EEB09237.1 - 0.15 11.4 0.4 0.19 11.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) XhlA PF10779.9 EEB09237.1 - 0.4 10.9 3.2 0.59 10.4 3.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TMPIT PF07851.13 EEB09237.1 - 5.2 6.2 6.7 6.4 5.9 6.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein ArAE_2_N PF10337.9 EEB09238.1 - 4e-62 210.8 16.3 1.9e-55 188.8 6.7 3.1 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EEB09238.1 - 2.8e-59 200.7 0.0 4.3e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EEB09238.1 - 2.7e-07 30.8 15.5 2.7e-07 30.8 15.5 3.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like Utp14 PF04615.13 EEB09239.1 - 1.2e-183 612.7 75.5 1.2e-183 612.7 75.5 2.0 1 1 1 2 2 2 1 Utp14 protein S-methyl_trans PF02574.16 EEB09240.1 - 1.7e-36 126.4 0.0 1.9e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Metallophos PF00149.28 EEB09241.1 - 3.7e-34 119.0 0.0 5.5e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEB09241.1 - 1.8e-17 63.5 0.1 3.5e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RRM_1 PF00076.22 EEB09242.1 - 6.6e-86 282.2 6.2 3.3e-21 74.9 0.8 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EEB09242.1 - 1.6e-26 92.2 3.5 2.4e-26 91.7 0.5 2.8 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EEB09242.1 - 6e-12 45.3 1.6 0.12 12.0 0.1 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB09242.1 - 3.3e-07 30.3 0.6 2 8.6 0.0 5.1 4 2 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 EEB09242.1 - 2.6e-05 24.2 7.7 1.5 8.9 3.3 4.4 3 1 1 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 EEB09242.1 - 0.00011 22.1 1.9 7.9 6.6 0.1 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EEB09242.1 - 0.00033 20.4 0.0 0.084 12.7 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif YflT PF11181.8 EEB09242.1 - 0.0023 18.4 6.0 0.38 11.3 1.1 3.3 3 0 0 3 3 3 2 Heat induced stress protein YflT CbiG_mid PF11761.8 EEB09242.1 - 0.0027 17.8 0.0 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis central region DUF4523 PF15023.6 EEB09242.1 - 0.0033 17.3 0.0 4.5 7.1 0.0 3.5 2 2 2 4 4 4 1 Protein of unknown function (DUF4523) Calcipressin PF04847.12 EEB09242.1 - 0.029 14.1 1.5 0.27 11.0 0.4 2.9 3 0 0 3 3 3 0 Calcipressin Nefa_Nip30_N PF10187.9 EEB09242.1 - 0.036 14.4 0.5 0.036 14.4 0.5 3.3 4 0 0 4 4 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PHM7_cyt PF14703.6 EEB09242.1 - 0.64 10.2 7.2 17 5.6 1.1 4.5 3 1 1 5 5 4 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 EEB09242.1 - 0.75 9.5 2.4 5.4 6.8 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain DnaI_N PF07319.11 EEB09242.1 - 1.3 9.7 6.4 0.4 11.4 1.0 2.8 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus PET117 PF15786.5 EEB09242.1 - 4.3 7.7 7.2 3.5 8.0 2.1 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial HECT PF00632.25 EEB09244.1 - 6.8e-95 318.1 0.2 2.2e-94 316.4 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EEB09244.1 - 0.038 13.8 0.6 0.16 11.8 0.6 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Usp PF00582.26 EEB09246.1 - 1.7e-27 96.6 0.4 1.7e-27 96.6 0.4 2.1 2 1 0 2 2 2 1 Universal stress protein family Pam17 PF08566.10 EEB09247.2 - 2.1e-59 200.1 0.3 2.8e-59 199.6 0.0 1.3 2 0 0 2 2 2 1 Mitochondrial import protein Pam17 Fer4_NifH PF00142.18 EEB09247.2 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SART-1 PF03343.13 EEB09248.2 - 2e-116 390.1 47.6 2.4e-116 389.8 47.6 1.0 1 0 0 1 1 1 1 SART-1 family Virulence_fact PF13769.6 EEB09248.2 - 2 8.7 9.7 4.7 7.5 3.7 3.2 2 0 0 2 2 2 0 Virulence factor Prenyltrans PF00432.21 EEB09249.1 - 1.9e-59 197.1 2.2 1.7e-14 53.2 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EEB09249.1 - 2.1e-07 30.3 0.0 0.078 12.1 0.0 3.8 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EEB09249.1 - 8.6e-05 21.8 0.0 0.0076 15.4 0.0 2.6 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Rop PF01815.16 EEB09249.1 - 0.089 12.7 1.5 1.1 9.2 0.0 3.2 4 0 0 4 4 4 0 Rop protein Ribonuc_2-5A PF06479.12 EEB09250.1 - 1e-45 155.0 0.2 1.9e-45 154.1 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EEB09250.1 - 6.8e-39 133.8 0.0 2.3e-38 132.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09250.1 - 1e-21 77.4 0.0 2.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EEB09250.1 - 2.6e-10 39.7 2.7 0.0033 17.3 0.1 3.9 3 1 1 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 EEB09250.1 - 2.1e-06 27.5 0.0 8.5e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 PQQ-like domain Pkinase_fungal PF17667.1 EEB09250.1 - 0.00046 19.1 0.0 0.093 11.5 0.0 2.4 2 1 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 EEB09250.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 EEB09250.1 - 0.039 14.5 0.1 23 5.7 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain AP3D1 PF06375.11 EEB09250.1 - 0.33 11.2 4.7 0.68 10.2 4.7 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 4F5 PF04419.14 EEB09251.1 - 5.6e-08 33.5 10.3 5.6e-08 33.5 10.3 2.3 1 1 1 2 2 2 1 4F5 protein family zf-CCHC PF00098.23 EEB09252.2 - 8e-07 28.9 1.5 1.6e-06 27.9 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EEB09252.2 - 0.008 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 EEB09252.2 - 0.024 14.4 1.2 0.024 14.4 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 EEB09252.2 - 0.07 12.8 5.1 0.14 11.9 5.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger EF-hand_6 PF13405.6 EEB09252.2 - 0.15 12.1 0.0 0.47 10.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain HAD PF12710.7 EEB09253.1 - 2.8e-22 80.1 0.0 5e-22 79.2 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB09253.1 - 2.4e-18 67.2 0.9 4.5e-18 66.3 0.9 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEB09253.1 - 8.5e-12 45.3 0.3 3.2e-08 33.6 0.1 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EEB09253.1 - 0.00017 21.1 0.0 0.00094 18.6 0.0 1.9 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.6 EEB09253.1 - 0.00094 19.3 0.1 0.0042 17.2 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EEB09253.1 - 0.054 13.0 0.1 1.5 8.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) DUF705 PF05152.12 EEB09253.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) AHSA1 PF08327.11 EEB09254.2 - 0.08 13.2 0.1 0.092 13.0 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein DHHC PF01529.20 EEB09255.1 - 6.5e-37 126.6 14.5 6.5e-37 126.6 14.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase ABC2_membrane_3 PF12698.7 EEB09255.1 - 0.35 9.9 9.8 0.06 12.5 0.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein zf-RanBP PF00641.18 EEB09255.1 - 5.5 6.4 7.1 0.34 10.3 1.4 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ELP6 PF09807.9 EEB09256.1 - 2.2e-10 40.4 0.2 3e-10 39.9 0.2 1.3 1 1 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 EEB09256.1 - 0.0046 16.3 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 KaiC Methyltransf_23 PF13489.6 EEB09257.1 - 5.3e-18 65.4 0.0 6.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB09257.1 - 1.3e-16 61.1 0.0 2.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB09257.1 - 1.3e-15 57.8 0.0 2.7e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB09257.1 - 1e-13 51.7 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB09257.1 - 2.8e-10 40.2 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEB09257.1 - 2.7e-07 30.3 0.0 4.9e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EEB09257.1 - 2.4e-06 27.0 0.0 8.3e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EEB09257.1 - 0.0002 20.7 0.0 0.0025 17.0 0.0 1.9 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family NodS PF05401.11 EEB09257.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF938 PF06080.12 EEB09257.1 - 0.0018 18.0 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) CMAS PF02353.20 EEB09257.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EEB09257.1 - 0.034 15.2 0.0 0.063 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EEB09257.1 - 0.043 13.3 0.0 0.24 10.8 0.0 2.2 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 EEB09257.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EEB09257.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rogdi_lz PF10259.9 EEB09258.1 - 2.4e-21 76.4 1.5 9.6e-20 71.1 1.5 2.0 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein FHA PF00498.26 EEB09259.1 - 3.1e-19 69.1 0.1 6.7e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEB09259.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BRCT_2 PF16589.5 EEB09260.1 - 0.018 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 EEB09261.1 - 1.9e-26 93.0 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09261.1 - 7.5e-15 54.9 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB09261.1 - 4.7e-10 38.8 0.1 7.7e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEB09261.1 - 2e-05 24.7 0.0 0.0023 17.9 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family ox_reductase_C PF08635.10 EEB09262.1 - 1.1e-69 232.5 0.0 1.6e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EEB09262.1 - 5.5e-14 53.0 0.0 9.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEB09262.1 - 0.0073 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain FAD_binding_1 PF00667.20 EEB09263.2 - 4.7e-57 193.1 0.0 7.3e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEB09263.2 - 2.5e-13 50.6 0.0 8.9e-11 42.4 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain RICTOR_N PF14664.6 EEB09264.1 - 1e-82 278.1 5.4 3.2e-82 276.5 5.4 1.9 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EEB09264.1 - 1.2e-36 124.6 0.8 1.5e-30 105.0 0.0 5.5 4 1 1 5 5 5 3 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EEB09264.1 - 1.2e-31 109.3 2.3 4.5e-29 101.0 0.3 3.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EEB09264.1 - 3.3e-27 94.5 0.4 2.5e-24 85.3 0.0 4.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EEB09264.1 - 1.4e-13 50.7 10.0 3.8e-13 49.3 10.0 1.8 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 EEB09264.1 - 0.00028 21.1 5.9 0.001 19.2 5.9 2.0 1 0 0 1 1 1 1 Up-regulated During Septation Pkinase PF00069.25 EEB09265.1 - 5.6e-65 219.3 0.0 7.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09265.1 - 7.4e-44 150.0 0.0 1.1e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEB09265.1 - 1.8e-07 30.3 0.1 1.8e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEB09265.1 - 7.9e-05 22.1 0.0 0.00039 19.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEB09265.1 - 0.00023 20.2 0.2 0.19 10.7 0.0 2.4 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 EEB09265.1 - 0.045 13.1 0.1 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEB09265.1 - 0.2 11.3 0.1 0.48 10.0 0.1 1.6 1 0 0 1 1 1 0 RIO1 family RhoGAP PF00620.27 EEB09266.1 - 2.7e-35 121.4 0.0 4.7e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SPG48 PF14764.6 EEB09266.1 - 0.09 13.3 0.9 2.2 8.8 0.0 2.9 2 1 1 3 3 3 0 AP-5 complex subunit, vesicle trafficking DUF2458 PF10454.9 EEB09267.1 - 1.4e-24 86.7 2.6 4.7e-24 85.0 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2458) RCC1 PF00415.18 EEB09268.1 - 1.4e-67 224.1 3.2 3.3e-11 43.6 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEB09268.1 - 1e-32 111.2 34.6 9.6e-08 31.6 0.5 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 EEB09268.1 - 0.0014 18.6 0.0 2.7 8.1 0.0 3.6 4 0 0 4 4 4 2 Beta-propeller repeat SUKH-3 PF14433.6 EEB09268.1 - 0.0026 18.2 0.6 9.5 6.7 0.0 4.4 5 0 0 5 5 5 1 SUKH-3 immunity protein Hira PF07569.11 EEB09268.1 - 0.0081 15.9 0.1 18 5.0 0.1 3.9 4 0 0 4 4 4 1 TUP1-like enhancer of split Pkinase PF00069.25 EEB09269.1 - 5.3e-38 130.9 0.0 8.6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09269.1 - 1.5e-29 103.0 0.0 2.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB09269.1 - 0.0025 16.8 0.5 0.0073 15.3 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EEB09269.1 - 0.052 12.3 1.7 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 EEB09269.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Arrestin_C PF02752.22 EEB09270.2 - 1e-11 45.4 2.6 1.2e-08 35.5 0.4 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 EEB09270.2 - 0.032 13.4 2.5 2.8 7.0 0.2 3.2 2 1 1 3 3 3 0 Rgp1 Isochorismatase PF00857.20 EEB09271.1 - 6.4e-27 94.8 0.0 7.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Pkinase PF00069.25 EEB09272.2 - 8.5e-75 251.5 0.0 4.9e-74 249.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09272.2 - 2.8e-51 174.3 0.0 7.9e-51 172.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EEB09272.2 - 0.01 15.4 1.9 0.12 11.9 0.2 3.1 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Arm PF00514.23 EEB09272.2 - 0.038 14.0 0.0 0.68 10.1 0.1 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF349 PF03993.12 EEB09272.2 - 0.059 13.7 0.7 0.24 11.7 0.7 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) RICTOR_M PF14666.6 EEB09272.2 - 0.078 12.8 0.1 0.31 10.8 0.1 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain RTTN_N PF14726.6 EEB09272.2 - 0.28 12.0 2.9 0.84 10.5 0.7 3.0 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Fes1 PF08609.10 EEB09272.2 - 4.7 8.2 7.5 0.73 10.8 1.6 2.6 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Pkinase PF00069.25 EEB09273.1 - 7.2e-44 150.1 0.0 1.1e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09273.1 - 4.3e-26 91.8 0.0 7.8e-26 90.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09273.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB09273.1 - 0.00076 18.9 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEB09273.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CBF PF03914.17 EEB09273.1 - 0.082 12.9 2.5 1.2 9.1 0.0 2.7 3 1 0 3 3 3 0 CBF/Mak21 family Septin PF00735.18 EEB09274.2 - 3.6e-84 282.4 0.0 4.6e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Septin Bax1-I PF01027.20 EEB09275.1 - 3.9e-45 154.2 34.8 4.5e-45 154.0 34.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 EEB09275.1 - 0.0012 18.4 22.2 0.0084 15.7 22.2 1.9 1 1 0 1 1 1 1 Bax inhibitor 1 like SAC3_GANP PF03399.16 EEB09276.1 - 2.6e-113 378.3 5.7 2.6e-113 378.3 5.7 1.9 2 1 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EEB09276.1 - 0.0012 18.8 0.0 0.0047 16.9 0.0 2.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Nexin_C PF08628.12 EEB09276.1 - 0.01 16.4 1.4 0.037 14.6 1.4 2.0 1 0 0 1 1 1 0 Sorting nexin C terminal tRNA-synt_1b PF00579.25 EEB09277.1 - 1.2e-69 234.9 0.0 1.5e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EEB09277.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 S4 domain TyrRSs_C PF16714.5 EEB09277.1 - 0.13 12.1 0.0 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain Clat_adaptor_s PF01217.20 EEB09278.1 - 1.5e-12 47.7 0.1 2.1e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S5 PF00333.20 EEB09279.1 - 2.5e-29 101.0 0.9 5.7e-29 99.9 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EEB09279.1 - 6.7e-22 76.7 0.1 1.4e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S10 PF00338.22 EEB09280.1 - 8e-29 99.8 0.7 1.1e-28 99.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 EEB09280.1 - 0.05 12.2 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein AAA PF00004.29 EEB09281.1 - 1.1e-45 155.3 0.0 2.5e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEB09281.1 - 7.9e-11 41.7 0.1 7e-10 38.7 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EEB09281.1 - 8.6e-09 35.5 0.1 2.5e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEB09281.1 - 2.9e-07 30.8 0.0 8.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEB09281.1 - 3.7e-07 30.7 0.2 5e-05 23.8 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EEB09281.1 - 5.2e-06 25.8 0.0 8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EEB09281.1 - 4.6e-05 23.7 0.5 0.0045 17.3 0.5 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EEB09281.1 - 8.1e-05 22.4 0.0 0.00023 20.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEB09281.1 - 0.00033 21.2 0.0 0.00094 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEB09281.1 - 0.00054 19.8 0.0 0.008 16.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EEB09281.1 - 0.00062 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB09281.1 - 0.00068 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_lid_3 PF17862.1 EEB09281.1 - 0.00069 19.4 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 EEB09281.1 - 0.0007 19.2 0.1 0.0027 17.2 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EEB09281.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EEB09281.1 - 0.0018 18.2 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 EEB09281.1 - 0.0026 17.8 0.0 0.0069 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 EEB09281.1 - 0.003 17.5 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EEB09281.1 - 0.0032 17.4 0.0 0.097 12.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 EEB09281.1 - 0.0043 16.5 0.2 0.015 14.7 0.1 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EEB09281.1 - 0.0051 16.1 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 EEB09281.1 - 0.0091 15.4 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 EEB09281.1 - 0.0094 15.7 0.6 0.93 9.2 0.0 3.3 4 0 0 4 4 4 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EEB09281.1 - 0.013 15.3 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EEB09281.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEB09281.1 - 0.018 14.7 0.1 0.042 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EEB09281.1 - 0.034 14.0 0.1 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EEB09281.1 - 0.037 13.8 0.0 0.077 12.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 EEB09281.1 - 0.042 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EEB09281.1 - 0.059 12.2 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase cobW PF02492.19 EEB09281.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EEB09281.1 - 0.079 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EEB09281.1 - 0.091 12.3 0.3 0.43 10.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EEB09281.1 - 0.1 11.9 1.2 1 8.7 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 EEB09281.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EEB09281.1 - 0.14 11.5 2.8 5.9 6.1 0.1 3.0 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 EEB09281.1 - 0.2 10.8 0.6 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain HIP1_clath_bdg PF16515.5 EEB09281.1 - 0.49 11.0 3.2 6.6 7.4 1.8 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L15e PF00827.17 EEB09282.1 - 6e-88 293.6 8.4 7.3e-88 293.3 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 SH3_1 PF00018.28 EEB09283.2 - 1.5e-24 85.3 0.0 6.5e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EEB09283.2 - 1.6e-24 85.5 0.7 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EEB09283.2 - 2.9e-22 78.7 1.5 3.9e-21 75.1 1.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EEB09283.2 - 4.6e-18 64.6 0.0 3.7e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 EEB09283.2 - 7.8e-13 48.1 13.9 1.3e-12 47.4 13.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Lipase_chap PF03280.14 EEB09283.2 - 2.5 8.0 7.5 4.8 7.1 0.1 2.8 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein FliJ PF02050.16 EEB09283.2 - 2.8 8.2 9.4 9.3 6.5 0.1 3.5 2 1 1 3 3 3 0 Flagellar FliJ protein DEAD PF00270.29 EEB09284.1 - 1.5e-35 122.5 1.3 2.1e-35 122.1 0.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09284.1 - 2.4e-26 92.2 0.1 6.5e-26 90.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEB09284.1 - 0.0038 17.0 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEB09284.1 - 0.046 14.0 0.2 0.34 11.2 0.1 2.5 1 1 1 2 2 2 0 AAA domain CMS1 PF14617.6 EEB09284.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.5 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Spermine_synth PF01564.17 EEB09285.1 - 8.2e-75 250.4 0.0 1.6e-74 249.4 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EEB09285.1 - 3.1e-25 87.8 0.0 5.5e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EEB09285.1 - 6.3e-06 26.8 0.0 3.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EEB09285.1 - 0.00052 19.3 0.0 0.0008 18.7 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 EEB09285.1 - 0.00054 20.7 0.1 0.0028 18.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 EEB09285.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EEB09285.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EEB09285.1 - 0.12 11.6 0.3 0.36 10.1 0.2 1.8 1 1 1 2 2 2 0 O-methyltransferase domain CRM1_repeat_2 PF18784.1 EEB09285.1 - 0.16 11.7 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 tRNA-synt_1c PF00749.21 EEB09286.2 - 4e-105 351.2 0.0 6e-105 350.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EEB09286.2 - 3.1e-48 163.8 2.6 7.2e-48 162.6 2.6 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EEB09286.2 - 3.5e-33 114.9 0.2 1.2e-32 113.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EEB09286.2 - 3e-09 37.7 0.2 9.1e-09 36.1 0.2 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 S8_pro-domain PF16470.5 EEB09286.2 - 0.012 16.4 0.0 0.03 15.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase S8 pro-domain Glyco_hydro_72 PF03198.14 EEB09287.1 - 8.7e-140 465.4 6.1 1.1e-139 465.1 6.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DUF1869 PF08956.10 EEB09287.1 - 0.055 13.4 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1869) Glyco_hydro_2_C PF02836.17 EEB09287.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Proteasom_Rpn13 PF04683.13 EEB09288.1 - 7.4e-28 96.9 0.2 1.2e-27 96.3 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EEB09288.1 - 3.3e-22 78.8 0.6 5.7e-22 78.0 0.6 1.4 1 0 0 1 1 1 1 UCH-binding domain Pkinase PF00069.25 EEB09289.1 - 3e-68 230.0 0.0 4.2e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09289.1 - 2.6e-35 122.0 0.0 4.2e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB09289.1 - 3.3e-05 23.0 0.0 5.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEB09289.1 - 8.7e-05 22.6 0.0 0.0038 17.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEB09289.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EEB09289.1 - 0.016 14.8 0.0 0.044 13.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EEB09289.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_KA1 PF16797.5 EEB09289.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Fungal kinase associated-1 domain dUTPase PF00692.19 EEB09290.1 - 1.5e-43 147.5 0.0 1.7e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase mRNA_triPase PF02940.15 EEB09291.1 - 3e-53 180.8 0.1 4.1e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Snf7 PF03357.21 EEB09292.1 - 2.9e-28 98.6 18.9 3.7e-28 98.3 18.9 1.0 1 0 0 1 1 1 1 Snf7 YqaH PF17448.2 EEB09292.1 - 0.08 13.3 1.9 1.4 9.3 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized YqaH-like CNDH2_C PF16858.5 EEB09292.1 - 0.45 10.3 9.0 0.73 9.7 9.0 1.4 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Snapin_Pallidin PF14712.6 EEB09292.1 - 0.88 10.0 9.8 0.18 12.2 5.2 2.2 1 1 1 2 2 2 0 Snapin/Pallidin YlqD PF11068.8 EEB09292.1 - 2.8 8.3 16.9 5.9 7.3 6.0 2.2 1 1 1 2 2 2 0 YlqD protein KOW PF00467.29 EEB09293.1 - 0.00066 19.5 1.8 0.0013 18.6 1.8 1.4 1 0 0 1 1 1 1 KOW motif SBDS PF01172.18 EEB09294.1 - 1.3e-34 118.1 1.0 2.7e-34 117.1 1.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EEB09294.1 - 1.5e-33 115.2 2.7 1.6e-33 115.2 1.1 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain CagE_TrbE_VirB PF03135.14 EEB09294.1 - 0.048 13.8 0.2 0.084 13.0 0.2 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system P2 PF07194.11 EEB09294.1 - 0.12 12.5 0.8 3 8.0 0.3 2.6 2 0 0 2 2 2 0 P2 response regulator binding domain Brix PF04427.18 EEB09295.1 - 1.9e-22 80.3 0.1 3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Brix domain Methyltransf_28 PF02636.17 EEB09295.1 - 0.22 11.1 3.5 4.3 6.9 3.5 2.1 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2572 PF10833.8 EEB09295.1 - 8.5 6.1 7.1 1.8 8.2 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) MRP-L28 PF09812.9 EEB09296.1 - 6.5e-16 58.9 1.3 7.5e-16 58.7 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ribosom_S12_S23 PF00164.25 EEB09297.1 - 4.3e-36 123.0 1.4 5.9e-36 122.6 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Hexokinase_2 PF03727.16 EEB09298.1 - 4.1e-67 226.1 0.0 5.6e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EEB09298.1 - 3.1e-63 213.3 0.0 4.6e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Zn_ribbon_17 PF17120.5 EEB09299.2 - 4.5e-08 32.6 11.9 4.5e-08 32.6 11.9 1.9 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EEB09299.2 - 0.0017 19.1 11.2 0.6 11.1 0.0 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 EEB09299.2 - 0.013 15.8 6.2 0.013 15.8 6.2 2.7 2 0 0 2 2 2 0 Ring finger domain PROCN PF08083.11 EEB09300.1 - 2.7e-233 774.0 6.6 4.9e-233 773.1 6.6 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EEB09300.1 - 1.5e-126 420.7 1.0 3.5e-126 419.5 1.0 1.7 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EEB09300.1 - 2.9e-87 290.6 3.0 1e-86 288.8 3.0 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EEB09300.1 - 1.4e-79 265.4 1.8 2.9e-79 264.3 1.8 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EEB09300.1 - 1.4e-72 242.1 0.1 3.1e-72 240.9 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EEB09300.1 - 2.5e-45 153.4 0.0 6e-45 152.2 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EEB09300.1 - 3.2e-45 152.4 0.0 1e-44 150.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EEB09300.1 - 3.5e-05 23.8 0.0 8.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RasGAP_C PF03836.15 EEB09301.1 - 1.5e-46 158.0 9.1 1.7e-46 157.8 7.0 2.3 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 EEB09301.1 - 2.2e-33 115.8 0.1 2.2e-33 115.8 0.1 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EEB09301.1 - 4.3e-19 66.5 25.5 0.31 11.0 0.0 12.1 12 0 0 12 12 12 10 IQ calmodulin-binding motif CH PF00307.31 EEB09301.1 - 7.8e-18 64.7 0.0 2.9e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Ku_PK_bind PF08785.11 EEB09301.1 - 3.3 7.9 5.1 7 6.8 0.2 3.6 3 0 0 3 3 3 0 Ku C terminal domain like HMG_CoA_synt_C PF08540.10 EEB09302.2 - 1.5e-116 388.9 0.4 1.9e-116 388.6 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EEB09302.2 - 4.7e-85 283.8 1.6 9.9e-85 282.8 0.8 1.9 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF4078 PF13300.6 EEB09303.1 - 1.7e-19 69.9 8.6 1.7e-19 69.9 8.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CENP-B_N PF04218.13 EEB09303.1 - 0.026 14.1 0.0 0.1 12.3 0.0 2.1 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HAD_2 PF13419.6 EEB09304.1 - 2.2e-10 40.9 0.0 1.2e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB09304.1 - 4.7e-08 33.6 0.0 5.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEB09304.1 - 6.3e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ATG11 PF10377.9 EEB09305.1 - 4.7e-32 110.8 0.3 4.7e-32 110.8 0.3 3.2 2 0 0 2 2 2 1 Autophagy-related protein 11 Seryl_tRNA_N PF02403.22 EEB09305.1 - 0.53 10.5 28.0 0.091 13.0 9.2 5.3 5 0 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Rab_bind PF16704.5 EEB09305.1 - 1.6 8.8 9.6 3.7 7.6 0.2 4.5 4 0 0 4 4 4 0 Rab binding domain DUF4094 PF13334.6 EEB09305.1 - 2.9 8.4 7.5 2.2 8.8 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1765 PF08578.10 EEB09306.1 - 6.7e-29 100.9 4.4 1.3e-28 100.0 4.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SH3_1 PF00018.28 EEB09307.1 - 1.2e-11 44.0 0.0 2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB09307.1 - 3e-10 39.8 0.0 6.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB09307.1 - 1.1e-07 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 EEB09307.1 - 0.00041 20.6 0.2 0.00079 19.7 0.2 1.5 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sugar_tr PF00083.24 EEB09308.1 - 4e-113 378.6 25.6 4.8e-113 378.4 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB09308.1 - 4e-30 105.0 25.1 4e-30 105.0 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEB09308.1 - 2.1e-08 33.1 2.9 2.1e-08 33.1 2.9 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TFIID_NTD2 PF04494.15 EEB09308.1 - 0.093 13.0 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain Pkinase PF00069.25 EEB09309.1 - 4.1e-57 193.5 0.0 5.8e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09309.1 - 3.1e-32 111.9 0.0 5.8e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09309.1 - 2.4e-07 30.4 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEB09309.1 - 1.9e-05 24.7 0.3 0.00037 20.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEB09309.1 - 0.029 13.2 0.0 0.073 11.8 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EEB09309.1 - 0.029 13.3 0.0 0.029 13.3 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EEB09309.1 - 0.033 13.6 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEB09309.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HEAT PF02985.22 EEB09310.1 - 4.8e-05 23.3 9.4 0.69 10.3 0.0 7.8 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EEB09310.1 - 0.00015 22.1 2.6 0.011 16.1 0.2 4.6 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 EEB09310.1 - 0.004 17.6 4.8 3.1 8.4 0.1 5.1 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EEB09310.1 - 0.037 14.6 3.1 25 5.6 0.1 4.8 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EEB09310.1 - 0.08 13.1 2.4 7.4 6.8 0.0 4.4 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 NUC130_3NT PF08158.12 EEB09310.1 - 0.83 10.0 3.8 2.8 8.3 0.1 3.6 3 0 0 3 3 3 0 NUC130/3NT domain CLTH PF10607.9 EEB09310.1 - 1.2 9.0 7.2 0.52 10.2 3.8 2.1 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Ras PF00071.22 EEB09311.1 - 7.8e-53 178.4 0.0 9.1e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB09311.1 - 2.9e-19 69.4 0.0 4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB09311.1 - 3.3e-07 29.9 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB09311.1 - 0.057 13.0 0.0 0.35 10.4 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 EEB09311.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial HSP70 PF00012.20 EEB09312.1 - 2.4e-169 564.4 0.8 2.5e-169 564.3 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEB09312.1 - 1.5e-10 40.5 0.2 1.6e-09 37.1 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 EEB09312.1 - 0.0011 19.4 0.1 0.51 10.8 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA PilM_2 PF11104.8 EEB09312.1 - 0.0084 15.2 0.0 0.55 9.2 0.0 2.6 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; FHA PF00498.26 EEB09313.1 - 0.00027 21.2 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEB09313.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain V-SNARE_C PF12352.8 EEB09314.1 - 2.1e-14 53.6 2.3 2.5e-14 53.3 0.6 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EEB09314.1 - 7e-07 29.1 1.8 5e-06 26.3 0.1 2.4 2 1 0 2 2 2 1 Sec20 Med9 PF07544.13 EEB09314.1 - 0.016 15.3 0.4 0.038 14.1 0.4 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Snapin_Pallidin PF14712.6 EEB09314.1 - 0.019 15.4 2.3 0.021 15.2 0.8 1.8 2 0 0 2 2 2 0 Snapin/Pallidin PilJ PF13675.6 EEB09314.1 - 0.12 12.4 4.1 0.79 9.8 4.1 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CorA PF01544.18 EEB09314.1 - 0.14 11.5 2.1 0.28 10.5 2.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fmp27_WPPW PF10359.9 EEB09314.1 - 0.24 10.2 5.4 0.33 9.8 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2203 PF09969.9 EEB09314.1 - 0.3 11.8 3.4 14 6.4 3.4 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3008 PF11450.8 EEB09314.1 - 1.7 8.9 5.8 0.75 10.0 2.3 2.2 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Peptidase_M48 PF01435.18 EEB09315.1 - 1.4e-33 116.3 0.1 3e-33 115.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M48 Tmemb_14 PF03647.13 EEB09316.1 - 7.8e-19 68.2 8.0 9.5e-19 67.9 8.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EEB09316.1 - 0.089 13.1 1.7 0.12 12.7 0.4 1.9 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 19 Phytochelatin PF05023.14 EEB09317.1 - 2.4e-88 294.9 0.0 6.6e-88 293.5 0.0 1.7 2 0 0 2 2 2 1 Phytochelatin synthase Clathrin_lg_ch PF01086.17 EEB09318.2 - 1e-56 192.6 15.7 1.3e-56 192.2 15.7 1.1 1 0 0 1 1 1 1 Clathrin light chain Neur_chan_memb PF02932.16 EEB09318.2 - 0.097 12.7 3.6 0.13 12.3 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-K PF11802.8 EEB09318.2 - 0.92 9.0 6.9 0.21 11.1 3.9 1.5 2 0 0 2 2 2 0 Centromere-associated protein K Atg14 PF10186.9 EEB09318.2 - 2.1 7.3 7.7 3.1 6.8 7.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRF PF01765.19 EEB09318.2 - 4 7.4 8.6 1.4 8.8 6.0 1.6 2 0 0 2 2 2 0 Ribosome recycling factor R3H-assoc PF13902.6 EEB09318.2 - 9.4 6.6 11.3 37 4.7 11.3 2.0 1 1 0 1 1 1 0 R3H-associated N-terminal domain CDC37_N PF03234.14 EEB09319.1 - 9.8e-41 139.7 6.2 9.8e-41 139.7 6.2 3.0 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EEB09319.1 - 2.4e-33 114.6 0.1 7.9e-33 112.9 0.1 1.9 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EEB09319.1 - 3.4e-26 91.3 0.3 3.4e-26 91.3 0.3 3.1 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF5523 PF17661.1 EEB09319.1 - 0.001 18.8 6.5 0.002 17.8 6.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5523) E2F_CC-MB PF16421.5 EEB09319.1 - 0.011 16.0 2.9 0.03 14.7 0.3 2.8 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain DUF4200 PF13863.6 EEB09319.1 - 0.068 13.6 11.1 0.44 10.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) P16-Arc PF04699.14 EEB09319.1 - 0.48 10.9 10.7 0.67 10.4 0.1 3.4 2 1 1 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) T2SSF PF00482.23 EEB09319.1 - 0.68 9.9 6.3 3.1 7.7 1.2 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F LMBR1 PF04791.16 EEB09319.1 - 3 6.6 3.7 5.4 5.8 3.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Exo_endo_phos PF03372.23 EEB09320.1 - 7e-26 91.2 0.0 9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lin-8 PF03353.15 EEB09320.1 - 0.044 13.4 0.2 0.067 12.8 0.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apc13p PF05839.11 EEB09321.1 - 2.8e-17 62.7 0.3 5e-17 61.9 0.3 1.4 1 0 0 1 1 1 1 Apc13p protein KH_1 PF00013.29 EEB09322.1 - 5.6e-07 29.3 0.2 0.21 11.5 0.0 4.9 5 0 0 5 5 5 2 KH domain Ig_mannosidase PF17753.1 EEB09322.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Ig-fold domain RhoGAP PF00620.27 EEB09323.1 - 7.1e-43 146.0 0.0 1.6e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEB09323.1 - 3.1e-16 59.3 18.7 6.8e-08 32.6 5.2 2.5 2 0 0 2 2 2 2 LIM domain CENP-H PF05837.12 EEB09323.1 - 0.037 14.4 4.0 0.079 13.4 4.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 EEB09323.1 - 0.053 14.0 1.5 0.15 12.6 1.5 1.7 1 0 0 1 1 1 0 Cell division protein ZapB ATG16 PF08614.11 EEB09323.1 - 0.42 10.8 8.5 0.071 13.3 4.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Siva PF05458.12 EEB09323.1 - 0.76 9.4 10.4 1.7 8.3 10.4 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) BRE1 PF08647.11 EEB09323.1 - 1.1 9.3 4.1 1.7 8.8 1.2 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fer4_18 PF13746.6 EEB09323.1 - 9.8 6.4 14.2 0.85 9.8 1.1 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain RRM_1 PF00076.22 EEB09325.1 - 3.8e-08 33.0 0.1 0.00014 21.6 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Host_attach PF10116.9 EEB09325.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.7 3 1 1 4 4 4 0 Protein required for attachment to host cells CDC45 PF02724.14 EEB09325.1 - 7.3 4.7 16.0 0.13 10.5 6.4 2.0 2 0 0 2 2 2 0 CDC45-like protein GPI-anchored PF10342.9 EEB09326.1 - 1.2e-09 38.8 8.8 1.2e-09 38.8 8.8 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.17 EEB09326.1 - 0.028 14.3 6.9 0.18 11.6 6.9 2.4 1 1 0 1 1 1 0 Tissue factor Ribonuclease_3 PF00636.26 EEB09327.1 - 1.1e-21 77.5 0.4 5.2e-21 75.3 0.2 2.3 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEB09327.1 - 7e-18 65.0 0.1 7e-18 65.0 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 EEB09327.1 - 1.7e-08 35.1 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif GRAB PF10375.9 EEB09328.1 - 2.3e-07 30.4 0.2 6.2e-07 29.1 0.2 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Jnk-SapK_ap_N PF09744.9 EEB09328.1 - 0.00025 21.3 16.2 0.00025 21.3 16.2 3.9 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EEB09328.1 - 0.018 15.1 5.4 0.018 15.1 5.4 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EEB09328.1 - 0.044 11.8 24.1 0.062 11.3 24.1 1.3 1 0 0 1 1 1 0 Prominin Filament PF00038.21 EEB09328.1 - 0.59 9.7 48.3 0.31 10.6 9.3 3.2 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 EEB09328.1 - 0.87 9.6 15.8 0.36 10.9 3.5 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 EEB09328.1 - 3.2 5.8 57.2 0.43 8.7 27.0 2.5 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 EEB09328.1 - 3.2 7.1 55.5 0.12 11.7 13.5 3.9 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 EEB09328.1 - 3.8 7.5 51.2 0.24 11.4 6.3 3.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion MAD PF05557.13 EEB09328.1 - 9.4 4.5 58.8 10 4.3 33.1 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Nop PF01798.18 EEB09329.1 - 1.6e-69 233.9 3.5 3.2e-69 232.9 0.0 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EEB09329.1 - 4.1e-43 147.1 0.4 4.1e-43 147.1 0.4 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain Phasin PF05597.11 EEB09329.1 - 2.1 8.4 6.7 0.47 10.5 2.0 2.3 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Rad52_Rad22 PF04098.15 EEB09330.1 - 7.4e-57 191.6 0.0 1e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ATP_bind_1 PF03029.17 EEB09331.1 - 4.9e-79 265.5 2.6 5.5e-79 265.4 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EEB09331.1 - 1.2e-06 28.2 0.4 6e-05 22.7 0.4 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EEB09331.1 - 2.7e-05 23.7 0.0 0.063 12.7 0.0 3.3 2 1 0 2 2 2 1 ADP-ribosylation factor family MeaB PF03308.16 EEB09331.1 - 4.4e-05 22.6 0.0 0.18 10.8 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EEB09331.1 - 8.9e-05 22.2 0.0 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 EEB09331.1 - 0.00011 21.9 0.0 0.0023 17.5 0.0 2.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EEB09331.1 - 0.00017 21.4 0.0 0.00079 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB09331.1 - 0.00024 21.6 0.0 0.00071 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 EEB09331.1 - 0.00024 20.8 0.0 0.057 13.0 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 EEB09331.1 - 0.00024 21.4 0.0 0.0029 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EEB09331.1 - 0.0007 18.9 0.6 0.0013 18.0 0.0 1.7 2 0 0 2 2 1 1 NB-ARC domain AAA_18 PF13238.6 EEB09331.1 - 0.00085 19.9 1.3 0.0031 18.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 EEB09331.1 - 0.00091 18.8 0.0 0.048 13.2 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 EEB09331.1 - 0.0012 18.7 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain G-alpha PF00503.20 EEB09331.1 - 0.0019 17.4 5.6 0.013 14.6 0.0 3.1 3 1 0 4 4 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EEB09331.1 - 0.0021 18.1 0.0 0.061 13.4 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EEB09331.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEB09331.1 - 0.0024 18.0 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EEB09331.1 - 0.0043 17.6 11.1 0.87 10.1 8.1 2.7 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 EEB09331.1 - 0.0061 16.5 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 NTPase KAP_NTPase PF07693.14 EEB09331.1 - 0.0067 15.7 0.0 0.52 9.5 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain Roc PF08477.13 EEB09331.1 - 0.0069 16.6 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EEB09331.1 - 0.0076 16.2 0.1 4.3 7.2 0.0 3.5 4 0 0 4 4 4 0 RsgA GTPase Zeta_toxin PF06414.12 EEB09331.1 - 0.0094 15.2 0.0 0.023 14.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 EEB09331.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 EEB09331.1 - 0.013 15.0 0.0 0.072 12.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 EEB09331.1 - 0.014 15.3 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EEB09331.1 - 0.016 14.9 0.1 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 EEB09331.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CLP1_P PF16575.5 EEB09331.1 - 0.018 14.8 0.1 0.48 10.2 0.0 2.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EEB09331.1 - 0.019 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 EEB09331.1 - 0.02 14.9 0.1 0.089 12.8 0.0 2.1 2 1 1 3 3 2 0 AAA domain AAA_19 PF13245.6 EEB09331.1 - 0.025 14.9 0.0 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEB09331.1 - 0.028 13.8 0.1 0.09 12.1 0.0 1.8 1 1 0 2 2 2 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 EEB09331.1 - 0.034 14.1 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 1 0 Microtubule binding T2SSE PF00437.20 EEB09331.1 - 0.047 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Uteroglobin PF01099.17 EEB09331.1 - 0.061 13.7 0.4 0.26 11.7 0.4 2.1 1 0 0 1 1 1 0 Uteroglobin family AAA_5 PF07728.14 EEB09331.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EEB09331.1 - 0.068 13.6 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EEB09331.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 EEB09331.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 EEB09331.1 - 0.16 12.0 1.4 1.9 8.5 0.0 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain GrpE PF01025.19 EEB09331.1 - 1.2 8.8 10.9 5.5 6.6 8.3 2.2 1 1 1 2 2 2 0 GrpE Dynamin_N PF00350.23 EEB09331.1 - 4.3 7.4 10.0 2.1 8.4 0.4 3.7 1 1 1 2 2 2 0 Dynamin family DUF2347 PF09804.9 EEB09332.2 - 4.8e-35 121.5 0.1 3.3e-25 89.3 0.0 2.7 1 1 2 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EEB09332.2 - 0.00071 19.5 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis M16C_assoc PF08367.11 EEB09333.1 - 1.7e-64 217.4 1.0 2.6e-64 216.8 1.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EEB09333.1 - 1.2e-32 113.4 0.2 1.2e-24 87.3 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEB09333.1 - 2e-05 24.6 0.0 5.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ribosomal_L38e PF01781.18 EEB09334.2 - 1e-33 115.2 2.0 1.1e-33 115.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.7 EEB09335.1 - 9.1e-20 71.7 0.0 1.2e-19 71.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEB09335.1 - 1.7e-06 27.7 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB09335.1 - 0.00084 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EEB09335.1 - 0.0013 18.6 0.0 0.0029 17.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EEB09335.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FmiP_Thoc5 PF09766.9 EEB09336.1 - 1.5e-17 64.0 14.1 1.9e-17 63.6 14.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 EEB09336.1 - 0.0028 17.7 1.7 1.8 8.6 0.1 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) DUF5082 PF16888.5 EEB09336.1 - 0.11 12.7 5.5 0.29 11.4 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Acetyltransf_11 PF13720.6 EEB09336.1 - 0.63 10.6 2.4 19 5.8 0.4 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 IFP_35_N PF07334.13 EEB09336.1 - 0.65 10.1 10.2 0.82 9.8 0.1 3.7 2 2 3 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus UPF0449 PF15136.6 EEB09336.1 - 4.2 7.9 7.5 0.91 10.0 0.8 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 APG6_N PF17675.1 EEB09336.1 - 4.9 7.7 18.0 0.79 10.3 4.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2130 PF09903.9 EEB09337.1 - 3.8e-05 23.1 9.5 5.2e-05 22.6 9.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) Filament PF00038.21 EEB09337.1 - 0.0046 16.6 9.9 0.0055 16.3 9.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF632 PF04782.12 EEB09337.1 - 0.024 14.0 5.0 0.026 13.8 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Aha1_N PF09229.11 EEB09337.1 - 0.026 14.7 2.4 0.026 14.7 2.4 1.6 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Herpes_UL6 PF01763.16 EEB09337.1 - 0.11 10.9 4.3 0.13 10.7 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Prominin PF05478.11 EEB09337.1 - 0.13 10.2 6.3 0.15 10.0 6.3 1.0 1 0 0 1 1 1 0 Prominin DUF1465 PF07323.12 EEB09337.1 - 0.19 11.6 5.8 0.43 10.4 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Enkurin PF13864.6 EEB09337.1 - 0.3 11.5 12.1 0.45 11.0 12.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding MSC PF09402.10 EEB09337.1 - 0.4 10.1 5.0 0.45 9.9 5.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Allexi_40kDa PF05549.11 EEB09337.1 - 0.52 9.8 4.1 0.6 9.6 4.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein HSCB_C PF07743.13 EEB09337.1 - 1.1 9.8 12.6 2.2e+03 -0.8 12.6 2.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Exonuc_VII_L PF02601.15 EEB09337.1 - 1.6 8.2 6.9 1.9 8.0 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EEB09337.1 - 3 6.8 10.6 5.6 6.0 10.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Adhesin_P1_N PF18652.1 EEB09337.1 - 3.9 7.6 6.6 1.5 8.9 2.5 2.1 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain XhlA PF10779.9 EEB09337.1 - 6.8 7.0 9.6 0.47 10.7 0.8 2.2 1 1 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 EEB09337.1 - 8.6 5.5 11.7 5 6.3 3.8 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF883 PF05957.13 EEB09337.1 - 8.9 7.0 8.0 2.7 8.7 1.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PI3_PI4_kinase PF00454.27 EEB09338.1 - 1.6e-41 142.8 0.0 2.5e-39 135.6 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EEB09338.1 - 2.9e-19 69.2 0.3 1.1e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EEB09338.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) UCH PF00443.29 EEB09339.1 - 7.1e-29 101.1 0.6 1.3e-28 100.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEB09339.1 - 6.9e-11 42.3 0.8 6.9e-11 42.3 0.8 2.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EEB09339.1 - 2.1 7.9 6.5 1.5 8.3 2.2 2.6 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PITH PF06201.13 EEB09340.2 - 2.3e-37 128.6 0.1 3.7e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EEB09340.2 - 3.9e-24 84.6 0.1 6.8e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EEB09340.2 - 6.3e-08 32.3 0.1 9.5e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EEB09340.2 - 1.4e-05 25.5 0.2 5.2e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEB09340.2 - 3.8e-05 23.9 0.0 9.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EEB09340.2 - 8.6e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EEB09340.2 - 0.002 18.3 0.4 0.0038 17.4 0.4 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EEB09340.2 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EEB09340.2 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_5 PF13743.6 EEB09340.2 - 0.069 12.8 0.1 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 EEB09340.2 - 0.096 12.5 0.1 0.2 11.4 0.1 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 EEB09340.2 - 0.13 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE WD40 PF00400.32 EEB09341.1 - 6.3e-26 90.1 19.3 6.5e-07 30.0 0.2 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09341.1 - 6.8e-11 42.3 0.2 0.032 14.5 0.0 5.4 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB09341.1 - 0.0074 16.2 0.0 0.23 11.3 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEB09341.1 - 0.039 12.6 1.3 2.8 6.5 0.0 2.9 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Proteasome PF00227.26 EEB09342.1 - 3.2e-23 82.2 0.0 3.8e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2513 PF10711.9 EEB09342.1 - 0.044 14.1 0.3 1.8 8.9 0.0 2.5 2 1 0 3 3 3 0 Hypothetical protein (DUF2513) DUF3074 PF11274.8 EEB09343.1 - 2.1e-16 60.5 0.0 2.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Diphthami_syn_2 PF01902.17 EEB09344.1 - 1.3e-45 155.6 0.0 2.7e-45 154.6 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EEB09344.1 - 8.3e-19 67.8 0.1 1.7e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP QueC PF06508.13 EEB09344.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EEB09344.1 - 0.09 12.3 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Syja_N PF02383.18 EEB09345.1 - 2.1e-35 122.6 0.5 4e-35 121.6 0.5 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EEB09345.1 - 2.9e-08 33.5 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ODC_AZ PF02100.17 EEB09346.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme SHNi-TPR PF10516.9 EEB09347.1 - 6.2e-15 54.4 4.0 1.2e-14 53.4 2.1 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EEB09347.1 - 2.4e-05 24.5 10.5 0.16 12.3 2.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PrlF_antitoxin PF15937.5 EEB09347.1 - 0.024 15.1 0.1 0.065 13.7 0.1 1.7 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin TPR_2 PF07719.17 EEB09347.1 - 0.062 13.4 10.4 1.6 9.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat H-kinase_dim PF02895.14 EEB09347.1 - 0.071 13.5 5.9 0.75 10.2 4.3 3.0 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SesA PF17107.5 EEB09347.1 - 0.26 11.5 4.6 0.4 10.9 1.1 2.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_1 PF00515.28 EEB09347.1 - 0.73 9.8 4.1 32 4.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1151 PF06625.11 EEB09347.1 - 2.6 8.0 10.4 0.62 10.0 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) TPR_11 PF13414.6 EEB09347.1 - 3.6 7.3 5.9 40 4.0 0.3 3.3 3 0 0 3 3 3 0 TPR repeat RabGAP-TBC PF00566.18 EEB09348.1 - 1e-52 178.9 0.2 1.6e-52 178.3 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Macoilin PF09726.9 EEB09348.1 - 0.56 8.7 7.2 0.78 8.2 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Asn_synthase PF00733.21 EEB09349.1 - 1.9e-96 323.8 0.7 3.3e-56 191.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EEB09349.1 - 2e-39 134.3 0.0 3.3e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEB09349.1 - 2.8e-32 111.7 0.0 6.2e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEB09349.1 - 1.9e-08 34.0 0.0 3.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EEB09349.1 - 0.052 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ORMDL PF04061.14 EEB09350.1 - 5.3e-58 194.7 8.0 6.3e-58 194.4 8.0 1.1 1 0 0 1 1 1 1 ORMDL family DUF3278 PF11683.8 EEB09350.1 - 0.027 14.5 0.6 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Pkinase PF00069.25 EEB09351.1 - 9.1e-56 189.1 0.0 7.1e-48 163.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09351.1 - 3.2e-27 95.4 0.0 4.2e-20 72.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EEB09351.1 - 0.024 13.6 0.0 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EEB09351.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EEB09351.1 - 0.096 12.0 0.1 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEB09352.1 - 5.1e-27 94.9 0.0 8.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EEB09352.1 - 2.7e-11 42.7 10.2 0.019 15.2 0.1 6.6 6 0 0 6 6 6 5 HEAT repeat Pkinase_Tyr PF07714.17 EEB09352.1 - 2e-10 40.4 0.0 3.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EEB09352.1 - 9.6e-06 25.9 0.2 0.13 12.7 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EEB09352.1 - 0.0051 16.9 2.6 1.6 8.8 0.1 4.0 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EEB09352.1 - 0.052 14.1 0.0 32 5.2 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat SCO1-SenC PF02630.14 EEB09353.1 - 4.6e-45 152.8 0.0 6.6e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EEB09353.1 - 0.00018 21.4 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EEB09353.1 - 0.0026 18.1 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Trp_oprn_chp PF09534.10 EEB09353.1 - 0.095 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) IATP PF04568.12 EEB09353.1 - 1.5 9.3 4.6 0.31 11.5 1.2 1.7 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SH3_1 PF00018.28 EEB09354.1 - 1.6e-15 56.4 0.0 2.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEB09354.1 - 1.8e-14 53.3 0.0 2.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEB09354.1 - 7.3e-12 44.8 0.0 1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 EEB09354.1 - 0.021 14.9 2.3 0.021 14.9 2.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) LMBR1 PF04791.16 EEB09357.1 - 0.0024 16.9 1.3 0.0037 16.3 1.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein CENP-Q PF13094.6 EEB09357.1 - 0.14 12.4 17.7 0.26 11.5 17.7 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mit_KHE1 PF10173.9 EEB09357.1 - 0.38 10.8 5.1 3.1 7.8 2.6 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Ferlin_C PF16165.5 EEB09357.1 - 1.5 8.8 5.7 0.17 11.8 0.8 1.9 2 0 0 2 2 2 0 Ferlin C-terminus Peptidase_S46 PF10459.9 EEB09357.1 - 1.9 7.0 6.7 2.7 6.5 6.7 1.1 1 0 0 1 1 1 0 Peptidase S46 FAM76 PF16046.5 EEB09357.1 - 7.6 5.8 12.9 0.16 11.3 4.8 2.0 1 1 1 2 2 2 0 FAM76 protein RPAP1_C PF08620.10 EEB09358.1 - 6.9e-26 90.2 0.8 2.3e-25 88.5 0.1 2.1 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EEB09358.1 - 2.4e-13 49.6 3.5 2.4e-13 49.6 3.5 2.4 2 1 0 2 2 2 1 RPAP1-like, N-terminal GDH_N PF12466.8 EEB09358.1 - 0.078 13.2 0.3 0.61 10.3 0.0 2.6 3 1 0 3 3 3 0 Glutamate dehydrogenase N terminal HEAT PF02985.22 EEB09358.1 - 0.13 12.6 0.4 36 5.0 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat Hydin_ADK PF17213.3 EEB09358.1 - 3.1 8.0 7.8 6.9 6.9 7.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain VHS PF00790.19 EEB09359.1 - 0.099 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 VHS domain HUN PF08729.10 EEB09360.1 - 6.7e-09 35.6 0.1 6.7e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain SURF6 PF04935.12 EEB09361.1 - 2.9e-41 141.5 52.1 1e-40 139.7 52.1 1.8 1 1 0 1 1 1 1 Surfeit locus protein 6 NIF3 PF01784.18 EEB09362.1 - 4.9e-69 232.7 0.0 6.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Adaptin_N PF01602.20 EEB09363.1 - 2.8e-121 405.7 17.1 3.3e-121 405.4 17.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEB09363.1 - 9.9e-54 181.7 2.5 9.9e-54 181.7 2.5 3.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEB09363.1 - 8.5e-15 54.9 2.3 6.6e-07 29.6 0.1 5.8 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 EEB09363.1 - 6.4e-08 32.2 9.4 0.055 13.7 0.0 6.7 8 0 0 8 8 8 3 HEAT repeat Cnd3 PF12719.7 EEB09363.1 - 0.00075 18.8 2.2 0.28 10.3 0.0 3.4 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EEB09363.1 - 0.0046 17.4 5.8 0.92 10.1 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat DUF1959 PF09218.10 EEB09363.1 - 0.026 14.6 0.3 0.24 11.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) DUF445 PF04286.12 EEB09363.1 - 0.034 13.9 1.3 0.082 12.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) FANCI_S2 PF14676.6 EEB09363.1 - 0.22 11.8 2.7 15 5.9 0.3 3.8 3 0 0 3 3 3 0 FANCI solenoid 2 V-ATPase_H_C PF11698.8 EEB09363.1 - 0.39 10.8 5.7 1 9.5 0.2 3.2 3 0 0 3 3 3 0 V-ATPase subunit H AAA PF00004.29 EEB09364.2 - 3.9e-38 130.8 0.0 6e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEB09364.2 - 3.4e-09 36.6 0.0 1.6e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EEB09364.2 - 4.9e-09 35.8 0.0 8.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EEB09364.2 - 4.1e-06 26.6 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEB09364.2 - 1e-05 25.8 0.5 0.00046 20.5 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EEB09364.2 - 0.00014 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEB09364.2 - 0.00032 20.9 0.0 0.00067 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEB09364.2 - 0.00043 20.7 0.0 0.00099 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EEB09364.2 - 0.00079 18.7 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EEB09364.2 - 0.00097 19.1 0.1 0.0028 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EEB09364.2 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEB09364.2 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEB09364.2 - 0.0031 16.9 0.1 0.0062 15.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EEB09364.2 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEB09364.2 - 0.0096 16.5 0.0 0.024 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EEB09364.2 - 0.013 15.4 0.0 4.5 7.1 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EEB09364.2 - 0.028 13.6 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EEB09364.2 - 0.058 13.3 0.1 0.14 12.1 0.1 1.7 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 EEB09364.2 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EEB09364.2 - 0.093 12.1 0.0 2.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EEB09364.2 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EEB09364.2 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EEB09364.2 - 0.14 11.7 0.3 0.65 9.5 0.1 2.1 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 EEB09364.2 - 0.15 11.5 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EEB09364.2 - 0.34 10.2 0.3 4.8 6.5 0.1 2.1 1 1 1 2 2 2 0 KaiC HSP20 PF00011.21 EEB09365.1 - 4.9e-24 84.4 0.5 6.4e-24 84.1 0.5 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EEB09365.1 - 1.7e-13 49.9 0.0 2.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EEB09365.1 - 0.0011 20.0 0.0 0.0016 19.4 0.0 1.3 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 EEB09365.1 - 0.0059 17.0 0.0 0.014 15.8 0.0 1.5 1 1 1 2 2 2 1 PIH1 CS-like domain DUF4097 PF13349.6 EEB09365.1 - 0.018 14.4 0.9 0.11 11.8 0.9 1.8 1 1 0 1 1 1 0 Putative adhesin FKBP26_C PF18046.1 EEB09365.1 - 0.027 14.6 0.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal HMA PF00403.26 EEB09365.1 - 0.041 14.3 1.2 0.22 12.0 0.2 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain BON PF04972.17 EEB09365.1 - 0.061 13.7 1.3 0.2 12.0 0.3 2.2 2 1 1 3 3 3 0 BON domain polyprenyl_synt PF00348.17 EEB09366.1 - 2.3e-66 223.5 0.0 3.4e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Coatomer_WDAD PF04053.14 EEB09367.1 - 1.7e-123 412.9 7.6 3.4e-123 412.0 7.6 1.5 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EEB09367.1 - 1.9e-91 306.8 2.2 3e-91 306.2 2.2 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EEB09367.1 - 7.6e-45 150.0 17.5 7.4e-08 32.9 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09367.1 - 7.4e-09 35.8 0.3 0.37 11.1 0.0 6.0 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB09367.1 - 0.0022 16.7 10.2 0.13 10.9 0.2 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 zinc_ribbon_9 PF14369.6 EEB09367.1 - 0.035 14.4 0.1 0.092 13.0 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon Far-17a_AIG1 PF04750.14 EEB09368.2 - 2.8e-32 111.7 16.8 3.3e-32 111.5 16.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_transf_24 PF18404.1 EEB09369.1 - 1.3e-147 490.4 7.4 2.3e-146 486.3 6.6 2.3 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EEB09369.1 - 1.4e-55 189.0 0.5 3.6e-54 184.4 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EEB09369.1 - 5.3e-35 120.3 3.7 1.9e-34 118.5 0.3 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EEB09369.1 - 3.4e-29 101.1 0.0 6.6e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 EEB09369.1 - 1e-19 71.2 0.1 2.7e-19 69.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EEB09369.1 - 1e-13 51.7 0.1 1.4e-10 41.5 0.2 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EEB09369.1 - 5.9e-07 29.3 0.4 1.1e-06 28.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpn3_C PF08375.11 EEB09370.1 - 8.6e-26 90.2 1.5 2.5e-25 88.7 1.5 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EEB09370.1 - 1.2e-19 70.7 0.1 1.6e-18 67.1 0.0 2.8 3 0 0 3 3 3 1 PCI domain UQ_con PF00179.26 EEB09371.1 - 3.9e-53 178.9 0.0 4.3e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEB09371.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EEB09371.1 - 0.027 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EEB09371.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pre-SET PF05033.16 EEB09372.2 - 3.9e-21 75.7 5.7 7e-21 74.9 3.2 2.3 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 EEB09372.2 - 2.3e-19 70.4 0.7 1.2e-18 68.1 0.1 2.3 2 0 0 2 2 2 1 SET domain Chromo PF00385.24 EEB09372.2 - 3e-11 43.1 0.1 3e-11 43.1 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3827 PF12877.7 EEB09372.2 - 1.7 6.9 5.4 2.4 6.4 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PH_6 PF15406.6 EEB09373.1 - 6.4e-37 126.3 1.7 1.7e-36 124.9 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EEB09373.1 - 2.2e-05 24.9 0.3 0.00033 21.1 0.0 2.9 3 1 1 4 4 4 1 PH domain PH_13 PF16652.5 EEB09373.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain RXT2_N PF08595.11 EEB09374.1 - 9.2e-13 48.5 7.6 5e-12 46.1 0.9 2.8 2 1 1 3 3 3 2 RXT2-like, N-terminal CdiI PF07262.11 EEB09374.1 - 0.058 13.2 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 CDI immunity protein Arginosuc_synth PF00764.19 EEB09375.1 - 4.9e-152 506.7 0.0 5.6e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EEB09375.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EEB09375.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Apq12 PF12716.7 EEB09376.1 - 1.8e-08 34.2 13.3 2.6e-08 33.7 13.3 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Hydrolase_3 PF08282.12 EEB09377.1 - 2e-48 165.4 0.0 2.3e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EEB09377.1 - 1.6e-08 34.4 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EEB09377.1 - 6.7e-05 23.3 0.8 0.0013 19.0 0.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEB09377.1 - 0.0047 17.4 0.3 4.1 7.8 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ribosomal_L2 PF00181.23 EEB09377.1 - 0.67 10.0 2.2 6.4 6.8 0.1 2.6 1 1 1 2 2 2 0 Ribosomal Proteins L2, RNA binding domain DIOX_N PF14226.6 EEB09378.1 - 2.9e-26 92.5 0.0 2e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEB09378.1 - 6.6e-19 68.3 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CENP-O PF09496.10 EEB09379.1 - 6.2e-12 46.0 3.4 8.5e-11 42.2 0.2 3.0 3 1 0 3 3 3 1 Cenp-O kinetochore centromere component Isy1 PF06246.12 EEB09379.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Isy1-like splicing family ZapB PF06005.12 EEB09379.1 - 0.093 13.2 1.8 0.2 12.1 1.8 1.6 1 0 0 1 1 1 0 Cell division protein ZapB TYW3 PF02676.14 EEB09380.1 - 9e-53 178.8 0.0 1.1e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 POP1 PF06978.11 EEB09381.1 - 7.1e-58 196.0 9.8 1.2e-57 195.2 9.8 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EEB09381.1 - 2.2e-30 104.9 0.2 5.6e-30 103.5 0.2 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 EEB09381.1 - 7.2e-06 25.5 0.0 0.0088 15.4 0.0 3.0 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain DUF3161 PF11362.8 EEB09381.1 - 0.14 12.1 0.0 0.57 10.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Peptidase_A22B PF04258.13 EEB09382.1 - 6.5e-72 242.4 8.7 4e-63 213.6 2.5 2.0 1 1 1 2 2 2 2 Signal peptide peptidase SPP PF06550.11 EEB09382.1 - 0.011 15.2 19.9 0.14 11.6 17.6 2.4 2 1 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease zf-C2H2 PF00096.26 EEB09383.1 - 3.4e-08 33.5 10.9 0.00011 22.4 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEB09383.1 - 2.6e-06 27.6 11.3 0.00014 22.1 0.2 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEB09383.1 - 0.0028 18.3 9.9 0.25 12.3 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger RRM_3 PF08777.11 EEB09384.1 - 2.7e-06 27.4 0.0 9.6e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 RNA binding motif CPSF73-100_C PF11718.8 EEB09385.2 - 7.3e-61 205.5 5.7 7.3e-61 205.5 5.7 1.6 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EEB09385.2 - 7.2e-32 110.0 0.1 4.5e-31 107.4 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EEB09385.2 - 3.1e-21 75.7 0.0 5e-20 71.8 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB09385.2 - 1.3e-20 74.3 0.2 2.2e-20 73.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EEB09385.2 - 2.6e-15 56.1 0.0 5.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EEB09385.2 - 3.2e-07 30.1 0.2 6.6e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EEB09385.2 - 4.3e-06 26.7 0.2 2.6e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EEB09385.2 - 0.0037 16.5 0.0 0.011 15.0 0.0 1.8 1 0 0 1 1 1 1 Putative beta-lactamase-like family TetR_C_19 PF17924.1 EEB09385.2 - 0.046 14.3 0.4 0.17 12.5 0.2 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mtc PF03820.17 EEB09386.1 - 2.8e-122 407.6 0.1 3.2e-122 407.5 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DEAD PF00270.29 EEB09387.1 - 1.4e-36 125.9 0.1 2.3e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09387.1 - 1.8e-29 102.3 0.1 1.4e-27 96.2 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09387.1 - 3.5e-09 36.9 0.0 7.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EEB09387.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Packaging_FI PF14000.6 EEB09387.1 - 0.056 13.9 1.6 0.11 12.9 1.6 1.4 1 0 0 1 1 1 0 DNA packaging protein FI PEP-utilisers_N PF05524.13 EEB09388.1 - 0.76 10.0 7.1 2.1 8.5 7.1 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal ApbA PF02558.16 EEB09389.2 - 4.3e-08 32.9 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EEB09389.2 - 0.00088 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal COPIIcoated_ERV PF07970.12 EEB09390.1 - 2e-72 243.7 0.0 2.9e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEB09390.1 - 8.1e-30 103.0 0.5 5.1e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Anti-TRAP PF15777.5 EEB09390.1 - 1.2 9.2 5.2 2.4 8.2 5.2 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein MPC PF03650.13 EEB09391.1 - 1.5e-41 141.0 0.2 1.8e-41 140.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 EEB09391.1 - 0.083 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Sel1 PF08238.12 EEB09392.1 - 4.9e-46 154.1 10.9 1.7e-08 34.9 0.7 7.9 8 0 0 8 8 8 7 Sel1 repeat YL1 PF05764.13 EEB09393.1 - 9.5e-35 120.9 31.8 1.1e-34 120.6 31.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 EEB09393.1 - 1.9e-10 40.3 0.1 3.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GREB1 PF15782.5 EEB09393.1 - 0.57 7.2 11.3 0.68 7.0 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 EEB09394.1 - 5.5e-63 212.8 0.0 1.7e-62 211.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09394.1 - 8.6e-30 103.9 0.1 1.7e-21 76.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EEB09394.1 - 1.4e-07 32.1 0.3 3.1e-07 31.0 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 EEB09394.1 - 0.0085 16.0 4.3 0.18 11.7 0.1 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEB09394.1 - 0.0087 15.0 0.0 0.019 13.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EEB09394.1 - 0.011 15.0 0.4 0.08 12.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EEB09394.1 - 0.023 14.1 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 EEB09395.1 - 4.4e-42 144.1 1.7 5.1e-42 143.9 1.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Membralin PF09746.9 EEB09395.1 - 0.087 11.9 1.4 0.097 11.7 0.9 1.3 1 1 0 1 1 1 0 Tumour-associated protein DUF5320 PF17253.2 EEB09395.1 - 0.11 13.6 0.0 0.15 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Spc24 PF08286.11 EEB09395.1 - 0.11 12.8 1.9 0.19 12.0 1.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DNA_pol3_a_NII PF11490.8 EEB09395.1 - 0.31 11.0 4.0 0.82 9.6 2.4 2.3 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA PF00004.29 EEB09396.2 - 1.2e-91 304.0 0.1 3.7e-45 153.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB09396.2 - 4.2e-22 77.7 0.6 7.3e-10 38.5 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EEB09396.2 - 2.8e-15 56.4 0.0 9.9e-08 31.9 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEB09396.2 - 7.9e-13 49.1 1.4 0.00013 22.4 0.1 4.4 3 2 1 4 4 2 2 AAA ATPase domain AAA_22 PF13401.6 EEB09396.2 - 6.2e-12 46.0 0.2 0.0012 19.2 0.0 4.9 3 2 1 4 4 3 2 AAA domain AAA_33 PF13671.6 EEB09396.2 - 1.7e-11 44.4 0.0 2.4e-05 24.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EEB09396.2 - 1.1e-10 41.9 0.0 0.0002 21.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEB09396.2 - 1.3e-10 41.4 0.2 0.0015 18.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EEB09396.2 - 6.9e-10 39.6 0.0 2.1e-05 25.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 EEB09396.2 - 4.3e-09 36.0 0.3 9e-05 21.8 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 EEB09396.2 - 9.3e-09 35.6 0.0 0.0017 18.7 0.0 3.4 3 1 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 EEB09396.2 - 2.4e-08 34.1 0.0 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EEB09396.2 - 1.4e-07 31.9 0.0 0.0028 17.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EEB09396.2 - 1.8e-07 30.7 0.6 0.0087 15.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EEB09396.2 - 1.9e-07 31.0 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 EEB09396.2 - 6.4e-07 29.3 0.0 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEB09396.2 - 9.4e-07 28.7 0.2 0.0018 18.2 0.0 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 EEB09396.2 - 1.1e-06 28.7 0.1 0.01 15.8 0.0 3.0 3 0 0 3 3 3 2 NACHT domain Rad17 PF03215.15 EEB09396.2 - 2e-06 27.8 0.1 0.01 15.8 0.0 2.8 2 1 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 EEB09396.2 - 2.2e-06 27.1 0.0 0.077 12.3 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 EEB09396.2 - 4.9e-06 26.2 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 EEB09396.2 - 5.6e-06 26.6 0.0 0.00062 19.9 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 EEB09396.2 - 7.6e-06 26.5 0.0 0.29 11.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 EEB09396.2 - 8.2e-06 25.8 0.0 0.034 14.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EEB09396.2 - 8.9e-06 26.2 0.0 0.025 15.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEB09396.2 - 9.2e-06 25.0 0.0 0.057 12.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEB09396.2 - 2.3e-05 24.1 4.7 0.46 10.0 0.0 4.5 4 1 0 5 5 5 2 AAA domain ATPase PF06745.13 EEB09396.2 - 2.8e-05 23.6 0.0 0.44 9.9 0.0 3.4 3 0 0 3 3 3 2 KaiC NB-ARC PF00931.22 EEB09396.2 - 5.8e-05 22.4 0.0 0.8 8.8 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain Sigma54_activat PF00158.26 EEB09396.2 - 9.2e-05 22.2 0.0 0.25 11.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.22 EEB09396.2 - 0.00014 22.0 0.6 0.18 11.9 0.0 3.4 4 0 0 4 4 2 1 Shikimate kinase Viral_helicase1 PF01443.18 EEB09396.2 - 0.00018 21.3 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EEB09396.2 - 0.00038 20.6 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EEB09396.2 - 0.00047 20.1 0.0 1.8 8.4 0.0 2.9 2 1 1 3 3 2 2 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EEB09396.2 - 0.0005 19.9 0.6 0.8 9.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EEB09396.2 - 0.00051 19.2 0.1 0.69 8.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EEB09396.2 - 0.00058 19.6 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EEB09396.2 - 0.0027 17.1 0.0 11 5.4 0.0 3.6 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 EEB09396.2 - 0.0029 17.1 0.1 2.4 7.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AFG1_ATPase PF03969.16 EEB09396.2 - 0.0033 16.4 0.0 0.49 9.2 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase ATP-synt_ab PF00006.25 EEB09396.2 - 0.006 16.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 EEB09396.2 - 0.0074 16.2 0.0 4.8 7.1 0.0 2.9 2 1 0 2 2 2 0 NTPase SRPRB PF09439.10 EEB09396.2 - 0.011 15.2 0.0 2.7 7.4 0.0 3.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CPT PF07931.12 EEB09396.2 - 0.013 15.4 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EEB09396.2 - 0.013 15.2 0.0 2 8.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 EEB09396.2 - 0.021 14.6 0.0 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 EEB09396.2 - 0.023 14.5 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.16 EEB09396.2 - 0.033 13.6 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase PAP1 PF08601.10 EEB09396.2 - 0.035 13.8 0.6 0.063 13.0 0.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2075 PF09848.9 EEB09396.2 - 0.037 13.3 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Hydin_ADK PF17213.3 EEB09396.2 - 0.051 13.9 3.1 0.76 10.0 0.0 3.3 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain ResIII PF04851.15 EEB09396.2 - 0.069 13.1 0.0 31 4.5 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ADK PF00406.22 EEB09396.2 - 0.082 13.0 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase Guanylate_kin PF00625.21 EEB09396.2 - 0.094 12.4 0.0 12 5.6 0.0 3.5 2 1 1 3 3 3 0 Guanylate kinase AAA_30 PF13604.6 EEB09396.2 - 0.097 12.4 0.1 16 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EEB09396.2 - 0.1 12.9 4.2 15 5.9 0.1 3.6 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EEB09396.2 - 0.1 12.7 0.1 8.3 6.5 0.0 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase HECT PF00632.25 EEB09397.1 - 3e-99 332.4 0.0 4e-99 332.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EEB09397.1 - 3.1e-36 123.1 17.0 1.4e-12 47.5 1.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EEB09397.1 - 1.1e-19 70.6 0.1 2.7e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 EEB09398.1 - 2.5e-16 59.2 0.0 4.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.15 EEB09398.1 - 0.012 15.3 7.9 0.018 14.8 7.9 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4201 PF13870.6 EEB09398.1 - 0.013 15.2 1.3 0.016 14.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GAS PF13851.6 EEB09398.1 - 0.018 14.4 3.3 0.023 14.0 3.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EEB09398.1 - 0.039 12.8 3.3 0.049 12.5 3.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EEB09398.1 - 0.039 14.4 2.6 0.15 12.6 2.6 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EEB09398.1 - 0.17 12.6 1.5 0.2 12.3 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 EEB09398.1 - 0.27 11.3 3.5 0.32 11.1 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 EEB09398.1 - 0.38 8.6 0.9 0.42 8.5 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 EEB09398.1 - 0.42 10.9 2.3 0.59 10.4 2.3 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 EEB09398.1 - 0.49 11.3 6.0 0.68 10.9 6.0 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 EEB09398.1 - 0.57 10.7 10.2 0.81 10.2 10.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 EEB09398.1 - 0.63 9.6 7.6 0.85 9.2 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Coa1 PF08695.10 EEB09400.1 - 1.5e-26 92.4 0.0 2.7e-26 91.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Pex14_N PF04695.13 EEB09400.1 - 0.018 15.7 4.1 0.026 15.2 4.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CUE PF02845.16 EEB09401.2 - 1.4e-06 27.9 0.0 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 2 CUE domain Hap4_Hap_bind PF10297.9 EEB09402.1 - 5.2e-06 26.4 5.8 5.2e-06 26.4 5.8 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF3450 PF11932.8 EEB09402.1 - 0.054 12.8 0.5 0.089 12.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FMO-like PF00743.19 EEB09403.1 - 1.5e-35 122.6 0.0 1.2e-18 66.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEB09403.1 - 1.6e-15 57.2 0.0 8.3e-10 38.4 0.1 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEB09403.1 - 9.2e-12 45.2 0.0 1e-09 38.6 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EEB09403.1 - 8.2e-08 32.2 0.0 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEB09403.1 - 1.9e-07 30.6 0.0 1.3e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEB09403.1 - 3.3e-07 30.4 0.0 7.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEB09403.1 - 8.4e-07 28.4 1.1 4.2e-05 22.9 0.1 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EEB09403.1 - 0.00014 21.2 0.0 0.0003 20.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 EEB09403.1 - 0.00082 18.9 0.0 0.0098 15.4 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Amino_oxidase PF01593.24 EEB09403.1 - 0.004 16.5 0.0 0.097 11.9 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EEB09403.1 - 0.018 13.8 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EEB09403.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EEB09403.1 - 0.039 14.0 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Adap_comp_sub PF00928.21 EEB09404.1 - 7e-93 310.8 0.1 9.2e-93 310.4 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEB09404.1 - 3.7e-06 26.9 0.6 6.8e-06 26.1 0.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 EEB09405.1 - 0.00011 22.0 2.5 0.00011 22.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB09405.1 - 0.08 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif Ank_4 PF13637.6 EEB09406.1 - 2.5e-29 101.2 5.9 6.3e-15 55.3 0.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEB09406.1 - 6.4e-21 74.7 2.0 3.7e-19 69.1 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEB09406.1 - 2.5e-17 61.2 0.5 8.5e-08 31.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EEB09406.1 - 3.6e-17 62.2 1.7 5.9e-09 36.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EEB09406.1 - 1e-16 60.5 2.4 3.5e-08 33.5 0.4 2.8 3 0 0 3 3 3 2 Ankyrin repeat RPN7 PF10602.9 EEB09406.1 - 0.069 12.9 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 UQ_con PF00179.26 EEB09407.1 - 1.1e-50 170.9 0.0 1.3e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAT PF02259.23 EEB09408.1 - 2e-62 211.4 9.8 2e-62 211.4 9.8 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EEB09408.1 - 3.5e-33 115.4 0.4 8.1e-33 114.3 0.4 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EEB09408.1 - 5.8e-07 29.2 0.5 1.8e-06 27.7 0.5 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 EEB09408.1 - 0.0097 16.0 0.3 14 6.1 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2070 PF09843.9 EEB09409.1 - 0.086 11.1 7.1 0.087 11.1 7.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyclin_C_2 PF16899.5 EEB09410.1 - 1.2e-17 64.2 6.4 6.2e-16 58.7 0.9 3.2 3 1 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EEB09410.1 - 2e-08 34.1 0.1 6.4e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEB09410.1 - 0.002 18.2 0.8 0.0053 16.8 0.3 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain ARA70 PF12489.8 EEB09410.1 - 0.089 13.0 2.6 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Nuclear coactivator TFIIB PF00382.19 EEB09410.1 - 0.12 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat SAE2 PF08573.10 EEB09410.1 - 2.7 9.2 7.0 1.1 10.4 1.6 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus WD40 PF00400.32 EEB09411.1 - 0.00032 21.4 0.3 0.26 12.2 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09411.1 - 0.012 15.9 0.0 2.7 8.3 0.0 3.3 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain K1 PF02960.14 EEB09411.1 - 0.023 14.8 0.2 0.05 13.7 0.2 1.5 1 0 0 1 1 1 0 K1 glycoprotein Man-6-P_recep PF02157.15 EEB09411.1 - 0.12 11.5 0.8 0.24 10.5 0.1 1.7 2 0 0 2 2 2 0 Mannose-6-phosphate receptor Na_H_Exchanger PF00999.21 EEB09412.1 - 5.7e-69 232.7 39.5 2.2e-37 128.8 16.5 2.4 2 1 1 3 3 3 2 Sodium/hydrogen exchanger family Sedlin_N PF04628.13 EEB09414.2 - 4.4e-16 59.2 1.1 4.9e-16 59.1 1.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-UBR PF02207.20 EEB09415.2 - 4.2e-21 74.9 8.5 1.1e-20 73.5 8.5 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EEB09415.2 - 1.5e-05 24.7 0.0 4.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SUR7 PF06687.12 EEB09416.1 - 3.9e-13 49.5 20.8 3.7e-11 43.1 20.8 2.0 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 EEB09416.1 - 0.002 18.1 12.6 0.002 18.1 12.6 2.0 1 1 1 2 2 2 1 Membrane-associating domain Pex24p PF06398.11 EEB09416.1 - 1.8 7.5 4.2 2.2 7.2 4.2 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PLDc_N PF13396.6 EEB09416.1 - 3.9 7.5 10.5 0.6 10.1 1.1 3.4 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal CH PF00307.31 EEB09417.2 - 1.1e-50 170.4 0.1 5.2e-25 87.7 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EEB09417.2 - 9.1e-10 38.2 0.0 2.1e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.10 EEB09417.2 - 7.6e-08 32.3 0.6 1e-06 28.7 0.0 3.2 3 1 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 EEB09417.2 - 1.2e-05 24.8 0.2 0.00017 21.3 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EEB09417.2 - 0.00092 18.6 0.0 0.00092 18.6 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EEB09417.2 - 0.0077 16.7 0.3 0.0077 16.7 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EEB09417.2 - 0.066 12.7 0.0 0.33 10.5 0.0 2.3 1 0 0 1 1 1 0 EF hand DUF4065 PF13274.6 EEB09417.2 - 0.26 12.2 2.0 0.59 11.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Streptin-Immun PF11083.8 EEB09417.2 - 0.56 10.6 5.2 19 5.8 0.5 3.8 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein FNIP_M PF14637.6 EEB09417.2 - 1.7 8.6 4.9 4.1 7.4 0.4 2.6 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Pkinase PF00069.25 EEB09418.2 - 1.7e-08 34.2 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09418.2 - 1.9e-07 30.6 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EEB09418.2 - 0.0013 18.8 0.1 0.91 10.0 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat RIX1 PF08167.12 EEB09418.2 - 0.0045 16.7 0.5 0.93 9.2 0.0 3.0 1 1 1 2 2 2 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EEB09418.2 - 0.0096 16.3 0.0 3.5 8.1 0.0 3.4 2 1 1 3 3 3 1 HEAT repeats IL2 PF00715.17 EEB09418.2 - 0.086 12.8 1.6 12 5.9 0.2 2.4 1 1 1 2 2 2 0 Interleukin 2 HEAT_EZ PF13513.6 EEB09418.2 - 0.2 12.2 0.1 29 5.3 0.0 2.9 2 1 0 2 2 2 0 HEAT-like repeat Shugoshin_N PF07558.11 EEB09419.2 - 2.1e-13 49.9 12.2 4.5e-13 48.8 12.2 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EEB09419.2 - 6.5e-08 32.2 3.0 6.5e-08 32.2 3.0 3.2 4 0 0 4 4 4 1 Shugoshin C terminus Mod_r PF07200.13 EEB09419.2 - 8.8e-05 22.6 5.3 8.8e-05 22.6 5.3 2.4 3 1 0 3 3 3 1 Modifier of rudimentary (Mod(r)) protein DUF1087 PF06465.13 EEB09419.2 - 0.45 10.6 3.9 2.3 8.3 3.9 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1087) AIP3 PF03915.13 EEB09420.1 - 1e-96 324.5 19.0 1.9e-96 323.6 19.0 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Prefoldin_2 PF01920.20 EEB09420.1 - 1.6 8.7 11.6 2.9 7.9 2.6 3.4 2 1 0 2 2 2 0 Prefoldin subunit CHDCT2 PF08074.11 EEB09420.1 - 3 8.0 7.9 0.22 11.7 0.7 2.8 3 1 0 3 3 3 0 CHDCT2 (NUC038) domain Baculo_PEP_C PF04513.12 EEB09420.1 - 3.8 7.6 15.5 1.7 8.6 2.8 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1761 PF08570.10 EEB09421.1 - 4e-22 78.8 2.9 4.6e-22 78.6 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L44 PF00935.19 EEB09422.1 - 1.8e-34 118.1 11.4 2.5e-34 117.6 11.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 EEB09422.1 - 0.14 12.6 6.9 0.66 10.5 1.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L33 Thymidylat_synt PF00303.19 EEB09423.1 - 3.6e-112 373.9 0.0 3.2e-111 370.8 0.0 2.0 2 0 0 2 2 2 1 Thymidylate synthase Flavoprotein PF02441.19 EEB09423.1 - 9.3e-52 174.9 0.1 1.5e-51 174.3 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein TFIIF_alpha PF05793.12 EEB09423.1 - 0.42 9.1 2.7 0.62 8.6 2.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CTP_transf_like PF01467.26 EEB09424.1 - 8.9e-30 103.8 0.0 7.1e-23 81.4 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like Metallophos_2 PF12850.7 EEB09425.2 - 1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TTC5_OB PF16669.5 EEB09425.2 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Acetyltransf_1 PF00583.25 EEB09427.1 - 3.6e-10 40.1 0.0 4.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB09427.1 - 1.9e-07 31.0 0.1 2.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB09427.1 - 6.3e-05 23.3 0.1 9.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB09427.1 - 0.007 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EEB09427.1 - 0.019 14.5 0.8 0.035 13.6 0.1 1.8 1 1 1 2 2 2 0 Putative acetyl-transferase Glutaredoxin PF00462.24 EEB09428.1 - 1.3e-16 60.5 0.1 2e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EEB09428.1 - 0.00084 19.8 0.3 0.0015 19.0 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EEB09428.1 - 0.0041 17.5 0.0 0.0055 17.1 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EEB09428.1 - 0.0045 16.8 0.2 0.0085 15.9 0.2 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DUF4752 PF15944.5 EEB09428.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) PI31_Prot_C PF08577.11 EEB09429.1 - 1e-09 39.4 9.5 1e-09 39.4 9.5 2.5 2 1 1 3 3 3 1 PI31 proteasome regulator GMP_synt_C PF00958.22 EEB09430.2 - 3.7e-41 139.1 0.0 7.7e-41 138.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EEB09430.2 - 2.5e-37 128.5 0.0 4.3e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EEB09430.2 - 4.4e-07 29.3 0.0 0.00017 20.8 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EEB09430.2 - 1.5e-05 24.9 0.0 3.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.19 EEB09430.2 - 0.0002 20.8 0.1 0.00032 20.1 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 EEB09430.2 - 0.00064 18.6 0.1 0.0018 17.1 0.0 1.8 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EEB09430.2 - 0.0017 17.9 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EEB09430.2 - 0.022 14.4 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 EEB09430.2 - 0.041 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 PP-loop family HOASN PF14515.6 EEB09430.2 - 0.046 14.1 0.1 0.11 12.9 0.1 1.6 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices MetJ PF01340.20 EEB09430.2 - 0.093 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ IF3_N PF05198.16 EEB09431.1 - 0.00071 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EEB09431.1 - 0.03 14.3 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain AA_permease PF00324.21 EEB09433.1 - 2.5e-141 471.5 26.7 2.9e-141 471.4 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB09433.1 - 2.4e-39 135.4 34.8 3.4e-39 134.9 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF805 PF05656.14 EEB09433.1 - 0.022 15.2 10.4 0.19 12.1 2.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF805) CCAP PF11105.8 EEB09433.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a SAPS PF04499.15 EEB09434.1 - 4.3e-170 566.7 4.7 4.3e-170 566.7 4.7 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.17 EEB09435.1 - 2.7e-44 150.7 0.0 4.6e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EEB09435.1 - 9.9e-17 60.8 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EEB09435.1 - 9.7e-10 38.2 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3507 PF12015.8 EEB09435.1 - 0.035 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) YjeF_N PF03853.15 EEB09436.1 - 7.4e-25 87.8 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EEB09436.1 - 2.9e-08 34.5 15.3 1.8e-07 31.9 15.3 2.2 1 1 0 1 1 1 1 FDF domain Hfq PF17209.3 EEB09436.1 - 2.7e-06 26.9 0.0 6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Hfq protein SM-ATX PF14438.6 EEB09436.1 - 0.0039 17.3 0.0 0.015 15.4 0.0 2.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 EEB09436.1 - 0.023 14.4 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 LSM domain Peptidase_M16_C PF05193.21 EEB09437.1 - 2.1e-36 125.7 0.0 3.4e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEB09437.1 - 3e-27 95.4 0.0 7e-27 94.2 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.14 EEB09437.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Methyltransf_11 PF08241.12 EEB09438.1 - 7.7e-24 84.2 0.0 1.2e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB09438.1 - 1.3e-20 73.9 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB09438.1 - 6e-19 68.5 0.0 9.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB09438.1 - 1.6e-16 60.4 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB09438.1 - 1.6e-15 57.6 0.0 2.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEB09438.1 - 1.5e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EEB09438.1 - 3.1e-09 36.6 0.0 4.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EEB09438.1 - 1.1e-08 34.7 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EEB09438.1 - 1.2e-05 25.4 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEB09438.1 - 1.9e-05 23.7 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EEB09438.1 - 2.2e-05 24.1 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EEB09438.1 - 2.7e-05 23.9 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EEB09438.1 - 3.2e-05 23.6 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EEB09438.1 - 0.00028 20.8 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EEB09438.1 - 0.00036 19.7 0.0 0.00048 19.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TPMT PF05724.11 EEB09438.1 - 0.00079 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 EEB09438.1 - 0.00093 18.7 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 EEB09438.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EEB09438.1 - 0.0041 16.9 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_10 PF05971.12 EEB09438.1 - 0.061 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_15 PF09445.10 EEB09438.1 - 0.067 12.8 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Snf7 PF03357.21 EEB09439.2 - 1.5e-44 151.7 20.2 1.7e-44 151.5 20.2 1.1 1 0 0 1 1 1 1 Snf7 Methyltransf_22 PF13383.6 EEB09439.2 - 0.16 11.5 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Endotoxin_N PF03945.14 EEB09439.2 - 0.28 10.9 5.5 0.44 10.2 5.4 1.4 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain NPV_P10 PF05531.12 EEB09439.2 - 0.43 11.1 19.2 0.15 12.5 4.6 3.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 EEB09439.2 - 1.7 8.1 9.1 2.4 7.6 5.7 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Osmo_CC PF08946.10 EEB09439.2 - 2.3 8.5 9.3 0.63 10.3 0.1 3.3 3 1 0 3 3 3 0 Osmosensory transporter coiled coil Uso1_p115_C PF04871.13 EEB09439.2 - 2.3 8.6 24.7 0.43 10.9 5.0 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 EEB09439.2 - 5.1 7.6 29.0 3.9e+02 1.5 0.1 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region ENTH PF01417.20 EEB09440.1 - 3.3e-48 162.8 0.1 5.2e-48 162.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EEB09440.1 - 4e-27 94.4 177.2 1.8e+04 -11.1 28.7 8.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) ANTH PF07651.16 EEB09440.1 - 0.00024 20.2 0.1 0.00074 18.6 0.0 1.7 1 1 1 2 2 2 1 ANTH domain DUF3432 PF11914.8 EEB09440.1 - 0.00034 20.8 0.6 5.2 7.4 0.1 3.5 1 1 2 3 3 3 3 Domain of unknown function (DUF3432) UIM PF02809.20 EEB09440.1 - 0.5 10.4 10.5 0.044 13.7 2.1 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif TPR_MLP1_2 PF07926.12 EEB09441.1 - 1.5e-24 86.5 23.1 1.5e-24 86.5 23.1 19.6 6 5 11 20 20 20 8 TPR/MLP1/MLP2-like protein ERM PF00769.19 EEB09441.1 - 0.00018 21.4 42.4 0.00018 21.4 42.4 12.3 1 1 8 12 12 12 2 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 EEB09441.1 - 0.0038 17.4 13.4 0.0038 17.4 13.4 17.2 5 4 6 14 14 14 4 Tropomyosin like CEP63 PF17045.5 EEB09441.1 - 0.0056 16.6 39.1 0.0056 16.6 39.1 11.2 3 3 6 10 10 10 2 Centrosomal protein of 63 kDa Med31 PF05669.12 EEB09442.1 - 1.4e-36 124.4 6.1 1.7e-36 124.1 6.1 1.0 1 0 0 1 1 1 1 SOH1 NT-C2 PF10358.9 EEB09443.1 - 2.3e-26 92.3 1.1 3.1e-26 91.9 1.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2428 PF10350.9 EEB09444.1 - 1.7e-61 207.9 0.0 2.9e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DEAD PF00270.29 EEB09445.1 - 3e-37 128.1 0.2 4.8e-37 127.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09445.1 - 5.8e-32 110.3 0.2 2.7e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09445.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EutH PF04346.12 EEB09445.1 - 0.0044 16.3 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH UCH PF00443.29 EEB09446.1 - 5.9e-75 252.1 0.0 1.2e-74 251.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EEB09446.1 - 1.3e-16 61.0 2.0 2e-16 60.4 0.1 2.5 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 EEB09446.1 - 2.7e-13 50.2 6.3 2.2e-05 24.2 0.9 3.7 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Antimicrobial_7 PF08102.11 EEB09446.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Zn-ribbon_8 PF09723.10 EEB09446.1 - 0.11 12.7 3.5 3.3 7.9 1.9 2.7 2 0 0 2 2 2 0 Zinc ribbon domain UN_NPL4 PF11543.8 EEB09446.1 - 7.2 7.2 5.3 3.3 8.3 0.1 2.9 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 PDH PF02153.17 EEB09447.2 - 6.1e-15 54.9 0.0 8.4e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EEB09447.2 - 7e-07 29.5 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEB09447.2 - 1.3e-06 28.9 0.0 3.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EEB09447.2 - 0.0004 19.8 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EEB09447.2 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EEB09447.2 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EEB09447.2 - 0.0089 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EEB09447.2 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.9 EEB09447.2 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain V-ATPase_H_N PF03224.14 EEB09448.1 - 8e-06 25.4 2.1 0.0001 21.7 2.1 2.3 1 1 0 1 1 1 1 V-ATPase subunit H RICTOR_M PF14666.6 EEB09448.1 - 0.00014 21.6 0.4 0.19 11.5 0.1 3.1 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain UNC45-central PF11701.8 EEB09448.1 - 0.0035 17.3 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central SLED PF12140.8 EEB09448.1 - 0.029 14.9 1.4 0.077 13.5 0.5 2.2 2 0 0 2 2 2 0 SLED domain TFIID-18kDa PF02269.16 EEB09449.1 - 3.8e-26 90.9 0.1 4.3e-26 90.7 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EEB09449.1 - 0.048 13.7 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EEB09449.1 - 0.088 13.1 0.1 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 EEB09450.1 - 5.4e-49 166.9 0.0 7.1e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09450.1 - 1.2e-29 103.4 0.0 1.9e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09450.1 - 8.8e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB09450.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAC3_GANP PF03399.16 EEB09451.1 - 9e-95 317.4 4.4 9e-95 317.4 4.4 1.4 2 0 0 2 2 2 1 SAC3/GANP family DUF5549 PF17703.1 EEB09451.1 - 0.48 10.1 4.6 0.78 9.4 4.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Thymidylate_kin PF02223.17 EEB09452.1 - 2.7e-50 170.6 0.0 3.1e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EEB09452.1 - 0.0007 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EEB09452.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 EEB09452.1 - 0.035 14.3 0.0 0.054 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EEB09452.1 - 0.043 13.3 0.0 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Methyltransf_11 PF08241.12 EEB09453.1 - 2.1e-20 73.2 0.0 3.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEB09453.1 - 4.8e-18 65.6 0.0 8.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEB09453.1 - 4.1e-17 62.4 0.0 5.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB09453.1 - 1.6e-12 48.0 0.0 3.7e-12 46.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEB09453.1 - 3.3e-12 46.6 0.0 6.9e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEB09453.1 - 2.8e-08 33.6 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EEB09453.1 - 4.1e-08 32.9 0.0 6.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EEB09453.1 - 8.7e-08 31.8 0.1 1.8e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EEB09453.1 - 1.4e-07 31.1 0.1 2.6e-07 30.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 EEB09453.1 - 2.9e-07 29.9 0.0 4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EEB09453.1 - 2.2e-06 27.6 0.0 3.4e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EEB09453.1 - 9.4e-06 25.7 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EEB09453.1 - 4.3e-05 22.3 0.0 5.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EEB09453.1 - 4.5e-05 23.2 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 EEB09453.1 - 5e-05 23.1 0.0 0.00026 20.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 EEB09453.1 - 7.5e-05 22.3 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EEB09453.1 - 0.00022 20.4 0.0 0.0004 19.6 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.11 EEB09453.1 - 0.00023 20.2 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 EEB09453.1 - 0.00046 19.4 0.1 0.045 12.9 0.1 2.1 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_18 PF12847.7 EEB09453.1 - 0.0023 17.9 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EEB09453.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 TehB PF03848.14 EEB09453.1 - 0.0088 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 EEB09453.1 - 0.027 13.8 0.1 0.94 8.7 0.0 2.8 3 1 1 4 4 4 0 O-methyltransferase domain FtsJ PF01728.19 EEB09453.1 - 0.033 14.3 0.1 0.096 12.8 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EEB09453.1 - 0.068 12.6 0.0 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 EEB09453.1 - 0.099 12.3 0.1 1.2 8.8 0.1 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2406 PF10295.9 EEB09454.1 - 1.8e-13 50.9 0.1 8.4e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Aldo_ket_red PF00248.21 EEB09455.1 - 2.3e-42 145.2 0.0 3.6e-40 138.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ANAPC5 PF12862.7 EEB09456.1 - 7.7e-35 118.9 4.9 4.1e-34 116.5 4.9 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 EEB09456.1 - 0.002 17.6 4.8 0.14 11.5 0.2 2.3 2 0 0 2 2 2 2 MalT-like TPR region UBX PF00789.20 EEB09457.1 - 1.3e-13 50.9 0.0 2.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Ribosomal_S4e PF00900.20 EEB09458.1 - 4.6e-38 129.0 0.5 8.9e-38 128.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EEB09458.1 - 3.3e-26 90.7 0.0 6e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EEB09458.1 - 5.2e-20 71.3 7.7 1.1e-19 70.2 7.7 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EEB09458.1 - 8.2e-08 31.8 0.3 1.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EEB09458.1 - 2.5e-06 27.2 2.5 7e-06 25.8 1.1 2.5 2 0 0 2 2 2 1 KOW motif Abhydrolase_1 PF00561.20 EEB09459.1 - 1.7e-06 27.9 0.0 0.00023 20.9 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEB09459.1 - 0.00044 20.9 0.0 0.017 15.7 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEB09459.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EEB09459.1 - 0.084 12.4 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase HU-HIG PF18291.1 EEB09459.1 - 0.19 11.9 0.1 0.43 10.7 0.0 1.5 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Ribonuc_red_lgC PF02867.15 EEB09460.2 - 5.8e-188 625.7 0.0 7.7e-188 625.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EEB09460.2 - 6.1e-24 83.8 0.0 1.9e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EEB09460.2 - 8.2e-16 58.4 0.0 2.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Troponin-I_N PF11636.8 EEB09460.2 - 0.87 9.6 5.6 0.92 9.5 3.5 2.1 2 0 0 2 2 2 0 Troponin I residues 1-32 Ras PF00071.22 EEB09461.1 - 1.1e-56 190.9 0.0 1.3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB09461.1 - 4.8e-22 78.4 0.0 7.1e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB09461.1 - 2.5e-07 30.3 0.0 3.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEB09461.1 - 9.4e-05 22.0 0.1 0.00024 20.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEB09461.1 - 0.00067 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EEB09461.1 - 0.071 12.9 0.1 22 4.8 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EEB09461.1 - 0.083 12.8 0.2 0.35 10.8 0.1 2.0 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EEB09461.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TRP PF06011.12 EEB09462.1 - 3.1e-99 332.6 33.9 4.1e-99 332.2 33.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEB09462.1 - 1e-34 119.9 1.3 1.5e-34 119.3 1.3 1.3 1 0 0 1 1 1 1 ML-like domain DEAD PF00270.29 EEB09463.1 - 3.6e-48 163.7 0.0 7e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09463.1 - 5.3e-23 81.5 0.0 3.7e-22 78.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEB09463.1 - 2.9e-20 72.2 0.4 5.6e-20 71.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEB09463.1 - 0.00021 21.3 0.2 0.00047 20.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4554 PF15091.6 EEB09463.1 - 0.5 9.2 4.5 0.75 8.6 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SH2_2 PF14633.6 EEB09464.1 - 4.2e-85 284.5 0.3 1.4e-84 282.9 0.1 2.0 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 EEB09464.1 - 3.2e-45 152.7 0.0 6.7e-45 151.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EEB09464.1 - 1.2e-43 148.5 0.0 3.2e-43 147.1 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EEB09464.1 - 3.8e-34 117.6 0.9 1.6e-33 115.6 0.6 2.3 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EEB09464.1 - 6.8e-22 77.9 19.3 6.8e-22 77.9 19.3 4.2 3 1 1 4 4 4 1 Acidic N-terminal SPT6 S1 PF00575.23 EEB09464.1 - 3.1e-06 27.4 0.0 9e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 EEB09464.1 - 2e-05 24.7 0.0 7.6e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif SH2 PF00017.24 EEB09464.1 - 2.7e-05 24.2 0.1 0.00018 21.5 0.0 2.6 3 0 0 3 3 3 1 SH2 domain Tex_YqgF PF16921.5 EEB09464.1 - 0.00019 21.9 0.0 0.00045 20.7 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 EEB09464.1 - 0.00033 21.5 1.2 0.003 18.4 1.2 2.9 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 EEB09464.1 - 0.0029 17.3 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 Tex-like protein N-terminal domain MRC1 PF09444.10 EEB09465.1 - 3.7e-29 102.1 10.3 3.7e-29 102.1 10.3 4.4 4 1 1 5 5 5 1 MRC1-like domain Ribosomal_S25 PF03297.15 EEB09466.1 - 8e-35 119.1 2.9 8.7e-35 119.0 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein TerB_C PF15615.6 EEB09466.1 - 0.069 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 TerB-C domain PaaX PF07848.12 EEB09466.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein AA_permease_2 PF13520.6 EEB09467.1 - 1e-45 156.4 49.1 1.3e-45 156.1 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEB09467.1 - 7.6e-24 84.1 41.4 1.1e-23 83.7 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease T4BSS_DotI_IcmL PF11393.8 EEB09467.1 - 0.089 12.3 0.2 0.73 9.3 0.0 2.3 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component DJ-1_PfpI PF01965.24 EEB09468.2 - 8.5e-13 48.4 0.0 1.9e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EEB09468.2 - 5.9e-09 35.9 0.1 5.2e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like FTR1 PF03239.14 EEB09469.1 - 4.8e-96 321.6 11.6 5.9e-96 321.2 11.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2615 PF11027.8 EEB09469.1 - 0.02 15.0 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Ferric_reduct PF01794.19 EEB09469.1 - 0.046 13.9 0.9 0.046 13.9 0.9 2.3 2 0 0 2 2 2 0 Ferric reductase like transmembrane component YajC PF02699.15 EEB09469.1 - 0.048 13.5 0.2 20 5.1 0.0 3.0 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4381 PF14316.6 EEB09469.1 - 0.74 10.0 4.1 6.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4079 PF13301.6 EEB09469.1 - 1.8 8.7 5.8 14 5.8 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Ctr PF04145.15 EEB09469.1 - 5.9 7.5 6.1 2.1e+02 2.5 0.0 3.2 2 1 0 2 2 2 0 Ctr copper transporter family Cu-oxidase PF00394.22 EEB09470.1 - 4.3e-40 137.4 7.1 1.8e-39 135.4 0.3 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEB09470.1 - 2.4e-39 134.2 11.3 2.2e-36 124.6 1.4 3.6 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EEB09470.1 - 6.7e-36 122.9 3.7 8.9e-35 119.3 1.6 3.0 3 0 0 3 3 3 1 Multicopper oxidase Aminotran_1_2 PF00155.21 EEB09471.1 - 9.1e-23 81.0 0.0 1.1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II cobW PF02492.19 EEB09472.1 - 3.1e-34 118.1 0.0 4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EEB09472.1 - 0.00064 18.8 0.8 0.0094 15.0 0.8 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zip PF02535.22 EEB09472.1 - 0.0027 17.0 2.9 0.0029 16.9 2.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Pox_A32 PF04665.12 EEB09472.1 - 0.0027 17.2 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein MMR_HSR1 PF01926.23 EEB09472.1 - 0.0085 16.2 0.0 0.025 14.6 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEB09472.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EEB09472.1 - 0.019 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EEB09472.1 - 0.067 12.4 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 EEB09472.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NicO PF03824.16 EEB09472.1 - 2.3 7.5 10.0 3.1 7.1 10.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Methyltransf_4 PF02390.17 EEB09473.1 - 9.5e-55 184.7 0.0 1.4e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EEB09473.1 - 0.00014 22.5 0.0 0.00046 20.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EEB09473.1 - 0.00019 21.0 0.0 0.001 18.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEB09473.1 - 0.00079 19.4 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEB09473.1 - 0.0051 17.5 0.0 0.017 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEB09473.1 - 0.029 15.0 0.0 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EEB09473.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AICARFT_IMPCHas PF01808.18 EEB09474.1 - 3.3e-90 302.5 0.0 5.3e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EEB09474.1 - 1.3e-24 86.2 0.0 2.5e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain zf-CCCH PF00642.24 EEB09475.1 - 4.9e-19 67.7 21.5 2.5e-11 43.2 4.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEB09475.1 - 3.3e-08 33.3 29.3 2.6e-07 30.4 7.3 2.6 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EEB09475.1 - 3.3e-07 29.9 19.4 3.9e-06 26.5 3.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEB09475.1 - 0.0014 19.0 2.3 0.0014 19.0 2.3 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EEB09475.1 - 1.4 9.6 11.5 1.3 9.7 0.9 2.3 1 1 1 2 2 2 0 Torus domain SHR3_chaperone PF08229.11 EEB09476.2 - 4.5e-28 97.5 0.6 9.8e-28 96.4 0.6 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 TrbH PF07283.11 EEB09477.2 - 0.0048 17.1 0.1 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Conjugal transfer protein TrbH PSP1 PF04468.12 EEB09478.2 - 3.1e-32 110.7 1.1 6.6e-32 109.6 1.1 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NUC173 PF08161.12 EEB09479.1 - 7.8e-17 61.6 5.9 1.7e-09 37.7 0.0 5.2 4 1 1 5 5 5 2 NUC173 domain HEAT PF02985.22 EEB09479.1 - 0.0055 16.9 0.0 13 6.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EEB09479.1 - 0.36 10.9 4.5 1.1 9.2 0.1 3.7 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Parvo_coat PF00740.18 EEB09479.1 - 0.59 8.7 4.9 0.88 8.1 4.9 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 HMGL-like PF00682.19 EEB09480.2 - 4e-82 275.7 0.2 6.2e-82 275.1 0.2 1.3 1 0 0 1 1 1 1 HMGL-like DUF2624 PF11116.8 EEB09480.2 - 0.16 12.8 0.1 5.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Ribosomal_L16 PF00252.18 EEB09481.1 - 6.3e-34 116.8 0.1 7.9e-34 116.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SKN1 PF03935.15 EEB09482.1 - 1.2e-09 37.1 0.0 1.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) REGB_T4 PF10715.9 EEB09482.1 - 0.054 13.7 0.0 0.072 13.3 0.0 1.2 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB Sensor PF13796.6 EEB09482.1 - 0.3 11.1 3.3 0.44 10.6 3.3 1.2 1 0 0 1 1 1 0 Putative sensor TMEM223 PF14640.6 EEB09483.1 - 8.1e-06 26.1 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 223 Invas_SpaK PF03519.14 EEB09483.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Invasion protein B family AAA PF00004.29 EEB09484.1 - 4.6e-46 156.5 0.0 1e-42 145.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEB09484.1 - 2.7e-11 43.1 0.0 7.8e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEB09484.1 - 3.4e-07 30.8 0.1 5.7e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EEB09484.1 - 6.1e-07 29.3 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EEB09484.1 - 4.6e-06 26.9 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEB09484.1 - 0.00027 21.0 0.5 0.0021 18.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EEB09484.1 - 0.00047 20.5 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Bromodomain PF00439.25 EEB09484.1 - 0.0046 17.0 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 1 1 Bromodomain ABC_tran PF00005.27 EEB09484.1 - 0.0047 17.4 0.2 0.077 13.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 EEB09484.1 - 0.0099 16.0 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEB09484.1 - 0.0099 15.8 0.2 0.043 13.7 0.2 2.2 1 1 0 1 1 1 1 NACHT domain PhoH PF02562.16 EEB09484.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EEB09484.1 - 0.018 14.6 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEB09484.1 - 0.022 15.0 3.3 0.26 11.6 0.5 3.2 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 EEB09484.1 - 0.033 13.4 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EEB09484.1 - 0.033 13.6 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EEB09484.1 - 0.036 13.3 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EEB09484.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EEB09484.1 - 0.04 14.5 0.0 0.18 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEB09484.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 EEB09484.1 - 0.057 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EEB09484.1 - 0.08 12.7 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EEB09484.1 - 0.092 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEB09484.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.9 5 1 0 5 5 4 0 AAA domain AAA_23 PF13476.6 EEB09484.1 - 2.8 8.4 0.0 2.8 8.4 0.0 4.0 5 1 0 5 5 3 0 AAA domain AAA_18 PF13238.6 EEB09485.2 - 1.4e-07 32.1 0.0 2.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB09485.2 - 0.0065 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 EEB09485.2 - 0.015 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 EEB09485.2 - 0.034 14.7 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EEB09485.2 - 0.035 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEB09485.2 - 0.036 14.2 0.0 0.068 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EEB09485.2 - 0.093 12.5 0.8 0.81 9.4 0.8 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family WD40 PF00400.32 EEB09486.1 - 9.1e-43 143.4 16.8 1.5e-08 35.2 0.7 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09486.1 - 2.2e-06 27.8 0.3 0.11 12.9 0.1 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EEB09486.1 - 0.052 12.3 0.0 1 8.0 0.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EEB09486.1 - 0.17 10.5 4.3 13 4.3 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 S10_plectin PF03501.15 EEB09487.1 - 3.2e-44 148.9 0.1 3.9e-44 148.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain CENP-N PF05238.13 EEB09488.1 - 8.1e-65 219.7 3.0 2.8e-63 214.6 3.0 2.0 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Nuc_sug_transp PF04142.15 EEB09489.2 - 8.4e-84 281.4 7.2 1e-83 281.1 7.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 EEB09489.2 - 4.7e-08 32.4 3.5 5.8e-08 32.1 3.5 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EEB09489.2 - 3.2e-07 29.8 3.8 3.2e-07 29.8 3.8 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EEB09489.2 - 4.4e-07 29.4 5.0 4.4e-07 29.4 5.0 1.6 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EEB09489.2 - 5.3e-07 29.9 13.0 2.2e-06 27.9 1.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EEB09489.2 - 7.5e-05 22.4 2.7 0.00012 21.8 2.7 1.3 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter TPT PF03151.16 EEB09489.2 - 0.00029 20.3 4.0 0.00076 18.9 3.9 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF202 PF02656.15 EEB09489.2 - 0.067 13.6 0.1 0.26 11.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Na_Ca_ex PF01699.24 EEB09490.1 - 1.2e-41 142.2 44.4 8.2e-22 77.8 16.4 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Mad3_BUB1_I PF08311.12 EEB09491.1 - 9e-43 145.2 0.7 1.7e-42 144.3 0.7 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EEB09491.1 - 5.1e-06 26.6 0.3 9.3e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein ALIX_LYPXL_bnd PF13949.6 EEB09491.1 - 0.1 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Sua5_yciO_yrdC PF01300.18 EEB09492.1 - 6.7e-50 169.1 0.0 1.1e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EEB09492.1 - 3.1e-31 108.7 0.0 6.3e-31 107.7 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Syntaxin-18_N PF10496.9 EEB09493.1 - 4.5e-07 30.0 1.1 4.5e-07 30.0 1.1 2.4 2 2 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EEB09493.1 - 2.9e-05 24.0 0.0 8.8e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 SNARE domain Vma12 PF11712.8 EEB09493.1 - 1.5 8.8 4.8 7.6 6.6 0.0 2.5 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KIAA1430 PF13879.6 EEB09493.1 - 2.3 9.0 10.6 0.42 11.4 6.2 2.1 2 0 0 2 2 2 0 KIAA1430 homologue Arg_decarbox_C PF17944.1 EEB09493.1 - 6.2 7.5 6.3 1.2 9.8 0.3 2.6 2 1 1 3 3 3 0 Arginine decarboxylase C-terminal helical extension FH2 PF02181.23 EEB09494.1 - 1.2e-60 205.6 11.0 1.2e-60 205.6 11.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EEB09494.1 - 3.2e-12 46.4 3.2 3.3e-12 46.3 0.0 2.7 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.12 EEB09494.1 - 5.2e-11 42.5 99.0 9e-11 41.7 99.0 1.3 1 0 0 1 1 1 1 Formin Homology Region 1 Drf_FH3 PF06367.16 EEB09494.1 - 9.6e-06 25.3 0.7 9.6e-06 25.3 0.7 2.8 1 1 1 2 2 2 1 Diaphanous FH3 Domain MoeA_C PF03454.15 EEB09494.1 - 0.018 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) TAF6_C PF07571.13 EEB09494.1 - 0.39 11.1 1.8 2.6 8.4 0.1 3.1 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Trans_reg_C PF00486.28 EEB09494.1 - 5.2 7.2 8.3 3.2 7.9 0.2 4.1 5 0 0 5 5 5 0 Transcriptional regulatory protein, C terminal WD40 PF00400.32 EEB09495.1 - 4.3e-29 100.1 28.2 0.0008 20.2 0.0 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09495.1 - 1.4e-08 34.9 2.9 1.1 9.6 0.0 5.8 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EEB09495.1 - 0.0022 17.4 0.1 0.0061 15.9 0.2 1.7 2 0 0 2 2 2 1 WD40-like domain Med6 PF04934.14 EEB09496.1 - 1.4e-47 160.8 0.3 2.1e-47 160.3 0.3 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MFS_1 PF07690.16 EEB09497.2 - 6.7e-38 130.5 25.3 9.6e-38 130.0 25.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2177 PF09945.9 EEB09497.2 - 0.32 11.1 6.6 0.35 11.0 3.4 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2177) Fungal_trans PF04082.18 EEB09498.2 - 6.2e-19 68.1 1.5 6.2e-19 68.1 1.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB09498.2 - 0.0003 20.9 14.0 0.00055 20.0 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 EEB09498.2 - 0.13 12.8 6.7 0.23 11.9 6.7 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region UPRTase PF14681.6 EEB09499.1 - 3.3e-55 186.8 0.3 2.4e-49 167.6 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEB09499.1 - 1.3e-08 34.6 0.0 3.2e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TagF_N PF09867.9 EEB09499.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated DUF1688 PF07958.11 EEB09500.1 - 1.6e-146 488.4 0.0 1.8e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GTP_CH_N PF12471.8 EEB09501.2 - 1.1e-86 289.6 0.0 1.8e-86 288.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EEB09501.2 - 4.9e-14 52.2 0.0 7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Zn_clus PF00172.18 EEB09502.1 - 0.0046 17.1 7.7 0.0046 17.1 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPRTase PF14681.6 EEB09503.1 - 1.3e-69 233.8 0.0 1.5e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEB09503.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Transp_cyt_pur PF02133.15 EEB09504.1 - 5.5e-167 556.0 40.9 6.4e-167 555.8 40.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 EEB09505.1 - 1e-45 156.2 53.4 1e-45 156.2 53.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB09505.1 - 7.4e-16 57.7 26.0 7.9e-16 57.6 24.9 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB09505.1 - 1.8e-11 43.6 4.5 1.8e-11 43.6 4.5 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2678 PF10856.8 EEB09505.1 - 0.01 15.8 2.5 0.01 15.8 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) VIT1 PF01988.19 EEB09505.1 - 0.056 13.3 14.2 0.62 9.9 4.5 3.8 3 0 0 3 3 3 0 VIT family Neurensin PF14927.6 EEB09505.1 - 0.44 10.2 3.5 0.24 11.1 0.2 2.3 2 1 0 2 2 2 0 Neurensin MFS_1 PF07690.16 EEB09506.2 - 4.2e-39 134.5 42.9 6.8e-37 127.2 42.2 3.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB09506.2 - 2.2e-16 59.4 23.7 3e-16 59.0 23.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB09506.2 - 2.5e-14 53.0 0.6 2.5e-14 53.0 0.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 EEB09506.2 - 0.00025 20.0 4.9 0.00025 20.0 4.9 2.8 3 1 0 3 3 3 1 MFS_1 like family Xan_ur_permease PF00860.20 EEB09507.1 - 6.4e-71 239.1 30.9 8e-69 232.2 30.9 2.1 1 1 0 1 1 1 1 Permease family AA_permease PF00324.21 EEB09508.1 - 7.3e-121 404.1 43.8 8.9e-121 403.8 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEB09508.1 - 2.4e-29 102.4 46.5 3e-29 102.1 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease BC10 PF06726.12 EEB09508.1 - 5.1 7.4 6.8 1.2 9.5 0.5 3.2 3 1 0 3 3 3 0 Bladder cancer-related protein BC10 OCD_Mu_crystall PF02423.15 EEB09509.1 - 1.2e-58 198.6 0.0 1.3e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EEB09509.1 - 2.9e-07 30.6 0.0 5.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EEB09509.1 - 0.0099 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Imm45 PF15572.6 EEB09510.2 - 4.4e-17 62.2 28.8 9 6.8 0.1 17.2 2 2 17 19 19 19 13 Immunity protein 45 Scm3 PF10384.9 EEB09511.1 - 5.7e-17 61.2 0.0 9.3e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 NTF2 PF02136.20 EEB09511.1 - 9.5e-15 55.2 0.0 1.5e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EEB09511.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 UTP15_C PF09384.10 EEB09512.1 - 0.018 14.7 0.2 2 8.1 0.0 2.1 2 0 0 2 2 2 0 UTP15 C terminal ComZ PF10815.8 EEB09512.1 - 0.072 13.1 0.2 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 ComZ DUF4298 PF14131.6 EEB09512.1 - 0.12 12.3 0.5 0.18 11.8 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) CBM_15 PF03426.14 EEB09512.1 - 0.19 11.3 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DIPSY PF11763.8 EEB09513.2 - 7.9e-42 142.3 2.2 7.9e-42 142.3 2.2 2.5 2 0 0 2 2 2 1 Cell-wall adhesin ligand-binding C-terminal Imm45 PF15572.6 EEB09513.2 - 2.9e-15 56.4 22.8 7.5 7.0 0.1 14.2 2 2 14 16 16 16 10 Immunity protein 45 ArfGap PF01412.18 EEB09514.1 - 2.6e-39 133.9 0.1 5e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MFS_1 PF07690.16 EEB09515.1 - 1.3e-37 129.6 43.9 1.3e-37 129.6 43.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEB09515.1 - 2.4e-10 39.9 11.7 2.4e-10 39.9 11.7 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EEB09515.1 - 0.00097 17.7 5.7 0.00097 17.7 5.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyoxalase PF00903.25 EEB09516.1 - 1.8e-39 134.9 0.3 3.4e-21 75.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EEB09516.1 - 3.2e-19 69.2 0.0 3.1e-09 37.1 0.0 3.5 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EEB09516.1 - 4.4e-05 23.7 0.0 0.091 12.9 0.0 3.4 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EEB09516.1 - 7.3e-05 22.7 3.4 0.13 12.2 0.5 4.0 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EEB09516.1 - 0.018 15.8 0.0 1.4 9.8 0.0 2.8 1 1 2 3 3 3 0 Glyoxalase-like domain NIL PF09383.10 EEB09516.1 - 0.1 12.5 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 NIL domain SIS PF01380.22 EEB09517.1 - 6.3e-59 197.5 0.2 4.3e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EEB09517.1 - 6.7e-14 52.2 0.0 2.1e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEB09517.1 - 2.5e-10 40.3 0.0 6.8e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EEB09517.1 - 4.8e-05 22.4 0.0 8.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 EEB09517.1 - 0.043 12.5 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferases class-II SIS_2 PF13580.6 EEB09517.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 1 1 0 1 1 1 0 SIS domain Glu_cys_ligase PF04262.14 EEB09518.1 - 0.06 12.0 0.2 0.068 11.8 0.2 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase CCDC53 PF10152.9 EEB09518.1 - 0.85 10.0 6.6 0.16 12.4 1.7 1.9 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Ammonium_transp PF00909.21 EEB09519.1 - 1.8e-115 385.8 30.4 2.1e-115 385.6 30.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family VEGFR-2_TMD PF17988.1 EEB09519.1 - 0.37 10.3 4.7 0.5 9.8 0.2 2.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain WD40 PF00400.32 EEB09520.1 - 3.1e-26 91.1 10.9 2.2e-06 28.3 0.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09520.1 - 2.2e-05 24.7 0.0 0.54 10.6 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEB09520.1 - 5.7e-05 22.0 8.3 0.11 11.2 0.4 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ku_C PF03730.14 EEB09520.1 - 0.13 13.0 1.5 3.5 8.4 1.8 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Microtub_bind PF13931.6 EEB09520.1 - 0.78 10.1 5.9 0.66 10.4 4.1 1.7 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding RabGAP-TBC PF00566.18 EEB09521.2 - 8.1e-50 169.4 1.2 8.9e-50 169.3 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EEB09522.1 - 6.1e-73 245.4 0.0 1e-72 244.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09522.1 - 1.7e-29 102.9 0.0 2.1e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEB09522.1 - 1.9e-09 37.3 0.0 1.6e-05 24.4 0.0 3.1 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EEB09522.1 - 0.00098 18.0 1.3 0.0036 16.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase MARCKS PF02063.17 EEB09522.1 - 0.012 15.7 18.9 0.018 15.0 18.9 1.2 1 0 0 1 1 1 0 MARCKS family Haspin_kinase PF12330.8 EEB09522.1 - 0.012 14.6 0.2 0.031 13.2 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEB09522.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEB09522.1 - 0.04 13.8 0.0 2.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SRP-alpha_N PF04086.13 EEB09522.1 - 1.5 8.7 17.1 2.3 8.1 17.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SMYLE_N PF18615.1 EEB09522.1 - 1.6 8.2 6.4 2.8 7.4 6.4 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Macoilin PF09726.9 EEB09522.1 - 8.8 4.7 12.5 11 4.4 12.5 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EEB09522.1 - 9.9 4.3 12.5 14 3.8 12.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Met_10 PF02475.16 EEB09523.1 - 4.1e-09 36.5 0.0 9e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EEB09523.1 - 0.034 14.8 0.0 0.43 11.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EEB09524.2 - 1.2e-22 80.5 0.0 2.7e-19 69.4 0.1 3.1 1 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EEB09524.2 - 2.1e-10 40.4 0.0 4.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 EEB09524.2 - 6.2e-07 29.3 0.1 1.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEB09524.2 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EEB09524.2 - 1.4e-06 28.9 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEB09524.2 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EEB09524.2 - 0.00071 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 EEB09524.2 - 0.0036 17.9 0.0 0.0095 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEB09524.2 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EEB09524.2 - 0.021 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 EEB09524.2 - 0.072 12.4 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Mito_carr PF00153.27 EEB09525.1 - 1.3e-39 134.1 7.5 1.8e-17 63.0 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.22 EEB09526.1 - 7.6e-50 169.8 5.1 1.6e-31 109.2 4.4 5.8 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EEB09526.1 - 6.5e-35 120.3 0.0 1.7e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EEB09526.1 - 1.1e-25 90.3 0.2 1.8e-19 69.7 0.0 4.7 4 1 1 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEB09526.1 - 3.2e-13 49.9 0.0 7.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEB09526.1 - 0.00085 18.8 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 EEB09526.1 - 0.0018 17.6 6.8 0.08 12.4 0.2 3.2 3 0 0 3 3 3 2 zinc-ribbon domain DZR PF12773.7 EEB09526.1 - 0.044 13.8 0.5 0.12 12.4 0.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EEB09526.1 - 0.047 13.8 3.0 1.6 8.9 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 EEB09526.1 - 0.048 13.7 6.7 0.095 12.7 0.0 2.9 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1d PF00750.19 EEB09526.1 - 0.051 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) TF_Zn_Ribbon PF08271.12 EEB09526.1 - 0.34 10.5 2.4 4.6 6.8 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ISL3 PF14690.6 EEB09526.1 - 0.35 11.6 3.5 31 5.4 0.0 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 EEB09526.1 - 2.4 8.2 4.5 32 4.6 0.3 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain V-SNARE_C PF12352.8 EEB09527.1 - 1.1e-12 48.0 0.5 1.1e-12 48.0 0.5 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_S46 PF10459.9 EEB09527.1 - 0.075 11.7 2.2 0.094 11.3 2.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Sec20 PF03908.13 EEB09527.1 - 0.11 12.5 2.9 0.18 11.8 0.1 2.3 1 1 2 3 3 3 0 Sec20 Cornichon PF03311.14 EEB09528.1 - 3.4e-39 133.9 10.5 4.1e-39 133.7 10.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2269 PF10027.9 EEB09528.1 - 0.93 9.5 6.4 0.35 10.9 2.7 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF2340 PF10209.9 EEB09529.1 - 6.6e-50 168.6 1.7 7.3e-50 168.4 1.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 EEB09529.1 - 0.00013 22.3 0.1 0.00015 22.1 0.1 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Ank_2 PF12796.7 EEB09530.2 - 0.027 15.1 1.2 0.077 13.6 1.2 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) FAD_binding_8 PF08022.12 EEB09531.1 - 5.1e-23 81.2 0.0 9.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EEB09531.1 - 6.4e-19 68.3 16.7 6.4e-19 68.3 16.7 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEB09531.1 - 7.5e-15 55.4 0.0 1.6e-13 51.1 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain SDF PF00375.18 EEB09531.1 - 0.01 14.9 5.4 0.026 13.5 5.3 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Ni_hydr_CYTB PF01292.20 EEB09531.1 - 8.9 5.9 19.3 0.25 10.9 11.0 2.1 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 eIF2A PF08662.11 EEB09532.1 - 4.8e-39 134.2 1.8 3.1e-37 128.3 0.5 3.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EEB09532.1 - 0.0014 18.4 0.1 0.0031 17.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EEB09532.1 - 0.17 12.8 0.2 28 5.8 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Kinesin PF00225.23 EEB09533.2 - 9.1e-111 370.0 0.1 9.1e-111 370.0 0.1 3.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EEB09533.2 - 5.2e-25 88.1 0.0 3.2e-24 85.6 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding Tape_meas_lam_C PF09718.10 EEB09533.2 - 0.6 10.3 5.4 9.8 6.4 0.1 3.6 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) NEMO PF11577.8 EEB09533.2 - 0.98 9.5 9.9 2.2 8.4 0.2 3.5 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO SATase_N PF06426.14 EEB09533.2 - 5.8 7.4 11.9 0.21 12.0 1.7 3.8 3 2 2 5 5 5 0 Serine acetyltransferase, N-terminal Ribosomal_S28e PF01200.18 EEB09534.1 - 4.7e-33 113.0 1.6 5.2e-33 112.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 EEB09535.1 - 1.8e-50 171.0 0.1 2.3e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EEB09535.1 - 2.2e-27 95.0 0.2 4.3e-27 94.1 0.2 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EEB09535.1 - 0.0005 20.1 0.1 0.0007 19.6 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Red1 PF07964.11 EEB09536.1 - 2.4e-209 697.3 18.3 2.9e-209 697.1 18.3 1.0 1 0 0 1 1 1 1 Rec10 / Red1 DUF956 PF06115.11 EEB09536.1 - 0.12 12.1 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF956) bZIP_2 PF07716.15 EEB09537.1 - 4.6e-12 45.8 13.9 1e-11 44.7 13.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 EEB09537.1 - 0.0017 18.6 0.6 0.0054 17.0 0.6 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 EEB09537.1 - 0.0028 17.7 11.9 0.0056 16.8 11.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EEB09537.1 - 0.0084 16.2 21.0 0.011 15.8 21.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ZapB PF06005.12 EEB09537.1 - 0.03 14.8 1.2 0.03 14.8 1.2 3.0 4 0 0 4 4 4 0 Cell division protein ZapB Putative_G5P PF17426.2 EEB09537.1 - 0.11 12.6 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P PEARLI-4 PF05278.12 EEB09537.1 - 0.18 11.4 3.7 0.45 10.1 3.7 1.6 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Acetyltransf_10 PF13673.7 EEB09538.1 - 1.2e-13 51.1 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB09538.1 - 1.5e-09 38.1 0.1 1.9e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEB09538.1 - 2.2e-07 31.2 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EEB09538.1 - 0.024 15.3 0.2 2.3 9.0 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEB09538.1 - 0.053 13.6 0.0 0.073 13.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lyase_8_N PF08124.11 EEB09538.1 - 0.087 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Ydc2-catalyt PF09159.10 EEB09539.1 - 9.9e-45 153.4 0.1 4.1e-44 151.4 0.1 1.8 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 OrfB_IS605 PF01385.19 EEB09539.1 - 0.00088 19.5 0.2 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 Probable transposase SAP PF02037.27 EEB09539.1 - 0.0037 17.0 0.1 0.0072 16.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 EEB09539.1 - 0.018 15.2 0.0 8.5 6.5 0.0 3.5 1 1 0 3 3 3 0 Poxvirus A22 protein Ribosomal_S9 PF00380.19 EEB09540.1 - 7.3e-40 136.3 0.0 1.1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DKCLD PF08068.12 EEB09541.1 - 1.5e-34 117.8 0.2 2.8e-32 110.6 0.2 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.20 EEB09541.1 - 2.9e-22 78.4 2.1 6.1e-22 77.4 2.1 1.6 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EEB09541.1 - 5.3e-22 77.7 0.9 9.9e-22 76.9 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EEB09541.1 - 8.4e-22 78.1 0.1 5.5e-19 69.0 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 EEB09541.1 - 0.00089 19.5 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 EEB09541.1 - 1.9 8.7 15.1 2.8 8.2 15.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SNF2_N PF00176.23 EEB09542.2 - 1.4e-72 244.3 2.1 3.5e-72 243.1 2.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EEB09542.2 - 8.4e-20 70.6 0.1 3.3e-19 68.7 0.1 2.1 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EEB09542.2 - 1.2e-19 70.3 14.8 1.4e-19 70.2 10.8 3.2 3 0 0 3 3 3 1 HSA Helicase_C PF00271.31 EEB09542.2 - 1.1e-18 67.6 0.3 1.4e-17 64.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09542.2 - 3.6e-11 43.4 0.1 2.2e-10 40.8 0.1 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SnAC PF14619.6 EEB09542.2 - 1.5e-09 38.3 0.4 1.5e-09 38.3 0.4 3.5 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex SWI2_SNF2 PF18766.1 EEB09542.2 - 8.1e-06 25.7 0.0 8.1e-06 25.7 0.0 2.2 3 0 0 3 3 3 1 SWI2/SNF2 ATPase DEAD PF00270.29 EEB09542.2 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 EEB09542.2 - 5.1 7.5 24.4 0.12 12.7 15.4 3.1 3 0 0 3 3 3 0 DNA-binding domain Radical_SAM_C PF16199.5 EEB09543.1 - 3.6e-32 110.2 0.0 8.8e-32 109.0 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EEB09543.1 - 2.5e-20 73.5 0.4 8.2e-20 71.8 0.1 1.9 2 1 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EEB09543.1 - 2.8e-09 37.2 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB09543.1 - 1.6e-06 28.1 0.0 3.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEB09543.1 - 0.0073 16.7 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEB09543.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein E1-E2_ATPase PF00122.20 EEB09544.1 - 9e-34 116.6 2.5 1.2e-32 112.9 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEB09544.1 - 1.1e-14 55.3 0.0 4e-09 37.1 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 EEB09544.1 - 2.8e-07 30.7 0.1 2.8e-07 30.7 0.1 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 EEB09544.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) WD40 PF00400.32 EEB09545.1 - 5.4e-18 65.0 14.3 5.8e-06 26.9 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EEB09545.1 - 2e-15 56.8 0.9 5.1e-15 55.5 0.1 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex FUN14 PF04930.15 EEB09546.1 - 3.3e-13 49.9 0.3 4.6e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 FUN14 family Deltameth_res PF16020.5 EEB09546.1 - 0.037 13.9 0.5 0.071 13.0 0.5 1.4 1 0 0 1 1 1 0 Deltamethrin resistance DUF2982 PF11201.8 EEB09546.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2982) Pkinase PF00069.25 EEB09547.2 - 6.7e-48 163.3 0.0 4.2e-47 160.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09547.2 - 4.2e-28 98.3 0.0 6.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09547.2 - 0.0023 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB09547.2 - 0.033 13.5 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEB09548.2 - 4e-51 173.9 0.0 6.7e-51 173.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09548.2 - 5.4e-31 107.8 0.0 1.6e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09548.2 - 1.9e-05 24.1 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEB09548.2 - 0.029 13.7 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEB09548.2 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_2b PF00587.25 EEB09549.1 - 4.5e-34 118.0 0.0 7.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEB09549.1 - 4.5e-26 91.2 4.9 4.5e-26 91.2 4.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GED PF02212.18 EEB09549.1 - 0.0022 18.1 1.0 0.005 17.0 1.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MAP7 PF05672.11 EEB09549.1 - 0.0036 17.0 0.4 0.0056 16.4 0.4 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family D5_N PF08706.11 EEB09549.1 - 0.052 13.8 0.7 0.11 12.8 0.7 1.5 1 0 0 1 1 1 0 D5 N terminal like Peroxin-3 PF04882.12 EEB09550.1 - 1.3e-07 31.0 8.5 0.00034 19.8 0.8 3.4 1 1 1 2 2 2 2 Peroxin-3 EspB_PE PF18625.1 EEB09550.1 - 0.035 14.6 0.1 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Peptidase_M10 PF00413.24 EEB09550.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Matrixin UreF PF01730.16 EEB09551.1 - 1e-18 68.2 0.1 2.3e-18 67.1 0.0 1.6 1 1 0 1 1 1 1 UreF DUF3969 PF13108.6 EEB09551.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) DUF4647 PF15504.6 EEB09552.1 - 0.011 14.8 1.0 0.016 14.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RhoGAP PF00620.27 EEB09553.2 - 4.5e-39 133.7 0.0 9.9e-39 132.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEB09553.2 - 7.5e-12 45.3 35.0 6.7e-08 32.6 6.5 3.8 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.22 EEB09553.2 - 2.8e-06 27.1 6.0 2.8e-06 27.1 6.0 3.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RR_TM4-6 PF06459.12 EEB09553.2 - 5.5 6.7 10.1 25 4.6 10.1 2.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SIP1 PF04938.12 EEB09554.1 - 0.036 13.8 4.2 0.027 14.2 1.5 2.1 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-C2HC_2 PF13913.6 EEB09554.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Nop25 PF09805.9 EEB09555.1 - 1.3e-28 100.2 22.4 2.4e-28 99.3 22.4 1.4 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) WDCP PF15390.6 EEB09555.1 - 2 6.7 5.5 1.9 6.7 5.5 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family zf-C3H1 PF10650.9 EEB09556.1 - 1e-10 41.1 0.6 1.9e-10 40.3 0.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain PAS_3 PF08447.12 EEB09556.1 - 0.042 14.1 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Alveol-reg_P311 PF11092.8 EEB09557.1 - 0.1 12.7 0.3 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Gly_transf_sug PF04488.15 EEB09558.1 - 2.7e-12 47.2 0.0 6.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EEB09558.1 - 0.068 12.5 0.1 10 5.3 0.0 2.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain CNH PF00780.22 EEB09559.1 - 1.3e-69 234.8 0.1 3.2e-69 233.6 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EEB09559.1 - 4.3e-37 127.2 0.0 1e-36 126.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EEB09559.1 - 4.1e-34 118.4 0.9 7e-34 117.7 0.9 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EEB09559.1 - 4.6e-14 52.2 0.0 9.8e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DEAD PF00270.29 EEB09560.1 - 9.7e-46 155.7 0.7 1.7e-45 154.9 0.7 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09560.1 - 1.5e-30 105.8 0.3 9.7e-30 103.2 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09560.1 - 8.7e-06 25.8 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEB09560.1 - 0.00016 21.4 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB09560.1 - 0.0011 19.4 1.7 0.0065 16.8 0.4 2.3 2 1 0 2 2 2 1 AAA domain fragilysinNterm PF16376.5 EEB09560.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of fragilysin CMS1 PF14617.6 EEB09560.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 EEB09560.1 - 0.056 13.0 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EEB09560.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EEB09560.1 - 0.12 12.4 0.4 0.47 10.4 0.4 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.14 EEB09560.1 - 0.12 12.3 0.1 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein SUIM_assoc PF16619.5 EEB09562.1 - 1.4 9.1 6.9 2.7 8.1 1.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 EEB09563.2 - 6.7e-59 199.4 0.0 1.2e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09563.2 - 9.4e-30 103.8 0.0 1.9e-28 99.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEB09563.2 - 2.8e-05 23.6 0.1 0.0058 16.0 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 EEB09563.2 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EEB09563.2 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exotox-A_bind PF09101.10 EEB09563.2 - 0.047 13.0 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Exotoxin A binding Kdo PF06293.14 EEB09563.2 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_binding_1 PF01035.20 EEB09564.2 - 2.5e-26 91.6 0.0 3.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIIC_sub6 PF10419.9 EEB09565.1 - 3.2e-11 43.0 0.0 5.4e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain UQ_con PF00179.26 EEB09566.1 - 6.3e-43 145.8 0.0 7.1e-43 145.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEB09566.1 - 0.0002 21.0 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEB09566.1 - 0.048 13.5 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF1187 PF06688.11 EEB09567.2 - 0.028 14.8 0.1 0.049 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) EF-hand_1 PF00036.32 EEB09568.1 - 1.6e-15 55.4 0.1 0.00091 18.6 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EEB09568.1 - 1.7e-13 50.8 0.1 2.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEB09568.1 - 2.3e-13 48.9 0.1 4.9e-05 22.9 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 EEB09568.1 - 4.2e-10 39.8 0.0 7.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EEB09568.1 - 8.2e-08 32.0 1.7 0.016 15.1 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EEB09568.1 - 0.02 14.9 0.2 5.1 7.1 0.0 2.5 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EEB09568.1 - 0.022 14.3 1.8 0.82 9.3 0.2 2.6 2 0 0 2 2 2 0 EF hand SurA_N_2 PF13623.6 EEB09568.1 - 0.03 14.2 0.2 2.2 8.1 0.0 2.3 1 1 0 2 2 2 0 SurA N-terminal domain FGAR-AT_linker PF18072.1 EEB09568.1 - 0.054 14.0 0.3 0.43 11.2 0.0 2.4 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Caleosin PF05042.13 EEB09568.1 - 0.064 13.2 0.1 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein DUF2040 PF09745.9 EEB09569.1 - 2.6e-23 82.4 15.7 2.6e-23 82.4 15.7 3.8 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Med22 PF06179.12 EEB09570.1 - 4e-16 59.1 0.9 6.6e-16 58.4 0.9 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Prp19 PF08606.11 EEB09571.1 - 4e-27 94.0 2.0 8.3e-27 93.0 2.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EEB09571.1 - 1.4e-13 51.0 0.0 3.1e-06 27.4 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEB09571.1 - 9.1e-11 42.2 1.1 0.086 13.7 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat U-box PF04564.15 EEB09571.1 - 0.00014 21.9 0.0 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EEB09571.1 - 0.032 14.0 0.0 0.13 12.1 0.0 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.32 EEB09572.1 - 2.5e-10 40.8 4.9 0.096 13.6 0.3 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.6 EEB09572.1 - 0.024 15.1 1.5 2.8 8.5 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Peptidase_S8 PF00082.22 EEB09573.1 - 9.3e-37 126.9 8.0 1.6e-36 126.1 8.0 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEB09573.1 - 7.4e-15 55.4 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pox_D3 PF04580.13 EEB09574.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein PQ-loop PF04193.14 EEB09575.1 - 4e-31 106.6 8.3 1.1e-20 73.1 1.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Per1 PF04080.13 EEB09575.1 - 0.12 12.2 4.1 0.17 11.6 4.1 1.2 1 0 0 1 1 1 0 Per1-like family ER_lumen_recept PF00810.18 EEB09575.1 - 1.1 10.1 8.8 0.78 10.6 0.2 2.6 2 1 0 2 2 2 0 ER lumen protein retaining receptor BTP PF05232.12 EEB09575.1 - 6.7 6.9 11.5 0.94 9.6 0.7 3.4 3 0 0 3 3 3 0 Chlorhexidine efflux transporter Sod_Fe_C PF02777.18 EEB09576.1 - 1.8e-19 69.8 0.2 1.1e-18 67.2 0.2 2.1 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EEB09576.1 - 2.2e-05 24.8 0.2 5.4e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Alpha-amylase PF00128.24 EEB09577.1 - 1.1e-57 196.2 0.0 1.9e-57 195.4 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EEB09577.1 - 2e-05 24.8 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Abhydrolase_1 PF00561.20 EEB09578.2 - 5.5e-23 81.9 0.1 3e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EEB09578.2 - 1.1e-18 66.5 0.1 1.9e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EEB09578.2 - 6.6e-05 22.3 0.0 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EEB09578.2 - 0.0039 16.9 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) IMS PF00817.20 EEB09579.1 - 4.4e-40 137.1 0.0 1.6e-39 135.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family Acetyltransf_13 PF13880.6 EEB09579.1 - 4.6e-27 93.8 0.0 1.2e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EEB09579.1 - 4.1e-11 42.5 1.7 4.1e-11 42.5 1.7 2.2 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf_UBZ PF18439.1 EEB09579.1 - 7.6e-11 41.4 1.0 7.6e-11 41.4 1.0 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Acetyltransf_7 PF13508.7 EEB09579.1 - 0.00049 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEB09579.1 - 0.00069 19.8 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEB09579.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1963 PF09234.10 EEB09579.1 - 0.081 13.4 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) MBOAT PF03062.19 EEB09580.1 - 7e-62 209.8 7.0 7e-62 209.8 7.0 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 EEB09580.1 - 0.14 12.5 0.2 0.29 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Eaf7 PF07904.13 EEB09581.1 - 1.7e-19 70.2 0.1 4e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 AA_permease PF00324.21 EEB09582.2 - 2.4e-90 303.5 42.6 4.3e-90 302.6 32.5 2.3 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EEB09582.2 - 5.1e-35 121.1 39.1 7.1e-35 120.6 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2061 PF09834.9 EEB09582.2 - 0.0024 18.3 0.8 0.024 15.1 0.8 2.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) Utp13 PF08625.11 EEB09589.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Utp13 PF08625.11 EEB09590.2 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain ERG4_ERG24 PF01222.17 EEB09593.1 - 1.2e-145 485.5 18.3 1.6e-145 485.2 18.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEB09593.1 - 8e-06 25.5 0.6 8e-06 25.5 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) DUF4271 PF14093.6 EEB09593.1 - 0.06 13.2 9.4 0.16 11.9 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Fungal_trans PF04082.18 EEB09594.1 - 2e-24 86.1 1.7 3.1e-24 85.5 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEB09594.1 - 4.8e-12 45.8 8.9 8.4e-12 45.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Forkhead PF00250.18 EEB09595.1 - 2.2e-36 124.0 0.8 4.1e-36 123.1 0.8 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EEB09595.1 - 2.1e-06 28.0 0.0 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ribosomal_S3_C PF00189.20 EEB09596.1 - 4.1e-23 81.7 0.1 1.9e-22 79.5 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EEB09596.1 - 2e-14 53.1 0.1 3.9e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EEB09596.1 - 0.17 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ING PF12998.7 EEB09597.2 - 0.0083 16.7 0.1 0.016 15.7 0.1 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Topoisom_bac PF01131.20 EEB09598.1 - 1.4e-100 337.3 0.0 1.6e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EEB09598.1 - 9.8e-20 70.7 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain BAG PF02179.16 EEB09599.1 - 3.1e-21 75.6 0.8 5.7e-21 74.7 0.8 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EEB09599.1 - 3.7e-08 33.0 0.4 8.1e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_5 PF18037.1 EEB09599.1 - 1.9e-06 28.1 0.2 4.3e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EEB09599.1 - 0.00058 19.6 0.1 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EEB09599.1 - 0.0053 16.8 0.7 0.016 15.3 0.0 2.1 2 1 1 3 3 3 1 Ubiquitin-like domain UN_NPL4 PF11543.8 EEB09599.1 - 0.032 14.7 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RNase_PH PF01138.21 EEB09600.1 - 6.8e-15 55.7 0.0 1.1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEB09600.1 - 0.0014 18.6 0.1 0.0041 17.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Peptidase_S10 PF00450.22 EEB09601.1 - 9.1e-102 341.6 0.1 1.1e-101 341.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 EEB09601.1 - 0.016 14.7 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Med18 PF09637.10 EEB09602.2 - 1.1e-28 100.7 0.0 5.3e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 Med18 protein Alg14 PF08660.11 EEB09603.1 - 7.1e-62 208.4 0.0 8.4e-62 208.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PXA PF02194.15 EEB09604.1 - 5e-25 88.5 1.4 1.2e-24 87.2 0.2 2.1 2 0 0 2 2 2 1 PXA domain Catalase PF00199.19 EEB09605.1 - 1.1e-191 637.0 0.2 1.4e-191 636.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEB09605.1 - 8e-14 51.6 0.1 2.3e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive RNase_PH PF01138.21 EEB09606.1 - 1.4e-20 74.2 0.0 3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEB09606.1 - 2.3e-12 46.8 0.0 4.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.29 EEB09607.2 - 2.7e-41 139.2 4.3 2.4e-16 59.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEB09607.2 - 4.1e-10 39.3 1.7 0.045 13.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEB09607.2 - 1.1e-06 28.5 0.4 0.35 10.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EEB09607.2 - 1.9e-05 24.7 1.4 0.052 13.6 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Dsh_C PF12316.8 EEB09607.2 - 0.0057 17.1 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal D-ser_dehydrat PF14031.6 EEB09608.1 - 6.9e-27 93.9 0.2 4e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EEB09608.1 - 2.9e-19 69.6 0.1 3.8e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MFS_1 PF07690.16 EEB09609.1 - 1e-24 87.2 25.8 1e-24 87.2 25.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily GWT1 PF06423.12 EEB09609.1 - 0.027 14.6 3.1 0.038 14.1 1.2 2.3 1 1 1 2 2 2 0 GWT1 UPF0542 PF15086.6 EEB09609.1 - 0.74 9.8 4.3 0.75 9.8 0.3 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 MFS_1 PF07690.16 EEB09610.1 - 5.6e-28 97.9 28.2 8.9e-28 97.2 28.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sas10_Utp3 PF04000.15 EEB09610.1 - 0.13 12.9 0.1 0.38 11.4 0.1 1.8 2 0 0 2 2 2 0 Sas10/Utp3/C1D family NicO PF03824.16 EEB09611.1 - 4.5e-57 193.6 13.1 6.5e-57 193.0 13.1 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF4646 PF15496.6 EEB09612.1 - 1.1e-24 87.4 0.0 1.8e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Utp13 PF08625.11 EEB09615.1 - 0.15 12.0 0.1 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Sybindin PF04099.12 EEB09617.1 - 2.9e-21 75.9 0.8 4.3e-21 75.3 0.8 1.3 1 1 0 1 1 1 1 Sybindin-like family Fcf2 PF08698.11 EEB09618.1 - 5.7e-35 119.6 0.2 4.4e-34 116.7 0.0 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing RFX_DNA_binding PF02257.15 EEB09619.2 - 3e-33 114.3 0.2 2e-32 111.7 0.1 2.2 2 0 0 2 2 2 1 RFX DNA-binding domain DUF1067 PF06362.11 EEB09619.2 - 0.058 14.2 1.2 0.22 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1067) tRNA-synt_1b PF00579.25 EEB09620.2 - 2.2e-68 230.7 0.0 3.6e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CLASP_N PF12348.8 EEB09621.1 - 7e-82 274.4 10.9 1.6e-71 240.5 0.7 2.7 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.6 EEB09621.1 - 0.0034 17.7 0.1 5.6 7.4 0.0 4.8 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EEB09621.1 - 0.0088 16.2 0.2 77 4.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat TAF6_C PF07571.13 EEB09621.1 - 0.036 14.4 0.4 2.1 8.8 0.0 3.9 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain UME PF08064.13 EEB09621.1 - 0.047 13.6 1.0 31 4.5 0.0 4.0 3 1 1 4 4 4 0 UME (NUC010) domain DUF4476 PF14771.6 EEB09621.1 - 0.063 13.6 0.3 11 6.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) TPP_enzyme_N PF02776.18 EEB09622.1 - 5e-30 104.4 0.0 8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEB09622.1 - 2.5e-20 72.6 0.0 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEB09622.1 - 7.7e-18 64.7 0.0 3.1e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EEB09622.1 - 0.00047 19.5 0.0 0.00073 18.8 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Lyase_1 PF00206.20 EEB09623.2 - 7.7e-118 393.4 0.0 9.9e-118 393.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EEB09623.2 - 1.7e-21 76.4 0.0 3.5e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Proteasom_PSMB PF10508.9 EEB09624.1 - 5e-08 31.9 0.1 1.7e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit RasGEF_N_2 PF14663.6 EEB09624.1 - 0.00089 19.6 0.6 0.19 12.1 0.1 3.0 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Flavokinase PF01687.17 EEB09625.1 - 1.4e-34 118.7 0.0 1.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Smr PF01713.21 EEB09625.1 - 0.063 13.6 0.0 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 Smr domain RHH_3 PF12651.7 EEB09625.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain ANAPC4_WD40 PF12894.7 EEB09626.2 - 1e-06 28.9 0.0 0.0014 18.9 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EEB09626.2 - 0.056 12.8 0.0 0.092 12.0 0.0 1.4 1 1 0 1 1 1 0 CPSF A subunit region WD40 PF00400.32 EEB09626.2 - 0.093 13.6 4.2 12 6.9 0.1 4.0 3 1 1 4 4 4 0 WD domain, G-beta repeat Ribosomal_L10 PF00466.20 EEB09627.1 - 2.3e-24 85.4 2.0 4.9e-24 84.4 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EEB09627.1 - 3e-22 78.4 0.0 5e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EEB09627.1 - 1.2e-17 64.3 6.6 1.2e-17 64.3 6.6 2.2 3 0 0 3 3 3 1 60s Acidic ribosomal protein WD40 PF00400.32 EEB09628.1 - 2.4e-08 34.5 2.3 0.035 15.0 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09628.1 - 6.2e-05 23.2 0.0 0.064 13.6 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Guanylate_kin PF00625.21 EEB09629.1 - 1.4e-64 217.1 0.0 1.7e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.27 EEB09629.1 - 6.3e-06 26.7 0.0 8.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EEB09629.1 - 8.9e-06 26.2 0.0 1.7e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EEB09629.1 - 1e-05 26.1 0.1 3.4e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEB09629.1 - 1.2e-05 25.6 0.1 4e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EEB09629.1 - 2.6e-05 24.4 0.1 0.00049 20.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEB09629.1 - 5.2e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EEB09629.1 - 6.5e-05 22.9 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 EEB09629.1 - 7.6e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EEB09629.1 - 0.00014 22.0 0.0 0.00033 20.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EEB09629.1 - 0.00035 21.0 0.0 0.00068 20.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEB09629.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EEB09629.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Roc PF08477.13 EEB09629.1 - 0.002 18.3 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EEB09629.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EEB09629.1 - 0.0035 17.4 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EEB09629.1 - 0.0045 17.0 0.0 0.0076 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EEB09629.1 - 0.0045 16.9 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_17 PF13207.6 EEB09629.1 - 0.0061 17.0 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain PTS_IIB PF02302.17 EEB09629.1 - 0.0076 16.9 0.0 5.4 7.8 0.0 3.1 2 1 1 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit AAA_28 PF13521.6 EEB09629.1 - 0.0077 16.5 0.0 0.065 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEB09629.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EEB09629.1 - 0.014 15.2 0.1 0.019 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEB09629.1 - 0.014 15.1 0.1 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 EEB09629.1 - 0.068 13.1 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 EEB09629.1 - 0.082 12.6 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEB09629.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EEB09629.1 - 0.095 12.7 0.0 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ras PF00071.22 EEB09629.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras family Septin PF00735.18 EEB09629.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.19 EEB09629.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EEB09629.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glyco_hydro_76 PF03663.14 EEB09630.2 - 2e-123 412.6 22.2 2.4e-123 412.3 22.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 EEB09631.1 - 1.2e-134 449.4 24.0 1.4e-134 449.2 24.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEB09631.1 - 0.025 13.6 6.9 0.17 11.0 0.8 2.5 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 TFIIF_beta PF02270.15 EEB09632.1 - 1.1e-29 102.3 0.2 2e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EEB09632.1 - 1.4e-22 80.8 4.0 2.8e-18 66.9 0.2 2.9 2 1 1 3 3 3 2 TFIIF, beta subunit N-terminus WD40 PF00400.32 EEB09633.2 - 2.6e-20 72.3 12.9 0.0005 20.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09633.2 - 9.3e-11 41.9 5.7 0.0046 17.2 0.6 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEB09633.2 - 4.7e-06 26.6 0.2 0.012 15.5 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EEB09633.2 - 0.00054 19.4 0.0 0.012 14.9 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Mcl1_mid PF12341.8 EEB09633.2 - 0.0068 15.8 0.0 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region Sec23_trunk PF04811.15 EEB09634.1 - 4.8e-16 59.1 0.2 7.7e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEB09634.1 - 1.3e-10 41.0 0.0 3.6e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EEB09634.1 - 4.3e-09 36.3 4.9 2.5e-08 33.8 4.9 2.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EEB09634.1 - 3.1e-05 24.6 0.2 0.00012 22.8 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain ATP-synt_D PF01813.17 EEB09634.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.6 2 0 0 2 2 2 0 ATP synthase subunit D Sec23_trunk PF04811.15 EEB09635.1 - 1.1e-39 136.4 0.3 1.8e-39 135.8 0.3 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEB09635.1 - 6.5e-14 51.6 1.0 4.2e-13 49.0 0.4 2.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEB09635.1 - 2.5e-09 37.7 0.1 4.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEB09635.1 - 7.6e-05 22.7 1.4 0.00015 21.7 1.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 EEB09635.1 - 0.0085 16.7 0.2 1.9 9.2 0.4 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain TF_Zn_Ribbon PF08271.12 EEB09635.1 - 0.068 12.7 0.4 0.15 11.6 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Myb_DNA-binding PF00249.31 EEB09636.1 - 1.6e-24 85.8 8.1 2.6e-12 46.7 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEB09636.1 - 1.7e-17 63.4 10.5 1.1e-11 44.7 0.9 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EEB09636.1 - 0.28 11.6 13.0 0.12 12.7 0.6 4.0 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain tRNA-synt_2 PF00152.20 EEB09637.1 - 4.1e-80 269.2 0.0 5.8e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEB09637.1 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RE_SinI PF09570.10 EEB09637.1 - 0.078 12.2 0.3 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 SinI restriction endonuclease UQ_con PF00179.26 EEB09638.1 - 1e-40 138.6 0.0 1.2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EEB09638.1 - 0.12 12.0 0.2 0.2 11.3 0.2 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_M20 PF01546.28 EEB09639.1 - 1.5e-31 109.7 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEB09639.1 - 9.2e-15 54.5 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Trehalase PF01204.18 EEB09640.1 - 8.8e-191 635.2 0.9 1.1e-190 634.9 0.9 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EEB09640.1 - 2.4e-16 59.2 0.2 4.1e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Nmad5 PF18757.1 EEB09641.1 - 0.014 15.6 0.7 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 DUF3847 PF12958.7 EEB09641.1 - 0.043 13.9 1.3 0.1 12.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) MIT PF04212.18 EEB09641.1 - 0.11 12.6 1.3 0.22 11.6 1.3 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Val_tRNA-synt_C PF10458.9 EEB09641.1 - 0.12 12.7 0.2 11 6.4 0.3 2.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm EMP24_GP25L PF01105.24 EEB09641.1 - 0.37 10.7 2.3 0.25 11.2 0.4 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlxA PF14282.6 EEB09641.1 - 1.8 8.6 9.2 0.13 12.3 3.7 2.0 2 0 0 2 2 2 0 FlxA-like protein GTP_EFTU PF00009.27 EEB09643.2 - 1.6e-58 197.5 0.0 2.3e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EEB09643.2 - 1.3e-22 79.7 0.0 2.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEB09643.2 - 5.2e-14 52.0 0.0 1.1e-06 28.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEB09643.2 - 8.9e-05 22.8 0.3 0.00029 21.2 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEB09643.2 - 0.00093 19.3 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EEB09643.2 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RRM_1 PF00076.22 EEB09644.1 - 2.3e-27 94.6 0.3 3.6e-12 45.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB09644.1 - 0.069 13.2 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SAPS PF04499.15 EEB09644.1 - 6.3 5.5 17.6 2.4 6.8 7.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RRM_3 PF08777.11 EEB09644.1 - 7.8 6.6 11.0 7.1 6.7 0.3 4.2 3 1 1 4 4 4 0 RNA binding motif Glyco_hydro_cc PF11790.8 EEB09645.1 - 3.9e-60 203.4 2.9 5.4e-60 202.9 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.17 EEB09645.1 - 0.00052 18.7 0.0 0.00079 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 GHMP_kinases_N PF00288.26 EEB09646.1 - 4.4e-12 46.0 7.3 4.4e-12 46.0 7.3 2.8 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEB09646.1 - 3.2e-10 40.2 0.1 8e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EEB09646.1 - 0.027 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PAH PF02671.21 EEB09646.1 - 0.19 11.9 0.0 2.1 8.5 0.0 2.5 3 0 0 3 3 3 0 Paired amphipathic helix repeat NMT1 PF09084.11 EEB09647.1 - 1.4e-74 250.7 0.0 1.7e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EEB09647.1 - 0.00068 19.4 0.0 0.33 10.6 0.0 3.1 3 1 1 4 4 4 2 NMT1-like family Phosphonate-bd PF12974.7 EEB09647.1 - 0.0049 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 EEB09647.1 - 0.05 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 EEB09647.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 VIT1 PF01988.19 EEB09648.1 - 2e-56 191.3 6.6 2.2e-56 191.1 6.6 1.0 1 0 0 1 1 1 1 VIT family RNA12 PF10443.9 EEB09648.1 - 0.00064 18.6 0.1 0.0025 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA12 protein Chitin_synth_1 PF01644.17 EEB09649.1 - 3.1e-78 261.4 0.0 5.2e-78 260.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEB09649.1 - 6.3e-29 99.7 0.3 2.1e-28 98.1 0.2 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEB09649.1 - 2.1e-27 96.0 0.1 4.8e-21 75.0 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEB09649.1 - 4.3e-08 33.3 11.4 4.3e-08 33.3 11.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEB09649.1 - 0.00016 21.6 0.0 0.00091 19.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SAWADEE PF16719.5 EEB09649.1 - 0.0031 17.5 0.0 0.097 12.7 0.0 2.3 2 0 0 2 2 2 1 SAWADEE domain DUF5310 PF17237.2 EEB09649.1 - 0.057 13.3 0.7 0.29 11.0 0.7 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5310) NUDIX PF00293.28 EEB09650.1 - 3.5e-15 56.2 0.2 1.8e-14 53.9 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain DUF3445 PF11927.8 EEB09650.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Calcipressin PF04847.12 EEB09651.1 - 3.1e-17 62.9 0.0 4.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Calcipressin UPF0029 PF01205.19 EEB09652.1 - 3.6e-32 110.8 0.2 6.6e-32 110.0 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EEB09652.1 - 4.3e-06 27.0 4.8 1.1e-05 25.7 1.1 3.0 2 1 0 2 2 2 1 RWD domain EHN PF06441.12 EEB09652.1 - 0.085 13.2 3.6 0.2 12.0 3.5 1.6 1 1 0 1 1 1 0 Epoxide hydrolase N terminus YchF-GTPase_C PF06071.13 EEB09653.1 - 1.9e-35 120.9 0.2 4.5e-35 119.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EEB09653.1 - 2.3e-18 66.3 0.0 1.5e-17 63.8 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB09653.1 - 1.1e-05 25.1 0.0 3.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EEB09653.1 - 0.047 12.7 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EEB09653.1 - 0.057 14.0 0.1 1.7 9.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 EEB09653.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SSP160 PF06933.11 EEB09654.1 - 0.39 8.9 16.2 0.43 8.7 16.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Enamelin PF15362.6 EEB09654.1 - 9.3 4.4 7.5 10 4.3 7.5 1.0 1 0 0 1 1 1 0 Enamelin DNA_pol_E_B PF04042.16 EEB09655.2 - 2.2e-39 135.0 0.2 3.2e-39 134.5 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EEB09655.2 - 3.5e-33 114.5 0.0 6.6e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CBFD_NFYB_HMF PF00808.23 EEB09657.2 - 1.8e-12 47.3 0.0 5.1e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEB09657.2 - 0.0026 18.1 0.2 0.0057 17.0 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.11 EEB09657.2 - 0.044 13.9 2.4 0.082 13.0 0.1 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF1931) NGP1NT PF08153.12 EEB09657.2 - 0.064 13.4 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 NGP1NT (NUC091) domain LSM PF01423.22 EEB09658.2 - 1.1e-15 57.1 0.7 1.7e-15 56.5 0.7 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEB09658.2 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Hfq protein PIGA PF08288.12 EEB09659.1 - 3.9e-45 152.4 1.5 1.6e-44 150.4 0.5 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EEB09659.1 - 1.6e-28 99.4 0.0 2.1e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEB09659.1 - 3.7e-27 95.4 0.0 5.2e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EEB09659.1 - 1.9e-23 83.3 0.0 4.3e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEB09659.1 - 6.1e-13 49.5 0.0 9.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EEB09659.1 - 0.0013 18.8 0.2 0.0034 17.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EEB09659.1 - 0.0021 18.4 0.0 0.0057 17.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pribosyl_synth PF14572.6 EEB09660.1 - 2.3e-36 125.5 2.7 3.5e-32 111.9 1.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EEB09660.1 - 3.1e-35 120.6 0.0 7.7e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EEB09660.1 - 1.8e-13 50.3 0.1 3.7e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEB09660.1 - 0.00045 19.7 0.1 0.00076 19.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EEB09660.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase CTP_transf_1 PF01148.20 EEB09661.1 - 2e-06 27.8 0.9 2.5e-06 27.4 0.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family MAD PF05557.13 EEB09662.1 - 4.4e-82 276.5 83.1 5.9e-82 276.1 83.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Golgin_A5 PF09787.9 EEB09662.1 - 0.0079 15.7 11.4 0.0079 15.7 11.4 4.3 2 2 2 4 4 4 1 Golgin subfamily A member 5 bZIP_1 PF00170.21 EEB09662.1 - 0.013 15.6 2.8 0.013 15.6 2.8 11.3 7 4 6 13 13 13 0 bZIP transcription factor Lactamase_B_4 PF13691.6 EEB09663.1 - 8e-21 73.5 0.0 4.9e-19 67.8 0.0 2.6 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EEB09663.1 - 1.6e-14 53.9 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEB09663.1 - 2.2e-05 24.6 0.0 0.00024 21.2 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_4 PF12763.7 EEB09664.1 - 1.3e-27 95.8 0.0 4.1e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 EEB09664.1 - 9.9e-19 67.5 359.8 7.5e-05 23.1 56.0 14.6 5 3 4 9 9 7 4 Domain of unknown function (DUF1720) WH2 PF02205.20 EEB09664.1 - 3e-08 33.2 0.1 5.8e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.6 EEB09664.1 - 7.8e-05 23.0 0.2 0.0055 17.1 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EEB09664.1 - 8.5e-05 21.8 0.0 3.2 7.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EEB09664.1 - 0.022 14.7 2.3 6.6 7.0 0.0 3.1 4 0 0 4 4 3 0 EF-hand domain DUF2959 PF11172.8 EEB09664.1 - 0.033 14.3 1.8 0.12 12.5 1.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) HalX PF08663.10 EEB09664.1 - 0.062 13.6 3.2 0.15 12.4 1.2 2.6 2 0 0 2 2 2 0 HalX domain GAS PF13851.6 EEB09664.1 - 0.2 11.0 9.4 0.2 11.0 6.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 EEB09664.1 - 0.44 10.9 5.2 1.5 9.2 1.8 2.9 2 0 0 2 2 2 0 Syntaxin-like protein V_ATPase_I PF01496.19 EEB09664.1 - 1.1 7.1 2.1 1.2 7.0 0.8 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 EEB09665.2 - 2.8e-44 150.8 40.2 3.7e-44 150.3 40.2 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EEB09665.2 - 7.8e-09 35.3 41.7 0.00052 19.5 8.9 3.0 1 1 2 3 3 3 3 Tropomyosin KLRAQ PF10205.9 EEB09665.2 - 1.7e-05 25.0 27.8 5.4e-05 23.4 12.1 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Laminin_II PF06009.12 EEB09665.2 - 2e-05 24.6 25.6 0.016 15.2 9.4 2.7 1 1 1 2 2 2 2 Laminin Domain II DUF4200 PF13863.6 EEB09665.2 - 2.4e-05 24.7 37.7 0.0022 18.4 12.6 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 EEB09665.2 - 3.9e-05 23.9 26.6 0.0036 17.7 4.1 4.0 2 2 2 4 4 4 2 Flagella accessory protein C (FlaC) APG6_N PF17675.1 EEB09665.2 - 4.9e-05 23.9 48.1 0.006 17.1 19.7 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region GAS PF13851.6 EEB09665.2 - 9.6e-05 21.8 35.5 0.0048 16.3 24.8 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.12 EEB09665.2 - 0.00013 21.7 30.6 0.00079 19.1 30.6 2.1 1 1 0 1 1 1 1 PspA/IM30 family Filament PF00038.21 EEB09665.2 - 0.00017 21.3 32.0 0.011 15.3 17.4 2.0 1 1 1 2 2 2 2 Intermediate filament protein ATG16 PF08614.11 EEB09665.2 - 0.00021 21.6 39.2 0.073 13.3 16.5 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 EEB09665.2 - 0.00046 20.3 39.0 0.0031 17.6 17.2 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus FliJ PF02050.16 EEB09665.2 - 0.00058 20.1 27.2 0.00072 19.8 11.6 3.1 1 1 2 3 3 3 1 Flagellar FliJ protein Atg14 PF10186.9 EEB09665.2 - 0.00062 18.9 26.5 0.0012 18.0 26.4 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EEB09665.2 - 0.00076 18.5 39.5 0.01 14.7 15.6 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EEB09665.2 - 0.00096 19.4 4.4 0.00096 19.4 4.4 3.7 1 1 3 4 4 4 2 ABC transporter C-terminal domain DUF3450 PF11932.8 EEB09665.2 - 0.0014 18.0 32.2 0.023 14.0 8.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 EEB09665.2 - 0.0014 18.8 27.0 0.3 11.4 3.8 3.4 1 1 3 4 4 4 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EEB09665.2 - 0.0034 17.8 16.7 0.3 11.6 7.7 2.8 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 EEB09665.2 - 0.0039 17.8 19.2 0.0039 17.8 19.2 3.1 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF745 PF05335.13 EEB09665.2 - 0.0063 16.3 24.7 0.082 12.6 4.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.9 EEB09665.2 - 0.0089 16.1 17.1 0.0089 16.1 17.1 3.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 EEB09665.2 - 0.0089 15.8 17.9 0.0089 15.8 17.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) FH2 PF02181.23 EEB09665.2 - 0.011 14.9 8.0 0.011 14.9 8.0 2.9 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF4164 PF13747.6 EEB09665.2 - 0.012 15.9 14.0 0.012 15.9 14.0 2.7 1 1 1 2 2 1 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 EEB09665.2 - 0.012 15.6 41.5 2.5 8.2 18.5 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EEB09665.2 - 0.014 15.6 18.0 0.014 15.6 18.0 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 EEB09665.2 - 0.014 15.9 33.5 0.015 15.7 28.2 2.0 1 1 1 2 2 2 0 Fez1 HMMR_N PF15905.5 EEB09665.2 - 0.017 14.6 35.3 0.022 14.2 35.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phage_GP20 PF06810.11 EEB09665.2 - 0.018 14.8 16.0 0.018 14.8 16.0 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 FPP PF05911.11 EEB09665.2 - 0.021 13.1 36.2 0.22 9.6 2.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF724 PF05266.14 EEB09665.2 - 0.022 14.6 32.1 0.027 14.3 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 EEB09665.2 - 0.023 12.2 33.8 0.026 12.1 33.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 EEB09665.2 - 0.026 14.9 41.7 0.48 10.8 14.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 EEB09665.2 - 0.027 14.6 34.1 0.48 10.5 15.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 EEB09665.2 - 0.032 14.3 34.5 0.015 15.4 24.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 EEB09665.2 - 0.032 14.3 18.8 0.27 11.3 5.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TACC_C PF05010.14 EEB09665.2 - 0.037 13.8 27.1 0.05 13.4 27.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DHR10 PF18595.1 EEB09665.2 - 0.04 14.0 42.8 0.067 13.2 21.1 2.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 EEB09665.2 - 0.041 13.8 31.7 0.47 10.4 2.8 4.1 1 1 4 5 5 5 0 Prefoldin subunit APG17 PF04108.12 EEB09665.2 - 0.067 12.3 21.1 0.5 9.4 21.0 2.0 1 1 0 1 1 1 0 Autophagy protein Apg17 EzrA PF06160.12 EEB09665.2 - 0.069 11.3 32.5 0.11 10.7 12.9 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA KxDL PF10241.9 EEB09665.2 - 0.073 13.4 21.3 2.8 8.3 3.7 4.0 1 1 2 3 3 3 0 Uncharacterized conserved protein Vps53_N PF04100.12 EEB09665.2 - 0.075 12.0 17.3 0.12 11.3 16.6 1.8 1 1 0 1 1 1 0 Vps53-like, N-terminal Snapin_Pallidin PF14712.6 EEB09665.2 - 0.079 13.4 27.9 0.53 10.7 17.5 3.3 1 1 2 3 3 3 0 Snapin/Pallidin WXG100 PF06013.12 EEB09665.2 - 0.083 13.1 14.0 0.11 12.7 4.7 3.6 1 1 2 3 3 3 0 Proteins of 100 residues with WXG KELK PF15796.5 EEB09665.2 - 0.091 13.2 39.0 0.12 12.8 3.3 4.0 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec8_exocyst PF04048.14 EEB09665.2 - 0.092 12.6 20.6 0.34 10.8 4.3 3.0 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.6 EEB09665.2 - 0.12 11.1 29.7 0.2 10.2 29.7 1.4 1 1 0 1 1 1 0 AAA domain MAD PF05557.13 EEB09665.2 - 0.12 10.7 34.5 0.077 11.4 17.0 1.9 1 1 1 2 2 2 0 Mitotic checkpoint protein BRE1 PF08647.11 EEB09665.2 - 0.13 12.3 34.6 0.19 11.8 11.8 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 EEB09665.2 - 0.16 10.5 9.5 0.21 10.1 9.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSBP1 PF06825.12 EEB09665.2 - 0.22 11.4 9.2 0.39 10.6 0.4 3.3 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF812 PF05667.11 EEB09665.2 - 0.26 10.1 35.1 0.41 9.5 35.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Vps5 PF09325.10 EEB09665.2 - 0.3 10.6 23.0 0.15 11.6 4.2 2.8 1 1 1 2 2 2 0 Vps5 C terminal like CLZ PF16526.5 EEB09665.2 - 0.36 11.2 30.3 0.7 10.3 4.0 4.0 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CREPT PF16566.5 EEB09665.2 - 0.39 10.9 26.7 1.2 9.3 12.9 3.1 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour KASH_CCD PF14662.6 EEB09665.2 - 0.4 10.5 36.5 0.19 11.5 33.0 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HemX PF04375.14 EEB09665.2 - 0.41 9.9 28.2 0.03 13.6 15.2 2.6 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase HrpB7 PF09486.10 EEB09665.2 - 0.44 10.9 29.0 0.6 10.5 15.2 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.11 EEB09665.2 - 0.46 10.8 15.8 17 5.8 3.7 3.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 EEB09665.2 - 0.46 10.6 28.4 1.1 9.4 10.0 3.5 3 0 0 3 3 3 0 bZIP transcription factor DUF3086 PF11285.8 EEB09665.2 - 0.46 9.5 14.2 2.1 7.4 14.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Cast PF10174.9 EEB09665.2 - 0.5 8.5 35.7 2.6 6.2 35.7 2.0 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DASH_Hsk3 PF08227.11 EEB09665.2 - 0.56 10.6 10.8 8.9 6.8 3.2 3.9 2 2 2 4 4 3 0 DASH complex subunit Hsk3 like DUF4795 PF16043.5 EEB09665.2 - 0.59 9.7 31.7 0.11 12.1 11.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 EEB09665.2 - 0.61 10.6 26.2 4.2 7.9 13.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.15 EEB09665.2 - 0.63 9.9 34.5 0.09 12.6 11.5 4.2 1 1 3 4 4 4 0 Septum formation initiator IFT57 PF10498.9 EEB09665.2 - 0.65 8.9 29.3 1.8 7.5 11.0 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 YlqD PF11068.8 EEB09665.2 - 0.72 10.2 26.0 0.036 14.4 17.4 2.5 1 1 2 3 3 3 0 YlqD protein YabA PF06156.13 EEB09665.2 - 0.75 10.5 27.4 1.9 9.2 8.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Leu_zip PF15294.6 EEB09665.2 - 0.75 9.3 32.0 57 3.1 6.4 1.9 1 1 0 1 1 1 0 Leucine zipper MPS2 PF17060.5 EEB09665.2 - 0.78 8.9 25.5 0.94 8.7 10.5 2.6 1 1 1 2 2 2 0 Monopolar spindle protein 2 Laminin_I PF06008.14 EEB09665.2 - 0.78 9.4 31.5 0.051 13.3 8.3 2.4 1 1 0 2 2 2 0 Laminin Domain I ApoO PF09769.9 EEB09665.2 - 0.79 9.7 12.3 0.67 9.9 3.6 3.0 1 1 2 3 3 3 0 Apolipoprotein O Sec34 PF04136.15 EEB09665.2 - 0.82 9.5 24.0 2.1 8.2 1.1 2.9 1 1 0 2 2 2 0 Sec34-like family Med9 PF07544.13 EEB09665.2 - 0.93 9.6 29.2 0.3 11.2 1.7 3.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spectrin PF00435.21 EEB09665.2 - 0.94 10.0 29.8 5.3 7.6 10.0 2.5 1 1 1 2 2 2 0 Spectrin repeat Fzo_mitofusin PF04799.13 EEB09665.2 - 0.98 9.0 19.2 0.67 9.5 5.6 2.2 1 1 1 2 2 2 0 fzo-like conserved region Allexi_40kDa PF05549.11 EEB09665.2 - 1 8.8 16.0 0.69 9.4 10.7 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein HAP1_N PF04849.13 EEB09665.2 - 1 8.5 37.8 1.5 7.9 37.8 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Uds1 PF15456.6 EEB09665.2 - 1 9.5 28.3 4.1 7.6 9.5 2.7 1 1 0 2 2 2 0 Up-regulated During Septation SlyX PF04102.12 EEB09665.2 - 1.1 9.9 28.0 3 8.5 9.6 3.9 1 1 3 4 4 4 0 SlyX Ax_dynein_light PF10211.9 EEB09665.2 - 1.1 9.1 35.6 0.77 9.7 6.7 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain Fib_alpha PF08702.10 EEB09665.2 - 1.2 9.4 23.8 1.1 9.4 13.4 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EEB09665.2 - 1.3 8.6 24.0 3.9 6.9 24.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit FemAB PF02388.16 EEB09665.2 - 1.4 7.7 28.2 1.2 8.0 7.0 2.0 1 1 1 2 2 2 0 FemAB family Flagellin_C PF00700.21 EEB09665.2 - 1.6 9.2 10.8 0.46 10.9 2.0 3.3 2 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region Jnk-SapK_ap_N PF09744.9 EEB09665.2 - 1.9 8.7 40.7 14 5.8 26.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 EEB09665.2 - 1.9 8.5 43.4 0.89 9.6 27.8 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Alanine_zipper PF11839.8 EEB09665.2 - 2 8.9 16.6 2.5 8.5 1.3 3.4 3 2 1 4 4 2 0 Alanine-zipper, major outer membrane lipoprotein GrpE PF01025.19 EEB09665.2 - 2 8.0 36.7 6 6.5 15.4 3.5 1 1 2 3 3 3 0 GrpE SHE3 PF17078.5 EEB09665.2 - 2 8.1 31.6 9.4 5.9 31.6 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Rho_Binding PF08912.11 EEB09665.2 - 2.2 9.2 39.6 1.6 9.6 2.2 4.1 1 1 3 4 4 4 0 Rho Binding OmpH PF03938.14 EEB09665.2 - 2.2 8.6 34.6 5.4 7.3 19.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Lectin_N PF03954.14 EEB09665.2 - 2.4 7.9 17.7 3.9 7.2 7.3 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.19 EEB09665.2 - 2.5 5.9 26.3 0.3 9.0 9.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HOOK PF05622.12 EEB09665.2 - 2.7 6.0 37.2 6.4 4.8 37.2 1.5 1 1 0 1 1 1 0 HOOK protein rRNA_proc-arch PF13234.6 EEB09665.2 - 2.7 7.8 26.1 0.3 11.0 2.7 3.1 1 1 3 4 4 4 0 rRNA-processing arch domain HSP70 PF00012.20 EEB09665.2 - 2.8 6.0 28.0 0.18 9.9 21.7 1.7 1 1 1 2 2 2 0 Hsp70 protein TMPIT PF07851.13 EEB09665.2 - 2.9 7.1 25.8 0.66 9.2 7.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein RmuC PF02646.16 EEB09665.2 - 3.3 6.8 24.4 2.7 7.0 10.2 3.0 1 1 2 3 3 3 0 RmuC family DUF1640 PF07798.11 EEB09665.2 - 3.3 7.7 32.9 6.4 6.8 11.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) RasGAP_C PF03836.15 EEB09665.2 - 3.6 7.7 22.1 23 5.1 16.9 2.9 1 1 1 2 2 2 0 RasGAP C-terminus Swi5 PF07061.11 EEB09665.2 - 3.8 7.7 35.2 2.1 8.5 5.4 4.0 1 1 3 4 4 4 0 Swi5 JIP_LZII PF16471.5 EEB09665.2 - 3.9 7.7 33.5 2.9 8.1 3.1 4.1 2 2 2 4 4 4 0 JNK-interacting protein leucine zipper II Dak2 PF02734.17 EEB09665.2 - 3.9 7.3 6.7 0.37 10.7 0.9 2.0 1 1 1 2 2 2 0 DAK2 domain DUF4446 PF14584.6 EEB09665.2 - 4.3 7.3 22.2 6.9 6.6 1.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4407 PF14362.6 EEB09665.2 - 4.6 6.5 25.4 8.5 5.6 25.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 EEB09665.2 - 5 7.5 30.6 22 5.4 4.4 3.2 1 1 0 2 2 2 0 Tup N-terminal Cob_adeno_trans PF01923.18 EEB09665.2 - 5.1 7.2 17.0 2.5 8.2 6.4 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4665 PF15679.5 EEB09665.2 - 5.2 7.8 16.1 6.4 7.5 8.9 2.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4665) DUF2968 PF11180.8 EEB09665.2 - 5.4 6.6 23.7 3.2 7.3 17.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Flagellin_N PF00669.20 EEB09665.2 - 5.4 7.1 11.2 2.1 8.5 4.2 2.5 1 1 2 3 3 2 0 Bacterial flagellin N-terminal helical region Prefoldin_2 PF01920.20 EEB09665.2 - 5.5 7.0 38.7 4 7.4 3.4 4.1 1 1 3 4 4 4 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 EEB09665.2 - 5.7 7.2 33.7 7.7 6.8 1.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 EEB09665.2 - 5.8 7.7 22.9 9.9 6.9 6.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Golgin_A5 PF09787.9 EEB09665.2 - 5.9 6.3 34.4 14 5.0 23.1 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 FlxA PF14282.6 EEB09665.2 - 6.4 6.8 28.5 6 6.9 18.4 3.2 1 1 2 3 3 3 0 FlxA-like protein ERM PF00769.19 EEB09665.2 - 6.4 6.5 42.1 1.3 8.8 13.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nsp1_C PF05064.13 EEB09665.2 - 6.8 6.5 25.7 0.82 9.5 11.4 2.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region Spc24 PF08286.11 EEB09665.2 - 7.3 6.9 36.5 1.7 8.9 7.6 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Lebercilin PF15619.6 EEB09665.2 - 7.6 6.1 40.5 4.3 7.0 15.9 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DegS PF05384.11 EEB09665.2 - 7.8 6.0 28.2 2.3 7.7 6.0 3.0 1 1 2 3 3 3 0 Sensor protein DegS BORCS7 PF16088.5 EEB09665.2 - 8 6.8 15.7 6.7 7.0 11.2 2.6 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 COG2 PF06148.11 EEB09665.2 - 8.2 6.5 24.4 3.6 7.7 6.2 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Med30 PF11315.8 EEB09665.2 - 8.4 6.6 25.6 2.1 8.5 8.1 3.2 1 1 2 3 3 3 0 Mediator complex subunit 30 DUF489 PF04356.12 EEB09665.2 - 9.2 6.2 13.4 4.2 7.3 4.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF489) Prominin PF05478.11 EEB09665.2 - 9.3 4.1 19.0 4.9 5.0 15.0 1.8 1 1 1 2 2 2 0 Prominin Herpes_UL6 PF01763.16 EEB09665.2 - 9.7 4.6 17.0 7.7 4.9 11.8 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like CorA PF01544.18 EEB09665.2 - 9.9 5.4 21.8 12 5.1 2.3 2.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Proteasome PF00227.26 EEB09666.1 - 5.6e-37 127.1 0.0 6.6e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Urocanase_N PF17391.2 EEB09666.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Urocanase N-terminal domain Inhibitor_I9 PF05922.16 EEB09667.1 - 0.018 15.7 0.0 0.031 14.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 Ribosomal_L10 PF00466.20 EEB09667.1 - 0.031 14.4 0.0 0.057 13.6 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L10 Trm112p PF03966.16 EEB09668.1 - 4.6e-20 72.0 0.1 5.6e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein CbeA_antitoxin PF06154.11 EEB09668.1 - 0.0098 16.5 0.2 2.8 8.6 0.1 2.1 1 1 1 2 2 2 2 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A eIF3m_C_helix PF18005.1 EEB09669.1 - 2.9e-09 36.5 1.1 7.3e-09 35.2 1.1 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 EEB09669.1 - 3.1e-08 34.1 0.1 3.1e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 PCI domain Na_Ca_ex PF01699.24 EEB09670.1 - 7.3e-47 159.1 46.1 1.1e-25 90.4 13.9 3.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein MRP-L27 PF09809.9 EEB09671.1 - 3.3e-11 43.0 0.3 3.8e-11 42.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RNA_pol_L_2 PF13656.6 EEB09672.1 - 1.3e-24 85.7 0.3 1.8e-24 85.3 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EEB09672.1 - 2.4e-08 33.3 0.0 3.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1410 PF07198.11 EEB09672.1 - 0.018 15.5 0.0 0.029 14.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) DUF4110 PF13422.6 EEB09673.1 - 0.18 11.9 0.0 25 5.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) UreD PF01774.17 EEB09674.1 - 1.7e-59 201.3 0.0 2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Ribosomal_L18A PF01775.17 EEB09675.1 - 9e-52 174.3 0.8 1.1e-51 174.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Torus PF16131.5 EEB09676.1 - 4.4e-41 140.0 0.2 4.4e-41 140.0 0.2 2.1 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 EEB09676.1 - 6.4e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EEB09676.1 - 0.00016 21.6 1.2 0.00028 20.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EEB09676.1 - 0.0044 17.0 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4130 PF13566.6 EEB09676.1 - 0.0075 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 zf-CCCH_4 PF18044.1 EEB09676.1 - 0.035 13.9 3.5 0.055 13.3 3.5 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger ATP11 PF06644.11 EEB09677.1 - 2.5e-56 191.5 5.1 3.5e-54 184.4 1.0 2.0 1 1 1 2 2 2 2 ATP11 protein APG17 PF04108.12 EEB09677.1 - 0.0053 15.9 0.4 0.0073 15.5 0.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 eIF3_subunit PF08597.10 EEB09678.1 - 1.8e-38 132.8 27.8 2.3e-38 132.5 27.8 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit EF-hand_1 PF00036.32 EEB09679.1 - 6.1e-39 128.7 6.6 1.6e-09 36.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EEB09679.1 - 1.6e-33 115.0 0.6 3.1e-16 59.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EEB09679.1 - 9.5e-31 105.4 6.8 2.1e-12 46.7 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EEB09679.1 - 4.3e-29 97.9 3.5 3.1e-09 36.0 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EEB09679.1 - 2.1e-24 83.9 7.9 2.8e-05 23.4 0.0 4.5 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 EEB09679.1 - 4.1e-15 55.8 0.1 1.8e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EEB09679.1 - 1e-08 35.1 1.0 0.0026 17.7 0.0 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EEB09679.1 - 1.4e-05 25.4 0.0 0.061 13.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 EEB09679.1 - 0.00021 21.3 0.2 0.00066 19.7 0.0 2.0 3 0 0 3 3 3 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 EEB09679.1 - 0.00033 21.4 0.2 1 10.2 0.0 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) TerB PF05099.13 EEB09679.1 - 0.00088 19.3 0.1 0.92 9.5 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EEB09679.1 - 0.0016 18.4 1.1 0.83 9.6 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 EEB09679.1 - 0.004 17.3 5.2 10 6.4 5.2 2.9 1 1 0 1 1 1 0 Dockerin type I domain PhageMin_Tail PF10145.9 EEB09679.1 - 0.027 14.3 0.4 0.059 13.2 0.2 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein DUF2267 PF10025.9 EEB09679.1 - 0.029 14.6 0.2 2.5 8.4 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF1103 PF06513.11 EEB09679.1 - 0.037 13.7 0.4 0.047 13.3 0.4 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) RTX_C PF08339.10 EEB09679.1 - 0.084 12.9 0.2 0.37 10.8 0.0 1.9 1 1 0 2 2 2 0 RTX C-terminal domain Acetyltransf_11 PF13720.6 EEB09679.1 - 0.14 12.6 0.0 4.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Vps53_N PF04100.12 EEB09680.1 - 4.5e-91 305.6 17.8 4.5e-91 305.6 17.8 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2451 PF10474.9 EEB09680.1 - 1.9e-05 24.6 0.2 7.6e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PhageMin_Tail PF10145.9 EEB09680.1 - 0.047 13.5 1.5 0.18 11.6 1.9 1.7 2 0 0 2 2 2 0 Phage-related minor tail protein SF3A3 PF16837.5 EEB09680.1 - 5.7 7.5 6.7 12 6.5 0.1 4.1 3 1 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 AA_permease PF00324.21 EEB09681.1 - 4.6e-104 348.7 35.1 4.6e-104 348.7 35.1 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 EEB09681.1 - 6.2e-33 114.3 36.9 8e-33 113.9 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease Thioredoxin_6 PF13848.6 EEB09682.1 - 3.5e-06 27.0 0.0 0.081 12.8 0.0 3.2 3 1 1 4 4 4 2 Thioredoxin-like domain YajC PF02699.15 EEB09682.1 - 0.17 11.8 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sugar_tr PF00083.24 EEB09683.1 - 3.5e-119 398.6 22.4 4.1e-119 398.4 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEB09683.1 - 5.8e-20 71.5 25.2 1.9e-14 53.4 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HECA PF15353.6 EEB09683.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 Headcase protein family homologue DUF4118 PF13493.6 EEB09683.1 - 3.2 7.6 9.4 0.23 11.3 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4118) Glyco_transf_15 PF01793.16 EEB09684.2 - 1.3e-33 116.7 8.9 1.7e-33 116.2 8.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sen15 PF09631.10 EEB09685.1 - 9e-25 86.9 0.0 1.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein TRA-1_regulated PF02343.16 EEB09685.1 - 0.069 13.2 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 BING4CT PF08149.11 EEB09686.1 - 5.8e-41 138.2 0.0 2.4e-37 126.6 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 EEB09686.1 - 5e-07 30.3 0.0 0.0037 18.1 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09686.1 - 1.2e-05 25.5 0.0 7.5 6.9 0.0 5.2 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEB09686.1 - 7.7e-05 21.9 0.0 0.00022 20.4 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region SNAP PF14938.6 EEB09687.1 - 6.9e-103 343.9 14.3 7.8e-103 343.8 14.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 EEB09687.1 - 0.41 11.6 11.3 1.7 9.6 0.5 4.7 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEB09687.1 - 0.71 10.0 7.4 9.1 6.6 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat FNIP_N PF14636.6 EEB09688.1 - 0.057 14.4 3.2 12 6.8 0.0 3.2 3 1 1 4 4 4 0 Folliculin-interacting protein N-terminus Maf1 PF09174.10 EEB09688.1 - 0.13 12.4 0.4 0.24 11.6 0.4 1.5 1 0 0 1 1 1 0 Maf1 regulator RRM_1 PF00076.22 EEB09689.1 - 2.4e-24 84.9 0.0 4.5e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEB09689.1 - 6.8e-09 35.4 0.0 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB09689.1 - 1.4e-05 24.9 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEB09689.1 - 0.0055 16.7 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EEB09689.1 - 0.016 15.5 0.5 4.6 7.4 0.0 2.9 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_8 PF11835.8 EEB09689.1 - 0.14 12.4 0.0 5.7 7.2 0.0 2.2 2 0 0 2 2 2 0 RRM-like domain ESCRT-II PF05871.12 EEB09690.1 - 1.7e-34 119.0 6.9 2e-34 118.8 6.9 1.0 1 0 0 1 1 1 1 ESCRT-II complex subunit FA_hydroxylase PF04116.13 EEB09691.2 - 9.8e-13 48.6 21.2 9.8e-13 48.6 21.2 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EEB09691.2 - 0.028 14.6 0.2 0.049 13.8 0.2 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 EEB09692.2 - 7.8e-38 128.1 0.1 5.9e-19 67.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EEB09692.2 - 1.7e-10 41.8 1.2 1.8e-06 28.9 0.1 2.7 1 1 1 2 2 2 2 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EEB09692.2 - 0.0004 20.2 0.0 0.55 10.1 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EEB09692.2 - 0.011 15.7 0.0 0.14 12.2 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 EEB09692.2 - 0.014 15.7 0.7 1.3 9.3 0.0 3.5 3 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EEB09692.2 - 0.049 13.8 0.0 3.8 7.7 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EEB09692.2 - 0.076 13.0 0.0 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3956 PF13104.6 EEB09692.2 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) EURL PF06937.11 EEB09692.2 - 0.14 11.6 0.8 1.3 8.3 0.3 2.5 3 0 0 3 3 3 0 EURL protein zf-RING_2 PF13639.6 EEB09693.1 - 1.1e-11 44.8 5.5 2.1e-11 44.0 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEB09693.1 - 1.8e-09 37.2 4.7 4.1e-09 36.0 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EEB09693.1 - 7.8e-08 32.2 3.3 1.5e-07 31.3 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEB09693.1 - 9.1e-08 32.3 4.2 2.1e-07 31.1 4.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EEB09693.1 - 4e-07 29.8 3.4 7.3e-07 28.9 3.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEB09693.1 - 4.3e-07 29.7 2.0 7.1e-07 29.0 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB09693.1 - 6.7e-07 29.1 5.2 1.3e-06 28.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEB09693.1 - 9.4e-07 28.6 4.4 1.9e-06 27.6 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB09693.1 - 1e-06 28.7 1.8 4.4e-06 26.6 0.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEB09693.1 - 0.00017 21.6 3.7 0.0021 18.1 3.7 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EEB09693.1 - 0.00056 19.5 3.5 0.0011 18.5 3.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EEB09693.1 - 0.024 14.7 2.3 0.033 14.3 1.0 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 EEB09693.1 - 0.026 14.4 2.6 0.054 13.4 2.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EEB09693.1 - 0.046 13.5 3.2 0.097 12.5 3.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 EEB09693.1 - 0.068 12.5 0.6 0.2 11.0 0.4 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger Vps39_2 PF10367.9 EEB09693.1 - 0.073 13.5 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 EEB09693.1 - 0.078 13.3 1.5 0.21 11.9 1.5 1.7 1 0 0 1 1 1 0 RING-like domain EI24 PF07264.11 EEB09693.1 - 0.082 13.2 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF5345 PF17280.2 EEB09693.1 - 0.083 12.9 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) RINGv PF12906.7 EEB09693.1 - 0.36 11.0 4.0 0.85 9.8 4.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 EEB09693.1 - 0.8 9.9 5.1 4.5 7.5 5.2 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EEB09693.1 - 1.3 9.2 6.3 15 5.8 6.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RNase_P_p30 PF01876.16 EEB09694.1 - 9.9e-64 214.7 0.0 1.2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit p30 pKID PF02173.17 EEB09694.1 - 0.0027 17.1 0.7 0.039 13.4 0.5 2.3 2 0 0 2 2 2 1 pKID domain Arnt_C PF18583.1 EEB09694.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Peptidase_M1_N PF17900.1 EEB09695.1 - 5.1e-08 33.3 0.0 1.5e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EEB09695.1 - 0.0012 18.5 0.1 0.0027 17.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain Imm39 PF15568.6 EEB09695.1 - 0.0098 16.0 0.1 0.097 12.8 0.0 2.2 2 0 0 2 2 2 1 Immunity protein 39 RNase_E_G PF10150.9 EEB09695.1 - 0.08 12.3 0.8 5.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease E/G family Ntox28 PF15605.6 EEB09695.1 - 0.14 12.4 0.1 0.47 10.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial toxin 28 Ribosomal_S19 PF00203.21 EEB09696.1 - 5e-27 93.6 0.1 6.1e-27 93.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Med29 PF11568.8 EEB09697.1 - 0.044 14.0 0.3 0.068 13.4 0.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 Gti1_Pac2 PF09729.9 EEB09698.1 - 4.2e-47 160.6 3.5 1.2e-38 133.1 0.2 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family WD40 PF00400.32 EEB09699.1 - 8.1e-63 206.9 9.7 2e-10 41.0 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EEB09699.1 - 2.2e-22 79.2 6.8 3.5e-22 78.5 6.8 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EEB09699.1 - 3.5e-21 75.3 0.3 0.0016 18.7 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB09699.1 - 1.6e-12 47.1 0.4 0.19 10.7 0.0 5.7 1 1 4 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEB09699.1 - 1.6e-08 34.2 0.1 0.0077 15.6 0.0 5.1 4 1 1 5 5 5 2 WD40-like domain PD40 PF07676.12 EEB09699.1 - 3.7e-08 33.1 0.0 2.5 8.2 0.0 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EEB09699.1 - 9e-06 25.7 0.0 0.012 15.5 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEB09699.1 - 0.0038 15.9 0.1 0.94 8.0 0.0 3.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 DUF4472 PF14739.6 EEB09699.1 - 0.0042 17.8 0.5 0.013 16.2 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) Cytochrom_D1 PF02239.16 EEB09699.1 - 0.022 13.3 0.7 0.051 12.1 0.3 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 EEB09699.1 - 0.037 13.1 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Nbas_N PF15492.6 EEB09699.1 - 0.04 13.3 0.7 16 4.7 0.0 3.7 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal nos_propeller PF18764.1 EEB09699.1 - 0.058 13.3 0.1 2.7 8.0 0.0 3.4 2 2 1 3 3 3 0 Nitrous oxide reductase propeller repeat SOG2 PF10428.9 EEB09699.1 - 0.71 9.0 18.7 1 8.5 18.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF919 PF06034.11 EEB09699.1 - 4.5 7.2 6.4 10 6.0 6.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF5122 PF17164.4 EEB09699.1 - 9.5 6.6 7.5 40 4.6 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller PPTA PF01239.22 EEB09701.1 - 3.4e-36 121.9 20.8 1.5e-10 40.5 0.4 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 EEB09701.1 - 0.00085 18.9 3.7 0.087 12.5 0.4 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4219) TPR_9 PF13371.6 EEB09701.1 - 0.012 15.8 0.3 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.28 EEB09702.1 - 1.3e-12 48.6 0.2 2.2e-12 47.9 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3384 PF11864.8 EEB09703.2 - 1.5e-79 268.1 13.5 1.5e-79 268.1 13.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EEB09703.2 - 4.1e-49 166.7 0.0 8.7e-49 165.6 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EEB09703.2 - 9.4e-16 57.9 16.6 3.9e-14 52.5 6.4 3.8 2 1 1 3 3 3 2 Tuberin DUF5427 PF10310.9 EEB09703.2 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5427) IU_nuc_hydro PF01156.19 EEB09704.2 - 3.7e-43 148.2 0.0 4.4e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S8 PF00082.22 EEB09705.1 - 1.8e-68 231.0 0.3 2.7e-68 230.4 0.3 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 EEB09705.1 - 1.7e-53 181.0 0.0 3.4e-53 180.0 0.0 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II SLS PF14611.6 EEB09706.2 - 1.4e-19 70.9 0.4 2.2e-19 70.2 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Rho_N PF07498.12 EEB09706.2 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Adap_comp_sub PF00928.21 EEB09708.1 - 2.7e-40 138.4 0.4 5.2e-40 137.5 0.4 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MMS22L_C PF14911.6 EEB09708.1 - 0.053 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Plus-3 PF03126.18 EEB09710.1 - 2.4e-31 108.5 0.7 6.3e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain FapA PF03961.13 EEB09710.1 - 2.6 6.6 17.0 0.17 10.4 7.8 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A RNA_pol_Rpb1_1 PF04997.12 EEB09711.1 - 3e-90 302.7 0.0 4.9e-90 302.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EEB09711.1 - 7.6e-79 264.9 0.2 1.1e-78 264.4 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEB09711.1 - 1.9e-73 246.2 0.0 3.4e-73 245.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEB09711.1 - 2.8e-40 137.8 0.0 6.3e-40 136.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEB09711.1 - 7.9e-32 109.4 0.1 1.7e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 BppL_N PF18338.1 EEB09711.1 - 0.31 10.9 1.2 1.5 8.7 0.3 2.6 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain zinc-ribbons_6 PF07191.12 EEB09711.1 - 6.6 6.8 6.5 2.4 8.2 2.6 2.2 2 0 0 2 2 2 0 zinc-ribbons DUF713 PF05218.14 EEB09713.1 - 0.046 13.4 1.2 0.47 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DUF3770 PF12603.8 EEB09713.1 - 0.11 12.0 1.3 0.14 11.6 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3770) Cep57_CLD_2 PF14197.6 EEB09713.1 - 2.2 8.4 7.2 3 8.0 0.8 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 EAP30 PF04157.16 EEB09714.1 - 1.6e-51 174.9 0.8 1.7e-51 174.8 0.8 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 EEB09714.1 - 0.007 16.3 0.8 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Tex_N PF09371.10 EEB09714.1 - 0.041 13.6 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain RabGAP-TBC PF00566.18 EEB09716.1 - 1.5e-26 93.4 2.3 2e-26 93.0 2.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CN_hydrolase PF00795.22 EEB09717.1 - 5.1e-55 186.6 0.0 5.8e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NOG1_N PF17835.1 EEB09718.1 - 3.6e-51 173.3 0.9 3.6e-51 173.3 0.9 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EEB09718.1 - 1.8e-27 95.1 0.2 5.4e-27 93.5 0.2 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EEB09718.1 - 1.8e-26 91.7 0.3 3.9e-26 90.6 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EEB09718.1 - 1.9e-17 63.4 0.0 5.6e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB09718.1 - 5.5e-10 39.0 0.1 1.2e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEB09718.1 - 0.0018 18.2 0.7 0.65 9.9 0.0 3.7 4 1 0 4 4 4 1 RsgA GTPase AIG1 PF04548.16 EEB09718.1 - 0.002 17.5 0.0 0.002 17.5 0.0 2.4 3 0 0 3 3 3 1 AIG1 family AAA_16 PF13191.6 EEB09718.1 - 0.0036 17.7 2.8 0.44 10.9 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.23 EEB09718.1 - 0.015 15.4 4.5 0.88 9.6 0.0 3.0 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 EEB09718.1 - 0.039 14.2 1.2 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EEB09718.1 - 0.065 13.8 1.7 6.3 7.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 EEB09719.1 - 3.1e-07 30.1 0.0 8.2e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EEB09719.1 - 9e-06 26.4 0.0 2.7e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Flu_PB1 PF00602.17 EEB09719.1 - 0.073 11.2 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Coprogen_oxidas PF01218.18 EEB09721.1 - 8.9e-132 438.3 0.7 1e-131 438.1 0.7 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PAP_assoc PF03828.19 EEB09722.1 - 9.3e-16 57.8 0.2 2.1e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EEB09722.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEB09722.1 - 0.009 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase FANCI_S4 PF14678.6 EEB09724.1 - 0.027 13.6 0.2 0.23 10.6 0.1 2.0 2 0 0 2 2 2 0 FANCI solenoid 4 RRM_1 PF00076.22 EEB09725.1 - 7.5e-14 51.3 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEB09725.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TBPIP PF07106.13 EEB09726.1 - 5.3e-24 83.9 2.2 1.6e-23 82.4 0.2 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 EEB09726.1 - 0.0028 18.0 0.9 0.0079 16.5 0.5 2.0 1 1 0 1 1 1 1 Penicillinase repressor HTH_20 PF12840.7 EEB09726.1 - 0.006 16.6 0.0 0.018 15.1 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain CTP_transf_3 PF02348.19 EEB09726.1 - 0.018 15.0 1.4 0.023 14.6 1.4 1.2 1 0 0 1 1 1 0 Cytidylyltransferase DUF3450 PF11932.8 EEB09726.1 - 0.018 14.4 6.1 0.027 13.8 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IES5 PF17335.2 EEB09726.1 - 0.027 14.7 5.5 0.077 13.3 5.5 1.8 1 1 0 1 1 1 0 Ino80 complex subunit 5 Prefoldin_2 PF01920.20 EEB09726.1 - 0.051 13.5 11.6 1.1 9.2 3.4 2.5 1 1 1 2 2 2 0 Prefoldin subunit LMWPc PF01451.21 EEB09726.1 - 0.062 13.7 1.1 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Atg14 PF10186.9 EEB09726.1 - 0.11 11.6 5.7 0.17 11.0 5.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EEB09726.1 - 0.11 11.1 5.9 0.13 10.9 5.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rrf2 PF02082.20 EEB09726.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HalX PF08663.10 EEB09726.1 - 0.12 12.7 4.6 1.5 9.2 1.1 2.7 2 0 0 2 2 2 0 HalX domain FlxA PF14282.6 EEB09726.1 - 0.14 12.1 6.5 1 9.4 6.5 2.2 1 1 0 1 1 1 0 FlxA-like protein Snapin_Pallidin PF14712.6 EEB09726.1 - 0.15 12.5 9.7 0.09 13.2 4.0 2.6 1 1 1 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 EEB09726.1 - 0.17 12.1 11.5 0.26 11.5 5.7 3.1 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 EEB09726.1 - 0.18 11.9 12.9 0.4 10.7 12.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Dad2 PF08654.10 EEB09726.1 - 0.24 11.8 6.3 0.52 10.8 3.5 2.4 2 1 0 2 2 1 0 DASH complex subunit Dad2 DivIC PF04977.15 EEB09726.1 - 0.31 10.8 7.4 1.7 8.5 0.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Linker_histone PF00538.19 EEB09726.1 - 0.46 10.9 3.4 0.95 9.9 0.2 2.5 2 1 1 3 3 2 0 linker histone H1 and H5 family XhlA PF10779.9 EEB09726.1 - 0.51 10.6 5.2 0.78 10.0 0.4 2.5 2 0 0 2 2 2 0 Haemolysin XhlA PEP-utilisers_N PF05524.13 EEB09726.1 - 0.55 10.4 4.6 3.1 8.0 2.2 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal MPS2 PF17060.5 EEB09726.1 - 0.56 9.4 8.6 1.1 8.5 7.6 1.9 1 1 0 1 1 1 0 Monopolar spindle protein 2 YabA PF06156.13 EEB09726.1 - 0.57 10.9 9.8 2.3 8.9 8.8 2.3 1 1 0 1 1 1 0 Initiation control protein YabA CorA PF01544.18 EEB09726.1 - 0.8 9.0 4.4 0.72 9.1 0.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 EEB09726.1 - 0.83 10.1 4.7 1.1 9.7 0.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 EEB09726.1 - 1.3 9.3 10.9 7.2 6.9 1.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 eIF3_N PF09440.10 EEB09726.1 - 1.3 9.4 9.6 0.38 11.2 3.7 2.5 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain NPV_P10 PF05531.12 EEB09726.1 - 2 8.9 4.7 3.5 8.2 2.0 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 EEB09726.1 - 2.3 7.0 4.4 2.5 6.9 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EEB09726.1 - 3.1 7.1 7.1 6.8 5.9 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 EEB09726.1 - 3.2 8.2 11.4 0.79 10.2 7.0 1.9 1 1 1 2 2 2 0 AAA domain Syntaxin-6_N PF09177.11 EEB09726.1 - 5.2 7.7 8.8 85 3.8 8.8 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ALG3 PF05208.13 EEB09727.1 - 1.2e-121 406.6 27.5 1.3e-121 406.4 27.5 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4462 PF14692.6 EEB09727.1 - 0.089 12.3 0.2 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Thioredoxin PF00085.20 EEB09728.1 - 3.7e-30 104.0 0.4 4.1e-30 103.8 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEB09728.1 - 1.3e-06 28.9 0.4 3.2e-05 24.3 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEB09728.1 - 6.5e-06 26.4 0.0 0.00014 22.1 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EEB09728.1 - 5.8e-05 23.0 0.1 6.6e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EEB09728.1 - 0.00041 20.1 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EEB09728.1 - 0.00048 19.6 0.1 0.00054 19.4 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EEB09728.1 - 0.0029 17.3 0.2 0.005 16.6 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EEB09728.1 - 0.05 13.8 0.2 0.078 13.2 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Ost4 PF10215.9 EEB09729.1 - 7.5e-12 44.9 3.4 8.5e-12 44.7 3.4 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase Steroid_dh PF02544.16 EEB09730.1 - 6.4e-13 48.9 4.6 6.4e-13 48.9 4.6 2.2 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase V-ATPase_H_N PF03224.14 EEB09731.1 - 8.5e-52 176.4 6.6 1.9e-51 175.3 5.0 2.3 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EEB09731.1 - 2.7e-43 146.8 1.3 8.8e-42 141.9 0.1 3.3 4 0 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.22 EEB09731.1 - 8.7e-06 25.6 1.8 0.036 14.3 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 EEB09731.1 - 3e-05 23.9 0.1 0.00076 19.4 0.0 3.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EEB09731.1 - 0.00032 20.3 0.6 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 EEB09731.1 - 0.0077 16.6 0.0 0.14 12.6 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats GP4 PF03010.14 EEB09731.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 GP4 Sec39 PF08314.11 EEB09732.1 - 2.4e-42 145.4 16.4 5.3e-42 144.2 16.4 1.5 1 1 0 1 1 1 1 Secretory pathway protein Sec39 ThrE PF06738.12 EEB09733.1 - 1.8e-60 204.3 18.6 7.1e-59 199.1 5.6 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EEB09733.1 - 7.1e-07 29.4 13.0 7.1e-07 29.4 13.0 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE PPR_2 PF13041.6 EEB09734.2 - 0.024 14.8 0.1 3.7 7.8 0.0 3.4 4 0 0 4 4 4 0 PPR repeat family APOBEC_N PF08210.11 EEB09734.2 - 0.06 13.2 1.4 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 APOBEC-like N-terminal domain PPR PF01535.20 EEB09734.2 - 0.12 12.7 0.1 21 5.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.7 EEB09734.2 - 0.13 12.0 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat PPR_long PF17177.4 EEB09734.2 - 0.21 10.9 1.6 8.7 5.6 0.4 3.0 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Exo70 PF03081.15 EEB09735.1 - 4.8e-48 164.1 3.4 4.8e-48 164.1 3.4 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit GAS PF13851.6 EEB09735.1 - 0.0065 15.8 0.9 0.0065 15.8 0.9 2.4 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EEB09735.1 - 0.019 15.0 4.1 0.25 11.3 0.6 2.8 1 1 1 2 2 2 0 Laminin Domain II BAR PF03114.18 EEB09735.1 - 0.028 14.1 2.0 0.041 13.5 0.4 2.0 2 0 0 2 2 2 0 BAR domain Seryl_tRNA_N PF02403.22 EEB09735.1 - 0.12 12.7 0.8 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LOH1CR12 PF10158.9 EEB09735.1 - 0.4 10.7 4.7 4.6 7.3 0.6 3.3 3 1 0 3 3 3 0 Tumour suppressor protein TACC_C PF05010.14 EEB09735.1 - 0.54 10.0 4.5 0.42 10.4 0.3 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal XhlA PF10779.9 EEB09735.1 - 0.96 9.7 6.9 1.2 9.4 0.1 3.9 5 0 0 5 5 5 0 Haemolysin XhlA HTH_WhiA PF02650.14 EEB09735.1 - 1.9 8.9 5.6 3 8.2 0.2 3.1 2 1 1 3 3 3 0 WhiA C-terminal HTH domain Baculo_PEP_C PF04513.12 EEB09735.1 - 2.4 8.2 12.8 2.1 8.4 4.8 3.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 EEB09735.1 - 3.2 8.5 5.8 25 5.7 0.0 3.7 2 2 2 4 4 4 0 Occludin homology domain COG5 PF10392.9 EEB09735.1 - 3.9 7.7 9.4 3.8 7.7 1.1 4.0 3 1 1 4 4 4 0 Golgi transport complex subunit 5 LXG PF04740.12 EEB09735.1 - 4.2 7.0 6.7 2.6 7.7 2.0 2.9 2 2 0 2 2 2 0 LXG domain of WXG superfamily DUF5553 PF17707.1 EEB09736.2 - 0.064 12.7 0.6 0.14 11.6 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5553) WD40 PF00400.32 EEB09737.1 - 4e-13 49.6 2.5 0.00083 20.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09737.1 - 4.4e-08 33.3 0.0 0.013 15.8 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB09737.1 - 0.016 14.2 0.0 0.91 8.4 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EEB09737.1 - 0.1 11.8 0.1 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller HAD PF12710.7 EEB09738.1 - 2e-23 83.8 0.0 2.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EEB09738.1 - 2.8e-06 26.9 0.1 1.7e-05 24.3 0.1 2.1 1 1 1 2 2 2 1 Putative Phosphatase FF PF01846.19 EEB09738.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 FF domain She9_MDM33 PF05546.11 EEB09739.1 - 5.4e-72 241.8 12.2 6.6e-72 241.5 11.6 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family DUF4559 PF15112.6 EEB09739.1 - 0.00043 20.1 6.1 0.00043 20.1 6.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4559) PsbH PF00737.20 EEB09739.1 - 0.29 10.9 0.2 0.29 10.9 0.2 1.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein GTSE1_N PF15259.6 EEB09739.1 - 0.6 10.3 7.2 0.04 14.1 2.1 1.7 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Thioredoxin_4 PF13462.6 EEB09739.1 - 1.1 9.4 4.3 0.53 10.4 1.6 1.7 2 0 0 2 2 2 0 Thioredoxin DRY_EERY PF09750.9 EEB09739.1 - 4.2 7.7 9.2 0.82 9.9 4.5 2.0 2 0 0 2 2 2 0 Alternative splicing regulator Clathrin PF00637.20 EEB09740.1 - 5.1e-10 39.4 5.6 1.4e-09 38.0 1.0 2.9 2 1 1 3 3 3 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EEB09740.1 - 3.7e-07 30.1 12.4 1.3e-06 28.4 12.4 2.0 1 0 0 1 1 1 1 Zinc-finger PPR_1 PF12854.7 EEB09740.1 - 0.0045 16.7 1.2 2.9 7.7 0.0 2.9 2 0 0 2 2 2 2 PPR repeat PPR PF01535.20 EEB09740.1 - 0.029 14.6 8.9 10 6.6 0.2 5.8 6 0 0 6 6 6 0 PPR repeat PPR_2 PF13041.6 EEB09740.1 - 0.038 14.2 3.3 5.9 7.2 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family TPR_14 PF13428.6 EEB09740.1 - 0.19 12.6 0.3 2.6 9.1 0.0 3.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09740.1 - 0.39 11.3 2.3 65 4.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 EEB09740.1 - 0.56 9.7 2.5 21 4.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EEB09740.1 - 0.68 10.0 3.2 1.4 9.0 3.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon ANAPC3 PF12895.7 EEB09740.1 - 0.71 10.1 6.4 12 6.2 0.1 4.7 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-rbx1 PF12678.7 EEB09740.1 - 3.8 7.9 11.5 2.2 8.6 8.6 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain LRR_4 PF12799.7 EEB09742.2 - 1.3e-32 111.3 48.6 3e-08 33.8 0.9 6.7 2 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EEB09742.2 - 2.5e-20 72.7 20.9 1.2e-08 34.7 6.0 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 EEB09742.2 - 2.5e-17 62.4 43.3 1.7e-06 27.7 3.0 5.9 3 2 3 7 7 7 5 Leucine rich repeat DUF2322 PF10084.9 EEB09742.2 - 0.0011 19.0 3.6 20 5.3 0.0 4.7 2 2 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_6 PF13516.6 EEB09742.2 - 0.0084 16.1 30.7 1.2 9.4 0.3 8.1 8 0 0 8 8 8 3 Leucine Rich repeat CITED PF04487.12 EEB09742.2 - 0.017 15.2 1.7 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 CITED FNIP PF05725.12 EEB09742.2 - 0.053 13.7 3.8 2 8.7 0.0 4.5 2 1 2 4 4 4 0 FNIP Repeat LRR_1 PF00560.33 EEB09742.2 - 0.13 12.9 39.0 0.71 10.6 0.4 10.0 7 3 1 8 8 8 0 Leucine Rich Repeat DUF1492 PF07374.11 EEB09742.2 - 0.2 11.8 1.4 0.52 10.5 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) RTBV_P12 PF06361.11 EEB09742.2 - 0.59 10.6 5.4 4.9 7.6 0.8 2.7 2 1 1 3 3 3 0 Rice tungro bacilliform virus P12 protein Proteasome PF00227.26 EEB09743.2 - 9e-46 155.8 0.1 1.1e-45 155.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pribosyltran_N PF13793.6 EEB09744.2 - 7.3e-42 142.0 0.0 1.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEB09744.2 - 1.9e-06 28.0 0.1 2.4e-05 24.5 0.0 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Acyl-CoA_dh_M PF02770.19 EEB09744.2 - 0.054 13.7 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Pribosyltran PF00156.27 EEB09744.2 - 0.11 12.0 0.0 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase domain SPA PF08616.10 EEB09744.2 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Mus7 PF09462.10 EEB09745.1 - 8.7e-99 332.1 24.2 8.7e-99 332.1 24.2 2.0 2 0 0 2 2 2 1 Mus7/MMS22 family FAS_I_H PF18314.1 EEB09746.1 - 5.6e-76 254.7 0.0 1e-75 253.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EEB09746.1 - 1e-73 247.0 0.6 2.3e-73 245.9 0.1 1.9 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EEB09746.1 - 4.3e-22 78.9 0.0 7.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EEB09746.1 - 3.2e-17 62.7 0.0 7.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EEB09746.1 - 9.5e-11 41.8 0.0 3.1e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EEB09746.1 - 2.2e-09 37.1 0.0 8.6e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEB09746.1 - 4.5e-06 26.4 0.5 5.3e-05 22.9 0.0 3.0 5 0 0 5 5 5 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEB09746.1 - 0.00053 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.23 EEB09746.1 - 0.032 13.6 1.0 0.081 12.3 0.4 1.9 1 1 1 2 2 2 0 Thiolase, N-terminal domain DEC-1_N PF04625.13 EEB09746.1 - 2 7.4 8.6 3.4 6.6 8.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF676 PF05057.14 EEB09747.1 - 4.6e-53 180.0 0.0 7.2e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EEB09747.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 EEB09747.1 - 0.18 12.4 2.1 0.21 12.2 0.1 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family cwf21 PF08312.12 EEB09748.2 - 2.9e-13 49.7 2.6 6e-13 48.7 2.6 1.6 1 0 0 1 1 1 1 cwf21 domain FeoB_Cyto PF17910.1 EEB09748.2 - 0.069 13.7 0.7 0.13 12.8 0.7 1.5 1 0 0 1 1 1 0 FeoB cytosolic helical domain DUF2407_C PF13373.6 EEB09748.2 - 0.33 11.1 4.2 0.73 10.0 4.2 1.7 1 1 0 1 1 1 0 DUF2407 C-terminal domain DEAD PF00270.29 EEB09749.2 - 2.7e-47 160.8 0.0 4.6e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEB09749.2 - 2.9e-30 104.8 0.2 9.4e-30 103.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEB09749.2 - 1.3e-07 31.8 0.0 2.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEB09749.2 - 0.0011 18.7 0.0 0.0033 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain Per1 PF04080.13 EEB09750.1 - 8e-96 320.7 16.0 1e-95 320.3 16.0 1.1 1 0 0 1 1 1 1 Per1-like family Bromo_TP PF07524.13 EEB09752.1 - 4.3e-18 65.1 0.3 6.8e-18 64.5 0.3 1.3 1 0 0 1 1 1 1 Bromodomain associated SNARE PF05739.19 EEB09753.1 - 6.1e-17 61.4 0.2 6.1e-17 61.4 0.2 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EEB09753.1 - 0.00081 19.7 12.0 0.19 12.1 5.9 2.5 2 1 0 2 2 2 2 Syntaxin-like protein MCPsignal PF00015.21 EEB09753.1 - 0.0031 17.4 6.6 0.19 11.5 1.2 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain GRAS PF03514.14 EEB09753.1 - 0.0074 15.3 0.2 0.013 14.5 0.2 1.3 1 0 0 1 1 1 1 GRAS domain family Cor1 PF04803.12 EEB09753.1 - 0.02 15.1 1.7 0.02 15.1 1.7 2.7 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF16 PF01519.16 EEB09753.1 - 0.067 13.7 0.7 0.067 13.7 0.7 2.6 1 1 0 2 2 2 0 Protein of unknown function DUF16 CrgA PF06781.12 EEB09753.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA COG5 PF10392.9 EEB09753.1 - 0.16 12.1 3.6 1.8 8.8 0.3 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Fib_alpha PF08702.10 EEB09753.1 - 0.58 10.3 7.3 7.8 6.7 1.5 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2116 PF09889.9 EEB09753.1 - 1.6 8.8 4.4 4.2 7.4 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMPIT PF07851.13 EEB09753.1 - 3.9 6.6 10.1 1.1 8.4 1.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein RRP36 PF06102.12 EEB09754.2 - 1.2e-52 178.3 28.7 1.2e-52 178.3 28.7 2.6 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 RB_A PF01858.17 EEB09754.2 - 5.7 6.7 12.8 1.8 8.4 4.5 2.3 2 1 0 2 2 2 0 Retinoblastoma-associated protein A domain Pkinase PF00069.25 EEB09755.1 - 1e-50 172.6 0.3 3.1e-50 171.0 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEB09755.1 - 1.1e-20 74.0 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEB09755.1 - 0.00057 19.9 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEB09755.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EEB09755.1 - 0.043 13.2 0.9 1.3 8.3 0.1 2.6 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EEB09755.1 - 0.07 12.7 0.6 0.16 11.5 0.3 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase eIF-3c_N PF05470.12 EEB09757.1 - 1.4e-211 703.9 14.5 1.4e-211 703.9 14.5 3.7 2 2 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EEB09757.1 - 3.3e-13 50.0 0.0 1.9e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain Prominin PF05478.11 EEB09757.1 - 0.031 12.2 0.2 0.06 11.3 0.2 1.4 1 0 0 1 1 1 0 Prominin Sigma70_r4 PF04545.16 EEB09757.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Ribosomal_L10 PF00466.20 EEB09757.1 - 0.1 12.8 1.5 6.3 7.0 0.1 3.7 4 0 0 4 4 4 0 Ribosomal protein L10 DUF2701 PF10857.8 EEB09757.1 - 0.14 12.2 0.2 0.77 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) Macoilin PF09726.9 EEB09757.1 - 5.7 5.4 29.0 12 4.3 29.0 1.5 1 0 0 1 1 1 0 Macoilin family Profilin PF00235.19 EEB09758.1 - 5.2e-45 152.8 0.0 5.7e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Profilin LysM PF01476.20 EEB09758.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain MFS_1 PF07690.16 EEB09759.1 - 8.1e-40 136.8 58.8 8.1e-40 136.8 58.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEB09759.1 - 6.3e-15 54.6 27.1 8.1e-15 54.2 27.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEB09759.1 - 8.2e-15 54.6 8.9 8.2e-15 54.6 8.9 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2675 PF11247.8 EEB09759.1 - 0.14 12.3 0.1 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) Neurensin PF14927.6 EEB09759.1 - 2.6 7.8 6.1 2 8.2 0.4 3.4 3 2 0 3 3 3 0 Neurensin Mito_carr PF00153.27 EEB09760.1 - 1.2e-54 182.2 0.9 2.2e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEB09760.1 - 0.07 12.3 0.4 2.9 7.0 0.0 2.5 2 2 0 2 2 2 0 Gammaproteobacterial serine protease Ank_4 PF13637.6 EEB09761.2 - 0.051 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Asparaginase_2 PF01112.18 EEB09762.2 - 3.1e-47 161.1 0.0 4.1e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase DUF3932 PF13068.6 EEB09762.2 - 0.046 14.0 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) PAP2 PF01569.21 EEB09763.1 - 1.4e-17 63.7 8.4 1.4e-17 63.7 8.4 3.1 2 2 1 3 3 3 1 PAP2 superfamily DUF1196 PF06709.11 EEB09763.1 - 0.085 13.0 0.4 0.18 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) PAP2_3 PF14378.6 EEB09763.1 - 8.4 6.0 15.5 2 8.1 10.9 2.4 2 1 0 2 2 2 0 PAP2 superfamily HbrB PF08539.11 EEB09764.2 - 9.7e-22 77.7 2.7 9.7e-22 77.7 2.7 1.7 2 0 0 2 2 2 1 HbrB-like Aminotran_1_2 PF00155.21 EEB09765.1 - 1.7e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEB09765.1 - 0.004 15.8 0.0 0.0075 14.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEB09765.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EEB09765.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EEB09765.1 - 0.034 13.1 0.0 0.49 9.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V PAPA-1 PF04795.12 EEB09766.1 - 6.1e-24 84.6 7.2 6.1e-24 84.6 7.2 3.6 3 1 0 3 3 3 2 PAPA-1-like conserved region DUF5542 PF17696.1 EEB09766.1 - 5.5 7.2 5.1 2.8 8.1 2.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5542) SPX PF03105.19 EEB09767.1 - 5.9e-47 161.4 2.9 3.1e-45 155.8 2.9 2.2 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EEB09767.1 - 1.3e-06 28.1 8.6 1.3e-06 28.1 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEB09767.1 - 2.1e-06 27.8 10.5 2.1e-06 27.8 10.5 2.8 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EEB09767.1 - 2.6e-06 27.7 10.5 2.6e-06 27.7 10.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EEB09767.1 - 1.9e-05 24.4 10.6 1.9e-05 24.4 10.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEB09767.1 - 2e-05 24.4 10.4 2e-05 24.4 10.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEB09767.1 - 0.00012 22.0 11.0 0.0005 20.0 11.0 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEB09767.1 - 0.004 17.1 11.6 0.004 17.1 11.6 3.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEB09767.1 - 0.0051 17.1 5.9 0.0051 17.1 5.9 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEB09767.1 - 0.014 15.4 3.7 0.026 14.6 2.0 2.4 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EEB09767.1 - 0.015 15.2 9.7 0.015 15.2 9.7 2.2 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 NOB1_Zn_bind PF08772.11 EEB09767.1 - 1.4 9.1 6.7 0.12 12.5 1.4 2.1 2 0 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like MbeD_MobD PF04899.12 EEB09767.1 - 2.1 8.5 7.3 1.1 9.5 0.5 3.0 3 1 0 3 3 2 0 MbeD/MobD like zf-RING_4 PF14570.6 EEB09767.1 - 6.3 6.7 15.0 0.035 13.9 3.7 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 EEB09767.1 - 8.6 6.5 11.7 8.9 6.4 5.8 3.2 2 1 0 2 2 2 0 Transposase zinc-binding domain DnaJ PF00226.31 EEB09768.1 - 3.1e-20 72.1 0.0 1.3e-19 70.1 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EEB09768.1 - 1.8e-09 37.7 4.8 4.9e-09 36.2 4.8 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEB09768.1 - 1.8e-06 28.2 5.1 4.3e-06 26.9 5.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF4230 PF14014.6 EEB09768.1 - 0.0018 18.6 3.8 0.094 13.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4230) zf-C2H2_4 PF13894.6 EEB09768.1 - 0.0032 18.2 4.8 0.0041 17.9 3.1 2.2 2 0 0 2 2 1 1 C2H2-type zinc finger CpXC PF14353.6 EEB09768.1 - 0.0033 17.5 1.1 0.012 15.7 1.1 1.9 1 0 0 1 1 1 1 CpXC protein zf-C2H2_2 PF12756.7 EEB09768.1 - 0.0056 17.0 4.7 0.017 15.4 4.7 1.9 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EEB09768.1 - 0.016 15.6 6.8 0.019 15.4 5.3 2.0 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 EEB09768.1 - 0.074 12.7 3.7 0.22 11.2 3.7 1.9 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain HscB_4_cys PF18256.1 EEB09768.1 - 0.091 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-FPG_IleRS PF06827.14 EEB09768.1 - 0.13 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2H2_6 PF13912.6 EEB09768.1 - 0.2 11.7 4.2 0.63 10.1 3.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger ATP-synt_E PF05680.12 EEB09768.1 - 1 9.8 9.6 0.14 12.5 4.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain Rsa3 PF14615.6 EEB09769.1 - 1.2e-16 60.0 2.5 2.6e-16 58.9 0.6 2.0 1 1 1 2 2 2 1 Ribosome-assembly protein 3 Ribonuc_2-5A PF06479.12 EEB09769.1 - 0.023 14.9 0.5 0.029 14.6 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease 2-5A tRNA_m1G_MT PF01746.21 EEB09770.1 - 3.3e-40 137.9 0.6 4.8e-40 137.3 0.6 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase SOBP PF15279.6 EEB09770.1 - 0.81 10.2 4.2 1.4 9.4 4.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DNA_primase_S PF01896.19 EEB09771.1 - 2.7e-65 219.7 0.0 3.7e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Drc1-Sld2 PF11719.8 EEB09772.1 - 2.6e-35 122.8 32.0 1.1e-17 64.7 18.4 3.1 1 1 1 2 2 2 2 DNA replication and checkpoint protein Imm-NTF2 PF15655.6 EEB09772.1 - 0.0056 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 NTF2 fold immunity protein TPR_1 PF00515.28 EEB09773.1 - 1.8e-43 144.6 15.4 0.00017 21.3 0.0 10.6 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EEB09773.1 - 8.8e-40 131.6 21.3 1.8e-05 24.5 0.2 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 EEB09773.1 - 2.1e-22 79.5 10.7 0.00011 22.8 0.2 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EEB09773.1 - 5.2e-21 74.7 16.6 2.8e-06 27.5 0.1 8.1 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEB09773.1 - 2.3e-20 71.0 25.2 0.0013 18.8 0.0 11.3 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEB09773.1 - 4.2e-20 70.6 4.6 0.013 15.8 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEB09773.1 - 5.6e-20 70.8 11.4 4.1e-05 23.2 0.0 7.2 4 2 2 6 6 6 5 TPR repeat TPR_14 PF13428.6 EEB09773.1 - 3e-18 64.9 14.1 0.098 13.5 0.0 9.5 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEB09773.1 - 1.4e-17 63.9 20.3 0.00015 22.2 0.0 8.0 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEB09773.1 - 2.3e-14 52.2 14.3 0.31 11.2 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EEB09773.1 - 3.7e-09 36.2 12.4 0.069 13.0 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEB09773.1 - 1e-08 35.3 14.4 0.00059 20.0 0.1 5.7 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EEB09773.1 - 1.6e-07 31.0 3.7 8.5e-07 28.6 0.1 3.3 2 1 0 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 EEB09773.1 - 4.2e-07 30.0 1.2 0.1 12.8 0.0 5.7 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEB09773.1 - 6.8e-06 26.4 16.2 0.0019 18.7 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat Sel1 PF08238.12 EEB09773.1 - 0.00057 20.5 4.5 9.2 7.1 0.0 5.3 5 0 0 5 5 5 0 Sel1 repeat SHNi-TPR PF10516.9 EEB09773.1 - 0.0027 17.1 2.8 2.3 7.7 0.1 4.5 4 0 0 4 4 4 1 SHNi-TPR SieB PF14163.6 EEB09773.1 - 0.0097 15.4 1.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 Super-infection exclusion protein B TPR_4 PF07721.14 EEB09773.1 - 0.01 16.4 10.3 27 5.8 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 EEB09773.1 - 0.12 12.7 1.5 66 4.1 0.0 4.6 4 0 0 4 4 4 0 PPR repeat DUF4500 PF14937.6 EEB09773.1 - 0.14 12.2 0.8 0.46 10.5 0.0 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4500) DUF2151 PF10221.9 EEB09773.1 - 0.49 8.9 9.2 0.77 8.3 9.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Ndc1_Nup PF09531.10 EEB09773.1 - 0.69 8.5 3.0 0.88 8.2 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3824 PF12868.7 EEB09773.1 - 0.98 10.1 14.2 7.2 7.3 0.5 2.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Neur_chan_memb PF02932.16 EEB09773.1 - 1.6 8.8 4.8 4.1 7.4 4.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HemY_N PF07219.13 EEB09773.1 - 2.3 8.5 10.5 25 5.1 0.0 5.5 5 2 0 5 5 5 0 HemY protein N-terminus Ribosomal_S27e PF01667.17 EEB09774.1 - 1.3e-28 98.5 5.1 1.6e-28 98.2 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 PPI_Ypi1 PF07491.11 EEB09775.1 - 3.3e-23 81.3 10.6 8e-23 80.0 10.6 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor Vpu PF00558.19 EEB09775.1 - 0.015 15.1 0.4 0.02 14.7 0.4 1.2 1 0 0 1 1 1 0 Vpu protein WD40 PF00400.32 EEB09776.1 - 2e-50 167.7 29.8 8.3e-11 42.3 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEB09776.1 - 9e-10 38.7 2.5 0.057 13.7 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEB09776.1 - 0.00018 20.6 0.1 2.7 6.9 0.0 3.5 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEB09776.1 - 0.00054 18.7 5.4 0.036 12.7 0.1 4.1 2 2 3 5 5 5 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EEB09776.1 - 0.00085 17.9 0.0 0.6 8.6 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 EEB09776.1 - 0.0053 16.1 0.0 0.55 9.5 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 EEB09776.1 - 0.0067 16.3 0.0 19 5.3 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EEB09776.1 - 0.037 12.0 0.5 0.95 7.4 0.5 2.3 1 1 0 1 1 1 0 IKI3 family Cellulase PF00150.18 EEB09777.1 - 5.9e-14 52.2 1.8 8.7e-14 51.6 1.8 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4451 PF14616.6 EEB09778.2 - 1.5e-30 105.9 0.9 2.6e-30 105.1 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) eIF-5_eIF-2B PF01873.17 EEB09779.1 - 1.4e-41 141.1 0.2 2.9e-41 140.0 0.2 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EEB09779.1 - 0.0019 17.7 0.7 0.0044 16.5 0.2 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding Hid1 PF12722.7 EEB09779.1 - 0.015 13.4 12.8 0.019 13.1 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 EEB09779.1 - 0.14 10.6 12.2 0.17 10.4 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4695 PF15766.5 EEB09779.1 - 0.28 11.4 7.6 0.58 10.4 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Arc_trans_TRASH PF08394.10 EEB09779.1 - 0.62 10.4 7.1 1.3 9.4 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Ipi1_N PF12333.8 EEB09779.1 - 2.1 9.0 5.8 41 4.8 0.0 2.9 1 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation GREB1 PF15782.5 EEB09779.1 - 2.6 5.1 15.1 3.4 4.7 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GET2 PF08690.10 EEB09779.1 - 4.3 6.9 16.4 6.4 6.4 16.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SR-25 PF10500.9 EEB09779.1 - 6.9 6.2 27.5 13 5.3 27.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1708 PF08101.11 EEB09780.2 - 4.1e-37 128.4 0.3 2.3e-36 125.9 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) DUF4449 PF14613.6 EEB09781.2 - 4.4e-35 121.2 4.4 4.4e-35 121.2 4.4 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Homeodomain PF00046.29 EEB09782.2 - 1.1e-15 57.3 1.0 2.1e-15 56.3 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EEB09782.2 - 0.034 14.1 0.1 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 Homeobox KN domain Auxin_canalis PF05703.11 EEB09782.2 - 0.092 12.7 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Auxin canalisation Trp_syntA PF00290.20 EEB09783.1 - 9.8e-85 283.5 0.2 1.6e-84 282.8 0.2 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EEB09783.1 - 3.2e-49 168.0 0.4 5.1e-49 167.3 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTH2 PF01981.16 EEB09784.1 - 6.9e-45 152.1 0.1 6.9e-45 152.1 0.1 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 CBF PF03914.17 EEB09784.1 - 0.19 11.7 0.6 0.3 11.1 0.6 1.2 1 0 0 1 1 1 0 CBF/Mak21 family DUF3128 PF11326.8 EEB09784.1 - 0.22 11.9 4.8 0.13 12.7 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) U1snRNP70_N PF12220.8 EEB09785.1 - 7.6e-25 87.4 4.4 1.2e-24 86.7 4.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EEB09785.1 - 6e-17 61.2 0.0 9.6e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEB09785.1 - 0.00095 19.2 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif DUF4739 PF15893.5 EEB09785.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) PHM7_cyt PF14703.6 EEB09785.1 - 0.079 13.2 0.6 0.19 12.0 0.6 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DCP2 PF05026.13 EEB09786.1 - 3.6e-31 107.3 0.9 7e-31 106.4 0.9 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EEB09786.1 - 4e-14 52.8 0.0 6.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CobU PF02283.16 EEB09786.1 - 0.047 13.2 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Roc PF08477.13 EEB09787.2 - 0.0011 19.2 2.4 0.0014 18.8 0.6 2.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MTCP1 PF08991.10 EEB09787.2 - 0.0041 17.3 0.4 0.023 14.9 1.1 1.8 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type Adaptin_binding PF10199.9 EEB09787.2 - 0.0087 16.7 6.8 0.28 11.8 6.8 2.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 NRIP1_repr_1 PF15687.5 EEB09787.2 - 0.014 15.1 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 AAA_24 PF13479.6 EEB09787.2 - 0.026 14.2 0.2 0.12 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EEB09787.2 - 0.051 13.0 0.9 0.11 11.9 0.0 2.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EEB09787.2 - 0.059 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Y_phosphatase PF00102.27 EEB09787.2 - 0.062 12.8 1.8 0.099 12.2 1.8 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RING_5 PF14634.6 EEB09788.1 - 0.00065 19.6 5.7 0.001 19.0 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEB09788.1 - 0.0037 17.3 1.5 0.0091 16.0 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEB09788.1 - 0.0069 16.2 6.6 0.016 15.1 6.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEB09788.1 - 0.0082 16.4 3.9 0.013 15.8 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEB09788.1 - 0.043 13.7 5.4 0.082 12.8 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1677 PF07911.13 EEB09788.1 - 0.069 13.5 1.3 0.16 12.3 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Prok-RING_4 PF14447.6 EEB09788.1 - 0.13 12.1 5.2 3.2 7.7 5.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EEB09788.1 - 0.18 12.0 5.9 0.22 11.8 3.9 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 EEB09788.1 - 0.33 10.8 6.5 1.4 8.8 7.0 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EEB09788.1 - 1.5 8.7 6.4 5.9 6.8 6.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Yos1 PF08571.10 EEB09789.1 - 2e-27 95.3 0.4 2.3e-27 95.0 0.4 1.0 1 0 0 1 1 1 1 Yos1-like MIF4G PF02854.19 EEB09790.1 - 5.6e-46 156.9 19.5 3.2e-20 72.7 2.2 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EEB09790.1 - 6e-28 98.3 4.1 1.6e-27 96.9 4.1 1.7 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Oxidored_FMN PF00724.20 EEB09791.1 - 3.2e-61 207.5 0.0 4.1e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EEB09791.1 - 0.006 15.7 0.0 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) ICMT PF04140.14 EEB09792.1 - 2.5e-26 91.9 1.1 2.5e-26 91.9 1.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EEB09792.1 - 5.4e-13 49.3 1.0 5.4e-13 49.3 1.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EEB09792.1 - 2.3e-05 24.0 0.3 2.3e-05 24.0 0.3 1.6 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.12 EEB09792.1 - 0.00011 21.8 0.4 0.00017 21.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EEB09792.1 - 0.00056 18.8 0.4 0.00081 18.3 0.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PrgI PF12666.7 EEB09792.1 - 4.7 8.0 6.6 3.7 8.3 1.5 2.8 3 0 0 3 3 3 0 PrgI family protein APG17 PF04108.12 EEB09793.1 - 1.8e-55 188.7 17.8 2.6e-55 188.1 17.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 MazG PF03819.17 EEB09793.1 - 0.0025 18.0 0.1 0.011 15.9 0.1 2.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain EDR1 PF14381.6 EEB09793.1 - 0.1 12.3 1.9 10 5.8 0.6 2.8 1 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 VBS PF08913.10 EEB09793.1 - 0.15 12.5 7.0 8.1 6.9 0.1 4.1 3 2 1 4 4 4 0 Vinculin Binding Site OmpH PF03938.14 EEB09793.1 - 0.63 10.4 16.6 0.043 14.1 2.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2779 PF11074.8 EEB09793.1 - 2.4 8.6 7.1 5.2 7.5 0.6 3.4 2 2 1 3 3 3 0 Domain of unknown function(DUF2779) CENP-H PF05837.12 EEB09793.1 - 2.7 8.4 19.3 1.4 9.4 5.6 3.3 2 1 2 4 4 4 0 Centromere protein H (CENP-H) Hemerythrin PF01814.23 EEB09793.1 - 2.9 8.5 12.8 2.8 8.6 2.4 4.1 2 2 1 3 3 3 0 Hemerythrin HHE cation binding domain DUF3391 PF11871.8 EEB09793.1 - 3.5 8.2 6.2 0.82 10.2 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Filament PF00038.21 EEB09793.1 - 9.8 5.7 20.8 1.3e+02 2.0 17.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein RIO1 PF01163.22 EEB09794.1 - 6.9e-75 250.8 0.0 6.9e-75 250.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EEB09794.1 - 5.2e-05 23.3 0.1 0.02 14.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEB09794.1 - 0.00065 19.1 0.7 0.53 9.6 0.3 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EEB09794.1 - 0.0013 17.1 10.7 0.0021 16.4 10.7 1.5 1 0 0 1 1 1 1 CDC45-like protein SMC_N PF02463.19 EEB09795.1 - 1.1e-65 221.2 0.0 1.7e-65 220.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEB09795.1 - 9.7e-30 103.3 0.0 4.8e-29 101.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEB09795.1 - 4.1e-15 56.4 4.7 6.9e-08 32.6 0.0 3.4 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEB09795.1 - 1e-07 32.0 48.5 0.0008 19.2 20.7 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EEB09795.1 - 0.0025 18.4 43.7 0.0025 18.4 43.7 6.7 2 2 0 2 2 2 1 AAA domain zf-C4H2 PF10146.9 EEB09795.1 - 0.0088 16.4 6.4 0.0088 16.4 6.4 5.0 2 2 1 4 4 4 1 Zinc finger-containing protein ADIP PF11559.8 EEB09795.1 - 0.0091 16.1 12.9 0.0091 16.1 12.9 7.0 3 2 4 7 7 7 2 Afadin- and alpha -actinin-Binding AAA_29 PF13555.6 EEB09795.1 - 0.026 14.2 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EEB09795.1 - 2.8 8.0 0.0 2.8 8.0 0.0 5.6 4 2 1 5 5 5 0 Helicase HerA, central domain Methyltransf_9 PF08003.11 EEB09795.1 - 6.7 5.5 8.2 0.24 10.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TPR_MLP1_2 PF07926.12 EEB09796.1 - 0.012 15.6 1.5 0.012 15.6 1.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 EEB09796.1 - 0.014 15.0 2.1 0.017 14.7 2.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Med30 PF11315.8 EEB09796.1 - 0.024 14.9 0.5 0.034 14.4 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 Atg14 PF10186.9 EEB09796.1 - 0.032 13.3 0.3 0.034 13.2 0.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EEB09796.1 - 0.036 14.3 4.1 0.051 13.8 4.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-O PF09496.10 EEB09796.1 - 0.046 13.7 0.1 0.055 13.4 0.1 1.0 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component MICSWaP PF17018.5 EEB09796.1 - 0.059 12.9 0.1 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 Spore wall protein THOC7 PF05615.13 EEB09796.1 - 0.22 11.8 5.8 0.3 11.4 5.8 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF724 PF05266.14 EEB09796.1 - 0.29 11.0 2.9 0.39 10.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 EEB09796.1 - 0.3 11.5 4.7 0.45 11.0 4.7 1.3 1 0 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 EEB09796.1 - 0.31 11.1 3.4 0.41 10.7 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RRM_1 PF00076.22 EEB09797.1 - 1.2e-07 31.4 0.1 2.4e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEB09797.1 - 5e-05 23.1 0.1 9.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EEB09797.1 - 0.18 11.9 1.3 0.33 11.0 0.1 2.1 3 0 0 3 3 3 0 RNA binding motif UQ_con PF00179.26 EEB09798.2 - 9.3e-22 77.2 0.4 3.8e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEB09798.2 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain RCC1 PF00415.18 EEB09799.1 - 2.3e-27 95.3 18.9 4.7e-11 43.1 0.1 7.3 6 2 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEB09799.1 - 2.1e-22 78.4 21.0 6.2e-08 32.3 0.4 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat LVIVD PF08309.11 EEB09799.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 LVIVD repeat CTP_synth_N PF06418.14 EEB09800.2 - 8.2e-109 363.0 0.2 1.2e-108 362.5 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EEB09800.2 - 1.8e-57 194.2 0.0 3e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEB09800.2 - 0.00022 21.0 0.1 0.0036 17.1 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 S1 PF00575.23 EEB09801.2 - 3e-16 59.5 1.6 6.3e-16 58.5 1.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EEB09801.2 - 1.1e-08 35.0 0.2 2.4e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEB09801.2 - 1.7e-05 25.1 0.1 5.7e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEB09801.2 - 2.5e-05 24.7 0.2 6.3e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEB09801.2 - 7.8e-05 22.5 0.1 0.00021 21.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEB09801.2 - 0.0012 19.3 7.9 0.022 15.3 0.3 3.7 3 1 0 3 3 3 1 ABC transporter SRP54 PF00448.22 EEB09801.2 - 0.0079 15.8 0.3 0.018 14.7 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EEB09801.2 - 0.029 13.4 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PCB_OB PF17092.5 EEB09801.2 - 0.037 14.8 0.2 0.14 12.9 0.0 2.0 2 0 0 2 2 1 0 Penicillin-binding protein OB-like domain PhoH PF02562.16 EEB09801.2 - 0.039 13.4 0.4 0.16 11.4 0.4 2.0 1 1 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EEB09801.2 - 0.041 13.9 0.2 0.56 10.2 0.2 2.5 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EEB09801.2 - 0.043 13.8 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 EEB09801.2 - 0.1 12.3 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_GG_bind PF10258.9 EEB09801.2 - 0.13 12.4 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 1 0 PHAX RNA-binding domain AAA_33 PF13671.6 EEB09801.2 - 0.23 11.6 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EEB09801.2 - 0.38 11.1 0.0 0.38 11.1 0.0 2.7 4 0 0 4 4 3 0 AAA ATPase domain NIR_SIR PF01077.22 EEB09802.1 - 2.5e-50 170.1 0.0 5.2e-46 156.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EEB09802.1 - 4.1e-29 100.2 0.0 4.3e-13 48.9 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EEB09802.1 - 8.7e-27 94.1 0.0 2.3e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EEB09802.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HAD_2 PF13419.6 EEB09804.2 - 1e-23 84.4 0.0 1.5e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEB09804.2 - 1.2e-14 55.1 0.0 4.6e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEB09804.2 - 0.0007 19.7 0.0 0.22 11.7 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEB09804.2 - 0.02 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 EEB09804.2 - 0.034 14.5 0.0 0.076 13.4 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EEB09804.2 - 0.06 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Ras PF00071.22 EEB09805.2 - 4.9e-60 201.8 0.3 6.2e-60 201.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEB09805.2 - 4.5e-37 126.9 0.1 7.8e-37 126.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEB09805.2 - 1.3e-15 57.3 0.2 1.7e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEB09805.2 - 1.4e-06 27.9 0.1 2.2e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EEB09805.2 - 2.6e-06 27.1 0.1 1.7e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEB09805.2 - 2.7e-05 24.1 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EEB09805.2 - 3.1e-05 23.5 0.6 3.5e-05 23.3 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEB09805.2 - 3.1e-05 24.0 0.0 5.5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEB09805.2 - 0.00068 19.2 0.0 0.055 13.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEB09805.2 - 0.02 14.9 0.6 6.4 6.8 0.0 3.3 3 1 1 4 4 4 0 Dynamin family PduV-EutP PF10662.9 EEB09805.2 - 0.026 14.3 0.9 0.25 11.1 0.9 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EEB09805.2 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PQ-loop PF04193.14 EEB09806.1 - 3.1e-08 33.3 2.8 3.1e-08 33.3 2.8 3.7 4 1 0 4 4 4 2 PQ loop repeat DUF2370 PF10176.9 EEB09806.1 - 0.41 10.3 2.8 0.35 10.5 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) ThiF PF00899.21 EEB09807.1 - 2.1e-21 76.4 0.0 2.9e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family adh_short_C2 PF13561.6 EEB09808.2 - 1.4e-58 198.3 1.5 1.7e-58 198.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEB09808.2 - 5.1e-42 143.6 2.1 6.1e-42 143.3 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEB09808.2 - 2.5e-12 47.1 0.8 3.5e-12 46.6 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEB09808.2 - 2.4e-05 23.9 0.4 5.5e-05 22.7 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Spore_IV_A PF09547.10 EEB09808.2 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) GDP_Man_Dehyd PF16363.5 EEB09808.2 - 0.0067 15.9 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEB09808.2 - 0.0086 15.6 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family THF_DHG_CYH_C PF02882.19 EEB09808.2 - 0.012 14.9 0.0 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RLAN PF14401.6 EEB09808.2 - 0.013 15.2 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain HATPase_c PF02518.26 EEB09808.2 - 0.026 15.0 0.2 12 6.5 0.0 2.3 1 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OmpH PF03938.14 EEB09808.2 - 0.14 12.4 0.1 0.31 11.4 0.1 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HHH_8 PF14716.6 EQC52955.1 - 7.2e-11 42.3 0.1 2.1e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain Helicase_C PF00271.31 EQC52957.1 - 6.8e-17 61.8 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 EQC52957.1 - 0.051 13.7 0.4 9.4 6.4 0.2 2.2 1 1 1 2 2 2 0 Helicase C-terminal domain Inhibitor_I29 PF08246.12 EQC52957.1 - 0.14 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Chromo PF00385.24 EQC52958.1 - 2.9e-11 43.1 1.9 3.6e-11 42.8 1.9 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PBECR2 PF18810.1 EQC52958.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 RAP80_UIM PF18282.1 EQC52958.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif zf-CCHC PF00098.23 EQC52961.1 - 4.6e-07 29.6 3.2 9e-07 28.7 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EQC52961.1 - 0.14 11.9 2.5 0.24 11.2 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EQC52961.1 - 1.9 8.4 8.5 0.3 11.0 4.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 EQC52962.1 - 0.041 14.1 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein PSP PF04046.16 EQC52962.1 - 9.9 6.1 11.6 6.2 6.8 0.1 3.1 3 1 1 4 4 4 0 PSP Vma12 PF11712.8 EQC52963.1 - 7.7e-15 55.2 0.1 1.1e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase OSTMP1 PF09777.9 EQC52963.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Csc2 PF18320.1 EQC52964.1 - 0.22 10.4 0.3 0.27 10.2 0.3 1.1 1 0 0 1 1 1 0 Csc2 Crispr DUF4536 PF15055.6 EQC52968.1 - 1.7e-18 66.6 0.5 2.2e-18 66.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) LSM PF01423.22 EQC52970.1 - 7.9e-08 31.9 0.0 9.6e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain UPF0203 PF05254.12 EQC52971.1 - 7.1e-22 77.4 3.4 7.3e-22 77.4 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EQC52971.1 - 0.00029 21.1 2.2 0.0018 18.6 2.2 1.8 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EQC52971.1 - 0.00039 20.5 3.9 0.00058 19.9 0.6 2.0 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 EQC52971.1 - 0.0011 18.9 3.2 0.5 10.4 0.1 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EQC52971.1 - 0.0012 18.5 0.9 0.13 12.0 0.1 2.0 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF5339 PF17274.2 EQC52971.1 - 0.004 18.0 1.7 0.35 11.7 0.4 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5339) UCR_hinge PF02320.16 EQC52971.1 - 0.0073 16.5 4.7 0.13 12.4 4.5 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 EQC52971.1 - 0.041 13.9 1.4 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EQC52971.1 - 0.042 14.1 0.7 8.2 6.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-CCHC_3 PF13917.6 EQC52972.1 - 5.2e-17 61.5 5.9 1.1e-16 60.5 5.9 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2514 PF10721.9 EQC52972.1 - 0.13 12.2 1.1 0.19 11.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Zn_ribbon_2 PF12674.7 EQC52972.1 - 0.16 12.7 4.2 0.41 11.3 4.2 1.8 1 1 0 1 1 1 0 Putative zinc ribbon domain PPR_2 PF13041.6 EQC52973.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family Ribosomal_L31 PF01197.18 EQC52974.1 - 0.00024 21.3 0.0 0.00031 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 Gp_dh_C PF02800.20 EQC52976.1 - 6.7e-72 240.2 0.1 9.6e-72 239.7 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EQC52976.1 - 4.3e-40 136.1 0.1 1e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EQC52976.1 - 0.033 14.3 1.5 0.1 12.7 0.4 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EQC52976.1 - 0.039 13.9 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EQC52976.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3576 PF12100.8 EQC52976.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) Gp_dh_C PF02800.20 EQC52977.1 - 6.3e-72 240.3 0.1 9.6e-72 239.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EQC52977.1 - 6.6e-41 138.8 0.1 1.6e-40 137.5 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EQC52977.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DapB_N PF01113.20 EQC52977.1 - 0.045 13.9 2.1 0.13 12.4 0.7 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-UDP PF14569.6 EQC52978.1 - 0.11 12.7 10.8 0.2 11.8 10.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PolC_DP2 PF03833.13 EQC52978.1 - 0.44 8.3 8.6 0.44 8.4 8.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 COX7a PF02238.15 EQC52980.1 - 7.6e-16 58.3 0.4 8.8e-16 58.0 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII DUF4303 PF14136.6 EQC52980.1 - 0.063 13.0 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) VPS13 PF16908.5 EQC52983.1 - 1.6e-61 208.1 8.0 2e-55 188.2 0.4 4.6 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EQC52983.1 - 7.1e-38 130.3 10.2 3.8e-34 118.2 0.2 4.9 4 1 1 5 5 5 3 Repeating coiled region of VPS13 Chorein_N PF12624.7 EQC52983.1 - 2.6e-32 111.4 0.0 1.3e-31 109.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EQC52983.1 - 6.9e-25 87.9 1.3 1.4e-21 77.1 1.3 3.1 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DUF799 PF05643.11 EQC52983.1 - 0.064 12.8 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) NUFIP1 PF10453.9 EQC52984.1 - 3.9e-13 49.0 6.8 3.9e-13 49.0 6.8 2.4 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Torus PF16131.5 EQC52984.1 - 0.00023 21.8 0.3 0.00023 21.8 0.3 2.3 2 1 1 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 EQC52984.1 - 0.0027 17.7 8.5 0.0042 17.1 8.5 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EQC52984.1 - 0.0039 17.1 3.1 0.0066 16.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EQC52984.1 - 0.026 15.0 6.8 0.048 14.1 6.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CIAPIN1 PF05093.13 EQC52984.1 - 0.15 12.6 0.3 0.15 12.6 0.3 2.6 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CCCH_4 PF18044.1 EQC52984.1 - 0.22 11.3 4.7 0.4 10.6 4.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Tristanin_u2 PF16638.5 EQC52984.1 - 7.2 7.5 13.3 3.4 8.5 2.7 2.8 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Methyltransf_23 PF13489.6 EQC52986.1 - 4.3e-23 82.0 0.0 1e-22 80.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EQC52986.1 - 2.2e-06 27.2 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EQC52986.1 - 0.00017 22.2 0.0 0.00027 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQC52986.1 - 0.00019 22.0 0.0 0.0003 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EQC52986.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DCP1 PF06058.13 EQC52987.1 - 3e-21 75.5 0.3 3.5e-21 75.3 0.3 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family DUF1242 PF06842.12 EQC52991.1 - 4.7e-19 67.9 1.9 7.3e-19 67.3 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF2373 PF10180.9 EQC52992.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF2688 PF10892.8 EQC52992.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) DAD PF02109.16 EQC52993.1 - 0.07 13.5 3.8 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 DAD family Caveolin PF01146.17 EQC52993.1 - 4 7.4 7.1 0.66 9.9 0.2 2.1 2 0 0 2 2 2 0 Caveolin Pribosyltran PF00156.27 EQC52996.1 - 3.7e-08 33.1 0.0 7.4e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.19 EQC52996.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase B12-binding PF02310.19 EQC52996.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain ALS_ss_C PF10369.9 EQC52997.1 - 9.2e-17 61.0 0.0 1.4e-15 57.3 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 EQC52997.1 - 3.1e-11 42.9 0.2 6.8e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EQC52997.1 - 3e-09 36.6 0.1 5.6e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain YejG PF13989.6 EQC52997.1 - 0.051 14.0 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein Barstar PF01337.18 EQC52997.1 - 0.058 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Peptidase_M24 PF00557.24 EQC52998.1 - 1.8e-44 151.9 0.0 2.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3391 PF11871.8 EQC52998.1 - 0.15 12.6 4.7 0.37 11.3 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1910 PF08928.10 EQC52999.1 - 0.042 13.8 0.2 0.042 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) PHA-1 PF06542.11 EQC52999.1 - 0.19 10.5 3.4 0.21 10.4 3.4 1.0 1 0 0 1 1 1 0 Regulator protein PHA-1 Helicase_C PF00271.31 EQC53000.1 - 5e-17 62.2 0.0 7.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 EQC53000.1 - 0.026 14.7 0.4 6 7.0 0.2 2.1 1 1 1 2 2 2 0 Helicase C-terminal domain Inhibitor_I29 PF08246.12 EQC53000.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Orbi_VP4 PF05059.12 EQC53000.1 - 0.16 9.9 0.0 0.68 7.9 0.1 1.9 2 1 0 2 2 2 0 Orbivirus VP4 core protein AA_permease_2 PF13520.6 EQC53001.1 - 2.7e-58 197.8 53.1 3.3e-58 197.5 53.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EQC53001.1 - 1.5e-10 40.3 44.9 2e-10 39.9 44.9 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0242 PF06785.11 EQC53001.1 - 0.85 9.7 6.1 0.33 11.1 0.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Zn_clus PF00172.18 EQC53002.1 - 9.9e-07 28.8 14.2 2.4e-06 27.5 14.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MA3 PF02847.17 EQC53004.1 - 2e-29 101.9 0.7 5.1e-29 100.5 0.5 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EQC53004.1 - 3.2e-13 49.8 0.1 6.2e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain Peptidase_C48 PF02902.19 EQC53007.1 - 1.5e-43 149.1 0.0 3.6e-43 147.9 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MRP_L53 PF10780.9 EQC53008.1 - 3e-16 59.3 0.0 4.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF5079 PF16882.5 EQC53009.1 - 0.00047 20.1 0.6 0.00051 20.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5079) DUF716 PF04819.12 EQC53009.1 - 0.0096 15.6 1.7 0.011 15.3 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF716) PIG-P PF08510.12 EQC53009.1 - 0.029 14.3 2.9 0.031 14.2 2.9 1.1 1 0 0 1 1 1 0 PIG-P DUF1772 PF08592.11 EQC53009.1 - 0.049 13.9 0.1 0.051 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Complex1_LYR PF05347.15 EQC53010.1 - 0.1 12.7 3.7 0.23 11.5 3.7 1.7 1 1 0 1 1 1 0 Complex 1 protein (LYR family) rRNA_proc-arch PF13234.6 EQC53011.1 - 1.8e-73 247.8 0.3 4.9e-73 246.4 0.3 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EQC53011.1 - 1.1e-58 197.6 0.3 3.3e-58 196.0 0.1 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EQC53011.1 - 6.8e-19 68.3 0.1 6e-18 65.2 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EQC53011.1 - 1.1e-06 28.9 0.0 5.2e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 EQC53011.1 - 0.0074 15.4 0.1 0.021 13.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EQC53011.1 - 0.029 14.7 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain UbiA PF01040.18 EQC53016.1 - 6.7e-42 143.5 11.2 8.7e-42 143.2 11.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Daxx PF03344.15 EQC53022.1 - 0.038 14.1 0.1 0.082 13.0 0.1 1.5 1 1 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain tRNA-synt_1g PF09334.11 EQC53023.1 - 9e-72 242.0 2.9 2.3e-42 145.1 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EQC53023.1 - 1.5e-17 63.1 0.0 3.8e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EQC53023.1 - 2.1e-06 27.3 0.6 7.7e-05 22.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EQC53023.1 - 0.0091 15.0 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) Chromo PF00385.24 EQC53024.1 - 1.2e-13 50.7 2.5 1.4e-13 50.5 2.5 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Importin_rep_2 PF18786.1 EQC53024.1 - 0.19 11.6 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 Importin 13 repeat Pga1 PF10333.9 EQC53025.1 - 3.8e-05 23.6 2.2 0.0011 18.8 2.2 2.1 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator B12D PF06522.11 EQC53027.1 - 0.027 14.3 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PIG-Y PF15159.6 EQC53028.1 - 6.9e-14 52.5 8.4 8.7e-14 52.2 8.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF3810 PF12725.7 EQC53028.1 - 0.53 9.6 2.8 0.62 9.4 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) S36_mt PF10937.8 EQC53029.1 - 6.6e-08 34.1 1.4 7e-06 27.6 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial DUF3552 PF12072.8 EQC53030.1 - 0.067 12.6 1.8 0.079 12.4 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Pro_CA PF00484.19 EQC53032.1 - 1.2e-48 165.4 0.1 1.8e-48 164.8 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF3018 PF11455.8 EQC53032.1 - 0.068 13.1 0.3 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Ribosomal_L4 PF00573.22 EQC53033.1 - 4.5e-40 137.4 2.5 7e-40 136.8 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EQC53033.1 - 1.8e-26 92.0 4.5 1.8e-26 92.0 4.5 2.3 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Rpp20 PF12328.8 EQC53034.1 - 5.5e-10 39.3 0.5 2.5e-09 37.2 0.5 1.7 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Bac_DnaA PF00308.18 EQC53034.1 - 0.085 12.7 0.1 0.099 12.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial dnaA protein Nucleo_LEF-12 PF06256.11 EQC53034.1 - 0.2 11.4 1.0 0.74 9.5 0.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein APG12 PF04110.13 EQC53036.1 - 3.6e-30 104.2 0.1 5e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EQC53036.1 - 0.00051 20.2 0.0 0.00065 19.9 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like PUF PF00806.19 EQC53037.1 - 9.8e-19 65.9 0.0 0.0013 18.3 0.0 5.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EQC53037.1 - 2.5e-11 43.2 0.0 5.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EQC53037.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EQC53037.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif TGT PF01702.18 EQC53038.1 - 1e-49 169.6 0.0 9.5e-49 166.4 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Phosducin PF02114.16 EQC53038.1 - 4.2e-10 39.0 0.3 7e-10 38.3 0.3 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EQC53038.1 - 1.8e-06 27.9 0.1 4.3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin ZapB PF06005.12 EQC53039.1 - 0.0015 18.9 1.3 0.0015 18.9 1.3 3.1 2 2 1 3 3 3 1 Cell division protein ZapB FlaC_arch PF05377.11 EQC53039.1 - 0.0042 17.4 5.0 0.0043 17.4 0.8 2.9 2 2 1 3 3 3 1 Flagella accessory protein C (FlaC) Apolipoprotein PF01442.18 EQC53039.1 - 0.018 14.9 11.2 0.035 14.0 11.2 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BAR_2 PF10455.9 EQC53039.1 - 0.02 14.1 5.2 0.019 14.1 4.3 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DivIC PF04977.15 EQC53039.1 - 0.021 14.6 1.1 0.021 14.6 1.1 2.9 1 1 2 3 3 3 0 Septum formation initiator Hs1pro-1_C PF07014.12 EQC53039.1 - 0.032 13.7 1.0 0.04 13.4 1.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus KfrA_N PF11740.8 EQC53039.1 - 0.052 14.2 2.2 0.21 12.3 0.4 2.2 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term bZIP_1 PF00170.21 EQC53039.1 - 0.068 13.3 1.4 0.068 13.3 1.4 3.4 2 1 1 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 EQC53039.1 - 0.074 12.9 0.8 0.074 12.9 0.8 3.1 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 EQC53039.1 - 0.22 10.4 13.3 0.11 11.3 9.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_S PF02609.16 EQC53039.1 - 0.5 10.5 5.8 0.67 10.1 0.4 3.6 3 2 0 3 3 2 0 Exonuclease VII small subunit Exonuc_VII_L PF02601.15 EQC53039.1 - 0.57 9.7 7.9 0.79 9.2 7.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EQC53039.1 - 0.72 9.1 4.5 1.3 8.3 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 EQC53039.1 - 0.75 10.1 10.5 0.25 11.7 5.5 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 EQC53039.1 - 0.77 10.1 8.4 0.72 10.2 0.7 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 EQC53039.1 - 0.8 9.8 6.8 0.26 11.4 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EQC53039.1 - 1.8 9.0 11.6 0.51 10.7 5.6 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nsp1_C PF05064.13 EQC53039.1 - 1.8 8.4 11.7 7.2 6.5 0.1 3.2 1 1 2 3 3 3 0 Nsp1-like C-terminal region BRE1 PF08647.11 EQC53039.1 - 1.9 8.6 12.2 1.9 8.6 0.2 3.1 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 EQC53039.1 - 2.2 9.0 11.0 1.2e+02 3.3 11.0 2.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF3287 PF11690.8 EQC53039.1 - 2.4 7.9 6.9 7.8 6.2 1.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2203 PF09969.9 EQC53039.1 - 5 7.9 7.3 1.8 9.3 1.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SlyX PF04102.12 EQC53039.1 - 5.5 7.7 9.3 19 6.0 0.3 3.1 1 1 1 3 3 3 0 SlyX DASH_Hsk3 PF08227.11 EQC53039.1 - 8 6.9 10.4 12 6.4 0.1 3.8 3 1 1 4 4 4 0 DASH complex subunit Hsk3 like MMU163 PF17119.5 EQC53042.1 - 1.4e-10 40.8 0.1 9.7e-08 31.5 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis ArsD PF06953.11 EQC53042.1 - 0.0088 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Arsenical resistance operon trans-acting repressor ArsD DUF2358 PF10184.9 EQC53042.1 - 0.028 14.7 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) PSCyt3 PF07627.11 EQC53042.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Ribosomal_L30 PF00327.20 EQC53043.1 - 5.4e-10 39.0 0.1 7.6e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Retrotrans_gag PF03732.17 EQC53044.1 - 8.1e-08 32.4 0.1 1.8e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein Zn_clus PF00172.18 EQC53045.1 - 1.2e-06 28.5 13.2 2.6e-06 27.4 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0242 PF06785.11 EQC53049.1 - 0.013 15.6 28.6 0.11 12.6 14.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EQC53049.1 - 0.12 11.2 30.3 0.18 10.7 15.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EQC53049.1 - 0.19 12.2 36.0 3.1 8.3 4.6 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 EQC53049.1 - 0.8 9.1 29.6 2.6 7.4 16.5 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 ERM PF00769.19 EQC53049.1 - 0.86 9.4 28.9 0.22 11.3 17.2 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 EQC53049.1 - 0.97 9.6 31.3 0.055 13.7 15.7 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SAP18 PF06487.12 EQC53050.1 - 1.3e-17 64.3 0.0 2.2e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TPR_3 PF07720.12 EQC53051.1 - 0.24 11.4 0.3 0.24 11.4 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 EQC53052.1 - 1.6e-20 73.9 0.0 3.8e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cyclin PF08613.11 EQC53053.1 - 7.6e-34 117.4 0.5 9.8e-34 117.1 0.5 1.2 1 0 0 1 1 1 1 Cyclin Telomerase_RBD PF12009.8 EQC53054.1 - 2.1e-42 144.4 3.7 2.1e-42 144.4 3.7 2.5 2 1 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EQC53054.1 - 8.7e-11 41.8 0.6 4e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) B12D PF06522.11 EQC53055.1 - 0.00011 21.9 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Adeno_PX PF05829.12 EQC53055.1 - 0.0051 16.7 1.0 0.0065 16.3 1.0 1.2 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) RNase_H PF00075.24 EQC53057.1 - 1.1e-38 132.7 0.0 2e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EQC53057.1 - 2.1e-20 72.7 4.0 4.6e-20 71.6 4.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3767 PF12597.8 EQC53060.1 - 1.8e-19 69.4 0.2 2.2e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF5506 PF17611.2 EQC53060.1 - 0.055 13.4 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5506) RNB PF00773.19 EQC53061.1 - 5.5e-51 173.8 0.1 1.9e-50 172.1 0.1 1.8 1 1 0 1 1 1 1 RNB domain Inhibitor_I78 PF11720.8 EQC53063.1 - 7.2e-07 29.2 0.0 8.1e-07 29.0 0.0 1.2 1 1 0 1 1 1 1 Peptidase inhibitor I78 family MmoB_DmpM PF02406.17 EQC53063.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 MmoB/DmpM family potato_inhibit PF00280.18 EQC53063.1 - 0.16 12.6 0.2 0.22 12.2 0.2 1.3 1 0 0 1 1 1 0 Potato inhibitor I family MAGUK_N_PEST PF10608.9 EQC53064.1 - 0.095 13.1 1.2 0.12 12.8 1.2 1.1 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK APG17 PF04108.12 EQC53065.1 - 0.0036 16.5 0.5 0.0044 16.2 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF327 PF03885.13 EQC53065.1 - 0.1 12.5 1.5 1.6 8.7 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF327) Rgp1 PF08737.10 EQC53066.1 - 4.5e-37 128.2 0.0 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Rgp1 SOG2 PF10428.9 EQC53066.1 - 6.2 5.9 24.0 5.5 6.1 12.6 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Hpt PF01627.23 EQC53068.1 - 1e-11 44.9 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Hpt domain AP_endonuc_2 PF01261.24 EQC53068.1 - 0.011 15.2 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel CDC13_N PF16853.5 EQC53068.1 - 0.043 13.3 0.3 0.059 12.9 0.3 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus UPF0139 PF03669.13 EQC53070.1 - 2.9e-05 23.9 3.6 3.4e-05 23.6 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF2339 PF10101.9 EQC53070.1 - 0.025 13.2 2.8 0.027 13.1 2.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Hexapep PF00132.24 EQC53071.1 - 5.4e-14 51.3 9.5 4.1e-11 42.1 4.9 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EQC53071.1 - 1.6e-11 43.8 12.2 6.2e-10 38.7 3.9 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EQC53071.1 - 5.9e-11 42.4 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Cmc1 PF08583.10 EQC53074.1 - 1.4e-15 57.0 4.5 1.7e-15 56.8 4.4 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EQC53074.1 - 0.00024 20.8 2.1 0.00035 20.2 2.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 EQC53074.1 - 0.0013 19.1 3.1 0.74 10.2 0.1 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EQC53074.1 - 0.096 12.9 2.4 0.16 12.1 2.4 1.4 1 0 0 1 1 1 0 CHCH domain Mre11_DNA_bind PF04152.14 EQC53075.1 - 1.2e-52 178.6 0.2 1.2e-52 178.6 0.2 2.5 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EQC53075.1 - 5.7e-14 53.1 2.2 6.3e-14 53.0 1.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EQC53075.1 - 3.7e-06 27.2 0.0 6.9e-05 23.1 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sporozoite_P67 PF05642.11 EQC53075.1 - 0.0056 14.8 3.2 0.0078 14.4 3.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Ku_N PF03731.15 EQC53076.1 - 6.3e-44 150.3 0.0 9.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 EQC53076.1 - 2e-32 112.6 0.0 3.3e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EQC53076.1 - 9.3e-16 58.3 0.0 2.2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EQC53076.1 - 1.4e-08 34.3 0.0 2.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EQC53076.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain zf-met PF12874.7 EQC53077.1 - 0.00044 20.5 8.2 0.0027 18.1 1.2 3.5 3 1 0 3 3 3 1 Zinc-finger of C2H2 type OrsD PF12013.8 EQC53077.1 - 0.0011 19.3 9.1 0.021 15.3 1.5 3.0 2 2 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 EQC53077.1 - 0.0066 16.7 16.2 0.014 15.7 2.6 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding P53_tetramer PF07710.11 EQC53077.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 P53 tetramerisation motif zf-3CxxC_2 PF17180.4 EQC53077.1 - 0.24 12.2 8.1 14 6.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-binding domain DUF629 PF04780.12 EQC53077.1 - 0.94 7.9 11.0 0.23 10.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 EQC53077.1 - 1.3 10.1 25.6 0.35 11.8 3.9 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizosaccharomyces_japonicus_yFS275-SJ5/GCA_000149845.2_SJ5_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizosaccharomyces_japonicus_yFS275-SJ5/GCA_000149845.2_SJ5_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizosaccharomyces_japonicus_yFS275-SJ5/GCA_000149845.2_SJ5_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Schizosaccharomyces_japonicus_yFS275-SJ5/GCA_000149845.2_SJ5_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 05:01:06 2019 # [ok]