# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Retrotrans_gag PF03732.12 EEB04996.2 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 EEB04997.1 - 5.1e-07 29.6 0.2 8e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Helicase_C PF00271.26 EEB05000.2 - 1.6e-13 50.2 0.0 3.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB05000.2 - 3.7e-10 39.5 0.0 9.1e-09 35.0 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEB05000.2 - 1.1e-09 38.4 18.4 1.2e-07 31.8 0.9 4.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3505) TetR_N PF00440.18 EEB05000.2 - 4.1e-05 23.1 1.0 0.35 10.5 0.1 3.5 3 0 0 3 3 3 2 Bacterial regulatory proteins, tetR family ResIII PF04851.10 EEB05000.2 - 0.0039 17.0 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEB05003.2 - 1.4e-13 50.4 0.0 5.2e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EEB05003.2 - 0.0042 17.0 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain zf-met PF12874.2 EEB05004.1 - 0.0094 16.1 2.3 0.033 14.3 1.6 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3505 PF12013.3 EEB05004.1 - 0.039 14.1 0.1 0.039 14.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) C1_3 PF07649.7 EEB05004.1 - 0.27 11.3 5.5 27 4.9 0.0 3.7 3 0 0 3 3 3 0 C1-like domain zf-Di19 PF05605.7 EEB05004.1 - 0.73 10.0 16.1 0.22 11.6 0.3 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EEB05004.1 - 1.5 8.8 8.4 0.061 13.2 1.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Asp_protease_2 PF13650.1 EEB05005.1 - 3.3e-09 37.1 0.0 5.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EEB05005.1 - 2.7e-07 30.2 0.0 6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EEB05005.1 - 7.8e-06 25.7 0.0 7.7e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 EEB05005.1 - 1.5e-05 24.7 1.8 3e-05 23.7 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EEB05005.1 - 0.031 13.7 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF903 PF06004.7 EEB05005.1 - 0.066 12.7 0.1 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) zf-CCHC_4 PF14392.1 EEB05005.1 - 0.071 12.7 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 EEB05005.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.12 EEB05010.2 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein HMG_box PF00505.14 EEB05014.2 - 7.9e-19 67.6 1.4 9.2e-19 67.4 0.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEB05014.2 - 7.9e-07 29.3 0.2 1.8e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 HMG-box domain HisG_C PF08029.6 EEB05014.2 - 0.12 12.2 0.0 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain Homeobox_KN PF05920.6 EEB05015.2 - 0.14 11.9 0.4 0.27 10.9 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain Chromo PF00385.19 EEB05017.1 - 0.00018 21.1 2.4 0.00029 20.4 1.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EEB05019.2 - 7.7e-12 45.0 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEB05019.2 - 1.7e-10 41.1 0.8 6.2e-10 39.2 0.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Helicase_C PF00271.26 EEB05019.2 - 1e-07 31.7 0.0 5.2e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB05019.2 - 0.00023 21.0 0.0 0.0017 18.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EEB05019.2 - 0.0031 16.8 0.0 0.0081 15.4 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain Pkinase PF00069.20 EEB05020.1 - 1.9e-49 168.1 0.0 2.1e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05020.1 - 3.7e-32 111.4 0.0 4.3e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05020.1 - 1.9e-06 27.0 0.0 2.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB05020.1 - 0.00017 20.7 0.0 0.00046 19.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2240 PF09999.4 EEB05021.2 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) zf-met PF12874.2 EEB05022.1 - 0.00085 19.4 0.3 0.00085 19.4 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEB05022.1 - 0.0013 18.7 0.1 0.0046 17.0 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEB05022.1 - 0.013 15.7 0.1 0.013 15.7 0.1 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger DUF3505 PF12013.3 EEB05022.1 - 0.046 13.9 1.2 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-C2H2 PF00096.21 EEB05022.1 - 0.065 13.6 0.3 0.065 13.6 0.2 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EEB05022.1 - 0.08 13.0 4.2 0.91 9.6 0.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3505 PF12013.3 EEB05023.1 - 1.8e-05 24.8 6.6 0.01 16.0 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3505) zf-C2H2_6 PF13912.1 EEB05023.1 - 0.0085 15.9 2.2 0.0085 15.9 1.5 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger P53_tetramer PF07710.6 EEB05023.1 - 0.049 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif zf-C2H2_jaz PF12171.3 EEB05023.1 - 0.063 13.4 7.8 0.61 10.3 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB05023.1 - 0.85 9.9 7.3 1 9.6 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3505 PF12013.3 EEB05024.1 - 6e-05 23.2 4.0 0.0079 16.4 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3505) zf-C2H2 PF00096.21 EEB05024.1 - 0.088 13.1 0.4 0.088 13.1 0.2 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEB05024.1 - 0.26 11.4 0.3 0.26 11.4 0.2 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEB05024.1 - 0.61 10.5 0.1 0.61 10.5 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger AA_permease_2 PF13520.1 EEB05026.1 - 6.5e-52 176.4 53.3 8.2e-52 176.1 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB05026.1 - 8e-14 50.8 45.8 1.1e-13 50.4 31.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1211 PF06736.6 EEB05026.1 - 0.014 15.5 9.5 0.027 14.6 1.9 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) RTA1 PF04479.8 EEB05028.1 - 2.1e-18 66.6 0.5 2.1e-18 66.6 0.3 1.3 2 0 0 2 2 2 1 RTA1 like protein AA_permease_2 PF13520.1 EEB05029.1 - 2.8e-53 180.9 51.9 3.5e-53 180.6 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB05029.1 - 7.1e-19 67.4 43.8 1.2e-18 66.7 30.4 1.3 1 1 0 1 1 1 1 Amino acid permease Transferase PF02458.10 EEB05030.1 - 6.6e-26 90.7 0.0 1.1e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family Transferase PF02458.10 EEB05031.1 - 2.4e-25 88.8 0.0 6.6e-24 84.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family Gp_dh_C PF02800.15 EEB05035.1 - 1.2e-74 248.9 0.1 1.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEB05035.1 - 1.3e-61 207.0 0.1 2.6e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EEB05035.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EEB05035.1 - 0.024 14.5 1.8 0.079 12.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EEB05035.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RhoGAP PF00620.22 EEB05036.1 - 2.1e-17 63.1 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Arm PF00514.18 EEB05037.1 - 1.7e-71 233.8 30.0 4e-10 39.1 0.0 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEB05037.1 - 1.6e-22 79.5 14.3 3.1e-05 24.1 0.2 7.8 2 2 4 7 7 7 7 HEAT repeats HEAT PF02985.17 EEB05037.1 - 2.5e-14 51.9 17.8 0.033 14.2 0.2 9.5 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EEB05037.1 - 5.5e-12 45.7 16.9 0.0044 17.4 0.2 8.4 6 3 4 10 10 10 4 HEAT-like repeat KAP PF05804.7 EEB05037.1 - 1e-11 43.5 1.0 1.5e-11 42.9 0.7 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EEB05037.1 - 1.9e-10 40.2 11.5 0.00085 18.5 0.1 3.6 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EEB05037.1 - 1.1e-09 37.8 6.1 5e-06 25.8 1.3 4.2 1 1 2 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.15 EEB05037.1 - 3e-08 32.4 16.8 1.1e-05 24.0 0.5 2.8 1 1 2 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 EEB05037.1 - 0.00075 17.8 8.7 0.0084 14.4 3.3 2.7 1 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EEB05037.1 - 0.051 14.0 6.3 38 5.1 0.0 6.5 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat SH3_1 PF00018.23 EEB05038.2 - 1.3e-05 24.4 1.2 1.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEB05038.2 - 4.1e-05 23.0 0.0 9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Dynamin_N PF00350.18 EEB05039.1 - 1.9e-15 57.0 1.0 8.6e-15 54.9 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EEB05039.1 - 9.6e-10 38.4 0.0 5.2e-09 36.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEB05039.1 - 1.3e-09 37.7 0.7 6.5e-09 35.4 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EEB05039.1 - 0.00058 19.3 0.1 0.96 8.9 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.8 EEB05039.1 - 0.0013 17.6 0.2 0.0061 15.4 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) cobW PF02492.14 EEB05039.1 - 0.0017 17.8 0.1 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EEB05039.1 - 0.0042 17.5 0.0 1.1 9.7 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EEB05039.1 - 0.0097 15.1 0.4 2.3 7.4 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF489 PF04356.7 EEB05039.1 - 0.028 14.0 0.8 0.059 12.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF489) AAA_16 PF13191.1 EEB05039.1 - 0.03 14.3 2.2 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EEB05039.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEB05039.1 - 0.11 12.8 2.0 0.52 10.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain DUF1043 PF06295.7 EEB05039.1 - 0.12 12.0 4.0 8.6 6.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Arrestin_C PF02752.17 EEB05040.1 - 3.2e-14 53.2 0.1 6.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEB05040.1 - 4e-05 23.4 0.2 0.00012 21.9 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Cullin_binding PF03556.10 EEB05041.1 - 4.9e-30 104.0 2.7 8.6e-30 103.2 0.2 2.1 2 1 1 3 3 3 1 Cullin binding RGS PF00615.14 EEB05041.1 - 0.34 11.0 3.5 0.19 11.8 0.7 2.0 2 1 0 2 2 2 0 Regulator of G protein signaling domain Ribosomal_L2_C PF03947.13 EEB05042.1 - 3.4e-38 130.3 2.7 3.4e-38 130.3 1.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEB05042.1 - 8.5e-14 51.2 0.1 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Allantoicase PF03561.10 EEB05043.1 - 3.3e-105 348.0 0.0 3.1e-55 185.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Asp_Glu_race PF01177.17 EEB05044.2 - 7.2e-29 101.2 0.1 8.5e-29 100.9 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fungal_trans PF04082.13 EEB05045.2 - 1e-20 73.6 0.1 1.9e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB05045.2 - 5.8e-05 22.9 10.9 0.00011 22.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EEB05046.1 - 1.5e-77 260.2 0.0 1.7e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EEB05046.1 - 0.021 14.7 4.6 11 6.1 0.0 4.2 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family FtsK_SpoIIIE PF01580.13 EEB05046.1 - 0.024 14.0 0.0 0.058 12.8 0.0 1.5 1 1 1 2 2 2 0 FtsK/SpoIIIE family 6PF2K PF01591.13 EEB05047.1 - 2.8e-46 157.3 4.0 3.9e-46 156.8 2.8 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.5 EEB05047.1 - 1.6e-07 30.8 0.3 2.7e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEB05047.1 - 2.8e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEB05047.1 - 1.6e-05 25.7 0.0 5.9e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain His_Phos_1 PF00300.17 EEB05047.1 - 0.047 13.7 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Zeta_toxin PF06414.7 EEB05047.1 - 0.051 12.6 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 EEB05047.1 - 0.052 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF59 PF01883.14 EEB05048.1 - 2.5e-09 36.9 0.0 4.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 Vps51 PF08700.6 EEB05049.1 - 1.5e-11 43.9 0.1 9.2e-11 41.4 0.1 2.4 1 0 0 1 1 1 1 Vps51/Vps67 V-SNARE PF05008.10 EEB05049.1 - 0.13 12.4 0.1 0.13 12.4 0.0 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Kinesin PF00225.18 EEB05050.1 - 2.1e-09 36.5 0.0 2.2e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain T2SE PF00437.15 EEB05050.1 - 0.052 12.4 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EEB05050.1 - 0.72 9.7 2.9 7 6.5 0.7 3.2 2 1 0 2 2 2 0 AAA domain Orn_Arg_deC_N PF02784.11 EEB05051.1 - 5e-75 251.9 0.0 8.8e-75 251.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EEB05051.1 - 2e-35 121.0 0.1 4.1e-35 120.0 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Adenylsucc_synt PF00709.16 EEB05052.1 - 3.1e-168 559.8 0.0 3.5e-168 559.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase zf-H2C2_2 PF13465.1 EEB05053.1 - 7.8e-10 38.5 5.3 1.4e-06 28.3 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEB05053.1 - 9.5e-06 25.6 0.2 9.5e-06 25.6 0.1 3.9 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05053.1 - 6.8e-05 22.9 7.5 0.00012 22.1 0.1 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger DUF1319 PF07028.6 EEB05053.1 - 0.038 14.1 1.0 0.057 13.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) zf-met PF12874.2 EEB05053.1 - 0.093 12.9 0.1 5.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEB05053.1 - 0.11 12.6 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EEB05053.1 - 0.3 11.2 3.9 16 5.6 0.5 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EEB05053.1 - 0.38 10.7 2.9 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DivIC PF04977.10 EEB05053.1 - 1.6 8.2 4.3 0.4 10.1 0.8 1.6 2 0 0 2 2 2 0 Septum formation initiator Sec2p PF06428.6 EEB05053.1 - 4.2 7.2 7.3 18 5.2 0.7 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PemK PF02452.12 EEB05054.1 - 0.076 13.2 0.1 0.094 12.9 0.1 1.1 1 0 0 1 1 1 0 PemK-like protein Microcephalin PF12258.3 EEB05055.1 - 0.059 12.3 1.5 0.066 12.1 1.0 1.2 1 0 0 1 1 1 0 Microcephalin protein DUF2201_N PF13203.1 EEB05055.1 - 0.14 11.3 1.1 0.15 11.2 0.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Porin_3 PF01459.17 EEB05056.1 - 2.6e-58 197.4 0.5 3e-58 197.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2408 PF10303.4 EEB05057.1 - 7.8e-59 197.6 4.4 3.2e-33 114.6 0.1 4.9 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) RVT_3 PF13456.1 EEB05057.1 - 0.015 15.1 1.2 0.94 9.3 0.0 3.3 3 0 0 3 3 3 0 Reverse transcriptase-like FlgN PF05130.7 EEB05057.1 - 0.35 11.1 4.2 3.7 7.7 0.1 3.5 3 2 1 4 4 4 0 FlgN protein DUF904 PF06005.7 EEB05057.1 - 1.3 9.3 8.8 0.26 11.6 0.9 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF904) PQ-loop PF04193.9 EEB05059.1 - 9.7e-34 114.7 17.1 4.2e-20 71.0 1.4 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EEB05059.1 - 0.057 13.3 0.6 0.057 13.3 0.4 2.7 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange UBX PF00789.15 EEB05060.1 - 0.00071 19.5 0.1 0.0037 17.2 0.0 2.2 3 0 0 3 3 3 1 UBX domain UN_NPL4 PF11543.3 EEB05060.1 - 0.0044 17.2 0.3 1 9.6 0.4 2.4 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 DUF572 PF04502.8 EEB05060.1 - 0.0045 16.2 18.2 0.0057 15.9 12.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) PB1 PF00564.19 EEB05060.1 - 0.015 14.9 0.1 6.5 6.4 0.0 2.2 2 0 0 2 2 2 0 PB1 domain RA PF00788.18 EEB05060.1 - 0.022 15.2 1.0 0.11 12.9 0.0 2.6 3 1 0 3 3 3 0 Ras association (RalGDS/AF-6) domain zf-C2H2 PF00096.21 EEB05060.1 - 0.033 14.5 0.2 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEB05060.1 - 0.22 11.8 0.9 0.42 10.9 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger double domain Atg14 PF10186.4 EEB05060.1 - 0.28 10.1 19.4 0.48 9.3 13.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LMBR1 PF04791.11 EEB05060.1 - 8.8 4.7 7.5 11 4.4 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Motile_Sperm PF00635.21 EEB05061.2 - 0.011 15.4 0.0 0.043 13.4 0.0 2.0 1 1 0 1 1 1 0 MSP (Major sperm protein) domain Cut8_C PF08559.5 EEB05062.1 - 6.1e-42 142.8 0.3 1e-41 142.1 0.2 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EEB05062.1 - 1.5e-10 40.7 0.9 1.5e-10 40.7 0.7 2.4 2 0 0 2 2 2 1 Cut8 dimerisation domain EFhand_Ca_insen PF08726.5 EEB05062.1 - 0.036 14.0 0.0 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Sugar_tr PF00083.19 EEB05063.1 - 9.7e-122 406.7 26.6 1.1e-121 406.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB05063.1 - 2.5e-24 85.6 37.8 4.1e-21 75.0 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EEB05063.1 - 0.014 15.3 2.2 0.1 12.6 0.0 2.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 TPR_14 PF13428.1 EEB05064.1 - 4.1e-11 42.4 3.0 0.17 12.6 0.0 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 EEB05064.1 - 0.00034 20.4 5.1 0.00089 19.0 0.2 2.6 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EEB05064.1 - 0.025 14.9 0.0 0.81 10.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05064.1 - 0.032 14.6 0.3 11 6.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat APG5 PF04106.7 EEB05065.1 - 8e-52 175.5 0.1 9.7e-52 175.3 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 IGR PF09597.5 EEB05066.1 - 7.7e-20 70.5 0.3 1.1e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 IGR protein motif MFS_1 PF07690.11 EEB05067.1 - 1.6e-37 129.0 20.5 4.6e-37 127.5 14.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Syja_N PF02383.13 EEB05068.1 - 3.2e-85 285.6 0.1 5.2e-85 285.0 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EEB05068.1 - 2.8e-25 89.6 0.1 5.2e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec61_beta PF03911.11 EEB05069.1 - 5.6e-19 67.6 0.7 7.7e-19 67.2 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family ATP_bind_1 PF03029.12 EEB05070.1 - 1.4e-78 263.7 0.0 1.8e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEB05070.1 - 0.00019 20.2 0.0 0.00034 19.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EEB05070.1 - 0.0054 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EEB05070.1 - 0.0078 16.0 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EEB05070.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EEB05070.1 - 0.013 15.1 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EEB05070.1 - 0.035 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EEB05070.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.13 EEB05070.1 - 0.17 10.9 0.0 1.9 7.4 0.0 2.2 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_17 PF13207.1 EEB05070.1 - 0.31 11.8 4.7 0.12 13.2 0.6 2.4 2 1 0 2 2 2 0 AAA domain HSCB_C PF07743.8 EEB05071.1 - 5.6e-19 68.3 3.7 5.6e-19 68.3 2.5 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EEB05071.1 - 3.9e-10 39.3 3.9 4.7e-10 39.0 0.4 2.5 1 1 1 2 2 2 1 DnaJ domain zf-C2H2 PF00096.21 EEB05072.2 - 5.1e-21 73.6 73.3 0.0038 17.4 1.2 9.7 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05072.2 - 3.9e-20 70.6 74.5 0.0011 19.0 1.0 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEB05072.2 - 1.7e-15 56.3 67.5 1.7e-06 28.0 0.2 10.3 10 1 0 10 10 10 5 Zinc-finger double domain YdjO PF14169.1 EEB05072.2 - 0.34 10.3 15.6 1.9 8.0 0.1 5.8 5 1 1 6 6 6 0 Cold-inducible protein YdjO GWT1 PF06423.7 EEB05073.1 - 3.5e-38 130.7 0.7 3.5e-38 130.7 0.5 3.2 4 1 0 4 4 4 1 GWT1 Ribosomal_S17 PF00366.15 EEB05074.1 - 5.4e-31 106.4 1.0 7.8e-31 105.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Rib_5-P_isom_A PF06026.9 EEB05075.1 - 5.1e-57 191.9 0.0 6.8e-57 191.5 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.27 EEB05076.1 - 2.7e-33 112.6 0.9 4.5e-07 29.5 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EEB05076.1 - 3.5e-05 23.6 0.1 0.00071 19.3 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Sec23_trunk PF04811.10 EEB05077.1 - 8.2e-73 244.7 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEB05077.1 - 8.3e-19 66.9 0.2 2.5e-18 65.4 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEB05077.1 - 4.9e-18 65.4 0.0 9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEB05077.1 - 6.9e-12 44.7 5.5 1.2e-11 43.9 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEB05077.1 - 1.4e-07 31.1 0.0 3.6e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Gelsolin repeat Myb_DNA-binding PF00249.26 EEB05078.1 - 9.8e-22 76.7 6.7 1.1e-10 41.3 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB05078.1 - 6.2e-17 61.4 7.5 1.7e-08 34.4 0.0 4.0 3 1 1 4 4 4 2 Myb-like DNA-binding domain Hydrolase_3 PF08282.7 EEB05079.1 - 3.6e-49 167.6 0.0 4.2e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEB05079.1 - 1.5e-11 44.0 0.0 6.3e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EEB05079.1 - 9.2e-05 22.9 0.0 0.0053 17.1 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EEB05079.1 - 0.00059 18.8 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_6 PF13344.1 EEB05079.1 - 0.0015 18.4 0.0 0.0058 16.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB05079.1 - 0.012 15.7 0.0 2.1 8.4 0.0 2.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2088 PF09861.4 EEB05079.1 - 0.036 13.1 0.0 0.097 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2088) Transferase PF02458.10 EEB05080.1 - 1.7e-23 82.7 0.0 1.4e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Transferase family Prp19_bind PF06991.6 EEB05081.1 - 1.3e-65 221.4 31.5 1.3e-65 221.4 21.8 3.0 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF1713 PF08213.6 EEB05082.1 - 3.1e-14 52.2 20.7 3.1e-14 52.2 14.4 1.6 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EEB05082.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial protein Pet20 LCAT PF02450.10 EEB05082.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PTPA PF03095.10 EEB05083.1 - 1.8e-115 385.2 0.0 2.1e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Band_7 PF01145.20 EEB05084.1 - 1.9e-25 89.8 6.2 2e-25 89.7 2.3 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family UcrQ PF02939.11 EEB05085.1 - 2.3e-29 101.0 0.4 2.6e-29 100.8 0.3 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EEB05085.1 - 0.0051 16.9 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) RNase_T PF00929.19 EEB05086.1 - 5.1e-17 62.6 0.2 9.7e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Exonuclease DSPn PF14671.1 EEB05087.1 - 4.5e-50 169.3 0.1 1.1e-48 164.8 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EEB05087.1 - 9.2e-19 67.3 0.0 2.3e-17 62.8 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEB05087.1 - 1.5e-06 27.7 0.0 3.8e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEB05087.1 - 1.5e-05 25.0 0.1 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.7 EEB05087.1 - 0.017 14.5 0.1 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) NYD-SP28 PF14772.1 EEB05087.1 - 0.065 13.3 3.1 0.12 12.4 2.2 1.4 1 0 0 1 1 1 0 Sperm tail DUF382 PF04037.8 EEB05087.1 - 0.074 12.8 0.1 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Y_phosphatase3 PF13350.1 EEB05087.1 - 0.12 12.5 0.4 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Phage_fiber_2 PF03406.8 EEB05087.1 - 0.22 11.1 0.0 0.22 11.1 0.0 2.9 3 0 0 3 3 3 0 Phage tail fibre repeat Ribosomal_L7Ae PF01248.21 EEB05088.1 - 7.9e-27 92.6 1.0 1.1e-26 92.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEB05088.1 - 0.024 14.4 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 APS_kinase PF01583.15 EEB05089.1 - 7.4e-74 246.6 0.0 8.8e-74 246.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EEB05089.1 - 3.9e-09 36.5 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB05089.1 - 5.9e-06 26.6 0.0 1.1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB05089.1 - 1e-05 26.3 0.0 1.4e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEB05089.1 - 9.1e-05 21.7 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EEB05089.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 EEB05089.1 - 0.0061 16.1 0.2 0.17 11.5 0.1 2.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EEB05089.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EEB05089.1 - 0.065 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EEB05089.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein 6PF2K PF01591.13 EEB05089.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF423 PF04241.10 EEB05090.1 - 3e-21 75.1 2.0 4.8e-21 74.4 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) MRP-L46 PF11788.3 EEB05091.1 - 2.9e-15 56.8 0.0 7.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 SCA7 PF08313.7 EEB05092.1 - 3.4e-32 109.8 0.3 1.1e-31 108.2 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain TFIIA PF03153.8 EEB05092.1 - 0.011 15.6 4.5 0.016 15.1 3.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.13 EEB05092.1 - 0.033 12.4 0.5 0.044 12.0 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Phytochelatin_C PF09328.5 EEB05092.1 - 0.04 13.3 0.9 6.8 6.0 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1984) Macoilin PF09726.4 EEB05092.1 - 1.1 7.4 12.1 1.3 7.1 8.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 EEB05092.1 - 2.3 6.4 6.7 3 6.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PseudoU_synth_1 PF01416.15 EEB05093.1 - 7.3e-19 68.1 0.0 9.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.27 EEB05096.1 - 2.2e-35 119.2 28.8 2.2e-07 30.4 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEB05096.1 - 3.4e-05 22.1 1.3 0.064 11.3 0.1 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 RabGAP-TBC PF00566.13 EEB05097.2 - 6.9e-12 45.2 2.5 1.6e-11 44.0 1.7 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.1 EEB05097.2 - 0.00023 21.0 6.9 0.00023 21.0 4.8 4.3 3 2 0 3 3 3 1 Centrosome localisation domain of PPC89 Filament PF00038.16 EEB05097.2 - 0.00036 20.1 18.0 0.0027 17.2 6.4 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF3584 PF12128.3 EEB05097.2 - 0.00038 17.9 11.4 0.00057 17.3 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EEB05097.2 - 0.0013 16.6 19.6 0.0022 15.8 13.6 1.3 1 0 0 1 1 1 1 Myosin tail Cwf_Cwc_15 PF04889.7 EEB05097.2 - 0.0022 17.7 13.6 0.0034 17.1 9.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF869 PF05911.6 EEB05097.2 - 0.0047 15.2 17.1 0.075 11.2 11.9 2.2 1 1 0 1 1 1 1 Plant protein of unknown function (DUF869) Rootletin PF15035.1 EEB05097.2 - 0.0078 16.2 21.0 0.39 10.6 2.5 3.3 1 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 EEB05097.2 - 0.026 13.7 20.3 0.36 9.9 13.8 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EEB05097.2 - 0.027 13.5 18.2 0.051 12.6 12.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 WEMBL PF05701.6 EEB05097.2 - 0.033 12.6 20.6 5 5.4 14.3 2.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF2353 PF09789.4 EEB05097.2 - 0.038 13.2 13.8 0.073 12.3 9.5 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Cast PF10174.4 EEB05097.2 - 0.046 11.7 19.4 0.099 10.6 13.4 1.5 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone AAA_27 PF13514.1 EEB05097.2 - 0.076 10.6 18.9 0.15 9.6 8.5 2.1 1 1 1 2 2 2 0 AAA domain DUF4600 PF15372.1 EEB05097.2 - 0.086 13.0 16.5 0.19 11.9 5.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CENP-F_leu_zip PF10473.4 EEB05097.2 - 0.11 12.3 26.2 0.023 14.5 7.2 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PcfJ PF14284.1 EEB05097.2 - 0.19 11.1 5.9 0.035 13.5 1.1 2.0 2 0 0 2 2 2 0 PcfJ-like protein TMF_DNA_bd PF12329.3 EEB05097.2 - 0.21 11.4 27.4 0.082 12.7 1.1 4.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EEB05097.2 - 0.21 11.3 15.1 13 5.6 0.0 5.1 3 2 1 4 4 4 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 EEB05097.2 - 0.25 11.4 15.1 1.1 9.3 3.2 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EEB05097.2 - 0.36 10.7 7.8 8.5 6.3 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HOOK PF05622.7 EEB05097.2 - 0.62 7.7 22.0 0.59 7.8 12.5 2.3 2 1 1 3 3 3 0 HOOK protein DUF3450 PF11932.3 EEB05097.2 - 0.66 9.1 15.8 1.6 7.9 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 EEB05097.2 - 0.8 9.7 15.7 0.78 9.7 1.2 4.4 2 1 2 4 4 4 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EEB05097.2 - 0.86 9.3 26.7 0.1 12.3 10.8 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 EEB05097.2 - 1.2 8.8 19.9 1.7 8.3 2.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding PilJ PF13675.1 EEB05097.2 - 1.3 9.3 10.0 65 3.8 5.2 3.3 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nup54 PF13874.1 EEB05097.2 - 1.3 8.6 10.5 4.6 6.9 2.4 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF904 PF06005.7 EEB05097.2 - 2.3 8.5 23.2 3.5 8.0 3.4 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF904) IncA PF04156.9 EEB05097.2 - 2.5 7.6 25.1 32 4.0 14.6 3.1 2 1 0 2 2 2 0 IncA protein DUF972 PF06156.8 EEB05097.2 - 2.9 8.2 18.4 5.7 7.3 4.0 3.1 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 EEB05097.2 - 3.4 7.4 8.2 3.1 7.5 2.1 2.4 1 1 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 EEB05097.2 - 6.6 5.5 14.2 45 2.8 10.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EEB05097.2 - 6.7 6.2 19.1 9.1 5.8 0.1 4.1 2 1 0 4 4 3 0 Septum formation initiator HAUS6_N PF14661.1 EEB05097.2 - 8.4 5.6 14.8 2.2 7.5 4.7 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Med9 PF07544.8 EEB05097.2 - 9.4 6.0 9.9 6.3 6.5 3.4 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Ax_dynein_light PF10211.4 EEB05097.2 - 9.6 5.9 24.0 0.054 13.3 5.7 3.4 2 1 2 4 4 3 0 Axonemal dynein light chain Nic96 PF04097.9 EEB05098.1 - 2.6e-168 560.9 3.8 3.9e-168 560.3 2.6 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Bud13 PF09736.4 EEB05099.1 - 8e-43 146.1 4.5 8e-43 146.1 3.1 2.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.7 EEB05100.2 - 2.7e-24 85.4 28.4 9.7e-13 47.3 15.6 2.1 2 0 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GLTSCR1 PF15249.1 EEB05100.2 - 0.025 14.6 1.6 0.077 13.1 1.1 1.8 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region DUF1845 PF08900.6 EEB05100.2 - 0.063 12.5 0.3 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) CDC45 PF02724.9 EEB05100.2 - 0.5 8.3 7.5 0.7 7.8 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Alpha-amylase PF00128.19 EEB05101.1 - 3.5e-58 197.4 2.7 5.5e-58 196.8 1.9 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEB05101.1 - 5.1e-14 52.1 1.3 2e-13 50.2 0.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Aminotran_1_2 PF00155.16 EEB05102.1 - 3.2e-66 223.7 0.0 3.7e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEB05102.1 - 1.7e-06 26.5 0.0 2.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEB05102.1 - 4.9e-05 22.2 0.0 8.7e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEB05102.1 - 0.00011 21.4 0.0 0.00023 20.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF348 PF03990.9 EEB05102.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF348) FA_desaturase PF00487.19 EEB05103.1 - 3.3e-21 75.9 21.1 1.6e-20 73.6 14.6 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EEB05103.1 - 1.5e-06 28.2 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Cyclin_N PF00134.18 EEB05104.2 - 7.5e-12 44.9 0.5 1.2e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 EEB05105.1 - 7.9e-23 80.7 9.8 9.6e-23 80.4 6.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB05105.1 - 1.3e-05 23.9 2.7 2.5e-05 23.0 1.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.7 EEB05105.1 - 5.7e-05 21.6 0.0 8.1e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_2 PF13347.1 EEB05105.1 - 0.00062 18.2 2.1 0.0012 17.2 1.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 EEB05105.1 - 0.0037 15.5 0.2 0.0059 14.8 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3817 PF12823.2 EEB05105.1 - 0.0049 17.2 8.6 0.021 15.2 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3817) SecY PF00344.15 EEB05105.1 - 0.0052 15.7 5.3 0.053 12.4 2.5 2.0 2 0 0 2 2 2 1 SecY translocase OATP PF03137.15 EEB05105.1 - 0.0074 14.3 0.0 0.008 14.2 0.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.8 EEB05105.1 - 0.012 15.9 0.1 0.026 14.8 0.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2140 PF09911.4 EEB05105.1 - 0.037 13.2 0.2 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Cation_efflux PF01545.16 EEB05105.1 - 0.19 10.7 3.1 6 5.8 0.0 2.1 2 0 0 2 2 2 0 Cation efflux family Corona_S2 PF01601.11 EEB05105.1 - 0.53 8.3 1.6 0.75 7.8 1.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CorA PF01544.13 EEB05105.1 - 0.94 8.4 2.7 1.7 7.6 1.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4231 PF14015.1 EEB05105.1 - 1.4 8.9 5.4 0.63 10.0 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3753 PF12575.3 EEB05105.1 - 3 7.6 7.1 0.23 11.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) VHL PF01847.11 EEB05106.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein NMT PF01233.14 EEB05107.1 - 1.2e-76 255.7 0.1 2e-76 255.1 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EEB05107.1 - 7.6e-46 155.8 0.0 1.3e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EEB05107.1 - 0.00075 19.3 0.0 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEB05107.1 - 0.014 15.5 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_His PF13393.1 EEB05108.1 - 8.9e-43 146.5 0.0 2.9e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EEB05108.1 - 1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 EEB05108.1 - 4e-14 52.0 2.3 1.1e-13 50.5 1.6 1.8 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.15 EEB05108.1 - 7.8e-12 44.9 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEB05108.1 - 0.0024 16.7 0.0 0.14 10.8 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EEB05108.1 - 0.028 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) ORF6C PF10552.4 EEB05108.1 - 0.068 12.9 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 ORF6C domain Adaptin_N PF01602.15 EEB05109.1 - 1.1e-106 357.3 7.3 4.8e-84 282.5 0.8 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EEB05109.1 - 4.7e-06 26.7 0.6 4.2 7.7 0.2 4.6 2 2 2 4 4 4 4 HEAT repeats HEAT PF02985.17 EEB05109.1 - 0.0015 18.4 0.6 0.2 11.8 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Mit_ribos_Mrp51 PF11709.3 EEB05110.1 - 5.4e-21 75.1 0.3 4.8e-20 72.0 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit FTHFS PF01268.14 EEB05111.1 - 2e-254 844.7 0.1 2.4e-254 844.5 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EEB05111.1 - 3.3e-67 224.5 1.4 4.9e-67 223.9 0.2 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EEB05111.1 - 2e-39 134.2 0.0 3.9e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AP_endonuc_2 PF01261.19 EEB05111.1 - 0.068 12.4 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ApoO PF09769.4 EEB05111.1 - 0.12 12.0 0.0 1.7 8.3 0.0 2.5 3 0 0 3 3 3 0 Apolipoprotein O Ribonuc_L-PSP PF01042.16 EEB05112.1 - 5.7e-41 139.0 0.2 6.7e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_UL6 PF01763.11 EEB05112.1 - 0.054 11.6 0.0 0.071 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4388 PF14332.1 EEB05112.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) Adaptin_N PF01602.15 EEB05113.2 - 7e-97 324.9 15.7 8.9e-97 324.5 10.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEB05113.2 - 2.3e-08 34.2 0.0 0.00026 21.1 0.0 4.1 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EEB05113.2 - 5.9e-08 32.1 1.5 0.099 12.7 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EEB05113.2 - 3.7e-07 30.1 8.5 2.2e-05 24.4 0.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 EEB05113.2 - 0.00015 20.8 0.5 0.25 10.2 0.0 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EEB05113.2 - 0.00059 19.5 1.6 8.4 6.3 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EEB05113.2 - 0.0014 18.4 1.1 5.3 7.0 0.1 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) RasGEF_N_2 PF14663.1 EEB05113.2 - 0.003 17.4 1.3 0.041 13.8 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Asp PF00026.18 EEB05114.1 - 2.6e-58 197.7 8.3 2.6e-58 197.7 5.8 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEB05114.1 - 2.1e-09 37.5 2.3 7.2e-09 35.8 0.0 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EEB05114.1 - 4.6e-06 26.2 0.3 4.2e-05 23.1 0.1 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal But2 PF09792.4 EEB05115.1 - 7.6e-39 132.7 0.3 1.7e-38 131.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain SNF2_N PF00176.18 EEB05116.2 - 5.6e-56 189.5 0.3 5.6e-56 189.5 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EEB05116.2 - 8.5e-08 31.9 13.9 8.5e-08 31.9 9.6 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB05116.2 - 1.1e-06 28.1 11.5 1.1e-06 28.1 7.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB05116.2 - 1.6e-05 24.7 15.3 1.6e-05 24.7 10.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB05116.2 - 0.00023 20.7 13.6 0.00023 20.7 9.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB05116.2 - 0.00066 19.3 13.1 0.00066 19.3 9.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EEB05116.2 - 0.00095 19.2 8.1 0.00095 19.2 5.6 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger Helicase_C PF00271.26 EEB05116.2 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EEB05116.2 - 2.5 8.0 14.8 1.7 8.5 8.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Telomere_reg-2 PF10193.4 EEB05117.2 - 2.4e-26 92.2 0.1 8.4e-26 90.4 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein DLIC PF05783.6 EEB05118.2 - 0.00053 18.7 0.5 0.59 8.7 0.0 2.9 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) Pap_E4 PF02711.9 EEB05118.2 - 0.026 15.3 0.3 0.079 13.7 0.2 1.9 1 0 0 1 1 1 0 E4 protein PI3Ka PF00613.15 EEB05119.1 - 1.9e-60 203.1 3.2 3.3e-60 202.4 2.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EEB05119.1 - 1.5e-45 155.5 0.0 2.7e-44 151.3 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EEB05119.1 - 3.2e-19 69.1 0.0 5.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 EEB05119.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) WD40 PF00400.27 EEB05120.1 - 7.5e-08 31.9 0.1 7.1e-05 22.5 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEB05120.1 - 0.011 14.5 2.0 0.06 12.0 1.2 2.3 1 1 0 1 1 1 0 Nup133 N terminal like GAS2 PF02187.12 EEB05120.1 - 0.053 13.2 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain TFIIE_alpha PF02002.12 EEB05121.1 - 2.1e-18 65.7 0.4 9e-18 63.7 0.1 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EEB05121.1 - 0.0067 15.7 1.9 0.018 14.3 0.8 2.2 1 1 1 2 2 2 1 TFIIB zinc-binding zf-C2H2_6 PF13912.1 EEB05121.1 - 0.11 12.4 1.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SIN1 PF05422.7 EEB05122.2 - 1e-98 331.1 4.3 1.3e-98 330.7 3.0 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EEB05122.2 - 0.0022 17.8 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG IL12p40_C PF10420.4 EEB05122.2 - 0.051 13.6 0.6 0.93 9.6 0.1 2.5 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Anillin PF08174.6 EEB05123.2 - 1.5e-08 34.7 0.0 6.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EEB05123.2 - 2.6e-08 33.9 0.0 7.5e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 PH domain TFIIS_C PF01096.13 EEB05124.1 - 2.8e-13 49.2 6.7 2.8e-13 49.2 4.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEB05124.1 - 1.9e-11 43.4 3.0 1.9e-11 43.4 2.1 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF3716 PF12511.3 EEB05124.1 - 0.0042 16.6 7.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) DZR PF12773.2 EEB05124.1 - 0.055 13.2 0.3 0.055 13.2 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 EEB05124.1 - 0.11 12.4 8.9 0.43 10.4 1.1 2.3 2 0 0 2 2 2 0 IBR domain ADK_lid PF05191.9 EEB05124.1 - 0.93 9.2 7.2 27 4.5 0.1 3.9 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-CHY PF05495.7 EEB05124.1 - 1.1 9.4 8.5 6.6 6.9 1.5 2.3 2 0 0 2 2 2 0 CHY zinc finger C1_4 PF07975.7 EEB05124.1 - 1.7 8.7 13.7 0.3 11.1 0.5 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain TF_Zn_Ribbon PF08271.7 EEB05124.1 - 2.1 7.7 10.1 0.39 10.0 2.3 3.0 3 1 0 3 3 3 0 TFIIB zinc-binding Cytochrome_C7 PF14522.1 EEB05124.1 - 2.2 7.9 9.6 29 4.3 6.6 2.3 1 1 0 1 1 1 0 Cytochrome c7 zf-BED PF02892.10 EEB05124.1 - 3.4 7.5 0.0 3.4 7.5 0.0 3.2 3 1 0 3 3 3 0 BED zinc finger Lar_restr_allev PF14354.1 EEB05124.1 - 3.4 8.0 7.5 5.4 7.3 1.2 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.1 EEB05124.1 - 3.5 7.3 9.8 7.9 6.2 1.5 3.2 3 1 0 3 3 3 0 Nudix N-terminal Cytochrome_C554 PF13435.1 EEB05124.1 - 4.1 7.4 7.9 0.85 9.6 3.2 1.5 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Elf1 PF05129.8 EEB05124.1 - 5.7 6.7 10.2 6 6.6 0.2 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Cytochrom_NNT PF03264.9 EEB05124.1 - 7.3 5.9 10.9 35 3.7 7.6 2.2 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region P5CR_dimer PF14748.1 EEB05125.2 - 1.8e-22 79.3 1.0 2.9e-22 78.6 0.2 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEB05125.2 - 2.4e-09 37.5 0.1 1.3e-08 35.1 0.1 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF2572 PF10833.3 EEB05126.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) zf-H2C2_2 PF13465.1 EEB05127.1 - 1.1e-06 28.6 17.3 4.4e-06 26.7 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEB05127.1 - 0.00017 21.6 18.8 0.0052 17.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05127.1 - 0.0007 19.7 16.1 0.059 13.7 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEB05127.1 - 0.53 10.5 8.8 11 6.4 0.1 3.0 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEB05127.1 - 5.6 7.0 11.0 10 6.1 4.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_C97 PF05903.9 EEB05128.1 - 1.3e-32 112.6 0.0 1.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EEB05128.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase PqqD PF05402.7 EEB05128.1 - 0.061 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Ecm29 PF13001.2 EEB05129.1 - 2.3e-61 207.8 7.5 4.8e-37 127.6 0.1 3.4 3 0 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 EEB05129.1 - 0.027 14.8 0.2 0.83 10.0 0.0 3.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEB05129.1 - 0.034 14.6 1.6 90 3.7 0.0 6.2 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 EEB05129.1 - 1 9.6 9.6 6.2 7.1 0.0 6.5 8 0 0 8 8 8 0 HEAT repeat Ilm1 PF10311.4 EEB05130.1 - 1.5e-32 112.3 5.3 2.8e-32 111.4 3.7 1.4 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4117 PF13491.1 EEB05130.1 - 6.9 6.0 9.6 11 5.4 0.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4117) Proteasome PF00227.21 EEB05131.1 - 3.3e-34 117.8 0.0 4.2e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_20 PF00982.16 EEB05132.1 - 1.4e-143 478.8 0.4 2e-143 478.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEB05132.1 - 2.3e-35 121.6 0.0 3.3e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Thioredoxin PF00085.15 EEB05133.1 - 2.3e-08 33.6 0.0 2.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 EEB05133.1 - 8e-07 29.0 0.0 0.1 12.4 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin-like domain Metallophos PF00149.23 EEB05134.1 - 3.5e-11 42.8 1.1 1.7e-10 40.6 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 EEB05134.1 - 0.012 13.7 0.0 0.18 9.7 0.0 2.4 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase OSCP PF00213.13 EEB05135.1 - 1.2e-44 152.2 3.9 1.4e-44 151.9 2.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PGM_PMM_I PF02878.11 EEB05136.1 - 1.3e-41 141.3 0.0 2e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEB05136.1 - 2.4e-21 75.9 0.0 6.7e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EEB05136.1 - 9.8e-15 54.5 0.0 2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EEB05136.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Hydrolase_4 PF12146.3 EEB05136.1 - 0.04 13.7 0.4 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_C14 PF00656.17 EEB05137.2 - 9.6e-71 238.3 0.0 1.2e-70 238.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ATP-synt_ab PF00006.20 EEB05138.2 - 2.2e-59 200.5 0.0 3.3e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEB05138.2 - 4.8e-17 62.4 0.1 9.2e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEB05138.2 - 5.5e-12 45.7 1.1 1.1e-11 44.7 0.4 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain TPR_11 PF13414.1 EEB05139.1 - 6e-12 45.0 4.4 4e-06 26.3 1.0 5.1 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EEB05139.1 - 2.3e-08 34.4 10.1 0.0049 17.5 2.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05139.1 - 6.4e-08 32.2 0.7 3.1 8.2 0.1 5.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05139.1 - 3e-05 24.2 11.7 0.35 11.6 0.3 5.8 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05139.1 - 6.3e-05 22.4 3.2 0.28 11.0 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05139.1 - 0.00021 21.5 12.0 0.029 14.6 2.4 4.9 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 EEB05139.1 - 0.00042 20.3 3.6 0.052 13.6 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05139.1 - 0.0011 18.8 11.2 0.29 11.1 1.9 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05139.1 - 0.0017 17.9 1.5 17 5.2 0.3 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEB05139.1 - 0.032 14.0 2.9 0.28 11.0 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05139.1 - 0.23 11.3 4.7 11 6.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05139.1 - 0.32 11.5 3.4 23 5.7 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05139.1 - 0.45 10.5 19.2 3.5 7.7 0.4 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1774 PF08611.5 EEB05140.1 - 5.1e-16 58.6 2.7 5.1e-16 58.6 1.9 3.1 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) DUF3087 PF11286.3 EEB05140.1 - 3 7.0 8.3 3 7.0 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TPR_11 PF13414.1 EEB05141.1 - 4e-42 141.7 33.8 4.8e-08 32.5 0.0 11.6 7 3 4 11 11 11 9 TPR repeat TPR_1 PF00515.23 EEB05141.1 - 8.2e-39 129.6 28.6 8.5e-08 31.4 0.3 14.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05141.1 - 1.6e-34 115.0 42.8 1.4e-07 30.8 0.3 15.2 17 0 0 17 17 15 7 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05141.1 - 1.6e-29 101.6 37.0 1.9e-08 34.1 0.1 10.7 8 3 3 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05141.1 - 1.2e-25 89.6 17.8 0.00039 20.6 0.1 11.2 7 4 6 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05141.1 - 4e-25 85.6 20.9 8.1e-06 25.2 0.1 12.8 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05141.1 - 1e-21 77.0 21.0 0.0064 17.1 0.0 11.1 11 2 1 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05141.1 - 1.2e-19 69.0 22.8 0.00036 20.9 0.1 14.1 10 4 6 16 16 15 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB05141.1 - 4.5e-18 65.1 28.9 4.8e-05 23.4 0.5 8.0 7 2 0 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEB05141.1 - 4.8e-18 64.3 23.2 0.0009 19.5 0.2 10.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05141.1 - 9.9e-13 46.8 19.1 0.0014 18.3 0.1 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05141.1 - 1.4e-11 43.6 14.6 0.55 10.5 0.0 11.9 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB05141.1 - 5e-08 32.6 3.3 6 6.8 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEB05141.1 - 5e-08 32.6 30.6 0.029 14.3 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat PPR PF01535.15 EEB05141.1 - 0.016 15.1 2.8 12 6.1 0.0 5.0 4 0 0 4 4 4 0 PPR repeat TPR_3 PF07720.7 EEB05141.1 - 0.061 13.1 22.3 0.92 9.3 0.2 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF412 PF04217.8 EEB05141.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF412 TPR_4 PF07721.9 EEB05141.1 - 0.097 13.1 3.5 4.1 8.1 0.0 4.3 4 0 0 4 4 2 0 Tetratricopeptide repeat Cbl_N PF02262.11 EEB05141.1 - 0.22 11.2 2.5 1.4 8.6 0.0 3.3 5 0 0 5 5 5 0 CBL proto-oncogene N-terminal domain 1 CAP_GLY PF01302.20 EEB05142.1 - 6.6e-22 77.0 0.3 1.2e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain AhpC-TSA PF00578.16 EEB05143.1 - 2.1e-06 27.4 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family CK_II_beta PF01214.13 EEB05144.2 - 4.5e-78 260.9 0.0 5.7e-78 260.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho86 PF11124.3 EEB05144.2 - 0.08 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 RIC1 PF07064.8 EEB05145.1 - 1e-28 100.4 1.9 2.6e-28 99.1 0.5 2.0 1 1 1 2 2 2 1 RIC1 GRIP PF01465.15 EEB05146.1 - 1.7e-08 33.8 0.1 5.6e-08 32.1 0.1 2.0 1 0 0 1 1 1 1 GRIP domain AAA_13 PF13166.1 EEB05146.1 - 0.0011 17.5 10.1 0.0011 17.5 7.0 4.1 2 1 2 4 4 4 1 AAA domain TPR_MLP1_2 PF07926.7 EEB05146.1 - 0.0017 18.0 9.3 0.0017 18.0 6.5 6.2 4 2 2 6 6 6 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EEB05146.1 - 0.25 10.5 35.6 0.27 10.3 1.2 4.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EEB05146.1 - 2.1 8.2 24.6 0.18 11.7 1.5 5.0 4 3 2 6 6 6 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EEB05146.1 - 8.4 6.2 88.5 0.41 10.4 20.9 5.9 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RRM_2 PF04059.7 EEB05147.2 - 2.4e-51 171.6 1.5 4.4e-51 170.8 1.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EEB05147.2 - 3.1e-13 49.1 0.6 1e-05 25.0 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05147.2 - 2.1e-05 24.3 0.5 0.1 12.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05147.2 - 7e-05 22.6 0.3 0.3 10.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EEB05148.1 - 0.00046 19.4 0.1 0.00073 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal LSM PF01423.17 EEB05149.1 - 2.7e-18 65.2 0.4 3.7e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB05149.1 - 0.0075 16.1 0.1 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EEB05149.1 - 0.071 12.8 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) AA_permease PF00324.16 EEB05151.1 - 9.9e-126 419.8 35.9 1.1e-125 419.6 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB05151.1 - 1.4e-40 139.1 42.3 1.9e-40 138.7 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.16 EEB05151.1 - 0.81 9.3 0.0 0.81 9.3 0.0 3.5 5 0 0 5 5 5 0 Synaptobrevin Pkinase PF00069.20 EEB05152.1 - 4.1e-73 245.7 0.0 4.8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05152.1 - 2.1e-31 108.9 0.0 4e-31 108.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05152.1 - 0.00029 19.9 0.2 0.0027 16.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EEB05152.1 - 0.025 14.3 0.1 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB05152.1 - 0.047 12.5 0.2 0.11 11.2 0.0 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 COX6C PF02937.10 EEB05153.1 - 0.032 14.1 0.3 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc COPI_assoc PF08507.5 EEB05153.1 - 0.048 13.3 0.3 2 8.0 0.0 2.1 2 0 0 2 2 2 0 COPI associated protein ANTH PF07651.11 EEB05154.2 - 7.5e-75 251.2 0.1 7.5e-75 251.2 0.1 4.0 2 1 1 5 5 5 1 ANTH domain I_LWEQ PF01608.12 EEB05154.2 - 2.2e-60 203.0 7.6 2.2e-60 203.0 5.3 6.0 4 2 2 6 6 6 1 I/LWEQ domain TcdB_N PF12918.2 EEB05154.2 - 0.0039 17.2 1.6 0.0039 17.2 1.1 3.4 2 2 2 4 4 4 1 TcdB toxin N-terminal helical domain FlaC_arch PF05377.6 EEB05154.2 - 0.037 13.9 9.3 1.5 8.7 0.4 4.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DNA_pol_B PF00136.16 EEB05155.1 - 5.4e-96 322.1 0.0 8.1e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEB05155.1 - 2.4e-25 89.1 0.2 6.7e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEB05155.1 - 1.4e-09 37.8 10.7 3.9e-09 36.3 7.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Mito_carr PF00153.22 EEB05156.1 - 1.5e-75 249.0 0.7 3.8e-25 87.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 EEB05157.1 - 4e-39 132.4 6.5 6.2e-39 131.7 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e BCNT PF07572.7 EEB05157.1 - 0.18 11.7 1.1 0.3 11.0 0.7 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development Med12 PF09497.5 EEB05158.1 - 9.1e-25 86.4 0.2 3.8e-24 84.4 0.1 2.2 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Slx4 PF09494.5 EEB05160.1 - 4e-16 58.5 0.0 7.7e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Citrate_synt PF00285.16 EEB05160.1 - 0.043 12.5 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase Ish1 PF10281.4 EEB05160.1 - 0.076 13.0 0.5 12 6.0 0.2 2.9 2 1 1 3 3 3 0 Putative stress-responsive nuclear envelope protein GST_N PF02798.15 EEB05161.1 - 9.7e-14 51.3 0.0 3e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEB05161.1 - 1.5e-11 44.0 0.0 3.6e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEB05161.1 - 1.9e-10 40.8 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEB05161.1 - 6.3e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEB05161.1 - 0.00025 20.8 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEB05161.1 - 0.00025 21.4 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydro_lipase PF04083.11 EEB05162.1 - 6.6e-21 73.4 0.0 1.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEB05162.1 - 1e-13 51.3 0.7 2e-13 50.4 0.5 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEB05162.1 - 7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB05162.1 - 0.00021 21.0 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEB05162.1 - 0.042 13.2 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TFIIE_beta PF02186.10 EEB05163.1 - 9.8e-25 86.3 0.6 2e-24 85.3 0.4 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain Clr5 PF14420.1 EEB05164.2 - 1.5e-06 27.9 2.8 1.5e-06 27.9 2.0 2.2 3 0 0 3 3 3 1 Clr5 domain Vel1p PF10339.4 EEB05165.1 - 1.1e-114 380.5 2.8 1.3e-114 380.3 2.0 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive Hanta_nucleocap PF00846.13 EEB05165.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein DUF4646 PF15496.1 EEB05166.1 - 4.5e-38 130.0 0.0 1.1e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EEB05166.1 - 2.7e-05 24.0 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fungal_trans PF04082.13 EEB05167.1 - 5e-23 81.2 2.7 1.2e-22 80.0 1.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEB05167.1 - 1.6e-09 37.5 11.1 0.00072 19.7 3.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05167.1 - 4.9e-08 32.7 11.7 0.00023 21.2 2.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEB05167.1 - 8.2e-05 22.7 1.2 8.2e-05 22.7 0.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EEB05167.1 - 0.00064 19.8 3.6 0.4 10.9 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EEB05167.1 - 0.053 13.1 0.2 0.053 13.1 0.2 2.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EEB05167.1 - 0.45 10.6 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding WWbp PF10349.4 EEB05168.1 - 2.7e-10 41.1 0.0 4.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EEB05168.1 - 8.4e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EEB05168.1 - 0.00028 20.3 0.2 0.0005 19.5 0.2 1.5 1 1 0 1 1 1 1 GRAM domain RuvB_C PF05491.8 EEB05168.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus Abhydrolase_5 PF12695.2 EEB05169.2 - 3.1e-05 23.7 0.0 3.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEB05169.2 - 0.013 14.7 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEB05169.2 - 0.038 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEB05169.2 - 0.12 12.1 0.0 1.1 9.1 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L35Ae PF01247.13 EEB05170.1 - 1.7e-40 136.6 0.2 2e-40 136.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEB05170.1 - 0.0011 18.8 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain PLDc_2 PF13091.1 EEB05172.1 - 1e-12 47.9 0.1 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEB05172.1 - 3.4e-05 23.5 0.5 0.1 12.4 0.0 2.7 2 1 0 2 2 2 2 Phospholipase D Active site motif Pkinase PF00069.20 EEB05173.1 - 2.7e-79 265.9 0.3 1.5e-42 145.5 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EEB05173.1 - 1.7e-66 224.1 12.1 1.7e-66 224.1 8.4 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EEB05173.1 - 2.6e-50 170.9 0.5 1.1e-21 77.0 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EEB05173.1 - 8.6e-20 70.7 0.6 9.4e-19 67.3 0.1 2.9 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.1 EEB05173.1 - 5.9e-14 51.8 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EEB05173.1 - 1.4e-08 34.0 0.0 0.0003 19.8 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEB05173.1 - 9e-05 22.3 0.1 0.024 14.3 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEB05173.1 - 0.00038 19.5 0.0 0.49 9.4 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family NAP PF00956.13 EEB05174.1 - 4.2e-31 107.9 9.6 4.2e-31 107.9 6.7 1.9 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EEB05174.1 - 0.64 10.2 10.5 0.1 12.7 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Syntaxin-6_N PF09177.6 EEB05175.2 - 7.1e-17 61.5 0.3 7.1e-17 61.5 0.2 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EEB05175.2 - 6.1e-09 35.4 0.7 6.1e-09 35.4 0.5 3.0 3 1 0 4 4 4 1 SNARE domain NPV_P10 PF05531.7 EEB05175.2 - 0.0015 18.7 1.3 0.25 11.6 0.0 2.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.3 EEB05175.2 - 0.0052 16.0 1.4 0.0052 16.0 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) MitMem_reg PF13012.1 EEB05175.2 - 0.021 14.9 1.1 4.7 7.3 0.1 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function KicB PF03882.9 EEB05175.2 - 0.049 12.2 3.8 0.23 10.0 0.5 2.1 2 0 0 2 2 2 0 KicB killing factor CCDC-167 PF15188.1 EEB05175.2 - 0.075 12.9 3.4 1.1 9.2 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.7 EEB05175.2 - 0.14 11.9 2.6 4.4 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CASP_C PF08172.7 EEB05175.2 - 0.2 10.6 4.5 0.39 9.7 1.4 2.0 2 0 0 2 2 2 0 CASP C terminal Taxilin PF09728.4 EEB05175.2 - 1 8.3 6.1 0.2 10.6 0.1 2.4 2 1 0 3 3 3 0 Myosin-like coiled-coil protein IncA PF04156.9 EEB05175.2 - 1.1 8.7 13.2 7.9 6.0 3.2 2.4 1 1 1 2 2 2 0 IncA protein Val_tRNA-synt_C PF10458.4 EEB05176.2 - 0.0045 17.0 1.4 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm YlqD PF11068.3 EEB05176.2 - 0.0097 15.9 0.9 0.024 14.6 0.3 1.8 1 1 0 1 1 1 1 YlqD protein ATP-synt_S1 PF05827.7 EEB05176.2 - 0.0097 15.2 3.2 0.012 14.9 2.2 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Endotoxin_N PF03945.9 EEB05176.2 - 0.029 13.7 2.2 0.05 12.9 1.5 1.6 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain Seryl_tRNA_N PF02403.17 EEB05176.2 - 0.037 14.0 0.3 0.037 14.0 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IFP_35_N PF07334.8 EEB05176.2 - 0.043 13.7 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus V-SNARE PF05008.10 EEB05176.2 - 0.05 13.7 2.5 0.062 13.4 0.2 2.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus FlgN PF05130.7 EEB05176.2 - 0.058 13.6 2.0 0.11 12.6 0.6 1.9 1 1 1 2 2 2 0 FlgN protein DUF4618 PF15397.1 EEB05176.2 - 0.061 12.6 4.0 0.13 11.5 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) FAST_1 PF06743.10 EEB05176.2 - 0.15 11.8 2.3 0.4 10.4 0.1 2.5 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Baculo_PEP_C PF04513.7 EEB05176.2 - 0.15 11.8 4.6 5.9 6.7 3.2 2.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EEB05176.2 - 0.22 11.1 8.7 0.44 10.1 6.0 1.6 1 1 0 1 1 1 0 IncA protein DUF4164 PF13747.1 EEB05176.2 - 0.35 11.0 3.5 1.1 9.4 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Bacillus_HBL PF05791.6 EEB05176.2 - 0.49 9.7 8.1 0.14 11.5 1.9 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ING PF12998.2 EEB05176.2 - 1.4 9.2 7.1 6.9 7.0 1.6 3.1 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF904 PF06005.7 EEB05176.2 - 7.6 6.9 8.3 0.76 10.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) FYVE PF01363.16 EEB05177.1 - 1.9e-21 75.7 6.5 1.9e-21 75.7 4.5 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EEB05177.1 - 5.8e-09 35.6 2.9 5.8e-09 35.6 2.0 4.0 3 1 1 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EEB05177.1 - 0.00059 19.8 1.7 0.00059 19.8 1.2 3.4 3 1 1 4 4 4 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEB05177.1 - 0.0054 16.3 1.0 0.0054 16.3 0.7 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EEB05177.1 - 0.0056 16.5 6.2 0.0056 16.5 4.3 3.4 3 1 0 3 3 3 1 IBR domain U-box PF04564.10 EEB05177.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain Lar_restr_allev PF14354.1 EEB05177.1 - 0.15 12.4 11.9 2.4 8.5 0.1 3.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF4637 PF15470.1 EEB05177.1 - 0.21 11.2 2.1 1.4 8.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) zf-RING_5 PF14634.1 EEB05177.1 - 2 8.2 32.2 0.49 10.1 1.7 4.3 4 0 0 4 4 4 0 zinc-RING finger domain DUF4428 PF14471.1 EEB05177.1 - 2.4 7.9 0.0 2.4 7.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) Dus PF01207.12 EEB05178.1 - 9.6e-71 238.1 0.0 1.2e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EEB05178.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Sec63 PF02889.11 EEB05179.1 - 9.6e-29 100.5 0.0 7.5e-24 84.5 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EEB05179.1 - 6.2e-17 61.0 0.5 1.4e-16 59.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Svf1 PF08622.5 EEB05180.1 - 3.6e-44 151.0 0.0 4.2e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Rad60-SLD PF11976.3 EEB05181.1 - 4.8e-27 93.4 0.1 5.7e-18 64.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEB05181.1 - 2.3e-06 26.9 0.2 0.0066 15.8 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin family Rad60-SLD_2 PF13881.1 EEB05181.1 - 0.091 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TAP_C PF03943.8 EEB05182.1 - 8.9e-22 76.2 0.2 2.6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 EEB05182.1 - 5.9e-05 22.5 4.8 0.001 18.6 1.7 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EEB05182.1 - 0.00026 20.5 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EEB05182.1 - 0.0016 18.1 0.5 0.0047 16.6 0.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat UBA_4 PF14555.1 EEB05182.1 - 0.081 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain NTF2 PF02136.15 EEB05182.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.9 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 EEB05182.1 - 0.19 11.8 1.1 38 4.8 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EEB05182.1 - 0.25 11.7 1.6 23 5.7 0.5 3.2 2 0 0 2 2 2 0 Leucine rich repeat GST_N PF02798.15 EEB05183.1 - 2.8e-15 56.2 0.0 7.2e-15 54.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEB05183.1 - 4e-13 49.3 0.0 7.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEB05183.1 - 1.6e-12 47.1 0.0 3.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEB05183.1 - 3.6e-10 39.6 0.0 7.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB05183.1 - 0.0017 18.2 0.1 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M1 PF01433.15 EEB05184.1 - 3.2e-136 454.4 0.2 4.8e-136 453.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EEB05184.1 - 5.7e-83 278.8 0.2 7.9e-83 278.3 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEB05184.1 - 1.8e-19 70.0 0.2 3.5e-19 69.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Glyco_transf_20 PF00982.16 EEB05185.1 - 1.2e-152 508.7 0.0 1.7e-152 508.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEB05185.1 - 2.2e-34 118.4 0.0 5e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Galactosyl_T PF01762.16 EEB05186.1 - 7e-08 32.2 1.3 0.00064 19.3 0.2 3.2 2 1 0 2 2 2 2 Galactosyltransferase Fringe PF02434.11 EEB05186.1 - 0.0016 17.6 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF1325 PF07039.6 EEB05187.1 - 1.3e-28 99.1 0.0 2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 EEB05187.1 - 0.0033 17.2 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Peptidase_S24 PF00717.18 EEB05187.1 - 0.11 12.1 0.1 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 Peptidase S24-like BAR PF03114.13 EEB05188.1 - 5.8e-55 186.3 3.4 7.7e-55 185.8 2.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EEB05188.1 - 5.8e-14 51.2 0.0 1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB05188.1 - 4.3e-13 48.6 0.0 7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEB05188.1 - 1.1e-10 40.7 0.0 1.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pol_alpha_B_N PF08418.5 EEB05188.1 - 0.018 14.5 5.6 0.041 13.4 3.8 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AHS1 PF02682.11 EEB05188.1 - 0.022 14.2 0.4 0.035 13.5 0.3 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 DUF605 PF04652.11 EEB05188.1 - 0.26 10.6 13.8 0.42 9.9 9.6 1.3 1 0 0 1 1 1 0 Vta1 like Herpes_LMP2 PF07415.6 EEB05188.1 - 9.1 4.7 5.9 16 3.9 4.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Aminotran_5 PF00266.14 EEB05189.1 - 2.1e-91 306.4 0.0 2.6e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEB05189.1 - 1.4e-07 30.9 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEB05189.1 - 2.5e-07 30.0 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EEB05189.1 - 0.033 14.0 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Pyridoxal_deC PF00282.14 EEB05189.1 - 0.1 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Bromodomain PF00439.20 EEB05190.1 - 3.6e-17 62.0 0.1 1.1e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Bromodomain zf-rbx1 PF12678.2 EEB05191.1 - 2.6e-09 37.0 3.0 6.5e-09 35.7 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEB05191.1 - 9.4e-09 34.9 7.6 2.5e-08 33.6 5.3 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EEB05191.1 - 4.4e-07 29.7 5.4 1.2e-06 28.3 3.7 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EEB05191.1 - 2.5e-06 27.0 9.5 7.3e-06 25.5 6.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEB05191.1 - 5.7e-06 26.0 2.5 1.6e-05 24.6 1.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EEB05191.1 - 0.0014 18.6 9.0 0.004 17.1 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEB05191.1 - 0.0096 15.9 8.1 0.022 14.8 5.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 EEB05191.1 - 0.025 14.2 6.9 0.066 12.9 4.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB05191.1 - 0.13 12.0 4.3 0.47 10.2 3.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EEB05191.1 - 0.19 11.4 8.6 0.42 10.3 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 EEB05191.1 - 0.57 10.2 7.2 1.5 8.8 5.0 1.8 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 EEB05191.1 - 0.61 9.8 7.9 0.18 11.5 3.1 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.3 EEB05191.1 - 0.84 9.2 4.8 9 5.9 3.4 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EEB05191.1 - 0.89 9.1 9.8 0.31 10.6 4.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF218 PF02698.12 EEB05193.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain WD40 PF00400.27 EEB05195.1 - 4.7e-61 200.6 23.4 4.7e-11 42.1 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EEB05195.1 - 1.3e-16 60.0 2.3 3.6e-16 58.6 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEB05195.1 - 1.3e-11 43.8 2.2 2.9e-11 42.7 1.5 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EEB05195.1 - 1.2e-10 40.1 5.7 0.0016 16.6 0.3 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEB05195.1 - 0.00032 20.4 0.0 0.28 10.9 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 EEB05195.1 - 0.0032 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 PRANC domain Nucleoporin_N PF08801.6 EEB05195.1 - 0.017 13.8 2.6 0.44 9.2 1.5 2.8 1 1 1 2 2 2 0 Nup133 N terminal like La PF05383.12 EEB05197.1 - 3.3e-22 78.0 0.0 5.7e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EEB05197.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB05197.1 - 0.00042 19.8 0.5 0.0008 18.9 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Selenoprotein_S PF06936.6 EEB05197.1 - 9.5 5.7 7.7 6.6 6.2 0.6 2.7 2 1 0 3 3 3 0 Selenoprotein S (SelS) CHCH PF06747.8 EEB05198.2 - 1.1e-06 28.3 6.3 2.2e-06 27.4 4.4 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EEB05198.2 - 0.016 15.3 3.5 0.016 15.3 2.4 1.7 2 0 0 2 2 2 0 GCK domain DHO_dh PF01180.16 EEB05199.1 - 4.4e-94 314.7 0.0 5.1e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EEB05199.1 - 0.0033 16.3 0.0 0.0099 14.7 0.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.12 EEB05199.1 - 0.031 13.5 2.4 0.79 8.9 0.1 2.7 2 1 1 3 3 3 0 PcrB family DNA_ligase_A_M PF01068.16 EEB05200.1 - 7.9e-63 211.4 0.0 1.4e-62 210.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEB05200.1 - 1.5e-52 177.9 0.1 2.5e-52 177.2 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEB05200.1 - 5.1e-23 81.3 0.0 1.5e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DDHD PF02862.12 EEB05201.1 - 3.9e-46 157.6 0.7 2.5e-45 155.0 0.5 2.2 1 1 0 1 1 1 1 DDHD domain LCAT PF02450.10 EEB05201.1 - 0.0047 15.9 0.0 0.01 14.8 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEB05201.1 - 0.024 13.9 0.1 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) MFS_1 PF07690.11 EEB05202.1 - 3.7e-35 121.2 41.5 1.5e-32 112.6 31.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEB05202.1 - 0.012 15.5 2.1 0.012 15.5 1.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1129 PF06570.6 EEB05202.1 - 0.2 10.9 0.1 0.2 10.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Rrn6 PF10214.4 EEB05203.1 - 3.4e-45 154.4 1.6 7.7e-37 126.8 0.4 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor FAD_binding_2 PF00890.19 EEB05204.1 - 7.8e-76 255.5 0.1 9.4e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEB05204.1 - 1e-06 28.1 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEB05204.1 - 1e-06 28.7 1.8 0.00022 21.1 1.4 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB05204.1 - 4.5e-06 26.5 0.9 1.5e-05 24.9 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEB05204.1 - 1.4e-05 24.2 0.1 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEB05204.1 - 4.6e-05 23.5 0.0 8.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEB05204.1 - 0.00045 18.8 10.0 0.00078 18.0 1.2 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 EEB05204.1 - 0.00049 19.0 3.8 0.0012 17.7 0.7 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEB05204.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EEB05204.1 - 0.0093 15.0 0.4 0.014 14.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEB05204.1 - 0.011 14.8 2.5 0.039 13.0 0.4 2.2 2 0 0 2 2 2 0 Thi4 family Vps8 PF12816.2 EEB05205.1 - 3.3e-32 111.3 4.0 9.9e-32 109.7 2.6 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Gifsy-2 PF13856.1 EEB05206.1 - 0.042 13.9 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage FAM177 PF14774.1 EEB05206.1 - 0.38 10.6 4.7 0.098 12.5 1.4 1.4 2 0 0 2 2 2 0 FAM177 family NTR2 PF15458.1 EEB05207.1 - 2.3e-51 174.5 22.2 2.7e-51 174.2 15.4 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF4407 PF14362.1 EEB05207.1 - 0.2 10.6 8.4 0.26 10.2 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3617 PF12276.3 EEB05207.1 - 0.99 8.8 3.6 1.7 8.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) ABC_tran_2 PF12848.2 EEB05207.1 - 2.4 8.0 13.5 0.6 9.9 5.7 2.6 2 0 0 2 2 2 0 ABC transporter Csm1 PF12539.3 EEB05208.2 - 9.4e-20 70.8 0.2 1.9e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 CALCOCO1 PF07888.6 EEB05208.2 - 0.00086 17.7 3.3 0.00094 17.5 1.7 1.4 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 EEB05208.2 - 0.0058 14.5 3.2 0.0065 14.3 2.2 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 EEB05208.2 - 0.0084 15.1 4.0 0.015 14.4 2.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Laminin_II PF06009.7 EEB05208.2 - 0.019 14.7 1.4 0.035 13.8 1.0 1.4 1 0 0 1 1 1 0 Laminin Domain II Spc24 PF08286.6 EEB05208.2 - 0.022 14.4 1.0 0.022 14.4 0.7 2.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.4 EEB05208.2 - 0.024 14.6 3.8 0.043 13.8 2.5 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2201_N PF13203.1 EEB05208.2 - 0.031 13.4 0.6 0.048 12.8 0.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain BLOC1_2 PF10046.4 EEB05208.2 - 0.073 13.2 2.7 1.6 8.8 0.4 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3847 PF12958.2 EEB05208.2 - 0.091 12.5 3.6 0.15 11.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Syntaxin-6_N PF09177.6 EEB05208.2 - 0.096 13.1 3.3 0.29 11.5 2.3 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal YycI PF09648.5 EEB05208.2 - 0.12 11.8 1.7 0.16 11.3 1.2 1.3 1 0 0 1 1 1 0 YycH protein XhlA PF10779.4 EEB05208.2 - 0.18 11.7 0.9 0.47 10.3 0.6 1.7 1 0 0 1 1 1 0 Haemolysin XhlA RNA_polI_A14 PF08203.6 EEB05208.2 - 0.42 10.8 4.4 0.6 10.3 0.6 2.8 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Fib_alpha PF08702.5 EEB05208.2 - 0.53 10.3 4.8 1.2 9.2 2.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EEB05208.2 - 0.74 9.3 12.3 1.4 8.4 8.3 1.6 1 1 1 2 2 2 0 IncA protein SlyX PF04102.7 EEB05208.2 - 2.1 8.7 4.9 1.3 9.4 0.4 2.6 2 1 1 3 3 3 0 SlyX UQ_con PF00179.21 EEB05209.2 - 1.1e-44 151.2 0.0 1.5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEB05209.2 - 0.00028 20.6 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Vezatin PF12632.2 EEB05209.2 - 0.019 14.0 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes RWD PF05773.17 EEB05209.2 - 0.035 14.0 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 EEB05210.1 - 7.5e-13 47.8 10.8 6.5e-06 25.8 0.3 5.3 4 0 0 4 4 4 4 WD domain, G-beta repeat PolC_DP2 PF03833.8 EEB05210.1 - 5.3 4.5 2.6 7.9 4.0 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SRF-TF PF00319.13 EEB05211.1 - 5.5e-19 67.1 0.1 9.4e-19 66.3 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.9 EEB05212.1 - 8.2e-13 47.9 5.9 1.1e-12 47.5 4.1 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA vATP-synt_E PF01991.13 EEB05213.1 - 3.9e-55 186.2 7.0 4.7e-55 185.9 4.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TF_AP-2 PF03299.9 EEB05213.1 - 0.0085 15.6 2.2 0.013 15.0 1.6 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 IL32 PF15225.1 EEB05213.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Interleukin 32 Nse5 PF08691.5 EEB05214.1 - 7.3e-170 565.7 0.3 8.3e-170 565.6 0.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Phosphoprotein PF00922.12 EEB05214.1 - 0.47 9.6 5.9 1 8.5 4.1 1.6 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Y_phosphatase PF00102.22 EEB05215.1 - 7.2e-67 225.1 0.0 9e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEB05215.1 - 8.2e-06 25.9 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EEB05215.1 - 2.5e-05 23.8 0.0 5.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEB05215.1 - 0.00047 20.4 0.0 0.00086 19.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.9 EEB05215.1 - 0.018 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain VanZ PF04892.7 EEB05216.1 - 2.4e-15 56.6 2.5 3.7e-15 56.0 1.8 1.3 1 1 0 1 1 1 1 VanZ like family TctA PF01970.11 EEB05216.1 - 0.067 11.5 0.6 0.083 11.2 0.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Sec7 PF01369.15 EEB05217.2 - 1.1e-31 109.9 0.0 4.7e-31 107.9 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EEB05217.2 - 2e-07 31.2 0.1 6.3e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEB05217.2 - 0.0023 18.1 0.0 0.0073 16.5 0.0 1.9 1 0 0 1 1 1 1 PH domain IpaD PF06511.6 EEB05217.2 - 0.0099 14.9 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 1 Invasion plasmid antigen IpaD 2Fe-2S_thioredx PF01257.14 EEB05218.2 - 1.2e-23 83.3 0.0 1.2e-23 83.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin Glyco_hydro_72 PF03198.9 EEB05219.1 - 1.9e-138 460.7 4.3 2.4e-138 460.3 3.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEB05219.1 - 6.1e-06 25.6 0.1 8.7e-05 21.8 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3808 PF10300.4 EEB05220.1 - 8.1e-95 318.1 3.9 9.7e-95 317.8 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EEB05220.1 - 7.1e-05 22.3 0.6 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EEB05220.1 - 0.00057 19.4 1.2 0.012 15.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05220.1 - 0.0029 17.3 0.1 0.033 14.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05220.1 - 0.0051 16.3 0.0 0.017 14.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat MyTH4 PF00784.12 EEB05220.1 - 0.031 14.2 0.5 0.98 9.3 0.0 3.1 3 0 0 3 3 3 0 MyTH4 domain Ribosomal_L22e PF01776.12 EEB05221.1 - 5.7e-47 158.3 2.3 6.3e-47 158.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family 2OG-FeII_Oxy_2 PF13532.1 EEB05222.1 - 5.8e-16 58.8 0.0 3.4e-15 56.4 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEB05222.1 - 8.3e-09 35.6 0.0 2.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ASXH PF13919.1 EEB05222.1 - 0.054 13.2 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Asx homology domain Imm29 PF15575.1 EEB05222.1 - 0.16 11.5 0.1 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 29 Zip PF02535.17 EEB05223.1 - 5.8e-48 163.5 17.0 5.8e-48 163.5 11.8 2.1 1 1 1 2 2 2 1 ZIP Zinc transporter HSP9_HSP12 PF04119.7 EEB05224.1 - 4.4e-23 81.1 8.2 4.4e-23 81.1 5.7 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 FIVAR PF07554.8 EEB05224.1 - 0.38 11.0 2.1 0.33 11.2 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF883 PF05957.8 EEB05224.1 - 0.62 10.4 3.4 1.5 9.2 2.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EEB05224.1 - 0.72 10.2 7.9 1.6 9.1 5.5 1.7 1 1 0 1 1 1 0 YtxH-like protein DAHP_synth_1 PF00793.15 EEB05225.1 - 9.9e-96 319.5 0.0 1.2e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.19 EEB05226.1 - 4.4e-11 42.1 20.6 6.4e-07 28.9 1.6 3.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EEB05226.1 - 5.2e-08 32.6 0.0 9.3e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB05226.1 - 4.2e-06 26.2 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05226.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 EEB05227.1 - 1.7e-06 27.6 0.3 0.02 14.3 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.1 EEB05228.1 - 3.7e-14 52.6 0.0 5e-10 39.3 0.0 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EEB05228.1 - 1e-13 49.4 0.7 3.3e-05 22.8 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EEB05228.1 - 2.1e-13 48.9 0.0 5.4e-05 22.7 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EEB05228.1 - 2.7e-07 30.3 0.0 0.00013 21.7 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEB05228.1 - 1.5e-06 27.6 1.9 0.0025 17.3 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EEB05228.1 - 4.2e-05 22.7 2.9 0.0076 15.5 0.1 4.0 5 1 0 5 5 5 1 EF hand HEAT PF02985.17 EEB05229.1 - 1.5e-45 149.1 29.9 0.0014 18.4 0.0 14.2 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.1 EEB05229.1 - 1.6e-31 108.4 4.8 4.7e-07 29.9 0.0 6.6 2 1 4 6 6 6 6 HEAT repeats Adaptin_N PF01602.15 EEB05229.1 - 3.2e-11 42.2 2.0 0.00019 19.9 0.0 3.8 2 1 2 4 4 4 4 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EEB05229.1 - 1.5e-10 41.3 4.4 0.16 12.3 0.1 7.5 3 3 6 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEB05229.1 - 6.6e-07 29.6 15.0 8.4 7.0 0.0 9.2 6 3 4 10 10 10 2 HEAT-like repeat Arm PF00514.18 EEB05229.1 - 0.00014 21.5 2.5 4 7.3 0.1 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EEB05229.1 - 0.065 12.9 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CHAD PF05235.9 EEB05229.1 - 0.14 11.7 0.1 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 CHAD domain PRELI PF04707.9 EEB05230.2 - 3.6e-11 42.8 0.0 4.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family GTP1_OBG PF01018.17 EEB05231.2 - 3.4e-41 140.4 3.1 3e-29 101.6 1.5 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EEB05231.2 - 2.9e-21 75.5 0.0 5.7e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB05231.2 - 8e-12 44.7 0.0 2.1e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB05231.2 - 0.00026 20.8 0.0 0.039 13.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EEB05231.2 - 0.00099 18.5 0.1 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EEB05231.2 - 0.0017 17.6 0.1 0.0097 15.1 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 EEB05231.2 - 0.011 16.0 0.0 0.083 13.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 EEB05231.2 - 0.019 14.3 0.2 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 EEB05231.2 - 0.047 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EEB05231.2 - 0.062 12.8 0.0 6.4 6.2 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEB05231.2 - 0.074 11.8 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EEB05231.2 - 0.083 13.3 0.0 0.34 11.4 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Sugar_tr PF00083.19 EEB05232.1 - 1.9e-29 102.5 34.7 5.5e-21 74.6 6.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEB05232.1 - 8.6e-20 70.7 44.4 5.5e-16 58.2 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.15 EEB05232.1 - 0.16 11.6 1.6 1.5 8.5 0.0 3.1 2 0 0 2 2 2 0 Syndecan domain C_GCAxxG_C_C PF09719.5 EEB05232.1 - 1.9 8.2 5.4 27 4.6 0.2 3.0 3 0 0 3 3 3 0 Putative redox-active protein (C_GCAxxG_C_C) EXS PF03124.9 EEB05233.1 - 7.1e-85 285.0 36.5 9.5e-85 284.6 25.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EEB05233.1 - 7.8e-18 65.2 9.0 2.2e-16 60.4 4.8 2.8 2 1 0 2 2 2 2 SPX domain Semialdhyde_dhC PF02774.13 EEB05234.1 - 4.3e-43 147.3 0.0 6.4e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EEB05234.1 - 9.2e-32 109.8 0.0 1.8e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EEB05234.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EEB05234.1 - 0.002 18.6 0.0 0.0078 16.7 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_3 PF03447.11 EEB05234.1 - 0.089 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FAD_binding_6 PF00970.19 EEB05235.1 - 6.8e-30 103.1 0.0 1.1e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEB05235.1 - 2.3e-28 98.9 0.0 3.9e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEB05235.1 - 1.3e-05 25.1 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEB05235.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3127 PF11325.3 EEB05235.1 - 0.068 13.1 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Mob1_phocein PF03637.12 EEB05236.1 - 4.3e-71 238.1 0.1 5.4e-71 237.8 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family ADH_N PF08240.7 EEB05237.1 - 4.8e-30 103.5 0.9 9.7e-30 102.5 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB05237.1 - 2.3e-17 62.7 0.1 4e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB05237.1 - 0.00072 20.4 0.0 0.0015 19.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EEB05237.1 - 0.0078 16.7 0.0 0.074 13.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EEB05237.1 - 0.032 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EEB05237.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEB05237.1 - 0.12 11.7 0.0 0.41 10.0 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EEB05237.1 - 0.15 12.1 0.1 0.5 10.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain GST_N PF02798.15 EEB05238.1 - 7.3e-16 58.1 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEB05238.1 - 2.1e-13 50.3 0.0 3.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEB05238.1 - 6.3e-13 48.5 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEB05238.1 - 3e-12 46.3 0.0 6.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB05238.1 - 3e-09 36.6 0.0 6.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEB05238.1 - 7.3e-06 26.3 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PA14_2 PF10528.4 EEB05239.1 - 1.4e-38 131.2 5.5 7.4e-38 128.9 3.8 2.4 1 0 0 1 1 1 1 GLEYA domain YecM PF06185.7 EEB05239.1 - 0.18 11.0 2.9 2.7e+02 0.6 0.0 6.2 5 2 2 7 7 7 0 YecM protein Fe-ADH PF00465.14 EEB05240.1 - 1.8e-122 408.5 2.4 2e-122 408.3 1.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEB05240.1 - 1e-21 77.4 3.1 5.3e-19 68.4 2.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Lamprin PF06403.6 EEB05240.1 - 0.023 14.4 0.2 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 Lamprin Aldo_ket_red PF00248.16 EEB05241.1 - 3.7e-63 213.0 0.0 4.4e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1b PF00579.20 EEB05242.1 - 1.8e-72 243.9 0.5 2.2e-72 243.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Ada3 PF10198.4 EEB05242.1 - 0.045 13.4 1.7 0.089 12.5 1.1 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Transglut_i_TM PF14400.1 EEB05242.1 - 0.96 8.9 6.3 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices His_Phos_2 PF00328.17 EEB05243.2 - 6.8e-107 357.7 0.3 9.3e-107 357.3 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EEB05243.2 - 1.7e-05 24.3 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EEB05243.2 - 0.00066 19.5 0.3 0.0036 17.1 0.2 2.0 1 1 0 1 1 1 1 ATP-grasp domain CRISPR_Cse2 PF09485.5 EEB05243.2 - 0.081 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Utp21 PF04192.7 EEB05244.1 - 9.5e-62 208.1 3.5 1.3e-61 207.7 2.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EEB05244.1 - 8.1e-26 88.9 13.6 1.9e-08 33.8 0.2 9.5 9 0 0 9 9 9 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEB05244.1 - 0.0053 15.5 5.8 0.14 10.8 0.0 3.4 2 2 0 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EEB05244.1 - 0.017 13.4 0.1 0.2 9.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain ALS_ss_C PF10369.4 EEB05244.1 - 0.1 12.3 0.0 0.47 10.2 0.0 2.1 1 0 0 1 1 1 0 Small subunit of acetolactate synthase Acetyltransf_7 PF13508.1 EEB05245.1 - 3e-12 46.5 0.1 4.7e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB05245.1 - 3.5e-11 42.9 0.0 5.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEB05245.1 - 4.1e-08 33.3 0.0 5.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEB05245.1 - 3e-06 27.2 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB05245.1 - 0.00038 20.3 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Reg_prop PF07494.6 EEB05245.1 - 0.036 14.0 0.0 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 Two component regulator propeller Uds1 PF15456.1 EEB05246.2 - 0.014 15.3 7.4 0.052 13.5 0.1 3.0 2 2 1 3 3 3 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 EEB05246.2 - 0.017 15.1 7.8 0.059 13.3 4.6 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phi-29_GP4 PF05464.6 EEB05246.2 - 0.037 13.9 0.2 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) TBPIP PF07106.8 EEB05246.2 - 0.17 11.4 7.7 0.034 13.7 2.4 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) M PF02370.11 EEB05246.2 - 0.17 12.3 1.9 1.2 9.7 1.0 2.4 2 0 0 2 2 2 0 M protein repeat PHP PF02811.14 EEB05247.1 - 6.6e-23 81.3 0.3 9.2e-23 80.9 0.2 1.2 1 0 0 1 1 1 1 PHP domain zf-CCHC PF00098.18 EEB05248.1 - 8e-11 41.3 8.5 3.2e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EEB05248.1 - 1.6e-06 27.6 0.1 2.9e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEB05248.1 - 2.2e-05 23.9 0.2 5e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EEB05248.1 - 0.00011 21.8 4.5 0.001 18.7 0.6 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EEB05248.1 - 0.0097 15.5 4.2 0.49 10.0 0.2 3.0 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EEB05248.1 - 0.022 14.4 5.3 0.62 9.7 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EEB05248.1 - 5.9 6.4 14.9 0.086 12.3 0.5 3.5 2 1 1 3 3 3 0 Zinc knuckle XPG_I_2 PF12813.2 EEB05249.1 - 1.4e-55 188.5 0.0 1.8e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EEB05249.1 - 0.037 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 XPG I-region zf-CSL PF05207.8 EEB05250.1 - 2e-18 65.6 0.4 2.8e-18 65.1 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EEB05250.1 - 5.6e-06 26.0 0.1 7.5e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Phos_pyr_kin PF08543.7 EEB05251.1 - 3.7e-14 52.5 0.0 6.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEB05251.1 - 2.9e-10 39.7 0.1 1.9e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase SurA_N_2 PF13623.1 EEB05251.1 - 0.043 13.8 0.1 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Fcf1 PF04900.7 EEB05252.1 - 8e-32 109.3 0.2 1.7e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 Fcf1 Ribosomal_L4 PF00573.17 EEB05252.1 - 0.003 16.9 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Asp PF00026.18 EEB05253.1 - 3.5e-54 184.1 11.1 4.4e-54 183.8 7.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEB05253.1 - 1.6e-09 37.9 0.3 1.6e-09 37.9 0.2 2.1 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEB05253.1 - 0.0079 16.6 0.8 1 9.9 0.1 3.5 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EEB05253.1 - 0.061 12.8 2.3 2.4 7.7 0.1 3.4 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal Met_10 PF02475.11 EEB05254.1 - 2.5e-72 242.6 0.0 4.6e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EEB05254.1 - 0.0081 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Pkinase PF00069.20 EEB05255.1 - 3.5e-53 180.4 0.0 2.5e-33 115.3 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05255.1 - 6.9e-23 81.0 0.0 1.5e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EEB05255.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EEB05255.1 - 0.012 14.5 0.1 6.1 5.7 0.0 3.1 3 0 0 3 3 3 0 Kinase-like APH PF01636.18 EEB05255.1 - 0.07 12.8 0.0 0.9 9.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB05255.1 - 0.19 10.7 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_11 PF08241.7 EEB05256.1 - 2.4e-05 24.7 0.0 7.5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEB05256.1 - 0.0002 20.5 0.0 0.00059 19.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EEB05256.1 - 0.0037 17.0 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB05256.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PXPV PF12778.2 EEB05257.1 - 0.11 12.1 2.1 0.18 11.5 1.5 1.3 1 0 0 1 1 1 0 PXPV repeat (3 copies) RRM_1 PF00076.17 EEB05258.1 - 7.6e-43 144.0 1.3 6e-22 77.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05258.1 - 3.7e-36 122.9 0.0 5.7e-18 64.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05258.1 - 3.2e-19 68.5 0.0 2.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EEB05258.1 - 2.7e-05 22.8 60.3 2.9e-05 22.7 41.8 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nup35_RRM_2 PF14605.1 EEB05258.1 - 0.0037 17.0 0.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Fer2_3 PF13085.1 EEB05259.2 - 2.1e-32 111.1 0.1 3.7e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EEB05259.2 - 3.5e-10 40.0 7.0 3.5e-10 40.0 4.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEB05259.2 - 1.8e-08 34.2 5.6 1.8e-08 34.2 3.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEB05259.2 - 0.00025 20.7 5.2 0.00025 20.7 3.6 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEB05259.2 - 0.00089 19.6 2.9 0.00089 19.6 2.0 3.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EEB05259.2 - 0.028 14.8 0.4 0.028 14.8 0.3 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer2 PF00111.22 EEB05259.2 - 0.2 11.4 7.7 0.039 13.6 2.0 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 EEB05259.2 - 0.26 11.5 16.1 5 7.4 0.0 3.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EEB05259.2 - 4.7 7.8 10.0 1.2 9.7 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_7 PF12838.2 EEB05259.2 - 9.3 6.7 19.3 0.62 10.4 7.8 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Arv1 PF04161.8 EEB05260.2 - 7.2e-45 153.4 8.2 9.4e-45 153.0 5.7 1.1 1 0 0 1 1 1 1 Arv1-like family CTNNBL PF08216.6 EEB05260.2 - 0.0023 17.4 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear F-box PF00646.28 EEB05261.1 - 0.00086 18.8 0.0 0.0025 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain Macoilin PF09726.4 EEB05262.1 - 5.4 5.1 8.1 6.9 4.8 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein ALO PF04030.9 EEB05263.1 - 4.6e-68 229.6 3.1 6.1e-68 229.2 2.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EEB05263.1 - 9.3e-30 102.9 0.3 1.3e-29 102.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Aft1_HRA PF11786.3 EEB05264.1 - 2.1e-13 50.3 18.1 5.8e-08 32.8 6.2 3.6 2 1 1 3 3 3 2 Aft1 HRA domain bZIP_1 PF00170.16 EEB05264.1 - 7.4e-11 41.8 3.4 1.3e-10 41.0 2.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EEB05264.1 - 5.2e-08 33.3 6.2 5.2e-08 33.3 4.3 4.6 4 2 2 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EEB05264.1 - 2.7e-06 27.0 5.4 2.7e-06 27.0 3.8 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF3469 PF11952.3 EEB05264.1 - 0.0047 16.5 1.0 0.019 14.6 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3469) C2 PF00168.25 EEB05265.2 - 3.9e-08 33.0 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3102 PF11300.3 EEB05265.2 - 0.098 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) MBF1 PF08523.5 EEB05266.1 - 7.7e-25 86.7 1.9 1.6e-24 85.6 1.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EEB05266.1 - 2.3e-14 52.9 0.2 4.3e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EEB05266.1 - 2.9e-06 27.3 0.2 6.1e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EEB05266.1 - 0.0006 19.8 0.1 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 EEB05266.1 - 0.012 15.3 0.4 0.024 14.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3808 PF10300.4 EEB05267.1 - 7.7e-112 374.2 0.0 9.6e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Rep_fac_C PF08542.6 EEB05269.1 - 7.6e-20 70.6 0.1 6.7e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEB05269.1 - 1.7e-12 47.2 0.1 4.4e-12 45.9 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEB05269.1 - 9.5e-07 29.0 0.5 4.9e-06 26.7 0.2 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB05269.1 - 0.00023 21.3 2.7 0.008 16.3 0.2 3.3 1 1 2 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EEB05269.1 - 0.00039 20.4 0.5 0.046 13.7 0.2 2.8 1 1 1 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 EEB05269.1 - 0.00043 19.0 0.0 0.00087 18.0 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EEB05269.1 - 0.00058 19.8 0.4 0.0026 17.7 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EEB05269.1 - 0.0015 18.1 1.0 0.0025 17.3 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EEB05269.1 - 0.0026 17.3 0.3 0.0062 16.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EEB05269.1 - 0.0032 17.1 1.0 0.23 11.0 0.7 2.4 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_10 PF12846.2 EEB05269.1 - 0.012 15.0 0.2 0.18 11.2 0.1 2.5 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EEB05269.1 - 0.064 13.0 0.1 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 EEB05269.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ANT PF03374.9 EEB05270.2 - 0.066 13.2 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain YdfZ PF14001.1 EEB05270.2 - 0.078 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 YdfZ protein Mito_carr PF00153.22 EEB05271.2 - 1.1e-28 98.7 3.1 3.8e-11 42.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 EEB05272.1 - 4.8e-35 120.4 2.0 4.8e-35 120.4 1.4 2.3 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EEB05272.1 - 1.8e-11 44.1 20.0 1.4e-06 28.3 2.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEB05272.1 - 2.1e-10 40.0 17.4 1e-09 37.7 12.1 1.9 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EEB05272.1 - 0.044 12.8 2.7 0.17 10.9 0.1 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF2012 PF09430.5 EEB05273.1 - 1.4e-22 79.8 0.2 1.9e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.1 EEB05273.1 - 0.002 18.2 0.1 0.0036 17.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EEB05273.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EEB05273.1 - 0.026 14.2 0.0 0.22 11.2 0.0 2.2 2 1 0 2 2 2 0 Cna protein B-type domain GYF PF02213.11 EEB05274.1 - 1e-07 31.4 0.5 2.5e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 GYF domain UPF0228 PF05727.6 EEB05274.1 - 0.057 13.1 0.6 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) CPT PF07931.7 EEB05274.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Ribosomal_L37 PF08561.5 EEB05274.1 - 0.51 9.9 4.1 0.51 9.9 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Caudo_TAP PF02413.12 EEB05274.1 - 3.3 7.8 9.1 0.26 11.4 0.7 2.4 1 1 0 2 2 2 0 Caudovirales tail fibre assembly protein FH2 PF02181.18 EEB05275.1 - 3.1e-74 250.0 1.5 3.1e-74 250.0 1.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EEB05275.1 - 4.5e-22 78.4 3.0 6.4e-21 74.6 0.3 2.8 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EEB05275.1 - 1.3e-12 47.4 0.1 1.3e-12 47.4 0.1 3.1 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Mso1_Sec1_bdg PF14475.1 EEB05276.1 - 1.2e-06 27.8 0.1 2.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 2-Hacid_dh_C PF02826.14 EEB05277.1 - 1.4e-52 177.4 0.0 2.1e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEB05277.1 - 1.4e-07 31.0 0.0 1.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEB05277.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEB05277.1 - 0.0012 18.2 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EEB05277.1 - 0.018 15.1 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.1 EEB05277.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 EEB05277.1 - 0.2 11.4 1.2 1.3 8.8 0.5 2.3 2 1 0 2 2 2 0 ThiF family SOR_SNZ PF01680.12 EEB05278.1 - 5e-117 388.8 5.3 7.7e-117 388.2 3.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EEB05278.1 - 4.3e-08 32.5 2.0 5.7e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EEB05278.1 - 4.2e-05 22.5 0.1 0.1 11.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EEB05278.1 - 0.0015 17.8 0.2 0.3 10.3 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EEB05278.1 - 0.011 14.7 0.4 0.33 9.9 0.0 2.6 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EEB05278.1 - 0.017 14.2 4.2 0.082 12.0 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.19 EEB05278.1 - 0.022 14.1 0.0 3.9 6.7 0.0 2.3 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IGPS PF00218.16 EEB05278.1 - 0.058 12.4 0.1 0.5 9.3 0.0 2.4 2 2 0 2 2 2 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 EEB05278.1 - 0.075 12.1 0.2 2.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Sec16_C PF12931.2 EEB05279.2 - 2.1e-80 270.5 1.6 3.4e-80 269.8 1.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EEB05279.2 - 3e-18 65.9 0.0 7.9e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.3 EEB05279.2 - 0.0028 16.8 0.9 0.0056 15.8 0.6 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Rcd1 PF04078.8 EEB05280.1 - 2.3e-130 433.1 1.1 2.6e-130 432.9 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like CRA PF06589.6 EEB05280.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Methyltransf_26 PF13659.1 EEB05281.1 - 1.8e-13 50.5 0.2 7e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEB05281.1 - 4e-10 39.3 0.0 5.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEB05281.1 - 8.8e-10 38.8 0.1 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB05281.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB05281.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEB05281.1 - 0.00026 20.6 0.0 0.00055 19.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEB05281.1 - 0.00038 19.6 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EEB05281.1 - 0.00092 18.4 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEB05281.1 - 0.0011 19.4 0.2 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EEB05281.1 - 0.0024 17.4 0.0 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 EEB05281.1 - 0.0052 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EEB05281.1 - 0.0052 16.1 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_10 PF05971.7 EEB05281.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) DUF3426 PF11906.3 EEB05281.1 - 0.034 13.8 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Methyltransf_12 PF08242.7 EEB05281.1 - 0.049 14.1 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 EEB05282.1 - 4.2e-49 167.3 0.0 4.9e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEB05282.1 - 8.6e-05 22.4 0.1 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEB05282.1 - 0.0011 18.9 0.0 0.041 13.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEB05282.1 - 0.0014 18.4 0.1 0.011 15.5 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EEB05282.1 - 0.039 12.5 0.1 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EEB05282.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEB05282.1 - 0.14 10.9 0.2 3 6.5 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EEB05282.1 - 0.17 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Thioredoxin PF00085.15 EEB05283.1 - 5.7e-64 212.3 2.6 2.5e-31 107.4 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EEB05283.1 - 1.9e-47 161.4 4.3 2.5e-30 105.6 1.6 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEB05283.1 - 4.4e-17 62.2 6.5 1.5e-07 31.6 0.1 5.5 4 2 1 5 5 5 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEB05283.1 - 1.9e-13 50.3 2.6 7.4e-05 22.7 0.0 4.6 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EEB05283.1 - 1.1e-12 47.7 2.7 0.00014 21.5 0.0 4.3 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EEB05283.1 - 9.7e-12 44.7 1.1 8.9e-05 22.4 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.5 EEB05283.1 - 1.3e-09 37.7 3.1 0.0016 17.9 0.0 3.7 4 0 0 4 4 4 2 Redoxin Thioredoxin_3 PF13192.1 EEB05283.1 - 4.6e-05 23.1 0.3 0.02 14.6 0.1 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EEB05283.1 - 6.6e-05 22.9 5.7 0.057 13.4 0.7 4.0 3 2 1 4 4 4 2 Thioredoxin ERp29_N PF07912.8 EEB05283.1 - 0.0022 17.9 0.3 0.082 12.8 0.0 3.3 3 1 1 4 4 4 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EEB05283.1 - 0.0092 15.5 0.0 4.7 6.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin DUF1450 PF07293.6 EEB05283.1 - 0.015 15.2 0.1 0.058 13.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) TraF PF13728.1 EEB05283.1 - 0.11 11.9 7.0 0.19 11.1 0.0 4.2 4 1 0 5 5 4 0 F plasmid transfer operon protein DUF3384 PF11864.3 EEB05284.1 - 2e-46 158.4 6.3 2e-46 158.4 4.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) WD40 PF00400.27 EEB05285.1 - 6.1e-74 241.4 8.5 2.3e-11 43.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EEB05285.1 - 1.5e-24 85.9 10.6 2.5e-24 85.2 7.4 1.3 1 0 0 1 1 1 1 Tup N-terminal eIF2A PF08662.6 EEB05285.1 - 2.6e-09 37.0 0.1 0.12 12.0 0.0 3.9 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EEB05285.1 - 4.5e-07 29.4 0.6 1.3 8.7 0.0 6.2 7 0 0 7 7 6 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EEB05285.1 - 9e-06 24.6 0.5 0.018 13.7 0.1 3.3 1 1 2 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EEB05285.1 - 9.4e-06 24.0 1.0 2.7 6.0 0.0 4.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEB05285.1 - 0.00012 20.4 0.7 0.0016 16.8 0.1 2.4 2 2 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EEB05285.1 - 0.00075 19.0 0.1 0.13 11.7 0.0 2.6 2 1 0 2 2 2 1 PQQ-like domain Vps16_N PF04841.8 EEB05285.1 - 0.0024 16.4 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region PLC-beta_C PF08703.5 EEB05285.1 - 0.046 13.4 7.4 0.071 12.8 5.1 1.2 1 0 0 1 1 1 0 PLC-beta C terminal AIP3 PF03915.8 EEB05285.1 - 0.058 12.2 6.1 0.082 11.8 4.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Proteasome_A_N PF10584.4 EEB05285.1 - 0.059 12.7 4.9 1.1 8.6 0.0 4.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Phage_lysis PF03245.8 EEB05285.1 - 0.059 13.3 2.6 0.14 12.1 1.8 1.6 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Prefoldin_2 PF01920.15 EEB05285.1 - 0.18 11.5 8.4 0.062 13.0 3.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit Mei5 PF10376.4 EEB05285.1 - 0.33 10.4 8.6 0.063 12.7 3.1 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein Tmemb_cc2 PF10267.4 EEB05285.1 - 0.43 9.1 8.3 0.64 8.5 5.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF342 PF03961.8 EEB05285.1 - 5.8 5.2 7.2 8.5 4.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UQ_con PF00179.21 EEB05287.1 - 6.4e-51 171.4 0.0 7.2e-51 171.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEB05287.1 - 1.6e-06 27.8 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEB05287.1 - 0.037 13.9 0.1 0.051 13.4 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EEB05287.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Sas10_Utp3 PF04000.10 EEB05288.1 - 2.8e-08 33.8 0.7 2.8e-08 33.8 0.5 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family FCH PF00611.18 EEB05288.1 - 4.5 7.5 8.9 0.75 10.0 1.8 2.5 2 2 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RP-C_C PF11800.3 EEB05288.1 - 4.8 6.8 8.5 11 5.6 5.9 1.7 1 1 0 1 1 1 0 Replication protein C C-terminal region Mannosyl_trans2 PF04188.8 EEB05289.1 - 4.4e-79 266.4 31.7 5.1e-77 259.6 22.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Sec62 PF03839.11 EEB05289.1 - 5 6.4 5.3 0.38 10.1 0.2 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 EF-hand_1 PF00036.27 EEB05290.1 - 3.4e-25 85.3 8.1 2.9e-07 29.2 0.1 5.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EEB05290.1 - 1.4e-22 77.4 3.6 2.4e-06 26.9 0.1 5.4 4 1 2 6 6 6 3 EF-hand domain EF-hand_7 PF13499.1 EEB05290.1 - 1.1e-21 76.7 1.8 2.8e-13 49.8 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEB05290.1 - 2.8e-16 58.0 7.8 2.8e-06 26.3 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EEB05290.1 - 1.3e-12 47.1 8.9 0.00011 21.7 0.6 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EEB05290.1 - 3.6e-07 29.8 7.3 0.22 11.2 0.1 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEB05290.1 - 0.00025 21.0 1.8 0.28 11.2 0.1 3.1 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EEB05290.1 - 0.00095 19.0 0.2 0.045 13.6 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain S10_plectin PF03501.10 EEB05290.1 - 0.0035 17.1 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_2 PF09068.6 EEB05290.1 - 0.018 15.0 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 EEB05290.1 - 0.038 13.6 2.0 25 4.6 0.0 4.0 4 1 1 5 5 5 0 EF hand Med4 PF10018.4 EEB05291.1 - 4.9e-22 78.2 0.6 6.4e-22 77.8 0.4 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Exonuc_VII_S PF02609.11 EEB05291.1 - 0.014 15.1 1.3 0.045 13.5 0.5 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit FliD_C PF07195.7 EEB05291.1 - 0.025 13.8 2.0 3.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DASH_Dad2 PF08654.5 EEB05291.1 - 1.4 8.9 4.6 0.81 9.7 0.2 2.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 PCI PF01399.22 EEB05292.1 - 1.6e-11 44.4 0.1 9.1e-11 42.0 0.0 2.4 3 1 0 3 3 3 1 PCI domain TPR_11 PF13414.1 EEB05292.1 - 0.087 12.4 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 EEB05292.1 - 0.15 12.7 0.3 0.51 11.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat EMP70 PF02990.11 EEB05293.1 - 2.5e-174 580.5 12.6 3.1e-174 580.2 8.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 UQ_con PF00179.21 EEB05294.2 - 8.1e-37 125.7 0.2 9.4e-37 125.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rav1p_C PF12234.3 EEB05295.1 - 9.8e-158 526.1 0.1 1.3e-157 525.7 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EEB05295.1 - 7.5e-05 22.4 7.0 0.034 14.0 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat HPS3_N PF14761.1 EEB05295.1 - 0.11 11.8 0.4 0.59 9.5 0.0 2.3 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Histone PF00125.19 EEB05296.1 - 7.7e-32 109.2 0.1 1.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEB05296.1 - 4e-06 26.9 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEB05296.1 - 0.0088 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEB05296.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EEB05297.1 - 7.3e-16 58.0 0.3 8.8e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB05297.1 - 3.3e-06 27.0 0.1 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EEB05297.1 - 2.5e-05 24.1 0.1 3.5e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEB05297.1 - 2.5e-05 24.3 0.1 3.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EEB05297.1 - 0.0049 16.1 0.0 0.0051 16.1 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EEB05297.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EEB05297.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A zf-C2H2 PF00096.21 EEB05298.1 - 5.3e-10 39.0 5.3 6.1e-05 23.1 0.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05298.1 - 2.4e-08 33.7 4.8 0.0017 18.5 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EEB05298.1 - 0.0025 17.9 1.5 0.0044 17.1 1.0 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EEB05298.1 - 0.008 16.4 3.1 0.11 12.8 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain Rpr2 PF04032.11 EEB05300.1 - 3.1e-22 78.2 1.0 4.1e-22 77.8 0.7 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4608 PF15381.1 EEB05300.1 - 0.029 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) zinc_ribbon_5 PF13719.1 EEB05300.1 - 0.15 11.6 3.2 2.6 7.6 0.2 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEB05300.1 - 0.54 10.0 3.9 5.4 6.8 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Histone PF00125.19 EEB05301.1 - 5.1e-31 106.6 0.4 6.7e-31 106.2 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEB05301.1 - 0.00078 19.5 0.1 0.0012 19.0 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEB05301.1 - 0.005 16.8 0.4 0.016 15.2 0.2 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RF-1 PF00472.15 EEB05302.1 - 4e-24 84.6 1.6 5.4e-24 84.1 1.1 1.1 1 0 0 1 1 1 1 RF-1 domain ARD PF03079.9 EEB05303.1 - 2.7e-44 150.8 0.2 3.2e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EEB05303.1 - 8.2e-08 31.6 0.1 1.6e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_8 PF13621.1 EEB05303.1 - 0.004 16.6 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_3 PF05899.7 EEB05303.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_76 PF03663.9 EEB05304.1 - 1.8e-121 405.9 16.5 2.1e-121 405.8 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PQ-loop PF04193.9 EEB05304.1 - 0.13 11.8 1.1 0.53 9.8 0.5 2.1 2 0 0 2 2 2 0 PQ loop repeat NOC3p PF07540.6 EEB05305.2 - 8.7e-29 99.6 0.4 5.9e-28 96.9 0.3 2.6 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EEB05305.2 - 1.6e-23 82.9 5.7 3.1e-23 82.0 0.0 3.2 3 0 0 3 3 3 1 CBF/Mak21 family PFU PF09070.6 EEB05306.2 - 2.5e-43 146.7 2.4 2.7e-43 146.6 0.4 2.0 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EEB05306.2 - 8.7e-43 142.7 24.5 1.7e-08 34.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 EEB05306.2 - 6.1e-27 94.0 0.0 8.6e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EEB05306.2 - 2e-09 37.2 0.0 0.019 14.7 0.0 4.8 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF3639 PF12341.3 EEB05306.2 - 0.076 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) RRM_1 PF00076.17 EEB05307.1 - 2.6e-17 62.1 0.0 4.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05307.1 - 1.2e-12 47.6 0.1 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05307.1 - 5.9e-06 26.0 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.6 EEB05307.1 - 3.6 7.4 18.2 5.8 6.7 12.6 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Zip PF02535.17 EEB05307.1 - 9 5.2 8.3 12 4.7 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PX PF00787.19 EEB05308.1 - 1.9e-28 98.5 0.5 2.2e-28 98.2 0.3 1.1 1 0 0 1 1 1 1 PX domain NAD_binding_9 PF13454.1 EEB05308.1 - 0.076 12.7 0.0 0.096 12.4 0.0 1.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Ribosomal_L14 PF00238.14 EEB05309.1 - 1.2e-42 144.4 0.7 1.4e-42 144.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PK_C PF02887.11 EEB05309.1 - 0.031 13.8 0.4 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain TPR_11 PF13414.1 EEB05310.1 - 0.0099 15.5 0.7 0.014 14.9 0.5 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EEB05310.1 - 0.018 14.9 1.2 0.045 13.6 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2284 PF10050.4 EEB05310.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) TPR_1 PF00515.23 EEB05310.1 - 0.035 13.7 1.1 0.069 12.7 0.8 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SOG2 PF10428.4 EEB05311.1 - 7.9e-61 206.0 12.0 4.6e-40 137.6 0.7 4.2 2 2 1 3 3 3 2 RAM signalling pathway protein LRR_4 PF12799.2 EEB05311.1 - 1.7e-15 56.2 8.1 1.3e-07 31.0 0.2 3.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB05311.1 - 1.4e-11 43.9 9.4 3e-07 30.0 1.4 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EEB05311.1 - 5.9e-09 34.7 7.1 0.11 12.6 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EEB05311.1 - 1.1e-05 24.8 8.3 1.3 9.5 0.0 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EEB05311.1 - 0.004 17.0 1.1 16 5.9 0.1 4.7 4 0 0 4 4 4 1 Leucine Rich repeat Response_reg PF00072.19 EEB05312.2 - 2.7e-22 78.8 0.1 9.3e-16 57.8 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain PseudoU_synth_1 PF01416.15 EEB05313.1 - 9.5e-21 74.2 0.0 1.6e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase STAT_alpha PF01017.15 EEB05314.1 - 0.066 12.9 0.3 0.09 12.4 0.2 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain PI-PLC-X PF00388.14 EEB05315.2 - 6e-58 194.3 0.1 1.6e-57 192.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEB05315.2 - 6.7e-36 122.8 0.0 1.4e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EEB05315.2 - 1.8e-10 40.6 1.9 4.4e-10 39.4 0.3 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EEB05315.2 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EEB05315.2 - 0.00028 20.9 0.1 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEB05315.2 - 0.01 15.0 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 EEB05315.2 - 0.028 14.0 0.1 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EEB05315.2 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EEB05315.2 - 0.13 12.1 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain DUF382 PF04037.8 EEB05316.1 - 1.1e-59 199.8 0.1 1.1e-59 199.8 0.1 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.11 EEB05316.1 - 4.3e-24 83.6 1.9 7.9e-24 82.7 1.3 1.4 1 0 0 1 1 1 1 PSP Nop53 PF07767.6 EEB05317.1 - 1.9e-88 297.0 34.0 1.9e-88 297.0 23.5 1.4 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) CDC27 PF09507.5 EEB05317.1 - 0.0023 17.2 24.0 0.0044 16.3 16.6 1.4 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Herpes_DNAp_acc PF04929.7 EEB05317.1 - 0.93 8.3 10.1 2.1 7.2 7.0 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mem_trans PF03547.13 EEB05317.1 - 1.6 6.9 4.6 2.1 6.5 3.2 1.2 1 0 0 1 1 1 0 Membrane transport protein TMPIT PF07851.8 EEB05317.1 - 5.6 5.9 6.9 11 5.0 4.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein CDC45 PF02724.9 EEB05317.1 - 9.5 4.1 17.7 17 3.2 12.3 1.4 1 0 0 1 1 1 0 CDC45-like protein PAS_10 PF13596.1 EEB05318.1 - 0.035 14.3 0.6 0.21 11.8 0.1 2.6 2 0 0 2 2 2 0 PAS domain DUF3461 PF11944.3 EEB05318.1 - 0.37 10.6 14.5 0.064 13.1 1.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3461) Reo_sigmaC PF04582.7 EEB05318.1 - 0.61 9.2 8.7 0.027 13.6 0.7 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EEB05318.1 - 0.88 9.3 10.0 0.45 10.3 0.7 3.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 EEB05318.1 - 0.99 9.0 49.8 0.49 10.0 4.0 4.4 2 1 2 4 4 4 0 Mnd1 family Nol1_Nop2_Fmu PF01189.12 EEB05319.2 - 1.7e-32 112.9 0.1 6.7e-17 61.7 0.0 3.9 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EEB05319.2 - 0.016 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pinin_SDK_N PF04697.8 EEB05319.2 - 0.11 12.5 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region WD40 PF00400.27 EEB05320.1 - 1.9e-28 97.2 11.6 1.1e-07 31.4 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat CDC45 PF02724.9 EEB05321.2 - 2.8e-214 712.7 5.6 3.2e-214 712.5 3.9 1.0 1 0 0 1 1 1 1 CDC45-like protein DHH PF01368.15 EEB05321.2 - 0.022 14.3 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 DHH family Cation_efflux PF01545.16 EEB05322.1 - 2.7e-58 197.3 5.6 7.2e-58 195.9 3.9 1.7 1 0 0 1 1 1 1 Cation efflux family BTV_NS2 PF04514.7 EEB05322.1 - 0.3 9.9 0.2 0.43 9.4 0.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pox_Ag35 PF03286.9 EEB05322.1 - 2.5 7.5 4.1 4 6.9 2.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Stk19 PF10494.4 EEB05323.1 - 4.7e-34 117.8 0.0 6.8e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NAGLU_C PF12972.2 EEB05323.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain SNF2_N PF00176.18 EEB05323.1 - 0.02 13.6 0.1 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ins_allergen_rp PF06757.8 EEB05323.1 - 0.089 12.2 0.9 0.49 9.8 0.6 1.9 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification AAA PF00004.24 EEB05324.1 - 1.2e-53 180.8 0.0 1.8e-40 138.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EEB05324.1 - 3.7e-12 45.6 0.0 4e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 EEB05324.1 - 1.5e-11 44.0 0.0 7.9e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EEB05324.1 - 3e-08 33.8 0.5 0.0011 19.1 0.1 4.5 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.9 EEB05324.1 - 5.8e-07 29.5 0.0 7.8e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EEB05324.1 - 3.1e-06 27.1 0.0 0.094 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEB05324.1 - 3.9e-06 26.9 0.0 0.0075 16.2 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EEB05324.1 - 6.3e-06 25.8 0.1 0.015 14.9 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 EEB05324.1 - 1.1e-05 24.3 0.1 0.055 12.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EEB05324.1 - 1.8e-05 25.5 0.3 0.0094 16.7 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB05324.1 - 3.9e-05 23.9 0.1 0.042 14.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 EEB05324.1 - 6.6e-05 22.1 0.1 0.0037 16.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEB05324.1 - 8.6e-05 22.2 0.0 0.0011 18.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EEB05324.1 - 0.00019 21.1 0.4 21 4.7 0.0 4.2 2 2 2 4 4 4 0 Archaeal ATPase RuvB_N PF05496.7 EEB05324.1 - 0.0003 19.9 0.1 0.04 12.9 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEB05324.1 - 0.00078 18.8 0.1 0.1 11.9 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EEB05324.1 - 0.0018 18.3 0.0 0.2 11.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 EEB05324.1 - 0.0039 17.0 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEB05324.1 - 0.0053 16.4 0.2 5.3 6.6 0.0 4.0 4 1 0 5 5 5 0 NACHT domain UPF0079 PF02367.12 EEB05324.1 - 0.0067 16.0 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EEB05324.1 - 0.0071 15.4 0.7 0.032 13.3 0.1 2.2 2 1 0 2 2 2 1 KaiC Zeta_toxin PF06414.7 EEB05324.1 - 0.0096 15.0 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 EEB05324.1 - 0.011 16.0 0.8 0.034 14.4 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_24 PF13479.1 EEB05324.1 - 0.017 14.7 0.5 0.06 12.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EEB05324.1 - 0.023 14.2 0.0 0.82 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EEB05324.1 - 0.031 14.2 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEB05324.1 - 0.031 13.6 9.9 0.41 10.0 0.0 4.6 3 2 2 5 5 5 0 AAA domain T2SE PF00437.15 EEB05324.1 - 0.035 13.0 0.1 6 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.12 EEB05324.1 - 0.045 12.6 0.0 0.88 8.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 EEB05324.1 - 0.054 12.9 0.0 0.48 9.8 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EEB05324.1 - 0.1 11.4 0.4 1 8.1 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Response_reg PF00072.19 EEB05325.1 - 4.2e-23 81.4 0.0 3.4e-22 78.5 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EEB05325.1 - 4.8e-20 71.3 0.0 9.3e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EEB05325.1 - 5.4e-19 67.9 0.6 1.6e-18 66.4 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EEB05325.1 - 4.8e-18 65.4 0.0 1.3e-11 44.7 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EEB05325.1 - 3.7e-17 62.2 0.0 4.5e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EEB05325.1 - 1.9e-13 50.2 0.0 6.6e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EEB05325.1 - 1.2e-12 47.7 0.0 2.3e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EEB05325.1 - 1.9e-10 40.2 0.0 0.0025 17.5 0.0 3.6 3 0 0 3 3 3 2 PAS domain GRIP PF01465.15 EEB05325.1 - 0.13 11.8 0.4 14 5.3 0.0 3.1 3 0 0 3 3 3 0 GRIP domain RuBisCO_large PF00016.15 EEB05325.1 - 0.24 10.2 0.0 0.42 9.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Kinesin PF00225.18 EEB05326.1 - 1.8e-109 365.5 0.1 2.3e-109 365.1 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 EEB05326.1 - 0.057 12.8 0.2 0.7 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA-like domain Mo25 PF08569.6 EEB05327.1 - 5.5e-120 400.4 6.8 6.1e-120 400.2 4.7 1.0 1 0 0 1 1 1 1 Mo25-like Glyco_transf_22 PF03901.12 EEB05328.1 - 1.1e-99 334.3 27.6 1.4e-99 333.9 19.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Histone PF00125.19 EEB05329.1 - 7.7e-32 109.2 0.1 1.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEB05329.1 - 4e-06 26.9 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEB05329.1 - 0.0088 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEB05329.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EEB05330.1 - 7.3e-16 58.0 0.3 8.8e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB05330.1 - 3.3e-06 27.0 0.1 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EEB05330.1 - 2.5e-05 24.1 0.1 3.5e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEB05330.1 - 2.5e-05 24.3 0.1 3.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EEB05330.1 - 0.0049 16.1 0.0 0.0051 16.1 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EEB05330.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EEB05330.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A EPSP_synthase PF00275.15 EEB05331.1 - 1e-126 422.8 0.1 1.5e-126 422.2 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EEB05331.1 - 1.5e-96 322.3 0.0 3e-96 321.3 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EEB05331.1 - 8e-64 215.3 0.0 2.5e-63 213.7 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 EEB05331.1 - 5.9e-36 123.7 0.1 5.3e-35 120.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEB05331.1 - 5.2e-25 87.3 0.0 1.3e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEB05331.1 - 3.7e-13 49.7 0.1 9.9e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EEB05331.1 - 5.1e-09 35.7 0.0 4.2e-08 32.8 0.0 2.5 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EEB05331.1 - 1.6e-05 25.7 0.0 5.3e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB05331.1 - 6.1e-05 22.9 0.0 0.2 11.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EEB05331.1 - 0.0054 16.6 0.0 0.054 13.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EEB05331.1 - 0.011 15.9 0.0 0.046 14.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EEB05331.1 - 0.024 14.8 0.0 0.08 13.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Oxidored_nitro PF00148.14 EEB05331.1 - 0.036 12.6 0.0 0.22 10.1 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF258 PF03193.11 EEB05331.1 - 0.081 12.1 0.1 0.2 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 P_gingi_FimA PF06321.6 EEB05331.1 - 0.086 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) eRF1_2 PF03464.10 EEB05332.1 - 3.3e-45 153.6 0.1 5.6e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEB05332.1 - 3.7e-38 130.2 0.2 7.6e-38 129.2 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEB05332.1 - 1.5e-26 92.4 0.0 3.8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 COQ9 PF08511.6 EEB05332.1 - 0.03 13.8 0.1 0.33 10.4 0.0 2.3 1 1 1 2 2 2 0 COQ9 UAA PF08449.6 EEB05333.1 - 7.9e-12 44.7 20.2 9.9e-12 44.3 14.0 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEB05333.1 - 7.8e-10 38.5 7.3 7.8e-10 38.5 5.1 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEB05333.1 - 0.19 11.8 30.8 0.13 12.2 7.4 2.4 2 0 0 2 2 2 0 EamA-like transporter family DUF1240 PF06836.7 EEB05333.1 - 0.24 11.6 4.3 2.7 8.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Recep_L_domain PF01030.19 EEB05334.1 - 8.5e-11 41.8 3.3 0.0029 17.5 0.0 4.1 2 2 2 4 4 4 4 Receptor L domain LRR_5 PF13306.1 EEB05334.1 - 0.00046 19.8 1.2 0.0055 16.4 0.0 2.8 1 1 2 3 3 3 1 Leucine rich repeats (6 copies) DUF4522 PF15022.1 EEB05334.1 - 0.0042 16.7 0.1 0.71 9.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF4522) zf-rbx1 PF12678.2 EEB05335.1 - 8e-37 125.1 12.5 9.8e-37 124.9 8.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEB05335.1 - 2.4e-18 65.7 9.3 3.1e-18 65.3 6.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EEB05335.1 - 5.3e-08 32.5 11.2 2.8e-07 30.2 7.8 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEB05335.1 - 0.00023 20.7 11.4 0.0015 18.1 7.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB05335.1 - 0.00027 20.5 8.9 0.028 14.0 6.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB05335.1 - 0.046 13.7 8.3 0.046 13.7 5.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB05335.1 - 0.051 13.3 9.9 0.28 10.9 6.9 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EEB05335.1 - 0.21 11.7 10.6 8.4 6.6 7.3 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EEB05335.1 - 0.39 10.7 10.0 1 9.3 7.0 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EEB05335.1 - 0.4 10.6 8.9 2.1 8.3 6.3 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEB05335.1 - 0.59 9.9 6.9 16 5.2 4.8 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 EEB05335.1 - 6.3 6.6 7.8 34 4.2 5.4 1.9 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain Pkinase PF00069.20 EEB05336.2 - 4.6e-64 216.0 0.0 5.6e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05336.2 - 3.7e-33 114.7 0.0 5.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05336.2 - 1.7e-05 23.9 0.0 3.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2363 PF10155.4 EEB05337.1 - 0.12 12.3 3.8 0.086 12.7 1.4 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) DUF663 PF04950.7 EEB05338.1 - 2.3e-107 358.4 0.0 2.3e-107 358.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEB05338.1 - 8.6e-21 73.2 0.1 1.8e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Vps39_1 PF10366.4 EEB05339.2 - 1.7e-27 95.5 2.3 1.1e-24 86.4 0.0 3.4 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EEB05339.2 - 6.5e-24 84.2 2.9 7.8e-24 83.9 0.1 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EEB05339.2 - 2.5e-12 46.7 0.2 7.2e-12 45.2 0.1 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EEB05339.2 - 1e-08 34.8 14.2 1.8e-08 34.1 4.0 3.2 3 1 0 3 3 3 2 Region in Clathrin and VPS TPR_19 PF14559.1 EEB05339.2 - 0.045 14.0 1.3 2.5 8.4 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4050 PF13259.1 EEB05340.1 - 1.9e-10 40.7 0.2 2.3e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) T2SM PF04612.7 EEB05341.1 - 0.011 15.5 1.9 0.015 15.0 1.3 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF720 PF05302.6 EEB05341.1 - 0.029 14.1 3.3 0.046 13.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) BCAS2 PF05700.6 EEB05341.1 - 0.064 12.7 1.1 0.077 12.4 0.8 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) MscS_porin PF12795.2 EEB05341.1 - 1 8.6 11.0 1.2 8.3 7.3 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain MRG PF05712.8 EEB05342.2 - 3.5e-46 156.5 0.2 5.7e-46 155.8 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EEB05342.2 - 3.3e-11 42.7 0.3 6.2e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2515 PF10720.4 EEB05342.2 - 0.035 13.0 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) Cnl2_NKP2 PF09447.5 EEB05343.1 - 2.7e-15 55.7 0.1 9.1e-15 54.0 0.1 2.0 1 0 0 1 1 1 1 Cnl2/NKP2 family protein IncA PF04156.9 EEB05343.1 - 0.0081 15.7 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 IncA protein COG2 PF06148.6 EEB05343.1 - 0.036 13.9 0.8 0.036 13.9 0.5 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TFIIE_beta PF02186.10 EEB05343.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain dCMP_cyt_deam_1 PF00383.17 EEB05345.1 - 3.7e-09 36.1 0.1 5.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.1 EEB05345.1 - 0.054 13.2 0.7 0.11 12.3 0.3 1.6 1 1 0 1 1 1 0 OTT_1508-like deaminase D123 PF07065.9 EEB05346.2 - 8.2e-83 277.9 0.0 9.6e-83 277.6 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EEB05346.2 - 0.004 16.9 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) TPR_12 PF13424.1 EEB05347.1 - 2.5e-18 65.7 7.1 3.1e-06 27.0 0.0 4.4 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05347.1 - 8e-14 50.3 7.1 0.00036 20.2 0.3 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05347.1 - 2e-11 43.3 10.0 0.015 14.9 0.0 4.7 3 1 2 5 5 5 4 TPR repeat TPR_14 PF13428.1 EEB05347.1 - 2.5e-10 40.0 3.9 0.1 13.2 0.2 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05347.1 - 2.8e-10 39.3 10.8 0.0095 15.5 0.1 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05347.1 - 3.5e-09 35.7 1.0 0.39 10.6 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05347.1 - 3.7e-09 35.7 8.7 0.19 11.5 0.3 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05347.1 - 1.2e-07 32.2 3.6 0.11 13.1 0.2 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 EEB05347.1 - 4.7e-06 26.0 0.7 0.53 9.6 0.0 3.8 3 1 0 3 3 3 2 26S proteasome subunit RPN7 TPR_19 PF14559.1 EEB05347.1 - 2.1e-05 24.7 5.7 0.016 15.5 0.0 4.5 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05347.1 - 0.00096 19.4 6.2 4.1 8.0 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat 14-3-3 PF00244.15 EEB05347.1 - 0.001 18.2 0.4 0.003 16.6 0.3 1.8 1 0 0 1 1 1 1 14-3-3 protein DUF2225 PF09986.4 EEB05347.1 - 0.0022 17.4 2.1 0.44 9.9 0.1 2.5 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 EEB05347.1 - 0.0065 17.0 1.6 4.9 7.9 0.1 3.2 3 0 0 3 3 2 1 Sel1 repeat MIT PF04212.13 EEB05347.1 - 0.0086 15.9 2.6 4.7 7.1 0.0 4.0 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EEB05347.1 - 0.019 14.9 7.9 2.5 8.1 0.3 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Acetyltransf_5 PF13444.1 EEB05347.1 - 0.098 13.2 0.1 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Apc3 PF12895.2 EEB05347.1 - 0.13 12.4 7.8 4 7.6 1.1 3.6 3 2 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEB05347.1 - 0.81 10.0 5.0 1.9 8.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EEB05348.1 - 1.9e-101 339.1 2.5 1.9e-101 339.1 1.7 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EEB05348.1 - 5.4e-38 128.9 0.2 1.4e-37 127.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EEB05348.1 - 0.0032 17.6 0.2 0.024 14.9 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 EEB05349.2 - 1.4e-67 227.6 0.0 1.7e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05349.2 - 6.8e-35 120.3 0.0 9.6e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEB05349.2 - 9.8e-05 21.5 2.6 0.00021 20.4 1.8 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEB05349.2 - 0.00034 19.6 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EMP24_GP25L PF01105.19 EEB05350.1 - 5.6e-36 123.9 0.0 6.3e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SART-1 PF03343.8 EEB05350.1 - 0.00054 18.4 0.0 0.00067 18.1 0.0 1.0 1 0 0 1 1 1 1 SART-1 family tRNA_Me_trans PF03054.11 EEB05351.2 - 1.3e-109 366.0 0.0 1.4e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EEB05351.2 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EEB05351.2 - 0.051 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 EEB05351.2 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Gln-synt_C PF00120.19 EEB05352.2 - 2e-55 187.7 0.0 5e-48 163.5 0.0 2.1 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEB05352.2 - 1.6e-19 69.2 0.0 2.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SRPRB PF09439.5 EEB05353.1 - 6.4e-29 100.4 0.0 7.9e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEB05353.1 - 2.4e-11 43.1 0.0 5e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB05353.1 - 4.4e-07 29.5 0.0 0.00012 21.5 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEB05353.1 - 3.7e-06 26.2 0.0 5.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEB05353.1 - 8.1e-06 25.7 0.0 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB05353.1 - 4.2e-05 22.8 0.0 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEB05353.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Parvo_NS1 PF01057.12 EEB05353.1 - 0.0063 15.4 0.0 0.0099 14.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 ATP_bind_1 PF03029.12 EEB05353.1 - 0.016 14.7 0.8 0.18 11.3 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EEB05353.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Dynamin_N PF00350.18 EEB05353.1 - 0.02 14.7 0.5 1.3 8.8 0.0 2.5 2 1 1 3 3 3 0 Dynamin family Ras PF00071.17 EEB05353.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_PrkA PF08298.6 EEB05353.1 - 0.066 11.8 0.0 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain AAA_22 PF13401.1 EEB05353.1 - 0.077 13.1 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEB05353.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Wbp11 PF09429.5 EEB05354.1 - 1.7e-18 66.3 13.6 1.7e-18 66.3 9.4 2.4 3 0 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.2 EEB05354.1 - 4.8e-15 55.7 8.1 4.8e-15 55.7 5.6 2.4 3 0 0 3 3 3 1 mRNA biogenesis factor PI3_PI4_kinase PF00454.22 EEB05355.1 - 1.2e-57 195.0 0.2 3.3e-57 193.6 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EEB05355.1 - 8.2e-34 117.1 4.7 1.1e-33 116.6 2.4 2.0 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EEB05355.1 - 3.4e-22 78.4 1.7 3.3e-21 75.2 0.0 3.4 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 EEB05355.1 - 1e-15 56.8 0.1 3.1e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EEB05355.1 - 0.019 14.5 6.2 0.067 12.8 0.1 3.5 3 0 0 3 3 3 0 TPR repeat PDH PF02153.12 EEB05355.1 - 0.021 13.7 0.1 0.04 12.7 0.1 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase SelR PF01641.13 EEB05356.2 - 2e-48 163.1 0.0 2.8e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.1 EEB05356.2 - 0.049 13.8 2.7 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.2 EEB05356.2 - 0.18 11.6 5.7 0.67 9.8 2.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.14 EEB05356.2 - 0.8 9.5 3.7 5.2 6.9 0.5 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e NAD_binding_10 PF13460.1 EEB05357.1 - 9.7e-22 77.8 0.0 1.3e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEB05357.1 - 1.7e-07 30.7 0.1 4.3e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EEB05357.1 - 7.7e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEB05357.1 - 0.0042 16.0 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Mcp5_PH PF12814.2 EEB05359.1 - 2.5e-30 104.9 0.7 7.4e-30 103.3 0.5 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology FUSC PF04632.7 EEB05359.1 - 0.017 13.6 2.2 0.027 12.9 1.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 EEB05359.1 - 1.3 6.7 10.6 2.3 5.9 7.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.4 EEB05359.1 - 3.7 7.7 16.7 1.9 8.6 0.4 3.8 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SMK-1 PF04802.10 EEB05360.1 - 7.7e-69 231.0 5.3 7.7e-69 231.0 3.7 2.9 4 0 0 4 4 4 1 Component of IIS longevity pathway SMK-1 SE PF08491.5 EEB05361.1 - 8.2e-113 375.8 0.1 1.1e-112 375.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EEB05361.1 - 3.7e-12 45.9 0.0 1.1e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEB05361.1 - 6.1e-09 35.2 0.2 6.1e-05 22.0 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EEB05361.1 - 5.6e-06 25.4 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEB05361.1 - 3.1e-05 23.0 1.3 0.01 14.7 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEB05361.1 - 0.00027 20.8 0.5 0.00072 19.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEB05361.1 - 0.0018 17.4 1.2 0.0023 17.0 0.2 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEB05361.1 - 0.003 17.4 0.2 0.0044 16.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB05361.1 - 0.0046 17.3 1.3 0.0073 16.6 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EEB05361.1 - 0.0048 16.3 0.2 0.0089 15.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EEB05361.1 - 0.0065 15.4 0.0 0.049 12.5 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein GDI PF00996.13 EEB05361.1 - 0.012 14.0 0.0 0.02 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.2 EEB05361.1 - 0.013 14.6 0.3 0.017 14.1 0.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEB05361.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EEB05361.1 - 0.02 14.8 0.7 0.08 12.9 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EEB05361.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GMC_oxred_N PF00732.14 EEB05361.1 - 0.04 13.0 0.2 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase 3HCDH_N PF02737.13 EEB05361.1 - 0.13 11.9 0.4 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEB05361.1 - 0.23 9.9 0.4 0.31 9.4 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 EEB05361.1 - 0.4 11.1 1.7 0.7 10.3 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pmp3 PF01679.12 EEB05362.1 - 1.7e-26 91.6 6.6 1.9e-26 91.5 4.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pam16 PF03656.8 EEB05363.1 - 2.5e-22 79.0 4.0 3e-22 78.7 2.8 1.0 1 0 0 1 1 1 1 Pam16 DUF2997 PF11211.3 EEB05364.1 - 0.063 12.6 0.4 0.18 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Nup188 PF10487.4 EEB05365.2 - 2.5e-61 207.7 5.5 7.2e-61 206.2 3.8 1.7 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 GTP_cyclohydro2 PF00925.15 EEB05366.1 - 4.1e-62 208.3 0.1 9.8e-58 194.1 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II tRNA_anti-codon PF01336.20 EEB05367.1 - 0.0031 17.3 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Pkinase PF00069.20 EEB05368.1 - 4.8e-10 39.0 0.0 6.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EEB05368.1 - 2.7e-08 33.1 0.0 5e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EEB05368.1 - 2.2e-07 30.1 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB05368.1 - 1.5e-06 28.1 0.1 0.001 18.8 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EEB05368.1 - 2.8e-06 26.8 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EEB05368.1 - 2.6e-05 23.5 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase NRDE-2 PF08424.5 EEB05368.1 - 0.0004 19.3 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Choline_kinase PF01633.15 EEB05368.1 - 0.0072 15.9 1.8 0.034 13.7 1.3 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase WaaY PF06176.6 EEB05368.1 - 0.02 14.1 0.1 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Clat_adaptor_s PF01217.15 EEB05369.1 - 1.3e-52 177.2 0.7 1.6e-52 176.9 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Clathrin PF00637.15 EEB05370.1 - 1.7e-15 56.8 1.5 1.7e-15 56.8 1.0 3.2 3 1 1 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.27 EEB05370.1 - 7.2e-08 32.0 0.8 0.00036 20.2 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Vps39_2 PF10367.4 EEB05370.1 - 3e-06 27.3 1.2 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 2 HK PF02110.10 EEB05371.1 - 4.3e-80 268.4 0.4 6.6e-80 267.8 0.3 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EEB05371.1 - 1.5e-57 193.6 3.3 2.6e-57 192.8 2.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EEB05371.1 - 0.027 13.7 0.4 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 Carbohydrate kinase Peptidase_M24 PF00557.19 EEB05372.1 - 1.2e-24 87.1 0.1 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4124 PF13511.1 EEB05372.1 - 0.086 12.9 0.2 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DUF1762 PF08574.5 EEB05373.2 - 1.2e-09 38.4 10.1 2.8e-09 37.2 7.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) Ribosomal_L19e PF01280.15 EEB05374.1 - 4.9e-62 208.0 10.8 4.9e-62 208.0 7.5 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e MarR_2 PF12802.2 EEB05374.1 - 0.051 13.2 0.4 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 MarR family Actin PF00022.14 EEB05375.1 - 2.3e-19 69.1 0.1 4.4e-18 64.8 0.0 2.5 1 1 1 2 2 2 1 Actin DRIM PF07539.7 EEB05376.2 - 4.2e-41 139.6 2.2 1.2e-40 138.2 0.1 2.9 2 0 0 2 2 2 1 Down-regulated in metastasis Zn_clus PF00172.13 EEB05377.1 - 0.00064 19.5 11.6 0.0014 18.5 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EEB05381.1 - 2.8e-90 299.3 0.0 1e-44 151.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEB05381.1 - 3.2e-12 46.0 0.0 0.00014 20.9 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEB05381.1 - 9.5e-12 44.8 0.1 7.8e-05 22.4 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEB05381.1 - 1.4e-10 41.3 1.5 0.00084 19.4 0.0 5.1 3 2 0 3 3 3 2 AAA domain AAA_2 PF07724.9 EEB05381.1 - 6e-10 39.2 0.0 0.00021 21.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEB05381.1 - 7.5e-10 39.0 0.9 0.00017 21.6 0.0 4.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EEB05381.1 - 3.8e-08 34.1 0.0 0.0011 19.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEB05381.1 - 3.9e-07 29.6 8.0 0.18 11.1 0.0 4.6 2 2 3 5 5 5 3 AAA domain AAA_14 PF13173.1 EEB05381.1 - 5.1e-07 29.6 0.0 0.0091 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEB05381.1 - 3.5e-06 26.9 0.0 0.071 12.8 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase AAA_33 PF13671.1 EEB05381.1 - 3.7e-06 26.8 0.0 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEB05381.1 - 2.1e-05 24.5 0.1 0.028 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEB05381.1 - 2.4e-05 23.5 0.0 0.11 11.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EEB05381.1 - 4.9e-05 23.0 4.0 0.011 15.5 0.1 3.7 4 0 0 4 4 2 1 Part of AAA domain Mg_chelatase PF01078.16 EEB05381.1 - 5e-05 22.5 0.2 0.1 11.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EEB05381.1 - 7e-05 21.7 0.0 0.27 9.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EEB05381.1 - 0.00012 21.0 0.0 0.15 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EEB05381.1 - 0.00013 21.4 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EEB05381.1 - 0.00019 21.5 0.0 0.79 9.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EEB05381.1 - 0.00027 21.2 0.0 0.061 13.6 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Rad17 PF03215.10 EEB05381.1 - 0.00079 18.2 0.0 0.037 12.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EEB05381.1 - 0.00099 18.7 0.0 1.4 8.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EEB05381.1 - 0.0021 17.6 0.0 0.15 11.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EEB05381.1 - 0.0023 17.5 0.0 0.057 13.0 0.0 2.8 2 2 0 2 2 2 1 Bacterial dnaA protein T2SE PF00437.15 EEB05381.1 - 0.0034 16.3 0.0 2.2 7.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 EEB05381.1 - 0.0036 16.9 2.8 0.0047 16.5 0.0 2.7 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EEB05381.1 - 0.0073 16.6 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEB05381.1 - 0.0082 15.8 0.6 0.68 9.5 0.0 3.4 4 0 0 4 4 3 1 NACHT domain NTPase_1 PF03266.10 EEB05381.1 - 0.014 15.0 0.6 1.2 8.7 0.0 3.5 2 2 2 4 4 4 0 NTPase AAA_24 PF13479.1 EEB05381.1 - 0.017 14.7 1.8 0.51 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EEB05381.1 - 0.018 15.1 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.11 EEB05381.1 - 0.027 13.6 0.1 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase ResIII PF04851.10 EEB05381.1 - 0.031 14.1 0.0 0.53 10.0 0.0 2.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EEB05381.1 - 0.046 13.1 0.0 15 5.0 0.0 3.7 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_23 PF13476.1 EEB05381.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EEB05381.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase KaiC PF06745.8 EEB05381.1 - 0.14 11.2 0.2 15 4.6 0.0 2.9 2 0 0 2 2 2 0 KaiC UPF0079 PF02367.12 EEB05381.1 - 0.14 11.7 0.1 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PUF PF00806.14 EEB05382.2 - 1.7e-20 71.2 0.1 0.001 18.4 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EEB05382.2 - 1.7e-06 27.5 0.0 5.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05382.2 - 1.8e-05 24.5 0.0 4.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05382.2 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlgM PF04316.8 EEB05382.2 - 0.074 12.9 0.0 0.27 11.1 0.0 2.1 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM EnY2 PF10163.4 EEB05382.2 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 CPSase_sm_chain PF00988.17 EEB05383.1 - 2.6e-44 149.9 0.0 3.9e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EEB05383.1 - 5e-44 150.0 0.0 7.4e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEB05383.1 - 1.9e-05 24.1 1.5 0.0045 16.4 1.0 2.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EEB05383.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glycos_transf_2 PF00535.21 EEB05384.1 - 1.7e-27 96.1 0.1 2.2e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEB05384.1 - 1.1e-08 35.1 0.1 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EEB05384.1 - 0.089 13.1 0.1 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Abhydrolase_1 PF00561.15 EEB05385.1 - 2.7e-38 131.8 0.0 4.7e-38 131.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEB05385.1 - 4.1e-10 39.9 0.5 1.6e-09 37.9 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB05385.1 - 0.032 13.9 0.1 1 9.1 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family IlvN PF07991.7 EEB05386.2 - 2.5e-46 157.0 0.1 3.8e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EEB05386.2 - 7e-45 152.5 0.0 1.1e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain CotJA PF11007.3 EEB05386.2 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) Actin PF00022.14 EEB05387.2 - 1.7e-123 411.9 0.0 2e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Actin RLAN PF14401.1 EEB05387.2 - 0.065 12.7 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain HalX PF08663.5 EEB05388.1 - 0.036 14.0 0.5 2.7 8.0 0.3 2.3 2 1 0 2 2 2 0 HalX domain zf-primase PF09329.6 EEB05389.2 - 1.9e-14 52.9 3.4 3.4e-14 52.1 2.4 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EEB05389.2 - 0.00061 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SF3b1 PF08920.5 EEB05389.2 - 0.0019 18.2 0.8 0.0019 18.2 0.6 2.3 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 Mucin PF01456.12 EEB05389.2 - 6.8 6.4 28.0 2 8.1 5.6 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein RNase_H2-Ydr279 PF09468.5 EEB05390.1 - 5.4e-40 137.4 0.0 6.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) RNase_T PF00929.19 EEB05391.1 - 3.1e-33 115.3 0.1 3.7e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 Exonuclease rve_2 PF13333.1 EEB05391.1 - 0.032 14.2 0.1 0.08 13.0 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain DASH_Dam1 PF08653.5 EEB05391.1 - 0.11 12.3 0.1 6.8 6.5 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 Pkinase PF00069.20 EEB05392.2 - 7.4e-32 110.5 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05392.2 - 1.9e-09 37.0 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB05392.2 - 0.0013 18.5 0.0 0.17 11.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DnaJ PF00226.26 EEB05393.2 - 1.7e-28 98.1 1.2 2.7e-28 97.4 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEB05393.2 - 8.7e-16 57.7 14.0 2.5e-15 56.2 9.8 1.7 1 1 1 2 2 2 2 DnaJ central domain CTDII PF01556.13 EEB05393.2 - 1.9e-15 56.4 0.1 1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ C terminal domain Cytochrom_c3_2 PF14537.1 EEB05393.2 - 0.21 11.9 9.2 0.71 10.2 6.4 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EEB05393.2 - 1.2 8.8 11.6 12 5.6 8.1 2.4 1 1 1 2 2 2 0 Cytochrome c7 ADK_lid PF05191.9 EEB05393.2 - 7.5 6.3 12.2 0.13 11.9 1.1 3.1 3 1 1 4 4 4 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 EEB05393.2 - 8.3 6.4 11.5 3.6 7.5 0.4 3.1 2 1 1 3 3 3 0 Zinc ribbon domain Tim54 PF11711.3 EEB05394.1 - 8.3e-66 222.1 0.6 4.6e-64 216.3 0.4 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pil1 PF13805.1 EEB05395.1 - 1e-55 188.8 0.3 1.4e-55 188.3 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 WLM PF08325.5 EEB05396.1 - 1.1e-41 142.7 0.1 2.1e-41 141.8 0.1 1.4 1 1 0 1 1 1 1 WLM domain SprT-like PF10263.4 EEB05396.1 - 0.00036 20.2 0.2 0.00074 19.2 0.1 1.5 1 1 0 1 1 1 1 SprT-like family DUF45 PF01863.12 EEB05396.1 - 0.12 12.1 5.0 0.25 11.1 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF45 NAD_Gly3P_dh_N PF01210.18 EEB05397.1 - 1.5e-56 190.4 0.0 2.3e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEB05397.1 - 1.1e-50 171.2 0.2 2e-50 170.4 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EEB05397.1 - 0.00014 22.2 0.7 0.0015 18.8 0.5 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 EEB05397.1 - 0.0079 15.9 0.0 0.97 9.1 0.0 2.5 2 0 0 2 2 2 1 Rossmann-like domain zf-LYAR PF08790.6 EEB05398.1 - 2.9e-15 55.6 2.8 7.4e-15 54.3 1.9 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Dicty_REP PF05086.7 EEB05398.1 - 0.19 9.4 11.9 0.21 9.2 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Merozoite_SPAM PF07133.6 EEB05398.1 - 0.24 11.2 16.8 0.32 10.8 11.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Macoilin PF09726.4 EEB05398.1 - 0.28 9.4 14.0 0.32 9.2 9.7 1.0 1 0 0 1 1 1 0 Transmembrane protein CCDC32 PF14989.1 EEB05398.1 - 0.29 10.9 13.8 0.13 12.0 7.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing 32 RP-C_C PF11800.3 EEB05398.1 - 1.1 8.9 8.0 1.3 8.6 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CDC45 PF02724.9 EEB05398.1 - 3.5 5.5 16.0 4.2 5.2 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EEB05398.1 - 4.6 7.0 7.9 5.5 6.8 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EEB05398.1 - 7.3 5.1 13.7 8.4 4.9 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 EEB05398.1 - 7.4 6.2 13.2 9.7 5.9 9.2 1.3 1 0 0 1 1 1 0 DDHD domain PWWP PF00855.12 EEB05399.1 - 4.4e-14 52.4 0.2 2.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 EEB05399.1 - 0.0018 17.7 0.2 0.0042 16.5 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CPSase_L_D2 PF02786.12 EEB05400.2 - 6.6e-76 254.2 0.3 2.7e-29 101.9 0.0 3.3 2 1 1 3 3 3 3 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EEB05400.2 - 5.3e-41 139.2 0.0 1e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EEB05400.2 - 1.1e-34 118.8 0.0 1.4e-16 60.5 0.0 3.0 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEB05400.2 - 5.5e-30 104.4 0.1 3.8e-19 69.1 0.0 3.3 2 1 1 3 3 3 3 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEB05400.2 - 1.3e-23 83.3 0.0 8e-12 44.5 0.0 3.6 2 2 1 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEB05400.2 - 5.7e-14 51.8 0.0 1.4e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EEB05400.2 - 8.9e-10 38.3 0.0 1e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEB05400.2 - 1.5e-08 34.2 0.8 5.3e-07 29.2 0.1 2.6 3 0 0 3 3 3 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEB05400.2 - 2e-05 24.4 0.1 0.015 15.1 0.0 3.1 2 1 0 3 3 3 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EEB05400.2 - 0.00068 18.9 0.0 0.097 11.8 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 EEB05400.2 - 0.0022 17.8 0.1 0.0096 15.8 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain GARS_A PF01071.14 EEB05400.2 - 0.0024 17.4 0.8 0.061 12.8 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.16 EEB05400.2 - 0.0043 16.5 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Peptidase_M17_N PF02789.12 EEB05400.2 - 0.011 15.4 0.1 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain ATP-grasp_2 PF08442.5 EEB05400.2 - 0.11 11.8 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Thiolase_N PF00108.18 EEB05401.1 - 1e-93 313.1 5.2 1.4e-93 312.6 3.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEB05401.1 - 2.4e-45 152.9 0.2 8e-45 151.2 0.1 2.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEB05401.1 - 0.023 14.1 1.8 0.023 14.1 1.3 2.6 3 1 1 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain GTP_EFTU PF00009.22 EEB05402.1 - 5.4e-42 143.3 0.0 8e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEB05402.1 - 4.3e-25 87.5 0.0 9.5e-25 86.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEB05402.1 - 1.5e-20 72.8 0.0 3.7e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEB05402.1 - 4e-08 33.2 0.0 8.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EEB05402.1 - 1.9e-06 28.3 0.2 3.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEB05402.1 - 3.3e-06 27.0 0.1 7.2e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EEB05402.1 - 4.7e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EEB05402.1 - 0.0023 17.1 0.1 0.0051 16.0 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EEB05402.1 - 0.098 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.18 EEB05402.1 - 0.11 12.3 0.6 5.2 6.8 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Snf7 PF03357.16 EEB05404.1 - 8.6e-25 87.0 8.8 1.1e-24 86.7 6.1 1.1 1 0 0 1 1 1 1 Snf7 Nnf1 PF03980.9 EEB05405.1 - 2.7e-21 75.5 1.0 2.7e-21 75.5 0.7 2.0 1 1 1 2 2 2 1 Nnf1 TMF_DNA_bd PF12329.3 EEB05405.1 - 0.0002 21.1 3.0 0.00059 19.5 2.1 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TnpV PF14198.1 EEB05405.1 - 0.0021 17.9 2.8 0.18 11.7 0.5 2.3 2 0 0 2 2 2 1 Transposon-encoded protein TnpV Spc7 PF08317.6 EEB05405.1 - 0.0062 15.2 0.6 0.0077 14.9 0.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2937 PF11157.3 EEB05405.1 - 0.0072 15.6 0.3 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.7 EEB05405.1 - 0.012 15.4 0.3 0.031 14.0 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LIF_OSM PF01291.12 EEB05405.1 - 0.018 15.0 0.6 0.037 13.9 0.3 1.6 1 1 0 1 1 1 0 LIF / OSM family ACCA PF03255.9 EEB05405.1 - 0.02 14.4 0.4 0.039 13.5 0.3 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Mnd1 PF03962.10 EEB05405.1 - 0.025 14.2 2.0 0.041 13.5 1.4 1.6 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 EEB05405.1 - 0.066 13.0 0.2 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.10 EEB05405.1 - 0.07 12.6 0.5 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Cob_adeno_trans PF01923.13 EEB05405.1 - 0.074 12.8 0.8 0.11 12.2 0.2 1.5 2 0 0 2 2 2 0 Cobalamin adenosyltransferase IMD PF08397.6 EEB05405.1 - 0.077 12.3 1.4 0.13 11.5 0.3 1.8 1 1 1 2 2 2 0 IRSp53/MIM homology domain Cnl2_NKP2 PF09447.5 EEB05405.1 - 0.091 12.4 2.3 1 9.0 0.0 3.6 4 1 1 5 5 5 0 Cnl2/NKP2 family protein NPV_P10 PF05531.7 EEB05405.1 - 0.13 12.5 0.4 0.33 11.2 0.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EEB05405.1 - 0.16 11.9 4.3 1.7 8.6 3.1 2.3 1 1 0 1 1 1 0 FlxA-like protein Gal4_dimer PF03902.8 EEB05405.1 - 0.18 11.7 1.1 0.59 10.1 0.2 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain End3 PF12761.2 EEB05405.1 - 0.36 10.4 3.4 1.3 8.6 2.4 1.8 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 YlqD PF11068.3 EEB05405.1 - 0.41 10.6 6.8 0.55 10.2 2.6 2.4 2 1 0 2 2 2 0 YlqD protein HR1 PF02185.11 EEB05405.1 - 0.74 9.6 10.3 1.5 8.5 0.7 3.6 3 1 1 4 4 3 0 Hr1 repeat Occludin_ELL PF07303.8 EEB05405.1 - 0.84 10.3 3.8 7.8 7.3 0.4 3.0 1 1 3 4 4 4 0 Occludin homology domain DUF1192 PF06698.6 EEB05405.1 - 1.3 8.8 4.5 2.9 7.7 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) MerR-DNA-bind PF09278.6 EEB05405.1 - 2.5 8.5 10.3 0.86 10.0 1.1 2.9 2 1 1 3 3 2 0 MerR, DNA binding IncA PF04156.9 EEB05405.1 - 2.7 7.5 8.3 1.2 8.7 3.6 2.0 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 EEB05405.1 - 3.8 7.0 9.4 1.6 8.2 1.6 2.7 2 1 1 3 3 3 0 Septum formation initiator PMSR PF01625.16 EEB05406.1 - 4e-58 195.7 0.2 4.7e-58 195.4 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase tRNA-synt_1e PF01406.14 EEB05407.1 - 2.1e-139 463.7 0.2 3.6e-139 463.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEB05407.1 - 1.5e-10 40.2 0.7 7.3e-06 24.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEB05407.1 - 1.2e-06 26.8 0.0 1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EEB05407.1 - 8.4e-05 21.4 0.4 0.0063 15.2 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (K) Herpes_UL37_2 PF07413.6 EEB05407.1 - 0.0031 16.3 0.2 0.0066 15.2 0.1 1.5 1 0 0 1 1 1 1 Betaherpesvirus immediate-early glycoprotein UL37 tRNA-synt_1c PF00749.16 EEB05407.1 - 0.0062 15.2 2.8 0.11 11.0 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain TBP PF00352.16 EEB05408.1 - 7e-70 230.4 0.1 8.4e-35 118.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEB05408.1 - 0.00016 21.6 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) NST1 PF13945.1 EEB05410.1 - 6.6e-70 235.0 8.1 6.6e-70 235.0 5.6 6.1 5 2 2 7 7 7 2 Salt tolerance down-regulator Ras PF00071.17 EEB05411.2 - 7.9e-51 171.6 0.0 9.4e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB05411.2 - 1.6e-16 60.8 0.0 2.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB05411.2 - 3.7e-06 26.3 0.0 5.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB05411.2 - 0.00065 18.9 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEB05411.2 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEB05411.2 - 0.019 14.4 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EEB05411.2 - 0.067 13.1 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase RRM_1 PF00076.17 EEB05412.2 - 9.1e-30 102.1 0.1 7.9e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05412.2 - 6e-20 70.9 0.0 2.4e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05412.2 - 9.3e-13 47.8 0.0 2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEB05412.2 - 0.00081 19.2 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 EEB05412.2 - 0.0047 16.6 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 CTP_transf_1 PF01148.15 EEB05413.2 - 7e-86 288.0 24.1 8.3e-86 287.8 16.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Fumble PF03630.9 EEB05414.1 - 7.5e-134 445.8 0.2 9.5e-134 445.5 0.1 1.1 1 0 0 1 1 1 1 Fumble NCA2 PF08637.5 EEB05415.1 - 7.4e-72 241.6 0.7 1.1e-71 241.0 0.5 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF3353 PF11833.3 EEB05415.1 - 0.032 13.6 0.9 0.071 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) LCD1 PF09798.4 EEB05416.1 - 2.8e-10 38.8 30.7 3.4e-05 22.0 0.1 3.3 1 1 1 2 2 2 2 DNA damage checkpoint protein Ras PF00071.17 EEB05417.1 - 2e-67 225.5 0.2 2.5e-67 225.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB05417.1 - 6.1e-20 71.8 0.1 1.3e-19 70.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEB05417.1 - 2.5e-14 52.8 0.1 3.2e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB05417.1 - 5.7e-07 28.9 0.1 6.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEB05417.1 - 5.8e-05 22.6 0.1 0.00018 21.0 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEB05417.1 - 0.00051 19.9 0.0 0.00076 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEB05417.1 - 0.00053 19.2 0.1 0.00068 18.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EEB05417.1 - 0.0015 18.5 0.3 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 EEB05417.1 - 0.019 14.2 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 EEB05417.1 - 0.028 13.6 0.1 0.063 12.4 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEB05417.1 - 0.041 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EEB05417.1 - 0.048 13.8 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEB05417.1 - 0.053 13.7 0.1 1.3 9.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEB05417.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EEB05417.1 - 0.14 12.4 0.2 0.33 11.2 0.2 1.8 1 1 0 1 1 1 0 ABC transporter Thr_synth_N PF14821.1 EEB05418.1 - 2.1e-28 98.1 0.0 4.8e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EEB05418.1 - 3.4e-22 79.0 0.0 6.9e-22 78.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NARP1 PF12569.3 EEB05419.1 - 0.15 10.8 5.9 0.21 10.2 4.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.14 EEB05419.1 - 4.9 5.7 6.4 6 5.4 4.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein UAA PF08449.6 EEB05420.1 - 5.3e-85 284.9 14.7 6.3e-85 284.7 10.2 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEB05420.1 - 6e-07 29.2 2.5 6e-07 29.2 1.7 2.6 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EEB05420.1 - 2e-06 27.8 6.2 2e-06 27.8 4.3 3.1 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EEB05420.1 - 5.5e-06 25.6 2.1 5.5e-06 25.6 1.5 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EEB05420.1 - 0.015 15.5 6.1 0.015 15.5 4.2 3.2 2 2 2 4 4 4 0 Multidrug resistance efflux transporter DUF4231 PF14015.1 EEB05420.1 - 5.9 6.9 5.9 0.92 9.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) HECT_2 PF09814.4 EEB05421.1 - 5.9e-28 97.6 0.2 7e-28 97.3 0.2 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 EEB05421.1 - 0.037 13.8 0.5 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF4182 PF13790.1 EEB05421.1 - 0.052 13.3 1.4 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) DUF678 PF05077.7 EEB05421.1 - 0.09 12.7 0.4 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-LITAF-like PF10601.4 EEB05421.1 - 0.14 12.0 1.2 29 4.6 0.0 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DnaJ PF00226.26 EEB05422.1 - 2.1e-26 91.4 1.2 3.4e-26 90.7 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEB05422.1 - 1.4e-18 66.5 0.0 6.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEB05422.1 - 8.6e-16 57.7 15.6 1.5e-15 57.0 10.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEB05422.1 - 8.2e-05 22.2 6.9 0.0047 16.6 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 EEB05422.1 - 0.49 10.2 9.1 46 3.9 3.4 3.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2614 PF11023.3 EEB05422.1 - 0.91 9.3 4.7 8.5 6.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Cytochrom_c3_2 PF14537.1 EEB05422.1 - 0.94 9.8 5.7 2.8 8.3 3.9 1.9 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EEB05422.1 - 2 8.0 6.0 0.82 9.3 2.3 1.8 1 1 0 1 1 1 0 Cytochrome c7 zinc-ribbons_6 PF07191.7 EEB05422.1 - 4.2 7.2 9.0 5.7 6.8 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbons Glyco_transf_22 PF03901.12 EEB05423.2 - 4.2e-37 128.1 30.4 5.1e-37 127.8 21.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Inhibitor_I78 PF11720.3 EEB05423.2 - 1.3e-11 44.0 0.0 2.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF3288 PF11691.3 EEB05423.2 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) potato_inhibit PF00280.13 EEB05423.2 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Potato inhibitor I family ATP-synt PF00231.14 EEB05424.1 - 7.5e-63 212.5 8.1 2.5e-62 210.8 5.6 1.7 1 1 0 1 1 1 1 ATP synthase DSBA PF01323.15 EEB05424.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CKS PF01111.14 EEB05425.1 - 1.9e-34 117.2 0.2 2.5e-34 116.9 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 EEB05426.1 - 2.7e-42 142.5 3.2 4.8e-21 74.4 0.5 2.3 2 0 0 2 2 2 2 Bromodomain PAH PF02671.16 EEB05427.1 - 8.6e-36 121.3 11.6 7.4e-14 51.1 0.6 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EEB05427.1 - 2.1e-16 59.5 0.1 5e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Chitin_synth_1 PF01644.12 EEB05428.1 - 2e-48 164.2 0.2 3.1e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEB05428.1 - 3.4e-21 74.7 0.0 8.6e-21 73.4 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEB05428.1 - 2.8e-05 22.7 0.5 2.8e-05 22.7 0.3 1.9 2 0 0 2 2 2 1 Chitin synthase CDP-OH_P_tran_2 PF08009.6 EEB05428.1 - 9.3 6.0 9.8 0.72 9.6 2.7 2.2 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 tRNA-synt_1 PF00133.17 EEB05429.1 - 1.1e-216 720.5 0.0 9.1e-216 717.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEB05429.1 - 9.2e-33 113.1 0.9 1.9e-32 112.1 0.6 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEB05429.1 - 4.3e-21 75.0 0.0 1.6e-11 43.5 0.0 4.8 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEB05429.1 - 8.8e-12 44.6 5.5 1.6e-08 34.0 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EEB05429.1 - 4.8e-05 22.3 0.5 0.0088 14.8 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EEB05429.1 - 0.00052 19.2 0.0 0.17 10.9 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 EEB05429.1 - 0.065 12.3 0.1 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF837 PF05769.6 EEB05429.1 - 0.082 12.4 0.2 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF837) tRNA-synt_1c PF00749.16 EEB05429.1 - 0.11 11.1 0.0 0.11 11.1 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain ATP-synt_B PF00430.13 EEB05429.1 - 0.47 10.2 7.6 1 9.1 5.3 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Amidohydro_4 PF13147.1 EEB05430.1 - 1.8e-07 31.5 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EEB05430.1 - 2.8e-07 30.3 0.0 5.7e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEB05430.1 - 0.0021 17.7 0.0 0.045 13.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.11 EEB05431.1 - 5.8e-23 81.1 21.5 5.8e-23 81.1 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chlam_PMP PF02415.12 EEB05431.1 - 0.0071 16.5 1.2 0.063 13.5 0.0 2.6 2 0 0 2 2 2 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Cwf_Cwc_15 PF04889.7 EEB05432.1 - 6.4e-70 235.6 25.1 8e-70 235.3 17.4 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.13 EEB05432.1 - 0.026 13.7 15.2 0.04 13.0 10.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region PA26 PF04636.8 EEB05432.1 - 0.043 12.5 9.3 0.055 12.1 6.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PAS PF00989.19 EEB05432.1 - 0.072 12.8 1.3 0.17 11.7 0.9 1.6 1 0 0 1 1 1 0 PAS fold CDC45 PF02724.9 EEB05432.1 - 0.1 10.6 20.7 0.13 10.2 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 EEB05432.1 - 0.42 9.9 17.4 0.53 9.5 12.1 1.2 1 0 0 1 1 1 0 SprA-related family Kisspeptin PF15152.1 EEB05432.1 - 0.59 10.8 4.8 0.23 12.1 0.5 2.2 2 0 0 2 2 2 0 Kisspeptin Hid1 PF12722.2 EEB05432.1 - 0.96 7.0 15.4 1 6.9 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 EEB05432.1 - 1.9 6.8 4.4 2.2 6.5 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.7 EEB05432.1 - 3.1 6.6 8.2 3.8 6.3 5.7 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Astro_capsid PF03115.9 EEB05432.1 - 3.1 5.9 10.2 3.4 5.8 7.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NOA36 PF06524.7 EEB05432.1 - 3.4 6.8 12.3 4.6 6.4 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein Usp PF00582.21 EEB05432.1 - 4.4 7.5 5.9 10 6.3 1.1 2.4 2 0 0 2 2 2 0 Universal stress protein family Cpn60_TCP1 PF00118.19 EEB05433.2 - 3.2e-143 477.8 5.9 3.6e-143 477.7 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_5 PF07728.9 EEB05433.2 - 0.077 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CTD_bind PF04818.8 EEB05434.1 - 5.2e-18 65.0 0.3 5.2e-18 65.0 0.2 2.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EEB05434.1 - 0.022 14.3 1.2 0.039 13.5 0.3 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 COX17 PF05051.8 EEB05435.1 - 5e-21 74.4 6.4 6e-21 74.1 4.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Dermcidin PF15291.1 EEB05435.1 - 0.1 12.7 1.0 0.11 12.6 0.7 1.1 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF1690 PF07956.6 EEB05435.1 - 0.16 11.9 1.4 0.17 11.8 1.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1903 PF08991.5 EEB05435.1 - 0.28 11.3 5.3 0.65 10.2 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Nt_Gln_amidase PF09764.4 EEB05436.2 - 8.3e-51 171.8 0.1 1e-50 171.6 0.1 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase Peptidase_M14 PF00246.19 EEB05437.1 - 3.3e-69 233.6 0.1 4.4e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SelP_N PF04592.9 EEB05437.1 - 0.029 13.7 2.7 0.048 13.0 1.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ubiquitin PF00240.18 EEB05438.1 - 3.1e-169 548.6 31.3 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 EEB05438.1 - 3.7e-97 318.0 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB05438.1 - 1.7e-29 101.8 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB05438.1 - 6.8e-27 94.1 2.6 0.0015 18.2 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB05438.1 - 6.9e-17 61.3 5.0 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEB05438.1 - 1e-16 60.8 4.6 0.18 11.9 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEB05438.1 - 2.5e-13 49.8 0.0 2 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EEB05438.1 - 8.1e-08 31.6 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 EEB05438.1 - 2e-07 30.8 9.3 6.4 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 EEB05438.1 - 1.6e-05 24.5 8.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 EEB05438.1 - 0.00014 21.3 0.0 65 2.8 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EEB05438.1 - 0.00026 19.4 18.8 3.1 5.9 0.2 6.8 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 EEB05438.1 - 0.00039 20.7 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CpeT PF06206.6 EEB05438.1 - 0.0072 16.0 0.2 1.4e+02 2.0 0.0 4.6 1 1 4 5 5 5 0 CpeT/CpcT family (DUF1001) CTDII PF01556.13 EEB05438.1 - 0.019 14.8 19.9 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 EEB05438.1 - 0.026 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 EEB05438.1 - 0.061 13.3 11.8 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 EEB05438.1 - 0.17 11.9 17.6 55 3.8 0.1 7.1 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 EEB05438.1 - 0.79 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Erg28 PF03694.8 EEB05439.1 - 1.1e-38 131.6 1.3 1.3e-38 131.3 0.9 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.11 EEB05439.1 - 0.018 14.8 0.7 0.031 14.1 0.5 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange EOS1 PF12326.3 EEB05439.1 - 0.044 13.4 0.3 0.072 12.7 0.1 1.7 1 1 0 1 1 1 0 N-glycosylation protein PspA_IM30 PF04012.7 EEB05440.1 - 0.0014 17.9 1.8 0.0019 17.6 1.3 1.1 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.6 EEB05440.1 - 0.0025 16.5 2.0 0.003 16.2 1.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.6 EEB05440.1 - 0.004 17.0 1.8 0.0044 16.8 1.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) THOC7 PF05615.8 EEB05440.1 - 0.012 15.8 5.0 0.018 15.2 3.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Atg14 PF10186.4 EEB05440.1 - 0.016 14.2 6.2 0.022 13.6 4.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1854 PF08909.6 EEB05440.1 - 0.019 14.5 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Transposase_22 PF02994.9 EEB05440.1 - 0.047 12.1 1.9 0.055 11.9 1.3 1.1 1 0 0 1 1 1 0 L1 transposable element Lebercilin PF15619.1 EEB05440.1 - 0.05 13.0 8.0 0.067 12.5 5.6 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FliD_N PF02465.13 EEB05440.1 - 0.057 13.7 0.6 0.079 13.3 0.4 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Sec2p PF06428.6 EEB05440.1 - 0.073 12.9 4.0 0.12 12.2 2.8 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Tox-ODYAM1 PF15642.1 EEB05440.1 - 0.098 11.3 3.5 0.12 11.0 2.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus V_ATPase_I PF01496.14 EEB05440.1 - 0.11 10.2 1.5 0.11 10.3 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 EEB05440.1 - 0.13 11.0 4.6 0.17 10.6 3.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMPIT PF07851.8 EEB05440.1 - 0.16 11.0 2.7 0.2 10.6 1.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3391 PF11871.3 EEB05440.1 - 0.41 10.8 3.8 0.45 10.7 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) eIF-4B PF06273.6 EEB05440.1 - 0.43 9.2 3.7 0.62 8.7 2.5 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B TMF_DNA_bd PF12329.3 EEB05440.1 - 1.9 8.3 10.3 3.8 7.3 7.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 EEB05440.1 - 7.3 6.7 8.0 17 5.5 5.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CIAPIN1 PF05093.8 EEB05441.1 - 1.6e-30 105.1 7.2 1.6e-30 105.1 4.3 1.6 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DALR_1 PF05746.10 EEB05441.1 - 0.05 13.5 0.6 2.8 7.9 0.0 2.4 2 1 0 2 2 2 0 DALR anticodon binding domain DUF2011 PF09428.5 EEB05441.1 - 0.16 11.8 1.3 0.28 11.0 0.9 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) zf-CCCH PF00642.19 EEB05442.1 - 2.5e-09 36.6 32.0 0.015 15.0 1.3 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4454 PF14628.1 EEB05442.1 - 0.016 14.8 0.0 0.051 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4454) DNA_processg_A PF02481.10 EEB05442.1 - 0.041 12.7 0.3 3.1 6.6 0.2 2.3 1 1 1 2 2 2 0 DNA recombination-mediator protein A zf-CCCH_2 PF14608.1 EEB05442.1 - 0.074 13.0 25.7 0.092 12.7 1.2 5.5 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Opy2 PF09463.5 EEB05442.1 - 6.5 6.9 8.1 14 5.9 0.4 3.6 2 1 1 3 3 3 0 Opy2 protein Gtr1_RagA PF04670.7 EEB05443.1 - 1.3e-99 332.0 0.6 1.6e-99 331.7 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEB05443.1 - 2.6e-08 33.4 0.0 2.6e-08 33.4 0.0 1.9 3 0 0 3 3 3 1 Ras family MMR_HSR1 PF01926.18 EEB05443.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EEB05443.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EEB05443.1 - 7.6e-06 26.4 0.0 2.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EEB05443.1 - 7.2e-05 22.2 0.2 0.00014 21.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EEB05443.1 - 0.0013 17.6 0.8 0.017 14.0 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EEB05443.1 - 0.013 15.0 0.2 0.034 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEB05443.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter RNA_pol_Rpb4 PF03874.11 EEB05444.1 - 2.3e-24 85.6 0.0 2.8e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 COQ7 PF03232.8 EEB05445.1 - 6.6e-70 234.0 0.0 8.3e-70 233.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EEB05445.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Enolase_C PF00113.17 EEB05447.1 - 4.6e-148 491.9 0.0 6.5e-148 491.5 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEB05447.1 - 3.9e-58 195.0 0.6 6.9e-58 194.2 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EEB05447.1 - 4.8e-05 23.2 0.1 0.00041 20.2 0.0 2.2 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EEB05447.1 - 0.0072 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EEB05447.1 - 0.03 14.8 0.0 0.087 13.3 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Complex1_LYR PF05347.10 EEB05448.1 - 0.00012 21.7 1.9 0.00012 21.7 1.3 2.3 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEB05448.1 - 0.004 17.3 1.7 0.004 17.3 1.2 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEB05448.1 - 0.013 16.0 1.0 0.013 16.0 0.7 1.9 2 0 0 2 2 2 0 Complex1_LYR-like HAD PF12710.2 EEB05449.1 - 2.5e-09 37.5 0.0 3.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CPSase_L_D2 PF02786.12 EEB05450.2 - 1.1e-79 266.6 0.0 1.8e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EEB05450.2 - 9.5e-65 217.6 0.0 1.5e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EEB05450.2 - 2.9e-37 127.1 0.1 7.2e-37 125.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEB05450.2 - 1.6e-30 105.1 0.0 4.5e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EEB05450.2 - 2.1e-26 93.0 0.1 3.9e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EEB05450.2 - 3e-18 66.1 0.1 5.9e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEB05450.2 - 5.8e-17 61.4 0.0 2.6e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EEB05450.2 - 1.6e-14 53.2 0.8 3.6e-14 52.1 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EEB05450.2 - 2.7e-10 39.7 0.2 0.0009 18.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EEB05450.2 - 4.5e-08 32.6 0.0 8.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEB05450.2 - 9.1e-07 28.4 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EEB05450.2 - 0.00038 19.9 0.0 0.0015 18.0 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EEB05450.2 - 0.0005 20.3 0.1 2.1 8.7 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EEB05450.2 - 0.00053 19.8 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EEB05450.2 - 0.0021 17.4 0.2 2.3 7.4 0.0 2.8 3 0 0 3 3 3 2 HlyD family secretion protein Ribosomal_L5_C PF00673.16 EEB05451.1 - 8.3e-23 79.9 0.0 1.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEB05451.1 - 3.1e-20 71.7 0.1 8.3e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 GTP_EFTU PF00009.22 EEB05452.1 - 1.5e-40 138.6 0.0 2.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EEB05452.1 - 3.9e-36 122.9 0.4 8.6e-36 121.8 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EEB05452.1 - 6.2e-12 45.4 0.6 1.4e-11 44.2 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB05452.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEB05452.1 - 0.12 12.1 0.2 0.43 10.3 0.2 2.0 1 1 0 1 1 1 0 Dynamin family ArfGap PF01412.13 EEB05453.2 - 3e-34 117.2 1.3 5.1e-34 116.5 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EEB05453.2 - 2.1e-11 43.9 0.5 5.5e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 PH domain Ribosomal_S24e PF01282.14 EEB05454.1 - 8.9e-33 111.9 0.1 1.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EEB05454.1 - 0.064 12.4 1.2 0.07 12.3 0.9 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 RRXRR PF14239.1 EEB05454.1 - 0.089 12.1 4.4 0.1 12.0 3.1 1.2 1 0 0 1 1 1 0 RRXRR protein Acetyltransf_8 PF13523.1 EEB05455.1 - 9.7e-50 168.3 1.1 1.3e-49 167.9 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEB05455.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pro_isomerase PF00160.16 EEB05456.1 - 3.1e-33 115.1 0.0 5.2e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EEB05456.1 - 6.1e-17 61.0 0.1 9.9e-17 60.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05456.1 - 9.2e-13 47.9 0.1 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05456.1 - 4.4e-11 42.4 0.1 7.9e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleopor_Nup85 PF07575.8 EEB05457.1 - 1.1e-97 327.6 9.1 1.2e-97 327.4 6.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin DUF384 PF04064.8 EEB05458.2 - 0.087 12.3 0.1 0.84 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF384) dsrm PF00035.20 EEB05459.1 - 1.1e-07 32.3 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.9 EEB05459.1 - 0.0081 15.9 0.1 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain RRM_1 PF00076.17 EEB05460.1 - 3.3e-47 157.9 0.0 4.2e-16 58.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05460.1 - 9.2e-26 89.6 0.0 9.5e-08 31.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05460.1 - 4.4e-24 84.0 0.3 8.7e-11 41.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEB05460.1 - 0.0001 22.0 0.0 0.00082 19.1 0.0 2.5 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.1 EEB05460.1 - 0.015 15.0 0.1 0.15 11.8 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SNF2_N PF00176.18 EEB05461.2 - 3.7e-69 232.7 0.5 5.8e-69 232.1 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB05461.2 - 8.8e-14 51.1 0.0 2.3e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEB05461.2 - 2.2e-07 30.7 4.0 6.8e-07 29.2 2.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB05461.2 - 1.6e-06 27.6 4.2 2.1e-05 24.0 3.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB05461.2 - 8e-05 22.3 6.6 0.00048 19.9 4.8 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB05461.2 - 9.2e-05 22.0 4.1 0.00018 21.1 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EEB05461.2 - 0.00051 19.5 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EEB05461.2 - 0.00077 19.1 3.5 0.0012 18.5 0.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEB05461.2 - 0.0059 16.3 5.5 0.018 14.7 3.8 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EEB05461.2 - 0.036 13.5 0.8 0.13 11.7 0.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EEB05461.2 - 0.11 12.3 7.0 0.061 13.2 1.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CN_hydrolase PF00795.17 EEB05462.1 - 6.1e-16 58.3 0.0 8.4e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EEB05463.2 - 4.7e-32 110.8 2.2 3.4e-31 108.0 1.5 2.6 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EEB05463.2 - 8.1e-20 70.9 4.5 1.4e-19 70.2 0.8 3.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EEB05463.2 - 0.00062 19.6 1.7 7.8 6.8 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EEB05463.2 - 0.0074 16.7 0.0 20 5.8 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat Peptidase_M24 PF00557.19 EEB05464.1 - 1.4e-12 47.6 0.1 1.9e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DHBP_synthase PF00926.14 EEB05465.1 - 1.7e-82 275.3 0.1 1.9e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Aldedh PF00171.17 EEB05467.1 - 2.7e-125 418.3 0.0 3.3e-125 418.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Spt4 PF06093.8 EEB05468.1 - 4.6e-23 80.8 0.0 5.8e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF4448 PF14610.1 EEB05469.1 - 1.1e-26 93.4 0.2 1.3e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) YibE_F PF07907.6 EEB05469.1 - 0.034 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 YibE/F-like protein Alpha-amylase PF00128.19 EEB05470.1 - 4.8e-62 210.1 0.3 6.3e-62 209.7 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EEB05470.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_70 PF02324.11 EEB05470.1 - 0.061 11.0 0.0 0.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Pkinase PF00069.20 EEB05471.1 - 2.5e-37 128.4 0.0 2.9e-18 65.9 0.0 3.1 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05471.1 - 4.7e-12 45.5 0.0 2.6e-09 36.5 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEB05471.1 - 0.00013 21.8 0.2 0.0054 16.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEB05471.1 - 0.13 11.1 0.1 0.37 9.7 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase SBDS PF01172.13 EEB05472.1 - 9.6e-17 60.5 0.0 1.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_2 PF00152.15 EEB05473.1 - 8.9e-89 297.5 0.0 1.4e-88 296.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEB05473.1 - 7.2e-11 41.7 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEB05473.1 - 1.2e-06 27.9 0.0 0.0089 15.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EEB05473.1 - 0.013 15.1 0.2 2 7.9 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) EGL-1 PF11430.3 EEB05473.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.3 3 0 0 3 3 3 0 Programmed cell death activator EGL-1 DUF2956 PF11169.3 EEB05473.1 - 1.6 8.7 12.0 0.064 13.2 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF953 PF06110.6 EEB05474.1 - 8e-14 51.1 0.0 9.9e-14 50.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) TUG-UBL1 PF11470.3 EEB05475.2 - 1.1e-15 57.2 0.6 6e-15 54.9 0.0 2.5 3 0 0 3 3 3 1 GLUT4 regulating protein TUG UBX PF00789.15 EEB05475.2 - 0.00017 21.6 0.2 0.0013 18.7 0.0 2.6 2 1 0 2 2 2 1 UBX domain ubiquitin PF00240.18 EEB05475.2 - 0.056 12.8 0.1 3 7.2 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin family PAT1 PF09770.4 EEB05475.2 - 0.57 8.3 11.1 0.74 7.9 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RibD_C PF01872.12 EEB05476.1 - 4.6e-28 98.2 0.0 5.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain GalP_UDP_tr_C PF02744.12 EEB05476.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain FAA_hydrolase PF01557.13 EEB05477.1 - 7.9e-50 169.3 0.0 9.2e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aminotran_3 PF00202.16 EEB05478.1 - 3.8e-103 344.9 0.0 4.5e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ABC1 PF03109.11 EEB05479.1 - 2.3e-25 88.8 0.0 4.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EEB05479.1 - 0.018 14.7 0.1 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L34 PF00468.12 EEB05480.1 - 8.1e-18 63.8 9.7 1.1e-17 63.3 6.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 zf-met PF12874.2 EEB05481.2 - 2.3e-06 27.6 0.8 4.6e-06 26.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EEB05481.2 - 1.9e-05 24.2 0.1 2.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EEB05481.2 - 0.025 13.8 0.9 0.042 13.1 0.6 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Methyltransf_23 PF13489.1 EEB05483.2 - 2.4e-14 53.3 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB05483.2 - 5.3e-14 52.4 0.0 1.8e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB05483.2 - 1.3e-12 48.0 0.0 5.6e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB05483.2 - 1.6e-12 47.6 0.0 1.8e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB05483.2 - 8.1e-11 41.7 0.0 1.1e-09 38.0 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB05483.2 - 1.9e-10 41.3 0.0 9.2e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB05483.2 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB05483.2 - 2.5e-05 23.7 0.0 4.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EEB05483.2 - 3.7e-05 23.4 0.0 0.0034 17.0 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 EEB05483.2 - 0.00014 20.9 0.0 0.014 14.4 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EEB05483.2 - 0.00017 20.6 0.1 0.00078 18.5 0.0 2.2 2 1 0 2 2 2 1 Putative methyltransferase DUF3419 PF11899.3 EEB05483.2 - 0.00089 18.0 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) TPMT PF05724.6 EEB05483.2 - 0.0017 17.8 0.0 0.0017 17.8 0.0 2.1 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EEB05483.2 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.1 EEB05483.2 - 0.096 13.5 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.18 EEB05484.1 - 1.8e-63 214.1 0.1 2.9e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB05484.1 - 9.1e-12 44.6 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EEB05484.1 - 5.7e-06 25.8 7.9 5.7e-06 25.8 5.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB05484.1 - 7.4e-05 22.6 7.4 7.4e-05 22.6 5.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB05484.1 - 0.00014 21.6 6.4 0.00014 21.6 4.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EEB05484.1 - 0.0025 17.5 2.5 0.0088 15.8 1.7 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Ribul_P_3_epim PF00834.14 EEB05485.1 - 5.5e-76 254.1 0.0 6.5e-76 253.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EEB05485.1 - 0.009 15.5 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Iso_dh PF00180.15 EEB05486.1 - 1.9e-94 316.4 0.0 3.8e-94 315.4 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S17 PF00366.15 EEB05487.1 - 5.3e-31 106.4 0.9 7.9e-31 105.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Rot1 PF10681.4 EEB05488.1 - 6.1e-79 264.2 4.6 7.3e-79 264.0 3.2 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EEB05488.1 - 0.013 16.1 0.5 0.028 15.0 0.2 1.7 1 1 1 2 2 2 0 Lipocalin-like domain RRM_1 PF00076.17 EEB05489.2 - 8.1e-25 86.2 0.3 2.4e-15 55.9 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05489.2 - 1.6e-14 53.5 0.3 7.5e-09 35.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05489.2 - 1.1e-06 28.3 0.1 2e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EEB05489.2 - 0.011 15.1 1.6 0.7 9.4 0.3 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Prefoldin PF02996.12 EEB05490.2 - 1.9e-31 108.2 1.9 1.9e-31 108.2 1.3 1.8 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EEB05490.2 - 0.0049 16.6 2.3 0.0049 16.6 1.6 2.7 1 1 2 3 3 3 1 Prefoldin subunit DUF1664 PF07889.7 EEB05490.2 - 0.019 14.7 0.8 1.4 8.6 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 EEB05490.2 - 0.037 12.5 5.6 0.054 11.9 3.9 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Syntaxin-6_N PF09177.6 EEB05490.2 - 0.16 12.3 2.2 0.67 10.4 0.2 2.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4201 PF13870.1 EEB05490.2 - 0.28 10.5 6.1 0.044 13.2 0.8 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EEB05490.2 - 0.47 10.7 2.5 7.9 6.8 0.3 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.7 EEB05490.2 - 1.6 8.0 7.2 5.5 6.2 0.9 2.1 2 0 0 2 2 2 0 PspA/IM30 family PAP2 PF01569.16 EEB05491.1 - 1.8e-11 43.8 6.4 1.8e-11 43.8 4.5 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EEB05491.1 - 6.7e-08 32.2 9.6 2.2e-07 30.6 6.7 1.9 1 1 0 1 1 1 1 PAP2 superfamily IF4E PF01652.13 EEB05492.2 - 1.4e-45 154.8 0.9 4e-45 153.3 0.6 1.7 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_PK PF05891.7 EEB05493.1 - 1.9e-87 292.1 0.0 2.1e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EEB05493.1 - 2.2e-07 30.7 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB05493.1 - 3.2e-05 24.4 0.0 5.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB05493.1 - 4.1e-05 23.8 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB05493.1 - 6.8e-05 23.2 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB05493.1 - 0.0003 21.2 0.0 0.00061 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BRAP2 PF07576.7 EEB05494.1 - 3.5e-30 103.7 0.0 8.2e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EEB05494.1 - 2.2e-18 66.1 10.4 2.2e-18 66.1 7.2 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EEB05494.1 - 4.9e-08 32.6 9.8 4.9e-08 32.6 6.8 2.3 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EEB05494.1 - 0.00015 21.8 3.4 0.00015 21.8 2.4 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEB05494.1 - 0.0002 20.9 8.5 0.0002 20.9 5.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB05494.1 - 0.00084 19.3 9.7 0.00084 19.3 6.7 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EEB05494.1 - 0.036 13.7 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.7 EEB05494.1 - 0.44 10.8 7.4 1.1 9.5 0.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EEB05494.1 - 0.58 8.7 22.2 2.7 6.5 14.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ApoO PF09769.4 EEB05494.1 - 0.83 9.3 5.0 0.72 9.5 2.2 1.8 1 1 0 1 1 1 0 Apolipoprotein O TMPIT PF07851.8 EEB05494.1 - 2.4 7.1 8.3 4.5 6.2 5.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.15 EEB05494.1 - 9.2 6.0 26.7 0.58 9.9 3.3 3.7 1 1 1 2 2 2 0 Prefoldin subunit PHD PF00628.24 EEB05495.2 - 5.9e-06 25.8 11.0 1.1e-05 25.0 7.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EEB05495.2 - 0.0012 18.8 1.7 0.0025 17.7 1.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEB05495.2 - 0.0016 18.5 3.4 0.0036 17.4 2.3 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Rab5-bind PF09311.6 EEB05495.2 - 0.017 15.0 0.3 0.038 13.8 0.1 1.6 1 1 0 1 1 1 0 Rabaptin-like protein PHD_2 PF13831.1 EEB05495.2 - 0.13 11.6 5.8 0.24 10.7 4.0 1.5 1 0 0 1 1 1 0 PHD-finger AATF-Che1 PF13339.1 EEB05495.2 - 1.2 9.3 5.8 14 5.8 4.1 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor WD40 PF00400.27 EEB05496.2 - 4.8e-60 197.4 6.1 1.3e-11 43.8 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEB05496.2 - 9.5e-09 33.9 0.1 0.032 12.3 0.0 3.6 3 2 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEB05496.2 - 0.055 11.7 0.0 0.61 8.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1989 PF09347.5 EEB05496.2 - 0.07 12.5 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1989) BSD PF03909.12 EEB05497.2 - 1.9e-26 91.5 1.1 1.9e-12 46.7 0.1 4.1 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EEB05497.2 - 1.1e-13 50.6 0.1 2.4e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2458 PF10454.4 EEB05497.2 - 0.008 16.0 0.5 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) Ribosomal_S7 PF00177.16 EEB05498.1 - 5.3e-34 116.9 3.9 7.6e-34 116.4 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3700 PF12481.3 EEB05498.1 - 0.012 14.7 0.2 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Aluminium induced protein DUF2891 PF11199.3 EEB05498.1 - 0.063 11.8 0.1 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) PH_10 PF15411.1 EEB05499.2 - 1.5e-38 131.5 0.1 3.4e-38 130.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEB05499.2 - 6.1e-26 91.4 1.4 2.3e-13 50.3 0.4 2.5 1 1 1 2 2 2 2 RhoGEF domain CDC24 PF06395.6 EEB05499.2 - 2.5e-25 88.3 0.3 5.9e-25 87.1 0.2 1.7 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EEB05499.2 - 9.2e-13 47.6 0.1 2.5e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EEB05499.2 - 0.00021 21.4 0.2 0.00059 20.0 0.1 1.8 1 0 0 1 1 1 1 PH domain V_ATPase_I PF01496.14 EEB05500.2 - 1e-287 956.0 0.0 1.2e-287 955.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Vps51 PF08700.6 EEB05500.2 - 0.039 13.8 3.2 0.96 9.3 0.8 2.9 3 0 0 3 3 3 0 Vps51/Vps67 RRM_1 PF00076.17 EEB05501.1 - 9.3e-28 95.6 0.2 1.4e-17 63.1 0.0 4.2 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05501.1 - 5.2e-23 80.8 0.1 3.9e-13 49.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05501.1 - 1.8e-19 69.3 4.8 8.7e-09 35.1 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EEB05501.1 - 0.0028 17.3 0.1 1.3 8.7 0.0 2.5 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Ycf1 PF05758.7 EEB05501.1 - 0.94 7.1 20.6 1.2 6.7 14.3 1.2 1 0 0 1 1 1 0 Ycf1 FancD2 PF14631.1 EEB05501.1 - 2.9 4.8 11.7 3.6 4.5 8.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HSP90 PF00183.13 EEB05501.1 - 6 5.1 33.7 0.76 8.0 19.5 1.9 1 1 1 2 2 2 0 Hsp90 protein CM_2 PF01817.16 EEB05503.1 - 5.8e-06 26.3 0.3 0.011 15.8 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II DUF962 PF06127.6 EEB05504.2 - 2.3e-22 78.7 1.1 9.1e-22 76.7 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Acetyltransf_1 PF00583.19 EEB05504.2 - 1.5e-14 53.8 0.0 2.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB05504.2 - 8.7e-11 41.8 0.2 1.9e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEB05504.2 - 4.4e-06 26.9 0.0 6.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEB05504.2 - 3e-05 23.9 0.1 5.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB05504.2 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB05504.2 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF382 PF04037.8 EEB05504.2 - 0.13 12.0 0.8 0.22 11.3 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF382) SH3_1 PF00018.23 EEB05505.1 - 1.3e-31 107.7 4.7 1.5e-12 46.6 0.0 5.0 4 1 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EEB05505.1 - 2.2e-31 107.2 0.0 4e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EEB05505.1 - 1.7e-30 104.2 4.6 5.6e-10 38.6 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EEB05505.1 - 7.3e-21 73.4 0.0 3.8e-05 23.1 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EEB05505.1 - 0.00017 21.5 23.8 0.00017 21.5 16.5 7.2 5 2 1 6 6 6 1 Domain of unknown function (DUF1720) DSHCT PF08148.7 EEB05505.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Mito_carr PF00153.22 EEB05506.1 - 1.1e-76 252.6 0.4 1.3e-26 92.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.16 EEB05507.1 - 3.3e-40 137.0 0.7 3.9e-40 136.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Prefoldin_2 PF01920.15 EEB05508.1 - 1.4e-21 76.2 8.9 1.6e-21 76.0 6.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.7 EEB05508.1 - 0.029 13.6 3.6 0.066 12.4 2.5 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4146 PF13652.1 EEB05508.1 - 0.047 13.5 1.3 0.054 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4146) Spc24 PF08286.6 EEB05508.1 - 0.1 12.2 6.0 1.6 8.4 0.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 EEB05508.1 - 0.12 12.2 6.1 0.27 11.0 4.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3994 PF13159.1 EEB05508.1 - 0.22 11.8 1.3 0.32 11.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF883 PF05957.8 EEB05508.1 - 0.23 11.8 1.6 12 6.4 0.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Synaptonemal_3 PF15191.1 EEB05508.1 - 0.25 11.1 3.8 0.14 11.8 0.4 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Sipho_Gp157 PF05565.6 EEB05508.1 - 0.32 10.5 5.5 1.2 8.6 1.4 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1640 PF07798.6 EEB05508.1 - 0.35 10.8 7.5 2.3 8.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) XRCC4 PF06632.7 EEB05508.1 - 0.53 9.0 8.5 0.063 12.1 2.1 1.8 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Dzip-like_N PF13815.1 EEB05508.1 - 0.56 10.0 5.9 1.2 8.9 4.1 1.6 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Bacillus_HBL PF05791.6 EEB05508.1 - 0.59 9.4 5.2 0.32 10.3 1.1 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF972 PF06156.8 EEB05508.1 - 1.3 9.3 6.0 5 7.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EEB05508.1 - 2.5 7.9 6.4 0.64 9.8 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1451 PF07295.6 EEB05508.1 - 2.7 7.7 7.9 14 5.4 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Ax_dynein_light PF10211.4 EEB05508.1 - 2.8 7.7 7.8 0.86 9.4 2.0 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain TMF_DNA_bd PF12329.3 EEB05508.1 - 3.2 7.6 10.6 0.96 9.2 3.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4164 PF13747.1 EEB05508.1 - 3.6 7.7 7.3 2.3 8.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF465 PF04325.8 EEB05508.1 - 4.3 7.1 10.6 0.24 11.1 3.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Yip1 PF04893.12 EEB05509.1 - 2.5e-12 46.6 5.6 2.5e-12 46.6 3.9 1.5 1 1 1 2 2 2 1 Yip1 domain WD40 PF00400.27 EEB05510.1 - 5.8e-12 45.0 1.5 3.6 7.6 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-CCCH PF00642.19 EEB05511.1 - 1.8e-17 62.5 21.6 2.4e-07 30.2 0.4 4.3 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEB05511.1 - 0.027 14.4 0.2 0.027 14.4 0.2 4.6 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Viral_cys_rich PF08008.7 EEB05511.1 - 0.42 10.2 4.2 4 7.0 0.7 2.4 2 1 0 2 2 2 0 Viral cysteine rich Mur_ligase_M PF08245.7 EEB05513.1 - 1e-06 28.9 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Mur ligase middle domain DUF1835 PF08874.5 EEB05513.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Prefoldin_2 PF01920.15 EEB05514.1 - 5.5e-12 45.3 1.1 4.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit PRKCSH PF07915.8 EEB05515.1 - 1.3e-09 38.7 2.8 1.6e-09 38.4 0.4 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EEB05515.1 - 1.5e-05 24.5 0.1 2.9e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein WD40 PF00400.27 EEB05516.1 - 6.9e-48 158.9 14.4 3.3e-10 39.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EEB05516.1 - 6.1e-12 44.5 0.7 6.1e-12 44.5 0.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EEB05516.1 - 1.1e-05 25.2 0.0 0.3 10.7 0.0 3.5 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A NifU_N PF01592.11 EEB05517.1 - 2.5e-51 172.9 0.0 3.1e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_60s PF00428.14 EEB05517.1 - 2.1 8.7 7.2 1.6 9.1 3.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PRK PF00485.13 EEB05518.1 - 1.8e-05 24.4 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EEB05518.1 - 5e-05 23.3 0.4 8.8e-05 22.5 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EEB05518.1 - 5.2e-05 22.9 0.0 8.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EEB05518.1 - 9.4e-05 21.5 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EEB05518.1 - 0.00014 21.5 0.1 0.00043 19.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEB05518.1 - 0.00025 21.8 0.0 0.00053 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEB05518.1 - 0.00043 19.7 0.1 0.00096 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB05518.1 - 0.0016 18.3 1.1 0.01 15.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EEB05518.1 - 0.0028 16.4 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 EEB05518.1 - 0.0029 16.5 0.0 0.087 11.6 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 EEB05518.1 - 0.0031 17.4 0.8 0.0074 16.2 0.2 2.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EEB05518.1 - 0.0036 17.7 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EEB05518.1 - 0.0039 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EEB05518.1 - 0.0069 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EEB05518.1 - 0.0077 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EEB05518.1 - 0.0084 15.7 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEB05518.1 - 0.0089 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EEB05518.1 - 0.0095 16.0 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EEB05518.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EEB05518.1 - 0.01 16.1 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEB05518.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEB05518.1 - 0.016 14.6 0.1 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EEB05518.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.4 EEB05518.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 EEB05518.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EEB05518.1 - 0.027 13.9 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 EEB05518.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GTP_EFTU PF00009.22 EEB05518.1 - 0.041 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain KaiC PF06745.8 EEB05518.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.9 EEB05518.1 - 0.071 12.0 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.10 EEB05518.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 1 0 NTPase DUF87 PF01935.12 EEB05518.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 EEB05518.1 - 0.091 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EEB05518.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EEB05518.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 EEB05518.1 - 0.12 11.7 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase TrwB_AAD_bind PF10412.4 EEB05518.1 - 0.15 10.6 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF1752 PF08550.5 EEB05519.1 - 1.2e-09 37.5 2.6 2.5e-09 36.5 1.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ROS_MUCR PF05443.6 EEB05520.1 - 0.017 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein SLY PF12485.3 EEB05520.1 - 0.048 13.8 0.5 0.081 13.1 0.0 1.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Sld5 PF05916.6 EEB05521.1 - 1.7e-13 50.7 0.0 2.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L7Ae PF01248.21 EEB05522.2 - 3.5e-23 80.9 0.6 5.5e-23 80.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEB05522.2 - 0.00087 19.1 0.2 0.0012 18.6 0.2 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 Pam17 PF08566.5 EEB05522.2 - 0.079 12.6 0.1 0.4 10.3 0.0 2.0 1 1 0 2 2 2 0 Mitochondrial import protein Pam17 zf-HIT PF04438.11 EEB05523.1 - 2.8e-09 36.4 7.3 4.7e-09 35.7 5.1 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.8 EEB05523.1 - 0.091 10.4 1.0 0.08 10.5 0.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.13 EEB05523.1 - 0.37 10.7 8.2 0.81 9.6 5.7 1.7 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 EEB05524.1 - 1.6e-15 56.2 0.1 5.8e-05 22.8 0.0 4.5 4 1 0 4 4 4 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEB05524.1 - 4.5e-05 22.4 0.0 7.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.1 EEB05524.1 - 0.008 15.6 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain RRM_1 PF00076.17 EEB05525.1 - 2.5e-14 52.6 0.1 3.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05525.1 - 1.9e-09 37.3 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05525.1 - 2.9e-09 36.6 0.1 6.1e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_ToxA PF11584.3 EEB05525.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA RRM_3 PF08777.6 EEB05525.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 RNA binding motif Elongin_A PF06881.6 EEB05526.1 - 4.4e-25 88.1 0.4 6.6e-25 87.6 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ABC_tran PF00005.22 EEB05527.2 - 2.2e-46 157.5 0.6 1.1e-22 80.8 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EEB05527.2 - 7.2e-23 80.2 8.2 7.2e-23 80.2 5.7 3.8 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.1 EEB05527.2 - 1.3e-13 51.5 11.8 0.00085 19.3 0.0 5.5 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 EEB05527.2 - 2.5e-10 39.9 0.4 0.041 13.1 0.3 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEB05527.2 - 9.2e-10 39.3 3.4 0.00017 22.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 EEB05527.2 - 6e-08 32.1 0.1 0.0041 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEB05527.2 - 6e-08 32.8 0.0 0.0033 17.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EEB05527.2 - 2.4e-07 30.5 1.2 0.032 13.9 0.0 3.6 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EEB05527.2 - 3.6e-07 29.2 0.2 0.022 13.5 0.0 2.9 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EEB05527.2 - 4.2e-07 30.1 1.1 0.022 14.7 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EEB05527.2 - 7.8e-07 29.0 0.0 0.0036 17.2 0.0 3.4 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_30 PF13604.1 EEB05527.2 - 1.3e-06 28.1 0.0 0.0035 16.9 0.0 3.9 4 2 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EEB05527.2 - 1.4e-06 27.9 0.0 0.89 8.9 0.1 3.7 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EEB05527.2 - 3.1e-06 27.6 0.0 0.081 13.4 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_14 PF13173.1 EEB05527.2 - 4.3e-06 26.6 0.1 0.19 11.6 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_18 PF13238.1 EEB05527.2 - 1.4e-05 25.3 7.5 0.0051 17.1 0.0 3.9 5 1 0 5 5 2 2 AAA domain DUF258 PF03193.11 EEB05527.2 - 1.5e-05 24.2 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EEB05527.2 - 3.4e-05 24.0 0.0 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EEB05527.2 - 8.3e-05 22.4 0.5 0.2 11.6 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EEB05527.2 - 0.00012 21.8 0.1 0.57 9.8 0.0 2.9 3 0 0 3 3 2 2 NTPase RNA_helicase PF00910.17 EEB05527.2 - 0.00023 21.3 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EEB05527.2 - 0.00025 20.9 0.0 0.23 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEB05527.2 - 0.00032 20.7 3.5 0.086 12.8 0.3 3.5 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EEB05527.2 - 0.001 18.7 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 EEB05527.2 - 0.0013 18.1 0.6 2.6 7.4 0.3 3.5 3 1 0 3 3 2 1 AAA domain KAP_NTPase PF07693.9 EEB05527.2 - 0.0021 17.1 0.3 1.9 7.3 0.0 3.5 3 1 0 3 3 3 1 KAP family P-loop domain AAA_5 PF07728.9 EEB05527.2 - 0.0037 16.9 0.1 3.9 7.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) cobW PF02492.14 EEB05527.2 - 0.015 14.7 0.2 4.7 6.6 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EEB05527.2 - 0.015 15.6 28.9 0.49 10.6 0.0 5.3 5 1 0 5 5 4 0 AAA domain ATP-synt_ab PF00006.20 EEB05527.2 - 0.018 14.5 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EEB05527.2 - 0.021 13.7 0.0 0.49 9.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EEB05527.2 - 0.032 13.7 3.1 1.9 7.9 0.0 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEB05527.2 - 0.032 14.0 10.9 0.07 12.9 0.0 3.5 4 2 0 4 4 2 0 Dynamin family DUF87 PF01935.12 EEB05527.2 - 0.082 12.7 15.6 0.12 12.1 0.0 4.7 4 1 1 5 5 5 0 Domain of unknown function DUF87 DAP3 PF10236.4 EEB05527.2 - 0.23 10.3 4.0 1.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FlxA PF14282.1 EEB05527.2 - 1.8 8.5 8.3 0.16 11.8 2.1 2.0 2 0 0 2 2 1 0 FlxA-like protein ATP_sub_h PF10775.4 EEB05528.1 - 6.8e-12 44.9 0.2 1.1e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EEB05528.1 - 0.02 14.8 0.1 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Mito_carr PF00153.22 EEB05529.1 - 2.7e-40 135.9 1.9 1.4e-15 56.7 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S4 PF00163.14 EEB05530.1 - 2.4e-29 101.5 1.8 4.8e-29 100.5 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEB05530.1 - 1.9e-12 46.4 1.6 1.9e-12 46.4 1.1 2.3 3 0 0 3 3 3 1 S4 domain PWWP PF00855.12 EEB05531.2 - 7.1e-17 61.3 0.2 6.4e-16 58.3 0.0 2.6 2 0 0 2 2 2 1 PWWP domain UCH PF00443.24 EEB05532.1 - 5.8e-65 219.0 1.2 7.9e-65 218.6 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB05532.1 - 4.9e-34 118.1 0.3 1.1e-31 110.3 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EEB05532.1 - 0.0032 16.8 0.7 3 7.0 0.2 3.0 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CortBP2 PF09727.4 EEB05532.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Cofilin_ADF PF00241.15 EEB05532.1 - 0.09 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EEB05533.2 - 4.2e-39 132.1 10.9 9.2e-16 57.3 0.2 3.9 3 1 1 4 4 4 4 Mitochondrial carrier protein Topoisom_I_N PF02919.10 EEB05534.2 - 1.2e-101 338.5 2.4 1.2e-101 338.5 1.7 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EEB05534.2 - 2.2e-71 239.6 0.1 2.2e-71 239.6 0.1 3.1 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EEB05534.2 - 5.7e-29 99.5 1.0 5.7e-29 99.5 0.7 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain Sec1 PF00995.18 EEB05535.1 - 1.2e-86 291.5 0.0 1.4e-86 291.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.27 EEB05536.1 - 3.6e-13 48.8 7.0 4e-07 29.6 1.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EEB05536.1 - 1e-06 28.6 0.0 3.7e-06 26.7 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RhoGAP PF00620.22 EEB05537.1 - 1.1e-35 122.5 0.6 4.4e-35 120.5 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EEB05537.1 - 4.5e-21 74.6 44.1 2.3e-12 46.7 4.8 4.7 4 0 0 4 4 4 3 LIM domain Rad50_zn_hook PF04423.9 EEB05537.1 - 0.011 15.1 0.8 0.3 10.5 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif RNase_H2_suC PF08615.6 EEB05537.1 - 0.066 13.0 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-RING_2 PF13639.1 EEB05538.1 - 2.7e-21 75.1 14.2 6e-16 57.9 2.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 EEB05538.1 - 2.8e-10 40.0 10.3 1.3e-07 31.5 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEB05538.1 - 5.5e-10 39.2 9.7 1.3e-09 38.0 1.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEB05538.1 - 6.9e-10 38.4 12.1 2.4e-08 33.4 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB05538.1 - 2.2e-09 36.8 12.2 1.1e-06 28.3 1.5 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EEB05538.1 - 3.1e-07 29.9 11.4 5.8e-06 25.8 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB05538.1 - 1.3e-06 27.9 3.3 0.00014 21.5 0.1 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-Apc11 PF12861.2 EEB05538.1 - 0.00011 21.9 5.5 0.00013 21.6 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EEB05538.1 - 0.032 14.1 8.4 0.72 9.7 1.5 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEB05538.1 - 0.057 13.3 8.8 0.14 12.1 1.9 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEB05538.1 - 0.12 11.9 15.2 0.04 13.5 3.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EEB05538.1 - 1.7 8.7 7.5 2.4 8.2 1.4 2.5 2 1 0 2 2 2 0 RING-variant domain DUF846 PF05832.7 EEB05539.1 - 1.5e-49 167.3 10.8 1.8e-49 167.1 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) MDM31_MDM32 PF08118.6 EEB05539.1 - 0.051 12.0 0.1 0.072 11.5 0.1 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins RseC_MucC PF04246.7 EEB05539.1 - 9.9 5.7 7.0 6.3 6.3 0.1 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Prenyltransf PF01255.14 EEB05540.1 - 6.7e-09 35.2 0.0 6.3e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase zf-PARP PF00645.13 EEB05541.2 - 3.1e-20 72.1 0.0 5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Met_gamma_lyase PF06838.6 EEB05541.2 - 0.076 11.3 0.1 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DTHCT PF08070.6 EEB05541.2 - 1 10.0 7.2 3.3 8.4 5.0 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region Longin PF13774.1 EEB05543.1 - 1.3e-28 98.3 0.1 2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEB05543.1 - 3e-15 55.5 0.0 4.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Phosducin PF02114.11 EEB05544.1 - 4.9e-24 84.4 0.2 6e-24 84.1 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EEB05544.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Bin3 PF06859.7 EEB05545.2 - 5.5e-21 74.6 0.0 9.1e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.1 EEB05545.2 - 1.9e-13 50.2 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEB05545.2 - 2.1e-12 47.0 0.0 2.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB05545.2 - 4.5e-12 46.5 0.0 9.1e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB05545.2 - 4.4e-09 36.7 0.0 0.00077 19.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EEB05545.2 - 1.7e-08 34.4 0.0 4.1e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB05545.2 - 2.8e-08 34.1 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB05545.2 - 9.2e-08 32.3 0.0 1.6e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEB05545.2 - 5.6e-05 22.4 0.0 0.00017 20.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EEB05545.2 - 0.00039 19.5 0.0 0.39 9.7 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase MTS PF05175.9 EEB05545.2 - 0.0014 17.9 0.0 0.043 13.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EEB05545.2 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EEB05545.2 - 0.0059 15.6 0.0 0.022 13.7 0.0 1.8 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EEB05545.2 - 0.0061 15.2 0.0 0.083 11.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EEB05545.2 - 0.038 13.0 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EEB05545.2 - 0.05 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EEB05545.2 - 0.055 12.8 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) SAC3_GANP PF03399.11 EEB05546.1 - 1.3e-67 227.3 4.5 1.7e-67 226.9 3.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEB05546.1 - 5.1e-08 32.7 0.8 5.1e-08 32.7 0.6 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 COX5A PF02284.11 EEB05546.1 - 0.034 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DUF2361 PF10153.4 EEB05548.1 - 1.7e-31 108.7 15.4 1.7e-31 108.7 10.7 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) ING PF12998.2 EEB05548.1 - 0.0036 17.5 2.0 0.0036 17.5 1.4 2.3 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Arch_fla_DE PF04659.8 EEB05548.1 - 0.065 13.0 1.3 0.14 11.9 0.0 2.1 2 1 1 3 3 3 0 Archaeal flagella protein RbsD_FucU PF05025.8 EEB05548.1 - 3.5 7.9 5.5 1.2 9.4 0.7 2.0 1 1 1 2 2 2 0 RbsD / FucU transport protein family RRM_6 PF14259.1 EEB05549.2 - 9.7e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB05549.2 - 2.6e-07 30.1 0.0 6.4e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05549.2 - 2.7e-07 30.3 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EEB05550.2 - 6.1e-118 394.5 6.5 6.9e-118 394.3 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop10p PF04135.7 EEB05551.1 - 3.2e-23 81.1 1.0 3.9e-23 80.9 0.7 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Hid1 PF12722.2 EEB05552.1 - 1e-172 576.0 25.3 3.1e-172 574.5 17.5 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEB05552.1 - 3.3e-36 124.6 8.0 1.3e-35 122.7 5.5 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TOM13 PF08219.6 EEB05553.1 - 5.3e-12 45.3 0.1 5.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Metallophos PF00149.23 EEB05554.1 - 2.1e-06 27.3 3.8 4.4e-06 26.2 2.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NST1 PF13945.1 EEB05554.1 - 0.086 12.9 8.0 0.71 9.9 1.8 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator SRP72 PF08492.7 EEB05554.1 - 0.18 12.2 9.9 4.3 7.7 0.1 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain BLVR PF06375.6 EEB05554.1 - 1.4 8.7 10.0 7.8 6.3 0.5 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) WD40 PF00400.27 EEB05555.1 - 1.6e-32 110.2 17.4 3.2e-11 42.6 0.2 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEB05555.1 - 0.00018 21.2 0.2 0.34 10.6 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EEB05555.1 - 0.00045 19.9 0.2 0.84 9.3 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EEB05555.1 - 0.0029 16.4 0.2 0.25 10.0 0.1 2.3 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 EEB05555.1 - 0.022 14.2 0.2 0.49 9.8 0.1 2.5 1 1 1 2 2 2 0 PQQ-like domain WD40 PF00400.27 EEB05556.1 - 9.7e-53 174.2 21.3 2e-11 43.2 0.1 12.7 14 0 0 14 14 14 9 WD domain, G-beta repeat Utp12 PF04003.7 EEB05556.1 - 2.3e-22 78.9 0.1 3.6e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EEB05556.1 - 4.8e-05 21.6 5.9 0.05 11.7 0.1 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EEB05556.1 - 0.00015 20.9 0.6 1.7 7.6 0.1 4.0 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 EEB05556.1 - 0.0054 15.5 0.0 1.9 7.1 0.0 3.3 3 1 1 4 4 4 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 EEB05556.1 - 0.021 13.1 0.2 0.49 8.6 0.0 2.9 4 1 1 5 5 5 0 Cytochrome D1 heme domain IKI3 PF04762.7 EEB05556.1 - 0.056 11.2 0.1 0.82 7.4 0.0 2.8 3 1 1 4 4 4 0 IKI3 family UCH PF00443.24 EEB05557.1 - 1.7e-58 197.8 0.7 1.7e-58 197.8 0.5 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EEB05557.1 - 8.8e-57 192.1 14.9 7e-56 189.2 8.7 2.5 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EEB05557.1 - 1.7e-54 184.4 16.2 4.7e-54 183.0 0.3 3.2 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EEB05557.1 - 5e-32 111.5 0.0 9.7e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EEB05557.1 - 1.2e-06 28.8 0.2 0.00017 21.8 0.0 3.4 2 1 0 2 2 2 1 MATH domain NDUF_B5 PF09781.4 EEB05557.1 - 0.014 14.6 0.9 2.6 7.2 0.1 2.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit ubiquitin PF00240.18 EEB05557.1 - 0.026 13.9 0.0 3.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin family Astro_capsid PF03115.9 EEB05557.1 - 2.6 6.1 4.5 3.9 5.6 3.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SGS PF05002.10 EEB05558.2 - 1.4e-31 108.0 1.2 1.4e-31 108.0 0.8 2.3 3 0 0 3 3 3 1 SGS domain CS PF04969.11 EEB05558.2 - 1.3e-15 57.7 0.1 4.1e-15 56.0 0.1 1.9 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EEB05558.2 - 0.00023 20.7 2.1 0.0011 18.5 0.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.1 EEB05558.2 - 0.025 14.4 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05558.2 - 0.099 13.3 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2057 PF09829.4 EEB05558.2 - 0.58 9.7 7.9 0.06 13.0 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Rifin_STEVOR PF02009.11 EEB05559.1 - 0.0037 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Adeno_E3_CR2 PF02439.10 EEB05559.1 - 0.0045 16.4 2.7 0.0089 15.5 1.8 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.1 EEB05559.1 - 6.7 6.8 9.6 0.44 10.6 0.2 2.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PRELI PF04707.9 EEB05560.1 - 2.6e-48 163.5 1.4 3.1e-48 163.3 1.0 1.0 1 0 0 1 1 1 1 PRELI-like family IL7 PF01415.11 EEB05560.1 - 0.12 12.0 0.5 0.19 11.3 0.4 1.4 1 1 0 1 1 1 0 Interleukin 7/9 family DUF3449 PF11931.3 EEB05561.1 - 4.5e-65 218.8 0.5 4.5e-65 218.8 0.3 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EEB05561.1 - 6.7e-10 38.3 2.5 8.6e-10 37.9 0.3 2.4 3 0 0 3 3 3 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EEB05561.1 - 1.9e-08 34.1 9.0 2.8e-08 33.6 2.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB05561.1 - 5.2e-08 32.8 3.3 2.3e-06 27.6 1.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEB05561.1 - 0.00013 22.0 4.2 0.0011 19.0 2.1 2.7 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EEB05561.1 - 0.05 13.1 0.8 0.05 13.1 0.5 2.4 3 0 0 3 3 3 0 U1 zinc finger zf-Di19 PF05605.7 EEB05561.1 - 0.25 11.4 2.6 0.45 10.6 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.7 EEB05561.1 - 0.28 10.9 6.6 0.25 11.0 0.2 3.6 4 0 0 4 4 4 0 DBF zinc finger zf-C2H2 PF00096.21 EEB05561.1 - 0.32 11.4 6.0 0.72 10.3 0.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB05561.1 - 6.9 7.2 5.8 34 5.0 0.5 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger COG2 PF06148.6 EEB05562.1 - 4.6e-13 49.1 7.5 7e-13 48.5 5.2 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EEB05562.1 - 1.2e-06 28.2 0.4 1.2e-06 28.2 0.3 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EEB05562.1 - 0.0023 16.4 4.4 0.0028 16.1 3.0 1.2 1 0 0 1 1 1 1 Dor1-like family Prominin PF05478.6 EEB05562.1 - 0.0059 14.2 3.7 0.0067 14.0 2.6 1.1 1 0 0 1 1 1 1 Prominin Spc7 PF08317.6 EEB05562.1 - 0.01 14.5 7.8 0.013 14.1 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EEB05562.1 - 0.033 12.0 2.9 0.036 11.9 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRS4 PF10422.4 EEB05562.1 - 0.039 13.2 5.8 0.031 13.6 2.2 1.7 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 DUF342 PF03961.8 EEB05562.1 - 0.061 11.7 3.4 0.07 11.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 EEB05562.1 - 0.11 12.4 4.2 0.16 11.8 2.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GCOM2 PF15328.1 EEB05562.1 - 0.11 12.2 6.1 0.16 11.7 4.2 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF948 PF06103.6 EEB05562.1 - 0.22 11.4 3.5 0.52 10.2 2.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3510 PF12022.3 EEB05562.1 - 0.23 11.5 3.9 0.19 11.8 1.7 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3510) Plasmid_killer PF05015.8 EEB05562.1 - 0.28 11.3 2.5 3.2 7.9 0.9 2.5 1 1 1 2 2 2 0 Plasmid maintenance system killer protein Laminin_II PF06009.7 EEB05562.1 - 0.31 10.8 5.1 0.58 9.9 2.9 1.8 1 1 0 1 1 1 0 Laminin Domain II Lge1 PF11488.3 EEB05562.1 - 0.44 10.7 8.4 0.87 9.8 4.6 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 BRE1 PF08647.6 EEB05562.1 - 0.51 10.3 10.8 1.4 8.8 7.5 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase TetR_C_2 PF08361.6 EEB05562.1 - 0.78 9.6 4.6 1.4 8.8 0.5 2.4 1 1 1 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Exonuc_VII_L PF02601.10 EEB05562.1 - 0.92 8.6 5.0 0.94 8.5 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0449 PF15136.1 EEB05562.1 - 1.9 8.7 5.7 14 5.9 0.0 2.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Adeno_PIX PF03955.9 EEB05562.1 - 3.3 8.2 6.1 0.76 10.3 0.4 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 EEB05562.1 - 5.4 6.5 15.9 12 5.4 11.0 1.4 1 1 0 1 1 1 0 IncA protein IKI3 PF04762.7 EEB05563.1 - 2.7e-287 955.4 0.0 3.5e-287 955.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 EEB05563.1 - 0.0051 16.5 0.1 6 6.5 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.15 EEB05563.1 - 0.01 15.4 6.8 0.11 12.0 0.1 3.5 2 1 1 3 3 3 0 Region in Clathrin and VPS polyprenyl_synt PF00348.12 EEB05564.1 - 1.9e-56 190.8 0.0 2.3e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Hist_deacetyl PF00850.14 EEB05565.1 - 2.1e-83 280.1 0.1 2.9e-83 279.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.5 EEB05565.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NIL domain PALP PF00291.20 EEB05566.1 - 1.6e-64 218.1 0.1 1.9e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.24 EEB05567.1 - 1.3e-40 138.7 0.3 2.3e-40 137.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB05567.1 - 9.5e-23 79.8 0.0 2.3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEB05567.1 - 1.1e-20 72.9 0.1 2.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEB05567.1 - 5.1e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIID_30kDa PF03540.8 EEB05568.1 - 1.4e-23 82.4 0.1 2e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EEB05568.1 - 0.15 11.8 0.1 6.6 6.5 0.0 2.4 3 0 0 3 3 3 0 Bromodomain associated Menin PF05053.8 EEB05568.1 - 1.4 6.9 4.3 2 6.5 3.0 1.1 1 0 0 1 1 1 0 Menin WD40 PF00400.27 EEB05569.1 - 2.6e-05 23.9 5.9 1.4 8.8 0.0 6.3 6 1 0 6 6 6 1 WD domain, G-beta repeat DUF4551 PF15087.1 EEB05569.1 - 0.18 10.0 1.7 0.24 9.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF775 PF05603.7 EEB05570.1 - 5.5e-59 199.0 0.1 7.5e-59 198.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RTA1 PF04479.8 EEB05571.1 - 1.1e-58 198.3 3.7 1.6e-58 197.8 2.6 1.1 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 EEB05572.1 - 2e-36 125.6 2.4 6.3e-18 65.0 0.2 2.2 1 1 1 2 2 2 2 RTA1 like protein DUF3309 PF11752.3 EEB05572.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) PepSY_TM_3 PF13706.1 EEB05572.1 - 0.2 11.1 2.0 0.49 9.8 1.4 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix DUF2484 PF10658.4 EEB05572.1 - 0.96 9.6 6.6 1.5 9.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) DUF3437 PF11919.3 EEB05573.1 - 1.4e-08 34.3 0.0 7.5e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 EEB05573.1 - 2.8e-07 30.6 0.6 2.4 8.4 0.1 5.7 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEB05573.1 - 0.018 15.5 1.6 27 5.4 0.1 5.4 5 0 0 5 5 5 0 HEAT-like repeat z-alpha PF02295.12 EEB05573.1 - 0.021 14.5 0.1 0.99 9.2 0.1 3.0 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain Arm PF00514.18 EEB05573.1 - 0.2 11.5 3.4 0.91 9.4 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EEB05573.1 - 4.6 7.5 8.2 3.1 8.1 0.1 5.0 6 0 0 6 6 6 0 HEAT repeat IGPD PF00475.13 EEB05574.1 - 5e-59 198.3 0.2 6.3e-59 197.9 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase rve PF00665.21 EEB05574.1 - 0.12 12.5 0.0 25 5.0 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain adh_short PF00106.20 EEB05575.2 - 6.2e-22 78.2 6.3 1e-16 61.2 0.2 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEB05575.2 - 2.1e-11 44.0 0.4 3.4e-11 43.3 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB05575.2 - 2e-09 37.3 7.0 1.5e-07 31.2 4.9 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEB05575.2 - 2.9e-09 36.7 0.6 5.1e-08 32.6 0.4 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEB05575.2 - 3.4e-05 22.8 0.7 0.027 13.3 0.0 2.4 1 1 1 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEB05575.2 - 4.4e-05 22.5 0.4 0.0084 15.0 0.1 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EEB05575.2 - 0.0014 17.4 0.9 0.06 12.0 0.6 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEB05575.2 - 0.014 14.6 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EEB05575.2 - 0.024 13.5 1.0 0.12 11.2 0.7 2.2 1 1 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 EEB05575.2 - 0.045 13.7 4.3 3.7 7.5 3.0 2.8 1 1 0 1 1 1 0 NADH(P)-binding ELFV_dehydrog PF00208.16 EEB05575.2 - 0.05 13.1 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2433 PF10360.4 EEB05577.1 - 1.4e-34 119.2 0.1 5.7e-34 117.2 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EEB05577.1 - 0.00024 20.5 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2112 PF09885.4 EEB05577.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) TFIIA PF03153.8 EEB05577.1 - 5.8 6.7 20.4 11 5.8 14.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRMT5 PF05185.11 EEB05578.1 - 6.8e-158 526.2 0.0 8.3e-158 525.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EEB05579.1 - 2.8e-25 88.3 0.0 6.4e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEB05579.1 - 5e-25 87.4 0.0 9.9e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEB05579.1 - 1.4e-12 47.2 0.0 3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB05579.1 - 2.5e-07 30.3 0.2 7.3e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB05579.1 - 0.00013 22.0 0.2 0.00056 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EEB05579.1 - 0.005 16.7 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EEB05579.1 - 0.0088 15.9 0.8 4.3 7.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.17 EEB05579.1 - 0.016 14.6 0.2 0.093 12.1 0.1 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EEB05579.1 - 0.016 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EEB05579.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.1 EEB05579.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEB05579.1 - 0.12 11.6 0.1 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Glyco_transf_15 PF01793.11 EEB05580.1 - 2.8e-127 424.2 6.8 3.5e-127 423.9 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ABC_tran PF00005.22 EEB05581.1 - 2.4e-46 157.4 0.0 2.3e-23 83.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EEB05581.1 - 2.1e-18 65.9 3.7 2.1e-18 65.9 2.6 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EEB05581.1 - 2.2e-17 63.9 5.2 0.00044 20.3 0.1 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EEB05581.1 - 3.4e-09 36.0 0.3 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EEB05581.1 - 5.1e-09 35.6 2.4 0.63 9.2 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEB05581.1 - 2.3e-08 34.6 8.4 0.0054 17.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EEB05581.1 - 1e-07 32.7 1.6 0.0037 18.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEB05581.1 - 6.2e-07 29.0 0.1 0.0082 15.6 0.0 2.7 2 1 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EEB05581.1 - 1.7e-06 28.0 0.0 0.0028 17.5 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEB05581.1 - 2.6e-06 27.5 0.5 0.11 12.6 0.0 3.6 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEB05581.1 - 2.8e-06 26.6 0.0 0.0044 16.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EEB05581.1 - 3.1e-06 27.6 0.1 0.1 13.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_18 PF13238.1 EEB05581.1 - 1.1e-05 25.6 1.3 0.25 11.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EEB05581.1 - 2.1e-05 24.1 2.7 0.17 11.2 0.1 3.7 3 1 0 3 3 3 2 AAA-like domain AAA_28 PF13521.1 EEB05581.1 - 2.4e-05 24.3 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEB05581.1 - 2.5e-05 24.0 0.1 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 EEB05581.1 - 5.6e-05 22.6 0.0 0.15 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEB05581.1 - 5.8e-05 23.1 2.8 0.066 13.2 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.1 EEB05581.1 - 6.6e-05 22.1 5.9 0.15 11.0 0.0 4.5 3 1 1 5 5 5 1 AAA ATPase domain RNA_helicase PF00910.17 EEB05581.1 - 0.00018 21.6 0.6 1.7 8.8 0.0 3.6 4 0 0 4 4 4 2 RNA helicase AAA_33 PF13671.1 EEB05581.1 - 0.00021 21.1 0.3 0.2 11.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EEB05581.1 - 0.00028 20.7 8.6 0.14 11.9 0.1 4.0 2 1 1 3 3 3 2 Dynamin family AAA_14 PF13173.1 EEB05581.1 - 0.00029 20.7 0.2 2.3 8.1 0.0 4.0 3 1 0 4 4 4 1 AAA domain MobB PF03205.9 EEB05581.1 - 0.00035 20.2 0.1 0.16 11.6 0.1 3.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EEB05581.1 - 0.00067 19.5 3.6 0.28 10.9 0.0 3.6 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA PF00004.24 EEB05581.1 - 0.00091 19.4 0.3 3.2 7.9 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EEB05581.1 - 0.0015 18.3 0.3 0.83 9.6 0.0 3.3 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EEB05581.1 - 0.0051 15.6 0.0 1.5 7.4 0.0 2.7 2 0 0 2 2 2 1 ArgK protein DUF2730 PF10805.3 EEB05581.1 - 0.0073 16.0 0.1 0.025 14.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) AAA_5 PF07728.9 EEB05581.1 - 0.0087 15.7 0.7 4.8 6.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEB05581.1 - 0.0097 15.4 0.4 2.2 7.8 0.0 3.3 3 1 1 4 4 2 1 AAA domain ATP-synt_ab PF00006.20 EEB05581.1 - 0.015 14.7 0.0 0.93 8.9 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 EEB05581.1 - 0.018 14.3 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.1 EEB05581.1 - 0.021 14.4 0.5 3.4 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain T2SE PF00437.15 EEB05581.1 - 0.035 12.9 0.2 2.2 7.1 0.0 2.8 2 1 0 3 3 3 0 Type II/IV secretion system protein Septin PF00735.13 EEB05581.1 - 0.037 13.0 0.9 4.5 6.2 0.0 2.6 3 0 0 3 3 2 0 Septin PduV-EutP PF10662.4 EEB05581.1 - 0.074 12.5 0.9 10 5.6 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EEB05581.1 - 0.1 12.3 0.1 5.3 6.8 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain Mt_ATP-synt_D PF05873.7 EEB05581.1 - 1.5 8.4 7.3 1 9.0 0.1 3.0 3 1 0 3 3 2 0 ATP synthase D chain, mitochondrial (ATP5H) AAA_13 PF13166.1 EEB05581.1 - 3.7 5.8 11.7 2.2 6.6 0.0 3.8 2 1 1 3 3 3 0 AAA domain Metallophos PF00149.23 EEB05582.1 - 1.5e-41 142.0 0.7 1.9e-41 141.6 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCR_TM PF02921.9 EEB05583.1 - 5.5e-20 71.3 0.6 8.3e-20 70.7 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EEB05583.1 - 6.1e-18 64.1 0.1 1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fea1 PF07692.6 EEB05583.1 - 0.085 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein NOD PF06816.8 EEB05583.1 - 0.11 11.6 1.0 1 8.5 0.0 2.7 3 0 0 3 3 3 0 NOTCH protein DUF3807 PF12720.2 EEB05584.1 - 9.2e-28 97.5 0.0 1.1e-26 93.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3807) GEMIN8 PF15348.1 EEB05584.1 - 0.023 14.7 4.6 0.085 12.8 3.2 1.8 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Pro_isomerase PF00160.16 EEB05585.1 - 9.7e-38 129.8 0.0 1.9e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD End3 PF12761.2 EEB05585.1 - 0.0089 15.6 5.9 0.0089 15.6 4.1 1.8 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Fzo_mitofusin PF04799.8 EEB05585.1 - 0.071 12.4 1.1 0.13 11.6 0.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF342 PF03961.8 EEB05585.1 - 0.11 10.9 4.8 0.17 10.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC-167 PF15188.1 EEB05585.1 - 8.1 6.4 10.6 0.29 11.0 2.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pho88 PF10032.4 EEB05586.1 - 8.1e-54 181.7 0.1 9.7e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.16 EEB05587.1 - 7.6e-40 135.8 0.0 1.7e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EEB05587.1 - 7.4e-32 108.7 0.7 1.8e-31 107.5 0.3 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEB05587.1 - 1.9e-21 75.1 2.3 3.3e-21 74.3 1.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EEB05587.1 - 1.3e-08 34.7 1.1 7.5e-08 32.3 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EEB05587.1 - 0.001 19.2 0.2 0.0091 16.2 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEB05587.1 - 0.0067 16.5 0.3 0.027 14.5 0.0 2.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase CCDC-167 PF15188.1 EEB05587.1 - 3.6 7.5 8.2 0.19 11.7 0.5 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 EEB05587.1 - 7.2 6.1 7.1 0.34 10.4 0.8 1.9 2 0 0 2 2 2 0 Septum formation initiator PFK PF00365.15 EEB05588.1 - 2.7e-166 551.5 4.0 7.5e-121 402.4 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Sad1_UNC PF07738.8 EEB05589.2 - 6.6e-32 110.1 0.0 1.3e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1664 PF07889.7 EEB05589.2 - 0.006 16.3 4.0 0.006 16.3 2.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) HALZ PF02183.13 EEB05589.2 - 0.16 11.7 0.1 0.16 11.7 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Caudal_act PF04731.7 EEB05589.2 - 0.25 11.6 3.5 1.1 9.5 1.8 2.2 2 0 0 2 2 2 0 Caudal like protein activation region DUF904 PF06005.7 EEB05589.2 - 1.9 8.8 15.2 1.8 8.9 1.8 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EEB05589.2 - 2.5 7.2 11.0 2.7 7.0 5.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EEB05589.2 - 7 6.4 13.6 3.4 7.4 1.9 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_pol_delta_4 PF04081.8 EEB05590.1 - 1.8e-28 99.2 0.7 2.7e-28 98.7 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cpn60_TCP1 PF00118.19 EEB05591.1 - 1.7e-144 482.0 12.2 2e-144 481.8 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EEB05592.1 - 7.5e-64 215.3 0.0 5e-63 212.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05592.1 - 1.7e-37 128.8 0.0 9.3e-36 123.2 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.11 EEB05592.1 - 2.1e-23 81.8 17.5 9e-14 50.9 3.1 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EEB05592.1 - 7.9e-21 73.5 32.7 9.3e-11 41.2 9.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EEB05592.1 - 6.4e-11 42.5 0.8 1.6e-10 41.2 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB05592.1 - 2.7e-05 23.2 0.0 5.9e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Uds1 PF15456.1 EEB05592.1 - 0.021 14.8 8.5 0.067 13.1 0.8 2.7 2 0 0 2 2 2 0 Up-regulated During Septation C2 PF00168.25 EEB05592.1 - 0.072 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 C2 domain PHD PF00628.24 EEB05592.1 - 4.8 6.9 25.2 0.14 11.8 6.0 2.5 2 0 0 2 2 2 0 PHD-finger HORMA PF02301.13 EEB05593.1 - 4.6e-06 26.2 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Mito_carr PF00153.22 EEB05594.1 - 2.4e-71 235.5 1.1 1.4e-22 79.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PIN PF01850.16 EEB05594.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 PIN domain Cyclin_N PF00134.18 EEB05595.1 - 3.8e-13 49.1 0.1 5.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EEB05595.1 - 0.036 13.8 0.2 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Thioredoxin PF00085.15 EEB05596.2 - 1.2e-27 95.6 0.0 1.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEB05596.2 - 5.8e-09 36.1 0.2 2.6e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEB05596.2 - 2.6e-08 33.8 0.1 2.2e-06 27.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EEB05596.2 - 0.00021 20.8 0.3 0.04 13.4 0.1 2.1 1 1 1 2 2 2 2 Redoxin Phosducin PF02114.11 EEB05596.2 - 0.00077 18.2 0.0 0.00084 18.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 EEB05596.2 - 0.00084 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 EEB05596.2 - 0.0045 16.6 0.1 0.032 13.9 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 EEB05596.2 - 0.0051 16.3 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 EEB05596.2 - 0.0057 16.2 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 EEB05596.2 - 0.0077 16.2 0.0 0.65 9.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin HyaE PF07449.6 EEB05596.2 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EEB05596.2 - 0.015 15.2 0.4 0.031 14.2 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.19 EEB05596.2 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin DUF836 PF05768.9 EEB05596.2 - 0.05 13.8 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 EEB05596.2 - 0.16 11.5 0.3 0.49 9.9 0.0 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain ubiquitin PF00240.18 EEB05597.1 - 7.2e-26 89.3 0.1 8e-26 89.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEB05597.1 - 1e-16 60.3 0.1 1.1e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB05597.1 - 5.7e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EEB05597.1 - 0.076 13.2 0.0 0.084 13.0 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CTDII PF01556.13 EEB05597.1 - 0.11 12.4 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 DnaJ C terminal domain DEAD PF00270.24 EEB05598.2 - 6.3e-38 129.9 0.4 1.4e-37 128.7 0.3 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEB05598.2 - 4.3e-21 74.2 0.3 9.3e-21 73.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEB05598.2 - 4.2e-18 64.9 0.0 1.4e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB05598.2 - 5.5e-07 29.6 0.1 5.5e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EEB05598.2 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEB05598.2 - 0.1 12.7 1.8 1.3 9.1 0.7 2.7 2 1 0 2 2 2 0 AAA domain DUF3245 PF11595.3 EEB05599.2 - 3.6e-12 46.7 15.9 3.6e-12 46.7 11.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) Sporozoite_P67 PF05642.6 EEB05599.2 - 0.0071 14.2 3.9 0.01 13.7 2.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen G-patch_2 PF12656.2 EEB05599.2 - 0.045 13.5 0.1 0.045 13.5 0.0 2.2 2 1 0 2 2 2 0 DExH-box splicing factor binding site DUF2702 PF10863.3 EEB05599.2 - 0.13 11.9 6.4 0.056 13.1 2.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2702) DUF4611 PF15387.1 EEB05599.2 - 0.86 9.7 7.4 0.21 11.7 2.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EEB05599.2 - 3.9 7.8 11.6 0.72 10.1 5.6 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hep_59 PF07052.6 EEB05599.2 - 6.6 7.1 14.2 0.92 9.8 4.1 2.6 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 WD40 PF00400.27 EEB05600.1 - 3.5e-28 96.4 14.0 1.5e-09 37.3 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF3639 PF12341.3 EEB05600.1 - 3.8e-10 39.5 0.8 1.1e-09 38.1 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) PQQ_3 PF13570.1 EEB05600.1 - 0.00017 21.7 0.3 13 6.2 0.0 4.5 4 0 0 4 4 4 2 PQQ-like domain Coatomer_WDAD PF04053.9 EEB05600.1 - 0.0014 17.5 0.2 0.092 11.5 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 EEB05600.1 - 0.0016 16.8 1.5 0.79 7.9 0.0 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain RNA_pol_Rpc82 PF05645.8 EEB05601.2 - 7.6e-34 117.4 3.1 3.3e-32 112.0 2.1 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EEB05601.2 - 4.8e-21 74.3 3.9 2.1e-18 65.9 1.1 2.8 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EEB05601.2 - 3.3e-16 58.7 3.8 8.4e-10 38.0 0.1 3.4 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.14 EEB05601.2 - 0.005 16.5 1.0 0.099 12.3 0.1 3.3 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EEB05601.2 - 0.015 14.9 0.2 0.72 9.6 0.0 3.4 4 0 0 4 4 4 0 FeoC like transcriptional regulator Sigma70_ner PF04546.8 EEB05601.2 - 0.06 12.9 5.5 0.026 14.1 0.8 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF2582 PF10771.4 EEB05601.2 - 0.11 12.3 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2582) GDPD PF03009.12 EEB05603.2 - 3e-72 243.1 0.0 4.7e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEB05603.2 - 3.1e-22 78.7 0.2 1.3e-07 31.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEB05603.2 - 4.7e-16 57.7 3.2 0.00097 18.8 0.0 6.4 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EEB05603.2 - 5.5e-16 58.2 0.5 3.2e-06 27.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEB05603.2 - 4.9e-14 52.3 0.3 1.8e-07 31.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) SPX PF03105.14 EEB05603.2 - 9.8e-11 41.9 6.5 9.2e-05 22.3 0.7 2.9 2 1 1 3 3 3 2 SPX domain Ank_3 PF13606.1 EEB05603.2 - 1.1e-09 37.6 3.1 1 9.8 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat ERCC4 PF02732.10 EEB05604.1 - 1.7e-07 31.0 0.9 5.3e-07 29.4 0.1 2.1 1 1 1 2 2 2 1 ERCC4 domain Prenyltrans_2 PF13249.1 EEB05605.1 - 3.7e-45 152.9 0.4 5.7e-12 46.0 0.0 4.8 2 2 4 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 EEB05605.1 - 5.6e-36 121.7 12.7 2.2e-10 39.8 0.0 6.6 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EEB05605.1 - 3.5e-32 110.6 2.9 9.7e-11 41.6 0.1 5.1 3 2 3 6 6 6 5 Prenyltransferase-like A2M_comp PF07678.9 EEB05605.1 - 8.8e-07 28.3 0.1 0.79 8.9 0.0 5.1 3 1 2 5 5 5 3 A-macroglobulin complement component Pec_lyase PF09492.5 EEB05605.1 - 1.2e-06 27.8 0.2 0.39 9.8 0.0 4.6 5 1 1 6 6 6 3 Pectic acid lyase Mago-bind PF09282.5 EEB05605.1 - 5e-06 25.9 0.2 0.035 13.6 0.0 3.1 3 0 0 3 3 3 2 Mago binding Mito_carr PF00153.22 EEB05607.2 - 7.2e-66 217.9 5.0 6.7e-23 80.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 EEB05608.1 - 1.9e-17 62.7 0.2 4.1e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S5_C PF03719.10 EEB05609.1 - 5.7e-24 83.1 0.0 3.7e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EEB05609.1 - 2.1e-13 49.7 1.0 9.5e-13 47.6 0.5 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Speriolin_C PF15059.1 EEB05609.1 - 0.023 14.6 0.3 0.043 13.8 0.2 1.4 1 0 0 1 1 1 0 Speriolin C-terminus Nexin_C PF08628.7 EEB05609.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Sorting nexin C terminal Ribosomal_L6 PF00347.18 EEB05610.1 - 1.5e-32 111.8 5.2 2.1e-19 69.7 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Chordopox_L2 PF05803.7 EEB05610.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus L2 protein adh_short PF00106.20 EEB05611.1 - 4.4e-25 88.5 0.0 8.5e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB05611.1 - 7.7e-11 42.2 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB05611.1 - 1.6e-08 34.4 0.3 3.3e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEB05611.1 - 4.1e-05 23.6 0.1 8.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEB05611.1 - 0.00038 19.4 0.3 0.00052 18.9 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EEB05611.1 - 0.0015 18.9 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EEB05611.1 - 0.0075 15.9 0.1 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EEB05611.1 - 0.021 13.7 0.1 0.058 12.3 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NmrA PF05368.8 EEB05611.1 - 0.029 13.6 0.0 0.89 8.7 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family TrkA_N PF02254.13 EEB05611.1 - 0.046 13.7 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.21 EEB05611.1 - 0.061 12.8 0.1 4.5 6.8 0.0 2.6 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EEB05611.1 - 0.089 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EEB05611.1 - 0.11 12.3 0.0 0.4 10.5 0.0 2.0 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mpv17_PMP22 PF04117.7 EEB05612.1 - 3.5e-23 81.0 4.5 7.4e-23 79.9 3.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Vps26 PF03643.10 EEB05613.1 - 1.1e-124 414.6 2.6 1.3e-124 414.4 1.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EEB05613.1 - 0.00023 20.9 3.1 0.0076 16.0 0.2 3.1 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain AAA_33 PF13671.1 EEB05614.1 - 2e-11 43.9 0.0 2.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EEB05614.1 - 5e-11 42.7 0.0 6.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EEB05614.1 - 6.2e-11 42.7 0.0 1.3e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB05614.1 - 7e-10 39.7 0.0 9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EEB05614.1 - 7.9e-06 25.6 0.0 9.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.10 EEB05614.1 - 0.00019 20.2 0.0 0.00027 19.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EEB05614.1 - 0.001 18.2 0.0 0.0017 17.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EEB05614.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain Cytidylate_kin2 PF13189.1 EEB05614.1 - 0.0018 18.2 0.2 0.05 13.5 0.0 2.2 1 1 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.24 EEB05614.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EEB05614.1 - 0.034 13.6 0.1 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 EEB05614.1 - 0.045 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EEB05614.1 - 0.047 13.8 0.1 0.16 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEB05614.1 - 0.049 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 EEB05614.1 - 0.051 12.2 0.1 0.055 12.1 0.0 1.3 1 1 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 EEB05614.1 - 0.06 12.9 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CoaE PF01121.15 EEB05614.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_28 PF13521.1 EEB05614.1 - 0.083 12.8 0.1 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EEB05614.1 - 0.084 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus tRNA_lig_kinase PF08303.6 EEB05614.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 tRNA ligase kinase domain HMG_box PF00505.14 EEB05615.1 - 5.1e-12 45.8 4.2 5.2e-09 36.2 0.3 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EEB05615.1 - 8.2e-09 35.7 3.9 0.00044 20.5 0.1 2.8 2 1 0 2 2 2 2 HMG-box domain Exonuc_VII_L PF02601.10 EEB05615.1 - 0.0014 17.9 0.5 0.0016 17.6 0.3 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Catalase-rel PF06628.7 EEB05615.1 - 0.039 13.8 0.2 0.53 10.1 0.0 2.6 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF3106 PF11304.3 EEB05615.1 - 2.2 8.7 6.8 3.8 7.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) OTCace PF00185.19 EEB05616.1 - 2.1e-45 154.4 0.4 3.1e-45 153.8 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EEB05616.1 - 1.1e-42 145.0 0.0 2.5e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.11 EEB05616.1 - 0.003 16.9 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Nro1 PF12753.2 EEB05616.1 - 0.018 14.0 0.5 3 6.7 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 OCD_Mu_crystall PF02423.10 EEB05616.1 - 0.033 12.9 0.3 0.053 12.2 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Herpes_UL95 PF03038.9 EEB05616.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 UL95 family DUF619 PF04768.8 EEB05617.1 - 2.2e-29 102.0 0.1 7.1e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EEB05617.1 - 1.6e-27 96.2 0.0 3.2e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EEB05617.1 - 9.1e-22 77.7 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EEB05617.1 - 0.0022 17.8 0.1 0.0093 15.8 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RNA_pol_Rpb2_6 PF00562.23 EEB05618.1 - 4.5e-122 407.5 0.0 7.7e-122 406.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEB05618.1 - 4.1e-62 208.7 0.1 6.8e-62 207.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEB05618.1 - 7.7e-42 142.8 0.0 1.8e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEB05618.1 - 1.1e-30 105.7 0.1 3.2e-30 104.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEB05618.1 - 7.4e-26 89.7 0.9 3.2e-25 87.7 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EEB05618.1 - 8.1e-19 67.1 0.1 1.9e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEB05618.1 - 2.9e-13 49.5 0.4 6.5e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PIP5K PF01504.13 EEB05619.1 - 4.6e-64 215.9 0.6 4.6e-64 215.9 0.4 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EEB05619.1 - 7.9e-25 87.4 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EEB05619.1 - 2.8e-15 55.9 9.9 2.8e-15 55.9 6.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.27 EEB05620.2 - 1.5e-36 122.9 6.3 1.2e-10 40.8 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEB05620.2 - 0.012 13.7 0.2 0.27 9.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3255 PF11631.3 EEB05620.2 - 0.068 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) FHA PF00498.21 EEB05621.1 - 6e-08 32.6 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain EnY2 PF10163.4 EEB05622.1 - 1.5e-18 66.4 0.2 2e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2202 PF09968.4 EEB05622.1 - 0.041 13.5 0.1 0.077 12.6 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized protein domain (DUF2202) Ofd1_CTDD PF10637.4 EEB05623.1 - 5.2e-77 258.5 0.0 9.9e-73 244.5 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EEB05623.1 - 3e-12 46.9 0.0 8.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEB05623.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PRP1_N PF06424.7 EEB05624.1 - 5.3e-47 159.4 2.5 5.3e-47 159.4 1.7 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EEB05624.1 - 4.1e-28 95.2 14.5 0.013 16.0 0.0 13.6 6 3 7 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05624.1 - 6.1e-18 64.9 1.9 0.0028 17.9 0.0 8.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05624.1 - 1.1e-13 51.3 3.7 0.03 15.0 0.4 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05624.1 - 1.4e-10 40.6 1.4 0.21 11.2 0.0 7.4 6 2 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 EEB05624.1 - 9.1e-08 31.4 7.2 7.1 6.8 0.0 9.3 11 0 0 11 11 11 1 Tetratricopeptide repeat Suf PF05843.9 EEB05624.1 - 3.3e-06 27.0 10.7 0.0066 16.2 0.0 4.8 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_1 PF00515.23 EEB05624.1 - 8e-06 25.2 0.0 2.7 7.7 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEB05624.1 - 1.1e-05 24.4 4.6 1.1e-05 24.4 3.2 5.0 3 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EEB05624.1 - 4e-05 23.4 2.1 74 3.9 0.0 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05624.1 - 0.00048 20.3 2.9 20 5.9 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat UPF0181 PF03701.9 EEB05624.1 - 0.0025 17.0 0.4 0.0068 15.6 0.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) TPR_8 PF13181.1 EEB05624.1 - 0.018 14.7 0.1 65 3.6 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB05624.1 - 0.026 14.6 0.6 16 5.6 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 EEB05624.1 - 0.17 11.8 6.7 13 5.6 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat UCH PF00443.24 EEB05625.1 - 5.9e-43 146.9 0.3 9.9e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB05625.1 - 8.3e-26 91.1 2.8 1.6e-25 90.1 0.4 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEB05625.1 - 8.2e-25 86.7 12.7 4e-20 71.6 2.4 3.3 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EEB05625.1 - 8.1e-22 76.4 0.5 7.9e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ThiF PF00899.16 EEB05626.1 - 3.4e-31 107.8 0.0 6e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.14 EEB05626.1 - 0.0047 16.0 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEB05626.1 - 0.0056 16.7 0.0 0.091 12.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEB05626.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRS4 PF10422.4 EEB05627.1 - 7e-11 41.9 20.5 7e-11 41.9 14.2 2.2 1 1 1 2 2 2 1 Monopolin complex subunit LRS4 DUF641 PF04859.7 EEB05627.1 - 2.8e-05 23.8 16.2 0.0012 18.6 0.4 3.0 3 1 0 3 3 3 2 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EEB05627.1 - 0.011 15.8 6.6 0.011 15.8 4.6 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF349 PF03993.7 EEB05627.1 - 0.037 14.1 1.4 0.037 14.1 1.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Reo_sigmaC PF04582.7 EEB05627.1 - 0.052 12.7 17.7 0.11 11.6 0.1 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Vps51 PF08700.6 EEB05627.1 - 0.093 12.5 11.4 1.3 8.9 3.6 3.2 3 1 0 3 3 3 0 Vps51/Vps67 Tropomyosin_1 PF12718.2 EEB05627.1 - 0.17 11.7 25.6 0.18 11.6 4.0 3.6 1 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 EEB05627.1 - 0.28 10.9 12.1 1.3 8.8 2.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 EEB05627.1 - 0.33 10.9 18.1 0.8 9.6 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ATG16 PF08614.6 EEB05627.1 - 0.36 10.6 23.7 0.12 12.1 6.7 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 EEB05627.1 - 0.63 9.1 23.9 1.3 8.2 8.8 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EEB05627.1 - 1.7 8.2 26.0 62 3.1 18.0 2.4 1 1 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EEB05627.1 - 1.7 7.8 25.2 4.7 6.3 5.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Phage_GP20 PF06810.6 EEB05627.1 - 2 7.8 21.3 0.95 8.8 1.9 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.3 EEB05627.1 - 6 6.7 24.1 1.2 9.0 6.4 3.1 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Sec20 PF03908.8 EEB05627.1 - 6.4 6.5 11.0 0.32 10.7 2.0 2.9 1 1 1 3 3 3 0 Sec20 APG6 PF04111.7 EEB05627.1 - 7.3 5.5 22.4 2.4 7.1 10.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EEB05627.1 - 7.4 6.5 8.3 13 5.7 0.1 3.5 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EEB05627.1 - 9.4 4.7 23.5 1.5e+02 0.7 16.3 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Pal1 PF08316.6 EEB05628.1 - 5.4e-29 101.4 0.6 2e-28 99.5 0.1 2.2 2 1 0 2 2 2 1 Pal1 cell morphology protein Pkinase PF00069.20 EEB05629.1 - 3.9e-43 147.4 0.0 7.4e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05629.1 - 4.4e-33 114.4 0.0 6.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB05629.1 - 0.0037 17.0 0.1 0.67 9.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF3535 PF12054.3 EEB05630.2 - 3.9e-99 332.2 9.3 5.6e-62 209.8 4.4 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EEB05630.2 - 4.2e-60 203.0 0.0 9.8e-60 201.8 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EEB05630.2 - 9.9e-19 65.7 8.1 0.0047 16.8 0.1 10.1 9 0 0 9 9 9 4 HEAT repeat Helicase_C PF00271.26 EEB05630.2 - 1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EEB05630.2 - 1.4e-09 38.0 0.4 0.0061 16.8 0.0 6.2 4 3 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EEB05630.2 - 3.5e-07 30.5 1.7 0.067 13.5 0.0 5.2 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEB05630.2 - 2e-05 24.8 7.3 0.94 10.0 0.0 6.6 7 1 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.3 EEB05630.2 - 2.5e-05 23.7 2.4 0.27 10.5 0.0 3.8 4 0 0 4 4 4 2 CLASP N terminal LRR_6 PF13516.1 EEB05631.1 - 1.7e-14 52.2 11.7 0.36 11.0 0.0 10.3 11 0 0 11 11 11 3 Leucine Rich repeat F-box-like PF12937.2 EEB05631.1 - 3.9e-11 42.5 2.3 1.4e-10 40.7 1.6 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EEB05631.1 - 5.8e-10 38.5 10.0 0.012 15.2 0.0 7.1 3 3 4 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EEB05631.1 - 3e-07 29.9 2.3 6.9e-07 28.7 0.8 2.3 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EEB05631.1 - 4.6e-07 29.4 13.9 0.088 12.5 0.0 6.5 3 2 5 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EEB05631.1 - 2.4e-06 26.7 21.0 8.6 6.8 0.5 10.5 10 3 0 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 EEB05631.1 - 0.00065 19.4 19.1 10 6.8 0.0 9.0 9 1 0 9 9 9 1 Leucine rich repeat RsgI_N PF12791.2 EEB05631.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Usp PF00582.21 EEB05632.1 - 3.3e-19 69.4 0.0 4.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family tRNA-synt_1d PF00750.14 EEB05633.2 - 7.3e-86 288.1 6.5 2.3e-85 286.5 4.5 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EEB05633.2 - 9.3e-23 80.4 1.3 1.8e-22 79.4 0.1 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain DUF2250 PF10007.4 EEB05633.2 - 0.0085 15.9 0.6 0.028 14.3 0.3 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) Arg_tRNA_synt_N PF03485.11 EEB05633.2 - 0.012 16.1 0.1 0.037 14.5 0.0 2.0 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain A2M_N PF01835.14 EEB05634.1 - 0.011 15.9 0.3 5.5 7.2 0.0 4.2 2 1 2 4 4 4 0 MG2 domain BTB PF00651.26 EEB05635.1 - 6.9e-09 35.6 0.0 1.9e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain KH_4 PF13083.1 EEB05636.1 - 0.0015 18.1 0.2 0.0038 16.8 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEB05636.1 - 0.01 15.4 0.1 0.044 13.4 0.0 2.1 2 0 0 2 2 2 0 KH domain KH_1 PF00013.24 EEB05636.1 - 0.014 15.0 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 KH domain MMR_HSR1 PF01926.18 EEB05638.1 - 1.7e-16 60.1 0.1 1.1e-14 54.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB05638.1 - 2.3e-09 36.7 0.0 4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 EEB05638.1 - 2.7e-06 26.6 0.0 5.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EEB05638.1 - 5e-06 25.7 0.0 8.2e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EEB05638.1 - 0.0017 18.1 0.8 0.091 12.5 0.0 2.7 2 1 1 3 3 3 1 Dynamin family ArgK PF03308.11 EEB05638.1 - 0.011 14.5 0.1 0.019 13.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein IIGP PF05049.8 EEB05638.1 - 0.023 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EEB05638.1 - 0.08 12.9 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EEB05638.1 - 0.11 12.7 0.0 0.47 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EEB05638.1 - 0.14 11.8 0.2 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aldedh PF00171.17 EEB05639.1 - 2.4e-19 69.0 1.3 7.7e-15 54.1 0.1 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1542 PF07564.6 EEB05639.1 - 0.002 18.1 2.6 0.005 16.8 0.9 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) DUF1487 PF07368.6 EEB05639.1 - 0.033 13.4 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 EEB05640.1 - 1.1e-60 205.0 0.0 1.6e-59 201.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05640.1 - 6.9e-27 94.1 0.0 7.3e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EEB05640.1 - 4.4e-05 22.6 0.4 0.0045 16.0 0.0 2.5 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEB05640.1 - 7.1e-05 21.8 0.0 0.00013 21.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EEB05640.1 - 7.8e-05 23.1 0.4 0.00016 22.0 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EEB05640.1 - 0.0087 15.8 0.3 0.084 12.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB05640.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEB05640.1 - 0.061 12.1 0.4 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EEB05640.1 - 0.13 11.5 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family JAB PF01398.16 EEB05641.1 - 7.8e-09 35.2 0.0 1.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dec-1 PF04624.9 EEB05641.1 - 0.31 10.7 4.2 0.74 9.4 2.9 1.5 1 0 0 1 1 1 0 Dec-1 repeat Septin PF00735.13 EEB05642.1 - 1.3e-109 365.5 0.4 1.6e-109 365.2 0.3 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEB05642.1 - 5.8e-09 35.9 0.0 1.4e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEB05642.1 - 2.2e-06 26.9 0.0 4.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEB05642.1 - 3.1e-06 26.7 0.2 3.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEB05642.1 - 8e-06 25.7 1.4 0.02 14.7 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EEB05642.1 - 1.4e-05 24.3 0.0 2.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_14 PF13173.1 EEB05642.1 - 9.8e-05 22.2 0.0 0.00031 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EEB05642.1 - 0.00011 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EEB05642.1 - 0.00048 20.0 0.0 0.0014 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEB05642.1 - 0.00071 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EEB05642.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 EEB05642.1 - 0.0017 18.3 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEB05642.1 - 0.0022 16.9 0.1 0.0046 15.8 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EEB05642.1 - 0.0024 17.3 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEB05642.1 - 0.0026 17.9 0.0 0.0064 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EEB05642.1 - 0.0026 18.2 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EEB05642.1 - 0.003 17.2 0.1 0.0064 16.2 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RHD3 PF05879.7 EEB05642.1 - 0.0039 15.1 0.0 0.0067 14.4 0.0 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Gtr1_RagA PF04670.7 EEB05642.1 - 0.0075 15.4 0.2 0.057 12.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GBP PF02263.14 EEB05642.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain RNA_helicase PF00910.17 EEB05642.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EEB05642.1 - 0.015 14.8 0.1 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 EEB05642.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EEB05642.1 - 0.016 14.0 0.1 0.037 12.8 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.2 EEB05642.1 - 0.016 14.2 0.0 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_17 PF13207.1 EEB05642.1 - 0.016 15.9 1.3 0.044 14.5 0.9 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB05642.1 - 0.021 15.1 0.4 0.078 13.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEB05642.1 - 0.023 13.9 0.1 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.16 EEB05642.1 - 0.023 14.1 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase DUF815 PF05673.8 EEB05642.1 - 0.025 13.5 0.0 0.051 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EEB05642.1 - 0.051 13.0 0.0 0.87 9.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EEB05642.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEB05642.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EEB05642.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EEB05642.1 - 0.09 12.4 0.0 0.68 9.5 0.0 2.3 2 1 1 3 3 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EEB05642.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EEB05642.1 - 0.13 12.0 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Zn_clus PF00172.13 EEB05643.2 - 1.3e-08 34.6 9.0 2.2e-08 33.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF390 PF04094.9 EEB05643.2 - 1.9 6.3 6.0 2.7 5.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) WD40 PF00400.27 EEB05644.1 - 7e-22 76.4 16.5 1.5e-07 31.0 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEB05644.1 - 1.5e-06 28.1 1.6 0.0032 17.2 0.5 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Glyco_hydro_81 PF03639.8 EEB05645.1 - 2.4e-192 640.6 16.0 3.2e-192 640.2 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Carb_bind PF10645.4 EEB05645.1 - 2.6e-49 164.8 55.4 5.8e-17 61.2 9.6 3.6 3 0 0 3 3 3 3 Carbohydrate binding Sod_Cu PF00080.15 EEB05646.1 - 1.8e-44 151.3 2.0 2.1e-44 151.1 1.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) E1-E2_ATPase PF00122.15 EEB05647.1 - 4.5e-20 71.6 0.3 4.5e-20 71.6 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EEB05647.1 - 7.7e-15 55.5 0.0 5.7e-14 52.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB05647.1 - 1e-14 55.4 0.4 2.5e-11 44.4 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB05647.1 - 1.8e-12 47.0 0.0 6.2e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEB05647.1 - 4e-05 23.3 0.2 0.00015 21.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cut8_N PF14482.1 EEB05647.1 - 0.076 13.0 0.0 0.076 13.0 0.0 3.3 4 0 0 4 4 4 0 Cut8 proteasome-binding domain MKT1_C PF12246.3 EEB05648.2 - 1.1e-18 67.0 0.0 1.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EEB05648.2 - 3.8e-15 55.9 1.7 3.7e-13 49.6 0.0 4.0 4 1 0 4 4 4 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EEB05648.2 - 1.6e-09 37.6 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEB05648.2 - 4.6e-06 26.8 0.0 2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain His_kinase PF06580.8 EEB05648.2 - 0.07 13.0 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase Mito_carr PF00153.22 EEB05649.1 - 1.3e-57 191.4 4.1 2.7e-18 65.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF427 PF04248.7 EEB05650.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Aminotran_3 PF00202.16 EEB05651.1 - 1.7e-38 132.3 0.0 5.9e-37 127.2 0.0 2.7 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EEB05651.1 - 1.3e-31 109.7 0.0 3.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_photolyase PF00875.13 EEB05651.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA photolyase Aldedh PF00171.17 EEB05652.1 - 1.2e-154 515.1 1.1 1.3e-154 514.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sel1 PF08238.7 EEB05653.2 - 3.4e-07 30.6 1.6 0.025 15.1 0.0 5.3 5 0 0 5 5 5 1 Sel1 repeat TPR_12 PF13424.1 EEB05653.2 - 8.3e-06 25.6 9.7 0.16 11.9 0.5 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05653.2 - 2.6e-05 23.6 5.8 0.019 14.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05653.2 - 0.00024 21.0 3.6 0.23 11.7 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05653.2 - 0.0013 18.3 13.0 0.25 11.0 0.1 4.4 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.1 EEB05653.2 - 0.0028 17.3 8.8 9.1 6.3 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEB05653.2 - 0.0029 17.4 3.2 0.74 9.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05653.2 - 0.0067 16.2 9.1 1.7 8.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05653.2 - 0.0087 15.6 1.1 0.46 10.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05653.2 - 0.0093 16.6 5.6 0.9 10.2 0.4 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05653.2 - 0.04 14.5 6.0 11 6.9 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05653.2 - 0.48 11.0 8.7 9.1 6.9 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB05653.2 - 0.81 9.8 4.6 6.2 7.0 0.1 3.4 2 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Hat1_N PF10394.4 EEB05654.2 - 6.8e-21 75.0 1.4 1.6e-20 73.8 0.3 2.1 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EEB05654.2 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EEB05654.2 - 0.017 14.3 0.4 0.033 13.4 0.3 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_7 PF13508.1 EEB05654.2 - 0.021 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB05654.2 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1900 PF08954.6 EEB05655.1 - 5.5e-49 165.1 0.0 1.9e-48 163.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EEB05655.1 - 8.2e-33 111.8 0.0 1.4e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EEB05655.1 - 5.4e-24 83.1 5.3 3.2e-08 33.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat FlxA PF14282.1 EEB05655.1 - 0.041 13.8 2.5 0.086 12.7 1.7 1.6 1 0 0 1 1 1 0 FlxA-like protein MerR-DNA-bind PF09278.6 EEB05655.1 - 0.34 11.3 2.6 22 5.5 3.1 2.3 1 1 1 2 2 2 0 MerR, DNA binding DUF3635 PF12330.3 EEB05656.1 - 1.6e-19 69.7 0.2 4.4e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Ish1 PF10281.4 EEB05657.1 - 1.1e-16 60.5 4.9 7.3e-06 25.9 0.1 6.1 6 0 0 6 6 6 3 Putative stress-responsive nuclear envelope protein Phage_GPO PF05929.6 EEB05657.1 - 0.15 11.2 0.6 0.23 10.6 0.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3646 PF12362.3 EEB05657.1 - 0.2 11.6 2.0 0.35 10.8 0.9 1.7 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal DUF4337 PF14235.1 EEB05657.1 - 0.34 10.7 1.8 0.69 9.7 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DER1 PF04511.10 EEB05658.1 - 5.3e-29 101.1 9.8 6e-29 100.9 6.8 1.0 1 0 0 1 1 1 1 Der1-like family Cation_ATPase_C PF00689.16 EEB05658.1 - 0.0087 15.5 4.6 0.011 15.2 3.2 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cohesin_load PF10345.4 EEB05659.1 - 3.9e-62 210.3 18.7 3.8e-61 207.0 13.0 1.9 1 1 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 EEB05659.1 - 0.015 15.2 4.7 2.3 8.2 0.2 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05659.1 - 0.055 13.9 0.2 16 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TGT PF01702.13 EEB05660.1 - 1.1e-88 296.5 0.2 1.4e-88 296.2 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.6 EEB05661.1 - 2.6e-61 207.3 6.4 1.4e-60 204.9 4.4 2.0 1 1 0 1 1 1 1 Mis6 His_Phos_1 PF00300.17 EEB05662.1 - 1.5e-30 106.3 0.0 2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PUF PF00806.14 EEB05663.1 - 3.6e-62 202.4 10.8 1.5e-08 33.6 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 EEB05663.1 - 0.12 12.3 0.8 0.98 9.5 0.0 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 2 zf-Tim10_DDP PF02953.10 EEB05664.1 - 3.2e-24 83.9 5.5 3.8e-24 83.7 3.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EEB05664.1 - 0.016 14.6 3.5 0.02 14.3 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RecQ5 PF06959.6 EEB05665.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) TGF_beta PF00019.15 EEB05665.1 - 0.12 12.6 0.2 0.54 10.5 0.1 1.8 1 1 1 2 2 2 0 Transforming growth factor beta like domain Ribosomal_L28e PF01778.12 EEB05666.1 - 9e-30 103.4 0.6 2.4e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EEB05666.1 - 2.5e-28 98.0 11.3 2.5e-28 98.0 7.9 2.6 3 0 0 3 3 3 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 EEB05666.1 - 0.016 14.6 0.2 0.016 14.6 0.2 1.6 2 0 0 2 2 2 0 Conserved carboxylase domain DUF2462 PF09495.5 EEB05666.1 - 0.039 14.6 0.4 0.039 14.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Na_trans_assoc PF06512.8 EEB05666.1 - 0.1 12.5 9.7 0.15 11.9 6.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.7 EEB05666.1 - 0.47 8.3 26.5 0.64 7.8 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family GRA6 PF05084.8 EEB05666.1 - 2 7.9 6.8 3 7.3 4.7 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF2146 PF10220.4 EEB05666.1 - 6.5 4.5 10.1 8.1 4.2 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Pkinase PF00069.20 EEB05667.2 - 1.1e-36 126.2 0.0 7.7e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05667.2 - 9.4e-17 60.9 0.0 2.2e-07 30.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase HALZ PF02183.13 EEB05667.2 - 0.018 14.7 1.4 0.035 13.8 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SNO PF01174.14 EEB05668.1 - 5e-48 163.2 0.0 5.9e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEB05668.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EEB05668.1 - 6.2e-05 22.5 0.0 0.00026 20.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 EEB05668.1 - 0.00045 20.0 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 EEB05668.1 - 0.00065 19.2 0.8 0.016 14.6 0.6 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EEB05668.1 - 0.00086 18.7 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 EEB05668.1 - 0.034 13.4 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative amidotransferase RNA_pol_I_TF PF04090.7 EEB05669.1 - 7.1e-29 100.5 0.0 2.7e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_6 PF13174.1 EEB05669.1 - 1.3e-05 25.3 3.0 0.0053 17.1 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEB05669.1 - 0.00038 20.2 2.0 0.31 10.9 0.6 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05669.1 - 0.003 17.3 5.5 1.2 9.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.1 EEB05669.1 - 0.0032 16.9 0.0 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_19 PF14559.1 EEB05669.1 - 0.0041 17.4 0.6 0.052 13.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05669.1 - 0.0052 17.4 2.7 7.2 7.4 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05669.1 - 0.016 15.8 4.3 3.9 8.3 0.0 3.8 3 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB05669.1 - 0.12 12.5 0.0 3.3 7.9 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.2 EEB05670.1 - 1.6e-13 50.7 5.6 2.2e-08 34.3 0.5 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEB05670.1 - 9.8e-13 48.2 5.0 2.1e-07 31.2 0.4 3.2 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEB05670.1 - 8.6e-12 44.2 6.0 9.5e-07 28.3 0.8 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEB05670.1 - 1.3e-09 38.0 3.4 4.5e-05 23.5 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB05670.1 - 2.3e-08 33.4 6.7 1.3e-05 24.9 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EEB05670.1 - 0.00011 21.7 0.1 0.0016 18.0 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Cor1 PF04803.7 EEB05670.1 - 0.051 13.3 1.2 0.11 12.2 0.8 1.5 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region GUCT PF08152.7 EEB05670.1 - 0.061 13.3 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 GUCT (NUC152) domain Pribosyltran PF00156.22 EEB05671.1 - 7.4e-16 58.0 0.4 1.8e-15 56.7 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEB05671.1 - 0.0081 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF619 PF04768.8 EEB05672.1 - 2.5e-48 163.6 0.0 4.6e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Sld5 PF05916.6 EEB05673.1 - 6.2e-24 84.3 0.7 1.2e-23 83.4 0.5 1.4 1 0 0 1 1 1 1 GINS complex protein Lant_dehyd_C PF04738.8 EEB05673.1 - 0.00063 18.1 0.1 0.00082 17.7 0.1 1.1 1 0 0 1 1 1 1 Lantibiotic dehydratase, C terminus DUF2605 PF10792.4 EEB05673.1 - 0.0052 16.4 0.1 0.0098 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2605) Nbl1_Borealin_N PF10444.4 EEB05674.1 - 3.2e-18 64.8 1.3 4.8e-18 64.2 0.9 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal CBFB_NFYA PF02045.10 EEB05675.1 - 2.2e-27 95.3 9.5 4.8e-27 94.2 6.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PAT1 PF09770.4 EEB05675.1 - 2.4 6.3 28.3 3.2 5.8 19.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PET PF06297.9 EEB05675.1 - 6.4 6.4 11.6 7.4 6.2 6.7 2.0 1 1 1 2 2 2 0 PET Domain TspO_MBR PF03073.10 EEB05676.1 - 3e-36 124.1 13.5 3.8e-36 123.8 9.4 1.1 1 0 0 1 1 1 1 TspO/MBR family BAR PF03114.13 EEB05677.1 - 4.3e-58 196.5 0.4 5.4e-58 196.2 0.3 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EEB05677.1 - 0.038 13.3 0.3 0.071 12.4 0.2 1.6 1 1 0 1 1 1 0 Arfaptin-like domain DUF4511 PF14974.1 EEB05677.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) HisKA_3 PF07730.8 EEB05677.1 - 0.34 11.2 2.7 1.7 9.0 0.3 2.9 3 0 0 3 3 3 0 Histidine kinase DUF3546 PF12066.3 EEB05678.2 - 4.4e-08 33.1 3.3 1.1e-07 31.7 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) 7TMR-HDED PF07697.6 EEB05678.2 - 0.019 14.7 2.0 0.72 9.5 0.2 2.5 3 0 0 3 3 3 0 7TM-HD extracellular RRM_6 PF14259.1 EEB05678.2 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 EEB05679.2 - 2.6e-17 62.2 3.8 3.6e-06 26.5 0.0 4.7 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EEB05679.2 - 9.4e-17 59.5 1.5 0.00074 19.2 0.0 6.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05679.2 - 1.1e-11 43.8 1.5 0.0054 16.2 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05679.2 - 6.7e-10 39.3 0.6 0.0014 19.2 0.1 4.6 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05679.2 - 1.6e-07 31.3 1.8 0.038 14.6 0.2 4.8 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05679.2 - 4.8e-06 26.3 5.0 0.16 12.2 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05679.2 - 7.3e-05 23.0 5.4 0.53 10.6 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB05679.2 - 0.00022 21.0 1.1 1.7 8.5 0.0 3.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05679.2 - 0.00099 18.7 1.7 13 5.8 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB05679.2 - 0.0061 16.6 2.8 0.92 9.6 0.2 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EEB05679.2 - 0.0099 15.9 0.0 0.0099 15.9 0.0 3.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05679.2 - 0.01 16.2 1.3 6.7 7.3 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat DUF627 PF04781.7 EEB05679.2 - 0.042 13.4 0.5 5.6 6.6 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF627) MIT PF04212.13 EEB05679.2 - 0.31 10.9 4.7 35 4.3 0.1 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 EEB05679.2 - 0.4 10.9 5.8 10 6.4 0.2 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_8 PF13181.1 EEB05679.2 - 0.42 10.5 5.7 50 4.0 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1674 PF07896.7 EEB05680.2 - 1.8e-12 47.2 4.9 3.4e-12 46.3 3.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Pkinase PF00069.20 EEB05681.1 - 4.9e-57 193.0 0.8 4.8e-38 130.8 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05681.1 - 1.5e-29 102.8 0.5 1.1e-20 73.8 0.1 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEB05681.1 - 3.4e-06 26.2 0.0 4.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB05681.1 - 0.34 10.5 0.1 0.65 9.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phosphodiest PF01663.17 EEB05682.1 - 8.4e-75 252.3 1.5 9.9e-75 252.1 1.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPP_enzyme_N PF02776.13 EEB05683.2 - 1.9e-47 160.9 0.2 4e-47 159.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEB05683.2 - 1.9e-31 108.6 0.0 8.1e-31 106.6 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEB05683.2 - 3.8e-23 81.7 0.1 9.5e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEB05683.2 - 0.00058 18.8 0.1 0.0012 17.8 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.11 EEB05683.2 - 0.02 14.4 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Peripla_BP_4 PF13407.1 EEB05683.2 - 0.12 11.7 0.7 0.25 10.6 0.0 1.9 3 0 0 3 3 3 0 Periplasmic binding protein domain Pyridox_oxase_2 PF12766.2 EEB05684.2 - 1.5e-20 73.3 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1935 PF09149.5 EEB05685.1 - 0.047 13.6 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) Amastin PF07344.6 EEB05685.1 - 0.071 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein His_Phos_2 PF00328.17 EEB05687.1 - 1.7e-34 119.6 0.1 2.1e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 EEB05688.1 - 5.8e-42 143.0 0.0 1.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB05688.1 - 9.7e-07 28.9 0.5 0.00025 21.1 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEB05688.1 - 1.8e-06 27.9 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEB05688.1 - 3.5e-06 26.7 0.1 1.4e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EEB05688.1 - 2e-05 23.6 0.0 3.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EEB05688.1 - 0.00014 21.8 0.5 0.00059 19.8 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EEB05688.1 - 0.00043 19.4 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEB05688.1 - 0.0024 17.8 0.1 0.0054 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain KaiC PF06745.8 EEB05688.1 - 0.0038 16.3 0.3 0.32 10.0 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_17 PF13207.1 EEB05688.1 - 0.0041 17.9 0.9 0.017 15.9 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEB05688.1 - 0.0041 17.0 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEB05688.1 - 0.0049 16.2 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EEB05688.1 - 0.0062 16.6 0.0 0.089 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EEB05688.1 - 0.0062 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EEB05688.1 - 0.0084 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEB05688.1 - 0.0094 15.3 1.5 0.38 10.1 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EEB05688.1 - 0.014 15.1 1.3 0.02 14.6 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain Sigma54_activat PF00158.21 EEB05688.1 - 0.015 14.7 0.0 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEB05688.1 - 0.016 14.0 0.1 0.058 12.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.6 EEB05688.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EEB05688.1 - 0.026 13.2 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EEB05688.1 - 0.027 14.7 0.6 0.053 13.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EEB05688.1 - 0.041 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEB05688.1 - 0.063 12.8 0.2 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEB05688.1 - 0.081 12.1 0.1 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EEB05688.1 - 0.11 12.1 0.3 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 EEB05688.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KH_1 PF00013.24 EEB05689.1 - 1.9e-45 152.3 3.0 4.7e-15 54.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEB05689.1 - 1.4e-33 113.9 3.5 9.4e-11 41.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEB05689.1 - 1.8e-13 49.8 0.1 0.0013 18.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEB05689.1 - 1.2e-09 37.6 1.0 0.081 12.5 0.0 3.4 3 0 0 3 3 3 3 KH domain SLS PF14611.1 EEB05689.1 - 0.0012 18.3 0.1 0.38 10.1 0.0 3.4 4 0 0 4 4 4 1 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.1 EEB05689.1 - 0.014 15.1 0.7 28 4.6 0.0 3.3 3 0 0 3 3 3 0 NusA-like KH domain Aminotran_1_2 PF00155.16 EEB05690.1 - 1.2e-77 261.3 0.0 1.4e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FA_hydroxylase PF04116.8 EEB05692.1 - 1.4e-12 47.9 18.9 1.4e-12 47.9 13.1 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily Pkinase PF00069.20 EEB05693.1 - 1.5e-65 220.9 0.0 1.9e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05693.1 - 6.1e-25 87.7 0.0 8.2e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05693.1 - 1.5e-07 30.6 0.0 3.7e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB05693.1 - 0.00059 19.6 0.8 0.0049 16.6 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEB05693.1 - 0.01 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEB05693.1 - 0.11 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.1 EEB05694.1 - 1.7e-10 40.8 0.1 2.4e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EEB05694.1 - 2.5e-08 32.6 0.1 5.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EEB05694.1 - 2.3e-07 30.1 1.2 4.9e-05 22.8 0.5 2.8 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EEB05694.1 - 1.6e-06 27.1 0.3 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEB05694.1 - 1.5e-05 24.5 0.8 0.00032 20.2 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair TerB PF05099.8 EEB05694.1 - 0.033 13.9 0.2 0.036 13.8 0.1 1.0 1 0 0 1 1 1 0 Tellurite resistance protein TerB JAB PF01398.16 EEB05695.2 - 2.4e-26 91.6 0.0 3.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEB05695.2 - 1.5e-05 24.4 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Coq4 PF05019.8 EEB05696.1 - 1.2e-96 321.8 0.0 1.4e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Spb1_C PF07780.7 EEB05697.1 - 1.1e-67 227.6 34.8 1.1e-67 227.6 24.1 3.9 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 EEB05697.1 - 1.5e-55 187.9 0.0 7e-55 185.8 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EEB05697.1 - 1.2e-49 167.9 5.7 1.2e-49 167.9 4.0 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) CobU PF02283.11 EEB05698.1 - 0.069 12.5 0.2 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SlyX PF04102.7 EEB05698.1 - 0.13 12.6 4.9 5.3 7.4 0.0 4.4 4 1 1 5 5 5 0 SlyX DUF479 PF04336.7 EEB05698.1 - 0.26 11.3 4.7 1.2 9.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF479 DivIVA PF05103.8 EEB05698.1 - 5.8 6.9 14.4 1.6 8.7 2.0 4.0 3 2 0 3 3 3 0 DivIVA protein DUF2015 PF09435.5 EEB05700.1 - 1.6e-31 108.7 0.5 2.7e-31 108.0 0.4 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EEB05701.1 - 2.2e-34 118.3 0.5 2.5e-34 118.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family PINIT PF14324.1 EEB05702.1 - 3.9e-35 121.0 1.2 1.9e-34 118.7 0.1 2.2 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 EEB05702.1 - 9.9e-23 79.4 4.1 1.7e-22 78.6 2.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EEB05702.1 - 4.9e-06 25.9 1.5 6.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 EEB05702.1 - 4.9e-06 25.9 0.8 9.5e-06 25.0 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PDCD2_C PF04194.8 EEB05702.1 - 0.06 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain MCM_bind PF09739.4 EEB05703.1 - 6.8e-27 93.4 1.3 1.1e-26 92.7 0.9 1.3 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EEB05703.1 - 5.5e-24 84.3 0.0 1.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Putative alanine racemase Rep_fac_C PF08542.6 EEB05704.1 - 1.1e-18 67.0 0.0 2.6e-18 65.7 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEB05704.1 - 4.1e-13 49.3 0.0 6.5e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEB05704.1 - 1.1e-11 45.0 0.1 2.3e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEB05704.1 - 3.5e-07 30.1 0.0 8.9e-07 28.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEB05704.1 - 4.3e-06 25.9 0.1 6.4e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EEB05704.1 - 8.4e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EEB05704.1 - 1.2e-05 25.3 0.1 0.00019 21.4 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EEB05704.1 - 2.5e-05 24.4 0.1 0.0036 17.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEB05704.1 - 4.5e-05 23.0 0.1 0.012 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_3 PF07726.6 EEB05704.1 - 5.4e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEB05704.1 - 6e-05 21.9 0.1 0.079 11.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EEB05704.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EEB05704.1 - 0.00015 21.2 0.1 0.1 11.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EEB05704.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEB05704.1 - 0.0038 16.4 0.1 0.064 12.3 0.0 2.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EEB05704.1 - 0.0039 16.9 0.3 0.067 12.8 0.1 2.3 1 1 0 2 2 2 1 NTPase FtsK_SpoIIIE PF01580.13 EEB05704.1 - 0.005 16.3 0.1 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EEB05704.1 - 0.0051 16.5 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SAGA-Tad1 PF12767.2 EEB05704.1 - 0.0082 15.8 0.2 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ArgK PF03308.11 EEB05704.1 - 0.028 13.1 0.1 0.12 11.1 0.0 2.0 1 1 1 2 2 2 0 ArgK protein DEAD PF00270.24 EEB05704.1 - 0.028 13.8 0.2 0.7 9.3 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EEB05704.1 - 0.038 13.7 0.2 3.7 7.2 0.1 3.2 2 2 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 EEB05704.1 - 0.049 13.5 0.1 0.3 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEB05704.1 - 0.14 10.9 0.3 0.28 10.0 0.1 1.6 1 1 0 1 1 1 0 NB-ARC domain Abi PF02517.11 EEB05705.1 - 1.6e-17 63.3 7.8 8.5e-17 61.0 2.0 2.6 2 0 0 2 2 2 2 CAAX protease self-immunity RNA_pol_L_2 PF13656.1 EEB05706.1 - 5.1e-34 115.5 0.1 6.8e-34 115.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEB05706.1 - 2.2e-13 49.1 0.0 3.1e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fasciclin PF02469.17 EEB05707.1 - 1.9e-24 86.0 1.9 4.2e-10 39.7 0.0 6.3 5 2 0 5 5 5 4 Fasciclin domain Ribosomal_S3Ae PF01015.13 EEB05708.1 - 1.9e-78 262.2 5.9 2.2e-78 262.0 4.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF1810 PF08837.6 EEB05708.1 - 0.027 14.0 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) DUF4168 PF13767.1 EEB05708.1 - 0.037 14.6 1.0 1.2 9.7 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) mRNA_cap_C PF03919.10 EEB05708.1 - 0.049 13.9 0.1 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Abhydrolase_6 PF12697.2 EEB05709.1 - 4.5e-32 111.7 0.0 5.3e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB05709.1 - 5.2e-17 62.1 0.0 3.9e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEB05709.1 - 3.3e-14 52.8 0.0 9.5e-14 51.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEB05709.1 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EEB05709.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EEB05709.1 - 0.0091 15.3 0.0 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.6 EEB05709.1 - 0.034 12.9 0.1 0.14 10.9 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase DUF2048 PF09752.4 EEB05709.1 - 0.052 12.4 0.0 0.74 8.6 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2048) DUF915 PF06028.6 EEB05709.1 - 0.07 12.2 0.0 0.74 8.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 EEB05709.1 - 0.081 11.2 0.1 0.43 8.8 0.0 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 EEB05709.1 - 0.089 12.3 0.0 0.48 9.9 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EEB05709.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) YEATS PF03366.11 EEB05710.1 - 3.2e-26 90.8 0.4 5.3e-26 90.1 0.2 1.4 1 0 0 1 1 1 1 YEATS family PDZ_1 PF12812.2 EEB05712.1 - 5.8e-43 144.6 0.0 6e-31 106.1 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EEB05712.1 - 1.7e-15 56.6 1.6 9.3e-06 25.4 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin_2 PF13365.1 EEB05712.1 - 3.5e-12 46.3 0.0 4.5e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EEB05712.1 - 8.1e-10 38.7 0.0 0.00055 20.0 0.0 3.9 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 EEB05712.1 - 0.00029 20.2 0.0 0.001 18.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.1 EEB05712.1 - 0.00083 19.1 0.7 0.071 12.9 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 EEB05712.1 - 0.004 16.7 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin DUF31 PF01732.11 EEB05712.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EEB05712.1 - 0.21 9.9 0.1 0.49 8.7 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 PCI PF01399.22 EEB05713.1 - 3e-18 66.0 0.5 1.7e-17 63.6 0.0 2.4 2 1 0 2 2 2 1 PCI domain TPR_16 PF13432.1 EEB05713.1 - 2.5e-05 24.8 7.5 0.011 16.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05713.1 - 0.0079 15.9 0.8 1.6 8.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EEB05713.1 - 0.021 14.5 0.5 0.06 13.0 0.1 1.9 2 0 0 2 2 2 0 Archaeal ATPase DUF4578 PF15147.1 EEB05713.1 - 0.17 12.2 0.3 0.66 10.3 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4578) TPR_2 PF07719.12 EEB05713.1 - 3.1 7.9 6.3 33 4.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05713.1 - 8.7 7.0 6.5 27 5.4 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat SWIB PF02201.13 EEB05714.1 - 3.3e-23 81.1 0.3 1.3e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain FGF-BP1 PF06473.7 EEB05715.1 - 1.8 8.1 15.6 0.07 12.7 6.1 1.8 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) TAF4 PF05236.9 EEB05716.2 - 4.3e-57 193.3 5.5 5.1e-57 193.1 3.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF1657 PF07870.6 EEB05716.2 - 0.011 15.4 0.1 0.075 12.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) UCH PF00443.24 EEB05717.1 - 8.7e-44 149.6 0.1 1.7e-43 148.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB05717.1 - 2.7e-13 50.0 0.0 1.1e-11 44.6 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEB05717.1 - 4.8e-10 39.3 11.5 4.8e-10 39.3 7.9 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Hid1 PF12722.2 EEB05718.1 - 1.3 6.6 14.2 1.3 6.6 9.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med25_VWA PF11265.3 EEB05718.1 - 1.6 7.7 6.5 0.61 9.0 2.5 1.7 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A DUF4407 PF14362.1 EEB05718.1 - 2.9 6.7 7.7 3.5 6.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2383 PF09537.5 EEB05718.1 - 3.4 7.9 6.7 9.7 6.4 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Nop PF01798.13 EEB05719.1 - 1.3e-58 196.5 1.0 3.1e-58 195.3 0.7 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEB05719.1 - 7.1e-28 96.1 0.0 1.5e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEB05719.1 - 4.9e-21 74.6 0.9 4.9e-21 74.6 0.6 2.3 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Baculo_PEP_C PF04513.7 EEB05719.1 - 0.024 14.4 1.8 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAGA_bind PF06217.7 EEB05719.1 - 0.46 10.4 13.0 0.66 9.8 9.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EEB05719.1 - 1.9 8.1 37.3 3.4 7.2 25.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 EEB05719.1 - 2 7.8 16.9 3 7.3 11.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EEB05719.1 - 5.6 6.2 24.5 8.2 5.7 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RGS PF00615.14 EEB05720.1 - 1.4e-05 25.1 0.2 9.5e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 Regulator of G protein signaling domain Bd3614-deam PF14439.1 EEB05720.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase PrgI PF12666.2 EEB05720.1 - 0.4 10.8 2.1 1.7 8.8 1.5 2.0 1 1 0 1 1 1 0 PrgI family protein INO80_Ies4 PF08193.6 EEB05721.1 - 2.9e-18 66.6 11.4 2.9e-18 66.6 7.9 4.4 1 1 3 4 4 4 1 INO80 complex subunit Ies4 Glycos_transf_1 PF00534.15 EEB05722.1 - 1.3e-19 70.2 0.0 2.1e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEB05722.1 - 1.2e-09 38.4 0.0 1.2e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEB05722.1 - 1.5e-06 28.0 0.1 1.2e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Ribosomal_L6 PF00347.18 EEB05723.1 - 2.3e-32 111.2 5.1 3.3e-19 69.1 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Chordopox_L2 PF05803.7 EEB05723.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus L2 protein Ribosomal_L29 PF00831.18 EEB05724.1 - 1.4e-20 72.6 3.2 1.4e-20 72.6 2.2 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein Dynamitin PF04912.9 EEB05724.1 - 0.0028 16.5 1.1 0.0031 16.3 0.7 1.1 1 0 0 1 1 1 1 Dynamitin GAS PF13851.1 EEB05724.1 - 0.0041 16.3 4.3 0.0041 16.3 3.0 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1013 PF06242.6 EEB05724.1 - 0.042 13.8 3.2 0.052 13.5 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Mhr1 PF12829.2 EEB05724.1 - 0.057 13.2 1.0 0.14 11.9 0.2 2.1 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination HATPase_c_5 PF14501.1 EEB05724.1 - 0.082 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 GHKL domain DUF4404 PF14357.1 EEB05724.1 - 0.13 12.7 0.5 0.13 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Nup88 PF10168.4 EEB05724.1 - 0.13 10.0 5.4 0.15 9.8 3.7 1.0 1 0 0 1 1 1 0 Nuclear pore component Ribosomal_S9 PF00380.14 EEB05724.1 - 0.15 12.3 3.1 0.37 11.0 2.1 1.7 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Prefoldin PF02996.12 EEB05724.1 - 0.16 11.6 7.7 0.59 9.7 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit Spectrin PF00435.16 EEB05724.1 - 0.19 12.0 2.2 4.8 7.5 0.1 2.0 1 1 1 2 2 2 0 Spectrin repeat DXP_synthase_N PF13292.1 EEB05724.1 - 0.36 9.7 1.5 4.2 6.2 0.1 2.0 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase CENP-H PF05837.7 EEB05724.1 - 3.5 7.8 8.1 2.6e+02 1.8 5.8 2.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.4 EEB05724.1 - 4.3 7.1 8.5 4.8 7.0 2.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EEB05724.1 - 7.6 6.6 9.7 69 3.4 6.7 1.9 1 1 0 1 1 1 0 DivIVA protein UNC45-central PF11701.3 EEB05725.1 - 4.4e-06 26.4 6.5 0.047 13.3 0.3 4.9 3 2 2 5 5 5 4 Myosin-binding striated muscle assembly central zf-HIT PF04438.11 EEB05727.1 - 3.1e-07 29.9 13.3 6.9e-07 28.7 9.2 1.6 1 0 0 1 1 1 1 HIT zinc finger BCIP PF13862.1 EEB05728.1 - 7.5e-60 201.7 0.2 9e-60 201.5 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein tRNA_int_end_N2 PF12928.2 EEB05729.1 - 9.2e-28 95.5 0.1 2.2e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EEB05729.1 - 0.07 12.6 0.0 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Pet191_N PF10203.4 EEB05730.2 - 2.4e-20 72.3 9.5 2.8e-20 72.0 6.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EEB05730.2 - 0.66 9.7 8.8 3.1 7.6 2.3 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEB05730.2 - 1.2 9.1 7.7 1.9 8.4 1.8 2.3 2 0 0 2 2 2 0 CHCH domain Ndufs5 PF10200.4 EEB05730.2 - 3.7 7.6 5.5 4.2 7.4 0.6 2.0 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UCR_hinge PF02320.11 EEB05730.2 - 5.4 7.0 8.4 0.69 9.8 1.9 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Peptidase_M16 PF00675.15 EEB05731.1 - 2.4e-25 89.0 0.0 4e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEB05731.1 - 2.2e-13 50.2 0.0 5.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain WD40 PF00400.27 EEB05732.1 - 3.8e-10 39.2 15.8 4.7e-05 23.1 0.5 5.8 8 0 0 8 8 8 3 WD domain, G-beta repeat Rad51 PF08423.6 EEB05733.1 - 2.8e-30 105.0 0.0 6.4e-29 100.6 0.0 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEB05733.1 - 1.7e-10 40.6 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEB05733.1 - 1.3e-06 27.6 1.4 3.2e-06 26.4 0.1 2.3 2 1 1 3 3 3 1 KaiC RecA PF00154.16 EEB05733.1 - 5.2e-05 22.4 0.0 0.026 13.6 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_22 PF13401.1 EEB05733.1 - 0.01 15.9 0.1 0.072 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EEB05733.1 - 0.042 12.7 0.1 0.26 10.1 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ssl1 PF04056.9 EEB05734.1 - 6.8e-80 267.2 0.1 8.7e-80 266.8 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EEB05734.1 - 2.7e-18 65.7 12.2 2.7e-18 65.7 8.5 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EEB05734.1 - 3.1e-07 30.6 0.0 4.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EEB05734.1 - 0.00033 20.4 9.4 0.00033 20.4 6.5 2.8 3 0 0 3 3 3 2 IBR domain VWA PF00092.23 EEB05734.1 - 0.0091 15.7 0.1 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RanBP PF00641.13 EEB05734.1 - 0.044 12.8 0.2 0.044 12.8 0.2 4.4 5 1 0 5 5 5 0 Zn-finger in Ran binding protein and others PUF PF00806.14 EEB05735.2 - 1.4e-40 134.4 0.2 4.3e-08 32.1 0.0 7.8 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat TryThrA_C PF12319.3 EEB05735.2 - 0.11 11.6 0.3 0.26 10.4 0.2 1.5 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal PTSIIB_sorb PF03830.10 EEB05735.2 - 0.18 11.6 2.5 0.39 10.5 0.3 2.3 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component Mito_carr PF00153.22 EEB05736.1 - 8e-30 102.4 1.6 2.7e-15 55.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Beach PF02138.13 EEB05736.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain MitMem_reg PF13012.1 EEB05737.2 - 1.2e-35 122.0 0.1 2.1e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EEB05737.2 - 1.8e-09 37.3 0.0 5.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Latarcin PF10279.4 EEB05737.2 - 0.094 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Latarcin precursor Choline_transpo PF04515.7 EEB05738.2 - 3e-06 26.2 21.4 3e-06 26.2 14.8 3.2 1 1 1 2 2 2 1 Plasma-membrane choline transporter TCP PF03634.8 EEB05738.2 - 0.084 13.2 0.4 0.14 12.5 0.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor DUF202 PF02656.10 EEB05738.2 - 7.5 6.8 0.0 7.5 6.8 0.0 5.1 3 2 1 4 4 4 0 Domain of unknown function (DUF202) UCH PF00443.24 EEB05739.2 - 5.3e-62 209.3 1.3 6.5e-62 209.0 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB05739.2 - 4.6e-26 91.9 0.6 6.3e-26 91.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CCP_MauG PF03150.9 EEB05739.2 - 0.051 13.8 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase Peptidase_C98 PF15499.1 EEB05739.2 - 0.057 12.7 3.0 3.6 6.7 0.0 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Imm28 PF15574.1 EEB05739.2 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 28 Ribosomal_L19e PF01280.15 EEB05740.1 - 2.9e-62 208.7 9.8 2.9e-62 208.7 6.8 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e AAA PF00004.24 EEB05741.1 - 6.8e-44 149.2 0.0 1.1e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB05741.1 - 7e-07 29.4 0.0 6e-05 23.1 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EEB05741.1 - 1.2e-06 28.2 0.3 2.3e-05 24.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEB05741.1 - 2.6e-06 26.6 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEB05741.1 - 1e-05 25.7 0.0 0.0021 18.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EEB05741.1 - 6.5e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EEB05741.1 - 7.5e-05 23.5 0.3 0.00021 22.1 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EEB05741.1 - 0.00033 20.3 0.1 0.00072 19.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEB05741.1 - 0.00076 19.7 0.2 0.0031 17.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEB05741.1 - 0.00082 18.1 0.0 0.0015 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EEB05741.1 - 0.00096 18.1 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EEB05741.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEB05741.1 - 0.0018 17.4 0.0 0.0044 16.2 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEB05741.1 - 0.0034 16.9 0.3 0.0071 15.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEB05741.1 - 0.0042 16.5 0.1 0.0079 15.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EEB05741.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEB05741.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEB05741.1 - 0.0081 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EEB05741.1 - 0.0089 15.4 0.2 0.069 12.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EEB05741.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EEB05741.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EEB05741.1 - 0.028 13.5 0.1 0.15 11.1 0.0 2.2 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.7 EEB05741.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EEB05741.1 - 0.04 13.6 0.0 0.58 9.8 0.0 2.4 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EEB05741.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.8 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 EEB05741.1 - 0.049 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EEB05741.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EEB05741.1 - 0.078 12.4 0.0 0.29 10.5 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EEB05741.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EEB05741.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PRA1 PF03208.14 EEB05742.1 - 1.3e-29 102.4 3.5 1.6e-29 102.2 2.4 1.0 1 0 0 1 1 1 1 PRA1 family protein Cnd2 PF05786.9 EEB05743.1 - 1.9e-154 516.0 12.6 2.4e-154 515.6 8.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 N-SET PF11764.3 EEB05744.1 - 1.7e-32 112.6 2.2 1.7e-32 112.6 1.5 3.8 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EEB05744.1 - 7.2e-24 84.9 0.3 7.2e-24 84.9 0.2 4.0 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 EEB05744.1 - 1e-18 66.3 2.7 5.2e-18 64.1 1.9 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_6 PF14259.1 EEB05744.1 - 2.1e-10 40.4 0.0 4.8e-06 26.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB05744.1 - 2.7e-10 39.7 0.0 4.7e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05744.1 - 0.0097 15.7 0.2 2.7 7.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) INSIG PF07281.7 EEB05745.1 - 1.4e-27 96.3 6.2 2e-27 95.7 4.3 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) FtsX PF02687.16 EEB05745.1 - 6.3 6.5 10.7 12 5.6 2.7 2.3 2 0 0 2 2 2 0 FtsX-like permease family ATP-synt_S1 PF05827.7 EEB05746.2 - 4.8e-19 68.7 3.2 3.4e-18 65.9 2.2 1.9 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Avl9 PF09794.4 EEB05746.2 - 0.11 10.9 0.2 0.18 10.2 0.1 1.2 1 0 0 1 1 1 0 Transport protein Avl9 Fcf1 PF04900.7 EEB05747.1 - 4.6e-38 129.3 0.9 9e-38 128.4 0.6 1.5 1 0 0 1 1 1 1 Fcf1 Kinesin PF00225.18 EEB05748.2 - 1.1e-109 366.1 0.3 1.1e-109 366.1 0.2 3.1 3 1 0 3 3 3 2 Kinesin motor domain bZIP_1 PF00170.16 EEB05748.2 - 0.00073 19.4 3.1 0.00073 19.4 2.2 6.0 6 1 0 6 6 6 1 bZIP transcription factor Tropomyosin_1 PF12718.2 EEB05748.2 - 0.00098 18.9 23.6 0.00098 18.9 16.4 4.6 4 1 1 5 5 5 1 Tropomyosin like FUSC PF04632.7 EEB05748.2 - 3 6.1 9.0 0.35 9.2 1.0 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF812 PF05667.6 EEB05748.2 - 8 4.8 51.9 1.5 7.2 19.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Abhydrolase_5 PF12695.2 EEB05749.1 - 6.5e-20 71.3 0.0 9.9e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB05749.1 - 3.1e-15 56.6 0.0 1.9e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEB05749.1 - 1.1e-08 33.9 0.3 0.0005 18.6 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EEB05749.1 - 2.8e-08 33.5 0.1 3.8e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 EEB05749.1 - 8.5e-07 28.8 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 EEB05749.1 - 4.9e-05 22.2 0.0 7.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 EEB05749.1 - 0.00013 21.2 0.0 0.0012 18.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EEB05749.1 - 0.0014 17.9 0.0 0.017 14.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EEB05749.1 - 0.0076 15.7 0.1 2.2 7.6 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EEB05749.1 - 0.012 15.1 0.0 0.076 12.4 0.0 2.0 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 EEB05749.1 - 0.024 14.2 0.0 0.069 12.7 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 EEB05749.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EEB05749.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C48 PF02902.14 EEB05750.1 - 4e-24 85.4 0.0 9.6e-24 84.1 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vfa1 PF08432.5 EEB05751.1 - 5.4e-34 117.8 4.9 7.5e-34 117.3 3.4 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 ORC6 PF05460.8 EEB05751.1 - 0.021 13.9 4.5 0.024 13.7 3.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1510 PF07423.6 EEB05751.1 - 0.045 13.1 10.7 0.054 12.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EEB05751.1 - 0.15 10.0 4.1 0.16 9.9 2.8 1.0 1 0 0 1 1 1 0 CDC45-like protein NESP55 PF06390.7 EEB05751.1 - 0.87 8.9 8.3 1.3 8.3 5.8 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Proteasome PF00227.21 EEB05752.1 - 1.7e-49 167.6 0.0 2.1e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB05752.1 - 1.5e-09 36.9 0.4 3.6e-09 35.7 0.3 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADK PF00406.17 EEB05753.2 - 8e-44 149.1 0.1 9.4e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EEB05753.2 - 3.9e-09 36.8 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB05753.2 - 6.9e-07 30.1 0.1 8.6e-07 29.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EEB05753.2 - 8.7e-07 28.4 0.4 0.0009 18.6 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EEB05753.2 - 4.8e-05 23.2 0.0 7.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EEB05753.2 - 0.0032 16.9 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EEB05753.2 - 0.1 12.5 0.2 0.38 10.7 0.0 2.0 1 1 0 2 2 2 0 AAA domain Ribosomal_L13 PF00572.13 EEB05755.1 - 0.00054 20.0 0.5 2.1 8.4 0.0 2.9 1 1 2 3 3 3 2 Ribosomal protein L13 DUF2057 PF09829.4 EEB05755.1 - 0.019 14.6 3.1 35 3.9 2.2 3.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Ferritin PF00210.19 EEB05755.1 - 0.047 13.4 0.7 0.51 10.0 0.1 2.8 4 0 0 4 4 4 0 Ferritin-like domain Transposase_1 PF01359.13 EEB05755.1 - 0.13 12.0 15.5 12 5.7 0.2 4.2 1 1 2 4 4 4 0 Transposase (partial DDE domain) Death PF00531.17 EEB05755.1 - 0.16 11.7 10.9 9.1 6.1 0.3 3.9 1 1 3 4 4 4 0 Death domain IPPT PF01715.12 EEB05755.1 - 0.21 10.5 1.3 16 4.3 0.0 3.5 4 0 0 4 4 4 0 IPP transferase COesterase PF00135.23 EEB05755.1 - 0.43 9.2 2.7 7.4 5.1 0.1 2.1 1 1 1 2 2 2 0 Carboxylesterase family DUF346 PF03984.8 EEB05755.1 - 0.52 9.8 8.3 67 3.0 0.1 4.2 4 0 0 4 4 4 0 Repeat of unknown function (DUF346) Med26 PF08711.6 EEB05755.1 - 0.72 9.4 11.2 17 5.0 0.2 3.9 4 0 0 4 4 4 0 TFIIS helical bundle-like domain Misat_Tub_SegII PF10644.4 EEB05755.1 - 0.87 9.6 15.8 20 5.3 0.1 4.2 1 1 3 4 4 4 0 Misato Segment II tubulin-like domain Ribosomal_S13 PF00416.17 EEB05756.2 - 6e-31 107.0 0.0 7.4e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEB05756.2 - 0.00013 20.7 0.0 0.00014 20.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HSA PF07529.8 EEB05757.1 - 1.4e-16 60.0 6.9 1.6e-16 59.8 1.2 3.0 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EEB05757.1 - 8.5e-11 41.7 0.2 2.6e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEB05757.1 - 0.00074 19.5 0.1 0.0019 18.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp PF00026.18 EEB05758.1 - 3e-35 121.9 0.1 4.1e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEB05758.1 - 1.1e-09 38.5 0.0 2.6e-08 34.0 0.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Erv26 PF04148.8 EEB05759.1 - 6.4e-66 221.7 7.6 7.4e-66 221.5 5.3 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 NDUF_B4 PF07225.7 EEB05759.1 - 0.035 13.9 1.4 0.058 13.1 0.6 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Competence PF03772.11 EEB05759.1 - 0.14 11.1 6.4 0.18 10.8 4.4 1.3 1 0 0 1 1 1 0 Competence protein Polysacc_synt_C PF14667.1 EEB05759.1 - 0.52 10.1 8.7 0.31 10.8 2.1 2.6 1 1 2 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF996 PF06195.8 EEB05759.1 - 1 9.3 6.0 2.4 8.1 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF996) DEAD PF00270.24 EEB05760.1 - 4.2e-43 146.7 0.0 1.5e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB05760.1 - 3.1e-27 94.2 0.1 8.1e-27 92.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB05760.1 - 0.01 15.6 0.0 0.035 13.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EEB05760.1 - 0.29 9.4 0.0 0.53 8.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) DUF3989 PF13150.1 EEB05761.1 - 0.16 11.4 0.6 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF3537 PF12056.3 EEB05761.1 - 2.9 6.5 7.5 1.7 7.2 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3537) DUF1675 PF07897.6 EEB05762.1 - 1.2 8.8 6.6 1.4 8.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MDFI PF15316.1 EEB05762.1 - 3.2 7.7 7.2 4.4 7.2 5.0 1.2 1 0 0 1 1 1 0 MyoD family inhibitor HSP70 PF00012.15 EEB05764.1 - 4.1e-264 877.0 12.6 4.7e-264 876.8 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB05764.1 - 3.1e-20 72.0 0.5 4.2e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEB05764.1 - 0.0014 17.7 4.1 0.033 13.3 0.2 3.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EEB05764.1 - 1.8 8.4 12.1 3.4 7.5 0.2 3.7 3 1 0 3 3 3 0 Cell division protein FtsA BSD PF03909.12 EEB05765.2 - 2.3e-16 59.2 1.1 5e-16 58.1 0.1 2.1 2 0 0 2 2 2 1 BSD domain FAA_hydrolase_N PF09298.6 EEB05765.2 - 0.031 14.2 0.4 0.11 12.5 0.2 2.0 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Effector_1 PF04518.7 EEB05765.2 - 2.1 7.2 7.7 0.063 12.2 0.6 1.8 2 0 0 2 2 2 0 Effector from type III secretion system GATA PF00320.22 EEB05766.1 - 3.3e-31 106.3 13.3 1.7e-17 62.4 2.5 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEB05766.1 - 0.14 11.4 8.3 0.13 11.5 1.2 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EEB05766.1 - 0.16 11.9 3.6 1.5 8.8 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 EEB05766.1 - 0.37 10.5 4.4 1.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EEB05766.1 - 0.38 10.6 15.1 0.53 10.1 0.2 3.6 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EEB05766.1 - 2.1 7.9 4.4 9.8 5.8 0.3 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 EEB05766.1 - 8.1 5.7 11.8 0.22 10.7 0.9 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Nuf2 PF03800.9 EEB05767.2 - 8.2e-41 139.3 1.5 8.2e-41 139.3 1.0 2.5 3 1 0 3 3 3 1 Nuf2 family HalX PF08663.5 EEB05767.2 - 0.016 15.1 0.3 0.016 15.1 0.2 4.3 5 0 0 5 5 5 0 HalX domain DUF3391 PF11871.3 EEB05767.2 - 0.038 14.1 1.2 0.038 14.1 0.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) Reo_sigmaC PF04582.7 EEB05767.2 - 0.2 10.8 10.5 0.044 12.9 2.9 2.7 3 1 0 3 3 3 0 Reovirus sigma C capsid protein ATP-synt_G PF04718.10 EEB05767.2 - 2.3 8.9 0.0 2.3 8.9 0.0 3.5 3 1 1 4 4 4 0 Mitochondrial ATP synthase g subunit Baculo_PEP_C PF04513.7 EEB05767.2 - 2.7 7.8 14.0 8.3 6.2 0.1 4.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EEB05767.2 - 8.7 4.8 38.4 0.42 9.2 8.5 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Peptidase_C12 PF01088.16 EEB05768.1 - 6.3e-49 166.0 0.0 7.1e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 BCA_ABC_TP_C PF12399.3 EEB05768.1 - 0.047 13.3 0.2 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Nipped-B_C PF12830.2 EEB05769.2 - 1.9e-46 158.0 3.9 1.9e-46 158.0 2.7 4.3 6 1 0 6 6 6 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EEB05769.2 - 7.2e-07 29.0 10.5 4.5e-06 26.5 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Oligomerisation PF02410.10 EEB05770.1 - 2.3e-06 27.5 0.1 7.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Oligomerisation domain mRNA_stabil PF13929.1 EEB05770.1 - 0.0057 15.6 0.3 0.0092 14.9 0.2 1.3 1 0 0 1 1 1 1 mRNA stabilisation FF PF01846.14 EEB05770.1 - 0.0079 16.1 0.3 0.047 13.6 0.1 2.5 2 0 0 2 2 2 1 FF domain DEAD PF00270.24 EEB05771.1 - 1.6e-47 161.1 0.1 5.8e-46 156.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB05771.1 - 2.1e-21 75.5 0.0 5.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EEB05771.1 - 8e-20 70.4 0.5 8e-20 70.4 0.4 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Ribosomal_L23 PF00276.15 EEB05772.1 - 2.3e-21 75.5 0.2 3.5e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Adap_comp_sub PF00928.16 EEB05773.1 - 1.2e-81 273.7 0.6 1.5e-81 273.3 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEB05773.1 - 1e-06 28.5 1.2 1e-06 28.5 0.9 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain FerA PF08165.6 EEB05773.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 FerA (NUC095) domain Ran-binding PF05508.6 EEB05774.2 - 2.4e-94 315.6 0.3 3e-94 315.3 0.2 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Vps53_N PF04100.7 EEB05774.2 - 0.078 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Copper-fist PF00649.13 EEB05775.1 - 1.2e-17 62.7 3.9 1.2e-17 62.7 2.7 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain Arrestin_C PF02752.17 EEB05776.1 - 8.7e-22 77.6 0.4 5.7e-19 68.5 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEB05776.1 - 5.2e-18 65.2 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EEB05776.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4349 PF14257.1 EEB05777.1 - 0.01 15.0 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3337 PF11816.3 EEB05778.1 - 5.6e-43 147.5 0.2 9.8e-37 127.0 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EEB05778.1 - 2.4e-22 77.9 11.0 7.4e-08 31.9 0.0 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2036 PF09724.4 EEB05779.1 - 3.4e-44 151.3 4.2 4.1e-44 151.0 2.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 EEB05780.1 - 7.8e-27 94.3 0.1 2.4e-26 92.7 0.1 1.9 1 0 0 1 1 1 1 RhoGEF domain PilJ PF13675.1 EEB05780.1 - 0.055 13.7 1.7 7.8 6.8 0.1 3.3 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Proteasome PF00227.21 EEB05781.1 - 9.8e-59 197.8 0.4 1.2e-58 197.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB05781.1 - 3.9e-14 51.6 0.2 6.8e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Dynein_light PF01221.13 EEB05781.1 - 0.037 14.0 0.7 0.11 12.4 0.5 1.8 1 0 0 1 1 1 0 Dynein light chain type 1 FF PF01846.14 EEB05782.1 - 1.8e-17 62.9 3.7 1.8e-13 50.2 0.0 4.1 4 0 0 4 4 4 2 FF domain WW PF00397.21 EEB05782.1 - 1.2e-09 37.8 5.0 1.9e-06 27.5 0.7 2.4 2 0 0 2 2 2 2 WW domain Tht1 PF04163.7 EEB05783.1 - 7.4e-39 133.5 16.1 9.8e-39 133.1 11.1 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein HTH_WhiA PF02650.9 EEB05783.1 - 0.037 14.3 2.8 0.091 13.1 1.2 2.2 1 1 0 1 1 1 0 WhiA C-terminal HTH domain Peptidase_M4 PF01447.13 EEB05783.1 - 0.41 10.7 4.1 0.34 11.0 0.7 2.1 1 1 1 2 2 2 0 Thermolysin metallopeptidase, catalytic domain IF-2B PF01008.12 EEB05783.1 - 1.5 7.7 11.7 3.3 6.6 2.5 2.3 1 1 1 2 2 2 0 Initiation factor 2 subunit family IL6 PF00489.12 EEB05783.1 - 2.9 7.4 17.3 1.9 8.0 0.2 3.2 2 1 0 3 3 3 0 Interleukin-6/G-CSF/MGF family GATase PF00117.23 EEB05784.2 - 9.6e-10 38.2 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pantoate_transf PF02548.10 EEB05785.1 - 1.3e-103 345.7 1.5 1.4e-101 339.0 1.0 2.0 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EEB05785.1 - 1.2e-08 34.4 0.1 2.4e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEMT PF04191.8 EEB05786.2 - 2.3e-29 101.5 1.0 5e-29 100.5 0.7 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF3429 PF11911.3 EEB05786.2 - 0.0057 16.6 1.0 0.053 13.4 0.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3429) DUF973 PF06157.6 EEB05786.2 - 0.028 13.3 0.5 0.036 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) NUC153 PF08159.7 EEB05787.1 - 2.9e-15 55.5 9.2 1e-11 44.2 0.1 4.1 3 0 0 3 3 3 3 NUC153 domain CDC27 PF09507.5 EEB05788.1 - 1.8e-45 155.9 30.3 4.6e-25 88.7 15.5 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Pterin_bind PF00809.17 EEB05789.1 - 9.1e-68 227.7 0.2 3e-66 222.8 0.0 2.3 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EEB05789.1 - 6.4e-38 129.3 0.0 2.3e-37 127.5 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EEB05789.1 - 5.4e-37 126.4 2.1 3.5e-19 69.0 0.5 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase Radical_SAM PF04055.16 EEB05789.1 - 0.075 13.2 0.0 0.71 10.0 0.0 2.6 2 1 0 2 2 2 0 Radical SAM superfamily Anp1 PF03452.9 EEB05790.1 - 1.8e-116 388.0 0.0 2.4e-116 387.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_7N PF13733.1 EEB05790.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 CRF PF00473.12 EEB05790.1 - 4.2 7.5 5.9 22 5.2 2.7 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family DnaJ PF00226.26 EEB05791.1 - 3.3e-17 61.9 0.7 1.1e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain MutS_III PF05192.13 EEB05791.1 - 0.0053 16.5 1.7 0.0092 15.7 1.2 1.4 1 1 0 1 1 1 1 MutS domain III SAP PF02037.22 EEB05792.1 - 3.8e-06 26.2 0.0 8.5e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 EEB05792.1 - 4.5e-05 23.1 18.7 4.5e-05 23.1 12.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB05792.1 - 4.5e-05 23.3 20.4 4.5e-05 23.3 14.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB05792.1 - 0.00014 21.5 17.7 0.00014 21.5 12.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEB05792.1 - 0.00032 20.2 18.9 0.00032 20.2 13.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB05792.1 - 0.00036 20.1 19.5 0.00047 19.7 9.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB05792.1 - 0.0011 18.8 17.0 0.0011 18.8 11.8 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING End3 PF12761.2 EEB05792.1 - 0.0015 18.1 0.1 0.0054 16.4 0.1 1.9 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 PRP21_like_P PF12230.3 EEB05792.1 - 0.011 15.2 0.5 0.011 15.2 0.4 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-Di19 PF05605.7 EEB05792.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.5 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.7 EEB05792.1 - 6.2 6.6 15.9 0.94 9.3 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-rbx1 PF12678.2 EEB05792.1 - 7.4 6.7 18.0 10 6.3 9.1 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger TRAPPC-Trs85 PF12739.2 EEB05793.1 - 7.6e-87 291.6 3.6 9.9e-87 291.2 2.5 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_14 PF13428.1 EEB05793.1 - 0.13 12.9 0.2 0.54 11.0 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat SNAP PF14938.1 EEB05793.1 - 0.18 10.9 1.3 3.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP VHS PF00790.14 EEB05794.1 - 1e-28 99.7 0.7 2.3e-28 98.6 0.5 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EEB05794.1 - 6.5e-17 60.8 0.1 1.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEB05794.1 - 9.3e-17 60.1 0.0 1.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEB05794.1 - 6.6e-14 51.1 0.1 2.7e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EEB05794.1 - 0.011 15.2 3.2 0.011 15.2 2.2 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif RasGEF_N PF00618.15 EEB05794.1 - 0.042 13.9 0.2 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif GAT PF03127.9 EEB05794.1 - 0.075 13.0 5.3 0.034 14.0 1.8 1.9 2 0 0 2 2 2 0 GAT domain Thioredoxin PF00085.15 EEB05795.1 - 8.3e-20 70.4 0.2 1.7e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EEB05795.1 - 1.1e-18 66.9 0.0 5.3e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 EEB05795.1 - 0.00036 20.7 0.0 0.022 14.9 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.11 EEB05795.1 - 0.0031 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.11 EEB05795.1 - 0.0051 15.5 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.1 EEB05795.1 - 0.0054 16.7 0.1 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like GST_N_3 PF13417.1 EEB05795.1 - 0.0072 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 EEB05795.1 - 0.011 15.3 0.2 0.096 12.2 0.3 2.0 2 0 0 2 2 2 0 Thioredoxin TrbC_Ftype PF09673.5 EEB05795.1 - 0.013 15.0 0.1 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_8 PF13905.1 EEB05795.1 - 0.017 15.2 0.1 0.29 11.2 0.0 2.6 2 1 1 3 3 3 0 Thioredoxin-like MSP1_C PF07462.6 EEB05795.1 - 0.018 13.4 1.7 0.023 13.0 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pilus_CpaD PF09476.5 EEB05795.1 - 0.023 14.1 0.3 0.041 13.3 0.2 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Redoxin PF08534.5 EEB05795.1 - 0.023 14.2 0.2 0.32 10.5 0.1 2.5 1 1 0 1 1 1 0 Redoxin DUF2868 PF11067.3 EEB05795.1 - 0.032 13.3 0.4 2.4 7.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) ArsC PF03960.10 EEB05795.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 ArsC family Metallophos PF00149.23 EEB05796.2 - 8.3e-43 146.1 0.2 1.1e-42 145.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3608 PF12257.3 EEB05797.1 - 4.8e-75 252.0 2.3 2e-73 246.7 1.6 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EEB05797.1 - 1.1e-25 89.0 0.1 2.8e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PEMT PF04191.8 EEB05798.1 - 9.9e-58 192.8 14.1 2e-34 117.8 1.3 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase SNARE PF05739.14 EEB05799.1 - 0.018 14.7 4.4 0.15 11.7 0.2 2.9 2 0 0 2 2 2 0 SNARE domain V-SNARE_C PF12352.3 EEB05799.1 - 0.28 11.2 3.3 4.5 7.4 0.3 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Thi4 PF01946.12 EEB05800.1 - 1.1e-102 342.0 0.1 1.4e-102 341.6 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEB05800.1 - 4.5e-09 35.6 2.1 4.5e-06 25.7 1.3 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEB05800.1 - 5.9e-06 26.2 1.2 1.7e-05 24.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEB05800.1 - 1.2e-05 24.4 0.8 4.1e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEB05800.1 - 1.4e-05 24.1 3.3 0.002 17.0 0.9 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EEB05800.1 - 3.5e-05 23.7 1.4 5.6e-05 23.1 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEB05800.1 - 5.9e-05 22.3 0.3 8.3e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEB05800.1 - 0.0017 18.4 0.2 0.0029 17.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEB05800.1 - 0.0019 18.0 1.0 0.019 14.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EEB05800.1 - 0.0053 15.2 0.7 0.011 14.2 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EEB05800.1 - 0.11 11.3 0.6 1.3 7.8 0.1 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A PALP PF00291.20 EEB05802.1 - 1.3e-71 241.4 0.8 1.7e-71 240.9 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EEB05802.1 - 8.4e-41 137.4 0.0 1.3e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PA PF02225.17 EEB05802.1 - 0.022 14.4 0.1 0.075 12.7 0.1 1.9 1 1 0 1 1 1 0 PA domain DPM3 PF08285.6 EEB05803.1 - 2.8e-17 62.3 0.2 3.1e-17 62.2 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1523 PF07509.6 EEB05803.1 - 0.054 12.7 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) YqhR PF11085.3 EEB05803.1 - 0.055 12.9 0.1 0.067 12.7 0.1 1.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR FGE-sulfatase PF03781.11 EEB05804.1 - 1.7e-27 96.4 0.5 3.2e-25 88.9 0.4 3.0 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Methyltransf_33 PF10017.4 EEB05804.1 - 1.5e-23 83.0 2.3 1.6e-23 83.0 0.2 2.1 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent DinB_2 PF12867.2 EEB05804.1 - 4.5e-07 30.2 0.8 1.1e-06 29.0 0.6 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EEB05804.1 - 0.00035 20.8 0.0 0.00069 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEB05804.1 - 0.00086 19.0 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_31 PF13847.1 EEB05804.1 - 0.011 15.3 0.0 0.055 13.0 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.1 EEB05804.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.1 EEB05805.1 - 0.00047 20.0 0.1 3.6 7.6 0.0 5.1 7 0 0 7 7 7 1 PPR repeat family PPR_3 PF13812.1 EEB05805.1 - 0.0076 16.4 0.1 11 6.5 0.0 5.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF4243 PF14027.1 EEB05806.1 - 6.7e-10 38.9 0.0 8.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Mito_carr PF00153.22 EEB05807.1 - 8.1e-58 192.1 0.8 3.9e-23 80.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EEB05807.1 - 0.0025 17.8 0.1 0.17 11.9 0.0 2.8 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Mt_ATP-synt_B PF05405.9 EEB05808.1 - 5.4e-36 123.5 4.0 6.7e-36 123.2 2.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.3 EEB05808.1 - 0.077 12.7 1.4 0.084 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) LAGLIDADG_WhiA PF14527.1 EEB05808.1 - 0.098 12.5 0.3 0.36 10.7 0.1 2.0 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain FliT PF05400.8 EEB05808.1 - 0.45 10.9 9.9 0.065 13.6 3.1 2.3 3 0 0 3 3 3 0 Flagellar protein FliT DUF1664 PF07889.7 EEB05808.1 - 0.66 9.7 4.2 0.25 11.1 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PCP_red PF08369.5 EEB05808.1 - 5.7 6.9 6.8 9.1 6.2 0.1 3.8 2 1 1 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit DUF3437 PF11919.3 EEB05810.2 - 0.0035 16.9 0.0 0.043 13.5 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) CBF PF03914.12 EEB05811.2 - 1.2e-40 138.6 0.8 3.5e-40 137.1 0.1 2.1 2 1 0 2 2 2 1 CBF/Mak21 family PGI PF00342.14 EEB05812.1 - 1.2e-216 719.8 0.0 1.4e-216 719.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Arm PF00514.18 EEB05813.1 - 2.3e-91 296.8 13.8 1.2e-12 47.1 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEB05813.1 - 1e-26 93.0 0.0 4.9e-09 36.3 0.0 5.3 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EEB05813.1 - 8.9e-21 73.7 0.3 1e-07 32.2 0.0 5.9 4 2 2 6 6 6 4 HEAT-like repeat IBB PF01749.15 EEB05813.1 - 2.9e-20 72.2 8.2 5.5e-20 71.3 5.7 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EEB05813.1 - 3.3e-19 67.1 0.3 0.0004 20.2 0.0 7.4 7 0 0 7 7 7 5 HEAT repeat Adaptin_N PF01602.15 EEB05813.1 - 3.9e-07 28.7 0.0 2.2e-05 22.9 0.0 3.0 2 1 1 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.8 EEB05813.1 - 1.8e-06 27.2 0.0 0.0023 17.0 0.0 3.1 1 1 2 3 3 3 2 Armadillo-like CTNNBL PF08216.6 EEB05813.1 - 1e-05 25.0 0.6 1.3 8.6 0.0 5.3 7 0 0 7 7 7 2 Catenin-beta-like, Arm-motif containing nuclear V-ATPase_H_C PF11698.3 EEB05813.1 - 7.2e-05 22.7 0.0 0.068 13.0 0.0 4.3 3 2 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EEB05813.1 - 0.00031 19.1 0.1 0.84 7.8 0.0 3.5 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EEB05813.1 - 0.0071 16.7 0.6 23 5.8 0.0 4.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EEB05813.1 - 0.059 13.1 0.3 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain RNase_T PF00929.19 EEB05814.1 - 3.6e-29 102.1 0.0 6.9e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EEB05814.1 - 0.00021 20.8 0.0 0.0013 18.2 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Med21 PF11221.3 EEB05815.1 - 3.4e-34 117.8 4.5 4.1e-34 117.6 3.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EEB05815.1 - 8.4e-06 25.4 3.5 8.4e-06 25.4 2.4 2.2 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.6 EEB05815.1 - 0.00037 20.2 5.8 0.048 13.5 1.7 2.7 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EEB05815.1 - 0.00045 19.9 7.3 0.0007 19.3 5.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 EEB05815.1 - 0.0031 16.9 6.9 0.0058 16.0 4.8 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.10 EEB05815.1 - 0.0047 16.3 6.3 0.013 14.9 4.3 1.8 1 0 0 1 1 1 1 Septum formation initiator APG6 PF04111.7 EEB05815.1 - 0.0051 15.9 2.8 0.005 15.9 1.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 LUC7 PF03194.10 EEB05815.1 - 0.018 14.5 0.3 0.023 14.2 0.2 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF972 PF06156.8 EEB05815.1 - 0.043 14.1 3.7 0.084 13.2 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 EEB05815.1 - 0.046 14.0 2.4 0.047 14.0 1.7 1.1 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.13 EEB05815.1 - 0.048 13.6 4.0 0.096 12.6 2.4 1.9 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF2205 PF10224.4 EEB05815.1 - 0.061 12.9 3.2 0.098 12.2 1.5 1.9 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CagA PF03507.8 EEB05815.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 CagA exotoxin IncA PF04156.9 EEB05815.1 - 0.093 12.3 7.9 0.048 13.2 4.3 1.4 2 0 0 2 2 2 0 IncA protein FliD_C PF07195.7 EEB05815.1 - 0.15 11.3 2.6 0.17 11.1 1.8 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HAP1_N PF04849.8 EEB05815.1 - 0.2 10.5 9.4 0.27 10.1 6.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF607 PF04678.8 EEB05815.1 - 0.21 11.4 1.3 0.29 11.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Fib_alpha PF08702.5 EEB05815.1 - 0.25 11.4 6.3 0.13 12.3 2.5 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 EEB05815.1 - 0.29 11.1 9.0 0.68 9.9 6.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EEB05815.1 - 0.3 10.9 7.8 0.14 12.0 4.1 1.5 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 EEB05815.1 - 0.3 9.4 1.1 0.36 9.2 0.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YjcZ PF13990.1 EEB05815.1 - 0.36 9.9 3.4 0.19 10.8 1.2 1.4 2 0 0 2 2 2 0 YjcZ-like protein DUF2203 PF09969.4 EEB05815.1 - 0.5 10.6 3.5 0.83 9.8 2.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0449 PF15136.1 EEB05815.1 - 0.51 10.5 4.5 0.24 11.6 1.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 V_ATPase_I PF01496.14 EEB05815.1 - 0.51 8.1 2.3 0.56 7.9 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 EEB05815.1 - 0.67 9.9 8.9 0.86 9.6 4.8 2.2 2 1 0 2 2 1 0 bZIP transcription factor IFT20 PF14931.1 EEB05815.1 - 1.2 9.1 12.8 0.7 9.8 7.4 1.7 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF4404 PF14357.1 EEB05815.1 - 1.4 9.3 7.1 1.1 9.6 3.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4404) XhlA PF10779.4 EEB05815.1 - 1.4 8.8 7.5 2.9 7.8 5.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA NPV_P10 PF05531.7 EEB05815.1 - 1.5 9.0 4.8 23 5.3 3.0 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EEB05815.1 - 4.1 6.2 9.3 9.5 5.0 5.9 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 F1F0-ATPsyn_F PF10791.4 EEB05816.1 - 2.1e-27 95.1 0.4 2.6e-27 94.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EEB05816.1 - 0.00095 19.1 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f DUF2870 PF11069.3 EEB05817.1 - 0.34 10.9 4.1 2.1 8.4 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Ribosomal_L32p PF01783.18 EEB05818.1 - 2.3e-12 46.9 4.3 2.9e-12 46.5 3.0 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 EEB05818.1 - 0.022 14.1 0.2 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 RecR protein zf-C3HC4 PF00097.20 EEB05818.1 - 0.03 13.9 4.1 0.2 11.3 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 EEB05818.1 - 0.042 13.5 1.4 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rad50_zn_hook PF04423.9 EEB05818.1 - 0.077 12.4 1.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_2 PF13923.1 EEB05818.1 - 0.19 11.8 2.7 9.7 6.3 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB05818.1 - 5.3 6.8 6.9 13 5.5 0.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EEB05819.2 - 3.5e-72 242.6 0.0 5.3e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05819.2 - 1e-47 162.3 0.0 1.6e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EEB05819.2 - 1.4e-22 79.8 1.0 5.7e-22 77.8 0.1 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EEB05819.2 - 4.3e-07 29.1 0.0 6.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EEB05819.2 - 0.00023 20.4 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.18 EEB05819.2 - 0.034 13.8 0.0 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB05819.2 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gpi16 PF04113.9 EEB05820.1 - 9.5e-144 479.4 0.4 1.1e-142 475.9 0.3 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component CAF1C_H4-bd PF12265.3 EEB05820.1 - 0.054 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex PPR_2 PF13041.1 EEB05821.1 - 1.1e-33 114.9 14.8 4.1e-11 42.6 0.0 11.9 6 3 8 14 14 14 7 PPR repeat family PPR_3 PF13812.1 EEB05821.1 - 2e-31 105.5 0.9 0.00016 21.6 0.0 12.8 12 1 1 13 13 13 5 Pentatricopeptide repeat domain PPR PF01535.15 EEB05821.1 - 1.9e-28 96.4 12.0 0.0001 22.0 0.0 12.2 13 0 0 13 13 13 6 PPR repeat PPR_1 PF12854.2 EEB05821.1 - 1.4e-16 59.6 13.0 5.2e-07 29.0 0.0 7.6 9 0 0 9 9 8 4 PPR repeat TPR_14 PF13428.1 EEB05821.1 - 5.2e-08 32.8 2.4 4.6 8.1 0.0 8.0 7 3 3 10 10 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05821.1 - 3.1e-06 27.4 1.3 17 5.8 0.0 6.7 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05821.1 - 7.4e-05 22.2 1.8 9 6.3 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05821.1 - 0.00012 21.9 4.8 7.7 6.5 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05821.1 - 0.084 12.8 13.1 43 4.3 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEB05821.1 - 0.24 11.9 1.1 76 4.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05821.1 - 2.1 8.9 11.5 65 4.3 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat G-patch PF01585.18 EEB05822.1 - 2.9e-05 23.7 0.4 7.5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 G-patch domain HIGH_NTase1 PF05636.6 EEB05823.2 - 0.061 12.3 1.0 0.13 11.2 0.1 1.9 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase Snf7 PF03357.16 EEB05824.1 - 2e-22 79.3 4.3 1e-21 77.0 3.6 1.7 2 0 0 2 2 2 1 Snf7 IDEAL PF08858.5 EEB05824.1 - 0.011 15.1 1.2 0.28 10.6 0.2 2.9 2 0 0 2 2 2 0 IDEAL domain Macscav_rec PF03523.8 EEB05824.1 - 0.075 12.8 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Macrophage scavenger receptor Tex_N PF09371.5 EEB05824.1 - 4.5 6.5 8.7 2.4 7.4 0.4 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain TRAPPC-Trs85 PF12739.2 EEB05825.1 - 2.2e-91 306.6 8.3 3.5e-91 305.9 5.7 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Kinesin PF00225.18 EEB05826.1 - 7.2e-95 317.5 2.5 7.2e-95 317.5 1.7 2.0 2 0 0 2 2 2 1 Kinesin motor domain Troponin PF00992.15 EEB05826.1 - 0.014 15.4 5.1 0.032 14.2 3.6 1.5 1 1 0 1 1 1 0 Troponin PRANC PF09372.5 EEB05826.1 - 0.033 14.1 1.1 4.6 7.2 0.2 2.7 2 0 0 2 2 2 0 PRANC domain IncA PF04156.9 EEB05826.1 - 0.89 9.1 8.9 1.6 8.2 6.2 1.4 1 0 0 1 1 1 0 IncA protein CTK3_C PF12350.3 EEB05827.1 - 0.035 14.1 0.3 0.044 13.8 0.2 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus ThiF PF00899.16 EEB05828.2 - 2.4e-49 166.6 0.1 3.2e-31 107.9 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EEB05828.2 - 2.2e-40 137.7 0.3 5e-40 136.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EEB05828.2 - 2.2e-37 126.4 0.1 1.9e-23 81.8 0.1 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEB05828.2 - 2.4e-26 90.8 0.6 1.2e-22 78.9 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EEB05828.2 - 0.014 15.4 0.4 0.52 10.3 0.0 2.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 EEB05828.2 - 0.13 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain RNase_PH PF01138.16 EEB05829.2 - 2.7e-32 111.8 0.1 4.2e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FA_synthesis PF02504.10 EEB05829.2 - 0.11 11.3 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein UQ_con PF00179.21 EEB05830.1 - 2.9e-36 123.9 0.0 3.8e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spc97_Spc98 PF04130.8 EEB05831.1 - 1e-23 83.5 16.1 1.3e-22 79.8 11.2 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF4456 PF14644.1 EEB05831.1 - 0.0052 16.0 0.4 0.012 14.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) SF3b10 PF07189.6 EEB05832.1 - 1.6e-32 111.1 0.0 1.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MCM PF00493.18 EEB05833.1 - 2.3e-138 460.5 1.0 3.8e-138 459.8 0.7 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEB05833.1 - 9.7e-20 71.2 0.0 9.7e-20 71.2 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEB05833.1 - 4.5e-08 32.5 0.0 5.9e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EEB05833.1 - 0.0011 18.4 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EEB05833.1 - 0.0016 18.0 0.0 0.0053 16.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEB05833.1 - 0.0051 16.5 0.1 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.9 EEB05833.1 - 0.025 14.6 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Suf PF05843.9 EEB05835.1 - 1.4e-13 51.2 16.7 0.00047 19.9 0.2 6.4 3 2 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EEB05835.1 - 5.7e-10 39.3 6.8 0.004 17.4 0.1 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05835.1 - 2e-09 37.2 8.2 0.017 15.0 0.0 7.4 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05835.1 - 1.1e-08 34.8 15.7 5.6 7.8 0.0 10.0 9 2 3 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05835.1 - 1.9e-07 31.5 12.4 0.01 16.4 0.0 6.6 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05835.1 - 2.9e-07 30.0 5.8 1.1 8.9 0.0 6.8 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 EEB05835.1 - 6.6e-06 25.6 15.6 1.2 9.2 0.2 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EEB05835.1 - 3.3e-05 23.6 9.8 0.18 11.6 0.1 5.9 6 1 1 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 EEB05835.1 - 0.00036 19.5 13.5 1 8.1 0.0 5.6 3 2 3 6 6 6 3 NRDE-2, necessary for RNA interference TPR_8 PF13181.1 EEB05835.1 - 0.00097 18.7 7.1 1.7 8.5 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat SNAP PF14938.1 EEB05835.1 - 0.0045 16.1 0.1 6.5 5.8 0.0 4.0 3 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP PPR PF01535.15 EEB05835.1 - 0.084 12.8 0.3 1.4 9.0 0.0 3.4 3 0 0 3 3 2 0 PPR repeat PPR_3 PF13812.1 EEB05835.1 - 0.17 12.2 0.4 25 5.4 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 EEB05835.1 - 0.26 11.2 7.5 6.9 6.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05835.1 - 0.72 10.4 10.4 13 6.4 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.17 EEB05836.1 - 1.4e-24 85.7 0.0 2.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1667 PF07892.6 EEB05836.1 - 0.11 12.2 0.2 0.95 9.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1667) TPR_1 PF00515.23 EEB05837.2 - 3.1e-50 165.8 36.7 1.8e-08 33.5 0.1 11.0 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05837.2 - 2.3e-46 155.2 26.6 2.1e-11 43.3 0.2 6.7 3 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 EEB05837.2 - 1.8e-43 142.9 32.1 5.6e-06 25.8 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05837.2 - 7.6e-31 103.5 25.4 6.6e-05 22.4 0.1 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05837.2 - 3.4e-29 100.8 19.3 2.8e-07 31.0 0.5 8.0 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05837.2 - 7.2e-28 96.3 27.6 1.6e-07 31.1 0.2 7.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05837.2 - 7.7e-28 94.3 21.5 0.0042 17.1 0.0 11.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 EEB05837.2 - 1.9e-25 86.9 10.1 0.0023 18.3 0.0 9.9 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05837.2 - 4.2e-19 67.6 17.9 0.039 14.4 0.0 10.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05837.2 - 6.1e-19 68.1 17.8 0.00012 22.2 0.1 7.4 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 EEB05837.2 - 1.3e-18 65.2 12.5 0.044 13.5 0.1 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEB05837.2 - 7.5e-13 48.1 14.9 0.028 14.2 0.3 7.0 2 2 3 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EEB05837.2 - 2.6e-10 40.2 18.0 2.1e-06 27.7 2.0 4.3 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EEB05837.2 - 0.009 14.8 3.5 1.3 7.7 0.0 3.2 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 EEB05837.2 - 0.29 11.0 10.3 17 5.4 0.1 5.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EEB05837.2 - 8.6 6.4 16.4 12 6.0 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat RFC1 PF08519.7 EEB05839.1 - 1e-50 171.4 0.1 9.1e-50 168.4 0.0 2.4 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EEB05839.1 - 1.9e-12 47.1 0.0 3.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEB05839.1 - 5.6e-10 39.5 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB05839.1 - 9.6e-06 25.7 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEB05839.1 - 3.1e-05 22.8 0.0 0.0005 18.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EEB05839.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 2.7 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EEB05839.1 - 0.00099 19.9 0.0 0.0031 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEB05839.1 - 0.0033 17.4 3.4 0.0052 16.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EEB05839.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEB05839.1 - 0.0063 16.1 0.0 0.045 13.4 0.0 2.2 1 1 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 EEB05839.1 - 0.0071 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EEB05839.1 - 0.018 15.3 0.0 0.051 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EEB05839.1 - 0.021 14.3 0.0 7.7 5.9 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.21 EEB05839.1 - 0.038 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EEB05839.1 - 0.038 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 NTPase DNA_pol3_delta PF06144.8 EEB05839.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RabGAP-TBC PF00566.13 EEB05840.1 - 5.4e-41 140.4 1.5 1.6e-40 138.9 1.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EEB05840.1 - 0.0001 21.7 0.0 0.00027 20.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Hist_deacetyl PF00850.14 EEB05840.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Histone deacetylase domain Peptidase_M22 PF00814.20 EEB05841.1 - 3.7e-68 229.9 0.0 4.3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EEB05841.1 - 0.00032 20.2 0.1 0.00076 19.0 0.0 1.6 1 0 0 1 1 1 1 YycC-like protein Biotin_lipoyl PF00364.17 EEB05842.2 - 3.5e-21 74.6 0.5 7.2e-21 73.6 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EEB05842.2 - 1.5e-07 30.9 1.5 0.018 14.7 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.1 EEB05842.2 - 3.8e-06 27.1 4.7 0.0036 17.6 0.5 3.2 2 1 1 3 3 3 2 HlyD family secretion protein E3_binding PF02817.12 EEB05842.2 - 0.00036 20.0 0.0 0.0011 18.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.18 EEB05842.2 - 0.00038 19.7 0.1 0.0042 16.3 0.0 2.1 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HlyD_2 PF12700.2 EEB05842.2 - 0.0007 18.8 1.5 0.007 15.5 0.9 2.2 1 1 1 2 2 2 1 HlyD family secretion protein DUF2457 PF10446.4 EEB05843.1 - 3.8e-18 65.4 9.6 3.8e-18 65.4 6.7 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2457) Daxx PF03344.10 EEB05843.1 - 0.18 10.2 20.8 0.26 9.7 14.4 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EEB05843.1 - 0.34 8.7 20.0 0.49 8.2 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 EEB05843.1 - 1.2 7.3 9.6 1.6 6.8 6.7 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein RRN3 PF05327.6 EEB05843.1 - 1.4 6.8 8.6 2 6.4 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 EEB05843.1 - 2.5 7.2 13.7 4.7 6.3 9.5 1.4 1 0 0 1 1 1 0 NOA36 protein Rxt3 PF08642.5 EEB05844.1 - 1.2e-22 80.3 0.5 5.7e-14 52.3 0.1 2.5 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.14 EEB05844.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.23 EEB05845.1 - 1.1e-72 244.7 0.0 1.5e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEB05845.1 - 5.9e-71 238.3 0.0 1.1e-70 237.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEB05845.1 - 3.7e-12 46.3 0.0 1.1e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEB05845.1 - 2.6e-10 40.1 0.0 5.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EEB05845.1 - 3.1e-10 40.8 0.0 3.2e-09 37.6 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EEB05845.1 - 1e-06 27.6 0.0 2.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEB05845.1 - 0.00087 19.3 0.0 0.0069 16.4 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEB05845.1 - 0.016 15.1 0.4 0.06 13.2 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEB05845.1 - 0.019 13.8 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain YjeF_N PF03853.10 EEB05845.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Condensation PF00668.15 EEB05845.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Condensation domain SMC_N PF02463.14 EEB05847.2 - 1.5e-59 200.9 61.8 4.7e-35 120.8 0.0 5.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEB05847.2 - 4.6e-29 100.8 0.1 2.1e-28 98.6 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEB05847.2 - 1.5e-10 41.5 21.5 1.1e-08 35.3 0.7 4.4 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.1 EEB05847.2 - 9e-06 25.1 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EEB05847.2 - 0.00011 20.8 31.3 0.00011 20.8 21.7 5.6 3 2 2 5 5 5 3 AAA domain ATG16 PF08614.6 EEB05847.2 - 2.5 7.9 115.1 0.049 13.4 8.3 7.1 2 2 3 6 6 6 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EEB05847.2 - 6.8 6.2 136.6 0.038 13.5 16.6 7.5 2 2 5 7 7 7 0 IncA protein LPP PF04728.8 EEB05847.2 - 8.8 6.2 13.7 11 5.8 0.0 5.3 6 0 0 6 6 6 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EEB05847.2 - 8.8 5.3 50.7 0.55 9.3 5.5 6.0 2 2 4 6 6 6 0 Reovirus sigma C capsid protein TAF8_C PF10406.4 EEB05848.2 - 1.6e-19 69.7 1.8 2.8e-19 68.9 1.2 1.4 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Ino80_Iec3 PF14612.1 EEB05849.1 - 2.1e-11 44.3 0.0 2.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sld5 PF05916.6 EEB05850.1 - 4.2e-08 33.4 0.0 6.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkinase PF00069.20 EEB05851.1 - 1.2e-24 86.9 0.0 2.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05851.1 - 1.2e-15 57.3 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2401 PF10287.4 EEB05852.1 - 4.9e-95 317.4 5.0 4.9e-95 317.4 3.5 2.1 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EEB05852.1 - 1.8e-28 98.4 0.1 5.4e-28 96.9 0.1 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) DUF2413 PF10310.4 EEB05852.1 - 2.9 6.5 5.7 4.1 6.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Sulfate_transp PF00916.15 EEB05853.2 - 4.8e-48 163.5 3.7 4.8e-48 163.5 2.6 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EEB05853.2 - 7.4e-12 44.9 0.0 1.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EEB05853.2 - 1.9e-09 36.9 0.3 3.8e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 STAS domain ThiF PF00899.16 EEB05854.1 - 4.6e-36 123.6 0.5 1e-35 122.4 0.1 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EEB05854.1 - 4.9e-22 77.2 0.0 1.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EEB05854.1 - 3.6e-16 58.7 0.0 5.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EEB05854.1 - 7.8e-16 57.1 3.7 2e-15 55.8 1.3 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EEB05854.1 - 0.00018 21.0 1.4 0.0008 18.9 0.0 2.5 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EEB05854.1 - 0.02 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 EEB05855.1 - 1.3e-19 69.2 13.9 8.8e-05 22.2 0.0 9.5 10 0 0 10 10 10 7 WD domain, G-beta repeat Syja_N PF02383.13 EEB05856.1 - 2.1e-85 286.3 0.0 2.6e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain AA_kinase PF00696.23 EEB05857.1 - 2.1e-38 132.2 0.1 3.1e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EEB05857.1 - 4.6e-12 45.1 0.7 1.4e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EEB05857.1 - 1.4e-11 43.7 2.8 3.5e-09 36.0 0.1 3.3 3 0 0 3 3 3 2 ACT domain Pescadillo_N PF06732.6 EEB05858.1 - 5.4e-127 422.8 2.4 5.4e-127 422.8 1.7 2.4 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EEB05858.1 - 9.7e-10 38.4 0.0 4.5e-09 36.3 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cytokin_check_N PF10407.4 EEB05859.1 - 2.8e-16 58.8 0.1 7e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus MCM PF00493.18 EEB05860.1 - 6.2e-138 459.1 0.0 2e-137 457.4 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EEB05860.1 - 3.5e-29 101.7 0.2 1.8e-28 99.4 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEB05860.1 - 9.9e-08 31.3 0.0 9.2e-06 24.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEB05860.1 - 8.7e-07 28.7 0.0 3.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEB05860.1 - 0.009 15.6 0.0 0.043 13.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEB05860.1 - 0.066 12.6 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Ribonuc_red_sm PF00268.16 EEB05861.1 - 3.5e-118 393.6 1.3 4.3e-118 393.4 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TRM PF02005.11 EEB05862.1 - 5.6e-145 482.9 0.0 7.1e-145 482.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EEB05862.1 - 4.5e-05 23.1 0.5 7.8e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DEAD PF00270.24 EEB05863.1 - 1e-13 51.1 0.0 1.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EEB05863.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain YesK PF14150.1 EEB05863.1 - 0.068 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 YesK-like protein ResIII PF04851.10 EEB05863.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 EEB05864.1 - 4.1e-14 51.9 0.0 5.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05864.1 - 1.4e-11 44.2 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05864.1 - 3.6e-06 26.7 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB05864.1 - 0.056 13.2 0.1 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Corona_nucleoca PF00937.13 EEB05864.1 - 2.5 6.9 18.4 1.2 8.0 6.0 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein S4 PF01479.20 EEB05865.1 - 7.7e-11 41.2 0.1 1.5e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EEB05865.1 - 3.2e-05 23.4 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 S4 domain NTP_transferase PF00483.18 EEB05866.2 - 6.9e-26 91.0 0.0 9.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EEB05866.2 - 5.1e-11 41.5 7.5 1.3e-07 30.7 0.8 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEB05866.2 - 5.8e-07 29.7 0.0 1.7e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EEB05866.2 - 0.16 10.5 3.2 0.48 8.9 0.7 2.1 2 0 0 2 2 2 0 L-fucokinase Pex14_N PF04695.8 EEB05867.1 - 1.9e-18 66.7 2.7 1.6e-13 50.8 0.2 3.6 2 2 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3486 PF11985.3 EEB05867.1 - 0.013 15.5 1.6 0.034 14.1 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) ASL_C PF08328.6 EEB05867.1 - 0.017 14.9 1.3 0.52 10.1 0.0 2.7 2 1 1 3 3 3 0 Adenylosuccinate lyase C-terminal DUF1759 PF03564.10 EEB05867.1 - 0.028 14.2 2.9 0.18 11.6 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Hemagglutinin PF00509.13 EEB05867.1 - 0.028 12.5 1.5 0.036 12.2 1.1 1.1 1 0 0 1 1 1 0 Haemagglutinin GTPase_Cys_C PF12631.2 EEB05867.1 - 0.036 14.4 0.8 0.11 12.8 0.5 2.0 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE FUSC PF04632.7 EEB05867.1 - 1.4 7.2 4.3 4.2 5.6 3.0 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.1 EEB05867.1 - 1.8 8.9 11.6 10 6.5 0.6 2.8 1 1 1 2 2 2 0 Snapin/Pallidin Senescence_reg PF04520.8 EEB05867.1 - 2.9 8.3 6.0 5 7.6 4.1 1.6 1 1 0 1 1 1 0 Senescence regulator Baculo_PEP_C PF04513.7 EEB05867.1 - 4.2 7.2 9.7 4.5 7.0 0.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus 2OG-FeII_Oxy_2 PF13532.1 EEB05868.1 - 5.9e-40 137.1 0.0 1e-39 136.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEB05868.1 - 0.037 14.3 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF747 PF05346.6 EEB05869.1 - 2.2e-107 358.9 13.7 3.3e-107 358.4 9.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Complex1_LYR_1 PF13232.1 EEB05870.1 - 5.9e-17 61.6 1.2 9.8e-17 60.9 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEB05870.1 - 9.7e-17 60.5 0.9 1.6e-16 59.8 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EEB05870.1 - 0.097 13.1 0.4 0.12 12.9 0.3 1.2 1 0 0 1 1 1 0 Complex1_LYR-like zf-DHHC PF01529.15 EEB05871.1 - 4.7e-32 110.7 13.0 4.7e-32 110.7 9.0 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase SPRY PF00622.23 EEB05872.1 - 3.6e-11 43.2 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 SPRY domain PHD PF00628.24 EEB05872.1 - 0.0024 17.5 10.7 0.0048 16.5 7.5 1.5 1 0 0 1 1 1 1 PHD-finger Bystin PF05291.6 EEB05873.1 - 8e-134 445.2 0.0 1.2e-133 444.6 0.0 1.2 1 0 0 1 1 1 1 Bystin Presenilin PF01080.12 EEB05873.1 - 2 7.1 3.7 3.9 6.2 2.3 1.6 2 0 0 2 2 2 0 Presenilin Sec62 PF03839.11 EEB05873.1 - 3.3 7.0 7.0 6 6.2 4.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Sec63 PF02889.11 EEB05874.1 - 1.7e-136 454.5 4.6 1.5e-86 290.4 0.4 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEB05874.1 - 3.6e-55 186.0 0.3 4e-28 98.0 0.2 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EEB05874.1 - 7e-18 65.1 0.0 3.6e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEB05874.1 - 9.9e-16 57.3 0.0 1.5e-06 27.9 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB05874.1 - 8.9e-07 29.1 2.0 0.018 15.1 0.0 4.2 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EEB05874.1 - 9e-06 25.3 0.0 0.079 12.7 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_10 PF12846.2 EEB05874.1 - 0.00012 21.6 0.1 1.2 8.5 0.0 4.4 4 0 0 4 4 4 2 AAA-like domain PhoH PF02562.11 EEB05874.1 - 0.0013 17.9 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EEB05874.1 - 0.004 17.3 0.9 0.63 10.2 0.0 3.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEB05874.1 - 0.018 14.1 0.0 1.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.12 EEB05874.1 - 0.027 13.8 0.2 5.7 6.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Longin PF13774.1 EEB05875.1 - 2.7e-20 71.6 0.0 4.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEB05875.1 - 1.6e-14 53.2 0.9 2.4e-14 52.6 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Gb3_synth PF04572.7 EEB05875.1 - 0.12 12.0 0.0 13 5.4 0.0 2.4 1 1 1 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Snf7 PF03357.16 EEB05876.2 - 7.6e-22 77.4 14.3 1e-21 77.0 9.9 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EEB05876.2 - 0.00062 19.2 5.3 0.001 18.5 3.7 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Arc PF03869.9 EEB05876.2 - 0.013 15.1 0.9 0.12 12.0 0.7 2.3 2 0 0 2 2 2 0 Arc-like DNA binding domain DUF2560 PF10834.3 EEB05876.2 - 0.067 13.1 1.0 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) DUF3385 PF11865.3 EEB05876.2 - 0.08 12.8 1.2 0.12 12.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) RP-C_C PF11800.3 EEB05876.2 - 0.64 9.6 7.0 0.13 11.8 1.9 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region YlqD PF11068.3 EEB05876.2 - 1.4 8.9 9.1 0.73 9.8 3.8 2.1 1 1 1 2 2 2 0 YlqD protein Adaptin_binding PF10199.4 EEB05876.2 - 2 8.7 6.7 0.36 11.1 1.5 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Tfb2 PF03849.9 EEB05877.1 - 1.8e-145 484.1 0.1 2.7e-145 483.6 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEB05877.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EEB05877.1 - 0.058 12.8 0.0 0.23 10.9 0.0 2.1 1 0 0 1 1 1 0 Anti-repressor SinI 4HBT PF03061.17 EEB05878.1 - 3.7e-12 46.1 0.1 5.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EEB05878.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ChaC PF04752.7 EEB05879.1 - 2.4e-57 193.7 0.0 3e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein FliL PF03748.9 EEB05879.1 - 0.083 12.8 0.4 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Med17 PF10156.4 EEB05880.1 - 5e-62 209.7 0.8 6.2e-62 209.3 0.6 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF4131 PF13567.1 EEB05881.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AF1Q PF15017.1 EEB05881.1 - 0.16 11.8 3.0 0.32 10.9 2.1 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Arf PF00025.16 EEB05882.1 - 5.6e-67 224.3 0.0 6.3e-67 224.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEB05882.1 - 8e-11 41.2 0.1 1.4e-07 30.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEB05882.1 - 4.1e-09 35.9 0.0 4.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEB05882.1 - 2.2e-06 27.5 0.0 7.7e-06 25.8 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EEB05882.1 - 1.7e-05 24.2 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB05882.1 - 0.00013 22.4 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EEB05882.1 - 0.00021 20.5 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEB05882.1 - 0.025 14.0 0.0 0.1 12.0 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EEB05882.1 - 0.028 13.8 0.0 1.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EEB05882.1 - 0.13 11.7 0.0 13 5.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VHS PF00790.14 EEB05883.1 - 4.1e-27 94.5 0.0 1.9e-26 92.4 0.0 2.0 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 EEB05883.1 - 5.3e-11 42.3 0.7 1.9e-10 40.6 0.3 2.0 1 1 0 2 2 2 1 GAT domain Med10 PF09748.4 EEB05885.1 - 3e-28 98.1 0.0 3.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3322 PF11795.3 EEB05885.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) IBD PF10416.4 EEB05885.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD zf-MYND PF01753.13 EEB05886.1 - 9.6e-07 28.5 21.8 1.9e-06 27.5 15.1 1.6 1 1 0 1 1 1 1 MYND finger Arm PF00514.18 EEB05886.1 - 0.058 13.2 0.5 0.32 10.9 0.0 2.5 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat HAT PF02184.11 EEB05887.2 - 7e-21 73.6 59.8 5e-14 51.7 1.3 13.3 12 2 0 12 12 12 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EEB05887.2 - 6.8e-18 63.5 27.2 0.027 15.0 0.4 11.3 6 3 6 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05887.2 - 3.8e-16 59.2 14.0 0.00082 19.9 0.3 7.7 5 2 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.9 EEB05887.2 - 9.7e-16 58.3 22.2 0.0009 19.0 0.1 6.8 5 2 1 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EEB05887.2 - 1.5e-09 38.0 3.5 0.0098 16.2 0.0 7.0 6 2 1 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB05887.2 - 7e-09 34.9 12.0 0.14 12.1 0.0 9.1 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05887.2 - 1.5e-05 24.8 12.7 1.2 9.1 0.1 6.1 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEB05887.2 - 2.1e-05 23.7 15.5 1.5 7.8 0.0 5.9 3 1 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EEB05887.2 - 2.8e-05 24.2 15.3 9.9 6.8 0.0 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEB05887.2 - 0.00019 20.9 10.4 2 8.1 0.0 6.9 6 2 1 7 7 7 1 TPR repeat DUF3987 PF13148.1 EEB05887.2 - 0.0004 19.0 0.4 0.0016 17.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) TPR_7 PF13176.1 EEB05887.2 - 0.00045 19.8 6.0 1.1 9.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB05887.2 - 0.00085 19.3 2.2 0.098 12.9 0.0 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05887.2 - 0.0014 18.2 0.2 3.9 7.4 0.0 4.3 4 0 0 4 4 2 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEB05887.2 - 0.86 8.4 25.5 0.56 9.0 0.9 6.4 2 2 2 6 6 6 0 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.6 EEB05887.2 - 4.1 7.2 18.6 0.14 11.9 0.2 6.3 6 2 2 8 8 7 0 U3 small nucleolar RNA-associated protein 6 PUA PF01472.15 EEB05888.2 - 1.8e-17 62.8 0.2 2.6e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 PUA domain Hira PF07569.6 EEB05889.1 - 5.9e-61 205.4 0.2 9.4e-61 204.8 0.1 1.3 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EEB05889.1 - 1.3e-41 139.0 30.6 8e-11 41.3 0.2 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat HIRA_B PF09453.5 EEB05889.1 - 2.9e-09 36.2 4.1 9.2e-09 34.6 2.9 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EEB05889.1 - 0.00081 18.9 0.2 0.046 13.4 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEB05889.1 - 0.074 10.8 0.2 1.2 6.8 0.1 2.2 1 1 1 2 2 2 0 IKI3 family MGC-24 PF05283.6 EEB05889.1 - 2.8 7.6 10.6 8.2 6.1 7.3 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TPR_2 PF07719.12 EEB05890.1 - 0.0029 17.3 0.1 3.7 7.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF758 PF05527.6 EEB05890.1 - 0.029 13.9 0.1 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF758) PWI PF01480.12 EEB05890.1 - 0.061 13.4 0.1 0.24 11.5 0.1 2.1 1 1 0 1 1 1 0 PWI domain GCOM2 PF15328.1 EEB05890.1 - 0.13 11.9 0.1 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Hydrolase_2 PF07486.7 EEB05890.1 - 0.19 12.2 0.1 0.73 10.3 0.0 1.9 1 0 0 1 1 1 0 Cell Wall Hydrolase TPR_11 PF13414.1 EEB05890.1 - 0.93 9.1 5.4 14 5.3 0.0 4.4 4 0 0 4 4 4 0 TPR repeat ATP-synt_Eps PF04627.8 EEB05891.1 - 5.6e-18 64.2 0.4 7.2e-18 63.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ChAPs PF09295.5 EEB05892.1 - 1.5e-154 514.5 0.0 3.8e-153 509.9 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EEB05892.1 - 4.3e-08 32.6 0.1 0.00065 19.2 0.0 3.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EEB05892.1 - 6.9e-07 28.7 1.2 4.5 7.4 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB05892.1 - 7.7e-07 29.1 0.4 0.0059 16.7 0.4 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEB05892.1 - 1.6e-05 25.0 0.0 5.4 7.9 0.0 6.2 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB05892.1 - 2e-05 24.8 0.1 0.17 12.2 0.0 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB05892.1 - 5e-05 23.8 0.1 0.38 11.4 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB05892.1 - 0.00048 19.7 0.0 0.23 11.3 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEB05892.1 - 0.0033 17.3 0.0 0.17 11.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB05892.1 - 0.0089 15.6 0.5 6.6 6.5 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 EEB05892.1 - 0.054 13.5 0.1 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) UPF0300 PF08594.5 EEB05893.2 - 0.0085 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) DASH_Ask1 PF08655.5 EEB05894.1 - 0.0022 17.7 0.1 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 DASH complex subunit Ask1 PGA2 PF07543.7 EEB05895.1 - 3.1e-35 121.0 0.6 3.4e-35 120.8 0.4 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF2183 PF09949.4 EEB05896.1 - 1.7e-22 79.2 0.0 3.5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) KOW PF00467.24 EEB05897.1 - 1.9e-06 27.3 0.8 1.9e-06 27.3 0.5 2.2 3 1 0 3 3 3 1 KOW motif Gmad1 PF10647.4 EEB05897.1 - 0.081 12.3 0.5 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain OPT PF03169.10 EEB05898.2 - 1.7e-200 667.6 39.8 1.9e-200 667.4 27.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein cobW PF02492.14 EEB05899.1 - 1.5e-43 148.3 0.6 2.3e-43 147.7 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEB05899.1 - 2.1e-05 24.1 0.0 6.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EEB05899.1 - 0.01 15.3 0.1 0.07 12.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EEB05899.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase priB_priC PF07445.7 EEB05899.1 - 0.074 12.5 1.3 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Primosomal replication protein priB and priC UPF0079 PF02367.12 EEB05899.1 - 0.08 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EEB05899.1 - 0.082 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Glycos_transf_4 PF00953.16 EEB05900.1 - 1.1e-32 113.0 12.5 1.1e-32 113.0 8.7 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 Baculo_11_kDa PF06143.6 EEB05900.1 - 0.11 11.8 0.7 0.27 10.6 0.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Hira PF07569.6 EEB05901.1 - 1.4e-65 220.5 0.0 2.3e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EEB05901.1 - 2e-14 52.8 9.0 3.6e-07 29.8 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Zn_clus PF00172.13 EEB05902.2 - 1.3e-08 34.5 10.8 2.1e-08 33.9 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C5HC2 PF02928.11 EEB05902.2 - 0.79 9.8 6.1 3.8 7.6 4.3 1.9 1 1 1 2 2 2 0 C5HC2 zinc finger Kinesin PF00225.18 EEB05905.1 - 3e-69 233.3 0.2 6.4e-69 232.2 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain ISG65-75 PF11727.3 EEB05905.1 - 0.029 13.4 4.7 0.047 12.7 3.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein GTSE1_N PF15259.1 EEB05905.1 - 0.9 9.4 12.9 4.8 7.1 5.0 3.1 2 1 1 3 3 3 0 G-2 and S-phase expressed 1 SlyX PF04102.7 EEB05905.1 - 1 9.8 13.7 0.14 12.5 5.3 2.5 2 0 0 2 2 2 0 SlyX Atg14 PF10186.4 EEB05905.1 - 4.5 6.1 11.3 11 4.8 7.8 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UQ_con PF00179.21 EEB05906.2 - 2.9e-42 143.4 0.0 3.5e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEB05906.2 - 1.1e-09 37.7 0.1 1.6e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Alb1 PF09135.6 EEB05907.1 - 5.5e-06 26.9 3.6 8.3e-06 26.3 2.5 1.3 1 0 0 1 1 1 1 Alb1 Phage_GP20 PF06810.6 EEB05907.1 - 0.097 12.1 3.2 0.12 11.8 2.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 ABC1 PF03109.11 EEB05908.1 - 3.8e-35 120.4 0.0 7.6e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family zf-C2H2 PF00096.21 EEB05909.1 - 2.5 8.6 6.7 0.35 11.2 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type CENP-S PF15630.1 EEB05910.1 - 1.2e-27 95.8 0.2 1.7e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EEB05910.1 - 6.3e-05 23.0 0.1 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EEB05910.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.6 2 1 0 2 2 2 1 Bromodomain associated CENP-T PF15511.1 EEB05910.1 - 0.00039 19.7 0.0 0.00056 19.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EEB05910.1 - 0.0053 16.7 0.6 0.04 13.9 0.0 2.4 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA_11 PF13086.1 EEB05910.1 - 0.057 12.9 0.7 0.09 12.3 0.2 1.5 1 1 1 2 2 2 0 AAA domain TFIID-18kDa PF02269.11 EEB05910.1 - 0.099 12.4 1.0 0.19 11.5 0.3 1.6 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.12 EEB05910.1 - 0.35 10.8 1.6 2.7 8.0 0.1 2.7 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Pept_tRNA_hydro PF01195.14 EEB05911.2 - 1.5e-36 125.6 0.0 3.5e-36 124.4 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Pyridoxal_deC PF00282.14 EEB05912.1 - 4.3e-61 206.4 0.0 5.8e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEB05912.1 - 2.2e-06 26.6 0.0 3.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EEB05912.1 - 0.036 12.6 0.0 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Myosin_head PF00063.16 EEB05913.2 - 6.2e-232 771.5 9.9 9e-232 770.9 6.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EEB05913.2 - 1.3e-20 73.2 6.9 1.9e-20 72.6 0.7 4.0 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 EEB05913.2 - 1.2e-13 49.3 15.8 0.0041 16.6 0.2 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EEB05913.2 - 0.003 17.6 0.0 0.034 14.2 0.0 2.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB05913.2 - 0.4 10.9 3.1 0.84 9.9 0.0 3.0 4 0 0 4 4 4 0 ABC transporter EST1_DNA_bind PF10373.4 EEB05914.2 - 1.5e-21 76.8 17.1 2.9e-21 75.9 6.7 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.4 EEB05914.2 - 1.3e-14 54.3 3.8 1.3e-14 54.3 2.6 2.3 2 0 0 2 2 2 1 Telomerase activating protein Est1 Ribosomal_L22 PF00237.14 EEB05915.1 - 4.4e-34 116.5 0.1 6.9e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e XPC-binding PF09280.6 EEB05916.1 - 5.5e-25 86.6 9.8 1e-24 85.7 6.8 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EEB05916.1 - 2e-22 78.3 1.1 3.5e-22 77.5 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEB05916.1 - 4.5e-21 74.0 4.7 8.7e-10 38.1 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EEB05916.1 - 2.2e-09 36.8 2.8 4e-09 36.0 1.9 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EEB05916.1 - 3.9e-06 26.7 1.1 8.7e-06 25.6 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEB05916.1 - 6.3e-05 23.0 0.2 0.00013 22.0 0.2 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EEB05916.1 - 0.01 15.7 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3135 PF11333.3 EEB05916.1 - 0.025 14.7 0.3 0.24 11.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) UBA_3 PF09288.5 EEB05916.1 - 0.034 13.7 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 EEB05916.1 - 0.036 14.5 0.1 0.15 12.5 0.0 1.9 1 1 1 2 2 2 0 MCM N-terminal domain Pex14_N PF04695.8 EEB05916.1 - 1.4 8.9 9.6 1.2 9.1 1.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.3 EEB05916.1 - 3.5 7.2 13.0 2.1 7.9 1.2 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c NAP PF00956.13 EEB05917.1 - 1.5e-72 243.6 3.1 3.2e-72 242.5 2.1 1.5 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) SecA_SW PF07516.8 EEB05917.1 - 0.054 13.2 0.4 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 SecA Wing and Scaffold domain Fibrillarin PF01269.12 EEB05918.1 - 2.7e-107 356.9 0.0 3.3e-107 356.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EEB05918.1 - 7.8e-07 28.8 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EEB05918.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEB05918.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EEB05918.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Secretin_N PF03958.12 EEB05918.1 - 0.24 11.5 2.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain ECH_C PF13766.1 EEB05919.1 - 1.6e-33 115.3 0.1 3.6e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EEB05919.1 - 5.6e-26 91.1 0.0 1.1e-25 90.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1253 PF06862.7 EEB05920.1 - 2.4e-167 556.8 7.2 3.4e-167 556.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EEB05920.1 - 0.00033 20.1 0.1 0.014 14.9 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase CTP_transf_2 PF01467.21 EEB05921.1 - 1.8e-23 83.3 0.2 3.9e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase AMP-binding PF00501.23 EEB05922.1 - 1.8e-82 276.9 0.0 2.2e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEB05922.1 - 6.8e-16 58.9 0.2 6.8e-16 58.9 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EEB05922.1 - 0.0013 17.3 0.0 0.022 13.3 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Ank_2 PF12796.2 EEB05923.1 - 7.6e-07 29.3 2.3 0.0014 18.9 0.3 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEB05923.1 - 0.0013 18.4 0.1 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Alginate_exp PF13372.1 EEB05923.1 - 0.003 16.2 0.2 0.0091 14.6 0.0 1.8 2 0 0 2 2 2 1 Alginate export Ank_5 PF13857.1 EEB05923.1 - 0.019 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Spore_coat_CotO PF14153.1 EEB05923.1 - 2 7.8 16.8 1 8.7 1.9 2.7 2 0 0 2 2 2 0 Spore coat protein CotO DUF2254 PF10011.4 EEB05923.1 - 4.1 5.7 5.8 1.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) RRM_1 PF00076.17 EEB05924.1 - 5.6e-14 51.5 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB05924.1 - 1.3e-13 50.7 0.0 2.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB05924.1 - 4e-09 36.1 0.1 6.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EEB05925.1 - 2.4e-19 69.8 0.0 2.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EEB05925.1 - 4.7e-19 68.7 0.0 6.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EEB05925.1 - 2e-06 28.4 0.0 2.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain HAD PF12710.2 EEB05926.2 - 3.5e-12 46.8 0.0 6.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB05926.2 - 4e-11 43.7 0.0 6.5e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB05926.2 - 5.9e-08 32.5 0.0 7.7e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEB05926.2 - 0.00047 19.8 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_Coat_B PF05356.6 EEB05926.2 - 0.069 12.8 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Phage Coat protein B Mcp5_PH PF12814.2 EEB05927.1 - 5.8e-08 32.6 0.5 1.6e-06 28.0 0.3 2.9 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 EEB05927.1 - 0.026 14.5 0.2 0.081 13.0 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Ank_4 PF13637.1 EEB05928.1 - 8e-39 131.3 5.2 9.3e-10 38.7 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB05928.1 - 8.3e-33 112.5 1.5 1.4e-18 67.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEB05928.1 - 1.9e-31 107.3 0.7 2.2e-10 40.4 0.1 3.8 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EEB05928.1 - 3.8e-31 105.3 1.6 9.2e-06 25.2 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EEB05928.1 - 5.8e-27 91.0 1.9 0.00028 20.8 0.0 6.3 6 1 0 6 6 6 5 Ankyrin repeat Ribonuc_P_40 PF08584.6 EEB05929.1 - 1.4e-27 96.4 0.0 1.8e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_lig_T4_1 PF09511.5 EEB05930.1 - 2.1e-70 236.6 0.0 3.3e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EEB05930.1 - 2.3e-50 171.1 0.3 3.5e-50 170.6 0.2 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EEB05930.1 - 1.3e-43 148.7 0.0 4.4e-43 147.0 0.0 1.9 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EEB05930.1 - 0.023 15.4 0.0 0.092 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IU_nuc_hydro PF01156.14 EEB05931.2 - 1.6e-95 319.9 0.2 1.8e-95 319.7 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CheY-binding PF09078.6 EEB05931.2 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 CheY binding CBFD_NFYB_HMF PF00808.18 EEB05932.1 - 3e-14 52.7 0.9 6e-14 51.8 0.6 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB05932.1 - 2.6e-06 27.4 0.4 5.6e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SecE PF00584.15 EEB05933.1 - 2.9e-13 49.1 0.0 3.4e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Plectin PF00681.15 EEB05933.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Plectin repeat Con-6 PF10346.4 EEB05934.1 - 8e-31 105.1 2.2 8.9e-15 53.8 0.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 EEB05934.1 - 0.024 14.5 0.3 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Putative toxin 52 Fip1 PF05182.8 EEB05935.1 - 5e-25 86.5 2.5 9e-25 85.6 1.7 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 EEB05936.2 - 3.1e-16 59.6 85.2 1.3e-10 41.4 26.1 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 EEB05936.2 - 0.51 10.1 7.3 0.2 11.4 1.7 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med15 PF09606.5 EEB05936.2 - 0.89 7.6 29.2 1.3 7.1 20.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4404 PF14357.1 EEB05936.2 - 1.7 9.1 5.9 4.6 7.7 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase PF00069.20 EEB05937.1 - 5.5e-56 189.5 0.0 7.8e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05937.1 - 5.2e-22 78.1 0.0 7.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05937.1 - 8.4e-06 24.9 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB05937.1 - 9.1e-05 22.2 0.1 0.073 12.7 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEB05937.1 - 0.0047 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3673 PF12425.3 EEB05937.1 - 0.0081 15.9 0.2 0.028 14.2 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3673) CPSase_L_D2 PF02786.12 EEB05938.1 - 1.8e-113 377.0 0.2 6.5e-84 280.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EEB05938.1 - 4.6e-48 162.0 0.0 1.1e-47 160.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EEB05938.1 - 2.3e-43 147.8 0.0 5.1e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 EEB05938.1 - 5.5e-43 145.5 0.1 1.2e-20 73.6 0.0 3.5 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace_N PF02729.16 EEB05938.1 - 2.4e-40 137.4 0.0 4.9e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EEB05938.1 - 1.2e-39 134.9 0.0 2.2e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 EEB05938.1 - 1.3e-36 125.8 0.0 4.5e-36 124.0 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EEB05938.1 - 1.4e-35 122.6 0.4 1.4e-22 80.3 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEB05938.1 - 6e-22 77.8 0.1 1.4e-10 40.4 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EEB05938.1 - 3.3e-17 62.1 0.0 3e-16 59.1 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EEB05938.1 - 4.8e-16 58.7 0.9 3e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEB05938.1 - 6.4e-15 54.9 0.1 2e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EEB05938.1 - 1.6e-07 31.0 0.1 0.00019 20.9 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EEB05938.1 - 3.2e-05 23.8 0.3 0.26 11.1 0.1 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EEB05938.1 - 6.2e-05 22.5 0.0 0.0044 16.4 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EEB05938.1 - 0.045 13.3 2.4 4.8 6.7 0.0 3.4 5 0 0 5 5 5 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Kri1_C PF12936.2 EEB05939.1 - 1.2e-30 105.3 0.6 1.2e-30 105.3 0.4 3.8 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 EEB05939.1 - 2.1e-26 92.1 16.5 2.1e-26 92.1 11.4 5.3 4 2 2 6 6 6 1 KRI1-like family UCH_1 PF13423.1 EEB05940.2 - 7.7e-72 242.2 1.5 1.4e-71 241.4 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EEB05940.2 - 2.6e-29 102.6 0.0 5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EEB05940.2 - 9.5e-05 21.6 0.3 0.00016 20.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EEB05940.2 - 0.051 13.4 0.0 14 5.7 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat HHA PF05321.6 EEB05941.2 - 0.036 14.2 0.2 0.27 11.4 0.0 2.4 3 0 0 3 3 3 0 Haemolysin expression modulating protein IBN_N PF03810.14 EEB05942.2 - 6.7e-06 25.9 0.3 2.8e-05 23.9 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Peptidase_M24 PF00557.19 EEB05943.1 - 4.5e-40 137.4 0.0 7.5e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEB05943.1 - 5.6e-22 78.6 0.0 7.3e-17 62.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF500 PF04366.7 EEB05944.1 - 7.9e-45 151.3 0.2 1.2e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EEB05944.1 - 2.3e-13 49.3 0.0 4.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB05944.1 - 1.2e-12 47.2 0.0 2.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEB05944.1 - 2.7e-11 42.7 0.0 5.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RAP1 PF07218.6 EEB05944.1 - 1 7.3 3.9 1.4 6.9 2.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vps5 PF09325.5 EEB05945.2 - 8e-11 41.6 4.4 1.2e-10 41.0 3.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEB05945.2 - 4.3e-08 32.9 0.0 9.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF948 PF06103.6 EEB05945.2 - 0.057 13.2 1.4 0.57 10.0 0.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Flavodoxin_1 PF00258.20 EEB05946.2 - 2.2e-33 115.2 0.0 4.4e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EEB05946.2 - 8.5e-30 103.8 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEB05946.2 - 8.5e-19 68.1 0.1 1.9e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EEB05946.2 - 0.011 15.2 0.0 0.4 10.0 0.0 2.6 3 0 0 3 3 3 0 Flavodoxin domain FAD_binding_6 PF00970.19 EEB05946.2 - 0.038 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_5 PF12724.2 EEB05946.2 - 0.041 13.8 0.0 0.49 10.3 0.0 2.5 2 1 1 3 3 3 0 Flavodoxin domain FAD_binding_9 PF08021.6 EEB05946.2 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Cyclin_N PF00134.18 EEB05947.1 - 7.3e-11 41.7 6.2 1.1e-08 34.7 1.7 3.0 2 1 0 2 2 2 2 Cyclin, N-terminal domain GP120 PF00516.13 EEB05947.1 - 0.042 12.0 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Pex24p PF06398.6 EEB05948.1 - 4.8e-05 22.3 3.7 4.8e-05 22.3 2.6 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Peptidase_S10 PF00450.17 EEB05949.2 - 3.5e-71 240.5 0.9 4.9e-71 240.0 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEB05949.2 - 0.0001 22.2 0.4 0.00049 20.0 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family COX5B PF01215.14 EEB05950.2 - 2.3e-40 137.4 0.0 2.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 EEB05950.2 - 0.013 15.3 0.3 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain PGM_PMM_I PF02878.11 EEB05951.1 - 1.1e-12 47.6 0.3 1.8e-05 24.2 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEB05951.1 - 2.1e-11 44.0 0.0 6.5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEB05951.1 - 5.4e-11 42.3 0.1 1.1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EEB05951.1 - 0.018 15.1 0.0 0.13 12.2 0.0 2.4 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III bZIP_1 PF00170.16 EEB05952.2 - 7e-14 51.5 9.9 1.2e-13 50.8 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEB05952.2 - 2.3e-06 27.3 8.9 3.8e-06 26.6 6.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEB05952.2 - 0.0035 17.5 3.6 0.0059 16.8 2.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor SNF2_N PF00176.18 EEB05953.2 - 1.6e-55 188.0 0.3 2.6e-55 187.3 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB05953.2 - 1e-12 47.7 0.0 2.6e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB05953.2 - 6.3e-09 35.9 0.7 1.6e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEB05953.2 - 3.1e-06 26.7 0.2 6.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEB05953.2 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CBM_1 PF00734.13 EEB05954.1 - 2.8e-38 129.2 94.5 2e-12 46.5 7.9 5.2 7 0 0 7 7 7 4 Fungal cellulose binding domain AMP-binding PF00501.23 EEB05955.1 - 3.1e-34 118.0 0.0 6.9e-24 83.9 0.0 4.9 3 2 0 3 3 3 3 AMP-binding enzyme Arf PF00025.16 EEB05956.1 - 2.7e-58 196.0 2.4 3e-58 195.9 1.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEB05956.1 - 4e-15 55.5 0.0 4.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEB05956.1 - 8.3e-12 44.7 0.1 1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EEB05956.1 - 1.1e-11 44.1 5.6 2.8e-07 29.6 0.9 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EEB05956.1 - 2.2e-09 37.2 0.0 3.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEB05956.1 - 6.5e-09 35.4 0.1 8.1e-07 28.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EEB05956.1 - 1.1e-08 35.6 0.0 1.6e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EEB05956.1 - 5e-06 25.8 0.0 6.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EEB05956.1 - 0.0015 18.0 0.2 0.21 11.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EEB05956.1 - 0.002 17.5 0.2 0.37 10.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EEB05956.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEB05956.1 - 0.0038 16.8 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEB05956.1 - 0.0055 16.8 0.0 0.016 15.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EEB05956.1 - 0.0071 15.6 1.8 0.11 11.7 1.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Pox_A32 PF04665.7 EEB05956.1 - 0.015 14.6 0.4 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein CdhD PF03599.11 EEB05956.1 - 0.016 13.7 0.0 0.023 13.1 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Dynamin_N PF00350.18 EEB05956.1 - 0.017 14.9 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EEB05956.1 - 0.035 13.8 0.7 0.14 11.8 0.5 1.9 1 1 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 EEB05956.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EEB05956.1 - 0.094 12.5 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB05956.1 - 0.15 12.3 0.4 0.42 10.9 0.3 1.7 1 1 1 2 2 2 0 AAA domain Septin PF00735.13 EEB05956.1 - 0.23 10.4 1.7 0.46 9.4 0.0 2.1 2 1 0 2 2 2 0 Septin Lon_C PF05362.8 EEB05957.1 - 5.6e-67 225.0 0.0 1.3e-66 223.8 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEB05957.1 - 1.6e-35 122.6 5.6 4.2e-34 118.0 3.9 2.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEB05957.1 - 4.8e-24 85.0 0.0 1.5e-23 83.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEB05957.1 - 1.1e-08 34.9 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EEB05957.1 - 1.6e-07 30.8 0.0 3.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EEB05957.1 - 3.4e-06 27.0 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEB05957.1 - 1.4e-05 25.4 0.4 0.0031 17.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EEB05957.1 - 1.6e-05 25.0 0.1 0.00023 21.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEB05957.1 - 1.9e-05 24.7 0.1 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEB05957.1 - 4.5e-05 24.2 0.0 0.00017 22.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEB05957.1 - 0.00013 21.8 0.0 0.00077 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEB05957.1 - 0.00032 19.8 0.0 0.0012 17.9 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EEB05957.1 - 0.00083 18.1 0.0 0.0014 17.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RNA_helicase PF00910.17 EEB05957.1 - 0.0021 18.1 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EEB05957.1 - 0.0075 15.0 0.2 0.033 12.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EEB05957.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EEB05957.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EEB05957.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase DUF258 PF03193.11 EEB05957.1 - 0.025 13.7 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EEB05957.1 - 0.037 13.7 0.2 0.87 9.2 0.0 2.5 1 1 1 2 2 2 0 NTPase ATP-synt_ab PF00006.20 EEB05957.1 - 0.047 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EEB05957.1 - 0.062 13.6 0.4 0.44 10.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 EEB05957.1 - 0.12 11.5 0.7 8.4 5.4 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEB05957.1 - 0.31 10.7 8.2 3.5 7.2 0.0 3.9 3 2 1 4 4 4 0 Archaeal ATPase Na_trans_assoc PF06512.8 EEB05957.1 - 7.9 6.3 15.4 2.5 7.9 2.9 2.7 3 0 0 3 3 2 0 Sodium ion transport-associated ATP-synt_G PF04718.10 EEB05958.1 - 2.2e-10 41.1 0.1 9.6e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial ATP synthase g subunit DEAD PF00270.24 EEB05959.1 - 9.6e-41 139.0 0.0 4.1e-40 137.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB05959.1 - 3.4e-30 103.7 0.0 9.5e-30 102.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEB05959.1 - 5e-08 32.0 0.0 8.3e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEB05959.1 - 2.6e-07 30.6 2.2 3.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEB05959.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.1 EEB05959.1 - 0.0021 17.7 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEB05959.1 - 0.0047 17.0 0.4 0.037 14.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEB05959.1 - 0.012 14.5 0.1 0.094 11.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Ank PF00023.25 EEB05960.1 - 4.3e-15 54.6 3.9 4.3e-08 32.5 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EEB05960.1 - 9.6e-15 54.6 2.4 1.4e-07 31.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEB05960.1 - 3e-14 52.6 4.8 2.4e-08 33.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB05960.1 - 3e-12 45.5 4.8 3.1e-06 26.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEB05960.1 - 3.4e-12 46.5 4.2 6.3e-07 29.7 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EEB05960.1 - 3.7e-05 23.3 0.5 0.00025 20.6 0.0 2.5 2 2 0 2 2 2 1 KilA-N domain KxDL PF10241.4 EEB05960.1 - 0.02 14.7 0.3 0.02 14.7 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein HH_signal PF01085.13 EEB05960.1 - 0.028 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF2576 PF10845.3 EEB05960.1 - 0.059 12.5 0.2 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) F1F0-ATPsyn_F PF10791.4 EEB05960.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi GCS PF03074.11 EEB05961.1 - 3.3e-164 546.3 0.8 3.6e-164 546.2 0.1 1.4 2 0 0 2 2 2 1 Glutamate-cysteine ligase zf-C2H2_jaz PF12171.3 EEB05962.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB05962.1 - 7.1e-05 22.8 0.2 0.00013 22.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EEB05962.1 - 0.0036 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger Atg14 PF10186.4 EEB05962.1 - 0.1 11.4 2.1 0.12 11.3 1.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S76 PF13611.1 EEB05962.1 - 0.61 10.2 3.1 2.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Serine peptidase of plant viral polyprotein, P1 DUF3505 PF12013.3 EEB05962.1 - 0.91 9.7 3.4 0.77 10.0 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) FliJ PF02050.11 EEB05962.1 - 5.2 7.1 10.8 41 4.2 7.5 2.0 1 1 0 1 1 1 0 Flagellar FliJ protein RGS PF00615.14 EEB05963.1 - 1.3e-16 60.7 0.7 3.5e-16 59.3 0.5 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EEB05963.1 - 7.4e-06 25.6 0.3 0.0036 17.0 0.0 3.4 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Casc1 PF12366.3 EEB05963.1 - 0.0045 16.5 0.3 0.0088 15.5 0.2 1.4 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 Hamartin PF04388.7 EEB05964.1 - 1.9e-57 195.4 11.6 4.1e-57 194.3 7.7 1.7 1 1 0 1 1 1 1 Hamartin protein ERM PF00769.14 EEB05964.1 - 0.2 11.1 32.4 0.73 9.3 13.3 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 EEB05964.1 - 3.1 7.5 16.6 2.3 8.0 1.4 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tho2 PF11262.3 EEB05965.2 - 2.5e-77 259.8 0.2 3.7e-77 259.3 0.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EEB05965.2 - 4.9e-14 51.8 0.4 1.9e-13 50.0 0.1 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Pkinase PF00069.20 EEB05966.1 - 1.1e-59 201.6 0.0 1.4e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05966.1 - 6.3e-38 130.3 0.0 8e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB05966.1 - 1e-08 34.5 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF234 PF03008.9 EEB05967.2 - 0.054 13.6 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function DUF1227 PF06777.6 EEB05968.1 - 2.5e-59 199.1 0.3 5.7e-59 198.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EEB05968.1 - 2.4e-53 180.1 0.0 3.9e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EEB05968.1 - 6.3e-43 146.6 0.0 1.3e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EEB05968.1 - 0.0036 16.8 0.0 1.6 8.1 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EEB05968.1 - 0.023 13.4 0.0 0.17 10.6 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.1 EEB05968.1 - 0.029 13.9 0.0 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EEB05968.1 - 0.045 13.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EEB05969.1 - 1.1e-54 185.3 0.0 1.4e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05969.1 - 3.2e-19 69.0 0.0 6.7e-19 67.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Lactamase_B_2 PF12706.2 EEB05970.1 - 2.4e-31 108.8 0.1 3.7e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEB05970.1 - 4.2e-28 96.5 0.0 9.9e-28 95.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEB05970.1 - 1.5e-08 34.5 0.0 5.1e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2470 PF10615.4 EEB05970.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) Rtf2 PF04641.7 EEB05971.2 - 2.5e-61 207.1 1.4 2.9e-61 206.9 0.9 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EEB05971.2 - 5e-06 25.9 0.1 0.099 12.1 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEB05971.2 - 0.0017 18.0 0.4 0.018 14.7 0.0 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EEB05971.2 - 0.08 12.7 2.2 0.69 9.7 1.8 2.3 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EEB05971.2 - 0.2 11.4 0.8 0.53 10.0 0.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain PTR PF12789.2 EEB05971.2 - 0.53 10.1 7.1 0.79 9.6 3.1 2.5 2 1 0 2 2 2 0 Phage tail repeat like CDP-OH_P_transf PF01066.16 EEB05972.1 - 7.7e-18 64.6 4.5 7.7e-18 64.6 3.1 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EEB05973.2 - 9.6e-30 103.5 0.0 1.1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB05973.2 - 2.6e-21 75.8 0.0 3.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB05973.2 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB05973.2 - 0.012 14.5 0.2 0.031 13.2 0.1 1.7 1 1 0 1 1 1 0 Kinase-like EXS PF03124.9 EEB05974.1 - 9.8e-55 185.9 17.5 1.1e-54 185.7 12.1 1.0 1 0 0 1 1 1 1 EXS family Cpn60_TCP1 PF00118.19 EEB05975.1 - 1.7e-137 459.0 14.6 2e-137 458.7 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mon1 PF03164.9 EEB05976.1 - 8e-91 304.6 3.2 9.2e-91 304.4 2.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 eIF2A PF08662.6 EEB05976.1 - 0.094 12.4 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A GRASP55_65 PF04495.9 EEB05977.1 - 2.5e-52 176.5 0.0 7.1e-44 149.1 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EEB05977.1 - 0.00027 20.7 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Hep_59 PF07052.6 EEB05978.1 - 9.5e-14 51.6 3.3 9.5e-14 51.6 2.3 3.0 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 THF_DHG_CYH PF00763.18 EEB05978.1 - 0.059 13.4 1.9 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF489 PF04356.7 EEB05978.1 - 0.11 12.1 1.4 0.14 11.7 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF1604 PF07713.8 EEB05978.1 - 3.6 7.4 8.0 0.097 12.4 0.8 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1604) Peptidase_M3 PF01432.15 EEB05979.1 - 2.5e-129 432.3 0.0 3.3e-129 431.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EEB05979.1 - 0.085 12.2 0.4 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 Peptidase M50B-like CwfJ_C_1 PF04677.10 EEB05980.1 - 2.1e-33 114.5 0.0 4.7e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEB05980.1 - 9.7e-26 90.1 1.2 2.8e-25 88.6 0.8 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.18 EEB05980.1 - 2.9e-05 24.4 0.1 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HIT domain Metallophos PF00149.23 EEB05980.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase FKBP_C PF00254.23 EEB05981.1 - 5.4e-27 93.6 0.0 2.2e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIF_alpha PF05793.7 EEB05981.1 - 0.0014 17.1 54.2 0.0019 16.6 37.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 EEB05981.1 - 0.0064 15.7 34.2 0.011 14.9 23.7 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T DUF605 PF04652.11 EEB05981.1 - 0.55 9.5 28.3 0.79 9.0 19.6 1.1 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 EEB05981.1 - 1.4 6.9 51.0 2.1 6.3 35.4 1.2 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.5 EEB05981.1 - 4.5 5.5 9.6 6 5.1 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.2 EEB05981.1 - 4.8 4.7 19.2 6.7 4.2 13.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribophorin_I PF04597.9 EEB05982.1 - 2.5e-105 352.5 0.7 2.8e-105 352.3 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I DUF4247 PF14042.1 EEB05982.1 - 0.095 12.6 0.3 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) Nramp PF01566.13 EEB05983.1 - 6.3e-91 304.8 9.7 6.3e-91 304.8 6.7 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phage_holin_2 PF04550.7 EEB05983.1 - 0.0048 16.9 2.5 0.36 10.9 1.2 2.7 2 0 0 2 2 2 2 Phage holin family 2 HEAT_2 PF13646.1 EEB05984.1 - 8.9e-18 64.3 8.4 0.00015 21.9 0.0 8.0 6 3 2 9 9 8 6 HEAT repeats SF3b1 PF08920.5 EEB05984.1 - 3.8e-16 59.4 5.9 2e-15 57.1 4.1 2.2 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.17 EEB05984.1 - 2e-14 52.3 8.7 0.024 14.6 0.0 10.3 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 EEB05984.1 - 8.1e-12 45.2 5.3 0.32 11.5 0.0 8.1 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEB05984.1 - 2.1e-05 24.7 1.6 6.1 7.2 0.0 5.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EEB05984.1 - 0.00017 21.3 1.4 3.8 7.4 0.0 5.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat NUC173 PF08161.7 EEB05984.1 - 0.00026 20.3 0.4 0.88 8.8 0.0 4.4 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EEB05984.1 - 0.00089 18.6 1.2 1.7 7.9 0.0 3.6 4 0 0 4 4 4 2 CLASP N terminal CRM1_C PF08767.6 EEB05984.1 - 0.0048 15.8 0.2 0.012 14.5 0.1 1.6 1 0 0 1 1 1 1 CRM1 C terminal Dopey_N PF04118.9 EEB05984.1 - 0.011 14.4 0.5 2.3 6.9 0.0 3.7 4 1 0 4 4 4 0 Dopey, N-terminal DUF3385 PF11865.3 EEB05984.1 - 0.016 15.1 0.7 1.9 8.4 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) PWWP PF00855.12 EEB05985.1 - 2.7e-07 30.6 0.0 6.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 PWWP domain DUF226 PF02890.9 EEB05985.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 AAA PF00004.24 EEB05986.1 - 1.2e-14 54.6 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEB05986.1 - 1.7e-13 50.5 0.0 1.6e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EEB05986.1 - 1.6e-12 47.2 0.1 3.8e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EEB05986.1 - 4e-08 32.4 0.0 0.0008 18.2 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEB05986.1 - 7.9e-05 22.8 0.0 0.0013 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEB05986.1 - 8e-05 22.7 0.1 0.0063 16.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEB05986.1 - 8e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEB05986.1 - 8e-05 22.3 0.0 0.00022 20.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EEB05986.1 - 0.0001 22.0 0.0 0.00056 19.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEB05986.1 - 0.00036 20.4 0.0 0.001 18.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EEB05986.1 - 0.00094 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EEB05986.1 - 0.0024 17.0 0.1 0.17 11.0 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EEB05986.1 - 0.0036 16.3 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EEB05986.1 - 0.0061 16.0 0.2 0.032 13.7 0.0 2.1 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EEB05986.1 - 0.011 15.3 0.2 0.025 14.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEB05986.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EEB05986.1 - 0.019 14.5 0.1 0.11 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEB05986.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEB05986.1 - 0.026 14.2 0.1 0.13 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EEB05986.1 - 0.027 13.8 0.3 0.088 12.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEB05986.1 - 0.041 12.6 0.2 8.2 5.1 0.0 2.9 2 1 1 3 3 3 0 SNF2 family N-terminal domain Viral_helicase1 PF01443.13 EEB05986.1 - 0.046 13.2 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 EEB05986.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.24 EEB05986.1 - 0.076 12.5 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EEB05986.1 - 0.081 13.7 0.0 0.16 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEB05986.1 - 0.11 11.8 0.1 1.7 8.0 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EEB05986.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 EEB05987.1 - 9.5e-30 103.6 1.1 9.5e-30 103.6 0.8 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NAD_Gly3P_dh_N PF01210.18 EEB05988.1 - 1.9e-52 177.1 0.0 1.1e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEB05988.1 - 9.6e-51 171.4 0.1 2.1e-50 170.2 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EEB05988.1 - 0.012 15.9 0.0 7.7 7.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Proteasome PF00227.21 EEB05990.1 - 1.2e-46 158.4 0.0 1.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EEB05990.1 - 6.3e-13 47.7 0.0 1.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal KH_1 PF00013.24 EEB05991.1 - 0.015 14.9 0.0 0.078 12.6 0.0 2.2 3 0 0 3 3 3 0 KH domain KH_3 PF13014.1 EEB05991.1 - 0.14 11.8 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 KH domain Actin PF00022.14 EEB05992.1 - 7.4e-128 426.3 0.0 8.4e-128 426.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEB05992.1 - 0.0029 16.2 0.0 0.2 10.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Glyco_hydro_81 PF03639.8 EEB05993.1 - 2.5e-234 779.4 19.0 1.8e-195 650.9 7.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 UQ_con PF00179.21 EEB05994.1 - 3.2e-37 127.0 0.0 3.8e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aminotran_3 PF00202.16 EEB05995.1 - 1e-100 336.8 0.0 1.4e-100 336.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III dTMP_synthase PF02593.9 EEB05995.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase HbrB PF08539.6 EEB05996.1 - 1e-36 126.1 0.5 1.5e-36 125.6 0.3 1.2 1 0 0 1 1 1 1 HbrB-like Glyco_transf_15 PF01793.11 EEB05997.1 - 7.7e-131 435.9 6.5 9.7e-131 435.6 4.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 EEB05998.1 - 2.3e-62 204.7 18.7 1.7e-10 40.3 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 EEB05998.1 - 4.6e-11 42.0 0.4 1.2e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEB05998.1 - 4.6e-11 42.2 3.5 5.4e-11 42.0 0.4 2.4 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EEB05998.1 - 1.1e-08 33.7 6.3 0.00033 18.9 0.2 4.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEB05998.1 - 2.1e-06 27.4 0.3 0.011 15.4 0.0 4.9 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EEB05998.1 - 0.0002 20.2 5.7 2.4 6.8 0.1 5.3 2 2 3 5 5 5 2 Nup133 N terminal like CDtoxinA PF03498.9 EEB05998.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.8 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family HTH_40 PF14493.1 EEB05998.1 - 0.17 12.1 0.1 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.22 EEB05999.1 - 1.9e-52 177.1 0.1 7e-30 104.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEB05999.1 - 6e-40 137.3 37.3 6e-24 84.8 10.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEB05999.1 - 1.5e-13 50.4 3.6 4.7e-05 22.7 0.9 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEB05999.1 - 6.1e-12 46.0 6.7 0.012 15.5 1.2 4.3 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 EEB05999.1 - 8.8e-09 35.9 0.2 1.3e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEB05999.1 - 1.6e-07 30.9 0.3 0.0083 15.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EEB05999.1 - 4.2e-07 29.9 2.3 0.017 15.0 1.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EEB05999.1 - 5.9e-07 28.9 8.3 0.0004 19.8 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEB05999.1 - 6.4e-07 29.5 1.2 0.025 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEB05999.1 - 1.8e-06 28.7 0.0 0.035 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEB05999.1 - 4.4e-06 25.9 0.1 0.006 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EEB05999.1 - 8e-06 25.4 0.0 0.065 12.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEB05999.1 - 9.7e-06 25.4 0.2 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family T2SE PF00437.15 EEB05999.1 - 2.7e-05 23.1 0.1 0.14 11.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EEB05999.1 - 0.00029 20.3 0.4 0.27 10.6 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain Zeta_toxin PF06414.7 EEB05999.1 - 0.00033 19.7 0.3 0.072 12.1 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EEB05999.1 - 0.00083 19.6 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEB05999.1 - 0.0014 18.3 0.9 0.47 10.1 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EEB05999.1 - 0.0014 18.4 7.0 0.019 14.7 0.7 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EEB05999.1 - 0.0021 18.2 1.8 2.4 8.2 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EEB05999.1 - 0.0031 17.7 0.6 1.7 8.8 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEB05999.1 - 0.0032 17.3 0.1 3.3 7.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EEB05999.1 - 0.0036 17.7 1.6 1.2 9.6 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_14 PF13173.1 EEB05999.1 - 0.0078 16.1 0.2 6.4 6.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.9 EEB05999.1 - 0.018 14.7 0.1 3.8 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EEB05999.1 - 0.019 14.1 0.6 3.1 6.8 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 EEB05999.1 - 0.034 13.7 0.4 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EEB05999.1 - 0.052 12.9 0.4 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase Sigma54_activat PF00158.21 EEB05999.1 - 0.064 12.7 0.1 8.7 5.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EEB05999.1 - 0.066 12.6 0.1 6 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EEB05999.1 - 0.076 12.4 0.3 16 4.8 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein ResIII PF04851.10 EEB05999.1 - 0.083 12.7 0.0 9.1 6.0 0.1 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EEB05999.1 - 0.1 12.2 0.1 3.2 7.3 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 EEB05999.1 - 0.14 11.7 0.1 14 5.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 EEB05999.1 - 0.14 10.7 0.0 3 6.3 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF815 PF05673.8 EEB05999.1 - 0.15 10.9 0.2 8.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EEB05999.1 - 0.21 10.1 0.8 7.7 5.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EEB05999.1 - 0.31 10.4 2.3 8.6 5.7 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 EEB05999.1 - 0.36 9.7 0.1 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 EEB05999.1 - 0.56 9.2 0.1 2.1 7.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.11 EEB05999.1 - 3.3 6.7 7.5 7.7 5.5 0.3 3.1 3 0 0 3 3 3 0 AIG1 family AAA_13 PF13166.1 EEB05999.1 - 8.9 4.6 4.6 49 2.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain Translin PF01997.11 EEB06000.1 - 1.7e-36 125.7 0.3 2e-36 125.4 0.2 1.0 1 0 0 1 1 1 1 Translin family Allexi_40kDa PF05549.6 EEB06000.1 - 0.054 12.7 0.6 6.9 5.8 0.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 EEB06000.1 - 0.15 11.2 1.8 0.32 10.1 0.2 1.8 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EEB06000.1 - 0.21 11.4 2.0 2.3 8.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EEB06000.1 - 0.32 11.2 6.0 2.2 8.5 0.2 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EEB06000.1 - 0.35 10.7 2.6 8.4 6.2 1.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EEB06000.1 - 0.45 10.2 3.4 2.9 7.6 1.3 2.2 2 0 0 2 2 2 0 Laminin Domain II KTI12 PF08433.5 EEB06001.1 - 1.9e-93 312.5 0.0 2.1e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EEB06001.1 - 3.9e-06 27.6 0.0 6.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB06001.1 - 6.9e-05 22.7 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB06001.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB06001.1 - 0.053 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec7 PF01369.15 EEB06002.1 - 3.6e-69 232.2 1.1 3.6e-69 232.2 0.7 3.4 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 EEB06002.1 - 1.9e-43 147.7 8.6 1.9e-43 147.7 5.9 4.5 5 2 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEB06002.1 - 9.6e-31 105.1 12.6 1.2e-29 101.6 1.7 5.2 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) La PF05383.12 EEB06003.1 - 1.3e-10 40.9 0.0 2.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 La domain Got1 PF04178.7 EEB06004.1 - 2.5e-23 82.4 16.9 3.5e-23 81.9 11.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF485 PF04341.7 EEB06004.1 - 0.021 14.5 2.5 0.021 14.5 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Hep_core_N PF08290.6 EEB06004.1 - 0.089 12.2 4.2 0.22 11.0 2.9 1.7 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Arteri_Gl PF00951.13 EEB06004.1 - 9.9 5.7 17.3 0.68 9.4 6.9 2.0 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein Alpha-amylase PF00128.19 EEB06005.2 - 2.1e-21 76.6 6.7 1.4e-16 60.8 0.2 3.9 4 1 0 4 4 4 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEB06005.2 - 8.5e-11 41.8 0.1 2.2e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB06005.2 - 4.2e-06 26.2 0.0 8.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EEB06005.2 - 0.00035 21.1 0.7 0.00092 19.7 0.5 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain Alpha-amylase PF00128.19 EEB06006.2 - 1.2e-57 195.7 0.7 1.7e-57 195.2 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEB06006.2 - 1.4e-13 50.6 0.0 3.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sec7_N PF12783.2 EEB06007.2 - 1.7e-32 112.1 0.8 1.7e-32 112.1 0.6 4.1 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEB06007.2 - 8.7e-06 25.1 11.4 0.0044 16.5 0.0 6.1 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) Sugar_tr PF00083.19 EEB06010.1 - 1.1e-39 136.2 13.9 1.7e-39 135.6 9.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB06010.1 - 7.9e-21 74.1 14.2 7.9e-21 74.1 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EEB06011.2 - 2.2e-25 89.4 0.2 2.2e-25 89.4 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB06011.2 - 1.6e-16 60.7 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB06011.2 - 2.8e-08 33.6 0.1 2.8e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEB06011.2 - 0.0001 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family VWA_2 PF13519.1 EEB06011.2 - 0.00077 19.6 0.7 0.0016 18.5 0.5 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain NAD_binding_10 PF13460.1 EEB06011.2 - 0.0015 18.6 0.1 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EEB06011.2 - 0.0042 16.2 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EEB06011.2 - 0.012 14.9 0.1 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 EEB06011.2 - 0.012 15.6 1.2 0.062 13.2 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain ParBc PF02195.13 EEB06011.2 - 0.038 14.0 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 ParB-like nuclease domain 2-Hacid_dh_C PF02826.14 EEB06011.2 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.15 EEB06012.1 - 4.6e-06 26.2 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Vps35 PF03635.12 EEB06013.1 - 1.2e-239 797.4 25.6 1.4e-239 797.2 17.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pkinase PF00069.20 EEB06014.1 - 1.9e-51 174.7 0.1 3.1e-51 174.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06014.1 - 1.1e-20 73.8 1.8 6.7e-20 71.2 0.3 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EEB06014.1 - 0.0018 17.6 0.5 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Dus PF01207.12 EEB06015.1 - 5.1e-69 232.4 0.0 6.5e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EEB06015.1 - 0.0036 16.3 0.0 0.01 14.8 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EEB06015.1 - 0.083 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_3 PF13302.1 EEB06016.2 - 9e-17 61.5 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB06016.2 - 1.8e-07 31.0 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EEB06016.2 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEB06016.2 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEB06016.2 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF2042 PF09743.4 EEB06016.2 - 0.16 11.2 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Ubie_methyltran PF01209.13 EEB06017.1 - 9e-84 280.2 0.0 1.1e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEB06017.1 - 2.2e-13 50.0 0.0 5.9e-13 48.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB06017.1 - 7.4e-11 42.3 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB06017.1 - 4.1e-10 40.0 0.1 7.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB06017.1 - 8.4e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB06017.1 - 1.1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB06017.1 - 1.3e-08 35.4 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB06017.1 - 1.6e-05 24.8 0.0 5.5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEB06017.1 - 0.0042 16.7 0.1 0.037 13.6 0.0 2.4 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EEB06017.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ERCC4 PF02732.10 EEB06018.1 - 4.7e-25 88.0 4.1 7.1e-25 87.4 1.2 2.5 3 1 0 3 3 3 1 ERCC4 domain HHH_8 PF14716.1 EEB06018.1 - 0.0036 17.4 0.0 0.018 15.2 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain MRP-L47 PF06984.8 EEB06019.1 - 6.6e-32 109.2 0.8 1e-31 108.6 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) PHD PF00628.24 EEB06020.1 - 4.9e-08 32.5 11.4 8.6e-08 31.7 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB06020.1 - 0.0035 16.6 12.7 0.02 14.2 8.8 2.2 1 1 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EEB06020.1 - 0.12 11.6 7.9 0.32 10.2 5.5 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Cytochrom_c3_2 PF14537.1 EEB06020.1 - 0.19 12.0 7.1 0.13 12.6 1.6 2.5 1 1 1 2 2 2 0 Cytochrome c3 C1_1 PF00130.17 EEB06020.1 - 5.9 6.6 13.1 0.44 10.3 4.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 EEB06021.1 - 3.3e-67 226.3 0.0 4.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06021.1 - 1.3e-29 103.0 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06021.1 - 1.9e-07 30.3 0.0 3.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EEB06021.1 - 1.7e-05 25.2 0.3 3.6e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EEB06021.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 EEB06022.1 - 5.2e-35 120.8 0.0 9.8e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF605 PF04652.11 EEB06022.1 - 1.2 8.4 7.8 2 7.6 5.4 1.4 1 0 0 1 1 1 0 Vta1 like BHD_3 PF10405.4 EEB06023.1 - 2.8e-30 103.8 0.0 5.9e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EEB06023.1 - 1.6e-23 82.6 0.0 4.3e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EEB06023.1 - 1.2e-18 66.3 0.0 2.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EEB06023.1 - 6.8e-17 61.5 0.1 3.5e-16 59.2 0.1 2.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EEB06023.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2418 PF10332.4 EEB06024.1 - 2.9e-28 98.0 0.5 2.9e-28 98.0 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF3328 PF11807.3 EEB06024.1 - 0.77 9.3 4.9 3.1 7.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) CUE PF02845.11 EEB06025.1 - 2.1e-06 27.0 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain CTDII PF01556.13 EEB06026.1 - 1.1e-28 98.8 0.3 2.4e-22 78.6 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EEB06026.1 - 5.4e-25 86.9 4.8 5.4e-25 86.9 3.3 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEB06026.1 - 2.4e-12 46.6 19.3 4.6e-12 45.8 13.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEB06026.1 - 2.8 7.6 8.4 7 6.3 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family NOT2_3_5 PF04153.13 EEB06027.2 - 4.2e-34 117.3 1.0 7.9e-34 116.4 0.7 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family dCMP_cyt_deam_1 PF00383.17 EEB06028.1 - 1.5e-21 75.9 0.1 2.1e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EEB06028.1 - 0.0012 18.4 0.1 0.003 17.2 0.1 1.7 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EEB06028.1 - 0.045 13.4 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase HD_3 PF13023.1 EEB06029.1 - 1.2e-44 151.9 0.7 1.5e-44 151.6 0.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EEB06029.1 - 3.7e-05 23.7 0.3 7.6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EEB06029.1 - 0.0032 17.2 0.1 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme CysG_dimeriser PF10414.4 EEB06029.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region RIX1 PF08167.7 EEB06030.1 - 6.7e-48 162.4 1.3 6.7e-48 162.4 0.9 2.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Ino80_Iec3 PF14612.1 EEB06030.1 - 8.2 6.4 10.4 27 4.7 6.2 2.1 1 1 1 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling FA_desaturase PF00487.19 EEB06031.1 - 4.9e-25 88.4 11.6 7.1e-25 87.9 8.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EEB06031.1 - 1.3e-18 65.9 0.3 2.2e-18 65.1 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Diphthamide_syn PF01866.12 EEB06032.1 - 4.5e-117 390.6 0.0 5.5e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribonuc_L-PSP PF01042.16 EEB06032.1 - 0.094 12.4 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Endoribonuclease L-PSP SPX PF03105.14 EEB06033.1 - 1.1e-46 159.8 4.0 1.6e-46 159.3 2.8 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EEB06033.1 - 1.5e-27 96.5 32.9 2.1e-27 96.1 22.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EEB06033.1 - 3.5e-17 62.0 36.2 2.3e-16 59.3 9.5 2.2 1 1 1 2 2 2 2 Citrate transporter CENP-B_dimeris PF09026.5 EEB06033.1 - 0.00053 20.1 5.3 0.0011 19.1 3.6 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EEB06033.1 - 0.049 13.2 7.4 0.12 11.9 5.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIA_gamma_N PF02268.11 EEB06033.1 - 0.059 12.9 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain EHN PF06441.7 EEB06033.1 - 0.17 11.8 1.1 0.39 10.6 0.8 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF4611 PF15387.1 EEB06033.1 - 0.17 12.0 5.2 0.52 10.4 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EEB06033.1 - 1.4 8.4 14.7 3 7.3 10.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 EEB06033.1 - 1.9 8.3 12.0 2.9 7.7 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC15 PF15243.1 EEB06033.1 - 2 8.5 11.9 4.5 7.4 8.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CDC37_C PF08564.5 EEB06033.1 - 5 7.0 7.2 0.53 10.1 0.1 2.5 2 0 0 2 2 2 0 Cdc37 C terminal domain NOA36 PF06524.7 EEB06033.1 - 5.4 6.1 8.3 8.3 5.5 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EEB06033.1 - 6.5 7.1 15.6 19 5.6 10.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Saccharop_dh PF03435.13 EEB06034.1 - 3.2e-127 424.6 0.0 4e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEB06034.1 - 2.1e-05 24.6 0.1 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EEB06034.1 - 6.6e-05 22.9 0.1 0.00011 22.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding GFO_IDH_MocA PF01408.17 EEB06034.1 - 0.0055 17.2 0.7 0.015 15.7 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EEB06034.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EEB06034.1 - 0.023 14.6 0.1 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EEB06034.1 - 0.043 14.2 0.2 0.09 13.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EEB06034.1 - 0.052 13.8 0.1 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EEB06034.1 - 0.081 12.8 0.2 0.95 9.3 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase CBFD_NFYB_HMF PF00808.18 EEB06035.1 - 5.7e-16 58.3 0.3 8.5e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB06035.1 - 1.4e-09 37.9 0.1 2.3e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EEB06035.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pyr_redox_3 PF13738.1 EEB06036.2 - 1.5e-05 25.1 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEB06036.2 - 5.5e-05 23.1 0.0 0.00049 20.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB06036.2 - 9.7e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEB06036.2 - 0.0031 17.2 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEB06036.2 - 0.039 12.8 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEB06036.2 - 0.13 11.3 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family RRM_1 PF00076.17 EEB06037.1 - 3.9e-17 61.6 0.0 6.5e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06037.1 - 1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06037.1 - 9e-10 38.2 0.0 2.1e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 EEB06038.1 - 2.8e-05 22.2 13.5 0.072 10.9 3.3 4.4 5 0 0 5 5 5 4 Nuclear pore component Rad21_Rec8_N PF04825.8 EEB06040.1 - 1.8e-29 101.8 0.2 3.6e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEB06040.1 - 1.3e-11 43.4 0.1 3.1e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein F-box-like PF12937.2 EEB06041.1 - 6.7e-08 32.1 0.7 2.4e-07 30.3 0.0 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EEB06041.1 - 7.4e-08 31.8 0.2 7.4e-08 31.8 0.1 2.7 3 0 0 3 3 3 1 F-box domain TPR_11 PF13414.1 EEB06041.1 - 3.4e-05 23.3 1.1 0.00014 21.4 0.2 2.2 1 1 1 2 2 2 2 TPR repeat LRR_6 PF13516.1 EEB06041.1 - 0.0048 16.8 5.9 0.7 10.1 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeat FBD PF08387.5 EEB06041.1 - 0.0087 15.5 1.3 0.029 13.8 0.0 2.6 3 0 0 3 3 3 1 FBD LRR_4 PF12799.2 EEB06041.1 - 0.013 15.1 8.5 0.75 9.4 0.3 5.3 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 EEB06041.1 - 0.019 14.8 2.4 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.28 EEB06041.1 - 0.043 13.8 1.6 27 5.3 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat TPR_1 PF00515.23 EEB06041.1 - 0.046 13.3 3.1 3.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DDOST_48kD PF03345.9 EEB06042.1 - 8.5e-123 410.0 0.0 9.8e-123 409.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PfkB PF00294.19 EEB06043.1 - 2.5e-70 237.0 2.7 3.1e-70 236.6 1.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEB06043.1 - 1.5e-06 27.6 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DEC-1_C PF04626.8 EEB06043.1 - 0.076 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region COG4 PF08318.7 EEB06044.1 - 2.2e-74 250.2 1.4 2.6e-74 249.9 0.0 1.8 2 0 0 2 2 2 1 COG4 transport protein DUF2400 PF09674.5 EEB06044.1 - 0.23 11.0 6.7 0.25 11.0 0.8 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2400) DUF1664 PF07889.7 EEB06044.1 - 4 7.2 9.0 1.3 8.7 3.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Inhibitor_I9 PF05922.11 EEB06045.1 - 2.1e-14 53.8 0.0 2.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Band_7 PF01145.20 EEB06046.1 - 2.4e-22 79.7 0.7 3.1e-22 79.3 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family FbpA PF05833.6 EEB06047.1 - 8.9e-34 116.8 23.6 2.8e-26 92.1 0.0 3.2 2 1 1 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EEB06047.1 - 1.8e-17 63.0 1.1 2.9e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 EEB06047.1 - 2.1e-17 62.7 0.0 8.4e-17 60.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) RQC PF09382.5 EEB06047.1 - 0.0063 16.2 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 RQC domain SIR2 PF02146.12 EEB06048.2 - 2.9e-55 186.7 0.0 4.1e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF3465 PF11948.3 EEB06048.2 - 0.083 12.7 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) ZZ PF00569.12 EEB06048.2 - 0.24 10.9 3.4 0.59 9.7 2.3 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type Lzipper-MIP1 PF14389.1 EEB06049.2 - 0.0021 18.1 1.6 0.0054 16.8 1.1 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Syntaxin_2 PF14523.1 EEB06049.2 - 0.016 15.2 0.4 0.03 14.3 0.3 1.5 1 0 0 1 1 1 0 Syntaxin-like protein BUD22 PF09073.5 EEB06049.2 - 0.087 11.8 13.3 0.12 11.4 9.2 1.2 1 0 0 1 1 1 0 BUD22 DUF3987 PF13148.1 EEB06049.2 - 0.1 11.1 2.9 0.15 10.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF572 PF04502.8 EEB06049.2 - 0.35 10.0 12.4 0.48 9.5 8.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.14 EEB06049.2 - 2.3 8.6 10.6 1.3 9.4 5.6 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAF1D PF15333.1 EEB06049.2 - 2.5 7.8 10.7 0.079 12.7 0.6 2.7 1 1 0 2 2 2 0 TATA box-binding protein-associated factor 1D RP-C_C PF11800.3 EEB06049.2 - 9.7 5.8 10.5 34 4.0 7.4 1.9 1 1 1 2 2 2 0 Replication protein C C-terminal region COX4 PF02936.9 EEB06050.1 - 9.6e-45 151.8 0.0 1.2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 EEB06050.1 - 0.0061 16.6 0.3 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) DUF1289 PF06945.8 EEB06050.1 - 0.027 13.9 0.8 0.072 12.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cation_efflux PF01545.16 EEB06051.2 - 2.1e-74 250.1 0.7 2.5e-74 249.9 0.5 1.0 1 0 0 1 1 1 1 Cation efflux family DUF2663 PF10864.3 EEB06051.2 - 0.011 16.0 0.5 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Anoctamin PF04547.7 EEB06051.2 - 0.051 12.2 0.5 1.4 7.5 0.2 2.4 2 1 0 2 2 2 0 Calcium-activated chloride channel Methyltransf_16 PF10294.4 EEB06052.1 - 1.4e-18 66.9 0.0 2.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEB06052.1 - 2.9e-06 27.8 0.0 9.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB06052.1 - 0.00014 21.6 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB06052.1 - 0.00052 19.6 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB06052.1 - 0.014 15.3 0.4 0.087 12.8 0.3 2.1 1 1 0 1 1 1 0 Methyltransferase domain HpcH_HpaI PF03328.9 EEB06052.1 - 0.066 12.0 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family MTS PF05175.9 EEB06052.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EEB06052.1 - 0.09 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L34e PF01199.13 EEB06053.1 - 2.3e-37 127.1 3.5 2.9e-37 126.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e VTC PF09359.5 EEB06054.1 - 1.4e-101 339.2 1.0 1.6e-101 339.1 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EEB06054.1 - 2.4e-26 93.1 16.1 1.8e-11 44.3 0.0 4.2 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EEB06054.1 - 3.2e-07 30.4 3.5 3.2e-07 30.4 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4328 PF14219.1 EEB06054.1 - 0.19 10.9 0.9 0.3 10.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) LXG PF04740.7 EEB06054.1 - 4.3 7.0 9.7 0.25 11.0 1.5 2.7 3 1 1 4 4 4 0 LXG domain of WXG superfamily Fib_alpha PF08702.5 EEB06054.1 - 6.8 6.7 8.1 4.3 7.4 2.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AIRC PF00731.15 EEB06055.1 - 1.6e-67 225.4 1.4 3.8e-67 224.2 1.0 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EEB06055.1 - 2.9e-63 212.2 0.0 5.4e-63 211.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EEB06055.1 - 7.1e-17 61.7 0.0 1.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEB06055.1 - 6e-07 29.0 0.0 2.6e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EEB06055.1 - 1.3e-06 27.8 0.0 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EEB06055.1 - 1.5e-05 23.9 0.0 4.8e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EEB06055.1 - 2.6e-05 24.1 0.0 7.5e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 EEB06055.1 - 0.0041 16.2 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EEB06055.1 - 0.052 13.7 0.8 21 5.2 0.0 3.1 2 1 0 3 3 3 0 CoA binding domain Mad3_BUB1_I PF08311.7 EEB06056.1 - 3.4e-32 110.8 2.9 7.2e-32 109.8 2.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EEB06056.1 - 6.7e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06056.1 - 4.5e-07 29.2 0.0 7.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EEB06056.1 - 0.025 14.5 0.2 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EEB06058.1 - 3e-69 233.0 0.0 4.5e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06058.1 - 4.1e-31 107.9 0.0 1.1e-30 106.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06058.1 - 9.5e-05 21.4 0.3 0.14 11.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 EEB06058.1 - 0.0043 16.4 0.8 0.02 14.2 0.0 2.2 1 1 1 2 2 2 1 RIO1 family Cloacin PF03515.9 EEB06058.1 - 0.009 15.2 0.3 0.019 14.1 0.2 1.5 1 0 0 1 1 1 1 Colicin-like bacteriocin tRNase domain Kdo PF06293.9 EEB06058.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Act-Frag_cataly PF09192.5 EEB06058.1 - 0.085 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF2413 PF10310.4 EEB06059.1 - 4.8e-81 272.8 8.9 6.2e-81 272.4 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) GCOM2 PF15328.1 EEB06059.1 - 0.035 13.8 7.9 0.76 9.4 5.3 2.4 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 PcfK PF14058.1 EEB06059.1 - 3.8 7.6 11.4 18 5.4 4.6 3.0 3 0 0 3 3 3 0 PcfK-like protein GPI-anchored PF10342.4 EEB06060.1 - 1.1e-12 48.3 0.1 2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_L14 PF00238.14 EEB06061.1 - 1.4e-34 118.5 0.0 1.5e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peptidase_M1 PF01433.15 EEB06062.1 - 6.5e-78 262.5 0.0 8.5e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EEB06062.1 - 4.7e-47 159.2 0.0 7.8e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EEB06062.1 - 3.2e-15 56.2 0.1 5.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EEB06062.1 - 0.079 12.9 0.7 0.32 10.9 0.5 1.9 1 1 0 1 1 1 0 M61 glycyl aminopeptidase UDPGP PF01704.13 EEB06063.1 - 1.2e-192 640.0 0.2 1.5e-192 639.8 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TRP PF06011.7 EEB06064.2 - 1.8e-49 168.5 38.5 8.7e-49 166.2 26.7 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel RTA1 PF04479.8 EEB06067.1 - 5.4e-18 65.3 0.3 5.4e-18 65.3 0.2 1.3 2 0 0 2 2 2 1 RTA1 like protein Sre PF03125.13 EEB06067.1 - 0.021 13.7 4.7 0.029 13.2 0.0 2.0 1 1 1 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor PalH PF08733.5 EEB06067.1 - 0.64 8.7 4.8 2.8 6.6 2.2 2.0 1 1 1 2 2 2 0 PalH/RIM21 AA_permease_2 PF13520.1 EEB06068.1 - 3.7e-51 174.0 55.3 4.5e-51 173.7 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB06068.1 - 1.5e-18 66.4 46.9 2e-18 66.0 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease PHD PF00628.24 EEB06070.1 - 8.5e-16 57.3 24.1 4.4e-10 39.0 5.6 3.2 2 1 1 3 3 3 3 PHD-finger Prok-RING_1 PF14446.1 EEB06070.1 - 4.4 7.1 12.1 2.4 7.9 2.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EEB06070.1 - 5.4 6.4 21.7 0.39 10.0 0.3 4.3 3 1 0 3 3 3 0 PHD-finger C1_1 PF00130.17 EEB06070.1 - 7.4 6.3 20.5 0.11 12.2 1.5 3.0 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF5 PF04855.7 EEB06071.1 - 1.6e-30 106.3 0.1 2.6e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pollen_Ole_e_I PF01190.12 EEB06071.1 - 0.069 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pollen proteins Ole e I like zf-DHHC PF01529.15 EEB06072.2 - 2.2e-31 108.5 15.5 2.2e-31 108.5 10.7 2.4 1 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EEB06072.2 - 1.3e-23 83.1 0.7 1.6e-11 44.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEB06072.2 - 3.6e-19 67.5 10.4 7.9e-09 34.8 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EEB06072.2 - 6e-19 68.0 1.7 2e-08 34.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEB06072.2 - 1.4e-15 56.9 4.9 3.9e-07 30.1 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB06072.2 - 3.1e-11 42.3 7.4 1.8e-05 24.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat HMG_box PF00505.14 EEB06074.1 - 0.063 13.5 2.1 0.12 12.7 0.3 2.2 1 1 1 2 2 2 0 HMG (high mobility group) box RhoGAP PF00620.22 EEB06075.1 - 3.7e-36 124.0 0.0 8.2e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EEB06075.1 - 8.1e-08 32.3 2.0 1.1e-07 31.8 0.2 2.1 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain YqzL PF14006.1 EEB06075.1 - 0.053 13.7 0.2 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 YqzL-like protein ATP-synt_DE PF00401.15 EEB06075.1 - 0.071 13.0 1.3 0.19 11.6 0.9 1.8 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ING PF12998.2 EEB06075.1 - 0.1 12.9 4.7 0.14 12.4 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding KxDL PF10241.4 EEB06075.1 - 0.52 10.2 6.5 0.54 10.1 0.7 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein CMS1 PF14617.1 EEB06076.1 - 1.6e-42 145.3 8.6 1.7e-42 145.2 6.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EEB06076.1 - 3.8e-07 29.7 0.1 7.2e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2404 PF10296.4 EEB06077.1 - 4.5e-25 87.6 0.2 1.3e-24 86.1 0.2 1.9 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) LHH PF14411.1 EEB06077.1 - 0.041 14.0 0.7 0.088 13.0 0.5 1.6 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH SUI1 PF01253.17 EEB06078.1 - 1.2e-29 101.8 0.8 1.5e-29 101.6 0.6 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Sel1 PF08238.7 EEB06079.1 - 2.1e-06 28.1 0.0 0.2 12.3 0.0 3.9 4 0 0 4 4 4 2 Sel1 repeat OGG_N PF07934.7 EEB06080.1 - 2.1e-23 82.5 0.2 3.6e-23 81.7 0.2 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain Ctr PF04145.10 EEB06080.1 - 6e-14 52.3 7.5 1.3e-06 28.4 0.0 2.3 1 1 1 2 2 2 2 Ctr copper transporter family HhH-GPD PF00730.20 EEB06080.1 - 2.4e-11 43.8 0.0 3.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEB06080.1 - 4.5e-05 22.9 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Romo1 PF10247.4 EEB06081.1 - 3.7e-26 91.0 6.6 4.7e-26 90.7 4.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Aha1_N PF09229.6 EEB06082.1 - 1.5e-33 115.5 0.0 2.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEB06082.1 - 1.8e-14 53.9 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein WD40 PF00400.27 EEB06083.1 - 1.7e-25 87.9 7.8 2.6e-09 36.5 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEB06083.1 - 2.4e-18 65.8 0.0 5.9e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DeoRC PF00455.17 EEB06083.1 - 0.0059 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain Nucleoporin_N PF08801.6 EEB06083.1 - 0.077 11.7 0.0 0.79 8.4 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like SRP40_C PF05022.7 EEB06085.1 - 7e-28 96.9 3.6 2.3e-27 95.2 2.5 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 EEB06085.1 - 0.0043 16.7 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 LisH THF_DHG_CYH PF00763.18 EEB06086.1 - 1.3e-15 57.4 0.0 2.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EEB06086.1 - 3.6e-15 55.3 0.1 5.7e-13 48.2 0.0 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EEB06086.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF106 PF01956.11 EEB06087.1 - 3.8e-52 176.1 0.4 5e-52 175.8 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 RELT PF12606.3 EEB06087.1 - 0.061 12.4 1.7 0.12 11.4 1.2 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Ribosomal_60s PF00428.14 EEB06088.1 - 2.2e-26 92.0 19.2 2.6e-26 91.8 13.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EEB06088.1 - 0.4 10.2 3.4 0.51 9.9 2.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3138 PF11336.3 EEB06088.1 - 1.1 7.3 3.3 1.2 7.2 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) E1-E2_ATPase PF00122.15 EEB06089.1 - 2.3e-59 200.2 6.0 2.3e-59 200.2 4.1 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEB06089.1 - 1.6e-24 87.5 0.0 3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB06089.1 - 4.3e-13 49.8 0.0 9.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEB06089.1 - 8.5e-10 37.9 0.0 1.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEB06089.1 - 0.0014 18.2 0.1 0.0032 17.0 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB06089.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Mod_r PF07200.8 EEB06090.1 - 0.0014 18.6 7.0 0.0017 18.2 4.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF1204 PF06721.6 EEB06090.1 - 0.15 11.3 3.7 0.34 10.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) I_LWEQ PF01608.12 EEB06090.1 - 1.9 8.3 5.0 0.9 9.4 1.9 1.6 1 1 0 1 1 1 0 I/LWEQ domain HlyD PF00529.15 EEB06090.1 - 2.5 7.3 9.7 3.2 6.9 6.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein AAA PF00004.24 EEB06091.1 - 4.2e-44 149.9 0.0 1.1e-43 148.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEB06091.1 - 2.1e-08 34.2 0.0 4.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEB06091.1 - 1.3e-07 31.4 0.0 4.4e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEB06091.1 - 1.5e-06 28.2 0.1 8.8e-06 25.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB06091.1 - 6.3e-06 26.3 0.1 0.00037 20.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB06091.1 - 6.2e-05 23.8 0.2 0.00016 22.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEB06091.1 - 8.1e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEB06091.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEB06091.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEB06091.1 - 0.00096 17.9 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEB06091.1 - 0.0011 18.8 0.5 0.0032 17.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EEB06091.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF2072 PF09845.4 EEB06091.1 - 0.0017 18.2 0.8 0.0038 17.1 0.5 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) KaiC PF06745.8 EEB06091.1 - 0.0021 17.1 0.0 0.0058 15.7 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.6 EEB06091.1 - 0.0031 17.1 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEB06091.1 - 0.0035 16.4 0.0 0.0081 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EEB06091.1 - 0.0039 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB06091.1 - 0.0047 17.2 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EEB06091.1 - 0.0069 15.6 0.0 0.094 11.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EEB06091.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEB06091.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEB06091.1 - 0.018 14.6 0.0 0.58 9.8 0.0 2.3 1 1 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EEB06091.1 - 0.019 14.3 0.1 0.1 11.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EEB06091.1 - 0.023 14.1 0.0 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EEB06091.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EEB06091.1 - 0.031 13.2 0.0 0.058 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) V_ATPase_I PF01496.14 EEB06091.1 - 0.033 12.0 0.1 0.05 11.4 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Parvo_NS1 PF01057.12 EEB06091.1 - 0.051 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EEB06091.1 - 0.054 13.5 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEB06091.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATG16 PF08614.6 EEB06091.1 - 0.09 12.5 3.4 0.18 11.5 2.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Blo-t-5 PF11642.3 EEB06091.1 - 0.19 11.4 1.8 4.1 7.1 1.0 2.4 2 0 0 2 2 2 0 Mite allergen Blo t 5 HR1 PF02185.11 EEB06091.1 - 0.33 10.7 4.8 1.6 8.5 3.3 2.1 1 1 0 1 1 1 0 Hr1 repeat V-SNARE PF05008.10 EEB06091.1 - 0.57 10.3 4.4 0.47 10.6 1.3 2.1 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 EEB06091.1 - 0.92 9.0 5.2 0.82 9.2 2.5 1.7 2 0 0 2 2 1 0 Septum formation initiator Ribosomal_S13_N PF08069.7 EEB06092.1 - 3.1e-29 100.5 0.4 7.1e-29 99.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEB06092.1 - 2.1e-24 85.1 0.1 3.2e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 SNARE_assoc PF09335.6 EEB06093.1 - 4.2e-10 39.8 4.4 4.2e-10 39.8 3.0 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein PgaD PF13994.1 EEB06093.1 - 0.0019 17.7 0.2 0.0046 16.4 0.1 1.7 1 1 0 1 1 1 1 PgaD-like protein DUF2207 PF09972.4 EEB06093.1 - 0.13 10.8 0.8 0.91 8.0 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 EEB06093.1 - 2.7 8.2 7.0 29 4.9 4.9 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) NPL4 PF05021.10 EEB06094.2 - 3.5e-102 341.6 0.0 4.9e-102 341.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EEB06094.2 - 6.2e-70 233.5 1.3 1e-69 232.8 0.9 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EEB06094.2 - 2.4e-05 24.5 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PX PF00787.19 EEB06095.1 - 4.7e-19 68.2 0.3 1.3e-18 66.8 0.2 1.7 1 0 0 1 1 1 1 PX domain MutS_II PF05188.12 EEB06095.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 MutS domain II Peptidase_S9 PF00326.16 EEB06096.1 - 2.7e-54 183.6 0.1 4.6e-54 182.8 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEB06096.1 - 5.9e-14 52.0 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB06096.1 - 1.1e-08 35.3 0.1 5.9e-08 32.8 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEB06096.1 - 0.00037 19.0 0.1 0.013 14.0 0.1 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Histidinol_dh PF00815.15 EEB06097.1 - 3.2e-162 539.8 0.7 3.8e-162 539.6 0.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase HNOB PF07700.10 EEB06098.1 - 0.0002 20.9 0.2 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding AAA_13 PF13166.1 EEB06098.1 - 0.024 13.1 12.6 0.028 12.8 8.7 1.1 1 0 0 1 1 1 0 AAA domain GrpE PF01025.14 EEB06098.1 - 0.042 13.3 9.4 0.071 12.6 6.3 1.5 1 1 0 1 1 1 0 GrpE DUF1993 PF09351.5 EEB06098.1 - 0.049 13.5 8.4 0.051 13.4 5.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) tRNA_NucTran2_2 PF13735.1 EEB06098.1 - 0.057 13.2 6.3 0.09 12.5 4.4 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative LUC7 PF03194.10 EEB06098.1 - 0.063 12.7 9.2 0.084 12.3 6.4 1.2 1 0 0 1 1 1 0 LUC7 N_terminus RTBV_P46 PF06216.6 EEB06098.1 - 0.077 11.8 2.8 0.096 11.5 1.9 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 EEB06098.1 - 0.11 12.1 19.2 0.16 11.5 13.3 1.2 1 0 0 1 1 1 0 IncA protein RE_NgoFVII PF09565.5 EEB06098.1 - 0.21 10.4 4.6 0.27 10.1 3.2 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Hemagglutinin PF00509.13 EEB06098.1 - 0.25 9.4 6.9 0.34 8.9 4.8 1.1 1 0 0 1 1 1 0 Haemagglutinin Exonuc_VII_L PF02601.10 EEB06098.1 - 0.26 10.4 15.2 0.34 10.0 10.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRE1 PF08647.6 EEB06098.1 - 0.27 11.2 13.0 0.53 10.2 9.0 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.1 EEB06098.1 - 0.35 9.7 13.2 0.44 9.4 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EEB06098.1 - 0.44 9.5 13.8 0.63 9.0 9.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MAT1 PF06391.8 EEB06098.1 - 0.71 9.4 19.0 0.051 13.1 9.9 1.5 2 0 0 2 2 1 0 CDK-activating kinase assembly factor MAT1 ADIP PF11559.3 EEB06098.1 - 0.75 9.6 23.8 0.056 13.3 13.1 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Peptidase_C6 PF00851.13 EEB06098.1 - 0.78 8.2 8.0 1 7.8 5.6 1.2 1 0 0 1 1 1 0 Helper component proteinase DIT1_PvcA PF05141.7 EEB06098.1 - 0.89 8.8 7.4 0.75 9.0 4.4 1.4 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Death PF00531.17 EEB06098.1 - 0.97 9.2 7.9 0.78 9.5 3.2 2.4 1 1 1 2 2 2 0 Death domain DUF724 PF05266.9 EEB06098.1 - 1.2 8.7 11.0 1.1 8.9 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) UCH PF00443.24 EEB06098.1 - 1.2 8.1 7.4 1.5 7.9 5.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase V_ATPase_I PF01496.14 EEB06098.1 - 1.4 6.6 7.3 1.5 6.6 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1826 PF08856.6 EEB06098.1 - 2 8.1 8.5 0.9 9.2 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1826) Tho2 PF11262.3 EEB06098.1 - 2 7.3 9.5 3 6.7 6.6 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2422 PF10337.4 EEB06098.1 - 2.1 7.0 10.0 2.8 6.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Sec20 PF03908.8 EEB06098.1 - 2.2 8.0 15.6 0.5 10.1 6.1 2.3 1 1 1 2 2 2 0 Sec20 DUF3416 PF11896.3 EEB06098.1 - 2.3 8.1 5.8 1.6 8.6 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) TIP120 PF08623.5 EEB06098.1 - 2.6 7.6 10.8 0.49 9.9 2.6 2.1 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) TMF_DNA_bd PF12329.3 EEB06098.1 - 3 7.7 16.0 0.2 11.4 6.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MbeB_N PF04837.7 EEB06098.1 - 4.1 7.5 13.5 1.1 9.4 3.1 3.2 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF948 PF06103.6 EEB06098.1 - 4.2 7.2 15.8 9.1 6.2 4.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Endotoxin_N PF03945.9 EEB06098.1 - 4.6 6.5 9.7 2.7 7.3 4.3 1.9 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DUF3461 PF11944.3 EEB06098.1 - 7.9 6.3 10.9 3.8 7.3 3.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3461) Atg14 PF10186.4 EEB06098.1 - 8.2 5.2 20.3 1.5 7.6 9.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DFP PF04127.10 EEB06099.1 - 9e-21 74.3 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Cmc1 PF08583.5 EEB06100.1 - 1e-12 47.6 7.2 1.7e-12 46.9 5.0 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEB06100.1 - 0.0018 18.1 3.1 0.54 10.2 0.1 2.6 2 0 0 2 2 2 2 CHCH domain Cys_rich_FGFR PF00839.12 EEB06100.1 - 0.0083 16.0 0.3 0.0083 16.0 0.2 1.7 2 0 0 2 2 2 1 Cysteine rich repeat COX17 PF05051.8 EEB06100.1 - 0.57 10.2 2.9 2.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Ubiq_cyt_C_chap PF03981.7 EEB06101.1 - 5.6e-34 117.0 0.8 7.6e-34 116.5 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.8 EEB06102.1 - 2.2e-54 183.4 0.1 2.9e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family PH_7 PF15408.1 EEB06103.1 - 7.8e-53 176.7 0.0 1.7e-52 175.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Anillin PF08174.6 EEB06103.1 - 4.6e-06 26.7 0.1 1.5e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EEB06103.1 - 0.014 15.6 0.0 0.077 13.2 0.0 2.3 1 1 0 1 1 1 0 PH domain PRCC PF10253.4 EEB06104.1 - 3.4e-23 83.2 6.6 3.4e-23 83.2 4.6 2.6 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Topo_C_assoc PF14370.1 EEB06104.1 - 0.04 13.5 0.0 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 C-terminal topoisomerase domain MatE PF01554.13 EEB06105.1 - 5.5e-57 191.9 29.6 1.3e-29 102.9 8.0 2.5 2 0 0 2 2 2 2 MatE SET PF00856.23 EEB06106.2 - 2e-08 34.7 0.0 5.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 SET domain CLAMP PF14769.1 EEB06106.2 - 0.098 12.8 0.5 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 BolA PF01722.13 EEB06107.1 - 6.1e-19 67.7 0.0 8.6e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein DUF3124 PF11322.3 EEB06107.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3124) Ins_P5_2-kin PF06090.7 EEB06108.1 - 1.6e-36 125.9 0.0 9.1e-36 123.4 0.0 2.3 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase BAR PF03114.13 EEB06108.1 - 3.5e-07 29.9 0.7 1.5e-06 27.8 0.6 1.9 2 0 0 2 2 2 1 BAR domain 7TMR-HDED PF07697.6 EEB06108.1 - 0.043 13.5 0.0 1.5 8.5 0.0 2.7 1 1 0 1 1 1 0 7TM-HD extracellular DUF964 PF06133.6 EEB06108.1 - 0.36 10.8 4.6 1 9.4 0.6 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF964) IncA PF04156.9 EEB06108.1 - 1.2 8.6 6.6 0.77 9.3 3.0 1.8 2 0 0 2 2 2 0 IncA protein Ribosomal_L12 PF00542.14 EEB06109.1 - 3.8e-20 71.6 4.7 3.8e-20 71.6 3.3 2.7 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EEB06109.1 - 6.4 7.2 12.3 0.21 12.0 3.0 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein CTK3 PF12243.3 EEB06110.1 - 1e-47 161.2 0.0 1.5e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EEB06110.1 - 1.7e-16 59.9 6.0 1.7e-16 59.9 4.1 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Nro1 PF12753.2 EEB06111.1 - 2e-86 290.4 14.4 1.1e-85 288.0 10.0 1.8 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 CDC73 PF05179.9 EEB06112.1 - 9.7e-85 284.2 0.0 1.2e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Rho_N PF07498.7 EEB06112.1 - 0.1 12.4 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain HA2 PF04408.18 EEB06113.1 - 6.3e-27 93.5 0.1 4.8e-26 90.7 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEB06113.1 - 2.1e-22 79.0 0.0 7.6e-22 77.2 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEB06113.1 - 6.2e-14 51.6 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB06113.1 - 9.9e-07 28.4 0.2 2.7e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB06113.1 - 1e-05 25.7 0.1 2.3e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEB06113.1 - 0.00055 19.8 0.1 0.63 9.8 0.0 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEB06113.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 EEB06113.1 - 0.0021 17.5 0.3 0.0062 16.0 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EEB06113.1 - 0.0057 15.5 0.0 0.039 12.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 EEB06113.1 - 0.0066 15.4 0.5 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EEB06113.1 - 0.0071 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EEB06113.1 - 0.026 13.9 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEB06113.1 - 0.039 13.4 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEB06113.1 - 0.039 14.2 0.0 0.18 12.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EEB06113.1 - 0.041 13.5 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase Miro PF08477.8 EEB06113.1 - 0.08 13.4 0.2 0.39 11.2 0.1 2.4 2 1 0 2 2 1 0 Miro-like protein AAA_23 PF13476.1 EEB06113.1 - 0.087 13.1 0.0 0.087 13.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EEB06113.1 - 0.092 12.6 0.1 0.54 10.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EEB06113.1 - 0.14 11.7 0.9 0.65 9.6 0.7 2.2 1 1 0 1 1 1 0 NACHT domain WD40 PF00400.27 EEB06114.1 - 6.7e-28 95.5 13.9 9.7e-11 41.1 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 EEB06115.1 - 5.5e-47 159.1 0.0 7.2e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EEB06115.1 - 3.6e-15 56.6 0.0 5.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EEB06115.1 - 0.00086 18.8 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEB06115.1 - 0.0026 17.1 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EEB06115.1 - 0.07 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF2416 PF10315.4 EEB06116.1 - 1.1e-28 99.5 1.2 1.1e-28 99.5 0.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2416) DPM2 PF07297.7 EEB06117.1 - 2.4e-24 85.3 4.3 2.6e-24 85.2 3.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EEB06117.1 - 5.8e-06 25.9 1.7 6e-06 25.9 1.2 1.1 1 0 0 1 1 1 1 PIG-P 7TM_GPCR_Str PF10326.4 EEB06117.1 - 0.014 14.5 4.9 0.016 14.3 3.4 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF998 PF06197.8 EEB06117.1 - 0.029 13.6 0.3 0.033 13.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1772 PF08592.6 EEB06117.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2975 PF11188.3 EEB06117.1 - 1.8 8.2 5.2 2.2 8.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Homeobox PF00046.24 EEB06119.1 - 3.1e-13 49.1 7.1 8.9e-13 47.6 4.9 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEB06119.1 - 0.027 14.1 0.2 0.096 12.4 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF3408 PF11888.3 EEB06119.1 - 0.63 9.9 6.6 1.3 8.9 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) tRNA-synt_1g PF09334.6 EEB06121.1 - 4.6e-145 483.1 0.2 5.9e-145 482.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEB06121.1 - 1.6e-08 33.0 1.0 0.00018 19.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.5 EEB06121.1 - 0.00017 21.9 0.8 0.00083 19.7 0.5 2.1 1 1 0 1 1 1 1 MetRS-N binding domain Anticodon_1 PF08264.8 EEB06121.1 - 0.00096 18.9 0.2 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DnaJ PF00226.26 EEB06122.1 - 5.5e-24 83.6 4.4 1.1e-23 82.7 3.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EEB06122.1 - 3.2e-19 69.1 0.5 6.8e-19 68.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) MerR_1 PF13411.1 EEB06122.1 - 0.061 13.0 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein DSPc PF00782.15 EEB06123.1 - 1e-33 115.7 0.1 1.4e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEB06123.1 - 1.7e-05 24.2 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TAP35_44 PF07265.6 EEB06123.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 CDKN3 PF05706.7 EEB06123.1 - 0.045 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Yippee-Mis18 PF03226.9 EEB06123.1 - 0.067 13.2 0.2 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase3 PF13350.1 EEB06123.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Zn_Tnp_IS1595 PF12760.2 EEB06123.1 - 7.6 6.4 9.8 3.2 7.6 3.0 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Pyr_redox_2 PF07992.9 EEB06124.1 - 6e-37 127.4 0.1 9.4e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEB06124.1 - 4.6e-32 110.3 0.0 1.9e-31 108.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEB06124.1 - 5.4e-19 68.3 2.8 6.4e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB06124.1 - 5e-09 36.5 0.0 1.9e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEB06124.1 - 4.7e-07 29.2 0.1 6.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EEB06124.1 - 6.5e-05 22.0 0.0 9.4e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEB06124.1 - 0.00062 18.9 1.5 0.016 14.2 0.6 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EEB06124.1 - 0.00067 18.6 0.9 0.00067 18.6 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EEB06124.1 - 0.0011 18.6 0.3 0.046 13.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEB06124.1 - 0.0012 17.3 2.1 0.011 14.2 0.5 2.8 3 1 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EEB06124.1 - 0.0064 16.4 6.3 0.0064 16.4 4.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEB06124.1 - 0.0069 15.2 4.1 0.011 14.5 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EEB06124.1 - 0.0087 15.6 0.3 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EEB06124.1 - 0.009 14.9 4.8 0.0076 15.1 2.2 1.8 2 1 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EEB06124.1 - 0.0093 15.1 2.6 0.043 12.9 0.1 2.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEB06124.1 - 0.068 12.8 0.6 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EEB06124.1 - 0.21 10.6 1.9 0.65 8.9 0.7 2.1 2 0 0 2 2 2 0 FAD binding domain TatD_DNase PF01026.16 EEB06125.2 - 1e-55 188.7 0.0 1.3e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EEB06125.2 - 0.078 12.5 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase BPL_LplA_LipB PF03099.14 EEB06126.1 - 1.6e-23 83.1 0.3 3.9e-23 81.8 0.2 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family zf-RING_2 PF13639.1 EEB06127.1 - 1.8e-11 43.6 12.0 5.4e-11 42.1 7.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB06127.1 - 3.1e-10 39.9 9.3 7.7e-10 38.6 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB06127.1 - 2e-09 37.1 5.3 8.4e-09 35.1 3.6 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEB06127.1 - 6.1e-09 35.3 8.8 1.6e-08 34.0 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06127.1 - 1.4e-08 34.3 7.5 1.4e-08 34.3 5.2 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEB06127.1 - 1.1e-07 31.3 6.7 2.2e-07 30.4 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB06127.1 - 2.7e-05 23.7 3.1 4.3e-05 23.1 1.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EEB06127.1 - 0.00029 20.8 8.5 0.00029 20.8 5.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EEB06127.1 - 0.0013 18.4 2.8 0.003 17.2 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 EEB06127.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.1 EEB06127.1 - 0.026 14.0 5.8 0.053 13.0 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EEB06127.1 - 0.065 13.0 3.2 0.14 11.9 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 EEB06127.1 - 0.14 12.0 7.9 0.49 10.3 2.9 2.6 1 1 1 2 2 2 0 IBR domain zf-RING_4 PF14570.1 EEB06127.1 - 0.29 10.7 8.1 0.62 9.6 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINT1_TIP1 PF04437.8 EEB06128.1 - 2.5e-65 220.9 10.7 3.7e-65 220.3 7.4 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Adaptin_N PF01602.15 EEB06129.1 - 1.5e-105 353.5 15.4 2.1e-105 353.0 10.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EEB06129.1 - 1.2e-31 108.9 0.0 2.5e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EEB06129.1 - 6.8e-10 39.2 0.1 2.1e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain AP4E_app_platf PF14807.1 EEB06129.1 - 0.0001 22.4 0.0 0.00032 20.8 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 EEB06129.1 - 0.057 13.6 0.0 2.7 8.3 0.0 3.5 3 1 0 3 3 3 0 HEAT repeats DUF4050 PF13259.1 EEB06129.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Anoctamin PF04547.7 EEB06130.2 - 1.2e-97 327.4 11.4 1.4e-97 327.1 7.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_1 PF00076.17 EEB06131.2 - 2.4e-71 235.3 7.4 1e-19 69.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06131.2 - 6.1e-65 215.1 1.9 1.4e-15 57.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06131.2 - 1e-35 121.3 0.2 9.9e-08 31.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEB06131.2 - 1.2e-05 24.9 2.3 13 5.6 0.0 6.2 5 2 1 6 6 6 1 Limkain b1 Nup35_RRM_2 PF14605.1 EEB06131.2 - 0.0026 17.4 0.0 0.6 9.9 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Cellulase PF00150.13 EEB06132.1 - 2.3e-14 53.2 3.6 3.4e-14 52.7 2.5 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PseudoU_synth_2 PF00849.17 EEB06133.1 - 2.6e-31 108.6 0.0 3.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.7 EEB06133.1 - 0.057 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) XPG_I PF00867.13 EEB06134.1 - 3.6e-15 55.7 0.0 1.3e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EEB06134.1 - 5.1e-15 55.5 0.0 1.3e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EEB06134.1 - 0.00013 22.1 0.0 0.00043 20.4 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Caldesmon PF02029.10 EEB06134.1 - 0.093 11.1 2.8 0.12 10.7 1.9 1.1 1 0 0 1 1 1 0 Caldesmon DUF3585 PF12130.3 EEB06134.1 - 5.3 6.9 9.3 3 7.6 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3585) DUF155 PF02582.9 EEB06135.1 - 1e-58 198.0 0.0 1.9e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 WD40 PF00400.27 EEB06136.1 - 2.4e-55 182.5 14.0 5.4e-09 35.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEB06136.1 - 5.2e-07 29.5 0.2 0.056 13.1 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEB06136.1 - 0.00039 18.7 1.3 0.78 7.8 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PAP_assoc PF03828.14 EEB06137.1 - 2.2e-15 56.3 0.1 7.1e-15 54.6 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB06137.1 - 1.1e-12 48.0 0.0 3e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2651 PF10852.3 EEB06137.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) Nuc_sug_transp PF04142.10 EEB06138.2 - 4.7e-11 42.2 2.3 7.9e-11 41.5 1.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EEB06138.2 - 1.3e-07 31.6 13.3 1.5e-06 28.2 4.6 3.0 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEB06138.2 - 4.3e-06 25.8 7.7 5.6e-06 25.4 4.1 1.7 1 1 1 2 2 2 1 UAA transporter family EmrE PF13536.1 EEB06138.2 - 8.3e-06 25.9 6.5 8.3e-06 25.9 4.5 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EEB06138.2 - 8.4e-06 24.8 6.8 1.2e-05 24.3 4.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EEB06138.2 - 0.0014 18.3 0.9 0.0038 17.0 0.6 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 UPF0197 PF05251.7 EEB06138.2 - 1.1 9.6 11.3 2.3 8.6 2.0 3.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) Peptidase_M50B PF13398.1 EEB06138.2 - 1.7 7.9 15.0 12 5.2 10.7 2.1 1 1 1 2 2 2 0 Peptidase M50B-like CHD5 PF04420.9 EEB06139.1 - 9.4e-38 129.4 1.9 1.1e-37 129.2 1.3 1.0 1 0 0 1 1 1 1 CHD5-like protein Peptidase_M41 PF01434.13 EEB06140.1 - 1.5e-71 240.2 0.7 2.3e-71 239.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEB06140.1 - 3.6e-42 143.7 0.1 9e-41 139.1 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EEB06140.1 - 2.8e-12 46.7 0.1 7.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EEB06140.1 - 0.0002 21.0 0.0 0.0016 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEB06140.1 - 0.0009 20.0 0.0 0.0031 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB06140.1 - 0.00098 19.2 0.0 0.14 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EEB06140.1 - 0.0043 15.8 0.0 0.0076 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EEB06140.1 - 0.0049 16.7 0.0 0.041 13.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEB06140.1 - 0.005 16.8 1.2 0.068 13.1 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EEB06140.1 - 0.0053 16.1 0.6 0.031 13.6 0.2 2.3 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EEB06140.1 - 0.0055 16.4 1.8 0.011 15.4 0.3 2.2 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EEB06140.1 - 0.0092 15.0 0.0 0.023 13.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEB06140.1 - 0.029 13.7 0.1 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEB06140.1 - 0.034 13.2 0.2 0.13 11.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Plasmodium_Vir PF05795.6 EEB06140.1 - 0.055 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AAA_14 PF13173.1 EEB06140.1 - 0.092 12.6 0.0 0.34 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEB06140.1 - 0.14 11.3 0.2 0.37 9.9 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4455 PF14643.1 EEB06140.1 - 0.18 10.3 2.2 2.7 6.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Scs3p PF10261.4 EEB06141.1 - 6.6e-52 175.9 26.9 1.4e-49 168.3 18.6 2.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pkinase PF00069.20 EEB06142.2 - 8.2e-60 202.1 0.0 1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06142.2 - 5.2e-37 127.3 0.0 7e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06142.2 - 9.6e-09 34.6 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB06142.2 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB06142.2 - 0.16 10.7 0.1 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 EEB06143.1 - 9.3e-41 139.1 0.0 5.3e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB06143.1 - 2.7e-25 88.0 0.1 6e-25 86.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB06143.1 - 3.3e-06 27.0 0.7 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HCO3_cotransp PF00955.16 EEB06144.1 - 2.9e-60 204.4 12.4 2.3e-37 128.8 2.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family NPR3 PF03666.8 EEB06145.1 - 2.2e-119 398.9 9.5 1.7e-118 396.0 6.6 1.9 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Nic96 PF04097.9 EEB06146.1 - 1e-139 466.4 0.0 1.3e-139 466.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Apc3 PF12895.2 EEB06146.1 - 0.0065 16.5 3.0 1.1 9.4 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Flg_bb_rod PF00460.15 EEB06146.1 - 0.15 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Flagella basal body rod protein HSP70 PF00012.15 EEB06147.1 - 2.4e-273 907.5 4.4 2.7e-273 907.4 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB06147.1 - 7.1e-16 57.7 0.1 1.3e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEB06147.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Macoilin PF09726.4 EEB06147.1 - 0.003 15.9 0.5 0.0047 15.2 0.1 1.4 2 0 0 2 2 2 1 Transmembrane protein Hydantoinase_A PF01968.13 EEB06147.1 - 0.0035 16.4 0.1 0.055 12.5 0.0 2.5 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase HGTP_anticodon PF03129.15 EEB06147.1 - 0.04 13.8 0.3 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 Anticodon binding domain Enhancin PF03272.8 EEB06147.1 - 0.49 8.2 2.0 0.78 7.5 1.4 1.2 1 0 0 1 1 1 0 Viral enhancin protein TarH PF02203.10 EEB06147.1 - 1.1 9.0 4.3 2.2 8.0 3.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Metallophos PF00149.23 EEB06148.1 - 8.2e-44 149.4 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NOSIC PF08060.8 EEB06148.1 - 0.05 13.4 0.2 0.23 11.2 0.0 2.2 3 0 0 3 3 3 0 NOSIC (NUC001) domain LRR_4 PF12799.2 EEB06149.1 - 1.6e-27 94.5 46.0 3.3e-06 26.6 2.0 9.1 5 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB06149.1 - 1.6e-22 79.0 41.7 2e-07 30.6 2.4 7.7 4 2 5 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 EEB06149.1 - 3.8e-09 35.3 48.6 0.026 14.5 1.0 14.1 13 2 2 15 15 15 3 Leucine Rich Repeat LRR_7 PF13504.1 EEB06149.1 - 1.2e-06 27.7 33.6 1 9.8 0.2 12.8 14 0 0 14 14 14 2 Leucine rich repeat LRR_6 PF13516.1 EEB06149.1 - 1.6e-05 24.5 28.4 0.77 10.0 0.0 10.6 9 2 2 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 EEB06149.1 - 0.00041 19.9 11.7 0.038 13.5 0.5 3.3 2 1 1 3 3 3 2 Leucine-rich repeat SUR7 PF06687.7 EEB06150.1 - 8.3e-19 67.9 20.1 1.2e-18 67.5 13.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family ELO PF01151.13 EEB06150.1 - 0.0073 15.6 2.1 0.01 15.1 1.4 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family COX6A PF02046.10 EEB06151.2 - 1.1e-30 105.9 0.1 1.1e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Sas10_Utp3 PF04000.10 EEB06152.1 - 7.1e-18 64.5 1.4 1.1e-17 63.9 1.0 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family FadA PF09403.5 EEB06152.1 - 0.0032 17.4 1.5 0.098 12.6 0.1 2.2 2 0 0 2 2 2 1 Adhesion protein FadA DUF4591 PF15261.1 EEB06152.1 - 0.036 14.3 0.4 0.076 13.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) BLOC1_2 PF10046.4 EEB06152.1 - 0.049 13.7 1.8 0.44 10.7 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Complex1_LYR_2 PF13233.1 EEB06152.1 - 0.089 13.2 0.5 0.16 12.4 0.4 1.5 1 1 0 1 1 1 0 Complex1_LYR-like TP_methylase PF00590.15 EEB06153.2 - 6.8e-50 169.6 0.0 1.4e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EEB06153.2 - 1.3e-06 28.5 0.1 7.6e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEB06153.2 - 0.0017 17.5 0.1 0.0052 16.0 0.0 1.8 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal SET PF00856.23 EEB06154.1 - 1.3e-14 54.8 0.0 2.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 SET domain DASH_Spc19 PF08287.6 EEB06155.1 - 1.7e-26 92.7 11.8 1.5e-25 89.6 8.2 1.9 1 1 0 1 1 1 1 Spc19 AAA_13 PF13166.1 EEB06155.1 - 0.0057 15.1 0.3 0.0061 15.0 0.2 1.0 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.4 EEB06155.1 - 0.01 15.9 2.0 0.58 10.3 0.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 EEB06155.1 - 0.014 15.4 0.4 0.26 11.2 0.0 2.3 1 1 0 2 2 2 0 DASH complex subunit Dad2 HALZ PF02183.13 EEB06155.1 - 0.015 15.0 2.9 2.4 7.9 0.0 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EEB06155.1 - 0.094 12.6 0.5 4.2 7.3 0.0 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EEB06155.1 - 0.11 12.6 4.1 0.37 10.9 0.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.12 EEB06155.1 - 0.11 12.1 4.5 3.4 7.3 0.2 3.2 2 2 1 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.16 EEB06155.1 - 0.4 10.6 3.6 7.8 6.5 0.4 3.1 3 0 0 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EEB06155.1 - 0.45 10.5 2.9 1.6 8.7 1.2 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 EEB06155.1 - 7.2 7.0 10.7 2.2 8.7 0.5 3.3 3 1 1 4 4 4 0 SlyX Ribosomal_L37e PF01907.14 EEB06156.1 - 3.3e-27 94.0 11.6 6.1e-27 93.1 8.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EEB06156.1 - 0.0017 18.1 2.0 0.0026 17.5 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EEB06156.1 - 0.17 11.5 0.5 0.24 11.1 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EEB06156.1 - 0.35 10.1 4.0 3.1 7.1 2.8 2.1 1 1 2 3 3 3 0 zinc-ribbon domain zf-CCHC_5 PF14787.1 EEB06156.1 - 0.5 9.9 4.5 0.97 8.9 3.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C3HC4_2 PF13923.1 EEB06156.1 - 1.7 8.7 5.3 2.7 8.1 3.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kelch_4 PF13418.1 EEB06157.1 - 5.4e-39 131.7 6.0 2.7e-08 33.4 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EEB06157.1 - 1e-38 130.6 14.5 1.6e-07 31.3 0.0 6.7 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EEB06157.1 - 1.4e-34 117.4 3.5 1.7e-05 24.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EEB06157.1 - 2.6e-33 113.3 0.0 7.5e-10 38.1 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EEB06157.1 - 3e-33 112.6 2.9 9.1e-08 31.9 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EEB06157.1 - 2.3e-26 90.5 0.7 1.8e-05 24.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Elongin_A PF06881.6 EEB06157.1 - 3.7 7.9 10.7 0.075 13.4 0.6 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A tRNA-synt_2 PF00152.15 EEB06158.1 - 5.8e-84 281.7 0.1 1e-83 280.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEB06158.1 - 3.8e-05 23.4 0.8 6.8e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEB06158.1 - 0.004 16.3 0.8 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 EEB06158.1 - 3.1 7.5 8.3 0.6 9.9 3.2 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Atrophin-1 PF03154.10 EEB06158.1 - 8.4 4.3 5.7 12 3.8 4.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family FSH1 PF03959.8 EEB06159.1 - 4.5e-62 209.2 0.0 6.1e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DHFR_1 PF00186.14 EEB06159.1 - 1.5e-28 99.3 0.0 2.2e-27 95.6 0.0 2.3 1 1 0 1 1 1 1 Dihydrofolate reductase Abhydrolase_5 PF12695.2 EEB06159.1 - 1.9e-06 27.6 0.0 8.2e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB06159.1 - 0.001 18.9 0.0 0.2 11.5 0.0 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEB06159.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEB06159.1 - 0.062 12.7 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EEB06159.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain AhpC-TSA PF00578.16 EEB06160.1 - 4.5e-39 132.9 0.0 5.8e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEB06160.1 - 9.7e-19 67.3 0.0 1.2e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEB06160.1 - 9e-09 34.8 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Slu7 PF11708.3 EEB06161.1 - 2e-47 161.9 15.7 4e-47 161.0 10.9 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EEB06161.1 - 0.012 15.2 0.6 0.027 14.1 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EEB06161.1 - 0.3 11.0 2.1 0.5 10.3 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_6 PF14259.1 EEB06162.1 - 9.7e-16 57.5 0.6 1.8e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB06162.1 - 5.4e-13 48.3 0.0 5.4e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06162.1 - 0.0042 16.9 0.0 0.0042 16.9 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_27 PF13514.1 EEB06162.1 - 1.2 6.6 11.8 0.039 11.6 2.8 1.9 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 EEB06162.1 - 4.2 7.0 8.8 0.52 9.9 3.0 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_L21e PF01157.13 EEB06163.1 - 4.6e-39 132.2 6.4 7.3e-39 131.5 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e BCNT PF07572.7 EEB06163.1 - 0.13 12.2 0.9 0.22 11.5 0.6 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development SAC3_GANP PF03399.11 EEB06164.1 - 7.3e-23 81.1 1.0 1.1e-22 80.6 0.7 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEB06164.1 - 2.3e-20 72.8 0.2 4e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 NHase_beta PF02211.10 EEB06164.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit KAT11 PF08214.6 EEB06165.1 - 2.6e-59 201.0 0.9 3e-59 200.8 0.6 1.0 1 0 0 1 1 1 1 Histone acetylation protein Toxin_18 PF08087.6 EEB06165.1 - 0.021 14.5 1.2 0.038 13.7 0.9 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily Sarcoglycan_1 PF04790.8 EEB06165.1 - 0.056 12.5 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein BRCT PF00533.21 EEB06166.1 - 1.4e-13 50.7 1.6 2.8e-12 46.5 0.1 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad9_Rad53_bind PF08605.5 EEB06166.1 - 2.7e-06 27.2 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding DUF4537 PF15057.1 EEB06166.1 - 0.028 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Cg6151-P PF10233.4 EEB06167.2 - 1.3e-32 112.0 11.7 1.6e-32 111.8 8.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 EEB06167.2 - 0.006 15.9 4.5 0.006 15.9 3.1 2.0 1 1 1 2 2 2 1 PRA1 family protein Cytochrom_B558a PF05038.8 EEB06167.2 - 0.032 13.8 8.3 0.28 10.7 5.8 2.0 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF4418 PF14387.1 EEB06167.2 - 0.71 9.6 6.5 0.26 11.0 2.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) DUF2754 PF10953.3 EEB06167.2 - 0.99 9.5 3.7 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) YwiC PF14256.1 EEB06167.2 - 5.9 6.9 10.8 10 6.2 6.6 1.8 1 1 1 2 2 2 0 YwiC-like protein Tbf5 PF06331.7 EEB06168.1 - 2.3e-25 88.1 0.1 2.5e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ThiS PF02597.15 EEB06168.1 - 0.089 13.2 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 ThiS family PGM_PMM_I PF02878.11 EEB06170.1 - 5.9e-38 129.4 0.2 8.8e-38 128.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEB06170.1 - 7.4e-20 71.0 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEB06170.1 - 7.1e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEB06170.1 - 5.3e-08 32.7 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DASH_Duo1 PF08651.5 EEB06172.1 - 1.5e-21 75.7 3.0 2.5e-21 75.0 2.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 GAGA_bind PF06217.7 EEB06172.1 - 0.035 14.0 6.3 0.055 13.4 4.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PNMA PF14893.1 EEB06172.1 - 0.045 12.7 6.1 0.065 12.2 4.2 1.3 1 0 0 1 1 1 0 PNMA Asp-B-Hydro_N PF05279.6 EEB06172.1 - 0.18 11.6 7.4 0.26 11.1 5.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1682 PF07946.9 EEB06172.1 - 0.21 10.3 14.7 0.29 9.9 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.1 EEB06172.1 - 6.9 5.5 11.1 9.4 5.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EEB06172.1 - 7.4 5.5 14.2 10 5.0 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RINGv PF12906.2 EEB06173.2 - 0.0001 22.2 2.9 0.00032 20.6 2.0 1.9 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EEB06173.2 - 0.0049 16.6 2.9 0.0049 16.6 2.0 2.3 2 1 0 2 2 2 1 Ring finger domain DUF3726 PF12525.3 EEB06173.2 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) FANCL_C PF11793.3 EEB06173.2 - 0.37 10.7 3.3 1.4 8.9 1.2 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain Cyclin_N PF00134.18 EEB06174.1 - 1.9e-21 75.9 1.0 4e-21 74.9 0.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB06174.1 - 8.1e-06 25.7 0.5 0.019 14.8 0.0 2.8 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EEB06174.1 - 0.00016 21.4 0.1 0.00038 20.2 0.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat MtrB PF05440.7 EEB06174.1 - 0.052 13.5 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Desmo_N PF06771.6 EEB06174.1 - 0.08 12.8 0.2 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus BSD PF03909.12 EEB06174.1 - 0.088 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 BSD domain Isy1 PF06246.7 EEB06175.1 - 4.8e-59 199.8 6.4 7.9e-58 195.8 4.4 1.9 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EEB06175.1 - 0.024 14.4 0.2 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 YolD-like protein MIS13 PF08202.6 EEB06175.1 - 0.037 13.0 0.2 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Tubulin PF00091.20 EEB06176.1 - 7.7e-72 241.6 0.0 1.3e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEB06176.1 - 1.7e-46 157.3 0.2 7.6e-46 155.2 0.0 2.1 3 0 0 3 3 3 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEB06176.1 - 2.4e-06 27.5 0.0 6.3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEB06176.1 - 0.0031 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GSHPx PF00255.14 EEB06177.2 - 8e-45 150.6 0.1 1.1e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EEB06177.2 - 3.5e-05 23.4 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEB06177.2 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin Gemin7 PF11095.3 EEB06178.1 - 7.8e-13 47.9 0.0 9.4e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) WD40 PF00400.27 EEB06179.1 - 1e-30 104.4 15.1 1.5e-07 31.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EEB06179.1 - 7e-08 32.4 0.0 0.00035 20.3 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EEB06179.1 - 0.00054 19.1 0.2 0.63 9.0 0.0 3.1 1 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EEB06179.1 - 0.001 17.9 0.3 0.23 10.1 0.0 2.9 2 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EEB06179.1 - 0.0012 17.1 1.4 0.43 8.6 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EEB06179.1 - 0.0026 16.7 0.3 0.9 8.3 0.0 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EEB06179.1 - 0.08 11.2 0.2 1 7.5 0.0 2.4 2 1 1 3 3 3 0 Cytochrome D1 heme domain Exo_endo_phos PF03372.18 EEB06180.1 - 3.7e-19 69.6 1.7 4.9e-19 69.2 1.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3099 PF11298.3 EEB06180.1 - 2.3 8.0 5.8 4.1 7.2 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Memo PF01875.12 EEB06181.1 - 2.2e-82 276.0 0.0 2.5e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein UvrD_C PF13361.1 EEB06182.2 - 7.4e-76 255.8 0.4 1.8e-75 254.5 0.3 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EEB06182.2 - 7.5e-62 209.4 0.0 1.8e-61 208.1 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EEB06182.2 - 1.1e-12 47.4 0.0 5.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EEB06182.2 - 9.3e-12 45.0 0.0 3.5e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EEB06182.2 - 4.8e-06 26.2 0.2 0.004 16.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EEB06182.2 - 4.8e-05 23.0 0.0 0.00093 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEB06182.2 - 0.00082 18.8 0.1 0.14 11.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain DGF-1_C PF11040.3 EEB06182.2 - 0.19 11.6 1.6 0.69 9.8 0.8 2.1 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RRM_1 PF00076.17 EEB06183.1 - 2e-86 283.6 3.5 5.9e-22 77.0 0.3 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06183.1 - 4.5e-55 183.5 0.6 1.7e-16 59.9 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06183.1 - 2.5e-42 142.4 0.3 1.4e-09 37.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEB06183.1 - 2.2e-25 88.0 0.8 8.9e-25 86.1 0.2 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EEB06183.1 - 0.00035 20.2 0.1 2.2 8.1 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EEB06183.1 - 0.0021 18.2 0.0 4 7.7 0.0 3.6 3 0 0 3 3 3 1 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EEB06183.1 - 0.0049 16.5 1.9 0.4 10.4 0.1 3.6 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.6 EEB06183.1 - 0.094 12.2 2.0 29 4.2 0.1 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain MMgT PF10270.4 EEB06184.1 - 3.9e-15 56.1 0.0 5.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Myc-LZ PF02344.10 EEB06184.1 - 0.084 12.5 0.3 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain DASH_Dam1 PF08653.5 EEB06185.1 - 1.1e-18 66.7 1.8 1.7e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 DASH complex subunit Dam1 Spectrin PF00435.16 EEB06185.1 - 0.0013 18.9 0.9 0.0083 16.3 0.0 2.0 2 0 0 2 2 2 1 Spectrin repeat AKNA PF12443.3 EEB06185.1 - 0.0029 17.6 2.5 0.0087 16.0 0.2 2.0 2 0 0 2 2 2 1 AT-hook-containing transcription factor NIT PF08376.5 EEB06185.1 - 0.0079 15.7 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing DUF904 PF06005.7 EEB06185.1 - 0.0091 16.2 2.6 0.093 13.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF904) FTA4 PF13093.1 EEB06185.1 - 0.017 14.5 1.5 0.025 14.0 1.0 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2802 PF10975.3 EEB06185.1 - 0.19 11.5 2.0 0.29 10.9 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) Rootletin PF15035.1 EEB06185.1 - 0.26 11.2 3.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CRAL_TRIO PF00650.15 EEB06186.1 - 1.3e-35 122.2 0.1 2e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEB06186.1 - 1.5e-08 34.6 0.1 2.7e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EutQ PF06249.7 EEB06186.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ CRAL_TRIO_N PF03765.10 EEB06186.1 - 0.033 14.3 0.1 0.12 12.4 0.1 2.0 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain ubiquitin PF00240.18 EEB06187.1 - 2.6e-34 116.4 0.9 2.6e-34 116.4 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EEB06187.1 - 8.7e-25 86.2 2.1 1.6e-24 85.4 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EEB06187.1 - 4.8e-20 71.0 0.7 9.8e-20 70.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB06187.1 - 3.4e-06 27.2 0.5 3.8e-05 23.8 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB06187.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB06187.1 - 0.00047 20.0 0.6 0.001 18.9 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-ribbon_3 PF13248.1 EEB06187.1 - 0.0012 18.0 0.6 0.0023 17.0 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF2407 PF10302.4 EEB06187.1 - 0.0041 17.2 0.4 0.0055 16.8 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DZR PF12773.2 EEB06187.1 - 0.0082 15.9 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon Plexin_cytopl PF08337.7 EEB06187.1 - 0.033 12.5 3.5 0.4 8.9 0.2 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EEB06187.1 - 0.055 13.5 0.3 0.12 12.4 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) zinc_ribbon_2 PF13240.1 EEB06187.1 - 0.059 12.8 2.4 0.28 10.7 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF2318 PF10080.4 EEB06187.1 - 0.065 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Nudix_N_2 PF14803.1 EEB06187.1 - 0.093 12.4 2.1 0.33 10.6 1.2 2.1 1 1 1 2 2 2 0 Nudix N-terminal UPF0547 PF10571.4 EEB06187.1 - 0.11 12.2 0.7 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 EEB06187.1 - 0.12 12.0 1.2 0.26 10.9 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EEB06187.1 - 0.14 11.9 1.3 0.24 11.2 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RF-1 PF00472.15 EEB06188.1 - 4.7e-13 48.9 0.3 6.9e-13 48.4 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EEB06188.1 - 0.027 14.5 0.2 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein BTG PF07742.7 EEB06188.1 - 0.042 13.3 0.1 0.13 11.8 0.1 1.7 1 1 1 2 2 2 0 BTG family YqbF PF14553.1 EEB06188.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Frag1 PF10277.4 EEB06189.1 - 1.1e-38 132.8 10.0 1.1e-38 132.8 6.9 3.8 3 2 0 3 3 3 2 Frag1/DRAM/Sfk1 family Mis14 PF08641.7 EEB06190.2 - 3e-18 66.2 0.5 5.1e-18 65.4 0.1 1.5 1 1 0 1 1 1 1 Kinetochore protein Mis14 like Spc7 PF08317.6 EEB06190.2 - 0.0013 17.4 0.8 0.002 16.8 0.5 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1162 PF06650.7 EEB06191.1 - 2.5e-59 200.7 0.1 1.3e-55 188.5 0.0 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EEB06191.1 - 9.6e-38 128.3 4.2 2e-37 127.3 0.6 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEB06191.1 - 0.0054 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Sds3 PF08598.6 EEB06192.1 - 9.1e-13 48.1 6.6 9.1e-13 48.1 4.6 3.5 2 2 1 3 3 3 2 Sds3-like Neur_chan_memb PF02932.11 EEB06192.1 - 3.7 7.3 10.1 20 4.9 7.0 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HIT PF01230.18 EEB06193.1 - 3.5e-24 85.1 0.0 4.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEB06193.1 - 3.9e-13 49.6 0.0 5.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEB06193.1 - 0.00062 19.4 0.0 0.00085 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 G-patch PF01585.18 EEB06194.1 - 4.3e-14 52.0 2.2 9.7e-14 50.8 1.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEB06194.1 - 0.0091 15.8 0.2 0.0091 15.8 0.2 2.9 3 1 0 3 3 3 1 DExH-box splicing factor binding site Mucin PF01456.12 EEB06194.1 - 0.015 15.0 1.0 0.015 15.0 0.7 3.1 3 1 0 3 3 3 0 Mucin-like glycoprotein CDP-OH_P_transf PF01066.16 EEB06195.2 - 1.9e-12 47.3 4.1 1.9e-12 47.3 2.9 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EEB06196.1 - 2.3e-43 147.3 0.1 2.3e-43 147.3 0.1 1.9 1 1 2 3 3 3 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EEB06197.1 - 2.6e-47 160.5 0.1 4.6e-47 159.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEB06197.1 - 8.1e-21 73.7 0.1 2e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EEB06197.1 - 3.5e-17 61.9 0.0 3.7e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 EEB06197.1 - 1.6e-12 47.0 0.0 3.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Vac14_Fig4_bd PF11916.3 EEB06198.1 - 1.7e-56 190.2 6.7 6.4e-48 162.2 3.4 2.6 1 1 1 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EEB06198.1 - 6.2e-41 138.7 1.6 4e-37 126.5 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EEB06198.1 - 2.8e-11 42.4 0.7 0.0068 16.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EEB06198.1 - 3.5e-09 36.8 0.0 0.22 11.8 0.0 4.7 3 2 1 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EEB06198.1 - 2.3e-07 31.0 0.6 0.49 10.9 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat DUF2454 PF10521.4 EEB06198.1 - 0.00078 18.5 4.5 2.9 6.8 0.3 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF2454) Cnd1 PF12717.2 EEB06198.1 - 0.0033 17.3 5.5 0.94 9.2 0.0 3.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AMMECR1 PF01871.12 EEB06199.1 - 3.8e-43 146.5 0.0 4.6e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 PP-binding PF00550.20 EEB06200.1 - 3.8e-12 46.2 0.1 4.4e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EEB06200.1 - 4.9e-05 23.2 0.3 7.2e-05 22.7 0.2 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EEB06200.1 - 0.0074 16.3 0.1 0.0094 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Rhodanese PF00581.15 EEB06201.2 - 2.5e-18 66.4 0.0 3.1e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ArsA_ATPase PF02374.10 EEB06202.1 - 1.2e-113 379.1 0.2 1.4e-113 378.9 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EEB06202.1 - 7.5e-17 61.3 0.0 1e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEB06202.1 - 1.8e-08 34.4 0.0 6.7e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EEB06202.1 - 1.6e-06 27.7 0.2 0.00051 19.5 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EEB06202.1 - 4e-06 26.2 0.2 8.8e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EEB06202.1 - 0.0004 19.8 0.1 0.0061 15.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEB06202.1 - 0.014 14.3 0.2 0.025 13.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EEB06202.1 - 0.026 13.7 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein YhjQ PF06564.7 EEB06202.1 - 0.031 13.6 0.0 0.077 12.3 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein MipZ PF09140.6 EEB06202.1 - 0.036 13.1 0.5 0.12 11.3 0.1 1.9 1 1 1 2 2 2 0 ATPase MipZ Zeta_toxin PF06414.7 EEB06202.1 - 0.038 13.0 0.0 0.088 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.6 EEB06202.1 - 0.089 11.8 1.0 6 5.8 0.0 2.4 3 0 0 3 3 3 0 VirC1 protein IstB_IS21 PF01695.12 EEB06202.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Gp37_Gp68 PF07505.6 EEB06202.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 PhoD PF09423.5 EEB06203.2 - 2.8e-23 82.2 0.1 1.2e-10 40.5 0.4 2.2 1 1 1 2 2 2 2 PhoD-like phosphatase Snf7 PF03357.16 EEB06204.1 - 1.3e-47 161.3 17.9 2e-47 160.7 12.4 1.3 1 0 0 1 1 1 1 Snf7 Hydant_A_N PF05378.8 EEB06204.1 - 0.017 14.6 1.5 0.025 14.1 0.4 1.6 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region Fork_head PF00250.13 EEB06205.2 - 1.2e-30 105.3 0.6 2.4e-30 104.4 0.1 1.8 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 EEB06205.2 - 9.4e-15 54.4 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain cNMP_binding PF00027.24 EEB06206.1 - 1e-41 140.5 0.4 2.7e-20 71.9 0.1 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EEB06206.1 - 7.5e-06 25.2 1.0 2.1e-05 23.8 0.7 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SWIRM PF04433.12 EEB06206.1 - 0.022 14.8 1.7 4.6 7.4 0.0 3.2 2 1 1 3 3 3 0 SWIRM domain DicB PF05358.6 EEB06206.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 DicB protein Pro_isomerase PF00160.16 EEB06207.1 - 4.7e-47 160.0 0.3 5.6e-47 159.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3484 PF11983.3 EEB06208.2 - 1.7 9.5 19.5 8.7 7.2 7.7 4.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) Tyr_Deacylase PF02580.11 EEB06209.2 - 6.9e-53 178.5 1.1 7.7e-53 178.3 0.7 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Fzo_mitofusin PF04799.8 EEB06209.2 - 0.011 15.1 0.2 0.014 14.7 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region PPR_2 PF13041.1 EEB06210.1 - 2.9e-09 36.7 2.8 0.083 12.8 0.0 5.6 6 0 0 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EEB06210.1 - 4.7e-09 35.8 0.5 0.44 10.9 0.0 6.9 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.15 EEB06210.1 - 2.8e-08 33.2 0.5 6.6 6.9 0.0 6.0 5 0 0 5 5 5 4 PPR repeat rRNA_processing PF08524.6 EEB06211.1 - 3.5e-19 69.0 38.9 6e-19 68.2 26.9 1.3 1 1 0 1 1 1 1 rRNA processing DUF1990 PF09348.5 EEB06211.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Mnd1 PF03962.10 EEB06211.1 - 0.68 9.5 17.8 0.87 9.2 12.3 1.3 1 0 0 1 1 1 0 Mnd1 family TAF4 PF05236.9 EEB06211.1 - 1.1 8.4 18.2 1.5 8.0 12.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ArfGap PF01412.13 EEB06211.1 - 2.9 7.6 7.3 4.8 7.0 5.1 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Autophagy_act_C PF03987.10 EEB06212.1 - 7.3e-10 38.8 0.5 1.4e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Mago-bind PF09282.5 EEB06213.1 - 1.6e-13 49.9 0.5 3.9e-13 48.6 0.4 1.7 1 0 0 1 1 1 1 Mago binding YABBY PF04690.8 EEB06213.1 - 0.44 10.7 2.5 0.9 9.7 1.0 1.8 1 1 1 2 2 2 0 YABBY protein zf-UBR PF02207.15 EEB06214.1 - 1.8e-17 62.7 12.0 1.8e-17 62.7 8.3 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EEB06214.1 - 0.00012 21.7 0.1 0.00037 20.1 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS LRR_8 PF13855.1 EEB06215.1 - 7.1e-52 173.0 45.1 6.4e-09 35.4 0.3 9.5 6 2 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 EEB06215.1 - 1.1e-39 133.4 72.6 2.4e-07 30.2 0.7 13.1 6 4 8 15 15 15 14 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.15 EEB06215.1 - 1.8e-38 131.7 0.0 3.1e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PP2C PF00481.16 EEB06215.1 - 1e-27 97.1 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EEB06215.1 - 1.3e-24 82.4 63.2 0.2 11.8 0.1 19.7 19 3 2 21 21 21 8 Leucine Rich Repeat RA PF00788.18 EEB06215.1 - 8e-08 32.6 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EEB06215.1 - 6.8e-07 28.4 60.8 1.1 9.7 0.0 16.9 16 2 1 17 17 17 3 Leucine rich repeat LRR_6 PF13516.1 EEB06215.1 - 1.1e-06 28.0 54.5 0.74 10.0 0.3 15.2 16 1 0 16 16 16 5 Leucine Rich repeat LRR_9 PF14580.1 EEB06215.1 - 0.011 15.3 12.4 0.43 10.1 0.7 4.8 4 1 1 5 5 5 0 Leucine-rich repeat DUF2406 PF10295.4 EEB06216.1 - 4.1e-18 65.6 1.3 1.1e-17 64.2 0.1 2.2 2 2 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF2638 PF10937.3 EEB06216.1 - 0.079 13.9 0.8 0.11 13.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) RCR PF12273.3 EEB06217.1 - 4.5e-12 46.6 0.6 7.3e-12 45.9 0.4 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EEB06217.1 - 0.0024 18.0 0.1 0.0029 17.7 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EEB06217.1 - 0.014 15.5 4.3 0.02 15.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF307 PF03733.8 EEB06217.1 - 0.035 14.5 0.6 0.05 14.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF307) FixP_N PF14715.1 EEB06217.1 - 0.22 10.9 1.1 0.44 9.9 0.8 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ProRS-C_1 PF09180.6 EEB06218.1 - 2.2e-22 78.7 0.7 5.5e-22 77.4 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EEB06218.1 - 3.3e-21 75.6 0.0 9.2e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEB06218.1 - 3.5e-18 65.3 0.0 8.4e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EEB06218.1 - 1.3e-15 57.3 0.6 2.3e-15 56.4 0.4 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA_int_endo PF01974.12 EEB06219.1 - 9.6e-15 54.1 0.0 2.4e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF922 PF06037.6 EEB06219.1 - 0.044 13.1 0.5 0.065 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) LCM PF04072.9 EEB06220.2 - 2.6e-25 89.0 0.1 5.9e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EEB06220.2 - 3.3e-11 42.7 0.2 2.9e-07 30.1 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EEB06220.2 - 1.7e-05 24.8 9.8 0.057 13.5 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EEB06220.2 - 0.00015 21.5 3.6 7.4 6.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EEB06220.2 - 0.0048 17.0 3.7 0.75 10.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif UvdE PF03851.9 EEB06221.2 - 1e-106 356.0 0.0 1.2e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE KilA-N PF04383.8 EEB06222.1 - 0.023 14.3 0.0 3.6 7.2 0.0 2.4 1 1 1 2 2 2 0 KilA-N domain Serglycin PF04360.7 EEB06222.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Serglycin CDC45 PF02724.9 EEB06222.1 - 0.59 8.0 9.7 0.8 7.6 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_15 PF01793.11 EEB06223.1 - 3.5e-136 453.4 12.1 4.4e-136 453.1 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF866 PF05907.8 EEB06224.1 - 4.6e-49 165.9 0.1 5.1e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Herpes_UL55 PF04537.7 EEB06224.1 - 0.0016 17.8 0.1 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL55 protein Basic PF01586.11 EEB06224.1 - 0.0085 16.7 0.2 0.016 15.9 0.1 1.5 1 0 0 1 1 1 1 Myogenic Basic domain DUF3716 PF12511.3 EEB06224.1 - 0.013 15.1 1.8 0.013 15.1 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) DZR PF12773.2 EEB06224.1 - 0.13 12.1 0.4 0.13 12.1 0.3 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-DNA_Pol PF08996.5 EEB06224.1 - 0.97 8.7 4.0 1.5 8.1 1.2 2.0 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger Lar_restr_allev PF14354.1 EEB06224.1 - 1.1 9.6 5.2 2 8.7 0.3 2.7 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-DNL PF05180.7 EEB06224.1 - 9.6 6.0 7.8 31 4.3 0.1 2.7 2 1 0 2 2 2 0 DNL zinc finger ORC6 PF05460.8 EEB06225.1 - 1.9e-18 66.7 3.5 5.1e-16 58.7 0.7 2.1 1 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Actin PF00022.14 EEB06226.1 - 4.4e-83 278.8 0.0 9.5e-83 277.7 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEB06226.1 - 0.0017 17.0 0.0 0.52 8.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsJ PF01728.14 EEB06227.1 - 1.9e-64 216.9 0.0 2.3e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PTPA PF03095.10 EEB06228.1 - 2e-110 368.6 0.0 2.3e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein BPL_LplA_LipB PF03099.14 EEB06229.2 - 4.5e-19 68.6 0.1 8.8e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BUD22 PF09073.5 EEB06230.1 - 1e-58 199.4 35.9 1e-58 199.4 24.9 2.5 1 1 0 1 1 1 1 BUD22 WEMBL PF05701.6 EEB06231.1 - 0.1 11.0 20.9 0.1 11.0 10.6 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light EHN PF06441.7 EEB06231.1 - 0.19 11.6 6.6 1.3 9.0 0.6 2.7 2 1 0 2 2 2 0 Epoxide hydrolase N terminus TPR_MLP1_2 PF07926.7 EEB06231.1 - 0.23 11.2 27.9 1.8 8.2 9.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EEB06231.1 - 2.8 8.2 12.7 2.1 8.6 1.5 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Adeno_PIX PF03955.9 EEB06231.1 - 7.6 7.1 6.9 21 5.6 1.9 2.6 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Tweety PF04906.8 EEB06231.1 - 7.9 4.7 14.0 1.5 7.1 4.8 2.2 1 1 0 2 2 2 0 Tweety DUF883 PF05957.8 EEB06231.1 - 8.4 6.8 7.9 1.9 8.9 0.4 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.6 EEB06231.1 - 9 6.2 7.4 29 4.6 0.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG13 PF10033.4 EEB06232.1 - 1.5e-54 184.8 0.0 2.4e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 CBF PF03914.12 EEB06233.1 - 1.5e-42 144.8 0.0 1.5e-42 144.8 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Anp1 PF03452.9 EEB06234.1 - 2.2e-102 341.8 0.0 2.7e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EEB06234.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF658 PF04936.7 EEB06234.1 - 0.15 11.8 1.0 0.27 11.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Septin PF00735.13 EEB06235.1 - 1.8e-104 348.7 0.2 1.8e-104 348.7 0.2 1.7 2 0 0 2 2 2 1 Septin AAA_10 PF12846.2 EEB06235.1 - 0.00019 20.9 0.0 0.0099 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EEB06235.1 - 0.00023 21.0 0.0 0.00063 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB06235.1 - 0.00049 20.4 0.3 0.0098 16.1 0.0 2.8 2 1 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 EEB06235.1 - 0.002 17.6 0.0 0.042 13.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EEB06235.1 - 0.0057 16.6 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EEB06235.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_32 PF13654.1 EEB06235.1 - 0.0094 14.6 6.9 0.8 8.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EEB06235.1 - 0.014 14.3 0.1 0.18 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EEB06235.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEB06235.1 - 0.024 14.9 2.4 9.5 6.5 1.5 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEB06235.1 - 0.037 14.1 0.2 0.13 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEB06235.1 - 0.076 12.9 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Exonuc_VII_L PF02601.10 EEB06235.1 - 0.6 9.2 7.4 1.3 8.0 5.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.12 EEB06235.1 - 0.92 9.2 4.5 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 CENP-L PF13092.1 EEB06236.1 - 6.4e-33 113.8 0.7 1e-32 113.1 0.5 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 GYF PF02213.11 EEB06237.1 - 4.8e-19 67.6 0.3 9.3e-19 66.7 0.2 1.5 1 0 0 1 1 1 1 GYF domain zf-C2H2_jaz PF12171.3 EEB06238.1 - 2.9e-08 33.6 6.2 5.3e-08 32.7 4.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEB06238.1 - 0.026 14.6 4.7 0.041 13.9 3.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) JAB PF01398.16 EEB06239.2 - 1.3e-17 63.5 0.0 2.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEB06239.2 - 4.1e-09 35.9 0.6 5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EEB06239.2 - 6.7e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain SRP14 PF02290.10 EEB06240.1 - 3.9e-08 33.0 0.0 3.9e-08 33.0 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle 14kD protein CMV_1a PF12467.3 EEB06240.1 - 0.35 11.2 3.1 0.58 10.5 0.5 1.9 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Peptidase_C54 PF03416.14 EEB06241.1 - 7.7e-65 218.7 0.5 4.6e-64 216.2 0.3 1.9 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EEB06241.1 - 0.023 13.8 0.2 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C78 zf-C2H2_2 PF12756.2 EEB06242.1 - 1.2e-22 79.9 13.5 7.7e-21 74.0 1.8 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEB06242.1 - 0.95 9.6 9.2 0.3 11.2 3.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB06242.1 - 0.95 9.7 6.5 3.5 7.9 4.5 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Rhomboid PF01694.17 EEB06243.1 - 5.5e-07 29.7 11.8 5.5e-07 29.7 8.2 1.9 1 1 1 2 2 2 1 Rhomboid family DUF4580 PF15162.1 EEB06243.1 - 0.024 13.9 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) DUF2422 PF10337.4 EEB06243.1 - 0.14 10.9 3.7 0.24 10.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Keratin_assoc PF09775.4 EEB06243.1 - 2.7 7.5 10.9 0.095 12.2 3.2 1.8 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 NIF PF03031.13 EEB06244.2 - 8.9e-26 90.4 0.1 1.7e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEB06244.2 - 2.3e-08 33.7 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl PF00364.17 EEB06244.2 - 0.0038 16.8 0.0 0.91 9.2 0.0 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EEB06244.2 - 0.013 15.0 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like VAD1-2 PF15310.1 EEB06244.2 - 0.015 14.9 1.8 0.054 13.1 0.2 2.1 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling BRCT PF00533.21 EEB06244.2 - 0.065 13.4 0.1 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S30 PF04758.9 EEB06245.1 - 1.8e-28 98.0 4.1 2e-28 97.9 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Glucan_synthase PF02364.10 EEB06246.2 - 0 1297.6 0.0 0 1297.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEB06246.2 - 9.9e-36 122.2 0.7 2.1e-35 121.1 0.5 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EEB06247.1 - 1.5e-132 441.3 6.0 2.2e-132 440.8 4.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEB06247.1 - 3.4e-19 69.0 4.6 1e-18 67.6 3.2 1.9 1 0 0 1 1 1 1 X8 domain TPR_11 PF13414.1 EEB06248.1 - 2.2e-14 52.8 1.1 4.7e-07 29.3 0.0 5.3 3 1 3 6 6 6 4 TPR repeat TPR_2 PF07719.12 EEB06248.1 - 3.4e-11 42.1 0.2 0.0026 17.5 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06248.1 - 4.3e-11 42.4 0.0 0.016 15.7 0.0 6.3 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEB06248.1 - 1.3e-09 37.4 0.2 0.0054 16.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEB06248.1 - 6.3e-06 25.5 0.7 0.36 10.5 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06248.1 - 1.3e-05 24.6 0.0 2.2 8.2 0.0 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06248.1 - 8.7e-05 23.0 0.0 0.048 14.3 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEB06248.1 - 0.0001 22.0 0.3 0.012 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06248.1 - 0.00021 21.5 0.0 0.49 10.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEB06248.1 - 0.00065 18.8 0.2 0.3 10.1 0.0 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 EEB06248.1 - 0.001 18.4 1.1 0.76 9.1 0.0 2.9 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_7 PF13176.1 EEB06248.1 - 0.017 14.8 0.0 14 5.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EEB06248.1 - 0.022 14.8 0.1 0.21 11.7 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB06248.1 - 0.057 13.5 0.2 1.3 9.2 0.0 3.2 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB06248.1 - 0.11 12.5 6.9 8.3 6.4 0.0 5.6 6 2 2 8 8 8 0 Tetratricopeptide repeat Glutaredoxin PF00462.19 EEB06249.1 - 1.1e-19 70.1 0.0 1.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EEB06249.1 - 0.0012 18.5 0.1 0.0022 17.7 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EEB06249.1 - 0.0014 18.8 0.5 0.0055 16.8 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EEB06249.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 EEB06249.1 - 0.038 14.2 0.1 0.046 13.9 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.1 EEB06249.1 - 0.052 13.5 0.0 0.088 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Zn_ribbon_2 PF12674.2 EEB06249.1 - 0.058 13.7 0.1 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain DSBA PF01323.15 EEB06249.1 - 0.096 12.2 0.1 0.97 8.9 0.0 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain zf-HIT PF04438.11 EEB06250.2 - 2.2e-08 33.5 14.3 3.2e-08 33.0 9.9 1.3 1 0 0 1 1 1 1 HIT zinc finger RapA_C PF12137.3 EEB06250.2 - 0.04 12.7 0.1 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Opy2 PF09463.5 EEB06250.2 - 0.096 12.7 8.3 0.19 11.8 5.7 1.6 1 1 0 1 1 1 0 Opy2 protein BSD PF03909.12 EEB06250.2 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 BSD domain zf-MYND PF01753.13 EEB06250.2 - 0.88 9.5 14.4 2 8.3 10.0 1.6 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 EEB06251.1 - 1.5e-05 24.6 3.9 0.0024 17.7 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat CactinC_cactus PF09732.4 EEB06252.2 - 1.8e-50 169.7 2.7 3e-50 169.0 1.9 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EEB06252.2 - 5.4e-35 120.3 2.0 5.4e-35 120.3 1.4 2.0 2 0 0 2 2 2 1 Conserved mid region of cactin Ribosomal_S19e PF01090.14 EEB06253.1 - 3.3e-60 201.5 0.1 3.7e-60 201.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Kinesin PF00225.18 EEB06254.1 - 2.4e-118 394.7 0.0 3.5e-118 394.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Bac_DnaA PF00308.13 EEB06254.1 - 0.16 11.5 2.1 6.6 6.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein PMT_C PF11647.3 EEB06254.1 - 0.19 11.3 1.3 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Filament PF00038.16 EEB06254.1 - 0.79 9.1 7.1 9.3 5.6 4.9 2.3 1 1 0 1 1 1 0 Intermediate filament protein CorA PF01544.13 EEB06254.1 - 3.2 6.7 7.7 16 4.4 0.6 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IMPDH PF00478.20 EEB06255.1 - 2.5e-135 450.9 1.5 2.9e-135 450.7 1.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EEB06255.1 - 1.1e-18 66.7 0.0 1.8e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EEB06255.1 - 1.7e-09 37.0 0.4 6.9e-09 35.0 0.6 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EEB06255.1 - 7e-09 35.2 4.1 2e-06 27.1 2.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EEB06255.1 - 0.0007 18.9 2.6 0.0067 15.7 1.8 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EEB06255.1 - 0.0027 16.8 3.8 0.016 14.2 0.5 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 EEB06255.1 - 0.042 12.9 0.4 0.1 11.7 0.3 1.7 1 1 0 1 1 1 0 KDPG and KHG aldolase adh_short PF00106.20 EEB06255.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glu_synthase PF01645.12 EEB06255.1 - 0.14 11.0 6.6 0.13 11.1 3.1 1.8 1 1 1 2 2 2 0 Conserved region in glutamate synthase zf-DHHC PF01529.15 EEB06256.1 - 1.4e-31 109.2 18.1 1.4e-31 109.2 12.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PTPLA PF04387.9 EEB06257.1 - 3.1e-50 169.7 10.8 3.1e-50 169.7 7.5 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA LSM PF01423.17 EEB06258.2 - 4.7e-15 54.9 0.1 5.9e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2392 PF10288.4 EEB06259.1 - 2.2e-20 72.9 0.0 5.1e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EEB06259.1 - 1.6e-05 24.5 0.0 0.0062 16.0 0.0 2.3 1 1 0 1 1 1 1 PP-loop family L51_S25_CI-B8 PF05047.11 EEB06260.2 - 7.4e-07 28.8 0.1 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ESR1_C PF12743.2 EEB06260.2 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal DUF2404 PF10296.4 EEB06261.1 - 0.0044 17.1 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DGF-1_4 PF11024.3 EEB06261.1 - 0.18 12.1 1.4 0.53 10.7 1.0 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 UPF0300 PF08594.5 EEB06262.1 - 5.1e-05 22.2 0.3 8e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) DUF2014 PF09427.5 EEB06263.2 - 2.1e-50 171.3 0.1 3.3e-50 170.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EEB06263.2 - 1e-18 66.7 0.3 2.2e-18 65.7 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_4 PF07721.9 EEB06263.2 - 0.02 15.2 0.4 0.02 15.2 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1465 PF07323.7 EEB06263.2 - 0.052 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) PRP38 PF03371.10 EEB06264.1 - 2.9e-61 206.0 0.1 3.5e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 PRP38 family CRAL_TRIO_N PF03765.10 EEB06264.1 - 0.29 11.2 2.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Nucleoplasmin PF03066.10 EEB06264.1 - 1.3 8.5 6.8 1.9 7.9 4.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin VPS9 PF02204.13 EEB06265.1 - 4.1e-09 36.4 0.0 9.3e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EEB06265.1 - 6.5e-07 29.5 0.2 0.00026 21.2 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEB06265.1 - 4.9e-06 26.5 1.4 0.00023 21.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEB06265.1 - 2.1e-05 24.8 2.9 0.088 13.3 0.3 4.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB06265.1 - 0.0018 18.3 3.0 0.99 9.8 0.1 5.8 6 0 0 6 6 6 1 Ankyrin repeat PX PF00787.19 EEB06265.1 - 0.026 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 PX domain Ank PF00023.25 EEB06265.1 - 0.64 9.9 3.9 39 4.3 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat F_bP_aldolase PF01116.15 EEB06266.1 - 2.2e-94 315.7 0.0 2.5e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pkinase PF00069.20 EEB06267.1 - 1.8e-59 201.0 0.0 2.5e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06267.1 - 1.8e-26 92.8 0.0 3.8e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06267.1 - 1.7e-07 30.5 0.0 1.3e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EEB06267.1 - 2.8e-05 23.1 0.1 5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEB06267.1 - 0.00019 20.5 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB06267.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEB06267.1 - 0.11 11.8 0.1 0.23 10.7 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EEB06267.1 - 0.12 11.9 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UCH PF00443.24 EEB06268.2 - 6.8e-34 117.2 0.8 8.6e-34 116.8 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RIX1 PF08167.7 EEB06268.2 - 0.037 13.6 0.6 0.35 10.5 0.2 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF4574 PF15141.1 EEB06268.2 - 0.15 11.7 0.1 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) DNA_RNApol_7kD PF03604.8 EEB06269.1 - 1.7e-16 59.3 4.4 2.1e-16 59.0 3.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.13 EEB06269.1 - 0.00043 19.8 0.8 0.57 9.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 EEB06269.1 - 0.0073 16.2 0.9 0.012 15.5 0.6 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.2 EEB06269.1 - 0.0082 15.9 1.1 0.013 15.3 0.8 1.4 1 1 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EEB06269.1 - 0.011 15.3 1.3 0.015 14.9 0.9 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 EEB06269.1 - 0.012 15.0 0.1 0.025 14.0 0.1 1.5 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 EEB06269.1 - 0.012 15.2 0.4 0.015 15.0 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF35_N PF12172.3 EEB06269.1 - 0.012 15.4 0.5 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NinF PF05810.7 EEB06269.1 - 0.013 15.2 0.9 0.018 14.8 0.6 1.2 1 0 0 1 1 1 0 NinF protein zf-C3HC PF07967.8 EEB06269.1 - 0.025 14.3 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like DUF2318 PF10080.4 EEB06269.1 - 0.042 13.6 0.2 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) UPF0547 PF10571.4 EEB06269.1 - 0.051 13.2 1.1 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS1595 PF12760.2 EEB06269.1 - 0.066 13.0 3.2 0.39 10.5 0.3 1.9 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.1 EEB06269.1 - 0.091 12.4 1.1 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal RIG-I_C-RD PF11648.3 EEB06269.1 - 0.18 11.6 0.4 0.18 11.6 0.3 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I Cas_CXXC_CXXC PF09706.5 EEB06269.1 - 0.24 11.5 2.6 8 6.7 0.4 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Ribosomal_S27e PF01667.12 EEB06269.1 - 0.25 10.9 1.2 0.43 10.1 0.8 1.6 1 1 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_6 PF14599.1 EEB06269.1 - 0.36 10.6 2.3 1.5 8.6 1.6 1.8 1 1 1 2 2 2 0 Zinc-ribbon zf-trcl PF13451.1 EEB06269.1 - 0.4 10.3 3.2 6.5 6.4 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain Mu-like_Com PF10122.4 EEB06269.1 - 0.82 8.7 4.7 8.8 5.4 1.2 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Zn_ribbon_recom PF13408.1 EEB06269.1 - 1 9.6 7.3 1.1 9.5 1.3 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L37e PF01907.14 EEB06269.1 - 5.2 6.9 6.2 2.1 8.2 0.8 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e DNA_methylase PF00145.12 EEB06270.1 - 1.8e-42 145.6 0.0 9e-42 143.3 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EEB06270.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEB06270.1 - 0.031 14.8 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain JmjC PF02373.17 EEB06270.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Methyltransf_31 PF13847.1 EEB06270.1 - 0.1 12.1 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 EEB06270.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein OB_NTP_bind PF07717.11 EEB06271.2 - 1.2e-28 99.2 0.0 3.9e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEB06271.2 - 9.4e-24 83.3 1.3 3.3e-23 81.6 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEB06271.2 - 1.5e-13 50.3 0.0 5.1e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB06271.2 - 2.1e-07 30.6 0.0 4.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB06271.2 - 1.3e-05 25.3 0.0 0.00012 22.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEB06271.2 - 0.0075 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EEB06271.2 - 0.0092 15.5 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EEB06271.2 - 0.016 15.0 4.1 2.5 7.8 0.1 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EEB06271.2 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.17 EEB06271.2 - 0.025 14.0 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EEB06271.2 - 0.12 12.1 0.1 0.35 10.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain phiKZ_IP PF12699.2 EEB06272.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins LsmAD PF06741.8 EEB06273.2 - 7.6e-28 96.4 0.9 7.6e-28 96.4 0.6 2.1 2 0 0 2 2 2 1 LsmAD domain DUF202 PF02656.10 EEB06274.1 - 2.5e-13 50.0 2.4 2.5e-13 50.0 1.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) WD40 PF00400.27 EEB06275.1 - 1.5e-50 167.3 9.8 6.7e-14 51.1 0.2 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EEB06275.1 - 5.1e-05 23.0 0.8 0.039 13.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEB06275.1 - 0.00027 19.2 6.6 0.46 8.5 0.1 4.6 2 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB06275.1 - 0.0003 19.6 0.2 0.85 8.2 0.0 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 EEB06275.1 - 0.0059 16.0 0.0 0.018 14.4 0.0 1.7 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EEB06275.1 - 0.0065 14.8 0.0 1 7.5 0.0 2.3 2 1 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 EEB06275.1 - 0.012 14.8 0.3 1.6 7.9 0.0 3.3 1 1 2 3 3 3 0 TUP1-like enhancer of split DUF3312 PF11768.3 EEB06275.1 - 0.061 11.5 0.0 0.17 10.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Methyltransf_23 PF13489.1 EEB06276.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB06276.1 - 0.0049 17.3 0.0 0.044 14.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB06276.1 - 0.016 15.5 0.4 0.33 11.3 0.3 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEB06276.1 - 0.057 13.0 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEB06276.1 - 0.077 13.5 0.0 0.43 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Reprolysin_5 PF13688.1 EEB06277.1 - 1.2e-27 97.1 0.0 1.2e-27 97.1 0.0 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EEB06277.1 - 1.7e-20 73.8 0.0 1e-19 71.2 0.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EEB06277.1 - 5.5e-20 71.3 31.0 5.5e-20 71.3 21.5 3.8 3 1 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.1 EEB06277.1 - 6.3e-19 68.3 0.0 9.1e-17 61.2 0.0 2.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 EEB06277.1 - 4.4e-09 36.2 1.2 4.4e-09 36.2 0.8 2.9 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 EEB06277.1 - 1.1e-07 32.4 0.1 2.8e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EEB06277.1 - 0.0011 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Ribosomal_L3 PF00297.17 EEB06278.1 - 4.4e-122 406.5 7.0 5.1e-122 406.3 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NUC173 PF08161.7 EEB06279.1 - 2.6e-61 206.4 0.6 1.6e-59 200.5 0.0 3.5 4 0 0 4 4 4 1 NUC173 domain Ipi1_N PF12333.3 EEB06279.1 - 0.12 12.3 17.1 3.1 7.8 0.3 6.8 7 2 1 8 8 8 0 Rix1 complex component involved in 60S ribosome maturation PX PF00787.19 EEB06281.1 - 8.7e-17 60.9 0.4 1.7e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EEB06281.1 - 2e-09 36.9 1.6 4.6e-09 35.8 1.1 1.6 1 0 0 1 1 1 1 SNARE domain PHD PF00628.24 EEB06282.1 - 2.5e-12 46.3 5.6 2.5e-12 46.3 3.9 2.0 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 EEB06282.1 - 0.2 11.0 6.3 1.7 8.0 0.1 3.2 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain Uds1 PF15456.1 EEB06282.1 - 0.62 10.0 12.5 0.12 12.3 0.9 2.6 3 0 0 3 3 3 0 Up-regulated During Septation DUF1295 PF06966.7 EEB06283.1 - 2e-49 168.0 10.3 2.4e-49 167.7 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NAF PF03822.9 EEB06283.1 - 0.06 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 NAF domain ICMT PF04140.9 EEB06283.1 - 0.087 13.0 0.0 0.087 13.0 0.0 2.6 4 0 0 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CRPA PF05745.6 EEB06283.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) LSM PF01423.17 EEB06284.1 - 3.4e-17 61.7 0.8 3.9e-17 61.5 0.5 1.0 1 0 0 1 1 1 1 LSM domain DUF2435 PF10363.4 EEB06285.2 - 8e-23 80.1 2.7 2.8e-22 78.4 0.1 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 EEB06285.2 - 4.4e-10 39.7 3.0 0.00024 21.3 1.0 4.3 4 1 1 5 5 5 2 HEAT repeats MMS19_N PF14500.1 EEB06285.2 - 2.4e-05 23.7 1.4 0.12 11.5 0.1 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II UNC45-central PF11701.3 EEB06285.2 - 0.0014 18.2 0.0 0.19 11.3 0.0 3.9 2 2 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT PF02985.17 EEB06285.2 - 0.0052 16.7 3.6 1.3 9.2 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat DUF2411 PF10304.4 EEB06285.2 - 0.054 13.0 0.1 0.49 10.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) GRAM PF02893.15 EEB06286.1 - 2.7e-19 68.4 0.1 5e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain HORMA PF02301.13 EEB06287.1 - 5.4e-44 150.1 0.5 6.1e-44 149.9 0.3 1.0 1 0 0 1 1 1 1 HORMA domain VWA_3 PF13768.1 EEB06287.1 - 0.029 14.0 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain SspB PF04386.8 EEB06287.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 1 1 0 1 1 1 0 Stringent starvation protein B NRDE-2 PF08424.5 EEB06288.1 - 1.2e-59 201.8 0.4 1.2e-59 201.8 0.3 2.7 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EEB06288.1 - 0.004 17.2 2.3 1.2 9.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Nse4_C PF08743.5 EEB06289.1 - 2.9e-29 100.9 0.0 6.6e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EEB06289.1 - 7.2e-09 35.3 0.1 1.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE APG12 PF04110.8 EEB06289.1 - 0.25 11.5 2.0 0.47 10.6 0.1 2.2 2 1 1 3 3 3 0 Ubiquitin-like autophagy protein Apg12 IFRD PF05004.8 EEB06290.1 - 7.9e-30 103.9 11.0 1e-29 103.6 7.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EEB06290.1 - 0.011 16.0 0.3 0.047 13.9 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats Hom_end PF05204.9 EEB06290.1 - 0.66 9.9 0.0 0.66 9.9 0.0 2.5 3 0 0 3 3 3 0 Homing endonuclease DUF1741 PF08427.5 EEB06291.1 - 3.3e-25 88.9 0.6 7.5e-25 87.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MFS_1 PF07690.11 EEB06292.2 - 1.6e-32 112.6 50.1 1.8e-31 109.1 31.1 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB06292.2 - 3.2e-15 55.3 15.7 5.6e-15 54.5 10.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEB06292.2 - 4.1e-13 48.7 11.5 4.1e-13 48.7 8.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter LTV PF04180.9 EEB06294.2 - 1.6e-102 344.1 20.1 5.1e-102 342.5 13.9 1.6 1 1 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EEB06295.2 - 6.7e-18 64.7 0.0 1.6e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB06295.2 - 1.7e-08 33.8 0.0 1.8e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB06295.2 - 0.00019 21.2 1.7 0.059 13.1 0.0 2.7 3 0 0 3 3 3 2 Dynamin family DUF258 PF03193.11 EEB06295.2 - 0.00019 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEB06295.2 - 0.0079 16.6 0.7 0.12 12.8 0.1 2.8 1 1 1 2 2 2 1 Miro-like protein AIG1 PF04548.11 EEB06295.2 - 0.035 13.1 1.4 0.044 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Paralemmin PF03285.10 EEB06296.1 - 0.013 15.0 0.8 0.013 15.0 0.5 2.0 2 0 0 2 2 2 0 Paralemmin RseA_C PF03873.8 EEB06296.1 - 0.14 12.0 1.1 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain Spo12 PF05032.7 EEB06297.1 - 2.5e-16 58.9 2.1 2.5e-16 58.9 1.5 2.2 2 1 0 2 2 2 1 Spo12 family UBA PF00627.26 EEB06298.1 - 1.8e-06 27.5 0.1 4.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EEB06298.1 - 0.01 15.3 0.3 0.059 12.9 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain HLH PF00010.21 EEB06299.1 - 2.5e-12 46.2 1.3 6.2e-12 45.0 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3441 PF11923.3 EEB06299.1 - 0.0091 15.5 0.4 0.017 14.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) APG6 PF04111.7 EEB06299.1 - 0.098 11.6 8.8 0.13 11.3 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 EEB06299.1 - 0.93 9.8 6.2 2.4 8.4 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) ABC_membrane PF00664.18 EEB06300.1 - 1.3e-93 313.4 31.5 1.7e-48 165.4 11.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEB06300.1 - 1e-50 171.6 0.2 6.3e-30 104.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EEB06300.1 - 1.4e-11 44.0 0.0 0.0016 17.7 0.0 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEB06300.1 - 7.6e-07 29.3 0.1 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EEB06300.1 - 2.2e-06 27.5 0.0 0.084 12.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EEB06300.1 - 3e-06 26.4 0.2 0.0094 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEB06300.1 - 4e-06 26.2 0.2 0.056 12.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEB06300.1 - 2.4e-05 24.4 9.0 0.9 9.4 0.1 5.2 4 2 0 5 5 4 1 AAA domain AAA_23 PF13476.1 EEB06300.1 - 3e-05 24.4 0.8 0.12 12.7 0.1 3.0 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EEB06300.1 - 0.00023 21.6 0.0 1 9.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 EEB06300.1 - 0.0011 18.4 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEB06300.1 - 0.0039 16.7 1.2 1.8 8.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain Dynamin_N PF00350.18 EEB06300.1 - 0.0062 16.3 1.2 0.35 10.6 0.0 3.0 3 0 0 3 3 3 1 Dynamin family T2SE PF00437.15 EEB06300.1 - 0.0073 15.2 0.0 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EEB06300.1 - 0.0082 15.9 0.4 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EEB06300.1 - 0.01 15.9 0.3 4.8 7.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEB06300.1 - 0.016 14.6 0.2 6.2 6.1 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EEB06300.1 - 0.021 13.9 0.3 6.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EEB06300.1 - 0.021 14.2 0.1 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEB06300.1 - 0.023 15.5 0.1 0.24 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEB06300.1 - 0.026 14.2 0.2 15 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EEB06300.1 - 0.034 13.0 0.4 4 6.1 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain ArgK PF03308.11 EEB06300.1 - 0.055 12.2 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EEB06300.1 - 0.064 13.5 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEB06300.1 - 0.074 13.2 0.1 4.7 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 EEB06300.1 - 0.11 11.8 1.0 9.1 5.6 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EEB06300.1 - 0.12 11.7 0.3 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EEB06300.1 - 0.15 11.5 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EEB06300.1 - 0.19 11.4 0.7 7.5 6.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EEB06300.1 - 0.2 11.3 1.1 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain STE3 PF02076.10 EEB06301.1 - 1.1e-60 205.1 18.6 1.4e-60 204.7 12.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor His_biosynth PF00977.16 EEB06302.2 - 3.6e-31 108.2 0.1 3.8e-30 104.8 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EEB06302.2 - 0.035 13.2 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4602 PF15375.1 EEB06303.1 - 0.02 14.9 14.9 0.069 13.2 10.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) RNR_inhib PF08591.5 EEB06304.1 - 6e-05 23.8 0.0 8.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Erf4 PF10256.4 EEB06305.1 - 1.8e-25 89.0 0.0 2.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Init_tRNA_PT PF04179.7 EEB06306.1 - 9.3e-127 423.6 0.0 1.1e-126 423.3 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase T5orf172 PF10544.4 EEB06307.1 - 1.3e-10 41.5 0.4 2.8e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EEB06307.1 - 5.8e-08 33.0 1.5 8.8e-08 32.5 0.4 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 GSH_synth_ATP PF03917.12 EEB06308.2 - 2.5e-125 417.9 0.6 2.9e-125 417.7 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EEB06308.2 - 1.6e-32 111.6 0.1 5.6e-32 109.9 0.1 1.9 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Pro-kuma_activ PF09286.6 EEB06308.2 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain tRNA-synt_2b PF00587.20 EEB06309.1 - 5.8e-68 227.8 0.2 1e-67 227.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEB06309.1 - 7.6e-23 80.2 0.0 2e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF1654 PF07867.6 EEB06309.1 - 0.097 12.0 0.1 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) TrkH PF02386.11 EEB06310.1 - 1e-123 412.4 24.7 5.5e-120 400.1 13.5 2.1 2 0 0 2 2 2 2 Cation transport protein MCM PF00493.18 EEB06311.1 - 1.5e-143 477.6 0.4 1.9e-143 477.2 0.3 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEB06311.1 - 5.7e-23 81.7 0.5 1.5e-22 80.3 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEB06311.1 - 2.8e-05 23.3 0.0 0.0011 18.1 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEB06311.1 - 4.1e-05 23.3 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEB06311.1 - 0.00049 19.6 0.1 0.0029 17.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEB06311.1 - 0.046 13.1 0.0 0.72 9.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain COX5A PF02284.11 EEB06312.2 - 7.4e-32 109.5 0.0 9.2e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 EEB06313.2 - 4.7e-47 160.4 16.6 5.3e-47 160.2 11.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mito_carr PF00153.22 EEB06314.1 - 1.1e-12 47.4 1.4 0.015 14.9 0.0 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein FAM176 PF14851.1 EEB06314.1 - 0.096 12.3 2.1 0.16 11.6 1.5 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EEB06314.1 - 0.19 10.7 3.8 0.29 10.0 2.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 EEB06314.1 - 0.5 8.4 1.6 0.71 7.9 1.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2457 PF10446.4 EEB06314.1 - 2 7.0 10.5 2.7 6.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CRM1_C PF08767.6 EEB06315.1 - 3.1e-131 437.0 1.8 3.1e-131 437.0 1.3 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EEB06315.1 - 5.6e-42 143.1 14.4 1.6e-40 138.4 4.8 5.0 4 1 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 EEB06315.1 - 7e-14 51.5 2.0 1.3e-13 50.6 0.3 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain PNP_UDP_1 PF01048.15 EEB06316.1 - 2.1e-44 151.2 0.2 2.6e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HECT PF00632.20 EEB06317.1 - 3.6e-87 292.4 0.0 6.3e-87 291.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEB06317.1 - 6.3e-12 45.1 6.8 5.9e-09 35.6 0.3 2.9 2 0 0 2 2 2 2 WW domain C2 PF00168.25 EEB06317.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 C2 domain ADH_zinc_N PF00107.21 EEB06319.2 - 5.3e-20 71.2 0.0 1.4e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB06319.2 - 1.4e-07 32.4 0.0 4.5e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Transferase PF02458.10 EEB06320.1 - 4.3e-28 97.9 0.0 1.8e-25 89.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family Ribosomal_L14e PF01929.12 EEB06321.1 - 2.7e-29 101.3 0.9 3.6e-29 100.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EEB06321.1 - 0.00054 19.5 1.1 0.00054 19.5 0.8 1.8 2 0 0 2 2 2 1 KOW motif ubiquitin PF00240.18 EEB06322.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEB06322.1 - 8.5e-31 105.3 11.3 1.3e-30 104.6 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEB06322.1 - 4.1e-20 71.2 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB06322.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB06322.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB06322.1 - 0.007 16.2 0.1 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEB06322.1 - 0.011 15.9 0.1 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEB06322.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EEB06322.1 - 0.19 11.5 1.9 0.87 9.4 1.3 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S26e PF01283.14 EEB06323.1 - 6.7e-53 177.7 8.6 7.6e-53 177.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EEB06323.1 - 0.26 11.7 2.8 1.5 9.2 1.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEB06323.1 - 0.52 10.1 4.7 0.92 9.3 1.1 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Formyl_trans_N PF00551.14 EEB06325.1 - 9.6e-26 90.4 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EEB06325.1 - 1.8e-07 31.1 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Alba PF01918.16 EEB06326.1 - 1.9e-05 24.1 0.4 2.7e-05 23.6 0.3 1.2 1 0 0 1 1 1 1 Alba Tctex-1 PF03645.8 EEB06327.1 - 1.1e-14 54.0 0.0 1.3e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family BiPBP_C PF06832.7 EEB06327.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.4 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DASH_Dad2 PF08654.5 EEB06328.1 - 4.6e-20 71.5 0.2 5.2e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 ALAD PF00490.16 EEB06329.1 - 2.2e-119 398.1 0.0 2.7e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 EEB06330.1 - 6e-32 110.8 0.0 9.5e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06330.1 - 7.5e-10 38.3 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 EEB06330.1 - 0.28 10.1 0.5 0.42 9.5 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleoporin_C PF03177.9 EEB06331.2 - 5.1e-70 236.6 24.7 6.7e-70 236.2 17.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEB06331.2 - 1.7e-27 96.2 0.0 3.2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like TRM13 PF05206.9 EEB06332.1 - 3.7e-68 229.5 0.0 4.7e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 EEB06332.1 - 6.9e-07 28.8 0.1 6.9e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EEB06332.1 - 8.7e-05 22.2 0.3 0.00019 21.1 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 EEB06333.1 - 2.4e-58 197.3 0.0 4.4e-58 196.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06333.1 - 1e-23 83.7 0.0 1.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06333.1 - 4.4e-09 35.6 0.0 7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB06333.1 - 0.00041 19.4 0.0 0.00083 18.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB06333.1 - 0.00053 19.7 0.2 0.0042 16.8 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Rif1_N PF12231.3 EEB06334.1 - 2.9e-103 345.7 6.9 5.1e-103 344.9 4.8 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal TPP1 PF10341.4 EEB06335.1 - 7.7e-13 48.3 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD FAM216B PF15107.1 EEB06335.1 - 0.00055 19.8 0.2 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 FAM216B protein family Ras PF00071.17 EEB06336.2 - 4.2e-55 185.5 0.0 5.6e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB06336.2 - 2.1e-17 63.7 0.0 4.4e-17 62.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEB06336.2 - 1.8e-10 40.3 0.0 2.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB06336.2 - 1.5e-06 27.7 0.0 2.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEB06336.2 - 0.00098 19.0 0.0 0.0015 18.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEB06336.2 - 0.022 14.7 0.1 0.059 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EEB06336.2 - 0.069 12.4 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4248 PF14053.1 EEB06336.2 - 0.14 11.7 0.7 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF4187 PF13821.1 EEB06337.1 - 8.3e-17 60.5 0.5 8.3e-17 60.5 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EEB06337.1 - 2.8e-07 30.1 0.2 5.1e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Baculo_p24 PF05073.7 EEB06337.1 - 0.052 13.1 0.5 0.07 12.6 0.4 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein G-patch_2 PF12656.2 EEB06337.1 - 0.44 10.4 3.9 0.18 11.6 0.3 2.2 2 0 0 2 2 2 0 DExH-box splicing factor binding site DUF726 PF05277.7 EEB06338.1 - 1.3e-120 402.4 0.5 1.7e-120 402.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EEB06338.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PX PF00787.19 EEB06339.1 - 2e-22 79.0 1.3 4.8e-22 77.8 0.1 2.2 2 0 0 2 2 2 1 PX domain GAS PF13851.1 EEB06339.1 - 0.0015 17.8 14.5 0.0036 16.5 1.4 2.4 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding USP8_dimer PF08969.6 EEB06339.1 - 0.0031 17.4 0.9 0.011 15.6 0.6 2.0 1 0 0 1 1 1 1 USP8 dimerisation domain DASH_Dad1 PF08649.5 EEB06339.1 - 0.0064 16.1 2.3 0.035 13.8 0.2 2.6 2 0 0 2 2 2 1 DASH complex subunit Dad1 zf-C4H2 PF10146.4 EEB06339.1 - 0.049 13.6 13.2 1.4 8.9 4.1 2.8 3 0 0 3 3 3 0 Zinc finger-containing protein PilJ PF13675.1 EEB06339.1 - 0.054 13.8 8.3 1.1 9.5 0.1 3.4 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 EEB06339.1 - 0.078 13.1 13.7 0.62 10.2 2.0 3.6 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Polysacc_deac_1 PF01522.16 EEB06339.1 - 0.14 11.7 0.1 0.44 10.1 0.1 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF479 PF04336.7 EEB06339.1 - 0.37 10.9 6.8 0.087 12.9 0.7 2.8 3 1 0 3 3 2 0 Protein of unknown function, DUF479 Erp_C PF06780.6 EEB06339.1 - 0.54 10.0 8.2 0.08 12.7 0.4 3.0 3 1 0 3 3 3 0 Erp protein C-terminus FlaC_arch PF05377.6 EEB06339.1 - 1.3 8.9 6.6 2.5 8.0 0.3 3.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Sugarporin_N PF11471.3 EEB06339.1 - 2.7 7.7 6.8 0.52 9.9 0.1 3.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Vps5 PF09325.5 EEB06339.1 - 7.8 5.6 19.4 6.5 5.9 4.1 2.5 1 1 1 2 2 2 0 Vps5 C terminal like Phos_pyr_kin PF08543.7 EEB06340.1 - 1.5e-17 63.6 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEB06340.1 - 2.9e-09 36.4 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase P34-Arc PF04045.9 EEB06341.1 - 2e-98 328.5 2.3 2.4e-98 328.2 1.6 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc NuA4 PF09340.5 EEB06342.1 - 3.3e-25 87.5 1.1 3.3e-25 87.5 0.8 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 CALCOCO1 PF07888.6 EEB06342.1 - 0.0056 15.0 0.1 0.006 14.9 0.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AATF-Che1 PF13339.1 EEB06342.1 - 0.11 12.6 2.4 0.41 10.7 1.6 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor RabGAP-TBC PF00566.13 EEB06343.1 - 4.3e-41 140.7 0.1 6.7e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BaffR-Tall_bind PF09256.5 EEB06343.1 - 0.083 12.4 0.3 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Ribosomal_S13_N PF08069.7 EEB06344.1 - 1.6e-28 98.2 0.2 3.7e-28 97.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEB06344.1 - 2.1e-24 85.1 0.1 3.2e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Rax2 PF12768.2 EEB06345.2 - 1.7e-32 112.7 31.2 4e-30 104.9 2.7 6.4 4 2 3 7 7 7 4 Cortical protein marker for cell polarity Kelch_4 PF13418.1 EEB06345.2 - 0.00084 19.0 4.3 2.8 7.7 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EEB06345.2 - 0.049 13.4 1.8 1 9.2 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 EEB06345.2 - 1 9.6 9.0 29 5.0 0.0 5.6 6 0 0 6 6 6 0 Kelch motif DAD PF02109.11 EEB06346.1 - 5.2e-38 129.5 7.1 6.3e-38 129.3 4.9 1.0 1 0 0 1 1 1 1 DAD family DUF814 PF05670.8 EEB06347.2 - 3.4e-06 26.8 0.4 2.1e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF814) NGP1NT PF08153.7 EEB06348.2 - 6.2e-49 165.2 0.1 9.6e-49 164.6 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EEB06348.2 - 1.1e-18 67.3 0.0 2.8e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 EEB06348.2 - 8.1e-06 25.1 0.1 0.025 13.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 EEB06348.2 - 5.6e-05 22.4 0.0 0.00065 19.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB06348.2 - 5.9e-05 22.9 0.2 0.047 13.5 0.0 3.6 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 EEB06348.2 - 0.00066 19.1 0.0 0.23 10.8 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEB06348.2 - 0.0053 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEB06348.2 - 0.13 12.7 0.2 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein LRR_6 PF13516.1 EEB06349.1 - 9.7e-06 25.1 4.4 0.033 14.2 0.0 5.5 4 1 1 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 EEB06349.1 - 0.00086 18.8 10.4 0.43 10.2 0.2 4.9 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EEB06349.1 - 0.0075 16.2 0.2 7.4 7.2 0.0 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_8 PF13855.1 EEB06349.1 - 0.5 10.1 6.5 18 5.1 0.4 4.0 3 1 0 3 3 3 0 Leucine rich repeat Ion_trans PF00520.26 EEB06350.2 - 2.9e-66 222.5 80.6 3.4e-25 88.4 4.8 6.2 4 2 2 6 6 6 5 Ion transport protein PKD_channel PF08016.7 EEB06350.2 - 0.0023 16.4 6.3 0.0023 16.4 4.3 7.1 5 2 2 7 7 7 6 Polycystin cation channel V-ATPase_C PF03223.10 EEB06353.1 - 5.6e-111 371.0 3.0 6.3e-111 370.8 2.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C E1-E2_ATPase PF00122.15 EEB06354.2 - 8.3e-56 188.5 0.3 8.3e-56 188.5 0.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEB06354.2 - 4.4e-43 146.9 10.7 4.4e-43 146.9 7.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEB06354.2 - 2.2e-25 90.3 0.0 9.3e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB06354.2 - 4.7e-14 53.0 0.0 1.2e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB06354.2 - 1.3e-13 50.7 0.0 2.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEB06354.2 - 1.2e-07 31.5 0.3 3e-05 23.7 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEB06354.2 - 1.8e-07 30.5 0.0 5.8e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus YjgP_YjgQ PF03739.9 EEB06354.2 - 0.0058 15.4 0.3 0.0058 15.4 0.2 2.7 3 0 0 3 3 3 1 Predicted permease YjgP/YjgQ family Cyclin_N PF00134.18 EEB06355.1 - 9.5e-45 151.2 0.1 1.1e-41 141.2 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB06355.1 - 7.9e-27 93.5 0.1 1.4e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain BCDHK_Adom3 PF10436.4 EEB06356.1 - 1.4e-45 154.7 0.0 2e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEB06356.1 - 4.6e-18 64.9 0.0 9e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEB06356.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med11 PF10280.4 EEB06357.1 - 2.3e-10 40.5 0.5 2.7e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Mediator complex protein Ala_racemase_N PF01168.15 EEB06358.1 - 6.6e-48 163.1 0.0 7.9e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HAD_2 PF13419.1 EEB06359.1 - 8.2e-27 94.5 0.0 1e-26 94.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Regulator_TrmB PF11495.3 EEB06359.1 - 0.16 10.9 0.0 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB BCS1_N PF08740.6 EEB06360.1 - 8.2e-49 165.7 0.1 1.1e-48 165.3 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEB06360.1 - 3.4e-19 69.3 0.0 1e-18 67.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEB06360.1 - 6e-05 23.8 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEB06360.1 - 0.00097 18.5 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB06360.1 - 0.0036 17.6 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEB06360.1 - 0.0063 16.5 0.1 0.026 14.4 0.0 2.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEB06360.1 - 0.01 15.5 0.1 0.18 11.6 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 EEB06360.1 - 0.011 15.2 0.2 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEB06360.1 - 0.018 15.2 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EEB06360.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEB06360.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEB06360.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEB06360.1 - 0.039 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 EEB06360.1 - 0.044 12.8 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EEB06360.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EEB06360.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SLAC1 PF03595.12 EEB06361.1 - 5.5e-72 242.1 56.1 6.4e-72 241.9 38.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel E1_DerP2_DerF2 PF02221.10 EEB06362.1 - 1.3e-17 64.3 0.1 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EEB06362.1 - 0.00099 19.1 0.1 0.0031 17.5 0.0 1.7 1 1 0 1 1 1 1 ML-like domain Myb_Cef PF11831.3 EEB06363.2 - 1e-37 129.5 9.6 1e-37 129.5 6.7 3.5 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EEB06363.2 - 2.4e-22 78.7 5.8 1.7e-11 43.9 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB06363.2 - 5.8e-19 67.9 9.1 2.2e-13 50.0 2.7 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain ATC_hydrolase PF14196.1 EEB06363.2 - 4.9 7.5 7.5 19 5.6 0.8 3.2 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Yip1 PF04893.12 EEB06364.1 - 1.2e-11 44.4 13.2 1.6e-11 44.0 9.2 1.3 1 1 0 1 1 1 1 Yip1 domain Claudin_2 PF13903.1 EEB06364.1 - 4.7 6.8 10.1 1.9 8.1 2.1 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Rad51 PF08423.6 EEB06365.1 - 3.5e-139 461.9 0.0 4.4e-139 461.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEB06365.1 - 6.6e-15 55.0 0.1 1.6e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 EEB06365.1 - 6.4e-11 41.8 0.0 9.1e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EEB06365.1 - 4.4e-10 39.5 0.1 2.7e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain KaiC PF06745.8 EEB06365.1 - 7.1e-07 28.5 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 EEB06365.1 - 0.061 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Ribosomal_60s PF00428.14 EEB06366.1 - 2.3e-26 92.0 12.7 2.9e-26 91.6 8.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CSTF2_hinge PF14327.1 EEB06367.1 - 4.4e-21 74.7 0.5 4.4e-21 74.7 0.3 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EEB06367.1 - 1.1e-19 69.7 0.0 1.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06367.1 - 2.9e-11 43.1 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EEB06367.1 - 8.2e-10 37.8 7.3 1.5e-09 36.9 5.0 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EEB06367.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L3 PF00297.17 EEB06368.1 - 4.3e-36 124.6 2.8 1.5e-34 119.5 2.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 NQRA_SLBB PF11973.3 EEB06368.1 - 0.085 13.1 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 NQRA C-terminal domain ADH_N PF08240.7 EEB06369.1 - 4.3e-35 119.7 0.8 8.7e-35 118.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB06369.1 - 5e-26 90.7 0.3 7.5e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB06369.1 - 0.00022 22.1 0.0 0.00041 21.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RuBisCO_large PF00016.15 EEB06369.1 - 0.079 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain TRAPP PF04051.11 EEB06370.1 - 8.2e-32 109.8 0.0 1e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component AA_kinase PF00696.23 EEB06370.1 - 0.098 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Amino acid kinase family PIG-L PF02585.12 EEB06371.1 - 2.6e-24 86.1 0.0 4.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glutaredoxin PF00462.19 EEB06372.1 - 1.8e-15 56.6 0.0 5e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin zf-CSL PF05207.8 EEB06373.1 - 3.8e-25 87.1 1.1 5.9e-25 86.5 0.7 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EEB06373.1 - 0.014 15.3 0.2 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EEB06373.1 - 0.025 14.1 0.4 0.036 13.6 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEB06373.1 - 0.039 13.6 0.4 0.063 12.9 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 EEB06373.1 - 0.073 12.9 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-RING_4 PF14570.1 EEB06373.1 - 0.29 10.7 1.8 0.57 9.8 1.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MutS_V PF00488.16 EEB06374.1 - 4.3e-75 252.1 0.0 6.8e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEB06374.1 - 4e-36 124.7 0.5 7.4e-36 123.8 0.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEB06374.1 - 1.6e-27 95.7 0.0 3.3e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEB06374.1 - 6.2e-10 39.2 0.1 6.8e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EEB06374.1 - 1e-07 32.0 0.1 2.8e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV Ribosomal_L1 PF00687.16 EEB06375.1 - 8.4e-51 172.4 0.7 8.4e-51 172.4 0.5 1.8 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2201_N PF13203.1 EEB06375.1 - 0.0044 16.2 6.4 0.0069 15.6 4.4 1.3 1 0 0 1 1 1 1 Putative metallopeptidase domain Tfb4 PF03850.9 EEB06375.1 - 0.25 10.5 3.1 0.42 9.8 2.1 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 Brr6_like_C_C PF10104.4 EEB06377.1 - 4.3e-37 126.6 4.3 6.9e-37 125.9 3.0 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Mem_trans PF03547.13 EEB06377.1 - 0.026 12.8 0.2 0.026 12.8 0.1 1.5 2 0 0 2 2 2 0 Membrane transport protein CDC45 PF02724.9 EEB06377.1 - 0.63 7.9 5.5 0.88 7.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein MDFI PF15316.1 EEB06377.1 - 0.64 9.9 3.0 5.1 7.0 2.1 2.1 1 1 0 1 1 1 0 MyoD family inhibitor Nucleocapsid-N PF11030.3 EEB06377.1 - 3.8 7.2 12.4 5.5 6.7 8.6 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N Pkinase PF00069.20 EEB06378.2 - 2.9e-42 144.6 0.2 2.7e-24 85.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06378.2 - 4e-13 49.0 0.0 2e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEB06378.2 - 0.047 13.4 0.2 0.31 10.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 EEB06380.2 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEB06380.2 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EEB06380.2 - 0.00019 20.2 0.2 0.0023 16.7 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.13 EEB06380.2 - 0.019 14.2 0.0 0.077 12.2 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EEB06380.2 - 0.023 13.5 0.0 0.048 12.5 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EEB06380.2 - 0.043 12.6 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Methyltransf_16 PF10294.4 EEB06381.1 - 1.8e-18 66.6 0.0 2.3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEB06381.1 - 0.00034 21.1 0.0 0.00057 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EEB06381.1 - 0.0015 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.8 EEB06381.1 - 0.0048 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEB06381.1 - 0.014 14.8 0.1 0.066 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EEB06381.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEB06381.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.1 EEB06381.1 - 0.15 11.6 0.1 0.43 10.1 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain PS_pyruv_trans PF04230.8 EEB06382.1 - 8.3e-25 88.0 0.3 4.1e-24 85.7 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase SR-25 PF10500.4 EEB06382.1 - 4.4 6.7 12.4 7.1 6.0 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_20 PF00982.16 EEB06383.1 - 1.5e-156 521.5 0.9 2e-156 521.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEB06383.1 - 2.5e-36 124.7 0.0 3.7e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase MBA1 PF07961.6 EEB06383.1 - 0.042 12.7 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 MBA1-like protein SURF2 PF05477.6 EEB06383.1 - 0.68 9.0 5.8 2.4 7.2 0.1 2.7 3 1 0 3 3 3 0 Surfeit locus protein 2 (SURF2) CPDase PF07823.6 EEB06384.1 - 2e-25 89.4 0.0 2.3e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EEB06384.1 - 0.0034 17.0 0.1 0.1 12.3 0.1 2.0 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily BRCT PF00533.21 EEB06385.2 - 5e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Peptidase_M16 PF00675.15 EEB06386.1 - 2.3e-37 128.0 0.0 1e-36 125.9 0.0 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEB06386.1 - 2.6e-33 115.2 0.1 9.1e-20 71.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Syd PF07348.7 EEB06386.1 - 0.05 12.9 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 Syd protein (SUKH-2) Methyltransf_25 PF13649.1 EEB06386.1 - 0.055 13.8 0.2 0.96 9.8 0.1 2.8 2 0 0 2 2 2 0 Methyltransferase domain MPP6 PF10175.4 EEB06387.1 - 1.4e-05 25.4 0.2 1.4e-05 25.4 0.2 1.7 2 0 0 2 2 2 1 M-phase phosphoprotein 6 CDC45 PF02724.9 EEB06387.1 - 8.1 4.3 12.1 10 4.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein 2-Hacid_dh_C PF02826.14 EEB06388.1 - 1.5e-57 193.5 0.0 2e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEB06388.1 - 3.4e-18 65.3 0.0 4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEB06388.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEB06388.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AHH PF14412.1 EEB06388.1 - 0.064 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DBR1 PF05011.8 EEB06389.1 - 3.1e-36 124.4 0.2 5.2e-36 123.6 0.2 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EEB06389.1 - 1.2e-16 60.7 0.3 1.6e-16 60.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EEB06389.1 - 0.0005 19.3 0.0 0.004 16.3 0.0 2.2 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Methyltransf_23 PF13489.1 EEB06390.1 - 2.4e-10 40.3 0.0 5.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB06390.1 - 7.7e-07 29.6 0.0 1.8e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EEB06390.1 - 4.6e-06 25.9 0.0 7.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 EEB06390.1 - 8.2e-06 25.4 0.0 0.0049 16.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Rhodanese PF00581.15 EEB06390.1 - 0.00038 20.7 0.0 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain MTS PF05175.9 EEB06390.1 - 0.0012 18.2 0.0 0.0095 15.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEB06390.1 - 0.0015 18.8 0.0 0.0038 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB06390.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEB06390.1 - 0.0045 16.0 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase TPMT PF05724.6 EEB06390.1 - 0.0059 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 EEB06390.1 - 0.01 16.2 0.0 0.033 14.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEB06390.1 - 0.024 15.1 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EEB06390.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EEB06390.1 - 0.09 12.3 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) MetW PF07021.7 EEB06390.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 EEB06390.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Hydrolase PF00702.21 EEB06391.1 - 1.9e-24 87.2 0.0 8.9e-24 85.0 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB06391.1 - 5.5e-23 82.1 0.0 1.1e-22 81.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEB06391.1 - 2.1e-19 69.4 0.0 5.8e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEB06391.1 - 7.6e-08 32.2 0.1 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEB06391.1 - 0.00024 20.7 0.1 0.0063 16.1 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEB06391.1 - 0.016 14.5 0.3 0.043 13.0 0.1 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SHS2_Rpb7-N PF03876.12 EEB06392.1 - 2.1e-18 66.1 0.0 3.3e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEB06392.1 - 1.7e-11 43.9 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EEB06392.1 - 0.081 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 C2 PF00168.25 EEB06393.1 - 1.6e-50 168.8 1.0 1e-21 76.5 0.0 4.6 4 0 0 4 4 4 4 C2 domain CEP76-C2 PF15627.1 EEB06393.1 - 0.0023 17.4 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 CEP76 C2 domain GTP_EFTU PF00009.22 EEB06395.1 - 5.2e-61 205.3 0.1 7.4e-61 204.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEB06395.1 - 4.1e-35 119.9 0.0 1.1e-34 118.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEB06395.1 - 6.1e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEB06395.1 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEB06395.1 - 3.1e-12 46.4 0.7 1.8e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB06395.1 - 2.7e-05 24.0 0.1 6.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 EEB06395.1 - 0.13 12.0 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 SUKH-4 immunity protein Zn_clus PF00172.13 EEB06396.1 - 3.3e-08 33.2 10.2 6.1e-08 32.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EEB06397.1 - 4.7e-26 90.2 0.0 2.6e-10 39.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06397.1 - 5.6e-17 61.4 0.0 8.7e-09 35.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06397.1 - 3.2e-11 42.8 0.0 7.2e-05 22.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEB06397.1 - 0.0033 17.2 0.1 0.086 12.6 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EEB06397.1 - 0.049 13.4 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EEB06397.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Calcipressin WD40 PF00400.27 EEB06398.1 - 3e-45 150.5 18.1 1.6e-08 34.0 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Gmad1 PF10647.4 EEB06398.1 - 0.0034 16.8 0.3 0.0086 15.5 0.2 1.9 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain LisH PF08513.6 EEB06399.1 - 1e-08 34.6 0.1 2.2e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 LisH TIM21 PF08294.6 EEB06400.1 - 1.1e-31 109.4 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EEB06400.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UDPGP PF01704.13 EEB06401.1 - 5.7e-34 117.3 0.0 7.8e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_L23eN PF03939.8 EEB06401.1 - 0.3 11.1 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain RNA_pol_A_bac PF01000.21 EEB06402.1 - 5.4e-29 100.6 0.0 9e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEB06402.1 - 2.9e-13 48.7 0.0 4.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EMP70 PF02990.11 EEB06403.1 - 5.4e-119 398.0 18.3 7.2e-119 397.5 12.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PPR_1 PF12854.2 EEB06404.2 - 0.0027 17.1 0.2 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 EEB06404.2 - 0.057 13.4 0.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family V-ATPase_G PF03179.10 EEB06405.2 - 2.8e-25 88.6 8.8 3.2e-25 88.4 6.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EEB06405.2 - 0.0097 15.1 10.7 0.098 11.8 1.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) TraC_F_IV PF11130.3 EEB06405.2 - 0.017 14.5 0.1 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer FRD2 PF03197.8 EEB06405.2 - 0.019 15.4 0.5 0.024 15.1 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage FRD2 protein GTP_cyclohydro2 PF00925.15 EEB06405.2 - 0.038 13.2 0.6 0.055 12.7 0.3 1.4 1 1 0 1 1 1 0 GTP cyclohydrolase II ATP-synt_B PF00430.13 EEB06405.2 - 0.052 13.3 9.7 0.28 10.9 6.0 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Tox-MPTase2 PF15638.1 EEB06405.2 - 0.1 12.1 0.9 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 DUF4145 PF13643.1 EEB06405.2 - 0.14 12.0 0.6 0.33 10.8 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) S_layer_C PF05124.7 EEB06405.2 - 0.21 11.1 4.4 0.23 11.0 3.1 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Nop25 PF09805.4 EEB06405.2 - 0.28 11.2 9.0 0.37 10.8 6.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PTPlike_phytase PF14566.1 EEB06405.2 - 0.37 10.8 2.6 0.42 10.6 1.8 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate HrpE PF06188.7 EEB06405.2 - 0.44 10.2 4.4 0.8 9.4 3.1 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Integrin_b_cyt PF08725.6 EEB06405.2 - 0.44 9.9 6.0 3.4 7.1 4.2 2.3 1 1 0 1 1 1 0 Integrin beta cytoplasmic domain Phage_int_SAM_5 PF13102.1 EEB06405.2 - 1.2 9.1 6.7 1.8 8.5 4.6 1.3 1 1 0 1 1 1 0 Phage integrase SAM-like domain DUF883 PF05957.8 EEB06405.2 - 4.4 7.7 7.1 6.2 7.2 1.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SAM_2 PF07647.12 EEB06406.1 - 2.1e-13 49.8 0.0 4.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EEB06406.1 - 2.5e-10 40.4 0.0 6.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EEB06406.1 - 9.7e-10 37.6 0.1 1.7e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB06406.1 - 5.5e-09 35.4 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EEB06406.1 - 5.8e-09 36.1 1.3 3.3e-08 33.7 0.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 EEB06406.1 - 1.6e-08 34.5 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EEB06406.1 - 0.0023 17.9 0.1 0.024 14.7 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EEB06406.1 - 0.0043 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.11 EEB06406.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ras PF00071.17 EEB06407.1 - 3.9e-48 162.8 0.0 4.7e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB06407.1 - 6e-15 55.7 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB06407.1 - 5.9e-11 41.9 0.0 7.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB06407.1 - 0.0002 20.5 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EEB06407.1 - 0.00024 21.2 0.1 0.002 18.2 0.0 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EEB06407.1 - 0.019 13.7 1.7 0.73 8.4 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EEB06407.1 - 0.025 13.8 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EEB06407.1 - 0.047 13.8 0.1 0.18 11.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EEB06407.1 - 0.078 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEB06407.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 EEB06407.1 - 0.15 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 zf-MIZ PF02891.15 EEB06408.1 - 5.2e-12 45.0 0.9 1.2e-11 43.9 0.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Glyco_hydro_42M PF08532.5 EEB06409.2 - 0.0044 16.1 0.1 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain RRM_6 PF14259.1 EEB06410.1 - 1.1e-15 57.3 0.1 2.5e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB06410.1 - 1.4e-12 47.0 0.3 4.8e-05 22.9 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06410.1 - 3.1e-09 36.5 0.0 8.5e-07 28.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.7 EEB06411.1 - 1.4e-09 38.2 15.5 0.013 16.0 0.0 6.9 8 0 0 8 8 7 2 Sel1 repeat TPR_2 PF07719.12 EEB06411.1 - 2e-08 33.5 0.1 2.9e-05 23.6 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEB06411.1 - 1.2e-07 30.9 0.2 9.1e-06 25.0 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06411.1 - 9.7e-06 26.1 10.6 0.0092 16.6 0.2 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06411.1 - 6.7e-05 22.7 1.0 0.0025 17.6 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06411.1 - 8.1e-05 22.1 0.1 0.0087 15.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06411.1 - 0.00017 21.8 4.5 0.042 14.4 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06411.1 - 0.00042 19.8 0.4 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06411.1 - 0.0006 20.1 0.3 0.014 15.8 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EEB06411.1 - 0.0013 18.5 1.9 2 8.3 0.0 3.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 EEB06411.1 - 0.017 15.2 2.4 0.61 10.4 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEB06411.1 - 0.021 14.4 0.0 0.021 14.4 0.0 3.9 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.1 EEB06411.1 - 5.1 7.5 8.1 2 8.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Nop16 PF09420.5 EEB06412.1 - 2.2e-37 128.6 3.5 2.7e-37 128.3 2.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2543 PF10820.3 EEB06412.1 - 0.065 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) R3H PF01424.17 EEB06412.1 - 0.12 12.1 0.1 0.33 10.6 0.0 1.7 1 1 0 1 1 1 0 R3H domain IGPS PF00218.16 EEB06413.1 - 2.4e-96 321.7 0.2 4.3e-96 320.8 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EEB06413.1 - 9.2e-52 175.4 0.1 6.8e-48 162.8 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EEB06413.1 - 7.7e-49 165.7 0.0 1.4e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEB06413.1 - 5.3e-07 29.3 0.0 2.2e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.16 EEB06413.1 - 0.0012 18.2 0.2 0.095 11.9 0.0 2.6 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.14 EEB06413.1 - 0.0036 16.8 3.8 0.026 14.0 0.2 3.2 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain DHO_dh PF01180.16 EEB06413.1 - 0.011 14.7 0.7 0.25 10.2 0.0 2.8 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EEB06413.1 - 0.023 13.5 0.1 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Aldolase PF01081.14 EEB06413.1 - 0.028 13.5 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 KDPG and KHG aldolase Fusion_gly PF00523.13 EEB06413.1 - 0.049 11.6 0.4 0.078 11.0 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 TMP-TENI PF02581.12 EEB06413.1 - 0.049 12.7 0.3 0.49 9.4 0.1 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Arf PF00025.16 EEB06414.1 - 3.1e-74 247.9 0.0 3.6e-74 247.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEB06414.1 - 5e-13 48.7 0.0 5.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEB06414.1 - 2.2e-12 46.4 1.0 1.7e-08 33.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEB06414.1 - 3.1e-12 46.0 0.0 3.7e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEB06414.1 - 1.4e-10 40.6 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEB06414.1 - 1.6e-07 31.8 0.0 2.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEB06414.1 - 0.00015 21.6 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EEB06414.1 - 0.001 18.1 0.4 0.0041 16.2 0.3 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EEB06414.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ADH_N PF08240.7 EEB06415.1 - 4.6e-27 93.9 1.9 4.6e-27 93.9 1.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB06415.1 - 1.5e-22 79.5 0.4 3e-22 78.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEB06415.1 - 0.0018 17.4 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EEB06415.1 - 0.0019 19.0 0.0 0.0038 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EEB06415.1 - 0.0046 16.9 0.1 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EEB06415.1 - 0.02 14.4 1.6 0.3 10.6 0.4 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EEB06415.1 - 0.035 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EEB06415.1 - 0.05 13.6 0.4 0.091 12.8 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EEB06415.1 - 0.065 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Gp_dh_N PF00044.19 EEB06415.1 - 0.11 12.4 1.5 1 9.3 0.3 2.5 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ThiF PF00899.16 EEB06415.1 - 0.11 12.3 3.6 4.4 7.1 1.9 2.4 1 1 0 2 2 2 0 ThiF family ACBP PF00887.14 EEB06416.2 - 9.5e-30 102.1 1.1 1.3e-29 101.7 0.8 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Sec34 PF04136.10 EEB06417.2 - 5.6e-27 94.3 2.3 5.6e-27 94.3 1.6 2.8 3 0 0 3 3 3 1 Sec34-like family DUF3772 PF12607.3 EEB06417.2 - 0.099 12.2 0.4 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) UPF0121 PF03661.8 EEB06418.1 - 5.7e-16 58.4 13.8 7.2e-16 58.1 9.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Lyase_1 PF00206.15 EEB06419.1 - 4.8e-101 338.0 0.0 8e-101 337.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EEB06419.1 - 2.5e-27 94.7 0.1 5.1e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal RED_N PF07808.8 EEB06420.1 - 5.9e-07 28.9 2.5 5.9e-07 28.9 1.8 3.6 3 1 1 4 4 4 1 RED-like protein N-terminal region SHOCT PF09851.4 EEB06420.1 - 0.016 14.6 0.1 0.016 14.6 0.1 3.0 3 0 0 3 3 3 0 Short C-terminal domain Ribonucleas_3_3 PF14622.1 EEB06421.2 - 5.8e-33 113.5 0.0 7.7e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEB06421.2 - 0.026 14.9 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain Beta-lactamase2 PF13354.1 EEB06421.2 - 0.035 13.5 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase enzyme family SID PF11778.3 EEB06422.1 - 3e-22 78.9 0.0 6.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Septation initiation PLU-1 PF08429.6 EEB06423.2 - 7.2e-63 212.5 19.4 1e-58 198.8 10.6 2.4 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EEB06423.2 - 1.4e-26 92.9 0.1 4.5e-26 91.3 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EEB06423.2 - 8.8e-18 63.7 56.3 2.3e-07 30.4 6.0 4.5 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 EEB06423.2 - 3.7e-09 36.5 3.1 3.7e-09 36.5 2.2 3.6 3 0 0 3 3 3 1 C5HC2 zinc finger bPH_4 PF06713.6 EEB06423.2 - 0.033 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial PH domain PHD_3 PF13922.1 EEB06423.2 - 0.2 11.8 8.1 0.13 12.5 0.9 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-Sec23_Sec24 PF04810.10 EEB06423.2 - 3.2 7.3 19.0 0.42 10.2 0.1 4.5 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger MTHFR PF02219.12 EEB06424.1 - 5.4e-107 357.1 0.1 7.1e-107 356.7 0.1 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SEP PF08059.8 EEB06425.1 - 3.7e-25 88.0 0.2 1e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EEB06425.1 - 1.9e-11 43.8 0.1 6e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 EEB06425.1 - 5.1e-07 29.1 0.1 9.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.8 EEB06425.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NPDC1 PF06809.6 EEB06425.1 - 0.011 14.6 0.4 0.011 14.6 0.3 2.0 2 1 1 3 3 3 0 Neural proliferation differentiation control-1 protein (NPDC1) GET2 PF08690.5 EEB06425.1 - 0.59 9.3 3.6 0.9 8.7 2.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Macoilin PF09726.4 EEB06425.1 - 1.5 6.9 9.5 2.3 6.3 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S6 PF01250.12 EEB06426.1 - 4.8e-05 23.1 0.0 7.1e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S6 RRM_1 PF00076.17 EEB06427.1 - 3.7e-31 106.5 2.4 3e-15 55.5 0.3 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06427.1 - 3.2e-24 84.6 0.1 3.4e-11 42.9 0.1 4.1 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06427.1 - 8.3e-15 54.3 1.1 3.5e-06 26.7 0.0 3.4 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB06427.1 - 0.0018 17.9 0.1 0.034 13.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EEB06427.1 - 0.0046 16.6 1.2 1.7 8.4 0.3 2.6 2 0 0 2 2 2 2 Limkain b1 Scramblase PF03803.10 EEB06428.2 - 2.7e-67 226.1 0.0 3.3e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Scramblase ATP-synt_ab PF00006.20 EEB06429.2 - 1.4e-111 371.1 0.0 2.5e-111 370.3 0.0 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 EEB06429.2 - 1.2e-73 247.3 0.0 1.7e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 EEB06429.2 - 5.8e-34 116.3 0.1 3.1e-28 97.9 0.0 2.7 3 0 0 3 3 3 2 Homing endonuclease ATP-synt_ab_C PF00306.22 EEB06429.2 - 3.5e-20 72.5 0.6 1e-19 71.0 0.1 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEB06429.2 - 1.3e-13 50.9 1.2 3e-13 49.7 0.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 EEB06429.2 - 1.9e-06 28.0 0.0 5.4e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 LAGLIDADG-like domain Hint PF01079.15 EEB06429.2 - 0.00029 20.1 0.0 0.00071 18.8 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 EEB06429.2 - 0.0024 17.8 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 Hint domain DUF1229 PF06797.6 EEB06429.2 - 0.27 10.0 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) WD40 PF00400.27 EEB06430.1 - 2.2e-43 144.6 12.0 6.7e-09 35.2 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEB06430.1 - 6e-05 22.0 0.2 0.29 9.9 0.0 2.9 3 0 0 3 3 3 2 Coatomer WD associated region Imm23 PF15593.1 EEB06430.1 - 0.051 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 23 zf-Apc11 PF12861.2 EEB06431.1 - 1.7e-44 149.5 8.6 1.9e-44 149.4 6.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEB06431.1 - 5.4e-31 106.5 9.8 6.1e-31 106.3 6.8 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEB06431.1 - 5.4e-06 26.1 16.3 5.5e-05 22.9 11.3 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB06431.1 - 2e-05 24.5 5.6 2e-05 24.5 3.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EEB06431.1 - 0.00031 20.1 3.7 0.00046 19.6 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EEB06431.1 - 0.0012 18.4 9.5 0.0058 16.2 3.7 2.4 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB06431.1 - 0.0047 16.5 13.3 0.022 14.4 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06431.1 - 0.0054 16.4 14.5 0.099 12.3 10.2 2.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EEB06431.1 - 0.0087 15.8 0.4 0.0087 15.8 0.3 2.2 1 1 1 2 2 2 1 zf-RING of BARD1-type protein FANCL_C PF11793.3 EEB06431.1 - 0.66 9.9 17.6 9.3 6.2 11.3 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EEB06431.1 - 0.78 9.8 10.1 0.22 11.5 3.7 2.2 2 1 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 EEB06431.1 - 3.8 7.1 12.2 7.3 6.2 3.9 2.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L19 PF01245.15 EEB06432.1 - 1.1e-17 63.8 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 GHMP_kinases_N PF00288.21 EEB06433.2 - 2.1e-12 46.9 0.4 4.4e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEB06433.2 - 2.7e-07 30.6 0.0 6.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Perilipin PF03036.11 EEB06433.2 - 0.015 14.1 0.6 0.029 13.2 0.1 1.6 2 0 0 2 2 2 0 Perilipin family GIY-YIG PF01541.19 EEB06434.1 - 4.6e-09 36.5 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 EEB06434.1 - 0.076 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain FANCL_C PF11793.3 EEB06434.1 - 0.079 12.9 8.0 0.15 12.0 4.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain TFIID-31kDa PF02291.10 EEB06435.1 - 5.7e-56 187.8 0.0 6.5e-56 187.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EEB06435.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S Bromo_TP PF07524.8 EEB06435.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated RTC PF01137.16 EEB06436.1 - 3e-61 206.1 0.0 3.7e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EEB06436.1 - 2.7e-32 110.8 0.0 4.3e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MarR_2 PF12802.2 EEB06436.1 - 0.11 12.1 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 MarR family API5 PF05918.6 EEB06437.1 - 0.015 13.8 3.2 0.027 12.9 2.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_L6 PF00347.18 EEB06438.1 - 5.9e-27 93.9 0.0 1.6e-15 57.3 0.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L6 DUF544 PF04424.8 EEB06441.1 - 1.2e-17 63.8 0.2 2.5e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) SET PF00856.23 EEB06442.1 - 6.9e-05 23.2 0.0 0.00036 20.8 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF3384 PF11864.3 EEB06442.1 - 0.012 14.0 0.1 0.017 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF972 PF06156.8 EEB06443.1 - 2.3 8.5 6.7 18 5.7 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ribonuc_P_40 PF08584.6 EEB06445.1 - 0.17 10.8 1.2 0.26 10.2 0.8 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit SUI1 PF01253.17 EEB06446.1 - 5.4e-20 70.9 1.4 1.8e-18 66.0 0.8 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 SLD3 PF08639.5 EEB06446.1 - 0.061 11.9 0.3 0.066 11.8 0.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 HK97-gp10_like PF04883.7 EEB06446.1 - 1.3 10.0 4.4 4.1 8.4 2.9 1.9 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component BNR PF02012.15 EEB06447.1 - 2.2e-08 32.6 28.7 6.7 6.9 0.0 11.1 11 0 0 11 11 11 7 BNR/Asp-box repeat BNR_2 PF13088.1 EEB06447.1 - 4.3e-06 26.2 0.3 7.7 5.7 0.0 6.0 2 2 4 6 6 6 3 BNR repeat-like domain PSII_BNR PF14870.1 EEB06447.1 - 3.7e-05 22.8 0.0 0.003 16.6 0.0 3.7 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 AAA PF00004.24 EEB06448.1 - 9.6e-40 135.8 0.0 1.7e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB06448.1 - 4.1e-06 26.9 0.0 0.0005 20.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEB06448.1 - 2.9e-05 23.8 0.1 0.00016 21.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEB06448.1 - 0.00024 21.0 0.0 0.00073 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEB06448.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEB06448.1 - 0.0017 19.2 0.1 0.0048 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEB06448.1 - 0.0028 16.6 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EEB06448.1 - 0.0046 16.6 0.1 0.013 15.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEB06448.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEB06448.1 - 0.0079 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEB06448.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEB06448.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEB06448.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EEB06448.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEB06448.1 - 0.031 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EEB06448.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEB06448.1 - 0.038 13.7 0.0 6.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 EEB06448.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EEB06448.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EEB06448.1 - 0.079 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EEB06448.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EEB06448.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus UCR_hinge PF02320.11 EEB06449.1 - 1.3e-20 73.0 6.6 3.3e-20 71.7 4.6 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Dicty_REP PF05086.7 EEB06449.1 - 0.068 10.9 8.3 0.087 10.5 5.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PMT PF02366.13 EEB06450.1 - 1.2e-83 280.2 22.8 1.2e-83 280.2 15.8 2.7 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEB06450.1 - 7e-14 51.7 0.5 1.5e-13 50.7 0.2 1.6 1 1 0 1 1 1 1 MIR domain adh_short PF00106.20 EEB06451.1 - 1.4e-31 109.7 0.0 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB06451.1 - 1.1e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB06451.1 - 8.2e-12 45.3 0.1 9.9e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEB06451.1 - 0.0012 17.7 0.4 0.0017 17.3 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2538 PF10804.3 EEB06451.1 - 0.12 12.2 0.1 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) DUF1776 PF08643.5 EEB06451.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EEB06451.1 - 0.12 12.1 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ctr PF04145.10 EEB06452.2 - 3.7e-22 78.9 14.1 2.7e-21 76.1 9.8 1.9 1 1 0 1 1 1 1 Ctr copper transporter family DUF485 PF04341.7 EEB06452.2 - 0.00072 19.2 5.7 0.26 10.9 1.4 2.6 2 1 1 3 3 3 2 Protein of unknown function, DUF485 DUF4184 PF13803.1 EEB06452.2 - 0.011 15.0 2.0 0.014 14.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Noc2 PF03715.8 EEB06453.1 - 2.4e-100 335.2 1.2 2.4e-100 335.2 0.9 2.0 2 0 0 2 2 2 1 Noc2p family AT_hook PF02178.14 EEB06454.1 - 3.9 7.4 38.8 0.067 12.8 3.5 4.6 4 0 0 4 4 4 0 AT hook motif TPR_11 PF13414.1 EEB06455.1 - 2.4e-28 97.5 11.5 4.6e-19 67.8 0.3 3.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEB06455.1 - 4.2e-26 89.4 1.4 3e-10 39.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEB06455.1 - 7.8e-21 72.2 7.4 1.6e-08 33.8 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06455.1 - 3.4e-14 51.4 1.8 5.1e-06 25.8 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB06455.1 - 1.7e-13 49.6 3.4 0.00057 19.8 0.0 4.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06455.1 - 2.2e-13 49.5 2.6 1.7e-05 25.0 0.0 4.3 2 2 3 5 5 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06455.1 - 8.8e-12 43.8 1.1 0.0024 17.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06455.1 - 4.7e-11 42.4 12.1 1.3e-10 41.0 1.1 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06455.1 - 6.6e-11 42.5 5.0 5.1e-07 30.1 1.2 2.9 2 2 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06455.1 - 3.9e-09 36.7 1.5 1.5e-05 25.2 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB06455.1 - 3.2e-08 33.2 0.8 8e-05 22.4 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB06455.1 - 1.4e-07 31.5 3.8 5.3e-07 29.6 0.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEB06455.1 - 1.5e-05 24.1 0.6 3.5e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.12 EEB06455.1 - 3e-05 24.3 0.3 3e-05 24.3 0.2 2.7 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 EEB06455.1 - 4.9e-05 23.5 1.1 0.27 11.7 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 EEB06455.1 - 0.0075 16.0 0.7 1.3 8.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Ferritin_2 PF13668.1 EEB06455.1 - 0.023 14.6 4.3 0.059 13.3 3.0 1.7 1 0 0 1 1 1 0 Ferritin-like domain TPR_10 PF13374.1 EEB06455.1 - 0.024 14.5 2.2 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EEB06455.1 - 0.064 13.1 14.7 0.62 9.9 1.0 3.5 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain DapB_C PF05173.9 EEB06455.1 - 0.074 12.8 0.5 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, C-terminus TPR_4 PF07721.9 EEB06455.1 - 0.075 13.5 0.0 9.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEB06455.1 - 2.9 7.8 7.3 12 5.8 0.3 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.9 EEB06456.1 - 1.1e-69 235.1 2.1 1.1e-69 235.1 1.5 1.8 2 0 0 2 2 2 1 Transcriptional repressor TCF25 zf-CCHC PF00098.18 EEB06457.2 - 4.2e-10 39.0 23.8 0.0005 19.8 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EEB06457.2 - 0.00017 21.1 28.1 0.071 12.7 0.9 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.1 EEB06457.2 - 0.0002 20.7 20.1 0.02 14.3 1.7 4.3 3 1 1 4 4 4 2 Zinc knuckle DEAD PF00270.24 EEB06458.1 - 1.3e-16 60.5 0.0 2.9e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB06458.1 - 3.3e-08 33.2 0.2 7.6e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB06458.1 - 3.3e-07 30.2 0.0 3.3e-07 30.2 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEB06458.1 - 0.039 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2201_N PF13203.1 EEB06458.1 - 0.7 9.0 15.4 1.2 8.2 0.2 2.5 2 0 0 2 2 2 0 Putative metallopeptidase domain SSP160 PF06933.6 EEB06458.1 - 8.4 4.2 6.0 15 3.3 4.0 1.4 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 CTP_transf_2 PF01467.21 EEB06459.1 - 0.016 15.3 0.0 0.057 13.4 0.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase Citrate_ly_lig PF08218.6 EEB06459.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Citrate lyase ligase C-terminal domain HIGH_NTase1 PF05636.6 EEB06459.1 - 0.044 12.8 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase UPF0160 PF03690.8 EEB06460.2 - 1.2e-118 396.2 0.0 1.3e-118 396.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF641 PF04859.7 EEB06461.1 - 0.0011 18.7 0.3 0.002 17.9 0.2 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Syntaphilin PF15290.1 EEB06461.1 - 0.034 13.6 2.0 0.06 12.8 0.4 1.9 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp MerR-DNA-bind PF09278.6 EEB06461.1 - 0.045 14.1 0.8 0.1 12.9 0.6 1.6 1 0 0 1 1 1 0 MerR, DNA binding Kinetocho_Slk19 PF12709.2 EEB06461.1 - 0.049 13.6 1.1 0.049 13.6 0.8 2.0 2 0 0 2 2 2 0 Central kinetochore-associated GrpE PF01025.14 EEB06461.1 - 0.15 11.5 2.6 0.16 11.5 0.3 1.9 2 0 0 2 2 2 0 GrpE ATP12 PF07542.6 EEB06462.1 - 6.4e-22 77.7 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF572 PF04502.8 EEB06463.1 - 1e-70 238.5 7.1 1.2e-70 238.3 4.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 EEB06463.1 - 0.042 13.4 1.9 0.23 11.1 0.6 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Lar_restr_allev PF14354.1 EEB06463.1 - 0.045 14.0 1.0 1.5 9.1 1.2 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-dskA_traR PF01258.12 EEB06463.1 - 0.11 12.2 0.7 0.99 9.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Caudo_TAP PF02413.12 EEB06463.1 - 0.19 11.8 7.2 0.4 10.8 4.8 1.8 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF3449 PF11931.3 EEB06463.1 - 0.46 9.9 7.4 0.71 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Grp1_Fun34_YaaH PF01184.14 EEB06464.1 - 5.6e-77 257.7 18.8 7.1e-77 257.4 13.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3681 PF12442.3 EEB06464.1 - 0.24 11.5 3.0 0.94 9.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) UPF0300 PF08594.5 EEB06465.1 - 7.9e-43 145.8 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Mannosyl_trans3 PF11051.3 EEB06465.1 - 0.073 12.4 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative zf-RING_2 PF13639.1 EEB06466.2 - 9.1e-13 47.8 9.4 1.5e-12 47.1 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB06466.2 - 1.3e-08 34.6 10.4 1.3e-08 34.6 7.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEB06466.2 - 9.5e-08 32.0 4.9 1.8e-07 31.1 3.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEB06466.2 - 5.7e-07 29.0 6.2 9.7e-07 28.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB06466.2 - 1.9e-06 27.4 8.2 3.3e-06 26.6 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 EEB06466.2 - 2.6e-06 27.0 0.0 5.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Prok-RING_1 PF14446.1 EEB06466.2 - 3.6e-06 26.5 4.2 3.6e-06 26.5 1.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EEB06466.2 - 5.8e-06 25.9 7.1 9.3e-06 25.2 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.24 EEB06466.2 - 0.0012 18.5 4.9 0.0021 17.7 3.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.1 EEB06466.2 - 0.019 14.6 3.2 0.4 10.4 2.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EEB06466.2 - 0.023 14.5 8.5 0.16 11.8 6.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EEB06466.2 - 0.08 12.9 7.1 0.54 10.2 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EEB06466.2 - 0.79 9.7 5.0 1.4 8.9 3.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EEB06466.2 - 1.2 8.8 6.4 2.4 7.8 4.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EEB06466.2 - 1.2 9.1 6.1 2.9 8.0 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EEB06466.2 - 2.4 8.0 9.1 6.4 6.7 6.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Adaptin_N PF01602.15 EEB06467.1 - 4.2e-115 385.0 1.1 5.8e-115 384.5 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EEB06467.1 - 3e-49 166.7 7.4 7.3e-49 165.4 5.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EEB06467.1 - 3.7e-15 55.9 1.4 5e-05 23.5 0.0 5.7 2 2 2 5 5 5 4 HEAT repeats RICTOR_N PF14664.1 EEB06467.1 - 9.1e-05 21.1 0.3 0.0002 20.0 0.2 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term HEAT PF02985.17 EEB06467.1 - 0.00055 19.7 0.0 12 6.2 0.1 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EEB06467.1 - 0.00077 19.3 5.5 0.031 14.1 0.2 3.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EEB06467.1 - 0.014 15.8 1.3 0.19 12.2 0.2 3.4 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.3 EEB06467.1 - 0.058 12.7 0.5 0.99 8.7 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Raptor_N PF14538.1 EEB06468.2 - 9.4e-67 223.6 0.0 1.9e-66 222.6 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EEB06468.2 - 3.9e-08 32.8 6.1 0.67 9.9 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EEB06468.2 - 1.1e-07 31.2 1.5 0.1 12.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 EEB06468.2 - 0.00046 20.0 0.0 0.31 10.8 0.0 2.7 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEB06468.2 - 0.005 17.0 0.0 0.055 13.7 0.0 2.5 1 1 0 1 1 1 1 HEAT repeats HSP70 PF00012.15 EEB06469.1 - 1.5e-66 224.6 3.5 1e-65 221.8 1.0 2.0 2 0 0 2 2 2 2 Hsp70 protein RRM_6 PF14259.1 EEB06470.2 - 0.00029 20.7 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EEB06470.2 - 0.016 15.0 1.8 0.016 15.0 1.3 1.8 2 0 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.17 EEB06470.2 - 0.016 14.8 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0128 PF03673.8 EEB06470.2 - 0.027 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) RRM_5 PF13893.1 EEB06470.2 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-ribbon_3 PF13248.1 EEB06470.2 - 1.1 8.5 9.5 0.13 11.5 3.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EEB06470.2 - 2.8 7.5 8.5 0.57 9.7 3.4 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.13 EEB06470.2 - 3.5 6.8 7.9 0.33 10.1 1.9 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF35_N PF12172.3 EEB06470.2 - 3.9 7.5 7.9 1.1 9.2 3.0 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_S8 PF00410.14 EEB06471.1 - 1e-26 93.2 0.1 1.4e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Neur_chan_memb PF02932.11 EEB06472.1 - 0.26 11.1 1.6 0.63 9.8 0.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.9 EEB06472.1 - 0.42 10.5 4.1 0.13 12.2 0.5 1.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) MADF_DNA_bdg PF10545.4 EEB06472.1 - 2.4 8.3 5.9 0.74 10.0 0.4 2.3 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Mem_trans PF03547.13 EEB06473.2 - 1.7e-64 217.5 1.3 2e-64 217.3 0.9 1.1 1 0 0 1 1 1 1 Membrane transport protein Chlor_dismutase PF06778.7 EEB06474.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Chlorite dismutase GPP34 PF05719.6 EEB06475.1 - 4.5e-64 216.2 0.0 5.9e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ECSIT PF06239.6 EEB06476.1 - 0.016 14.0 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway RF-1 PF00472.15 EEB06477.2 - 2.4e-34 117.5 5.3 2.4e-34 117.5 3.7 2.1 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EEB06477.2 - 9.3e-26 89.8 1.9 1.4e-25 89.2 0.0 2.3 2 0 0 2 2 2 1 PCRF domain PX PF00787.19 EEB06478.2 - 1.2e-17 63.6 1.2 3.1e-17 62.4 0.8 1.7 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 EEB06478.2 - 1.3e-15 56.6 2.4 2.4e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EEB06478.2 - 5.9e-09 35.7 0.1 2.1e-06 27.5 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain MRP-S28 PF10213.4 EEB06479.2 - 1.9e-21 76.4 0.0 3.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein ECR1_N PF14382.1 EEB06480.1 - 1.7e-16 59.1 0.0 3.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EEB06480.1 - 0.0019 18.1 0.0 0.04 13.8 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EEB06480.1 - 0.014 15.5 0.1 0.081 13.0 0.0 2.4 2 0 0 2 2 2 0 S1 RNA binding domain tRNA-synt_1b PF00579.20 EEB06481.1 - 2.9e-28 98.8 0.0 7.4e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TFIIB PF00382.14 EEB06482.1 - 1.8e-44 149.4 0.4 7e-25 86.6 0.5 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEB06482.1 - 1.2e-12 46.9 1.8 1.9e-12 46.2 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EEB06482.1 - 0.015 14.8 0.1 0.064 12.8 0.1 2.0 3 0 0 3 3 3 0 Cyclin, N-terminal domain HTH_23 PF13384.1 EEB06482.1 - 0.049 13.2 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EEB06482.1 - 0.057 12.8 0.3 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_5 PF01022.15 EEB06482.1 - 0.079 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.1 EEB06482.1 - 0.12 11.5 0.0 16 4.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MerR PF00376.18 EEB06482.1 - 0.15 11.6 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein CoA_binding PF02629.14 EEB06483.1 - 1.4e-26 92.8 3.0 6.3e-26 90.7 0.7 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EEB06483.1 - 1.6e-24 86.2 0.0 3.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEB06483.1 - 3.9e-06 26.5 0.0 7.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEB06483.1 - 3.9e-06 27.0 0.0 2.5e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EEB06483.1 - 0.0016 18.9 0.2 0.0037 17.7 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RVP_2 PF08284.6 EEB06484.2 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease TBCC PF07986.7 EEB06485.1 - 8.3e-08 31.6 0.8 1.8e-07 30.5 0.6 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C FlgN PF05130.7 EEB06485.1 - 1.5 9.1 6.6 4.5 7.5 0.8 2.3 2 0 0 2 2 2 0 FlgN protein DUF2370 PF10176.4 EEB06486.2 - 2.8e-39 134.8 8.3 5.2e-39 133.9 0.1 2.7 1 1 2 3 3 3 2 Protein of unknown function (DUF2370) TMEM51 PF15345.1 EEB06486.2 - 0.033 13.8 0.4 0.95 9.1 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 UCH PF00443.24 EEB06487.1 - 8.3e-51 172.6 1.4 1.9e-50 171.4 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EEB06487.1 - 3.2e-50 167.3 2.6 4.5e-19 67.6 0.1 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EEB06487.1 - 2.2e-16 60.1 4.4 6.9e-07 28.9 0.0 3.4 2 1 1 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase End_N_terminal PF12218.3 EEB06487.1 - 0.033 13.6 0.8 0.11 12.0 0.0 2.2 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase AIF-MLS PF14962.1 EEB06487.1 - 0.44 10.1 1.6 0.95 9.0 1.1 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence RRM_1 PF00076.17 EEB06488.2 - 5.2e-54 179.7 0.0 9.6e-18 63.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06488.2 - 1.7e-44 149.6 0.0 5.8e-15 55.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06488.2 - 1e-24 86.1 0.0 4.8e-09 35.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEB06488.2 - 0.0002 21.0 0.1 0.019 14.6 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 AAA PF00004.24 EEB06489.1 - 1.5e-38 132.0 0.0 2.4e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB06489.1 - 3.2e-06 27.3 0.2 0.00011 22.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 EEB06489.1 - 1.2e-05 25.1 0.0 4e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EEB06489.1 - 2.3e-05 23.5 0.0 4.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEB06489.1 - 0.00032 20.7 0.6 0.0052 16.7 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEB06489.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EEB06489.1 - 0.00069 18.4 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EEB06489.1 - 0.0015 17.9 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EEB06489.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EEB06489.1 - 0.0021 17.7 0.1 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EEB06489.1 - 0.0032 16.6 0.1 0.007 15.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EEB06489.1 - 0.0041 17.0 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEB06489.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEB06489.1 - 0.0048 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEB06489.1 - 0.0054 16.3 0.2 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEB06489.1 - 0.007 15.7 0.1 0.086 12.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EEB06489.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEB06489.1 - 0.028 15.2 0.0 0.092 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB06489.1 - 0.05 13.9 0.0 0.24 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEB06489.1 - 0.06 13.0 0.0 0.52 9.9 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EEB06489.1 - 0.068 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 EEB06489.1 - 0.079 12.3 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase PhoH PF02562.11 EEB06489.1 - 0.088 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EEB06489.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EEB06489.1 - 0.16 11.0 0.1 1.6 7.7 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 EEB06489.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.2 3 0 0 3 3 2 0 AAA domain Glyco_transf_20 PF00982.16 EEB06490.2 - 3e-202 672.3 0.0 3.4e-202 672.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEB06490.2 - 0.04 13.4 0.1 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB06490.2 - 0.13 11.6 0.1 2.8 7.3 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferases group 1 HSF_DNA-bind PF00447.12 EEB06491.2 - 1.7e-35 121.3 0.8 3.5e-35 120.3 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1759 PF03564.10 EEB06491.2 - 0.00093 19.0 0.2 0.0021 17.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) IBR PF01485.16 EEB06492.2 - 3.6e-20 71.6 48.0 7.5e-12 44.9 5.0 4.9 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EEB06492.2 - 3.1e-05 23.5 4.1 3.1e-05 23.5 2.8 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB06492.2 - 0.00051 20.0 6.0 0.00051 20.0 4.1 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB06492.2 - 0.012 15.4 6.5 0.012 15.4 4.5 4.0 4 0 0 4 4 4 0 Ring finger domain DUF1488 PF07369.6 EEB06492.2 - 0.16 11.7 3.5 6 6.7 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1488) Xpo1 PF08389.7 EEB06493.1 - 3e-13 49.9 1.8 3e-13 49.9 1.2 3.4 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EEB06493.1 - 0.0026 17.6 0.1 0.013 15.3 0.1 2.3 1 1 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.18 EEB06493.1 - 0.015 15.1 0.1 0.015 15.1 0.0 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-CCCH PF00642.19 EEB06494.1 - 8.5e-09 34.9 8.2 0.00067 19.2 1.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) eIF_4EBP PF05456.6 EEB06494.1 - 0.008 15.8 4.0 0.025 14.2 0.2 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRV_FeS PF05484.6 EEB06494.1 - 1.5 8.4 3.3 6.5 6.4 0.2 2.3 1 1 1 2 2 2 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 EEB06494.1 - 2 8.5 16.7 4.7 7.3 3.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Methyltransf_16 PF10294.4 EEB06495.2 - 5.6e-21 74.7 0.1 7.9e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EEB06495.2 - 7.5e-07 28.5 0.1 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EEB06495.2 - 5.3e-06 26.9 0.1 8.4e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB06495.2 - 8.4e-06 25.2 0.1 1.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EEB06495.2 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 EEB06495.2 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEB06495.2 - 0.0025 17.8 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB06495.2 - 0.024 15.1 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain UcrQ PF02939.11 EEB06495.2 - 0.046 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 UcrQ family Seipin PF06775.9 EEB06496.2 - 1.2e-31 109.7 3.6 1.6e-31 109.3 2.5 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) EF-hand_8 PF13833.1 EEB06497.1 - 0.004 16.7 0.1 0.11 12.1 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEB06497.1 - 0.12 12.2 0.6 0.82 9.7 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EEB06497.1 - 0.15 11.4 2.7 0.55 9.6 0.6 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EEB06497.1 - 0.43 10.7 2.9 2.3 8.4 0.2 3.2 3 0 0 3 3 3 0 EF-hand domain pair Tropomyosin PF00261.15 EEB06497.1 - 0.47 9.5 40.5 0.01 14.9 15.8 3.2 3 0 0 3 3 3 0 Tropomyosin Pyr_redox_2 PF07992.9 EEB06498.1 - 1.1e-27 97.1 0.0 5e-27 95.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB06498.1 - 1.2e-10 41.6 0.0 3e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB06498.1 - 3.6e-07 30.4 0.2 0.01 15.9 0.1 3.9 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase MPC PF03650.8 EEB06498.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0041) Cullin PF00888.17 EEB06499.1 - 2.4e-122 409.4 7.9 3.4e-122 408.9 5.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEB06499.1 - 5.3e-23 80.6 1.1 2.5e-22 78.4 0.7 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain Na_H_Exchanger PF00999.16 EEB06500.2 - 9.6e-73 244.8 27.6 1.1e-72 244.6 19.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EEB06500.2 - 0.0022 17.3 9.7 0.0022 17.3 6.7 2.3 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.1 EEB06500.2 - 0.033 13.7 0.3 0.033 13.7 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) LVIVD PF08309.6 EEB06500.2 - 0.52 9.3 2.1 19 4.3 0.0 2.5 2 0 0 2 2 2 0 LVIVD repeat Peptidase_M19 PF01244.16 EEB06501.1 - 2.5e-103 345.3 0.0 3e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Aldo_ket_red PF00248.16 EEB06502.1 - 3.5e-63 213.0 0.0 4.1e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 EEB06503.1 - 2.5e-41 140.9 0.2 7.7e-41 139.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEB06503.1 - 2.8e-05 24.0 0.0 8.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEB06503.1 - 4.2e-05 23.2 1.5 0.00014 21.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEB06503.1 - 4.3e-05 23.5 1.9 0.0073 16.3 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEB06503.1 - 0.00038 20.6 1.4 0.01 15.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEB06503.1 - 0.0006 18.9 0.0 0.0016 17.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEB06503.1 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EEB06503.1 - 0.01 15.1 0.1 0.035 13.3 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.1 EEB06503.1 - 0.011 15.3 1.0 0.48 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EEB06503.1 - 0.013 14.6 0.1 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEB06503.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EEB06503.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 EEB06503.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ribosomal_S19 PF00203.16 EEB06503.1 - 0.023 14.2 0.2 6.3 6.5 0.0 3.3 3 1 0 3 3 3 0 Ribosomal protein S19 AAA_14 PF13173.1 EEB06503.1 - 0.031 14.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EEB06503.1 - 0.041 14.6 0.2 0.17 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEB06503.1 - 0.054 12.8 1.3 0.51 9.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EEB06503.1 - 0.057 13.0 0.1 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB06503.1 - 0.1 12.9 1.1 5.4 7.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain GrpE PF01025.14 EEB06503.1 - 0.73 9.3 10.1 0.38 10.2 4.8 2.0 2 0 0 2 2 2 0 GrpE TMF_TATA_bd PF12325.3 EEB06503.1 - 2.3 7.9 12.0 1 9.0 5.1 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 EEB06504.1 - 2.7e-22 78.5 9.1 3e-22 78.3 6.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Spore_YpjB PF09577.5 EEB06504.1 - 0.016 14.8 2.2 0.018 14.6 1.5 1.0 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF1192 PF06698.6 EEB06504.1 - 0.052 13.3 1.7 6.3 6.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Prefoldin PF02996.12 EEB06504.1 - 0.061 12.9 7.2 0.13 11.9 1.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit FTA4 PF13093.1 EEB06504.1 - 0.073 12.4 3.9 0.09 12.2 2.7 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fib_alpha PF08702.5 EEB06504.1 - 0.077 13.1 6.7 0.51 10.4 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 EEB06504.1 - 0.11 13.1 3.0 0.13 12.9 1.5 1.6 1 1 1 2 2 2 0 Occludin homology domain DUF2046 PF09755.4 EEB06504.1 - 0.15 10.9 6.2 0.09 11.6 0.3 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) ERp29 PF07749.7 EEB06504.1 - 0.17 12.5 2.4 1.8 9.2 1.6 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain COG2 PF06148.6 EEB06504.1 - 0.28 11.0 6.2 2.2 8.1 0.3 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PEP-utilisers_N PF05524.8 EEB06504.1 - 0.29 10.9 3.7 8 6.2 0.2 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4404 PF14357.1 EEB06504.1 - 0.32 11.4 2.8 5.8 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1598 PF07643.6 EEB06504.1 - 0.37 10.8 2.3 0.86 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) Bacillus_HBL PF05791.6 EEB06504.1 - 0.39 10.0 6.3 4 6.7 0.6 2.1 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 EEB06504.1 - 0.55 10.0 6.2 1.4 8.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EEB06504.1 - 0.99 9.2 7.0 0.097 12.4 0.8 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.8 EEB06504.1 - 1.7 8.9 7.2 5.3 7.3 0.7 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 EEB06504.1 - 3.4 7.4 7.8 5.7 6.6 2.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 EEB06504.1 - 5.8 6.6 7.9 4.6 6.9 2.5 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EEB06504.1 - 7.6 6.0 10.4 1.4e+02 1.9 7.2 2.0 1 1 0 1 1 1 0 IncA protein Kinesin PF00225.18 EEB06505.1 - 4.8e-102 341.0 0.8 4.8e-102 341.0 0.6 2.2 2 1 0 2 2 2 1 Kinesin motor domain Myosin_tail_1 PF01576.14 EEB06505.1 - 1.7 6.2 51.6 0.066 10.9 12.7 3.0 2 1 1 3 3 3 0 Myosin tail KxDL PF10241.4 EEB06505.1 - 2.1 8.2 17.7 0.74 9.7 0.6 4.5 3 1 2 5 5 5 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.2 EEB06505.1 - 3.4 7.5 44.7 0.24 11.2 3.1 3.4 3 1 0 3 3 3 0 Tropomyosin like AAR2 PF05282.6 EEB06506.1 - 3.1e-31 108.6 3.8 8.2e-20 71.0 3.0 2.1 2 0 0 2 2 2 2 AAR2 protein Ribosomal_S11 PF00411.14 EEB06507.1 - 1.8e-41 140.7 1.0 2.1e-41 140.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 EEB06507.1 - 0.068 13.0 0.1 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DNA_pol_B PF00136.16 EEB06508.2 - 1.2e-115 387.0 1.3 2e-115 386.2 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEB06508.2 - 1.7e-33 115.8 0.2 3.5e-33 114.8 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EEB06508.2 - 4.8e-33 114.0 7.5 3.7e-32 111.2 2.0 2.7 3 0 0 3 3 3 2 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 EEB06508.2 - 2.6e-24 84.7 5.7 9.7e-24 82.9 3.9 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CAP_assoc_N PF14504.1 EEB06508.2 - 0.018 14.7 0.2 0.088 12.5 0.1 2.1 2 0 0 2 2 2 0 CAP-associated N-terminal Ribosomal_L30_N PF08079.7 EEB06509.1 - 1.4e-23 82.6 16.0 2.8e-23 81.7 11.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EEB06509.1 - 6.6e-20 70.4 1.4 9.5e-20 69.9 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF4594 PF15266.1 EEB06509.1 - 0.015 15.4 4.5 0.024 14.7 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) Gastrin PF00918.12 EEB06509.1 - 0.24 12.2 1.7 0.41 11.4 1.2 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family zf-C2H2_4 PF13894.1 EEB06511.1 - 0.13 12.6 0.4 0.42 11.0 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEB06511.1 - 0.15 12.5 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fes1 PF08609.5 EEB06513.1 - 7.3e-24 84.0 4.1 2.3e-23 82.4 1.5 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EEB06513.1 - 2.4e-05 24.5 0.4 0.0001 22.5 0.0 2.3 2 2 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EEB06513.1 - 0.00085 19.7 1.7 0.053 14.0 0.1 3.2 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 EEB06513.1 - 0.016 15.0 0.3 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pedibin PF08182.6 EEB06513.1 - 0.093 12.2 1.0 13 5.3 0.1 2.9 2 0 0 2 2 2 0 Pedibin/Hym-346 family G-patch_2 PF12656.2 EEB06514.1 - 1.2e-20 73.0 0.2 1.2e-20 73.0 0.2 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site RAB3GAP2_N PF14655.1 EEB06514.1 - 0.0055 15.7 3.1 0.0085 15.1 2.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CytadhesinP1 PF12378.3 EEB06514.1 - 0.082 12.8 2.3 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein SRP54 PF00448.17 EEB06515.2 - 2.6e-39 134.7 0.8 4.8e-39 133.8 0.2 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EEB06515.2 - 1.9e-11 43.9 6.4 3.4e-11 43.0 4.5 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EEB06515.2 - 0.0028 17.7 0.1 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArsA_ATPase PF02374.10 EEB06515.2 - 0.041 12.9 0.5 2 7.3 0.0 2.5 2 0 0 2 2 2 0 Anion-transporting ATPase Drc1-Sld2 PF11719.3 EEB06515.2 - 0.043 12.8 6.3 0.056 12.5 4.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein zf-CHY PF05495.7 EEB06517.1 - 2.3e-14 53.2 15.9 3.1e-14 52.8 11.0 1.2 1 0 0 1 1 1 1 CHY zinc finger DUF2296 PF10058.4 EEB06517.1 - 0.044 13.5 1.1 0.044 13.5 0.8 2.0 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_3 PF14369.1 EEB06517.1 - 0.096 12.7 6.3 0.17 11.9 0.1 2.8 2 1 1 3 3 3 0 zinc-finger zinc_ribbon_2 PF13240.1 EEB06517.1 - 0.18 11.3 6.5 0.47 10.0 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Trm112p PF03966.11 EEB06517.1 - 0.19 12.0 2.4 5.1 7.5 0.2 2.6 2 1 0 2 2 2 0 Trm112p-like protein zf-RING_4 PF14570.1 EEB06517.1 - 0.23 11.0 7.9 4 7.0 2.4 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EEB06517.1 - 0.35 10.7 7.7 1.9 8.3 5.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EEB06517.1 - 0.82 9.5 7.4 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.14 EEB06517.1 - 1.6 8.4 7.3 6.9 6.4 5.1 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF3797 PF12677.2 EEB06517.1 - 1.7 8.2 5.7 6.2 6.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3797) C1_4 PF07975.7 EEB06517.1 - 2.4 8.2 10.2 0.23 11.5 1.3 2.3 1 1 2 3 3 3 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 EEB06517.1 - 4.1 6.7 6.7 6 6.2 3.0 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Autophagy_N PF03986.8 EEB06518.1 - 1.4e-34 118.9 2.7 1.8e-34 118.5 1.9 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EEB06518.1 - 1e-24 86.4 0.4 2.5e-24 85.1 0.2 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EEB06518.1 - 2.5e-11 42.4 4.0 5.5e-11 41.3 2.8 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF2382 PF09557.5 EEB06518.1 - 0.024 14.5 1.2 0.052 13.4 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2382) SHS2_Rpb7-N PF03876.12 EEB06519.1 - 1.4e-09 37.9 0.0 3.4e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 WD40 PF00400.27 EEB06520.1 - 2.6e-31 106.3 16.6 2e-08 33.7 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEB06520.1 - 0.00066 19.4 0.4 2.6 7.8 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Elf1 PF05129.8 EEB06520.1 - 0.19 11.4 2.8 0.54 9.9 1.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Apt1 PF10351.4 EEB06521.1 - 1.6e-115 386.5 4.3 1.6e-115 386.5 3.0 2.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EEB06521.1 - 7.3e-111 370.8 14.6 7.3e-111 370.8 10.1 2.3 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EEB06521.1 - 1.6e-44 151.6 0.0 4.1e-44 150.2 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.4 EEB06521.1 - 7.1e-32 110.0 22.3 7.1e-32 110.0 15.5 3.4 4 0 0 4 4 4 2 Mitochondrial protein from FMP27 DUF2405 PF10293.4 EEB06521.1 - 4.1e-31 107.8 2.7 8.4e-31 106.8 0.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EEB06521.1 - 2e-24 85.9 0.6 9.3e-24 83.8 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L32e PF01655.13 EEB06522.1 - 7.9e-48 161.0 1.4 9.3e-48 160.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 NAD_kinase PF01513.16 EEB06523.1 - 8.2e-66 221.6 0.0 1e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF4598 PF15370.1 EEB06524.1 - 7.6e-10 39.0 4.8 1.3e-09 38.3 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Isy1 PF06246.7 EEB06524.1 - 0.039 13.3 4.0 0.043 13.2 2.8 1.1 1 0 0 1 1 1 0 Isy1-like splicing family DRY_EERY PF09750.4 EEB06524.1 - 0.66 10.0 4.2 1 9.4 2.6 1.7 1 1 0 1 1 1 0 Alternative splicing regulator Ribosomal_L18_c PF14204.1 EEB06525.2 - 1.3e-50 169.9 13.2 2.4e-31 108.1 3.4 2.5 2 0 0 2 2 2 2 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.17 EEB06525.2 - 4.1e-46 156.0 5.5 4.2e-16 59.2 0.0 4.1 5 1 1 6 6 6 3 Ribosomal L18p/L5e family Thr_synth_N PF14821.1 EEB06525.2 - 2.9e-05 23.9 1.4 0.56 10.2 0.2 3.5 2 2 0 2 2 2 2 Threonine synthase N terminus K_oxygenase PF13434.1 EEB06525.2 - 0.011 14.7 1.2 0.68 8.7 0.3 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1727 PF08353.5 EEB06525.2 - 0.061 12.9 0.3 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) DUF3642 PF12182.3 EEB06525.2 - 0.17 12.3 1.3 25 5.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial lipoprotein DUF2034 PF10356.4 EEB06526.1 - 1.1e-26 93.0 0.0 1.5e-13 50.3 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EEB06526.1 - 5.7e-10 39.0 0.0 8.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease PGAP1 PF07819.8 EEB06527.2 - 1.2e-78 263.7 0.0 1.8e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEB06527.2 - 1.3e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB06527.2 - 0.00071 19.5 0.1 0.0013 18.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB06527.2 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EEB06527.2 - 0.014 14.8 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EEB06527.2 - 0.19 11.9 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain PI3_PI4_kinase PF00454.22 EEB06528.2 - 1.9e-41 142.0 0.2 2.8e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-C3HC4_2 PF13923.1 EEB06529.1 - 9.6e-07 28.7 7.4 1.5e-06 28.0 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06529.1 - 3.1e-06 26.8 6.4 5e-06 26.1 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEB06529.1 - 4.9e-05 23.0 5.8 7.9e-05 22.4 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB06529.1 - 0.00015 21.3 7.0 0.00031 20.3 4.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB06529.1 - 0.00066 19.2 6.4 0.0012 18.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEB06529.1 - 0.0032 17.1 9.7 0.015 15.0 6.7 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EEB06529.1 - 0.0055 16.3 1.9 0.0097 15.6 0.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 EEB06529.1 - 0.0068 15.6 0.6 0.012 14.8 0.4 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-UDP PF14569.1 EEB06529.1 - 0.011 15.4 2.8 0.022 14.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.2 EEB06529.1 - 0.041 13.6 5.8 2.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 EEB06529.1 - 0.071 12.6 6.7 0.98 8.9 2.8 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EEB06529.1 - 0.077 12.2 6.7 1.5 8.0 3.1 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 EEB06529.1 - 0.088 12.4 4.9 0.15 11.6 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EEB06529.1 - 0.12 12.2 5.7 0.13 12.1 2.9 1.9 1 1 1 2 2 2 0 IBR domain zinc-ribbons_6 PF07191.7 EEB06529.1 - 0.45 10.3 4.8 1.3 8.9 3.3 1.7 1 1 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.1 EEB06529.1 - 1.3 8.9 7.0 5.3 6.9 4.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF329 PF03884.9 EEB06529.1 - 1.6 8.3 5.6 19 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 EEB06529.1 - 2.5 7.7 8.2 37 3.9 0.0 3.5 2 1 1 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EEB06529.1 - 8.3 6.7 7.9 26 5.2 5.2 2.1 2 1 0 2 2 1 0 Restriction alleviation protein Lar WD40 PF00400.27 EEB06530.2 - 2.4e-20 71.6 16.7 2.2e-05 24.1 0.5 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Aconitase PF00330.15 EEB06531.1 - 1.3e-73 248.1 0.0 6.7e-45 153.4 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEB06531.1 - 4e-25 88.4 0.0 8e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.12 EEB06532.2 - 2.4e-66 223.3 0.1 4.5e-66 222.4 0.1 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 EEB06532.2 - 2.4e-05 23.6 0.0 7.2e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EEB06532.2 - 9.7e-05 23.1 1.4 0.00041 21.1 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEB06532.2 - 0.0058 16.5 0.1 1.6 8.6 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EEB06532.2 - 0.057 13.7 0.5 0.81 9.9 0.3 2.7 1 1 0 1 1 1 0 AAA domain IF-2B PF01008.12 EEB06533.1 - 4.6e-67 225.9 0.1 6.3e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fucose_iso_N1 PF07881.7 EEB06533.1 - 0.078 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain GatB_N PF02934.10 EEB06534.1 - 9.6e-95 316.7 0.0 1.2e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EEB06534.1 - 5.9e-21 74.7 0.1 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 GatB domain Ferritin_2 PF13668.1 EEB06535.1 - 3.9e-19 68.9 0.3 6.2e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain Chromo PF00385.19 EEB06536.1 - 2.8e-10 39.7 1.2 2.8e-10 39.7 0.9 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EEB06536.1 - 2.4e-07 30.4 0.1 6.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain SR-25 PF10500.4 EEB06536.1 - 0.57 9.6 40.3 1.1 8.7 12.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L32e PF01655.13 EEB06537.2 - 4.4e-33 113.6 0.1 6e-33 113.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Las1 PF04031.8 EEB06538.1 - 8.8e-43 145.6 0.0 2.6e-42 144.0 0.0 1.9 1 0 0 1 1 1 1 Las1-like NAD_kinase PF01513.16 EEB06539.1 - 5.3e-78 261.6 0.0 6.7e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase zf-C2H2 PF00096.21 EEB06540.1 - 0.0012 19.0 0.6 0.0012 19.0 0.4 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEB06540.1 - 0.0074 16.1 0.6 0.0074 16.1 0.4 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-RanBP PF00641.13 EEB06541.1 - 2.6e-07 29.6 4.1 4.9e-07 28.7 2.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LSM PF01423.17 EEB06542.1 - 6.6e-18 64.0 0.1 8.1e-18 63.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain UBX PF00789.15 EEB06543.1 - 5.4e-12 45.6 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EEB06543.1 - 6.1e-06 25.6 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EEB06543.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain SPRY PF00622.23 EEB06544.1 - 2.8e-14 53.2 0.1 6.3e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 SPRY domain Response_reg PF00072.19 EEB06545.2 - 1.1e-19 70.4 0.2 6.8e-19 67.9 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEB06545.2 - 1.5e-18 66.5 0.1 3.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EEB06545.2 - 4e-12 46.5 0.1 2.3e-11 44.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 EEB06545.2 - 7.7e-11 42.6 0.0 2.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 EEB06545.2 - 6.2e-07 28.8 0.0 2.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EEB06545.2 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EEB06545.2 - 2.9e-05 23.2 0.0 7.3e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_3 PF08447.6 EEB06545.2 - 4.5e-05 23.4 0.0 0.00017 21.6 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.21 EEB06545.2 - 0.00035 20.2 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EEB06545.2 - 0.005 16.9 0.0 0.78 9.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EEB06545.2 - 0.068 13.6 0.0 0.55 10.7 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein Ribosomal_L27e PF01777.13 EEB06546.1 - 1.3e-38 131.0 2.0 1.7e-38 130.6 1.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEB06546.1 - 0.00029 20.4 0.6 0.00076 19.1 0.5 1.8 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.22 EEB06547.1 - 3.4e-34 116.4 9.3 1.2e-11 44.1 0.2 4.3 1 1 2 3 3 3 3 Mitochondrial carrier protein Oxysterol_BP PF01237.13 EEB06548.2 - 3e-85 285.8 0.2 3.6e-85 285.5 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L17 PF01196.14 EEB06549.1 - 8.6e-32 109.5 0.0 2e-31 108.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 ArgJ PF01960.13 EEB06550.1 - 1.6e-150 500.8 1.6 1.8e-150 500.6 1.1 1.0 1 0 0 1 1 1 1 ArgJ family zf-RING_2 PF13639.1 EEB06551.1 - 5e-16 58.2 5.2 5e-16 58.2 3.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB06551.1 - 2.5e-10 39.8 8.2 9.9e-09 34.7 1.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB06551.1 - 7.2e-08 32.3 5.3 7.2e-08 32.3 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06551.1 - 1.2e-07 31.2 11.1 7.2e-07 28.8 2.8 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.2 EEB06551.1 - 4.8e-07 29.7 2.1 4.8e-07 29.7 1.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEB06551.1 - 5e-06 26.0 4.1 5e-06 26.0 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EEB06551.1 - 2e-05 24.4 2.6 6.3e-05 22.8 1.8 1.9 1 0 0 1 1 1 1 zinc-finger DUF3279 PF11682.3 EEB06551.1 - 0.0028 17.2 1.0 0.0028 17.2 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3279) zf-Apc11 PF12861.2 EEB06551.1 - 0.0034 17.1 0.8 0.0034 17.1 0.6 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EEB06551.1 - 0.0054 16.4 5.5 0.0054 16.4 3.8 2.8 2 2 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EEB06551.1 - 0.0057 16.3 1.7 0.017 14.8 1.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 EEB06551.1 - 0.09 12.8 4.6 0.21 11.6 3.2 1.7 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 EEB06551.1 - 0.11 12.2 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Vps39_2 PF10367.4 EEB06551.1 - 0.12 12.5 1.3 0.22 11.7 0.2 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF1272 PF06906.6 EEB06551.1 - 0.57 10.0 4.7 2.6 7.9 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 EEB06551.1 - 1.5 8.1 9.3 0.05 12.8 1.8 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EEB06551.1 - 1.7 8.5 8.3 0.19 11.5 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbons FANCL_C PF11793.3 EEB06551.1 - 2.8 7.9 8.5 0.67 9.9 3.0 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain DZR PF12773.2 EEB06551.1 - 2.9 7.7 9.4 1.4 8.7 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon Fis1_TPR_C PF14853.1 EEB06552.1 - 9.8e-10 38.1 0.1 1.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EEB06552.1 - 0.00017 21.8 0.0 0.00041 20.6 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB06552.1 - 0.00059 19.5 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06552.1 - 0.0014 19.1 0.0 0.0051 17.3 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06552.1 - 0.0048 17.5 0.2 0.056 14.1 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEB06552.1 - 0.051 13.2 0.2 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 EEB06552.1 - 0.074 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEB06552.1 - 0.11 12.3 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat GDA1_CD39 PF01150.12 EEB06553.1 - 1.5e-101 340.0 0.0 1.9e-101 339.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Integrin_B_tail PF07965.7 EEB06553.1 - 0.25 11.8 2.1 0.55 10.7 0.2 2.1 2 0 0 2 2 2 0 Integrin beta tail domain Lactamase_B PF00753.22 EEB06554.1 - 3.9e-30 104.9 2.0 5.2e-30 104.5 1.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEB06554.1 - 2.1e-09 37.2 0.3 2.9e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEB06554.1 - 0.004 16.8 1.2 0.0083 15.8 0.8 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EEB06554.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DnaJ PF00226.26 EEB06555.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EEB06555.1 - 2.4e-05 24.1 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Pam16 Vps16_N PF04841.8 EEB06556.2 - 5.3e-92 308.4 0.0 8.2e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EEB06556.2 - 7.2e-91 304.4 9.3 1.1e-90 303.8 6.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region RIP PF00161.14 EEB06556.2 - 0.027 13.6 0.1 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosome inactivating protein DUF4082 PF13313.1 EEB06556.2 - 0.036 13.5 0.8 0.26 10.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) WD40 PF00400.27 EEB06557.1 - 2.1e-14 52.7 7.4 7.2e-07 28.8 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat bPH_5 PF10882.3 EEB06557.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain ArfGap PF01412.13 EEB06558.2 - 3e-41 139.8 1.4 5e-41 139.1 0.9 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Chromo_shadow PF01393.14 EEB06559.2 - 1.2e-25 89.0 0.1 7.3e-25 86.5 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EEB06559.2 - 2.3e-12 46.3 2.9 2.3e-12 46.3 2.0 2.7 3 1 1 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4463 PF14703.1 EEB06559.2 - 4.3 7.9 12.6 2.1 8.9 0.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) CDC27 PF09507.5 EEB06559.2 - 7.4 5.6 52.7 4.8 6.3 24.3 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF3295 PF11702.3 EEB06560.2 - 2.9e-16 59.5 23.5 2.9e-16 59.5 16.3 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EEB06560.2 - 7.9e-07 28.5 0.2 1.7e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TRAUB PF08164.7 EEB06561.1 - 4e-30 103.7 0.5 4e-30 103.7 0.3 3.0 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EEB06561.1 - 1.4e-19 70.5 2.6 1.4e-19 70.5 1.8 3.4 3 1 1 4 4 4 1 Apoptosis antagonizing transcription factor PROCT PF08084.6 EEB06561.1 - 0.081 12.6 0.1 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 PROCT (NUC072) domain Rad9 PF04139.8 EEB06562.2 - 1.1e-66 224.5 0.6 1.3e-66 224.2 0.4 1.1 1 0 0 1 1 1 1 Rad9 Ribosomal_L30 PF00327.15 EEB06563.2 - 2.2e-12 46.3 2.0 5.2e-12 45.1 0.2 2.6 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EEB06563.2 - 1.4e-06 28.1 15.3 1.4e-06 28.1 10.6 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L13e PF01294.13 EEB06565.1 - 3.1e-72 241.8 3.8 3.9e-72 241.4 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sod_Fe_N PF00081.17 EEB06565.1 - 0.035 14.3 0.0 0.087 13.0 0.0 1.7 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribosomal_S9 PF00380.14 EEB06566.1 - 2.5e-38 131.0 1.1 2.9e-38 130.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EEB06566.1 - 0.035 11.6 0.0 0.038 11.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Exo70 PF03081.10 EEB06566.1 - 0.17 10.6 0.4 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Paf1 PF03985.8 EEB06567.1 - 2.5e-83 280.2 0.0 3.2e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Paf1 Actin PF00022.14 EEB06568.1 - 3.5e-31 108.0 0.0 2.5e-22 78.8 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEB06568.1 - 0.0016 17.1 0.0 0.14 10.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein G_glu_transpept PF01019.16 EEB06569.1 - 2.2e-169 564.2 0.0 2.6e-169 564.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Kinesin PF00225.18 EEB06570.2 - 2.5e-105 351.8 0.8 2.5e-105 351.8 0.6 2.4 2 1 0 2 2 2 1 Kinesin motor domain DUF4250 PF14056.1 EEB06570.2 - 0.0069 16.0 1.5 0.024 14.3 1.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4250) HSP70 PF00012.15 EEB06571.1 - 1.2e-265 882.1 10.1 1.4e-265 881.9 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB06571.1 - 4.1e-14 51.9 2.5 2.7e-12 45.9 0.4 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EEB06571.1 - 0.0029 17.2 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EEB06571.1 - 0.0041 16.9 10.9 0.14 11.9 0.1 4.8 4 2 0 4 4 4 2 Cell division protein FtsA BcrAD_BadFG PF01869.15 EEB06571.1 - 0.011 15.0 0.9 0.52 9.5 0.0 3.1 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 EEB06571.1 - 0.054 12.5 3.0 2.1 7.3 0.1 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase IL31 PF15209.1 EEB06571.1 - 0.18 11.4 1.3 0.65 9.5 0.2 2.1 2 0 0 2 2 2 0 Interleukin 31 5-FTHF_cyc-lig PF01812.15 EEB06572.2 - 3.7e-34 118.1 0.0 4.7e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family F-box-like PF12937.2 EEB06573.1 - 1.8e-10 40.3 0.6 3.7e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEB06573.1 - 2.1e-08 33.6 0.4 3.9e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EEB06573.1 - 9.7e-05 22.1 1.2 0.0025 17.6 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box-like_2 PF13013.1 EEB06573.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain UIM PF02809.15 EEB06573.1 - 0.012 15.1 12.7 0.13 11.8 2.6 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif RIO1 PF01163.17 EEB06574.1 - 2.4e-47 160.7 0.3 4e-47 160.0 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 EEB06574.1 - 1.1e-32 111.9 0.0 2.2e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EEB06574.1 - 1.4e-11 44.5 0.1 5.5e-05 23.0 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEB06574.1 - 4.7e-07 29.0 0.0 4.3e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEB06574.1 - 0.0047 16.1 0.1 0.011 14.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Acetyltransf_1 PF00583.19 EEB06575.1 - 7e-09 35.6 0.0 1.3e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB06575.1 - 1.6e-07 31.3 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB06575.1 - 2e-06 27.9 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB06575.1 - 4.7e-06 26.4 0.1 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB06575.1 - 8.2e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 EEB06575.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1904 PF08921.6 EEB06575.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) DNA_mis_repair PF01119.14 EEB06576.1 - 1.2e-29 102.1 0.0 2.1e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEB06576.1 - 2.2e-10 40.3 0.0 4.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEB06576.1 - 2.4e-08 33.6 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Diphtheria_C PF02763.9 EEB06576.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain CAF1-p150_C2 PF15539.1 EEB06576.1 - 0.16 11.0 0.6 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Arm PF00514.18 EEB06577.1 - 0.00011 21.8 12.1 0.0005 19.7 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEB06577.1 - 0.00019 21.6 4.2 0.21 11.8 0.0 5.0 3 2 3 6 6 6 2 HEAT repeats ARID PF01388.16 EEB06578.1 - 5e-13 48.7 0.0 1.3e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HEAT_2 PF13646.1 EEB06578.1 - 0.031 14.5 1.2 0.06 13.6 0.3 1.9 2 0 0 2 2 2 0 HEAT repeats Phage_T4_Gp30_7 PF06919.6 EEB06578.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage Gp30.7 protein Arm PF00514.18 EEB06578.1 - 0.25 11.2 2.7 0.38 10.6 0.5 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat UPF0086 PF01868.11 EEB06579.1 - 5.1e-21 74.1 0.1 7.9e-21 73.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Sld5 PF05916.6 EEB06580.1 - 2.3e-07 31.0 0.3 4.6e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein DUF692 PF05114.8 EEB06580.1 - 0.0013 17.6 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF692) DcpS PF05652.7 EEB06581.1 - 3.8e-29 101.2 1.2 6.5e-29 100.5 0.8 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EEB06581.1 - 5.5e-25 87.8 1.5 9e-25 87.1 1.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Calreticulin PF00262.13 EEB06582.1 - 1.8e-29 102.5 0.0 3.3e-27 95.1 0.0 2.1 1 1 1 2 2 2 2 Calreticulin family Peptidase_S49_N PF08496.5 EEB06583.1 - 0.056 13.2 1.9 2.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Abhydrolase_6 PF12697.2 EEB06584.1 - 1.6e-26 93.6 0.0 2.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB06584.1 - 2.6e-13 49.9 0.0 4.1e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB06584.1 - 5.1e-08 32.7 0.0 4e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEB06584.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EEB06584.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EEB06584.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EEB06584.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 EEB06584.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 EEB06584.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Aconitase PF00330.15 EEB06586.2 - 4.3e-162 539.8 0.0 1.1e-161 538.4 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEB06586.2 - 4e-40 136.9 0.0 7.2e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L21p PF00829.16 EEB06586.2 - 6.4e-07 29.4 0.1 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF521 PF04412.8 EEB06586.2 - 0.012 14.2 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ribosom_S12_S23 PF00164.20 EEB06588.1 - 5.8e-40 135.5 0.6 6.9e-40 135.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Uso1_p115_head PF04869.9 EEB06589.2 - 3.9e-66 222.9 7.4 2.4e-65 220.3 5.1 2.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Reo_sigmaC PF04582.7 EEB06589.2 - 0.8 8.8 30.9 0.15 11.2 3.7 4.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 EEB06589.2 - 2.3 7.6 82.6 0.43 10.0 28.2 5.0 1 1 3 4 4 4 0 Intermediate filament protein PRP3 PF08572.5 EEB06590.1 - 2.7e-62 210.0 15.1 2.7e-62 210.0 10.5 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EEB06590.1 - 7.1e-36 122.7 0.1 7.1e-36 122.7 0.0 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) ApoO PF09769.4 EEB06590.1 - 0.016 14.8 1.8 0.016 14.8 1.2 2.6 3 0 0 3 3 3 0 Apolipoprotein O DUF3810 PF12725.2 EEB06590.1 - 0.078 11.8 0.1 0.078 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Lactamase_B_2 PF12706.2 EEB06591.2 - 1.4e-17 63.9 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEB06591.2 - 2e-09 37.3 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 EEB06592.2 - 2.6e-41 141.4 50.3 2.6e-41 141.4 34.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB06592.2 - 1.5e-13 49.8 28.9 2.4e-13 49.1 20.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEB06592.2 - 6.2e-13 48.1 12.0 6.2e-13 48.1 8.3 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter CLTH PF10607.4 EEB06593.1 - 1.9e-14 53.6 1.2 2.2e-14 53.3 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEB06593.1 - 3.5e-14 52.2 5.0 3.5e-14 52.2 3.5 3.3 3 0 0 3 3 3 1 RING-type zinc-finger FCH PF00611.18 EEB06593.1 - 0.022 14.9 0.3 0.051 13.7 0.2 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.9 EEB06593.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EEB06593.1 - 0.1 10.9 0.5 0.14 10.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C3HC4_4 PF15227.1 EEB06593.1 - 5.3 6.9 9.3 0.21 11.5 1.3 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEB06593.1 - 7.6 6.2 11.5 0.57 9.8 3.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) THUMP PF02926.12 EEB06594.2 - 4.8e-20 71.9 0.6 2.3e-19 69.7 0.1 2.2 1 1 1 2 2 2 1 THUMP domain DUF1690 PF07956.6 EEB06595.1 - 1.4e-23 83.4 10.7 1.6e-23 83.2 7.4 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) SF-assemblin PF06705.6 EEB06595.1 - 0.0083 15.2 9.1 0.012 14.7 6.3 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF4404 PF14357.1 EEB06595.1 - 0.01 16.2 1.8 0.01 16.2 1.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4404) Flu_B_M2 PF04772.7 EEB06595.1 - 0.085 12.9 0.4 0.15 12.1 0.2 1.5 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) MADF_DNA_bdg PF10545.4 EEB06595.1 - 0.087 13.0 0.9 0.15 12.2 0.6 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF445 PF04286.7 EEB06595.1 - 0.12 11.8 4.1 0.17 11.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FCH PF00611.18 EEB06595.1 - 0.39 10.9 8.1 0.84 9.8 0.4 2.5 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF342 PF03961.8 EEB06595.1 - 2.9 6.1 7.9 3.4 5.9 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RICH PF05062.7 EEB06595.1 - 3.1 7.9 8.6 1.3 9.1 0.6 2.8 1 1 2 3 3 3 0 RICH domain Snapin_Pallidin PF14712.1 EEB06595.1 - 3.4 8.0 10.8 0.49 10.7 1.3 2.5 1 1 1 2 2 2 0 Snapin/Pallidin CorA PF01544.13 EEB06596.1 - 8.4e-07 28.2 4.1 2e-06 27.1 2.8 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2800 PF10926.3 EEB06596.1 - 0.064 12.3 0.2 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Tim17 PF02466.14 EEB06597.1 - 9.6e-40 135.5 8.2 1.2e-39 135.3 5.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tachystatin_B PF11478.3 EEB06597.1 - 0.18 11.5 1.6 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B NAC PF01849.13 EEB06598.1 - 4.7e-17 61.2 2.2 1.7e-16 59.4 0.2 2.4 3 0 0 3 3 3 1 NAC domain UBA PF00627.26 EEB06598.1 - 0.00012 21.8 0.2 0.00028 20.6 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ketoacyl-synt_C PF02801.17 EEB06598.1 - 0.0094 15.7 1.2 0.016 15.0 0.3 1.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PocR PF10114.4 EEB06598.1 - 0.016 14.3 0.3 0.13 11.4 0.0 2.0 1 1 1 2 2 2 0 Sensory domain found in PocR DUF442 PF04273.8 EEB06598.1 - 0.35 10.7 2.6 0.66 9.8 1.8 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) YIF1 PF03878.10 EEB06599.1 - 8.2e-89 296.8 4.0 9.5e-89 296.6 2.8 1.0 1 0 0 1 1 1 1 YIF1 eIF-1a PF01176.14 EEB06600.1 - 4.3e-28 96.5 0.3 6e-28 96.0 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Helicase_C_2 PF13307.1 EEB06601.2 - 6.1e-51 172.6 0.0 1.1e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEB06601.2 - 1.1e-46 158.3 0.2 2e-46 157.5 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Vps51 PF08700.6 EEB06602.1 - 1.6e-15 56.7 0.0 2.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 ABC_trans_N PF14510.1 EEB06602.1 - 0.14 12.2 1.1 0.37 10.8 0.7 1.8 1 1 1 2 2 2 0 ABC-transporter extracellular N-terminal Glyco_transf_20 PF00982.16 EEB06603.1 - 2.6e-140 468.0 0.1 4.2e-140 467.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEB06603.1 - 5.5e-63 212.0 0.0 8.7e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EEB06603.1 - 1.6e-08 34.4 0.0 4.7e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EEB06603.1 - 0.013 15.6 0.0 0.093 12.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEB06603.1 - 0.021 14.2 0.0 0.36 10.2 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 Evr1_Alr PF04777.8 EEB06604.1 - 3.8e-26 90.8 1.6 3.8e-26 90.8 1.1 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Gemini_AL2 PF01440.11 EEB06604.1 - 0.022 14.8 0.9 0.034 14.2 0.6 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein Ima1_N PF09779.4 EEB06604.1 - 0.4 11.1 4.2 0.86 10.1 2.4 1.9 2 1 0 2 2 2 0 Ima1 N-terminal domain XPG_N PF00752.12 EEB06605.1 - 8.4e-37 125.4 0.0 1.8e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEB06605.1 - 2.8e-29 100.9 0.1 5.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EEB06605.1 - 6.8e-05 23.0 0.0 0.00023 21.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CheD PF03975.8 EEB06605.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Mpv17_PMP22 PF04117.7 EEB06606.2 - 2.4e-24 84.7 4.2 2.4e-24 84.7 2.9 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family RRM_1 PF00076.17 EEB06607.1 - 3.7e-28 96.9 1.0 1.7e-17 62.8 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06607.1 - 3.3e-25 87.8 0.1 1.9e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06607.1 - 1.9e-07 30.8 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Maf PF02545.9 EEB06608.1 - 5.4e-50 169.2 0.0 6.8e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DSS1_SEM1 PF05160.8 EEB06609.1 - 5.1e-20 71.0 14.6 5.5e-20 70.9 10.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4624 PF15417.1 EEB06609.1 - 0.0072 15.9 3.1 0.0096 15.5 1.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4624) SNF2_N PF00176.18 EEB06610.1 - 1.1e-73 247.6 1.8 2e-73 246.8 1.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EEB06610.1 - 1.4e-29 102.2 2.0 3.4e-29 101.0 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EEB06610.1 - 1.2e-24 85.7 5.3 1.2e-12 47.2 1.3 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EEB06610.1 - 1.5e-14 53.6 0.0 4.9e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB06610.1 - 0.00027 20.4 0.0 0.00055 19.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 EEB06610.1 - 0.0031 17.2 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain FF PF01846.14 EEB06611.1 - 4.2e-38 129.0 16.4 1.4e-13 50.5 0.1 6.3 6 0 0 6 6 6 5 FF domain WW PF00397.21 EEB06611.1 - 1.9e-18 65.9 13.5 1.7e-10 40.5 2.4 3.3 2 0 0 2 2 2 2 WW domain Mesothelin PF06060.7 EEB06611.1 - 0.024 12.6 0.0 0.035 12.1 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DUF348 PF03990.9 EEB06611.1 - 0.041 13.4 0.1 0.22 11.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF348) Med3 PF11593.3 EEB06611.1 - 5.2 6.1 12.0 11 5.1 8.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ATP_bind_1 PF03029.12 EEB06612.1 - 1.2e-84 283.6 0.0 1.3e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EEB06612.1 - 0.0031 16.9 0.0 0.0066 15.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EEB06612.1 - 0.0044 16.7 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEB06612.1 - 0.017 14.9 0.0 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EEB06612.1 - 0.038 14.8 0.1 0.11 13.2 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_31 PF13614.1 EEB06612.1 - 0.063 13.2 0.1 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEB06612.1 - 0.072 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein GTP_EFTU PF00009.22 EEB06612.1 - 0.11 11.9 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1746 PF08508.5 EEB06614.1 - 1.8e-15 56.8 7.3 2.6e-15 56.3 5.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Fijivirus_P9-2 PF06837.6 EEB06614.1 - 7.9 5.5 14.8 7.8 5.5 9.5 1.4 1 1 0 1 1 1 0 Fijivirus P9-2 protein Spt20 PF12090.3 EEB06615.1 - 4.1e-40 137.0 11.5 7e-40 136.3 0.0 2.9 2 1 0 2 2 2 1 Spt20 family NICE-3 PF07406.6 EEB06615.1 - 0.27 10.7 2.7 1 8.7 0.0 2.7 3 0 0 3 3 3 0 NICE-3 protein NTP_transferase PF00483.18 EEB06616.2 - 3.3e-12 46.2 0.0 5.4e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EEB06616.2 - 1.7e-07 30.3 13.1 0.019 14.4 1.2 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEB06616.2 - 0.00015 21.8 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEB06616.2 - 0.0029 17.1 18.5 0.042 13.4 0.7 4.5 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EEB06616.2 - 0.052 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.7 EEB06616.2 - 0.097 11.2 0.6 0.17 10.4 0.4 1.3 1 0 0 1 1 1 0 L-fucokinase OPT PF03169.10 EEB06617.1 - 2.9e-192 640.4 47.4 3.4e-192 640.2 32.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GATase_2 PF00310.16 EEB06618.1 - 4.4e-26 91.4 0.0 3.1e-20 72.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEB06618.1 - 1.9e-15 56.9 0.0 3.7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEB06618.1 - 3.9e-15 55.6 0.0 6.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EEB06618.1 - 1.4e-10 40.9 0.1 4.4e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EEB06618.1 - 8.6e-07 27.9 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_3 PF15610.1 EEB06618.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Dynein_light PF01221.13 EEB06619.2 - 2.7e-41 139.4 0.1 3.3e-41 139.1 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.6 EEB06619.2 - 0.041 13.5 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Ectatomin HTH_33 PF13592.1 EEB06619.2 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix SpoIIIAH PF12685.2 EEB06619.2 - 0.095 12.1 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein LRR_4 PF12799.2 EEB06620.1 - 5.9e-17 60.8 20.1 1.7e-10 40.2 1.8 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB06620.1 - 4.3e-14 52.0 17.3 1e-08 34.7 4.7 4.6 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EEB06620.1 - 6.3e-07 28.8 16.0 0.54 10.4 0.1 6.3 5 1 1 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.28 EEB06620.1 - 2.1e-06 26.9 24.5 0.0066 16.3 0.2 7.2 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EEB06620.1 - 5.3e-05 22.7 23.2 0.28 11.5 0.0 7.6 7 0 0 7 7 7 3 Leucine rich repeat LRR_9 PF14580.1 EEB06620.1 - 0.00032 20.3 0.2 0.00066 19.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat HSP90 PF00183.13 EEB06621.1 - 5.5e-258 856.6 32.0 6.8e-258 856.3 22.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EEB06621.1 - 8.7e-12 44.8 0.3 8.7e-12 44.8 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEB06621.1 - 2.6e-11 43.1 0.0 4.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_7 PF13499.1 EEB06622.1 - 2.8e-11 43.3 0.5 7.7e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEB06622.1 - 1.2e-10 40.3 0.8 1.1e-07 31.0 0.3 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EEB06622.1 - 1.3e-09 36.6 0.9 1.9e-08 32.9 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EEB06622.1 - 6.1e-06 25.3 0.9 1.6e-05 24.0 0.6 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EEB06622.1 - 8.6e-05 22.0 5.2 0.0077 15.8 0.3 2.5 2 1 1 3 3 3 2 EF-hand domain pair Glycos_trans_3N PF02885.12 EEB06622.1 - 0.007 15.9 0.4 0.033 13.7 0.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain UPF0158 PF03682.8 EEB06622.1 - 0.052 13.1 1.0 0.077 12.6 0.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF1027 PF06265.6 EEB06622.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) DUF853 PF05872.7 EEB06622.1 - 0.085 11.1 0.2 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TPR_11 PF13414.1 EEB06623.1 - 1.3e-15 56.7 6.4 0.00012 21.6 1.1 5.5 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.1 EEB06623.1 - 2.5e-08 33.4 5.2 0.011 15.8 0.2 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06623.1 - 7.3e-08 32.2 7.4 6.3e-05 22.8 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06623.1 - 9.3e-07 28.9 3.2 0.078 13.6 0.0 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06623.1 - 3.6e-06 27.2 7.1 0.22 11.8 0.1 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEB06623.1 - 4.9e-06 25.9 11.0 1.3 8.7 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06623.1 - 7.3e-06 26.5 5.0 0.0081 16.8 0.5 4.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB06623.1 - 3.7e-05 23.3 11.8 1.4 8.9 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06623.1 - 0.00014 22.0 0.7 9.1 6.9 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06623.1 - 0.00077 19.0 5.7 0.31 10.9 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EEB06623.1 - 0.0059 16.7 6.8 6.4 6.9 0.1 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EEB06623.1 - 0.0071 16.2 1.1 0.1 12.5 0.1 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 EEB06623.1 - 0.012 15.3 8.4 37 4.4 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat LMWPc PF01451.16 EEB06624.1 - 8.6e-40 136.2 0.0 9.6e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Flavin_Reduct PF01613.13 EEB06625.1 - 2.9e-27 95.4 1.1 7.9e-27 94.0 0.8 1.6 1 1 0 1 1 1 1 Flavin reductase like domain TraI PF07057.6 EEB06625.1 - 0.032 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA helicase TraI E1-E2_ATPase PF00122.15 EEB06626.1 - 2.2e-58 196.9 6.0 2.2e-58 196.9 4.2 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEB06626.1 - 1.6e-24 87.5 0.0 3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB06626.1 - 4.4e-13 49.8 0.0 9.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEB06626.1 - 1.3e-08 34.1 0.0 2.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEB06626.1 - 0.0018 17.9 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB06626.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DnaJ PF00226.26 EEB06627.1 - 4.1e-20 71.2 5.1 1.3e-19 69.6 3.5 1.9 1 0 0 1 1 1 1 DnaJ domain GatB_Yqey PF02637.13 EEB06627.1 - 0.15 11.7 4.9 0.16 11.6 0.3 2.2 1 1 1 2 2 2 0 GatB domain Rotamase PF00639.16 EEB06627.1 - 2.5 8.8 8.9 4.7 8.0 2.7 2.6 1 1 0 2 2 2 0 PPIC-type PPIASE domain Cut8_N PF14482.1 EEB06627.1 - 2.8 8.0 5.1 3 7.9 0.2 2.5 2 0 0 2 2 2 0 Cut8 proteasome-binding domain FAD_binding_2 PF00890.19 EEB06628.1 - 6.8e-127 423.7 3.7 8.4e-127 423.4 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEB06628.1 - 2.6e-47 159.9 0.4 3.7e-47 159.3 0.3 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEB06628.1 - 8e-07 29.1 0.0 0.0032 17.3 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEB06628.1 - 2.3e-06 26.7 1.5 0.0077 15.1 1.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EEB06628.1 - 4e-05 22.8 0.2 0.018 14.1 0.0 2.6 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EEB06628.1 - 0.00015 20.7 0.8 0.0036 16.2 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEB06628.1 - 0.0052 15.8 0.2 0.0094 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEB06628.1 - 0.12 12.4 0.2 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEB06628.1 - 0.23 9.9 3.4 0.46 8.8 0.8 2.5 3 0 0 3 3 3 0 HI0933-like protein SpoIIE PF07228.7 EEB06629.1 - 4.5e-14 52.6 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EEB06629.1 - 3.6e-12 46.2 0.1 5.2e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEB06629.1 - 2.1e-05 24.0 0.0 6.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C dCMP_cyt_deam_1 PF00383.17 EEB06630.1 - 9.5e-18 63.7 0.8 1.1e-17 63.4 0.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EEB06630.1 - 6.7e-10 39.0 0.5 5.2e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EEB06630.1 - 8.6e-05 21.9 0.6 0.033 13.5 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ecTbetaR2 PF08917.5 EEB06630.1 - 0.12 12.0 0.2 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Cgr1 PF03879.9 EEB06631.2 - 1.8e-27 95.6 30.9 1.9e-27 95.5 21.5 1.0 1 0 0 1 1 1 1 Cgr1 family DUF4407 PF14362.1 EEB06631.2 - 1.2 7.9 7.8 1.5 7.7 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRISPR_Cas2 PF09827.4 EEB06631.2 - 6 7.0 6.3 1.3 9.2 1.1 2.2 1 1 0 2 2 2 0 CRISPR associated protein Cas2 DNA_repr_REX1B PF14966.1 EEB06632.2 - 1.8e-07 31.4 8.0 2.5e-07 30.9 3.0 2.1 1 1 1 2 2 2 1 DNA repair REX1-B Med10 PF09748.4 EEB06632.2 - 0.0015 18.3 1.4 0.09 12.5 0.1 2.2 1 1 1 2 2 2 1 Transcription factor subunit Med10 of Mediator complex DUF342 PF03961.8 EEB06632.2 - 0.0069 14.8 9.9 0.008 14.6 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Med21 PF11221.3 EEB06632.2 - 0.02 14.8 1.8 0.02 14.8 1.2 2.8 2 1 1 3 3 3 0 Subunit 21 of Mediator complex DUF2294 PF10057.4 EEB06632.2 - 0.039 13.6 0.2 0.039 13.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2294) HsbA PF12296.3 EEB06632.2 - 0.051 13.4 2.3 0.19 11.6 0.3 2.2 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Syntaxin PF00804.20 EEB06632.2 - 0.089 12.9 14.1 0.12 12.5 9.1 1.7 1 1 0 1 1 1 0 Syntaxin WXG100 PF06013.7 EEB06632.2 - 0.093 12.7 8.5 1.9 8.5 0.2 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Laminin_II PF06009.7 EEB06632.2 - 0.14 11.9 9.5 0.16 11.7 3.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Endotoxin_N PF03945.9 EEB06632.2 - 0.18 11.1 5.8 0.23 10.8 3.8 1.4 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain TBPIP PF07106.8 EEB06632.2 - 0.36 10.3 16.9 0.12 11.8 7.8 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EEB06632.2 - 0.38 9.7 13.0 0.59 9.1 9.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3287 PF11690.3 EEB06632.2 - 0.44 10.6 3.9 3 7.9 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Vac_Fusion PF02346.11 EEB06632.2 - 0.46 9.9 3.9 0.65 9.4 0.7 2.6 2 1 0 2 2 1 0 Chordopoxvirus fusion protein PspA_IM30 PF04012.7 EEB06632.2 - 0.55 9.5 14.5 0.32 10.3 0.5 2.7 2 1 1 3 3 3 0 PspA/IM30 family Baculo_PEP_C PF04513.7 EEB06632.2 - 0.72 9.6 10.0 7.9 6.2 4.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zwint PF15556.1 EEB06632.2 - 0.78 8.9 14.2 0.7 9.1 8.6 1.6 1 1 1 2 2 2 0 ZW10 interactor NEMO PF11577.3 EEB06632.2 - 0.89 9.3 7.5 0.42 10.4 1.3 2.8 2 1 1 3 3 3 0 NF-kappa-B essential modulator NEMO FlaC_arch PF05377.6 EEB06632.2 - 0.89 9.4 9.4 0.79 9.6 1.2 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EEB06632.2 - 1.3 8.8 8.6 0.91 9.3 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2746 PF10874.3 EEB06632.2 - 1.3 9.2 6.1 3.6 7.8 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2746) TMF_DNA_bd PF12329.3 EEB06632.2 - 1.3 8.8 19.5 0.65 9.8 2.2 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Flagellin_N PF00669.15 EEB06632.2 - 1.8 8.3 8.8 0.78 9.5 3.3 2.1 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region SSFA2_C PF14723.1 EEB06632.2 - 2.1 8.0 12.7 6.9 6.3 8.8 1.8 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF3007 PF11460.3 EEB06632.2 - 3.5 7.7 11.7 0.24 11.4 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3007) Snapin_Pallidin PF14712.1 EEB06632.2 - 3.9 7.8 16.8 2.1 8.7 5.0 2.8 1 1 2 3 3 3 0 Snapin/Pallidin IncA PF04156.9 EEB06632.2 - 4 6.9 21.1 32 4.0 14.6 2.1 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EEB06632.2 - 4.7 7.2 14.6 4.9 7.2 2.1 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1824 PF08854.5 EEB06632.2 - 5.4 6.6 9.4 9.9 5.8 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1824) YlqD PF11068.3 EEB06632.2 - 7.4 6.6 18.8 0.56 10.2 7.7 2.1 1 1 1 2 2 2 0 YlqD protein Ribosomal_L31e PF01198.14 EEB06633.1 - 5.8e-37 125.2 2.0 7.4e-37 124.8 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e SbcCD_C PF13558.1 EEB06634.2 - 7e-10 38.7 0.0 2.2e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.9 EEB06634.2 - 8.2e-08 31.5 0.1 8.2e-08 31.5 0.1 6.2 7 1 0 7 7 7 1 Rad50 zinc hook motif Reo_sigmaC PF04582.7 EEB06634.2 - 6.1e-05 22.3 8.0 6.1e-05 22.3 5.5 5.7 2 2 3 6 6 6 2 Reovirus sigma C capsid protein MscS_porin PF12795.2 EEB06634.2 - 0.0012 18.1 15.7 0.0012 18.1 10.9 6.8 3 2 4 8 8 8 1 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EEB06634.2 - 0.002 16.7 117.2 0.032 12.6 0.0 6.4 3 2 2 6 6 6 3 AAA domain Laminin_II PF06009.7 EEB06634.2 - 0.0064 16.2 3.7 0.0064 16.2 2.6 9.8 4 2 5 10 10 10 1 Laminin Domain II DUF3618 PF12277.3 EEB06634.2 - 0.17 11.9 3.0 1.3 9.1 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SPRY PF00622.23 EEB06635.2 - 1.5e-23 83.2 0.7 2.6e-23 82.4 0.5 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EEB06635.2 - 1.9e-16 60.0 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEB06635.2 - 0.00086 18.9 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 LisH UQ_con PF00179.21 EEB06636.2 - 2.4e-48 163.1 0.1 3.2e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EEB06636.2 - 0.00034 20.2 0.1 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EEB06636.2 - 0.0027 17.5 0.1 0.0053 16.6 0.0 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EEB06636.2 - 0.026 14.2 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.20 EEB06637.1 - 8.7e-67 224.9 0.0 1.2e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06637.1 - 6.7e-28 97.4 0.0 1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06637.1 - 1.8e-06 27.1 0.0 3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB06637.1 - 0.027 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATA PF00320.22 EEB06638.1 - 1.8e-14 52.8 5.2 3.6e-14 51.7 3.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Cpn10 PF00166.16 EEB06639.1 - 9e-26 89.6 0.0 1e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pex24p PF06398.6 EEB06640.1 - 2e-24 86.0 6.0 3.7e-24 85.1 4.2 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Arrestin_N PF00339.24 EEB06641.1 - 1.1e-19 70.7 0.0 2.5e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEB06641.1 - 3e-18 66.2 0.0 1.7e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.20 EEB06643.1 - 1.8e-31 109.3 1.3 2.2e-31 109.0 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB06643.1 - 2.8e-13 49.9 0.3 3.7e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB06643.1 - 7.7e-12 45.4 0.2 9.5e-12 45.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEB06643.1 - 2.4e-05 23.3 2.1 3.4e-05 22.8 1.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEB06643.1 - 8.7e-05 22.2 0.6 0.00018 21.2 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEB06643.1 - 0.0053 16.2 0.2 0.0074 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_1 PF00667.15 EEB06645.1 - 2.9e-67 226.3 0.0 4.7e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEB06645.1 - 2.5e-09 37.6 0.0 2.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEB06645.1 - 0.0042 17.1 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain GBP_repeat PF02526.9 EEB06645.1 - 0.13 11.6 0.1 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Glycophorin-binding protein Copper-fist PF00649.13 EEB06646.1 - 2.9e-19 67.9 1.5 6.2e-19 66.9 1.1 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Ran-binding PF05508.6 EEB06647.1 - 3.5e-83 279.0 1.2 4.4e-83 278.6 0.9 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EEB06648.1 - 8.7e-47 158.9 0.0 1.5e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEB06648.1 - 3.7e-26 91.1 0.3 1.1e-25 89.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEB06648.1 - 3.6e-05 23.7 0.1 9e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB06648.1 - 8.3e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EEB06648.1 - 0.017 13.8 0.3 0.027 13.1 0.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Sec1 PF00995.18 EEB06649.1 - 3.1e-119 399.1 0.6 4.8e-119 398.5 0.5 1.3 1 0 0 1 1 1 1 Sec1 family RPA_C PF08784.6 EEB06650.1 - 3.1e-18 66.0 0.1 6.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EEB06650.1 - 1.1e-05 25.2 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Git3 PF11710.3 EEB06651.1 - 1.9e-40 138.5 19.7 1.9e-40 138.5 13.7 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEB06651.1 - 3.6e-07 29.8 1.1 3.6e-07 29.8 0.8 2.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Inositol_P PF00459.20 EEB06653.1 - 8.1e-52 176.1 0.1 2.7e-51 174.4 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Sigma70_r4 PF04545.11 EEB06653.1 - 0.11 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 zf-C3HC PF07967.8 EEB06654.1 - 4.2e-15 55.6 5.9 6.6e-14 51.8 0.4 2.8 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EEB06654.1 - 8.2e-10 38.4 0.4 8.2e-10 38.4 0.3 3.0 3 0 0 3 3 3 1 Rsm1-like BIR PF00653.16 EEB06654.1 - 0.02 15.2 2.3 0.38 11.2 0.1 2.7 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain PMAIP1 PF15150.1 EEB06654.1 - 0.1 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced TCO89 PF10452.4 EEB06655.2 - 2e-08 33.6 0.2 2e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 TORC1 subunit TCO89 Ribosomal_L37 PF08561.5 EEB06656.1 - 2.1e-20 72.0 1.3 4e-20 71.1 0.9 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 PolyA_pol PF01743.15 EEB06657.1 - 7.9e-21 74.5 0.0 1.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEB06657.1 - 2.3e-07 30.2 0.0 5.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EEB06657.1 - 0.1 12.3 0.2 0.37 10.5 0.0 2.0 3 0 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative MU117 PF15474.1 EEB06658.1 - 9.9e-26 90.0 6.4 1.3e-25 89.7 4.5 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family Carb_bind PF10645.4 EEB06658.1 - 0.09 12.6 3.6 0.13 12.0 0.3 2.5 2 0 0 2 2 2 0 Carbohydrate binding GIY-YIG PF01541.19 EEB06659.1 - 0.099 13.0 0.6 0.099 13.0 0.5 1.9 2 0 0 2 2 2 0 GIY-YIG catalytic domain Parvo_coat PF00740.13 EEB06659.1 - 0.43 9.4 6.1 0.5 9.2 4.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 AbiH PF14253.1 EEB06659.1 - 0.8 9.2 12.2 0.27 10.7 6.4 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH TFIIS_M PF07500.9 EEB06660.2 - 1e-22 80.3 0.3 2.1e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EEB06660.2 - 4.8e-15 56.0 0.0 9.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EEB06660.2 - 8e-12 44.6 6.9 1.3e-11 43.9 4.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB06660.2 - 0.0036 16.5 2.7 0.0061 15.8 1.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EEB06660.2 - 0.1 12.3 1.2 0.23 11.2 0.9 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger zf-RING_2 PF13639.1 EEB06660.2 - 1.3 8.8 4.9 2.4 8.0 3.4 1.4 1 0 0 1 1 1 0 Ring finger domain Mei5 PF10376.4 EEB06661.1 - 2.2e-24 86.2 0.0 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Sel1 PF08238.7 EEB06662.1 - 3.2e-21 75.2 20.4 0.0034 17.9 0.1 8.8 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 EEB06662.1 - 0.01 15.4 4.7 0.77 9.4 0.0 4.2 3 0 0 3 3 3 0 TPR repeat TFIIA PF03153.8 EEB06663.2 - 2e-69 235.2 5.0 3e-69 234.7 3.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ada3 PF10198.4 EEB06664.1 - 2.1e-30 105.1 7.3 5.7e-30 103.7 5.0 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF1676 PF07898.8 EEB06664.1 - 2.7 8.3 8.0 0.13 12.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) SPX PF03105.14 EEB06664.1 - 4.3 7.0 26.1 1.7 8.3 10.1 2.6 1 1 1 2 2 2 0 SPX domain HMG_box_2 PF09011.5 EEB06665.1 - 7.8e-19 67.8 1.5 7.8e-19 67.8 1.0 2.7 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EEB06665.1 - 2.7e-16 59.6 1.7 2.7e-16 59.6 1.2 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box K_channel_TID PF07941.6 EEB06665.1 - 1.3 9.2 14.7 0.75 10.0 1.5 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RNA_pol_Rpb1_1 PF04997.7 EEB06666.1 - 1.1e-126 422.6 0.0 1.7e-126 422.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EEB06666.1 - 6.1e-109 363.5 0.1 9.3e-109 362.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEB06666.1 - 9.7e-71 237.0 0.0 2.2e-70 235.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EEB06666.1 - 5.1e-64 215.4 0.4 1e-63 214.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 EEB06666.1 - 1.1e-49 167.6 2.4 2.2e-49 166.6 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 EEB06666.1 - 1.1e-49 168.1 0.0 2.7e-49 166.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEB06666.1 - 5.8e-40 135.3 0.1 1.3e-39 134.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EEB06666.1 - 1.1e-12 46.9 310.1 0.3 11.3 10.3 15.7 4 1 21 25 25 25 21 RNA polymerase Rpb1 C-terminal repeat Pro_isomerase PF00160.16 EEB06667.2 - 7e-47 159.5 0.2 7.7e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Orbi_NS1 PF01718.11 EEB06668.1 - 0.028 12.4 0.1 0.042 11.8 0.1 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Cyclin PF08613.6 EEB06669.2 - 1.5e-10 41.6 0.0 2.9e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEB06669.2 - 0.012 15.2 0.8 0.067 12.7 0.6 2.3 1 1 0 1 1 1 0 Cyclin, N-terminal domain RRM_1 PF00076.17 EEB06670.1 - 2.6e-15 55.7 0.0 4.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06670.1 - 5.6e-12 45.4 0.0 8.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEB06670.1 - 9.6e-06 25.9 2.6 9.6e-06 25.9 1.8 2.7 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEB06670.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1639 PF07797.9 EEB06670.1 - 0.11 11.8 2.0 0.2 11.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) Pkinase PF00069.20 EEB06671.1 - 3.5e-69 232.8 0.0 4.5e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06671.1 - 2e-49 168.0 0.0 3.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EEB06671.1 - 1.9e-20 72.7 0.0 3.9e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EEB06671.1 - 5.2e-11 42.5 1.8 7.4e-11 42.0 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEB06671.1 - 9.1e-11 41.4 0.1 9.1e-11 41.4 0.1 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EEB06671.1 - 4.4e-06 25.8 0.0 4.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Ribosomal_L5_C PF00673.16 EEB06672.1 - 3.3e-15 55.5 0.0 5.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEB06672.1 - 4.3e-05 23.2 0.1 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 EST1_DNA_bind PF10373.4 EEB06673.1 - 7.6e-40 136.8 3.6 1.8e-39 135.6 2.5 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EEB06673.1 - 1.6e-15 57.2 1.4 7.8e-15 55.0 0.1 2.8 2 1 0 2 2 2 1 Telomerase activating protein Est1 Ribosomal_L22 PF00237.14 EEB06674.1 - 4.4e-34 116.5 0.1 6.9e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Oxysterol_BP PF01237.13 EEB06675.1 - 3.1e-128 427.2 0.0 8e-128 425.8 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EEB06675.1 - 7.2e-23 80.1 0.3 4.4e-11 42.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB06675.1 - 2e-19 69.7 0.1 3e-09 37.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEB06675.1 - 3.2e-14 51.6 0.1 6.4e-06 25.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EEB06675.1 - 4.2e-14 51.5 0.1 2.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.24 EEB06675.1 - 2.2e-13 50.3 3.2 7e-13 48.6 0.0 3.0 4 0 0 4 4 4 1 PH domain Ank_4 PF13637.1 EEB06675.1 - 4.3e-13 49.3 0.3 0.00011 22.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH_11 PF15413.1 EEB06675.1 - 2.9e-09 37.1 1.9 3.4e-08 33.7 0.0 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EEB06675.1 - 4.7e-08 32.9 0.7 1.3e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3990 PF13151.1 EEB06675.1 - 0.00031 20.1 1.2 0.00075 18.9 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Sin3_corepress PF08295.7 EEB06675.1 - 0.018 14.8 2.3 0.055 13.2 1.6 1.9 1 0 0 1 1 1 0 Sin3 family co-repressor mRNA_cap_enzyme PF01331.14 EEB06677.1 - 2.3e-57 193.8 0.1 3.2e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EEB06677.1 - 8e-29 100.0 0.1 1.4e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EEB06677.1 - 2.6e-06 26.9 0.5 0.00019 20.8 0.0 2.7 2 1 0 2 2 2 1 ATP dependent DNA ligase domain bZIP_1 PF00170.16 EEB06678.1 - 2.5e-09 36.9 12.6 4.8e-09 36.0 8.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEB06678.1 - 6.5e-06 25.8 10.3 1.5e-05 24.6 7.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEB06678.1 - 0.0023 18.2 10.7 0.0049 17.1 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Cep57_MT_bd PF06657.8 EEB06678.1 - 0.63 10.0 5.3 0.27 11.1 0.4 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XET_C PF06955.7 EEB06678.1 - 0.81 9.4 3.9 1 9.1 0.1 2.7 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus PBP PF01161.15 EEB06679.1 - 6.2e-11 42.3 0.2 1.1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF883 PF05957.8 EEB06681.1 - 0.0093 16.3 18.3 1.2 9.5 4.7 3.1 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EEB06681.1 - 0.017 14.6 10.7 0.03 13.8 7.4 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EEB06681.1 - 0.072 13.4 29.8 0.62 10.4 4.0 3.4 1 1 1 2 2 2 0 YtxH-like protein DUF2959 PF11172.3 EEB06681.1 - 0.1 12.3 11.3 0.016 15.0 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) GEMIN8 PF15348.1 EEB06681.1 - 1.1 9.2 15.7 1.4 8.8 10.9 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 ATP-synt_B PF00430.13 EEB06681.1 - 2.4 7.9 17.8 0.94 9.2 7.0 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) E1-E2_ATPase PF00122.15 EEB06682.1 - 1.2e-14 53.9 0.0 3.3e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EEB06682.1 - 2e-14 54.2 0.0 1.9e-13 51.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB06682.1 - 1.7e-12 47.0 0.0 5.4e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EEB06682.1 - 3.5e-11 43.9 2.0 1.9e-09 38.2 1.4 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEB06682.1 - 0.011 15.2 0.4 0.011 15.2 0.3 2.6 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.1 EEB06682.1 - 0.023 14.6 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) CRF PF00473.12 EEB06682.1 - 0.45 10.6 4.5 0.26 11.4 1.0 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family WH1 PF00568.18 EEB06683.2 - 3.3e-25 87.9 0.0 5.1e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain Corona_nucleoca PF00937.13 EEB06683.2 - 0.039 12.8 5.0 0.062 12.2 3.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NAC PF01849.13 EEB06684.1 - 1.8e-18 65.7 0.5 1.8e-18 65.7 0.4 1.6 2 0 0 2 2 2 1 NAC domain Sod_Fe_C PF02777.13 EEB06685.1 - 5.5e-16 58.3 2.4 1.3e-14 53.8 1.6 2.1 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Beach PF02138.13 EEB06686.2 - 2.2e-106 355.2 0.7 5.7e-106 353.8 0.5 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EEB06686.2 - 8.4e-10 38.4 0.0 3e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EEB06686.2 - 6.2e-05 22.7 7.7 0.039 13.8 0.6 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EEB06686.2 - 9.4e-05 22.6 0.1 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.16 EEB06686.2 - 0.0032 17.3 13.9 0.008 16.0 9.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger FTP PF07504.8 EEB06686.2 - 0.037 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif FYVE_2 PF02318.11 EEB06686.2 - 0.075 12.9 10.6 0.22 11.4 7.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger BAG PF02179.11 EEB06687.1 - 4.3e-16 58.7 0.8 1.1e-15 57.4 0.5 1.7 1 0 0 1 1 1 1 BAG domain DUF837 PF05769.6 EEB06687.1 - 0.0013 18.3 0.2 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF837) Selenoprotein_S PF06936.6 EEB06687.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Dynactin_p62 PF05502.8 EEB06689.2 - 9.1e-17 60.9 33.5 2.4e-12 46.4 19.8 2.3 1 1 1 2 2 2 2 Dynactin p62 family Fungal_trans PF04082.13 EEB06690.2 - 5.1e-25 87.8 1.3 1e-24 86.8 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB06690.2 - 2.2e-11 43.4 10.8 3.6e-11 42.7 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLU PF13236.1 EEB06691.1 - 4.5e-77 258.4 0.1 1.5e-76 256.7 0.0 2.0 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.2 EEB06691.1 - 6.2e-37 127.1 0.0 1.9e-36 125.5 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EEB06691.1 - 1.7e-17 63.1 4.3 1.5e-05 24.8 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.1 EEB06691.1 - 5e-15 55.4 0.4 1.2e-14 54.2 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EEB06691.1 - 1.6e-14 53.2 0.0 0.00019 21.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEB06691.1 - 4.5e-05 22.9 0.8 1 9.0 0.2 4.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEB06691.1 - 0.75 9.4 6.3 0.33 10.6 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TENA_THI-4 PF03070.11 EEB06692.1 - 1.4e-08 34.7 0.5 6.4e-07 29.3 0.0 2.5 1 1 2 3 3 3 2 TENA/THI-4/PQQC family RRN3 PF05327.6 EEB06694.1 - 1.1e-153 512.4 9.1 1.4e-153 511.9 6.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MSC PF09402.5 EEB06695.1 - 1.4e-59 201.4 0.3 2.8e-59 200.4 0.2 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EEB06695.1 - 1.7e-11 43.4 0.1 3.4e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 EEB06695.1 - 0.00064 19.4 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding PNRC PF15365.1 EEB06696.1 - 2.5e-05 24.1 0.2 0.00013 21.9 0.2 2.3 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator SR-25 PF10500.4 EEB06696.1 - 0.79 9.1 20.1 1.3 8.4 13.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 EEB06696.1 - 8.4 4.5 11.7 10 4.2 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CS PF04969.11 EEB06697.1 - 2e-17 63.4 1.8 3.3e-17 62.7 1.3 1.4 1 0 0 1 1 1 1 CS domain LIM_bind PF01803.11 EEB06697.1 - 0.0012 18.0 1.5 0.0016 17.6 1.0 1.2 1 0 0 1 1 1 1 LIM-domain binding protein But2 PF09792.4 EEB06697.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain DUF4404 PF14357.1 EEB06697.1 - 0.031 14.6 1.5 0.067 13.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ox_reductase_C PF08635.5 EEB06697.1 - 0.033 13.6 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal PNPase PF03726.9 EEB06697.1 - 0.062 13.5 0.6 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ABC_tran_2 PF12848.2 EEB06697.1 - 0.27 11.0 4.2 0.44 10.4 2.9 1.3 1 0 0 1 1 1 0 ABC transporter ANTH PF07651.11 EEB06698.1 - 4.2e-62 209.3 0.5 5.5e-62 209.0 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EEB06698.1 - 8e-10 38.6 0.3 2e-09 37.3 0.2 1.7 1 0 0 1 1 1 1 ENTH domain SNase PF00565.12 EEB06699.1 - 2.4e-20 72.8 0.0 3.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SPC12 PF06645.8 EEB06700.2 - 3.2e-15 55.7 0.0 4.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribosomal_L1 PF00687.16 EEB06701.1 - 1.9e-38 132.0 7.7 2.5e-38 131.6 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ldh_1_C PF02866.13 EEB06702.1 - 5.5e-43 146.7 0.0 8.1e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EEB06702.1 - 2.7e-39 134.1 0.4 3.9e-39 133.7 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEB06702.1 - 0.00069 18.4 0.0 0.00098 17.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEB06702.1 - 0.023 14.9 0.4 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CAP_N PF01213.14 EEB06703.1 - 1.2e-106 356.5 11.9 1.2e-106 356.5 8.3 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EEB06703.1 - 6.6e-60 201.0 7.1 9.4e-60 200.5 4.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EEB06703.1 - 6.3e-05 22.3 7.7 8.6e-05 21.9 4.6 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C PLDc_2 PF13091.1 EEB06704.1 - 0.012 15.4 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 PLD-like domain Spc97_Spc98 PF04130.8 EEB06705.1 - 3.9e-13 48.5 18.0 2.9e-10 39.0 2.9 2.2 1 1 1 2 2 2 2 Spc97 / Spc98 family PB1 PF00564.19 EEB06705.1 - 0.018 14.7 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 PB1 domain UK PF02512.9 EEB06706.1 - 0.045 14.1 0.0 0.055 13.8 0.0 1.1 1 0 0 1 1 1 0 Virulence determinant SAS4 PF15460.1 EEB06707.1 - 0.054 13.3 0.7 0.58 10.0 0.0 2.6 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 EF-hand_7 PF13499.1 EEB06708.1 - 5e-25 87.4 12.1 1.9e-12 47.1 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEB06708.1 - 5.9e-25 84.6 19.0 2.8e-07 29.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EEB06708.1 - 2.1e-22 76.9 12.5 2.2e-07 30.1 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEB06708.1 - 8.7e-13 46.9 16.2 6.1e-05 22.1 0.1 4.6 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.1 EEB06708.1 - 2.3e-12 46.3 15.9 1.1e-08 34.5 0.8 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EEB06708.1 - 1.8e-09 37.3 0.6 0.00085 19.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEB06708.1 - 1e-05 25.2 4.0 0.015 15.0 0.5 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand MerR-DNA-bind PF09278.6 EEB06708.1 - 0.12 12.7 2.3 0.8 10.1 0.1 2.7 2 1 0 2 2 2 0 MerR, DNA binding DUF2963 PF11178.3 EEB06708.1 - 0.45 9.9 1.9 11 5.4 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) Med3 PF11593.3 EEB06709.1 - 0.0016 17.7 10.0 0.002 17.4 7.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal REV PF00424.13 EEB06709.1 - 0.0061 16.4 0.2 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) SOBP PF15279.1 EEB06709.1 - 0.26 11.6 17.7 0.38 11.0 12.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 EEB06709.1 - 0.59 8.1 9.9 1 7.3 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 EEB06709.1 - 1.3 7.3 12.6 1.8 6.8 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SSP160 PF06933.6 EEB06709.1 - 3.9 5.3 26.1 5.6 4.8 18.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF605 PF04652.11 EEB06709.1 - 4.8 6.4 22.6 6.5 6.0 15.7 1.1 1 0 0 1 1 1 0 Vta1 like MCM PF00493.18 EEB06710.2 - 7e-100 334.0 0.3 3.4e-50 170.7 0.0 2.3 1 1 1 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 EEB06710.2 - 4e-19 69.2 0.1 1.2e-18 67.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain DUF1675 PF07897.6 EEB06710.2 - 5.7 6.7 14.2 10 5.9 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) UCR_UQCRX_QCR9 PF05365.7 EEB06711.2 - 8.7e-24 82.9 0.5 9.6e-24 82.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like WD40 PF00400.27 EEB06712.2 - 1.6e-05 24.5 0.4 0.00018 21.2 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat RNA_pol_N PF01194.12 EEB06713.1 - 1.3e-31 108.3 0.5 1.5e-31 108.1 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit SHMT PF00464.14 EEB06714.1 - 3.2e-203 674.4 0.0 3.7e-203 674.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EEB06714.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase CHCH PF06747.8 EEB06715.1 - 4e-06 26.5 1.1 5.7e-06 26.0 0.8 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EEB06715.1 - 0.0048 16.6 0.1 0.0062 16.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like OTU PF02338.14 EEB06716.1 - 3.2e-09 37.4 0.0 6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Septin PF00735.13 EEB06717.2 - 1.3e-84 283.5 0.0 2.3e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEB06717.2 - 2.6e-06 27.3 0.0 5.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEB06717.2 - 0.00016 21.2 0.4 0.00036 20.0 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 EEB06717.2 - 0.0006 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Ras family DUF258 PF03193.11 EEB06717.2 - 0.015 14.4 0.0 0.038 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EEB06717.2 - 0.017 14.2 0.9 0.028 13.5 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EEB06717.2 - 0.044 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 EEB06717.2 - 0.049 12.8 0.2 0.049 12.8 0.2 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EEB06717.2 - 0.05 13.0 1.1 2.2 7.6 0.3 3.0 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Abi_2 PF07751.6 EEB06717.2 - 0.28 11.3 7.1 0.1 12.7 2.4 2.1 2 0 0 2 2 2 0 Abi-like protein DUF1212 PF06738.7 EEB06718.2 - 2.2e-42 144.7 15.1 1.8e-39 135.2 0.4 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEB06718.2 - 2.2e-22 79.3 29.9 4e-22 78.5 8.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) PC4 PF02229.11 EEB06719.1 - 4.4e-21 73.8 0.4 7e-21 73.2 0.2 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Tankyrase_bdg_C PF15327.1 EEB06719.1 - 8.4 6.5 12.9 0.7 10.0 0.6 2.2 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain Clathrin PF00637.15 EEB06720.2 - 0.001 18.6 4.7 0.001 18.6 3.2 2.9 2 0 0 2 2 2 1 Region in Clathrin and VPS DZR PF12773.2 EEB06720.2 - 0.024 14.4 5.7 0.02 14.7 1.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.1 EEB06720.2 - 0.59 9.9 6.0 2.5 8.0 4.2 2.2 1 0 0 1 1 1 0 Ring finger domain Auto_anti-p27 PF06677.7 EEB06720.2 - 1 9.1 4.9 9.3 6.1 0.2 3.4 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_2 PF13923.1 EEB06720.2 - 7.4 6.6 10.7 14 5.8 4.9 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 EEB06721.2 - 1e-48 164.7 0.0 1.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB06721.2 - 1.3e-11 45.0 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB06721.2 - 9.5e-07 28.2 0.0 2e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB06721.2 - 0.0024 17.0 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEB06721.2 - 0.026 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EEB06721.2 - 0.038 14.2 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DASH_Dad1 PF08649.5 EEB06722.1 - 1.2e-22 79.3 2.4 1.5e-22 79.0 1.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 EEB06722.1 - 0.0083 16.0 0.7 0.011 15.5 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 zf-Nse PF11789.3 EEB06723.1 - 2.5e-20 71.7 0.9 5.1e-20 70.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EEB06723.1 - 0.0003 20.2 1.4 0.00052 19.4 0.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Nucleo_P87 PF07267.6 EEB06723.1 - 0.00071 18.3 0.7 0.00071 18.3 0.5 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 zf-RING_UBOX PF13445.1 EEB06723.1 - 0.02 14.6 2.8 0.069 12.8 1.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Rtf2 PF04641.7 EEB06723.1 - 0.16 11.1 0.1 0.16 11.1 0.0 2.0 2 1 0 2 2 2 0 Rtf2 RING-finger XhlA PF10779.4 EEB06723.1 - 0.23 11.4 0.3 0.23 11.4 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA COG2 PF06148.6 EEB06723.1 - 0.23 11.3 6.0 0.23 11.3 1.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SbcD_C PF12320.3 EEB06723.1 - 0.41 10.7 9.1 0.1 12.6 4.0 1.8 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain FlaC_arch PF05377.6 EEB06723.1 - 1.8 8.5 6.5 0.77 9.7 0.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Myb_DNA-binding PF00249.26 EEB06724.2 - 0.0066 16.4 0.1 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med13_C PF06333.7 EEB06725.1 - 6.2e-16 57.9 2.0 1.2e-15 57.0 0.3 2.2 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal Ndc1_Nup PF09531.5 EEB06726.1 - 6.2 5.1 7.4 7.1 4.9 5.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tom37_C PF11801.3 EEB06727.1 - 0.00029 20.7 1.7 0.34 10.7 0.3 2.2 1 1 1 2 2 2 2 Tom37 C-terminal domain Pox_VP8_L4R PF04498.7 EEB06727.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R GST_C_3 PF14497.1 EEB06727.1 - 0.098 13.1 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2419 PF10343.4 EEB06728.1 - 2.4e-112 374.9 0.1 2.8e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Pho88 PF10032.4 EEB06729.1 - 1.6e-62 210.1 0.0 2e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.27 EEB06730.2 - 2.8e-09 36.4 0.0 0.0071 16.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEB06730.2 - 0.0017 17.7 0.0 2.8 7.5 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Epimerase PF01370.16 EEB06731.1 - 3.7e-50 170.5 0.0 4.9e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEB06731.1 - 6.2e-27 93.3 0.1 1.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EEB06731.1 - 4.4e-16 58.4 0.0 3.5e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEB06731.1 - 1.2e-12 47.4 0.0 3.1e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEB06731.1 - 5.2e-11 42.7 0.0 9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEB06731.1 - 8.9e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEB06731.1 - 1.2e-08 34.2 0.0 3.8e-07 29.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EEB06731.1 - 7.1e-08 32.3 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EEB06731.1 - 7.9e-08 31.5 0.0 1.2e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EEB06731.1 - 0.0001 21.6 0.1 0.00026 20.3 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EEB06731.1 - 0.0015 17.9 0.2 0.0027 17.1 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EEB06731.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.14 EEB06731.1 - 0.038 13.5 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short_C2 PF13561.1 EEB06731.1 - 0.052 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 EEB06731.1 - 0.059 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DapB_N PF01113.15 EEB06731.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2278 PF10042.4 EEB06732.1 - 0.25 11.0 1.2 5.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) Wbp11 PF09429.5 EEB06732.1 - 0.39 10.7 2.2 2.2 8.3 0.0 2.9 2 1 0 2 2 2 0 WW domain binding protein 11 DASH_Dam1 PF08653.5 EEB06732.1 - 1.6 8.5 3.9 31 4.4 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Sirohm_synth_C PF14823.1 EEB06733.1 - 1.5e-17 62.6 0.0 2.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EEB06733.1 - 4.9e-16 58.8 0.5 3.5e-15 56.1 0.3 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EEB06733.1 - 8.9e-16 56.5 0.5 1.5e-15 55.8 0.4 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pkinase PF00069.20 EEB06734.1 - 1.2e-66 224.5 0.0 2.2e-66 223.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06734.1 - 1.9e-42 145.1 0.0 2.9e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EEB06734.1 - 1.9e-20 72.3 24.7 3.4e-10 39.4 4.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EEB06734.1 - 1.8e-17 62.8 8.9 6e-12 45.1 0.9 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EEB06734.1 - 3.1e-08 34.0 0.4 1.4e-07 31.8 0.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 EEB06734.1 - 0.0013 18.4 0.3 0.0029 17.4 0.2 1.5 1 0 0 1 1 1 1 C2 domain Prok-RING_1 PF14446.1 EEB06734.1 - 0.0087 15.7 7.1 0.0087 15.7 4.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Methyltrans_RNA PF04452.9 EEB06734.1 - 0.027 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase V-SNARE PF05008.10 EEB06734.1 - 2.3 8.4 8.5 6.7 6.9 1.4 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4452 PF14618.1 EEB06735.1 - 1.4e-13 51.0 0.8 1.7e-13 50.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) IBN_N PF03810.14 EEB06736.1 - 5.2e-11 42.2 1.5 2.7e-10 40.0 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EEB06736.1 - 9.6e-09 34.2 1.7 0.0017 17.0 0.0 3.3 3 0 0 3 3 3 2 Cse1 HEAT_2 PF13646.1 EEB06736.1 - 1.2e-05 25.5 0.4 0.046 14.0 0.0 5.1 4 2 1 5 5 5 1 HEAT repeats CAS_CSE1 PF03378.10 EEB06736.1 - 0.001 17.4 7.8 0.0012 17.2 2.4 2.9 1 1 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 EEB06736.1 - 0.0024 17.7 6.4 0.04 13.8 0.4 5.0 3 2 1 4 4 4 1 Exportin 1-like protein HEAT_EZ PF13513.1 EEB06736.1 - 0.11 12.9 1.5 5.4e+02 1.2 0.0 6.1 7 0 0 7 7 7 0 HEAT-like repeat Metallophos PF00149.23 EEB06737.2 - 1.9e-43 148.1 0.5 2.3e-43 147.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clp1 PF06807.9 EEB06738.1 - 1.7e-22 80.1 0.0 1.5e-21 77.0 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEB06738.1 - 2.4e-07 30.5 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EEB06738.1 - 0.001 18.6 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EEB06738.1 - 0.0012 18.8 0.0 0.0061 16.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.1 EEB06738.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EEB06738.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EEB06738.1 - 0.046 12.9 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEB06738.1 - 0.056 12.9 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EEB06738.1 - 0.086 12.2 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEB06738.1 - 0.1 12.3 0.0 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 EEB06738.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SH3_1 PF00018.23 EEB06739.1 - 4e-29 99.7 0.0 2.5e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EEB06739.1 - 5.4e-18 64.3 0.1 1.5e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EEB06739.1 - 1.9e-16 59.2 0.1 1.2e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EEB06739.1 - 1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EEB06739.1 - 1.3e-06 27.9 0.1 2.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF2417 PF10329.4 EEB06740.1 - 8.4e-42 143.1 2.3 1.2e-41 142.6 1.6 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EEB06740.1 - 2.4e-18 66.8 4.2 6.6e-18 65.4 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB06740.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB06740.1 - 0.00047 19.7 0.0 0.00075 19.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4395 PF14340.1 EEB06740.1 - 1.4 8.9 6.8 3.3 7.8 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) DUF2975 PF11188.3 EEB06740.1 - 5.4 6.7 10.2 0.16 11.6 2.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) CBFD_NFYB_HMF PF00808.18 EEB06742.1 - 3.6e-28 97.3 0.4 4.9e-28 96.9 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB06742.1 - 4.2e-08 33.1 0.0 6.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EEB06742.1 - 0.0035 17.1 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EEB06742.1 - 0.006 16.2 0.1 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated PAN_3 PF08277.7 EEB06742.1 - 0.029 14.0 0.2 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain CENP-S PF15630.1 EEB06742.1 - 0.13 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S tRNA-synt_2c PF01411.14 EEB06743.1 - 7.3e-218 724.3 0.0 1.2e-217 723.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEB06743.1 - 6.2e-19 67.6 0.3 1.3e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EEB06743.1 - 1.5e-07 30.9 0.0 5.9e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 DHHA1 domain HVSL PF09749.4 EEB06744.2 - 1.7e-39 135.3 0.3 1.9e-39 135.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.20 EEB06745.1 - 4.1e-57 193.3 0.0 4.7e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06745.1 - 1.7e-20 73.1 0.0 2.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB06745.1 - 6.7e-07 29.2 0.0 2.1e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEB06745.1 - 0.0076 15.8 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EEB06745.1 - 0.063 12.3 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEB06745.1 - 0.064 12.5 0.1 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL P53_tetramer PF07710.6 EEB06745.1 - 0.078 12.0 0.0 4.9 6.3 0.0 2.7 2 0 0 2 2 2 0 P53 tetramerisation motif APC_CDC26 PF10471.4 EEB06747.1 - 8.2e-14 52.1 0.1 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Cation_efflux PF01545.16 EEB06748.1 - 4e-73 245.9 7.3 4.7e-73 245.7 5.1 1.0 1 0 0 1 1 1 1 Cation efflux family NDUF_C2 PF06374.6 EEB06748.1 - 0.14 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Sin3_corepress PF08295.7 EEB06749.2 - 8.1e-37 125.0 0.2 2.6e-36 123.4 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.16 EEB06749.2 - 6.7e-14 51.2 7.2 0.00047 19.7 0.0 3.8 3 1 0 3 3 3 3 Paired amphipathic helix repeat Pkinase PF00069.20 EEB06750.1 - 1.2e-73 247.4 0.4 3.7e-73 245.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06750.1 - 6.8e-43 146.6 0.0 1.1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EEB06750.1 - 3.2e-32 110.3 0.3 1.7e-16 59.9 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EEB06750.1 - 4.2e-08 32.4 0.0 1.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEB06750.1 - 0.0059 15.6 0.1 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB06750.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4524 PF15025.1 EEB06750.1 - 0.023 14.2 0.0 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) LETM1 PF07766.8 EEB06751.2 - 3.8e-95 317.9 0.2 5.4e-95 317.4 0.2 1.2 1 0 0 1 1 1 1 LETM1-like protein ORC6 PF05460.8 EEB06751.2 - 0.00087 18.4 1.5 0.0015 17.7 1.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Barstar PF01337.13 EEB06751.2 - 0.044 13.6 0.1 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Barstar (barnase inhibitor) MutS_V PF00488.16 EEB06752.1 - 4.1e-84 281.6 0.3 1.1e-83 280.2 0.1 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EEB06752.1 - 1.2e-58 198.3 0.1 3.2e-58 196.8 0.1 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEB06752.1 - 5.5e-19 68.2 0.0 1.5e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEB06752.1 - 6.4e-12 45.7 0.1 3.4e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 EEB06752.1 - 0.039 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEB06752.1 - 0.042 14.1 0.4 3.6 7.8 0.0 3.2 3 0 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 EEB06752.1 - 0.045 13.6 0.0 0.16 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EEB06752.1 - 0.15 12.3 6.0 0.39 11.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain TAFII55_N PF04658.8 EEB06753.1 - 6.9e-56 188.2 0.3 6.9e-56 188.2 0.2 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region NOA36 PF06524.7 EEB06753.1 - 7 5.8 10.7 11 5.1 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein Adaptin_N PF01602.15 EEB06754.1 - 5.8e-112 374.6 8.1 7e-112 374.4 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EEB06754.1 - 2.4e-20 72.9 0.2 1.5e-19 70.3 0.0 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain cwf18 PF08315.7 EEB06755.1 - 1.3e-33 116.2 8.0 1.6e-33 115.8 5.5 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Cytochrom_C_2 PF01322.15 EEB06755.1 - 0.42 11.1 4.1 0.2 12.2 1.0 1.7 2 0 0 2 2 2 0 Cytochrome C' Ribosomal_S8e PF01201.17 EEB06756.1 - 6.9e-37 126.5 12.6 5.5e-36 123.6 8.7 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 EEB06756.1 - 4.3 6.5 12.8 0.11 11.8 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) Ank_5 PF13857.1 EEB06757.1 - 4e-17 61.8 0.2 4.9e-14 52.0 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEB06757.1 - 4.4e-16 58.9 0.1 5.7e-09 36.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB06757.1 - 3.8e-13 49.5 0.0 7.3e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEB06757.1 - 2.3e-11 42.8 0.8 4.5e-09 35.6 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EEB06757.1 - 1.9e-10 39.9 0.0 4.6e-07 29.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat CPL PF08144.6 EEB06758.1 - 2e-22 79.6 0.0 2.2e-21 76.2 0.0 2.8 2 1 0 2 2 2 1 CPL (NUC119) domain DUF2890 PF11081.3 EEB06758.1 - 7.7e-05 22.8 18.6 7.7e-05 22.8 12.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) TraD PF06412.6 EEB06758.1 - 0.0011 18.4 0.3 0.28 10.7 0.0 2.9 2 0 0 2 2 2 1 Conjugal transfer protein TraD Caldesmon PF02029.10 EEB06758.1 - 0.023 13.1 29.7 0.035 12.5 20.6 1.2 1 0 0 1 1 1 0 Caldesmon SAPS PF04499.10 EEB06758.1 - 0.03 12.9 7.2 0.049 12.2 5.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EEB06758.1 - 0.077 11.4 27.9 0.12 10.8 19.4 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EEB06758.1 - 0.82 8.8 31.8 1.5 7.9 22.0 1.4 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 EEB06758.1 - 1.2 7.1 12.9 2.5 6.1 9.0 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T PF15511.1 EEB06758.1 - 3.3 6.8 23.3 5.2 6.2 16.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 EEB06758.1 - 7.8 5.4 42.6 14 4.6 29.5 1.4 1 0 0 1 1 1 0 BUD22 Formyl_trans_N PF00551.14 EEB06759.1 - 6.1e-44 149.7 0.2 7.1e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase GBP_C PF02841.9 EEB06760.1 - 1.1 8.4 7.1 1.1 8.3 4.9 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Peptidase_M41 PF01434.13 EEB06761.2 - 1e-70 237.5 0.4 1.5e-70 237.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEB06761.2 - 2.6e-42 144.1 0.0 6.7e-42 142.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB06761.2 - 2.2e-06 27.8 0.9 0.0014 18.8 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEB06761.2 - 1.7e-05 24.9 0.5 0.00082 19.4 0.7 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEB06761.2 - 1.7e-05 25.5 0.0 5.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEB06761.2 - 2e-05 23.4 0.0 4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EEB06761.2 - 0.00013 21.7 0.0 0.00031 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEB06761.2 - 0.00026 20.6 0.1 0.001 18.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EEB06761.2 - 0.00038 19.5 0.0 0.00085 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EEB06761.2 - 0.00044 19.6 2.1 0.011 15.0 0.2 2.7 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EEB06761.2 - 0.00078 18.6 1.2 0.0095 15.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEB06761.2 - 0.0011 18.4 0.0 0.003 16.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EEB06761.2 - 0.0014 18.6 0.1 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB06761.2 - 0.0038 17.5 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEB06761.2 - 0.0038 16.8 2.5 0.15 11.6 0.1 3.1 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.1 EEB06761.2 - 0.008 16.0 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEB06761.2 - 0.012 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EEB06761.2 - 0.017 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EEB06761.2 - 0.019 14.9 0.0 0.086 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEB06761.2 - 0.03 13.2 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KaiC PF06745.8 EEB06761.2 - 0.16 11.0 0.1 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 KaiC ATP-synt_D PF01813.12 EEB06762.1 - 1e-62 211.1 5.0 1e-62 211.1 3.4 2.3 2 0 0 2 2 2 1 ATP synthase subunit D EXOSC1 PF10447.4 EEB06763.1 - 1.5e-24 85.7 2.6 2.2e-24 85.2 1.8 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EEB06763.1 - 0.011 14.9 0.6 0.044 13.0 0.4 2.1 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EEB06763.1 - 0.073 13.1 1.4 0.58 10.2 1.0 2.1 1 1 0 1 1 1 0 S1 RNA binding domain LSM PF01423.17 EEB06764.1 - 5.1e-17 61.1 0.1 7.1e-17 60.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain NAD_binding_10 PF13460.1 EEB06765.1 - 2.9e-11 43.7 0.0 4.3e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEB06765.1 - 5.7e-07 29.2 0.2 2e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEB06765.1 - 2e-05 23.4 0.0 0.00012 20.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEB06765.1 - 8e-05 22.0 0.0 0.00017 20.9 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EEB06765.1 - 0.00016 21.6 0.2 0.00085 19.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEB06765.1 - 0.00029 19.8 0.0 0.012 14.5 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.15 EEB06765.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EEB06765.1 - 0.0032 16.4 0.1 2.1 7.2 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein NdhO PF11910.3 EEB06765.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Saccharop_dh PF03435.13 EEB06765.1 - 0.015 14.2 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Formyl_trans_N PF00551.14 EEB06765.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Formyl transferase WD40 PF00400.27 EEB06766.2 - 3.1e-17 61.7 1.5 0.00078 19.2 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EEB06766.2 - 0.0019 17.7 0.1 0.15 11.4 0.0 2.3 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EEB06766.2 - 0.0022 16.8 0.2 0.082 11.6 0.1 2.8 1 1 0 2 2 2 1 Nup133 N terminal like PQQ PF01011.16 EEB06766.2 - 0.0074 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat Fucose_iso_N1 PF07881.7 EEB06766.2 - 0.0083 15.6 0.1 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 L-fucose isomerase, first N-terminal domain CRT10 PF08728.5 EEB06766.2 - 0.16 9.9 3.6 0.21 9.5 0.0 2.5 3 0 0 3 3 3 0 CRT10 RNB PF00773.14 EEB06767.2 - 1.5e-43 149.3 0.4 2.3e-43 148.7 0.3 1.2 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EEB06767.2 - 0.021 14.3 0.2 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain CBFD_NFYB_HMF PF00808.18 EEB06768.1 - 4.9e-13 48.9 0.9 6.4e-13 48.5 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB06768.1 - 2.8e-10 40.1 0.3 3.2e-10 39.9 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EEB06768.1 - 0.0065 16.2 0.6 0.012 15.3 0.4 1.5 1 1 1 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIID_30kDa PF03540.8 EEB06768.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Glucosamine_iso PF01182.15 EEB06769.1 - 4.7e-61 205.9 0.0 5.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAM110_C PF14160.1 EEB06769.1 - 0.07 14.0 1.3 0.088 13.7 0.1 1.7 2 0 0 2 2 2 0 Centrosome-associated C terminus Pkinase PF00069.20 EEB06770.1 - 7.1e-75 251.4 0.0 8.1e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06770.1 - 6.6e-36 123.7 0.0 8.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06770.1 - 0.0013 17.7 0.0 0.003 16.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEB06770.1 - 0.021 14.5 0.1 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB06770.1 - 0.026 13.3 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Acetyltransf_1 PF00583.19 EEB06771.2 - 1.9e-13 50.2 0.0 2.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEB06771.2 - 3.2e-05 24.0 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB06771.2 - 0.0002 21.0 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EEB06771.2 - 0.00025 21.1 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB06771.2 - 0.0015 18.3 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEB06771.2 - 0.0027 17.6 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L11_N PF03946.9 EEB06772.1 - 6.5e-17 60.7 0.1 9.6e-17 60.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEB06772.1 - 7.9e-12 45.1 0.5 1.8e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EEB06772.1 - 0.045 13.3 0.0 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region TPR_11 PF13414.1 EEB06773.1 - 9.8e-22 76.3 42.8 7.6e-06 25.4 0.7 8.4 6 3 1 8 8 8 6 TPR repeat TPR_2 PF07719.12 EEB06773.1 - 2.6e-16 58.1 34.8 0.029 14.2 1.4 12.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06773.1 - 6.5e-15 53.7 29.2 0.00025 20.5 0.8 9.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06773.1 - 5.3e-14 51.9 35.4 0.0014 18.4 0.3 9.6 7 2 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06773.1 - 8e-14 50.9 17.4 0.015 15.8 0.0 9.8 8 2 3 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06773.1 - 2.8e-13 50.0 18.9 0.00022 21.4 0.0 8.5 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06773.1 - 1.3e-12 48.0 22.6 0.0006 20.4 0.1 7.6 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06773.1 - 3.4e-09 36.5 15.2 0.094 13.2 0.4 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06773.1 - 7.2e-09 34.7 19.1 0.079 12.7 0.4 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEB06773.1 - 1e-08 34.4 36.0 0.0048 16.4 0.7 10.5 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEB06773.1 - 1.1e-07 31.4 14.2 0.19 12.0 0.0 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEB06773.1 - 2.1e-06 27.4 13.5 1.6 8.7 0.6 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EEB06773.1 - 4.2e-05 23.5 25.3 0.047 13.8 0.4 7.3 5 2 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEB06773.1 - 0.013 15.3 20.1 2 8.3 0.2 7.0 6 1 2 8 8 8 0 Tetratricopeptide repeat DUF2722 PF10846.3 EEB06774.1 - 0.028 13.4 1.9 0.038 13.0 0.7 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2722) ESX-1_EspG PF14011.1 EEB06774.1 - 0.11 11.7 0.2 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 EspG family Rhomboid_SP PF12595.3 EEB06774.1 - 0.72 9.4 7.6 0.82 9.2 1.1 2.4 3 0 0 3 3 3 0 Rhomboid serine protease Ribosomal_L2_C PF03947.13 EEB06775.1 - 9.8e-48 161.2 0.4 1.7e-47 160.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEB06775.1 - 8.7e-27 92.9 0.2 8.7e-27 92.9 0.1 2.3 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain DUF2414 PF10309.4 EEB06776.2 - 3e-15 55.6 0.0 5.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) SMC_N PF02463.14 EEB06777.1 - 1.4e-64 217.3 3.7 1.9e-64 216.9 2.5 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEB06777.1 - 1.2e-29 102.7 0.1 3.6e-28 97.9 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEB06777.1 - 2.7e-15 57.1 1.4 1.8e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEB06777.1 - 2.1e-08 34.7 84.5 0.00036 20.9 28.3 5.7 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EEB06777.1 - 2.4e-06 26.9 0.0 6.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EEB06777.1 - 6.7e-05 22.1 19.5 6.7e-05 22.1 13.5 7.1 3 2 2 6 6 6 3 Growth-arrest specific micro-tubule binding SbcCD_C PF13558.1 EEB06777.1 - 0.0074 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EEB06777.1 - 0.015 15.5 0.0 0.015 15.5 0.0 5.9 4 3 0 4 4 4 0 ABC transporter XPG_N PF00752.12 EEB06778.1 - 1.1e-31 109.0 0.0 2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEB06778.1 - 1.3e-21 76.4 0.0 2.7e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EEB06778.1 - 0.14 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing ELYS PF13934.1 EEB06779.1 - 5.3e-57 193.1 5.3 6.8e-57 192.8 3.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly TPR_2 PF07719.12 EEB06779.1 - 0.76 9.8 3.5 77 3.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Filamin PF00630.14 EEB06780.1 - 0.039 14.5 0.6 3.6 8.2 0.0 3.6 4 0 0 4 4 4 0 Filamin/ABP280 repeat FAM86 PF14904.1 EEB06780.1 - 0.17 11.6 0.1 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function Glyco_hydro_72 PF03198.9 EEB06781.1 - 7.2e-128 425.9 9.5 9.3e-128 425.6 6.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEB06781.1 - 5e-16 58.9 4.2 5e-16 58.9 2.9 1.9 2 0 0 2 2 2 1 X8 domain CAF1 PF04857.15 EEB06782.1 - 4.1e-36 124.6 0.0 8.4e-36 123.6 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease Amidohydro_2 PF04909.9 EEB06782.1 - 0.034 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase DNA_pol_A_exo1 PF01612.15 EEB06782.1 - 0.08 12.4 0.1 0.98 8.8 0.0 2.4 2 1 0 2 2 2 0 3'-5' exonuclease Pkinase PF00069.20 EEB06783.1 - 5.8e-75 251.7 0.0 7.1e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06783.1 - 8.3e-47 159.4 0.0 1.1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06783.1 - 1.9e-09 36.8 0.0 9.5e-08 31.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEB06783.1 - 1.4e-05 24.3 0.0 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEB06783.1 - 0.0015 17.8 0.4 0.022 14.1 0.2 2.3 2 1 0 2 2 2 1 RIO1 family APH PF01636.18 EEB06783.1 - 0.024 14.3 0.6 0.35 10.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEB06783.1 - 0.027 13.8 0.2 0.07 12.4 0.2 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.4 EEB06784.2 - 1.5e-64 216.6 6.2 1.7e-64 216.4 4.3 1.0 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 EEB06784.2 - 0.0038 16.7 0.2 0.0047 16.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase toxin 2 Type_III_YscG PF09477.5 EEB06784.2 - 0.041 13.9 0.3 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) SprT-like PF10263.4 EEB06784.2 - 0.3 10.7 6.7 0.59 9.7 3.9 2.0 1 1 0 1 1 1 0 SprT-like family Peptidase_M13 PF01431.16 EEB06784.2 - 0.77 8.9 5.0 0.49 9.5 2.1 1.7 1 1 1 2 2 2 0 Peptidase family M13 UPF0113 PF03657.8 EEB06785.1 - 1.2e-10 41.2 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EEB06785.1 - 0.043 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 PUA domain SRP72 PF08492.7 EEB06786.1 - 3.5e-12 46.4 4.0 7.9e-12 45.3 2.8 1.6 1 0 0 1 1 1 1 SRP72 RNA-binding domain Apc3 PF12895.2 EEB06786.1 - 1.4e-06 28.2 10.1 0.18 11.9 0.1 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB06786.1 - 5.4e-05 23.0 7.3 8.5e-05 22.4 0.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06786.1 - 0.00015 22.0 3.1 6 7.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06786.1 - 0.01 16.2 10.9 4.4 7.9 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEB06786.1 - 0.013 15.1 12.3 0.1 12.2 0.5 4.3 5 0 0 5 5 5 0 TPR repeat TPR_20 PF14561.1 EEB06786.1 - 0.079 13.0 1.3 1.6 8.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06786.1 - 0.62 10.4 8.7 11 6.3 1.4 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat Ferrochelatase PF00762.14 EEB06787.2 - 3e-94 315.5 0.0 3.6e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase DUF914 PF06027.7 EEB06788.1 - 3e-122 407.6 20.5 3.6e-122 407.4 14.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EEB06788.1 - 4.1e-07 30.1 5.7 4.1e-07 30.1 3.9 3.2 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EEB06788.1 - 5.5e-06 26.4 8.5 5.5e-06 26.4 5.9 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EEB06788.1 - 0.0015 17.5 22.8 0.0031 16.4 15.8 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEB06788.1 - 0.0087 15.7 7.5 0.0087 15.7 5.2 2.8 2 2 0 2 2 2 1 Triose-phosphate Transporter family RRM_1 PF00076.17 EEB06789.2 - 1.4e-15 56.6 0.1 2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06789.2 - 1.4e-05 25.0 0.0 0.00041 20.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) R3H-assoc PF13902.1 EEB06790.1 - 0.05 13.5 0.2 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 R3H-associated N-terminal domain Gln-synt_C PF00120.19 EEB06791.1 - 6.1e-32 110.7 0.0 8.4e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain But2 PF09792.4 EEB06792.1 - 1.6e-35 121.9 3.3 2.4e-35 121.3 2.3 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Reticulon PF02453.12 EEB06793.1 - 2.1e-29 102.2 3.6 4.1e-29 101.3 2.5 1.5 1 0 0 1 1 1 1 Reticulon DUF732 PF05305.9 EEB06793.1 - 0.07 13.2 0.8 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Senescence PF06911.7 EEB06793.1 - 0.18 11.4 1.3 0.46 10.1 0.1 2.0 2 0 0 2 2 2 0 Senescence-associated protein Hamartin PF04388.7 EEB06793.1 - 0.41 9.2 5.2 0.46 9.1 3.6 1.2 1 0 0 1 1 1 0 Hamartin protein adh_short PF00106.20 EEB06795.1 - 8.2e-32 110.4 0.1 1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB06795.1 - 1.5e-14 54.0 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB06795.1 - 1.7e-12 47.6 0.2 2.1e-12 47.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEB06795.1 - 7.6e-05 22.4 0.5 0.00017 21.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EEB06795.1 - 0.00023 20.1 2.0 0.00042 19.3 1.4 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GTP_EFTU PF00009.22 EEB06796.2 - 3.2e-57 193.0 0.8 5.1e-57 192.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEB06796.2 - 5.1e-32 109.9 0.0 1.4e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEB06796.2 - 1.7e-16 60.1 8.7 4.7e-16 58.6 1.6 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEB06796.2 - 5.1e-05 22.8 0.9 5.1e-05 22.8 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEB06796.2 - 0.00097 19.0 0.3 0.0032 17.4 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 EEB06797.1 - 1.3e-14 53.5 0.0 1.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06797.1 - 1e-12 47.8 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06797.1 - 8.9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEB06797.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Ribosomal_L34e PF01199.13 EEB06798.1 - 7.5e-38 128.6 2.7 9.8e-38 128.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e zf-C3HC4 PF00097.20 EEB06799.1 - 4.2e-06 26.3 7.7 1.4e-05 24.6 5.4 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06799.1 - 1.2e-05 24.9 6.8 2.2e-05 24.0 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEB06799.1 - 4.6e-05 23.1 7.8 7.8e-05 22.4 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EEB06799.1 - 0.00017 21.3 4.3 0.00017 21.3 3.0 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEB06799.1 - 0.00024 21.0 8.0 0.00068 19.6 5.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB06799.1 - 0.00095 18.7 9.0 0.0016 18.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB06799.1 - 0.0046 16.6 3.4 0.01 15.5 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EEB06799.1 - 0.013 15.6 2.2 0.023 14.8 1.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EEB06799.1 - 0.46 10.0 3.4 0.72 9.4 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 EEB06800.1 - 2.1e-71 240.1 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06800.1 - 1.1e-30 106.5 0.0 2.1e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEB06800.1 - 0.0002 20.7 2.5 0.00025 20.4 0.7 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EEB06800.1 - 0.00021 20.3 1.9 0.087 11.7 0.1 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EEB06800.1 - 0.035 13.8 0.3 0.39 10.3 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB06800.1 - 0.044 12.8 1.1 0.14 11.1 0.5 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3317 PF11779.3 EEB06801.1 - 1.2e-13 50.2 3.1 1.5e-13 49.9 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2838 PF10998.3 EEB06801.1 - 0.041 13.7 0.6 0.045 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Glyco_hydro_47 PF01532.15 EEB06802.1 - 4.1e-129 431.1 0.0 5.3e-129 430.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EEB06802.1 - 0.11 10.7 0.0 0.19 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Pribosyltran PF00156.22 EEB06803.1 - 3.6e-20 71.9 0.0 4.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEB06803.1 - 0.095 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Metallophos PF00149.23 EEB06804.2 - 1.5e-14 53.8 1.9 2.7e-14 53.0 1.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AMO PF02461.11 EEB06804.2 - 0.038 13.7 0.3 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Ammonia monooxygenase GPI-anchored PF10342.4 EEB06805.1 - 7.4e-14 52.0 2.5 7.4e-14 52.0 1.7 3.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_transf_20 PF00982.16 EEB06806.1 - 3.5e-159 530.2 0.6 6.8e-158 526.0 0.4 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEB06806.1 - 1e-82 276.6 0.0 1.6e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EEB06806.1 - 1.1e-05 25.0 0.0 0.072 12.6 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PIP5K PF01504.13 EEB06807.1 - 2.1e-83 279.3 0.0 3e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase polyprenyl_synt PF00348.12 EEB06809.1 - 1.1e-07 30.9 0.1 1.4e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EEB06809.1 - 0.0011 18.4 0.4 0.0021 17.5 0.3 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF1059 PF06348.6 EEB06809.1 - 0.17 11.7 1.1 0.52 10.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) COQ9 PF08511.6 EEB06810.1 - 3.1e-24 84.2 0.1 6.7e-24 83.2 0.1 1.6 2 0 0 2 2 2 1 COQ9 ER PF01133.12 EEB06811.1 - 1.4e-13 50.4 0.1 2e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S10 PF00450.17 EEB06812.1 - 2.7e-124 415.5 0.2 4.2e-124 414.8 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Aldo_ket_red PF00248.16 EEB06813.1 - 4.5e-45 153.6 0.0 5.5e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LSM PF01423.17 EEB06814.1 - 5.9e-16 57.7 0.0 6.6e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain p450 PF00067.17 EEB06815.1 - 0.011 14.3 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Mito_carr PF00153.22 EEB06816.1 - 1.5e-58 194.5 5.4 2.6e-24 84.7 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Histone PF00125.19 EEB06817.1 - 7.8e-26 90.0 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB06817.1 - 9.9e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HIT PF01230.18 EEB06817.1 - 0.062 13.8 0.0 0.067 13.7 0.0 1.3 1 1 0 1 1 1 0 HIT domain HSP70 PF00012.15 EEB06818.1 - 2.8e-241 801.6 10.9 3.2e-241 801.4 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB06818.1 - 7.4e-18 64.2 1.5 6.8e-17 61.0 0.4 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEB06818.1 - 0.0017 17.5 0.7 0.012 14.7 0.1 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.5 EEB06818.1 - 0.007 15.2 1.3 0.14 10.9 0.1 2.7 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 EEB06818.1 - 0.0093 14.9 0.9 0.022 13.7 0.0 2.1 2 0 0 2 2 2 1 StbA protein RPA PF10134.4 EEB06818.1 - 0.021 14.1 0.2 0.056 12.7 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A FtsA PF14450.1 EEB06818.1 - 0.025 14.3 9.0 0.032 14.0 0.0 3.9 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.11 EEB06818.1 - 0.029 13.9 0.1 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pyrophosphatase PF00719.14 EEB06819.1 - 1.5e-46 157.6 0.0 2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase APG6 PF04111.7 EEB06820.1 - 1.5e-101 339.5 10.3 1.5e-101 339.5 7.1 1.6 2 0 0 2 2 2 1 Autophagy protein Apg6 HNH_5 PF14279.1 EEB06820.1 - 0.0087 16.0 0.2 0.39 10.7 0.0 2.8 2 1 1 3 3 3 1 HNH endonuclease DUF3450 PF11932.3 EEB06820.1 - 0.22 10.7 12.5 0.042 13.1 5.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) KLRAQ PF10205.4 EEB06820.1 - 1.7 8.7 8.7 3.4 7.7 1.7 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 EEB06820.1 - 3.7 7.9 11.4 0.21 11.9 3.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 EEB06820.1 - 9 5.8 15.4 23 4.5 10.7 1.7 1 1 0 1 1 1 0 IncA protein GNAT_acetyltr_2 PF13718.1 EEB06821.1 - 2.8e-80 268.2 0.0 4.9e-80 267.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EEB06821.1 - 2.2e-66 222.8 0.0 5.4e-66 221.5 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EEB06821.1 - 2.7e-40 135.9 0.1 8.6e-40 134.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EEB06821.1 - 1.1e-32 112.1 1.3 2.9e-32 110.7 0.4 2.1 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EEB06821.1 - 0.0036 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB06821.1 - 0.0053 16.7 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SNF2_N PF00176.18 EEB06822.1 - 1.5e-61 207.8 0.2 3.7e-61 206.5 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB06822.1 - 3.8e-13 49.0 0.1 2e-12 46.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PBP1_TM PF14812.1 EEB06822.1 - 0.64 10.3 6.4 2.6 8.4 4.4 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim17 PF02466.14 EEB06823.1 - 9.3e-34 116.2 5.0 1.2e-33 115.9 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 EEB06823.1 - 0.05 13.4 0.5 0.3 10.9 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) DUF2628 PF10947.3 EEB06823.1 - 0.06 13.1 0.1 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) PALP PF00291.20 EEB06824.1 - 4e-54 183.9 0.0 4.7e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PNPOx_C PF10590.4 EEB06825.1 - 6.2e-17 60.8 0.9 6.2e-17 60.8 0.6 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EEB06825.1 - 7.9e-17 61.0 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EEB06825.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4662 PF15578.1 EEB06825.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) PPR_2 PF13041.1 EEB06826.1 - 3e-35 119.9 16.9 1e-11 44.6 0.0 12.4 10 2 5 15 15 15 6 PPR repeat family PPR PF01535.15 EEB06826.1 - 1.9e-27 93.2 19.2 4.2e-05 23.2 0.1 13.4 15 1 0 15 15 15 7 PPR repeat PPR_3 PF13812.1 EEB06826.1 - 3.2e-24 83.1 4.9 0.007 16.5 0.0 12.4 14 0 0 14 14 14 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEB06826.1 - 7.1e-24 82.9 3.8 1.6e-05 24.2 0.0 9.9 11 0 0 11 11 11 5 PPR repeat RPM2 PF08579.6 EEB06826.1 - 0.00028 21.0 0.7 0.003 17.6 0.1 3.1 3 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EEB06826.1 - 0.002 17.4 2.7 1.3 8.3 0.0 4.7 4 1 1 5 5 5 1 Mitochondrial ATPase expression Prefoldin_3 PF13758.1 EEB06826.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit DUF1237 PF06824.6 EEB06827.1 - 2.8e-176 586.2 0.0 3.2e-176 586.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RNase_H2_suC PF08615.6 EEB06828.1 - 3.7e-26 91.5 0.0 4.4e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase PF00069.20 EEB06829.1 - 6.9e-50 169.6 0.0 1.3e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06829.1 - 1.6e-37 128.9 0.0 6.7e-37 126.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EEB06829.1 - 2.9e-11 43.6 0.1 1.1e-10 41.7 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EEB06829.1 - 7.6e-09 34.9 0.0 1.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB06829.1 - 0.11 11.6 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLTH PF10607.4 EEB06830.1 - 4e-24 84.9 1.3 5.2e-24 84.5 0.9 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEB06830.1 - 0.0078 15.9 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 LisH Rapamycin_bind PF08771.6 EEB06830.1 - 0.034 14.2 0.1 0.11 12.6 0.0 1.8 1 1 1 2 2 2 0 Rapamycin binding domain Rad4 PF03835.10 EEB06831.1 - 5.1e-26 90.8 0.0 1.1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEB06831.1 - 6.3e-25 86.6 0.0 3.1e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EEB06831.1 - 5.4e-21 73.8 0.9 1.9e-18 65.7 0.2 2.6 2 0 0 2 2 2 2 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EEB06831.1 - 9.8e-10 38.6 1.4 9.8e-10 38.6 1.0 2.3 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Cellulase PF00150.13 EEB06832.1 - 9.3e-13 48.0 0.4 9.3e-13 48.0 0.3 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FlaC_arch PF05377.6 EEB06833.1 - 0.47 10.3 3.5 12 5.9 0.6 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mito_carr PF00153.22 EEB06834.1 - 1.7e-47 159.0 6.3 2.5e-19 68.7 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC_cobalt PF09819.4 EEB06834.1 - 0.051 13.5 1.1 0.13 12.2 0.0 2.1 2 1 0 2 2 2 0 ABC-type cobalt transport system, permease component ATP_bind_3 PF01171.15 EEB06835.1 - 5.4e-41 140.0 0.0 8.3e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EEB06835.1 - 0.0017 17.8 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Kri1 PF05178.7 EEB06836.1 - 0.23 11.7 1.1 0.72 10.1 0.8 1.8 1 1 0 1 1 1 0 KRI1-like family F-actin_cap_A PF01267.12 EEB06837.1 - 1.7e-62 210.9 3.0 2e-62 210.7 2.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Tox-SHH PF15652.1 EEB06837.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature Sdh5 PF03937.11 EEB06838.1 - 2.9e-23 81.3 0.4 4.1e-23 80.8 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ish1 PF10281.4 EEB06838.1 - 0.38 10.8 3.2 14 5.8 0.0 3.2 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein Peptidase_M24 PF00557.19 EEB06839.2 - 4e-49 167.0 0.2 5.7e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEB06839.2 - 3e-27 94.6 0.0 6.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M10 PF00413.19 EEB06839.2 - 0.042 13.5 0.1 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Matrixin Transglut_core2 PF13369.1 EEB06839.2 - 0.082 12.3 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily TTL PF03133.10 EEB06840.1 - 3.8e-61 206.5 0.9 6.5e-61 205.8 0.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EEB06840.1 - 0.013 15.2 0.0 0.048 13.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EEB06840.1 - 0.014 14.2 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 YheC/D like ATP-grasp WD40 PF00400.27 EEB06841.1 - 4.8e-18 64.2 15.7 7.3e-07 28.8 0.5 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat IKI3 PF04762.7 EEB06841.1 - 0.00033 18.6 0.0 0.0022 15.8 0.0 1.9 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 EEB06841.1 - 0.017 14.8 0.0 0.093 12.4 0.0 2.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Acetyltransf_1 PF00583.19 EEB06842.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF165 PF02592.10 EEB06842.1 - 0.14 12.3 0.1 0.29 11.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 HECT PF00632.20 EEB06843.1 - 1.4e-84 283.9 1.1 2.6e-84 283.1 0.2 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.1 EEB06843.1 - 0.003 17.8 0.0 6.3 7.1 0.0 3.7 4 0 0 4 4 4 2 HEAT repeats Zds_C PF08632.5 EEB06844.1 - 1.4e-27 94.8 3.2 1.8e-27 94.5 1.4 1.8 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pro_dh PF01619.13 EEB06845.1 - 6.4e-43 146.9 0.2 1.1e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Cyt-b5 PF00173.23 EEB06847.1 - 1.8e-06 27.6 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L21e PF01157.13 EEB06847.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L21e NIF PF03031.13 EEB06848.1 - 4e-52 176.0 0.3 8.2e-52 175.0 0.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Uds1 PF15456.1 EEB06848.1 - 6 6.8 10.9 9.4 6.2 0.6 2.3 2 0 0 2 2 2 0 Up-regulated During Septation Sas10 PF09368.5 EEB06849.1 - 1.8e-26 92.1 3.5 4.9e-26 90.7 2.4 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EEB06849.1 - 2.4e-12 46.8 0.0 6.6e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Auto_anti-p27 PF06677.7 EEB06850.1 - 4.9e-15 55.0 1.1 1.1e-14 53.8 0.7 1.6 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HEAT_EZ PF13513.1 EEB06851.1 - 3e-18 65.7 11.3 9.1e-09 35.5 0.0 7.0 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EEB06851.1 - 1.3e-17 62.1 12.4 9.5e-05 22.1 0.0 9.2 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EEB06851.1 - 5.5e-12 45.8 10.5 5.7e-07 29.7 0.0 6.6 3 2 5 8 8 8 3 HEAT repeats IBN_N PF03810.14 EEB06851.1 - 1.2e-11 44.2 4.2 6.9e-11 41.9 0.5 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 EEB06851.1 - 8.3e-08 31.7 12.3 0.0047 16.6 0.0 6.6 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEB06851.1 - 0.00019 20.8 4.3 1.3 8.3 0.0 4.6 3 2 2 5 5 5 2 CLASP N terminal RIX1 PF08167.7 EEB06851.1 - 0.0015 18.2 2.9 1.1 8.9 0.5 4.4 2 1 2 4 4 4 1 rRNA processing/ribosome biogenesis TIP120 PF08623.5 EEB06851.1 - 0.0021 17.6 2.4 0.21 11.1 0.0 3.8 2 1 2 4 4 4 1 TATA-binding protein interacting (TIP20) AP4E_app_platf PF14807.1 EEB06851.1 - 0.043 14.0 0.2 0.18 12.0 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Pkinase PF00069.20 EEB06852.1 - 2.2e-05 23.7 0.0 0.00026 20.2 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Methyltransf_23 PF13489.1 EEB06853.1 - 2.9e-14 53.1 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB06853.1 - 1.5e-13 51.0 0.0 2.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB06853.1 - 6.7e-13 48.5 0.0 9.5e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB06853.1 - 5.3e-11 42.8 0.0 8.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB06853.1 - 3.1e-10 40.6 0.0 5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB06853.1 - 4e-10 39.9 0.0 6.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB06853.1 - 7.6e-05 22.1 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEB06853.1 - 9.3e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEB06853.1 - 9.6e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EEB06853.1 - 0.00085 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EEB06853.1 - 0.0028 17.2 0.0 0.0076 15.9 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.6 EEB06853.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EEB06853.1 - 0.079 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EEB06853.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TRAM_LAG1_CLN8 PF03798.11 EEB06854.1 - 3.1e-38 131.3 17.4 4.1e-38 130.9 12.1 1.1 1 0 0 1 1 1 1 TLC domain DUF4234 PF14018.1 EEB06854.1 - 0.035 13.8 8.0 1.6 8.5 5.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Ni_hydr_CYTB PF01292.15 EEB06854.1 - 0.44 9.9 9.3 1.5 8.1 1.4 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 vATP-synt_AC39 PF01992.11 EEB06855.1 - 1.1e-95 320.6 0.3 1.3e-95 320.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TPR_11 PF13414.1 EEB06856.1 - 1.5e-16 59.8 3.1 4.1e-15 55.1 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEB06856.1 - 3.3e-12 45.4 9.7 1.5e-05 24.4 1.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06856.1 - 4.2e-08 33.4 2.5 6.8e-05 23.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEB06856.1 - 1.3e-07 30.9 9.3 0.00049 19.7 0.4 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06856.1 - 5.1e-06 26.3 4.1 0.012 15.5 1.0 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB06856.1 - 2.4e-05 24.3 5.9 8.8e-05 22.5 3.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EEB06856.1 - 5.2e-05 23.7 4.3 0.0027 18.3 0.1 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat DUF3808 PF10300.4 EEB06856.1 - 0.00019 20.1 2.3 0.00027 19.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 EEB06856.1 - 0.0011 18.5 2.5 0.49 10.2 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06856.1 - 0.0023 18.4 0.5 7.8 7.4 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06856.1 - 0.0033 17.0 0.6 0.092 12.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06856.1 - 0.0074 16.6 0.7 3.5 8.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEB06856.1 - 0.02 15.0 0.4 0.12 12.6 0.0 2.5 2 1 2 4 4 3 0 Tetratricopeptide repeat UxuA PF03786.8 EEB06856.1 - 0.078 11.5 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) TPR_3 PF07720.7 EEB06856.1 - 0.18 11.6 2.0 0.37 10.6 1.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EEB06858.1 - 5.4e-19 67.9 0.6 1.4e-08 34.6 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB06858.1 - 2e-14 53.4 0.3 1.8e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3634 PF12321.3 EEB06858.1 - 0.012 15.5 0.2 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) MBA1 PF07961.6 EEB06859.1 - 5e-26 90.9 0.0 6.4e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Choline_kinase PF01633.15 EEB06860.1 - 1.1e-52 178.6 0.0 1.6e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EEB06860.1 - 1.8e-09 37.6 3.1 4.5e-09 36.3 2.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.9 EEB06860.1 - 5.2e-05 22.6 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus RRM_1 PF00076.17 EEB06861.1 - 2.1e-24 84.9 0.0 1e-11 44.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06861.1 - 1.3e-18 66.7 0.0 2e-08 34.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06861.1 - 6e-18 64.4 0.0 2.8e-10 39.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB06861.1 - 0.00022 20.9 0.0 0.35 10.6 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEB06861.1 - 0.013 15.2 0.0 1 9.1 0.0 2.6 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EEB06861.1 - 0.085 12.7 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 EEB06861.1 - 0.11 12.2 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Citrate_synt PF00285.16 EEB06862.2 - 1e-96 323.8 0.0 1.2e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase MFS_1 PF07690.11 EEB06864.2 - 7.5e-34 116.9 53.9 5.3e-33 114.2 33.8 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB06864.2 - 5.3e-14 51.3 17.2 5.3e-14 51.3 11.9 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEB06864.2 - 3.9e-13 48.7 11.5 3.9e-13 48.7 8.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Shisa PF13908.1 EEB06864.2 - 0.76 9.9 2.4 5.1 7.2 0.4 2.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Neurensin PF14927.1 EEB06864.2 - 8.9 5.6 8.3 1.6 8.1 0.5 3.3 3 1 1 4 4 4 0 Neurensin MPC PF03650.8 EEB06865.2 - 4.9e-36 123.2 0.3 6.1e-36 122.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Sec6 PF06046.8 EEB06866.2 - 2.1e-105 352.9 9.2 2.1e-105 352.9 6.4 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EEB06866.2 - 0.0012 17.7 6.2 0.0045 15.8 4.2 1.9 1 1 1 2 2 2 1 Vps53-like, N-terminal RdRP PF05183.7 EEB06866.2 - 0.023 13.4 1.3 0.036 12.7 0.9 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase TraD_N PF12615.3 EEB06866.2 - 0.099 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 F sex factor protein N terminal WD40 PF00400.27 EEB06867.1 - 3.3e-21 74.2 13.0 5.1e-06 26.1 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat LisH PF08513.6 EEB06867.1 - 2.2e-07 30.3 0.2 2.2e-07 30.3 0.2 2.0 2 0 0 2 2 2 1 LisH DUF3312 PF11768.3 EEB06867.1 - 0.00011 20.6 1.0 0.25 9.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 EEB06867.1 - 0.0034 16.8 0.5 3.7 7.1 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEB06867.1 - 0.0092 13.8 0.4 1.1 6.9 0.0 2.6 3 0 0 3 3 3 2 IKI3 family Coatomer_WDAD PF04053.9 EEB06867.1 - 0.022 13.5 0.0 0.42 9.3 0.0 2.7 2 1 1 3 3 3 0 Coatomer WD associated region DUF1751 PF08551.5 EEB06868.2 - 1.4e-16 60.5 4.4 1.4e-16 60.5 3.1 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EEB06868.2 - 0.0042 17.1 12.5 0.0042 17.1 8.7 1.7 2 0 0 2 2 2 1 Rhomboid family AtpR PF12966.2 EEB06868.2 - 9.3 6.4 12.5 1.6 8.9 2.3 2.9 2 1 0 2 2 2 0 N-ATPase, AtpR subunit CENP-Q PF13094.1 EEB06869.1 - 9.1e-26 90.7 14.8 1.4e-25 90.1 10.2 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4202 PF13875.1 EEB06869.1 - 0.024 14.2 1.2 0.13 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) NPV_P10 PF05531.7 EEB06869.1 - 0.097 12.9 2.2 0.25 11.6 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.10 EEB06869.1 - 0.32 10.6 6.8 0.23 11.1 3.1 1.8 1 1 0 1 1 1 0 Sec34-like family Nsp1_C PF05064.8 EEB06869.1 - 4.3 7.0 9.8 1.7 8.3 0.4 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF904 PF06005.7 EEB06869.1 - 7.7 6.8 17.1 23 5.3 6.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Miro PF08477.8 EEB06870.1 - 2.6e-37 127.9 0.0 3e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EEB06870.1 - 1.3e-28 98.1 1.0 2.3e-28 97.2 0.7 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EEB06870.1 - 1.9e-24 85.1 0.0 8.8e-24 83.0 0.0 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 EEB06870.1 - 4.7e-23 81.3 0.0 2.3e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Ras family AAA_22 PF13401.1 EEB06870.1 - 1.7e-08 34.6 0.0 0.0093 16.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEB06870.1 - 3.9e-08 33.5 0.0 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EEB06870.1 - 3.4e-07 30.2 0.1 0.0018 18.2 0.0 3.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EEB06870.1 - 8.8e-07 28.9 0.5 0.049 13.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEB06870.1 - 3.6e-06 25.8 1.3 0.0094 15.1 0.1 2.9 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.18 EEB06870.1 - 3.6e-06 26.9 1.3 0.0043 16.8 0.0 2.8 3 0 0 3 3 2 2 Dynamin family Arch_ATPase PF01637.13 EEB06870.1 - 5.6e-06 26.2 0.0 0.018 14.7 0.0 2.7 2 1 1 3 3 3 2 Archaeal ATPase EF-hand_6 PF13405.1 EEB06870.1 - 1.1e-05 24.8 2.3 0.0027 17.4 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain DUF258 PF03193.11 EEB06870.1 - 1.5e-05 24.2 0.0 0.011 14.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EEB06870.1 - 3e-05 23.0 0.0 0.23 10.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 EEB06870.1 - 4.1e-05 23.3 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 EEB06870.1 - 4.2e-05 23.0 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Septin PF00735.13 EEB06870.1 - 0.00015 20.9 0.0 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Septin AAA PF00004.24 EEB06870.1 - 0.00017 21.7 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EEB06870.1 - 0.0002 21.6 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter GTP_EFTU PF00009.22 EEB06870.1 - 0.0002 20.8 0.0 0.39 10.1 0.0 3.5 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EEB06870.1 - 0.00022 20.9 0.2 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EEB06870.1 - 0.00026 20.8 0.0 0.039 13.8 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EEB06870.1 - 0.00031 20.3 0.0 0.71 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain EF-hand_8 PF13833.1 EEB06870.1 - 0.00088 18.8 2.2 0.003 17.1 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair Zeta_toxin PF06414.7 EEB06870.1 - 0.0016 17.5 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EEB06870.1 - 0.0018 18.4 0.0 1.9 8.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.1 EEB06870.1 - 0.002 18.5 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 EEB06870.1 - 0.0038 16.5 0.3 0.0038 16.5 0.2 2.0 2 0 0 2 2 1 1 EF hand AAA_17 PF13207.1 EEB06870.1 - 0.0055 17.5 0.1 0.49 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EEB06870.1 - 0.0056 15.9 0.0 0.46 9.6 0.0 3.0 3 1 0 3 3 3 1 ADP-ribosylation factor family Adeno_IVa2 PF02456.10 EEB06870.1 - 0.0068 15.1 0.1 0.71 8.4 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein SMC_N PF02463.14 EEB06870.1 - 0.013 14.7 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEB06870.1 - 0.014 14.7 0.0 5.9 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EEB06870.1 - 0.027 13.5 0.0 0.44 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EEB06870.1 - 0.028 14.2 0.0 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EEB06870.1 - 0.034 14.4 0.0 0.56 10.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EEB06870.1 - 0.035 13.5 0.0 8.9 5.7 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEB06870.1 - 0.039 13.9 0.0 2.8 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain SPARC_Ca_bdg PF10591.4 EEB06870.1 - 0.042 13.8 1.0 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region ATP_bind_1 PF03029.12 EEB06870.1 - 0.044 13.3 0.2 19 4.7 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EEB06870.1 - 0.047 12.9 0.3 21 4.3 0.0 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP-synt_ab PF00006.20 EEB06870.1 - 0.049 13.1 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EEB06870.1 - 0.074 12.4 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein SRPRB PF09439.5 EEB06870.1 - 0.083 12.0 0.0 7.5 5.7 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.13 EEB06870.1 - 0.093 12.2 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EEB06870.1 - 0.11 11.9 0.1 10 5.5 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EEB06870.1 - 0.11 11.8 0.0 7 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain IIGP PF05049.8 EEB06870.1 - 0.11 11.2 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DAP3 PF10236.4 EEB06870.1 - 0.13 11.1 0.5 5.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 EEB06870.1 - 0.14 11.0 0.0 3.6 6.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Zn_clus PF00172.13 EEB06871.1 - 2.1e-09 37.1 8.4 3.5e-09 36.4 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEB06871.1 - 3.1e-09 36.1 3.2 7.4e-09 34.8 2.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain BATS PF06968.8 EEB06874.1 - 5.1e-26 90.3 0.0 1e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EEB06874.1 - 4.2e-16 59.5 0.3 7.2e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Smr PF01713.16 EEB06875.2 - 1.5e-11 44.3 0.0 3.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EEB06875.2 - 3.7e-08 33.2 5.0 3.7e-08 33.2 3.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 EEB06875.2 - 4.3e-06 26.1 0.1 2.2e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 CUE domain PAPS_reduct PF01507.14 EEB06876.1 - 4.1e-34 117.8 0.2 3.9e-33 114.7 0.1 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SNF2_N PF00176.18 EEB06877.1 - 2.6e-60 203.7 0.0 4.3e-60 203.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB06877.1 - 9e-16 57.5 0.2 3.6e-14 52.3 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB06877.1 - 0.0024 18.0 0.0 0.018 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain VMA21 PF09446.5 EEB06878.1 - 4.2e-13 49.0 7.5 5.2e-13 48.7 5.2 1.1 1 0 0 1 1 1 1 VMA21-like domain Silic_transp PF03842.8 EEB06878.1 - 0.0006 18.0 0.7 0.00065 17.9 0.5 1.0 1 0 0 1 1 1 1 Silicon transporter DUF3262 PF11660.3 EEB06878.1 - 0.021 14.9 1.4 0.026 14.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Jiraiya PF15038.1 EEB06878.1 - 0.034 13.5 0.2 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Jiraiya CcoS PF03597.10 EEB06878.1 - 3 7.3 5.7 1.1 8.8 0.7 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GET2 PF08690.5 EEB06879.1 - 0.0013 18.0 8.8 0.039 13.1 3.8 2.4 2 1 0 2 2 2 2 GET complex subunit GET2 Ste5 PF11610.3 EEB06879.1 - 0.028 13.9 0.4 0.084 12.4 0.2 1.8 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region Sulfate_transp PF00916.15 EEB06880.1 - 6e-46 156.6 8.0 1.2e-45 155.7 5.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEB06880.1 - 1.3e-23 82.4 1.7 1.3e-23 82.4 1.2 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEB06880.1 - 1.1e-21 76.4 0.0 3.6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EEB06880.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 STAS domain Pkinase PF00069.20 EEB06881.2 - 1.3e-33 116.3 0.0 4.2e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06881.2 - 1.9e-20 73.0 0.0 5.7e-14 51.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase FH2 PF02181.18 EEB06882.2 - 5.8e-65 219.5 0.7 1.3e-64 218.4 0.5 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EEB06882.2 - 6.3e-36 123.5 3.6 6.3e-36 123.5 2.5 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EEB06882.2 - 1.1e-08 34.7 1.1 4.6e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain ABC_tran PF00005.22 EEB06883.1 - 1e-19 71.1 0.0 3.8e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEB06883.1 - 1.9e-13 51.0 1.0 5.4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEB06883.1 - 9e-07 28.2 0.0 0.026 13.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEB06883.1 - 1.6e-05 24.3 0.3 3e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EEB06883.1 - 9.8e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EEB06883.1 - 0.00075 18.7 0.1 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEB06883.1 - 0.00081 19.7 0.1 0.0014 19.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB06883.1 - 0.0015 19.3 0.2 0.003 18.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEB06883.1 - 0.0027 16.8 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEB06883.1 - 0.0035 17.4 0.1 0.0073 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EEB06883.1 - 0.0044 16.4 0.1 0.0063 15.9 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EEB06883.1 - 0.0059 16.3 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EEB06883.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EEB06883.1 - 0.028 13.5 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EEB06883.1 - 0.031 13.7 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EEB06883.1 - 0.038 13.8 1.1 0.13 12.0 0.4 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EEB06883.1 - 0.043 14.0 0.2 0.14 12.3 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EEB06883.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EEB06883.1 - 0.074 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEB06883.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EEB06883.1 - 0.082 12.7 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Dynamin family Arf PF00025.16 EEB06883.1 - 0.087 12.0 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.1 EEB06883.1 - 0.094 12.6 0.9 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EEB06883.1 - 0.099 12.5 0.1 0.23 11.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 EEB06883.1 - 0.1 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EEB06883.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 EEB06883.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EEB06883.1 - 0.16 10.8 0.2 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF3584 PF12128.3 EEB06883.1 - 0.19 9.0 0.3 0.27 8.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAD PF12710.2 EEB06884.2 - 3e-20 73.2 0.0 6.8e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEB06884.2 - 1e-15 57.3 0.0 1.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEB06884.2 - 5.6e-14 53.0 0.1 2.9e-12 47.4 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB06884.2 - 1.5e-13 50.4 0.0 3.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEB06884.2 - 0.0026 17.3 0.5 0.0069 15.9 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ketoacyl-synt PF00109.21 EEB06885.1 - 1.9e-50 171.6 1.9 2.6e-50 171.2 1.3 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEB06885.1 - 3.1e-31 107.6 0.2 6.6e-31 106.6 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEB06885.1 - 0.00039 19.4 0.0 0.00065 18.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EEB06885.1 - 0.038 13.6 0.5 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Endonuclease_NS PF01223.18 EEB06887.1 - 9.7e-59 198.4 0.1 1.2e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-Tim10_DDP PF02953.10 EEB06888.1 - 7.5e-24 82.8 0.4 9.4e-24 82.4 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EEB06888.1 - 0.048 13.4 0.1 0.051 13.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) PMEI PF04043.10 EEB06888.1 - 0.065 13.1 0.2 0.076 12.9 0.1 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Alg6_Alg8 PF03155.10 EEB06889.1 - 2.7e-153 511.1 32.3 3.3e-153 510.9 22.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Bac_surface_Ag PF01103.18 EEB06890.1 - 1.3e-42 146.4 0.0 1.6e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Med27 PF11571.3 EEB06891.1 - 9.3e-08 32.0 2.6 2.3e-07 30.8 1.8 1.7 1 0 0 1 1 1 1 Mediator complex subunit 27 RolB_RolC PF02027.12 EEB06891.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family HA2 PF04408.18 EEB06892.1 - 1.8e-19 69.6 0.0 5.1e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEB06892.1 - 1.4e-11 44.0 0.0 5.3e-11 42.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB06892.1 - 5.1e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EEB06892.1 - 2.9e-05 23.8 0.0 9.3e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 EEB06892.1 - 0.0079 16.0 0.1 3 7.6 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEB06892.1 - 0.035 14.2 0.0 0.17 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EEB06892.1 - 0.08 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MIF4G PF02854.14 EEB06893.1 - 5e-58 195.9 0.2 9.6e-58 195.0 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EEB06893.1 - 7.5e-16 57.7 1.0 4.2e-15 55.3 0.7 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Fibrinogen_BP PF08017.6 EEB06893.1 - 1.4e-08 33.4 42.5 1.4e-08 33.4 29.4 1.6 2 0 0 2 2 2 1 Fibrinogen binding protein ACPS PF01648.15 EEB06894.2 - 3.5e-12 46.1 0.0 1.1e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily TPR_1 PF00515.23 EEB06895.1 - 1.1e-33 113.3 33.7 2.9e-07 29.7 0.1 10.9 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEB06895.1 - 3e-33 113.2 25.8 2.7e-10 39.7 0.4 7.5 4 2 4 9 9 9 7 TPR repeat TPR_2 PF07719.12 EEB06895.1 - 1.3e-32 109.0 30.2 2.5e-06 26.9 0.0 11.0 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06895.1 - 4.5e-24 82.3 17.1 1.1e-05 24.9 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EEB06895.1 - 1.3e-20 73.3 36.2 9e-14 51.3 2.3 6.1 3 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB06895.1 - 5.2e-20 71.1 21.0 1.2e-06 28.2 0.0 7.8 6 3 2 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06895.1 - 2e-19 69.6 7.7 1.3e-05 25.4 0.1 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEB06895.1 - 2e-17 61.8 6.8 0.028 14.6 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06895.1 - 5.2e-16 58.8 12.1 3.9e-05 24.1 0.0 7.1 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06895.1 - 2.2e-14 52.6 2.8 0.56 10.9 0.1 8.5 6 2 4 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEB06895.1 - 4.1e-09 36.2 17.6 0.062 13.7 0.1 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06895.1 - 4.3e-09 35.4 11.9 0.14 12.0 0.0 8.6 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB06895.1 - 1.6e-08 34.2 1.9 0.002 17.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 EEB06895.1 - 0.1 12.5 1.2 5.6 6.8 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EEB06895.1 - 0.2 11.5 5.5 3.2 7.7 0.0 3.9 3 2 1 4 4 3 0 MIT (microtubule interacting and transport) domain Acyltransferase PF01553.16 EEB06896.1 - 1.1e-28 99.3 0.1 1.5e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase Methyltransf_10 PF05971.7 EEB06897.2 - 2.4e-51 174.6 0.0 3.7e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) PrmA PF06325.8 EEB06897.2 - 0.048 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEB06897.2 - 0.079 12.3 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain N-glycanase_N PF09112.5 EEB06897.2 - 0.079 12.3 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Methyltransf_26 PF13659.1 EEB06897.2 - 0.15 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain But2 PF09792.4 EEB06898.1 - 1.2e-42 145.0 2.4 1.2e-42 145.0 1.7 2.5 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain TPT PF03151.11 EEB06899.1 - 8.3e-11 41.7 27.6 3.1e-08 33.3 10.5 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EEB06899.1 - 0.00013 22.0 34.6 0.00042 20.3 7.8 3.0 2 1 1 3 3 3 2 EamA-like transporter family Actin PF00022.14 EEB06901.1 - 2.1e-120 401.8 0.0 2.3e-120 401.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEB06901.1 - 1.3e-06 27.2 0.0 3.6e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein DUF3982 PF13138.1 EEB06902.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Asp PF00026.18 EEB06903.1 - 7.4e-59 199.5 12.8 8.9e-59 199.2 8.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEB06903.1 - 3.9e-07 30.1 1.3 3.9e-07 30.1 0.9 2.1 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEB06903.1 - 0.0034 17.8 2.9 1 9.9 0.3 3.5 3 1 0 3 3 3 2 Aspartyl protease His_Phos_2 PF00328.17 EEB06904.1 - 1e-49 169.7 0.0 1.2e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2765 PF10963.3 EEB06904.1 - 0.26 11.2 1.4 4.6 7.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2765) HhH-GPD PF00730.20 EEB06905.1 - 1.6e-17 63.7 0.0 1.9e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.1 EEB06905.1 - 0.0011 19.0 0.1 0.15 12.2 0.0 3.0 1 1 2 3 3 3 2 Helix-hairpin-helix domain ASL_C PF08328.6 EEB06905.1 - 0.0042 16.9 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Glyco_transf_34 PF05637.7 EEB06906.1 - 1.4e-73 247.3 0.1 1.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EEB06906.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase CRCB PF02537.10 EEB06907.1 - 5e-35 119.9 20.2 5.1e-24 84.4 2.0 2.7 3 0 0 3 3 3 2 CrcB-like protein Nuc_deoxyrib_tr PF05014.10 EEB06908.1 - 6.7e-29 100.0 0.0 8.5e-29 99.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase PA14_2 PF10528.4 EEB06909.1 - 7.3e-37 125.7 2.4 7.3e-37 125.7 1.7 2.5 2 0 0 2 2 2 1 GLEYA domain STE2 PF02116.10 EEB06910.1 - 2.5e-47 161.2 28.6 3e-47 161.0 19.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1771 PF08590.5 EEB06911.2 - 1.2e-18 66.9 10.4 2.2e-18 66.0 7.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEB06911.2 - 1.2e-16 60.6 0.1 2.6e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain Pterin_bind PF00809.17 EEB06911.2 - 0.043 13.1 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Pterin binding enzyme Peptidase_M17_N PF02789.12 EEB06911.2 - 0.1 12.3 0.1 0.34 10.6 0.0 1.9 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Vps23_core PF09454.5 EEB06912.1 - 4.3e-06 26.2 0.5 6.8e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Vps23 core domain MCPVI PF02993.9 EEB06912.1 - 0.61 10.1 7.4 1.4 9.0 5.1 1.5 1 0 0 1 1 1 0 Minor capsid protein VI PTR2 PF00854.16 EEB06914.1 - 8.5e-61 205.7 14.0 8.5e-61 205.7 9.7 1.4 2 0 0 2 2 2 1 POT family ADH_zinc_N PF00107.21 EEB06916.1 - 1.4e-31 108.7 0.1 2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEB06916.1 - 1.3e-15 57.0 0.1 1e-14 54.1 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEB06916.1 - 2.5e-15 57.5 0.0 5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EEB06916.1 - 0.0029 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EEB06916.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 EEB06916.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pescadillo_N PF06732.6 EEB06916.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Pescadillo N-terminus Amidase PF01425.16 EEB06917.1 - 2.6e-75 253.9 0.1 2.7e-73 247.3 0.1 2.1 2 0 0 2 2 2 2 Amidase RRM_1 PF00076.17 EEB06918.1 - 5.5e-09 35.5 0.0 1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06918.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06918.1 - 1.3e-05 24.9 0.2 2.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_GDSL_2 PF13472.1 EEB06919.1 - 1.8e-18 67.2 0.0 2.2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEB06919.1 - 1.2e-14 54.7 0.0 2.2e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Zip PF02535.17 EEB06920.1 - 2.7e-39 135.0 13.0 3.2e-39 134.8 9.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Lectin_leg-like PF03388.8 EEB06921.1 - 1.4e-68 230.5 0.0 1.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EEB06921.1 - 0.0019 17.6 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Asp_Glu_race_2 PF14669.1 EEB06921.1 - 0.063 12.5 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative aspartate racemase zf-RING_2 PF13639.1 EEB06922.1 - 3.8e-11 42.6 8.6 3.8e-11 42.6 6.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EEB06922.1 - 5.9e-10 39.1 1.6 5.9e-10 39.1 1.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 EEB06922.1 - 2.9e-09 36.4 6.8 2.9e-09 36.4 4.7 2.7 2 1 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.1 EEB06922.1 - 7.9e-06 25.4 6.1 7.9e-06 25.4 4.2 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB06922.1 - 3.5e-05 23.7 10.1 3.5e-05 23.7 7.0 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB06922.1 - 8.5e-05 22.2 6.3 8.5e-05 22.2 4.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEB06922.1 - 0.00056 19.5 9.4 0.00056 19.5 6.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEB06922.1 - 0.0032 17.2 0.9 0.0032 17.2 0.6 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.1 EEB06922.1 - 0.012 14.8 0.7 0.012 14.8 0.5 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.1 EEB06922.1 - 0.028 14.4 4.1 2.8 7.9 0.7 2.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EEB06922.1 - 0.53 10.0 5.4 1.9 8.2 3.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Cofilin_ADF PF00241.15 EEB06923.1 - 3.6e-26 91.5 0.6 6.2e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein AA_permease PF00324.16 EEB06924.1 - 1.1e-104 350.5 38.0 1.2e-104 350.3 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB06924.1 - 9.5e-27 93.5 41.6 1.7e-26 92.7 28.6 1.5 1 1 1 2 2 2 1 Amino acid permease Hydantoinase_B PF02538.9 EEB06925.1 - 8.9e-198 657.7 0.0 1.2e-197 657.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEB06925.1 - 2.8e-91 305.6 1.1 4.9e-91 304.8 0.3 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEB06925.1 - 2.8e-58 196.3 1.4 8.7e-57 191.4 0.0 2.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CHCH PF06747.8 EEB06926.2 - 4.3e-08 32.8 5.0 8.4e-08 31.9 3.5 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EEB06926.2 - 0.066 13.2 4.3 0.19 11.8 3.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EEB06926.2 - 0.069 12.9 4.0 0.39 10.5 2.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EEB06926.2 - 0.71 9.7 4.1 4.5 7.2 0.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EEB06926.2 - 1.3 9.1 6.1 5.8 7.0 0.3 2.6 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Amidohydro_1 PF01979.15 EEB06927.1 - 1.4e-46 159.7 0.0 1.9e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEB06927.1 - 6.7e-07 29.6 0.3 0.001 19.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EEB06927.1 - 4e-06 26.3 0.3 0.00044 19.5 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EEB06927.1 - 0.00018 21.2 0.0 0.00075 19.2 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase AA_permease PF00324.16 EEB06928.1 - 6.6e-118 394.0 46.0 7.6e-118 393.8 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB06928.1 - 5.5e-34 117.4 50.5 7.2e-34 117.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease PBP1_TM PF14812.1 EEB06929.2 - 0.029 14.6 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EIIBC-GUT_N PF03612.9 EEB06929.2 - 0.07 12.7 0.8 0.12 11.9 0.1 1.7 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3270 PF11674.3 EEB06929.2 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Pox_Ag35 PF03286.9 EEB06929.2 - 0.46 9.9 7.8 0.9 9.0 5.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Y_phosphatase PF00102.22 EEB06930.1 - 2.6e-62 210.2 0.1 3.8e-62 209.6 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EEB06930.1 - 1.2e-08 35.2 0.0 2.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 EEB06930.1 - 1.6e-06 28.2 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EEB06930.1 - 5.6e-05 22.7 0.0 0.00017 21.2 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEB06930.1 - 0.0043 17.3 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4511 PF14974.1 EEB06930.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) DUF543 PF04418.7 EEB06931.1 - 8.5e-29 99.3 0.0 9.8e-29 99.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Yippee-Mis18 PF03226.9 EEB06932.1 - 6.1e-14 51.8 0.4 7.3e-14 51.5 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EEB06932.1 - 0.0097 15.8 0.1 1.8 8.6 0.0 2.2 2 0 0 2 2 2 2 HNH endonuclease Endonuclease_7 PF02945.10 EEB06932.1 - 0.026 14.2 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Recombination endonuclease VII DUF2039 PF10217.4 EEB06932.1 - 0.14 12.2 2.3 0.31 11.0 0.5 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 EEB06932.1 - 0.62 9.9 2.9 3.4 7.6 0.2 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF2296 PF10058.4 EEB06932.1 - 0.66 9.7 4.0 13 5.5 0.0 2.8 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Sec7 PF01369.15 EEB06933.1 - 1.2e-38 132.7 0.9 2.4e-38 131.7 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EEB06933.1 - 1.7e-11 44.2 0.2 6.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EEB06933.1 - 8.7e-06 25.8 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pinin_SDK_memA PF04696.8 EEB06934.1 - 5.8e-11 42.1 23.1 5.8e-11 42.1 16.0 2.3 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region CAF-1_p150 PF11600.3 EEB06934.1 - 0.067 12.5 25.3 0.094 12.0 17.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDE_Tnp_1_3 PF13612.1 EEB06934.1 - 0.11 12.2 3.7 0.19 11.4 2.6 1.4 1 1 1 2 2 2 0 Transposase DDE domain Hex_IIIa PF02455.11 EEB06934.1 - 0.96 8.0 9.7 1.1 7.9 6.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Nha1_C PF08619.5 EEB06934.1 - 1.8 7.7 18.9 2.5 7.2 13.1 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PAT1 PF09770.4 EEB06934.1 - 2 6.5 21.7 2.3 6.3 15.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3535 PF12054.3 EEB06934.1 - 3 6.3 12.4 0.059 11.9 0.7 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3535) E1_dh PF00676.15 EEB06935.1 - 3.1e-115 384.0 0.3 4.8e-115 383.3 0.1 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEB06935.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EEB06935.1 - 0.23 12.1 4.2 4.6 7.9 0.1 2.9 2 1 0 2 2 2 0 KRTAP type 7 family ADH_zinc_N PF00107.21 EEB06936.1 - 2.6e-13 49.6 0.0 4.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEB06936.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EEB06936.1 - 0.053 13.4 0.0 0.49 10.2 0.0 2.2 1 1 0 2 2 2 0 short chain dehydrogenase His_Phos_1 PF00300.17 EEB06937.1 - 3e-41 141.1 0.0 3.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.16 EEB06938.1 - 2.3e-53 180.8 0.0 2.9e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.3 EEB06939.2 - 3.4e-18 65.5 15.0 1.4e-16 60.1 4.4 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2422 PF10337.4 EEB06939.2 - 1.1e-17 63.9 11.4 3.3e-09 36.0 0.2 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EEB06939.2 - 1.7e-13 50.5 17.5 1.7e-13 50.5 12.1 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EEB06939.2 - 1.6e-10 40.9 1.5 1e-08 35.1 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EEB06939.2 - 8.7e-10 37.6 9.7 8.7e-10 37.6 6.7 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF939 PF06081.6 EEB06939.2 - 9.2e-07 28.8 10.4 9.2e-07 28.8 7.2 3.0 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF939) Cyclin_C PF02984.14 EEB06939.2 - 0.073 12.9 1.8 0.25 11.2 0.1 2.7 3 0 0 3 3 3 0 Cyclin, C-terminal domain MVL PF12151.3 EEB06939.2 - 0.097 12.3 2.0 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Mannan-binding protein PBP1_TM PF14812.1 EEB06939.2 - 0.1 12.9 0.5 0.28 11.5 0.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ING PF12998.2 EEB06939.2 - 0.16 12.2 2.0 1 9.6 0.0 2.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding RabGAP-TBC PF00566.13 EEB06940.1 - 6.8e-45 153.1 0.0 1.9e-44 151.7 0.0 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TSC22 PF01166.13 EEB06940.1 - 0.033 14.1 4.8 0.039 13.9 0.8 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family Occludin_ELL PF07303.8 EEB06940.1 - 0.74 10.5 8.9 4.6 8.0 6.2 2.4 1 1 0 1 1 1 0 Occludin homology domain Z1 PF10593.4 EEB06940.1 - 1.3 8.1 7.5 2.6 7.1 1.1 3.3 2 2 1 3 3 3 0 Z1 domain Rab5-bind PF09311.6 EEB06940.1 - 3.5 7.4 21.6 0.11 12.4 9.9 2.2 3 0 0 3 3 3 0 Rabaptin-like protein DUF342 PF03961.8 EEB06940.1 - 5.2 5.3 7.1 8.6 4.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EEB06940.1 - 8.9 5.8 9.4 3 7.4 1.2 2.7 1 1 1 2 2 2 0 Septum formation initiator Y_phosphatase PF00102.22 EEB06941.2 - 6.3e-66 222.0 0.2 8.1e-66 221.7 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EEB06941.2 - 8.6e-07 29.2 0.0 0.00011 22.4 0.0 2.7 3 0 0 3 3 3 1 Rhodanese-like domain PTPlike_phytase PF14566.1 EEB06941.2 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EEB06941.2 - 0.0012 18.3 0.1 0.0032 17.0 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEB06941.2 - 0.0037 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF383 PF04063.9 EEB06942.2 - 4.2e-72 241.7 0.9 2.1e-70 236.2 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EEB06942.2 - 1.2e-22 79.2 1.9 1.2e-22 79.2 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT PF02985.17 EEB06942.2 - 0.024 14.7 0.5 0.54 10.4 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Type_III_YscX PF09474.5 EEB06942.2 - 0.05 13.6 0.7 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) HEAT_2 PF13646.1 EEB06942.2 - 0.079 13.2 0.1 2.2 8.6 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 EEB06942.2 - 0.13 12.8 1.0 37 4.9 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat tRNA-synt_1 PF00133.17 EEB06943.1 - 2.1e-42 144.9 0.0 1.9e-21 75.7 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEB06943.1 - 3.4e-20 72.0 0.0 7.6e-11 41.2 0.0 3.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEB06943.1 - 1e-14 54.5 0.5 2.3e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEB06943.1 - 3.1e-09 36.4 0.0 8.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pyr_redox_2 PF07992.9 EEB06944.1 - 1.2e-27 97.1 0.7 1.1e-26 94.0 0.5 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EEB06944.1 - 5.1e-13 48.4 0.0 1.5e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EEB06944.1 - 3.5e-12 46.5 1.6 1.4e-09 38.1 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB06944.1 - 5.2e-08 33.1 0.0 0.0018 18.3 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EEB06944.1 - 1e-06 28.3 0.0 5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 EEB06944.1 - 3.5e-06 27.1 0.0 9.8e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EEB06944.1 - 2.7e-05 23.9 0.0 0.59 9.8 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEB06944.1 - 0.00071 18.5 0.0 0.15 10.9 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EEB06944.1 - 0.0034 17.6 0.1 0.036 14.3 0.0 2.5 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EEB06944.1 - 0.035 12.9 0.5 1.7 7.3 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain EF1G PF00647.14 EEB06945.1 - 2.6e-40 136.4 0.0 4.4e-40 135.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EEB06945.1 - 1.2e-11 44.4 0.2 3.2e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB06945.1 - 2.4e-10 40.1 0.4 6.1e-10 38.8 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEB06945.1 - 1.2e-08 35.0 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEB06945.1 - 2.8e-07 30.6 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEB06945.1 - 1.2e-06 28.9 0.2 2.4e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.17 EEB06946.2 - 3.8e-18 64.8 0.0 6.8e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB06946.2 - 1.9e-12 46.9 0.0 3.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB06946.2 - 5.3e-10 39.0 0.0 8.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MS_channel PF00924.13 EEB06947.2 - 1e-27 96.8 5.4 3.4e-27 95.1 3.8 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel Ribosomal_S8e PF01201.17 EEB06948.1 - 1.2e-49 167.7 1.1 1.4e-49 167.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EEB06948.1 - 0.067 13.4 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Small acidic protein family Thioredoxin_7 PF13899.1 EEB06949.1 - 6e-17 61.4 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EEB06949.1 - 4.6e-15 55.4 0.0 1.5e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EEB06949.1 - 9.7e-14 50.6 0.8 1.9e-13 49.6 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain Thioredox_DsbH PF03190.10 EEB06949.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Phage_GP20 PF06810.6 EEB06949.1 - 0.044 13.2 0.6 0.074 12.4 0.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Thioredoxin_2 PF13098.1 EEB06949.1 - 0.13 12.4 0.0 0.72 10.0 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain UIM PF02809.15 EEB06949.1 - 0.13 11.9 0.2 0.13 11.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF2890 PF11081.3 EEB06949.1 - 0.17 11.9 1.2 0.33 10.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.1 EEB06949.1 - 0.24 11.7 2.0 0.75 10.1 0.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EEB06949.1 - 5.3 6.1 7.7 0.46 9.6 2.0 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Pkinase PF00069.20 EEB06950.1 - 1.8e-67 227.2 0.0 2.4e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06950.1 - 3.5e-45 154.1 0.0 4.9e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB06950.1 - 0.0046 15.9 2.3 0.014 14.4 0.0 2.6 3 1 0 3 3 3 1 Kinase-like ATP-synt_C PF00137.16 EEB06951.1 - 4.6e-26 90.5 26.0 4.8e-15 55.2 6.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C EMG1 PF03587.9 EEB06952.1 - 3.9e-78 261.4 0.0 5e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Utp11 PF03998.8 EEB06953.1 - 4.2e-69 233.0 31.6 4.8e-69 232.8 21.9 1.0 1 0 0 1 1 1 1 Utp11 protein HEAT_2 PF13646.1 EEB06954.2 - 2.7e-46 155.7 25.3 1.4e-08 34.8 0.0 14.9 13 3 0 14 14 14 6 HEAT repeats HEAT PF02985.17 EEB06954.2 - 6.3e-33 109.8 21.9 0.0012 18.7 0.0 20.1 21 0 0 21 21 21 8 HEAT repeat HEAT_EZ PF13513.1 EEB06954.2 - 6.6e-31 106.0 29.9 8.2e-06 26.1 0.0 18.5 12 5 6 20 20 20 7 HEAT-like repeat DUF3554 PF12074.3 EEB06954.2 - 4e-27 95.5 24.3 4.2e-26 92.1 7.6 5.3 4 1 1 5 5 5 2 Domain of unknown function (DUF3554) Cnd1 PF12717.2 EEB06954.2 - 3e-14 53.2 5.7 0.038 13.8 0.6 8.9 6 3 0 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEB06954.2 - 8.2e-13 48.5 0.0 0.66 10.3 0.0 8.4 7 1 1 8 8 8 3 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EEB06954.2 - 9e-07 28.7 7.8 0.95 9.4 0.1 6.9 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion Med15_fungi PF05397.7 EEB06954.2 - 0.0047 16.8 0.4 0.02 14.8 0.3 2.1 1 0 0 1 1 1 1 Mediator complex subunit 15 DUF937 PF06078.6 EEB06954.2 - 0.15 12.3 0.5 98 3.1 0.0 4.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF937) Arm PF00514.18 EEB06954.2 - 6 6.8 8.6 60 3.6 0.1 6.2 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Ric8 PF10165.4 EEB06955.1 - 2.1e-52 178.4 0.0 2.9e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Mitofilin PF09731.4 EEB06956.1 - 1.7e-52 178.8 29.8 1e-41 143.3 19.2 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein MFS_1 PF07690.11 EEB06957.1 - 9.3e-42 142.9 33.9 9.3e-42 142.9 23.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB06957.1 - 1.8e-13 49.9 29.4 8e-12 44.4 5.5 2.6 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EEB06957.1 - 1.1e-12 46.9 9.8 1.1e-12 46.9 6.8 1.6 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HlyIII PF03006.15 EEB06957.1 - 0.01 15.2 1.4 0.01 15.2 1.0 3.2 1 1 2 3 3 3 0 Haemolysin-III related DUF2781 PF10914.3 EEB06957.1 - 0.048 13.4 1.1 2 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) Polysacc_synt_4 PF04669.8 EEB06958.1 - 5.3e-24 84.6 1.3 4.2e-23 81.6 0.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Prp18 PF02840.10 EEB06958.1 - 0.048 13.4 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Prp18 domain XPG_N PF00752.12 EEB06959.1 - 8.4e-38 128.7 0.0 2.6e-37 127.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEB06959.1 - 2e-23 82.2 0.0 7.8e-23 80.3 0.0 2.1 1 0 0 1 1 1 1 XPG I-region Sad1_UNC PF07738.8 EEB06960.1 - 7.7e-35 119.6 0.0 1.7e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_M24 PF00557.19 EEB06961.2 - 4.7e-47 160.2 0.0 5.9e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEB06961.2 - 0.0004 20.2 8.7 0.0004 20.2 6.1 1.9 2 0 0 2 2 2 1 MYND finger DnaJ-X PF14308.1 EEB06962.2 - 5.8e-63 211.8 5.6 5.8e-63 211.8 3.9 2.0 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EEB06962.2 - 4.6e-27 93.5 2.2 1.7e-26 91.7 1.5 2.0 1 0 0 1 1 1 1 DnaJ domain Dynactin_p62 PF05502.8 EEB06962.2 - 2.1 7.0 4.8 6.6 5.3 3.3 1.8 1 1 0 1 1 1 0 Dynactin p62 family CHZ PF09649.5 EEB06963.1 - 1.6e-10 40.0 0.3 1.6e-10 40.0 0.2 1.9 2 0 0 2 2 2 1 Histone chaperone domain CHZ PUF PF00806.14 EEB06964.1 - 1.5e-36 121.8 6.9 7.7e-08 31.4 0.0 8.0 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Condensin2nSMC PF12422.3 EEB06964.1 - 0.036 13.7 1.2 0.1 12.3 0.1 2.4 2 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Phage_int_SAM_4 PF13495.1 EEB06964.1 - 0.087 13.1 0.4 0.97 9.7 0.0 2.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CTD_bind PF04818.8 EEB06965.1 - 0.00051 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EEB06965.1 - 0.0059 16.7 8.7 0.035 14.2 6.0 2.3 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-RING_2 PF13639.1 EEB06965.1 - 0.056 13.2 0.5 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Ring finger domain ADK PF00406.17 EEB06966.1 - 2.4e-62 209.2 0.0 2.9e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EEB06966.1 - 2.8e-15 55.6 0.0 5.8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EEB06966.1 - 2.4e-07 31.5 0.0 3.7e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB06966.1 - 4.1e-07 29.9 0.0 2.2e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEB06966.1 - 8.8e-05 21.6 0.1 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EEB06966.1 - 0.00038 20.7 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNase_HII PF01351.13 EEB06967.1 - 1.7e-58 197.5 0.0 2.2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII CAP_GLY PF01302.20 EEB06968.1 - 6.6e-26 89.8 0.7 1.1e-25 89.0 0.2 1.6 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EEB06968.1 - 5.9e-19 68.1 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEB06968.1 - 3.7e-07 29.4 0.1 8.5e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family BTB PF00651.26 EEB06969.1 - 1.5e-18 66.8 2.1 2.1e-09 37.3 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EEB06969.1 - 1.1e-08 34.4 0.2 1.9e-07 30.5 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EEB06969.1 - 1.4e-07 31.5 0.0 5e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB06969.1 - 4.8e-07 30.0 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEB06969.1 - 3.1e-06 27.5 0.0 1.7e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB06969.1 - 0.00027 20.9 0.1 0.0072 16.4 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_11 PF08241.7 EEB06970.2 - 6.5e-12 45.7 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB06970.2 - 9.7e-07 28.6 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB06970.2 - 0.0004 20.8 0.1 0.0033 17.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB06970.2 - 0.00046 19.8 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB06970.2 - 0.0018 18.6 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB06970.2 - 0.0096 16.4 0.1 0.044 14.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB06970.2 - 0.022 14.7 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCHC PF00098.18 EEB06971.2 - 1.9e-40 134.8 47.8 5e-07 29.3 0.5 6.5 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 EEB06971.2 - 3.2e-13 49.1 35.4 0.0066 16.0 0.3 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 EEB06971.2 - 3e-08 33.2 40.8 0.013 15.2 0.2 6.1 1 1 5 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EEB06971.2 - 0.00032 20.1 0.8 0.00032 20.1 0.5 6.0 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EEB06971.2 - 0.014 15.0 1.3 0.014 15.0 0.9 5.6 5 1 1 6 6 6 0 Zinc knuckle F-box-like_2 PF13013.1 EEB06972.1 - 1.4e-33 114.8 0.2 1.4e-33 114.8 0.2 2.2 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 EEB06972.1 - 0.00067 19.3 0.3 0.0017 18.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like EB1 PF03271.12 EEB06973.1 - 1.3e-16 60.2 0.3 3.7e-16 58.8 0.2 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EEB06973.1 - 8.5e-06 25.7 0.6 1.8e-05 24.7 0.4 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DMAP_binding PF06464.6 EEB06973.1 - 0.034 14.7 0.2 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 DMAP1-binding Domain Ribosomal_S7e PF01251.13 EEB06974.1 - 5.2e-84 280.4 2.1 5.9e-84 280.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TENA_THI-4 PF03070.11 EEB06975.1 - 6.1e-10 39.1 0.1 2.2e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Fungal_trans PF04082.13 EEB06976.1 - 3.6e-26 91.5 0.9 3.6e-26 91.5 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB06976.1 - 5.1e-11 42.2 15.0 1.2e-10 41.1 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KIP1 PF07765.7 EEB06976.1 - 0.57 10.0 3.4 3.2 7.6 0.2 2.9 3 0 0 3 3 3 0 KIP1-like protein CIMR PF00878.13 EEB06977.1 - 1.4e-10 41.0 0.5 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EEB06977.1 - 2.2e-10 39.9 0.3 3e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EEB06977.1 - 3.6e-05 23.1 0.2 0.00018 20.8 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 COX14 PF14880.1 EEB06977.1 - 2 8.1 3.7 4.4 6.9 2.5 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Mito_carr PF00153.22 EEB06978.1 - 1.6e-65 216.8 4.4 6.6e-24 83.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EEB06979.1 - 8.4e-22 77.2 2.6 8.4e-22 77.2 1.8 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB06979.1 - 1.8e-08 34.1 11.6 3.3e-08 33.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF413 PF04219.7 EEB06980.2 - 0.0059 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF Palm_thioest PF02089.10 EEB06981.1 - 3.5e-41 140.9 0.0 5.2e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PAP2 PF01569.16 EEB06981.1 - 2.3e-09 37.0 4.3 2.3e-09 37.0 3.0 1.7 1 1 0 1 1 1 1 PAP2 superfamily Cyclin_N PF00134.18 EEB06982.1 - 1.2e-19 70.0 2.4 6e-12 45.2 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EEB06982.1 - 0.037 13.8 1.5 0.59 9.9 0.1 2.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat GVQW PF13900.1 EEB06982.1 - 0.054 13.4 0.5 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Putative binding domain Cyclin_C PF02984.14 EEB06982.1 - 0.064 13.1 4.0 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Cyclin, C-terminal domain Pkinase PF00069.20 EEB06983.1 - 3.9e-43 147.4 0.5 6.2e-23 81.2 0.3 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB06983.1 - 1.4e-15 57.1 0.1 6.3e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEB06983.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EEB06984.1 - 1.4e-42 145.6 32.7 1.4e-42 145.6 22.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EEB06984.1 - 1.8 8.1 6.5 0.43 10.1 0.2 2.8 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.11 EEB06985.2 - 7.4e-31 107.1 37.7 7.4e-31 107.1 26.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB06985.2 - 4.4e-11 42.0 9.8 4.4e-11 42.0 6.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter RseC_MucC PF04246.7 EEB06985.2 - 0.076 12.5 3.0 0.23 11.0 0.0 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PAP2 PF01569.16 EEB06985.2 - 6.3 6.4 16.1 0.31 10.7 2.2 3.5 1 1 1 2 2 2 0 PAP2 superfamily Helicase_C PF00271.26 EEB06986.1 - 3.1e-16 58.9 0.9 1.1e-15 57.2 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEB06986.1 - 1.2e-12 47.6 0.1 4.2e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEB06986.1 - 1.6e-11 43.9 0.0 5.2e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB06986.1 - 1.3e-06 28.6 0.0 6.3e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEB06986.1 - 0.0086 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 EEB06986.1 - 0.011 15.4 0.0 0.035 13.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EEB06986.1 - 0.025 14.8 0.2 0.18 12.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter KaiC PF06745.8 EEB06986.1 - 0.049 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EEB06986.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AA_permease_2 PF13520.1 EEB06987.1 - 4.7e-60 203.3 52.3 5.7e-60 203.0 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB06987.1 - 2.2e-15 55.9 45.3 2.9e-15 55.5 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease GDI PF00996.13 EEB06988.1 - 4e-46 157.2 0.1 5e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor ABC1 PF03109.11 EEB06989.2 - 2.2e-36 124.4 0.0 4e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EEB06989.2 - 0.0064 15.8 0.0 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family TPR_11 PF13414.1 EEB06990.1 - 1.1e-06 28.2 2.4 1.3e-05 24.7 1.3 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEB06990.1 - 0.00016 21.3 7.8 0.00024 20.7 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEB06990.1 - 0.00027 20.4 4.3 0.0026 17.4 0.2 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB06990.1 - 0.00039 20.8 1.5 0.14 12.9 0.1 3.6 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB06990.1 - 0.0015 18.0 0.3 0.0015 18.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB06990.1 - 0.0032 17.7 4.5 0.033 14.5 0.2 3.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEB06990.1 - 0.0095 15.0 0.2 0.42 9.6 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB06990.1 - 0.017 15.7 2.3 5.8 7.7 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEB06990.1 - 0.027 14.4 3.3 0.13 12.2 2.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEB06990.1 - 0.04 13.7 3.7 0.074 12.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 EEB06991.1 - 1.2e-16 59.8 8.3 9.3e-05 22.1 0.2 6.7 8 0 0 8 8 8 3 WD domain, G-beta repeat Bot1p PF12298.3 EEB06992.1 - 2.5e-46 157.7 0.8 3.4e-46 157.3 0.2 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HTH_23 PF13384.1 EEB06992.1 - 0.00069 19.1 0.0 0.43 10.2 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.1 EEB06992.1 - 0.0096 15.9 0.1 0.03 14.3 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Mor PF08765.6 EEB06992.1 - 0.018 14.8 0.1 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 Mor transcription activator family Abhydro_lipase PF04083.11 EEB06993.2 - 1.7e-22 78.5 0.0 3.5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEB06993.2 - 5.9e-16 58.7 0.1 8.8e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEB06993.2 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB06993.2 - 3.5e-08 33.3 0.0 3.7e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEB06993.2 - 4.8e-05 22.9 0.0 0.0086 15.5 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EEB06993.2 - 0.00012 21.6 0.0 0.054 12.9 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EEB06993.2 - 0.0012 18.0 0.0 0.13 11.4 0.0 2.6 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EEB06993.2 - 0.098 12.0 0.1 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Lipase_2 PF01674.13 EEB06993.2 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) DNA_pol_phi PF04931.8 EEB06994.1 - 1e-149 499.8 24.9 1.5e-149 499.2 17.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi SpaB_C PF14028.1 EEB06994.1 - 0.055 13.0 0.2 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 SpaB C-terminal domain SRR1 PF07985.7 EEB06995.1 - 3.6e-14 52.4 0.0 6.9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 UDPG_MGDP_dh_C PF03720.10 EEB06995.1 - 0.057 13.5 0.0 0.59 10.3 0.0 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain RNA_pol_Rpb8 PF03870.10 EEB06996.1 - 1.3e-39 135.5 3.9 1.4e-38 132.1 2.7 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_L28 PF00830.14 EEB06997.2 - 5.1e-16 58.2 0.1 8.9e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28 family UPF0029 PF01205.14 EEB06998.1 - 5.2e-18 64.7 0.4 2.1e-17 62.8 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 YmgB PF10798.3 EEB06998.1 - 0.08 12.7 0.2 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR LUC7 PF03194.10 EEB06998.1 - 0.27 10.7 5.5 0.63 9.5 3.8 1.5 1 0 0 1 1 1 0 LUC7 N_terminus Presenilin PF01080.12 EEB06998.1 - 3.4 6.3 10.3 5.7 5.6 7.2 1.4 1 0 0 1 1 1 0 Presenilin SMAP PF15477.1 EEB06999.1 - 8.7e-13 48.3 0.4 8.7e-13 48.3 0.3 3.0 2 1 0 2 2 2 1 Small acidic protein family DUF1777 PF08648.7 EEB06999.1 - 0.00015 21.5 9.7 0.00019 21.2 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF3527 PF12043.3 EEB06999.1 - 0.26 10.8 10.8 0.29 10.6 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Cep57_CLD PF14073.1 EEB06999.1 - 0.54 10.0 11.6 0.54 10.0 7.3 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 FliD_N PF02465.13 EEB06999.1 - 2.2 8.6 9.8 3.2 8.1 6.5 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Neur_chan_memb PF02932.11 EEB06999.1 - 7.2 6.4 7.1 8.1 6.2 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_16 PF13191.1 EEB07000.2 - 2.6e-13 50.3 0.0 7.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB07000.2 - 3.2e-13 49.9 0.0 9.4e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEB07000.2 - 1.2e-12 48.1 0.0 5.9e-12 45.9 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EEB07000.2 - 1.3e-07 31.2 0.2 3.7e-07 29.7 0.0 1.9 2 0 0 2 2 1 1 CDC6, C terminal AAA_19 PF13245.1 EEB07000.2 - 0.00018 21.1 0.0 0.00061 19.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EEB07000.2 - 0.00043 20.0 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EEB07000.2 - 0.00047 19.2 0.0 0.0009 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EEB07000.2 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 EEB07000.2 - 0.0012 18.4 0.2 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EEB07000.2 - 0.003 16.5 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain PIF1 PF05970.9 EEB07000.2 - 0.003 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EEB07000.2 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EEB07000.2 - 0.0061 15.8 0.4 0.016 14.5 0.3 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain NB-ARC PF00931.17 EEB07000.2 - 0.0077 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.13 EEB07000.2 - 0.011 15.3 2.4 0.17 11.3 0.0 3.2 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EEB07000.2 - 0.012 15.2 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 Helicase Sigma54_activat PF00158.21 EEB07000.2 - 0.018 14.5 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 EEB07000.2 - 0.02 13.8 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 EEB07000.2 - 0.038 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4414 PF14377.1 EEB07000.2 - 0.079 12.8 0.1 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) AAA_17 PF13207.1 EEB07000.2 - 0.1 13.4 0.0 0.21 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EEB07000.2 - 0.1 11.2 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EEB07001.1 - 9.7e-23 79.1 11.9 5e-09 35.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEB07001.1 - 0.0045 16.4 0.0 9.8 5.7 0.0 4.4 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.16 EEB07001.1 - 0.018 13.6 2.2 1.1 7.7 0.6 3.3 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 EEB07001.1 - 0.03 12.1 0.0 0.046 11.5 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Rax2 PF12768.2 EEB07001.1 - 0.034 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gmad1 PF10647.4 EEB07001.1 - 0.045 13.1 0.8 0.84 8.9 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 EEB07001.1 - 0.071 12.8 0.4 1.9 8.1 0.0 2.3 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Glyco_hydro_15 PF00723.16 EEB07002.2 - 2.2e-67 227.5 0.0 2.8e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Tim44 PF04280.10 EEB07003.1 - 5.6e-31 107.4 0.1 8.6e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 Tim44-like domain CwfJ_C_1 PF04677.10 EEB07004.2 - 2.6e-38 130.4 1.0 8.8e-38 128.7 0.2 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEB07004.2 - 2.1e-19 69.8 0.1 5.6e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rad52_Rad22 PF04098.10 EEB07005.2 - 8e-59 197.7 0.0 1.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HlyIII PF03006.15 EEB07006.1 - 6.8e-53 179.3 24.9 8.6e-53 179.0 17.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related P4Ha_N PF08336.6 EEB07006.1 - 0.11 12.3 0.1 5.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ribosomal_L38e PF01781.13 EEB07007.1 - 2.5e-34 116.8 1.5 2.8e-34 116.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family UQ_con PF00179.21 EEB07008.1 - 2.6e-48 163.0 0.0 2.9e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEB07008.1 - 0.003 17.2 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEB07008.1 - 0.089 12.6 1.9 0.13 12.2 1.3 1.7 1 1 0 1 1 1 0 RWD domain KH_3 PF13014.1 EEB07009.2 - 1.3e-06 27.8 0.3 0.00029 20.4 0.1 2.7 2 0 0 2 2 2 2 KH domain KH_1 PF00013.24 EEB07009.2 - 2.5e-06 27.0 0.0 9.4e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 KH domain DUF1777 PF08648.7 EEB07009.2 - 0.01 15.5 28.7 0.01 15.5 19.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) ThiF PF00899.16 EEB07010.1 - 1.7e-35 121.7 0.2 3.3e-35 120.8 0.1 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EEB07010.1 - 0.00064 18.7 0.8 0.0019 17.2 0.5 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 EEB07010.1 - 0.037 13.0 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 ApbA PF02558.11 EEB07010.1 - 0.037 13.4 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EEB07010.1 - 0.092 11.6 0.4 0.2 10.5 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EEB07010.1 - 0.17 11.8 0.6 0.85 9.6 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain TRAM_LAG1_CLN8 PF03798.11 EEB07011.1 - 2.9e-33 115.1 29.1 2.9e-33 115.1 20.2 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EEB07011.1 - 2.4e-15 55.7 0.6 2.4e-15 55.7 0.4 2.4 3 0 0 3 3 3 1 TRAM1-like protein InaF-motif PF15018.1 EEB07014.1 - 0.024 14.0 0.1 0.084 12.3 0.0 1.9 1 0 0 1 1 1 0 TRP-interacting helix DUF3336 PF11815.3 EEB07015.1 - 3e-36 124.0 6.3 6.5e-36 123.0 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEB07015.1 - 2.7e-21 76.4 0.0 6.2e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase PLA2_B PF01735.13 EEB07016.1 - 7.7e-175 581.7 1.4 9.1e-175 581.5 1.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EEB07017.1 - 3.9e-203 675.0 7.1 4.7e-203 674.8 4.9 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.16 EEB07017.1 - 0.26 11.1 3.1 0.5 10.2 2.2 1.4 1 0 0 1 1 1 0 IBR domain Cytochrom_D1 PF02239.11 EEB07018.1 - 2.6e-05 22.7 1.3 0.00049 18.5 0.2 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EEB07018.1 - 0.0037 17.4 9.0 0.094 13.0 0.2 4.6 5 0 0 5 5 5 2 PQQ-like domain WD40 PF00400.27 EEB07018.1 - 0.083 12.8 0.1 0.083 12.8 0.0 5.2 5 1 1 6 6 6 0 WD domain, G-beta repeat Nop14 PF04147.7 EEB07018.1 - 0.12 10.2 7.8 0.16 9.8 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EEB07018.1 - 1.7 7.6 15.1 2.6 7.0 10.5 1.2 1 0 0 1 1 1 0 BUD22 zf-C2HC5 PF06221.8 EEB07019.1 - 3e-22 78.1 5.8 5e-22 77.4 4.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type RD3 PF14473.1 EEB07019.1 - 0.0017 17.8 4.7 0.064 12.7 0.3 2.6 2 0 0 2 2 2 2 RD3 protein PWI PF01480.12 EEB07019.1 - 0.029 14.4 0.1 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 PWI domain DOG1 PF14144.1 EEB07019.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Seed dormancy control YebO PF13974.1 EEB07019.1 - 0.37 10.6 7.7 0.3 10.8 0.3 3.0 2 0 0 2 2 2 0 YebO-like protein CTD PF12815.2 EEB07020.1 - 4.8e-46 156.1 78.6 4.1e-23 82.1 18.4 3.3 1 1 3 4 4 4 4 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EEB07020.1 - 4.9e-28 96.6 0.0 1e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EEB07020.1 - 3.1e-20 71.0 10.0 2.1e-08 33.5 0.9 5.5 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.3 EEB07020.1 - 5.9e-16 58.8 12.7 5.9e-16 58.8 8.8 3.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal MS_channel PF00924.13 EEB07020.1 - 0.083 12.2 0.4 0.29 10.4 0.0 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel BRCT PF00533.21 EEB07021.1 - 2.4e-40 136.5 2.9 1.9e-12 47.1 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB07021.1 - 7.7e-39 131.3 0.1 1.4e-17 63.2 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain Nol1_Nop2_Fmu PF01189.12 EEB07022.2 - 6.7e-32 110.9 0.0 5.9e-17 61.9 0.0 3.4 1 1 2 3 3 3 3 NOL1/NOP2/sun family Lipase_3 PF01764.20 EEB07023.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RNA_pol_Rpb5_C PF01191.14 EEB07024.1 - 2.6e-34 116.6 1.5 2.8e-34 116.5 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEB07024.1 - 1.7e-27 95.6 0.0 2.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEB07024.1 - 0.0073 16.1 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease DUF4480 PF13715.1 EEB07024.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Glyco_trans_1_4 PF13692.1 EEB07025.1 - 1.5e-21 76.9 0.0 6.9e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEB07025.1 - 1.6e-09 37.3 0.0 3.8e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEB07025.1 - 2.2e-06 27.8 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEB07025.1 - 0.00028 21.0 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain SNARE PF05739.14 EEB07026.1 - 2.2e-08 33.6 0.4 2.8e-08 33.3 0.3 1.2 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.7 EEB07026.1 - 0.0067 16.2 0.1 0.0087 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Sec20 PF03908.8 EEB07026.1 - 0.01 15.5 0.2 0.015 14.9 0.1 1.3 1 0 0 1 1 1 0 Sec20 Syntaxin_2 PF14523.1 EEB07026.1 - 0.036 14.0 0.2 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Use1 PF09753.4 EEB07026.1 - 0.061 12.7 0.5 0.076 12.4 0.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Dynamitin PF04912.9 EEB07026.1 - 0.17 10.6 0.7 0.22 10.3 0.5 1.1 1 0 0 1 1 1 0 Dynamitin Pkinase PF00069.20 EEB07027.1 - 4e-39 134.3 0.0 5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07027.1 - 1.1e-13 50.8 0.0 1.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB07027.1 - 0.00016 21.5 0.0 0.0011 18.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB07027.1 - 0.0027 16.7 0.0 0.0051 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EEB07027.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EEB07027.1 - 0.062 12.0 0.1 0.084 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ATP-synt_J PF04911.7 EEB07028.1 - 1.4e-19 69.2 0.1 1.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain DJ-1_PfpI PF01965.19 EEB07029.1 - 5.4e-24 84.3 0.0 6.9e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEB07029.1 - 1.9e-08 33.7 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase SNO PF01174.14 EEB07029.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Enolase_C PF00113.17 EEB07030.1 - 4e-148 492.1 0.0 5.7e-148 491.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEB07030.1 - 4e-58 195.0 0.6 6.9e-58 194.2 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EEB07030.1 - 4.7e-05 23.3 0.1 0.00041 20.2 0.0 2.3 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EEB07030.1 - 0.0071 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EEB07030.1 - 0.008 16.6 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain EVI2A PF05399.6 EEB07031.1 - 0.1 11.8 1.4 0.15 11.3 1.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) AA_permease_2 PF13520.1 EEB07034.2 - 6.3e-55 186.4 56.0 7.6e-55 186.1 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07034.2 - 1.9e-21 75.9 46.8 2.6e-21 75.5 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.8 EEB07035.1 - 2.3e-17 63.2 0.7 2.3e-17 63.2 0.5 1.3 2 0 0 2 2 2 1 RTA1 like protein CUE PF02845.11 EEB07036.1 - 2.7e-10 39.5 0.1 4.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain TFR_dimer PF04253.10 EEB07037.1 - 1.3e-18 66.7 0.0 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EEB07037.1 - 1.3e-07 31.2 0.0 3.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.12 EEB07037.1 - 7.9e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF1212 PF06738.7 EEB07038.1 - 1.4e-39 135.5 7.3 6.5e-37 126.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEB07038.1 - 6.5e-22 77.8 8.2 6.5e-22 77.8 5.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) AzlD PF05437.7 EEB07038.1 - 0.036 13.9 2.9 0.1 12.5 2.0 1.8 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DNMT1-RFD PF12047.3 EEB07039.1 - 4.1e-13 49.2 0.1 8.6e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF2815 PF10991.3 EEB07039.1 - 0.0051 16.3 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2815) SURF4 PF02077.10 EEB07040.1 - 1.9e-104 348.7 7.1 2.2e-104 348.5 4.9 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.6 EEB07040.1 - 0.02 14.7 1.2 0.02 14.7 0.8 3.2 2 2 0 3 3 3 0 HR-like lesion-inducing DUF1212 PF06738.7 EEB07040.1 - 1.8 8.0 9.2 0.21 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Ribosomal_L36e PF01158.13 EEB07041.1 - 4.3e-39 132.4 3.3 4.8e-39 132.2 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.1 EEB07041.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal PBS_linker_poly PF00427.16 EEB07041.1 - 0.096 12.3 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide cobW PF02492.14 EEB07044.2 - 2.1e-47 160.8 2.6 2.1e-47 160.8 1.8 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEB07044.2 - 4e-19 68.1 0.1 2e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain T2SE PF00437.15 EEB07044.2 - 0.00075 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEB07044.2 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EEB07044.2 - 0.018 15.0 0.1 0.053 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain CDC45 PF02724.9 EEB07044.2 - 0.021 12.8 0.2 0.029 12.4 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.1 EEB07044.2 - 0.023 14.8 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEB07044.2 - 0.028 14.0 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EEB07044.2 - 0.031 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EEB07044.2 - 0.039 14.2 0.6 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2793 PF10983.3 EEB07044.2 - 0.063 13.0 0.6 0.18 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) UPF0079 PF02367.12 EEB07044.2 - 0.092 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EEB07044.2 - 0.095 12.9 0.4 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EEB07044.2 - 0.12 12.2 0.3 0.39 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain SSF PF00474.12 EEB07045.1 - 1.4e-17 63.4 24.7 2.9e-17 62.4 17.1 1.6 1 0 0 1 1 1 1 Sodium:solute symporter family MRAP PF15183.1 EEB07045.1 - 0.099 12.2 2.7 2.6 7.7 0.0 3.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF2613 PF11021.3 EEB07045.1 - 7.8 6.2 8.4 7.9 6.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) Transferase PF02458.10 EEB07046.1 - 4.6e-26 91.2 0.0 5.1e-25 87.7 0.0 1.9 2 0 0 2 2 2 2 Transferase family Transferase PF02458.10 EEB07047.2 - 2.4e-25 88.8 0.0 6.6e-24 84.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family Glyco_hydro_31 PF01055.21 EEB07051.2 - 3.9e-156 520.3 9.1 5.5e-156 519.8 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEB07051.2 - 0.00053 19.7 0.2 0.0032 17.3 0.2 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like Exonuc_VII_S PF02609.11 EEB07051.2 - 0.26 11.0 0.1 0.69 9.7 0.0 1.7 2 0 0 2 2 2 0 Exonuclease VII small subunit RTA1 PF04479.8 EEB07052.2 - 9.1e-44 149.6 5.1 9.1e-44 149.6 3.5 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF2839 PF10999.3 EEB07052.2 - 0.065 13.2 0.2 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF202 PF02656.10 EEB07052.2 - 0.2 11.8 4.4 13 6.0 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) AA_permease_2 PF13520.1 EEB07053.1 - 5.5e-49 166.8 51.4 6.9e-49 166.5 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07053.1 - 1.5e-18 66.3 43.3 2.3e-18 65.8 30.0 1.2 1 0 0 1 1 1 1 Amino acid permease Gp_dh_C PF02800.15 EEB07055.1 - 1.2e-74 248.9 0.1 1.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEB07055.1 - 1.3e-61 207.0 0.1 2.6e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EEB07055.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EEB07055.1 - 0.024 14.5 1.8 0.079 12.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EEB07055.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.13 EEB07058.1 - 4e-05 23.4 14.8 7.2e-05 22.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEB07059.1 - 1.4e-39 135.8 33.9 1.6e-37 129.0 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EEB07059.1 - 0.0078 16.2 2.4 0.0078 16.2 1.6 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) OSTbeta PF15048.1 EEB07059.1 - 0.045 13.8 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein SLAC1 PF03595.12 EEB07060.1 - 2e-68 230.4 41.4 2.3e-68 230.2 28.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FMN_dh PF01070.13 EEB07061.1 - 3e-123 411.2 0.0 3.6e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EEB07061.1 - 1.3e-05 24.4 0.0 0.043 12.8 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EEB07061.1 - 3.3e-05 23.1 0.4 5.9e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEB07061.1 - 0.00041 19.3 0.5 0.0072 15.2 0.2 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EEB07061.1 - 0.0051 15.7 0.1 0.0077 15.1 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EEB07061.1 - 0.0078 15.5 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EEB07061.1 - 0.072 12.1 0.1 0.14 11.1 0.0 1.4 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Acetyltransf_CG PF14542.1 EEB07062.2 - 0.042 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CBM_3 PF00942.13 EEB07062.2 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Cellulose binding domain AA_permease_2 PF13520.1 EEB07063.1 - 1e-35 123.1 40.2 1.3e-35 122.8 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07063.1 - 2.9e-20 72.0 36.5 4.1e-20 71.5 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease GFA PF04828.9 EEB07064.1 - 3.9e-12 45.9 0.6 6.6e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EEB07064.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EEB07064.1 - 0.12 12.1 2.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Double zinc ribbon adh_short PF00106.20 EEB07065.1 - 1.3e-25 90.2 0.0 2.4e-25 89.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB07065.1 - 1.7e-15 57.4 0.0 2.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB07065.1 - 4e-08 33.1 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEB07065.1 - 4.8e-08 32.7 0.0 7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB07065.1 - 5.4e-06 26.5 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEB07065.1 - 1.7e-05 23.8 0.0 5e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain EFhand_Ca_insen PF08726.5 EEB07065.1 - 0.056 13.4 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand NmrA PF05368.8 EEB07065.1 - 0.063 12.5 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EEB07066.1 - 9.2e-40 136.1 0.0 3.6e-39 134.2 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EEB07066.1 - 2.7e-29 101.7 0.0 4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEB07066.1 - 1.3e-14 54.1 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB07066.1 - 6.2e-09 36.1 0.0 3.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEB07066.1 - 2.7e-06 26.3 0.1 1e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEB07066.1 - 2.8e-06 27.3 0.1 6.1e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EEB07066.1 - 0.00011 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EEB07066.1 - 0.00066 18.6 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEB07066.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EEB07066.1 - 0.0049 15.7 0.0 0.01 14.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Transp_cyt_pur PF02133.10 EEB07067.2 - 3.5e-149 497.1 44.0 4.2e-149 496.8 30.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin G6PD_C PF02781.11 EEB07068.1 - 2.5e-80 269.4 0.0 3.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEB07068.1 - 1.5e-42 145.9 0.0 2.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_S10 PF00338.17 EEB07068.1 - 0.023 14.5 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e GFO_IDH_MocA PF01408.17 EEB07068.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 EEB07069.2 - 9.4e-30 103.3 2.2 1.4e-29 102.7 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB07069.2 - 3.5e-09 36.4 11.1 6.5e-09 35.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EEB07070.1 - 2.2e-131 438.5 40.7 2.7e-131 438.2 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB07070.1 - 1.1e-33 116.4 44.8 1.3e-33 116.2 31.1 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EEB07071.1 - 2.2e-22 78.9 0.0 3.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB07071.1 - 0.00032 21.5 0.0 0.00067 20.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 EEB07072.1 - 2.1e-29 102.3 35.3 2.1e-29 102.3 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB07072.1 - 1.9e-12 46.5 15.2 1.9e-12 46.5 10.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.15 EEB07072.1 - 1.4 8.2 14.3 0.17 11.1 2.7 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF21 SSI PF00720.12 EEB07073.1 - 0.056 13.3 0.4 0.094 12.6 0.2 1.4 1 0 0 1 1 1 0 Subtilisin inhibitor-like DUF3372 PF11852.3 EEB07073.1 - 0.1 11.7 0.2 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Stress-antifung PF01657.12 EEB07073.1 - 0.92 9.8 7.3 0.082 13.2 1.1 2.0 2 1 0 2 2 2 0 Salt stress response/antifungal GFO_IDH_MocA PF01408.17 EEB07074.1 - 1.6e-22 80.2 0.1 2.4e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEB07074.1 - 3.9e-10 39.5 0.0 6.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EEB07074.1 - 2.1e-05 24.9 0.1 3.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EEB07074.1 - 0.0094 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEB07074.1 - 0.082 13.3 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 EEB07074.1 - 0.16 12.4 0.2 0.41 11.1 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain MFS_1 PF07690.11 EEB07075.1 - 1.6e-32 112.5 27.7 1.6e-32 112.5 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GP41 PF00517.12 EEB07075.1 - 0.38 10.2 2.3 2.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Retroviral envelope protein Ribonucleas_3_3 PF14622.1 EEB07076.1 - 2.3e-23 82.5 0.1 3.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEB07076.1 - 5.7e-20 71.8 0.1 4.2e-19 69.0 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 EEB07076.1 - 1.6e-08 34.9 0.2 3.2e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF3049 PF11250.3 EEB07076.1 - 0.15 11.8 0.7 4 7.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) HhH-GPD PF00730.20 EEB07077.1 - 3e-13 50.0 0.0 4.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SAM_1 PF00536.25 EEB07077.1 - 0.015 15.4 0.1 0.082 13.0 0.0 2.1 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) IGR PF09597.5 EEB07077.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 IGR protein motif TAP35_44 PF07265.6 EEB07077.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 2-oxoacid_dh PF00198.18 EEB07078.1 - 4.6e-81 271.4 0.2 5.8e-81 271.1 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEB07078.1 - 1.4e-16 59.8 0.1 2.7e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EEB07078.1 - 3.9e-16 58.3 0.1 8.8e-16 57.2 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain YbaB_DNA_bd PF02575.11 EEB07078.1 - 0.036 13.9 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family MAT1 PF06391.8 EEB07079.1 - 0.082 12.4 4.0 0.1 12.1 2.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ndc1_Nup PF09531.5 EEB07079.1 - 0.15 10.4 3.2 0.18 10.1 2.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Allexi_40kDa PF05549.6 EEB07079.1 - 0.22 10.7 2.8 0.25 10.5 1.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Sec7 PF01369.15 EEB07080.1 - 2.1e-65 219.9 2.1 6.4e-65 218.3 1.5 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEB07080.1 - 5.4e-55 185.3 6.0 5.4e-55 185.3 4.1 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEB07080.1 - 3.6e-27 93.7 0.6 3.6e-27 93.7 0.4 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) GDPD PF03009.12 EEB07081.1 - 7.4e-29 101.0 0.0 1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.27 EEB07082.1 - 3.3e-47 156.7 18.6 1.5e-10 40.5 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EEB07082.1 - 1.6e-07 29.8 4.1 0.059 11.4 0.2 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EEB07082.1 - 4.3e-06 26.3 0.8 1.2e-05 24.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEB07082.1 - 1.5e-05 24.4 0.8 4e-05 23.1 0.6 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EEB07082.1 - 0.003 16.3 0.1 0.32 9.6 0.1 2.8 3 1 0 3 3 3 2 Nup133 N terminal like Prenyltransf PF01255.14 EEB07083.1 - 1.4e-83 279.4 0.1 1.6e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1707 PF08044.6 EEB07083.1 - 0.11 12.2 0.3 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) WD40 PF00400.27 EEB07084.1 - 2.8e-29 99.9 1.0 6.3e-09 35.3 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EEB07084.1 - 0.0019 17.7 0.4 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EEB07084.1 - 0.0043 15.2 0.1 0.021 12.9 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEB07084.1 - 0.066 11.4 0.0 0.22 9.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain MOZ_SAS PF01853.13 EEB07085.1 - 5.7e-84 280.0 1.0 8.3e-84 279.5 0.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family HTH_AsnC-type PF13404.1 EEB07085.1 - 0.024 14.1 0.1 0.49 9.9 0.0 2.3 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EEB07085.1 - 0.042 13.2 0.2 2.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_9 PF08221.6 EEB07085.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ALMT PF11744.3 EEB07085.1 - 0.1 11.2 0.3 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IF2_N PF04760.10 EEB07085.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Sec3_C_2 PF15278.1 EEB07086.1 - 3.6e-47 158.3 3.1 7.8e-47 157.3 2.1 1.6 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Sec3-PIP2_bind PF15277.1 EEB07086.1 - 2.6e-12 46.4 0.2 4.5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EEB07086.1 - 0.0003 19.0 3.4 0.00048 18.4 2.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 RNA_pol_Rpb1_4 PF05000.12 EEB07086.1 - 0.073 12.8 0.5 0.18 11.5 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 CagX PF03524.10 EEB07086.1 - 0.34 10.1 2.2 0.31 10.2 0.1 1.9 2 0 0 2 2 2 0 Conjugal transfer protein Gly_transf_sug PF04488.10 EEB07087.1 - 5.9e-22 77.9 0.2 1.5e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEB07087.1 - 5e-06 25.2 5.1 0.013 14.0 0.5 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EEB07087.1 - 0.00042 19.5 0.5 0.00065 18.9 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein FHA PF00498.21 EEB07088.1 - 1e-16 60.8 0.3 4.2e-16 58.8 0.1 2.2 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 EEB07088.1 - 8.6e-06 25.4 15.5 3.3e-05 23.6 10.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EEB07088.1 - 0.0045 17.0 10.3 0.027 14.5 6.3 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger Ribosomal_S19 PF00203.16 EEB07088.1 - 0.048 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19 zf-Apc11 PF12861.2 EEB07088.1 - 0.068 13.0 7.1 0.14 12.0 4.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EEB07088.1 - 0.49 10.1 13.0 1 9.1 9.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEB07088.1 - 0.8 9.7 16.1 3.4 7.7 10.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EEB07088.1 - 1.7 8.4 12.2 3.3 7.4 7.5 2.1 2 0 0 2 2 2 0 PHD-finger COMPASS-Shg1 PF05205.7 EEB07089.1 - 6.8e-22 77.7 3.0 8.2e-22 77.5 2.1 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1215 PF06744.7 EEB07089.1 - 0.0092 15.6 0.4 0.021 14.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1215) Herpes_UL92 PF03048.9 EEB07089.1 - 0.032 13.8 0.3 0.051 13.1 0.2 1.3 1 1 0 1 1 1 0 UL92 family EVC2_like PF12297.3 EEB07089.1 - 0.039 12.5 4.3 0.042 12.4 3.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4259 PF14078.1 EEB07089.1 - 0.052 14.0 1.9 1.3 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) DUF4168 PF13767.1 EEB07089.1 - 0.17 12.5 1.2 0.31 11.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) YtzH PF14165.1 EEB07089.1 - 0.17 12.1 1.9 0.34 11.1 0.0 2.1 2 1 0 2 2 2 0 YtzH-like protein GTP_EFTU PF00009.22 EEB07090.1 - 4.2e-52 176.3 0.1 9.6e-52 175.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEB07090.1 - 4.6e-14 52.0 0.0 1.5e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEB07090.1 - 6.8e-12 45.3 0.1 4.1e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEB07090.1 - 2.7e-09 36.7 0.0 6.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EEB07090.1 - 1.8e-06 27.5 0.0 1e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EEB07090.1 - 0.0015 18.4 0.1 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DNA_pol_E_B PF04042.11 EEB07091.1 - 4.9e-38 130.4 1.3 7.6e-38 129.8 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EEB07091.1 - 3e-36 125.2 4.5 4.4e-21 75.5 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal GXWXG PF14231.1 EEB07091.1 - 0.1 12.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 GXWXG protein RNA_Me_trans PF04252.8 EEB07091.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase GPI-anchored PF10342.4 EEB07092.1 - 1.5e-13 51.0 8.9 1.5e-13 51.0 6.2 3.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 EEB07092.1 - 0.1 11.9 25.7 0.13 11.6 17.8 1.2 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EEB07092.1 - 0.16 10.1 37.1 0.19 9.9 25.7 1.2 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 EEB07092.1 - 0.7 8.8 23.9 0.93 8.4 16.6 1.2 1 0 0 1 1 1 0 BUD22 TFIIA_gamma_N PF02268.11 EEB07093.2 - 1.8e-27 94.6 0.2 2.5e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EEB07093.2 - 3e-25 87.7 0.6 4.3e-25 87.2 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Malic_M PF03949.10 EEB07095.1 - 2.3e-79 266.5 0.0 3.3e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEB07095.1 - 6.8e-60 201.7 0.0 1.3e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ENTH PF01417.15 EEB07096.1 - 4.1e-48 162.3 0.9 9.4e-48 161.1 0.6 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EEB07096.1 - 6.6e-05 21.7 0.2 0.00013 20.7 0.1 1.5 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EEB07096.1 - 0.0082 15.7 0.2 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 VHS domain UDPGP PF01704.13 EEB07097.1 - 1.6e-165 550.7 0.0 1.8e-165 550.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF2419 PF10343.4 EEB07098.1 - 5.1e-14 52.2 0.0 7.7e-14 51.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1886 PF09171.5 EEB07098.1 - 0.026 13.5 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) PFL PF02901.10 EEB07098.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase GTP_EFTU PF00009.22 EEB07099.1 - 3.3e-57 192.9 0.8 5.3e-57 192.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEB07099.1 - 3.7e-37 126.4 0.0 9.2e-37 125.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEB07099.1 - 1.9e-16 59.9 2.0 1.9e-16 59.9 1.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEB07099.1 - 1.4e-05 24.5 0.5 4e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEB07099.1 - 0.00098 19.0 0.3 0.0033 17.3 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rep_fac_C PF08542.6 EEB07101.1 - 4.7e-19 68.1 0.8 1.5e-18 66.5 0.2 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EEB07101.1 - 1.9e-17 63.7 0.0 4.3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEB07101.1 - 2.4e-17 63.0 0.7 1.4e-14 54.1 0.1 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EEB07101.1 - 5.9e-10 38.4 0.1 7.5e-08 31.5 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EEB07101.1 - 2.4e-06 26.7 0.0 3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEB07101.1 - 3e-05 23.9 0.1 0.00013 21.8 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EEB07101.1 - 3.4e-05 23.5 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EEB07101.1 - 4.4e-05 22.5 0.0 6.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EEB07101.1 - 4.4e-05 23.1 0.1 9e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB07101.1 - 6.1e-05 23.1 2.2 0.16 12.1 0.0 3.2 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EEB07101.1 - 7.7e-05 22.7 0.1 0.00028 20.9 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EEB07101.1 - 9.3e-05 22.0 0.1 0.00042 19.8 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 EEB07101.1 - 0.00082 19.1 0.3 0.059 13.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EEB07101.1 - 0.0037 17.0 0.3 0.011 15.3 0.0 1.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_3 PF07726.6 EEB07101.1 - 0.0041 16.7 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEB07101.1 - 0.0097 15.3 0.2 1.8 7.9 0.0 2.8 1 1 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 EEB07101.1 - 0.011 15.2 0.0 0.037 13.4 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EEB07101.1 - 0.011 15.3 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEB07101.1 - 0.019 14.1 0.0 0.077 12.1 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EEB07101.1 - 0.024 14.0 0.2 0.13 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EEB07101.1 - 0.045 13.5 0.1 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEB07101.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EEB07101.1 - 0.084 12.4 0.0 0.7 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EEB07101.1 - 0.11 12.0 0.2 1 8.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase HATPase_c PF02518.21 EEB07102.1 - 6.1e-27 93.5 0.0 6.9e-26 90.1 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEB07102.1 - 1.2e-20 73.5 0.1 5.8e-20 71.3 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEB07102.1 - 1.9e-19 69.4 0.2 1e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EEB07102.1 - 8.4e-09 34.9 0.0 2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EEB07102.1 - 3.6e-07 30.3 0.0 1.8e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain PAS_9 PF13426.1 EEB07102.1 - 1.8e-06 28.2 0.0 2e-05 24.9 0.0 2.9 4 0 0 4 4 2 1 PAS domain PAS PF00989.19 EEB07102.1 - 2.4e-06 27.2 0.0 6.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EEB07102.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.1 EEB07102.1 - 0.00037 20.6 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain NACHT PF05729.7 EEB07102.1 - 0.00092 18.9 0.0 0.0088 15.7 0.0 2.8 2 1 0 2 2 2 1 NACHT domain PAS_3 PF08447.6 EEB07102.1 - 0.0035 17.3 0.1 0.016 15.3 0.0 2.2 2 0 0 2 2 1 1 PAS fold PAS_8 PF13188.1 EEB07102.1 - 0.0054 16.5 0.0 0.096 12.5 0.0 2.8 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EEB07102.1 - 0.021 15.3 0.0 0.071 13.5 0.0 2.0 2 0 0 2 2 1 0 GAF domain AAA_19 PF13245.1 EEB07102.1 - 0.39 10.5 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Ribosomal_S2 PF00318.15 EEB07103.1 - 2.1e-44 151.3 0.0 3.7e-23 81.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 CPSF_A PF03178.10 EEB07104.1 - 2.1e-79 266.9 0.2 6.3e-78 262.0 0.0 2.6 2 1 1 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EEB07104.1 - 7.8e-62 209.0 0.1 1.1e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Apc4 PF12896.2 EEB07105.1 - 1.1e-56 191.5 1.7 1.7e-56 190.8 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EEB07105.1 - 7e-14 51.0 0.1 1.7e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EEB07105.1 - 0.015 15.1 0.0 3.9 7.4 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4041 PF13250.1 EEB07105.1 - 0.042 13.3 0.1 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) MutL_C PF08676.6 EEB07106.2 - 8.3e-24 83.8 0.0 1.5e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EEB07106.2 - 1.3e-14 53.9 0.1 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEB07106.2 - 2.7e-10 39.9 0.0 5.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EEB07106.2 - 2.7e-10 39.7 0.0 6.7e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain eIF-5a PF01287.15 EEB07108.1 - 7.4e-27 93.0 0.2 1e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEB07108.1 - 1.8e-05 24.2 1.5 3.7e-05 23.2 1.0 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEB07108.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.17 EEB07110.1 - 2.5e-22 79.6 0.0 4.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEB07110.1 - 6.7e-16 58.1 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EEB07110.1 - 5.4e-06 26.7 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EEB07110.1 - 0.00083 19.6 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EEB07110.1 - 0.055 13.9 0.1 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_17 PF00332.13 EEB07111.1 - 7.1e-36 123.8 0.0 1.2e-35 123.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Lung_7-TM_R PF06814.8 EEB07112.1 - 6.2e-60 202.6 26.2 7.8e-60 202.3 18.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor LRR19-TM PF15176.1 EEB07112.1 - 0.12 12.1 1.0 4 7.1 0.1 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain POT1 PF02765.12 EEB07113.1 - 3.2e-18 66.0 0.0 7.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EEB07113.1 - 0.068 13.0 0.3 4.1 7.3 0.0 3.1 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Prefoldin_2 PF01920.15 EEB07114.1 - 0.0067 16.1 1.1 0.0067 16.1 0.8 2.9 2 1 1 3 3 3 2 Prefoldin subunit IF-2B PF01008.12 EEB07114.1 - 0.051 12.5 2.1 0.073 12.0 1.2 1.5 1 1 0 1 1 1 0 Initiation factor 2 subunit family Syntaxin PF00804.20 EEB07114.1 - 0.34 11.0 8.9 0.24 11.5 0.5 2.4 2 0 0 2 2 2 0 Syntaxin bZIP_1 PF00170.16 EEB07114.1 - 0.76 9.7 9.3 1.1 9.3 0.9 3.0 2 1 0 2 2 2 0 bZIP transcription factor TIG PF01833.19 EEB07115.1 - 8.7e-16 57.6 4.1 4.4e-15 55.4 2.8 2.3 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 EEB07115.1 - 2.6e-12 45.8 0.2 5.6e-06 25.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEB07115.1 - 2.5e-11 43.7 0.0 5.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEB07115.1 - 9.3e-10 38.4 0.3 5.5e-09 35.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB07115.1 - 1.6e-07 30.9 0.1 0.0036 17.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEB07115.1 - 3.9e-07 30.4 0.1 6.3e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Arm PF00514.18 EEB07116.1 - 9.6e-16 56.9 0.6 0.04 13.7 0.0 9.2 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEB07116.1 - 9.6e-12 45.0 0.1 0.00042 20.5 0.0 5.1 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EEB07116.1 - 1.2e-07 31.2 9.0 0.039 14.0 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.2 EEB07116.1 - 0.011 15.6 11.4 0.015 15.1 1.2 4.1 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EEB07116.1 - 0.018 15.4 6.7 24 5.5 0.0 6.2 6 1 0 6 6 6 0 HEAT-like repeat WD40 PF00400.27 EEB07117.1 - 2.5e-29 100.0 9.6 3.6e-06 26.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEB07117.1 - 2.1e-05 24.3 0.1 0.0075 15.9 0.0 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EEB07117.1 - 0.00086 18.7 1.1 0.0036 16.8 0.8 2.1 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EEB07117.1 - 0.0023 17.5 0.6 3.1 7.5 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat PQQ PF01011.16 EEB07117.1 - 0.04 13.4 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat MgsA_C PF12002.3 EEB07118.2 - 4.4e-57 192.4 0.1 9.2e-57 191.3 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 EEB07118.2 - 5e-16 58.4 0.0 3e-14 52.6 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EEB07118.2 - 2.5e-15 56.8 0.1 5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEB07118.2 - 8e-08 32.1 0.1 2.5e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEB07118.2 - 2.9e-06 27.1 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEB07118.2 - 3.9e-06 26.9 0.2 0.00079 19.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 EEB07118.2 - 9.1e-06 25.2 0.1 0.023 14.1 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 EEB07118.2 - 2.5e-05 24.4 0.3 0.00018 21.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EEB07118.2 - 0.00027 19.8 0.2 0.024 13.4 0.0 2.2 1 1 1 2 2 2 1 NB-ARC domain TIP49 PF06068.8 EEB07118.2 - 0.00031 19.6 0.3 0.0065 15.2 0.0 2.1 1 1 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EEB07118.2 - 0.0005 20.8 0.1 0.0021 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEB07118.2 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEB07118.2 - 0.0014 17.5 0.0 0.0035 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EEB07118.2 - 0.0018 18.0 0.5 2.7 7.6 0.2 2.9 1 1 1 2 2 2 2 Archaeal ATPase DUF258 PF03193.11 EEB07118.2 - 0.0036 16.5 0.1 0.0087 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEB07118.2 - 0.0041 17.4 0.1 0.014 15.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 EEB07118.2 - 0.0047 15.6 0.1 0.74 8.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 EEB07118.2 - 0.0062 16.2 0.7 4.7 6.8 0.0 3.0 2 1 1 3 3 3 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EEB07118.2 - 0.0087 15.2 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI zf-Di19 PF05605.7 EEB07118.2 - 0.0091 16.1 0.4 0.018 15.1 0.3 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding AAA_3 PF07726.6 EEB07118.2 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EEB07118.2 - 0.027 14.3 0.1 3.9 7.2 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EEB07118.2 - 0.028 14.4 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEB07118.2 - 0.032 14.5 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 EEB07118.2 - 0.033 14.0 0.1 0.081 12.7 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 EEB07118.2 - 0.04 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EEB07118.2 - 0.071 12.8 0.1 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EEB07118.2 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EEB07118.2 - 0.091 12.1 0.4 2.1 7.7 0.1 2.3 1 1 1 2 2 2 0 AAA-like domain DEAD PF00270.24 EEB07119.1 - 7.2e-26 90.6 0.0 1.5e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07119.1 - 2.4e-10 40.1 0.0 3.7e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EEB07119.1 - 3.5e-10 40.3 4.0 5.4e-10 39.7 1.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EEB07119.1 - 0.035 14.0 0.3 0.035 14.0 0.2 1.8 2 0 0 2 2 2 0 DNA replication factor CDT1 like DUF4264 PF14084.1 EEB07119.1 - 0.037 13.3 0.4 0.52 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) NCD1 PF04904.8 EEB07119.1 - 0.084 12.6 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Mit_ribos_Mrp51 PF11709.3 EEB07120.1 - 5e-19 68.6 0.1 1.2e-18 67.3 0.0 1.5 1 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit SH3_9 PF14604.1 EEB07121.1 - 1.5e-08 34.1 0.1 3.1e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEB07121.1 - 7.9e-08 31.6 0.1 2.3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EEB07121.1 - 9.9e-08 31.2 0.1 1.9e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain RPAP2_Rtr1 PF04181.8 EEB07122.1 - 3.8e-17 62.1 2.5 3.8e-17 62.1 1.7 1.7 2 0 0 2 2 2 1 Rtr1/RPAP2 family CCDC32 PF14989.1 EEB07122.1 - 0.07 12.9 3.8 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Sec20 PF03908.8 EEB07123.1 - 8.9e-22 76.6 1.8 8.9e-22 76.6 1.3 2.0 2 1 0 2 2 2 1 Sec20 CreD PF06123.7 EEB07123.1 - 0.016 13.7 0.1 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD Baculo_11_kDa PF06143.6 EEB07123.1 - 0.063 12.6 3.1 0.065 12.5 0.2 2.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family DivIVA PF05103.8 EEB07123.1 - 0.18 11.8 5.5 1 9.4 1.4 2.6 1 1 2 3 3 3 0 DivIVA protein PilJ PF13675.1 EEB07123.1 - 0.24 11.7 4.0 0.56 10.5 0.8 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cys_Met_Meta_PP PF01053.15 EEB07124.1 - 1.7e-65 220.7 0.3 6.5e-65 218.9 0.2 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEB07124.1 - 0.0039 16.1 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEB07124.1 - 0.047 12.4 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V B3_4 PF03483.12 EEB07126.1 - 1.8e-25 89.3 0.0 3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EEB07126.1 - 1e-16 60.5 0.0 8.5e-16 57.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EEB07126.1 - 0.058 12.4 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Ribosomal_L13 PF00572.13 EEB07127.1 - 4e-27 94.7 0.0 7.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 EEB07127.1 - 0.1 12.1 0.2 0.23 10.9 0.2 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain SecY PF00344.15 EEB07128.2 - 4.8e-50 170.4 11.7 6.5e-50 169.9 8.1 1.0 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEB07128.2 - 1.5e-06 27.6 0.3 7.1e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p Med26 PF08711.6 EEB07129.1 - 2.5e-14 52.5 0.0 7.4e-14 50.9 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TraC PF07820.7 EEB07129.1 - 0.18 12.0 3.6 0.17 12.1 0.5 2.4 2 0 0 2 2 2 0 TraC-like protein Tom5 PF10642.4 EEB07130.1 - 4.7e-06 26.1 1.4 5e-06 26.0 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EEB07131.1 - 1.4e-42 144.7 2.3 1.4e-42 144.7 1.6 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 V_ATPase_I PF01496.14 EEB07131.1 - 0.0085 14.0 1.2 0.012 13.4 0.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Nucleoporin_FG PF13634.1 EEB07131.1 - 0.059 13.6 71.8 0.14 12.4 34.8 3.2 1 1 1 2 2 2 0 Nucleoporin FG repeat region MbeD_MobD PF04899.7 EEB07131.1 - 0.32 10.9 3.0 8.6 6.3 0.1 3.5 2 1 1 3 3 3 0 MbeD/MobD like COG5 PF10392.4 EEB07132.1 - 1.4e-20 73.5 0.6 1.4e-20 73.5 0.4 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps53_N PF04100.7 EEB07132.1 - 0.0011 17.8 4.5 0.0015 17.4 3.1 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EEB07132.1 - 0.002 17.0 0.2 0.002 17.0 0.2 1.8 2 1 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) THP2 PF09432.5 EEB07132.1 - 0.033 14.0 1.6 0.058 13.2 0.1 2.1 2 1 0 2 2 2 0 Tho complex subunit THP2 Baculo_PEP_C PF04513.7 EEB07132.1 - 1.4 8.7 13.8 0.16 11.7 3.2 3.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRF PF08558.5 EEB07133.1 - 5.8e-66 222.2 0.0 8.1e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EEB07133.1 - 1.5e-06 28.1 0.2 2.9e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB07133.1 - 0.00028 20.9 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PAT1 PF09770.4 EEB07134.1 - 2.3e-187 624.8 10.8 9.5e-151 503.7 0.0 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Peptidase_C48 PF02902.14 EEB07135.1 - 1.1e-44 152.6 0.0 2.1e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 EEB07135.1 - 0.023 13.2 0.1 0.036 12.5 0.0 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Arrestin_C PF02752.17 EEB07136.1 - 2.9e-06 27.4 5.4 2.1e-05 24.6 0.2 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain UPF0300 PF08594.5 EEB07137.1 - 6.5e-37 126.5 0.4 1.1e-36 125.8 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) PPR_2 PF13041.1 EEB07138.1 - 2.9e-27 94.3 5.4 3.9e-11 42.7 0.1 6.9 4 1 3 7 7 7 4 PPR repeat family PPR PF01535.15 EEB07138.1 - 9.4e-17 59.7 7.1 3.8e-05 23.3 0.0 6.4 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 EEB07138.1 - 1.2e-09 37.6 1.6 2.4 8.6 0.0 5.8 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEB07138.1 - 9.3e-06 25.0 0.1 0.23 10.9 0.0 4.5 5 0 0 5 5 5 2 PPR repeat ATP13 PF12921.2 EEB07138.1 - 0.00031 20.0 1.6 2.1 7.7 0.0 4.0 3 1 0 3 3 3 2 Mitochondrial ATPase expression SRF-TF PF00319.13 EEB07139.1 - 1.2e-17 62.8 0.0 2.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glucan_synthase PF02364.10 EEB07140.1 - 0 1322.3 0.0 0 1321.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEB07140.1 - 1.2e-37 128.4 0.3 3.1e-37 127.0 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 UPF0542 PF15086.1 EEB07140.1 - 1.1 9.0 4.2 31 4.3 1.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 SprT-like PF10263.4 EEB07141.1 - 5.1e-40 136.7 0.6 5.1e-40 136.7 0.4 1.7 2 0 0 2 2 2 1 SprT-like family HMG_box PF00505.14 EEB07141.1 - 5.1e-07 29.8 0.1 2e-06 27.9 0.1 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.8 EEB07141.1 - 0.00031 21.0 1.9 0.00081 19.6 0.1 2.4 2 1 0 2 2 2 1 YABBY protein DUF1014 PF06244.7 EEB07141.1 - 0.0025 18.0 1.5 0.0063 16.7 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1014) Ribosomal_S30 PF04758.9 EEB07142.1 - 1.8e-28 98.0 4.1 2e-28 97.9 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_4 PF01063.14 EEB07143.1 - 6.4e-30 104.3 0.0 7.9e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV MutS_V PF00488.16 EEB07144.1 - 1.3e-95 319.3 0.1 2.1e-95 318.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEB07144.1 - 3.6e-35 121.6 1.5 5e-35 121.1 0.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EEB07144.1 - 1.3e-19 70.1 0.2 3.4e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EEB07144.1 - 5.2e-17 62.1 0.2 3.7e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EEB07144.1 - 1.4e-11 44.3 0.0 5.5e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain I Cache_1 PF02743.13 EEB07144.1 - 0.024 14.1 0.1 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 Cache domain G10 PF01125.12 EEB07145.1 - 4.8e-65 217.5 3.3 5.4e-65 217.3 2.3 1.0 1 0 0 1 1 1 1 G10 protein DUF2013 PF09431.5 EEB07146.1 - 4.6e-41 139.8 3.5 4.6e-40 136.6 0.5 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2013) COX6B PF02297.12 EEB07147.1 - 6.1e-21 74.2 3.6 7.8e-21 73.8 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EEB07147.1 - 0.033 14.2 0.3 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 XFP_N PF09364.5 EEB07148.1 - 6.1e-161 535.1 0.0 7.9e-161 534.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EEB07148.1 - 1.4e-70 236.4 0.0 2.3e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EEB07148.1 - 1.7e-62 210.4 0.0 2.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EEB07148.1 - 0.029 13.9 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Folliculin PF11704.3 EEB07149.2 - 3.5e-37 127.5 0.0 1.8e-36 125.2 0.0 1.9 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CDC14 PF08045.6 EEB07150.1 - 1.8e-53 181.3 0.4 1.5e-52 178.2 0.3 1.9 1 1 0 1 1 1 1 Cell division control protein 14, SIN component G-alpha PF00503.15 EEB07151.1 - 7e-100 334.4 0.0 7.7e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEB07151.1 - 7.1e-12 44.9 0.1 5.7e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EEB07151.1 - 0.0065 16.9 0.0 4.1 7.9 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEB07151.1 - 0.0082 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEB07151.1 - 0.087 12.7 0.0 15 5.5 0.0 2.5 2 1 1 3 3 3 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEB07151.1 - 0.11 11.6 0.5 4.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Coatomer_E PF04733.9 EEB07152.1 - 1.2e-42 146.0 2.9 1.8e-42 145.4 2.0 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EEB07152.1 - 0.0052 17.1 1.6 0.0052 17.1 1.1 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Aldedh PF00171.17 EEB07153.1 - 2.7e-106 355.6 0.0 3.4e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2b PF00587.20 EEB07154.1 - 1.3e-33 116.0 0.1 1.9e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEB07154.1 - 9.7e-11 41.4 0.0 4.9e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEB07154.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) zf-TFIIB PF13453.1 EEB07154.1 - 0.1 11.8 1.3 0.21 10.8 0.9 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger IFT57 PF10498.4 EEB07155.2 - 0.0012 17.6 2.8 0.0015 17.3 2.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1848 PF08902.6 EEB07155.2 - 0.04 13.4 0.6 0.056 12.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Ubiq_cyt_C_chap PF03981.7 EEB07155.2 - 0.066 13.0 0.1 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Mvb12 PF09452.5 EEB07155.2 - 0.081 13.1 0.5 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF3573 PF12097.3 EEB07155.2 - 0.23 10.0 1.3 0.32 9.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PUF PF00806.14 EEB07157.1 - 3.5e-53 174.1 11.3 3.6e-08 32.4 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 EEB07157.1 - 0.013 15.3 1.1 0.4 10.5 0.1 2.6 2 1 1 3 3 3 0 CPL (NUC119) domain BRCT PF00533.21 EEB07159.2 - 5.1e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB07159.2 - 1.3e-06 28.1 0.0 2.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 EEB07159.2 - 0.0067 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Synaptobrevin PF00957.16 EEB07160.1 - 4.2e-34 115.9 2.3 5e-34 115.7 1.6 1.1 1 0 0 1 1 1 1 Synaptobrevin NPV_P10 PF05531.7 EEB07160.1 - 0.028 14.6 0.3 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 EEB07160.1 - 0.085 12.5 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF515 PF04415.7 EEB07160.1 - 1.3 7.2 4.0 0.59 8.3 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF515) SEN1_N PF12726.2 EEB07161.1 - 1.2e-107 360.8 24.0 2.5e-107 359.7 16.6 1.6 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EEB07161.1 - 7.6e-68 228.6 0.9 7.6e-68 228.6 0.6 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEB07161.1 - 2.5e-62 209.8 0.4 8.5e-62 208.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEB07161.1 - 7.9e-13 47.9 0.0 3.3e-11 42.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEB07161.1 - 9.6e-07 28.5 0.0 0.0036 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EEB07161.1 - 2.8e-06 27.0 0.1 0.46 9.9 0.0 4.1 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EEB07161.1 - 0.00021 21.4 0.8 3.4 7.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain Helicase_RecD PF05127.9 EEB07161.1 - 0.0051 16.4 0.2 0.23 11.0 0.0 2.9 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EEB07161.1 - 0.012 15.8 1.8 0.36 11.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EEB07161.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_L24e PF01246.15 EEB07162.1 - 9.1e-30 102.3 0.3 9.1e-30 102.3 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e UCH PF00443.24 EEB07163.1 - 1e-47 162.5 0.2 1.3e-47 162.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB07163.1 - 3.7e-17 62.6 4.8 2.9e-16 59.7 3.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EEB07163.1 - 6.5e-14 51.0 0.1 1.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family PdxA PF04166.7 EEB07163.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA ARPC4 PF05856.7 EEB07164.1 - 1.5e-71 239.2 3.6 1.7e-71 239.0 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Microtub_assoc PF07989.6 EEB07165.1 - 5.4e-19 67.7 9.8 5.4e-19 67.7 6.8 14.0 10 2 5 15 15 14 1 Microtubule associated PACT_coil_coil PF10495.4 EEB07165.1 - 9.5e-18 63.9 0.5 5e-17 61.6 0.3 2.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cast PF10174.4 EEB07165.1 - 3.9e-06 25.2 37.5 3.9e-06 25.2 26.0 5.8 1 1 4 5 5 4 2 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 EEB07165.1 - 0.00015 21.4 24.8 0.00015 21.4 17.2 9.9 1 1 7 9 9 7 3 IncA protein Tropomyosin PF00261.15 EEB07165.1 - 0.00066 18.8 37.8 0.00066 18.8 26.2 6.9 3 2 3 7 7 7 2 Tropomyosin MAD PF05557.8 EEB07165.1 - 0.0014 16.8 41.1 0.0014 16.8 28.5 6.1 1 1 5 6 6 6 1 Mitotic checkpoint protein Atg14 PF10186.4 EEB07165.1 - 0.0038 16.2 20.5 0.0038 16.2 14.2 8.2 2 2 7 9 9 7 3 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EEB07165.1 - 0.0043 16.8 6.5 0.0043 16.8 4.5 16.3 6 3 13 19 19 16 4 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 EEB07165.1 - 0.0069 16.3 22.7 0.0069 16.3 15.8 9.4 2 2 6 8 8 3 1 Ciliary rootlet component, centrosome cohesion Pec_lyase_N PF04431.8 EEB07165.1 - 0.02 14.9 0.1 0.072 13.1 0.1 2.0 1 0 0 1 1 1 0 Pectate lyase, N terminus Reo_sigmaC PF04582.7 EEB07165.1 - 6.3 5.8 71.5 0.57 9.3 0.3 7.3 1 1 2 7 7 7 0 Reovirus sigma C capsid protein NUDIX PF00293.23 EEB07166.1 - 1.4e-09 37.6 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.15 EEB07167.1 - 3.8e-18 65.8 3.0 3.8e-18 65.8 2.1 2.2 2 0 0 2 2 2 1 Sec7 domain Pkinase PF00069.20 EEB07168.1 - 1.7e-71 240.4 0.0 1.9e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07168.1 - 1.3e-35 122.7 0.0 1.6e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07168.1 - 3.5e-09 36.0 0.1 3.1e-06 26.3 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EEB07168.1 - 2.2e-06 26.8 0.0 3.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEB07168.1 - 0.0051 16.1 0.5 0.015 14.6 0.3 1.8 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EEB07168.1 - 0.1 12.3 0.1 0.46 10.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1108 PF06531.6 EEB07168.1 - 0.17 12.0 1.4 9.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) PUF PF00806.14 EEB07169.1 - 3.8e-22 76.4 0.0 0.0044 16.4 0.1 8.6 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat FcoT PF10862.3 EEB07169.1 - 0.16 11.5 0.9 0.33 10.4 0.1 1.9 3 0 0 3 3 3 0 FcoT-like thioesterase domain DUF1764 PF08576.5 EEB07170.1 - 5e-20 72.1 7.1 8.7e-20 71.4 4.9 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) zf-C2H2 PF00096.21 EEB07171.1 - 1.1e-11 44.2 18.9 0.00011 22.3 2.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEB07171.1 - 1.3e-09 37.9 7.8 9.9e-05 22.4 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEB07171.1 - 5.1e-06 26.4 14.5 0.12 12.7 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEB07171.1 - 0.024 14.5 3.9 3.6 7.6 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEB07171.1 - 0.16 12.1 10.0 0.19 11.8 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB07171.1 - 0.58 10.4 8.3 0.32 11.2 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ubiquitin PF00240.18 EEB07172.1 - 3.4e-34 116.0 0.7 3.4e-34 116.0 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EEB07172.1 - 8.8e-25 86.2 2.1 1.6e-24 85.4 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EEB07172.1 - 2.5e-20 71.9 0.7 5e-20 70.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB07172.1 - 5.1e-06 26.6 0.4 6e-05 23.2 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB07172.1 - 0.00043 20.0 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB07172.1 - 0.00053 19.8 0.5 0.0011 18.7 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-ribbon_3 PF13248.1 EEB07172.1 - 0.0011 18.0 0.6 0.0023 17.0 0.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF2407 PF10302.4 EEB07172.1 - 0.0038 17.3 0.4 0.0051 16.9 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DZR PF12773.2 EEB07172.1 - 0.0082 15.9 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon Plexin_cytopl PF08337.7 EEB07172.1 - 0.014 13.7 3.1 0.21 9.8 0.2 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2318 PF10080.4 EEB07172.1 - 0.065 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc_ribbon_2 PF13240.1 EEB07172.1 - 0.088 12.3 2.9 0.28 10.7 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EEB07172.1 - 0.093 12.4 2.1 0.33 10.6 1.2 2.1 1 1 1 2 2 2 0 Nudix N-terminal UPF0547 PF10571.4 EEB07172.1 - 0.11 12.2 0.7 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 EEB07172.1 - 0.11 12.1 1.2 0.26 10.9 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EEB07172.1 - 0.15 11.9 1.3 0.24 11.2 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ARID PF01388.16 EEB07173.1 - 3.5e-17 62.0 0.0 1.6e-16 59.8 0.0 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain pKID PF02173.12 EEB07173.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 pKID domain BRF1 PF07741.8 EEB07173.1 - 0.83 9.9 13.6 0.91 9.7 4.0 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Spt20 PF12090.3 EEB07173.1 - 1.4 8.2 14.0 3.1 7.1 1.6 2.5 2 0 0 2 2 2 0 Spt20 family DUF4512 PF14975.1 EEB07173.1 - 9.4 7.1 7.2 2.9 8.7 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) LIM_bind PF01803.11 EEB07174.1 - 5.9e-57 192.5 1.9 5.9e-57 192.5 1.3 2.1 2 1 0 2 2 2 1 LIM-domain binding protein R3H PF01424.17 EEB07175.1 - 6.8e-13 48.1 0.1 3.7e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 R3H domain G-patch PF01585.18 EEB07175.1 - 1.7e-07 30.9 1.4 3.4e-07 29.9 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEB07175.1 - 0.051 13.4 0.4 0.051 13.4 0.3 3.1 3 0 0 3 3 3 0 DExH-box splicing factor binding site WSC PF01822.14 EEB07176.1 - 3.1e-13 49.4 8.9 3.1e-13 49.4 6.1 2.9 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 EEB07176.1 - 0.016 14.4 1.9 0.016 14.4 1.3 2.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EEB07176.1 - 0.076 12.6 8.7 0.21 11.2 6.0 1.6 1 1 0 1 1 1 0 Rifin/stevor family DUF1421 PF07223.6 EEB07176.1 - 0.11 12.2 17.9 0.15 11.8 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) EphA2_TM PF14575.1 EEB07176.1 - 0.25 11.7 1.6 0.38 11.1 0.0 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 EEB07176.1 - 2 7.7 12.5 19 4.5 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF605 PF04652.11 EEB07176.1 - 2.7 7.2 24.6 3.6 6.8 17.1 1.1 1 0 0 1 1 1 0 Vta1 like Asp PF00026.18 EEB07177.1 - 4.4e-65 220.0 15.1 7.8e-65 219.1 10.5 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEB07177.1 - 2.7e-09 37.1 0.3 2.4e-08 34.0 0.0 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EEB07177.1 - 0.00079 19.0 3.9 0.015 14.8 0.0 3.3 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EEB07177.1 - 0.0008 19.8 3.4 3 8.3 0.0 4.1 3 1 1 4 4 4 2 Aspartyl protease NUDIX_4 PF14815.1 EEB07178.1 - 2.6e-16 59.0 0.1 5.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 EEB07178.1 - 5.7e-15 55.5 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEB07178.1 - 0.00021 20.7 0.1 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF1767 PF08585.7 EEB07179.1 - 7.8e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DUF4035 PF13227.1 EEB07179.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) tRNA_bind PF01588.15 EEB07180.1 - 2.7e-27 94.4 0.0 5.6e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EEB07180.1 - 0.017 15.5 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.7 EEB07180.1 - 0.017 15.1 2.3 0.027 14.4 1.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 EEB07180.1 - 0.94 8.1 13.6 1.4 7.5 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GST_C PF00043.20 EEB07180.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.8 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Cornichon PF03311.9 EEB07181.1 - 3.1e-46 156.6 11.1 3.4e-46 156.5 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Tubulin_3 PF14881.1 EEB07182.1 - 1.1e-33 116.1 0.2 1.9e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EEB07182.1 - 1.2e-29 102.7 0.0 2.6e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain 14-3-3 PF00244.15 EEB07183.1 - 7.6e-115 381.9 8.1 9.7e-115 381.5 5.6 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EEB07183.1 - 0.0012 18.3 1.2 1.1 8.7 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF837) DUF3802 PF12290.3 EEB07183.1 - 0.17 12.1 1.1 1.2 9.5 0.1 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3802) Rad51 PF08423.6 EEB07184.2 - 3.2e-121 403.0 0.2 4.2e-121 402.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EEB07184.2 - 6.4e-14 51.7 0.1 8.7e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EEB07184.2 - 2.2e-09 37.0 0.0 3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEB07184.2 - 5e-07 29.0 0.2 9.7e-07 28.1 0.1 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EEB07184.2 - 4.9e-06 26.6 0.1 1.3e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF128 PF01995.11 EEB07184.2 - 0.064 12.1 0.1 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF128 Abhydrolase_2 PF02230.11 EEB07185.1 - 4.9e-64 215.7 0.0 5.9e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEB07185.1 - 3.6e-11 42.9 0.0 4.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB07185.1 - 9e-07 28.9 0.1 5.3e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEB07185.1 - 0.00075 19.0 0.0 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EEB07185.1 - 0.023 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.4 EEB07185.1 - 0.11 11.3 0.2 8.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) TBCA PF02970.11 EEB07187.1 - 4.9e-17 61.7 2.1 6.2e-17 61.4 1.3 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Phage_Gp23 PF10669.4 EEB07187.1 - 0.0073 16.4 1.4 0.01 15.9 1.0 1.3 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Toxin_52 PF15605.1 EEB07187.1 - 0.049 13.5 0.2 0.32 10.9 0.0 1.9 1 1 1 2 2 2 0 Putative toxin 52 Spc7 PF08317.6 EEB07187.1 - 0.091 11.4 1.0 0.12 11.0 0.6 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Ank_2 PF12796.2 EEB07188.1 - 5.8e-06 26.5 0.9 3e-05 24.2 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEB07188.1 - 0.00034 20.5 1.7 2.4 8.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EEB07188.1 - 0.0011 18.6 1.2 0.43 10.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF4287 PF14117.1 EEB07188.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4287) Methyltransf_23 PF13489.1 EEB07188.1 - 0.02 14.6 0.0 0.058 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RasGAP_C PF03836.10 EEB07188.1 - 0.057 13.0 0.3 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Methyltransf_16 PF10294.4 EEB07188.1 - 0.097 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Nsp1_C PF05064.8 EEB07190.1 - 1.8e-34 117.8 3.4 4.2e-34 116.6 2.4 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Laminin_II PF06009.7 EEB07190.1 - 0.067 12.9 2.7 8.4 6.1 0.0 2.5 1 1 2 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EEB07190.1 - 0.38 10.5 5.8 0.63 9.8 2.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EEB07190.1 - 0.51 10.6 2.0 5.9 7.2 0.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.7 EEB07190.1 - 0.53 10.5 5.6 4 7.7 0.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EEB07190.1 - 1.3 9.4 4.1 1.3 9.5 0.7 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Nucleoporin_FG PF13634.1 EEB07190.1 - 6.8 6.9 165.5 0.51 10.5 36.6 4.6 1 1 2 3 3 3 0 Nucleoporin FG repeat region TMF_DNA_bd PF12329.3 EEB07190.1 - 7.8 6.3 6.8 7.7 6.4 0.6 3.0 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1748 PF08520.5 EEB07191.1 - 4.5e-24 83.8 0.1 4.8e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) XRN_N PF03159.13 EEB07192.1 - 4.3e-105 350.3 0.2 9.5e-105 349.2 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus CN_hydrolase PF00795.17 EEB07193.1 - 3e-34 117.9 0.0 4.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_5 PF13854.1 EEB07193.1 - 0.05 13.5 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Kelch motif ArfGap PF01412.13 EEB07194.1 - 1.1e-33 115.4 1.0 3.3e-33 113.9 0.7 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EEB07194.1 - 2.4e-14 53.3 1.1 9.8e-14 51.4 0.8 2.1 1 0 0 1 1 1 1 PH domain ACDC PF14733.1 EEB07194.1 - 0.029 14.4 0.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 AP2-coincident C-terminal RhoGAP PF00620.22 EEB07195.1 - 9.2e-41 138.9 0.0 2.8e-40 137.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EEB07195.1 - 0.00012 22.2 0.0 0.00051 20.1 0.0 2.1 1 0 0 1 1 1 1 PH domain LSM PF01423.17 EEB07196.1 - 3e-19 68.3 0.1 3.7e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB07196.1 - 0.0058 16.5 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_L5_C PF00673.16 EEB07197.1 - 5e-23 80.6 0.0 7.1e-23 80.1 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEB07197.1 - 3e-20 71.7 0.1 8.3e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 WBS_methylT PF12589.3 EEB07198.1 - 6.5e-17 61.7 6.0 1.1e-16 61.0 4.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EEB07198.1 - 9.3e-12 45.2 0.0 3.1e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07198.1 - 1.6e-09 37.6 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB07198.1 - 1.8e-08 34.1 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07198.1 - 3.5e-07 30.7 0.0 7.6e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB07198.1 - 4.6e-07 30.1 0.0 9.5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB07198.1 - 8.9e-06 25.7 0.0 2.4e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB07198.1 - 1.4e-05 25.5 0.1 0.00013 22.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EEB07198.1 - 0.00011 21.4 0.3 0.00026 20.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EEB07198.1 - 0.00037 19.6 0.0 0.0014 17.8 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EEB07198.1 - 0.00056 19.5 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EEB07198.1 - 0.0059 15.7 0.0 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EEB07198.1 - 0.011 15.3 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EEB07198.1 - 0.027 13.8 0.0 0.069 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.13 EEB07198.1 - 0.09 12.2 1.2 1.4 8.3 0.0 2.3 2 1 0 2 2 2 0 DNA methylase Clathrin PF00637.15 EEB07199.1 - 9.2e-201 657.5 43.6 2.6e-33 114.6 1.7 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EEB07199.1 - 1.2e-31 108.3 0.1 5.8e-31 106.1 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EEB07199.1 - 2.5e-25 86.9 3.8 1.2e-05 25.2 0.1 6.7 6 0 0 6 6 6 5 Clathrin propeller repeat Coatomer_WDAD PF04053.9 EEB07199.1 - 2.4e-06 26.6 6.1 0.004 15.9 0.1 5.0 4 1 1 6 6 6 2 Coatomer WD associated region TPR_7 PF13176.1 EEB07199.1 - 3.8e-06 26.2 3.3 9 6.3 0.0 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB07199.1 - 0.00037 20.2 3.5 2.5 8.2 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB07199.1 - 0.00045 20.5 16.7 10 7.0 0.0 10.3 10 2 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB07199.1 - 0.0045 16.5 2.9 5.4 6.8 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EEB07199.1 - 0.0057 15.6 0.1 0.017 14.1 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 EEB07199.1 - 0.0086 15.9 7.9 2 8.4 0.0 6.3 7 1 0 7 7 7 1 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 EEB07200.1 - 4.4e-54 181.6 1.0 5.5e-54 181.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ribonuclease_P PF00825.13 EEB07201.2 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease P HEAT_2 PF13646.1 EEB07202.1 - 5.4e-39 132.3 0.1 3.3e-16 59.3 0.0 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EEB07202.1 - 5.7e-27 91.4 0.0 8e-05 22.7 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EEB07202.1 - 9.5e-09 34.6 0.5 0.0085 16.0 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EEB07202.1 - 4.1e-08 33.4 1.4 0.0073 16.7 0.0 4.2 3 2 1 4 4 4 2 HEAT-like repeat Arm PF00514.18 EEB07202.1 - 9.3e-05 22.1 0.1 0.041 13.7 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF310 PF03750.8 EEB07202.1 - 0.01 16.0 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF310) DUF1546 PF07571.8 EEB07202.1 - 0.074 13.1 0.0 4.1 7.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) RuvA_C PF07499.8 EEB07202.1 - 0.088 12.9 1.2 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain DHC_N1 PF08385.7 EEB07203.1 - 2.3e-91 306.9 19.4 2.3e-91 306.9 13.4 5.4 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EEB07203.1 - 1.7e-79 267.2 6.9 1.7e-79 267.2 4.8 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EEB07203.1 - 1.1e-72 245.1 0.1 2.4e-72 244.0 0.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EEB07203.1 - 1.6e-59 201.2 0.1 8.4e-59 198.8 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EEB07203.1 - 3e-31 108.0 0.0 9.4e-12 44.8 0.0 5.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) MT PF12777.2 EEB07203.1 - 1.3e-30 106.3 6.8 1.3e-30 106.3 4.7 3.4 4 0 0 4 4 4 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 EEB07203.1 - 4.4e-19 68.6 0.1 7.9e-17 61.2 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 EEB07203.1 - 1.2e-15 57.8 0.2 0.027 14.6 0.0 6.5 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.2 EEB07203.1 - 2.2e-14 53.1 0.0 6.6e-14 51.5 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_22 PF13401.1 EEB07203.1 - 7.1e-14 52.0 0.1 0.023 14.8 0.0 6.3 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.1 EEB07203.1 - 1.5e-09 38.0 1.8 0.44 10.5 0.0 6.2 6 0 0 6 6 4 3 AAA ATPase domain AAA_9 PF12781.2 EEB07203.1 - 1.8e-09 36.7 0.9 1.8e-09 36.7 0.6 2.7 4 0 0 4 4 4 1 ATP-binding dynein motor region D5 AAA_17 PF13207.1 EEB07203.1 - 1.5e-08 35.4 0.3 0.092 13.5 0.0 4.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EEB07203.1 - 8.9e-08 32.4 0.8 0.00081 19.6 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEB07203.1 - 1.1e-07 31.8 0.0 0.11 12.3 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EEB07203.1 - 6.1e-07 29.1 0.0 0.2 11.3 0.0 3.9 4 0 0 4 4 3 2 Part of AAA domain RNA_helicase PF00910.17 EEB07203.1 - 8.3e-06 25.9 0.4 2.9 8.1 0.0 5.1 4 0 0 4 4 4 2 RNA helicase Mg_chelatase PF01078.16 EEB07203.1 - 0.0002 20.6 1.9 0.36 9.9 0.0 3.7 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EEB07203.1 - 0.00025 20.4 0.0 3.2 7.3 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EEB07203.1 - 0.0014 18.9 7.5 1.6 9.0 0.0 5.5 5 0 0 5 5 4 1 ABC transporter AAA_28 PF13521.1 EEB07203.1 - 0.004 17.1 0.0 3.5 7.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EEB07203.1 - 0.0049 15.9 0.0 1.8 7.6 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin FtsK_SpoIIIE PF01580.13 EEB07203.1 - 0.021 14.3 0.0 2.7 7.4 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EEB07203.1 - 0.04 13.6 0.6 3.9 7.1 0.1 3.4 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.1 EEB07203.1 - 0.089 12.1 0.1 6.7 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEB07203.1 - 0.13 11.7 2.7 6.6 6.2 0.1 3.9 5 0 0 5 5 5 0 AAA domain ArgK PF03308.11 EEB07203.1 - 0.3 9.8 0.1 0.7 8.6 0.0 1.6 1 0 0 1 1 1 0 ArgK protein DUF1664 PF07889.7 EEB07203.1 - 1.3 8.8 12.7 0.14 11.9 0.7 4.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.24 EEB07204.1 - 5.3e-44 149.6 0.0 1e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEB07204.1 - 7.1e-24 83.1 0.0 1.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEB07204.1 - 3.8e-22 77.9 0.0 9.4e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EEB07204.1 - 0.00082 19.3 0.2 0.0036 17.2 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain PolyA_pol PF01743.15 EEB07205.2 - 9.1e-25 87.3 0.0 1.8e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEB07205.2 - 2.5e-09 36.5 0.0 4.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Syja_N PF02383.13 EEB07206.1 - 1.2e-84 283.7 0.0 7.7e-84 281.1 0.0 2.1 2 0 0 2 2 2 1 SacI homology domain Meth_synt_2 PF01717.13 EEB07207.2 - 2.3e-145 483.6 0.0 6.8e-140 465.6 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEB07207.2 - 2.1e-127 424.6 0.0 8.2e-116 386.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Steroid_dh PF02544.11 EEB07208.1 - 6.5e-33 113.6 4.3 5.3e-26 91.1 1.2 2.3 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EEB07208.1 - 8e-06 25.3 0.1 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2177 PF09945.4 EEB07208.1 - 0.012 15.5 3.1 0.13 12.2 0.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) ICMT PF04140.9 EEB07208.1 - 0.034 14.3 0.1 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TGS PF02824.16 EEB07209.1 - 2.2e-22 78.6 0.0 4.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEB07209.1 - 2.8e-17 62.7 0.1 7e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB07209.1 - 3.4e-09 36.1 0.1 1.2e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB07209.1 - 0.0052 16.6 1.9 0.09 12.5 0.0 2.5 2 1 0 3 3 3 1 Dynamin family Miro PF08477.8 EEB07209.1 - 0.0077 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EEB07209.1 - 0.021 13.6 0.7 0.054 12.2 0.3 1.8 2 0 0 2 2 2 0 ArgK protein DUF2639 PF11121.3 EEB07209.1 - 0.033 13.7 0.2 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) Aldolase_II PF00596.16 EEB07210.2 - 5.2e-18 65.3 0.0 6.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ResIII PF04851.10 EEB07211.1 - 1.6e-21 76.9 0.0 3.3e-20 72.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEB07211.1 - 4.9e-21 74.9 0.0 2e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07211.1 - 3.2e-19 68.5 0.1 8.8e-19 67.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB07211.1 - 0.02 15.0 0.0 0.063 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEB07211.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec63 PF02889.11 EEB07212.1 - 2.7e-187 621.4 2.3 3.4e-106 355.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEB07212.1 - 4.3e-47 159.7 0.3 8.5e-30 103.4 0.1 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EEB07212.1 - 1.6e-13 50.9 0.0 2.4e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEB07212.1 - 1.1e-09 37.9 0.0 3.1e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB07212.1 - 4.1e-06 26.9 0.1 0.019 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EEB07212.1 - 0.027 13.6 0.0 6.7 5.8 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Acetyltransf_7 PF13508.1 EEB07213.1 - 5e-10 39.3 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB07213.1 - 5.8e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EEB07213.1 - 2.5e-07 30.5 0.0 0.00027 20.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB07213.1 - 3e-05 23.6 0.0 7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EEB07213.1 - 0.00092 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EEB07213.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB07213.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEB07213.1 - 0.004 17.0 0.0 0.0091 15.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NPDC1 PF06809.6 EEB07213.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Acetyltransf_3 PF13302.1 EEB07213.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain G6PD_C PF02781.11 EEB07214.1 - 4.1e-118 393.5 0.0 5.6e-118 393.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEB07214.1 - 2.4e-63 213.6 0.0 3.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Exo_endo_phos PF03372.18 EEB07215.1 - 2.3e-21 76.8 0.0 3.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EEB07215.1 - 1.4e-12 47.2 0.0 3.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EEB07215.1 - 0.0011 18.8 7.9 0.0073 16.2 5.5 2.3 1 1 0 1 1 1 1 GRF zinc finger zf-RING_2 PF13639.1 EEB07216.1 - 1.3e-11 44.0 6.6 1.3e-11 44.0 4.6 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB07216.1 - 5.2e-11 42.0 4.9 9e-11 41.2 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB07216.1 - 6.3e-09 35.3 7.0 6.3e-09 35.3 4.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07216.1 - 2.3e-08 33.6 6.7 4.7e-08 32.6 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEB07216.1 - 2.3e-08 33.9 7.5 5e-08 32.8 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB07216.1 - 0.0005 19.8 8.1 0.0005 19.8 5.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EEB07216.1 - 0.001 18.8 1.0 0.0017 18.1 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEB07216.1 - 0.011 15.2 6.0 0.021 14.4 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EEB07216.1 - 0.014 15.1 2.3 0.026 14.2 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EEB07216.1 - 0.016 14.8 1.9 0.016 14.8 1.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EEB07216.1 - 0.023 14.7 4.6 0.11 12.5 3.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EEB07216.1 - 0.074 12.6 4.5 0.93 9.0 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 EEB07216.1 - 0.11 12.3 5.7 0.27 11.0 4.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 EEB07217.2 - 2.7e-71 233.1 31.0 1.1e-08 34.5 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EEB07217.2 - 1.5e-20 73.1 0.0 3.7e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EEB07217.2 - 3.6e-05 22.1 7.8 0.048 11.7 0.0 5.0 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB07217.2 - 0.00024 19.9 0.3 3.3 6.3 0.0 4.1 2 2 1 3 3 3 3 Nup133 N terminal like UTP15_C PF09384.5 EEB07217.2 - 0.0089 15.7 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 UTP15 C terminal Thioredoxin PF00085.15 EEB07218.1 - 1.1e-33 114.9 0.1 5.9e-16 58.0 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EEB07218.1 - 6.8e-24 84.6 1.5 2.5e-08 33.9 0.1 4.1 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEB07218.1 - 1.6e-05 25.0 2.4 0.13 12.4 0.0 4.1 4 1 0 4 4 4 2 Thioredoxin-like domain HyaE PF07449.6 EEB07218.1 - 0.00052 19.8 0.0 2 8.3 0.0 3.3 4 0 0 4 4 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EEB07218.1 - 0.00061 19.5 0.5 1.2 9.0 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin domain Thioredoxin_8 PF13905.1 EEB07218.1 - 0.001 19.1 3.0 0.33 11.1 0.0 4.5 4 1 1 5 5 5 1 Thioredoxin-like Calsequestrin PF01216.12 EEB07218.1 - 0.001 17.9 0.3 0.0016 17.2 0.2 1.4 1 0 0 1 1 1 1 Calsequestrin DIM1 PF02966.11 EEB07218.1 - 0.12 11.9 1.6 5.2 6.5 0.0 2.5 1 1 0 2 2 2 0 Mitosis protein DIM1 EphA2_TM PF14575.1 EEB07218.1 - 0.91 9.9 4.7 0.39 11.1 0.1 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TrmE_N PF10396.4 EEB07219.1 - 2.6e-38 130.5 0.0 6.8e-38 129.1 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EEB07219.1 - 7.3e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EEB07219.1 - 3.1e-14 53.1 0.5 9.4e-14 51.5 0.4 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 EEB07219.1 - 3.7e-08 33.3 0.1 1e-05 25.4 0.0 2.5 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 EEB07219.1 - 0.00071 18.7 0.0 0.0019 17.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EEB07219.1 - 0.00073 18.7 0.1 0.0046 16.0 0.0 2.1 1 1 1 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EEB07219.1 - 0.0011 18.4 0.1 0.037 13.4 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEB07219.1 - 0.0017 17.6 0.0 0.005 16.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 EEB07219.1 - 0.0039 17.4 0.2 0.024 14.9 0.0 2.4 2 1 0 2 2 2 1 ABC transporter Arf PF00025.16 EEB07219.1 - 0.0071 15.5 0.1 0.23 10.6 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_28 PF13521.1 EEB07219.1 - 0.0089 16.0 0.0 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EEB07219.1 - 0.024 15.1 0.0 0.071 13.6 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein cobW PF02492.14 EEB07219.1 - 0.026 13.9 0.0 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rep-A_N PF04057.7 EEB07219.1 - 0.032 14.0 0.1 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain AAA_29 PF13555.1 EEB07219.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEB07219.1 - 0.12 11.7 0.3 7.4 5.9 0.0 2.4 1 1 0 2 2 2 0 AAA domain YL1_C PF08265.6 EEB07220.1 - 2.2e-16 59.0 0.3 8.3e-16 57.2 0.1 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Acyl-CoA_ox_N PF14749.1 EEB07220.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal LSM PF01423.17 EEB07221.1 - 1.7e-17 62.7 0.6 2.2e-17 62.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain Aminotran_1_2 PF00155.16 EEB07222.1 - 8e-57 192.8 0.0 9.8e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEB07222.1 - 7.1e-05 22.0 0.0 9.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEB07222.1 - 0.00034 19.4 0.0 0.0005 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EEB07222.1 - 0.016 13.7 0.1 0.073 11.6 0.0 2.0 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 EEB07222.1 - 0.11 11.5 0.0 0.26 10.2 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyoxalase_5 PF14696.1 EEB07222.1 - 0.13 12.1 0.2 1.3 8.9 0.1 2.5 2 1 1 3 3 3 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal GCV_T PF01571.16 EEB07223.2 - 8.4e-15 54.6 0.0 7.8e-11 41.7 0.0 2.1 1 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEB07223.2 - 0.01 15.8 0.0 0.044 13.8 0.0 2.0 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain IF-2B PF01008.12 EEB07224.1 - 2.1e-85 286.1 0.0 2.9e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pro_isomerase PF00160.16 EEB07225.1 - 3.5e-47 160.4 0.0 7.4e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EEB07225.1 - 3.3e-07 29.7 0.1 3.3e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger Acetyltransf_1 PF00583.19 EEB07226.1 - 1.2e-09 38.0 0.1 2.9e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEB07226.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB07226.1 - 7.7e-05 22.3 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EEB07226.1 - 8.6e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEB07226.1 - 0.00034 20.7 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB07226.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEB07226.1 - 0.0032 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase bZIP_1 PF00170.16 EEB07227.1 - 2.3e-08 33.8 9.5 2.3e-08 33.8 6.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EEB07227.1 - 3.5e-06 26.7 9.7 3.5e-06 26.7 6.7 3.8 4 0 0 4 4 4 1 Basic region leucine zipper HTH_WhiA PF02650.9 EEB07227.1 - 0.22 11.9 0.2 0.22 11.9 0.2 2.6 3 0 0 3 3 3 0 WhiA C-terminal HTH domain Ribosomal_L2_C PF03947.13 EEB07228.1 - 1.9e-38 131.1 2.7 3.4e-38 130.3 1.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEB07228.1 - 6.7e-14 51.6 0.1 1.4e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain 2-Hacid_dh_C PF02826.14 EEB07229.1 - 5.9e-48 162.3 0.0 9.3e-48 161.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEB07229.1 - 2.7e-40 136.9 0.0 3.8e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEB07229.1 - 9.3e-05 22.3 0.0 0.00028 20.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EEB07229.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EEB07229.1 - 0.053 13.0 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 0 ACT domain NAP PF00956.13 EEB07230.1 - 9.2e-77 257.4 8.1 9.2e-77 257.4 5.6 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) CASP_C PF08172.7 EEB07232.1 - 2.5e-42 144.6 13.3 2.5e-42 144.6 9.2 5.1 2 2 1 3 3 3 1 CASP C terminal GAS PF13851.1 EEB07232.1 - 0.0032 16.6 84.9 0.68 9.0 6.4 6.3 3 1 3 6 6 6 5 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EEB07232.1 - 0.014 14.8 4.2 0.014 14.8 2.9 8.7 5 3 3 8 8 8 0 Septum formation initiator CCDC155 PF14662.1 EEB07232.1 - 0.028 14.0 0.9 0.028 14.0 0.6 5.2 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 Filament PF00038.16 EEB07232.1 - 0.054 12.9 77.1 0.0091 15.4 12.8 4.2 3 1 1 4 4 4 0 Intermediate filament protein Acyl-CoA_dh_2 PF08028.6 EEB07232.1 - 0.41 10.8 0.0 0.41 10.8 0.0 3.7 4 1 0 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain MDH PF02315.11 EEB07232.1 - 0.81 9.6 6.3 3 7.8 0.1 3.1 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit Es2 PF09751.4 EEB07233.1 - 7.7e-17 61.8 4.1 3.7e-07 29.9 0.0 3.4 1 1 2 3 3 3 3 Nuclear protein Es2 Gag_p24 PF00607.15 EEB07233.1 - 0.08 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) BRE1 PF08647.6 EEB07235.1 - 2.9e-10 39.9 6.2 2.9e-10 39.9 4.3 6.0 6 2 0 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EEB07235.1 - 4.7e-08 32.9 9.7 1e-07 31.8 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB07235.1 - 4e-06 26.3 8.3 1.2e-05 24.8 5.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB07235.1 - 4.1e-05 23.1 10.3 8.6e-05 22.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB07235.1 - 0.00017 21.3 9.3 0.00017 21.3 6.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EEB07235.1 - 0.00029 20.5 11.7 0.00069 19.2 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EEB07235.1 - 0.0042 17.1 6.4 0.011 15.8 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEB07235.1 - 0.1 12.4 3.7 0.2 11.5 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEB07235.1 - 0.1 12.3 5.6 0.39 10.4 3.8 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 EEB07235.1 - 0.31 10.5 5.9 0.79 9.2 0.0 4.2 3 0 0 3 3 3 0 Rad50 zinc hook motif AAA_10 PF12846.2 EEB07235.1 - 0.43 9.9 7.7 0.22 10.9 0.2 2.5 2 1 0 2 2 2 0 AAA-like domain Prok-RING_4 PF14447.1 EEB07235.1 - 0.7 9.4 5.5 2.3 7.8 3.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EEB07235.1 - 0.73 9.7 11.8 0.38 10.6 5.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EEB07235.1 - 0.92 9.1 10.3 0.83 9.2 5.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Sec8_exocyst PF04048.9 EEB07236.1 - 1.8e-26 92.5 3.3 5.7e-26 90.8 2.3 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EEB07236.1 - 2.3e-08 33.2 5.7 2.3e-08 33.2 3.9 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) LEDGF PF11467.3 EEB07236.1 - 0.18 11.5 3.5 0.26 11.0 0.1 3.0 4 0 0 4 4 4 0 Lens epithelium-derived growth factor (LEDGF) ParcG PF10274.4 EEB07236.1 - 0.28 11.0 3.8 0.38 10.6 0.1 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein IPK PF03770.11 EEB07237.1 - 2.9e-55 186.9 0.0 5.7e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF221 PF02714.10 EEB07238.1 - 1.3e-74 250.9 21.7 1.3e-74 250.9 15.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEB07238.1 - 4.6e-33 113.9 0.7 4.6e-33 113.9 0.5 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEB07238.1 - 1.1e-15 57.9 0.7 1.8e-15 57.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RIIa PF02197.12 EEB07238.1 - 0.28 10.6 1.0 0.55 9.7 0.7 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Oxysterol_BP PF01237.13 EEB07239.2 - 6.7e-79 264.9 0.0 8.3e-79 264.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ribosomal_S16 PF00886.14 EEB07240.1 - 2.5e-21 75.1 0.0 3.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 HLH PF00010.21 EEB07241.1 - 4.8e-16 58.1 0.0 9.5e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KxDL PF10241.4 EEB07241.1 - 0.01 15.6 1.0 0.01 15.6 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DeoC PF01791.4 EEB07242.1 - 0.09 12.0 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 DeoC/LacD family aldolase Hydrolase_6 PF13344.1 EEB07243.1 - 2.9e-24 84.8 0.0 1.5e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB07243.1 - 6.4e-22 77.0 0.0 2.2e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEB07243.1 - 3.9e-05 23.9 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB07243.1 - 0.0048 17.3 0.0 0.14 12.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EEB07244.1 - 1.2e-52 174.0 17.5 2.4e-14 52.5 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEB07244.1 - 2.8e-11 42.2 12.7 0.00039 18.7 0.0 5.4 2 1 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB07244.1 - 2.6e-05 23.1 3.0 0.038 12.7 0.0 3.9 1 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 EEB07244.1 - 0.0017 17.9 0.3 0.8 9.1 0.0 2.7 2 1 0 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 EEB07244.1 - 0.0045 16.1 0.9 0.72 8.8 0.0 2.8 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal RicinB_lectin_2 PF14200.1 EEB07244.1 - 0.02 15.2 0.2 66 3.9 0.2 3.9 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like IKI3 PF04762.7 EEB07244.1 - 0.038 11.8 0.2 0.36 8.6 0.0 2.1 2 1 0 2 2 2 0 IKI3 family Hira PF07569.6 EEB07244.1 - 0.17 11.0 2.0 18 4.4 0.1 3.5 2 1 3 5 5 5 0 TUP1-like enhancer of split SecY PF00344.15 EEB07245.1 - 2.1e-91 306.4 9.2 2.7e-91 306.0 6.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEB07245.1 - 2.6e-16 58.8 1.0 8.7e-16 57.1 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p TGS PF02824.16 EEB07246.1 - 1e-21 76.4 0.0 3.2e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEB07246.1 - 5.5e-20 71.4 0.1 1.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB07246.1 - 2.3e-12 46.4 0.0 4.1e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB07246.1 - 1.2e-05 25.2 0.7 0.0062 16.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EEB07246.1 - 0.0026 16.8 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EEB07246.1 - 0.0074 16.7 0.1 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EEB07246.1 - 0.052 13.5 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEB07246.1 - 0.085 12.5 0.2 0.27 10.9 0.1 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cut12 PF11500.3 EEB07247.1 - 6.5e-14 51.8 1.4 2.8e-13 49.8 1.0 2.1 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Staph_haemo PF05480.6 EEB07247.1 - 0.0031 17.1 0.2 0.88 9.3 0.0 3.3 3 0 0 3 3 3 1 Staphylococcus haemolytic protein zf-ZPR1 PF03367.8 EEB07247.1 - 0.019 14.1 0.2 0.04 13.0 0.1 1.5 1 0 0 1 1 1 0 ZPR1 zinc-finger domain CYSTM PF12734.2 EEB07248.1 - 4.1e-11 42.7 18.0 4.1e-11 42.7 12.5 3.8 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance XPA_C PF05181.7 EEB07249.1 - 8e-27 92.5 1.6 2.6e-26 90.9 1.1 1.9 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EEB07249.1 - 2.5e-08 33.4 5.9 4.1e-08 32.7 4.1 1.4 1 0 0 1 1 1 1 XPA protein N-terminal RNA_pol_Rpb2_4 PF04566.8 EEB07249.1 - 0.032 14.0 0.3 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Vma12 PF11712.3 EEB07249.1 - 4.7 6.9 6.9 1.1 8.9 2.3 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1104 PF06518.6 EEB07249.1 - 5.9 7.0 11.9 2.1 8.5 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Ribosomal_S19e PF01090.14 EEB07250.1 - 8.2e-60 200.2 0.1 9.2e-60 200.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Kinesin PF00225.18 EEB07251.1 - 2.6e-112 374.8 0.0 4.2e-112 374.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Mad3_BUB1_I PF08311.7 EEB07251.1 - 0.036 13.8 0.6 0.11 12.2 0.2 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 AAA_33 PF13671.1 EEB07251.1 - 0.061 13.1 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain VID27 PF08553.5 EEB07252.2 - 2.3e-283 942.2 14.7 4e-283 941.4 10.2 1.4 1 1 0 1 1 1 1 VID27 cytoplasmic protein MARVEL PF01284.18 EEB07253.1 - 3.6e-22 78.7 10.6 4.7e-22 78.3 7.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ndc1_Nup PF09531.5 EEB07253.1 - 0.019 13.4 2.5 0.025 13.0 1.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3311 PF11755.3 EEB07253.1 - 3.7 7.1 9.0 0.11 12.0 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3311) DUF1467 PF07330.7 EEB07253.1 - 5.3 6.9 7.9 23 4.8 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) AAA_25 PF13481.1 EEB07254.1 - 2.5e-05 23.7 0.0 4.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EEB07254.1 - 0.00045 19.9 0.1 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain OS-D PF03392.8 EEB07254.1 - 0.0058 16.5 1.0 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 Insect pheromone-binding family, A10/OS-D HCV_NS4a PF01006.15 EEB07254.1 - 0.0085 15.6 0.1 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 Hepatitis C virus non-structural protein NS4a AAA_19 PF13245.1 EEB07254.1 - 0.051 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EEB07254.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEB07254.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S27e PF01667.12 EEB07255.1 - 4.8e-29 99.6 5.6 6.3e-29 99.2 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EEB07255.1 - 0.0016 18.2 1.2 0.0019 18.0 0.8 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EEB07255.1 - 0.13 11.6 2.9 0.18 11.1 2.0 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_C12 PF01088.16 EEB07256.1 - 1.8e-65 220.1 0.0 2.9e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.20 EEB07257.1 - 1.4e-55 188.2 0.0 1.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07257.1 - 1.5e-36 125.8 0.0 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07257.1 - 1e-08 34.5 0.0 1.4e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEB07257.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EEB07257.1 - 0.21 11.3 0.0 0.48 10.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EEB07258.2 - 8.9e-38 129.9 29.9 8.9e-38 129.9 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB07258.2 - 1.2e-08 33.9 24.5 7.7e-08 31.3 17.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter SPC12 PF06645.8 EEB07258.2 - 1.1 9.0 6.4 1.1 9.1 0.3 2.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Mito_carr PF00153.22 EEB07259.2 - 4e-48 161.0 2.6 8.5e-16 57.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MIS13 PF08202.6 EEB07260.1 - 4.1e-57 193.5 8.2 6.9e-57 192.8 5.7 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family APG6 PF04111.7 EEB07260.1 - 0.17 10.8 6.0 0.35 9.8 4.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-UBR PF02207.15 EEB07261.1 - 4.6e-15 55.0 14.0 4.6e-15 55.0 9.7 3.3 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EEB07261.1 - 0.00021 20.9 9.2 0.00021 20.9 6.4 3.4 3 0 0 3 3 3 1 PHD-finger C1_3 PF07649.7 EEB07261.1 - 0.045 13.7 0.6 0.045 13.7 0.4 4.1 3 1 1 4 4 4 0 C1-like domain MCM PF00493.18 EEB07262.1 - 1.2e-139 464.7 0.0 1.6e-139 464.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EEB07262.1 - 3e-31 108.5 22.7 3e-31 108.5 15.7 2.0 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EEB07262.1 - 3.2e-19 69.5 0.1 2.1e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEB07262.1 - 9.9e-09 34.6 0.0 3e-07 29.8 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEB07262.1 - 1.5e-06 27.9 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEB07262.1 - 0.00065 19.3 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEB07262.1 - 0.0019 17.6 0.1 0.011 15.2 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EEB07262.1 - 0.064 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec23_trunk PF04811.10 EEB07263.1 - 3.6e-67 226.2 0.0 1.6e-66 224.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EEB07263.1 - 1.7e-19 70.1 0.1 3.1e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EEB07263.1 - 7.1e-19 67.1 0.0 1.5e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EEB07263.1 - 1.4e-16 59.7 6.1 2.4e-16 59.0 4.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEB07263.1 - 1.3e-05 24.7 0.0 4.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat DUF2410 PF10307.4 EEB07264.1 - 2.3e-58 196.8 0.0 3.2e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Fig1 PF12351.3 EEB07265.1 - 1.5e-10 41.3 20.7 3.7e-10 39.9 10.7 2.8 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEB07265.1 - 0.1 12.1 24.5 0.72 9.3 17.0 1.9 1 1 0 1 1 1 0 SUR7/PalI family DUF1634 PF07843.6 EEB07265.1 - 0.27 10.8 4.2 0.25 10.9 0.4 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1634) DUF3082 PF11282.3 EEB07265.1 - 0.33 11.0 6.6 0.31 11.1 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) SepZ PF06066.6 EEB07265.1 - 1 9.4 3.3 1.7 8.6 1.2 2.2 2 1 0 2 2 2 0 SepZ WD40 PF00400.27 EEB07266.2 - 4e-21 74.0 21.0 9.9e-07 28.4 0.2 12.0 13 0 0 13 13 13 6 WD domain, G-beta repeat Nup160 PF11715.3 EEB07266.2 - 4.3e-06 25.1 4.0 0.034 12.2 0.1 4.2 3 1 1 4 4 4 3 Nucleoporin Nup120/160 GTP_EFTU PF00009.22 EEB07267.1 - 3.2e-58 196.2 0.1 5.2e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEB07267.1 - 3.3e-30 104.1 0.0 7.4e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EEB07267.1 - 1.3e-29 101.8 0.0 3e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EEB07267.1 - 2.7e-23 81.6 0.0 8.8e-23 79.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEB07267.1 - 8.2e-13 48.2 0.0 3.6e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Sec66 PF09802.4 EEB07268.1 - 5.5e-46 156.3 0.3 6.8e-46 156.0 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4375 PF14300.1 EEB07268.1 - 0.0057 16.6 1.9 0.011 15.7 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4375) PAPS_reduct PF01507.14 EEB07268.1 - 0.15 11.8 1.2 0.21 11.3 0.8 1.1 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF342 PF03961.8 EEB07268.1 - 0.76 8.1 4.9 0.9 7.8 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3847 PF12958.2 EEB07268.1 - 9.1 6.1 10.9 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Tom37_C PF11801.3 EEB07269.1 - 2e-13 50.5 1.3 4.2e-13 49.5 0.0 2.2 2 2 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 EEB07269.1 - 2.6e-13 50.0 0.0 6.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EEB07269.1 - 3.8e-06 27.2 0.1 3.7e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB07269.1 - 2.5e-05 24.0 0.1 0.00022 21.0 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEB07269.1 - 0.083 12.8 0.0 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PAP2 PF01569.16 EEB07270.2 - 4.6e-23 81.3 0.5 1.1e-22 80.0 0.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF1769 PF08588.5 EEB07271.2 - 1.4e-16 60.1 0.3 3e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) WGG PF10273.4 EEB07272.1 - 3.2e-30 104.0 0.9 6.7e-30 103.0 0.6 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EEB07272.1 - 0.0036 17.3 0.4 0.005 16.8 0.3 1.4 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_S17 PF00366.15 EEB07273.1 - 8.4e-18 64.1 2.1 9.5e-18 64.0 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Phage_FRD3 PF05798.6 EEB07273.1 - 0.016 15.4 0.0 0.02 15.2 0.0 1.3 1 1 0 1 1 1 0 Bacteriophage FRD3 protein HD_3 PF13023.1 EEB07273.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 HD domain DMRL_synthase PF00885.14 EEB07274.1 - 5.4e-46 155.8 0.0 6.2e-46 155.6 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Stn1 PF10451.4 EEB07276.1 - 1.4e-08 33.9 0.1 2e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 SAICAR_synt PF01259.13 EEB07277.1 - 6.5e-92 307.1 0.0 7.7e-92 306.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Ras PF00071.17 EEB07279.1 - 4.6e-56 188.6 0.0 5.4e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB07279.1 - 1.7e-17 63.9 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB07279.1 - 1.6e-10 40.5 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB07279.1 - 0.00015 21.2 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEB07279.1 - 0.00029 20.0 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEB07279.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEB07279.1 - 0.0027 16.9 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EEB07279.1 - 0.091 13.0 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter dsDNA_bind PF01984.15 EEB07280.1 - 8e-31 106.2 14.2 9.3e-31 105.9 9.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Arteri_nucleo PF01481.11 EEB07280.1 - 0.029 14.4 1.2 0.029 14.4 0.8 1.7 1 1 1 2 2 2 0 Arterivirus nucleocapsid protein PCI PF01399.22 EEB07280.1 - 0.13 12.5 0.6 0.19 12.0 0.4 1.3 1 0 0 1 1 1 0 PCI domain APC_CDC26 PF10471.4 EEB07280.1 - 0.72 10.6 6.2 0.22 12.2 1.7 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FlgM PF04316.8 EEB07280.1 - 3.2 7.7 7.0 0.56 10.1 0.5 2.8 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Sec2p PF06428.6 EEB07281.1 - 2.3e-22 78.7 6.6 2.3e-22 78.7 4.6 1.9 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Laminin_II PF06009.7 EEB07281.1 - 0.1 12.3 5.6 0.2 11.3 1.0 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.3 EEB07281.1 - 0.28 8.4 17.2 0.38 8.0 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EEB07281.1 - 0.39 9.7 16.4 0.59 9.1 11.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EEB07281.1 - 0.5 8.7 8.6 0.61 8.4 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EEB07281.1 - 0.88 9.3 3.4 0.78 9.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 EEB07281.1 - 1.3 9.0 12.3 5.1 7.1 8.5 1.9 1 1 0 1 1 1 0 DivIVA protein Orbi_VP5 PF00901.12 EEB07281.1 - 1.7 6.7 6.6 2.6 6.1 4.6 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Spc7 PF08317.6 EEB07281.1 - 2 6.9 12.5 2.7 6.5 8.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EEB07281.1 - 2.5 7.6 21.9 6.4 6.3 15.0 1.8 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 EEB07281.1 - 3.5 6.6 5.3 5 6.1 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Enolase_C PF00113.17 EEB07282.2 - 3.3e-227 751.8 2.3 1.1e-121 405.3 0.1 2.1 1 1 1 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEB07282.2 - 6.8e-58 194.2 0.6 1.2e-57 193.4 0.4 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EEB07282.2 - 5.6e-11 42.3 0.1 0.00068 19.5 0.0 3.1 3 0 0 3 3 3 2 Enolase C-terminal domain-like MAAL_C PF07476.6 EEB07282.2 - 1e-06 27.8 0.4 0.026 13.4 0.0 2.4 2 0 0 2 2 2 2 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EEB07282.2 - 2e-06 28.2 0.0 0.14 12.7 0.0 2.9 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF4609 PF15382.1 EEB07282.2 - 0.016 14.8 0.0 5 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) DUF823 PF05689.6 EEB07282.2 - 0.019 14.3 0.0 3.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) Apc5 PF12862.2 EEB07282.2 - 0.044 13.6 0.0 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF1533 PF07550.6 EEB07282.2 - 0.81 9.7 7.6 9.8 6.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) PAP_assoc PF03828.14 EEB07283.1 - 9.9e-17 60.6 0.0 1.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB07283.1 - 4.9e-07 29.9 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HECT PF00632.20 EEB07284.1 - 1.3e-96 323.5 0.2 3.1e-96 322.2 0.1 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EEB07284.1 - 4.7e-91 305.3 5.7 1.6e-85 287.1 0.2 3.1 2 1 1 3 3 3 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EEB07284.1 - 1.1e-57 195.8 9.6 1e-56 192.6 6.6 2.9 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EEB07284.1 - 1e-11 44.6 5.9 1.4e-11 44.2 2.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) Ribosomal_S4 PF00163.14 EEB07285.1 - 9.5e-16 57.9 2.2 9.5e-16 57.9 1.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEB07285.1 - 6e-12 44.7 0.0 1.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ctf8 PF09696.5 EEB07286.1 - 5.8e-15 55.1 0.3 2e-14 53.4 0.2 1.7 1 1 0 1 1 1 1 Ctf8 RAI1 PF08652.6 EEB07287.1 - 2e-25 88.3 0.0 3.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Oxysterol_BP PF01237.13 EEB07288.1 - 2.9e-53 180.6 0.0 2.1e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein eIF3_N PF09440.5 EEB07289.2 - 1.8e-51 173.7 4.3 1.8e-51 173.7 3.0 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EEB07289.2 - 0.00051 20.3 0.4 0.0017 18.6 0.3 2.0 1 0 0 1 1 1 1 PCI domain Ribosomal_60s PF00428.14 EEB07289.2 - 0.087 13.2 8.7 0.034 14.5 3.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein FeoC PF09012.5 EEB07289.2 - 0.13 11.9 0.3 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 FeoC like transcriptional regulator Nop PF01798.13 EEB07290.1 - 4.4e-59 198.0 0.0 7.8e-59 197.2 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEB07290.1 - 6.6e-26 89.8 0.2 1.4e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEB07290.1 - 5.1e-24 84.2 0.3 5.1e-24 84.2 0.2 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EEB07290.1 - 0.42 10.2 24.5 0.8 9.3 17.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cpn60_TCP1 PF00118.19 EEB07291.1 - 5e-148 493.7 0.9 5.7e-148 493.5 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RasGAP PF00616.14 EEB07292.2 - 8.5e-47 159.3 0.0 2e-46 158.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EEB07292.2 - 6.6e-22 77.7 1.5 1.5e-21 76.6 0.5 2.0 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 EEB07292.2 - 0.034 14.4 3.2 4.9 7.5 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) CBS PF00571.23 EEB07293.1 - 2.4e-22 78.4 0.4 6e-06 25.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain zf-RanBP PF00641.13 EEB07294.1 - 2.4e-18 64.9 24.3 9e-09 34.2 1.6 3.7 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EEB07294.1 - 1.6e-08 34.0 0.0 3.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07294.1 - 5.4e-06 26.2 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07294.1 - 0.00028 20.6 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) rRNA_proc-arch PF13234.1 EEB07295.1 - 7.1e-78 261.4 1.0 1.2e-77 260.7 0.7 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EEB07295.1 - 2.8e-57 192.8 0.2 6.2e-57 191.7 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEB07295.1 - 4.7e-22 78.2 0.0 2.9e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07295.1 - 7.7e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB07295.1 - 0.0012 18.7 0.0 0.013 15.3 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EEB07295.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EEB07295.1 - 0.016 15.3 0.0 0.38 10.8 0.0 3.1 3 1 1 4 4 4 0 AAA domain Arch_ATPase PF01637.13 EEB07295.1 - 0.031 13.9 1.3 0.13 11.9 0.0 2.6 3 1 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EEB07295.1 - 0.15 11.8 0.4 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain PAP_assoc PF03828.14 EEB07296.1 - 2.8e-09 36.8 0.1 1.2e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB07296.1 - 8.6e-08 32.4 0.3 3.6e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_central PF04928.12 EEB07296.1 - 4.6e-06 25.6 1.2 0.058 12.1 0.1 3.2 3 0 0 3 3 3 2 Poly(A) polymerase central domain tRNA_NucTransf2 PF09249.6 EEB07296.1 - 0.021 14.7 0.0 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain PadR PF03551.9 EEB07296.1 - 0.028 14.1 0.1 0.1 12.3 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family MarR PF01047.17 EEB07296.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Dynamin_M PF01031.15 EEB07297.2 - 3e-107 357.8 0.9 7.6e-107 356.4 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EEB07297.2 - 1.3e-56 190.9 0.0 2.8e-56 189.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EEB07297.2 - 7.4e-29 99.4 3.8 1.8e-28 98.2 2.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEB07297.2 - 0.0015 18.4 1.5 0.011 15.6 0.2 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEB07297.2 - 0.046 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein UPF0258 PF06789.7 EEB07297.2 - 0.064 13.3 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Strep_SA_rep PF06696.6 EEB07297.2 - 1.2 8.9 3.5 0.44 10.3 0.5 1.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DMAP1 PF05499.7 EEB07298.2 - 2.5e-06 27.1 2.3 0.00018 21.1 1.6 2.3 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.1 EEB07298.2 - 0.012 15.6 0.1 0.054 13.6 0.1 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Atg14 PF10186.4 EEB07298.2 - 0.57 9.0 4.1 1.3 7.8 2.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GCD14 PF08704.5 EEB07299.1 - 3.1e-94 315.0 0.0 3.6e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EEB07299.1 - 4e-05 23.2 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEB07299.1 - 0.00013 21.5 0.0 0.00065 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07299.1 - 0.0013 19.3 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEB07299.1 - 0.0054 15.7 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 EEB07299.1 - 0.051 12.4 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Fibrillarin Methyltransf_26 PF13659.1 EEB07299.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SSFA2_C PF14723.1 EEB07299.1 - 0.16 11.7 1.9 0.28 10.8 1.3 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF3128 PF11326.3 EEB07300.2 - 4.6e-20 71.5 5.9 7.2e-20 70.9 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) IFP_35_N PF07334.8 EEB07300.2 - 0.0022 17.9 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 2 Interferon-induced 35 kDa protein (IFP 35) N-terminus NRN1 PF15056.1 EEB07300.2 - 0.085 12.8 1.7 0.16 11.9 1.1 1.7 1 1 0 1 1 1 0 Neuritin protein family Cmc1 PF08583.5 EEB07300.2 - 0.41 10.4 2.2 16 5.3 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like AlaDh_PNT_N PF05222.10 EEB07301.1 - 9.5e-30 103.3 0.0 1.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EEB07301.1 - 2.5e-15 56.4 0.0 3.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NIF PF03031.13 EEB07302.1 - 1.4e-49 167.7 0.0 1.9e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEB07302.1 - 0.075 13.2 0.4 4.8 7.3 0.0 2.8 2 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase eIF-5_eIF-2B PF01873.12 EEB07303.1 - 2.3e-45 153.2 0.0 3.5e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EEB07303.1 - 2.5e-23 81.7 0.4 2.5e-23 81.7 0.3 2.4 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1754 PF08555.5 EEB07303.1 - 0.039 14.5 0.5 0.039 14.5 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RNA_POL_M_15KD PF02150.11 EEB07303.1 - 0.12 12.0 1.6 0.31 10.7 1.1 1.7 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit PBP1_TM PF14812.1 EEB07303.1 - 5.1 7.4 9.9 21 5.5 0.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med1 PF10744.4 EEB07304.2 - 1.5e-21 76.6 0.0 2.2e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 EEB07305.1 - 1.3e-53 181.8 0.0 2.1e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07305.1 - 1.1e-16 60.6 0.0 3.9e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EEB07305.1 - 0.075 12.5 0.2 0.3 10.6 0.1 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EEB07305.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELL PF10390.4 EEB07306.1 - 7.1e-26 91.0 0.1 7.1e-26 91.0 0.1 3.3 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL TFIIA PF03153.8 EEB07306.1 - 7.7 6.2 23.5 1.6 8.5 13.6 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ORC4_C PF14629.1 EEB07307.1 - 7.7e-38 129.9 2.2 1e-37 129.5 0.1 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EEB07307.1 - 1.3e-16 61.1 0.2 7e-16 58.7 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AT_hook PF02178.14 EEB07307.1 - 2.6e-06 26.4 53.6 0.067 12.8 1.0 5.7 5 0 0 5 5 5 5 AT hook motif AAA_22 PF13401.1 EEB07307.1 - 6.3e-05 23.1 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEB07307.1 - 0.0042 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EEB07307.1 - 0.014 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA12 PF10443.4 EEB07307.1 - 0.019 13.4 0.0 0.033 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.1 EEB07307.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_6 PF00970.19 EEB07308.1 - 3.9e-19 68.5 0.0 6.8e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEB07308.1 - 2.2e-17 63.5 0.0 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEB07308.1 - 0.00031 20.6 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEB07308.1 - 0.053 13.4 0.0 0.36 10.7 0.0 2.3 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain DUF4623 PF15416.1 EEB07308.1 - 0.1 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) FRG1 PF06229.7 EEB07309.2 - 2.9e-18 66.0 0.2 6.2e-18 64.9 0.1 1.5 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EEB07309.2 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Fascin domain Peptidase_M16 PF00675.15 EEB07310.1 - 2.3e-50 170.2 1.3 2.3e-50 170.2 0.9 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEB07310.1 - 2.2e-39 135.0 0.0 1.3e-36 126.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain CybS PF05328.7 EEB07311.1 - 3e-46 156.3 0.0 3.5e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 CybS PIG-P PF08510.7 EEB07311.1 - 0.00056 19.5 0.3 0.00079 19.0 0.2 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 EEB07311.1 - 0.071 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) E1-E2_ATPase PF00122.15 EEB07312.1 - 1.1e-47 162.0 1.3 1.2e-47 161.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEB07312.1 - 7.4e-39 134.3 0.1 1.3e-38 133.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB07312.1 - 5.8e-11 42.9 0.0 1.1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEB07312.1 - 7.1e-10 38.8 0.3 4.4e-08 33.1 0.0 3.0 3 0 0 3 3 3 1 Heavy-metal-associated domain PRA-CH PF01502.13 EEB07313.1 - 5.4e-25 86.8 0.7 1.2e-24 85.6 0.5 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EEB07313.1 - 1.9e-13 50.4 0.1 5e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EEB07313.1 - 0.0014 18.5 0.3 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain DUF2683 PF10884.3 EEB07313.1 - 0.027 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) Amino_oxidase PF01593.19 EEB07314.2 - 2.2e-25 89.6 0.1 2.1e-24 86.4 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EEB07314.2 - 8e-10 38.7 0.0 2.9e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.1 EEB07314.2 - 2.4e-08 33.8 0.0 1.2e-07 31.6 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EEB07314.2 - 6.7e-06 26.2 1.1 6.7e-06 26.2 0.8 2.9 3 0 0 3 3 3 1 HMG (high mobility group) box DAO PF01266.19 EEB07314.2 - 0.00033 19.6 0.0 0.0077 15.1 0.0 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEB07314.2 - 0.00044 20.0 0.4 2.5 7.8 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEB07314.2 - 0.0018 18.3 0.6 0.37 10.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEB07314.2 - 0.0084 16.0 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Cyclin_N PF00134.18 EEB07317.1 - 2.1e-36 124.3 1.0 3.7e-36 123.4 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB07317.1 - 1.6e-06 28.0 0.3 1.7e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Acid_PPase PF12689.2 EEB07318.2 - 1.4e-55 187.4 0.0 1.6e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EEB07318.2 - 0.00012 21.7 0.1 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEB07318.2 - 0.021 15.0 1.0 0.18 12.0 0.0 2.6 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB07318.2 - 0.12 12.7 0.2 0.82 10.0 0.0 1.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 EEB07319.1 - 2.9e-08 33.4 10.4 6.8e-08 32.2 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEB07319.1 - 6.8e-08 31.6 1.5 1.5e-07 30.6 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chorismate_bind PF00425.13 EEB07322.1 - 1.7e-72 243.8 0.0 2.5e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EEB07322.1 - 4.7e-34 117.5 0.0 7e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EEB07322.1 - 7e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EEB07322.1 - 9.5e-07 28.4 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Carb_kinase PF01256.12 EEB07322.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Stc1 PF12898.2 EEB07323.1 - 4e-21 74.8 12.6 4e-21 74.8 8.7 2.0 2 0 0 2 2 2 1 Stc1 domain Ebola_NP PF05505.7 EEB07323.1 - 0.031 12.3 16.1 0.041 11.9 11.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3295 PF11702.3 EEB07323.1 - 0.077 11.9 15.3 0.098 11.6 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4407 PF14362.1 EEB07323.1 - 1.7 7.5 5.4 2.2 7.1 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CW PF07496.10 EEB07323.1 - 3 7.6 7.4 0.86 9.3 1.0 2.5 2 0 0 2 2 2 0 CW-type Zinc Finger DUF3474 PF11960.3 EEB07323.1 - 3 7.8 7.3 0.5 10.3 2.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3474) PHD PF00628.24 EEB07323.1 - 8.9 6.0 10.4 8.5 6.1 1.6 3.2 3 0 0 3 3 3 0 PHD-finger HECT PF00632.20 EEB07324.2 - 2.2e-47 161.7 0.3 2.5e-46 158.3 0.0 2.6 3 1 0 3 3 3 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.7 EEB07324.2 - 2.2 7.9 12.2 26 4.5 0.0 2.5 2 0 0 2 2 2 0 LSD1 zinc finger Pro_isomerase PF00160.16 EEB07326.2 - 1.5e-47 161.6 0.1 1.8e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DIM PF08194.7 EEB07326.2 - 0.0074 16.2 0.8 0.15 12.0 0.2 2.2 2 0 0 2 2 2 1 DIM protein Atg8 PF02991.11 EEB07327.1 - 1.9e-50 169.1 0.2 2.2e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEB07327.1 - 3.7e-07 30.2 0.0 4.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HopW1-1 PF15457.1 EEB07328.2 - 0.047 12.7 2.5 0.088 11.8 1.7 1.4 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA zf-C3HC4_2 PF13923.1 EEB07328.2 - 0.21 11.6 1.4 0.4 10.7 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 EEB07328.2 - 2.3 8.4 5.0 39 4.4 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SPT16 PF08644.6 EEB07329.1 - 1.6e-56 190.3 0.1 6.3e-56 188.4 0.1 2.1 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EEB07329.1 - 1.5e-53 180.7 0.2 3.2e-53 179.5 0.1 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EEB07329.1 - 4.2e-25 88.5 0.0 8.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EEB07329.1 - 3.8e-23 81.2 0.3 1.1e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like VirK PF06903.7 EEB07329.1 - 0.037 13.7 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 VirK protein ig PF00047.20 EEB07329.1 - 0.09 12.9 0.2 1 9.5 0.1 2.5 1 1 0 1 1 1 0 Immunoglobulin domain Adeno_E1B_19K PF01691.11 EEB07329.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Nol1_Nop2_Fmu PF01189.12 EEB07330.1 - 3.8e-99 331.6 0.0 5.4e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EEB07330.1 - 0.00015 21.4 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EEB07330.1 - 0.061 13.9 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF4107 PF13389.1 EEB07330.1 - 0.13 11.9 1.6 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) ER_lumen_recept PF00810.13 EEB07331.1 - 8.4e-52 175.5 9.1 1.1e-51 175.1 6.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EEB07331.1 - 8.5e-06 25.2 3.9 0.0082 15.6 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat UCH PF00443.24 EEB07332.1 - 6.7e-51 172.9 0.0 9.1e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB07332.1 - 7.1e-09 35.5 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Phos_pyr_kin PF08543.7 EEB07333.2 - 2.8e-79 265.7 0.2 3.9e-79 265.3 0.1 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EEB07333.2 - 1.6e-50 171.8 0.2 2.2e-50 171.3 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 EEB07333.2 - 8.4e-05 21.8 0.1 0.0003 20.0 0.0 2.0 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.19 EEB07333.2 - 0.0099 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase BsuPI PF12690.2 EEB07333.2 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Phos_pyr_kin PF08543.7 EEB07334.1 - 3.7e-75 252.3 0.9 5.9e-75 251.6 0.6 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EEB07334.1 - 3.8e-27 95.4 0.3 5.2e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EEB07334.1 - 0.0014 17.8 0.1 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HNH_4 PF13395.1 EEB07334.1 - 0.096 12.3 0.1 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease HTH_28 PF13518.1 EEB07334.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain GDI PF00996.13 EEB07335.1 - 3e-216 717.8 0.0 3.4e-216 717.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Hormone_2 PF00123.15 EEB07335.1 - 0.12 12.2 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Peptide hormone WD40 PF00400.27 EEB07336.1 - 1.1e-36 123.3 9.2 7.2e-09 35.2 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat NTF2 PF02136.15 EEB07337.1 - 2.5e-35 121.3 0.9 2.8e-35 121.2 0.6 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 EEB07337.1 - 0.049 13.5 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4518 PF15008.1 EEB07337.1 - 0.061 12.3 0.3 0.097 11.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DUF3089 PF11288.3 EEB07337.1 - 0.093 11.8 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF4440 PF14534.1 EEB07337.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Pkinase PF00069.20 EEB07338.2 - 3.5e-70 236.1 0.0 4.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07338.2 - 6.2e-30 104.1 0.0 8.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEB07338.2 - 6.3e-10 39.4 6.5 2.7e-09 37.4 4.5 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB07338.2 - 3.9e-08 32.6 0.0 6.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EEB07338.2 - 0.0011 18.7 0.0 0.36 10.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EEB07338.2 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEB07338.2 - 0.076 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Brix PF04427.13 EEB07339.1 - 3.1e-55 186.8 0.1 4.1e-55 186.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Baculo_PP31 PF05311.6 EEB07339.1 - 0.087 12.0 3.8 0.15 11.2 2.6 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_S49_N PF08496.5 EEB07339.1 - 2.2 8.0 6.6 4.3 7.0 4.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal tRNA-synt_1 PF00133.17 EEB07340.1 - 6.9e-147 490.0 0.0 1.7e-145 485.4 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEB07340.1 - 9.2e-19 67.3 2.5 4.3e-10 38.8 0.0 4.1 3 2 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEB07340.1 - 3.2e-16 59.4 0.0 7.4e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 EEB07340.1 - 1.1e-05 24.8 0.1 0.0019 17.5 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EEB07340.1 - 8.3e-05 21.8 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EEB07340.1 - 0.00018 20.4 0.1 0.011 14.5 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EEB07340.1 - 0.003 16.7 0.1 0.025 13.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 EEB07340.1 - 0.0037 15.9 0.0 1.8 7.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (K) DAGK_cat PF00781.19 EEB07341.2 - 6.1e-23 80.6 0.0 1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EEB07341.2 - 0.014 14.2 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Abhydrolase_3 PF07859.8 EEB07342.1 - 9.5e-28 97.2 0.0 1.7e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EEB07342.1 - 2.1e-12 46.4 0.0 2.1e-09 36.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EEB07342.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB07342.1 - 0.00058 19.6 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEB07342.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 EEB07342.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Myosin_head PF00063.16 EEB07343.1 - 1e-240 800.5 4.7 2.1e-240 799.4 3.2 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) PRK PF00485.13 EEB07343.1 - 0.0086 15.6 1.0 1.5 8.3 0.1 3.8 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EEB07343.1 - 0.0092 16.1 5.3 0.21 11.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EEB07343.1 - 0.036 13.8 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain DUF948 PF06103.6 EEB07343.1 - 0.12 12.2 30.2 0.46 10.3 0.9 7.0 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_S8 PF00082.17 EEB07344.1 - 4.1e-60 203.3 6.4 5.7e-60 202.8 4.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEB07344.1 - 2.8e-13 50.2 0.2 5.4e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 PP2C PF00481.16 EEB07345.1 - 9e-42 143.2 0.0 1.2e-40 139.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEB07345.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEB07345.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) UPF0047 PF01894.12 EEB07346.2 - 1e-41 141.4 0.0 1.3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Alpha-amylase PF00128.19 EEB07347.1 - 5.7e-64 216.4 0.0 7.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEB07347.1 - 1.4e-13 50.6 0.2 1.5e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EEB07347.1 - 0.025 13.4 0.1 0.064 12.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase like GH101 IMS PF00817.15 EEB07347.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family WD40 PF00400.27 EEB07348.1 - 2e-53 176.4 9.3 1.6e-11 43.5 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEB07348.1 - 2.5e-06 27.3 0.0 0.011 15.4 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EEB07348.1 - 0.00014 21.5 0.0 0.2 11.4 0.0 3.5 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 EEB07348.1 - 0.0014 18.1 0.1 0.026 14.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEB07348.1 - 0.0032 15.3 0.7 0.06 11.1 0.2 2.1 2 0 0 2 2 2 2 IKI3 family Nup160 PF11715.3 EEB07348.1 - 0.0048 15.1 0.0 0.028 12.5 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 DUF1620 PF07774.8 EEB07349.1 - 1.5e-61 207.4 0.1 2.4e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EEB07349.1 - 0.003 17.0 1.1 0.91 8.9 0.1 3.7 3 2 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EEB07349.1 - 0.049 13.1 0.0 50 3.6 0.0 3.9 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1515 PF07439.6 EEB07350.1 - 0.036 13.8 0.2 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CAF1C_H4-bd PF12265.3 EEB07351.1 - 6.7e-20 70.7 0.1 1.8e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EEB07351.1 - 4.3e-13 48.5 7.9 0.0092 15.8 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1183 PF06682.7 EEB07352.1 - 0.087 12.4 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1649 PF07855.7 EEB07353.1 - 9.3e-24 83.9 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) JmjC PF02373.17 EEB07354.1 - 2.8e-18 66.2 0.0 6.1e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EEB07354.1 - 1.8e-14 53.8 0.0 3.5e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Avl9 PF09794.4 EEB07356.1 - 8.8e-117 389.7 0.0 1.1e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EEB07356.1 - 1.5e-06 27.7 0.0 0.00034 19.9 0.0 2.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EEB07356.1 - 3e-06 26.9 0.0 0.00055 19.6 0.0 2.4 1 1 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EEB07356.1 - 0.0045 17.0 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking G-alpha PF00503.15 EEB07357.1 - 4.3e-105 351.6 2.7 5e-105 351.3 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEB07357.1 - 3e-14 52.6 0.3 8.8e-10 38.0 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB07357.1 - 0.00019 20.6 3.7 0.017 14.3 0.2 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEB07357.1 - 0.0049 17.3 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EEB07357.1 - 0.0052 16.2 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEB07357.1 - 0.025 14.5 0.0 0.39 10.7 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EEB07357.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mit_KHE1 PF10173.4 EEB07358.1 - 5.6e-48 163.2 0.3 6.7e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related SKN1 PF03935.10 EEB07359.2 - 7.2e-200 664.4 0.7 1e-199 663.9 0.5 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SWIRM PF04433.12 EEB07360.1 - 1.2e-32 111.8 0.0 3e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EEB07360.1 - 8.1e-09 35.4 0.1 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB07360.1 - 7.8e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EEB07360.1 - 0.034 13.6 6.5 0.06 12.9 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Chordopox_RPO7 PF05864.7 EEB07360.1 - 0.4 10.8 2.2 3.6 7.7 0.2 2.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Beta_elim_lyase PF01212.16 EEB07361.1 - 4.5e-82 275.4 0.0 5.9e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEB07361.1 - 0.00027 20.0 0.0 0.00045 19.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEB07361.1 - 0.0014 17.0 0.0 0.0023 16.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEB07361.1 - 0.0054 15.5 0.0 0.0073 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.27 EEB07362.1 - 6.9e-12 44.7 8.7 0.00063 19.5 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEB07362.1 - 0.053 13.2 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_S14 PF00253.16 EEB07363.2 - 4.6e-16 57.9 0.0 8.3e-16 57.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Adaptin_N PF01602.15 EEB07364.1 - 3.4e-88 296.2 13.4 4.3e-88 295.9 9.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEB07364.1 - 1.4e-11 44.4 3.4 5.1e-06 26.6 0.1 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EEB07364.1 - 7.3e-07 28.7 5.8 0.57 10.4 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.2 EEB07364.1 - 6e-05 22.1 1.0 0.00026 20.0 0.2 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 EEB07364.1 - 0.013 16.0 6.0 12 6.5 0.4 5.2 4 1 1 5 5 5 0 HEAT-like repeat Cohesin_HEAT PF12765.2 EEB07364.1 - 0.041 13.8 1.1 0.68 9.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.7 EEB07364.1 - 0.05 11.5 5.8 0.097 10.5 4.1 1.5 1 0 0 1 1 1 0 Nop14-like family TPR_9 PF13371.1 EEB07364.1 - 0.14 12.0 1.2 5.8 6.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Prp18 PF02840.10 EEB07365.1 - 7.9e-48 161.9 0.1 7.9e-48 161.9 0.1 2.7 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EEB07365.1 - 4.1e-05 22.7 0.0 0.00015 20.9 0.0 2.0 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like KH_5 PF13184.1 EEB07365.1 - 0.029 14.1 1.3 0.086 12.6 0.8 1.8 1 1 0 1 1 1 0 NusA-like KH domain Oxysterol_BP PF01237.13 EEB07365.1 - 4 5.8 18.6 0.13 10.7 8.6 1.6 2 0 0 2 2 2 0 Oxysterol-binding protein SRP19 PF01922.12 EEB07366.1 - 3.1e-21 75.7 0.0 4.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein ABC_membrane PF00664.18 EEB07367.2 - 2.4e-29 102.5 9.7 3.4e-29 102.1 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEB07367.2 - 8.9e-17 61.6 0.0 2.7e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EEB07367.2 - 0.00013 21.2 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EEB07367.2 - 0.0046 16.8 0.2 0.063 13.1 0.2 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TFIID_20kDa PF03847.8 EEB07368.2 - 5.5e-35 119.4 5.8 3.9e-34 116.7 0.9 2.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EEB07368.2 - 5.5e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB07368.2 - 0.00031 20.7 0.0 0.00075 19.5 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EEB07368.2 - 0.0029 17.3 0.0 0.011 15.4 0.0 2.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF4404 PF14357.1 EEB07368.2 - 2.5 8.5 15.4 0.8 10.1 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) zf-CCCH PF00642.19 EEB07369.2 - 0.0023 17.5 0.7 0.0023 17.5 0.5 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SOG2 PF10428.4 EEB07369.2 - 3.4 6.2 15.5 4.7 5.7 10.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SNF2_N PF00176.18 EEB07370.2 - 5.5e-68 228.9 0.0 4.1e-67 226.0 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EEB07370.2 - 1.2e-44 152.4 12.7 9.2e-44 149.5 9.3 2.0 2 1 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EEB07370.2 - 2.7e-14 52.7 0.0 6.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEB07370.2 - 5.2e-06 25.4 0.0 2.4e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EEB07370.2 - 1e-05 25.1 0.0 0.0005 19.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB07370.2 - 1.6e-05 25.0 0.1 0.04 14.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain Gp_dh_N PF00044.19 EEB07370.2 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain zf-ZPR1 PF03367.8 EEB07371.1 - 3.2e-118 390.5 1.8 9.3e-59 197.1 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EEB07371.1 - 0.21 11.2 7.6 0.44 10.2 0.2 2.7 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Terminase_GpA PF05876.7 EEB07371.1 - 0.27 9.5 3.3 1.3 7.2 0.1 2.5 2 1 1 3 3 3 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 EEB07371.1 - 0.69 10.2 5.4 26 5.2 0.0 3.1 3 0 0 3 3 3 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EEB07371.1 - 0.83 9.3 4.4 19 5.0 0.4 3.2 3 1 0 3 3 3 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 EEB07371.1 - 1.3 8.7 7.2 1.5 8.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EEB07371.1 - 1.5 8.0 8.0 3.6 6.9 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEB07371.1 - 5.7 6.7 11.7 4.3 7.0 0.1 4.2 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEB07371.1 - 6.2 6.5 11.9 4.8 6.8 0.1 4.1 4 1 0 4 4 4 0 zinc-ribbon domain YjeF_N PF03853.10 EEB07372.2 - 1.6e-37 128.7 0.0 1.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Sulfate_transp PF00916.15 EEB07373.1 - 1e-82 277.3 6.0 2e-82 276.3 4.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEB07373.1 - 4.7e-32 109.4 3.2 4.7e-32 109.4 2.2 3.0 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEB07373.1 - 7.2e-13 47.9 0.0 1.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EEB07373.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 STAS domain Transket_pyr PF02779.19 EEB07374.1 - 3.5e-63 212.3 0.0 7.7e-63 211.1 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EEB07374.1 - 4.6e-58 196.3 0.0 7.9e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component CENP-X PF09415.5 EEB07375.1 - 1.1e-21 76.4 0.1 1.2e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X BCNT PF07572.7 EEB07376.1 - 1.9e-19 69.3 2.4 5.3e-19 67.9 1.7 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUSP PF06337.7 EEB07376.1 - 0.96 9.8 5.0 0.77 10.2 0.6 2.3 2 1 0 2 2 2 0 DUSP domain TEX19 PF15553.1 EEB07376.1 - 1 9.2 7.0 1.9 8.2 4.8 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 MCPVI PF02993.9 EEB07376.1 - 2.3 8.3 9.0 3 7.9 6.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI TP_methylase PF00590.15 EEB07377.1 - 1.4e-21 77.1 0.1 2.3e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.20 EEB07378.1 - 1.6e-67 227.3 0.0 2.1e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07378.1 - 1.1e-33 116.4 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EEB07378.1 - 8.7e-08 32.0 0.0 2.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 PH domain APH PF01636.18 EEB07378.1 - 3.4e-05 23.6 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB07378.1 - 3.6e-05 22.8 0.0 0.0001 21.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEB07378.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.24 EEB07378.1 - 0.011 15.9 0.4 0.029 14.5 0.0 1.9 2 0 0 2 2 2 0 PH domain YrbL-PhoP_reg PF10707.4 EEB07378.1 - 0.012 15.0 1.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EEB07378.1 - 0.017 14.4 0.1 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EEB07378.1 - 0.029 13.9 0.2 0.068 12.7 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EEB07378.1 - 0.032 13.0 0.1 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EEB07378.1 - 0.038 12.7 0.2 0.038 12.7 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF3454 PF11936.3 EEB07378.1 - 0.76 10.0 15.2 4.5 7.5 2.1 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3454) LSM PF01423.17 EEB07379.1 - 3.4e-15 55.3 0.4 4.2e-15 55.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB07379.1 - 0.0096 15.8 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DASH_Spc34 PF08657.5 EEB07380.1 - 7.8e-17 61.7 12.6 1.8e-08 34.3 3.3 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Bacillus_HBL PF05791.6 EEB07380.1 - 0.0029 16.9 0.9 0.0041 16.5 0.4 1.4 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) EspA PF03433.8 EEB07380.1 - 0.006 16.0 0.1 0.0097 15.3 0.1 1.3 1 0 0 1 1 1 1 EspA-like secreted protein FTA4 PF13093.1 EEB07380.1 - 3 7.2 6.4 3.9 6.8 4.5 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin_2 PF01920.15 EEB07380.1 - 3.1 7.6 7.1 66 3.3 4.4 2.6 2 1 0 2 2 2 0 Prefoldin subunit DUF2229 PF09989.4 EEB07381.1 - 1.3 8.4 4.7 1.5 8.1 1.6 1.8 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Metal_resist PF13801.1 EEB07381.1 - 1.4 8.8 8.6 2.6 8.0 5.9 1.4 1 0 0 1 1 1 0 Heavy-metal resistance FlxA PF14282.1 EEB07381.1 - 6 6.8 15.1 22 5.0 10.4 2.1 1 1 0 1 1 1 0 FlxA-like protein KfrA_N PF11740.3 EEB07381.1 - 6.4 7.2 12.5 0.32 11.4 3.6 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term TLD PF07534.11 EEB07382.1 - 6.8e-24 84.4 0.0 8.4e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 TLD W2 PF02020.13 EEB07383.1 - 9.2e-16 57.5 0.1 9.2e-16 57.5 0.1 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EEB07383.1 - 3.5e-14 51.5 23.7 9.9e-06 24.8 6.8 4.5 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EEB07383.1 - 8.1e-09 35.1 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EEB07383.1 - 1.2e-07 31.1 23.6 7.1e-05 22.2 1.3 4.1 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EEB07383.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 EEB07383.1 - 0.12 10.9 4.5 2.3 6.6 0.3 2.3 1 1 1 2 2 2 0 L-fucokinase HSF_DNA-bind PF00447.12 EEB07384.2 - 5.3e-32 110.0 0.7 3.3e-23 81.8 0.2 2.7 2 0 0 2 2 2 2 HSF-type DNA-binding Response_reg PF00072.19 EEB07384.2 - 3.4e-20 72.1 0.2 9.4e-20 70.7 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Mito_carr PF00153.22 EEB07385.1 - 8.3e-65 214.5 5.9 4.9e-23 80.6 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein BolA PF01722.13 EEB07387.2 - 6.8e-21 74.0 0.0 8e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein RRP14 PF15459.1 EEB07388.1 - 5.5e-16 58.3 3.4 5.5e-16 58.3 2.4 2.5 2 1 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 HLH PF00010.21 EEB07388.1 - 0.18 11.5 5.3 3 7.5 3.7 2.6 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF87 PF01935.12 EEB07388.1 - 0.42 10.4 4.4 0.52 10.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 SRP-alpha_N PF04086.8 EEB07388.1 - 0.77 9.0 19.3 0.86 8.9 13.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Draxin PF15550.1 EEB07388.1 - 2.8 7.4 11.5 3.3 7.2 8.0 1.0 1 0 0 1 1 1 0 Draxin Ribosomal_S7 PF00177.16 EEB07391.1 - 4.7e-40 136.5 0.8 5.9e-40 136.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SUN PF03856.8 EEB07392.1 - 1.8e-76 256.7 13.8 2.7e-76 256.1 9.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_S2 PF00318.15 EEB07393.1 - 4.2e-43 147.0 0.1 1e-21 77.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 COX14 PF14880.1 EEB07394.1 - 1.3e-06 27.9 0.1 2.2e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly PDEase_II PF02112.10 EEB07395.2 - 1.4e-69 234.6 5.6 2.1e-64 217.5 3.0 2.1 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EEB07395.2 - 0.023 14.2 2.3 0.048 13.1 1.6 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF4528 PF15031.1 EEB07395.2 - 0.074 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Clat_adaptor_s PF01217.15 EEB07396.2 - 4.2e-11 42.7 0.1 6.9e-11 42.0 0.1 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain CENP_C_N PF15622.1 EEB07396.2 - 0.0059 15.8 1.4 0.0072 15.6 1.0 1.2 1 0 0 1 1 1 1 Kinetochore assembly subunit CENP-C N-terminal Trp_repressor PF01371.14 EEB07396.2 - 0.038 13.9 0.2 0.15 11.9 0.2 2.1 2 1 1 3 3 3 0 Trp repressor protein DUF2420 PF10336.4 EEB07397.1 - 1.3e-21 76.3 0.1 2.3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mito_carr PF00153.22 EEB07398.1 - 1.4e-69 229.8 1.6 2e-22 78.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Kinetochor_Ybp2 PF08568.5 EEB07399.1 - 7.5e-30 103.7 11.2 3e-18 65.4 3.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin RasGEF PF00617.14 EEB07400.1 - 5.6e-48 163.1 0.2 2.1e-47 161.2 0.1 2.1 1 0 0 1 1 1 1 RasGEF domain SH3_2 PF07653.12 EEB07400.1 - 6.9e-09 35.0 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEB07400.1 - 1.7e-07 30.7 0.0 3.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEB07400.1 - 2.2e-07 30.1 0.0 4.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.15 EEB07400.1 - 7.4e-07 29.2 2.4 7.4e-07 29.2 1.7 2.7 2 1 0 2 2 2 1 RasGEF N-terminal motif DUF3336 PF11815.3 EEB07401.1 - 7.6e-35 119.5 0.9 1.2e-34 118.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEB07401.1 - 1.4e-13 51.2 0.1 2.8e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PIG-F PF06699.6 EEB07402.1 - 4.1e-44 150.8 12.1 7.7e-44 149.9 8.4 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F adh_short PF00106.20 EEB07402.1 - 7.4e-26 91.0 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB07402.1 - 5.7e-13 48.9 0.0 9.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB07402.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEB07402.1 - 2.2e-06 27.3 0.0 8.9e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB07402.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EEB07402.1 - 0.00073 18.7 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EEB07402.1 - 0.0027 16.7 0.2 0.0069 15.4 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EEB07402.1 - 0.13 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ERO1 PF04137.10 EEB07403.1 - 8.8e-112 373.6 0.3 1.2e-111 373.2 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3447 PF11929.3 EEB07403.1 - 0.52 10.1 4.4 6.6 6.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) RasGEF_N PF00618.15 EEB07404.1 - 0.016 15.2 1.8 0.16 12.0 0.2 2.5 2 1 0 2 2 2 0 RasGEF N-terminal motif ERO1 PF04137.10 EEB07404.1 - 0.017 14.1 0.7 0.017 14.1 0.5 2.1 2 1 1 3 3 3 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PaaSYMP PF14738.1 EEB07404.1 - 0.03 14.0 2.7 0.048 13.3 1.9 1.3 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Mei4 PF13971.1 EEB07404.1 - 0.21 10.4 5.9 2.7 6.8 4.1 2.3 1 1 0 1 1 1 0 Meiosis-specific protein Mei4 Lum_binding PF00677.12 EEB07405.1 - 3.3e-44 148.6 2.2 3.2e-22 78.1 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF3818 PF12825.2 EEB07406.1 - 1.9e-110 368.7 1.7 3e-110 368.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EEB07406.1 - 3.1e-34 117.5 1.4 1e-33 115.8 0.9 2.0 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EEB07406.1 - 1.6e-09 37.5 0.6 4.4e-09 36.1 0.4 1.8 1 0 0 1 1 1 1 PX domain EF1_GNE PF00736.14 EEB07407.1 - 3.5e-31 106.7 2.3 3.5e-31 106.7 1.6 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EEB07407.1 - 2.1e-13 50.1 3.4 8e-13 48.2 2.3 2.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EEB07407.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB07407.1 - 0.0055 16.5 0.2 0.02 14.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Rox3 PF08633.5 EEB07408.1 - 3.8e-13 50.1 0.3 8.2e-13 49.0 0.1 1.6 1 1 0 2 2 2 1 Rox3 mediator complex subunit Glutaredoxin PF00462.19 EEB07409.1 - 1.1e-13 50.9 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF929 PF06053.6 EEB07409.1 - 0.051 12.6 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) GST_N_3 PF13417.1 EEB07409.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 EEB07409.1 - 0.15 12.2 0.0 0.64 10.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DAO PF01266.19 EEB07410.1 - 6.1e-23 81.3 0.8 1.4e-22 80.1 0.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEB07410.1 - 0.00081 19.7 0.5 0.0018 18.6 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEB07410.1 - 0.0014 17.7 0.5 0.0029 16.7 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEB07410.1 - 0.0018 17.4 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EEB07410.1 - 0.0045 17.0 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB07410.1 - 0.019 14.9 0.4 0.041 13.8 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEB07410.1 - 0.035 12.9 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EEB07410.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEB07410.1 - 0.15 10.9 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEB07410.1 - 0.16 10.8 0.1 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Fe_hyd_lg_C PF02906.9 EEB07411.1 - 1.7e-71 240.8 0.0 2.3e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.20 EEB07412.1 - 8e-62 208.7 0.0 2.7e-39 134.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07412.1 - 3.9e-25 88.3 0.0 1.2e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEB07412.1 - 5.2e-07 28.9 0.0 0.00019 20.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEB07412.1 - 0.00013 21.8 0.0 0.0068 16.1 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Response_reg PF00072.19 EEB07412.1 - 0.00044 20.2 0.0 0.00099 19.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kdo PF06293.9 EEB07412.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EEB07412.1 - 0.059 12.1 0.2 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Utp12 PF04003.7 EEB07413.1 - 2e-09 37.3 0.2 2.7e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SGT1 PF07093.6 EEB07413.1 - 0.00018 20.0 12.2 0.00018 20.0 8.5 1.1 1 0 0 1 1 1 1 SGT1 protein Rif1_N PF12231.3 EEB07413.1 - 0.099 11.5 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Hid1 PF12722.2 EEB07413.1 - 2.7 5.5 9.7 3.3 5.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.5 EEB07413.1 - 3.7 6.5 27.6 6 5.8 19.1 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EEB07413.1 - 6.9 5.0 27.1 9.4 4.5 18.8 1.1 1 0 0 1 1 1 0 Daxx Family Bromodomain PF00439.20 EEB07414.2 - 7.6e-53 176.3 0.1 1.3e-26 92.3 0.1 2.5 2 0 0 2 2 2 2 Bromodomain ABC_tran_2 PF12848.2 EEB07414.2 - 1.7 8.5 7.2 5.3 6.9 0.2 2.7 2 0 0 2 2 2 0 ABC transporter ApoO PF09769.4 EEB07415.1 - 3.1e-25 88.7 0.2 1.1e-24 86.9 0.0 1.7 1 1 1 2 2 2 1 Apolipoprotein O HSP9_HSP12 PF04119.7 EEB07415.1 - 0.071 13.2 0.3 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 YtxH PF12732.2 EEB07415.1 - 0.46 10.8 1.6 0.95 9.8 0.5 1.8 2 0 0 2 2 2 0 YtxH-like protein Proteasome PF00227.21 EEB07416.1 - 1e-59 201.0 0.1 1.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB07416.1 - 1.6e-10 40.0 0.3 4.9e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WLM PF08325.5 EEB07417.1 - 2.3e-36 125.4 0.8 7.1e-36 123.8 0.5 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EEB07417.1 - 0.00028 20.7 2.2 0.00049 19.9 0.9 1.8 1 1 1 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.18 EEB07417.1 - 0.00043 19.6 0.0 0.00096 18.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_MA_2 PF13485.1 EEB07417.1 - 0.0077 16.2 0.2 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Cu_amine_oxidN2 PF02727.11 EEB07417.1 - 0.1 12.6 0.1 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain COX6B PF02297.12 EEB07418.1 - 3e-20 72.0 6.9 3.6e-20 71.7 4.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EEB07418.1 - 0.0014 18.5 0.8 0.0031 17.3 0.5 1.7 1 1 0 1 1 1 1 CHCH domain UCR_hinge PF02320.11 EEB07418.1 - 0.16 11.9 1.3 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EEB07418.1 - 2.8 7.8 7.4 16 5.4 5.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Chorismate_bind PF00425.13 EEB07419.1 - 7.7e-91 303.9 0.0 1.6e-90 302.9 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EEB07419.1 - 6.5e-27 94.2 0.2 6.1e-25 87.8 0.0 3.2 4 0 0 4 4 4 1 Anthranilate synthase component I, N terminal region RNA_pol_A_bac PF01000.21 EEB07420.1 - 3.1e-32 111.0 0.0 5.7e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEB07420.1 - 4.2e-16 57.8 0.0 5.4e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EEB07420.1 - 0.067 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF22 L51_S25_CI-B8 PF05047.11 EEB07421.1 - 2.9e-06 26.8 0.1 5.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EF_TS PF00889.14 EEB07422.1 - 7.5e-21 74.4 0.0 8.6e-20 71.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor TS DUF303 PF03629.13 EEB07422.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF303) Brix PF04427.13 EEB07423.1 - 2e-42 145.0 0.7 2.5e-42 144.6 0.5 1.1 1 0 0 1 1 1 1 Brix domain Dicty_REP PF05086.7 EEB07423.1 - 0.0041 14.9 0.2 0.0059 14.4 0.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Tubulin PF00091.20 EEB07424.1 - 5e-70 235.6 0.0 6.9e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEB07424.1 - 5.8e-49 165.3 0.0 9.5e-49 164.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEB07424.1 - 0.002 17.6 0.0 0.0049 16.3 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L37ae PF01780.14 EEB07425.1 - 2.3e-37 126.7 8.7 2.6e-37 126.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEB07425.1 - 0.0012 18.1 2.7 0.012 15.0 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EEB07425.1 - 0.009 16.2 0.5 0.043 14.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 EEB07425.1 - 0.017 14.9 4.1 0.027 14.2 2.8 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Saf-Nte_pilin PF09460.5 EEB07425.1 - 0.026 14.3 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Saf-pilin pilus formation protein zf-ribbon_3 PF13248.1 EEB07425.1 - 0.047 12.8 0.5 2 7.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EEB07425.1 - 0.05 13.4 0.5 0.098 12.4 0.4 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Terminase_GpA PF05876.7 EEB07425.1 - 0.064 11.6 0.5 0.067 11.5 0.3 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_2 PF13240.1 EEB07425.1 - 0.075 12.5 1.3 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EEB07425.1 - 0.12 11.9 0.5 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Sgf11 PF08209.6 EEB07425.1 - 0.14 11.4 3.9 6.5 6.1 0.8 2.4 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EEB07425.1 - 0.16 11.6 0.6 0.16 11.6 0.4 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EEB07425.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 EEB07425.1 - 2.4 8.6 6.2 1.9 8.9 0.3 2.5 3 0 0 3 3 2 0 Zinc finger, C2H2 type EF-hand_4 PF12763.2 EEB07426.2 - 2.2e-36 123.7 0.0 1.8e-13 50.1 0.0 3.8 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EEB07426.2 - 1.1e-08 35.1 0.0 9.4e-05 22.4 0.0 3.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EEB07426.2 - 1.3e-05 24.0 0.0 0.88 9.0 0.0 4.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EEB07426.2 - 0.0002 20.9 0.3 0.78 9.7 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.1 EEB07426.2 - 0.0091 15.5 0.0 0.79 9.3 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain pair Reo_sigmaC PF04582.7 EEB07426.2 - 0.92 8.6 12.4 0.34 10.0 6.1 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein THOC7 PF05615.8 EEB07426.2 - 1.2 9.4 30.1 4.1 7.6 10.8 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 EEB07426.2 - 3.1 7.5 43.7 1.6 8.4 11.9 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 EEB07426.2 - 4.1 6.7 33.6 1.4 8.2 7.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) ubiquitin PF00240.18 EEB07427.1 - 1.6e-07 30.6 0.1 2.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEB07427.1 - 0.0019 17.8 0.1 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EEB07427.1 - 0.003 17.4 0.2 0.019 14.8 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EEB07427.1 - 0.051 13.8 0.2 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 CENP-T PF15511.1 EEB07428.1 - 6.3e-47 160.7 23.2 1.5e-46 159.4 16.1 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EEB07428.1 - 1.2e-09 38.2 0.4 2.7e-09 37.0 0.3 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EEB07428.1 - 3.7e-06 26.9 2.5 5.3e-06 26.4 0.2 2.3 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB07428.1 - 0.00024 21.0 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EEB07428.1 - 0.0015 18.3 0.1 0.0045 16.7 0.1 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EEB07428.1 - 0.0032 17.1 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Striatin PF08232.7 EEB07429.2 - 7.5e-24 84.5 6.9 1.3e-23 83.8 4.8 1.3 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 EEB07429.2 - 1.1e-10 41.0 3.5 0.00015 21.5 0.1 6.2 6 1 0 6 6 6 2 WD domain, G-beta repeat RasGAP_C PF03836.10 EEB07429.2 - 0.013 15.1 0.6 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 RasGAP C-terminus PQQ_2 PF13360.1 EEB07429.2 - 0.041 13.3 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain AhpC-TSA PF00578.16 EEB07430.1 - 2e-25 88.8 0.0 2.4e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEB07430.1 - 4.5e-18 65.1 0.0 4.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EEB07430.1 - 0.0002 21.2 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CDC50 PF03381.10 EEB07431.1 - 5.2e-98 327.6 0.0 6.2e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family tRNA-synt_2 PF00152.15 EEB07432.1 - 2.2e-69 233.8 0.0 4.4e-69 232.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEB07432.1 - 3.8e-11 42.6 0.0 6.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.26 EEB07433.1 - 2e-20 72.2 1.9 4.3e-20 71.2 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_15 PF01793.11 EEB07434.1 - 3.7e-123 410.7 13.6 4.7e-123 410.3 9.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Exonuc_X-T_C PF08411.5 EEB07434.1 - 0.015 14.3 0.3 0.024 13.6 0.2 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal Ran_BP1 PF00638.13 EEB07435.1 - 2.1e-48 163.3 0.7 2.1e-48 163.3 0.5 1.6 2 0 0 2 2 2 1 RanBP1 domain SNF2_N PF00176.18 EEB07436.1 - 5e-73 245.5 0.0 8.9e-73 244.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB07436.1 - 2.8e-14 52.7 0.1 7.5e-14 51.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EEB07436.1 - 1.1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain UBA_4 PF14555.1 EEB07436.1 - 1.4e-08 34.1 0.2 3e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ResIII PF04851.10 EEB07436.1 - 3.1e-07 30.3 0.0 1.1e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EEB07436.1 - 4.3e-05 23.0 15.3 8.7e-05 22.1 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB07436.1 - 0.00014 21.8 13.7 0.00029 20.7 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB07436.1 - 0.0007 19.3 12.8 0.0015 18.3 8.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEB07436.1 - 0.0019 17.8 12.6 0.0043 16.7 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD_2 PF06733.10 EEB07436.1 - 0.014 14.8 1.6 0.021 14.2 0.0 2.2 2 1 1 3 3 3 0 DEAD_2 zf-C3HC4_4 PF15227.1 EEB07436.1 - 1.2 9.0 12.8 2.5 8.0 8.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_S3Ae PF01015.13 EEB07437.1 - 7.7e-80 266.8 5.3 9.2e-80 266.5 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF3888 PF13027.1 EEB07437.1 - 0.19 11.6 1.1 1.1 9.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3888) DUF4168 PF13767.1 EEB07437.1 - 0.26 11.9 2.6 0.36 11.4 1.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Phosphodiest PF01663.17 EEB07438.1 - 4.7e-19 68.9 1.1 9.8e-13 48.1 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEB07438.1 - 0.0004 19.6 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 EEB07438.1 - 0.17 11.2 0.2 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily zf-Tim10_DDP PF02953.10 EEB07439.1 - 2e-19 68.6 3.5 2e-19 68.6 2.4 1.7 2 0 0 2 2 2 1 Tim10/DDP family zinc finger HCNGP PF07818.8 EEB07439.1 - 0.036 14.1 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 HCNGP-like protein DUF2281 PF10047.4 EEB07439.1 - 0.069 13.4 0.1 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) TRAPP PF04051.11 EEB07440.1 - 2.1e-25 89.0 0.0 3.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pet127 PF08634.5 EEB07441.1 - 1e-87 293.7 0.5 1.4e-87 293.3 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 UBN2_2 PF14227.1 EEB07441.1 - 0.28 10.7 1.8 19 4.8 0.3 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DNA_ligase_A_M PF01068.16 EEB07442.1 - 1e-51 175.1 0.2 2.6e-51 173.9 0.1 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEB07442.1 - 7.8e-35 120.2 0.0 2.3e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEB07442.1 - 1.2e-13 51.2 0.0 4.9e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EEB07442.1 - 7.7e-08 32.3 0.6 0.00077 19.5 0.0 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EEB07442.1 - 0.0001 22.0 1.2 0.0058 16.3 0.8 3.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 EEB07442.1 - 0.032 14.0 0.1 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain UDG PF03167.14 EEB07443.2 - 3.1e-23 81.9 0.1 4.8e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec2p PF06428.6 EEB07444.1 - 1.6e-08 34.3 8.3 2.2e-08 33.8 5.7 1.2 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Histone PF00125.19 EEB07444.1 - 0.025 14.6 1.2 0.054 13.6 0.4 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HlyD PF00529.15 EEB07444.1 - 0.029 13.6 2.9 0.033 13.4 2.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HR1 PF02185.11 EEB07444.1 - 0.98 9.2 9.5 2.3 8.0 6.4 1.8 1 1 1 2 2 2 0 Hr1 repeat DivIVA PF05103.8 EEB07444.1 - 1.3 9.1 8.5 4.4 7.3 5.7 1.8 1 1 0 1 1 1 0 DivIVA protein S1 PF00575.18 EEB07445.1 - 6.4e-91 298.5 22.8 6e-14 51.8 0.3 13.0 12 1 0 12 12 12 11 S1 RNA binding domain TPR_19 PF14559.1 EEB07445.1 - 1.2e-09 38.3 0.2 0.00014 22.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB07445.1 - 2.5e-09 37.5 0.0 0.0053 17.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EEB07445.1 - 3.3e-09 36.8 0.1 3.8e-07 30.1 0.0 4.1 3 2 1 4 4 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EEB07445.1 - 1.2e-05 25.5 1.2 0.39 11.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEB07445.1 - 0.00083 19.6 2.1 0.33 11.5 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEB07445.1 - 0.0046 16.8 1.2 0.076 12.9 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat PilZ PF07238.9 EEB07445.1 - 0.0073 16.2 1.5 2.8 7.9 0.0 4.7 4 0 0 4 4 4 1 PilZ domain TPR_11 PF13414.1 EEB07445.1 - 0.0081 15.7 0.2 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EEB07445.1 - 0.15 12.0 0.1 23 5.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3366 PF11846.3 EEB07445.1 - 0.42 10.4 0.0 2.3 8.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) DUF2187 PF09953.4 EEB07445.1 - 0.54 10.0 3.7 20 5.0 0.4 4.3 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2187) EXOSC1 PF10447.4 EEB07445.1 - 0.57 10.1 4.2 3 7.8 0.4 4.2 5 0 0 5 5 4 0 Exosome component EXOSC1/CSL4 Ribosomal_L1 PF00687.16 EEB07446.1 - 1.2e-51 175.2 1.8 1.4e-51 174.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MS_channel PF00924.13 EEB07447.1 - 5.7e-22 78.0 2.4 1.2e-21 77.0 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEB07447.1 - 0.0063 15.7 0.1 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEB07447.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain CCDC-167 PF15188.1 EEB07447.1 - 0.26 11.2 2.7 0.42 10.5 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Bac_rhodopsin PF01036.13 EEB07448.2 - 2.6e-11 43.2 1.8 3.1e-11 43.0 1.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4184 PF13803.1 EEB07448.2 - 0.18 11.0 1.4 0.32 10.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) SAP PF02037.22 EEB07449.1 - 5.5e-14 51.2 0.4 1.1e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 SAP domain Ribosomal_L11_N PF03946.9 EEB07450.1 - 6.3e-17 60.7 0.1 9.6e-17 60.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEB07450.1 - 8e-12 45.1 0.4 1.8e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EEB07450.1 - 0.044 13.4 0.0 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region Metallophos PF00149.23 EEB07451.1 - 2.6e-43 147.7 0.4 3.2e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EEB07453.2 - 6.5e-08 32.1 0.0 0.00015 21.5 0.0 4.1 4 1 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEB07453.2 - 0.00075 19.2 0.0 0.028 14.1 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Sec23_trunk PF04811.10 EEB07454.1 - 1e-77 260.8 0.0 1.5e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEB07454.1 - 1.1e-33 114.6 0.1 2.3e-33 113.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEB07454.1 - 1.9e-31 108.4 0.7 3.9e-31 107.4 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEB07454.1 - 1.4e-15 56.5 6.6 2.5e-15 55.7 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEB07454.1 - 5.5e-14 51.6 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Exo_endo_phos PF03372.18 EEB07455.2 - 1.3e-23 84.2 0.1 1.8e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EEB07455.2 - 5.9e-09 35.3 0.2 1.5e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB07455.2 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EEB07455.2 - 0.0058 16.4 0.2 0.064 13.3 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_7 PF13504.1 EEB07455.2 - 0.057 13.6 0.8 1.1 9.7 0.2 3.2 3 0 0 3 3 3 0 Leucine rich repeat WD40 PF00400.27 EEB07456.1 - 2e-60 198.6 19.7 1.5e-11 43.7 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEB07456.1 - 4.2e-47 159.7 1.6 7.9e-47 158.9 1.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EEB07456.1 - 4.6e-05 23.0 0.0 9.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EEB07456.1 - 0.0018 16.4 2.9 0.23 9.5 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.6 EEB07456.1 - 0.062 12.5 0.0 7.9 5.6 0.0 2.9 2 1 0 3 3 3 0 TUP1-like enhancer of split Peptidase_C50 PF03568.12 EEB07457.1 - 2.8e-123 411.3 0.0 7.5e-123 409.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EEB07457.1 - 0.022 13.9 0.1 2.2 7.3 0.0 3.1 2 1 0 2 2 2 0 CHAT domain TPR_12 PF13424.1 EEB07457.1 - 0.34 10.8 3.7 3.3 7.7 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EEB07458.1 - 4.2e-20 72.6 0.0 5.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB07458.1 - 1.7e-18 66.7 0.0 2.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEB07458.1 - 1.4e-15 56.8 0.0 3.6e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EEB07458.1 - 2.4e-10 40.3 0.0 3.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEB07458.1 - 9.9e-05 21.8 0.0 0.57 9.5 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEB07458.1 - 0.0016 17.7 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EEB07458.1 - 0.06 12.7 0.0 0.073 12.4 0.0 1.3 1 1 0 1 1 1 0 Putative esterase SMC_N PF02463.14 EEB07460.1 - 7.3e-27 94.0 0.0 1.9e-26 92.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEB07460.1 - 8.2e-09 36.0 75.1 5.5e-08 33.3 25.7 5.7 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EEB07460.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EEB07460.1 - 0.0057 16.6 0.7 0.0057 16.6 0.5 4.1 4 1 0 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 EEB07460.1 - 6.8 5.7 16.6 6.2 5.9 2.6 3.4 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Ribosomal_L18e PF00828.14 EEB07461.1 - 3.2e-32 111.6 0.1 3.9e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Rpr2 PF04032.11 EEB07462.1 - 1.3e-13 50.5 2.2 2.1e-13 49.9 1.5 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.9 EEB07462.1 - 0.0043 16.9 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27e PF01667.12 EEB07462.1 - 0.12 11.9 1.5 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 DUF1178 PF06676.6 EEB07462.1 - 0.87 9.7 3.5 10 6.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) DUF155 PF02582.9 EEB07463.1 - 2.6e-52 177.2 1.2 3.9e-52 176.6 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Atg14 PF10186.4 EEB07464.1 - 0.008 15.1 3.3 0.0082 15.1 2.3 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EEB07464.1 - 0.027 14.8 0.7 0.03 14.7 0.5 1.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HAUS6_N PF14661.1 EEB07464.1 - 0.098 11.9 1.5 0.11 11.8 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FlaC_arch PF05377.6 EEB07464.1 - 0.1 12.5 0.6 0.4 10.6 0.1 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.1 EEB07464.1 - 0.12 12.7 2.7 0.93 9.8 0.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin SlyX PF04102.7 EEB07464.1 - 0.12 12.7 0.9 0.17 12.3 0.6 1.2 1 0 0 1 1 1 0 SlyX DUF2681 PF10883.3 EEB07464.1 - 0.13 12.4 2.1 0.15 12.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Neurochondrin PF05536.6 EEB07465.1 - 3.8e-63 213.6 4.7 9.2e-63 212.3 3.2 1.5 1 1 0 1 1 1 1 Neurochondrin Rotamase PF00639.16 EEB07466.1 - 1.7e-26 92.7 0.0 2.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EEB07466.1 - 4.3e-22 78.5 0.0 5.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EEB07466.1 - 2.1e-07 30.6 0.5 2.1e-07 30.6 0.3 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EEB07466.1 - 4e-07 30.6 0.0 5.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNase_P_pop3 PF08228.6 EEB07467.1 - 1.2e-19 70.7 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 RRM_1 PF00076.17 EEB07468.1 - 1.5e-18 66.1 0.0 2.9e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07468.1 - 5.4e-09 35.9 0.0 2.9e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07468.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EEB07469.1 - 4e-140 467.4 19.5 5.2e-140 467.0 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Yippee-Mis18 PF03226.9 EEB07470.2 - 2.9e-22 78.4 0.7 2.9e-22 78.4 0.5 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 EEB07470.2 - 0.02 14.5 0.2 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HECT_2 PF09814.4 EEB07470.2 - 0.03 13.0 0.7 2.5 6.7 0.0 2.2 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.3 EEB07470.2 - 0.047 13.5 0.2 0.094 12.5 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain of RIG-I E7 PF00527.13 EEB07470.2 - 0.16 12.1 1.7 2.2 8.4 0.0 2.5 1 1 0 2 2 2 0 E7 protein, Early protein ERCC4 PF02732.10 EEB07471.2 - 9e-26 90.3 0.0 3.1e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain HMG_box PF00505.14 EEB07472.1 - 1.3e-12 47.7 10.9 5.5e-12 45.7 1.3 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EEB07472.1 - 7.9e-12 45.3 6.8 4.5e-11 42.9 0.7 3.3 2 2 0 2 2 2 1 HMG-box domain Casc1 PF12366.3 EEB07472.1 - 0.0027 17.2 1.4 0.0027 17.2 0.9 2.5 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 MAS20 PF02064.10 EEB07472.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.8 2 1 1 3 3 3 0 MAS20 protein import receptor KfrA_N PF11740.3 EEB07472.1 - 5.5 7.4 9.3 0.81 10.1 0.1 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term V_ATPase_I PF01496.14 EEB07472.1 - 8.5 4.0 10.4 11 3.7 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DEAD PF00270.24 EEB07473.1 - 5.4e-45 152.9 0.0 2.7e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07473.1 - 2e-23 82.0 0.0 6.8e-23 80.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEB07473.1 - 0.0019 17.0 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Oxidored-like PF09791.4 EEB07474.1 - 2.3e-19 68.5 2.4 3.4e-19 67.9 1.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DnaJ PF00226.26 EEB07475.1 - 4.3e-21 74.4 0.9 4.3e-21 74.4 0.6 2.3 3 0 0 3 3 3 1 DnaJ domain RRM_1 PF00076.17 EEB07475.1 - 0.0011 18.5 0.0 0.0035 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07475.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07475.1 - 0.081 12.9 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SpoIISB_antitox PF14185.1 EEB07475.1 - 0.13 12.0 7.4 0.12 12.0 3.1 2.4 1 1 1 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system Iron_permease PF04120.7 EEB07475.1 - 5.6 6.5 5.8 13 5.3 4.0 1.6 1 0 0 1 1 1 0 Low affinity iron permease WD40 PF00400.27 EEB07476.1 - 6.3e-14 51.2 11.7 0.00019 21.1 0.4 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Proteasome PF00227.21 EEB07477.2 - 3.6e-46 156.8 0.1 4.6e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB07477.2 - 3.3e-14 51.8 0.1 5.4e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rad17 PF03215.10 EEB07478.1 - 6.3e-90 302.3 0.0 6.8e-62 209.8 0.0 2.0 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEB07478.1 - 6.1e-06 26.4 0.0 2.3e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB07478.1 - 3.2e-05 23.9 0.0 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EEB07478.1 - 6.4e-05 23.0 0.0 0.0013 18.8 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EEB07478.1 - 0.00014 21.9 0.0 0.00062 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB07478.1 - 0.00093 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EEB07478.1 - 0.0014 19.4 0.0 0.0062 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEB07478.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EEB07478.1 - 0.0044 15.9 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 EEB07478.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEB07478.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEB07478.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEB07478.1 - 0.032 14.5 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEB07478.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EEB07478.1 - 0.035 13.5 0.5 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EEB07478.1 - 0.037 13.9 0.0 0.094 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEB07478.1 - 0.04 13.4 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EEB07478.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEB07478.1 - 0.093 11.5 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EEB07479.2 - 5.8e-70 235.1 0.0 8.3e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEB07479.2 - 1.7e-24 86.4 0.0 4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEB07479.2 - 2.5e-17 62.8 2.1 6.1e-17 61.5 0.7 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEB07479.2 - 0.007 16.2 0.7 0.034 14.0 0.4 2.1 1 1 1 2 2 2 1 HAS barrel domain DPPIV_N PF00930.16 EEB07480.1 - 1.9e-52 177.9 0.3 2.7e-52 177.5 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEB07480.1 - 8.4e-24 83.9 0.1 1.5e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EEB07480.1 - 3.1e-06 26.7 0.1 1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EEB07480.1 - 2e-05 24.3 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB07480.1 - 5.2e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEB07480.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EEB07480.1 - 0.92 8.8 6.0 0.31 10.4 0.0 2.8 3 1 1 4 4 4 0 X-Pro dipeptidyl-peptidase (S15 family) SH3_9 PF14604.1 EEB07481.1 - 2e-29 100.9 2.1 1.3e-14 53.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEB07481.1 - 1.8e-27 94.4 1.6 2.4e-13 49.2 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EEB07481.1 - 2.5e-20 71.6 0.1 8.1e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EEB07481.1 - 3e-14 52.9 0.0 5.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NIF PF03031.13 EEB07482.2 - 4.8e-19 68.5 0.3 6.6e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Zn_clus PF00172.13 EEB07484.2 - 2.6e-07 30.4 9.8 4e-07 29.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sorting_nexin PF03700.8 EEB07484.2 - 0.77 9.8 7.4 0.4 10.7 2.0 2.6 3 0 0 3 3 3 0 Sorting nexin, N-terminal domain GRASP55_65 PF04495.9 EEB07485.1 - 0.0067 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EEB07485.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 EEB07485.1 - 0.041 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Siah-Interact_N PF09032.6 EEB07485.1 - 6.1 6.9 8.8 3.6 7.6 0.9 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal SNF2_N PF00176.18 EEB07486.1 - 5.8e-71 238.7 0.5 1.1e-70 237.7 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB07486.1 - 1.5e-15 56.7 0.0 3.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB07486.1 - 3e-11 43.5 0.0 9.5e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.8 EEB07486.1 - 7.7e-07 28.8 0.6 7.7e-07 28.8 0.4 3.3 2 1 2 4 4 4 1 HSA DEAD PF00270.24 EEB07486.1 - 2.6e-05 23.7 0.0 6.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Membr_traf_MHD PF10540.4 EEB07487.2 - 1.5e-23 83.1 0.6 7.2e-23 80.8 0.0 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EEB07487.2 - 9.4e-06 25.3 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EEB07488.1 - 1.8e-38 130.0 0.0 7.8e-15 54.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07488.1 - 1.5e-21 76.1 0.0 1.8e-09 37.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07488.1 - 2.1e-20 72.3 0.0 5.1e-09 35.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB07488.1 - 2.6e-07 30.3 0.0 0.0011 18.6 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif SNF2_N PF00176.18 EEB07489.1 - 2.9e-71 239.7 0.2 5.7e-71 238.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB07489.1 - 4.9e-16 58.3 0.1 2.2e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB07489.1 - 3e-06 27.1 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tudor-knot PF11717.3 EEB07489.1 - 0.1 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain 14-3-3 PF00244.15 EEB07490.1 - 3.8e-116 386.2 7.2 4.3e-116 386.0 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EEB07490.1 - 2.7e-05 23.7 3.4 0.11 12.0 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF837) Vma12 PF11712.3 EEB07490.1 - 0.014 15.0 0.7 0.03 14.0 0.5 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CofC PF01983.11 EEB07490.1 - 0.031 13.2 0.8 0.047 12.6 0.6 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like SPACA7 PF15307.1 EEB07490.1 - 0.05 13.7 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 HisKA PF00512.20 EEB07490.1 - 0.078 12.9 0.2 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF885 PF05960.6 EEB07490.1 - 0.44 9.6 6.6 0.13 11.3 2.3 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) CCDC-167 PF15188.1 EEB07490.1 - 1.6 8.6 6.0 0.94 9.4 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 PPR_2 PF13041.1 EEB07491.1 - 0.017 15.0 0.0 0.49 10.4 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family PPR_3 PF13812.1 EEB07491.1 - 0.051 13.8 0.1 0.33 11.3 0.0 2.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain CorA PF01544.13 EEB07492.1 - 5.7e-51 173.2 0.0 8.5e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.23 EEB07493.1 - 1.2e-13 50.8 9.8 2.5e-13 49.9 6.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RTA1 PF04479.8 EEB07494.1 - 5.4e-56 189.5 6.2 7.5e-56 189.1 4.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Metallophos PF00149.23 EEB07495.1 - 2.2e-13 50.0 6.0 3.8e-13 49.2 4.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EEB07495.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Prenyltrans PF00432.16 EEB07496.1 - 8.1e-37 124.4 18.2 8.2e-10 38.0 0.5 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEB07496.1 - 2.9e-30 104.9 0.8 3.3e-14 53.2 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEB07496.1 - 4.2e-08 33.1 0.0 0.00022 21.2 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like BRO1 PF03097.13 EEB07497.1 - 3.3e-85 286.1 0.7 3.3e-85 286.1 0.5 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEB07497.1 - 1.2e-48 165.6 12.6 2.4e-48 164.6 8.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3383 PF11863.3 EEB07497.1 - 0.014 14.1 0.5 0.025 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Ribosomal_S24e PF01282.14 EEB07498.1 - 8.9e-33 111.9 0.1 1.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EEB07498.1 - 0.064 12.4 1.2 0.07 12.3 0.9 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 RRXRR PF14239.1 EEB07498.1 - 0.089 12.1 4.4 0.1 12.0 3.1 1.2 1 0 0 1 1 1 0 RRXRR protein Use1 PF09753.4 EEB07499.1 - 2.1e-10 40.4 6.7 2.3e-10 40.3 4.7 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF912 PF06024.7 EEB07499.1 - 0.99 9.4 3.2 1.2 9.2 0.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Exonuc_VII_L PF02601.10 EEB07499.1 - 5.8 6.0 10.7 7.5 5.6 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FYVE PF01363.16 EEB07500.1 - 2.1e-22 78.7 27.0 9.6e-13 47.8 6.9 3.2 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EEB07500.1 - 3.5e-05 23.5 5.7 3.5e-05 23.5 4.0 3.9 4 0 0 4 4 4 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EEB07500.1 - 0.0073 16.5 1.8 0.0073 16.5 1.2 2.7 2 0 0 2 2 2 1 Tc5 transposase C-terminal domain IBR PF01485.16 EEB07500.1 - 0.0093 15.8 1.2 0.0093 15.8 0.8 3.5 5 0 0 5 5 5 2 IBR domain Trm112p PF03966.11 EEB07500.1 - 0.78 10.1 9.7 24 5.3 0.0 3.1 2 2 0 2 2 2 0 Trm112p-like protein HypA PF01155.14 EEB07500.1 - 2.6 7.7 15.6 3.3 7.4 4.2 3.8 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Sec62 PF03839.11 EEB07501.1 - 1.9e-58 197.5 2.7 2.8e-58 196.9 1.8 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.16 EEB07501.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PepSY_TM_2 PF13703.1 EEB07501.1 - 2.3 8.4 6.8 18 5.5 4.7 2.3 1 1 0 1 1 1 0 PepSY-associated TM helix SWIRM PF04433.12 EEB07502.1 - 2.4e-32 110.8 0.0 6.4e-32 109.5 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EEB07502.1 - 5.9e-08 32.6 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB07502.1 - 1.1e-05 25.4 0.1 4.1e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EEB07502.1 - 0.17 11.4 1.1 0.36 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type SKN1 PF03935.10 EEB07503.1 - 1.7e-220 732.4 2.9 2.1e-220 732.1 2.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cullin PF00888.17 EEB07504.2 - 2.3e-180 601.0 12.9 3.3e-180 600.5 9.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEB07504.2 - 1.3e-26 92.2 7.1 6.5e-26 89.9 3.7 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.20 EEB07505.1 - 3.4e-74 249.2 0.0 4.1e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07505.1 - 6.5e-32 110.6 0.0 8.8e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEB07505.1 - 5.9e-05 22.2 0.1 0.00024 20.2 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEB07505.1 - 0.00017 20.6 0.0 0.058 12.3 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EEB07505.1 - 0.0004 20.1 0.1 0.0016 18.2 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEB07505.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HAD_2 PF13419.1 EEB07506.2 - 5e-31 108.2 0.1 6.3e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB07506.2 - 4e-06 26.4 0.2 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EEB07506.2 - 6e-06 26.8 0.0 4e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EEB07506.2 - 0.016 14.8 0.0 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Acid_PPase PF12689.2 EEB07506.2 - 0.017 14.7 0.0 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase Arb1 PF09692.5 EEB07507.2 - 8.9e-77 258.5 0.0 2.1e-67 227.6 0.0 2.0 2 0 0 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RHD3 PF05879.7 EEB07508.1 - 5.4e-228 758.6 14.2 8e-228 758.0 9.8 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EEB07508.1 - 2.5e-08 33.2 0.6 2.5e-08 33.2 0.4 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EEB07508.1 - 2.9e-06 27.2 0.2 8.8e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EEB07508.1 - 4.3e-06 26.6 0.1 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEB07508.1 - 3.2e-05 24.3 0.1 0.00012 22.5 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EEB07508.1 - 0.0012 18.8 3.1 0.031 14.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EEB07508.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EEB07508.1 - 0.092 11.9 0.1 0.25 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 EEB07508.1 - 0.12 11.7 2.0 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.13 EEB07508.1 - 0.19 10.9 1.5 0.48 9.6 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B COMPASS-Shg1 PF05205.7 EEB07508.1 - 0.67 10.2 4.7 5.4 7.3 0.2 3.4 2 1 1 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 6PF2K PF01591.13 EEB07509.1 - 2.8e-72 242.3 0.5 4.6e-72 241.6 0.4 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEB07509.1 - 3.3e-14 53.2 0.2 9.1e-14 51.8 0.0 1.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEB07509.1 - 1.8e-06 27.8 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB07509.1 - 0.00014 22.6 0.4 0.0004 21.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EEB07509.1 - 0.039 13.1 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ribosomal_L18e PF00828.14 EEB07510.1 - 3.4e-27 95.3 0.4 3.4e-27 95.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Pput2613-deam PF14427.1 EEB07510.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase ATP-synt_ab PF00006.20 EEB07511.1 - 2.2e-63 213.6 0.0 3.2e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEB07511.1 - 4.8e-28 97.8 0.3 9.9e-28 96.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEB07511.1 - 2e-22 79.1 0.3 4e-22 78.2 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EEB07511.1 - 0.00051 19.2 0.1 0.0012 18.0 0.1 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EEB07511.1 - 0.0013 18.1 0.3 0.025 13.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEB07511.1 - 0.0058 16.3 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EEB07511.1 - 0.0086 15.7 0.2 0.49 10.1 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EEB07511.1 - 0.018 15.0 0.1 0.14 12.1 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EEB07511.1 - 0.018 14.6 0.1 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EEB07511.1 - 0.038 14.1 0.0 0.76 9.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEB07511.1 - 0.05 13.7 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EEB07511.1 - 0.057 12.6 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEB07511.1 - 0.12 12.4 0.1 0.53 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEB07511.1 - 0.34 9.7 0.9 0.59 8.9 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain Pyr_redox_2 PF07992.9 EEB07512.2 - 1.1e-07 31.9 0.3 6.6e-06 26.1 0.2 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEB07512.2 - 0.031 14.0 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Malic_M PF03949.10 EEB07512.2 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Cupin_2 PF07883.6 EEB07512.2 - 0.1 12.0 0.1 5.5 6.5 0.0 2.7 2 1 0 2 2 2 0 Cupin domain RNA_pol_Rbc25 PF08292.7 EEB07513.1 - 1.7e-39 134.7 0.0 2.6e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EEB07513.1 - 4e-17 62.0 0.0 7.2e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEB07513.1 - 0.0015 18.5 0.0 0.004 17.2 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain GTP_EFTU PF00009.22 EEB07514.2 - 1.1e-42 145.6 0.2 4.1e-42 143.7 0.0 1.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EEB07514.2 - 1.5e-16 60.2 4.8 2.9e-16 59.3 3.3 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 EEB07514.2 - 8.4e-08 32.2 0.2 1.1e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB07514.2 - 2.9e-06 27.2 0.0 0.01 15.7 0.0 3.5 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EEB07514.2 - 0.00039 20.5 0.1 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain DUF87 PF01935.12 EEB07514.2 - 2.8 7.6 7.4 2.4 7.9 2.6 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 EEB07515.1 - 3.3e-61 205.5 0.0 8.1e-30 103.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEB07515.1 - 2.1e-52 178.2 45.1 9.9e-29 100.5 13.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEB07515.1 - 2.1e-16 60.7 4.8 2.9e-05 24.1 0.1 4.4 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EEB07515.1 - 4.4e-15 55.5 5.1 5e-05 22.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EEB07515.1 - 2.2e-10 39.7 0.2 0.00096 17.8 0.0 3.9 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEB07515.1 - 4.7e-10 40.3 0.3 0.00025 21.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEB07515.1 - 1.5e-09 38.2 0.0 0.0015 18.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EEB07515.1 - 1.2e-08 34.2 0.8 0.0045 16.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEB07515.1 - 7.9e-07 29.2 0.2 0.0027 17.7 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_10 PF12846.2 EEB07515.1 - 9.8e-07 28.4 2.3 0.53 9.6 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 EEB07515.1 - 2.3e-06 27.7 2.6 0.19 11.8 0.2 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEB07515.1 - 1.4e-05 24.5 0.4 0.024 14.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEB07515.1 - 3.9e-05 23.2 0.2 0.023 14.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 EEB07515.1 - 9.7e-05 21.6 0.0 0.35 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEB07515.1 - 0.00013 22.3 0.1 0.13 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EEB07515.1 - 0.00016 21.1 0.6 0.18 11.1 0.0 2.6 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EEB07515.1 - 0.00017 21.4 0.1 0.74 9.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEB07515.1 - 0.00022 21.0 0.3 0.23 11.4 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 EEB07515.1 - 0.0011 18.1 0.0 0.36 9.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEB07515.1 - 0.0027 17.8 0.1 12 6.1 0.0 3.7 3 0 0 3 3 3 0 RNA helicase APS_kinase PF01583.15 EEB07515.1 - 0.0036 16.9 1.5 1.1 8.8 0.0 2.9 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_19 PF13245.1 EEB07515.1 - 0.005 16.5 0.0 0.39 10.5 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EEB07515.1 - 0.0054 16.3 2.6 2 8.0 0.0 3.6 3 0 0 3 3 3 1 NACHT domain DUF3987 PF13148.1 EEB07515.1 - 0.0075 14.8 0.1 0.42 9.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) PRK PF00485.13 EEB07515.1 - 0.012 15.2 0.0 4.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 EEB07515.1 - 0.013 15.2 0.0 7.3 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEB07515.1 - 0.014 15.3 0.0 1.3 8.8 0.0 3.5 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EEB07515.1 - 0.021 13.9 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EEB07515.1 - 0.054 12.9 4.1 9.1 5.6 0.0 4.2 5 0 0 5 5 4 0 IstB-like ATP binding protein MobB PF03205.9 EEB07515.1 - 0.067 12.9 0.9 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 EEB07515.1 - 0.081 12.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.1 EEB07515.1 - 0.21 11.1 0.2 14 5.1 0.0 3.1 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.4 EEB07515.1 - 0.23 10.4 0.0 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EEB07515.1 - 0.92 9.2 8.0 4.8 6.9 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 MMR_HSR1_C PF08438.5 EEB07517.1 - 5e-30 103.9 0.0 8.8e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EEB07517.1 - 2.1e-18 66.3 0.0 5.2e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB07517.1 - 4e-07 29.4 0.1 5.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB07517.1 - 0.0013 18.5 0.5 0.0068 16.2 0.0 2.3 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EEB07517.1 - 0.0018 17.7 0.2 0.93 8.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EEB07517.1 - 0.0051 16.3 0.2 2 7.9 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein ArgK PF03308.11 EEB07517.1 - 0.0079 14.9 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 EEB07517.1 - 0.045 14.0 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEB07517.1 - 0.12 12.7 0.8 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 EEB07517.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EEB07517.1 - 0.14 11.6 0.9 6.4 6.1 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EEB07517.1 - 0.14 11.6 0.9 0.28 10.7 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.17 EEB07518.1 - 2.2e-48 163.7 0.6 2.5e-48 163.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB07518.1 - 4.5e-17 62.6 0.2 6e-17 62.2 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB07518.1 - 1.3e-07 31.0 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB07518.1 - 7e-07 28.8 0.2 1.1e-05 24.9 0.1 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEB07518.1 - 2.9e-06 27.2 0.1 5.6e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEB07518.1 - 2.2e-05 23.7 0.1 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EEB07518.1 - 0.0025 17.5 0.6 0.0048 16.6 0.4 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EEB07518.1 - 0.005 16.7 0.1 0.0068 16.3 0.1 1.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EEB07518.1 - 0.015 14.6 0.1 0.12 11.6 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.1 EEB07518.1 - 0.042 13.7 0.1 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain WAPL PF07814.8 EEB07519.1 - 1.4e-19 70.1 9.0 3.2e-18 65.6 3.7 2.4 1 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin NifW PF03206.9 EEB07519.1 - 0.095 12.8 0.5 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 Nitrogen fixation protein NifW tRNA_NucTran2_2 PF13735.1 EEB07519.1 - 0.1 12.3 0.8 2.4 7.9 0.0 2.6 3 0 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative CDT1 PF08839.6 EEB07520.1 - 8.7e-07 29.0 1.8 3e-06 27.2 0.1 2.5 2 1 0 2 2 2 1 DNA replication factor CDT1 like DNA_pol3_tau_4 PF12168.3 EEB07520.1 - 6.3 7.2 13.8 3.2 8.2 2.8 3.2 3 1 0 3 3 3 0 DNA polymerase III subunits tau domain IV DnaB-binding UTP15_C PF09384.5 EEB07521.1 - 2e-46 157.3 0.1 6.6e-46 155.6 0.0 1.8 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EEB07521.1 - 5.3e-28 95.8 12.0 2.7e-10 39.7 0.4 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Spc97_Spc98 PF04130.8 EEB07522.2 - 1.6e-109 366.6 9.4 2.6e-109 365.9 6.5 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family AAA PF00004.24 EEB07523.1 - 1.4e-11 44.7 0.0 3.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB07523.1 - 1.6e-07 31.5 0.0 5.1e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEB07523.1 - 1.6e-07 31.2 0.0 6.7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EEB07523.1 - 1.9e-07 30.1 0.1 3.6e-05 22.6 0.0 3.0 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EEB07523.1 - 2.7e-07 30.2 0.1 7.2e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEB07523.1 - 8.2e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEB07523.1 - 8.7e-07 29.7 0.0 3.4e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB07523.1 - 4e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB07523.1 - 4.3e-05 23.8 0.0 0.00014 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEB07523.1 - 4.9e-05 22.5 0.0 0.00023 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EEB07523.1 - 5e-05 22.9 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EEB07523.1 - 6.7e-05 22.9 1.0 0.00032 20.7 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EEB07523.1 - 9e-05 21.6 0.0 0.00021 20.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EEB07523.1 - 0.00091 18.6 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEB07523.1 - 0.0018 18.2 0.1 0.0048 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain SKI PF01202.17 EEB07523.1 - 0.0033 17.3 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase NACHT PF05729.7 EEB07523.1 - 0.0034 17.0 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 EEB07523.1 - 0.0042 16.7 0.1 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 NTPase ABC_tran PF00005.22 EEB07523.1 - 0.0076 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 EEB07523.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 EEB07523.1 - 0.0097 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 KaiC Sigma54_activ_2 PF14532.1 EEB07523.1 - 0.01 15.8 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 EEB07523.1 - 0.012 14.8 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEB07523.1 - 0.014 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 EEB07523.1 - 0.017 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 EEB07523.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EEB07523.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EEB07523.1 - 0.031 13.1 0.0 0.065 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 EEB07523.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EEB07523.1 - 0.032 13.4 0.0 0.085 12.0 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EEB07523.1 - 0.046 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EEB07523.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EEB07523.1 - 0.06 12.2 0.1 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.6 EEB07523.1 - 0.072 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Polyoma_lg_T_C PF06431.6 EEB07523.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus UPF0079 PF02367.12 EEB07523.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Ribosomal_L3 PF00297.17 EEB07524.2 - 2.5e-193 640.0 14.5 4.1e-109 364.0 2.3 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 Big_3_3 PF13750.1 EEB07524.2 - 0.00076 18.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) ESAG1 PF03238.8 EEB07524.2 - 0.0021 17.4 2.7 1.6 7.9 0.1 2.8 3 0 0 3 3 3 2 ESAG protein Pyr_excise PF03013.9 EEB07524.2 - 0.0038 16.9 3.1 0.38 10.5 0.3 2.5 2 0 0 2 2 2 2 Pyrimidine dimer DNA glycosylase DUF1465 PF07323.7 EEB07524.2 - 0.015 14.8 0.0 7.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) FadA PF09403.5 EEB07524.2 - 0.068 13.1 6.0 0.49 10.4 0.8 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Med11 PF10280.4 EEB07524.2 - 0.21 11.6 0.9 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Mediator complex protein DUF829 PF05705.9 EEB07524.2 - 0.25 11.0 2.1 15 5.2 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) DUF3053 PF11254.3 EEB07524.2 - 0.5 9.5 5.6 6.2 5.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) DUF2456 PF10445.4 EEB07525.1 - 6.9e-29 99.6 4.5 3.9e-28 97.2 1.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF1769 PF08588.5 EEB07526.1 - 2.6e-20 72.0 0.3 5e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) tRNA-synt_2d PF01409.15 EEB07527.1 - 4.1e-46 157.1 0.1 1.4e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EEB07527.1 - 1.1e-20 73.5 0.0 4.5e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DUF2439 PF10382.4 EEB07528.2 - 3.5e-22 78.3 0.2 5.6e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) CN_hydrolase PF00795.17 EEB07530.1 - 4.3e-25 88.1 0.0 7.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EEB07530.1 - 1.3e-21 76.5 0.0 3.2e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EEB07530.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF1009 PF06230.6 EEB07530.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) AAA PF00004.24 EEB07531.1 - 9.7e-54 181.1 0.0 1.3e-39 135.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EEB07531.1 - 4.1e-19 68.4 0.5 1.2e-18 66.9 0.4 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EEB07531.1 - 4.9e-10 39.6 0.1 0.0039 17.1 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEB07531.1 - 1.6e-08 34.7 0.1 0.001 19.1 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEB07531.1 - 1.9e-07 31.0 0.0 0.0071 16.2 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EEB07531.1 - 3.8e-07 29.7 0.9 1.3 8.3 0.0 5.2 4 1 2 6 6 5 1 AAA domain IstB_IS21 PF01695.12 EEB07531.1 - 1.1e-06 28.1 0.0 0.012 15.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEB07531.1 - 1.8e-06 27.8 0.6 0.0028 17.3 0.0 3.6 2 2 1 3 3 3 1 Archaeal ATPase AAA_5 PF07728.9 EEB07531.1 - 9.9e-06 25.3 0.1 0.16 11.7 0.0 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.7 EEB07531.1 - 1.5e-05 24.7 0.2 0.016 14.8 0.1 3.1 2 1 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 EEB07531.1 - 1.7e-05 24.3 0.0 0.054 12.9 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EEB07531.1 - 2.3e-05 24.5 0.0 0.12 12.5 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 EEB07531.1 - 3.4e-05 23.5 0.0 0.09 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEB07531.1 - 3.7e-05 24.5 0.0 0.37 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EEB07531.1 - 0.00014 21.7 0.0 0.67 9.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 EEB07531.1 - 0.00019 20.3 0.0 0.22 10.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.1 EEB07531.1 - 0.00021 21.2 0.0 0.48 10.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEB07531.1 - 0.00027 20.1 0.0 0.22 10.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 EEB07531.1 - 0.00038 19.5 0.0 0.098 11.6 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EEB07531.1 - 0.0006 19.0 0.0 0.85 8.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_18 PF13238.1 EEB07531.1 - 0.00071 19.8 0.0 0.45 10.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EEB07531.1 - 0.00088 18.2 0.0 0.026 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EEB07531.1 - 0.00091 18.8 0.0 0.098 12.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EEB07531.1 - 0.0012 18.0 0.0 0.33 10.0 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EEB07531.1 - 0.0014 17.5 0.0 0.013 14.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EEB07531.1 - 0.0015 18.8 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 1 ABC transporter Kinesin PF00225.18 EEB07531.1 - 0.0019 16.9 0.0 1.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Kinesin motor domain MCM PF00493.18 EEB07531.1 - 0.0021 16.9 0.2 0.47 9.2 0.1 3.1 3 0 0 3 3 3 1 MCM2/3/5 family ResIII PF04851.10 EEB07531.1 - 0.0025 17.6 0.1 0.17 11.6 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 EEB07531.1 - 0.0032 16.4 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase FtsK_SpoIIIE PF01580.13 EEB07531.1 - 0.0032 16.9 0.0 0.036 13.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EEB07531.1 - 0.0037 16.9 0.0 0.015 14.9 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 EEB07531.1 - 0.0037 16.2 0.1 2.5 6.9 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EEB07531.1 - 0.0037 16.3 0.1 1.7 7.6 0.0 2.8 3 0 0 3 3 3 1 KaiC TIP49 PF06068.8 EEB07531.1 - 0.0042 15.8 0.0 0.19 10.4 0.0 2.6 3 0 0 3 3 3 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EEB07531.1 - 0.0048 16.9 0.0 3 7.8 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 EEB07531.1 - 0.0056 16.2 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 EEB07531.1 - 0.011 14.0 0.0 0.02 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_3 PF07726.6 EEB07531.1 - 0.017 14.7 0.0 2.8 7.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EEB07531.1 - 0.023 13.5 0.0 0.49 9.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EEB07531.1 - 0.079 12.7 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EEB07531.1 - 0.095 12.2 0.0 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EEB07531.1 - 0.11 12.0 0.0 4.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEB07531.1 - 0.12 12.3 0.0 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pro_isomerase PF00160.16 EEB07532.2 - 5.9e-48 162.9 0.0 1.1e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EEB07532.2 - 1.3e-08 34.3 3.2 0.0016 18.2 0.6 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Piwi PF02171.12 EEB07533.1 - 3.2e-95 318.5 0.0 4.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EEB07533.1 - 4.2e-21 74.6 0.0 7.7e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EEB07533.1 - 7.4e-18 63.6 0.3 1.5e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) YTH PF04146.10 EEB07534.2 - 1.1e-17 63.9 0.3 1.5e-17 63.5 0.2 1.2 1 0 0 1 1 1 1 YT521-B-like domain adh_short PF00106.20 EEB07535.1 - 6.7e-16 58.6 0.0 9.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB07535.1 - 7.9e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB07535.1 - 3.4e-06 26.8 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEB07535.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB07535.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEB07535.1 - 0.031 14.0 0.2 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HEAT PF02985.17 EEB07536.1 - 1.1e-12 46.8 7.2 0.14 12.3 0.3 8.1 8 1 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EEB07536.1 - 3.3e-09 36.9 0.0 1.5 9.1 0.0 4.8 4 0 0 4 4 4 4 HEAT repeats CLASP_N PF12348.3 EEB07536.1 - 1.4e-05 24.5 3.0 0.00027 20.3 0.2 3.6 3 2 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.1 EEB07536.1 - 0.021 15.2 5.5 5.3 7.6 0.0 5.0 4 1 1 5 5 5 0 HEAT-like repeat PCRF PF03462.13 EEB07536.1 - 0.039 13.6 0.8 0.11 12.1 0.6 1.8 1 0 0 1 1 1 0 PCRF domain DUF2435 PF10363.4 EEB07536.1 - 0.046 13.6 0.0 2.4 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) DUF3437 PF11919.3 EEB07537.1 - 1.1e-23 82.6 0.0 4.7e-23 80.7 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 EEB07537.1 - 0.03 14.5 9.2 0.31 11.3 0.2 5.0 5 1 1 6 6 6 0 HEAT repeats HEAT PF02985.17 EEB07537.1 - 0.77 9.9 5.9 4 7.7 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Pil1 PF13805.1 EEB07538.1 - 2.5e-143 476.1 0.5 3.4e-143 475.6 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2043 PF09740.4 EEB07538.1 - 0.15 12.1 0.7 2.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) DNA_primase_lrg PF04104.9 EEB07539.1 - 8.4e-78 261.2 0.0 1.2e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PCI PF01399.22 EEB07540.2 - 2.9e-07 30.7 0.5 6.8e-06 26.3 0.0 3.3 2 1 0 2 2 2 1 PCI domain DASH_Dam1 PF08653.5 EEB07540.2 - 2.3 8.0 4.6 0.6 9.9 0.1 2.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 zf-HC5HC2H_2 PF13832.1 EEB07541.1 - 7.4e-27 93.5 20.5 1.5e-26 92.4 9.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEB07541.1 - 7.9e-23 80.4 7.1 7.9e-23 80.4 4.9 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EEB07541.1 - 1.7e-13 49.6 3.0 1.7e-13 49.6 2.1 3.6 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EEB07541.1 - 1.1e-08 34.6 11.2 1.1e-08 34.6 7.8 3.3 4 0 0 4 4 4 2 PHD-finger EPL1 PF10513.4 EEB07541.1 - 1.5e-08 35.0 4.3 5.2e-08 33.2 3.0 1.9 1 1 0 1 1 1 1 Enhancer of polycomb-like Dehyd-heme_bind PF09098.5 EEB07541.1 - 0.0097 15.3 0.3 1.1 8.6 0.2 2.5 2 0 0 2 2 2 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Gal4_dimer PF03902.8 EEB07541.1 - 0.019 14.9 0.2 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain zf-RING-like PF08746.6 EEB07541.1 - 0.098 12.6 22.9 0.025 14.5 4.7 3.0 2 1 0 2 2 2 0 RING-like domain CMD PF02627.15 EEB07542.1 - 4.3e-08 32.8 0.0 6.1e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2475 PF10629.4 EEB07542.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) zf-rbx1 PF12678.2 EEB07543.2 - 3e-11 43.2 1.0 7.1e-11 42.0 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEB07543.2 - 8.6e-10 38.2 11.5 1.1e-09 37.9 5.8 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB07543.2 - 8.5e-08 31.7 6.9 1.4e-06 27.9 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB07543.2 - 2.7e-07 30.1 0.8 7.6e-07 28.6 0.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07543.2 - 5.2e-07 29.2 4.8 4.3e-06 26.3 3.5 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEB07543.2 - 3.3e-06 27.0 2.1 3.3e-06 27.0 1.5 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB07543.2 - 0.00016 21.2 5.5 0.00021 20.9 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EEB07543.2 - 0.0028 17.4 4.0 0.012 15.3 2.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EEB07543.2 - 0.014 14.8 0.4 0.036 13.6 0.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EEB07543.2 - 0.17 11.7 4.5 0.071 12.9 0.9 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF2306 PF10067.4 EEB07543.2 - 0.44 10.7 6.6 0.19 11.8 2.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) RINGv PF12906.2 EEB07543.2 - 1.1 9.2 7.3 0.53 10.3 2.2 2.3 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EEB07543.2 - 1.8 8.5 5.9 22 5.0 4.1 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEB07543.2 - 2.6 7.7 7.9 0.17 11.4 0.7 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EEB07543.2 - 9 5.8 8.1 2.7 7.5 2.6 2.2 2 0 0 2 2 2 0 P-11 zinc finger Gcd10p PF04189.8 EEB07545.1 - 6.8e-79 265.0 0.1 4.3e-78 262.4 0.1 1.9 1 1 0 1 1 1 1 Gcd10p family LSM14 PF12701.2 EEB07546.1 - 6.1e-33 112.5 0.0 6.1e-33 112.5 0.0 1.9 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 EEB07546.1 - 6.3e-10 39.5 3.7 8.8e-09 35.8 0.2 4.1 3 1 1 4 4 4 2 FDF domain SM-ATX PF14438.1 EEB07546.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Ras PF00071.17 EEB07548.2 - 4.1e-66 221.3 0.4 5e-66 221.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB07548.2 - 9.2e-23 81.0 0.2 1.7e-22 80.1 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EEB07548.2 - 2e-17 62.9 0.2 2.4e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB07548.2 - 2.3e-06 26.9 0.1 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEB07548.2 - 2.8e-06 26.9 0.2 6.1e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEB07548.2 - 1.6e-05 24.2 0.0 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEB07548.2 - 3.6e-05 23.7 0.1 5.9e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEB07548.2 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EEB07548.2 - 0.00066 19.8 0.0 0.07 13.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EEB07548.2 - 0.0015 17.8 0.0 0.013 14.7 0.0 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEB07548.2 - 0.012 14.7 0.1 0.055 12.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEB07548.2 - 0.018 15.0 0.1 0.072 13.0 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EEB07548.2 - 0.025 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EEB07548.2 - 0.039 13.4 0.1 1 8.8 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EEB07548.2 - 0.042 12.8 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 EEB07548.2 - 0.045 13.4 0.1 0.1 12.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EEB07548.2 - 0.062 13.6 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EEB07548.2 - 0.083 11.5 4.8 1.2 7.7 0.5 2.9 1 1 1 2 2 2 0 G-protein alpha subunit OPA3 PF07047.7 EEB07549.1 - 1.3e-36 125.3 0.5 2.1e-36 124.6 0.3 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) ZapA PF05164.8 EEB07549.1 - 0.015 15.2 0.9 0.48 10.4 0.1 2.5 3 0 0 3 3 3 0 Cell division protein ZapA DAP3 PF10236.4 EEB07550.1 - 9.7e-69 231.6 0.1 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 EEB07550.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RRS1 PF04939.7 EEB07551.1 - 6.1e-54 181.9 0.6 6.8e-54 181.7 0.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF4230 PF14014.1 EEB07551.1 - 0.099 12.4 0.6 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) RhoGEF PF00621.15 EEB07552.1 - 4.2e-26 91.9 1.4 2.5e-25 89.3 0.1 2.6 3 1 0 3 3 3 1 RhoGEF domain Cytochrom_C1 PF02167.10 EEB07553.1 - 9.5e-78 260.8 0.0 1.2e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EEB07553.1 - 0.00021 21.3 0.0 0.00075 19.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EEB07553.1 - 0.0026 18.5 0.0 0.17 12.7 0.1 2.4 2 0 0 2 2 2 1 Cytochrome c DUF3068 PF11271.3 EEB07553.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Lactonase PF10282.4 EEB07554.1 - 3.1e-60 204.0 0.0 3.4e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EEB07554.1 - 0.065 13.2 2.8 0.39 10.7 0.1 3.2 3 0 0 3 3 3 0 NHL repeat PMI_typeI PF01238.16 EEB07555.1 - 5.6e-118 394.1 0.0 7e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Frataxin_Cyay PF01491.11 EEB07555.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Frataxin-like domain SUN PF03856.8 EEB07556.2 - 1.5e-94 315.9 14.4 1.9e-94 315.6 10.0 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF3508 PF12018.3 EEB07556.2 - 0.22 10.4 0.0 0.48 9.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) WD40 PF00400.27 EEB07557.2 - 2.5e-56 185.6 22.1 7.8e-12 44.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EEB07557.2 - 7.3e-08 32.0 1.8 1.7e-07 30.8 1.2 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EEB07557.2 - 4e-07 28.5 13.9 0.14 10.2 0.1 5.9 2 1 4 7 7 7 4 Nucleoporin Nup120/160 F-box PF00646.28 EEB07557.2 - 4.1e-06 26.2 0.6 1.3e-05 24.7 0.4 1.9 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EEB07557.2 - 6.6e-05 22.4 3.1 0.41 10.0 0.9 3.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EEB07557.2 - 0.0038 17.4 0.2 12 6.2 0.1 4.0 3 0 0 3 3 3 1 PQQ-like domain PRANC PF09372.5 EEB07557.2 - 0.036 14.0 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 PRANC domain PHD PF00628.24 EEB07558.1 - 1.5e-05 24.6 11.6 4.1e-05 23.1 8.0 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB07558.1 - 0.0013 17.9 4.5 0.0048 16.1 3.1 2.0 1 0 0 1 1 1 1 PHD-finger HORMA PF02301.13 EEB07558.1 - 0.0035 16.8 3.5 0.011 15.2 2.2 1.9 1 1 0 1 1 1 1 HORMA domain RNA_polI_A14 PF08203.6 EEB07559.1 - 6.3e-16 58.3 1.0 2.4e-15 56.5 0.0 2.2 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 DUF755 PF05501.6 EEB07559.1 - 0.0025 17.8 4.3 0.0033 17.4 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) YjgP_YjgQ PF03739.9 EEB07559.1 - 0.028 13.1 0.6 0.034 12.9 0.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RNase_H2-Ydr279 PF09468.5 EEB07559.1 - 0.11 11.7 6.6 0.11 11.6 4.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 EEB07559.1 - 0.26 11.3 11.5 0.33 10.9 8.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Metal_resist PF13801.1 EEB07559.1 - 1.4 8.9 5.6 1.9 8.5 3.9 1.2 1 0 0 1 1 1 0 Heavy-metal resistance CDC45 PF02724.9 EEB07559.1 - 1.7 6.5 9.7 1.8 6.4 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EEB07559.1 - 2.3 8.0 11.5 3 7.6 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EEB07559.1 - 2.5 5.6 7.0 2.7 5.6 4.8 1.0 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 EEB07559.1 - 5.4 5.6 14.9 6.4 5.4 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Acyltransferase PF01553.16 EEB07560.1 - 4.7e-12 45.4 0.0 4e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.11 EEB07561.1 - 1.5e-44 151.2 0.0 1.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FeoA PF04023.9 EEB07561.1 - 0.099 12.6 0.2 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 FeoA domain Dynamin_N PF00350.18 EEB07562.1 - 1.5e-40 138.8 0.0 1.5e-40 138.8 0.0 2.8 4 0 0 4 4 4 1 Dynamin family Dynamin_M PF01031.15 EEB07562.1 - 2e-11 43.2 4.3 2.7e-10 39.5 0.1 2.9 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EEB07562.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEB07562.1 - 0.0013 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EEB07562.1 - 0.0053 16.7 0.5 0.23 11.4 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.4 EEB07562.1 - 0.0093 15.4 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EEB07562.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EEB07562.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PH PF00169.24 EEB07563.1 - 3e-18 65.9 0.5 4.8e-08 33.1 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EEB07563.1 - 0.0001 22.5 4.7 0.088 13.0 0.7 3.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 EEB07563.1 - 0.00039 20.4 0.1 0.076 13.0 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EEB07563.1 - 0.0049 16.7 1.3 0.091 12.6 0.1 2.6 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 EEB07563.1 - 0.0093 16.1 1.0 3.2 7.9 0.0 3.0 2 2 0 2 2 2 2 Pleckstrin homology domain DNA_pol_A PF00476.15 EEB07564.1 - 2.2e-93 312.9 0.0 3.2e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EEB07564.1 - 0.026 13.9 2.0 0.85 9.0 1.4 2.4 1 1 0 1 1 1 0 3'-5' exonuclease zf-MYND PF01753.13 EEB07565.1 - 6e-08 32.4 21.7 6e-08 32.4 15.0 2.3 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EEB07565.1 - 0.00057 20.2 0.1 0.0022 18.3 0.1 2.1 1 1 0 1 1 1 1 SET domain PG_binding_1 PF01471.13 EEB07565.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF3844 PF12955.2 EEB07565.1 - 0.7 10.0 11.9 0.27 11.3 2.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) LCM PF04072.9 EEB07566.1 - 2.4e-20 72.8 0.0 4.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Xpo1 PF08389.7 EEB07567.1 - 7e-34 116.8 1.6 1e-32 113.0 0.0 3.6 3 1 0 3 3 3 1 Exportin 1-like protein NUC130_3NT PF08158.7 EEB07567.1 - 0.015 15.5 0.1 24 5.2 0.0 4.2 3 0 0 3 3 3 0 NUC130/3NT domain HEAT_EZ PF13513.1 EEB07567.1 - 0.036 14.5 0.0 61 4.2 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat U3_snoRNA_assoc PF08297.6 EEB07568.1 - 2.9e-07 30.6 3.2 2.9e-07 30.6 2.2 2.3 1 1 1 2 2 2 1 U3 snoRNA associated DUF572 PF04502.8 EEB07568.1 - 0.021 14.0 14.2 0.028 13.6 9.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) HTH_1 PF00126.22 EEB07568.1 - 0.025 14.2 0.7 0.13 12.0 0.8 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SNAPc19 PF15497.1 EEB07568.1 - 0.054 13.7 12.5 0.13 12.4 8.6 1.7 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Spt5_N PF11942.3 EEB07568.1 - 0.33 11.5 19.4 0.47 11.0 3.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BTV_NS2 PF04514.7 EEB07568.1 - 1.4 7.6 9.7 1.6 7.5 6.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Striatin PF08232.7 EEB07568.1 - 8.7 6.6 14.7 3.3 8.0 8.1 1.9 1 1 1 2 2 2 0 Striatin family HSP70 PF00012.15 EEB07568.1 - 8.9 4.0 12.2 11 3.7 8.4 1.1 1 0 0 1 1 1 0 Hsp70 protein NTF2 PF02136.15 EEB07569.1 - 1.9e-20 73.4 0.6 3.6e-18 66.0 0.0 2.4 1 1 1 2 2 2 2 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 EEB07569.1 - 1.3e-06 28.3 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB07569.1 - 3.4e-05 23.4 0.0 6.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07569.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-H PF05837.7 EEB07570.1 - 3.9e-11 43.0 1.0 3.9e-11 43.0 0.7 2.2 2 1 0 2 2 2 1 Centromere protein H (CENP-H) PilJ PF13675.1 EEB07570.1 - 0.00087 19.5 0.9 0.063 13.5 0.2 2.6 2 1 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Phage_T7_tail PF03906.9 EEB07570.1 - 0.013 15.1 0.1 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Phage T7 tail fibre protein DUF2265 PF10023.4 EEB07570.1 - 0.086 11.9 0.4 0.13 11.3 0.1 1.4 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) Vac7 PF12751.2 EEB07571.1 - 1.6e-11 43.7 7.3 2.8e-11 42.9 5.1 1.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 P5-ATPase PF12409.3 EEB07571.1 - 3.5 7.5 9.1 1.1 9.1 3.6 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter RabGAP-TBC PF00566.13 EEB07572.1 - 4.4e-51 173.3 1.8 7e-51 172.7 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol_E_B PF04042.11 EEB07573.1 - 3.1e-51 173.5 0.5 4.8e-51 172.9 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DWNN PF08783.6 EEB07574.1 - 3.4e-33 113.4 0.2 5.6e-33 112.7 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EEB07574.1 - 0.00012 21.5 5.3 0.00031 20.1 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEB07574.1 - 0.00098 18.9 1.7 0.00098 18.9 1.2 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EEB07574.1 - 0.0049 16.8 12.2 0.0049 16.8 8.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 EEB07574.1 - 0.018 14.6 2.5 0.033 13.7 1.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-CCHC_3 PF13917.1 EEB07574.1 - 0.022 14.4 0.2 0.022 14.4 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.20 EEB07574.1 - 0.055 13.1 12.6 0.11 12.1 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07574.1 - 0.37 10.5 18.4 0.023 14.4 8.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.1 EEB07574.1 - 0.42 10.4 3.5 0.98 9.2 2.1 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EEB07574.1 - 0.48 10.0 10.5 1.1 8.8 7.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EEB07574.1 - 0.7 9.6 16.4 0.05 13.2 7.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 EEB07574.1 - 2.3 8.0 11.0 2.6 7.9 1.1 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_2 PF13639.1 EEB07574.1 - 2.4 8.0 16.2 0.075 12.8 6.9 1.8 2 0 0 2 2 2 0 Ring finger domain zf-CCHC_5 PF14787.1 EEB07574.1 - 3.3 7.2 7.2 2.3 7.7 0.3 2.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DEAD PF00270.24 EEB07575.2 - 8.7e-46 155.4 0.0 1.5e-44 151.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07575.2 - 1.3e-28 98.6 0.0 1.1e-27 95.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB07575.2 - 0.00016 21.5 0.0 0.0014 18.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEB07575.2 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_30 PF13604.1 EEB07575.2 - 0.01 15.3 0.0 0.12 11.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain CRF1 PF10380.4 EEB07576.1 - 7.1e-08 32.8 1.1 7.1e-08 32.8 0.7 1.9 2 0 0 2 2 2 1 Transcription factor CRF1 UreE_N PF02814.10 EEB07576.1 - 0.057 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain LRR_4 PF12799.2 EEB07577.1 - 2.8e-11 42.7 35.1 5.7e-07 29.0 4.4 6.7 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB07577.1 - 1.1e-09 37.8 27.3 2.1e-06 27.3 3.3 5.3 5 1 1 6 6 6 3 Leucine rich repeat LRR_9 PF14580.1 EEB07577.1 - 1.6e-08 34.2 9.2 3.3e-06 26.7 1.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EEB07577.1 - 0.0073 16.2 23.7 0.3 11.2 0.9 7.2 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EEB07577.1 - 0.014 15.4 19.1 2.8 8.5 1.0 7.7 7 1 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 EEB07577.1 - 0.024 14.5 25.2 0.8 9.9 0.3 7.6 7 1 0 7 7 7 0 Leucine Rich Repeat DUF2009 PF09418.5 EEB07578.1 - 1.2e-204 680.2 0.3 1.5e-204 680.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Jacalin PF01419.12 EEB07579.1 - 0.095 12.5 0.5 0.31 10.9 0.4 1.8 1 1 0 1 1 1 0 Jacalin-like lectin domain Flagellin_D3 PF08884.6 EEB07581.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellin D3 domain Y_Y_Y PF07495.8 EEB07581.1 - 0.15 11.8 1.3 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Y_Y_Y domain Pyrophosphatase PF00719.14 EEB07582.1 - 5.6e-52 175.3 0.1 7.1e-52 174.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PNK3P PF08645.6 EEB07583.1 - 1.8e-53 180.2 0.0 5.1e-53 178.7 0.0 1.8 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EEB07583.1 - 2.5e-26 92.2 0.1 1e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEB07583.1 - 3.2e-05 23.2 0.8 0.0023 17.1 0.6 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EEB07583.1 - 5.8e-05 22.2 0.0 0.00072 18.7 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EEB07583.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEB07583.1 - 0.022 14.7 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.6 EEB07583.1 - 0.043 13.6 0.1 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain 6PF2K PF01591.13 EEB07583.1 - 0.052 12.6 0.0 1.8 7.5 0.0 2.2 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Mpp10 PF04006.7 EEB07584.1 - 2.3e-139 465.5 57.2 3.2e-139 465.0 39.6 1.2 1 0 0 1 1 1 1 Mpp10 protein DUF4055 PF13264.1 EEB07584.1 - 3.2 7.8 6.6 0.55 10.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Ribosom_S12_S23 PF00164.20 EEB07585.1 - 5.8e-40 135.5 0.6 6.9e-40 135.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ICE2 PF08426.5 EEB07586.1 - 1.8e-92 310.1 27.8 2.3e-92 309.7 19.3 1.1 1 0 0 1 1 1 1 ICE2 Ras PF00071.17 EEB07587.1 - 3e-56 189.2 0.0 3.6e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB07587.1 - 1.3e-15 57.9 0.0 2.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB07587.1 - 5.6e-07 28.9 0.0 7.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEB07587.1 - 0.0002 20.6 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EEB07587.1 - 0.00054 19.4 0.0 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEB07587.1 - 0.028 13.5 0.0 0.034 13.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEB07587.1 - 0.073 12.5 0.0 11 5.5 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ufd2P_core PF10408.4 EEB07588.1 - 2.5e-182 607.4 13.1 3.2e-182 607.0 9.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EEB07588.1 - 5.4e-29 99.9 0.6 5.4e-29 99.9 0.4 2.5 3 0 0 3 3 3 1 U-box domain HA2 PF04408.18 EEB07589.1 - 1.9e-19 69.5 0.0 3.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEB07589.1 - 4.1e-13 48.9 0.0 1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEB07589.1 - 1.6e-11 43.9 0.1 3.6e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EEB07589.1 - 5.2e-06 26.6 0.2 1.5e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEB07589.1 - 0.00019 20.9 0.1 0.00048 19.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EEB07589.1 - 0.00088 19.1 0.1 0.011 15.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EEB07589.1 - 0.012 14.7 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EEB07589.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEB07589.1 - 0.019 15.2 0.1 0.057 13.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 EEB07589.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_2 PF12756.2 EEB07589.1 - 0.034 14.2 0.2 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_23 PF13476.1 EEB07589.1 - 0.038 14.3 0.2 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EEB07589.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EEB07589.1 - 0.099 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 EEB07589.1 - 0.13 12.8 0.1 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF1604 PF07713.8 EEB07591.1 - 1.1e-33 114.9 0.1 3.3e-33 113.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch_2 PF12656.2 EEB07591.1 - 0.0041 16.9 0.2 0.18 11.6 0.2 2.6 1 1 0 1 1 1 1 DExH-box splicing factor binding site Aldolase_II PF00596.16 EEB07592.1 - 2.4e-42 144.6 0.0 2.8e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GDI PF00996.13 EEB07592.1 - 0.015 13.6 0.0 0.02 13.2 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor ResIII PF04851.10 EEB07593.1 - 2.3e-21 76.4 0.3 2.1e-20 73.3 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEB07593.1 - 1.3e-18 66.6 0.3 6.5e-18 64.3 0.2 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB07593.1 - 1.3e-15 57.2 0.0 6.2e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EEB07593.1 - 0.00019 20.3 0.0 0.00072 18.4 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EEB07593.1 - 0.038 14.1 0.0 0.65 10.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain TFIIS_M PF07500.9 EEB07594.1 - 2.7e-31 108.0 1.3 2.7e-31 108.0 0.9 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EEB07594.1 - 1.7e-18 65.9 9.2 1.7e-18 65.9 6.4 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EEB07594.1 - 6.1e-13 48.0 0.8 2e-12 46.4 0.5 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EEB07594.1 - 0.018 14.7 2.9 0.045 13.4 2.0 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LEDGF PF11467.3 EEB07594.1 - 0.019 14.6 0.8 0.019 14.6 0.5 1.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) FUSC PF04632.7 EEB07594.1 - 0.17 10.2 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SET PF00856.23 EEB07594.1 - 1.8 8.8 5.1 4.4 7.5 3.5 1.8 1 1 0 1 1 1 0 SET domain SET PF00856.23 EEB07595.1 - 3.5e-09 37.1 0.0 9.3e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 SET domain Peroxin-13_N PF04088.8 EEB07596.1 - 3.8e-30 104.9 0.0 6.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 EEB07596.1 - 2.9e-12 45.9 0.0 1.3e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEB07596.1 - 7.6e-10 38.1 0.0 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEB07596.1 - 9.2e-10 37.7 0.0 2.5e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain Calreticulin PF00262.13 EEB07597.1 - 4.6e-151 502.6 0.3 6.5e-151 502.1 0.2 1.2 1 0 0 1 1 1 1 Calreticulin family CAP_GLY PF01302.20 EEB07598.1 - 8.7e-18 63.8 1.2 1.4e-17 63.1 0.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain Glu-tRNAGln PF02686.10 EEB07598.1 - 0.036 13.8 1.3 4.8 7.0 0.6 2.6 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF1993 PF09351.5 EEB07598.1 - 0.19 11.6 8.9 1.8 8.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) Phage_GP20 PF06810.6 EEB07598.1 - 0.23 10.8 13.6 0.051 13.0 2.4 3.2 2 2 1 3 3 3 0 Phage minor structural protein GP20 GAS PF13851.1 EEB07598.1 - 2.3 7.3 27.5 0.19 10.8 11.4 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 EEB07598.1 - 3.4 7.4 10.4 17 5.2 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EEB07598.1 - 3.7 7.0 27.9 0.3 10.6 2.6 3.3 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1492 PF07374.6 EEB07598.1 - 5.1 7.2 7.1 1.5 8.9 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1492) DUF641 PF04859.7 EEB07598.1 - 9.1 6.0 19.0 0.35 10.6 0.6 3.6 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.1 EEB07598.1 - 9.4 5.6 32.5 0.29 10.5 2.5 3.7 2 2 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease G6PD_C PF02781.11 EEB07599.2 - 4.6e-78 262.0 0.0 7.2e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEB07599.2 - 5.2e-42 144.1 0.0 9.8e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FMN_red PF03358.10 EEB07600.2 - 8e-09 35.1 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EEB07600.2 - 1.3e-05 25.1 0.2 3.7e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EEB07600.2 - 5.5e-05 22.7 0.5 0.00015 21.3 0.1 1.8 1 1 1 2 2 2 1 Flavodoxin-like fold SNF2_N PF00176.18 EEB07601.2 - 1.5e-59 201.2 0.0 2.3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEB07601.2 - 1.1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Atg14 PF10186.4 EEB07602.1 - 6.9e-06 25.2 24.5 0.00021 20.3 16.6 2.4 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-HC5HC2H PF13771.1 EEB07602.1 - 0.046 13.8 2.1 0.11 12.6 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain ACCA PF03255.9 EEB07602.1 - 9.7 5.7 7.5 1.9 8.0 1.1 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit F_actin_cap_B PF01115.12 EEB07603.1 - 3.8e-91 304.5 0.1 4.5e-91 304.3 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Bromodomain PF00439.20 EEB07604.1 - 3.7e-47 158.1 0.5 7.6e-24 83.4 0.1 2.7 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EEB07605.1 - 2.9e-16 59.3 0.1 6.2e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family TFIIA PF03153.8 EEB07605.1 - 0.0004 20.3 9.3 0.00084 19.3 6.4 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2407_C PF13373.1 EEB07606.1 - 5.9e-21 74.8 5.6 1e-19 70.8 3.9 2.1 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EEB07606.1 - 6.2e-16 58.3 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Lant_dehyd_C PF04738.8 EEB07606.1 - 0.14 10.3 0.0 5.1 5.2 0.1 2.1 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus ABC_tran PF00005.22 EEB07607.1 - 2.4e-55 186.5 1.5 5.6e-33 114.1 0.0 4.0 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EEB07607.1 - 2e-19 70.6 0.3 6.4e-07 29.6 0.1 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EEB07607.1 - 9.2e-14 51.1 0.0 0.00054 19.2 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EEB07607.1 - 9.7e-10 37.9 0.3 2.4e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.1 EEB07607.1 - 2.5e-08 33.4 0.9 0.037 13.0 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EEB07607.1 - 1.1e-07 32.6 0.0 0.0083 16.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEB07607.1 - 3.2e-07 30.1 0.2 0.08 12.6 0.0 3.7 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EEB07607.1 - 3.2e-07 30.8 0.0 0.034 14.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEB07607.1 - 5e-07 29.1 0.5 0.0087 15.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEB07607.1 - 5.1e-07 29.6 0.0 0.03 14.2 0.0 3.4 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EEB07607.1 - 1.2e-06 27.7 0.1 0.0052 15.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EEB07607.1 - 1.1e-05 25.2 0.0 0.043 13.4 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 EEB07607.1 - 1.2e-05 25.4 3.8 0.009 16.1 0.0 4.3 5 0 0 5 5 2 1 AAA domain AAA_25 PF13481.1 EEB07607.1 - 1.3e-05 24.6 0.1 0.11 11.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EEB07607.1 - 2.2e-05 24.5 0.8 0.39 10.6 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EEB07607.1 - 3.5e-05 24.2 12.4 0.062 13.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EEB07607.1 - 4.4e-05 23.0 0.6 0.2 11.0 0.1 4.0 4 0 0 4 4 4 1 AAA-like domain RNA_helicase PF00910.17 EEB07607.1 - 6.6e-05 23.0 0.1 0.68 10.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.1 EEB07607.1 - 8.4e-05 22.5 0.0 0.43 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EEB07607.1 - 0.00021 20.1 0.2 0.27 9.9 0.1 2.5 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 EEB07607.1 - 0.00029 20.6 0.0 0.37 10.7 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EEB07607.1 - 0.00042 20.2 3.6 0.0098 15.7 0.3 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EEB07607.1 - 0.00042 20.1 0.1 1.4 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EEB07607.1 - 0.00049 20.0 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EEB07607.1 - 0.00055 19.7 1.0 0.16 11.7 0.0 3.7 5 0 0 5 5 3 1 Dynamin family Viral_helicase1 PF01443.13 EEB07607.1 - 0.00062 19.3 0.1 1.7 8.0 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EEB07607.1 - 0.00063 19.3 0.4 0.024 14.1 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EEB07607.1 - 0.00069 19.1 0.4 0.39 10.1 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family CLASP_N PF12348.3 EEB07607.1 - 0.0011 18.4 2.1 0.098 11.9 0.1 3.2 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.17 EEB07607.1 - 0.0016 18.3 2.6 8.4 6.7 0.0 4.8 5 0 0 5 5 4 0 HEAT repeat AAA PF00004.24 EEB07607.1 - 0.0016 18.6 0.0 3.4 7.8 0.0 3.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Adaptin_N PF01602.15 EEB07607.1 - 0.0021 16.4 2.8 0.0085 14.4 0.2 2.2 1 1 1 2 2 2 2 Adaptin N terminal region ComC PF03047.9 EEB07607.1 - 0.0055 16.0 1.9 0.013 14.9 1.3 1.7 1 0 0 1 1 1 1 COMC family AAA_19 PF13245.1 EEB07607.1 - 0.014 15.1 0.4 0.55 10.0 0.2 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EEB07607.1 - 0.022 14.3 0.1 7.1 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EEB07607.1 - 0.024 13.5 0.1 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EEB07607.1 - 0.025 14.9 0.0 3.2 8.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EEB07607.1 - 0.025 14.0 0.0 8.8 5.7 0.1 3.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEB07607.1 - 0.027 14.1 0.3 9.4 5.9 0.1 3.5 4 0 0 4 4 3 0 NTPase GTP_EFTU PF00009.22 EEB07607.1 - 0.033 13.6 0.1 9.2 5.6 0.0 3.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_13 PF13166.1 EEB07607.1 - 0.052 12.0 4.3 4.2 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EEB07607.1 - 0.052 13.2 6.9 1.1 8.9 0.0 3.4 4 0 0 4 4 2 0 Archaeal ATPase AAA_24 PF13479.1 EEB07607.1 - 0.057 12.9 1.0 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EEB07607.1 - 0.062 12.7 0.0 10 5.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 EEB07607.1 - 0.12 11.0 0.0 5.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein HEAT_EZ PF13513.1 EEB07607.1 - 1.3 9.6 10.6 5.8 7.5 0.0 5.0 5 2 0 5 5 4 0 HEAT-like repeat ATE_C PF04377.10 EEB07608.2 - 5.8e-46 155.7 5.1 1.3e-45 154.5 3.5 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EEB07608.2 - 3.7e-24 84.3 3.7 8.7e-24 83.1 1.6 2.2 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EEB07608.2 - 0.031 14.2 0.6 0.068 13.1 0.4 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Syja_N PF02383.13 EEB07609.2 - 2.2e-76 256.6 0.0 3e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Pil1 PF13805.1 EEB07610.1 - 2.5e-108 361.3 1.0 3.4e-54 183.8 0.1 2.2 1 1 1 2 2 2 2 Eisosome component PIL1 AAA_25 PF13481.1 EEB07611.1 - 1.1e-09 37.9 0.0 8e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 EEB07611.1 - 8.4e-09 34.9 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEB07611.1 - 2.8e-06 26.6 0.2 8e-06 25.1 0.0 1.8 2 1 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 EEB07611.1 - 5e-06 26.0 0.1 1.2e-05 24.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEB07611.1 - 2.5e-05 24.1 0.0 5.9e-05 22.8 0.0 1.5 1 1 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EEB07611.1 - 4.8e-05 22.9 0.0 7.5e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 EEB07611.1 - 0.00031 20.4 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEB07611.1 - 0.0004 20.5 0.1 0.001 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EEB07611.1 - 0.00059 18.8 0.0 0.57 9.0 0.0 2.7 3 1 0 3 3 3 2 Rad51 AAA_17 PF13207.1 EEB07611.1 - 0.00071 20.3 0.0 0.0015 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB07611.1 - 0.00092 19.5 0.2 0.0021 18.3 0.2 1.8 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EEB07611.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EEB07611.1 - 0.0028 17.5 0.4 0.012 15.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain CbiA PF01656.18 EEB07611.1 - 0.0042 16.5 0.2 0.0056 16.1 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 EEB07611.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 EEB07611.1 - 0.01 16.0 0.5 0.057 13.6 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEB07611.1 - 0.013 15.4 0.0 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain CAML PF14963.1 EEB07611.1 - 0.015 14.6 0.4 0.024 14.0 0.3 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand NB-ARC PF00931.17 EEB07611.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EEB07611.1 - 0.026 14.8 0.2 0.068 13.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEB07611.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEB07611.1 - 0.03 14.3 0.1 0.049 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EEB07611.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.10 EEB07611.1 - 0.047 12.5 2.1 0.51 9.1 0.3 2.7 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain CobA_CobO_BtuR PF02572.10 EEB07611.1 - 0.055 13.1 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_35 PF14516.1 EEB07611.1 - 0.056 12.0 0.0 0.091 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 EEB07611.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 NTPase Helicase_RecD PF05127.9 EEB07611.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Helicase DUF258 PF03193.11 EEB07611.1 - 0.11 11.6 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EEB07611.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EEB07611.1 - 0.13 11.8 0.1 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EEB07611.1 - 0.14 11.7 0.2 0.29 10.6 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.13 EEB07612.1 - 3.4e-31 108.0 0.1 7.1e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB07612.1 - 7.1e-09 35.4 8.5 1.5e-08 34.4 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 EEB07614.1 - 9.4e-43 147.0 1.1 1.2e-42 146.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.6 EEB07614.1 - 0.00058 18.9 0.4 2.8 6.8 0.0 3.5 3 1 0 3 3 3 3 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pkinase PF00069.20 EEB07615.1 - 6.1e-59 199.2 0.0 9.5e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07615.1 - 1.9e-29 102.5 0.0 7.2e-29 100.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase 6PF2K PF01591.13 EEB07616.1 - 6.4e-42 143.1 0.4 2.6e-40 137.8 0.3 2.1 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEB07616.1 - 3.8e-30 105.0 0.0 1.1e-29 103.6 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EEB07616.1 - 0.0021 18.8 0.2 0.032 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EEB07616.1 - 0.018 14.2 0.0 0.038 13.2 0.0 1.5 1 1 1 2 2 2 0 Chromatin associated protein KTI12 His_Phos_2 PF00328.17 EEB07616.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BRICHOS PF04089.9 EEB07616.1 - 0.093 12.6 0.1 0.42 10.5 0.1 2.0 2 0 0 2 2 2 0 BRICHOS domain DUF726 PF05277.7 EEB07618.1 - 2.1e-113 378.7 0.3 3.1e-113 378.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EEB07618.1 - 0.0011 18.8 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB07618.1 - 0.0045 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.6 EEB07618.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_5 PF12695.2 EEB07618.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family CLN3 PF02487.12 EEB07619.1 - 2.6e-74 250.4 24.0 3.6e-71 240.0 16.6 2.1 1 1 0 1 1 1 1 CLN3 protein DUF3481 PF11980.3 EEB07619.1 - 3.1 7.6 4.9 1.7 8.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Steroid_dh PF02544.11 EEB07620.2 - 1.1e-42 145.3 7.9 1.1e-42 145.3 5.5 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EEB07620.2 - 2.8e-07 29.8 0.0 4.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 EEB07620.2 - 0.00062 19.8 0.5 0.00062 19.8 0.4 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EEB07620.2 - 0.0027 17.0 2.1 0.0027 17.0 1.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Glyco_hydro_71 PF03659.9 EEB07621.2 - 1.6e-99 333.0 6.8 1.8e-99 332.8 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SQS_PSY PF00494.14 EEB07622.1 - 6.2e-38 130.6 0.0 1e-37 129.9 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4519 PF15012.1 EEB07622.1 - 0.027 14.3 1.4 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 60KD_IMP PF02096.15 EEB07622.1 - 0.045 13.3 2.4 0.14 11.8 0.1 2.2 2 1 0 2 2 2 0 60Kd inner membrane protein PAP_central PF04928.12 EEB07623.1 - 2.2e-108 360.8 0.0 2.9e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EEB07623.1 - 2.1e-49 167.0 0.2 2.1e-49 167.0 0.2 1.6 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEB07623.1 - 1.3e-10 41.4 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Amidase PF01425.16 EEB07624.1 - 1.7e-112 376.5 0.0 2e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 Amidase AAA_12 PF13087.1 EEB07625.2 - 1.3e-12 47.5 0.0 1.5e-10 40.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEB07625.2 - 0.00038 21.2 0.0 0.0011 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB07625.2 - 0.00095 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EEB07625.2 - 0.0023 18.2 0.1 0.017 15.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EEB07625.2 - 0.0023 17.5 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEB07625.2 - 0.0044 15.9 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EEB07625.2 - 0.0087 16.0 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEB07625.2 - 0.012 15.7 0.0 0.058 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEB07625.2 - 0.032 14.5 0.0 0.18 12.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEB07625.2 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EEB07625.2 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase FAT PF02259.18 EEB07626.1 - 2.5e-125 418.1 8.9 2.5e-125 418.1 6.2 2.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EEB07626.1 - 4.6e-63 212.8 0.3 8.3e-63 211.9 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EEB07626.1 - 3.8e-59 199.1 7.9 1.4e-58 197.3 0.2 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EEB07626.1 - 9.6e-44 147.5 0.8 5.7e-43 145.0 0.0 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EEB07626.1 - 2.8e-18 65.9 16.8 3.7e-05 23.9 0.0 10.3 10 1 3 13 13 12 5 HEAT repeats FATC PF02260.15 EEB07626.1 - 3.5e-16 58.3 0.3 8.9e-16 57.0 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EEB07626.1 - 5.2e-13 47.8 15.0 0.049 13.7 0.0 10.8 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EEB07626.1 - 4.3e-09 36.5 19.5 2e-05 24.8 0.0 10.5 12 1 1 13 13 10 1 HEAT-like repeat Apc3 PF12895.2 EEB07626.1 - 0.002 18.2 2.0 0.37 10.9 0.1 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB07626.1 - 0.008 16.0 0.7 62 3.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3518 PF12031.3 EEB07626.1 - 0.012 14.4 2.4 0.23 10.2 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3518) TPR_16 PF13432.1 EEB07626.1 - 0.044 14.4 1.6 7.6 7.3 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEB07626.1 - 0.23 11.3 2.4 6.6 6.7 0.2 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Myco_arth_vir_N PF09610.5 EEB07626.1 - 2.2 8.3 4.8 6.8 6.7 3.3 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) TPR_2 PF07719.12 EEB07626.1 - 4.1 7.5 8.0 18 5.5 0.6 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TIMELESS PF04821.9 EEB07627.1 - 2.1e-54 184.5 1.5 2.1e-54 184.5 1.1 2.6 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 EEB07627.1 - 1.1e-14 54.2 0.0 1.1e-14 54.2 0.0 3.8 5 0 0 5 5 5 1 Timeless protein C terminal region gpD PF02925.11 EEB07627.1 - 0.073 12.8 0.2 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage scaffolding protein D PAP_assoc PF03828.14 EEB07628.1 - 1.1e-13 50.8 0.0 2.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB07628.1 - 0.0004 20.6 0.0 0.00091 19.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1830 PF08865.6 EEB07628.1 - 0.025 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) DNA_pol_B_palm PF14792.1 EEB07628.1 - 0.099 12.7 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase beta palm EAV_GS PF01309.13 EEB07628.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Acetyltransf_1 PF00583.19 EEB07629.1 - 1.6e-13 50.4 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB07629.1 - 1.4e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB07629.1 - 5.2e-06 26.5 0.0 6.4e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EEB07629.1 - 1.8e-05 24.3 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEB07629.1 - 0.0011 19.1 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEB07629.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEB07629.1 - 0.0049 16.5 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEB07629.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TRP PF06011.7 EEB07630.1 - 4.9e-48 163.7 33.1 4.9e-48 163.7 23.0 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEB07630.1 - 2e-26 92.7 0.0 3.4e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 ML-like domain zf-HYPF PF07503.7 EEB07630.1 - 0.18 11.2 0.2 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 HypF finger DUF3818 PF12825.2 EEB07631.1 - 4.8e-91 304.9 0.0 6.5e-91 304.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EEB07631.1 - 8.7e-28 96.6 0.0 1.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 PX-associated PP-binding PF00550.20 EEB07631.1 - 0.093 13.0 1.1 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Phosphopantetheine attachment site ApbA PF02558.11 EEB07632.1 - 6.9e-21 74.2 0.0 1.8e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEB07632.1 - 7.5e-19 67.9 0.0 1.4e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GATA PF00320.22 EEB07633.1 - 2.6e-16 58.6 2.3 5.6e-16 57.6 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EEB07633.1 - 7.6e-12 44.5 0.9 1.4e-11 43.6 0.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MIP-T3 PF10243.4 EEB07633.1 - 6.9 5.0 16.0 11 4.3 11.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DASH_Hsk3 PF08227.6 EEB07634.1 - 3.7e-15 55.8 2.3 4.7e-15 55.4 1.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like GvpK PF05121.7 EEB07634.1 - 0.013 15.2 1.0 0.04 13.7 0.6 1.7 1 1 1 2 2 2 0 Gas vesicle protein K Tropomyosin_1 PF12718.2 EEB07634.1 - 0.064 13.0 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Tropomyosin like FlxA PF14282.1 EEB07634.1 - 0.069 13.1 0.1 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 FlxA-like protein Wbp11 PF09429.5 EEB07634.1 - 0.1 12.6 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 DUF4332 PF14229.1 EEB07634.1 - 0.2 11.5 3.8 0.86 9.5 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4332) Sel1 PF08238.7 EEB07635.1 - 1.8e-29 101.4 11.2 8.3e-07 29.4 0.0 6.4 6 0 0 6 6 6 6 Sel1 repeat TPP_enzyme_N PF02776.13 EEB07636.1 - 1.4e-31 109.2 0.0 2.2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEB07636.1 - 9e-25 87.0 0.0 2.2e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEB07636.1 - 1.9e-17 63.2 0.0 7.4e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEB07636.1 - 0.00065 18.7 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase VWA_2 PF13519.1 EEB07636.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain MFS_1 PF07690.11 EEB07637.1 - 2.4e-19 69.2 47.9 3.7e-18 65.3 33.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB07637.1 - 4e-12 45.1 14.7 4e-12 45.1 10.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EEB07638.1 - 5.6e-55 186.3 0.0 5.2e-54 183.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07638.1 - 3.2e-26 91.9 0.0 3e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EEB07638.1 - 0.0003 21.2 0.3 0.00069 20.0 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB07638.1 - 0.0017 17.4 0.0 0.0045 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB07638.1 - 0.15 11.7 0.0 0.61 9.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Microtub_assoc PF07989.6 EEB07639.1 - 2.3e-22 78.5 7.3 2.3e-22 78.5 5.1 10.1 6 4 5 11 11 11 1 Microtubule associated Mto2_bdg PF12808.2 EEB07639.1 - 2.4e-21 75.5 7.2 2.4e-21 75.5 5.0 8.9 11 2 1 12 12 12 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EEB07639.1 - 8.1 5.5 41.2 0.41 9.7 6.8 5.2 1 1 3 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EEB07640.1 - 1.8e-45 154.5 0.0 1.6e-22 80.2 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEB07640.1 - 6e-14 52.6 3.9 0.0033 17.4 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EEB07640.1 - 3.7e-11 42.6 0.1 0.0047 16.1 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEB07640.1 - 2.2e-10 41.1 0.8 0.0031 17.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEB07640.1 - 2.7e-09 36.4 0.0 0.0029 17.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EEB07640.1 - 1.4e-08 34.9 0.3 0.0027 17.8 0.0 4.5 5 1 0 5 5 3 2 AAA domain AAA_17 PF13207.1 EEB07640.1 - 3.3e-08 34.3 0.1 0.017 15.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEB07640.1 - 1.6e-07 30.6 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEB07640.1 - 6.7e-07 29.2 0.0 0.066 13.1 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEB07640.1 - 1.5e-06 28.7 0.0 0.02 15.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EEB07640.1 - 2.4e-06 27.3 0.2 0.09 12.4 0.0 3.3 2 1 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEB07640.1 - 5.4e-06 26.3 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEB07640.1 - 5.7e-06 25.6 3.1 0.15 11.0 0.1 4.1 4 1 1 5 5 5 2 AAA ATPase domain Dynamin_N PF00350.18 EEB07640.1 - 6e-06 26.1 0.0 0.0073 16.1 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EEB07640.1 - 6.5e-06 25.7 0.1 0.17 11.2 0.0 3.3 4 0 0 4 4 3 2 AAA-like domain AAA_28 PF13521.1 EEB07640.1 - 6.6e-06 26.1 0.0 0.13 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EEB07640.1 - 3.5e-05 24.0 0.0 0.35 11.0 0.0 3.9 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB07640.1 - 3.9e-05 23.7 2.0 0.12 12.3 0.1 4.1 4 2 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.17 EEB07640.1 - 5e-05 23.4 0.0 0.39 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EEB07640.1 - 5.4e-05 22.1 0.1 0.19 10.5 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 EEB07640.1 - 8.5e-05 22.3 1.5 0.11 12.1 0.0 3.3 4 0 0 4 4 2 2 Archaeal ATPase SbcCD_C PF13558.1 EEB07640.1 - 0.0001 22.1 0.0 0.15 11.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEB07640.1 - 0.00015 22.1 0.0 0.5 10.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEB07640.1 - 0.00015 21.6 0.0 0.66 9.8 0.0 3.6 4 1 0 4 4 2 1 AAA domain DUF87 PF01935.12 EEB07640.1 - 0.00016 21.5 1.2 0.055 13.2 0.0 3.2 4 0 0 4 4 2 1 Domain of unknown function DUF87 MutS_V PF00488.16 EEB07640.1 - 0.00021 20.7 0.0 0.78 9.0 0.0 2.6 2 0 0 2 2 2 2 MutS domain V NACHT PF05729.7 EEB07640.1 - 0.00059 19.5 0.0 0.97 9.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF815 PF05673.8 EEB07640.1 - 0.0026 16.7 0.1 1.2 8.0 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) cobW PF02492.14 EEB07640.1 - 0.0028 17.1 0.0 0.79 9.1 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EEB07640.1 - 0.0034 16.9 0.1 4.1 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EEB07640.1 - 0.0036 16.7 0.0 4.2 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EEB07640.1 - 0.0048 16.3 0.0 0.9 9.0 0.0 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EEB07640.1 - 0.0088 15.1 0.0 2.6 7.0 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Septin PF00735.13 EEB07640.1 - 0.0089 15.0 0.1 4.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Septin GTP_EFTU PF00009.22 EEB07640.1 - 0.02 14.3 0.2 7.9 5.8 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 EEB07640.1 - 0.026 13.6 0.1 0.61 9.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EEB07640.1 - 0.027 14.1 0.4 8.9 5.9 0.0 3.0 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EEB07640.1 - 0.031 13.1 0.0 1.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EEB07640.1 - 0.037 13.5 0.0 9.2 5.6 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UME PF08064.8 EEB07640.1 - 0.04 13.8 0.4 12 5.8 0.1 3.5 3 1 1 4 4 2 0 UME (NUC010) domain Rad17 PF03215.10 EEB07640.1 - 0.051 12.2 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 EEB07640.1 - 0.057 12.9 0.1 8.4 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EEB07640.1 - 0.076 12.4 0.1 5.1 6.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT PF02985.17 EEB07640.1 - 0.11 12.5 0.0 84 3.6 0.2 4.2 3 0 0 3 3 3 0 HEAT repeat IstB_IS21 PF01695.12 EEB07640.1 - 0.12 11.7 0.0 6.4 6.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_13 PF13166.1 EEB07640.1 - 0.16 10.4 5.9 2.8 6.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain AMP-binding PF00501.23 EEB07642.1 - 2e-91 306.4 0.3 2.4e-91 306.1 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEB07642.1 - 7.1e-20 71.7 0.8 1.5e-19 70.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cytochrom_C PF00034.16 EEB07643.1 - 2.5e-11 44.2 0.1 4.1e-11 43.5 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EEB07643.1 - 4.2e-08 33.2 2.5 2.6e-07 30.6 1.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EEB07643.1 - 0.009 15.4 0.5 0.023 14.1 0.1 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EEB07643.1 - 0.031 14.5 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Haem_bd PF14376.1 EEB07643.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Haem-binding domain Yae1_N PF09811.4 EEB07644.1 - 1.4e-09 37.2 3.9 2.3e-09 36.6 2.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Nucleopor_Nup85 PF07575.8 EEB07644.1 - 0.057 11.6 0.0 0.066 11.4 0.0 1.0 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF3782 PF12644.2 EEB07644.1 - 0.11 12.2 0.9 0.6 9.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) zf-C3HC4_3 PF13920.1 EEB07645.1 - 2.6e-08 33.3 10.0 2.6e-08 33.3 6.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 EEB07646.2 - 6e-29 99.5 1.3 9.8e-29 98.8 0.2 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EEB07646.2 - 6.3e-09 35.4 1.3 1.8e-08 34.0 0.9 1.7 2 0 0 2 2 2 1 DEK C terminal domain Ribosomal_60s PF00428.14 EEB07646.2 - 0.17 12.3 22.2 0.59 10.5 5.8 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein MutS_V PF00488.16 EEB07647.1 - 2.1e-89 298.9 0.2 3.1e-89 298.4 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEB07647.1 - 1.2e-46 159.1 0.0 9.2e-46 156.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EEB07647.1 - 6.7e-34 116.3 0.3 6.7e-34 116.3 0.2 2.2 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.12 EEB07647.1 - 8.4e-17 61.5 0.0 2.4e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEB07647.1 - 1.1e-14 54.3 0.9 2.7e-14 53.0 0.6 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EEB07647.1 - 0.0012 19.2 0.0 0.1 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEB07647.1 - 0.0095 15.8 0.2 0.05 13.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEB07647.1 - 0.035 13.6 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEB07647.1 - 0.098 12.0 0.0 0.38 10.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ribosomal_S28e PF01200.13 EEB07648.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TRAPPC10 PF12584.3 EEB07649.2 - 1.1e-08 34.6 0.0 2.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Apc3 PF12895.2 EEB07649.2 - 0.049 13.7 0.2 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EEB07649.2 - 0.1 12.2 0.3 17 5.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EEB07650.1 - 2.3e-39 135.1 14.7 8.6e-33 113.5 6.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EEB07650.1 - 0.029 13.0 0.0 0.029 13.0 0.0 1.8 3 0 0 3 3 3 0 PUCC protein OATP PF03137.15 EEB07650.1 - 5.6 4.8 11.0 3.4 5.5 1.8 2.9 1 1 3 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family R3H PF01424.17 EEB07651.1 - 1.3e-10 40.7 0.1 2.6e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EEB07651.1 - 2.2e-09 37.0 203.9 9.8e-05 22.2 9.4 14.0 12 2 1 13 13 13 8 NF-X1 type zinc finger Sec10 PF07393.6 EEB07652.1 - 1.4e-83 281.3 10.3 4.3e-83 279.7 5.6 2.3 1 1 1 2 2 2 1 Exocyst complex component Sec10 F-box-like PF12937.2 EEB07652.1 - 1.2e-05 24.9 0.2 3.2e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEB07652.1 - 0.0007 19.1 0.1 0.0022 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain DUF4436 PF14494.1 EEB07652.1 - 0.086 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) WD40 PF00400.27 EEB07653.1 - 2.4e-92 299.8 16.6 6.4e-14 51.2 0.3 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EEB07653.1 - 5.2e-11 42.3 0.1 9.5e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EEB07653.1 - 4.9e-09 36.1 0.0 8e-05 22.4 0.0 3.8 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EEB07653.1 - 4.6e-08 31.6 11.0 0.0088 14.2 0.0 4.3 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 EEB07653.1 - 0.00045 19.7 0.1 0.00045 19.7 0.1 2.3 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EEB07653.1 - 0.0029 15.9 0.0 0.0071 14.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EEB07653.1 - 0.0046 15.7 0.0 0.98 8.0 0.0 2.7 3 0 0 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EEB07653.1 - 0.037 13.7 0.9 1.8 8.3 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EEB07653.1 - 0.094 11.7 3.8 1 8.3 0.0 3.1 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ribosomal_L31e PF01198.14 EEB07654.2 - 6.3e-37 125.1 2.0 9.4e-37 124.5 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e DUF3662 PF12401.3 EEB07654.2 - 0.11 12.6 0.2 0.46 10.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2662) Acyl-CoA_ox_N PF14749.1 EEB07654.2 - 0.14 12.4 0.3 0.18 12.1 0.2 1.4 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Methyltransf_31 PF13847.1 EEB07655.2 - 5.1e-14 52.1 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEB07655.2 - 1.7e-11 43.7 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EEB07655.2 - 1.1e-10 41.7 0.1 4.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB07655.2 - 4.1e-10 39.7 0.0 9.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EEB07655.2 - 3.4e-09 36.1 0.0 4.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EEB07655.2 - 1.6e-08 35.1 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07655.2 - 5.3e-08 32.7 0.0 8.5e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEB07655.2 - 1e-07 31.0 0.1 1.5e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EEB07655.2 - 6.4e-07 28.7 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EEB07655.2 - 1e-06 29.0 0.2 1.4e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEB07655.2 - 1.6e-06 27.6 0.2 3.4e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EEB07655.2 - 1.2e-05 25.6 0.1 4.1e-05 23.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 EEB07655.2 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EEB07655.2 - 0.0032 16.9 0.1 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 EEB07655.2 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.1 EEB07655.2 - 0.011 15.3 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEB07655.2 - 0.019 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EEB07655.2 - 0.021 15.6 0.0 0.056 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEB07655.2 - 0.022 13.8 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EEB07655.2 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EEB07655.2 - 0.066 12.3 0.2 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EEB07655.2 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Nucleoporin_C PF03177.9 EEB07656.1 - 1.2e-101 341.0 5.9 1.6e-101 340.6 4.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEB07656.1 - 1.1e-77 261.5 0.6 1.7e-77 261.0 0.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF2016 PF09436.5 EEB07656.1 - 0.14 11.7 0.3 22 4.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2016) G-patch PF01585.18 EEB07657.2 - 7.6e-11 41.6 0.3 1.6e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEB07657.2 - 0.00017 21.3 0.1 0.00017 21.3 0.1 4.1 2 1 0 3 3 3 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 EEB07657.2 - 0.014 13.9 42.2 0.019 13.4 29.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 EEB07657.2 - 0.036 13.5 30.6 0.049 13.0 21.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 EEB07657.2 - 0.036 12.3 35.0 0.043 12.1 24.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 EEB07657.2 - 0.7 8.1 39.6 0.97 7.7 27.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_viral_N PF00242.12 EEB07657.2 - 2.1 7.3 26.4 2.9 6.8 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Asp-B-Hydro_N PF05279.6 EEB07657.2 - 2.2 8.0 23.5 3 7.6 16.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CRT10 PF08728.5 EEB07657.2 - 5.2 4.9 16.0 6.2 4.6 11.1 1.1 1 0 0 1 1 1 0 CRT10 PLRV_ORF5 PF01690.12 EEB07657.2 - 7.1 5.6 24.5 9 5.3 17.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NLE PF08154.7 EEB07658.1 - 1.4e-26 92.2 0.1 2.5e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.27 EEB07658.1 - 3.9e-24 83.6 21.1 1.4e-08 34.3 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EEB07658.1 - 0.00033 18.9 6.3 0.0079 14.3 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Pkinase PF00069.20 EEB07659.1 - 2.1e-70 236.8 0.0 3.1e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07659.1 - 7.7e-44 149.7 0.0 1.1e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07659.1 - 4.3e-08 32.4 0.0 1.5e-07 30.6 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EEB07659.1 - 0.0056 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinetocho_Slk19 PF12709.2 EEB07660.1 - 6.9e-12 45.2 30.8 2.2e-10 40.4 3.5 4.9 4 1 1 5 5 5 3 Central kinetochore-associated TACC PF05010.9 EEB07660.1 - 1.2e-11 44.7 28.4 3.6e-11 43.2 19.6 1.9 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) ATG16 PF08614.6 EEB07660.1 - 0.025 14.4 0.3 0.025 14.4 0.2 4.0 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF4286 PF14114.1 EEB07660.1 - 2.4 8.4 9.1 0.46 10.7 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) TPR_MLP1_2 PF07926.7 EEB07660.1 - 8.6 6.1 34.8 1.5 8.6 5.3 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LNS2 PF08235.8 EEB07662.1 - 1.1e-71 239.5 0.0 1.8e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EEB07662.1 - 7.7e-43 144.6 0.0 1.7e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 EEB07662.1 - 1.5e-06 28.0 4.2 4.4e-06 26.5 2.9 1.7 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 EEB07662.1 - 0.00016 21.1 0.0 0.0017 17.7 0.0 2.5 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) NOSIC PF08060.8 EEB07662.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 NOSIC (NUC001) domain PCI PF01399.22 EEB07663.1 - 8e-05 22.9 0.0 0.00013 22.2 0.0 1.4 1 1 0 1 1 1 1 PCI domain BRCA2 PF00634.13 EEB07663.1 - 0.019 14.2 0.1 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 BRCA2 repeat Sigma70_r1_1 PF03979.9 EEB07663.1 - 0.12 12.2 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Rieske PF00355.21 EEB07663.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain NPR2 PF06218.6 EEB07664.1 - 2.9e-139 464.4 5.8 3.6e-137 457.5 4.0 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EEB07664.1 - 2.8e-06 26.1 2.0 0.082 11.4 0.4 2.9 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 DRIM PF07539.7 EEB07664.1 - 0.07 12.5 0.1 0.88 8.9 0.0 2.4 3 0 0 3 3 3 0 Down-regulated in metastasis Amidohydro_1 PF01979.15 EEB07665.1 - 1e-58 199.6 1.3 1.4e-58 199.1 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EEB07665.1 - 3.9e-51 172.2 1.5 7.3e-51 171.3 1.0 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EEB07665.1 - 2.3e-40 136.4 0.0 4.8e-40 135.4 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EEB07665.1 - 9.2e-36 121.8 0.0 1.9e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EEB07665.1 - 2.2e-07 30.5 2.7 2.5e-07 30.4 0.8 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EEB07665.1 - 0.00064 19.0 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.9 EEB07665.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase TMEM52 PF14979.1 EEB07666.2 - 0.0081 16.0 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Transmembrane 52 DUF3487 PF11990.3 EEB07666.2 - 0.23 10.8 1.3 0.68 9.3 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) WD40 PF00400.27 EEB07667.1 - 1.3e-14 53.3 5.4 6.4e-09 35.3 0.5 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EEB07667.1 - 8.2e-07 28.9 0.3 0.0017 18.1 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEB07667.1 - 1e-06 27.3 0.1 0.02 13.1 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain AcetylCoA_hydro PF02550.10 EEB07668.1 - 4.5e-47 160.3 0.0 7.1e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EEB07668.1 - 2e-41 141.2 0.0 3e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EEB07668.1 - 0.043 12.9 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Coenzyme A transferase CitF PF04223.7 EEB07668.1 - 0.12 11.0 0.0 0.29 9.7 0.0 1.6 2 0 0 2 2 2 0 Citrate lyase, alpha subunit (CitF) Pyridox_oxidase PF01243.15 EEB07669.1 - 9.1e-13 48.0 0.0 2.1e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EEB07669.1 - 0.0015 18.3 0.0 0.0051 16.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EEB07669.1 - 0.038 14.3 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Rad1 PF02144.11 EEB07670.1 - 2.6e-63 213.3 1.1 3e-63 213.1 0.8 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CTNNBL PF08216.6 EEB07671.1 - 9.5e-31 105.5 0.8 9.5e-31 105.5 0.6 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.4 EEB07671.1 - 0.036 13.8 2.3 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Bromodomain PF00439.20 EEB07672.1 - 6.3e-26 90.1 3.0 1.1e-25 89.3 1.1 2.2 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 EEB07672.1 - 8.5e-09 35.4 0.6 2e-08 34.2 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB07672.1 - 3.5e-08 33.3 0.2 7.4e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family OTU PF02338.14 EEB07673.1 - 1.5e-21 77.1 0.0 1.5e-21 77.1 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEB07673.1 - 4.4e-08 32.7 0.0 4.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase C65 Otubain Lyase_catalyt PF09093.6 EEB07673.1 - 0.013 14.4 0.9 0.013 14.4 0.6 2.1 2 0 0 2 2 2 0 Lyase, catalytic DUF4407 PF14362.1 EEB07673.1 - 2.9 6.7 12.4 5.2 5.9 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G-patch PF01585.18 EEB07674.1 - 0.008 15.9 0.3 0.019 14.7 0.2 1.7 1 0 0 1 1 1 1 G-patch domain Peptidase_C37 PF05416.7 EEB07674.1 - 0.085 11.1 5.8 0.089 11.0 4.0 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Zip PF02535.17 EEB07674.1 - 0.32 9.9 12.7 0.36 9.8 8.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 EEB07674.1 - 0.57 10.0 11.6 0.64 9.8 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 EEB07674.1 - 0.75 9.4 28.3 0.9 9.1 19.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 EEB07674.1 - 1.2 8.5 22.2 1.6 8.2 15.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 EEB07674.1 - 1.4 8.6 11.4 1.5 8.5 7.9 1.2 1 0 0 1 1 1 0 DDHD domain Hex_IIIa PF02455.11 EEB07674.1 - 3.5 6.2 9.7 4 6.0 6.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PIG-U PF06728.8 EEB07675.1 - 2.8e-88 296.3 37.2 3.4e-88 296.0 25.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ribosomal_S11 PF00411.14 EEB07676.1 - 8.3e-12 45.2 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Clr2 PF10383.4 EEB07677.2 - 2.5e-16 59.9 0.0 4.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 MFS_1 PF07690.11 EEB07678.1 - 1.1e-28 99.9 35.4 1.6e-28 99.4 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-LITAF-like PF10601.4 EEB07678.1 - 6.4 6.7 6.7 4.5 7.1 0.4 3.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain MFS_1 PF07690.11 EEB07679.1 - 5.4e-28 97.7 27.5 5.4e-28 97.7 19.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEB07679.1 - 0.00048 18.6 5.6 0.00048 18.6 3.9 3.0 2 1 0 3 3 3 1 MFS/sugar transport protein 2TM PF13239.1 EEB07679.1 - 9.1 6.4 12.3 0.09 12.8 0.6 3.1 3 0 0 3 3 3 0 2TM domain ATP-synt_C PF00137.16 EEB07680.2 - 1.5e-13 50.4 25.2 1.9e-12 46.8 9.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SKG6 PF08693.5 EEB07680.2 - 0.35 10.2 0.1 0.35 10.2 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2232 PF09991.4 EEB07680.2 - 7.1 5.5 11.7 8.5 5.2 8.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PMM PF03332.8 EEB07681.1 - 2.9e-114 380.1 0.3 3.3e-114 379.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EEB07681.1 - 0.00033 20.3 0.0 0.0022 17.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EEB07681.1 - 0.021 13.9 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein RHH_1 PF01402.16 EEB07681.1 - 0.029 14.2 0.0 4.4 7.3 0.0 3.1 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Hydrolase PF00702.21 EEB07681.1 - 0.031 14.6 0.0 0.045 14.1 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB07681.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_8 PF13450.1 EEB07682.1 - 7.1e-14 51.5 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEB07682.1 - 0.013 15.3 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EEB07682.1 - 0.056 12.3 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ost4 PF10215.4 EEB07682.1 - 0.23 10.9 0.5 0.46 10.0 0.4 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase CBS PF00571.23 EEB07683.2 - 5.2e-25 86.9 2.5 4.6e-10 39.1 0.1 4.3 4 0 0 4 4 4 4 CBS domain TCTP PF00838.12 EEB07684.1 - 2.1e-74 249.0 1.6 2.4e-74 248.8 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PEX11 PF05648.9 EEB07685.1 - 0.013 14.7 1.9 0.013 14.7 0.4 1.6 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) LDB19 PF13002.2 EEB07686.1 - 5.8e-33 113.9 2.2 9.7e-33 113.2 1.5 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EEB07686.1 - 5.8e-07 29.4 0.1 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEB07686.1 - 0.025 14.6 0.1 0.32 11.1 0.0 2.2 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Endonuclease_5 PF04493.9 EEB07687.1 - 1.2e-53 181.6 0.0 1.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 EEB07687.1 - 0.0031 16.6 0.1 0.0056 15.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF99 UvrC_HhH_N PF08459.6 EEB07687.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Aminotran_5 PF00266.14 EEB07688.1 - 5.3e-38 130.7 0.0 6.2e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V CTP_transf_2 PF01467.21 EEB07690.1 - 4.2e-07 30.1 0.1 1.6e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 Cytidylyltransferase PIG-S PF10510.4 EEB07691.2 - 5.9e-82 275.9 8.6 3.2e-80 270.2 6.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TMEMspv1-c74-12 PF11044.3 EEB07691.2 - 0.58 9.7 3.3 1.4 8.5 2.3 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cyt-b5 PF00173.23 EEB07692.1 - 7.9e-24 83.2 0.0 1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cep57_MT_bd PF06657.8 EEB07693.1 - 1.5e-25 88.9 1.0 1.5e-25 88.9 0.7 4.0 2 1 2 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EEB07693.1 - 3.9e-17 61.9 13.6 3.9e-17 61.9 9.5 2.9 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 FlaC_arch PF05377.6 EEB07693.1 - 7.8 6.4 10.0 1.4 8.9 1.5 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PK PF00224.16 EEB07694.1 - 3.5e-168 558.6 4.4 4.5e-168 558.2 3.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EEB07694.1 - 3.9e-28 97.3 1.3 1.1e-27 95.8 0.2 2.3 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EEB07694.1 - 5.9e-05 22.0 1.1 0.00018 20.5 0.4 2.2 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EEB07694.1 - 0.0078 15.1 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DnaJ-X PF14308.1 EEB07695.1 - 9.8e-57 191.5 1.3 1.1e-56 191.3 0.1 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EEB07695.1 - 1.6e-27 95.0 1.8 1.6e-27 95.0 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain TetR_C_6 PF13977.1 EEB07695.1 - 0.13 12.3 3.3 7.8 6.5 1.1 2.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor FHIPEP PF00771.15 EEB07695.1 - 0.21 9.8 0.7 0.34 9.1 0.5 1.2 1 0 0 1 1 1 0 FHIPEP family DUF935 PF06074.7 EEB07696.1 - 0.18 10.4 0.6 0.25 10.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Glyco_hydro_15 PF00723.16 EEB07697.1 - 1.1e-64 218.6 0.0 1.5e-63 214.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 ORC2 PF04084.9 EEB07698.1 - 1.2e-98 329.9 0.2 1.6e-98 329.6 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 EEB07698.1 - 0.032 13.8 4.5 0.066 12.9 3.1 1.6 1 0 0 1 1 1 0 AT hook motif Borrelia_REV PF03978.8 EEB07698.1 - 0.1 12.3 0.6 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Cupredoxin_1 PF13473.1 EEB07699.2 - 0.043 13.7 0.0 0.081 12.8 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain Ribosomal_L27e PF01777.13 EEB07700.1 - 8e-39 131.6 2.2 1.1e-38 131.2 1.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEB07700.1 - 1.6e-05 24.4 0.1 4.6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 KOW motif SLA_LP_auto_ag PF05889.8 EEB07700.1 - 0.12 10.8 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ribosomal_S2 PF00318.15 EEB07701.2 - 1.2e-43 148.7 0.0 2.5e-21 75.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 PIG-H PF10181.4 EEB07702.1 - 1.7e-21 75.5 0.1 3e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component BC10 PF06726.7 EEB07702.1 - 0.045 13.7 2.2 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Clat_adaptor_s PF01217.15 EEB07703.1 - 4.2e-51 172.4 2.3 4.6e-51 172.2 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Exo5 PF09810.4 EEB07705.1 - 1.9e-73 247.5 1.7 2e-73 247.4 0.1 1.7 1 1 1 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EEB07705.1 - 7.3e-06 25.5 1.2 3.1e-05 23.4 0.8 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily INCENP_ARK-bind PF03941.10 EEB07706.1 - 3.6e-21 74.7 5.7 5.6e-21 74.1 1.5 2.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Pkinase PF00069.20 EEB07707.1 - 9e-07 28.2 0.4 5.7e-06 25.6 0.0 2.2 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07707.1 - 0.0025 16.9 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S24 PF00717.18 EEB07708.1 - 4.6e-08 32.5 0.1 1.3e-07 31.1 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEB07708.1 - 2.3e-07 30.4 0.0 0.00039 19.9 0.0 2.6 1 1 2 3 3 3 2 Signal peptidase, peptidase S26 Ank_4 PF13637.1 EEB07709.1 - 1.5e-15 57.1 3.7 3e-07 30.7 0.2 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB07709.1 - 4.7e-15 55.7 1.6 1.1e-07 32.1 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEB07709.1 - 4.5e-12 44.9 4.7 0.00015 21.6 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EEB07709.1 - 5.9e-12 44.7 5.5 0.00018 21.1 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EEB07709.1 - 1.8e-10 40.7 2.8 3.7e-05 23.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NIT PF08376.5 EEB07709.1 - 0.036 13.5 7.2 0.1 12.0 5.0 1.7 1 0 0 1 1 1 0 Nitrate and nitrite sensing DUF745 PF05335.8 EEB07709.1 - 0.19 11.2 3.0 0.47 9.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 EEB07709.1 - 9.4 5.7 16.8 0.27 10.8 4.8 2.2 2 0 0 2 2 2 0 IncA protein Vps52 PF04129.7 EEB07710.1 - 1.1e-127 426.6 4.2 1.4e-127 426.3 2.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family eIF-5a PF01287.15 EEB07711.1 - 1.1e-26 92.5 0.2 1.5e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEB07711.1 - 1.9e-05 24.1 1.5 3.7e-05 23.2 1.0 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEB07711.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EEB07712.1 - 3.9e-08 32.6 0.8 6.6e-08 31.9 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Spc24 PF08286.6 EEB07713.1 - 1.2e-24 86.2 1.7 1.2e-24 86.2 1.1 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 EEB07713.1 - 0.068 11.0 5.9 0.072 10.9 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EEB07713.1 - 0.3 10.9 15.3 2 8.2 10.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 EEB07713.1 - 0.33 10.6 8.3 0.83 9.3 0.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Sec2p PF06428.6 EEB07713.1 - 0.55 10.1 11.8 0.099 12.4 3.2 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Reo_sigmaC PF04582.7 EEB07713.1 - 0.63 9.1 3.6 0.74 8.9 2.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tup_N PF08581.5 EEB07713.1 - 0.87 9.8 6.4 0.14 12.3 0.8 2.1 1 1 0 2 2 2 0 Tup N-terminal PEP-utilisers_N PF05524.8 EEB07713.1 - 0.99 9.2 4.6 0.37 10.5 0.7 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal TBCA PF02970.11 EEB07713.1 - 1.1 9.3 8.3 1.6 8.8 0.9 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Halogen_Hydrol PF10112.4 EEB07713.1 - 1.4 8.2 7.0 1 8.7 0.8 2.2 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein IncA PF04156.9 EEB07713.1 - 8.5 5.9 14.6 13 5.3 10.1 1.2 1 0 0 1 1 1 0 IncA protein B-block_TFIIIC PF04182.7 EEB07714.2 - 8.4e-17 60.7 0.1 3.4e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EEB07714.2 - 0.041 13.2 1.5 6.8 6.1 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Methyltransf_12 PF08242.7 EEB07715.1 - 2.2e-08 34.4 0.0 3.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07715.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB07715.1 - 4.2e-07 30.2 0.0 9.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB07715.1 - 2.7e-06 27.7 0.0 5.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB07715.1 - 1.5e-05 24.6 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07715.1 - 0.00033 21.2 0.0 0.00057 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DNA_pol_B PF00136.16 EEB07716.1 - 4.4e-145 484.0 1.0 6.4e-145 483.4 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEB07716.1 - 1.1e-90 303.8 1.4 1.4e-90 303.4 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEB07716.1 - 6.9e-25 86.8 4.0 1.6e-24 85.7 2.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EEB07716.1 - 0.00048 19.9 0.0 0.0021 17.8 0.0 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EEB07716.1 - 0.0018 16.9 1.7 0.0034 16.1 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF2660 PF10859.3 EEB07716.1 - 0.068 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF1476 PF07345.6 EEB07716.1 - 0.088 13.0 0.7 21 5.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) RasGEF PF00617.14 EEB07717.1 - 2.5e-48 164.3 0.0 7e-48 162.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEB07717.1 - 1.3e-17 63.7 0.1 3.5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.21 EEB07717.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 WW domain RrnaAD PF00398.15 EEB07718.1 - 3.3e-60 203.3 0.0 4.3e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EEB07718.1 - 4.4e-10 39.6 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07718.1 - 6.2e-06 26.7 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB07718.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EEB07718.1 - 0.00015 21.4 0.0 0.00039 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07718.1 - 0.00017 21.3 0.0 0.00053 19.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EEB07718.1 - 0.00034 19.9 0.0 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 EEB07718.1 - 0.00035 20.9 0.0 0.00068 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEB07718.1 - 0.00049 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EEB07718.1 - 0.0028 16.5 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Met_10 PF02475.11 EEB07718.1 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EEB07718.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EEB07718.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EEB07718.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EEB07718.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) UvrD-helicase PF00580.16 EEB07719.1 - 7.5e-15 55.0 3.3 1.4e-10 41.0 2.3 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EEB07719.1 - 4.2e-13 49.5 0.0 1.3e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EEB07719.1 - 1.3e-09 37.9 0.1 0.026 14.0 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EEB07719.1 - 4.1e-08 33.2 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EEB07719.1 - 0.00025 20.6 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEB07719.1 - 0.0046 16.6 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EEB07719.1 - 0.0075 15.5 0.1 0.9 8.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EEB07719.1 - 0.029 14.5 0.2 1.2 9.2 0.1 2.7 1 1 0 1 1 1 0 AAA domain Lung_7-TM_R PF06814.8 EEB07720.1 - 2.6e-38 131.6 18.5 3.1e-38 131.3 12.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Arf PF00025.16 EEB07721.1 - 1.6e-80 268.4 0.1 1.9e-80 268.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEB07721.1 - 2e-14 53.2 0.0 2.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEB07721.1 - 8.9e-14 51.1 0.0 9.6e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEB07721.1 - 3.1e-11 42.6 1.1 6.1e-08 31.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEB07721.1 - 4.3e-10 39.1 0.0 5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEB07721.1 - 1.2e-08 35.4 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEB07721.1 - 4.9e-06 26.4 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EEB07721.1 - 0.0057 15.7 0.1 0.01 14.8 0.0 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EEB07721.1 - 0.026 13.9 0.1 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EEB07721.1 - 0.088 12.6 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEB07721.1 - 0.12 11.8 0.0 2 7.9 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_2 PF07724.9 EEB07722.2 - 2.4e-50 170.8 0.2 4.3e-48 163.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EEB07722.2 - 1.2e-26 92.4 0.3 5.3e-26 90.3 0.2 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EEB07722.2 - 8.4e-19 68.0 0.0 7.2e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB07722.2 - 1.3e-16 61.1 8.8 5.1e-05 23.3 0.0 5.4 3 2 1 5 5 5 3 AAA ATPase domain AAA_5 PF07728.9 EEB07722.2 - 2.2e-13 50.1 0.0 2.8e-09 36.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEB07722.2 - 4.7e-09 36.4 1.9 0.0006 19.9 0.0 4.1 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEB07722.2 - 1.1e-07 31.4 0.2 4.5e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EEB07722.2 - 6.5e-07 29.1 0.2 0.05 13.2 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 EEB07722.2 - 7.1e-07 30.0 3.7 0.04 14.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EEB07722.2 - 1.1e-06 28.2 0.0 0.051 12.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EEB07722.2 - 1.5e-06 28.1 0.0 0.11 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEB07722.2 - 4.6e-06 26.5 6.8 0.0074 16.0 0.1 4.4 3 2 0 3 3 3 2 Archaeal ATPase AAA_18 PF13238.1 EEB07722.2 - 2.1e-05 24.8 0.6 0.44 10.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EEB07722.2 - 4e-05 23.9 0.6 0.19 12.0 0.0 3.6 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EEB07722.2 - 5.4e-05 23.3 0.1 0.92 9.7 0.1 3.5 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EEB07722.2 - 9.8e-05 21.6 0.8 0.23 10.5 0.0 3.7 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EEB07722.2 - 0.00012 21.9 1.3 0.19 11.5 0.0 3.8 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit MobB PF03205.9 EEB07722.2 - 0.00014 21.5 0.0 0.73 9.5 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEB07722.2 - 0.00017 21.1 0.5 0.14 11.5 0.0 4.0 2 2 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EEB07722.2 - 0.0002 20.5 0.0 0.63 9.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEB07722.2 - 0.00046 19.6 0.0 0.55 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEB07722.2 - 0.00051 20.0 2.5 1.7 8.5 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EEB07722.2 - 0.00056 19.3 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RuvB_N PF05496.7 EEB07722.2 - 0.002 17.2 1.5 0.27 10.2 0.0 3.2 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TrwB_AAD_bind PF10412.4 EEB07722.2 - 0.0022 16.6 0.0 0.46 9.0 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.1 EEB07722.2 - 0.0023 17.9 0.2 1.8 8.4 0.0 3.8 3 1 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EEB07722.2 - 0.0026 17.7 0.0 3 7.8 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.17 EEB07722.2 - 0.007 15.8 0.0 2.2 7.6 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.1 EEB07722.2 - 0.0081 15.8 0.0 0.088 12.4 0.0 2.6 3 1 0 3 3 2 1 DNA polymerase III, delta subunit AAA_23 PF13476.1 EEB07722.2 - 0.0082 16.4 18.0 0.77 10.0 0.0 3.7 2 2 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EEB07722.2 - 0.01 15.3 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EEB07722.2 - 0.02 14.4 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EEB07722.2 - 0.021 14.6 6.0 1.9 8.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EEB07722.2 - 0.059 12.8 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEB07722.2 - 0.08 13.4 0.4 22 5.5 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 EEB07722.2 - 0.084 12.5 0.0 7.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 EEB07722.2 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Effector_1 PF04518.7 EEB07722.2 - 0.13 11.1 3.7 0.27 10.2 2.6 1.4 1 0 0 1 1 1 0 Effector from type III secretion system DUF972 PF06156.8 EEB07722.2 - 0.2 12.0 7.4 0.74 10.1 5.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_33 PF13671.1 EEB07722.2 - 0.25 11.1 5.8 8.5 6.2 0.1 4.2 4 2 0 4 4 4 0 AAA domain Nup54 PF13874.1 EEB07722.2 - 0.33 10.6 12.4 0.91 9.1 8.6 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ALMT PF11744.3 EEB07722.2 - 0.53 8.8 1.8 0.91 8.1 1.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF724 PF05266.9 EEB07722.2 - 0.97 9.0 10.5 1.9 8.0 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EEB07722.2 - 1.1 6.9 7.4 1.7 6.4 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PLRV_ORF5 PF01690.12 EEB07722.2 - 1.9 7.5 4.5 2.9 6.9 3.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein OmpH PF03938.9 EEB07722.2 - 2.1 8.2 14.8 1.5 8.7 8.5 2.0 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) ERO1 PF04137.10 EEB07723.1 - 8e-112 373.7 0.4 9.8e-112 373.4 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Rad10 PF03834.9 EEB07724.2 - 4.2e-30 103.2 0.0 6.8e-30 102.5 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EEB07724.2 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EEB07724.2 - 9.2e-05 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HRDC PF00570.18 EEB07724.2 - 0.0063 16.2 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 HRDC domain HHH_3 PF12836.2 EEB07724.2 - 0.011 15.6 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 EEB07724.2 - 0.027 14.1 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif FANCI_HD1 PF14679.1 EEB07724.2 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 FANCI helical domain 1 RRM_1 PF00076.17 EEB07725.2 - 8.5e-62 204.7 0.3 4.6e-21 74.2 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07725.2 - 1.4e-44 149.9 0.2 1e-16 60.6 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07725.2 - 6.8e-24 83.4 0.2 4.1e-11 42.5 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 EEB07725.2 - 2.3 7.1 6.4 0.23 10.4 0.9 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter BOP1NT PF08145.7 EEB07726.1 - 9.8e-94 313.9 3.4 1.9e-93 312.9 2.4 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EEB07726.1 - 1.3e-28 97.7 11.8 5.4e-08 32.4 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF3312 PF11768.3 EEB07726.1 - 0.0061 14.8 0.0 0.014 13.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 EEB07726.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region LIM PF00412.17 EEB07727.2 - 2.1e-27 94.9 36.6 3.6e-12 46.1 5.7 3.2 3 0 0 3 3 3 3 LIM domain APC_crr PF05923.7 EEB07727.2 - 0.079 12.6 1.5 25 4.6 0.5 3.4 3 0 0 3 3 3 0 APC cysteine-rich region Asn_synthase PF00733.16 EEB07728.1 - 1.9e-47 161.9 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEB07728.1 - 1.9e-14 53.4 0.0 4.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEB07728.1 - 2.8e-10 40.2 0.0 6.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain HTH_20 PF12840.2 EEB07728.1 - 0.16 11.7 0.8 0.91 9.3 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain VPS9 PF02204.13 EEB07729.1 - 1.3e-30 105.4 0.2 2.9e-30 104.3 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EEB07729.1 - 1.4e-10 40.4 0.0 2.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.11 EEB07730.2 - 2.8e-21 75.6 52.8 3e-20 72.2 35.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB07730.2 - 9.3e-13 47.2 26.3 1.3e-12 46.7 18.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DEAD PF00270.24 EEB07731.1 - 9.5e-44 148.8 0.3 2.4e-43 147.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07731.1 - 3.7e-25 87.5 0.0 1.1e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEB07731.1 - 2.5e-05 23.2 0.0 4.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EEB07731.1 - 0.00036 20.5 0.0 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EEB07731.1 - 0.0017 16.8 0.3 0.021 13.2 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EEB07731.1 - 0.057 13.5 3.0 0.62 10.2 2.1 2.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEB07731.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L33 PF00471.15 EEB07732.1 - 1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 BRCT PF00533.21 EEB07733.1 - 6.8e-23 80.6 7.4 1.1e-08 35.0 0.0 6.3 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB07733.1 - 2.1e-20 72.3 1.2 1.7e-12 46.9 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain WI12 PF07107.6 EEB07733.1 - 0.016 15.0 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Wound-induced protein WI12 Hydrolase_6 PF13344.1 EEB07733.1 - 0.077 12.8 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EEB07734.1 - 3.5e-77 259.0 0.0 7.1e-77 258.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07734.1 - 3e-36 124.8 0.0 1.1e-35 122.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EEB07734.1 - 2.6e-15 55.5 0.0 5e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EEB07734.1 - 2.5e-07 29.9 0.1 5.9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEB07734.1 - 2.9e-06 26.4 0.0 9e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB07734.1 - 0.00021 21.1 0.1 0.11 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EEB07734.1 - 0.0023 17.2 0.3 0.004 16.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EEB07734.1 - 0.034 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EEB07734.1 - 0.25 10.1 0.0 0.76 8.5 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 TFIIF_alpha PF05793.7 EEB07734.1 - 2.1 6.6 5.9 3.9 5.7 4.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lectin_leg-like PF03388.8 EEB07735.1 - 1.2e-28 99.8 0.1 1.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Tropomyosin PF00261.15 EEB07735.1 - 0.0049 15.9 3.2 0.0078 15.3 2.2 1.2 1 0 0 1 1 1 1 Tropomyosin DUF2407_C PF13373.1 EEB07735.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain IncA PF04156.9 EEB07735.1 - 0.1 12.1 3.4 0.52 9.8 2.6 1.8 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 EEB07735.1 - 1 7.6 2.4 1.1 7.6 1.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 EEB07735.1 - 1.2 8.9 6.6 2.8 7.7 4.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EEB07735.1 - 1.3 8.8 6.0 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Ribosomal_L23eN PF03939.8 EEB07736.1 - 2.6e-19 68.9 6.5 2.6e-19 68.9 4.5 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EEB07736.1 - 7.8e-18 64.2 2.8 7.8e-18 64.2 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 EEB07736.1 - 0.074 12.8 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal HMGL-like PF00682.14 EEB07737.1 - 4.2e-63 213.1 0.0 6.4e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EEB07737.1 - 6.1e-25 87.5 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain TLC PF03219.9 EEB07737.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter TRAM_LAG1_CLN8 PF03798.11 EEB07738.2 - 3.4e-32 111.6 30.6 3.4e-32 111.6 21.2 2.4 2 1 1 3 3 3 1 TLC domain TRAM1 PF08390.6 EEB07738.2 - 5.5e-19 67.4 0.1 5.5e-19 67.4 0.1 2.4 2 0 0 2 2 2 1 TRAM1-like protein LSM PF01423.17 EEB07739.2 - 2.9e-21 74.7 0.0 3.3e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB07739.2 - 0.0032 17.3 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SYF2 PF08231.7 EEB07740.2 - 8e-44 149.4 23.2 8e-44 149.4 16.1 2.1 2 0 0 2 2 2 1 SYF2 splicing factor Sel1 PF08238.7 EEB07741.1 - 1.1e-10 41.7 10.5 0.00025 21.5 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 EEB07741.1 - 8.5e-05 22.1 2.0 0.00023 20.7 1.4 1.7 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EEB07741.1 - 0.00017 21.4 2.4 0.00021 21.1 0.6 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEB07741.1 - 0.0062 16.2 0.1 0.022 14.5 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB07741.1 - 0.011 15.3 0.8 0.011 15.3 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ftsk_gamma PF09397.5 EEB07741.1 - 0.099 12.3 0.1 5.8 6.7 0.0 2.8 2 0 0 2 2 2 0 Ftsk gamma domain TPR_17 PF13431.1 EEB07741.1 - 0.27 11.5 1.2 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PAH PF02671.16 EEB07742.1 - 2.8e-40 135.6 5.5 3.2e-14 52.2 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EEB07742.1 - 7e-38 128.4 2.0 2.5e-37 126.6 0.1 2.8 2 0 0 2 2 2 1 Sin3 family co-repressor HlyIII PF03006.15 EEB07743.1 - 8.1e-62 208.5 19.3 9.7e-62 208.2 13.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2583 PF10762.4 EEB07743.1 - 0.18 11.9 1.2 4.8 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF1129 PF06570.6 EEB07743.1 - 1.1 8.4 6.0 0.43 9.8 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Dynamin_M PF01031.15 EEB07744.1 - 2.1e-98 328.7 0.0 3.8e-98 327.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EEB07744.1 - 1.9e-53 180.7 0.8 5.1e-53 179.3 0.1 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EEB07744.1 - 7.6e-28 96.2 4.6 2.4e-27 94.6 3.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain SWI-SNF_Ssr4 PF08549.5 EEB07744.1 - 0.00044 18.7 1.0 0.00063 18.1 0.7 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) MMR_HSR1 PF01926.18 EEB07744.1 - 0.0032 17.4 0.5 0.019 14.8 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEB07744.1 - 0.0039 17.6 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Condensin2nSMC PF12422.3 EEB07744.1 - 0.028 14.1 1.3 0.083 12.6 0.9 1.8 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit NOB1_Zn_bind PF08772.6 EEB07744.1 - 0.066 13.0 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like AAA_28 PF13521.1 EEB07744.1 - 0.14 12.0 0.2 1 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Med7 PF05983.6 EEB07745.1 - 1.8e-45 154.6 12.4 2.3e-44 151.0 8.6 2.2 1 1 0 1 1 1 1 MED7 protein DUF3349 PF11829.3 EEB07745.1 - 0.21 12.0 1.4 0.38 11.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) DivIC PF04977.10 EEB07745.1 - 7 6.2 7.0 1.1 8.8 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Lyase_1 PF00206.15 EEB07746.1 - 1.5e-22 80.1 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EEB07746.1 - 1.2e-14 54.0 0.0 2.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus LON PF02190.11 EEB07747.1 - 1.9e-26 93.0 0.0 2.7e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EEB07747.1 - 3.7e-12 46.0 26.5 2.8e-09 36.8 6.3 3.1 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB07747.1 - 3.3e-11 42.8 21.3 7e-06 25.8 5.6 3.5 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEB07747.1 - 1.2e-10 41.0 22.3 9e-09 35.0 6.0 3.0 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 EEB07747.1 - 1.6e-09 37.2 21.7 3.2e-07 29.8 6.4 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07747.1 - 1.8e-09 37.1 21.9 3.3e-08 33.1 4.8 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEB07747.1 - 3.4e-09 36.2 20.2 8.8e-08 31.6 4.1 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB07747.1 - 0.00018 21.1 20.4 0.0061 16.2 3.6 2.7 2 0 0 2 2 2 2 RING-type zinc-finger U-box PF04564.10 EEB07747.1 - 0.00083 19.2 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 U-box domain zf-RING_4 PF14570.1 EEB07747.1 - 0.0023 17.4 5.5 0.0023 17.4 3.8 3.2 2 2 0 2 2 2 1 RING/Ubox like zinc-binding domain RRN7 PF11781.3 EEB07747.1 - 0.82 9.2 4.6 3 7.4 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Prok-RING_4 PF14447.1 EEB07747.1 - 1.9 8.1 14.1 0.55 9.8 1.6 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EEB07747.1 - 4.2 7.5 13.2 0.084 12.9 3.4 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger PX PF00787.19 EEB07748.2 - 1.3e-19 70.0 0.3 3.9e-19 68.5 0.2 1.8 1 0 0 1 1 1 1 PX domain She9_MDM33 PF05546.6 EEB07748.2 - 0.0077 15.8 1.7 0.023 14.2 0.7 2.1 2 0 0 2 2 2 1 She9 / Mdm33 family DUF2535 PF10751.4 EEB07748.2 - 0.026 14.6 0.1 0.059 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) Alk_phosphatase PF00245.15 EEB07749.1 - 6.5e-103 344.6 0.0 7.9e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EEB07749.1 - 4.9e-05 22.8 0.1 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Metallophos PF00149.23 EEB07750.1 - 7.9e-38 129.8 0.0 1.2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EEB07750.1 - 3e-30 103.6 5.9 4.9e-22 77.3 0.4 2.6 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 EEB07750.1 - 2.3e-27 94.8 0.0 5.3e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 EEB07750.1 - 3.9e-20 70.0 9.4 4.9e-07 29.1 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEB07750.1 - 2.5e-19 68.0 11.1 1.3e-08 34.0 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEB07750.1 - 1.1e-10 40.8 4.0 4.4e-05 23.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB07750.1 - 1e-09 38.7 1.2 9.7e-07 29.3 0.0 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB07750.1 - 1.1e-07 32.0 1.0 0.006 16.8 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB07750.1 - 7.6e-07 29.2 0.3 0.19 12.4 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB07750.1 - 6.6e-06 25.8 0.0 0.003 17.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB07750.1 - 8.4e-06 25.6 1.0 0.0006 19.7 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB07750.1 - 1.1e-05 24.8 5.4 0.098 12.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB07750.1 - 0.0035 17.0 0.3 0.23 11.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEB07750.1 - 0.023 14.8 5.5 0.042 13.9 1.8 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEB07750.1 - 0.024 15.1 2.3 3.9 8.1 0.3 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 EEB07750.1 - 0.077 12.8 1.5 0.6 10.0 0.0 2.7 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain P4Ha_N PF08336.6 EEB07750.1 - 0.089 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_15 PF13429.1 EEB07750.1 - 0.11 11.5 0.2 0.8 8.7 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat 3Beta_HSD PF01073.14 EEB07751.1 - 3.3e-65 219.5 0.0 3.8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEB07751.1 - 7.5e-31 107.3 0.0 9.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEB07751.1 - 4.1e-18 65.2 0.0 5.4e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEB07751.1 - 9.1e-13 48.6 0.0 1.7e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEB07751.1 - 3.1e-11 42.6 0.1 6.3e-10 38.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEB07751.1 - 1.5e-08 33.8 0.1 1e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEB07751.1 - 1.4e-07 31.6 0.0 4.4e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EEB07751.1 - 0.00019 20.5 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EEB07751.1 - 0.00028 20.6 0.0 0.005 16.5 0.0 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EEB07751.1 - 0.0034 16.6 0.1 0.0049 16.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EEB07751.1 - 0.0041 17.0 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EEB07751.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus B12-binding PF02310.14 EEB07751.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain GTP_EFTU PF00009.22 EEB07752.2 - 8.7e-39 132.9 0.9 8.1e-38 129.7 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEB07752.2 - 3.3e-15 55.9 0.4 7.4e-15 54.7 0.3 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EEB07752.2 - 3.5e-09 36.6 0.0 1.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEB07752.2 - 7.4e-06 26.4 0.0 1.9e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EEB07752.2 - 0.00015 21.2 0.1 0.00051 19.5 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EEB07752.2 - 0.00047 19.4 0.0 0.00093 18.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EEB07752.2 - 0.00095 19.0 0.9 0.13 12.1 0.0 2.9 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 EEB07752.2 - 0.0022 17.3 0.0 0.0084 15.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EEB07752.2 - 0.0031 16.7 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase PF00702.21 EEB07752.2 - 0.059 13.7 1.1 0.26 11.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EEB07753.1 - 2.9e-12 46.7 0.2 4.8e-12 46.0 0.2 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEB07753.1 - 5.1e-11 41.8 2.5 3.6e-05 23.3 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEB07753.1 - 1.7e-10 40.7 1.0 7e-08 32.4 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEB07753.1 - 2e-08 34.5 0.1 2.5e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB07753.1 - 3e-08 33.1 1.9 0.017 15.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.20 EEB07754.1 - 4.1e-77 258.8 0.1 4.8e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07754.1 - 1.2e-39 136.0 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07754.1 - 1.2e-08 34.3 0.0 4e-07 29.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEB07754.1 - 3e-06 26.7 0.1 5.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EEB07754.1 - 0.00012 21.1 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB07754.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1186 PF06685.6 EEB07754.1 - 0.044 12.9 0.2 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) DUF2082 PF09855.4 EEB07754.1 - 0.11 12.3 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) PAS_9 PF13426.1 EEB07755.1 - 1.3e-19 70.4 0.0 2.1e-15 56.9 0.0 3.6 3 1 0 3 3 3 2 PAS domain PAS PF00989.19 EEB07755.1 - 2.2e-09 37.0 0.0 0.037 13.8 0.0 4.4 3 2 1 4 4 4 3 PAS fold PAS_3 PF08447.6 EEB07755.1 - 6.3e-07 29.3 0.0 0.044 13.8 0.0 3.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EEB07755.1 - 0.0042 17.1 0.0 4.4 7.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EEB07755.1 - 0.017 15.0 0.0 3 7.8 0.0 3.2 3 0 0 3 3 3 0 PAS domain Ribosomal_S13 PF00416.17 EEB07756.1 - 4.9e-40 136.2 1.7 5.8e-40 136.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEB07756.1 - 0.0019 16.8 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EEB07756.1 - 0.0054 16.7 0.6 0.034 14.1 0.1 2.3 2 1 0 2 2 2 1 Helix-hairpin-helix motif Period_C PF12114.3 EEB07756.1 - 0.037 13.6 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2746 PF10874.3 EEB07756.1 - 0.097 12.8 0.6 0.73 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) PWI PF01480.12 EEB07757.1 - 8e-30 102.7 0.7 1.8e-29 101.6 0.1 1.9 2 0 0 2 2 2 1 PWI domain Pcc1 PF09341.5 EEB07758.2 - 1.6e-20 72.9 0.1 1.8e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 IncA PF04156.9 EEB07759.1 - 0.007 15.9 17.0 0.007 15.9 11.8 3.6 1 1 2 3 3 3 1 IncA protein Tctex-1 PF03645.8 EEB07759.1 - 0.12 12.2 1.7 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Tctex-1 family Baculo_PEP_C PF04513.7 EEB07759.1 - 2.4 7.9 17.3 0.65 9.8 0.4 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3453 PF11935.3 EEB07760.2 - 8.1e-49 166.1 0.1 2e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) MMS19_C PF12460.3 EEB07761.1 - 5e-93 312.0 18.9 5e-93 312.0 13.1 4.0 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EEB07761.1 - 4.7e-82 275.1 1.0 4.7e-82 275.1 0.7 3.4 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EEB07761.1 - 1.7e-08 34.7 5.3 0.00054 20.3 0.3 5.7 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 EEB07761.1 - 1.2e-06 28.7 4.4 0.0043 17.3 0.4 5.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EEB07761.1 - 0.0012 18.7 5.8 1.2 9.4 0.2 6.0 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EEB07761.1 - 0.0014 18.9 0.0 0.18 12.2 0.0 3.6 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region AgrB PF04647.10 EEB07761.1 - 0.003 16.6 0.5 0.0069 15.4 0.3 1.6 1 0 0 1 1 1 1 Accessory gene regulator B DUF2435 PF10363.4 EEB07761.1 - 0.8 9.6 5.9 1.4 8.8 0.0 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF2435) SPC25 PF06703.6 EEB07762.1 - 7.7e-23 80.8 2.3 8.8e-23 80.6 1.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Polysacc_synt_3 PF13440.1 EEB07762.1 - 0.01 15.3 0.3 0.013 15.0 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 EEB07763.1 - 0.0055 16.1 0.2 0.32 10.4 0.0 2.9 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_31 PF13847.1 EEB07763.1 - 0.056 13.0 0.0 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07763.1 - 0.094 12.4 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Actin PF00022.14 EEB07764.1 - 7.8e-30 103.5 0.0 1.3e-27 96.2 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEB07764.1 - 0.0034 16.0 0.0 0.22 10.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Ribosomal_S19 PF00203.16 EEB07765.1 - 2e-31 107.4 0.3 3.1e-31 106.8 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 EEB07766.1 - 4.3e-26 91.1 18.2 5.1e-26 90.8 12.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SNF2_N PF00176.18 EEB07768.2 - 1.1e-70 237.8 4.9 1.1e-70 237.8 3.4 2.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 EEB07768.2 - 4.1e-53 179.1 21.9 4.1e-53 179.1 15.2 4.8 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 EEB07768.2 - 1.9e-13 50.0 0.0 5.4e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SET PF00856.23 EEB07769.2 - 1.4e-21 77.4 0.3 1.4e-21 77.4 0.2 4.0 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EEB07769.2 - 6.6e-17 61.2 3.6 9.4e-17 60.7 1.1 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Apelin PF15360.1 EEB07769.2 - 6.1 7.1 8.6 0.17 12.1 0.9 2.2 2 0 0 2 2 2 0 APJ endogenous ligand RNR_inhib PF08591.5 EEB07770.2 - 1.9e-08 35.0 0.2 3e-08 34.4 0.1 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor DUF2458 PF10454.4 EEB07770.2 - 0.079 12.8 0.1 0.09 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) HSP70 PF00012.15 EEB07771.1 - 1.3e-60 205.0 4.6 4.8e-60 203.1 3.2 1.9 1 1 0 1 1 1 1 Hsp70 protein Amino_oxidase PF01593.19 EEB07772.1 - 1.1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEB07772.1 - 7.2e-11 41.9 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEB07772.1 - 3e-09 36.2 0.1 1.5e-06 27.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEB07772.1 - 3.6e-05 23.7 0.5 0.015 15.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB07772.1 - 0.00032 21.0 0.4 0.47 10.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEB07772.1 - 0.00064 18.8 0.1 0.0012 17.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EEB07772.1 - 0.0013 17.8 0.4 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEB07772.1 - 0.0026 16.6 0.2 0.0046 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EEB07772.1 - 0.0031 16.4 0.2 0.061 12.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EEB07772.1 - 0.0068 16.4 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEB07772.1 - 0.014 13.9 0.1 2.8 6.2 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EEB07772.1 - 0.018 13.7 0.1 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Mid1 PF12929.2 EEB07773.1 - 4.2e-123 411.2 14.0 5.5e-123 410.8 9.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EEB07773.1 - 0.22 11.8 5.2 0.43 10.9 0.8 2.8 2 1 0 2 2 2 0 Fz domain Pkinase PF00069.20 EEB07774.1 - 6.4e-68 228.7 0.1 9.3e-68 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07774.1 - 1.8e-52 178.0 0.0 2.8e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EEB07774.1 - 1.5e-14 54.1 0.0 4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EEB07774.1 - 1.4e-07 30.7 0.0 2.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EEB07774.1 - 5.3e-05 23.3 0.2 0.00016 21.8 0.1 1.8 1 0 0 1 1 1 1 PH domain Kdo PF06293.9 EEB07774.1 - 0.0012 17.9 0.4 0.002 17.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF458 PF04308.7 EEB07774.1 - 0.0078 15.9 0.8 0.75 9.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF458) APH PF01636.18 EEB07774.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family BRCA2 PF00634.13 EEB07774.1 - 0.1 11.8 0.2 0.25 10.6 0.1 1.7 1 0 0 1 1 1 0 BRCA2 repeat DEAD PF00270.24 EEB07775.1 - 4.7e-43 146.5 0.2 8.7e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB07775.1 - 1.6e-29 101.6 0.1 5.3e-29 99.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEB07775.1 - 0.00067 19.3 0.4 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 EEB07775.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EEB07775.1 - 0.016 13.6 0.0 0.15 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 EEB07775.1 - 0.023 14.2 0.3 0.059 12.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF155 PF02582.9 EEB07775.1 - 0.057 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 CMS1 PF14617.1 EEB07775.1 - 0.13 11.3 0.1 0.5 9.3 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EEB07775.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEB07775.1 - 0.19 11.8 0.7 1.3 9.1 0.5 2.2 1 1 0 1 1 1 0 AAA domain TrkH PF02386.11 EEB07777.1 - 3.5e-96 321.8 7.1 3.5e-96 321.8 4.9 1.9 2 0 0 2 2 2 1 Cation transport protein DUF3671 PF12420.3 EEB07777.1 - 8.9 6.3 8.0 1.3 9.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function ELO PF01151.13 EEB07778.1 - 1.3e-58 198.2 23.0 1.7e-58 197.8 15.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family GCP5-Mod21 PF14609.1 EEB07779.1 - 3.7e-279 927.4 9.9 2.2e-243 809.1 3.2 2.0 1 1 1 2 2 2 2 gamma-Tubulin ring complex non-core subunit mod21 NDK PF00334.14 EEB07780.1 - 1.5e-57 193.1 0.0 1.7e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CTP_transf_2 PF01467.21 EEB07782.2 - 1.7e-33 115.9 0.0 2.4e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Ribosomal_L14e PF01929.12 EEB07783.1 - 3.8e-29 100.8 3.8 5.8e-29 100.2 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 FlbD PF06289.6 EEB07783.1 - 0.038 13.3 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) KOW PF00467.24 EEB07783.1 - 1.3 8.8 5.4 2.9 7.7 3.7 1.6 1 0 0 1 1 1 0 KOW motif ubiquitin PF00240.18 EEB07784.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEB07784.1 - 8.5e-31 105.3 11.3 1.3e-30 104.6 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEB07784.1 - 4.1e-20 71.2 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB07784.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB07784.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB07784.1 - 0.007 16.2 0.1 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEB07784.1 - 0.011 15.9 0.1 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEB07784.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EEB07784.1 - 0.19 11.5 1.9 0.87 9.4 1.3 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S26e PF01283.14 EEB07786.1 - 6.7e-53 177.7 8.6 7.6e-53 177.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EEB07786.1 - 0.26 11.7 2.8 1.5 9.2 1.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEB07786.1 - 0.52 10.1 4.7 0.92 9.3 1.1 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.27 EEB07787.2 - 4.8e-54 178.4 20.8 3.1e-13 49.0 0.7 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ParA PF10609.4 EEB07787.2 - 3.9e-37 125.9 0.4 7.3e-37 125.1 0.3 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEB07787.2 - 8.2e-14 51.4 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain eIF2A PF08662.6 EEB07787.2 - 0.00025 20.8 0.0 0.56 9.8 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A MipZ PF09140.6 EEB07787.2 - 0.0014 17.7 0.0 0.0056 15.7 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ IKI3 PF04762.7 EEB07787.2 - 0.0036 15.2 0.1 0.0099 13.7 0.1 1.7 1 1 0 1 1 1 1 IKI3 family ArsA_ATPase PF02374.10 EEB07787.2 - 0.0043 16.1 0.1 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase Apc4_WD40 PF12894.2 EEB07787.2 - 0.015 14.7 0.0 8.9 5.9 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_31 PF13614.1 EEB07787.2 - 0.022 14.6 0.0 0.049 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEB07787.2 - 0.025 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TFIIIC_delta PF12657.2 EEB07787.2 - 0.027 14.1 1.5 2.2 7.9 0.0 3.6 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term AAA_22 PF13401.1 EEB07787.2 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nucleoporin_N PF08801.6 EEB07787.2 - 0.063 12.0 0.0 0.42 9.2 0.0 2.3 3 0 0 3 3 3 0 Nup133 N terminal like DUF258 PF03193.11 EEB07787.2 - 0.071 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PD40 PF07676.7 EEB07787.2 - 0.081 12.6 0.0 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 EEB07787.2 - 0.093 11.5 1.6 1.3 7.7 1.1 2.3 1 1 0 1 1 1 0 Coatomer WD associated region PPV_E2_C PF00511.12 EEB07787.2 - 0.35 10.8 1.6 8.2 6.4 0.0 3.0 3 0 0 3 3 3 0 E2 (early) protein, C terminal Porphobil_deam PF01379.15 EEB07788.1 - 4.2e-80 267.6 0.0 5.5e-80 267.3 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEB07788.1 - 5.9e-18 64.7 0.1 1e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MTH865 PF07747.6 EEB07788.1 - 0.068 12.8 0.4 6.3 6.5 0.0 3.3 4 0 0 4 4 4 0 MTH865-like family E1-E2_ATPase PF00122.15 EEB07789.1 - 2.1e-12 46.5 0.0 5.5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEB07789.1 - 3.7e-10 39.6 0.0 9.2e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEB07789.1 - 2.5e-06 27.7 0.1 7.9e-05 22.9 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB07789.1 - 7.6e-05 23.2 0.1 0.25 11.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEB07789.1 - 0.0083 15.7 0.5 0.017 14.7 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Maf1 PF09174.5 EEB07790.2 - 2.9e-50 170.6 0.8 3.4e-50 170.3 0.6 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF1754 PF08555.5 EEB07791.1 - 6.9e-08 32.9 22.3 6.9e-08 32.9 15.4 1.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PAPA-1 PF04795.7 EEB07791.1 - 0.011 16.3 12.6 0.018 15.7 0.9 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region LSM14 PF12701.2 EEB07791.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain NusG PF02357.14 EEB07791.1 - 0.12 12.6 4.2 0.092 12.9 1.7 1.5 1 1 1 2 2 2 0 Transcription termination factor nusG CMV_1a PF12467.3 EEB07791.1 - 2.8 8.2 9.2 4 7.7 6.4 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family FAM60A PF15396.1 EEB07791.1 - 3.8 7.1 9.1 4.7 6.9 6.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 EEB07791.1 - 6.9 5.7 14.3 8.9 5.4 9.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger COX16 PF14138.1 EEB07791.1 - 8 6.7 10.9 6.4 7.0 2.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 JAB PF01398.16 EEB07792.1 - 3.6e-36 123.3 0.3 1.6e-35 121.3 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEB07792.1 - 3e-23 82.0 1.7 5.5e-23 81.2 1.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EEB07792.1 - 3e-08 33.1 0.0 6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GCV_T PF01571.16 EEB07793.1 - 1.8e-65 220.2 0.0 2.3e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEB07793.1 - 2.6e-24 85.0 0.2 4.4e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CATSPERG PF15064.1 EEB07793.1 - 0.048 11.3 0.0 0.068 10.9 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma PS_Dcarbxylase PF02666.10 EEB07794.1 - 1.1e-55 188.0 0.0 1.8e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EEB07794.1 - 7.4e-15 54.5 0.1 2.6e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain NT-C2 PF10358.4 EEB07794.1 - 0.0042 16.5 4.0 1.4 8.4 0.0 4.3 3 1 0 3 3 3 1 N-terminal C2 in EEIG1 and EHBP1 proteins Glycos_transf_2 PF00535.21 EEB07795.1 - 6e-34 117.1 0.0 7.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEB07795.1 - 2.5e-14 53.6 0.0 3.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEB07795.1 - 3.1e-08 33.0 0.0 4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEB07795.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 FlaA PF04620.7 EEB07795.1 - 0.024 14.0 0.1 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa Glyco_trans_2_3 PF13632.1 EEB07795.1 - 0.061 13.0 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF4471 PF14740.1 EEB07795.1 - 0.11 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) S10_plectin PF03501.10 EEB07796.1 - 3.2e-43 145.4 0.1 3.9e-43 145.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EEB07797.1 - 4.4e-38 130.5 0.7 6.4e-38 129.9 0.1 1.6 2 0 0 2 2 2 1 Telomere stability and silencing AAA PF00004.24 EEB07798.1 - 2.7e-47 160.2 0.0 8.1e-41 139.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEB07798.1 - 3.7e-08 33.4 0.0 1.6e-05 24.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEB07798.1 - 5.8e-06 26.4 0.7 4.9e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EEB07798.1 - 1.1e-05 24.9 0.0 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EEB07798.1 - 6e-05 23.2 2.7 0.008 16.3 0.1 4.6 5 1 0 5 5 4 1 AAA domain AAA_5 PF07728.9 EEB07798.1 - 0.00072 19.3 0.0 0.0039 16.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EEB07798.1 - 0.0018 18.3 0.0 0.68 9.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EEB07798.1 - 0.0029 17.3 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EEB07798.1 - 0.0032 17.6 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Bromodomain PF00439.20 EEB07798.1 - 0.0066 16.3 0.1 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.1 EEB07798.1 - 0.0071 16.2 0.0 0.032 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEB07798.1 - 0.0078 15.8 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB07798.1 - 0.0091 16.3 0.0 0.062 13.6 0.0 2.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB07798.1 - 0.012 15.9 0.1 0.08 13.2 0.0 2.5 2 0 0 2 2 1 0 ABC transporter AAA_17 PF13207.1 EEB07798.1 - 0.015 16.0 4.0 0.054 14.3 0.0 3.5 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EEB07798.1 - 0.02 14.3 0.2 0.089 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEB07798.1 - 0.042 13.0 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EEB07798.1 - 0.05 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EEB07798.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EEB07798.1 - 0.066 12.6 0.0 1.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.8 EEB07798.1 - 0.07 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 EEB07798.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EEB07798.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3336 PF11815.3 EEB07799.1 - 1.1e-41 141.7 2.1 1.9e-41 140.9 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEB07799.1 - 1.8e-17 63.9 0.0 4.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1744 PF08490.7 EEB07800.2 - 6.8e-120 400.2 0.1 1.1e-119 399.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EEB07800.2 - 1.7e-67 227.6 4.3 4.1e-67 226.3 3.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EEB07800.2 - 3.9e-22 78.6 0.2 9.3e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EEB07800.2 - 8.3e-10 38.5 0.1 2.6e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EEB07800.2 - 8.6e-05 22.3 0.1 0.00068 19.4 0.0 2.7 2 0 0 2 2 2 1 RNase_H superfamily UNC-50 PF05216.8 EEB07801.1 - 4.8e-73 245.1 16.6 5.9e-73 244.8 11.5 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1625 PF07787.7 EEB07801.1 - 8.8 5.4 9.2 11 5.2 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) PDCD2_C PF04194.8 EEB07802.1 - 3.1e-27 95.1 0.1 3.1e-27 95.1 0.0 2.3 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain VHS PF00790.14 EEB07803.1 - 3.1e-44 150.0 0.0 9.1e-43 145.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 EEB07803.1 - 1.7e-15 57.3 0.4 4.4e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.9 EEB07803.1 - 7.1e-05 22.7 0.6 0.00034 20.5 0.4 2.2 1 0 0 1 1 1 1 GAT domain DUF2321 PF10083.4 EEB07803.1 - 0.017 14.5 0.5 0.056 12.9 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) PIG-P PF08510.7 EEB07804.1 - 3.6e-33 113.8 7.1 9.8e-33 112.4 4.9 1.7 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.7 EEB07804.1 - 0.032 14.5 7.6 0.054 13.7 5.3 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-ISL3 PF14690.1 EEB07804.1 - 0.052 13.5 0.1 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF1469 PF07332.6 EEB07804.1 - 0.42 10.3 1.4 0.61 9.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF1077 PF06417.7 EEB07805.1 - 1.7e-47 159.8 6.5 2.3e-47 159.4 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TUDOR PF00567.19 EEB07806.1 - 2.3e-05 24.2 0.0 4.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 EEB07806.1 - 0.00035 20.3 0.0 0.00087 19.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.5 EEB07806.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Agenet PF05641.7 EEB07806.1 - 0.05 13.7 1.4 0.16 12.1 1.0 1.9 1 1 0 1 1 1 0 Agenet domain Alpha-amylase PF00128.19 EEB07807.1 - 2.3e-24 86.3 13.4 2.4e-23 83.0 2.4 3.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEB07807.1 - 1.3e-18 67.3 0.1 2.5e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB07807.1 - 5.8e-07 29.0 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cid2 PF09774.4 EEB07808.1 - 7.7e-28 97.4 4.8 9e-28 97.2 3.3 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 UQ_con PF00179.21 EEB07809.1 - 9.6e-17 60.7 0.0 1e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEB07809.1 - 0.039 13.8 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain HSP20 PF00011.16 EEB07810.1 - 5.4e-20 71.1 0.1 6.3e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EEB07810.1 - 4.3e-05 23.9 0.0 7.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 EEB07810.1 - 0.00037 20.0 0.1 0.0005 19.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) NARP1 PF12569.3 EEB07811.1 - 6.8e-180 599.2 21.7 6.8e-180 599.2 15.0 1.9 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EEB07811.1 - 2e-09 36.9 28.3 0.0013 18.3 1.0 7.4 7 1 0 7 7 7 3 TPR repeat TPR_2 PF07719.12 EEB07811.1 - 1.7e-08 33.7 29.0 0.23 11.4 0.0 10.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEB07811.1 - 9.8e-06 25.8 34.8 0.0012 19.1 0.1 7.4 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEB07811.1 - 2e-05 25.1 38.6 0.079 13.6 2.5 8.8 8 3 2 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEB07811.1 - 3.3e-05 23.7 21.9 0.073 13.0 0.2 7.1 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB07811.1 - 5.1e-05 23.1 6.1 3 8.2 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEB07811.1 - 8.4e-05 22.8 22.6 0.96 10.2 0.3 9.0 7 3 4 11 11 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB07811.1 - 0.0048 16.5 22.3 0.29 11.0 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB07811.1 - 0.017 14.9 8.5 4.9 7.0 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SpoU_sub_bind PF08032.7 EEB07811.1 - 0.63 10.2 4.6 44 4.3 0.0 4.5 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding TPR_1 PF00515.23 EEB07811.1 - 1.1 9.0 25.0 0.94 9.1 0.4 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.4 EEB07812.1 - 4.5e-53 179.5 0.2 5.4e-53 179.3 0.2 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family Myb_DNA-binding PF00249.26 EEB07813.2 - 4e-21 74.8 2.4 2.5e-12 46.6 0.5 4.5 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB07813.2 - 4.5e-19 68.3 11.0 2.9e-15 56.0 2.2 4.5 3 1 1 4 4 4 2 Myb-like DNA-binding domain Pkinase PF00069.20 EEB07814.1 - 1.5e-74 250.4 0.0 1.8e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07814.1 - 3.5e-32 111.5 0.0 4.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07814.1 - 7.1e-06 25.1 0.0 1.6e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEB07814.1 - 0.0025 17.5 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEB07814.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEB07814.1 - 0.019 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family UvdE PF03851.9 EEB07814.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 UV-endonuclease UvdE HEM4 PF02602.10 EEB07815.1 - 9.4e-29 100.2 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Fig1 PF12351.3 EEB07816.2 - 2.6e-08 33.9 7.4 2.6e-08 33.9 5.1 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEB07816.2 - 1.7e-05 24.4 16.4 2.6e-05 23.8 11.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Cpn60_TCP1 PF00118.19 EEB07818.1 - 1.5e-143 478.9 3.0 1.8e-143 478.7 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bromodomain PF00439.20 EEB07819.1 - 3.1e-17 62.2 0.0 8.7e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EEB07819.1 - 2e-11 43.4 0.1 5.4e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated UPF0179 PF03684.8 EEB07819.1 - 0.07 12.7 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) Zn_clus PF00172.13 EEB07823.2 - 5.9e-07 29.2 14.2 1.5e-06 27.9 9.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 EEB07824.1 - 3.1e-25 88.5 0.0 3.7e-24 84.9 0.0 1.9 2 0 0 2 2 2 2 Transferase family AA_permease_2 PF13520.1 EEB07825.1 - 4.4e-48 163.8 53.6 5.4e-48 163.5 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07825.1 - 6.9e-15 54.3 45.7 9.5e-15 53.8 31.7 1.2 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.8 EEB07826.1 - 2.6e-20 72.9 4.3 3.6e-20 72.4 3.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF202 PF02656.10 EEB07826.1 - 0.84 9.9 4.1 26 5.1 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Gp_dh_C PF02800.15 EEB07828.1 - 1.2e-74 248.9 0.1 1.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEB07828.1 - 1.3e-61 207.0 0.1 2.6e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EEB07828.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EEB07828.1 - 0.024 14.5 1.8 0.079 12.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EEB07828.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.16 EEB07829.1 - 5.2e-110 368.0 43.2 6.4e-110 367.7 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB07829.1 - 1.2e-33 116.2 46.8 1.6e-33 115.9 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07830.2 - 3.8e-114 381.6 38.7 4.5e-114 381.4 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB07830.2 - 7.3e-29 100.5 41.2 9.8e-29 100.1 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease NRDD PF13597.1 EEB07831.1 - 1.3e-202 673.7 0.0 1.5e-202 673.5 0.0 1.0 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Melibiase PF02065.13 EEB07832.1 - 1.3e-34 119.5 0.0 4e-18 65.3 0.0 2.1 1 1 1 2 2 2 2 Melibiase GalKase_gal_bdg PF10509.4 EEB07833.2 - 1.3e-20 72.4 0.0 2.6e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EEB07833.2 - 1.3e-15 57.1 0.3 1.3e-15 57.1 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEB07833.2 - 6.5e-13 48.6 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.15 EEB07834.1 - 2.9e-65 220.3 0.2 4.5e-65 219.7 0.2 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EEB07834.1 - 3.8e-49 167.2 0.1 8.6e-49 166.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEB07834.1 - 3.9e-17 61.8 0.1 8.8e-17 60.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEB07834.1 - 4.7e-16 58.5 0.0 1.2e-14 53.8 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EEB07834.1 - 2.3e-13 49.6 0.0 4.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEB07834.1 - 1.5e-09 38.0 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEB07834.1 - 4e-09 35.7 0.1 8.5e-08 31.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEB07834.1 - 1.7e-08 34.5 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB07834.1 - 2.1e-07 30.8 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 EEB07834.1 - 0.014 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EEB07834.1 - 0.02 13.8 0.1 0.034 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NmrA PF05368.8 EEB07834.1 - 0.034 13.3 0.8 0.098 11.8 0.5 1.9 1 1 0 1 1 1 0 NmrA-like family RRM_1 PF00076.17 EEB07835.1 - 3.7e-14 52.1 0.0 7.3e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB07835.1 - 9.6e-14 51.1 0.0 2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB07835.1 - 2.5e-09 36.8 0.1 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GalP_UDP_transf PF01087.17 EEB07836.1 - 3.3e-64 216.3 0.1 6.2e-64 215.4 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EEB07836.1 - 8.1e-62 207.6 0.2 1.4e-61 206.8 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 EEB07836.1 - 0.012 15.7 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EEB07836.1 - 0.023 15.2 0.0 0.076 13.5 0.0 1.9 2 0 0 2 2 2 0 HIT domain AA_permease PF00324.16 EEB07837.1 - 2.9e-111 372.1 43.5 3.6e-111 371.8 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB07837.1 - 4.6e-25 88.0 46.1 9.2e-25 87.0 31.8 1.5 1 1 1 2 2 2 1 Amino acid permease Zn_clus PF00172.13 EEB07838.2 - 6.2e-07 29.2 10.3 1.2e-06 28.2 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2959 PF11172.3 EEB07838.2 - 0.046 13.4 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) RTA1 PF04479.8 EEB07839.1 - 1.7e-47 161.7 6.7 2.5e-47 161.2 4.6 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2678 PF10856.3 EEB07839.1 - 0.39 10.4 6.1 0.3 10.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Sugar_tr PF00083.19 EEB07840.2 - 1.8e-103 346.5 22.4 2.2e-103 346.2 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB07840.2 - 5.7e-16 58.1 33.1 1e-12 47.4 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 EEB07841.1 - 1.7e-13 50.4 6.5 1.7e-13 50.4 4.5 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EEB07841.1 - 0.051 12.5 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Epimerase PF01370.16 EEB07842.1 - 7.5e-19 68.1 0.0 1.3e-18 67.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEB07842.1 - 6.2e-12 44.8 0.0 1e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEB07842.1 - 5.3e-09 35.3 0.0 1.2e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEB07842.1 - 1.7e-08 34.6 0.0 6.4e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEB07842.1 - 1.9e-05 23.7 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EEB07842.1 - 0.0027 16.9 0.2 0.009 15.2 0.0 1.9 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EEB07842.1 - 0.1 12.5 0.2 0.98 9.3 0.1 2.5 2 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 EEB07843.1 - 2e-12 47.0 0.1 2.2e-11 43.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB07843.1 - 8.1e-07 29.2 0.0 1.5e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEB07843.1 - 0.00023 20.4 0.1 0.00038 19.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EEB07843.1 - 0.00064 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EEB07843.1 - 0.0035 16.3 0.2 0.2 10.5 0.2 2.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EEB07843.1 - 0.011 14.4 0.1 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEB07843.1 - 0.046 12.6 0.1 0.36 9.6 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain MFS_1 PF07690.11 EEB07844.1 - 1.4e-27 96.3 39.2 6e-26 90.9 9.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EEB07845.1 - 6.3e-31 106.3 2.0 1e-30 105.6 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB07845.1 - 2.3e-17 62.7 0.0 3.7e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB07845.1 - 1.9e-07 32.0 0.0 3.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEB07845.1 - 2e-05 23.8 0.1 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEB07845.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EEB07845.1 - 0.0024 17.8 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 EEB07845.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EEB07845.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EEB07845.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Iron_permease PF04120.7 EEB07848.1 - 1.8e-44 150.5 12.2 1.8e-16 59.9 0.2 4.2 4 0 0 4 4 4 4 Low affinity iron permease HD-ZIP_N PF04618.7 EEB07848.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 HD-ZIP protein N terminus Cys_Met_Meta_PP PF01053.15 EEB07850.1 - 5.5e-154 512.1 0.0 6.2e-154 511.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEB07850.1 - 8.6e-14 51.3 0.1 1.5e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEB07850.1 - 6.6e-13 48.3 0.0 1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEB07850.1 - 2.1e-07 30.0 0.2 3.5e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEB07850.1 - 0.00014 21.1 0.0 0.00046 19.4 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EEB07850.1 - 0.00017 19.9 0.3 0.00045 18.6 0.2 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase TNV_CP PF03898.8 EEB07850.1 - 0.015 14.3 0.2 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein SelA PF03841.8 EEB07850.1 - 0.02 13.6 0.5 0.088 11.5 0.3 1.8 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase GDC-P PF02347.11 EEB07850.1 - 0.025 13.2 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 EEB07850.1 - 0.027 12.9 0.0 0.041 12.3 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Methyltransf_11 PF08241.7 EEB07851.1 - 6.8e-18 64.9 0.0 8.2e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB07851.1 - 1.9e-12 47.0 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07851.1 - 6e-12 46.1 0.0 9.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB07851.1 - 1.8e-11 44.0 0.0 2.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB07851.1 - 3.5e-11 43.3 0.0 5.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB07851.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB07851.1 - 5.3e-07 29.6 0.0 9.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEB07851.1 - 8.2e-06 25.1 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EEB07851.1 - 8.9e-06 25.4 0.0 1.7e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.7 EEB07851.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EEB07851.1 - 0.0053 15.8 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EEB07851.1 - 0.0095 15.3 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DIL PF01843.14 EEB07852.1 - 8.6e-15 54.5 2.0 1.4e-13 50.6 1.4 2.3 1 1 0 1 1 1 1 DIL domain HIG_1_N PF04588.8 EEB07853.1 - 2.6e-21 75.0 1.1 4.2e-21 74.4 0.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region YrhK PF14145.1 EEB07853.1 - 0.42 10.3 1.7 3.7 7.2 1.3 1.9 1 1 0 1 1 1 0 YrhK-like protein DUF4570 PF15134.1 EEB07854.1 - 0.081 12.7 1.2 0.094 12.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Anti-adapt_IraP PF10796.4 EEB07854.1 - 0.1 12.9 0.4 0.15 12.4 0.3 1.4 1 1 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Baculo_PEP_C PF04513.7 EEB07854.1 - 0.14 11.9 1.0 0.15 11.8 0.7 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 EEB07854.1 - 0.49 10.2 4.5 0.2 11.4 0.8 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding tRNA-synt_2b PF00587.20 EEB07855.1 - 4.3e-21 75.2 0.0 6.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEB07855.1 - 1.2e-12 47.7 3.9 2.3e-12 46.8 2.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.1 EEB07855.1 - 0.0028 17.5 1.7 0.0068 16.3 1.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 PseudoU_synth_1 PF01416.15 EEB07856.1 - 3e-34 117.6 0.0 3.4e-20 72.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase zf-Mss51 PF13824.1 EEB07857.1 - 6.3e-20 70.7 1.4 1.4e-19 69.7 0.9 1.7 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 EEB07857.1 - 4.4 7.5 8.2 0.22 11.6 1.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) PS_Dcarbxylase PF02666.10 EEB07858.1 - 1.3e-70 236.8 0.1 7.6e-70 234.3 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylserine decarboxylase Sds3 PF08598.6 EEB07859.1 - 1.1e-25 90.3 8.2 1.4e-25 90.0 5.7 1.1 1 0 0 1 1 1 1 Sds3-like OmpH PF03938.9 EEB07859.1 - 6.7 6.6 11.5 3 7.7 3.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cyt-b5 PF00173.23 EEB07860.2 - 2.4e-12 46.4 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain His_Phos_1 PF00300.17 EEB07862.1 - 6.3e-21 75.1 0.0 7.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AcetylCoA_hyd_C PF13336.1 EEB07863.1 - 8.3e-40 135.9 0.0 1.2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EEB07863.1 - 4.3e-25 88.6 0.0 8.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AA_permease_2 PF13520.1 EEB07864.1 - 7.1e-41 140.1 45.4 8.9e-41 139.8 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB07864.1 - 2.4e-19 69.0 41.3 3.3e-19 68.5 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3464 PF11947.3 EEB07864.1 - 0.54 9.7 3.2 1.1 8.6 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GFA PF04828.9 EEB07865.1 - 0.08 12.8 7.5 0.63 10.0 0.6 3.7 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DJ-1_PfpI PF01965.19 EEB07866.1 - 1.8e-29 102.0 0.3 2.5e-29 101.6 0.2 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEB07866.1 - 4.3e-05 22.9 0.1 0.0001 21.7 0.1 1.7 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family PH PF00169.24 EEB07867.1 - 9.8e-05 22.5 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 PH domain MOZ_SAS PF01853.13 EEB07868.1 - 4.8e-90 299.8 1.9 6.7e-90 299.3 1.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEB07868.1 - 8.4e-19 67.0 1.2 1.7e-18 66.0 0.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EEB07868.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IF2_N PF04760.10 EEB07868.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-H2C2_5 PF13909.1 EEB07868.1 - 0.53 10.6 5.5 2.1 8.7 3.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Helicase_C PF00271.26 EEB07869.1 - 4.9e-10 39.1 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EEB07869.1 - 5.4e-10 38.5 0.3 5.4e-10 38.5 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal VWA_2 PF13519.1 EEB07870.2 - 1.7e-13 51.0 0.0 2.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EEB07870.2 - 2.1e-09 37.2 0.1 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EEB07870.2 - 7.6e-06 25.7 0.2 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EEB07870.2 - 0.0081 15.6 2.0 0.021 14.3 1.4 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif RNase_T PF00929.19 EEB07871.1 - 1.1e-25 90.7 0.0 1.8e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease ParA PF10609.4 EEB07872.1 - 1e-36 124.6 0.1 1.7e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEB07872.1 - 6e-16 58.4 0.0 9.1e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EEB07872.1 - 4.1e-07 29.3 0.3 8e-06 25.1 0.0 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 EEB07872.1 - 5.5e-06 26.4 0.0 4.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EEB07872.1 - 1.2e-05 24.4 0.0 2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EEB07872.1 - 0.00051 19.7 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEB07872.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEB07872.1 - 0.0057 15.8 0.1 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 EEB07872.1 - 0.018 14.4 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EEB07872.1 - 0.038 13.1 0.0 0.15 11.1 0.0 1.9 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.1 EEB07872.1 - 0.085 12.7 0.0 0.33 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 EEB07872.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein AAA_17 PF13207.1 EEB07872.1 - 0.091 13.5 0.1 0.14 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEB07872.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 EEB07872.1 - 0.098 11.5 0.0 1.2 7.9 0.0 2.2 2 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SIS_2 PF13580.1 EEB07872.1 - 0.12 12.0 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 SIS domain Zn_Tnp_IS1595 PF12760.2 EEB07872.1 - 0.14 11.9 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 1 0 Transposase zinc-ribbon domain eIF-3_zeta PF05091.7 EEB07873.1 - 5.6e-188 625.7 0.0 6.4e-188 625.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_34 PF05637.7 EEB07874.1 - 5.5e-70 235.5 0.1 6.6e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MutS_IV PF05190.13 EEB07874.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA PF00004.24 EEB07875.1 - 5.4e-49 165.7 0.0 1.8e-44 151.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEB07875.1 - 1.2e-05 26.0 0.1 7.2e-05 23.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEB07875.1 - 2e-05 24.6 0.9 0.00066 19.7 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEB07875.1 - 4.3e-05 23.6 0.0 0.00065 19.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEB07875.1 - 6.7e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EEB07875.1 - 0.00019 20.2 0.0 0.00034 19.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EEB07875.1 - 0.0002 21.2 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEB07875.1 - 0.00087 19.0 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain DUF815 PF05673.8 EEB07875.1 - 0.00095 18.1 0.0 0.0028 16.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EEB07875.1 - 0.00095 18.6 0.0 0.0034 16.8 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EEB07875.1 - 0.0011 18.4 0.8 0.058 12.8 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEB07875.1 - 0.0012 18.5 0.0 0.005 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEB07875.1 - 0.0023 17.8 0.0 0.015 15.1 0.0 2.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEB07875.1 - 0.004 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EEB07875.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEB07875.1 - 0.0065 15.6 0.2 0.016 14.3 0.1 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEB07875.1 - 0.0065 15.5 0.0 0.018 14.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EEB07875.1 - 0.0081 15.7 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEB07875.1 - 0.012 15.2 0.2 0.48 10.0 0.0 3.2 2 1 0 3 3 3 0 NACHT domain KaiC PF06745.8 EEB07875.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EEB07875.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EEB07875.1 - 0.018 13.9 0.0 0.04 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EEB07875.1 - 0.027 14.0 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LRR_1 PF00560.28 EEB07875.1 - 0.03 14.3 0.8 78 3.9 0.0 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat PhoH PF02562.11 EEB07875.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EEB07875.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain HEAT PF02985.17 EEB07876.1 - 4.9e-22 75.9 19.0 1.8e-05 24.4 0.0 12.8 13 0 0 13 13 13 3 HEAT repeat HEAT_EZ PF13513.1 EEB07876.1 - 9.7e-21 73.6 27.3 3.1e-08 33.8 0.1 10.6 9 3 4 13 13 12 5 HEAT-like repeat HEAT_2 PF13646.1 EEB07876.1 - 3.3e-19 68.9 22.6 3e-08 33.8 0.2 8.5 6 2 7 13 13 12 7 HEAT repeats RIX1 PF08167.7 EEB07876.1 - 1.4e-12 47.6 0.0 0.015 15.0 0.0 5.5 4 1 1 5 5 5 3 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EEB07876.1 - 1.5e-10 41.3 1.9 0.00044 20.5 0.0 6.3 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EEB07876.1 - 2e-07 29.7 0.1 0.0015 16.9 0.0 3.8 3 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 EEB07876.1 - 5.4e-07 29.1 0.4 0.032 13.6 0.1 6.3 5 3 3 8 8 8 1 CLASP N terminal Arm PF00514.18 EEB07876.1 - 1.2e-05 24.9 2.4 1.2 9.0 0.0 7.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EEB07876.1 - 3.1e-05 23.8 0.1 1.7 8.4 0.0 5.4 4 4 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EEB07876.1 - 0.0001 22.1 1.0 0.42 10.5 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) TFCD_C PF12612.3 EEB07876.1 - 0.00041 19.8 1.3 0.029 13.7 0.0 3.9 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal DUF3385 PF11865.3 EEB07876.1 - 0.00063 19.7 0.1 1.4 8.7 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.2 EEB07876.1 - 0.013 15.4 0.8 60 3.7 0.3 4.7 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion IBN_N PF03810.14 EEB07876.1 - 0.045 13.6 0.1 6.8 6.6 0.0 4.0 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF4042 PF13251.1 EEB07876.1 - 0.12 11.8 5.8 8.4 5.8 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Nif11 PF07862.6 EEB07876.1 - 0.74 9.8 3.5 1.8 8.5 1.2 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Glucan_synthase PF02364.10 EEB07877.2 - 0 1450.0 0.0 0 1449.3 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEB07877.2 - 2.2e-33 114.6 0.2 6.1e-33 113.2 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Mog1 PF04603.7 EEB07878.2 - 8.1e-34 116.5 0.0 1e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rhomboid PF01694.17 EEB07879.2 - 2.4e-19 69.7 8.7 3.2e-19 69.4 6.0 1.2 1 0 0 1 1 1 1 Rhomboid family Pep3_Vps18 PF05131.9 EEB07880.1 - 1.4e-30 105.6 1.7 2e-28 98.6 0.0 3.6 4 0 0 4 4 4 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EEB07880.1 - 4.2e-07 30.1 1.8 1.3e-06 28.5 1.3 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EEB07880.1 - 0.00013 21.6 10.5 0.00015 21.4 1.0 3.6 3 1 1 4 4 4 1 Region in Clathrin and VPS P16-Arc PF04699.9 EEB07880.1 - 0.014 15.3 1.1 0.099 12.6 0.8 2.4 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) zf-RING_2 PF13639.1 EEB07880.1 - 0.21 11.4 7.6 0.53 10.1 5.3 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EEB07880.1 - 0.24 11.1 6.0 0.5 10.1 4.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEB07880.1 - 0.4 10.7 7.5 0.85 9.7 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB07880.1 - 1.8 8.2 6.2 4.7 6.9 4.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BRE1 PF08647.6 EEB07881.1 - 3e-15 55.9 5.1 3e-15 55.9 3.6 5.5 6 2 1 7 7 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EEB07881.1 - 7.9e-05 22.6 14.2 0.00016 21.6 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB07881.1 - 8.6e-05 22.2 11.2 0.00018 21.2 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB07881.1 - 8.7e-05 22.1 11.8 0.00015 21.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ADIP PF11559.3 EEB07881.1 - 0.00019 21.3 2.1 0.00019 21.3 1.4 6.3 3 1 4 7 7 6 1 Afadin- and alpha -actinin-Binding zf-RING_UBOX PF13445.1 EEB07881.1 - 0.00056 19.5 5.5 0.0019 17.9 3.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EEB07881.1 - 0.00073 19.1 14.9 0.0016 18.0 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07881.1 - 0.0079 15.9 13.3 0.016 14.9 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EEB07881.1 - 0.01 15.6 4.5 0.022 14.5 3.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EEB07881.1 - 0.029 14.2 9.7 0.087 12.7 6.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EEB07881.1 - 0.042 13.4 10.8 0.099 12.2 7.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEB07881.1 - 0.059 13.4 9.4 0.13 12.3 6.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EEB07881.1 - 0.31 10.6 6.4 0.76 9.3 4.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF778 PF05608.7 EEB07881.1 - 3.4 7.6 4.6 21 5.0 2.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Myb_DNA-binding PF00249.26 EEB07882.2 - 4.9e-06 26.5 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF458 PF04308.7 EEB07882.2 - 0.0065 16.2 0.3 0.025 14.3 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF458) DUF2431 PF10354.4 EEB07883.1 - 2.4e-56 190.2 0.1 3.4e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EEB07883.1 - 2.4e-05 24.3 0.0 4.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB07883.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EEB07883.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M28 PF04389.12 EEB07884.1 - 9.7e-35 119.9 0.1 1.5e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEB07884.1 - 0.001 18.6 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EEB07884.1 - 0.054 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase BAR PF03114.13 EEB07885.2 - 6.6e-34 117.4 9.7 1.2e-33 116.5 6.7 1.4 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EEB07885.2 - 5.2e-08 32.3 0.0 9.4e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEB07885.2 - 3.6e-07 29.4 0.0 7.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.4 EEB07885.2 - 2.6e-05 23.3 6.3 2.6e-05 23.3 4.4 2.0 1 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.12 EEB07885.2 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_11 PF13414.1 EEB07885.2 - 0.025 14.2 0.4 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 TPR repeat UCH PF00443.24 EEB07885.2 - 0.077 12.1 1.9 0.12 11.4 1.3 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Prefoldin_3 PF13758.1 EEB07885.2 - 0.22 11.2 5.1 0.26 11.0 1.5 2.5 3 0 0 3 3 3 0 Prefoldin subunit Herpes_UL92 PF03048.9 EEB07885.2 - 0.28 10.7 3.2 1.4 8.4 0.1 2.9 1 1 2 3 3 3 0 UL92 family Myosin_head PF00063.16 EEB07886.2 - 5.6e-238 791.4 11.3 5.6e-238 791.4 7.9 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EEB07886.2 - 5.2e-18 64.8 1.4 5.2e-18 64.8 0.9 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EEB07886.2 - 4.6e-12 44.4 20.0 0.0097 15.4 0.1 5.6 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.14 EEB07886.2 - 0.00048 19.7 2.9 0.0011 18.5 2.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EEB07886.2 - 0.0086 16.2 0.0 0.046 13.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain eIF-6 PF01912.13 EEB07887.1 - 8.7e-83 276.2 0.3 1.1e-82 276.0 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family Ureidogly_hydro PF04115.7 EEB07888.1 - 3.6e-40 136.9 0.0 4.2e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Polysacc_deac_1 PF01522.16 EEB07889.1 - 8e-17 61.0 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase RNA_pol PF00940.14 EEB07890.1 - 7.4e-158 525.2 0.0 1.1e-157 524.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EEB07890.1 - 8e-72 242.1 0.0 2.3e-71 240.6 0.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF1951 PF09188.5 EEB07890.1 - 0.031 14.2 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Kei1 PF08552.6 EEB07891.2 - 7.7e-38 130.0 7.4 1.3e-37 129.3 5.1 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 PsbI PF02532.9 EEB07891.2 - 0.0076 15.8 1.8 0.025 14.1 1.3 1.9 1 0 0 1 1 1 1 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF3321 PF11968.3 EEB07892.1 - 9.7e-66 221.5 0.0 1.3e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) AAA_17 PF13207.1 EEB07893.1 - 1.3e-07 32.4 0.0 3.4e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EEB07893.1 - 6.6e-07 29.0 0.0 2.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EEB07893.1 - 8.3e-05 22.8 0.0 0.00022 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEB07893.1 - 0.00074 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.6 EEB07893.1 - 0.00095 17.9 0.1 0.0039 15.9 0.0 1.9 2 1 1 3 3 3 1 PrkA AAA domain KAP_NTPase PF07693.9 EEB07893.1 - 0.0011 18.0 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain MobB PF03205.9 EEB07893.1 - 0.002 17.8 0.1 0.0084 15.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EEB07893.1 - 0.0024 17.0 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EEB07893.1 - 0.0035 17.6 0.2 0.022 15.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter NTPase_1 PF03266.10 EEB07893.1 - 0.0038 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_28 PF13521.1 EEB07893.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEB07893.1 - 0.0065 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EEB07893.1 - 0.0066 16.1 0.1 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEB07893.1 - 0.0083 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB07893.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEB07893.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EEB07893.1 - 0.019 13.7 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 EEB07893.1 - 0.033 14.0 0.0 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEB07893.1 - 0.045 14.0 0.0 0.097 12.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.10 EEB07893.1 - 0.053 12.1 0.0 0.087 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 EEB07893.1 - 0.054 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.14 EEB07893.1 - 0.075 12.4 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EEB07893.1 - 0.079 12.4 0.2 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EEB07893.1 - 0.13 10.9 0.1 0.29 9.7 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.1 EEB07893.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EEB07893.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain FA_hydroxylase PF04116.8 EEB07894.1 - 1.2e-15 57.9 22.0 1.2e-15 57.9 15.2 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Sprouty PF05210.8 EEB07894.1 - 0.16 11.9 1.5 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Sprouty protein (Spry) DUF3660 PF12398.3 EEB07895.1 - 0.02 14.7 0.1 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 Receptor serine/threonine kinase DUF2011 PF09428.5 EEB07896.1 - 1.2e-13 51.0 5.6 1.3e-12 47.7 3.8 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Calpain_inhib PF00748.14 EEB07896.1 - 0.033 14.5 0.6 0.033 14.5 0.4 1.9 2 0 0 2 2 2 0 Calpain inhibitor PRP4 PF08799.6 EEB07896.1 - 0.15 11.3 2.2 0.25 10.6 1.5 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like VGCC_beta4Aa_N PF12052.3 EEB07896.1 - 0.7 9.8 6.9 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal RabGAP-TBC PF00566.13 EEB07897.1 - 1.5e-24 86.6 16.3 2.8e-18 66.1 6.2 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 EEB07897.1 - 1.1e-06 28.0 0.0 0.025 13.8 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3548) Peptidase_M18 PF02127.10 EEB07898.1 - 4.5e-177 588.8 0.0 5.1e-177 588.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EEB07898.1 - 8.3e-05 21.4 0.0 0.0023 16.7 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase EAP30 PF04157.11 EEB07899.1 - 0.1 11.7 18.6 0.19 10.8 0.8 2.9 2 0 0 2 2 2 0 EAP30/Vps36 family DUF1899 PF08953.6 EEB07899.1 - 0.13 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Fmp27_WPPW PF10359.4 EEB07899.1 - 1.4 7.2 24.7 0.021 13.2 8.1 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ERG4_ERG24 PF01222.12 EEB07900.1 - 2.4e-175 583.2 21.6 2.7e-175 583.0 14.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Cofilin_ADF PF00241.15 EEB07901.1 - 5e-46 155.7 0.3 5.6e-46 155.5 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Hus1 PF04005.7 EEB07902.2 - 1.9e-84 283.0 1.1 2.2e-84 282.8 0.8 1.0 1 0 0 1 1 1 1 Hus1-like protein WD40 PF00400.27 EEB07903.1 - 1.6e-24 84.7 6.4 5.9e-06 25.9 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EEB07903.1 - 0.00022 19.5 0.1 0.18 9.9 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SUKH_5 PF14567.1 EEB07903.1 - 0.031 13.7 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall PBP1_TM PF14812.1 EEB07903.1 - 0.23 11.8 5.7 0.59 10.4 3.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1754 PF08555.5 EEB07903.1 - 0.25 11.9 6.2 0.56 10.8 4.3 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Nha1_C PF08619.5 EEB07903.1 - 0.72 9.0 9.5 1.1 8.4 6.6 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Prenyltrans PF00432.16 EEB07904.1 - 2.4e-33 113.3 5.9 4e-13 48.6 0.1 5.0 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEB07904.1 - 7.8e-18 64.9 0.0 3.4e-08 33.8 0.0 3.4 1 1 2 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEB07904.1 - 1.5e-08 34.6 0.0 0.0037 17.2 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase-like DnaJ PF00226.26 EEB07905.1 - 1.4e-15 56.7 0.7 3.1e-15 55.6 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EEB07906.1 - 7.5e-05 22.1 12.7 9.1e-05 21.8 8.8 1.1 1 0 0 1 1 1 1 PRA1 family protein Glyco_hydro_47 PF01532.15 EEB07907.2 - 5.9e-158 526.2 0.1 6.8e-158 526.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apo-CII PF05355.6 EEB07907.2 - 0.094 12.5 1.4 26 4.7 0.0 3.1 3 0 0 3 3 3 0 Apolipoprotein C-II FhuF PF06276.7 EEB07908.1 - 0.026 14.4 0.2 0.044 13.7 0.1 1.4 1 1 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Ribosomal_S6e PF01092.14 EEB07909.1 - 4.1e-64 213.9 0.2 8.9e-64 212.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e RNA_pol_Rpb4 PF03874.11 EEB07910.1 - 4.8e-21 74.9 4.2 5.9e-21 74.6 2.9 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF3811 PF11656.3 EEB07910.1 - 0.35 10.9 2.5 2.2 8.3 0.1 2.7 3 0 0 3 3 3 0 YjbD family (DUF3811) TIP49 PF06068.8 EEB07911.2 - 1.5e-179 596.8 5.8 1.8e-179 596.5 4.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEB07911.2 - 4e-11 43.2 2.5 2.9e-07 30.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEB07911.2 - 4.3e-07 29.2 3.3 0.0014 17.7 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEB07911.2 - 1.9e-06 28.0 0.3 2.8e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEB07911.2 - 1.2e-05 25.5 0.9 0.14 12.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EEB07911.2 - 0.00015 20.9 0.8 0.0086 15.2 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 EEB07911.2 - 0.00019 20.4 0.1 0.00036 19.5 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.1 EEB07911.2 - 0.00027 20.8 0.8 1.7 8.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EEB07911.2 - 0.0029 17.3 0.1 2.1 8.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEB07911.2 - 0.0032 17.3 0.4 0.074 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EEB07911.2 - 0.0076 15.7 0.1 4.5 6.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EEB07911.2 - 0.01 15.7 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEB07911.2 - 0.012 14.7 0.1 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEB07911.2 - 0.018 15.8 0.2 0.068 13.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EEB07911.2 - 0.037 13.2 0.0 0.083 12.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 EEB07911.2 - 0.044 13.3 0.5 0.63 9.6 0.3 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 EEB07911.2 - 0.059 13.1 0.3 0.24 11.1 0.0 2.2 3 0 0 3 3 3 0 Part of AAA domain UPF0079 PF02367.12 EEB07911.2 - 0.067 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EEB07911.2 - 0.068 12.5 0.5 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Apc15p PF05841.6 EEB07912.1 - 2.7e-10 41.0 0.3 6.9e-10 39.7 0.2 1.7 1 1 0 1 1 1 1 Apc15p protein BUD22 PF09073.5 EEB07912.1 - 4.5 6.2 6.9 5.5 5.9 4.8 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 EEB07912.1 - 5.9 5.4 13.3 8.2 5.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA12 PF10443.4 EEB07913.1 - 1e-119 399.9 0.0 2.3e-119 398.7 0.0 1.6 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EEB07913.1 - 4.3e-08 33.1 0.1 3e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase RRM_1 PF00076.17 EEB07913.1 - 0.00043 19.8 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EEB07913.1 - 0.0028 17.6 0.2 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEB07913.1 - 0.0049 16.7 0.0 0.19 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EEB07913.1 - 0.037 14.1 0.0 0.23 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain Glycos_trans_3N PF02885.12 EEB07913.1 - 0.16 11.5 0.0 28 4.4 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain MFS_1 PF07690.11 EEB07914.1 - 1.9e-19 69.6 33.3 1.1e-18 67.0 23.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L36 PF00444.13 EEB07915.1 - 6.7e-15 54.7 4.6 1.3e-14 53.9 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 DUF3503 PF12011.3 EEB07915.1 - 0.0097 15.6 0.1 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3503) TFIIA PF03153.8 EEB07915.1 - 0.29 10.9 13.3 0.36 10.6 9.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EEB07915.1 - 0.32 9.1 21.2 0.38 8.9 14.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 JmjC PF02373.17 EEB07916.2 - 2.1e-26 92.4 0.1 2.7e-25 88.8 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EEB07916.2 - 8e-05 22.0 0.1 0.00015 21.1 0.1 1.5 1 0 0 1 1 1 1 jmjN domain Ribosomal_L37ae PF01780.14 EEB07918.1 - 2.6e-37 126.5 8.8 2.8e-37 126.4 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEB07918.1 - 0.0018 17.7 3.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Saf-Nte_pilin PF09460.5 EEB07918.1 - 0.012 15.3 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 0 Saf-pilin pilus formation protein zf-H2C2_2 PF13465.1 EEB07918.1 - 0.016 15.5 0.6 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 EEB07918.1 - 0.066 12.4 0.3 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 EEB07918.1 - 0.08 12.6 0.6 0.16 11.6 0.4 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Terminase_GpA PF05876.7 EEB07918.1 - 0.087 11.1 0.4 0.09 11.1 0.3 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 EEB07918.1 - 0.094 12.5 4.2 0.15 11.8 2.9 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EEB07918.1 - 0.14 12.1 1.5 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.1 EEB07918.1 - 0.19 12.0 1.4 0.34 11.2 1.0 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Sgf11 PF08209.6 EEB07918.1 - 0.19 11.0 1.6 5.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DNA_ligase_ZBD PF03119.11 EEB07918.1 - 0.23 11.1 0.9 0.47 10.2 0.6 1.5 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Sec23_Sec24 PF04810.10 EEB07918.1 - 0.31 10.6 0.1 0.31 10.6 0.1 1.9 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC5 PF06221.8 EEB07918.1 - 0.96 9.2 3.7 2.4 7.9 0.2 2.2 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2 PF00096.21 EEB07918.1 - 5.9 7.4 6.2 1.5 9.3 0.2 2.4 3 0 0 3 3 2 0 Zinc finger, C2H2 type EF-hand_4 PF12763.2 EEB07919.1 - 1.8e-26 91.9 0.1 2.6e-10 39.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EEB07919.1 - 9.5e-11 41.2 0.3 2.2e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EEB07919.1 - 1.4e-08 33.4 0.1 0.051 12.8 0.0 4.4 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 EEB07919.1 - 5.4e-08 32.8 0.1 0.088 12.9 0.1 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EEB07919.1 - 1.9e-07 30.6 0.4 0.045 13.3 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EEB07919.1 - 1.8e-06 27.3 0.9 1.2 9.2 0.1 4.5 4 0 0 4 4 4 2 EF-hand domain ERM PF00769.14 EEB07919.1 - 0.00016 21.3 14.5 0.00016 21.3 10.0 1.9 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Laminin_I PF06008.9 EEB07919.1 - 0.00022 20.6 5.4 0.00042 19.7 3.8 1.4 1 0 0 1 1 1 1 Laminin Domain I CUE PF02845.11 EEB07919.1 - 0.003 16.9 0.3 0.0076 15.7 0.2 1.7 1 0 0 1 1 1 1 CUE domain HAP1_N PF04849.8 EEB07919.1 - 0.0063 15.4 7.7 0.012 14.5 5.3 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF1635 PF07795.6 EEB07919.1 - 0.008 15.5 2.0 0.008 15.5 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) GAS PF13851.1 EEB07919.1 - 0.0096 15.1 9.0 0.019 14.1 6.2 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EEB07919.1 - 0.016 14.9 11.4 0.045 13.4 7.9 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HOOK PF05622.7 EEB07919.1 - 0.031 12.1 8.7 0.046 11.5 6.0 1.1 1 0 0 1 1 1 0 HOOK protein DUF342 PF03961.8 EEB07919.1 - 0.049 12.0 2.5 0.076 11.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EEB07919.1 - 0.081 10.7 6.5 0.11 10.2 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EEB07919.1 - 0.092 12.5 8.2 0.21 11.4 5.7 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EEB07919.1 - 0.15 11.1 14.2 0.27 10.2 9.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 EEB07919.1 - 0.47 8.8 12.5 0.87 8.0 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.17 EEB07919.1 - 0.78 9.7 9.7 0.58 10.1 4.8 2.2 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 EEB07919.1 - 1.3 7.6 10.9 2.2 6.8 7.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.1 EEB07919.1 - 1.5 8.8 13.3 8 6.4 9.2 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 EEB07919.1 - 2.1 7.9 10.7 6.6 6.3 1.5 2.8 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.13 EEB07919.1 - 2.6 7.8 9.5 4.3 7.1 0.9 3.0 1 1 2 3 3 3 0 Homeobox associated leucine zipper FUSC PF04632.7 EEB07919.1 - 3.2 6.0 7.7 5.4 5.3 5.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FtsL PF04999.8 EEB07919.1 - 5.6 6.7 11.4 0.95 9.2 5.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsL IncA PF04156.9 EEB07919.1 - 8 6.0 16.7 3.5 7.1 8.0 2.3 1 1 1 2 2 2 0 IncA protein NatB_MDM20 PF09797.4 EEB07920.1 - 6.5e-66 222.5 10.0 1e-65 221.8 6.9 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 EEB07920.1 - 0.0068 17.0 0.0 10 6.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB07920.1 - 0.037 14.3 1.8 3.5 8.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat GYR PF02756.9 EEB07920.1 - 2.3 8.1 4.8 4.9 7.0 3.3 1.5 1 0 0 1 1 1 0 GYR motif SURF1 PF02104.10 EEB07921.1 - 3.3e-55 187.2 0.1 4e-55 186.9 0.1 1.1 1 0 0 1 1 1 1 SURF1 family 60KD_IMP PF02096.15 EEB07921.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Histone PF00125.19 EEB07922.1 - 4.9e-22 77.8 0.1 6.1e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB07922.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 EEB07923.1 - 5.7e-75 251.8 0.0 6.5e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07923.1 - 1.4e-30 106.2 0.0 1.7e-30 105.9 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07923.1 - 1.1e-06 27.7 0.0 8.3e-06 24.9 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEB07923.1 - 0.0026 16.6 0.0 0.0056 15.5 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 EEB07923.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF106 PF01956.11 EEB07924.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 WW PF00397.21 EEB07924.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.0 3 0 0 3 3 3 0 WW domain CDC50 PF03381.10 EEB07925.1 - 1.8e-92 309.4 0.2 2.1e-92 309.2 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family F-112 PF09645.5 EEB07926.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 F-112 protein Pilin PF00114.14 EEB07926.1 - 0.14 12.8 0.6 0.23 12.2 0.4 1.6 1 1 0 1 1 1 0 Pilin (bacterial filament) DnaJ PF00226.26 EEB07927.1 - 3.4e-20 71.5 1.0 1.1e-19 69.9 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain CotJB PF12652.2 EEB07927.1 - 0.05 13.6 2.0 0.15 12.1 0.1 2.7 3 0 0 3 3 3 0 CotJB protein Ribosomal_S15 PF00312.17 EEB07928.1 - 7.6e-20 70.4 0.9 7.6e-20 70.4 0.6 2.5 3 0 0 3 3 3 1 Ribosomal protein S15 Dor1 PF04124.7 EEB07929.1 - 3.2e-35 121.2 15.9 5.1e-35 120.5 11.0 1.3 1 0 0 1 1 1 1 Dor1-like family MutS_III PF05192.13 EEB07929.1 - 0.017 14.8 4.4 0.025 14.3 2.5 1.6 1 1 0 1 1 1 0 MutS domain III Aminotran_1_2 PF00155.16 EEB07930.2 - 5.1e-65 219.7 0.0 6.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEB07930.2 - 0.0043 15.4 0.0 0.014 13.6 0.0 1.8 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glycos_transf_1 PF00534.15 EEB07931.1 - 7.9e-26 90.5 0.0 3.7e-24 85.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEB07931.1 - 3.1e-07 30.2 0.0 9e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEB07931.1 - 0.00011 22.2 0.0 0.00028 21.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEB07931.1 - 0.00034 20.7 0.0 0.00098 19.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEB07931.1 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EEB07932.1 - 2.4e-17 63.3 0.2 2.4e-17 63.3 0.1 4.1 4 1 0 4 4 4 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEB07932.1 - 1.7e-13 50.6 0.0 3.1e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB07932.1 - 4.7e-11 42.4 0.0 1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Actin PF00022.14 EEB07933.1 - 2.6e-29 101.8 0.0 3e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Actin Fork_head PF00250.13 EEB07934.1 - 3.4e-33 113.5 0.1 6e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Fork head domain COX_ARM PF06481.9 EEB07934.1 - 0.041 13.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 COX Aromatic Rich Motif Pkinase PF00069.20 EEB07935.1 - 8.6e-72 241.4 0.0 1.1e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07935.1 - 1.3e-35 122.6 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB07935.1 - 0.0015 17.5 0.0 0.0031 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEB07935.1 - 0.025 14.3 0.6 0.09 12.4 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family eIF2A PF08662.6 EEB07936.1 - 2.5e-05 24.0 0.3 0.0031 17.2 0.0 3.3 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF2139 PF09910.4 EEB07936.1 - 0.038 13.0 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2139) Vps16_N PF04841.8 EEB07936.1 - 0.046 12.2 0.2 0.12 10.8 0.0 1.7 2 0 0 2 2 2 0 Vps16, N-terminal region DLH PF01738.13 EEB07937.1 - 1.8e-18 66.6 0.0 2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEB07937.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Transket_pyr PF02779.19 EEB07938.1 - 2e-42 144.6 0.0 3.3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEB07938.1 - 5.3e-36 123.2 0.1 1.2e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain MRP-S33 PF08293.6 EEB07939.2 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.2 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.10 EEB07940.2 - 5.6e-66 221.8 13.3 1.3e-65 220.6 9.2 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3043 PF11241.3 EEB07940.2 - 1.3 8.5 5.6 1.3 8.6 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) FAT PF02259.18 EEB07941.2 - 1.9e-94 316.5 7.9 3.9e-94 315.5 0.7 2.4 2 0 0 2 2 2 2 FAT domain PI3_PI4_kinase PF00454.22 EEB07941.2 - 2.5e-55 187.5 0.3 4.4e-55 186.7 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EEB07941.2 - 4.1e-45 153.5 4.3 2.3e-44 151.1 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EEB07941.2 - 3.9e-37 126.3 0.9 3.9e-37 126.3 0.7 3.3 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EEB07941.2 - 3.6e-21 75.2 8.1 0.00038 20.6 0.1 8.8 5 1 3 8 8 8 4 HEAT repeats FATC PF02260.15 EEB07941.2 - 4.6e-16 57.9 0.2 9.8e-16 56.8 0.2 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EEB07941.2 - 1.2e-11 43.6 14.7 0.0023 17.8 0.0 10.5 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EEB07941.2 - 2.8e-09 37.1 21.1 0.016 15.7 0.1 9.2 8 1 2 10 10 10 3 HEAT-like repeat YvbH_ext PF11724.3 EEB07941.2 - 0.0026 17.3 0.0 0.012 15.2 0.0 2.1 1 0 0 1 1 1 1 YvbH-like oligomerisation region TB2_DP1_HVA22 PF03134.14 EEB07942.1 - 6.7e-22 77.0 2.5 1.2e-20 72.9 1.7 2.1 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.7 EEB07943.1 - 2.9e-92 306.6 0.0 3.8e-92 306.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 EEB07944.1 - 8.7e-100 334.0 0.0 1.2e-99 333.6 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EEB07944.1 - 3.4e-19 69.0 0.0 5.7e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EEB07944.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain GATase_3 PF07685.9 EEB07944.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain LSM PF01423.17 EEB07945.1 - 1.6e-17 62.8 0.0 2.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB07945.1 - 0.043 13.7 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Granin PF01271.12 EEB07945.1 - 0.07 11.8 0.3 0.072 11.7 0.2 1.0 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) API5 PF05918.6 EEB07945.1 - 1.3 7.4 6.3 1.6 7.1 4.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) tRNA-synt_1c PF00749.16 EEB07946.1 - 2.5e-94 315.4 0.0 3.1e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Ras PF00071.17 EEB07947.2 - 1.7e-53 180.3 0.0 2e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB07947.2 - 1.6e-21 76.9 0.0 2.4e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB07947.2 - 4.3e-13 48.8 0.0 5.2e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEB07947.2 - 2.1e-07 30.9 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEB07947.2 - 1.2e-06 27.8 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EEB07947.2 - 9.2e-06 25.3 0.0 0.018 14.6 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEB07947.2 - 1.9e-05 24.1 0.0 0.00028 20.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEB07947.2 - 0.00078 18.6 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEB07947.2 - 0.00092 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EEB07947.2 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB07947.2 - 0.0018 18.4 0.0 0.0042 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EEB07947.2 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEB07947.2 - 0.0024 17.3 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MobB PF03205.9 EEB07947.2 - 0.004 16.8 0.0 0.0068 16.1 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEB07947.2 - 0.0045 16.4 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EEB07947.2 - 0.009 15.0 0.1 0.021 13.8 0.0 1.6 2 0 0 2 2 2 1 Septin NACHT PF05729.7 EEB07947.2 - 0.019 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EEB07947.2 - 0.039 13.1 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EEB07947.2 - 0.04 14.2 0.1 0.047 13.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EEB07947.2 - 0.044 13.5 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 EEB07947.2 - 0.046 13.2 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EEB07947.2 - 0.049 13.5 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEB07947.2 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEB07947.2 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EEB07947.2 - 0.09 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EEB07947.2 - 0.094 12.8 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 1 0 RNA helicase MAP65_ASE1 PF03999.7 EEB07948.1 - 9.6e-102 341.5 26.3 1.2e-101 341.2 18.2 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Herpes_BTRF1 PF04682.7 EEB07948.1 - 0.36 10.1 3.8 0.32 10.2 0.1 2.4 3 0 0 3 3 3 0 Herpesvirus BTRF1 protein conserved region TBPIP PF07106.8 EEB07948.1 - 3.6 7.0 14.8 0.1 12.1 0.9 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Serinc PF03348.10 EEB07950.1 - 1e-127 426.4 22.0 1.3e-127 426.1 15.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) EST1_DNA_bind PF10373.4 EEB07950.1 - 0.0038 16.4 3.4 0.087 12.0 2.4 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain HA2 PF04408.18 EEB07951.1 - 4.3e-20 71.6 0.0 4.3e-20 71.6 0.0 2.7 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEB07951.1 - 4.2e-14 52.1 0.0 1.6e-13 50.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEB07951.1 - 4.1e-09 36.2 0.2 2.9e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEB07951.1 - 1.1e-05 25.0 0.8 5.9e-05 22.6 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB07951.1 - 0.00037 20.6 0.7 0.0042 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Hormone_recep PF00104.25 EEB07951.1 - 0.0014 17.7 0.0 0.0035 16.5 0.0 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor AAA_33 PF13671.1 EEB07951.1 - 0.026 14.4 0.7 0.097 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain INO80_Ies4 PF08193.6 EEB07952.2 - 0.36 10.7 5.1 1 9.2 0.4 2.3 2 0 0 2 2 2 0 INO80 complex subunit Ies4 MFS_1 PF07690.11 EEB07953.1 - 2.9e-45 154.5 34.6 2.9e-45 154.5 24.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3817 PF12823.2 EEB07953.1 - 2.8 8.4 16.4 0.19 12.2 0.6 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF3817) DUF2423 PF10338.4 EEB07954.1 - 4.3e-18 65.0 0.5 4.3e-18 65.0 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Mrr_N PF14338.1 EEB07954.1 - 0.029 14.4 0.3 0.054 13.5 0.1 1.5 1 1 0 1 1 1 0 Mrr N-terminal domain HK97-gp10_like PF04883.7 EEB07954.1 - 0.38 11.7 4.7 1.5 9.7 2.0 2.3 1 1 2 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component WD40 PF00400.27 EEB07955.1 - 1.8e-40 135.3 18.1 6.1e-10 38.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EEB07955.1 - 1.1e-05 23.8 2.1 0.027 12.6 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EEB07955.1 - 0.00092 18.9 0.1 7.4 6.2 0.0 3.3 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Glyco_transf_15 PF01793.11 EEB07956.1 - 8.7e-123 409.4 16.1 1.1e-122 409.1 11.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase 4HBT_2 PF13279.1 EEB07956.1 - 0.069 13.5 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Thioesterase-like superfamily Pkinase PF00069.20 EEB07957.2 - 2.3e-39 135.1 0.1 7.1e-38 130.2 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB07957.2 - 2e-17 63.1 0.0 3.9e-15 55.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EEB07957.2 - 5.6e-05 22.9 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 PH domain RabGAP-TBC PF00566.13 EEB07958.1 - 3.1e-35 121.5 0.1 4.5e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RVT_3 PF13456.1 EEB07958.1 - 0.1 12.4 0.3 2.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Reverse transcriptase-like P21-Arc PF04062.9 EEB07959.1 - 8.3e-79 263.4 0.0 9.2e-79 263.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit N2227 PF07942.7 EEB07960.2 - 3.6e-104 347.5 0.0 4.2e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EEB07960.2 - 0.00013 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB07960.2 - 0.073 13.6 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEB07960.2 - 0.083 13.3 0.0 0.62 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEB07960.2 - 0.086 12.4 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain CH PF00307.26 EEB07961.1 - 1.8e-67 224.1 0.1 2.4e-19 69.3 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.27 EEB07961.1 - 1.6e-05 23.8 0.1 1.2 8.5 0.0 3.7 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 EEB07961.1 - 7.3e-05 22.3 0.0 4.8 6.9 0.0 4.0 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 EEB07961.1 - 0.00094 19.2 0.2 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEB07961.1 - 0.0018 18.0 0.1 1.3 9.0 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EEB07961.1 - 0.0097 15.5 0.0 1.3 8.6 0.0 3.0 1 1 1 2 2 2 1 EF-hand domain pair Dfp1_Him1_M PF08630.5 EEB07963.1 - 2.1e-23 82.4 0.0 4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EEB07963.1 - 5.9e-17 61.0 1.5 1.5e-16 59.8 1.0 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EEB07963.1 - 0.0047 17.0 0.1 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB07963.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BAF1_ABF1 PF04684.8 EEB07963.1 - 0.045 12.6 2.2 0.071 11.9 1.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 EEB07963.1 - 0.41 11.0 10.4 1 9.7 7.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUDIX PF00293.23 EEB07964.1 - 2.4e-13 49.9 0.0 6.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EEB07964.1 - 2.2e-09 37.5 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EEB07964.1 - 0.00028 20.3 1.4 0.002 17.5 0.4 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Myb_DNA-bind_2 PF08914.6 EEB07965.2 - 6.9e-11 41.7 0.2 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EEB07965.2 - 4.3e-05 24.0 0.1 0.00013 22.5 0.0 1.8 1 0 0 1 1 1 1 Rap1, DNA-binding TFIIE_alpha PF02002.12 EEB07965.2 - 0.12 11.8 0.1 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit BTB PF00651.26 EEB07966.2 - 3.6e-07 30.1 0.1 6.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DnaJ PF00226.26 EEB07967.1 - 1.4e-20 72.8 3.8 4.3e-20 71.1 2.7 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3987 PF13148.1 EEB07967.1 - 0.0013 17.3 9.8 0.0013 17.3 6.8 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) Presenilin PF01080.12 EEB07967.1 - 4.9 5.8 6.6 9 4.9 4.6 1.3 1 0 0 1 1 1 0 Presenilin CBFD_NFYB_HMF PF00808.18 EEB07968.1 - 9.2e-20 70.4 0.9 9.2e-20 70.4 0.6 2.2 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB07968.1 - 0.00043 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ish1 PF10281.4 EEB07968.1 - 0.18 11.9 2.7 20 5.3 0.0 3.6 2 1 1 3 3 3 0 Putative stress-responsive nuclear envelope protein ISN1 PF06437.6 EEB07969.1 - 4.3e-160 532.8 0.0 4.9e-160 532.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Swi3 PF07962.7 EEB07970.2 - 5.9e-30 102.7 0.4 8.4e-30 102.2 0.3 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 adh_short PF00106.20 EEB07971.1 - 2.8e-28 98.9 1.0 3.8e-28 98.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB07971.1 - 2.4e-14 53.7 0.1 3.2e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB07971.1 - 3e-10 40.0 1.0 4.6e-10 39.4 0.7 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEB07971.1 - 0.02 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Complex1_LYR PF05347.10 EEB07972.1 - 2e-06 27.5 0.3 2.6e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEB07972.1 - 0.00033 20.8 0.3 0.00043 20.4 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF4132 PF13569.1 EEB07972.1 - 0.03 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF924 PF06041.6 EEB07972.1 - 0.055 13.2 0.1 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) DUF3106 PF11304.3 EEB07972.1 - 0.11 12.9 0.5 0.16 12.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Exonuc_VII_S PF02609.11 EEB07972.1 - 0.11 12.2 0.2 4.4 7.1 0.0 2.3 2 1 0 2 2 2 0 Exonuclease VII small subunit 5_3_exonuc_N PF02739.11 EEB07972.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol3_delt_C PF14840.1 EEB07972.1 - 0.15 12.2 0.2 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term APG9 PF04109.11 EEB07973.1 - 3.8e-143 476.8 5.0 5.4e-143 476.3 3.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_fiss_reg PF05308.6 EEB07974.1 - 0.0041 16.5 0.4 0.0054 16.1 0.3 1.3 1 1 0 1 1 1 1 Mitochondrial fission regulator TMF_DNA_bd PF12329.3 EEB07974.1 - 0.09 12.5 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cys_Met_Meta_PP PF01053.15 EEB07975.1 - 6.7e-40 136.5 0.0 8.8e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEB07975.1 - 0.0035 16.3 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Nucleoporin_FG PF13634.1 EEB07976.1 - 0.002 18.3 163.4 0.13 12.5 43.2 4.9 1 1 2 3 3 3 2 Nucleoporin FG repeat region MAM33 PF02330.11 EEB07977.1 - 0.00042 20.1 3.2 0.00095 18.9 2.2 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein AKAP7_NLS PF10469.4 EEB07979.1 - 2.2e-25 89.5 0.0 2.6e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain WD40 PF00400.27 EEB07980.1 - 3.3e-46 153.5 11.8 2.2e-09 36.8 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEB07980.1 - 1.2e-45 155.0 0.6 3.1e-45 153.7 0.4 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EEB07980.1 - 0.0004 20.0 0.0 0.0013 18.3 0.0 2.0 1 0 0 1 1 1 1 LisH Hydrolase_6 PF13344.1 EEB07981.1 - 1.7e-30 104.9 0.0 2.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB07981.1 - 6.6e-13 48.1 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEB07981.1 - 2.3e-11 44.5 0.0 5.7e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEB07981.1 - 2.7e-05 24.4 0.0 0.08 13.1 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EEB07981.1 - 0.13 11.6 0.0 0.7 9.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Cep57_CLD_2 PF14197.1 EEB07982.1 - 0.018 15.0 2.5 2.4 8.1 0.4 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 UBN_AB PF14075.1 EEB07982.1 - 0.056 13.1 0.3 0.081 12.5 0.2 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Acetyltransf_1 PF00583.19 EEB07985.1 - 3.2e-16 59.1 0.2 5.9e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEB07985.1 - 2.6e-10 40.4 0.0 4.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EEB07985.1 - 2.7e-09 36.4 2.6 5.9e-09 35.3 1.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acetyltransf_7 PF13508.1 EEB07985.1 - 2.7e-08 33.8 0.2 6.4e-08 32.6 0.0 1.7 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 EEB07985.1 - 2.9e-07 30.3 12.3 6.6e-07 29.2 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB07985.1 - 4.2e-06 26.3 7.4 9.2e-06 25.2 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_4 PF13420.1 EEB07985.1 - 5e-05 23.2 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3HC4 PF00097.20 EEB07985.1 - 0.00021 20.8 13.4 0.00051 19.6 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB07985.1 - 0.00031 20.4 11.5 0.00065 19.3 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEB07985.1 - 0.00033 20.4 9.8 0.0008 19.1 6.8 1.7 1 0 0 1 1 1 1 Ring finger domain FR47 PF08445.5 EEB07985.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein zf-C3HC4_4 PF15227.1 EEB07985.1 - 0.64 9.9 10.0 1.5 8.7 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEB07985.1 - 1.1 9.0 7.7 3.5 7.4 5.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 EEB07985.1 - 1.6 8.2 7.7 4.3 6.9 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.12 EEB07986.2 - 5.3e-13 48.6 0.2 9.7e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEB07986.2 - 1.2e-09 38.1 0.1 1.9e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EEB07986.2 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 IGR protein motif ATP-synt_DE_N PF02823.11 EEB07987.1 - 1.5e-16 59.8 0.0 2.4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Mannosyl_trans PF05007.8 EEB07988.1 - 5.6e-79 265.4 23.6 5.6e-79 265.4 16.4 2.1 3 0 0 3 3 3 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EEB07988.1 - 3.4e-08 32.7 22.0 3.4e-08 32.7 15.3 3.0 2 2 0 2 2 2 1 GPI transamidase subunit PIG-U ADIP PF11559.3 EEB07989.1 - 1.4e-18 67.2 17.4 1.4e-18 67.2 12.1 3.2 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding ERM PF00769.14 EEB07989.1 - 0.046 13.2 29.0 0.06 12.8 14.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family NYD-SP28_assoc PF14775.1 EEB07989.1 - 2.6 7.7 12.7 2.5 7.8 1.0 3.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF2500 PF10694.4 EEB07990.2 - 0.024 14.6 0.8 0.024 14.6 0.6 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2500) Leo1 PF04004.8 EEB07991.2 - 6.4e-39 133.4 0.8 6.4e-39 133.4 0.6 2.5 2 1 1 3 3 3 1 Leo1-like protein WH2 PF02205.15 EEB07992.1 - 1.6e-11 43.3 1.3 4.6e-11 41.9 0.5 2.0 2 0 0 2 2 2 1 WH2 motif TFIIB PF00382.14 EEB07993.1 - 2.5e-34 116.9 4.3 7.1e-18 64.1 0.1 3.1 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EEB07993.1 - 8.8e-28 96.3 4.2 8.8e-28 96.3 2.9 2.6 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EEB07993.1 - 1.3e-08 34.0 3.0 3.2e-08 32.7 2.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EEB07993.1 - 5.1e-06 26.0 0.2 0.1 12.1 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 EEB07993.1 - 0.075 12.2 1.0 0.17 11.1 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain RRN7 PF11781.3 EEB07993.1 - 0.73 9.3 7.3 0.19 11.2 2.3 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Lar_restr_allev PF14354.1 EEB07993.1 - 1.1 9.5 3.9 0.9 9.8 1.2 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF3573 PF12097.3 EEB07993.1 - 1.2 7.6 5.2 2 6.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Rhomboid PF01694.17 EEB07994.1 - 1e-20 74.2 14.4 1.5e-20 73.7 8.8 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1122 PF06557.6 EEB07994.1 - 0.13 11.4 0.5 0.47 9.5 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Ribosomal_L1 PF00687.16 EEB07995.1 - 8.4e-52 175.6 1.5 9.8e-52 175.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SMI1_KNR4 PF09346.5 EEB07996.1 - 1.5e-31 109.0 0.0 2.4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PDT PF00800.13 EEB07997.1 - 1.3e-57 194.3 0.0 1.7e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Gar1 PF04410.9 EEB07998.1 - 4.9e-44 149.5 0.1 1.1e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SR-25 PF10500.4 EEB07998.1 - 0.05 13.0 8.1 0.1 12.0 1.0 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.7 EEB07998.1 - 0.33 9.2 18.4 0.25 9.6 6.4 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tom37_C PF11801.3 EEB07998.1 - 0.52 10.1 6.5 6.9 6.5 0.6 2.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Metallophos PF00149.23 EEB07999.2 - 5.9e-44 149.8 0.5 7.1e-44 149.5 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L29e PF01779.12 EEB08000.1 - 8.8e-22 76.6 14.8 1.2e-21 76.3 10.2 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family SSrecog PF03531.9 EEB08001.1 - 2.1e-95 318.2 0.1 3.5e-95 317.5 0.1 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EEB08001.1 - 4.1e-29 100.4 0.4 1.6e-27 95.2 0.0 2.5 2 1 0 2 2 2 1 Histone chaperone Rttp106-like Pkinase PF00069.20 EEB08002.1 - 0.0078 15.3 0.2 0.29 10.2 0.1 2.5 1 1 0 1 1 1 1 Protein kinase domain Tachylectin PF14517.1 EEB08002.1 - 0.071 12.4 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Tachylectin WD40 PF00400.27 EEB08003.2 - 8.2e-27 92.0 16.9 5.4e-07 29.2 0.2 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3590 PF12148.3 EEB08003.2 - 0.066 12.8 0.8 0.19 11.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3590) TFIIA PF03153.8 EEB08003.2 - 0.077 12.8 4.6 0.11 12.3 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4611 PF15387.1 EEB08003.2 - 1.6 8.9 6.4 3.6 7.7 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DSPc PF00782.15 EEB08004.1 - 5.9e-09 35.6 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEB08004.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEB08004.1 - 0.00022 21.4 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEB08004.1 - 0.00032 20.7 0.0 0.00096 19.2 0.0 1.7 1 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EEB08004.1 - 0.016 14.5 0.0 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family RNB PF00773.14 EEB08005.2 - 1.9e-44 152.2 0.3 4.5e-44 151.0 0.2 1.7 1 0 0 1 1 1 1 RNB domain Ribosomal_L36e PF01158.13 EEB08006.1 - 5.9e-40 135.2 2.7 6.4e-40 135.1 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.1 EEB08006.1 - 0.017 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal DnaJ PF00226.26 EEB08008.1 - 8.6e-21 73.4 1.0 1.5e-20 72.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEB08008.1 - 8.6e-19 67.2 0.0 3.2e-16 58.9 0.0 3.6 3 1 1 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEB08008.1 - 7.3e-13 48.3 18.6 1.2e-12 47.6 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.2 EEB08008.1 - 0.34 10.7 6.3 4.5 7.1 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 EEB08008.1 - 0.42 10.7 2.3 0.76 9.9 0.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Antiterm PF03589.8 EEB08008.1 - 1.7 8.7 8.0 2.4 8.3 1.1 2.6 1 1 1 2 2 2 0 Antitermination protein ATG16 PF08614.6 EEB08009.1 - 3e-09 36.9 13.5 2.1e-07 30.9 9.4 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) CaMBD PF02888.11 EEB08009.1 - 0.0042 16.8 1.6 0.0093 15.7 1.1 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Rep_4 PF05797.6 EEB08009.1 - 0.017 13.8 2.1 0.021 13.5 1.4 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) IncA PF04156.9 EEB08009.1 - 0.03 13.8 6.9 0.043 13.4 4.8 1.3 1 0 0 1 1 1 0 IncA protein DUF2772 PF10970.3 EEB08009.1 - 0.033 14.2 1.6 0.25 11.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2772) DUF2951 PF11166.3 EEB08009.1 - 0.12 12.2 3.5 0.2 11.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) SlyX PF04102.7 EEB08009.1 - 0.26 11.6 14.0 1.3 9.4 3.4 2.4 1 1 1 2 2 2 0 SlyX FlxA PF14282.1 EEB08009.1 - 0.31 11.0 17.6 1.5 8.7 7.2 2.2 1 1 1 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.4 EEB08009.1 - 0.32 11.1 6.1 2.7 8.1 1.8 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 EEB08009.1 - 0.6 10.5 9.1 4 7.9 1.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 EEB08009.1 - 0.64 9.8 5.5 0.99 9.2 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 EEB08009.1 - 5.5 6.3 13.9 22 4.3 9.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Ras PF00071.17 EEB08010.1 - 1.5e-57 193.5 0.1 1.7e-57 193.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB08010.1 - 4.8e-19 69.0 0.0 7.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB08010.1 - 6.5e-12 45.0 0.0 8.7e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB08010.1 - 2.3e-08 33.4 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEB08010.1 - 8e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEB08010.1 - 4.7e-07 29.4 0.0 7.9e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EEB08010.1 - 2.1e-05 24.2 0.4 0.0025 17.4 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EEB08010.1 - 0.00028 20.6 0.3 0.00067 19.4 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EEB08010.1 - 0.00058 20.0 0.0 0.0015 18.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EEB08010.1 - 0.00065 18.9 0.1 0.0012 18.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EEB08010.1 - 0.0014 17.7 0.2 0.0047 15.9 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_16 PF13191.1 EEB08010.1 - 0.0019 18.2 0.1 0.0035 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 EEB08010.1 - 0.0026 17.2 0.1 0.014 14.8 0.0 1.9 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EEB08010.1 - 0.0036 16.9 0.2 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEB08010.1 - 0.0046 16.4 0.1 0.0095 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EEB08010.1 - 0.0047 16.5 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EEB08010.1 - 0.006 16.0 0.1 0.073 12.5 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EEB08010.1 - 0.0067 15.6 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EEB08010.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EEB08010.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EEB08010.1 - 0.026 14.7 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EEB08010.1 - 0.039 14.2 0.2 0.048 13.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EEB08010.1 - 0.05 12.2 1.6 0.75 8.4 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit PseudoU_synth_2 PF00849.17 EEB08010.1 - 0.05 13.4 0.0 0.056 13.2 0.0 1.3 1 1 0 1 1 1 0 RNA pseudouridylate synthase AAA_5 PF07728.9 EEB08010.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EEB08010.1 - 0.069 12.4 0.1 1.2 8.3 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EEB08010.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEB08010.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain EamA PF00892.15 EEB08011.1 - 1.2e-07 31.7 28.9 4.4e-05 23.5 2.4 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EEB08011.1 - 9.1e-07 28.0 14.8 9.1e-07 28.0 10.2 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EEB08011.1 - 1.9e-05 24.7 21.6 0.0031 17.6 0.7 3.4 3 0 0 3 3 3 3 Multidrug resistance efflux transporter UAA PF08449.6 EEB08011.1 - 0.00062 18.7 13.8 0.0011 17.9 9.5 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEB08011.1 - 0.0067 16.0 27.9 0.038 13.6 6.3 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family GARS_A PF01071.14 EEB08013.2 - 1.1e-80 269.7 0.0 1.7e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EEB08013.2 - 9e-36 122.3 0.1 4.9e-35 119.9 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EEB08013.2 - 1.2e-34 119.5 0.0 3.3e-34 118.1 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EEB08013.2 - 1.6e-29 101.9 0.1 4.1e-29 100.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EEB08013.2 - 6.5e-18 64.7 0.3 3e-17 62.6 0.2 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EEB08013.2 - 2.6e-08 33.8 0.0 1.4e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEB08013.2 - 3.6e-06 25.9 0.0 8.1e-06 24.8 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EEB08013.2 - 0.0087 15.9 0.1 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GHMP_kinases_N PF00288.21 EEB08014.1 - 1.2e-12 47.7 0.1 3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEB08014.1 - 7e-06 26.1 0.1 2.1e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Mss4 PF04421.8 EEB08015.1 - 8.8e-19 67.1 0.0 2e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Mss4 protein zf-RING_3 PF14369.1 EEB08015.1 - 0.12 12.3 0.6 10 6.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger Fork_head PF00250.13 EEB08016.1 - 2.1e-31 107.8 0.0 4.1e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Fork head domain RNA_pol_Rpb1_5 PF04998.12 EEB08017.1 - 1.3e-98 329.6 0.0 3.1e-98 328.4 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEB08017.1 - 1.1e-62 210.8 0.1 3e-62 209.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEB08017.1 - 9.1e-36 122.9 0.0 2.4e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EEB08017.1 - 3e-30 105.6 9.0 1.5e-24 86.9 0.0 4.3 3 2 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EEB08017.1 - 9.5e-23 80.0 0.1 3.4e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HupH_C PF04809.8 EEB08017.1 - 0.085 12.6 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Actin PF00022.14 EEB08018.1 - 9.6e-159 528.0 0.0 1.1e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEB08018.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FCH PF00611.18 EEB08019.1 - 6.7e-11 42.2 0.4 6.7e-11 42.2 0.3 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain JAB PF01398.16 EEB08020.1 - 4.4e-18 65.0 0.0 8.4e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEB08020.1 - 3.2e-16 59.4 0.0 5.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Hanta_G1 PF01567.11 EEB08021.1 - 0.014 13.7 0.5 0.017 13.4 0.4 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Glyco_transf_8 PF01501.15 EEB08022.1 - 6.5e-11 42.0 0.7 3.4e-10 39.6 0.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.15 EEB08023.1 - 1.2e-11 44.4 0.4 7.7e-11 41.8 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EEB08023.1 - 0.12 11.7 0.8 0.6 9.4 0.6 2.0 1 1 0 1 1 1 0 Mannosyltransferase putative HisG_C PF08029.6 EEB08023.1 - 0.14 12.1 0.1 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain Proteasome PF00227.21 EEB08024.1 - 1.8e-48 164.3 0.7 2e-48 164.2 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Homoserine_dh PF00742.14 EEB08025.2 - 3.5e-51 173.4 0.0 5e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EEB08025.2 - 1.2e-16 61.1 0.0 1.1e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEB08025.2 - 0.03 13.4 0.0 0.079 12.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sec23_trunk PF04811.10 EEB08026.1 - 3e-69 233.0 0.1 4.6e-69 232.4 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEB08026.1 - 9.1e-32 108.5 0.5 2.6e-31 107.1 0.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEB08026.1 - 3.1e-30 104.5 0.9 6.2e-30 103.5 0.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEB08026.1 - 1.3e-15 56.6 5.6 2.9e-15 55.5 3.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEB08026.1 - 5e-15 54.9 0.0 1.5e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat DUF2838 PF10998.3 EEB08027.1 - 1.8e-38 130.8 8.7 1.8e-38 130.8 6.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Bacillus_HBL PF05791.6 EEB08027.1 - 0.13 11.5 1.0 0.29 10.4 0.2 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AKNA PF12443.3 EEB08027.1 - 1.5 8.9 3.3 2.5 8.1 0.7 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor MAM33 PF02330.11 EEB08028.1 - 6.3e-36 124.0 11.6 7.7e-36 123.7 8.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Nrap PF03813.9 EEB08029.1 - 4.5e-274 911.6 0.0 5.5e-274 911.3 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DEAD PF00270.24 EEB08030.1 - 9.1e-40 135.9 0.0 1.3e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08030.1 - 1.8e-23 82.1 0.1 3.3e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EEB08030.1 - 0.038 13.0 0.1 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EEB08030.1 - 0.12 12.1 0.4 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain COG6 PF06419.6 EEB08031.1 - 3.3e-113 378.9 25.6 4e-113 378.6 17.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF234 PF03008.9 EEB08031.1 - 0.00052 20.1 2.6 0.11 12.6 0.1 2.9 3 0 0 3 3 3 2 Archaea bacterial proteins of unknown function DUF885 PF05960.6 EEB08031.1 - 0.061 12.4 2.0 0.1 11.7 1.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ACCA PF03255.9 EEB08031.1 - 2.2 7.8 5.2 0.39 10.2 0.3 2.2 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ribosomal_L18e PF00828.14 EEB08032.1 - 1.2e-32 112.9 0.1 1.5e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EEB08033.1 - 8.2e-44 149.6 0.1 7.5e-42 143.2 0.0 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08033.1 - 2.3e-14 53.1 0.0 6.4e-09 35.2 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EEB08033.1 - 4.5e-06 26.5 1.3 0.0031 17.3 0.0 2.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB08033.1 - 0.07 12.0 0.0 9.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EEB08033.1 - 0.09 11.8 0.4 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1 PF12717.2 EEB08034.1 - 1.2e-49 168.5 10.8 5.8e-48 163.0 1.8 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EEB08034.1 - 7.6e-38 129.8 0.2 2.2e-37 128.3 0.2 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EEB08034.1 - 3.2e-06 27.3 1.1 0.024 14.9 0.0 5.0 3 3 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EEB08034.1 - 7.2e-05 22.5 3.4 7.6 6.8 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EEB08034.1 - 0.0057 17.1 0.6 57 4.3 0.0 5.6 5 1 1 6 6 6 0 HEAT-like repeat LCAT PF02450.10 EEB08035.1 - 2.7e-117 392.0 0.0 3.8e-117 391.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EEB08035.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EEB08035.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF900 PF05990.7 EEB08035.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) 2-oxoacid_dh PF00198.18 EEB08036.1 - 4.7e-80 268.1 0.0 6e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEB08036.1 - 6.9e-18 64.0 0.7 1.4e-17 63.1 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EEB08036.1 - 0.0033 17.1 0.1 0.031 13.9 0.0 2.2 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EEB08036.1 - 0.017 14.8 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EEB08036.1 - 0.041 13.5 0.1 3.4 7.4 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_2 PF12700.2 EEB08036.1 - 0.1 11.7 0.1 2.1 7.4 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein PAT1 PF09770.4 EEB08036.1 - 5.9 5.0 8.6 7.7 4.6 6.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OMPdecase PF00215.19 EEB08037.1 - 1.7e-81 272.8 0.0 2e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Redoxin PF08534.5 EEB08038.1 - 7e-31 106.7 0.1 7.7e-31 106.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEB08038.1 - 2.9e-11 43.1 0.0 3.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glycos_transf_3 PF00591.16 EEB08039.1 - 7.2e-85 284.4 0.0 1e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EEB08039.1 - 0.0045 16.5 0.0 0.026 14.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Band_7 PF01145.20 EEB08040.2 - 2e-24 86.4 0.0 3.8e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family RLL PF10036.4 EEB08040.2 - 0.027 13.9 1.5 0.055 12.8 1.0 1.6 1 1 0 1 1 1 0 Putative carnitine deficiency-associated protein Band_7_1 PF13421.1 EEB08040.2 - 0.031 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Vma12 PF11712.3 EEB08041.1 - 0.03 14.0 2.7 0.047 13.3 1.9 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Period_C PF12114.3 EEB08041.1 - 5.8 6.4 12.4 8.3 5.9 8.6 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Motile_Sperm PF00635.21 EEB08042.1 - 1.4e-23 82.5 0.1 2.8e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO PF00650.15 EEB08044.1 - 4.8e-23 81.4 0.1 2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEB08044.1 - 3.5e-07 30.2 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEB08044.1 - 3.5e-07 30.2 0.2 1e-06 28.7 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UbiA PF01040.13 EEB08045.1 - 6.5e-27 94.3 18.3 9.3e-27 93.8 12.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1772 PF08592.6 EEB08045.1 - 8.5 6.1 9.8 0.14 11.9 0.3 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) PfkB PF00294.19 EEB08046.1 - 1.3e-65 221.5 3.4 1.4e-65 221.3 2.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEB08046.1 - 2.6e-08 33.3 0.1 4.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase zf-RING_2 PF13639.1 EEB08047.1 - 2.8e-10 39.8 8.8 6.3e-10 38.7 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB08047.1 - 8e-08 32.1 8.9 1.7e-07 31.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB08047.1 - 1.4e-07 31.0 8.3 2.6e-07 30.1 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB08047.1 - 2.5e-07 30.2 8.1 4.1e-07 29.5 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEB08047.1 - 0.00021 21.3 7.2 0.00092 19.2 5.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEB08047.1 - 0.00088 18.9 7.6 0.0015 18.1 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 EEB08047.1 - 0.05 13.1 8.8 0.1 12.1 6.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cyclotide PF03784.8 EEB08047.1 - 0.15 11.9 1.1 0.32 10.9 0.8 1.5 1 0 0 1 1 1 0 Cyclotide family Prok-RING_4 PF14447.1 EEB08047.1 - 0.68 9.5 8.9 1.5 8.4 4.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EEB08047.1 - 2.4 7.6 8.6 7.6 6.1 6.0 1.8 1 1 0 1 1 1 0 P-11 zinc finger Ribosomal_L13 PF00572.13 EEB08048.1 - 5.8e-43 146.0 0.0 7.7e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Gate PF07670.9 EEB08049.1 - 6.6 6.6 10.6 21 5.0 2.2 2.7 1 1 1 2 2 2 0 Nucleoside recognition RNase_PH PF01138.16 EEB08050.2 - 9.7e-33 113.2 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEB08050.2 - 6.8e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ACPS PF01648.15 EEB08051.1 - 5.3e-17 61.7 0.1 6.3e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.7 EEB08052.1 - 9.1e-96 320.8 0.8 1.6e-95 320.0 0.6 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 EEB08052.1 - 0.0022 17.6 0.1 0.055 13.1 0.0 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB z-alpha PF02295.12 EEB08052.1 - 0.0026 17.4 0.1 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 Adenosine deaminase z-alpha domain RPA_C PF08784.6 EEB08052.1 - 0.015 15.7 0.1 0.12 12.8 0.0 2.3 3 0 0 3 3 3 0 Replication protein A C terminal PadR PF03551.9 EEB08052.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_45 PF14947.1 EEB08052.1 - 0.076 12.8 0.2 0.69 9.7 0.2 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix MarR PF01047.17 EEB08052.1 - 0.11 12.2 0.2 1 9.1 0.1 2.5 3 0 0 3 3 3 0 MarR family HTH_36 PF13730.1 EEB08052.1 - 0.32 11.1 1.8 16 5.7 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Penicillinase_R PF03965.11 EEB08052.1 - 0.43 10.6 2.1 7.6 6.6 0.0 2.6 2 1 1 3 3 3 0 Penicillinase repressor DUF3414 PF11894.3 EEB08053.1 - 1.9e-196 654.9 40.6 2.7e-196 654.4 28.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) GATA PF00320.22 EEB08054.1 - 6.8e-11 41.3 3.7 1.8e-10 39.9 2.6 1.8 1 0 0 1 1 1 1 GATA zinc finger PP2C PF00481.16 EEB08055.1 - 2.5e-75 253.1 0.2 3e-75 252.8 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEB08055.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3595 PF12166.3 EEB08056.1 - 0.11 11.2 0.0 0.11 11.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3595) Med15 PF09606.5 EEB08056.1 - 0.12 10.4 37.6 0.15 10.2 26.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EEB08056.1 - 1.5 7.0 35.1 1.7 6.7 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med2 PF11214.3 EEB08056.1 - 4.5 7.3 9.8 0.18 11.8 0.5 2.8 2 1 0 2 2 2 0 Mediator complex subunit 2 NTP_transferase PF00483.18 EEB08057.1 - 6.1e-50 169.8 0.0 9.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EEB08057.1 - 7.6e-12 45.5 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EEB08057.1 - 2.3e-11 42.6 4.4 1.6e-09 36.7 1.3 3.5 2 1 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEB08057.1 - 7.1e-05 22.2 0.8 7.1e-05 22.2 0.6 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EEB08057.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EEB08057.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase CUE PF02845.11 EEB08058.1 - 2.5e-06 26.8 0.1 6.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 CUE domain 7TM_GPCR_Srx PF10328.4 EEB08058.1 - 0.11 11.6 0.2 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-CCCH PF00642.19 EEB08059.1 - 3.1e-10 39.5 11.5 4.7e-05 22.9 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEB08059.1 - 0.0038 17.1 16.0 0.24 11.4 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_L22 PF00237.14 EEB08060.1 - 6.5e-21 74.2 0.1 9.7e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e AAA_12 PF13087.1 EEB08061.2 - 1.8e-41 141.7 0.0 4.4e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEB08061.2 - 1e-27 97.2 1.1 7.6e-27 94.4 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB08061.2 - 8.2e-11 41.5 0.1 3.6e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEB08061.2 - 3.7e-09 36.4 0.0 4.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EEB08061.2 - 5.1e-06 25.9 0.8 5.1e-06 25.9 0.6 3.2 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EEB08061.2 - 0.00013 21.2 0.0 0.0003 20.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.13 EEB08061.2 - 0.00026 20.6 1.9 0.022 14.3 0.1 3.3 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEB08061.2 - 0.0004 20.2 0.0 0.0015 18.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEB08061.2 - 0.0026 16.8 0.0 0.0065 15.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EEB08061.2 - 0.01 15.3 0.3 0.023 14.1 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EEB08061.2 - 0.011 15.7 0.0 0.042 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EEB08061.2 - 0.017 14.5 0.0 0.051 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEB08061.2 - 0.034 14.3 0.9 0.21 11.8 0.6 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB08061.2 - 0.051 13.7 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEB08061.2 - 0.078 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 EEB08061.2 - 0.093 13.5 0.5 2.4 8.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain Podoplanin PF05808.6 EEB08062.1 - 2.2 7.7 5.1 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Podoplanin ADH_N PF08240.7 EEB08063.2 - 5.9e-33 112.8 0.6 1.5e-32 111.6 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB08063.2 - 2.7e-26 91.6 0.1 4.7e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB08063.2 - 7.7e-05 23.5 0.0 0.00018 22.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L14 PF00238.14 EEB08064.1 - 1.4e-34 118.5 0.0 1.5e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short PF00106.20 EEB08065.1 - 2e-24 86.3 0.3 3e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB08065.1 - 2.6e-17 63.4 0.3 3.7e-17 62.8 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB08065.1 - 2.2e-11 43.7 1.2 3.2e-11 43.2 0.5 1.5 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EEB08065.1 - 2.2e-06 27.2 0.1 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEB08065.1 - 0.00027 20.9 0.0 0.00045 20.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEB08065.1 - 0.0018 17.2 0.1 0.0026 16.6 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EEB08065.1 - 0.098 12.3 0.3 0.48 10.0 0.0 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EEB08065.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Cyto_heme_lyase PF01265.12 EEB08067.1 - 5.7e-72 242.4 0.4 2e-71 240.6 0.3 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ndc1_Nup PF09531.5 EEB08068.1 - 6e-81 272.6 14.8 7e-81 272.4 10.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Herpes_LMP1 PF05297.6 EEB08070.2 - 0.019 13.9 6.0 0.028 13.3 4.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FA_desaturase PF00487.19 EEB08070.2 - 0.73 9.2 6.4 2.7 7.3 4.4 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Lung_7-TM_R PF06814.8 EEB08071.1 - 1.2e-10 40.8 0.8 1.2e-10 40.8 0.6 1.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor PLA2_B PF01735.13 EEB08072.1 - 4.9e-176 585.7 3.7 5.7e-176 585.4 2.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.16 EEB08072.1 - 0.055 13.3 0.9 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 IBR domain Helicase_C_3 PF13625.1 EEB08073.1 - 1e-29 102.8 0.0 1.1e-28 99.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB08073.1 - 6.3e-15 55.4 0.4 4.2e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EEB08073.1 - 1.5e-11 43.6 0.1 2.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB08073.1 - 2.9e-11 43.0 0.0 6.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08073.1 - 1.9e-07 30.7 0.0 4.8e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase PF00069.20 EEB08076.1 - 1.1e-68 231.1 0.0 2.5e-68 230.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08076.1 - 3.7e-31 108.1 0.0 1e-29 103.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08076.1 - 1.5e-06 27.3 0.2 5.1e-05 22.3 0.1 2.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEB08076.1 - 0.0062 16.2 0.0 2.1 8.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEB08076.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.1 EEB08077.1 - 2.3e-44 151.0 0.5 3.5e-44 150.4 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EEB08077.1 - 1.7e-10 40.2 2.2 2e-05 24.0 0.3 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB08077.1 - 2.4e-05 23.9 5.8 0.00015 21.4 0.4 2.5 2 1 1 3 3 3 2 Leucine rich repeat GA PF01468.12 EEB08077.1 - 0.031 14.4 1.8 0.041 14.0 0.1 2.0 2 0 0 2 2 2 0 GA module LRR_7 PF13504.1 EEB08077.1 - 0.086 13.0 3.5 1.1 9.7 0.3 3.6 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EEB08077.1 - 0.37 11.0 3.9 34 5.0 0.2 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat Skp1_POZ PF03931.10 EEB08078.2 - 5.1e-15 55.3 0.2 7.5e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0300 PF08594.5 EEB08079.2 - 7.4e-55 185.1 0.5 1e-54 184.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Indigoidine_A PF04227.7 EEB08080.1 - 8.2e-126 419.1 0.7 1.2e-125 418.6 0.5 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EEB08080.1 - 3e-26 92.2 0.3 7.4e-25 87.6 0.0 2.7 2 1 0 2 2 2 1 pfkB family carbohydrate kinase RRM_1 PF00076.17 EEB08081.1 - 8.4e-49 163.0 0.0 2.8e-13 49.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08081.1 - 4.5e-46 154.7 0.1 4.9e-13 48.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08081.1 - 4.9e-24 83.9 0.0 1e-06 28.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EEB08081.1 - 1.6e-06 27.2 4.5 1.6e-06 27.2 3.1 2.1 2 0 0 2 2 2 1 Lsm interaction motif Nup35_RRM PF05172.8 EEB08081.1 - 0.00014 21.5 0.0 0.029 14.1 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Mak10 PF04112.8 EEB08082.2 - 3e-35 120.9 0.3 5.9e-35 119.9 0.2 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Abp2 PF09441.5 EEB08083.2 - 2e-60 203.7 0.0 3.1e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Mif2_N PF15624.1 EEB08084.2 - 2.2e-09 38.0 8.2 2.2e-09 38.0 5.7 4.7 1 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal F-box-like PF12937.2 EEB08085.1 - 5.4e-08 32.4 0.4 5.4e-08 32.4 0.3 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EEB08085.1 - 2e-06 27.2 2.9 2.3e-06 27.0 0.1 2.5 2 0 0 2 2 2 1 F-box domain MBT PF02820.13 EEB08085.1 - 0.055 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 mbt repeat Keratin_matx PF04579.7 EEB08085.1 - 0.1 12.8 0.3 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein Skp1 PF01466.14 EEB08086.1 - 1.1e-37 127.8 1.6 1.5e-37 127.4 0.3 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEB08086.1 - 1.6e-25 88.9 0.5 5.8e-25 87.1 0.2 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EEB08086.1 - 0.05 13.5 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain DUF2090 PF09863.4 EEB08086.1 - 0.052 12.3 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Mis12 PF05859.7 EEB08087.1 - 1.3e-31 109.3 0.8 2.4e-31 108.4 0.6 1.5 1 0 0 1 1 1 1 Mis12 protein Katanin_con80 PF13925.1 EEB08087.1 - 0.015 15.0 5.7 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 con80 domain of Katanin Macoilin PF09726.4 EEB08087.1 - 0.026 12.8 2.8 0.031 12.5 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Cyclin_N PF00134.18 EEB08087.1 - 0.062 12.8 0.6 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF2968 PF11180.3 EEB08087.1 - 0.14 11.5 11.2 0.57 9.5 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Nup54 PF13874.1 EEB08087.1 - 0.24 11.0 6.0 0.41 10.3 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 IncA PF04156.9 EEB08087.1 - 0.54 9.8 10.4 0.25 10.9 3.9 2.1 1 1 0 2 2 2 0 IncA protein MerR-DNA-bind PF09278.6 EEB08087.1 - 1.4 9.3 9.8 1.7 9.1 4.6 2.5 2 1 1 3 3 3 0 MerR, DNA binding Cortex-I_coil PF09304.5 EEB08087.1 - 1.9 8.5 7.5 2.8 8.0 4.3 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil Swi5 PF07061.6 EEB08088.2 - 2.1e-24 85.1 0.6 2.3e-24 84.9 0.4 1.0 1 0 0 1 1 1 1 Swi5 Prefoldin_2 PF01920.15 EEB08088.2 - 0.019 14.6 4.7 0.019 14.6 3.2 1.6 2 0 0 2 2 2 0 Prefoldin subunit TipAS PF07739.8 EEB08088.2 - 0.046 14.0 0.6 0.052 13.8 0.4 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF3584 PF12128.3 EEB08088.2 - 0.063 10.6 2.5 0.066 10.5 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4600 PF15372.1 EEB08088.2 - 0.079 13.1 5.0 0.15 12.3 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) bZIP_2 PF07716.10 EEB08088.2 - 0.096 12.5 6.9 0.2 11.4 4.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF4164 PF13747.1 EEB08088.2 - 0.1 12.7 2.4 0.14 12.3 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.4 EEB08088.2 - 0.11 12.3 3.1 0.13 12.1 2.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain THOC7 PF05615.8 EEB08088.2 - 0.13 12.5 2.4 0.16 12.2 1.7 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_1 PF00170.16 EEB08088.2 - 0.22 11.4 4.6 0.36 10.8 3.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor Cortex-I_coil PF09304.5 EEB08088.2 - 0.24 11.4 4.9 0.23 11.4 2.3 1.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil Med4 PF10018.4 EEB08088.2 - 0.39 10.0 4.1 0.61 9.4 2.8 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.17 EEB08088.2 - 0.4 10.7 3.9 0.71 9.9 2.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 EEB08088.2 - 0.42 10.3 5.5 0.47 10.1 3.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mei5 PF10376.4 EEB08088.2 - 1.2 8.5 6.3 3.7 7.0 4.4 1.7 1 1 0 1 1 1 0 Double-strand recombination repair protein M PF02370.11 EEB08088.2 - 4.9 7.8 8.5 3.5 8.3 1.7 2.6 1 1 1 2 2 2 0 M protein repeat NifU PF01106.12 EEB08089.1 - 4.8e-23 80.7 0.0 7.5e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EEB08089.1 - 0.0087 15.9 0.9 0.017 14.9 0.6 1.4 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Methyltransf_7 PF03492.10 EEB08089.1 - 0.046 12.4 3.4 0.061 12.0 2.4 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase IF4E PF01652.13 EEB08090.1 - 2e-53 180.3 0.2 2.4e-53 180.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mur_ligase_M PF08245.7 EEB08091.1 - 5.9e-07 29.7 0.9 9.1e-05 22.5 0.6 3.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EEB08091.1 - 0.017 15.1 0.0 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain LigB PF02900.13 EEB08092.2 - 1.4e-39 135.7 0.0 1.7e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CPSF100_C PF13299.1 EEB08093.1 - 3.8e-36 124.7 1.1 1.1e-35 123.1 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EEB08093.1 - 1.5e-25 89.5 0.0 4.2e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EEB08093.1 - 2.5e-06 27.1 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEB08093.1 - 0.00011 21.8 0.1 0.00023 20.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEB08093.1 - 0.0015 18.2 0.1 0.004 16.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EEB08093.1 - 0.0033 17.1 0.6 0.0078 15.9 0.4 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Transglut_core PF01841.14 EEB08094.1 - 1e-12 48.2 1.6 2.2e-12 47.1 1.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 EEB08094.1 - 6.5e-12 45.0 0.4 1.2e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Zn_Tnp_IS1595 PF12760.2 EEB08094.1 - 0.057 13.2 4.9 0.34 10.7 3.4 2.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain SET PF00856.23 EEB08095.1 - 6e-07 29.8 0.0 1.5e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 SET domain Drf_GBD PF06371.8 EEB08096.2 - 1.5e-19 70.1 2.2 2.3e-19 69.4 1.6 1.3 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain TrbI_Ftype PF09677.5 EEB08096.2 - 1.7 8.4 4.8 33 4.3 0.4 3.3 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) ING PF12998.2 EEB08097.1 - 2.6e-09 37.2 0.4 4.4e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEB08097.1 - 7.5e-09 35.1 7.8 1.3e-08 34.3 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EEB08097.1 - 0.0013 18.8 0.3 0.0028 17.7 0.2 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain LXG PF04740.7 EEB08097.1 - 0.0056 16.4 0.5 0.0086 15.8 0.4 1.3 1 0 0 1 1 1 1 LXG domain of WXG superfamily Fmp27_WPPW PF10359.4 EEB08097.1 - 0.029 12.8 0.1 0.061 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PHD_2 PF13831.1 EEB08097.1 - 0.085 12.1 3.0 0.18 11.1 2.1 1.6 1 0 0 1 1 1 0 PHD-finger HMA PF00403.21 EEB08098.1 - 6.3e-10 39.0 0.2 7.8e-10 38.7 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain MafB19-deam PF14437.1 EEB08098.1 - 0.0088 15.6 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase DUF2100 PF09873.4 EEB08098.1 - 0.014 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Yippee-Mis18 PF03226.9 EEB08098.1 - 0.16 12.0 0.4 0.39 10.8 0.1 1.6 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RRF PF01765.14 EEB08099.2 - 1.5e-26 92.8 11.3 1.5e-26 92.8 7.9 1.7 1 1 1 2 2 2 1 Ribosome recycling factor CHB_HEX PF03173.8 EEB08099.2 - 0.021 14.3 0.1 0.056 12.8 0.1 1.8 1 1 0 1 1 1 0 Putative carbohydrate binding domain DUF2175 PF09943.4 EEB08099.2 - 0.9 9.6 5.8 0.31 11.1 1.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF87 PF01935.12 EEB08099.2 - 3.2 7.5 10.7 5.6 6.7 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF87 Hydrolase_3 PF08282.7 EEB08099.2 - 4.1 6.8 7.4 0.82 9.1 0.8 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Myb_CC_LHEQLE PF14379.1 EEB08099.2 - 7.4 6.2 8.0 2.2 7.9 0.2 2.9 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif CPSF_A PF03178.10 EEB08100.1 - 4.5e-85 285.5 0.0 1.4e-84 283.9 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EEB08100.1 - 9.1e-19 66.9 0.0 1.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RNase_P_Rpp14 PF01900.14 EEB08101.2 - 0.00087 19.1 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family adh_short PF00106.20 EEB08102.1 - 2e-08 34.3 0.0 1.1e-06 28.6 0.0 2.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEB08102.1 - 3.5e-06 26.8 0.0 9.1e-06 25.4 0.0 1.6 1 1 1 2 2 2 1 KR domain Dus PF01207.12 EEB08103.1 - 2.1e-46 158.1 0.1 4.4e-46 157.1 0.1 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EEB08103.1 - 0.0021 17.1 0.0 0.013 14.6 0.0 2.2 1 1 1 2 2 2 1 Thiamine monophosphate synthase/TENI Toprim_3 PF13362.1 EEB08103.1 - 0.042 14.0 0.3 0.61 10.3 0.0 2.6 2 1 0 2 2 2 0 Toprim domain TIM PF00121.13 EEB08103.1 - 0.066 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Triosephosphate isomerase Glyco_tran_28_C PF04101.11 EEB08103.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain HSP70 PF00012.15 EEB08104.1 - 3.8e-241 801.2 10.6 4.2e-241 801.0 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB08104.1 - 7.4e-18 64.2 1.5 6.8e-17 61.0 0.4 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EEB08104.1 - 0.0017 17.4 0.7 0.012 14.7 0.1 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.5 EEB08104.1 - 0.007 15.2 1.3 0.14 10.9 0.1 2.7 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 EEB08104.1 - 0.0093 14.9 0.9 0.022 13.7 0.0 2.1 2 0 0 2 2 2 1 StbA protein RPA PF10134.4 EEB08104.1 - 0.021 14.1 0.2 0.056 12.7 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A FtsA PF14450.1 EEB08104.1 - 0.024 14.4 8.9 0.032 14.0 0.0 3.9 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.11 EEB08104.1 - 0.029 13.9 0.1 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pro_isomerase PF00160.16 EEB08105.1 - 3.1e-48 163.9 0.2 3.4e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3844 PF12955.2 EEB08106.2 - 1.2e-32 112.0 6.0 2.1e-32 111.2 4.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) AnfG_VnfG PF03139.10 EEB08106.2 - 0.011 15.5 0.1 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit PilS PF08805.6 EEB08106.2 - 0.029 13.9 0.2 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 PilS N terminal EGF PF00008.22 EEB08106.2 - 1 9.3 7.2 1.9 8.5 5.0 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.8 EEB08106.2 - 4 7.6 12.5 0.34 11.1 5.3 1.7 2 0 0 2 2 2 0 EGF-like domain Dus PF01207.12 EEB08107.2 - 1.1e-37 129.6 0.0 1.9e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EEB08107.2 - 0.0089 15.6 7.4 0.033 13.8 0.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3974 PF13120.1 EEB08107.2 - 0.1 12.4 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) zf-C2H2_jaz PF12171.3 EEB08108.1 - 0.00038 20.5 5.5 0.022 14.8 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEB08108.1 - 0.00065 19.8 11.0 0.043 14.1 0.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEB08108.1 - 0.012 15.9 18.3 0.11 12.8 2.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEB08108.1 - 0.024 14.9 21.9 0.055 13.8 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 EEB08108.1 - 0.21 11.8 3.7 0.45 10.7 1.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EEB08109.1 - 5.1e-188 625.3 0.0 6e-188 625.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEB08109.1 - 2.5e-42 144.0 0.0 4.3e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Bap31 PF05529.7 EEB08110.1 - 2.9e-52 176.9 7.0 3.3e-52 176.7 4.8 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Matrilin_ccoil PF10393.4 EEB08110.1 - 0.065 12.6 2.9 4.7 6.6 0.1 2.5 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spectrin PF00435.16 EEB08110.1 - 0.067 13.4 0.8 0.1 12.8 0.5 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF2085 PF09858.4 EEB08110.1 - 6.2 6.9 6.5 0.73 9.9 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) PHF5 PF03660.9 EEB08111.1 - 2.9e-49 165.5 11.3 3.4e-49 165.3 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EEB08111.1 - 1.1 9.1 15.3 12 5.7 10.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon Fer4_8 PF13183.1 EEB08111.1 - 1.6 8.8 15.2 1.8 8.6 0.1 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain PolC_DP2 PF03833.8 EEB08111.1 - 7.4 4.1 6.5 7.6 4.0 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Sec7 PF01369.15 EEB08112.1 - 2.1e-36 125.3 0.3 4.7e-36 124.2 0.2 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEB08112.1 - 9.3e-08 32.2 0.4 4.1e-07 30.1 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEB08112.1 - 2.6e-05 24.3 0.4 0.00017 21.7 0.3 2.5 1 1 0 1 1 1 1 PH domain PH PF00169.24 EEB08113.2 - 0.00014 21.9 0.3 0.0015 18.7 0.2 2.8 1 1 0 1 1 1 1 PH domain Myotub-related PF06602.9 EEB08114.2 - 1.4e-89 300.3 0.3 1.8e-89 300.0 0.2 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EEB08114.2 - 0.0021 18.3 0.0 0.0056 16.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEB08114.2 - 0.0041 16.5 0.0 0.0085 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EEB08114.2 - 0.0074 15.8 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain p450 PF00067.17 EEB08115.2 - 6.5e-56 189.7 0.0 8.5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 EEB08115.2 - 0.095 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX VHS PF00790.14 EEB08116.1 - 7.3e-37 126.1 1.2 1.3e-36 125.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EEB08116.1 - 3.5e-18 65.2 8.3 7.2e-18 64.2 5.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EEB08116.1 - 9e-09 34.1 12.8 0.00018 20.8 1.8 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif IBR PF01485.16 EEB08116.1 - 0.0013 18.5 2.2 0.0027 17.5 1.5 1.4 1 0 0 1 1 1 1 IBR domain FYVE_2 PF02318.11 EEB08116.1 - 0.005 16.7 3.9 0.005 16.7 2.7 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger zf-DHHC PF01529.15 EEB08116.1 - 0.064 12.6 0.3 0.064 12.6 0.2 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase adh_short PF00106.20 EEB08117.1 - 4.1e-13 49.5 0.0 9e-13 48.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEB08117.1 - 6e-08 32.5 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEB08117.1 - 0.00018 20.9 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEB08117.1 - 0.0005 19.9 0.0 0.00078 19.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEB08117.1 - 0.00067 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEB08117.1 - 0.007 16.3 0.1 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 EEB08117.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NmrA PF05368.8 EEB08117.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Brix PF04427.13 EEB08118.1 - 1.3e-48 165.1 0.0 1.9e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2945 PF11160.3 EEB08119.1 - 2e-09 37.1 0.4 7.2e-08 32.1 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) COXG PF06240.8 EEB08119.1 - 0.0082 15.8 0.1 0.0084 15.7 0.1 1.0 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Ribosomal_S14 PF00253.16 EEB08120.1 - 1.4e-18 66.0 0.6 1.5e-18 65.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PHD PF00628.24 EEB08121.2 - 6.4e-09 35.3 6.2 1.1e-08 34.6 4.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB08121.2 - 0.0039 16.4 4.9 0.0063 15.7 3.4 1.4 1 0 0 1 1 1 1 PHD-finger DRY_EERY PF09750.4 EEB08121.2 - 1.3 9.1 7.2 0.14 12.2 1.1 2.3 2 0 0 2 2 2 0 Alternative splicing regulator Aa_trans PF01490.13 EEB08122.1 - 1.3e-76 257.7 42.9 1.5e-76 257.5 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEB08122.1 - 4.9e-10 38.7 24.4 4.9e-10 38.7 16.9 1.9 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family PsbL PF02419.12 EEB08122.1 - 0.076 12.4 0.6 0.38 10.2 0.2 2.4 1 1 0 1 1 1 0 PsbL protein PAP_assoc PF03828.14 EEB08123.1 - 8.8e-18 64.0 0.4 1.8e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB08123.1 - 9.3e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PDZ_1 PF12812.2 EEB08124.2 - 6.3e-27 93.2 0.0 5.3e-23 80.6 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EEB08124.2 - 2.7e-09 36.7 0.0 0.0012 18.6 0.0 3.5 3 0 0 3 3 3 2 PDZ domain Trypsin_2 PF13365.1 EEB08124.2 - 4.5e-08 33.1 0.0 1.5e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EEB08124.2 - 1.9e-07 31.1 0.0 0.044 13.9 0.0 3.3 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EEB08124.2 - 0.019 14.7 0.1 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S3 PF00944.14 EEB08124.2 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_A4 PF01828.12 EEB08124.2 - 0.11 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase A4 family Peptidase_S46 PF10459.4 EEB08124.2 - 0.19 10.1 0.2 0.3 9.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase S46 Ax_dynein_light PF10211.4 EEB08125.1 - 0.13 12.0 7.0 0.14 11.9 3.5 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF2730 PF10805.3 EEB08125.1 - 0.16 11.6 1.2 0.8 9.4 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) GAS PF13851.1 EEB08125.1 - 0.18 10.9 7.0 0.093 11.9 0.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EEB08125.1 - 0.22 11.1 6.1 0.33 10.5 3.5 1.8 1 1 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 EEB08125.1 - 0.33 10.9 5.9 0.66 10.0 3.5 2.1 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EEB08125.1 - 0.85 9.1 4.3 1.3 8.5 0.3 2.8 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EEB08125.1 - 1 9.2 7.6 0.1 12.4 0.8 2.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEB08125.1 - 2.4 7.7 19.3 12 5.4 0.5 3.0 1 1 1 2 2 2 0 IncA protein DUF848 PF05852.6 EEB08125.1 - 2.8 7.7 9.8 1.1 9.0 2.1 2.9 1 1 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TBPIP PF07106.8 EEB08125.1 - 3.1 7.3 7.1 3.5 7.1 2.7 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 EEB08125.1 - 3.9 7.9 11.3 0.89 9.9 0.3 3.9 2 1 2 4 4 4 0 SlyX Fmp27_WPPW PF10359.4 EEB08125.1 - 3.9 5.7 8.9 5.8 5.2 3.6 2.4 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF4200 PF13863.1 EEB08125.1 - 7.3 6.5 12.1 0.68 9.8 1.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) ATP_synt_H PF05493.8 EEB08126.1 - 9.1e-20 70.5 2.1 1.1e-19 70.2 1.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4199 PF13858.1 EEB08126.1 - 0.01 15.7 1.1 0.012 15.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CopD PF05425.8 EEB08126.1 - 0.038 14.1 0.9 0.038 14.1 0.6 1.0 1 0 0 1 1 1 0 Copper resistance protein D DUF4149 PF13664.1 EEB08126.1 - 0.046 13.7 0.3 0.051 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4418 PF14387.1 EEB08126.1 - 0.091 12.5 0.2 0.099 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DUF2878 PF11086.3 EEB08126.1 - 0.14 12.1 2.6 0.15 12.0 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) SdpI PF13630.1 EEB08126.1 - 0.29 10.8 2.4 0.32 10.7 1.7 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family Rab5ip PF07019.7 EEB08126.1 - 1.3 9.2 4.1 2.4 8.3 2.9 1.5 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Peptidase_S24 PF00717.18 EEB08127.1 - 1.5e-07 30.9 0.2 2.6e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like UN_NPL4 PF11543.3 EEB08127.1 - 0.15 12.3 0.0 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Ribosomal_L7Ae PF01248.21 EEB08128.1 - 9.3e-29 98.7 0.7 1.2e-28 98.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CCAP PF11105.3 EEB08128.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a DSPc PF00782.15 EEB08129.1 - 6.9e-29 100.1 0.0 1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEB08129.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEB08129.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0066 PF01980.11 EEB08130.1 - 0.084 12.8 0.2 0.34 10.8 0.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0066 LMBR1 PF04791.11 EEB08131.2 - 1.3e-46 159.1 20.9 3.6e-46 157.7 14.5 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein ELFV_dehydrog PF00208.16 EEB08132.1 - 2.9e-79 266.0 1.3 3.5e-79 265.8 0.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EEB08132.1 - 9.1e-45 151.4 0.0 2.1e-44 150.2 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 EEB08132.1 - 0.033 13.3 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EEB08132.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HEAT PF02985.17 EEB08133.1 - 3.5 7.9 8.4 1.2 9.3 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat ArfGap PF01412.13 EEB08134.1 - 2.7e-35 120.6 0.1 2.7e-35 120.6 0.1 2.9 2 2 2 4 4 4 1 Putative GTPase activating protein for Arf EMP24_GP25L PF01105.19 EEB08136.1 - 5.4e-40 137.0 3.4 6.2e-40 136.8 2.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Orbi_VP6 PF01516.11 EEB08136.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 IPP-2 PF04979.9 EEB08137.1 - 1.2e-09 38.4 10.7 3.1e-08 33.9 7.4 2.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DnaJ_CXXCXGXG PF00684.14 EEB08138.1 - 0.0068 16.4 8.8 0.26 11.3 1.2 2.5 2 1 0 2 2 2 2 DnaJ central domain zf-C3HC4_3 PF13920.1 EEB08138.1 - 0.17 11.5 4.0 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TP6A_N PF04406.9 EEB08139.2 - 1.2e-18 66.4 0.1 2.6e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EEB08139.2 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF2220 PF09983.4 EEB08139.2 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) RE_Alw26IDE PF09665.5 EEB08139.2 - 0.11 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) TPR_11 PF13414.1 EEB08140.1 - 1.2e-11 44.0 0.2 9.1e-10 38.0 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEB08140.1 - 1.5e-07 30.6 0.5 0.00043 19.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEB08140.1 - 3.1e-07 29.7 0.4 0.0021 17.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB08140.1 - 2.3e-06 27.4 0.2 0.00081 19.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.26 EEB08140.1 - 8.2e-06 25.5 0.0 6.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain TPR_16 PF13432.1 EEB08140.1 - 0.00059 20.4 2.7 0.0074 16.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EEB08140.1 - 0.00073 19.2 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 EEB08140.1 - 0.0026 18.0 0.6 0.31 11.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08140.1 - 0.02 15.4 0.5 1.4 9.7 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EEB08140.1 - 0.025 14.7 0.1 0.15 12.2 0.1 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MAS20 PF02064.10 EEB08140.1 - 0.045 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 MAS20 protein import receptor DUF2184 PF09950.4 EEB08140.1 - 0.059 12.4 1.5 0.18 10.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) TPR_8 PF13181.1 EEB08140.1 - 0.081 12.7 0.0 24 5.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.17 EEB08141.1 - 4.4e-77 257.4 0.5 5.3e-77 257.1 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EEB08141.1 - 3.7e-05 23.5 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein Peptidase_M20 PF01546.23 EEB08141.1 - 0.046 13.2 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF2703 PF10865.3 EEB08141.1 - 0.32 10.9 1.4 0.66 9.9 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) XRN_N PF03159.13 EEB08142.1 - 2.4e-103 344.6 0.1 3.9e-103 343.9 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus tRNA-synt_1c PF00749.16 EEB08143.1 - 8.3e-107 356.4 0.0 1.8e-106 355.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEB08143.1 - 8.5e-36 123.2 0.9 2.6e-35 121.6 0.4 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EEB08143.1 - 9.5e-07 29.2 0.2 2.9e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEB08143.1 - 0.018 14.9 0.2 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EEB08143.1 - 0.026 13.6 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 EEB08143.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hid1 PF12722.2 EEB08144.2 - 1.3e-141 473.1 7.9 1.6e-141 472.8 5.4 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEB08144.2 - 1.6e-50 172.0 0.0 3e-50 171.0 0.0 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Voldacs PF03517.8 EEB08145.1 - 1.1e-25 90.0 1.1 1.5e-25 89.5 0.8 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Glyco_hydro_31 PF01055.21 EEB08146.1 - 1.2e-144 482.4 1.3 1.6e-144 482.0 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEB08146.1 - 4.2e-22 77.7 0.2 1.2e-21 76.3 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NPCC PF08058.6 EEB08147.1 - 1.6e-19 70.1 0.0 1.3e-12 47.8 0.0 2.4 1 1 1 2 2 2 2 Nuclear pore complex component Shugoshin_N PF07558.6 EEB08148.1 - 0.089 12.5 0.5 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region RRM_1 PF00076.17 EEB08149.2 - 2.8e-32 110.1 0.6 2.8e-12 46.0 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08149.2 - 7.4e-25 86.7 0.1 5.9e-09 35.7 0.1 3.9 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08149.2 - 1.9e-16 59.6 3.5 2.9e-07 30.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L1 PF00687.16 EEB08150.1 - 7.1e-26 90.9 0.1 8.4e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cementoin PF10511.4 EEB08150.1 - 0.061 13.0 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Trappin protein transglutaminase binding domain TAFII28 PF04719.9 EEB08151.1 - 9e-36 121.5 0.0 1.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Ribosomal_60s PF00428.14 EEB08151.1 - 0.072 13.4 0.1 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein JmjC PF02373.17 EEB08152.1 - 4.6e-42 142.8 0.6 1.1e-41 141.5 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EEB08152.1 - 1.2e-15 56.7 0.4 1.2e-15 56.7 0.3 1.9 2 0 0 2 2 2 1 jmjN domain ARID PF01388.16 EEB08152.1 - 0.00036 20.3 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EEB08152.1 - 0.00074 19.5 14.3 0.00074 19.5 9.9 1.9 2 0 0 2 2 2 1 C5HC2 zinc finger DUF4557 PF15101.1 EEB08153.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Acetyltransf_1 PF00583.19 EEB08154.1 - 5.2e-16 58.4 0.0 7.8e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB08154.1 - 5.3e-09 36.1 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB08154.1 - 3.4e-08 33.6 0.0 6.7e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB08154.1 - 1.8e-06 27.5 0.0 3.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EEB08154.1 - 0.00095 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB08154.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TBCA PF02970.11 EEB08154.1 - 0.09 12.8 2.0 0.1 12.6 0.6 1.6 1 1 1 2 2 2 0 Tubulin binding cofactor A RrnaAD PF00398.15 EEB08155.1 - 1.2e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pyr_redox_2 PF07992.9 EEB08156.1 - 2.9e-41 141.5 0.0 5e-41 140.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEB08156.1 - 4.1e-41 139.4 0.1 1.2e-40 138.0 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEB08156.1 - 6.8e-17 61.6 8.6 6.7e-16 58.4 1.6 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEB08156.1 - 4.9e-10 39.0 0.2 4.9e-10 39.0 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEB08156.1 - 6.9e-10 39.3 6.2 8.2e-06 26.0 1.4 3.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB08156.1 - 7.3e-08 32.3 5.7 0.00052 19.9 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EEB08156.1 - 1e-06 27.9 12.5 1.8e-06 27.1 2.1 3.1 2 2 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EEB08156.1 - 6.5e-06 25.4 8.6 0.0014 17.8 0.5 2.3 1 1 1 2 2 2 2 Thi4 family K_oxygenase PF13434.1 EEB08156.1 - 1.6e-05 24.0 0.1 0.0051 15.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EEB08156.1 - 2.4e-05 23.3 1.7 2.4e-05 23.3 1.2 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 EEB08156.1 - 7.4e-05 21.9 11.8 0.085 11.8 0.6 4.1 3 2 1 4 4 4 2 FAD binding domain HI0933_like PF03486.9 EEB08156.1 - 0.00033 19.2 13.3 0.015 13.7 0.4 3.8 3 1 1 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.16 EEB08156.1 - 0.0018 17.8 1.0 0.0095 15.5 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EEB08156.1 - 0.0032 17.1 0.6 0.0032 17.1 0.4 2.4 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EEB08156.1 - 0.0056 15.6 18.4 0.11 11.3 2.1 3.9 2 2 1 4 4 4 2 FAD dependent oxidoreductase SGT1 PF07093.6 EEB08157.1 - 4.2e-97 325.9 35.7 5.1e-85 286.0 0.3 2.2 1 1 1 2 2 2 2 SGT1 protein Gaa1 PF04114.9 EEB08158.1 - 1.7e-91 307.4 10.1 2.9e-88 296.7 2.2 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component Aldedh PF00171.17 EEB08159.2 - 7.3e-159 528.9 1.4 8.4e-159 528.7 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SUN PF03856.8 EEB08160.1 - 1.7e-96 322.3 16.7 2.3e-96 321.8 11.6 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) COX16 PF14138.1 EEB08161.1 - 2.5e-26 91.6 0.1 2.9e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF3311 PF11755.3 EEB08161.1 - 0.061 12.8 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Ribosomal_L11_N PF03946.9 EEB08162.1 - 3.3e-26 90.5 1.0 1.7e-25 88.2 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEB08162.1 - 4.5e-26 90.7 0.1 6.4e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NAPRTase PF04095.11 EEB08163.1 - 1.9e-62 210.7 0.4 2.5e-62 210.3 0.3 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Nup96 PF12110.3 EEB08164.1 - 1.6e-66 224.3 0.1 2.4e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EEB08164.1 - 5.6e-46 155.8 0.0 1e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EEB08164.1 - 2.4e-23 82.5 334.5 2e-06 28.0 21.0 9.0 2 2 7 9 9 9 8 Nucleoporin FG repeat region Kinetocho_Slk19 PF12709.2 EEB08165.1 - 0.00043 20.2 6.3 0.00043 20.2 4.4 20.8 12 6 11 24 24 24 5 Central kinetochore-associated GCFC PF07842.7 EEB08166.1 - 1.7e-54 185.0 7.4 1.7e-54 185.0 5.1 2.0 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EEB08166.1 - 1.4e-18 66.4 0.3 2.6e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEB08166.1 - 4.3e-10 39.2 0.2 1.3e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site TIP_N PF12457.3 EEB08166.1 - 0.008 16.2 1.9 0.008 16.2 1.3 2.2 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal DUF1896 PF08989.5 EEB08166.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) THP2 PF09432.5 EEB08166.1 - 2.2 8.1 8.0 0.14 12.0 1.2 2.2 2 0 0 2 2 2 0 Tho complex subunit THP2 UBA PF00627.26 EEB08167.1 - 0.027 14.2 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Rhomboid PF01694.17 EEB08167.1 - 0.057 13.4 7.4 0.028 14.4 3.4 1.8 1 1 1 2 2 2 0 Rhomboid family Sod_Fe_C PF02777.13 EEB08168.2 - 3.4e-34 116.8 1.7 6e-34 116.0 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEB08168.2 - 1.8e-27 95.4 5.3 3.1e-27 94.6 3.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acyltransferase PF01553.16 EEB08170.1 - 7e-14 51.4 0.0 7.8e-13 48.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF3902 PF13042.1 EEB08170.1 - 0.14 11.4 2.1 0.34 10.1 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Aminotran_1_2 PF00155.16 EEB08171.1 - 9e-79 265.0 0.0 1e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 EEB08171.1 - 0.0035 17.3 0.0 0.0095 15.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Endosulfine PF04667.12 EEB08172.1 - 6.4e-20 70.9 0.1 9.4e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1180 PF06679.7 EEB08172.1 - 0.73 9.7 5.2 1 9.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PP2C PF00481.16 EEB08173.1 - 7.4e-41 140.2 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEB08173.1 - 2.4e-06 27.0 0.1 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEB08173.1 - 0.038 13.6 0.1 0.54 9.9 0.0 2.7 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Glyco_tran_28_C PF04101.11 EEB08174.2 - 2.3e-28 98.9 0.0 2.6e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EEB08174.2 - 3.1e-07 29.9 0.0 3.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Aminotran_1_2 PF00155.16 EEB08175.1 - 5.5e-19 68.3 0.0 7.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EEB08175.1 - 0.17 10.3 0.0 0.31 9.5 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase ACC_central PF08326.7 EEB08176.1 - 3.3e-262 871.7 0.0 4.1e-262 871.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EEB08176.1 - 8.5e-175 581.8 0.0 1.1e-174 581.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEB08176.1 - 4.1e-52 176.5 0.0 8.1e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EEB08176.1 - 2.4e-24 85.5 0.1 5.4e-24 84.4 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEB08176.1 - 1.1e-20 73.5 0.0 1.5e-19 69.9 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EEB08176.1 - 9.7e-16 57.1 0.1 2.3e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEB08176.1 - 4.6e-12 46.0 0.0 1.4e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEB08176.1 - 0.00025 20.4 0.0 0.00063 19.1 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEB08176.1 - 0.0019 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEB08176.1 - 0.0071 16.2 0.0 0.046 13.5 0.0 2.4 4 0 0 4 4 2 1 ATP-grasp domain RimK PF08443.6 EEB08176.1 - 0.031 13.7 0.0 1.5 8.2 0.0 2.8 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Fer2_4 PF13510.1 EEB08176.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TFCD_C PF12612.3 EEB08176.1 - 0.081 12.3 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF788 PF05620.6 EEB08177.1 - 3.2e-40 137.7 0.4 3.6e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) G_glu_transpept PF01019.16 EEB08178.1 - 2.8e-163 544.0 0.0 3.2e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.13 EEB08178.1 - 0.073 11.7 0.2 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Asparaginase Acetyltransf_1 PF00583.19 EEB08179.2 - 0.0044 17.0 0.1 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB08179.2 - 0.0099 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB08179.2 - 0.02 14.7 0.1 0.047 13.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEB08179.2 - 0.096 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase YlaH PF14036.1 EEB08179.2 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 YlaH-like protein DUF3295 PF11702.3 EEB08180.1 - 3.8e-17 62.4 40.4 3.9e-15 55.8 28.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EEB08180.1 - 1.7e-11 43.4 4.1 3.7e-11 42.4 2.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.19 EEB08181.2 - 1.5e-147 492.1 3.0 1.8e-147 491.9 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EEB08181.2 - 0.074 12.9 2.2 10 6.0 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Hydrolase_like2 PF13246.1 EEB08181.2 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit PCI PF01399.22 EEB08182.2 - 5.2e-21 74.9 0.0 5.2e-21 74.9 0.0 2.9 4 0 0 4 4 4 1 PCI domain CtaG_Cox11 PF04442.9 EEB08183.1 - 5.4e-56 188.6 0.0 9.8e-56 187.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rsm22 PF09243.5 EEB08183.1 - 2.3e-44 151.4 0.0 3.8e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF2517 PF10725.4 EEB08183.1 - 0.06 13.0 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) SIP1 PF04938.7 EEB08184.1 - 3.5e-06 26.5 4.9 5e-06 26.0 3.4 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2b PF00587.20 EEB08184.1 - 0.044 13.3 0.1 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Pex2_Pex12 PF04757.9 EEB08185.1 - 3.4e-26 92.1 9.2 4.9e-26 91.5 6.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EEB08185.1 - 3.5e-05 23.7 5.1 3.5e-05 23.7 3.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB08185.1 - 4.3e-05 23.2 4.3 9.9e-05 22.0 3.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EEB08185.1 - 0.00014 21.6 7.0 0.00031 20.5 4.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EEB08185.1 - 0.00022 20.8 1.4 0.00045 19.8 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB08185.1 - 0.00038 20.0 3.2 0.00038 20.0 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Cut8_M PF14483.1 EEB08185.1 - 0.056 13.2 1.4 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 Cut8 dimerisation domain zf-rbx1 PF12678.2 EEB08185.1 - 0.13 12.4 3.1 0.25 11.4 1.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger U-box PF04564.10 EEB08185.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain PCI PF01399.22 EEB08186.1 - 1e-15 57.9 0.2 1e-15 57.9 0.2 2.3 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EEB08186.1 - 3.5e-07 30.0 0.1 1.1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 GntR PF00392.16 EEB08186.1 - 0.038 13.4 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Ribosomal_L37e PF01907.14 EEB08187.1 - 3.2e-27 94.0 11.2 6.1e-27 93.1 7.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EEB08187.1 - 0.0023 17.7 2.0 0.0035 17.1 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 EEB08187.1 - 0.068 12.9 2.1 0.11 12.2 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 EEB08187.1 - 0.076 12.2 1.5 4 6.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EEB08187.1 - 0.15 11.7 0.5 0.23 11.1 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EEB08187.1 - 0.16 11.6 3.5 0.26 11.0 2.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-CCHC_5 PF14787.1 EEB08187.1 - 0.34 10.4 3.7 0.67 9.4 2.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C3HC4_2 PF13923.1 EEB08187.1 - 0.98 9.5 4.9 1.5 8.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.7 EEB08187.1 - 2.2 7.7 5.0 11 5.5 3.4 2.1 1 1 1 2 2 2 0 HypF finger zf-H2C2_2 PF13465.1 EEB08187.1 - 6.9 7.1 9.0 7.1 7.1 2.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain AAA_13 PF13166.1 EEB08188.2 - 0.0022 16.5 18.0 0.0028 16.2 12.5 1.2 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.1 EEB08188.2 - 0.0061 16.0 18.5 0.0061 16.0 12.9 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF3497 PF12003.3 EEB08188.2 - 0.012 14.9 2.7 0.15 11.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3497) FUSC PF04632.7 EEB08188.2 - 0.043 12.2 1.3 0.055 11.8 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 EEB08188.2 - 0.049 12.8 6.8 0.074 12.2 4.7 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EEB08188.2 - 0.065 12.9 22.9 0.94 9.2 3.2 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding PilJ PF13675.1 EEB08188.2 - 0.18 12.1 4.9 0.65 10.3 0.3 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mnd1 PF03962.10 EEB08188.2 - 0.23 11.1 23.0 0.43 10.2 8.6 2.2 1 1 1 2 2 2 0 Mnd1 family IncA PF04156.9 EEB08188.2 - 0.37 10.3 29.9 1.1 8.8 4.1 2.7 1 1 0 2 2 2 0 IncA protein M_domain PF12938.2 EEB08188.2 - 0.4 10.4 7.7 0.46 10.2 2.2 2.5 1 1 1 2 2 2 0 M domain of GW182 DUF812 PF05667.6 EEB08188.2 - 0.51 8.7 19.5 0.71 8.3 9.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) LMBR1 PF04791.11 EEB08188.2 - 0.62 8.5 12.2 0.51 8.8 7.8 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Mod_r PF07200.8 EEB08188.2 - 0.77 9.6 25.0 3.8 7.4 1.3 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein L31 PF09784.4 EEB08188.2 - 0.89 9.6 7.1 2 8.5 0.4 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF972 PF06156.8 EEB08188.2 - 1.4 9.3 23.1 0.23 11.8 5.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) ApoO PF09769.4 EEB08188.2 - 1.7 8.3 8.2 0.9 9.2 3.0 2.1 1 1 1 2 2 2 0 Apolipoprotein O DUF4613 PF15390.1 EEB08188.2 - 1.9 6.5 13.3 2.5 6.1 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1664 PF07889.7 EEB08188.2 - 2.1 8.1 8.9 3.4 7.4 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EEB08188.2 - 2.4 7.9 26.1 0.68 9.7 11.4 2.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EEB08188.2 - 2.8 7.7 28.9 6.2 6.6 14.2 2.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EEB08188.2 - 5.2 6.7 26.0 1.2 8.8 5.2 4.1 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 USP8_interact PF08941.5 EEB08188.2 - 7.4 5.8 8.7 0.65 9.2 0.9 2.3 2 1 0 2 2 2 0 USP8 interacting tRNA_int_endo PF01974.12 EEB08189.1 - 7.3e-19 67.3 0.1 1.6e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EEB08189.1 - 0.0051 16.3 0.0 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain EOS1 PF12326.3 EEB08190.1 - 1.1e-50 171.1 7.2 1.1e-50 171.1 5.0 1.4 2 0 0 2 2 2 1 N-glycosylation protein Toxin_2 PF00451.14 EEB08190.1 - 7.6 6.7 6.9 2.5 8.2 0.5 2.2 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 DUF4613 PF15390.1 EEB08191.1 - 0.008 14.4 6.6 0.0096 14.1 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) zf-AD PF07776.10 EEB08191.1 - 0.017 15.1 0.3 0.049 13.6 0.0 2.0 2 0 0 2 2 1 0 Zinc-finger associated domain (zf-AD) Med9 PF07544.8 EEB08191.1 - 0.044 13.5 16.1 0.25 11.1 0.3 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.6 EEB08191.1 - 0.081 12.8 2.6 0.9 9.4 0.0 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 EEB08191.1 - 0.082 13.2 10.3 0.35 11.1 0.9 2.2 2 0 0 2 2 2 0 Striatin family Fib_alpha PF08702.5 EEB08191.1 - 0.083 13.0 10.9 4.4 7.4 0.9 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CCDC92 PF14916.1 EEB08191.1 - 0.083 12.4 0.3 0.083 12.4 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DivIC PF04977.10 EEB08191.1 - 0.1 12.1 0.2 0.1 12.1 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator Vps51 PF08700.6 EEB08191.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.2 3 0 0 3 3 3 0 Vps51/Vps67 Syntaxin-6_N PF09177.6 EEB08191.1 - 0.21 11.9 0.1 0.21 11.9 0.1 2.9 2 1 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EEB08191.1 - 0.25 11.6 1.4 16 5.8 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RBD-FIP PF09457.5 EEB08191.1 - 0.29 10.9 9.6 0.59 9.9 0.4 2.6 2 0 0 2 2 2 0 FIP domain FlxA PF14282.1 EEB08191.1 - 0.34 10.8 8.7 0.76 9.7 0.1 3.3 3 0 0 3 3 3 0 FlxA-like protein TMF_DNA_bd PF12329.3 EEB08191.1 - 0.41 10.4 19.2 1.7 8.5 1.1 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Syntaxin PF00804.20 EEB08191.1 - 0.46 10.6 0.1 0.46 10.6 0.1 3.2 2 1 0 2 2 1 0 Syntaxin Tnp_P_element PF12017.3 EEB08191.1 - 0.69 9.1 5.5 5.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Transposase protein FliJ PF02050.11 EEB08191.1 - 0.73 9.9 16.8 0.58 10.2 0.5 3.3 3 0 0 3 3 3 0 Flagellar FliJ protein DUF904 PF06005.7 EEB08191.1 - 0.74 10.1 9.0 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) ERM PF00769.14 EEB08191.1 - 0.92 8.9 15.1 6.7 6.1 7.3 2.6 2 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EEB08191.1 - 0.97 9.8 8.1 16 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MbeD_MobD PF04899.7 EEB08191.1 - 0.97 9.3 6.1 0.27 11.1 0.2 2.9 4 0 0 4 4 3 0 MbeD/MobD like Pox_A_type_inc PF04508.7 EEB08191.1 - 1.3 8.9 9.5 0.64 9.9 0.1 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3573 PF12097.3 EEB08191.1 - 1.5 7.3 4.8 1.9 7.0 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3573) Surfac_D-trimer PF09006.6 EEB08191.1 - 2.3 7.9 4.6 1.3 8.7 0.4 2.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation YPEB PF14620.1 EEB08191.1 - 4.4 6.2 8.9 11 4.8 0.8 2.7 1 1 2 3 3 3 0 YpeB sporulation Herpes_UL6 PF01763.11 EEB08191.1 - 6.3 4.8 10.1 0.5 8.4 1.2 2.3 2 1 0 2 2 2 0 Herpesvirus UL6 like YgaB PF14182.1 EEB08191.1 - 6.8 7.0 9.4 5.8 7.2 0.2 2.9 3 0 0 3 3 3 0 YgaB-like protein FtsJ PF01728.14 EEB08192.1 - 6.5e-24 84.9 0.1 9.9e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EEB08192.1 - 0.00079 19.8 0.1 0.052 14.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB08192.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB08192.1 - 0.0035 16.9 0.0 0.028 13.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB08192.1 - 0.023 14.6 0.0 0.053 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08192.1 - 0.029 14.9 0.0 0.046 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEB08192.1 - 0.063 12.7 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) OST3_OST6 PF04756.8 EEB08193.1 - 2.7e-23 82.2 5.7 2.7e-23 82.2 4.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 EEB08193.1 - 8.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEB08193.1 - 0.12 12.5 0.1 0.33 11.0 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Abi PF02517.11 EEB08193.1 - 3.8 7.7 6.1 12 6.1 4.2 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity Mito_carr PF00153.22 EEB08194.1 - 2.1e-65 216.4 3.6 9.1e-22 76.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 EEB08195.2 - 6.1e-28 97.7 0.8 6.1e-28 97.7 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Pput2613-deam PF14427.1 EEB08195.2 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase 6PF2K PF01591.13 EEB08196.1 - 5.2e-73 244.8 0.0 7.4e-73 244.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEB08196.1 - 9e-26 90.8 0.0 4.1e-25 88.7 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEB08196.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEB08196.1 - 0.00055 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EEB08196.1 - 0.014 16.1 0.0 0.036 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain GBP PF02263.14 EEB08196.1 - 0.069 12.2 0.1 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain HIG_1_N PF04588.8 EEB08197.2 - 7.1e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region RhoGAP PF00620.22 EEB08198.1 - 3e-21 75.6 0.0 6.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EEB08198.1 - 1.4e-17 63.9 0.0 3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SAM_2 PF07647.12 EEB08200.2 - 6.4e-14 51.5 0.2 1.2e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEB08200.2 - 2.2e-13 50.1 0.6 3.6e-13 49.4 0.4 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EEB08200.2 - 3.2e-09 37.1 0.0 6.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ste50p-SAM PF09235.5 EEB08200.2 - 0.00066 19.6 0.5 0.0014 18.6 0.3 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 EEB08200.2 - 0.018 14.7 0.4 0.045 13.5 0.3 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF2360 PF10152.4 EEB08200.2 - 2.4 8.4 7.7 5.1 7.3 5.4 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Utp8 PF10395.4 EEB08201.1 - 1.9e-05 23.1 0.5 0.15 10.3 0.0 3.8 3 1 0 3 3 3 3 Utp8 family Ras PF00071.17 EEB08202.1 - 1.1e-34 119.2 0.4 1.2e-34 119.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB08202.1 - 4.4e-22 78.7 0.1 1.1e-21 77.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEB08202.1 - 1.1e-08 34.4 0.2 1.3e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB08202.1 - 5.9e-07 28.8 0.3 7.2e-07 28.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEB08202.1 - 0.004 17.0 0.0 0.0069 16.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 EEB08202.1 - 0.0091 14.7 1.9 0.82 8.2 0.2 2.0 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EEB08202.1 - 0.011 14.4 0.8 0.026 13.2 0.0 1.9 2 1 1 3 3 3 0 G-protein alpha subunit TIP120 PF08623.5 EEB08203.1 - 2.8e-44 150.6 18.7 5.9e-44 149.6 1.9 5.3 3 1 2 5 5 5 2 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EEB08203.1 - 1.9e-09 36.7 7.1 0.2 11.7 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 EEB08203.1 - 1.2e-06 28.7 9.8 0.0018 18.4 0.2 5.9 7 1 0 7 7 7 2 HEAT repeats AAA PF00004.24 EEB08204.2 - 1.7e-98 325.9 0.0 1.1e-48 164.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEB08204.2 - 2.5e-20 72.2 2.4 4.8e-20 71.2 1.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EEB08204.2 - 1.5e-14 54.2 0.0 1.3e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEB08204.2 - 1.4e-13 50.4 0.0 1.5e-05 24.1 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEB08204.2 - 1.2e-12 47.9 0.0 1e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEB08204.2 - 7.4e-12 45.1 2.0 8.5e-06 25.5 0.0 4.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEB08204.2 - 9.9e-12 45.1 0.8 0.0024 18.0 0.1 4.9 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EEB08204.2 - 1.3e-11 45.3 0.6 0.00032 21.5 0.0 3.8 3 1 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EEB08204.2 - 1.3e-09 38.2 0.0 0.0034 17.4 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EEB08204.2 - 4.2e-09 35.6 2.4 0.001 17.8 0.0 2.9 3 1 0 3 3 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EEB08204.2 - 9.4e-09 34.9 0.0 0.00094 18.6 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEB08204.2 - 1.2e-08 34.3 0.2 0.0038 16.3 0.0 3.3 3 1 1 4 4 4 2 Zeta toxin CDC48_2 PF02933.12 EEB08204.2 - 1.9e-08 33.8 0.9 2.9e-08 33.2 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 EEB08204.2 - 3.7e-08 32.7 1.6 0.0023 17.1 0.0 3.0 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEB08204.2 - 3.9e-08 33.2 0.0 0.0031 17.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EEB08204.2 - 3.2e-07 29.9 4.5 0.04 13.3 0.1 4.5 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 EEB08204.2 - 5e-07 29.3 1.1 0.03 14.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EEB08204.2 - 7.2e-07 29.3 0.0 0.04 14.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EEB08204.2 - 8.4e-07 29.3 0.1 0.021 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EEB08204.2 - 3e-06 27.5 0.1 0.024 14.9 0.0 4.1 4 1 0 4 4 2 1 ABC transporter ResIII PF04851.10 EEB08204.2 - 3.2e-06 27.0 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EEB08204.2 - 3.7e-06 26.0 0.0 0.014 14.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EEB08204.2 - 4.1e-06 26.8 0.4 0.076 12.9 0.0 3.1 4 0 0 4 4 2 2 AAA domain KaiC PF06745.8 EEB08204.2 - 4.5e-06 25.9 1.1 0.45 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.21 EEB08204.2 - 1.4e-05 24.6 0.1 0.44 9.9 0.0 3.7 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEB08204.2 - 1.5e-05 24.7 0.1 3.4 7.3 0.0 4.4 3 2 2 5 5 5 0 Archaeal ATPase AAA_24 PF13479.1 EEB08204.2 - 1.6e-05 24.5 0.1 0.27 10.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.8 EEB08204.2 - 2.2e-05 23.5 0.0 0.019 13.9 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EEB08204.2 - 2.7e-05 24.2 0.0 0.37 10.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EEB08204.2 - 7e-05 22.1 0.2 0.27 10.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 EEB08204.2 - 7.4e-05 22.4 0.1 0.2 11.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.1 EEB08204.2 - 0.00012 21.7 0.0 0.35 10.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EEB08204.2 - 0.00021 21.0 0.0 0.52 9.9 0.0 3.0 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_3 PF07726.6 EEB08204.2 - 0.00025 20.6 0.0 0.91 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EEB08204.2 - 0.00043 19.9 0.7 0.96 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EEB08204.2 - 0.001 18.8 0.4 0.79 9.4 0.0 4.3 4 0 0 4 4 4 1 NTPase DUF2075 PF09848.4 EEB08204.2 - 0.0011 18.0 0.0 1.2 7.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EEB08204.2 - 0.0017 17.8 0.9 0.3 10.4 0.1 3.7 3 1 0 4 4 4 1 AAA-like domain T2SE PF00437.15 EEB08204.2 - 0.0022 16.9 0.0 0.18 10.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EEB08204.2 - 0.0023 17.4 0.0 0.24 10.9 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EEB08204.2 - 0.0036 16.5 0.3 2 7.5 0.0 2.8 3 0 0 3 3 3 1 Isopentenyl transferase NB-ARC PF00931.17 EEB08204.2 - 0.0048 15.7 0.1 1.2 7.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Molydop_binding PF01568.16 EEB08204.2 - 0.005 16.6 0.2 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Vps4_C PF09336.5 EEB08204.2 - 0.0096 15.7 0.1 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain KTI12 PF08433.5 EEB08204.2 - 0.011 14.9 0.2 2.5 7.2 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 EEB08204.2 - 0.016 14.1 0.3 1.3 7.9 0.0 3.1 2 2 2 4 4 4 0 KAP family P-loop domain UPF0079 PF02367.12 EEB08204.2 - 0.031 13.9 0.1 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EEB08204.2 - 0.049 13.1 0.1 1.8 8.0 0.0 2.8 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EEB08204.2 - 0.082 13.2 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EEB08204.2 - 0.099 12.5 2.3 3.5 7.4 0.0 3.2 4 0 0 4 4 2 0 Shikimate kinase MobB PF03205.9 EEB08204.2 - 0.11 12.1 0.4 2.2 7.9 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.6 EEB08204.2 - 0.12 12.2 0.0 24 4.8 0.0 3.2 3 0 0 3 3 3 0 Torsin NusA_N PF08529.6 EEB08204.2 - 0.56 10.2 7.9 0.23 11.4 2.7 2.3 3 0 0 3 3 1 0 NusA N-terminal domain zf-C2H2 PF00096.21 EEB08205.1 - 0.034 14.4 0.1 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNARE PF05739.14 EEB08206.2 - 9.4e-13 47.6 3.0 9.4e-13 47.6 2.1 2.3 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 EEB08206.2 - 1e-05 25.1 4.8 1.3e-05 24.7 3.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3402 PF11882.3 EEB08206.2 - 0.061 12.3 4.7 0.074 12.0 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Syntaxin-6_N PF09177.6 EEB08206.2 - 0.44 10.9 8.7 0.16 12.3 2.8 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4315 PF14193.1 EEB08206.2 - 0.44 10.5 9.1 0.099 12.5 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Cortex-I_coil PF09304.5 EEB08206.2 - 1.6 8.7 14.9 2 8.4 3.6 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil XhlA PF10779.4 EEB08206.2 - 2.5 8.0 7.8 0.93 9.4 2.3 2.5 2 1 0 2 2 2 0 Haemolysin XhlA OmpH PF03938.9 EEB08206.2 - 3.6 7.5 15.3 0.2 11.5 6.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cluap1 PF10234.4 EEB08206.2 - 4.8 6.2 11.4 3.3 6.8 4.1 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 GHMP_kinases_N PF00288.21 EEB08209.2 - 4.2e-10 39.5 0.4 4.2e-10 39.5 0.3 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain TPR_11 PF13414.1 EEB08210.2 - 1.1e-33 114.6 10.0 3.4e-12 45.8 0.4 6.5 6 1 0 6 6 6 4 TPR repeat TPR_2 PF07719.12 EEB08210.2 - 1.2e-31 106.0 10.6 2.5e-05 23.8 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EEB08210.2 - 1.9e-31 106.3 6.9 2.1e-07 30.2 0.1 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEB08210.2 - 3.7e-24 82.6 5.0 4.7e-05 22.8 0.0 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EEB08210.2 - 5.4e-23 80.9 13.9 2.1e-17 63.0 0.5 5.5 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB08210.2 - 2e-22 78.8 14.9 6.1e-11 42.1 0.0 8.7 4 2 4 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08210.2 - 3.1e-15 55.3 0.4 1.1 10.1 0.1 8.7 4 2 4 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB08210.2 - 3.4e-15 54.5 4.2 0.099 12.4 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08210.2 - 5.8e-15 55.3 2.7 0.0057 16.9 0.0 7.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08210.2 - 1.9e-12 47.5 2.2 0.17 12.6 0.1 6.2 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEB08210.2 - 4.3e-08 32.7 0.2 3.5 8.0 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEB08210.2 - 4.4e-08 32.5 1.3 0.01 14.9 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEB08210.2 - 1.5e-07 31.0 0.0 1.7 8.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEB08210.2 - 2.1e-06 27.7 5.2 5.8 7.5 0.1 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat MIT PF04212.13 EEB08210.2 - 0.002 17.9 0.2 37 4.2 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EEB08210.2 - 0.015 15.1 0.1 1.9 8.3 0.0 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 EEB08210.2 - 0.027 14.3 4.0 18 5.2 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat APC8 PF04049.8 EEB08211.1 - 1.3e-39 135.1 1.7 2.7e-39 134.1 0.2 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EEB08211.1 - 6.1e-32 107.9 28.0 2.6e-05 23.6 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEB08211.1 - 2.2e-30 104.1 22.7 2.8e-08 33.2 1.0 7.3 4 1 1 7 7 7 5 TPR repeat TPR_2 PF07719.12 EEB08211.1 - 3.4e-27 92.1 34.2 0.00043 19.9 0.1 10.0 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EEB08211.1 - 1.3e-24 84.0 22.8 0.00021 20.8 0.0 9.8 7 1 3 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08211.1 - 2.3e-23 82.2 15.5 1.8e-05 25.2 0.1 7.4 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEB08211.1 - 1.6e-21 76.0 16.9 5.2e-06 26.3 0.0 6.7 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08211.1 - 6.6e-21 72.9 12.9 0.023 15.3 0.1 8.7 6 3 3 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 EEB08211.1 - 1.2e-13 50.1 13.7 0.054 13.7 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEB08211.1 - 3.2e-12 45.2 16.6 0.021 14.5 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08211.1 - 9.4e-12 45.1 19.5 0.0054 17.0 0.2 7.1 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEB08211.1 - 5.6e-09 35.8 25.6 0.64 10.5 0.1 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB08211.1 - 6.3e-09 35.8 22.8 0.091 12.9 0.6 6.1 3 1 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEB08211.1 - 1.6e-06 27.8 11.9 0.5 10.2 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat ChAPs PF09295.5 EEB08211.1 - 5.8e-05 22.0 0.2 0.34 9.6 0.0 3.5 3 2 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EEB08211.1 - 0.0055 16.6 1.9 2.5 8.0 0.0 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EEB08211.1 - 0.012 15.4 1.6 0.53 10.0 0.1 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.1 EEB08211.1 - 0.046 13.8 1.8 4.5 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEB08211.1 - 0.062 13.2 19.7 6.8 6.7 0.1 7.3 8 1 1 9 9 7 0 Tetratricopeptide repeat BTAD PF03704.12 EEB08211.1 - 1.3 9.3 6.7 2.4 8.4 2.2 3.0 2 1 0 2 2 2 0 Bacterial transcriptional activator domain PPR PF01535.15 EEB08211.1 - 4.8 7.3 6.2 14 5.9 0.1 4.4 4 0 0 4 4 4 0 PPR repeat polyprenyl_synt PF00348.12 EEB08212.1 - 9e-76 254.1 0.0 1.1e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase B56 PF01603.15 EEB08213.2 - 5.4e-160 532.4 8.7 8.4e-160 531.8 6.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PMSI1 PF15322.1 EEB08213.2 - 1.1 8.2 10.5 2.1 7.3 7.3 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Tau95 PF09734.4 EEB08214.2 - 2.8e-57 194.3 0.0 4e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit GATase_5 PF13507.1 EEB08215.2 - 5.9e-96 320.3 0.0 8.3e-96 319.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EEB08215.2 - 1.1e-45 155.3 0.1 2.6e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EEB08215.2 - 3.2e-24 84.9 0.0 1.2e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RdRP PF05183.7 EEB08216.1 - 6.9e-163 543.4 0.0 9.7e-163 542.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3442 PF11924.3 EEB08216.1 - 0.02 14.4 0.9 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3442) Vps51 PF08700.6 EEB08217.1 - 2.7e-11 43.1 3.9 2.7e-11 43.1 2.7 3.3 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 EEB08217.1 - 7.7e-06 25.8 5.3 7.7e-06 25.8 3.6 3.2 3 2 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 EEB08217.1 - 0.043 13.6 6.3 0.54 10.0 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) MAS20 PF02064.10 EEB08218.1 - 6.7e-20 71.2 3.1 2.9e-19 69.1 2.1 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor Prenyltrans_2 PF13249.1 EEB08219.1 - 1.9e-41 141.0 0.9 3.4e-21 75.7 0.0 5.2 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEB08219.1 - 1.6e-34 118.2 9.0 1e-13 51.2 0.0 5.4 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 EEB08219.1 - 3.6e-20 71.2 17.9 4.4e-07 29.3 1.7 7.4 7 1 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EEB08219.1 - 3.9e-05 22.9 0.9 2.8 7.0 0.0 4.5 3 1 1 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 EEB08219.1 - 0.00049 19.4 0.1 3.4 6.8 0.0 4.6 3 1 2 5 5 5 2 A-macroglobulin complement component Trigger_N PF05697.8 EEB08219.1 - 0.2 11.4 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) Rho_GDI PF02115.12 EEB08220.1 - 7.4e-58 195.2 0.1 8.5e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TPK_catalytic PF04263.11 EEB08221.2 - 7.8e-31 106.2 0.0 1.3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EEB08221.2 - 1.7e-14 53.2 0.0 3.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUDIX PF00293.23 EEB08221.2 - 5.8e-07 29.2 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain ABC_membrane PF00664.18 EEB08222.1 - 9.3e-103 343.4 45.5 3.2e-55 187.4 11.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEB08222.1 - 1.2e-66 223.1 0.0 5.8e-33 114.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEB08222.1 - 1.6e-13 50.4 0.1 7.8e-05 22.0 0.1 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEB08222.1 - 7e-11 42.6 0.0 0.0017 18.4 0.2 4.3 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EEB08222.1 - 1.2e-09 37.2 1.6 4.1e-05 22.3 0.0 3.9 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EEB08222.1 - 2.8e-07 29.9 1.7 0.00076 18.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEB08222.1 - 1.6e-06 28.2 0.0 0.056 13.4 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EEB08222.1 - 4.4e-06 27.5 0.0 0.13 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEB08222.1 - 6.7e-06 26.2 0.6 0.12 12.5 0.0 4.0 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEB08222.1 - 7.1e-06 25.2 0.0 0.13 11.4 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EEB08222.1 - 3.7e-05 23.5 1.3 0.1 12.5 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EEB08222.1 - 0.00034 20.5 0.2 0.82 9.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEB08222.1 - 0.00061 19.2 0.0 0.53 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEB08222.1 - 0.0039 17.5 0.1 0.31 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB08222.1 - 0.0083 16.4 0.0 5.3 7.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EEB08222.1 - 0.0093 15.6 0.3 6.8 6.3 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EEB08222.1 - 0.012 15.1 0.4 5.8 6.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 EEB08222.1 - 0.013 14.6 0.1 7.6 5.5 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.1 EEB08222.1 - 0.014 15.1 0.0 1.9 8.2 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EEB08222.1 - 0.016 15.2 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEB08222.1 - 0.023 14.1 1.5 5.6 6.3 0.0 3.5 5 0 0 5 5 3 0 AAA-like domain G-alpha PF00503.15 EEB08222.1 - 0.031 12.9 0.0 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.1 EEB08222.1 - 0.044 13.6 0.0 8.7 6.2 0.0 3.3 4 0 0 4 4 2 0 AAA domain DUF87 PF01935.12 EEB08222.1 - 0.046 13.5 0.1 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 YfiO PF13525.1 EEB08222.1 - 0.056 12.8 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein CDC45 PF02724.9 EEB08222.1 - 0.1 10.5 0.9 0.18 9.7 0.6 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_5 PF07728.9 EEB08222.1 - 0.11 12.1 0.3 27 4.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Ribosomal_L39 PF00832.15 EEB08223.1 - 1.4e-22 78.8 10.9 1.6e-22 78.6 7.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein DUF2205 PF10224.4 EEB08224.1 - 3.3e-07 29.7 1.0 3.5e-07 29.6 0.7 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) NEMO PF11577.3 EEB08224.1 - 0.034 13.8 0.8 0.04 13.6 0.5 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO His_kinase PF06580.8 EEB08224.1 - 0.041 13.8 0.5 0.043 13.7 0.4 1.1 1 0 0 1 1 1 0 Histidine kinase ASF1_hist_chap PF04729.8 EEB08225.1 - 5.6e-63 211.1 0.6 8.2e-63 210.6 0.4 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone SGT1 PF07093.6 EEB08225.1 - 0.0015 17.0 8.8 0.0015 17.0 6.1 1.0 1 0 0 1 1 1 1 SGT1 protein Daxx PF03344.10 EEB08225.1 - 1.3 7.3 32.1 1.7 7.0 22.2 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EEB08225.1 - 2.8 7.0 23.6 3.2 6.9 16.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EEB08225.1 - 6.5 4.5 32.4 7.3 4.3 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family AdoMet_MTase PF07757.8 EEB08226.1 - 3.7e-48 162.3 0.0 6.6e-48 161.4 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EEB08226.1 - 0.00033 20.3 0.0 0.00089 19.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEB08226.1 - 0.0063 16.2 0.0 0.14 11.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08226.1 - 0.0089 16.5 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB08226.1 - 0.053 13.1 0.1 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain COPI_assoc PF08507.5 EEB08227.1 - 1.3e-22 79.9 2.2 1.5e-22 79.7 1.5 1.0 1 0 0 1 1 1 1 COPI associated protein DUF1777 PF08648.7 EEB08228.1 - 5.3e-25 88.1 39.6 5.5e-24 84.8 27.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) DUF566 PF04484.7 EEB08228.1 - 1 8.8 10.0 1.2 8.6 7.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) ADH_N PF08240.7 EEB08229.2 - 4.3e-35 119.7 0.8 8.7e-35 118.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB08229.2 - 5e-26 90.7 0.3 7.5e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEB08229.2 - 0.00022 22.1 0.0 0.00041 21.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RuBisCO_large PF00016.15 EEB08229.2 - 0.079 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Gtr1_RagA PF04670.7 EEB08230.1 - 1.2e-71 240.5 1.7 1.6e-71 240.1 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EEB08230.1 - 2.1e-05 23.8 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EEB08230.1 - 0.00014 22.3 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EEB08230.1 - 0.0027 16.9 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEB08230.1 - 0.0039 17.1 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EEB08230.1 - 0.019 14.8 0.0 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain F_bP_aldolase PF01116.15 EEB08231.2 - 1.4e-92 309.9 0.0 1.5e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Septin PF00735.13 EEB08232.1 - 1.7e-88 296.3 0.0 2.2e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EEB08232.1 - 2.8e-06 26.8 0.1 0.00012 21.5 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EEB08232.1 - 7.7e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEB08232.1 - 0.00027 20.8 0.0 0.00056 19.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEB08232.1 - 0.00045 19.4 0.0 0.00095 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEB08232.1 - 0.003 17.7 0.8 0.0055 16.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EEB08232.1 - 0.0032 16.5 0.0 0.007 15.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.7 EEB08232.1 - 0.0061 15.7 0.1 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEB08232.1 - 0.016 14.7 0.1 0.7 9.3 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EEB08232.1 - 0.021 15.0 0.1 0.13 12.4 0.0 2.1 1 1 1 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 EEB08232.1 - 0.035 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EEB08232.1 - 0.041 14.1 0.3 0.16 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF1947 PF09183.5 EEB08232.1 - 0.055 13.2 0.2 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Ras PF00071.17 EEB08232.1 - 0.056 12.8 0.0 0.17 11.2 0.0 1.8 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.1 EEB08232.1 - 0.059 13.3 1.2 0.56 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain KAP_NTPase PF07693.9 EEB08232.1 - 0.095 11.6 0.4 0.16 10.9 0.2 1.7 1 1 0 1 1 1 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 EEB08232.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EEB08232.1 - 0.1 12.8 0.1 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEB08232.1 - 0.11 12.3 1.5 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEB08232.1 - 0.14 12.4 0.1 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Metal_resist PF13801.1 EEB08232.1 - 7.2 6.6 8.4 33 4.4 5.5 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Exo_endo_phos PF03372.18 EEB08233.2 - 2.6e-18 66.8 0.1 6.2e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.1 EEB08233.2 - 0.027 13.9 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 EEB08234.1 - 1.4e-67 227.6 0.0 2.2e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08234.1 - 8.9e-48 162.6 0.0 1.5e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08234.1 - 8e-05 21.7 0.0 0.00021 20.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Abhydrolase_2 PF02230.11 EEB08235.1 - 5.4e-31 107.7 0.0 6.3e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEB08235.1 - 3.8e-06 26.7 0.0 7.3e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB08235.1 - 7e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EEB08235.1 - 0.0017 17.5 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EEB08235.1 - 0.022 13.6 0.0 0.16 10.8 0.0 2.2 2 1 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EEB08235.1 - 0.06 12.1 0.1 0.12 11.1 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase FSH1 PF03959.8 EEB08235.1 - 0.11 11.9 0.2 0.62 9.4 0.1 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) SH3_1 PF00018.23 EEB08237.2 - 4.6e-11 41.9 0.1 8.3e-11 41.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEB08237.2 - 2.1e-09 36.7 0.1 4.5e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EEB08237.2 - 2.2e-07 30.3 0.9 4.3e-07 29.4 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core PF01841.14 EEB08237.2 - 0.00019 21.6 0.0 0.00051 20.2 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 EEB08238.1 - 3.4e-50 166.2 27.7 9.3e-11 41.1 0.5 10.3 11 0 0 11 11 11 7 WD domain, G-beta repeat eIF2A PF08662.6 EEB08238.1 - 8.2e-10 38.7 0.6 0.0019 17.9 0.0 4.2 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EEB08238.1 - 4.3e-07 29.6 0.5 4.4e-05 23.0 0.4 2.6 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EEB08238.1 - 0.0001 22.4 0.4 28 5.1 0.0 5.6 5 0 0 5 5 5 0 PQQ-like domain Nbas_N PF15492.1 EEB08238.1 - 0.00049 19.3 0.3 3.6 6.5 0.1 4.0 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal BBS2_N PF14781.1 EEB08238.1 - 0.0017 18.0 0.1 4.4 6.9 0.0 4.0 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal PD40 PF07676.7 EEB08238.1 - 0.025 14.2 0.0 7.8 6.2 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ PF01011.16 EEB08238.1 - 3.8 7.2 7.1 23 4.7 0.3 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat 60KD_IMP PF02096.15 EEB08239.1 - 1.5e-39 135.7 3.6 1.5e-39 135.7 2.5 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein Ribosomal_L7Ae PF01248.21 EEB08240.2 - 3.8e-27 93.6 0.0 4.5e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.20 EEB08241.1 - 4.8e-63 212.7 0.0 8.4e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08241.1 - 1.2e-36 126.0 0.0 2.3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08241.1 - 1.6e-06 27.3 0.0 3.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB08241.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vac_ImportDeg PF09783.4 EEB08242.1 - 7.9e-52 175.3 0.5 9.1e-52 175.1 0.4 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pkinase PF00069.20 EEB08243.1 - 7.3e-41 140.0 0.0 9.3e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08243.1 - 3.9e-25 88.4 0.0 4.5e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08243.1 - 1.4e-06 27.4 0.0 0.00018 20.5 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Choline_kinase PF01633.15 EEB08243.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EEB08243.1 - 0.065 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEB08243.1 - 0.12 12.0 0.1 1.2 8.7 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family BAH PF01426.13 EEB08244.1 - 9.8e-17 60.8 0.2 4.1e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H_2 PF13832.1 EEB08244.1 - 4.6e-15 55.5 3.1 4.6e-15 55.5 2.1 4.4 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEB08244.1 - 8.8e-10 38.6 0.7 8.8e-10 38.6 0.5 5.2 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 EEB08244.1 - 1e-06 28.3 13.4 1e-06 28.3 9.3 6.5 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 EEB08244.1 - 0.0064 15.7 0.1 0.0064 15.7 0.1 5.9 5 0 0 5 5 5 3 PHD-finger zf-C2H2_4 PF13894.1 EEB08245.2 - 8.2e-08 32.0 12.1 0.00077 19.6 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEB08245.2 - 1.6e-07 31.2 19.6 3.6e-05 23.8 2.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEB08245.2 - 0.00036 20.6 1.3 0.00036 20.6 0.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEB08245.2 - 0.0032 17.5 6.5 0.69 10.1 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 EEB08245.2 - 0.029 12.8 0.3 0.044 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-met PF12874.2 EEB08245.2 - 0.24 11.6 4.0 2.3 8.5 0.4 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EEB08245.2 - 0.76 9.5 7.6 0.12 12.1 1.3 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EEB08245.2 - 0.81 9.6 5.4 5.1 7.1 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger ORC3_N PF07034.6 EEB08247.2 - 3.4e-11 42.7 0.0 5.5e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus PsbQ PF05757.6 EEB08247.2 - 0.36 10.2 3.6 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Peptidase_M16_C PF05193.16 EEB08248.1 - 1.5e-14 54.0 0.0 9.2e-11 41.7 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEB08248.1 - 1.9e-13 50.4 0.5 9.4e-13 48.1 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HCNGP PF07818.8 EEB08249.1 - 1.2e-18 66.8 0.1 1.9e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 HCNGP-like protein MDM31_MDM32 PF08118.6 EEB08250.2 - 1.1e-140 469.4 0.1 1.4e-140 469.0 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M48 PF01435.13 EEB08251.2 - 3.1e-52 177.3 0.0 4.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.4 EEB08251.2 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF1469 PF07332.6 EEB08251.2 - 2.4 7.9 5.0 0.81 9.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Arginase PF00491.16 EEB08252.1 - 2.2e-66 224.0 0.0 2.5e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1640 PF07798.6 EEB08253.1 - 5.9e-26 91.5 13.7 7.8e-26 91.1 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GCN5L1 PF06320.8 EEB08253.1 - 0.021 14.6 3.8 0.021 14.6 2.6 2.2 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) TBPIP PF07106.8 EEB08253.1 - 0.072 12.6 12.5 1.4 8.4 0.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE PF05008.10 EEB08253.1 - 0.51 10.5 10.9 0.91 9.7 3.9 3.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus HK97-gp10_like PF04883.7 EEB08253.1 - 0.53 11.2 2.8 4.7 8.2 0.2 2.6 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Taeniidae_ag PF05596.6 EEB08253.1 - 0.59 9.9 5.4 8 6.3 0.2 3.0 3 0 0 3 3 3 0 Taeniidae antigen UPF0449 PF15136.1 EEB08253.1 - 1.4 9.1 6.1 0.32 11.2 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Baculo_PEP_C PF04513.7 EEB08253.1 - 1.6 8.5 10.7 2 8.2 5.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YjgP_YjgQ PF03739.9 EEB08253.1 - 2.2 6.9 5.1 2.9 6.5 3.5 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family LEA_1 PF03760.10 EEB08253.1 - 2.6 8.2 6.2 0.53 10.4 1.4 2.0 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 DUF948 PF06103.6 EEB08253.1 - 3.1 7.7 7.5 4.1 7.3 0.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IFP_35_N PF07334.8 EEB08253.1 - 3.5 7.6 7.2 0.64 10.0 0.2 2.5 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Aa_trans PF01490.13 EEB08254.1 - 6.8e-89 298.1 39.6 8.3e-89 297.8 27.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3338 PF11819.3 EEB08254.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) AA_permease PF00324.16 EEB08255.1 - 3.1e-56 190.7 32.4 3.8e-56 190.3 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease Mhr1 PF12829.2 EEB08256.2 - 3.4e-27 94.1 0.1 4.8e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Atg14 PF10186.4 EEB08257.2 - 2.1e-52 177.9 3.9 2.9e-52 177.5 2.7 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HAUS4 PF14735.1 EEB08257.2 - 0.0026 17.1 7.1 0.0039 16.5 4.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 IncA PF04156.9 EEB08257.2 - 0.0087 15.6 12.4 0.017 14.7 8.6 1.4 1 0 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 EEB08257.2 - 0.012 14.8 0.9 0.019 14.1 0.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF445 PF04286.7 EEB08257.2 - 0.039 13.4 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4407 PF14362.1 EEB08257.2 - 0.15 10.9 4.4 0.24 10.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4445 PF14574.1 EEB08257.2 - 0.52 8.4 2.0 0.33 9.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) DUF1759 PF03564.10 EEB08257.2 - 1.7 8.4 7.1 1.5 8.6 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) SlyX PF04102.7 EEB08257.2 - 4.5 7.7 13.1 8.6 6.8 4.3 2.9 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.5 EEB08257.2 - 8.2 6.5 16.4 5.5 7.1 9.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LDB19 PF13002.2 EEB08258.1 - 4e-46 156.9 0.0 6.5e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EEB08258.1 - 0.00048 19.9 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEB08258.1 - 0.0047 17.0 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain FYVE PF01363.16 EEB08259.1 - 2.5e-16 59.3 8.8 3.9e-16 58.6 6.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EEB08259.1 - 1.4 8.8 8.7 0.18 11.6 3.0 1.7 2 0 0 2 2 2 0 IBR domain ATP-synt_C PF00137.16 EEB08260.1 - 6.3e-27 93.2 30.5 2.8e-15 55.9 5.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.8 EEB08260.1 - 5.4 5.0 7.5 0.72 7.9 1.1 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Metallopep PF12044.3 EEB08261.1 - 4.3e-138 460.3 0.0 5.6e-138 459.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EEB08261.1 - 1.2e-06 28.4 0.7 0.0038 17.1 0.0 2.6 1 1 1 2 2 2 2 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EEB08261.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EEB08261.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EEB08261.1 - 0.14 11.0 0.1 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EEB08261.1 - 0.18 12.3 0.4 0.39 11.2 0.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PCI PF01399.22 EEB08262.1 - 1.9e-11 44.1 0.0 4.9e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain IPK PF03770.11 EEB08263.2 - 2.8e-41 141.3 0.0 4.5e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_L7Ae PF01248.21 EEB08264.1 - 4.6e-27 93.3 0.0 5.7e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEB08264.1 - 0.002 17.9 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EEB08264.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain SRP9-21 PF05486.7 EEB08265.1 - 1.3e-19 69.6 0.1 2.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF4211 PF13926.1 EEB08266.1 - 2e-33 114.9 1.8 2e-33 114.9 1.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF822 PF05687.8 EEB08266.1 - 5.1 7.4 8.3 0.3 11.4 0.7 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF822) Ebp2 PF05890.7 EEB08267.1 - 6.2e-86 288.0 22.0 6.2e-86 288.0 15.2 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF2422 PF10337.4 EEB08267.1 - 1.7 7.3 12.2 0.016 14.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF3505 PF12013.3 EEB08267.1 - 6.5 7.0 6.3 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Thioredoxin PF00085.15 EEB08268.1 - 5.6e-57 189.8 0.0 7.7e-28 96.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EEB08268.1 - 6.7e-20 71.5 0.0 1.7e-19 70.2 0.0 1.7 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 EEB08268.1 - 6.9e-11 42.0 0.0 0.00036 20.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EEB08268.1 - 3e-10 40.2 0.3 0.001 19.2 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEB08268.1 - 1.6e-09 37.7 0.1 0.0022 18.0 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like AhpC-TSA PF00578.16 EEB08268.1 - 6.5e-07 29.0 0.0 0.023 14.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EEB08268.1 - 3.4e-06 26.6 0.2 0.077 12.5 0.1 2.2 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 EEB08268.1 - 0.00023 21.1 0.2 2.6 7.9 0.0 3.2 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 EEB08268.1 - 0.00025 20.8 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain TraF PF13728.1 EEB08268.1 - 0.0098 15.4 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 EEB08268.1 - 0.042 13.4 0.1 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin HEAT PF02985.17 EEB08268.1 - 0.083 13.0 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat Tom22 PF04281.8 EEB08269.1 - 2.5e-41 140.4 3.3 2.9e-41 140.2 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3722 PF12519.3 EEB08270.2 - 6.3e-55 186.1 0.6 4.3e-40 137.5 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3722) WD40 PF00400.27 EEB08271.1 - 3.4e-23 80.6 18.9 7.7e-07 28.7 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Tox-GHH PF15636.1 EEB08271.1 - 0.0059 16.2 0.1 3.3 7.4 0.0 2.9 3 0 0 3 3 3 2 GHH signature containing HNH/Endo VII superfamily nuclease toxin Nup160 PF11715.3 EEB08271.1 - 0.0069 14.5 1.4 2.5 6.1 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 STAG PF08514.6 EEB08272.1 - 5.8e-30 103.4 0.9 2.3e-29 101.5 0.6 2.1 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EEB08272.1 - 0.00036 20.7 0.0 0.037 14.3 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats HSP70 PF00012.15 EEB08272.1 - 0.14 10.0 0.0 0.21 9.4 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein UPF0137 PF03677.8 EEB08273.1 - 1.9 7.9 6.5 1.9 7.9 1.4 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0137) SieB PF14163.1 EEB08273.1 - 3 7.3 5.7 0.55 9.7 0.2 2.4 3 0 0 3 3 3 0 Superinfection exclusion protein B Asp_protease_2 PF13650.1 EEB08274.1 - 6.8e-07 29.6 0.0 2.1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EEB08274.1 - 1.4e-06 28.1 0.1 2.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEB08274.1 - 0.00028 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pkinase PF00069.20 EEB08275.1 - 9.2e-71 238.0 0.0 1.2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08275.1 - 3.8e-29 101.5 0.0 5.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEB08275.1 - 1.4e-05 24.5 0.1 2.7e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EEB08275.1 - 5.8e-05 22.1 0.0 0.00013 21.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB08275.1 - 0.0033 17.2 0.6 0.0062 16.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEB08275.1 - 0.0086 14.9 0.3 0.18 10.5 0.0 2.1 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEB08275.1 - 0.02 13.9 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEB08275.1 - 0.055 13.0 0.6 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase NCD1 PF04904.8 EEB08275.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Ribosomal_S9 PF00380.14 EEB08276.1 - 2.5e-38 131.0 1.1 2.8e-38 130.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EEB08276.1 - 0.041 11.3 0.0 0.045 11.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Exo70 PF03081.10 EEB08276.1 - 0.17 10.6 0.4 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_L13e PF01294.13 EEB08277.1 - 3.1e-72 241.8 3.8 3.9e-72 241.4 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sod_Fe_N PF00081.17 EEB08277.1 - 0.035 14.3 0.0 0.087 13.0 0.0 1.7 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribosomal_S11 PF00411.14 EEB08278.1 - 1.8e-41 140.7 1.0 2.1e-41 140.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 EEB08278.1 - 0.068 13.0 0.1 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Ribosomal_L30_N PF08079.7 EEB08279.1 - 5.3e-22 77.6 15.6 1.1e-21 76.6 10.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EEB08279.1 - 6.6e-20 70.4 1.4 9.6e-20 69.9 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF4594 PF15266.1 EEB08279.1 - 0.059 13.5 2.9 0.097 12.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) PPR_2 PF13041.1 EEB08280.1 - 6.8e-23 80.3 0.3 1.4e-19 69.7 0.1 3.9 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.1 EEB08280.1 - 3.3e-07 30.0 0.1 0.00013 22.0 0.0 3.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 EEB08280.1 - 7.1e-07 28.7 0.9 0.0014 18.4 0.0 4.7 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 EEB08280.1 - 0.005 16.2 1.1 0.21 11.1 0.0 3.6 5 0 0 5 5 5 1 PPR repeat Clathrin PF00637.15 EEB08280.1 - 0.28 10.7 5.4 0.71 9.4 0.0 3.0 2 1 1 3 3 3 0 Region in Clathrin and VPS DUF572 PF04502.8 EEB08281.2 - 4.1e-33 114.9 14.9 1.4e-32 113.2 10.3 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) Hydrolase_3 PF08282.7 EEB08281.2 - 0.14 11.7 1.8 0.21 11.1 1.2 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-CHY PF05495.7 EEB08282.2 - 2.9e-14 52.9 18.1 2.9e-14 52.9 12.5 3.5 3 0 0 3 3 3 2 CHY zinc finger UCH PF00443.24 EEB08283.2 - 2.6e-63 213.6 0.2 2.6e-63 213.6 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB08283.2 - 3.2e-25 89.1 1.1 3.5e-25 89.0 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.15 EEB08283.2 - 0.01 15.3 0.4 0.029 13.8 0.3 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger USP8_dimer PF08969.6 EEB08283.2 - 0.056 13.3 1.0 0.16 11.9 0.7 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain Rubredoxin PF00301.15 EEB08283.2 - 3.2 7.7 6.3 0.58 10.0 0.9 2.4 3 0 0 3 3 3 0 Rubredoxin zf-U1 PF06220.7 EEB08284.1 - 8.9e-13 47.5 1.0 1.8e-12 46.5 0.7 1.6 1 0 0 1 1 1 1 U1 zinc finger Chrome_Resist PF09828.4 EEB08284.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein zf-Dof PF02701.10 EEB08284.1 - 0.18 11.7 0.5 0.18 11.7 0.3 1.8 2 0 0 2 2 2 0 Dof domain, zinc finger CEP19 PF14933.1 EEB08284.1 - 0.18 12.0 4.7 0.47 10.7 3.1 1.7 1 1 1 2 2 2 0 CEP19-like protein WD40 PF00400.27 EEB08285.1 - 1e-11 44.2 0.6 1.1e-06 28.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 EEB08285.1 - 4.6e-05 21.7 0.3 0.056 11.5 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EEB08285.1 - 0.013 14.9 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain DUF4613 PF15390.1 EEB08285.1 - 0.088 10.9 0.0 0.16 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) WD40 PF00400.27 EEB08286.1 - 1.3e-20 72.4 6.4 1e-08 34.6 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF4420 PF14390.1 EEB08286.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) RRM_1 PF00076.17 EEB08287.2 - 2.1e-12 46.4 0.0 4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08287.2 - 3.7e-12 46.0 0.0 1.1e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08287.2 - 9.4e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 EEB08287.2 - 0.00024 20.0 4.5 0.00024 20.0 3.1 2.1 2 0 0 2 2 2 1 Plant specific eukaryotic initiation factor 4B Aminotran_3 PF00202.16 EEB08288.1 - 1.5e-86 290.3 0.0 1.8e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1770 PF08589.5 EEB08289.1 - 1.4e-08 35.2 1.3 1.9e-08 34.8 0.9 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) SMC_N PF02463.14 EEB08290.2 - 1.5e-26 93.0 0.0 3.2e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEB08290.2 - 8.3e-14 52.3 29.9 8.3e-14 52.3 20.7 5.8 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 EEB08290.2 - 1.1e-05 25.6 10.7 0.00012 22.1 3.4 3.3 3 1 0 3 3 3 1 AAA domain Spc7 PF08317.6 EEB08290.2 - 0.00021 20.1 13.9 0.00021 20.1 9.6 5.7 2 2 3 5 5 5 3 Spc7 kinetochore protein AAA_29 PF13555.1 EEB08290.2 - 0.00022 20.6 0.0 0.00063 19.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPV_P10 PF05531.7 EEB08290.2 - 0.00063 19.9 23.5 0.3 11.3 0.2 6.2 4 2 2 6 6 6 2 Nucleopolyhedrovirus P10 protein AAA PF00004.24 EEB08290.2 - 0.012 15.8 0.4 0.089 12.9 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEB08290.2 - 0.096 12.0 0.5 0.77 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Imm42 PF15601.1 EEB08290.2 - 0.17 11.3 8.8 0.16 11.3 0.3 3.8 3 1 1 4 4 4 0 Immunity protein 42 AAA_22 PF13401.1 EEB08290.2 - 0.22 11.6 4.7 0.86 9.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EEB08290.2 - 0.7 10.7 0.0 0.7 10.7 0.0 3.6 4 2 0 4 4 4 0 AAA domain DASH_Dad3 PF08656.5 EEB08291.1 - 3.3e-23 81.1 1.7 3.9e-23 80.9 1.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 EntA_Immun PF08951.5 EEB08291.1 - 0.0032 17.5 1.1 0.0055 16.8 0.8 1.4 1 0 0 1 1 1 1 Enterocin A Immunity Flagellar_rod PF05149.7 EEB08291.1 - 0.041 13.0 0.2 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein Ribosomal_S7e PF01251.13 EEB08291.1 - 0.1 12.0 0.7 0.18 11.2 0.2 1.5 1 1 1 2 2 2 0 Ribosomal protein S7e Vps51 PF08700.6 EEB08291.1 - 0.12 12.1 1.9 0.14 11.9 1.3 1.4 1 1 0 1 1 1 0 Vps51/Vps67 Syntaxin_2 PF14523.1 EEB08291.1 - 0.16 12.0 2.8 0.24 11.4 1.9 1.4 1 1 0 1 1 1 0 Syntaxin-like protein Pkinase PF00069.20 EEB08292.1 - 2.8e-64 216.7 0.0 3.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08292.1 - 3.3e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEB08292.1 - 3.7e-14 52.5 1.1 1.7e-13 50.4 0.3 2.4 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EEB08292.1 - 2e-08 33.5 0.0 3.6e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB08292.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pex16 PF08610.5 EEB08294.1 - 3.5e-40 138.0 2.5 4e-40 137.8 1.7 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SWIRM PF04433.12 EEB08295.2 - 6.9e-15 54.9 0.0 9.6e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain FYDLN_acid PF09538.5 EEB08295.2 - 0.15 12.6 0.4 0.45 11.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) VTC PF09359.5 EEB08296.1 - 4.3e-79 265.4 1.2 5.8e-79 265.0 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EEB08296.1 - 2.4e-19 70.1 13.4 9e-12 45.3 2.5 3.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EEB08296.1 - 8e-09 35.6 4.7 1.7e-08 34.5 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DDE_Tnp_ISL3 PF01610.12 EEB08296.1 - 0.038 13.5 1.4 0.068 12.7 0.6 1.6 1 1 0 1 1 1 0 Transposase FliD_C PF07195.7 EEB08296.1 - 0.088 12.0 0.3 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Remorin_C PF03763.8 EEB08296.1 - 0.14 11.6 1.1 0.29 10.6 0.8 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region NUDIX PF00293.23 EEB08297.1 - 1.9e-16 59.9 0.0 3.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_71 PF03659.9 EEB08298.1 - 2.9e-118 394.7 10.9 3.3e-118 394.5 7.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DASH_Duo1 PF08651.5 EEB08299.1 - 0.0019 17.7 0.1 0.046 13.3 0.0 2.6 3 0 0 3 3 3 1 DASH complex subunit Duo1 Hpt PF01627.18 EEB08299.1 - 0.3 11.1 1.7 17 5.5 0.0 2.9 2 1 1 3 3 3 0 Hpt domain Nexin_C PF08628.7 EEB08300.2 - 3.1e-06 27.2 0.3 7.7e-05 22.7 0.2 2.3 1 1 0 1 1 1 1 Sorting nexin C terminal MFS_1 PF07690.11 EEB08301.1 - 2.2e-20 72.6 28.8 9.3e-20 70.6 8.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEB08301.1 - 4e-08 31.8 0.7 4e-08 31.8 0.5 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Nab2 PF11517.3 EEB08302.2 - 0.002 18.1 0.1 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) NAD_binding_2 PF03446.10 EEB08302.2 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-CCCH_2 PF14608.1 EEB08302.2 - 2.1 8.4 7.3 46 4.2 0.2 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type MSC PF09402.5 EEB08303.1 - 9.4e-39 133.0 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EEB08303.1 - 2.7e-15 55.5 0.5 8.8e-15 53.9 0.1 2.1 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.22 EEB08303.1 - 0.058 12.9 0.1 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 SAP domain DUF2182 PF09948.4 EEB08303.1 - 0.17 11.7 0.2 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) DJ-1_PfpI PF01965.19 EEB08304.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.8 1 1 0 1 1 1 0 DJ-1/PfpI family ORC5_C PF14630.1 EEB08305.1 - 4.1e-64 216.6 0.2 6e-64 216.1 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EEB08305.1 - 3e-08 33.8 0.1 1.2e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.4 EEB08305.1 - 0.07 12.0 0.0 0.95 8.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EEB08305.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 EEB08306.1 - 1.1e-60 201.3 3.5 6.5e-21 73.8 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EEB08307.1 - 1e-59 200.5 0.1 1.2e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB08307.1 - 2.4e-21 76.4 0.0 3.5e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB08307.1 - 2e-09 36.9 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB08307.1 - 3.6e-07 29.7 0.1 3.3e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEB08307.1 - 5.7e-05 23.0 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 EEB08307.1 - 0.0016 17.4 0.0 0.17 10.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 EEB08307.1 - 0.019 14.5 0.4 0.3 10.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EEB08307.1 - 0.022 13.9 0.1 0.035 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EEB08307.1 - 0.029 13.5 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EEB08307.1 - 0.031 13.5 0.1 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 EEB08307.1 - 0.063 12.6 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEB08307.1 - 0.074 13.0 0.2 0.52 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain CPSF_A PF03178.10 EEB08308.1 - 1.7e-49 168.6 1.5 1.5e-47 162.2 0.0 3.4 5 1 1 6 6 6 2 CPSF A subunit region MMS1_N PF10433.4 EEB08308.1 - 4e-42 144.0 2.9 8.5e-42 142.9 2.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cofilin_ADF PF00241.15 EEB08309.1 - 1.3e-10 41.2 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_6 PF00970.19 EEB08310.1 - 3.4e-07 30.3 0.0 6.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEB08310.1 - 0.0013 19.2 0.0 0.003 18.1 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEB08310.1 - 0.048 13.5 0.1 0.52 10.2 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Arg_repressor_C PF02863.13 EEB08310.1 - 0.099 12.1 0.1 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain AA_kinase PF00696.23 EEB08311.1 - 2.4e-36 125.4 0.3 3.4e-36 125.0 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EEB08311.1 - 6.4e-17 61.0 0.1 1.6e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 PUA domain Nop52 PF05997.7 EEB08312.1 - 1.1e-60 204.8 0.5 1.3e-60 204.5 0.4 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Ribosomal_L18e PF00828.14 EEB08313.1 - 1.3e-17 64.4 0.1 1.9e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 LSM PF01423.17 EEB08314.1 - 3.9e-09 35.9 0.1 1.6e-08 33.9 0.1 1.8 1 1 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 EEB08315.1 - 2e-59 200.2 1.9 3e-59 199.6 1.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEB08315.1 - 6.2e-29 100.0 0.1 2.4e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEB08315.1 - 1.4e-16 60.3 3.5 1.4e-16 60.3 1.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB08315.1 - 6.6e-06 26.0 0.2 1.5e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EEB08315.1 - 5.6e-05 22.6 0.2 0.00016 21.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EEB08315.1 - 0.00016 22.1 0.1 0.00028 21.3 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Alba PF01918.16 EEB08315.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Alba PduV-EutP PF10662.4 EEB08315.1 - 0.014 14.9 0.8 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EEB08315.1 - 0.07 12.4 3.8 2.3 7.4 2.6 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.18 EEB08315.1 - 0.07 12.5 3.1 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Prefoldin_2 PF01920.15 EEB08316.1 - 6.3e-10 38.7 9.7 8.2e-10 38.4 6.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Acp26Ab PF05777.7 EEB08316.1 - 0.01 16.2 1.0 0.01 16.2 0.7 1.8 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) IL12 PF03039.9 EEB08316.1 - 0.059 12.4 0.1 0.064 12.3 0.1 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit SpoIISA_toxin PF14171.1 EEB08316.1 - 0.13 11.5 1.1 0.15 11.2 0.5 1.4 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system FliJ PF02050.11 EEB08316.1 - 0.19 11.8 4.8 0.41 10.6 1.4 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Y_phosphatase3 PF13350.1 EEB08316.1 - 0.23 11.7 1.7 0.29 11.3 1.2 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Occludin_ELL PF07303.8 EEB08316.1 - 0.32 11.7 3.8 0.44 11.3 2.6 1.3 1 0 0 1 1 1 0 Occludin homology domain Fib_alpha PF08702.5 EEB08316.1 - 0.57 10.3 10.5 7.2 6.7 7.2 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EEB08316.1 - 0.58 10.4 7.6 0.11 12.7 1.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EEB08316.1 - 0.71 9.9 10.2 1.1 9.3 0.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.1 EEB08316.1 - 0.8 9.7 4.6 2.9 7.8 3.2 1.8 1 1 0 1 1 1 0 Up-regulated During Septation TMCO5 PF14992.1 EEB08316.1 - 1.2 8.1 7.1 1.5 7.8 4.9 1.1 1 0 0 1 1 1 0 TMCO5 family Phage_GP20 PF06810.6 EEB08316.1 - 3.3 7.1 12.0 0.62 9.4 1.5 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fis1_TPR_C PF14853.1 EEB08317.1 - 4.7e-20 71.2 2.6 4.7e-20 71.2 1.8 1.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EEB08317.1 - 9.8e-14 50.3 0.2 2.4e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EEB08317.1 - 0.00012 21.6 2.0 0.00034 20.2 1.2 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08317.1 - 0.00093 19.8 2.3 0.044 14.4 0.2 1.8 1 1 2 3 3 3 2 Tetratricopeptide repeat UPF0118 PF01594.11 EEB08317.1 - 0.0016 17.4 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF20 TPR_6 PF13174.1 EEB08317.1 - 0.0033 17.7 1.0 0.01 16.2 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EEB08317.1 - 0.0064 16.6 0.1 0.0098 16.0 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB08317.1 - 0.012 15.4 0.3 0.029 14.3 0.2 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEB08317.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEB08317.1 - 0.017 14.7 0.5 0.03 13.9 0.4 1.5 1 1 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 EEB08317.1 - 0.025 14.9 0.2 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08317.1 - 0.045 14.4 0.1 0.13 12.9 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 EEB08317.1 - 0.05 12.3 0.2 0.054 12.2 0.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EF-hand_4 PF12763.2 EEB08318.1 - 3.8e-39 132.5 0.0 3e-38 129.7 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EEB08318.1 - 5.4e-18 65.3 6.3 2e-17 63.4 4.4 1.9 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_8 PF13833.1 EEB08318.1 - 1.3e-06 27.9 0.2 3.3e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EEB08318.1 - 1.9e-05 23.6 1.4 0.0001 21.3 1.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EEB08318.1 - 2.7e-05 24.1 0.2 0.00023 21.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EEB08318.1 - 0.00076 19.1 0.4 0.074 12.9 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain LRR_3 PF07725.7 EEB08318.1 - 0.033 13.9 0.1 0.086 12.6 0.1 1.8 1 0 0 1 1 1 0 Leucine Rich Repeat EF-hand_9 PF14658.1 EEB08318.1 - 0.037 13.9 0.3 0.3 11.0 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 EEB08318.1 - 0.096 12.0 1.0 0.3 10.5 0.7 1.9 1 0 0 1 1 1 0 EF hand DUF3752 PF12572.3 EEB08318.1 - 0.1 12.7 4.9 0.19 11.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Ribosomal_L10 PF00466.15 EEB08319.1 - 9.6e-19 67.1 0.0 1.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Sedlin_N PF04628.8 EEB08320.1 - 6.6e-47 158.6 0.7 7.4e-47 158.5 0.5 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEB08320.1 - 1.3e-11 44.3 0.6 2.5e-11 43.4 0.4 1.5 1 1 0 1 1 1 1 Sybindin-like family RNA_polI_A34 PF08208.6 EEB08321.1 - 7.7e-12 45.2 12.3 7.7e-12 45.2 8.5 1.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 LSM PF01423.17 EEB08322.1 - 7.6e-17 60.6 0.1 9e-17 60.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 EEB08323.1 - 2.2e-23 82.8 5.5 6.9e-23 81.1 0.1 3.6 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EEB08323.1 - 7.5e-08 32.1 1.3 2e-06 27.6 0.1 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 EEB08323.1 - 0.0023 17.8 0.0 0.11 12.5 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EEB08323.1 - 0.017 15.6 0.0 5.1 7.7 0.0 3.6 2 0 0 2 2 2 0 HEAT-like repeat Helitron_like_N PF14214.1 EEB08323.1 - 0.07 12.8 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus AMP-binding PF00501.23 EEB08324.1 - 1.3e-89 300.5 0.0 1.6e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme eIF3g PF12353.3 EEB08325.1 - 3.2e-46 156.4 1.1 4.3e-46 155.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EEB08325.1 - 1.3e-18 66.3 0.0 2.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08325.1 - 1.7e-13 50.3 0.0 4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08325.1 - 1.3e-07 31.2 0.0 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S4e PF00900.15 EEB08325.1 - 0.057 13.0 1.6 0.086 12.5 0.3 1.8 2 0 0 2 2 2 0 Ribosomal family S4e DUF2782 PF11191.3 EEB08325.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) zf-H2C2_2 PF13465.1 EEB08326.2 - 3.6e-10 39.6 15.9 3.8e-06 26.9 3.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEB08326.2 - 1.4e-08 34.5 12.3 0.00057 20.0 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB08326.2 - 2.9e-05 24.0 11.9 0.03 14.6 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger ATP-sulfurylase PF01747.12 EEB08327.1 - 1.7e-89 298.7 0.2 2.5e-89 298.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EEB08327.1 - 8.3e-50 168.3 0.0 1.4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain 60KD_IMP PF02096.15 EEB08328.1 - 2.7e-20 72.8 0.4 3.2e-20 72.6 0.3 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2975 PF11188.3 EEB08328.1 - 0.014 15.1 0.9 0.064 12.9 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ADH_zinc_N PF00107.21 EEB08329.1 - 1.9e-23 82.4 0.0 3.9e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEB08329.1 - 8.1e-15 54.5 0.2 1.8e-14 53.4 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEB08329.1 - 2.6e-13 50.9 0.1 1.6e-12 48.3 0.0 2.2 1 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF3773 PF12608.3 EEB08329.1 - 0.0026 17.7 0.2 2.2 8.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3773) DUF3250 PF11618.3 EEB08329.1 - 0.0079 16.3 0.1 0.066 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3250) DUF4547 PF15080.1 EEB08329.1 - 0.036 13.4 0.0 0.39 10.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4547) NAD_binding_10 PF13460.1 EEB08329.1 - 0.13 12.2 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Ist1 PF03398.9 EEB08330.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Amino_oxidase PF01593.19 EEB08330.1 - 0.15 11.0 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DEAD PF00270.24 EEB08331.2 - 3.3e-43 147.0 0.3 3.1e-42 143.9 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08331.2 - 8.4e-19 67.2 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB08331.2 - 3.7e-09 36.6 0.0 1.6e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EEB08331.2 - 0.00032 19.6 0.0 0.00081 18.2 0.0 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 EEB08331.2 - 0.073 12.8 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain EAF PF09816.4 EEB08332.1 - 4.4e-27 94.2 0.1 7.5e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Med3 PF11593.3 EEB08332.1 - 2.8 7.0 13.7 4.3 6.4 9.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PP2C PF00481.16 EEB08333.1 - 3.4e-85 285.5 0.0 4.4e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEB08333.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Recep_L_domain PF01030.19 EEB08334.1 - 4.9e-11 42.5 5.2 0.0034 17.3 0.2 5.0 1 1 4 5 5 5 3 Receptor L domain LRR_5 PF13306.1 EEB08334.1 - 0.00035 20.2 2.4 0.27 10.9 0.2 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) Ecm33 PF12454.3 EEB08334.1 - 0.0088 15.9 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Pepsin-I3 PF06394.8 EEB08334.1 - 0.012 15.2 0.1 0.087 12.5 0.0 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain BTD PF09270.5 EEB08335.2 - 1.4e-27 96.3 0.0 2.7e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EEB08335.2 - 3.1e-25 89.2 0.1 3.1e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 LAG1, DNA binding Chorismate_synt PF01264.16 EEB08336.1 - 3.6e-132 440.0 0.0 4.4e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase PNP_UDP_1 PF01048.15 EEB08336.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily Pkinase PF00069.20 EEB08337.2 - 4.8e-60 202.8 0.0 6.5e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08337.2 - 7.8e-33 113.6 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08337.2 - 1.4e-07 30.8 0.0 3.1e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like SET PF00856.23 EEB08338.1 - 1.3e-11 45.0 0.3 5.5e-10 39.7 0.0 2.1 1 1 1 2 2 2 2 SET domain DENN PF02141.16 EEB08339.1 - 2.5e-42 144.7 1.3 2.5e-42 144.7 0.9 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EEB08339.1 - 9.1e-14 51.1 2.4 2.6e-13 49.7 0.6 2.5 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 EEB08339.1 - 1.5e-10 40.9 0.6 5.4e-10 39.1 0.4 2.0 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 EEB08339.1 - 0.0075 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis UCR_14kD PF02271.11 EEB08341.1 - 2.4e-39 133.3 0.8 2.8e-39 133.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribosomal_S21 PF01165.15 EEB08341.1 - 0.4 10.1 2.9 0.62 9.5 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S21 Ima1_N PF09779.4 EEB08342.1 - 5.7e-34 117.4 5.3 1.9e-33 115.7 3.7 1.9 1 0 0 1 1 1 1 Ima1 N-terminal domain PyrI_C PF02748.10 EEB08342.1 - 0.025 14.0 1.3 0.4 10.1 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Sec23_Sec24 PF04810.10 EEB08342.1 - 0.098 12.2 5.8 0.05 13.1 0.8 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-CHY PF05495.7 EEB08342.1 - 5.2 7.3 11.4 3.3 7.9 0.6 3.9 3 1 0 4 4 4 0 CHY zinc finger adh_short PF00106.20 EEB08343.1 - 1.5e-30 106.3 0.1 1.9e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB08343.1 - 5.6e-14 52.2 0.0 7.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB08343.1 - 2.3e-11 43.9 0.1 2.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEB08343.1 - 1.6e-05 24.0 2.1 8.3e-05 21.6 1.4 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEB08343.1 - 6.3e-05 22.6 0.5 0.00014 21.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEB08343.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pex24p PF06398.6 EEB08344.1 - 2.9e-13 49.3 13.5 1.2e-07 30.8 3.9 3.0 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin Lectin_N PF03954.9 EEB08344.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Aldo_ket_red PF00248.16 EEB08345.1 - 3e-06 26.2 0.0 4.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fasciclin PF02469.17 EEB08345.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 0 Fasciclin domain AAA_11 PF13086.1 EEB08346.1 - 1.4e-62 211.3 0.0 7.1e-61 205.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_12 PF13087.1 EEB08346.1 - 1.2e-56 191.2 0.1 2.4e-56 190.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB08346.1 - 8.5e-14 51.0 0.8 6.3e-12 45.0 0.1 2.9 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEB08346.1 - 7.8e-13 48.4 0.0 2.7e-11 43.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EEB08346.1 - 1.4e-09 37.8 1.3 0.0056 16.2 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EEB08346.1 - 8.5e-06 25.7 0.0 4.9e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEB08346.1 - 3e-05 23.1 0.4 0.00041 19.4 0.3 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.1 EEB08346.1 - 5.8e-05 22.7 3.9 0.19 11.1 0.1 3.3 1 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EEB08346.1 - 7.9e-05 22.7 1.1 0.0028 17.6 0.0 3.0 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EEB08346.1 - 0.00014 21.9 0.2 0.0027 17.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EEB08346.1 - 0.00039 20.1 0.0 0.27 10.8 0.0 2.6 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.16 EEB08346.1 - 0.0015 17.9 0.0 0.011 15.0 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EEB08346.1 - 0.0019 18.2 0.3 0.0095 16.0 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EEB08346.1 - 0.0032 16.4 0.1 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Zot PF05707.7 EEB08346.1 - 0.0036 16.7 0.0 0.59 9.5 0.0 3.0 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA PF00004.24 EEB08346.1 - 0.0072 16.5 0.5 0.04 14.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 EEB08346.1 - 0.02 14.6 0.1 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_25 PF13481.1 EEB08346.1 - 0.022 14.1 0.1 0.21 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEB08346.1 - 0.026 13.9 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 EEB08346.1 - 0.028 13.6 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.4 EEB08346.1 - 0.033 12.8 0.0 0.06 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EEB08346.1 - 0.037 13.4 0.0 0.45 9.8 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EEB08346.1 - 0.046 14.5 0.1 0.25 12.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EEB08346.1 - 0.059 12.7 0.6 0.34 10.2 0.4 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EEB08346.1 - 0.09 12.6 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain TK PF00265.13 EEB08346.1 - 0.092 12.3 0.0 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Thymidine kinase AAA_23 PF13476.1 EEB08346.1 - 3.5 7.9 6.1 15 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EEB08347.2 - 1.7e-127 419.8 0.0 4.6e-21 74.9 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EEB08347.2 - 2.8e-30 105.2 0.7 0.0021 18.2 0.0 7.9 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EEB08347.2 - 5.5e-29 100.4 0.0 1.2e-09 37.8 0.0 8.2 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB08347.2 - 1.3e-25 90.4 1.3 0.0001 22.3 0.0 7.2 6 0 0 6 6 6 4 AAA ATPase domain AAA_17 PF13207.1 EEB08347.2 - 5.8e-22 78.7 0.1 0.011 16.5 0.0 7.5 6 0 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.1 EEB08347.2 - 6.2e-21 74.8 0.7 0.00066 19.7 0.0 8.0 8 0 0 8 8 7 3 Sigma-54 interaction domain AAA_14 PF13173.1 EEB08347.2 - 6.6e-21 74.5 0.0 0.00011 22.0 0.0 8.2 6 1 0 6 6 6 3 AAA domain AAA_22 PF13401.1 EEB08347.2 - 1e-19 70.9 4.3 0.0044 17.1 0.0 8.1 6 1 0 6 6 6 4 AAA domain AAA_33 PF13671.1 EEB08347.2 - 3.6e-19 69.0 0.0 0.027 14.3 0.0 7.1 6 0 0 6 6 6 5 AAA domain T2SE PF00437.15 EEB08347.2 - 7.1e-19 67.7 0.4 0.001 18.0 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein Sigma54_activat PF00158.21 EEB08347.2 - 9.3e-15 54.5 0.1 0.45 9.9 0.0 6.8 6 0 0 6 6 6 4 Sigma-54 interaction domain Zeta_toxin PF06414.7 EEB08347.2 - 1.9e-14 53.2 2.6 0.16 11.0 0.0 7.7 7 0 0 7 7 7 4 Zeta toxin AAA_18 PF13238.1 EEB08347.2 - 8.5e-14 51.9 19.8 0.0032 17.7 0.0 7.1 8 0 0 8 8 5 4 AAA domain ABC_tran PF00005.22 EEB08347.2 - 2.3e-13 50.6 2.5 0.061 13.6 0.0 6.6 6 0 0 6 6 5 3 ABC transporter AAA_19 PF13245.1 EEB08347.2 - 5.7e-13 48.4 5.5 0.14 11.9 0.0 6.4 6 0 0 6 6 6 4 Part of AAA domain RuvB_N PF05496.7 EEB08347.2 - 1.3e-10 40.6 3.3 0.019 14.0 0.0 7.1 7 0 0 7 7 7 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EEB08347.2 - 1.5e-10 40.6 1.7 7.3 5.6 0.0 8.9 9 1 1 10 10 10 0 Magnesium chelatase, subunit ChlI Miro PF08477.8 EEB08347.2 - 5.5e-10 39.7 2.3 4.8 7.6 0.0 6.8 6 0 0 6 6 6 0 Miro-like protein AAA_29 PF13555.1 EEB08347.2 - 6.7e-10 38.3 0.8 1.4 8.4 0.0 5.9 6 0 0 6 6 6 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEB08347.2 - 7.1e-10 39.0 4.2 0.43 10.7 0.0 7.4 7 0 0 7 7 7 1 RNA helicase UPF0079 PF02367.12 EEB08347.2 - 7.8e-10 38.4 4.5 0.31 10.6 0.0 6.3 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EEB08347.2 - 1.1e-09 38.0 2.2 1.6 8.4 0.0 6.4 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEB08347.2 - 2.3e-09 36.6 4.8 1.3 8.1 0.2 6.0 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEB08347.2 - 2.3e-09 36.9 0.6 0.37 10.1 0.0 5.9 6 0 0 6 6 5 2 AAA domain IstB_IS21 PF01695.12 EEB08347.2 - 2.5e-09 36.8 0.1 4.4 6.6 0.0 5.8 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_28 PF13521.1 EEB08347.2 - 7.1e-08 32.5 10.0 2.6 7.9 0.0 6.7 6 0 0 6 6 6 2 AAA domain PduV-EutP PF10662.4 EEB08347.2 - 8.8e-08 31.7 6.6 0.088 12.2 0.0 5.5 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EEB08347.2 - 1e-07 31.7 10.5 1.9 8.0 0.0 6.3 5 0 0 5 5 5 2 NACHT domain SRP54 PF00448.17 EEB08347.2 - 1.1e-06 28.2 6.2 0.35 10.3 0.2 5.8 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PhoH PF02562.11 EEB08347.2 - 1.1e-05 24.7 0.4 1.4 8.1 0.0 5.1 5 0 0 5 5 5 1 PhoH-like protein DUF927 PF06048.6 EEB08347.2 - 3e-05 23.4 0.5 0.43 9.7 0.3 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF927) MMR_HSR1 PF01926.18 EEB08347.2 - 0.00024 21.0 1.5 8.7 6.3 0.0 5.5 5 0 0 5 5 5 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEB08347.2 - 0.0011 18.5 0.6 2.1 7.7 0.0 3.9 4 0 0 4 4 3 1 FtsK/SpoIIIE family cobW PF02492.14 EEB08347.2 - 0.0031 16.9 5.6 2.1 7.7 0.0 5.1 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain AAA_6 PF12774.2 EEB08347.2 - 0.0038 16.7 0.0 5.2 6.5 0.0 5.0 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 CbiA PF01656.18 EEB08347.2 - 0.0079 15.6 2.0 0.9 8.9 0.0 3.9 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EEB08347.2 - 0.029 14.7 0.0 0.029 14.7 0.0 9.5 8 1 0 8 8 6 0 AAA domain NTPase_1 PF03266.10 EEB08347.2 - 0.034 13.8 11.9 19 4.9 0.1 6.1 6 0 0 6 6 6 0 NTPase DBI_PRT PF02277.12 EEB08347.2 - 0.42 9.6 0.4 18 4.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribosyltransferase ABC_membrane PF00664.18 EEB08348.2 - 8.2e-32 110.6 8.2 8.2e-32 110.6 5.7 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEB08348.2 - 6.4e-22 78.3 0.0 1.4e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EEB08348.2 - 1.2e-08 34.4 0.1 2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EEB08348.2 - 0.052 13.4 0.2 0.51 10.2 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RRM_6 PF14259.1 EEB08349.2 - 1.5e-25 88.9 0.8 4.3e-10 39.4 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB08349.2 - 5.1e-24 83.7 0.6 5.3e-12 45.1 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08349.2 - 1.7e-15 56.5 0.8 4.2e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08349.2 - 0.022 14.5 1.7 2.8 7.7 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EEB08349.2 - 0.092 12.3 1.3 36 3.8 0.0 3.1 2 1 1 3 3 3 0 Calcipressin Sec1 PF00995.18 EEB08350.2 - 3.2e-149 498.1 2.1 3.7e-149 497.9 1.5 1.0 1 0 0 1 1 1 1 Sec1 family UAE_UbL PF14732.1 EEB08350.2 - 0.046 13.8 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Med26 PF08711.6 EEB08351.2 - 0.052 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Pkinase PF00069.20 EEB08352.1 - 2.1e-74 249.9 0.0 3.6e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08352.1 - 2.9e-39 134.6 0.0 5.7e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EEB08352.1 - 1.1e-11 44.6 1.6 2.5e-11 43.5 0.8 1.9 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EEB08352.1 - 4.4e-09 35.7 0.0 6.2e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YukC PF10140.4 EEB08352.1 - 0.0041 15.7 0.1 0.0041 15.7 0.1 1.5 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EEB08352.1 - 0.0068 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3791 PF12668.2 EEB08352.1 - 0.0098 15.4 0.2 0.038 13.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3791) APH PF01636.18 EEB08352.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tom7 PF08038.7 EEB08353.1 - 1.2e-17 63.0 1.0 1.4e-17 62.8 0.7 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 EEB08354.2 - 4.3e-47 157.7 4.3 2e-17 62.6 0.1 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein HEAT PF02985.17 EEB08355.2 - 0.0031 17.4 0.5 16 5.8 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat DUF1640 PF07798.6 EEB08356.1 - 2.3e-21 76.6 4.7 3.6e-21 75.9 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phosphodiest PF01663.17 EEB08357.1 - 2e-16 60.3 0.4 2.8e-16 59.8 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EEB08357.1 - 8.1e-08 31.9 1.1 1.4e-07 31.1 0.7 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EEB08357.1 - 0.0065 15.6 0.2 0.014 14.6 0.1 1.5 1 0 0 1 1 1 1 Sulfatase CRT10 PF08728.5 EEB08358.2 - 1.8e-13 49.4 5.4 3.9e-06 25.1 0.7 2.8 1 1 0 2 2 2 2 CRT10 WD40 PF00400.27 EEB08358.2 - 9.5e-07 28.4 0.9 9.5e-07 28.4 0.6 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3402 PF11882.3 EEB08359.2 - 7.7e-44 150.3 8.6 1.1e-43 149.9 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) FA_hydroxylase PF04116.8 EEB08360.1 - 4.9e-12 46.2 20.4 4.9e-12 46.2 14.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TatC PF00902.13 EEB08360.1 - 1.5 8.1 8.6 2.8 7.3 2.1 2.5 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) UPF0220 PF05255.6 EEB08362.2 - 2.4e-53 179.7 4.9 2.9e-53 179.5 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 EEB08362.2 - 0.38 9.9 3.3 2.2 7.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pkinase PF00069.20 EEB08363.1 - 7.5e-64 215.3 0.0 8.9e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08363.1 - 4.5e-25 88.1 0.1 7.9e-25 87.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB08363.1 - 2.2e-05 24.3 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB08363.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EEB08363.1 - 0.0046 16.5 0.1 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EEB08363.1 - 0.033 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EEB08363.1 - 0.075 11.6 0.3 0.84 8.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Porin_3 PF01459.17 EEB08364.1 - 2e-80 270.0 0.0 2.3e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CorA PF01544.13 EEB08365.1 - 3.1e-44 151.1 0.0 4.3e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF485 PF04341.7 EEB08365.1 - 0.2 11.3 0.6 0.38 10.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 CBP4 PF07960.6 EEB08366.1 - 5.2e-15 55.2 0.1 5.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 CBP4 ATP-synt_E PF05680.7 EEB08366.1 - 0.00064 19.6 0.5 0.00075 19.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF4574 PF15141.1 EEB08366.1 - 0.046 13.4 0.1 0.061 13.0 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4574) Aminotran_5 PF00266.14 EEB08366.1 - 0.13 10.9 0.2 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 Aminotransferase class-V YtxH PF12732.2 EEB08366.1 - 7.5 6.9 8.1 48 4.4 5.6 2.0 1 1 0 1 1 1 0 YtxH-like protein GPI-anchored PF10342.4 EEB08368.1 - 1.2e-16 60.9 4.1 1.2e-16 60.9 2.9 3.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 EEB08368.1 - 0.51 9.6 16.3 0.62 9.4 11.3 1.1 1 0 0 1 1 1 0 Vta1 like ubiquitin PF00240.18 EEB08370.1 - 3e-12 45.7 0.1 6e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEB08370.1 - 0.036 13.7 0.2 0.074 12.7 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EEB08370.1 - 0.06 13.2 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 EEB08371.1 - 5.1e-76 254.4 0.0 4e-75 251.5 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 EEB08371.1 - 0.029 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Cyclin_N PF00134.18 EEB08372.1 - 7e-21 74.1 0.0 1.6e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB08372.1 - 2.3e-07 30.7 0.0 6.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain RecO_C PF02565.10 EEB08372.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O C terminal HSBP1 PF06825.7 EEB08374.1 - 0.0033 16.9 1.1 0.0035 16.8 0.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Translin PF01997.11 EEB08374.1 - 0.015 14.9 0.1 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Translin family Baculo_PEP_C PF04513.7 EEB08374.1 - 0.043 13.6 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cation_efflux PF01545.16 EEB08375.1 - 2.7e-21 75.8 7.0 3.6e-21 75.4 4.8 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4395 PF14340.1 EEB08375.1 - 2.8 8.0 7.5 0.81 9.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Pkinase PF00069.20 EEB08376.1 - 8.1e-47 159.5 0.0 1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08376.1 - 2.1e-25 89.2 0.0 2.8e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB08376.1 - 2.9e-05 23.9 2.4 0.0065 16.2 0.0 3.3 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB08376.1 - 3.8e-05 22.7 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB08376.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sterol_MT_C PF08498.5 EEB08377.1 - 1.1e-26 92.5 1.2 1.7e-26 91.9 0.8 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EEB08377.1 - 1.1e-22 80.2 0.0 2.8e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB08377.1 - 3.7e-16 59.2 0.0 5.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB08377.1 - 1.1e-14 54.3 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08377.1 - 3e-12 46.7 0.0 6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08377.1 - 5.4e-10 39.6 0.0 1.6e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEB08377.1 - 1e-09 37.9 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEB08377.1 - 2.3e-09 37.7 0.0 1.1e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EEB08377.1 - 1e-08 34.5 0.0 1.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EEB08377.1 - 6.6e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEB08377.1 - 1.9e-06 27.3 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EEB08377.1 - 0.0027 17.3 0.0 0.024 14.2 0.0 2.0 1 1 1 2 2 2 1 Hypothetical methyltransferase CDC48_2 PF02933.12 EEB08377.1 - 0.0084 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Methyltransf_15 PF09445.5 EEB08377.1 - 0.015 14.8 0.1 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EEB08377.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EEB08377.1 - 0.034 13.6 0.1 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EEB08377.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BolA PF01722.13 EEB08378.1 - 1.9e-25 88.6 0.3 3.7e-25 87.6 0.1 1.5 1 1 1 2 2 2 2 BolA-like protein HA2 PF04408.18 EEB08379.1 - 1.5e-14 53.8 0.0 1.5e-14 53.8 0.0 3.1 4 0 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEB08379.1 - 5.6e-13 48.7 0.0 1.7e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEB08379.1 - 1.2e-10 41.0 0.1 4.2e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08379.1 - 9.8e-09 34.9 0.3 4.5e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB08379.1 - 2.7e-07 30.8 0.1 1.1e-06 28.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain RWD PF05773.17 EEB08379.1 - 0.0001 22.1 1.0 0.00033 20.5 0.7 1.9 1 0 0 1 1 1 1 RWD domain T2SE PF00437.15 EEB08379.1 - 0.0021 17.0 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EEB08379.1 - 0.0039 16.7 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain KaiC PF06745.8 EEB08379.1 - 0.012 14.7 0.0 0.034 13.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EEB08379.1 - 0.015 15.1 0.0 0.13 12.2 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEB08379.1 - 0.022 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EEB08379.1 - 0.051 13.9 0.0 0.051 13.9 0.0 3.8 4 2 0 4 4 3 0 AAA domain AAA_16 PF13191.1 EEB08379.1 - 0.083 12.8 0.0 0.39 10.6 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain dsrm PF00035.20 EEB08379.1 - 0.7 10.5 5.1 12 6.5 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif ABC_tran PF00005.22 EEB08380.1 - 2.2e-40 138.1 8.9 1.3e-20 74.1 0.0 3.6 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 EEB08380.1 - 1e-16 61.7 16.7 1.1e-05 25.5 0.0 5.3 3 2 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EEB08380.1 - 2.1e-09 36.7 0.0 0.00077 18.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_2 PF12848.2 EEB08380.1 - 4.2e-09 36.1 5.2 4.2e-09 36.1 3.6 4.6 3 1 1 4 4 2 1 ABC transporter SMC_N PF02463.14 EEB08380.1 - 6.1e-07 28.9 19.3 0.009 15.2 0.1 5.2 6 0 0 6 6 5 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EEB08380.1 - 2.6e-06 27.5 1.2 0.024 14.7 0.0 3.8 3 2 0 3 3 3 1 AAA domain DUF258 PF03193.11 EEB08380.1 - 4.5e-06 25.9 0.0 0.00027 20.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EEB08380.1 - 7e-05 22.5 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EEB08380.1 - 0.0001 22.3 0.7 0.018 15.0 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EEB08380.1 - 0.00012 22.4 7.7 0.0023 18.2 2.4 5.2 4 2 0 4 4 3 2 AAA domain AAA_33 PF13671.1 EEB08380.1 - 0.00015 21.6 0.0 0.059 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEB08380.1 - 0.00017 21.0 0.2 0.85 8.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EEB08380.1 - 0.0002 21.0 0.0 0.04 13.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EEB08380.1 - 0.00021 21.7 0.6 1.1 9.7 0.0 3.5 4 0 0 4 4 2 2 Miro-like protein NACHT PF05729.7 EEB08380.1 - 0.00021 20.9 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 1 NACHT domain SbcCD_C PF13558.1 EEB08380.1 - 0.00068 19.4 1.0 0.64 9.9 0.0 3.6 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EEB08380.1 - 0.00071 19.5 0.0 0.033 14.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEB08380.1 - 0.00071 19.1 0.0 0.041 13.3 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EEB08380.1 - 0.001 18.5 5.6 0.65 9.3 0.0 4.2 4 1 0 4 4 4 2 AAA-like domain AAA PF00004.24 EEB08380.1 - 0.0011 19.1 3.8 0.13 12.5 0.0 4.2 4 2 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EEB08380.1 - 0.0014 18.0 2.1 0.031 13.7 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EEB08380.1 - 0.0018 18.1 0.1 1.9 8.4 0.0 3.5 3 1 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EEB08380.1 - 0.0059 16.3 0.2 0.42 10.3 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.1 EEB08380.1 - 0.0084 16.0 1.5 0.35 10.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_5 PF07728.9 EEB08380.1 - 0.012 15.3 0.0 1.5 8.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEB08380.1 - 0.062 14.1 0.0 0.062 14.1 0.0 5.0 4 1 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 EEB08380.1 - 0.079 13.1 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EEB08380.1 - 0.37 11.1 0.0 0.37 11.1 0.0 5.0 5 1 0 5 5 4 0 AAA domain ArgK PF03308.11 EEB08380.1 - 3.8 6.2 7.9 32 3.1 0.0 3.6 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 EEB08380.1 - 4.5 7.0 18.5 5.9 6.6 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function DUF87 PRKCSH-like PF12999.2 EEB08381.1 - 3.8e-78 261.0 8.1 3.8e-78 261.0 5.6 2.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EEB08381.1 - 1.8e-69 232.1 0.6 4.1e-69 230.9 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EEB08381.1 - 0.00017 21.4 13.8 0.028 14.3 1.2 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF536 PF04394.9 EEB08381.1 - 0.034 13.8 0.4 0.034 13.8 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF536 RAMPs PF03787.10 EEB08381.1 - 0.052 13.3 0.3 0.084 12.7 0.2 1.2 1 0 0 1 1 1 0 RAMP superfamily DUF948 PF06103.6 EEB08381.1 - 0.093 12.5 0.1 0.093 12.5 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.14 EEB08382.1 - 3e-18 65.2 2.4 3e-18 65.2 1.6 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEB08382.1 - 1.6e-14 53.9 13.2 5.9e-14 52.0 5.1 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EEB08382.1 - 0.0069 15.9 2.0 0.0069 15.9 1.4 2.3 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Vac_Fusion PF02346.11 EEB08382.1 - 0.0069 15.7 3.3 0.29 10.5 0.0 2.9 3 0 0 3 3 3 1 Chordopoxvirus fusion protein DUF4094 PF13334.1 EEB08382.1 - 0.0077 16.5 4.9 0.014 15.7 0.1 3.1 1 1 1 3 3 3 1 Domain of unknown function (DUF4094) Vps51 PF08700.6 EEB08382.1 - 0.013 15.2 2.4 0.14 11.9 0.0 3.2 2 1 1 3 3 3 0 Vps51/Vps67 DUF1634 PF07843.6 EEB08382.1 - 0.021 14.4 0.2 0.047 13.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) NPV_P10 PF05531.7 EEB08382.1 - 0.045 14.0 8.5 0.31 11.3 1.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V-SNARE PF05008.10 EEB08382.1 - 0.045 13.9 0.4 0.045 13.9 0.3 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3510 PF12022.3 EEB08382.1 - 0.064 13.3 0.3 0.064 13.3 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) BLOC1_2 PF10046.4 EEB08382.1 - 0.073 13.2 7.6 2.3 8.3 0.1 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 His_Phos_2 PF00328.17 EEB08382.1 - 0.08 12.2 2.8 0.1 11.8 2.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_13 PF13166.1 EEB08382.1 - 0.12 10.7 14.1 0.027 12.9 3.3 2.1 1 1 0 2 2 2 0 AAA domain Allexi_40kDa PF05549.6 EEB08382.1 - 0.24 10.6 9.5 0.061 12.6 2.4 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1515 PF07439.6 EEB08382.1 - 1.1 9.0 11.3 0.7 9.7 0.6 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) DUF3753 PF12575.3 EEB08382.1 - 1.9 8.3 4.5 2.1 8.2 0.5 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF3753) DUF3732 PF12532.3 EEB08382.1 - 2.9 7.3 10.9 0.18 11.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3732) Med28 PF11594.3 EEB08382.1 - 3.5 7.9 9.6 8.6 6.6 4.0 2.7 1 1 2 3 3 3 0 Mediator complex subunit 28 DUF4404 PF14357.1 EEB08382.1 - 3.6 8.0 13.2 2.1 8.8 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Med4 PF10018.4 EEB08382.1 - 4.4 6.6 11.3 0.11 11.8 0.3 2.8 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Med9 PF07544.8 EEB08382.1 - 4.6 7.0 8.4 6 6.6 0.3 3.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Acetyltransf_1 PF00583.19 EEB08383.1 - 3.1e-11 43.1 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB08383.1 - 8.1e-10 38.7 0.4 1.5e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEB08383.1 - 1.3e-05 25.1 0.7 2.3e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB08383.1 - 0.0018 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEB08383.1 - 0.017 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 EEB08384.1 - 1.1e-33 116.2 2.6 2.1e-33 115.3 1.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB08384.1 - 4.2e-07 29.7 15.3 1e-06 28.5 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOB1_Zn_bind PF08772.6 EEB08385.1 - 1.3e-29 101.7 3.3 3.6e-29 100.4 2.3 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EEB08385.1 - 8.1e-06 25.6 9.8 2.8e-05 23.9 6.8 2.0 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator BTV_NS2 PF04514.7 EEB08385.1 - 0.018 13.9 1.5 0.03 13.2 1.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Toxin_5 PF05294.8 EEB08385.1 - 5.4 7.3 7.0 2.9 8.1 2.4 2.1 2 0 0 2 2 2 0 Scorpion short toxin CLASP_N PF12348.3 EEB08386.1 - 2.2e-09 36.9 0.2 1e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 EEB08386.1 - 2.4e-08 33.3 1.1 0.089 12.9 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 EEB08386.1 - 1.3e-06 28.5 0.0 0.01 16.1 0.0 4.4 2 2 2 4 4 4 2 HEAT repeats CDC37_C PF08564.5 EEB08386.1 - 0.0011 18.8 1.0 1.2 8.9 0.1 2.9 2 0 0 2 2 2 2 Cdc37 C terminal domain HEAT_EZ PF13513.1 EEB08386.1 - 0.0028 18.0 0.1 43 4.7 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat TBPIP PF07106.8 EEB08386.1 - 0.026 14.0 12.4 0.04 13.4 3.4 3.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 EEB08386.1 - 0.026 13.7 6.2 0.071 12.3 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF904 PF06005.7 EEB08386.1 - 0.18 12.0 10.6 6.8 7.0 4.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Arm PF00514.18 EEB08386.1 - 0.21 11.4 2.1 16 5.5 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3573 PF12097.3 EEB08386.1 - 0.51 8.8 0.9 0.95 8.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Phage_GP20 PF06810.6 EEB08386.1 - 0.8 9.1 8.4 0.056 12.8 1.9 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 FemAB PF02388.11 EEB08386.1 - 2.1 6.9 5.4 4.4 5.8 3.8 1.5 1 0 0 1 1 1 0 FemAB family Spc24 PF08286.6 EEB08386.1 - 6.3 6.5 8.6 18 5.0 2.3 2.9 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 Arrestin_N PF00339.24 EEB08387.1 - 1.2e-05 25.1 0.1 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EEB08387.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Histone PF00125.19 EEB08388.1 - 7.3e-16 58.0 0.3 8.8e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB08388.1 - 3.3e-06 27.0 0.1 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EEB08388.1 - 2.5e-05 24.1 0.1 3.5e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEB08388.1 - 2.5e-05 24.3 0.1 3.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EEB08388.1 - 0.0049 16.1 0.0 0.0051 16.1 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EEB08388.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EEB08388.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EEB08389.1 - 7.7e-32 109.2 0.1 1.2e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEB08389.1 - 4e-06 26.9 0.0 6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEB08389.1 - 0.0088 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEB08389.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Sfi1 PF08457.5 EEB08390.1 - 1.4e-61 208.6 92.1 1.8e-60 204.9 57.3 2.5 1 1 2 3 3 3 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 EEB08391.1 - 1.5e-227 756.4 0.7 5.4e-227 754.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEB08391.1 - 1.1e-27 96.6 0.0 3e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEB08391.1 - 6.6e-20 71.1 2.2 1.5e-07 30.3 0.1 4.1 2 2 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EEB08391.1 - 0.045 12.8 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EEB08391.1 - 0.071 12.4 0.1 0.29 10.4 0.1 2.0 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-TFIIIC PF12660.2 EEB08392.1 - 9.7e-26 89.5 2.0 2.3e-25 88.3 1.4 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 EEB08392.1 - 6.6e-06 25.9 5.4 1.5e-05 24.7 0.9 3.1 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term PHF5 PF03660.9 EEB08392.1 - 0.15 12.0 3.5 0.09 12.8 0.6 2.0 2 0 0 2 2 2 0 PHF5-like protein RRM_5 PF13893.1 EEB08393.1 - 7.2e-10 38.5 0.1 1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB08393.1 - 9.1e-09 34.8 0.2 2.3e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08393.1 - 0.0019 18.1 0.1 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEB08393.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 Methyltransf_31 PF13847.1 EEB08394.1 - 2.6e-13 49.8 0.6 2.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EEB08394.1 - 4.5e-12 45.7 0.2 4.5e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EEB08394.1 - 1.7e-11 44.6 0.2 1.1e-10 42.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB08394.1 - 7.2e-11 42.4 0.0 2.4e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB08394.1 - 1.1e-09 38.2 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08394.1 - 2.1e-08 34.4 0.4 3.3e-07 30.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEB08394.1 - 4.2e-08 32.7 0.1 8.6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEB08394.1 - 2.4e-06 27.3 0.3 1.9e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08394.1 - 6.5e-05 23.3 0.1 0.00043 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain zf-C2H2_2 PF12756.2 EEB08394.1 - 0.00017 21.6 0.9 0.00053 20.0 0.5 1.9 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_9 PF08003.6 EEB08394.1 - 0.00029 19.6 0.4 0.00066 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EEB08394.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EEB08394.1 - 0.0016 17.9 0.1 0.0037 16.7 0.1 1.6 1 1 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EEB08394.1 - 0.0021 17.6 0.1 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.14 EEB08394.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 EEB08394.1 - 0.011 15.2 0.4 0.027 14.0 0.1 2.0 2 1 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TehB PF03848.9 EEB08394.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EEB08394.1 - 0.075 12.7 0.6 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain zf-Di19 PF05605.7 EEB08394.1 - 0.093 12.8 0.4 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EEB08394.1 - 0.12 12.8 2.1 0.16 12.3 0.2 2.2 2 0 0 2 2 1 0 C2H2-type zinc finger Cons_hypoth95 PF03602.10 EEB08394.1 - 0.15 11.4 0.5 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Prefoldin_2 PF01920.15 EEB08395.1 - 0.059 13.1 1.8 0.095 12.4 1.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit PTPlike_phytase PF14566.1 EEB08395.1 - 0.07 13.1 0.3 0.13 12.2 0.2 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate Transcrip_reg PF01709.15 EEB08396.1 - 9.6e-67 224.5 5.5 1.1e-66 224.3 3.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator SHQ1 PF04925.10 EEB08397.1 - 2.4e-63 213.0 1.4 3.8e-63 212.3 1.0 1.2 1 0 0 1 1 1 1 SHQ1 protein HSP20 PF00011.16 EEB08397.1 - 0.12 12.2 0.2 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 Hsp20/alpha crystallin family Syntaxin PF00804.20 EEB08398.1 - 1.8e-13 50.5 12.7 2e-13 50.4 5.2 2.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EEB08398.1 - 2e-13 49.8 0.6 2e-13 49.8 0.4 3.6 3 1 0 3 3 3 1 SNARE domain Sed5p PF11416.3 EEB08398.1 - 2.8e-08 33.0 1.1 7.4e-08 31.6 0.1 2.3 2 0 0 2 2 2 1 Integral membrane protein Sed5p Cluap1 PF10234.4 EEB08398.1 - 0.0027 16.9 5.2 0.0027 16.9 3.6 2.2 1 1 0 2 2 2 1 Clusterin-associated protein-1 Syntaxin-6_N PF09177.6 EEB08398.1 - 0.005 17.2 10.3 0.0084 16.4 1.6 3.1 2 1 1 3 3 3 1 Syntaxin 6, N-terminal DUF1664 PF07889.7 EEB08398.1 - 0.046 13.5 3.4 5.1 6.8 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-18_N PF10496.4 EEB08398.1 - 0.1 12.4 4.3 0.13 12.0 0.4 2.9 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.6 EEB08398.1 - 0.11 12.3 6.0 0.24 11.3 0.0 3.8 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EEB08398.1 - 0.14 12.3 8.1 0.47 10.6 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.4 EEB08398.1 - 0.14 12.1 5.8 0.69 9.8 1.9 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein AAA_13 PF13166.1 EEB08398.1 - 0.17 10.3 15.2 0.18 10.2 7.1 2.0 1 1 0 1 1 1 0 AAA domain LETM1 PF07766.8 EEB08398.1 - 0.48 9.4 3.7 0.39 9.7 0.7 2.0 2 0 0 2 2 2 0 LETM1-like protein Atg14 PF10186.4 EEB08398.1 - 2.3 7.1 12.4 1.4 7.8 6.3 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EEB08398.1 - 3.2 7.2 11.2 1.3 8.5 0.1 2.6 2 1 0 2 2 2 0 IncA protein T2SM PF04612.7 EEB08398.1 - 5.4 6.7 14.3 6.3 6.5 3.6 3.1 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein M HrpB7 PF09486.5 EEB08398.1 - 5.9 6.7 9.7 5.1 7.0 0.1 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Radical_SAM PF04055.16 EEB08399.2 - 2.2e-14 53.9 0.0 3.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Methyltrn_RNA_3 PF02598.12 EEB08400.1 - 1.2e-44 152.7 0.0 1.6e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Glyco_transf_34 PF05637.7 EEB08401.1 - 8.5e-65 218.5 0.0 1.1e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SMP_2 PF10144.4 EEB08401.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin AdoHcyase PF05221.12 EEB08402.1 - 1.2e-141 470.3 0.0 1.4e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EEB08402.1 - 5.4e-86 286.4 3.1 8.1e-86 285.8 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEB08402.1 - 2.2e-07 30.1 0.1 3.9e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EEB08402.1 - 2.8e-05 23.5 0.1 4.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EEB08402.1 - 0.05 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 EEB08402.1 - 0.05 13.1 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4448 PF14610.1 EEB08402.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pkinase PF00069.20 EEB08403.2 - 2.5e-58 197.2 0.0 4.3e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08403.2 - 3.6e-33 114.7 0.0 5.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEB08403.2 - 0.001 18.2 0.1 0.0023 17.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2642 PF10842.3 EEB08403.2 - 0.061 12.8 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) DUF1307 PF06998.6 EEB08403.2 - 0.11 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) WD40 PF00400.27 EEB08404.1 - 2.8e-14 52.3 15.6 9.8e-07 28.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat SRA1 PF07304.6 EEB08404.1 - 7e-07 29.1 0.6 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EEB08404.1 - 0.00059 19.6 0.3 0.0015 18.3 0.2 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EEB08404.1 - 0.012 15.4 0.4 0.08 12.7 0.0 2.4 2 1 0 2 2 2 0 Prp18 domain NIF PF03031.13 EEB08405.1 - 4.7e-42 143.3 0.0 8.1e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Thrombin_light PF09396.5 EEB08405.1 - 0.0054 16.3 0.2 0.053 13.1 0.2 2.3 2 0 0 2 2 2 1 Thrombin light chain APC10 PF03256.11 EEB08406.1 - 2.4e-61 206.7 0.0 2.7e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EEB08406.1 - 0.0065 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Iso_dh PF00180.15 EEB08407.1 - 3e-127 424.3 0.0 3.7e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mmp37 PF09139.6 EEB08408.1 - 1.4e-107 359.5 0.7 1.7e-107 359.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Blt1 PF12754.2 EEB08409.1 - 1.4e-98 330.3 20.1 1.7e-98 330.0 13.9 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component XhlA PF10779.4 EEB08409.1 - 0.16 11.9 2.5 0.28 11.1 0.8 2.3 1 1 1 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.16 EEB08409.1 - 0.27 11.2 8.4 1.1 9.2 0.3 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF1843 PF08898.5 EEB08409.1 - 0.4 10.7 3.1 0.71 9.9 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) TMF_DNA_bd PF12329.3 EEB08409.1 - 0.6 9.9 13.3 0.46 10.3 2.4 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EEB08409.1 - 1.1 8.8 14.0 2.6 7.6 0.7 3.7 3 1 0 3 3 3 0 Septum formation initiator GAS PF13851.1 EEB08409.1 - 1.1 8.4 19.0 0.85 8.7 7.0 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 EEB08409.1 - 3.3 7.0 24.9 4.1 6.7 14.1 2.3 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.6 EEB08409.1 - 3.5 7.3 29.7 0.82 9.4 4.0 3.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EEB08409.1 - 3.8 7.3 24.0 1.5 8.6 1.0 3.8 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.1 EEB08409.1 - 4.1 7.0 0.0 4.1 7.0 0.0 3.8 2 1 2 4 4 3 0 Nucleoporin complex subunit 54 zf-ZPR1 PF03367.8 EEB08409.1 - 5.9 6.0 7.5 3.8 6.6 1.9 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DNA_topoisoIV PF00521.15 EEB08411.1 - 3.2e-126 421.6 0.1 5.3e-126 420.9 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EEB08411.1 - 7.8e-34 116.3 0.5 2.1e-33 114.9 0.4 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EEB08411.1 - 7.1e-14 51.5 0.0 2.9e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EEB08411.1 - 1.4e-09 37.6 0.0 5.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosom_S12_S23 PF00164.20 EEB08412.1 - 5.8e-40 135.5 0.6 6.9e-40 135.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 WD40 PF00400.27 EEB08413.1 - 1.6e-31 107.0 9.6 2.9e-09 36.4 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EEB08413.1 - 1.3e-29 102.0 14.6 2e-29 101.4 10.1 1.3 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EEB08413.1 - 2.4e-05 24.1 0.4 0.00017 21.3 0.2 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EEB08413.1 - 0.013 15.2 0.1 0.4 10.4 0.0 3.0 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Cpn60_TCP1 PF00118.19 EEB08414.1 - 5.1e-160 533.2 0.1 5.8e-160 533.0 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dict-STAT-coil PF09267.5 EEB08415.2 - 0.0035 17.5 2.3 0.0035 17.5 1.6 2.1 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil APG6 PF04111.7 EEB08415.2 - 0.04 12.9 0.3 0.04 12.9 0.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 YgbB PF02542.11 EEB08415.2 - 0.044 13.6 0.4 0.069 12.9 0.3 1.4 1 1 0 1 1 1 0 YgbB family Reo_sigmaC PF04582.7 EEB08415.2 - 0.05 12.7 4.6 0.058 12.5 3.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HbrB PF08539.6 EEB08415.2 - 0.14 11.9 1.1 0.24 11.2 0.4 1.6 1 1 0 1 1 1 0 HbrB-like Mnd1 PF03962.10 EEB08415.2 - 0.36 10.4 3.9 0.28 10.8 0.3 1.9 1 1 1 2 2 2 0 Mnd1 family Baculo_PEP_C PF04513.7 EEB08415.2 - 0.43 10.4 6.8 0.21 11.3 2.9 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TruD PF01142.13 EEB08416.1 - 9.5e-70 235.1 0.0 1.5e-68 231.2 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) Exonuc_VIII PF06630.6 EEB08416.1 - 0.04 13.2 0.7 0.08 12.2 0.5 1.4 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Med14 PF08638.6 EEB08417.1 - 9e-53 178.4 0.0 1.8e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkr1 PF08636.5 EEB08418.1 - 7.9e-24 83.5 4.5 9e-24 83.3 3.1 1.0 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.1 EEB08418.1 - 0.0016 17.8 1.0 0.002 17.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Herpes_UL45 PF05473.7 EEB08418.1 - 0.066 12.6 1.9 0.088 12.2 1.3 1.1 1 0 0 1 1 1 0 UL45 protein Complex1_LYR PF05347.10 EEB08419.1 - 3.9e-10 39.3 0.3 5.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEB08419.1 - 3.4e-08 33.5 0.2 8.3e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEB08419.1 - 7e-06 26.4 0.6 1.3e-05 25.6 0.4 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Cullin PF00888.17 EEB08420.1 - 5.3e-50 170.5 3.2 1.5e-49 169.0 1.1 2.3 2 1 0 2 2 2 1 Cullin family APC2 PF08672.6 EEB08420.1 - 6.2e-25 87.2 0.5 3.2e-24 84.9 0.0 2.5 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Flg_hook PF02120.11 EEB08420.1 - 0.053 13.1 0.2 0.58 9.8 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK TrbL PF04610.9 EEB08420.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein SWI-SNF_Ssr4 PF08549.5 EEB08421.2 - 1.3e-31 109.7 20.8 1.3e-31 109.7 14.4 3.5 1 1 0 2 2 2 1 Fungal domain of unknown function (DUF1750) TnpV PF14198.1 EEB08421.2 - 2.8 7.8 10.3 0.054 13.3 1.7 2.1 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Vir_act_alpha_C PF10400.4 EEB08421.2 - 5.2 7.4 13.6 0.99 9.8 2.8 2.9 2 1 0 2 2 2 0 Virulence activator alpha C-term Mito_carr PF00153.22 EEB08422.1 - 1.1e-53 178.9 0.0 1.7e-16 59.6 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb2_6 PF00562.23 EEB08423.1 - 3.5e-114 381.5 0.0 5.3e-114 380.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEB08423.1 - 2e-36 124.8 0.0 2.8e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EEB08423.1 - 2.4e-24 84.8 0.0 8.5e-24 83.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EEB08423.1 - 2.9e-22 79.0 0.0 4.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EEB08423.1 - 6.3e-22 77.2 0.0 1.5e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EEB08423.1 - 3.1e-16 59.4 0.2 1.3e-15 57.3 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EEB08423.1 - 0.00023 21.0 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-Sec23_Sec24 PF04810.10 EEB08423.1 - 1.9 8.1 5.9 1 8.9 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Actin PF00022.14 EEB08424.1 - 2.1e-128 428.1 0.0 2.4e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEB08424.1 - 6.9e-08 31.4 0.0 7.6e-05 21.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DAHP_synth_1 PF00793.15 EEB08425.1 - 1e-97 326.0 0.0 1.3e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RhoGEF PF00621.15 EEB08426.1 - 5.6e-31 107.8 0.0 9.5e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain MIF4G PF02854.14 EEB08428.1 - 1.6e-27 96.3 4.5 4.7e-27 94.7 1.0 2.5 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EEB08428.1 - 3.1e-25 88.0 0.1 8e-24 83.5 0.0 2.5 2 0 0 2 2 2 1 MA3 domain Ribosomal_S2 PF00318.15 EEB08429.1 - 5.3e-57 192.4 0.5 3.7e-56 189.6 0.4 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 tRNA-synt_2b PF00587.20 EEB08430.1 - 2.1e-41 141.3 0.1 4.6e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEB08430.1 - 1.7e-13 50.3 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_M20 PF01546.23 EEB08431.1 - 8.1e-27 93.9 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEB08431.1 - 2.5e-07 30.4 0.0 8.1e-07 28.7 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEB08431.1 - 0.00015 21.5 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 Glucan_synthase PF02364.10 EEB08432.1 - 0 1453.1 0.0 0 1452.2 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEB08432.1 - 2.4e-37 127.4 0.1 7.7e-37 125.7 0.1 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aconitase PF00330.15 EEB08433.2 - 9.8e-174 578.1 0.0 2.3e-173 576.9 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEB08433.2 - 2.4e-44 150.6 0.0 4.4e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CBS PF00571.23 EEB08434.1 - 4e-29 100.1 4.1 2.6e-06 27.0 0.0 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EEB08434.1 - 4.1e-09 35.9 0.0 9.1e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain AAA_22 PF13401.1 EEB08434.1 - 0.012 15.7 0.0 0.042 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Med9 PF07544.8 EEB08435.1 - 0.0099 15.5 1.4 0.012 15.2 1.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF3636 PF12331.3 EEB08435.1 - 0.065 12.8 0.1 0.082 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Imm11 PF15563.1 EEB08435.1 - 0.075 12.1 0.5 0.096 11.7 0.3 1.3 1 1 0 1 1 1 0 Immunity protein 11 Cyclin PF08613.6 EEB08436.1 - 3.3e-23 82.7 0.2 5.9e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin Pkinase PF00069.20 EEB08437.1 - 1.7e-62 210.9 0.0 2.7e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08437.1 - 9.7e-38 129.7 0.0 5.2e-25 88.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEB08437.1 - 1.1e-05 24.6 0.2 2.5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB08437.1 - 0.02 14.6 0.5 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family GrpE PF01025.14 EEB08437.1 - 0.36 10.3 5.9 0.8 9.2 4.1 1.5 1 0 0 1 1 1 0 GrpE Nup35_RRM PF05172.8 EEB08438.2 - 1.5e-25 88.9 0.2 6.1e-25 86.8 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EEB08438.2 - 1.6e-08 34.1 0.0 3.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EEB08438.2 - 0.01 15.6 0.0 0.04 13.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EEB08439.1 - 3.5e-77 259.8 0.0 5.3e-75 252.7 0.0 3.5 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EEB08439.1 - 0.00042 20.7 8.9 2.7 8.8 0.1 6.8 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08439.1 - 0.0046 17.5 2.2 30 5.4 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08439.1 - 0.09 13.1 3.4 0.16 12.3 0.1 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EEB08440.1 - 1.5e-107 359.9 27.8 1.8e-107 359.7 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB08440.1 - 1.4e-24 86.4 40.3 2.3e-24 85.7 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.23 EEB08441.2 - 6.5e-16 57.4 0.0 1.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB08441.2 - 4.5e-14 51.7 0.0 7.8e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EEB08441.2 - 1.7e-11 44.1 0.2 1.7e-11 44.1 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EEB08441.2 - 2.6e-11 42.8 0.0 4.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4298 PF14131.1 EEB08441.2 - 0.17 11.8 5.1 4.9 7.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Not1 PF04054.10 EEB08442.1 - 5e-111 371.2 9.5 7.7e-110 367.3 3.4 2.9 1 1 1 2 2 2 2 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EEB08442.1 - 2.3e-36 124.7 7.5 2.3e-36 124.7 5.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) ERG2_Sigma1R PF04622.7 EEB08443.1 - 1.2e-89 299.3 0.2 1.3e-89 299.1 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EMP24_GP25L PF01105.19 EEB08443.1 - 0.28 10.8 1.1 0.41 10.3 0.8 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sgf11 PF08209.6 EEB08444.2 - 1.6e-15 56.1 0.9 1.6e-15 56.1 0.6 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EEB08444.2 - 0.00031 20.3 0.5 0.00031 20.3 0.3 3.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type DUF2321 PF10083.4 EEB08444.2 - 0.038 13.4 0.9 0.047 13.1 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) C_tripleX PF02363.14 EEB08444.2 - 1.7 8.8 4.9 4.7 7.4 3.4 1.8 1 0 0 1 1 1 0 Cysteine rich repeat HypA PF01155.14 EEB08444.2 - 4.2 7.1 6.6 3.3 7.4 0.2 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EEB08444.2 - 5.6 7.0 11.5 3.4 7.6 1.7 2.8 2 1 1 3 3 3 0 Zinc ribbon domain RhoGEF PF00621.15 EEB08445.1 - 2.8e-13 50.1 5.0 2.6e-12 46.9 3.5 2.2 1 1 0 1 1 1 1 RhoGEF domain Pro_isomerase PF00160.16 EEB08446.1 - 1.2e-52 178.1 0.0 1.4e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EEB08447.1 - 3.2e-65 219.8 0.0 5.3e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08447.1 - 1.7e-32 112.4 0.0 3.1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08447.1 - 8.4e-09 34.7 0.0 2.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEB08447.1 - 7.1e-05 22.6 0.1 0.00092 19.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEB08447.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Toxin_37 PF11415.3 EEB08447.1 - 0.03 13.9 0.4 0.03 13.9 0.3 1.7 2 0 0 2 2 2 0 Antifungal peptide termicin HMG_box PF00505.14 EEB08448.1 - 3.7e-24 84.7 3.2 6.1e-24 84.0 2.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEB08448.1 - 6.7e-18 64.8 2.6 1.2e-17 64.0 1.8 1.4 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EEB08448.1 - 0.011 15.9 0.8 0.023 14.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) HMG_box_5 PF14887.1 EEB08448.1 - 0.021 14.6 0.6 0.021 14.6 0.4 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Abhydrolase_6 PF12697.2 EEB08449.1 - 2.8e-33 115.7 0.0 3.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB08449.1 - 1.2e-20 73.7 0.5 2.9e-20 72.5 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB08449.1 - 2.9e-15 56.4 0.0 6.1e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEB08449.1 - 2.7e-07 30.3 0.2 2.7e-07 30.3 0.2 2.4 3 0 0 3 3 3 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EEB08449.1 - 6e-06 25.9 0.1 6.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 EEB08449.1 - 1.3e-05 25.5 0.1 0.00012 22.3 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 EEB08449.1 - 0.00011 21.8 0.2 0.017 14.6 0.1 2.7 2 1 0 2 2 2 1 PGAP1-like protein DUF1100 PF06500.6 EEB08449.1 - 0.00016 20.4 0.0 0.00025 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.5 EEB08449.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF2305 PF10230.4 EEB08449.1 - 0.0064 15.9 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 EEB08449.1 - 0.0094 15.4 0.0 0.024 14.0 0.0 1.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EEB08449.1 - 0.024 13.8 0.2 0.069 12.3 0.2 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEB08449.1 - 0.05 13.0 2.6 8.6 5.7 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF915 PF06028.6 EEB08449.1 - 0.12 11.4 0.1 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Sugar_tr PF00083.19 EEB08451.1 - 1.3e-122 409.6 23.2 1.5e-122 409.4 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB08451.1 - 2.7e-22 78.9 28.0 2.6e-18 65.8 5.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEB08451.1 - 0.015 13.4 3.6 0.024 12.7 2.5 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Pox_A14 PF05767.7 EEB08451.1 - 0.098 12.6 0.8 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PRA1 PF03208.14 EEB08451.1 - 1.1 8.6 5.8 0.17 11.2 0.6 2.2 2 0 0 2 2 2 0 PRA1 family protein Sugar_tr PF00083.19 EEB08453.1 - 7.6e-112 374.1 21.5 8.9e-112 373.9 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB08453.1 - 5.1e-20 71.5 27.8 9.1e-15 54.2 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEB08453.1 - 0.016 13.3 6.1 0.023 12.8 4.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DAGAT PF03982.8 EEB08454.1 - 3.7e-74 249.0 0.1 3.7e-44 150.6 0.0 2.0 1 1 1 2 2 2 2 Diacylglycerol acyltransferase DUF2852 PF11014.3 EEB08454.1 - 0.28 11.1 3.5 0.52 10.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) RAMP4 PF06624.7 EEB08456.1 - 9.5e-05 21.8 0.2 0.00012 21.5 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 StbA PF06406.6 EEB08456.1 - 0.029 13.3 0.1 0.031 13.2 0.1 1.0 1 0 0 1 1 1 0 StbA protein DUF4366 PF14283.1 EEB08456.1 - 0.062 12.7 0.0 0.062 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3753 PF12575.3 EEB08456.1 - 0.11 12.2 0.2 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) LRR_4 PF12799.2 EEB08457.1 - 0.026 14.1 14.2 3.4 7.3 0.0 5.8 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEB08457.1 - 0.45 10.7 21.2 31 5.0 0.3 8.9 11 0 0 11 11 11 0 Leucine Rich repeat SNF2_N PF00176.18 EEB08458.1 - 5.2e-69 232.3 0.0 8.2e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB08458.1 - 1.6e-10 40.7 0.0 3.8e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EEB08458.1 - 3.1e-06 26.7 12.3 3.1e-06 26.7 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EEB08458.1 - 1.7e-05 24.7 0.1 8.5e-05 22.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EEB08458.1 - 0.00013 21.5 9.3 0.00013 21.5 6.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEB08458.1 - 0.00017 21.3 11.0 0.00017 21.3 7.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB08458.1 - 0.00091 19.1 11.7 0.00091 19.1 8.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB08458.1 - 0.0019 18.0 11.1 0.0019 18.0 7.7 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEB08458.1 - 0.0033 17.0 5.8 0.0099 15.5 4.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger IF-2B PF01008.12 EEB08459.1 - 4.3e-71 239.1 0.6 5e-71 238.9 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Prominin PF05478.6 EEB08459.1 - 0.054 11.0 0.0 0.072 10.6 0.0 1.1 1 0 0 1 1 1 0 Prominin zf-RING_2 PF13639.1 EEB08460.1 - 1.9e-10 40.4 11.5 1.9e-10 40.4 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB08460.1 - 1.2e-08 34.7 11.0 1.2e-08 34.7 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB08460.1 - 1.5e-08 34.1 6.7 1.5e-08 34.1 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB08460.1 - 3.2e-08 33.0 10.5 3.2e-08 33.0 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEB08460.1 - 2.5e-07 30.4 10.1 2.5e-07 30.4 7.0 2.9 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EEB08460.1 - 3.4e-06 26.6 10.5 3.4e-06 26.6 7.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEB08460.1 - 9.9e-05 21.9 5.7 0.00028 20.5 4.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EEB08460.1 - 0.00076 19.5 7.4 0.00076 19.5 5.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEB08460.1 - 0.001 18.8 1.2 0.0026 17.5 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EEB08460.1 - 0.0047 16.4 4.2 0.0087 15.5 2.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EEB08460.1 - 0.0095 15.7 14.7 0.6 9.9 0.5 3.3 2 1 1 3 3 3 1 Double zinc ribbon zinc-ribbons_6 PF07191.7 EEB08460.1 - 0.087 12.6 13.2 0.61 9.9 3.3 2.4 2 0 0 2 2 2 0 zinc-ribbons Rubredoxin PF00301.15 EEB08460.1 - 0.31 10.9 0.1 0.31 10.9 0.1 5.3 5 1 1 6 6 6 0 Rubredoxin Urm1 PF09138.6 EEB08461.1 - 3.9e-30 103.8 0.7 4.8e-30 103.5 0.5 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EEB08461.1 - 5.9e-07 29.8 0.1 7.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 ThiS family NurA PF09376.5 EEB08461.1 - 0.032 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 NurA domain RRP7 PF12923.2 EEB08462.1 - 1e-35 122.6 9.1 1.5e-35 122.0 6.3 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) THP2 PF09432.5 EEB08462.1 - 0.096 12.5 2.2 2.5 7.9 0.3 2.2 2 0 0 2 2 2 0 Tho complex subunit THP2 Occludin_ELL PF07303.8 EEB08462.1 - 0.17 12.6 5.0 0.49 11.1 0.1 2.5 2 0 0 2 2 2 0 Occludin homology domain MAT1 PF06391.8 EEB08463.2 - 2.9e-56 190.2 13.9 4.7e-56 189.5 9.6 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EEB08463.2 - 0.0055 16.3 8.4 0.028 14.0 5.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) VIT1 PF01988.14 EEB08463.2 - 0.018 14.5 0.3 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 VIT family zf-RING_2 PF13639.1 EEB08463.2 - 0.024 14.4 6.8 0.054 13.3 4.7 1.6 1 1 0 1 1 1 0 Ring finger domain DUF3797 PF12677.2 EEB08463.2 - 0.069 12.7 0.8 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-C3HC4_2 PF13923.1 EEB08463.2 - 0.14 12.2 9.5 0.48 10.4 6.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB08463.2 - 0.17 11.5 7.8 0.44 10.2 5.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB08463.2 - 0.46 10.2 9.2 3.8 7.3 6.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain AAA_23 PF13476.1 EEB08463.2 - 0.9 9.8 7.4 1.3 9.2 5.2 1.3 1 0 0 1 1 1 0 AAA domain IBR PF01485.16 EEB08463.2 - 6.8 6.6 7.8 4 7.3 1.5 2.5 1 1 1 2 2 2 0 IBR domain zf-RING_4 PF14570.1 EEB08463.2 - 7.2 6.2 11.1 27 4.4 7.2 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TLD PF07534.11 EEB08465.1 - 3.9e-22 78.7 1.2 4.3e-20 72.1 0.1 2.5 1 1 1 2 2 2 2 TLD DUF4298 PF14131.1 EEB08465.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) EVE PF01878.13 EEB08466.1 - 3.3e-44 150.3 0.0 5e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 EVE domain MAGUK_N_PEST PF10608.4 EEB08466.1 - 0.023 15.0 0.0 8.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK DUF2052 PF09747.4 EEB08466.1 - 0.099 12.5 2.8 0.16 11.8 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Coleoptericin PF06286.6 EEB08466.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Coleoptericin Med8 PF10232.4 EEB08467.2 - 3.3e-43 147.8 8.6 5e-43 147.2 5.8 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PilJ PF13675.1 EEB08467.2 - 0.22 11.8 3.6 1.5 9.1 0.4 2.3 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Kelch_6 PF13964.1 EEB08468.1 - 3.3e-20 71.3 3.4 8.1e-07 28.9 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EEB08468.1 - 5.5e-17 61.4 0.8 9.9e-07 28.7 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EEB08468.1 - 4e-15 55.0 3.4 0.00017 21.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EEB08468.1 - 7.6e-14 51.2 2.4 3.1e-05 23.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EEB08468.1 - 2.2e-12 46.5 1.4 1.4e-06 27.9 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EEB08468.1 - 8.9e-12 44.2 3.7 0.0011 18.6 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Ssu72 PF04722.8 EEB08469.1 - 2.5e-88 294.5 0.0 2.8e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF3857 PF12969.2 EEB08469.1 - 0.013 15.1 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) LMWPc PF01451.16 EEB08469.1 - 0.029 14.6 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase GIT_SHD PF08518.6 EEB08470.1 - 2.5e-14 52.3 7.4 1.6e-11 43.3 0.5 2.8 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT BCAS2 PF05700.6 EEB08470.1 - 0.055 12.9 24.4 0.13 11.7 2.5 2.7 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) V_ATPase_I PF01496.14 EEB08470.1 - 0.096 10.5 11.2 0.15 9.9 7.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 EEB08470.1 - 0.21 10.1 6.3 0.31 9.5 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CALCOCO1 PF07888.6 EEB08470.1 - 0.29 9.3 22.6 0.32 9.2 14.1 1.9 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like RPW8 PF05659.6 EEB08470.1 - 0.82 9.2 9.1 2.4 7.6 2.1 3.2 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IncA PF04156.9 EEB08470.1 - 1.8 8.1 26.1 12 5.3 18.1 2.3 1 1 0 1 1 1 0 IncA protein Nup54 PF13874.1 EEB08470.1 - 2.6 7.6 22.6 1.3 8.6 0.4 3.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 tRNA-synt_2d PF01409.15 EEB08471.1 - 9.1e-88 293.6 0.0 1.3e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EEB08471.1 - 4.7e-05 23.0 0.0 7.4e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EEB08471.1 - 8.4e-05 21.4 7.3 0.00016 20.5 0.0 3.5 3 1 0 4 4 4 1 tRNA synthetases class II (D, K and N) Hist_deacetyl PF00850.14 EEB08472.1 - 1.1e-82 277.8 0.2 1.4e-82 277.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EEB08473.1 - 1.1e-20 73.8 3.0 1.6e-20 73.3 2.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEB08473.1 - 6.6e-10 38.5 9.0 1e-09 37.8 6.3 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB08473.1 - 0.0021 17.3 2.4 0.005 16.1 1.7 1.7 1 0 0 1 1 1 1 PHD-finger Moricin PF06451.6 EEB08473.1 - 0.0048 16.3 0.3 0.011 15.2 0.2 1.5 1 0 0 1 1 1 1 Moricin Mic1 PF07035.7 EEB08473.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like zf-HC5HC2H PF13771.1 EEB08473.1 - 0.35 11.0 4.9 1.1 9.3 3.4 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain EIF_2_alpha PF07541.7 EEB08474.1 - 1.6e-41 140.5 0.2 7.5e-41 138.4 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EEB08474.1 - 9.8e-12 44.8 2.5 2.1e-11 43.7 1.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SET PF00856.23 EEB08475.1 - 6.9e-14 52.4 0.0 9.6e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 SET domain APH PF01636.18 EEB08475.1 - 0.031 14.0 0.2 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAF PF08666.7 EEB08475.1 - 0.12 12.8 0.0 18 5.8 0.0 2.3 2 0 0 2 2 2 0 SAF domain Metallophos PF00149.23 EEB08476.1 - 2.7e-40 137.9 3.1 4.1e-40 137.3 2.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAM_decarbox PF01536.11 EEB08477.1 - 4e-92 308.4 0.0 4.9e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase 60KD_IMP PF02096.15 EEB08478.1 - 3.5e-40 137.7 0.6 5.5e-40 137.1 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein STE3 PF02076.10 EEB08478.1 - 0.023 13.7 0.2 0.041 12.9 0.2 1.3 1 0 0 1 1 1 0 Pheromone A receptor Hid1 PF12722.2 EEB08479.1 - 2.7e-47 161.0 27.4 2.7e-47 161.0 19.0 1.8 1 1 0 2 2 2 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEB08479.1 - 2.7e-13 48.9 7.1 2.7e-13 48.9 4.9 2.2 2 1 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein PLU-1 PF08429.6 EEB08480.1 - 1.7e-72 244.1 10.2 2.9e-70 236.8 6.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein PHD PF00628.24 EEB08480.1 - 6.7e-26 89.7 40.8 3.7e-11 42.5 4.8 4.2 4 0 0 4 4 4 3 PHD-finger JmjC PF02373.17 EEB08480.1 - 2.1e-11 44.0 0.1 6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EEB08480.1 - 2.1e-06 27.4 0.1 1.3e-05 24.9 0.0 2.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain PHD_2 PF13831.1 EEB08480.1 - 0.035 13.4 30.7 0.016 14.5 0.6 4.0 4 0 0 4 4 4 0 PHD-finger zf-PHD-like PF15446.1 EEB08480.1 - 0.37 10.0 24.7 0.065 12.5 0.2 3.9 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain TFIIF_alpha PF05793.7 EEB08480.1 - 4 5.6 5.7 11 4.3 4.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L27 PF01016.14 EEB08481.1 - 2.8e-34 116.7 1.1 3.5e-34 116.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein MOR2-PAG1_N PF14222.1 EEB08482.1 - 3.2e-115 385.9 18.4 6.4e-114 381.6 12.8 2.5 1 1 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EEB08482.1 - 4.3e-48 164.3 5.6 1e-32 113.9 0.1 3.6 3 1 1 4 4 4 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EEB08482.1 - 2.5e-24 85.0 5.0 2.6e-09 35.2 0.0 3.1 3 0 0 3 3 3 3 Cell morphogenesis central region PC_rep PF01851.17 EEB08483.1 - 1.6e-27 94.1 21.7 6.6e-05 22.9 0.0 9.5 11 0 0 11 11 11 7 Proteasome/cyclosome repeat Gon7 PF08738.5 EEB08484.1 - 0.14 12.1 3.5 0.3 11.1 2.5 1.7 1 1 0 1 1 1 0 Gon7 family GCV_H PF01597.14 EEB08486.1 - 2.7e-45 153.0 0.5 3.6e-45 152.5 0.3 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EEB08486.1 - 0.00064 19.3 0.5 0.0015 18.1 0.2 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EEB08486.1 - 0.0011 18.6 0.3 0.0019 17.8 0.2 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Arrestin_C PF02752.17 EEB08487.1 - 6e-19 68.4 0.0 1.7e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEB08487.1 - 4.4e-11 42.8 0.0 3.8e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.19 EEB08488.1 - 1.4e-29 102.9 43.3 2.8e-21 75.6 8.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEB08488.1 - 1.3e-18 66.8 44.3 2.4e-16 59.4 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SRI PF08236.6 EEB08489.1 - 0.02 14.8 0.8 0.057 13.3 0.0 2.1 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Taxilin PF09728.4 EEB08489.1 - 0.057 12.5 0.2 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF3505 PF12013.3 EEB08489.1 - 0.15 12.3 1.7 0.23 11.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) Cellulase PF00150.13 EEB08490.1 - 1.9e-05 23.9 0.1 2.8e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HTH_21 PF13276.1 EEB08490.1 - 0.084 12.8 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 HTH-like domain zf-C2H2 PF00096.21 EEB08491.1 - 0.0011 19.1 1.7 0.0051 17.0 1.1 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB08491.1 - 0.053 13.8 2.3 0.23 11.8 1.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_S24 PF00717.18 EEB08492.1 - 2.1e-08 33.6 0.0 5.8e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEB08492.1 - 1e-06 28.3 0.0 0.00047 19.6 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Ribosomal_L4 PF00573.17 EEB08493.1 - 3.1e-44 150.6 0.0 3.5e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Mito_carr PF00153.22 EEB08494.1 - 5e-61 202.4 2.9 1.7e-20 72.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.11 EEB08494.1 - 0.056 13.0 0.1 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region F-box-like PF12937.2 EEB08495.1 - 8.8e-07 28.5 2.4 1.1e-06 28.3 0.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEB08495.1 - 1.5e-06 27.7 0.5 3.2e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EEB08495.1 - 0.0022 17.8 0.6 0.0043 16.8 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DNA_ligase_A_N PF04675.9 EEB08495.1 - 0.11 12.3 0.2 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 DNA ligase N terminus MFS_1 PF07690.11 EEB08496.1 - 3.8e-28 98.2 42.7 9.8e-25 86.9 18.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB08496.1 - 8.5e-12 44.3 11.0 8.5e-12 44.3 7.6 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter DUF3099 PF11298.3 EEB08496.1 - 0.0093 15.6 6.2 0.96 9.2 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3099) Pyr_redox_2 PF07992.9 EEB08497.1 - 5.1e-27 95.0 0.4 6.5e-27 94.7 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB08497.1 - 7.3e-18 64.7 0.4 7.7e-15 55.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB08497.1 - 1e-07 32.2 0.0 2.4e-05 24.5 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEB08497.1 - 5.7e-05 22.3 0.8 0.00081 18.5 0.1 2.4 2 1 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EEB08497.1 - 7.4e-05 22.9 0.0 0.019 15.2 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EEB08497.1 - 0.00023 20.3 0.2 0.093 11.7 0.0 2.7 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EEB08497.1 - 0.00028 20.8 0.5 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEB08497.1 - 0.00043 19.3 4.4 0.33 9.8 0.3 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EEB08497.1 - 0.0013 17.6 3.9 0.062 12.1 0.5 3.4 2 2 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EEB08497.1 - 0.0014 17.6 0.1 0.38 9.6 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EEB08497.1 - 0.0027 17.8 0.2 1 9.4 0.0 2.7 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EEB08497.1 - 0.012 15.3 0.1 4.4 7.0 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEB08497.1 - 0.019 13.4 0.7 0.065 11.7 0.3 2.0 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EEB08497.1 - 0.03 13.1 5.2 0.11 11.3 0.5 2.9 3 1 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.2 EEB08497.1 - 0.032 13.3 0.1 0.93 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.7 EEB08497.1 - 0.043 13.1 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Trp_halogenase PF04820.9 EEB08497.1 - 0.076 11.6 1.2 0.13 10.8 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 EEB08497.1 - 0.22 10.9 1.6 11 5.4 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Nop14 PF04147.7 EEB08498.1 - 3e-218 726.7 30.6 3.8e-218 726.4 21.2 1.1 1 0 0 1 1 1 1 Nop14-like family RhoGAP PF00620.22 EEB08499.1 - 9.4e-37 125.9 0.1 2.5e-36 124.5 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEB08499.1 - 5.2e-20 71.2 45.9 5.6e-13 48.7 4.2 5.3 5 0 0 5 5 5 2 LIM domain Alg6_Alg8 PF03155.10 EEB08500.1 - 3e-143 478.0 39.8 8.6e-143 476.5 27.6 1.6 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RINGv PF12906.2 EEB08501.1 - 1.2e-15 57.3 12.1 2.6e-15 56.1 8.4 1.7 1 0 0 1 1 1 1 RING-variant domain DUF1395 PF07160.7 EEB08501.1 - 0.00085 18.8 2.1 0.0018 17.8 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) Phage_Gp23 PF10669.4 EEB08501.1 - 0.043 13.9 0.1 0.043 13.9 0.1 2.7 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) zf-RING_2 PF13639.1 EEB08501.1 - 1.5 8.7 11.7 3.6 7.5 8.1 1.7 1 0 0 1 1 1 0 Ring finger domain ABC_tran PF00005.22 EEB08502.1 - 7.7e-33 113.6 0.0 2.2e-18 66.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EEB08502.1 - 4e-13 48.7 4.1 1.1e-12 47.3 2.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EEB08502.1 - 2.9e-11 43.8 8.1 0.022 14.7 0.0 4.2 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EEB08502.1 - 6.4e-11 41.8 1.3 0.0055 15.9 0.3 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EEB08502.1 - 2.5e-07 29.9 2.5 2.5e-07 29.9 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 EEB08502.1 - 3.6e-07 29.5 0.2 1.4 7.9 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EEB08502.1 - 2e-06 28.6 0.1 0.03 15.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEB08502.1 - 7.5e-06 26.1 0.0 0.003 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEB08502.1 - 1.4e-05 25.3 0.0 0.03 14.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EEB08502.1 - 2.5e-05 23.5 1.2 0.1 11.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEB08502.1 - 4.2e-05 22.9 0.7 0.14 11.6 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EEB08502.1 - 4.8e-05 23.0 2.1 4.8e-05 23.0 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 EEB08502.1 - 0.00021 21.6 0.0 0.59 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEB08502.1 - 0.00021 20.9 0.1 0.071 12.7 0.1 2.3 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EEB08502.1 - 0.00047 19.7 0.2 0.0062 16.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EEB08502.1 - 0.00047 20.5 0.3 0.13 12.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 EEB08502.1 - 0.00059 19.6 12.1 0.00064 19.4 1.6 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 EEB08502.1 - 0.00072 19.3 11.2 0.0014 18.4 7.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 EEB08502.1 - 0.00072 19.0 0.1 0.3 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EEB08502.1 - 0.0019 16.9 0.1 0.051 12.2 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_7 PF12838.2 EEB08502.1 - 0.0023 18.2 1.7 0.0023 18.2 1.2 2.5 1 1 0 2 2 2 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 EEB08502.1 - 0.0024 18.0 0.1 0.98 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 EEB08502.1 - 0.0026 17.2 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_10 PF13237.1 EEB08502.1 - 0.0034 17.1 1.4 0.0034 17.1 1.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_14 PF13173.1 EEB08502.1 - 0.0048 16.7 0.1 1.7 8.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EEB08502.1 - 0.0054 16.1 2.8 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EEB08502.1 - 0.0095 16.4 0.0 0.58 10.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Fer4_16 PF13484.1 EEB08502.1 - 0.0097 16.6 0.1 0.0097 16.6 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_33 PF13671.1 EEB08502.1 - 0.01 15.7 0.0 0.83 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEB08502.1 - 0.013 15.4 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EEB08502.1 - 0.015 14.9 1.8 1.5 8.5 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EEB08502.1 - 0.023 13.5 0.0 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_3 PF12798.2 EEB08502.1 - 0.023 15.2 4.0 0.023 15.2 2.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 EEB08502.1 - 0.032 14.8 1.0 0.099 13.2 0.7 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_8 PF13183.1 EEB08502.1 - 0.032 14.2 8.6 0.094 12.7 6.0 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEB08502.1 - 0.042 14.1 12.2 0.17 12.1 8.5 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EEB08502.1 - 0.048 13.2 1.5 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EEB08502.1 - 0.048 13.5 0.0 17 5.4 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EEB08502.1 - 0.065 13.1 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEB08502.1 - 0.088 11.9 0.1 0.23 10.5 0.0 1.7 1 0 0 1 1 1 0 KaiC Thymidylate_kin PF02223.12 EEB08502.1 - 0.14 11.5 0.1 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.9 EEB08502.1 - 0.15 11.8 0.1 9.1 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 EEB08502.1 - 0.2 10.0 0.0 0.2 10.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 EEB08502.1 - 0.35 10.5 1.6 28 4.3 0.0 2.8 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.4 EEB08502.1 - 0.37 10.2 2.6 0.44 10.0 0.0 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 EEB08502.1 - 0.38 11.2 14.2 0.091 13.1 1.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 EEB08502.1 - 4 7.8 11.4 0.18 12.1 0.9 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain S-AdoMet_synt_C PF02773.11 EEB08503.1 - 1.7e-73 244.8 0.1 2.8e-73 244.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EEB08503.1 - 2.4e-47 159.8 0.0 4.1e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EEB08503.1 - 5.4e-44 148.4 0.9 9e-44 147.7 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain PGK PF00162.14 EEB08504.1 - 1.4e-149 497.8 1.7 1.6e-149 497.6 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HEAT_EZ PF13513.1 EEB08505.1 - 2.2e-25 88.4 0.1 2.6e-06 27.7 0.0 9.9 10 0 0 10 10 10 3 HEAT-like repeat HEAT PF02985.17 EEB08505.1 - 2e-22 77.2 13.7 6.6e-06 25.7 0.0 11.6 14 0 0 14 14 12 5 HEAT repeat HEAT_2 PF13646.1 EEB08505.1 - 4.7e-16 58.8 8.0 7.2e-06 26.2 0.1 8.5 6 2 2 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EEB08505.1 - 3.6e-12 46.5 5.7 0.031 14.6 0.0 7.5 6 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EEB08505.1 - 6.1e-10 38.4 3.8 4.6e-07 28.9 0.0 4.9 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EEB08505.1 - 2.7e-09 36.8 4.4 1.9e-07 30.9 0.2 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EEB08505.1 - 1.2e-08 34.6 3.3 1.3 8.3 0.0 6.1 5 2 2 7 7 7 3 CLASP N terminal Ipi1_N PF12333.3 EEB08505.1 - 4.8e-05 23.2 0.3 0.57 10.1 0.0 5.1 3 1 2 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Anticodon_1 PF08264.8 EEB08505.1 - 0.0063 16.2 0.1 0.073 12.8 0.0 2.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF2435 PF10363.4 EEB08505.1 - 0.0084 15.9 2.5 1.9 8.4 0.1 4.2 4 1 0 4 4 4 1 Protein of unknown function (DUF2435) Npa1 PF11707.3 EEB08505.1 - 0.0092 15.0 1.5 0.028 13.4 0.3 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 EEB08505.1 - 0.01 15.6 0.1 29 4.6 0.0 5.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FlaF PF07309.6 EEB08505.1 - 0.1 12.4 0.9 3.6 7.4 0.0 3.2 2 1 0 2 2 2 0 Flagellar protein FlaF HEAT_PBS PF03130.11 EEB08505.1 - 2.1 9.0 4.7 1e+02 3.7 0.1 5.3 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Trs65 PF12735.2 EEB08506.1 - 5.6e-36 124.4 2.8 5.6e-36 124.4 1.9 1.7 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF3869 PF12985.2 EEB08506.1 - 0.0047 17.3 0.1 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3869) A2M PF00207.17 EEB08506.1 - 0.019 14.5 0.1 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin family SYF2 PF08231.7 EEB08506.1 - 0.1 12.6 9.3 0.063 13.3 3.0 2.3 1 1 1 2 2 2 0 SYF2 splicing factor JmjC PF02373.17 EEB08507.1 - 2.3e-09 37.4 0.4 3e-08 33.9 0.3 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase AP_endonuc_2 PF01261.19 EEB08508.2 - 6.4e-27 94.2 0.2 1e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_L6e PF01159.14 EEB08509.1 - 4.4e-37 126.6 0.0 6.9e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DJ-1_PfpI PF01965.19 EEB08509.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family KOW PF00467.24 EEB08509.1 - 0.079 12.7 3.0 0.099 12.3 0.4 2.3 2 1 1 3 3 3 0 KOW motif MFS_1 PF07690.11 EEB08510.1 - 1.4e-15 56.8 42.5 9.2e-11 41.0 15.5 3.2 2 1 1 4 4 4 2 Major Facilitator Superfamily TFIID-18kDa PF02269.11 EEB08511.1 - 2.3e-38 129.8 2.6 6e-38 128.5 0.6 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Phage_int_SAM_5 PF13102.1 EEB08511.1 - 0.005 16.8 1.5 0.29 11.1 0.0 2.6 2 1 1 3 3 3 2 Phage integrase SAM-like domain Carb_kinase PF01256.12 EEB08512.1 - 3.8e-56 190.0 0.0 4.5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EEB08512.1 - 0.0022 17.1 0.0 0.0065 15.6 0.0 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Yip1 PF04893.12 EEB08513.2 - 4.8e-09 35.9 13.9 7.7e-09 35.2 9.7 1.4 1 0 0 1 1 1 1 Yip1 domain Cys_Met_Meta_PP PF01053.15 EEB08514.1 - 2.9e-125 417.5 0.0 3.3e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEB08514.1 - 0.00011 21.3 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EEB08514.1 - 0.0013 17.1 0.0 0.0079 14.5 0.0 1.9 2 0 0 2 2 2 1 Methionine gamma-lyase Peptidase_C13 PF01650.13 EEB08515.1 - 2.8e-39 134.9 0.0 3.5e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Host_attach PF10116.4 EEB08515.1 - 0.098 12.8 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells Dynamitin PF04912.9 EEB08516.1 - 7e-09 34.9 26.7 1.4e-08 34.0 18.4 1.6 1 1 0 1 1 1 1 Dynamitin IMPDH PF00478.20 EEB08516.1 - 0.2 10.5 0.4 0.34 9.7 0.1 1.4 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain IncA PF04156.9 EEB08516.1 - 0.36 10.4 38.6 0.67 9.5 2.1 3.7 1 1 3 4 4 4 0 IncA protein MbeD_MobD PF04899.7 EEB08516.1 - 1.1 9.2 11.3 3.1 7.7 0.7 3.6 4 0 0 4 4 4 0 MbeD/MobD like Prefoldin PF02996.12 EEB08516.1 - 1.4 8.5 21.3 0.74 9.4 0.5 4.7 4 2 0 4 4 4 0 Prefoldin subunit Rootletin PF15035.1 EEB08516.1 - 5.7 6.8 24.6 0.031 14.2 8.2 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.7 EEB08516.1 - 6.1 6.6 19.2 0.18 11.5 0.7 3.4 2 1 1 3 3 3 0 Laminin Domain II Z1 PF10593.4 EEB08516.1 - 6.3 5.9 13.0 2.1 7.5 1.1 3.1 2 1 1 3 3 3 0 Z1 domain LXG PF04740.7 EEB08516.1 - 7.1 6.3 21.1 0.45 10.2 3.8 3.7 2 1 1 3 3 3 0 LXG domain of WXG superfamily ATP13 PF12921.2 EEB08517.1 - 1.8e-15 56.4 2.1 2.8e-14 52.5 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial ATPase expression PPR_2 PF13041.1 EEB08517.1 - 4.5e-05 23.3 0.3 7.6 6.5 0.1 4.0 3 1 1 4 4 4 3 PPR repeat family Herpes_U44 PF04533.8 EEB08517.1 - 0.0078 15.4 0.7 10 5.2 0.1 3.2 3 0 0 3 3 3 2 Herpes virus U44 protein LexA_DNA_bind PF01726.11 EEB08517.1 - 0.039 13.5 0.1 0.94 9.0 0.0 2.9 2 0 0 2 2 2 0 LexA DNA binding domain PPR_1 PF12854.2 EEB08517.1 - 0.091 12.2 0.6 8.6 5.9 0.0 2.9 3 0 0 3 3 3 0 PPR repeat Occludin_ELL PF07303.8 EEB08517.1 - 0.57 10.9 7.9 0.51 11.1 1.3 2.7 2 0 0 2 2 2 0 Occludin homology domain XPG_I PF00867.13 EEB08518.2 - 4.5e-20 71.4 0.2 1.5e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 XPG I-region GDA1_CD39 PF01150.12 EEB08519.1 - 4e-114 381.4 0.0 5.5e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PAXNEB PF05625.6 EEB08520.1 - 4.2e-90 302.2 0.0 5e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein IF-2B PF01008.12 EEB08521.1 - 1.5e-66 224.3 0.0 1.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pantoate_ligase PF02569.10 EEB08522.1 - 2.2e-99 331.7 0.1 2.5e-99 331.5 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase B56 PF01603.15 EEB08524.2 - 1.1e-156 521.5 6.8 1.3e-156 521.3 4.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2122 PF09895.4 EEB08524.2 - 0.074 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Cnd3 PF12719.2 EEB08525.1 - 5.6e-84 281.6 3.8 5.6e-84 281.6 2.6 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EEB08525.1 - 2.8e-13 49.9 4.9 6.7e-07 29.4 0.6 5.2 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EEB08525.1 - 1.4e-05 24.7 6.2 18 5.7 0.1 6.9 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EEB08525.1 - 0.028 14.9 11.1 0.069 13.6 0.4 5.2 5 1 2 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.11 EEB08525.1 - 0.083 13.4 0.3 0.51 10.9 0.0 2.7 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Spindle_Spc25 PF08234.7 EEB08526.2 - 7.1e-23 80.4 2.5 2e-22 78.9 1.7 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 HlyD PF00529.15 EEB08526.2 - 0.22 10.7 4.8 0.28 10.4 3.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Fucose_iso_N2 PF07882.7 EEB08526.2 - 0.33 10.5 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain DUF342 PF03961.8 EEB08526.2 - 0.73 8.1 11.6 1 7.6 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1192 PF06698.6 EEB08526.2 - 1.2 9.0 7.4 0.44 10.3 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_Maf PF03131.12 EEB08526.2 - 3 8.1 16.3 0.094 13.0 5.1 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF2346 PF09803.4 EEB08526.2 - 5.3 6.9 13.0 6.8 6.6 2.4 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) SRP54 PF00448.17 EEB08527.1 - 8.2e-81 270.1 0.5 5.2e-79 264.2 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EEB08527.1 - 1.5e-23 83.0 5.3 1.5e-23 83.0 3.7 4.6 3 1 3 6 6 5 1 Signal peptide binding domain SRP54_N PF02881.14 EEB08527.1 - 8.5e-15 54.6 0.4 2.1e-14 53.3 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EEB08527.1 - 1.8e-06 27.9 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EEB08527.1 - 2.2e-06 27.2 0.8 2.7e-05 23.6 0.4 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EEB08527.1 - 2.3e-05 24.1 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EEB08527.1 - 7e-05 22.3 0.1 0.00026 20.4 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EEB08527.1 - 0.00027 20.1 0.0 0.00063 18.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin ArgK PF03308.11 EEB08527.1 - 0.00028 19.7 0.0 0.0025 16.6 0.0 2.2 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EEB08527.1 - 0.00046 20.2 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEB08527.1 - 0.00093 20.0 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EEB08527.1 - 0.0028 17.6 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB08527.1 - 0.003 17.8 0.1 0.015 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB08527.1 - 0.0031 17.6 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEB08527.1 - 0.0042 16.5 0.7 0.0083 15.5 0.5 1.5 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EEB08527.1 - 0.0046 16.1 0.8 1 8.5 0.1 3.1 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 EEB08527.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 EEB08527.1 - 0.015 15.4 0.1 0.079 13.1 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEB08527.1 - 0.018 14.7 0.0 0.066 12.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EEB08527.1 - 0.037 13.6 0.0 0.089 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EEB08527.1 - 0.039 13.0 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 EEB08527.1 - 0.041 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.10 EEB08527.1 - 0.086 12.6 0.6 0.52 10.1 0.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 EEB08527.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.1 EEB08527.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain HDA2-3 PF11496.3 EEB08528.1 - 8.5e-18 64.1 3.1 8.5e-18 64.1 2.2 3.8 2 2 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 BicD PF09730.4 EEB08528.1 - 0.034 12.5 42.0 0.14 10.4 29.1 2.0 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D SapB_1 PF05184.10 EEB08528.1 - 0.28 11.0 2.1 0.64 9.9 0.3 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 UCH PF00443.24 EEB08529.2 - 6.8e-58 195.8 0.1 9.2e-58 195.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB08529.2 - 9.3e-30 104.0 0.0 1.5e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SKIP_SNW PF02731.10 EEB08530.2 - 4.1e-67 224.5 3.0 4.1e-67 224.5 2.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Septin PF00735.13 EEB08531.1 - 1e-97 326.5 0.1 1.7e-97 325.8 0.1 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EEB08531.1 - 3.2e-08 33.2 1.2 1.9e-07 30.7 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEB08531.1 - 4e-06 26.1 0.0 1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEB08531.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEB08531.1 - 0.00019 20.6 0.6 0.027 13.6 0.0 2.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEB08531.1 - 0.0013 18.2 1.6 0.07 12.6 0.2 3.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EEB08531.1 - 0.0022 18.1 0.4 0.0078 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB08531.1 - 0.02 15.1 0.2 0.02 15.1 0.1 2.5 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEB08531.1 - 0.029 13.9 1.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EEB08531.1 - 0.033 13.2 1.1 0.068 12.2 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 EEB08531.1 - 0.075 12.8 6.5 2.4 7.9 0.0 3.2 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 EEB08531.1 - 0.12 12.9 0.7 0.6 10.6 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein DUF2884 PF11101.3 EEB08531.1 - 0.22 10.8 5.1 0.19 11.0 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) DUF3959 PF13105.1 EEB08531.1 - 0.34 10.1 5.4 0.73 9.1 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Mnd1 PF03962.10 EEB08531.1 - 1.9 8.1 14.1 0.28 10.8 6.8 1.8 2 0 0 2 2 2 0 Mnd1 family Ribonuclease_3 PF00636.21 EEB08532.1 - 9.9e-39 132.3 0.0 8.8e-22 77.7 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEB08532.1 - 6.2e-23 81.1 0.0 7.6e-14 51.7 0.0 3.8 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 EEB08532.1 - 1.2e-15 57.1 0.0 4e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EEB08532.1 - 4.1e-15 55.3 0.1 1.2e-14 53.8 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 EEB08532.1 - 7.9e-14 51.5 0.1 5.9e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEB08532.1 - 2.6e-13 50.2 0.7 1.1e-11 44.9 0.1 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EEB08532.1 - 4.9e-06 27.0 0.9 0.0026 18.3 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif SNF2_N PF00176.18 EEB08532.1 - 2.5e-05 23.2 0.0 8.4e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Svf1 PF08622.5 EEB08533.2 - 7.9e-112 373.4 0.7 9.1e-112 373.2 0.5 1.0 1 0 0 1 1 1 1 Svf1-like Antimicrobial14 PF08109.6 EEB08533.2 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Lactocin 705 family Atx10homo_assoc PF09759.4 EEB08534.2 - 2.2e-31 107.5 0.1 1.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 EEB08534.2 - 0.02 14.9 0.1 0.14 12.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat IBN_N PF03810.14 EEB08535.1 - 2.3e-19 69.0 1.1 9.2e-19 67.1 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EEB08535.1 - 3.1e-10 39.1 1.2 1.5e-09 36.8 0.1 2.4 3 0 0 3 3 3 1 Cse1 Xpo1 PF08389.7 EEB08535.1 - 4.6e-08 33.0 7.6 1.2e-07 31.7 0.2 3.7 3 1 1 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 EEB08535.1 - 0.0014 18.8 2.6 1 9.6 0.1 3.2 2 1 0 2 2 2 2 HEAT repeats RIX1 PF08167.7 EEB08535.1 - 0.014 15.0 4.9 0.6 9.7 0.1 3.9 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 EEB08535.1 - 0.42 10.8 2.9 0.92 9.7 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat Actin PF00022.14 EEB08536.2 - 3.4e-79 266.0 0.0 4e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEB08536.2 - 0.063 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Peptidase_C13 PF01650.13 EEB08536.2 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C13 family Dfp1_Him1_M PF08630.5 EEB08537.1 - 7.7e-38 129.0 0.5 1.4e-36 125.0 0.0 2.8 4 0 0 4 4 4 1 Dfp1/Him1, central region zf-DBF PF07535.7 EEB08537.1 - 3.6e-21 74.5 1.0 6.4e-21 73.7 0.7 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EEB08537.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB08537.1 - 0.0028 17.4 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.2 EEB08537.1 - 0.015 15.3 0.2 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) KH_1 PF00013.24 EEB08538.1 - 4.9e-93 304.7 65.9 8.7e-15 54.1 0.9 14.3 14 0 0 14 14 14 12 KH domain KH_3 PF13014.1 EEB08538.1 - 3.6e-62 205.1 48.5 1.3e-10 40.7 1.5 13.5 14 0 0 14 14 14 11 KH domain KH_2 PF07650.12 EEB08538.1 - 1e-06 28.1 45.3 0.024 14.1 2.0 10.3 8 3 3 11 11 11 6 KH domain SLS PF14611.1 EEB08538.1 - 0.0022 17.4 25.8 5.2 6.4 1.0 7.7 5 2 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator zf-C2H2_2 PF12756.2 EEB08539.1 - 1.6e-33 114.8 16.0 8.2e-30 102.9 1.5 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEB08539.1 - 7.2e-11 41.9 20.4 6.1e-05 23.0 0.4 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB08539.1 - 8.5e-06 25.8 0.4 8.5e-06 25.8 0.3 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 EEB08539.1 - 0.0013 19.3 12.0 0.15 12.6 2.8 3.0 2 1 1 3 3 3 2 Protein of unknown function (FYDLN_acid) SnoaL_2 PF12680.2 EEB08539.1 - 0.0015 18.9 0.0 0.079 13.3 0.0 3.0 2 1 0 2 2 2 1 SnoaL-like domain zf-C2H2 PF00096.21 EEB08539.1 - 0.0042 17.3 20.9 0.59 10.5 0.2 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-Mss51 PF13824.1 EEB08539.1 - 0.044 13.6 3.6 3.8 7.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF629 PF04780.7 EEB08539.1 - 0.045 12.2 10.7 0.086 11.3 0.0 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 EEB08539.1 - 0.1 12.9 19.1 0.47 10.9 0.9 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.1 EEB08539.1 - 0.17 11.4 1.0 1.1 8.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.7 EEB08539.1 - 0.58 9.6 2.9 3.9 6.9 0.0 3.0 3 0 0 3 3 3 0 HypF finger AKAP95 PF04988.7 EEB08539.1 - 1.5 8.5 9.5 5 6.8 0.7 3.1 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) STAG PF08514.6 EEB08540.1 - 3.2e-11 42.9 0.5 2.3e-10 40.1 0.0 2.7 2 0 0 2 2 2 1 STAG domain Cyclin_N PF00134.18 EEB08541.1 - 2.6e-41 140.1 0.1 6.1e-41 138.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB08541.1 - 1.3e-30 105.7 0.1 2.5e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PGP_phosphatase PF09419.5 EEB08542.2 - 4.7e-45 152.9 0.0 5.5e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EEB08542.2 - 1.6e-08 34.1 0.0 3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEB08542.2 - 0.00091 19.4 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3600 PF12207.3 EEB08542.2 - 0.012 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Fe-S_biosyn PF01521.15 EEB08543.1 - 1.2e-20 73.4 0.1 1.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MAGE PF01454.14 EEB08544.1 - 1.3e-28 99.6 0.0 2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 MAGE family Myosin_head PF00063.16 EEB08545.1 - 7.6e-247 820.7 6.2 7.6e-247 820.7 4.3 2.7 3 0 0 3 3 2 1 Myosin head (motor domain) Myosin_N PF02736.14 EEB08545.1 - 3.9e-06 26.4 0.1 9.9e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_13 PF13166.1 EEB08545.1 - 2.5e-05 22.9 115.3 0.0033 15.9 28.1 4.5 1 1 3 4 4 4 3 AAA domain MAD PF05557.8 EEB08545.1 - 8.6e-05 20.8 56.6 8.6e-05 20.8 39.2 4.2 1 1 2 3 3 3 1 Mitotic checkpoint protein CENP-F_leu_zip PF10473.4 EEB08545.1 - 0.0057 16.5 14.2 0.0057 16.5 9.8 8.2 1 1 7 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Agenet PF05641.7 EEB08545.1 - 0.023 14.8 0.0 0.28 11.3 0.0 2.8 2 0 0 2 2 2 0 Agenet domain Reo_sigmaC PF04582.7 EEB08545.1 - 0.033 13.3 57.0 0.22 10.6 5.3 6.3 1 1 6 7 7 7 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EEB08545.1 - 0.045 13.5 135.6 0.087 12.6 5.7 7.1 1 1 5 6 6 5 0 Autophagy protein 16 (ATG16) AAA_19 PF13245.1 EEB08545.1 - 0.047 13.4 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EEB08545.1 - 0.18 11.9 0.0 0.18 11.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain Myosin_tail_1 PF01576.14 EEB08545.1 - 0.92 7.1 146.0 0.76 7.4 51.5 4.9 1 1 2 4 4 4 0 Myosin tail TPR_MLP1_2 PF07926.7 EEB08545.1 - 3.1 7.5 146.6 0.13 12.0 7.1 9.5 1 1 8 9 9 9 0 TPR/MLP1/MLP2-like protein CNH PF00780.17 EEB08546.2 - 3.4e-34 118.5 0.0 5.5e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EEB08546.2 - 7.9e-33 113.8 0.0 1.7e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EEB08546.2 - 3.9e-19 68.9 3.1 1.7e-18 66.8 2.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEB08546.2 - 2.2e-08 34.2 1.4 1e-07 32.1 1.0 2.3 1 1 0 1 1 1 1 PH domain CNH PF00780.17 EEB08547.1 - 1.1e-83 280.9 0.0 1.9e-83 280.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EEB08547.1 - 2.9e-36 124.4 0.2 6.4e-36 123.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEB08547.1 - 2.5e-34 118.7 0.6 4.3e-34 117.9 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EEB08547.1 - 1.1e-11 44.2 0.0 2.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNase PF00565.12 EEB08548.1 - 5.6e-65 216.3 0.0 4e-14 52.7 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EEB08548.1 - 7.3e-20 71.0 0.0 2.1e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Tudor domain PRK PF00485.13 EEB08550.2 - 1.7e-59 200.6 0.0 2.5e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EEB08550.2 - 3.8e-27 94.8 0.0 6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EEB08550.2 - 3.1e-10 40.9 0.0 7.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB08550.2 - 1.3e-08 35.2 0.0 2.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEB08550.2 - 1.3e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EEB08550.2 - 2.5e-05 24.1 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEB08550.2 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB08550.2 - 0.0027 17.8 0.0 0.0078 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EEB08550.2 - 0.0028 17.3 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA PF00004.24 EEB08550.2 - 0.006 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EEB08550.2 - 0.011 15.5 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EEB08550.2 - 0.014 14.8 0.0 0.029 13.8 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EEB08550.2 - 0.016 14.8 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EEB08550.2 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EEB08550.2 - 0.028 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 EEB08550.2 - 0.04 12.7 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.12 EEB08550.2 - 0.04 13.2 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.9 EEB08550.2 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEB08550.2 - 0.054 13.3 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEB08550.2 - 0.064 12.9 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SE PF00437.15 EEB08550.2 - 0.069 12.0 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EEB08550.2 - 0.087 13.3 0.3 4.9 7.6 0.1 3.1 2 2 1 3 3 3 0 Miro-like protein AAA_24 PF13479.1 EEB08550.2 - 0.089 12.3 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain dNK PF01712.14 EEB08550.2 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_21 PF13304.1 EEB08550.2 - 0.13 12.2 2.5 1.1 9.1 1.7 2.2 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EEB08551.1 - 2.4e-61 207.1 0.1 2.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08551.1 - 5.9e-37 127.1 0.0 7.3e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08551.1 - 6.3e-09 35.2 0.2 4.9e-06 25.7 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEB08551.1 - 1.4e-05 24.2 0.2 2.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB08551.1 - 0.0018 18.0 0.2 0.0071 16.0 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EEB08551.1 - 0.06 12.1 0.1 0.1 11.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2404 PF10296.4 EEB08552.1 - 7.8e-09 35.5 0.1 1.8e-05 24.7 0.0 2.9 2 1 1 3 3 3 2 Putative integral membrane protein conserved region (DUF2404) BCAS2 PF05700.6 EEB08553.2 - 3.2e-20 72.5 0.1 3.8e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MTHFR PF02219.12 EEB08554.1 - 2.8e-118 394.1 0.0 3.9e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_8 PF05148.10 EEB08555.1 - 4e-84 281.6 0.0 4.8e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EEB08555.1 - 5.8e-10 39.5 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB08555.1 - 4.2e-06 26.4 0.1 0.0029 17.2 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.9 EEB08555.1 - 0.001 18.4 0.1 1.3 8.3 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.13 EEB08555.1 - 0.0059 15.7 0.0 0.021 13.9 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EEB08555.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08555.1 - 0.017 15.4 0.3 0.37 11.1 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08555.1 - 0.024 15.1 0.1 0.79 10.3 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08555.1 - 0.35 11.3 2.3 0.87 10.1 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain His_Phos_1 PF00300.17 EEB08556.1 - 5.8e-18 65.4 0.0 7.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HMG-CoA_red PF00368.13 EEB08557.2 - 2.9e-155 516.5 2.6 3.9e-155 516.1 1.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EEB08557.2 - 5.5e-05 22.9 0.1 0.00095 18.8 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain with HPIH motif DUF3173 PF11372.3 EEB08557.2 - 0.042 13.4 0.1 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Reg_prop PF07494.6 EEB08558.1 - 0.1 12.6 0.0 2.7 8.3 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller TPR_11 PF13414.1 EEB08559.1 - 7.8e-59 195.2 24.1 5.5e-19 67.5 0.2 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EEB08559.1 - 1.3e-48 160.6 25.1 2.4e-07 30.0 0.0 9.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EEB08559.1 - 6.7e-37 122.4 25.0 0.00014 21.4 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EEB08559.1 - 2e-22 78.9 19.1 1.1e-10 41.2 1.5 6.5 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08559.1 - 3.1e-21 75.4 6.6 7.7e-05 23.2 0.0 6.3 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08559.1 - 7.3e-18 63.4 10.0 0.046 14.3 0.1 8.6 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08559.1 - 4.9e-16 58.8 11.3 0.0043 17.3 0.2 7.3 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEB08559.1 - 5.7e-16 57.0 18.0 0.0045 16.6 0.2 8.6 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEB08559.1 - 1.5e-14 52.5 4.8 5.1e-06 25.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEB08559.1 - 2.7e-13 48.9 16.0 0.0032 17.5 0.1 9.4 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEB08559.1 - 1.5e-10 40.7 2.1 0.0038 17.0 0.0 5.4 3 2 3 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEB08559.1 - 9.4e-07 28.6 2.4 7.1 6.6 0.0 6.4 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EEB08559.1 - 2.9e-06 27.3 15.6 0.092 12.8 0.2 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEB08559.1 - 3.6e-05 23.9 23.3 0.017 15.5 0.1 7.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEB08559.1 - 0.00037 20.3 6.1 0.96 9.4 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 EEB08559.1 - 0.00081 19.1 13.9 0.71 9.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.7 EEB08559.1 - 0.0016 18.0 6.6 0.32 10.5 0.1 4.3 4 0 0 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.4 EEB08559.1 - 0.06 12.6 1.2 0.49 9.6 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR TPR_20 PF14561.1 EEB08559.1 - 2.2 8.4 0.0 2.2 8.4 0.0 4.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEB08559.1 - 2.8 8.6 7.0 55 4.6 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EEB08560.2 - 4.5e-84 281.9 0.0 5.9e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Alb1 PF09135.6 EEB08561.1 - 2.3e-08 34.6 21.5 2.8e-08 34.3 14.9 1.0 1 0 0 1 1 1 1 Alb1 Ribonuclease_T2 PF00445.13 EEB08561.1 - 0.45 10.0 3.8 0.65 9.5 2.6 1.2 1 0 0 1 1 1 0 Ribonuclease T2 family DUF2228 PF10228.4 EEB08561.1 - 1.4 8.4 7.2 1.4 8.4 5.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) SAE2 PF08573.5 EEB08561.1 - 3.8 8.2 8.6 5.4 7.7 6.0 1.5 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus PI3_PI4_kinase PF00454.22 EEB08562.1 - 5.3e-42 143.9 0.0 1.5e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EEB08562.1 - 2.5e-19 69.5 2.2 2.5e-19 69.5 1.5 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EEB08562.1 - 1.2e-09 37.4 0.0 3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_12 PF13424.1 EEB08562.1 - 0.00017 21.4 2.3 0.57 10.1 0.4 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat CRAL_TRIO PF00650.15 EEB08563.1 - 1.1e-36 125.7 0.0 2.1e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEB08563.1 - 1.9e-10 40.6 0.6 4.4e-10 39.5 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEB08563.1 - 0.00061 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Rep_fac-A_3 PF08661.6 EEB08564.1 - 2.4e-26 91.7 0.1 2.6e-26 91.6 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Glyco_hydro_66 PF13199.1 EEB08564.1 - 0.043 12.2 0.0 0.053 11.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Flavokinase PF01687.12 EEB08564.1 - 0.1 12.4 0.1 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Riboflavin kinase DUF4431 PF14485.1 EEB08564.1 - 0.2 11.2 0.6 0.48 10.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) PGM_PMM_I PF02878.11 EEB08565.1 - 1.1e-19 70.3 0.1 3e-08 33.2 0.0 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEB08565.1 - 4.6e-13 49.3 0.0 2.3e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEB08565.1 - 4.9e-09 36.0 0.0 1.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EEB08565.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III HhH-GPD PF00730.20 EEB08566.1 - 3.3e-19 69.1 0.0 5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEB08566.1 - 3.2e-07 29.6 0.0 9.4e-07 28.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Solute_trans_a PF03619.11 EEB08567.1 - 1.8e-86 289.8 5.5 2.2e-86 289.6 3.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.2 EEB08567.1 - 6.8 6.9 6.4 1.6 8.9 1.2 2.4 2 1 1 3 3 3 0 PrgI family protein Clat_adaptor_s PF01217.15 EEB08568.1 - 9.8e-50 167.9 0.2 1.2e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MMS1_N PF10433.4 EEB08570.2 - 9.8e-94 314.2 1.8 1.9e-93 313.3 1.2 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EEB08570.2 - 1.1e-16 60.9 1.7 9e-16 57.8 0.1 2.7 3 0 0 3 3 3 1 CPSF A subunit region Nup_retrotrp_bd PF10599.4 EEB08571.1 - 0.008 16.8 22.0 0.008 16.8 15.3 9.7 2 2 5 7 7 7 1 Retro-transposon transporting motif DEAD PF00270.24 EEB08572.1 - 7.4e-46 155.7 0.0 1.8e-45 154.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08572.1 - 1e-24 86.1 0.1 3.6e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB08572.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEB08572.1 - 0.14 11.9 1.6 0.29 10.9 0.1 2.3 3 0 0 3 3 3 0 Part of AAA domain AMP-binding PF00501.23 EEB08573.1 - 2.2e-50 171.2 0.0 1.6e-29 102.5 0.0 4.9 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EEB08573.1 - 8.5e-09 35.9 1.4 1.9e-08 34.8 1.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EEB08573.1 - 0.097 12.4 1.6 0.33 10.8 1.1 1.8 1 0 0 1 1 1 0 Gas vesicle protein G GTP_EFTU PF00009.22 EEB08574.1 - 3.1e-33 114.7 0.0 3.1e-33 114.7 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEB08574.1 - 1.2e-19 70.1 0.1 3.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEB08574.1 - 3.3e-12 46.3 4.0 5.5e-08 32.8 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB08574.1 - 4.2e-07 29.9 0.7 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EEB08574.1 - 3.1e-05 23.5 0.2 9.9e-05 21.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EEB08574.1 - 0.0001 21.9 0.0 0.00096 18.7 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EEB08574.1 - 0.0044 17.1 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 EEB08574.1 - 0.024 14.0 0.0 0.095 12.0 0.0 2.0 1 1 0 1 1 1 0 Ras family PCI PF01399.22 EEB08575.1 - 3.9e-09 36.7 2.3 5.6e-09 36.2 0.1 2.5 2 2 1 3 3 3 1 PCI domain TPR_12 PF13424.1 EEB08575.1 - 2.4e-08 33.7 2.3 0.00019 21.3 0.9 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB08575.1 - 2.4e-06 26.8 1.9 0.057 13.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08575.1 - 7.7e-06 26.1 1.3 1.9e-05 24.9 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 EEB08575.1 - 7.9e-05 22.6 0.2 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEB08575.1 - 0.00012 21.6 0.6 4 7.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB08575.1 - 0.00053 19.5 0.7 0.0076 15.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEB08575.1 - 0.00055 19.7 0.5 6.7 6.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEB08575.1 - 0.0029 17.7 3.4 0.034 14.2 0.1 3.0 1 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEB08575.1 - 0.0044 17.5 0.1 2.7 8.8 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB08575.1 - 0.0054 16.2 1.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EEB08575.1 - 0.015 14.7 0.3 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_16 PF13432.1 EEB08575.1 - 0.022 15.4 0.3 0.11 13.1 0.0 2.3 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB08575.1 - 0.033 14.6 0.7 13 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Prenyltransf PF01255.14 EEB08575.1 - 0.06 12.4 0.8 0.1 11.7 0.5 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase TPR_11 PF13414.1 EEB08575.1 - 0.066 12.8 2.3 0.27 10.9 0.4 2.4 1 1 1 2 2 2 0 TPR repeat Apc5 PF12862.2 EEB08575.1 - 0.66 9.8 4.9 0.62 9.9 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DRMBL PF07522.9 EEB08577.1 - 1.5e-26 92.5 0.0 3.9e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEB08577.1 - 5.4e-10 39.1 0.1 9.8e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEB08577.1 - 7.1e-05 22.5 3.8 0.00037 20.2 2.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HLH PF00010.21 EEB08578.1 - 4.4e-14 51.9 0.7 7.9e-14 51.0 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 EEB08578.1 - 0.31 9.2 19.0 0.38 8.9 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPC22 PF04573.7 EEB08579.1 - 2.4e-27 95.2 0.5 3.9e-18 65.2 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase subunit DUF2434 PF10361.4 EEB08580.1 - 3.7e-43 147.6 6.6 4.8e-43 147.3 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) SURF4 PF02077.10 EEB08580.1 - 0.097 12.0 3.0 0.28 10.4 0.6 2.2 2 0 0 2 2 2 0 SURF4 family Inositol_P PF00459.20 EEB08581.1 - 1.7e-69 234.1 0.1 2.2e-69 233.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family SUZ-C PF12901.2 EEB08581.1 - 0.15 11.7 0.2 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 SUZ-C motif CRAL_TRIO PF00650.15 EEB08582.1 - 8.1e-44 148.9 0.1 1.5e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEB08582.1 - 3.6e-14 52.6 0.3 1.1e-13 51.1 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEB08582.1 - 2.6e-09 37.1 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.1 EEB08582.1 - 0.011 15.2 0.1 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Apt1 PF10351.4 EEB08582.1 - 0.11 11.2 3.8 0.21 10.4 2.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPP_enzyme_N PF02776.13 EEB08583.1 - 5.3e-34 117.1 0.0 9.7e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEB08583.1 - 6.5e-27 93.9 0.0 1.5e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEB08583.1 - 8.8e-18 64.3 0.2 3.1e-17 62.5 0.0 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEB08583.1 - 0.00033 19.6 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase VWA_2 PF13519.1 EEB08583.1 - 0.00044 20.4 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Peptidase_M17 PF00883.16 EEB08584.1 - 3.5e-121 403.8 0.2 3.5e-121 403.8 0.1 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EEB08584.1 - 1.1e-12 47.8 0.2 2.3e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol_A_exo1 PF01612.15 EEB08585.1 - 1.5e-49 167.8 0.2 3.5e-48 163.3 0.1 2.4 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EEB08585.1 - 7.9e-20 70.9 2.6 1.6e-18 66.7 0.1 3.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EEB08585.1 - 7e-16 57.7 0.0 1.8e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain CRAL_TRIO PF00650.15 EEB08586.1 - 8.6e-38 129.3 0.0 1.4e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEB08586.1 - 2.7e-08 33.8 0.7 2.7e-08 33.8 0.5 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEB08586.1 - 2.2e-05 24.3 0.0 0.00014 21.7 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RRM_1 PF00076.17 EEB08587.2 - 1.1e-08 34.5 0.0 2.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08587.2 - 7.7e-07 29.0 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08587.2 - 0.0024 17.6 0.6 0.0042 16.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEP PF00610.16 EEB08588.2 - 3.5e-14 52.2 0.0 8.1e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 EEB08588.2 - 8.1e-12 45.0 0.2 3.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain p450 PF00067.17 EEB08590.2 - 9e-74 248.6 0.0 1.1e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mnd1 PF03962.10 EEB08591.1 - 2.2e-55 187.2 7.5 2.5e-55 187.0 5.2 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 EEB08591.1 - 0.00064 19.3 7.5 0.0019 17.7 5.3 1.7 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 EEB08591.1 - 0.0012 18.9 0.5 0.0055 16.7 0.0 2.2 1 1 0 2 2 2 1 Penicillinase repressor DUF2802 PF10975.3 EEB08591.1 - 0.008 15.9 5.2 6.8 6.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Cep57_MT_bd PF06657.8 EEB08591.1 - 0.0085 16.0 2.7 1.3 9.0 0.0 3.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 TFIIE_alpha PF02002.12 EEB08591.1 - 0.011 15.2 2.5 0.018 14.5 0.1 2.2 2 1 1 3 3 3 0 TFIIE alpha subunit Tropomyosin_1 PF12718.2 EEB08591.1 - 0.015 15.1 10.2 0.029 14.2 7.1 1.5 1 0 0 1 1 1 0 Tropomyosin like TrmB PF01978.14 EEB08591.1 - 0.03 14.0 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Leu_zip PF15294.1 EEB08591.1 - 0.032 13.3 8.1 0.045 12.8 5.6 1.2 1 0 0 1 1 1 0 Leucine zipper Syntaxin_2 PF14523.1 EEB08591.1 - 0.049 13.6 2.9 1.7 8.6 3.1 2.4 1 1 1 2 2 2 0 Syntaxin-like protein FUR PF01475.14 EEB08591.1 - 0.05 13.5 1.6 0.063 13.1 0.1 1.9 2 0 0 2 2 2 0 Ferric uptake regulator family GntR PF00392.16 EEB08591.1 - 0.052 12.9 0.2 0.75 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Atg14 PF10186.4 EEB08591.1 - 0.12 11.2 6.7 0.16 10.8 4.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3734 PF12536.3 EEB08591.1 - 0.15 12.2 3.5 14 5.8 0.6 3.1 2 1 1 3 3 3 0 Patatin phospholipase V_ATPase_I PF01496.14 EEB08591.1 - 0.23 9.2 1.6 0.27 9.0 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.4 EEB08591.1 - 0.93 9.7 4.6 0.78 9.9 0.3 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lzipper-MIP1 PF14389.1 EEB08591.1 - 1.2 9.3 9.6 7.8 6.6 0.4 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 EEB08591.1 - 2.3 8.2 11.9 28 4.7 7.9 2.3 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 EEB08591.1 - 2.6 7.5 10.3 6.2 6.3 0.9 2.6 1 1 1 2 2 2 0 Septum formation initiator Cauli_AT PF03233.8 EEB08591.1 - 4.1 7.0 7.8 16 5.1 2.1 2.8 2 1 1 3 3 3 0 Aphid transmission protein YvrJ PF12841.2 EEB08591.1 - 4.8 6.5 5.8 8.8 5.7 0.4 2.4 2 0 0 2 2 2 0 YvrJ protein family IncA PF04156.9 EEB08591.1 - 5.2 6.6 17.7 0.64 9.5 8.2 1.9 1 1 0 2 2 2 0 IncA protein DUF4404 PF14357.1 EEB08591.1 - 6.5 7.2 7.4 2.9 8.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF342 PF03961.8 EEB08591.1 - 6.9 4.9 8.1 8.8 4.6 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MerR-DNA-bind PF09278.6 EEB08591.1 - 8.6 6.8 7.8 16 5.9 0.3 3.6 3 1 1 4 4 4 0 MerR, DNA binding UCH PF00443.24 EEB08592.1 - 4.9e-58 196.3 2.3 7.5e-58 195.7 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB08592.1 - 8.1e-19 68.1 1.4 1.3e-18 67.5 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEB08592.1 - 2.5e-11 43.5 9.8 2.5e-11 43.5 6.8 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Pkinase PF00069.20 EEB08593.1 - 2.5e-71 239.9 0.0 4.2e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08593.1 - 1.1e-48 165.6 0.0 1.9e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08593.1 - 3.3e-07 29.5 0.0 4.3e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEB08593.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB08593.1 - 0.046 13.4 0.2 0.28 10.8 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Lgl_C PF08596.5 EEB08594.1 - 4.6e-57 193.2 0.0 3.8e-56 190.2 0.0 2.0 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal DUF367 PF04034.8 EEB08595.1 - 8.1e-54 180.6 0.0 1.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EEB08595.1 - 1.7e-12 46.7 0.0 3.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.14 EEB08596.1 - 5e-43 146.1 0.0 1.2e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.15 EEB08596.1 - 2.2e-08 34.4 0.0 5.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EEB08596.1 - 3.5e-06 26.8 2.0 7.3e-06 25.8 0.5 2.2 2 0 0 2 2 2 1 GAT domain Myosin_tail_1 PF01576.14 EEB08597.1 - 5.6e-07 27.7 395.2 0.00014 19.8 39.6 8.2 3 2 3 8 8 8 6 Myosin tail Filament PF00038.16 EEB08597.1 - 3e-06 26.9 331.0 0.0013 18.3 14.4 12.7 1 1 9 11 11 11 6 Intermediate filament protein AAA_13 PF13166.1 EEB08597.1 - 7.3e-06 24.7 316.4 0.0072 14.8 16.1 11.0 1 1 10 12 12 12 9 AAA domain DUF3584 PF12128.3 EEB08597.1 - 0.00021 18.8 56.6 0.00021 18.8 39.2 7.9 1 1 7 8 8 8 4 Protein of unknown function (DUF3584) DUF2968 PF11180.3 EEB08597.1 - 0.00095 18.5 15.6 0.00095 18.5 10.8 19.1 3 2 14 20 20 20 2 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 EEB08597.1 - 0.004 16.3 204.0 0.017 14.3 5.8 16.4 2 2 16 18 18 18 9 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EEB08597.1 - 0.0057 16.4 11.1 0.0057 16.4 7.7 32.0 9 5 24 35 35 35 8 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEB08597.1 - 0.31 10.6 434.5 0.21 11.1 17.5 19.3 1 1 17 19 19 19 0 IncA protein TSC22 PF01166.13 EEB08598.2 - 0.0068 16.3 3.9 0.068 13.1 0.2 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF745 PF05335.8 EEB08598.2 - 0.058 12.9 1.6 0.075 12.5 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.17 EEB08598.2 - 0.076 13.0 3.4 0.13 12.3 1.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ING PF12998.2 EEB08598.2 - 0.63 10.3 8.2 1.1 9.5 5.7 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding bZIP_1 PF00170.16 EEB08598.2 - 0.81 9.6 3.8 0.41 10.6 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 EEB08598.2 - 1.2 8.7 15.0 2.5 7.6 0.6 2.1 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 EEB08598.2 - 1.2 9.5 9.8 5.1 7.4 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 EEB08598.2 - 2.4 8.2 11.2 2.9 8.0 0.5 2.7 1 1 2 3 3 3 0 Central kinetochore-associated His_Phos_1 PF00300.17 EEB08600.2 - 4.2e-26 91.9 0.0 5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CheR PF01739.13 EEB08600.2 - 0.043 13.1 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FSH1 PF03959.8 EEB08601.1 - 3.8e-43 147.4 0.0 6.3e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EEB08601.1 - 0.00057 19.3 0.0 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEB08601.1 - 0.0022 17.7 0.0 0.0051 16.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pur_DNA_glyco PF02245.11 EEB08601.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) TFIIS_C PF01096.13 EEB08602.1 - 5e-22 77.2 14.6 2.5e-20 71.8 2.3 2.9 2 1 0 2 2 2 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEB08602.1 - 1.6e-15 56.5 0.4 1.6e-15 56.5 0.3 2.6 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.7 EEB08602.1 - 0.0022 17.2 6.5 0.019 14.2 0.0 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EEB08602.1 - 0.0024 17.6 6.7 0.0072 16.1 0.1 2.4 2 1 0 2 2 2 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EEB08602.1 - 0.0024 17.6 7.1 0.14 11.9 0.7 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 EEB08602.1 - 0.0072 15.9 1.7 0.0072 15.9 1.2 2.0 3 0 0 3 3 1 1 Zinc finger found in FPG and IleRS Elf1 PF05129.8 EEB08602.1 - 0.016 14.9 3.4 0.08 12.6 0.1 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.6 EEB08602.1 - 0.035 13.6 0.4 0.7 9.4 0.0 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain C1_4 PF07975.7 EEB08602.1 - 0.049 13.6 5.2 1.4 8.9 0.1 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EEB08602.1 - 0.057 13.2 2.7 0.082 12.7 0.4 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Baculo_LEF5_C PF11792.3 EEB08602.1 - 0.18 11.2 0.4 0.18 11.2 0.2 2.2 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain C1_1 PF00130.17 EEB08602.1 - 0.22 11.2 5.9 0.32 10.7 0.2 2.6 3 1 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.7 EEB08602.1 - 0.23 10.9 4.0 6.7 6.1 0.4 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2387 PF09526.5 EEB08602.1 - 0.24 11.3 5.8 2.4 8.1 0.6 2.5 1 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_2 PF13240.1 EEB08602.1 - 0.27 10.7 11.0 8 6.0 4.1 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EEB08602.1 - 0.36 10.8 7.0 4.9 7.1 0.4 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EEB08602.1 - 0.39 11.0 4.9 3.3 8.0 1.4 2.8 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_3 PF07649.7 EEB08602.1 - 0.42 10.6 0.3 0.42 10.6 0.2 2.8 3 0 0 3 3 3 0 C1-like domain OrfB_Zn_ribbon PF07282.6 EEB08602.1 - 0.5 10.0 5.5 2.2 7.9 0.4 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EEB08602.1 - 0.57 9.4 10.5 4.3 6.6 3.5 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EEB08602.1 - 1 9.0 7.2 1.4 8.6 1.5 2.7 2 1 0 2 2 2 0 Nudix N-terminal GFA PF04828.9 EEB08602.1 - 1.1 9.2 6.7 1.4 8.9 0.4 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme IBR PF01485.16 EEB08602.1 - 1.1 9.1 11.7 2.2 8.2 0.6 2.6 2 1 0 2 2 2 0 IBR domain zf-Mss51 PF13824.1 EEB08602.1 - 1.8 8.4 5.9 3.9 7.3 0.3 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin PF00301.15 EEB08602.1 - 3.3 7.6 8.5 6.8 6.6 0.6 3.3 3 0 0 3 3 3 0 Rubredoxin UPF0547 PF10571.4 EEB08602.1 - 9.9 5.9 14.8 1.9 8.2 0.2 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Ribosomal_S8 PF00410.14 EEB08603.1 - 3.3e-27 94.8 0.2 4.4e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Asp_protease PF09668.5 EEB08604.1 - 2.6e-56 188.5 0.0 7.6e-56 187.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease DUF2781 PF10914.3 EEB08604.1 - 3.7e-21 75.4 14.9 1.4e-20 73.5 10.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) Asp_protease_2 PF13650.1 EEB08604.1 - 1.2e-11 44.9 0.1 3.9e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EEB08604.1 - 4.6e-08 33.0 0.0 3.4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEB08604.1 - 2.4e-06 27.2 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EEB08604.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease SPC25 PF06703.6 EEB08604.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_A2B PF12384.3 EEB08604.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ty3 transposon peptidase DIE2_ALG10 PF04922.7 EEB08605.2 - 6.4e-39 134.0 0.5 8e-39 133.7 0.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family dCMP_cyt_deam_1 PF00383.17 EEB08608.2 - 7.4e-24 83.3 2.1 7.4e-24 83.3 1.5 1.5 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region KxDL PF10241.4 EEB08609.1 - 0.065 13.1 2.8 2.7 7.9 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein Sugarporin_N PF11471.3 EEB08609.1 - 0.37 10.4 5.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FtsJ PF01728.14 EEB08610.2 - 1.6e-54 184.6 0.0 1.8e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EEB08610.2 - 0.00086 18.9 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEB08610.2 - 0.003 17.3 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_Mon PF14314.1 EEB08610.2 - 0.066 11.0 0.1 0.077 10.8 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase Rft-1 PF04506.8 EEB08611.1 - 2.7e-102 342.9 20.4 3.4e-102 342.6 14.1 1.0 1 0 0 1 1 1 1 Rft protein His_biosynth PF00977.16 EEB08612.1 - 3.6e-46 157.2 0.0 9e-46 155.9 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EEB08612.1 - 9.6e-27 93.6 0.0 1.5e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EEB08612.1 - 3e-07 30.1 0.0 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EEB08612.1 - 1.1e-05 25.1 0.0 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Dus PF01207.12 EEB08612.1 - 0.0045 15.8 0.0 0.0097 14.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EEB08612.1 - 0.044 13.2 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 Peptidase C26 SAGA-Tad1 PF12767.2 EEB08613.2 - 3.7e-42 144.7 0.6 5.1e-42 144.2 0.4 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Xan_ur_permease PF00860.15 EEB08614.2 - 2.8e-24 85.3 26.8 2.8e-24 85.3 18.6 2.4 2 1 0 2 2 2 1 Permease family FA_hydroxylase PF04116.8 EEB08616.2 - 1.4e-18 67.3 12.3 1.4e-18 67.3 8.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PIF1 PF05970.9 EEB08617.2 - 1.3e-61 208.5 0.9 4.1e-48 164.1 0.0 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EEB08617.2 - 5.8e-17 61.9 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB08617.2 - 3.9e-08 33.4 0.1 1.3e-07 31.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain Herpes_Helicase PF02689.9 EEB08617.2 - 3.9e-06 24.9 0.1 0.00012 20.0 0.0 2.3 3 0 0 3 3 3 1 Helicase AAA_19 PF13245.1 EEB08617.2 - 2.5e-05 23.9 0.1 5.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EEB08617.2 - 3e-05 24.0 0.2 0.0003 20.8 0.1 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EEB08617.2 - 8.3e-05 22.2 0.6 0.14 11.6 0.2 3.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EEB08617.2 - 0.00016 21.2 0.1 0.064 12.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EEB08617.2 - 0.00032 19.9 0.0 0.00078 18.6 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EEB08617.2 - 0.00056 18.8 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EEB08617.2 - 0.0024 17.8 0.1 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 EEB08617.2 - 0.0045 16.0 0.1 0.036 13.0 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EEB08617.2 - 0.0063 16.7 0.0 0.023 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEB08617.2 - 0.011 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EEB08617.2 - 0.017 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EEB08617.2 - 0.02 14.7 0.2 0.19 11.6 0.0 2.7 2 1 1 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEB08617.2 - 0.025 13.1 0.2 0.056 12.0 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 EEB08617.2 - 0.033 13.0 0.1 0.057 12.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EEB08617.2 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EEB08617.2 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Helicase_RecD PF05127.9 EEB08617.2 - 0.052 13.1 0.5 0.32 10.5 0.4 2.3 1 1 0 1 1 1 0 Helicase AAA_5 PF07728.9 EEB08617.2 - 0.063 12.9 1.1 1.1 8.9 0.8 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EEB08617.2 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EEB08617.2 - 0.079 12.6 0.8 0.45 10.2 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.2 EEB08617.2 - 0.14 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Pex19 PF04614.7 EEB08618.2 - 3.3e-29 102.2 11.3 4.3e-29 101.8 7.8 1.1 1 0 0 1 1 1 1 Pex19 protein family DUF1825 PF08855.5 EEB08618.2 - 0.023 14.7 0.2 0.023 14.7 0.1 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF1825) Type_III_YscX PF09474.5 EEB08618.2 - 0.073 13.1 2.8 0.091 12.7 0.5 2.0 2 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF3695 PF12494.3 EEB08619.1 - 0.13 12.0 0.6 0.17 11.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3695) CIA30 PF08547.7 EEB08620.1 - 2.7e-36 124.7 0.1 3.1e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Snf7 PF03357.16 EEB08621.1 - 2.3e-20 72.6 12.9 3.1e-20 72.2 9.0 1.1 1 0 0 1 1 1 1 Snf7 vATP-synt_AC39 PF01992.11 EEB08621.1 - 0.0027 16.9 0.3 0.0036 16.4 0.2 1.2 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CS PF04969.11 EEB08622.1 - 1.1e-08 35.4 0.5 1.9e-08 34.6 0.3 1.3 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.22 EEB08623.1 - 2.5e-49 167.1 0.0 2e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEB08623.1 - 1.8e-35 122.6 43.7 1.1e-20 74.1 15.1 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEB08623.1 - 1e-11 45.3 3.5 0.00066 19.7 0.8 4.6 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEB08623.1 - 2.4e-10 40.0 0.0 0.0008 18.6 0.1 4.0 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEB08623.1 - 1.2e-08 34.6 0.3 0.007 15.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEB08623.1 - 4e-07 29.4 0.8 0.024 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EEB08623.1 - 3.1e-06 27.6 0.2 0.043 14.3 0.0 3.5 3 0 0 3 3 3 2 Miro-like protein AAA_16 PF13191.1 EEB08623.1 - 4.4e-06 26.7 3.1 0.048 13.6 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEB08623.1 - 5.6e-06 25.9 0.1 0.03 13.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EEB08623.1 - 6.4e-06 25.2 0.0 0.0046 15.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 EEB08623.1 - 4.6e-05 23.3 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.1 EEB08623.1 - 5.3e-05 23.3 1.8 0.83 9.7 0.5 3.7 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EEB08623.1 - 0.00029 21.6 0.3 0.33 11.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEB08623.1 - 0.00029 20.3 3.1 0.6 9.4 0.1 3.1 2 1 0 3 3 3 2 AAA-like domain MobB PF03205.9 EEB08623.1 - 0.00042 20.0 1.6 0.19 11.4 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEB08623.1 - 0.00046 19.4 0.1 0.099 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 EEB08623.1 - 0.00066 19.5 1.4 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 KaiC PF06745.8 EEB08623.1 - 0.0011 18.0 0.8 0.24 10.5 0.0 2.4 2 0 0 2 2 2 1 KaiC NACHT PF05729.7 EEB08623.1 - 0.0014 18.3 0.6 1.2 8.7 0.1 3.0 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EEB08623.1 - 0.0016 18.4 0.2 0.89 9.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EEB08623.1 - 0.0041 16.5 0.6 0.23 10.8 0.1 2.5 2 0 0 2 2 2 1 Ras family Septin PF00735.13 EEB08623.1 - 0.0057 15.7 0.1 0.63 8.9 0.0 2.4 2 0 0 2 2 2 1 Septin Pox_A32 PF04665.7 EEB08623.1 - 0.006 15.8 2.4 1.5 8.0 0.0 2.8 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_23 PF13476.1 EEB08623.1 - 0.008 16.5 1.0 1.8 8.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EEB08623.1 - 0.0084 15.7 1.1 0.63 9.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEB08623.1 - 0.015 14.3 0.2 4.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EEB08623.1 - 0.018 14.9 2.6 0.99 9.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEB08623.1 - 0.019 14.3 0.5 5.7 6.3 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_14 PF13173.1 EEB08623.1 - 0.019 14.8 0.2 14 5.5 0.0 4.1 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.1 EEB08623.1 - 0.044 13.5 0.6 6.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EEB08623.1 - 0.052 13.7 0.5 18 5.5 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 EEB08623.1 - 0.053 12.9 0.6 0.69 9.2 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SbcCD_C PF13558.1 EEB08623.1 - 0.073 13.0 0.1 18 5.3 0.0 3.6 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.4 EEB08623.1 - 0.078 11.9 0.3 0.58 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EEB08623.1 - 0.098 12.1 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EEB08623.1 - 0.11 12.2 0.9 8.3 6.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEB08623.1 - 0.12 11.8 0.3 19 4.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EEB08623.1 - 0.16 12.2 0.3 7.6 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Aldedh PF00171.17 EEB08624.1 - 5.8e-186 618.3 0.1 6.6e-186 618.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEB08624.1 - 0.00034 19.4 0.0 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EEB08624.1 - 0.15 11.2 0.0 8.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Bromodomain PF00439.20 EEB08625.2 - 3.3e-28 97.4 0.4 2.8e-22 78.4 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EEB08625.2 - 7.7e-20 70.8 0.1 1.8e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 BAH domain eIF2A PF08662.6 EEB08626.1 - 7.6e-79 263.9 0.3 5.4e-78 261.1 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEB08626.1 - 0.022 14.6 0.2 15 5.6 0.0 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat Clp1 PF06807.9 EEB08627.1 - 6.7e-12 45.5 0.0 2.3e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEB08627.1 - 3.3e-05 23.6 0.0 6.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEB08627.1 - 3.8e-05 24.5 0.0 9.6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEB08627.1 - 0.0018 18.4 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EEB08627.1 - 0.0024 18.0 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEB08627.1 - 0.0026 17.4 0.0 0.087 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEB08627.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EEB08627.1 - 0.012 14.6 0.0 0.032 13.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 EEB08627.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EEB08627.1 - 0.018 15.3 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEB08627.1 - 0.032 14.4 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEB08627.1 - 0.038 13.4 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 EEB08627.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EEB08627.1 - 0.056 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEB08627.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EEB08627.1 - 0.089 12.6 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEB08627.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EEB08627.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 EEB08627.1 - 0.14 11.7 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase Glyco_transf_34 PF05637.7 EEB08628.1 - 3.8e-77 259.0 0.9 4.6e-77 258.7 0.6 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EEB08628.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase EPL1 PF10513.4 EEB08630.2 - 3.7e-20 72.7 0.8 3.7e-20 72.7 0.6 1.9 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 EEB08631.1 - 4e-23 78.8 10.2 1.4e-06 27.1 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEB08631.1 - 8.4e-22 77.0 3.7 1.6e-12 47.3 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEB08631.1 - 7.9e-19 65.8 4.9 4.7e-05 22.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEB08631.1 - 1.8e-17 61.7 11.7 7.6e-05 21.8 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EEB08631.1 - 7.2e-13 47.9 11.2 0.00033 20.2 0.5 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEB08631.1 - 1.4e-07 31.5 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEB08631.1 - 0.00034 20.2 6.5 0.7 9.6 0.4 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand NLE PF08154.7 EEB08631.1 - 0.023 14.7 0.1 5 7.2 0.0 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain Anthrax-tox_M PF09156.5 EEB08631.1 - 0.062 12.4 0.4 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain DnaJ PF00226.26 EEB08632.1 - 1.2e-26 92.1 2.1 1.9e-26 91.5 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEB08632.1 - 5.3e-26 90.3 0.0 3.5e-22 78.1 0.0 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain TB2_DP1_HVA22 PF03134.14 EEB08633.2 - 5.5e-30 102.9 7.5 7.9e-30 102.4 5.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family OAD_gamma PF04277.8 EEB08633.2 - 0.0052 17.1 1.5 3.3 8.1 0.1 2.3 2 0 0 2 2 2 2 Oxaloacetate decarboxylase, gamma chain RNase_P_Rpp14 PF01900.14 EEB08634.1 - 9e-35 118.8 0.0 1e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family Ham1p_like PF01725.11 EEB08635.2 - 2.1e-52 177.2 0.0 2.3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EEB08636.1 - 1.5e-26 93.1 0.1 2.3e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB08636.1 - 1.1e-15 58.4 0.5 3e-15 57.0 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB08636.1 - 2.8e-07 30.5 0.0 1.8e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEB08636.1 - 3.8e-06 26.9 0.3 6e-06 26.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEB08636.1 - 1.3e-05 24.5 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.24 EEB08636.1 - 5.3e-05 23.4 0.0 0.00011 22.4 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB08636.1 - 0.00014 21.9 0.0 0.00032 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EEB08636.1 - 0.00014 21.7 0.1 0.0004 20.2 0.1 1.7 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.10 EEB08636.1 - 0.00017 21.3 0.0 0.00077 19.2 0.0 1.9 2 0 0 2 2 2 1 NTPase ADK PF00406.17 EEB08636.1 - 0.00034 20.5 0.0 0.015 15.1 0.0 2.2 1 1 0 2 2 2 1 Adenylate kinase AAA_5 PF07728.9 EEB08636.1 - 0.00044 19.9 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EEB08636.1 - 0.00087 18.8 0.0 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EEB08636.1 - 0.0011 18.8 0.0 0.0039 17.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEB08636.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 EEB08636.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EEB08636.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEB08636.1 - 0.0024 17.8 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EEB08636.1 - 0.0035 16.4 0.1 0.0095 15.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EEB08636.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EEB08636.1 - 0.0055 17.1 0.0 0.011 16.1 0.0 1.7 1 1 1 2 2 1 1 Miro-like protein Cytidylate_kin2 PF13189.1 EEB08636.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase-like family Thymidylate_kin PF02223.12 EEB08636.1 - 0.0065 15.8 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_25 PF13481.1 EEB08636.1 - 0.0074 15.7 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEB08636.1 - 0.0074 15.2 0.1 0.012 14.6 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EEB08636.1 - 0.0077 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 EEB08636.1 - 0.0097 14.5 0.0 0.017 13.7 0.0 1.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain KaiC PF06745.8 EEB08636.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.6 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EEB08636.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 EEB08636.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EEB08636.1 - 0.015 14.7 0.0 0.017 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EEB08636.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EEB08636.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.7 EEB08636.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EEB08636.1 - 0.029 13.7 0.1 0.063 12.7 0.0 1.5 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Parvo_NS1 PF01057.12 EEB08636.1 - 0.03 13.2 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 EEB08636.1 - 0.035 13.0 0.2 0.06 12.2 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.6 EEB08636.1 - 0.04 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EEB08636.1 - 0.045 14.0 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EEB08636.1 - 0.052 12.9 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 EEB08636.1 - 0.055 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EEB08636.1 - 0.08 12.1 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EEB08636.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EEB08636.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 EEB08637.1 - 9.3e-62 208.5 0.1 8.7e-61 205.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08637.1 - 8.2e-36 123.3 0.0 1.2e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEB08637.1 - 1.8e-12 46.8 0.0 1.1e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB08637.1 - 0.00051 19.8 0.2 0.0023 17.7 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB08637.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EEB08637.1 - 0.014 14.7 0.2 0.063 12.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF1296 PF06972.6 EEB08637.1 - 0.039 13.9 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) PIG-X PF08320.7 EEB08639.1 - 7.8e-39 133.1 0.7 1.6e-37 128.8 0.5 2.1 1 1 0 1 1 1 1 PIG-X / PBN1 AMPKBI PF04739.10 EEB08640.1 - 4.4e-27 93.9 0.2 4.4e-27 93.9 0.2 2.2 2 1 1 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain FAD-oxidase_C PF02913.14 EEB08642.1 - 2.2e-63 213.9 0.0 3.9e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEB08642.1 - 4.5e-39 133.0 0.1 8.6e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain TPR_11 PF13414.1 EEB08643.1 - 4.9e-45 151.0 47.6 4.8e-11 42.1 0.8 13.5 11 3 5 16 16 16 11 TPR repeat TPR_16 PF13432.1 EEB08643.1 - 5.7e-29 100.1 37.9 1.8e-08 34.7 0.3 12.7 10 3 3 14 14 14 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEB08643.1 - 2.6e-28 95.6 47.9 1.6e-05 24.4 0.3 17.0 18 1 0 18 18 17 8 Tetratricopeptide repeat TPR_1 PF00515.23 EEB08643.1 - 5.7e-28 95.3 28.3 5e-05 22.7 0.1 14.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08643.1 - 1.2e-23 83.1 25.8 6.2e-05 23.2 0.0 11.0 8 3 2 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08643.1 - 4e-20 70.4 43.8 0.0015 18.9 0.6 15.9 10 5 8 18 18 17 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEB08643.1 - 3.7e-19 66.9 25.9 0.093 12.5 0.0 14.0 13 1 1 14 14 14 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEB08643.1 - 4.1e-17 61.8 49.8 1.4e-05 24.9 0.8 12.0 8 5 7 15 15 14 9 Tetratricopeptide repeat TPR_17 PF13431.1 EEB08643.1 - 4.9e-15 54.3 31.6 0.22 11.8 0.0 15.3 18 0 0 18 18 15 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEB08643.1 - 3.3e-14 51.4 29.5 0.095 12.5 0.1 13.1 14 0 0 14 14 13 3 Tetratricopeptide repeat Apc3 PF12895.2 EEB08643.1 - 9.8e-11 41.6 36.6 5.3e-07 29.6 0.3 8.8 10 0 0 10 10 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EEB08643.1 - 2.7e-07 30.3 14.6 0.024 14.4 0.2 9.1 8 2 1 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEB08643.1 - 4.7e-05 23.1 14.0 0.67 9.9 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_20 PF14561.1 EEB08643.1 - 4.9e-05 23.3 14.2 0.73 9.9 0.0 7.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEB08643.1 - 0.00047 20.3 9.7 3.2 8.4 0.2 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEB08643.1 - 0.00098 19.4 22.1 60 4.4 0.0 12.4 15 0 0 15 15 13 0 Tetratricopeptide repeat BTAD PF03704.12 EEB08643.1 - 0.004 17.4 21.6 0.058 13.6 2.3 5.3 4 1 1 5 5 5 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EEB08643.1 - 2.1 8.2 14.3 6.9 6.6 0.1 6.5 7 1 1 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat DUF4398 PF14346.1 EEB08643.1 - 7.1 6.7 11.8 1 9.4 1.4 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF4398) SNF2_N PF00176.18 EEB08644.2 - 7.1e-82 274.5 0.2 7.1e-82 274.5 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEB08644.2 - 1.4e-22 79.3 0.8 4.2e-22 77.8 0.6 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EEB08644.2 - 2.6e-18 65.6 0.0 1.2e-16 60.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain QLQ PF08880.6 EEB08644.2 - 7e-16 57.3 2.0 2.2e-15 55.7 1.4 2.0 1 0 0 1 1 1 1 QLQ SnAC PF14619.1 EEB08644.2 - 2e-12 47.1 3.9 2.4e-12 46.8 0.7 2.7 1 1 1 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.10 EEB08644.2 - 1e-05 25.4 0.1 0.00012 21.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Shugoshin_C PF07557.6 EEB08644.2 - 0.028 13.9 0.3 0.062 12.7 0.2 1.6 1 0 0 1 1 1 0 Shugoshin C terminus PDT PF00800.13 EEB08644.2 - 0.3 10.6 4.8 5 6.6 0.7 2.8 2 0 0 2 2 2 0 Prephenate dehydratase His_Phos_1 PF00300.17 EEB08645.1 - 1.7e-24 86.6 0.0 2.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 EEB08646.2 - 2.4e-23 82.4 23.4 2.4e-23 82.4 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB08646.2 - 0.00016 20.4 10.3 0.00016 20.4 7.1 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter DUF3270 PF11674.3 EEB08646.2 - 1.9 8.5 0.0 1.9 8.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3270) WD40 PF00400.27 EEB08647.1 - 1.7e-13 49.8 6.5 9.4e-05 22.1 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EEB08647.1 - 9.4e-05 22.1 0.0 0.25 11.0 0.0 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EEB08647.1 - 0.023 13.8 0.1 0.13 11.3 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EEB08647.1 - 0.063 11.0 0.0 0.72 7.5 0.0 2.3 2 1 1 3 3 3 0 IKI3 family PPTA PF01239.17 EEB08648.2 - 8.7e-42 138.7 19.1 7.2e-09 34.6 0.1 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Pribosyltran_N PF13793.1 EEB08649.1 - 6.1e-50 167.8 0.3 1.1e-47 160.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEB08649.1 - 8e-47 159.3 4.1 2.4e-40 138.2 2.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEB08649.1 - 4.7e-14 52.1 1.2 2e-13 50.1 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEB08649.1 - 0.0026 16.9 0.2 0.0043 16.2 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EEB08649.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain DUF2296 PF10058.4 EEB08650.2 - 4.4e-17 61.5 0.6 8.3e-17 60.6 0.4 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) ATP-grasp_2 PF08442.5 EEB08651.2 - 4.4e-75 251.5 0.1 7.6e-75 250.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EEB08651.2 - 5.6e-24 84.4 0.3 9e-24 83.8 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EEB08651.2 - 0.0001 21.6 0.2 0.00037 19.7 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EEB08651.2 - 0.0013 18.3 0.0 0.0068 15.9 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EEB08651.2 - 0.011 15.2 0.0 0.27 10.6 0.0 2.5 2 1 0 2 2 2 0 RimK-like ATP-grasp domain Succ_CoA_lig PF13607.1 EEB08651.2 - 0.012 15.2 0.2 1.3 8.6 0.1 2.6 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EEB08651.2 - 0.051 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain HSP20 PF00011.16 EEB08653.1 - 3.8e-21 74.8 0.4 4.5e-21 74.6 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EEB08653.1 - 0.011 16.2 0.3 0.088 13.3 0.1 2.0 1 1 1 2 2 2 0 CS domain DUF4097 PF13349.1 EEB08653.1 - 0.013 15.0 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) BON PF04972.12 EEB08653.1 - 0.015 15.0 0.4 0.03 14.0 0.2 1.6 2 0 0 2 2 2 0 BON domain ComJ PF11033.3 EEB08653.1 - 0.018 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Competence protein J (ComJ) Lung_7-TM_R PF06814.8 EEB08654.1 - 1.2e-10 40.8 7.3 2.1e-10 40.0 5.1 1.4 1 1 1 2 2 2 1 Lung seven transmembrane receptor MFS_1 PF07690.11 EEB08655.1 - 9.8e-35 119.8 23.0 9.8e-35 119.8 15.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB08655.1 - 7.1e-09 34.7 24.1 4.7e-08 32.0 16.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EEB08655.1 - 0.00022 19.4 1.2 0.00038 18.7 0.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.11 EEB08655.1 - 0.0063 16.0 1.4 0.0063 16.0 1.0 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Aldose_epim PF01263.15 EEB08656.1 - 7.1e-67 225.6 0.2 1.1e-66 224.9 0.1 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EEB08656.1 - 1.1e-49 168.9 0.1 2.4e-49 167.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEB08656.1 - 1.2e-24 86.0 0.0 1.1e-23 82.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EEB08656.1 - 5.6e-16 58.0 0.1 1.1e-15 57.1 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEB08656.1 - 1.2e-15 57.2 0.0 2.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEB08656.1 - 8.4e-15 54.4 0.0 1.5e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEB08656.1 - 2.5e-09 37.4 0.0 4.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEB08656.1 - 1.4e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEB08656.1 - 2.1e-07 30.1 0.0 4.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 EEB08656.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEB08656.1 - 0.00016 21.0 0.5 0.00035 19.9 0.4 1.6 1 0 0 1 1 1 1 NmrA-like family DAO PF01266.19 EEB08656.1 - 0.0083 15.0 0.2 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EEB08656.1 - 0.029 13.7 0.4 0.054 12.8 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 EEB08657.1 - 1.5e-117 392.9 27.0 1.7e-117 392.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB08657.1 - 3.9e-21 75.1 29.8 2.3e-15 56.2 7.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EEB08658.1 - 8e-61 205.3 0.0 9.4e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-ADH PF00465.14 EEB08659.1 - 8.4e-123 409.6 5.7 9.5e-123 409.4 4.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEB08659.1 - 1.8e-27 96.2 6.7 4e-14 52.5 0.1 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Met_synt_B12 PF02965.12 EEB08659.1 - 0.087 12.0 0.3 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Glyco_hydro_31 PF01055.21 EEB08660.1 - 8.1e-165 548.9 8.7 1.1e-164 548.4 6.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEB08660.1 - 0.0061 16.3 1.6 0.014 15.2 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Methyltransf_31 PF13847.1 EEB08661.1 - 2.7e-32 111.4 0.0 3.6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB08661.1 - 7.1e-19 68.0 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08661.1 - 1.3e-17 64.3 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08661.1 - 1e-16 61.0 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB08661.1 - 2.8e-15 56.3 0.0 4.6e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08661.1 - 2.3e-14 53.6 0.0 3.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB08661.1 - 5.8e-12 45.6 0.0 1.8e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEB08661.1 - 7.7e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EEB08661.1 - 3.3e-11 42.8 0.0 5.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EEB08661.1 - 2e-09 36.9 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EEB08661.1 - 5.5e-09 35.5 0.0 7.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EEB08661.1 - 6e-09 35.2 0.0 8.9e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EEB08661.1 - 7.5e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 EEB08661.1 - 3.4e-07 29.8 0.0 5.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EEB08661.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 EEB08661.1 - 1.3e-06 27.6 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 EEB08661.1 - 7e-06 24.9 0.0 1.4e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) GidB PF02527.10 EEB08661.1 - 1.1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.5 EEB08661.1 - 2.8e-05 23.7 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NodS PF05401.6 EEB08661.1 - 6.1e-05 22.5 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EEB08661.1 - 0.00013 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EEB08661.1 - 0.00019 20.7 0.2 0.014 14.7 0.1 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain DREV PF05219.7 EEB08661.1 - 0.00058 18.8 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EEB08661.1 - 0.00067 18.7 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EEB08661.1 - 0.0009 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 EEB08661.1 - 0.0014 18.0 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EEB08661.1 - 0.0027 16.9 0.0 0.0033 16.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 EEB08661.1 - 0.0051 16.4 0.1 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein tRNA_U5-meth_tr PF05958.6 EEB08661.1 - 0.0079 14.9 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DUF938 PF06080.7 EEB08661.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EEB08661.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 EEB08661.1 - 0.028 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.10 EEB08661.1 - 0.046 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PA14_2 PF10528.4 EEB08662.1 - 4.5e-19 68.4 0.5 4.5e-19 68.4 0.3 2.4 2 0 0 2 2 2 1 GLEYA domain AA_permease PF00324.16 EEB08663.1 - 3.2e-108 362.1 40.5 4e-108 361.7 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB08663.1 - 7.2e-30 103.8 43.2 9.3e-30 103.5 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease Gp_dh_C PF02800.15 EEB08664.1 - 1.2e-74 248.9 0.1 1.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEB08664.1 - 1.3e-61 207.0 0.1 2.6e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EEB08664.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EEB08664.1 - 0.024 14.5 1.8 0.079 12.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EEB08664.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.16 EEB08665.1 - 3.5e-113 378.4 38.0 4.5e-113 378.1 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB08665.1 - 1.8e-33 115.7 40.7 2.4e-33 115.3 28.2 1.2 1 0 0 1 1 1 1 Amino acid permease zf-RING_2 PF13639.1 EEB08667.1 - 8.3e-16 57.5 10.1 1.3e-15 56.8 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEB08667.1 - 2.6e-11 43.4 4.8 4.7e-11 42.6 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEB08667.1 - 4.3e-07 29.8 8.8 6.9e-07 29.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEB08667.1 - 2.1e-06 27.4 1.8 4.5e-06 26.4 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EEB08667.1 - 1.3e-05 24.7 9.6 2.1e-05 24.1 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEB08667.1 - 1.4e-05 24.6 9.6 2.3e-05 23.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB08667.1 - 4e-05 23.2 6.9 5.9e-05 22.6 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EEB08667.1 - 0.037 13.5 3.6 0.067 12.7 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EEB08667.1 - 0.049 13.6 10.8 0.083 12.9 7.5 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EEB08667.1 - 0.25 11.0 6.5 0.76 9.5 4.5 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EEB08667.1 - 0.42 10.6 5.9 0.94 9.4 4.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EEB08667.1 - 0.88 9.6 9.0 1.5 8.8 6.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EEB08667.1 - 2.3 7.8 8.0 4.5 6.9 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEB08667.1 - 2.6 7.8 6.3 5.9 6.6 4.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEB08667.1 - 2.9 7.8 8.0 24 4.9 5.5 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SMC_N PF02463.14 EEB08668.1 - 1.2e-67 227.3 7.1 6.8e-67 224.9 4.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEB08668.1 - 2e-23 82.6 0.3 2.9e-21 75.6 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEB08668.1 - 6.9e-13 49.2 1.5 4.9e-07 30.0 0.1 3.9 4 1 0 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 EEB08668.1 - 7.6e-06 25.3 38.2 0.00012 21.4 1.8 5.0 3 2 2 5 5 5 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EEB08668.1 - 3.2e-05 23.3 0.0 8.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 EEB08668.1 - 0.0019 18.0 5.4 0.0019 18.0 3.8 8.2 4 2 4 8 8 8 2 Tropomyosin like AAA_23 PF13476.1 EEB08668.1 - 0.0025 18.1 45.7 0.0025 18.1 31.7 6.9 2 2 0 2 2 2 1 AAA domain FliJ PF02050.11 EEB08668.1 - 0.011 15.8 12.2 0.011 15.8 8.4 8.7 3 3 2 7 7 7 0 Flagellar FliJ protein Spc97_Spc98 PF04130.8 EEB08670.1 - 1.1e-121 406.8 8.7 1.4e-121 406.5 6.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Ran_BP1 PF00638.13 EEB08671.2 - 1.7e-19 70.0 0.2 4.3e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 RanBP1 domain Ax_dynein_light PF10211.4 EEB08671.2 - 0.71 9.6 11.9 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain YfhO PF09586.5 EEB08671.2 - 3.4 5.5 7.0 4.7 5.1 4.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ish1 PF10281.4 EEB08672.1 - 2.8e-47 158.3 37.4 1.6e-08 34.4 1.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EEB08672.1 - 8.4e-10 37.9 0.0 0.14 11.6 0.0 6.4 6 1 0 6 6 6 3 SAP domain HeH PF12949.2 EEB08672.1 - 2e-08 33.6 0.0 0.00037 19.9 0.0 5.2 6 0 0 6 6 6 1 HeH/LEM domain Phasin PF05597.6 EEB08672.1 - 2.4e-05 24.1 10.8 0.044 13.5 0.5 4.3 3 1 1 4 4 4 3 Poly(hydroxyalcanoate) granule associated protein (phasin) APC2 PF08672.6 EEB08672.1 - 0.0011 19.1 0.8 9.1 6.6 0.0 5.4 6 0 0 6 6 6 1 Anaphase promoting complex (APC) subunit 2 LEA_4 PF02987.11 EEB08672.1 - 0.0012 18.7 4.1 0.0012 18.7 2.8 3.4 3 0 0 3 3 3 1 Late embryogenesis abundant protein DUF883 PF05957.8 EEB08672.1 - 0.027 14.8 18.4 0.58 10.5 2.0 5.0 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) RsbRD_N PF14361.1 EEB08672.1 - 0.028 14.8 2.9 1.1 9.6 0.4 3.7 3 1 1 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Thioredoxin_6 PF13848.1 EEB08672.1 - 0.033 13.9 5.7 1.8 8.3 0.0 4.4 3 1 1 5 5 5 0 Thioredoxin-like domain ApoO PF09769.4 EEB08672.1 - 0.17 11.6 4.0 3 7.5 0.0 4.0 2 1 3 5 5 5 0 Apolipoprotein O YtxH PF12732.2 EEB08672.1 - 0.61 10.4 21.7 0.81 10.1 0.5 5.4 3 1 1 4 4 4 0 YtxH-like protein SAM_2 PF07647.12 EEB08672.1 - 5.4 6.9 6.9 29 4.5 0.2 4.6 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) GRIP PF01465.15 EEB08673.1 - 1.9e-11 43.3 0.1 4.1e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 GRIP domain HalX PF08663.5 EEB08673.1 - 0.03 14.3 9.2 0.039 13.9 2.0 2.7 1 1 1 2 2 2 0 HalX domain AAA_32 PF13654.1 EEB08673.1 - 0.066 11.8 10.3 0.091 11.4 7.1 1.2 1 0 0 1 1 1 0 AAA domain DUF465 PF04325.8 EEB08673.1 - 0.1 12.3 4.2 0.1 12.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF1875 PF08961.5 EEB08673.1 - 0.38 10.0 10.3 0.021 14.1 1.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1875) SlyX PF04102.7 EEB08673.1 - 0.68 10.3 7.5 7.4 7.0 0.5 2.9 1 1 1 2 2 2 0 SlyX NYD-SP28_assoc PF14775.1 EEB08673.1 - 1.6 8.4 6.7 1.1 8.9 1.9 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain V_ATPase_I PF01496.14 EEB08673.1 - 2.2 6.0 15.3 2.8 5.6 10.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mto2_bdg PF12808.2 EEB08673.1 - 2.7 8.1 10.9 0.5 10.5 1.5 3.4 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIVA PF05103.8 EEB08673.1 - 3.5 7.6 24.3 0.36 10.9 5.1 2.4 1 1 1 2 2 2 0 DivIVA protein DUF2664 PF10867.3 EEB08673.1 - 4.2 8.0 8.1 6.7 7.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) TPR_MLP1_2 PF07926.7 EEB08673.1 - 4.3 7.0 23.6 0.12 12.0 5.5 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Actin PF00022.14 EEB08674.1 - 1.7e-70 237.4 0.0 2.6e-36 124.8 0.0 2.9 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.8 EEB08674.1 - 0.039 12.5 0.0 0.1 11.1 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Kin17_mid PF10357.4 EEB08675.1 - 3.6e-52 175.3 2.9 6.1e-52 174.5 2.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EEB08675.1 - 0.00019 21.5 3.9 0.00041 20.4 2.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEB08675.1 - 0.00043 20.3 2.9 0.0011 19.0 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding HCV_NS5a_1b PF08301.8 EEB08675.1 - 0.012 15.8 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b Ribosomal_S10 PF00338.17 EEB08675.1 - 0.05 13.4 1.8 0.66 9.8 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e zf-C2H2_2 PF12756.2 EEB08675.1 - 0.48 10.5 9.6 0.16 12.1 1.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EEB08675.1 - 1.2 8.9 7.0 0.24 11.1 2.0 2.0 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DER1 PF04511.10 EEB08676.1 - 4.3e-34 117.7 11.0 5.1e-34 117.4 7.6 1.0 1 0 0 1 1 1 1 Der1-like family DUF1352 PF07086.7 EEB08676.1 - 0.26 10.8 3.5 0.17 11.4 1.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1352) TMF_TATA_bd PF12325.3 EEB08677.1 - 7.4e-32 109.6 56.5 2.5e-30 104.6 10.7 4.6 3 2 1 4 4 4 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEB08677.1 - 2.1e-15 56.2 8.4 2.1e-15 56.2 5.8 6.5 3 3 3 6 6 6 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EEB08677.1 - 3.7e-05 22.4 0.4 3.7e-05 22.4 0.3 2.6 2 1 0 2 2 2 1 AAA domain IncA PF04156.9 EEB08677.1 - 0.00074 19.1 54.0 0.023 14.3 6.9 4.0 2 1 2 4 4 4 4 IncA protein ATG16 PF08614.6 EEB08677.1 - 0.004 17.0 9.4 0.004 17.0 6.5 4.7 2 2 3 5 5 5 2 Autophagy protein 16 (ATG16) HlyE PF06109.8 EEB08677.1 - 0.0048 15.9 1.4 0.0048 15.9 1.0 2.1 2 1 0 2 2 2 1 Haemolysin E (HlyE) Rootletin PF15035.1 EEB08677.1 - 0.0049 16.8 45.8 0.14 12.0 9.2 3.4 2 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 EEB08677.1 - 0.0064 16.0 45.5 0.47 9.8 6.2 3.3 2 1 1 3 3 3 3 Intermediate filament protein DUF869 PF05911.6 EEB08677.1 - 0.018 13.3 42.7 0.077 11.2 2.1 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) GAS PF13851.1 EEB08677.1 - 0.091 11.9 54.8 0.61 9.2 6.0 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EEB08677.1 - 0.1 12.4 64.1 0.57 10.0 10.5 4.3 2 1 1 3 3 3 0 Tropomyosin like Phage_GP20 PF06810.6 EEB08677.1 - 0.28 10.6 48.2 0.075 12.4 4.7 5.2 2 2 3 5 5 5 0 Phage minor structural protein GP20 DivIC PF04977.10 EEB08677.1 - 1 8.9 55.6 2 7.9 5.1 6.7 3 2 1 6 6 6 0 Septum formation initiator Mnd1 PF03962.10 EEB08677.1 - 1.9 8.0 53.1 0.48 10.0 9.5 3.7 2 1 3 5 5 5 0 Mnd1 family ADIP PF11559.3 EEB08677.1 - 2 8.3 62.6 2 8.3 3.8 6.5 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 EEB08677.1 - 5.4 5.3 54.0 0.087 11.2 9.1 3.5 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Rad60-SLD PF11976.3 EEB08678.1 - 2.6e-24 84.6 0.1 3.3e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEB08678.1 - 8.1e-10 37.9 0.1 1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Hist_deacetyl PF00850.14 EEB08679.1 - 2.9e-91 306.0 0.0 4.4e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EEB08679.1 - 1.1e-38 132.4 0.0 1.8e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Whi5 PF08528.6 EEB08680.1 - 1.1e-08 34.4 0.3 3e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 Whi5 like DUF4410 PF14366.1 EEB08680.1 - 0.055 13.2 0.1 0.11 12.1 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) DUF663 PF04950.7 EEB08681.1 - 1.7e-94 316.1 0.1 1.7e-94 316.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEB08681.1 - 7.6e-31 105.4 0.0 2.2e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EEB08681.1 - 8.5e-08 31.8 0.2 2.8e-05 23.6 0.0 2.8 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEB08681.1 - 1.2e-05 25.4 0.0 5e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEB08681.1 - 9.7e-05 22.3 0.0 0.00031 20.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EEB08681.1 - 0.00017 21.7 0.2 0.00049 20.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EEB08681.1 - 0.00037 19.9 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EEB08681.1 - 0.00044 20.5 0.0 0.0021 18.3 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EEB08681.1 - 0.00063 20.5 0.0 0.00063 20.5 0.0 4.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EEB08681.1 - 0.0011 18.8 0.0 0.0011 18.8 0.0 2.7 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EEB08681.1 - 0.0011 18.9 1.3 0.0022 17.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.1 EEB08681.1 - 0.0019 17.9 1.7 0.0041 16.8 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 EEB08681.1 - 0.0026 18.2 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EEB08681.1 - 0.0028 17.3 0.4 0.0089 15.7 0.3 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEB08681.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 EEB08681.1 - 0.023 14.6 3.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEB08681.1 - 0.03 14.5 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 EEB08681.1 - 0.038 14.2 0.0 0.038 14.2 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EEB08681.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEB08681.1 - 0.048 13.3 0.4 0.14 11.8 0.3 1.8 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EEB08681.1 - 0.055 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EEB08681.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EEB08681.1 - 0.088 12.2 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EEB08681.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 EEB08681.1 - 0.28 9.9 0.0 0.28 9.9 0.0 2.1 3 0 0 3 3 3 0 ArgK protein AAA_11 PF13086.1 EEB08681.1 - 0.49 9.9 0.0 0.49 9.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain GLE1 PF07817.8 EEB08682.1 - 2.7e-67 226.3 2.0 2.7e-67 226.3 1.4 2.2 2 0 0 2 2 2 1 GLE1-like protein CAF-1_p150 PF11600.3 EEB08682.1 - 0.0023 17.3 42.7 0.0054 16.1 29.6 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 EEB08682.1 - 0.088 11.2 35.4 0.12 10.8 24.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 EEB08682.1 - 2 6.9 9.2 2.7 6.4 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 EEB08682.1 - 2.8 6.1 37.8 7.8 4.6 25.4 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 EEB08682.1 - 5.3 6.8 27.2 7.8 6.2 18.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FMN_dh PF01070.13 EEB08682.1 - 6.4 5.5 12.0 9.1 5.0 6.8 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase SNARE PF05739.14 EEB08683.1 - 4.8e-16 58.1 2.3 4.8e-16 58.1 1.6 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EEB08683.1 - 3.6e-11 42.9 3.7 3.6e-11 42.9 2.6 2.6 2 1 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 EEB08683.1 - 0.017 14.6 2.5 0.017 14.6 1.7 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.8 EEB08683.1 - 0.08 12.0 3.1 0.081 11.9 1.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein Herpes_US9 PF06072.6 EEB08683.1 - 0.11 12.3 1.1 0.21 11.4 0.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 T2SF PF00482.18 EEB08683.1 - 0.19 11.6 4.1 1.4 8.8 0.3 2.7 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein F Acyl-CoA_dh_2 PF08028.6 EEB08683.1 - 1.3 9.3 5.2 0.77 10.0 1.1 2.3 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1664 PF07889.7 EEB08683.1 - 4.3 7.1 6.5 8.1 6.2 1.6 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) ubiquitin PF00240.18 EEB08684.1 - 4.3e-06 26.0 0.0 7.4e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EEB08684.1 - 0.00013 22.1 0.0 0.00085 19.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EEB08684.1 - 0.065 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like E1-E2_ATPase PF00122.15 EEB08685.1 - 2.3e-80 268.9 1.3 2.3e-80 268.9 0.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEB08685.1 - 6.6e-49 165.9 3.0 6.6e-49 165.9 2.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEB08685.1 - 1.1e-28 101.1 0.0 3.4e-28 99.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB08685.1 - 2.5e-18 65.8 0.0 4.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEB08685.1 - 1.4e-16 61.2 0.0 6.1e-16 59.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEB08685.1 - 3.3e-15 55.3 0.0 9.6e-15 53.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEB08685.1 - 1.4e-06 28.0 0.7 8.7e-05 22.2 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.2 EEB08685.1 - 0.0047 16.8 0.5 2.3 8.2 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3784) RseC_MucC PF04246.7 EEB08685.1 - 0.61 9.6 4.0 0.74 9.3 0.0 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ATG_C PF09333.6 EEB08686.1 - 2.7e-21 75.5 0.0 5.6e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain ATG2_CAD PF13329.1 EEB08686.1 - 1.1e-11 44.4 0.1 4.8e-11 42.4 0.1 2.1 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.2 EEB08686.1 - 1e-08 34.7 0.1 3.1e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter 6PGD PF00393.14 EEB08687.2 - 2.6e-131 437.1 0.0 3.2e-131 436.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEB08687.2 - 2.2e-50 170.6 0.0 3.3e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEB08687.2 - 0.042 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Ub-Mut7C PF14451.1 EEB08687.2 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin RRM_1 PF00076.17 EEB08688.2 - 5e-39 131.7 0.1 3.2e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08688.2 - 1e-32 111.8 0.1 4.1e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08688.2 - 5e-14 51.8 0.0 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08688.2 - 0.00025 20.7 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.8 EEB08688.2 - 0.0038 17.2 0.0 22 5.2 0.0 3.4 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 EEB08688.2 - 0.012 15.4 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Senescence_reg PF04520.8 EEB08688.2 - 2.2 8.7 9.7 0.87 10.0 5.0 1.5 2 0 0 2 2 2 0 Senescence regulator DUF2201_N PF13203.1 EEB08688.2 - 4.1 6.4 8.8 6.4 5.8 6.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pkinase PF00069.20 EEB08689.1 - 1.2e-44 152.4 0.0 1.7e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08689.1 - 6.8e-26 90.8 0.0 9.7e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08689.1 - 0.0075 15.2 0.1 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PIP49_C PF12260.3 EEB08689.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Rep_fac-A_C PF08646.5 EEB08690.1 - 3.3e-53 179.3 3.5 4.1e-51 172.5 0.4 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EEB08690.1 - 2e-29 101.3 0.3 1.9e-28 98.2 0.1 2.3 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EEB08690.1 - 1.4e-16 60.1 1.1 5.9e-14 51.6 0.1 3.1 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EEB08690.1 - 1.4e-05 25.1 1.1 5.7e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF223 IBR PF01485.16 EEB08690.1 - 0.033 14.0 0.9 0.067 13.0 0.6 1.4 1 0 0 1 1 1 0 IBR domain zinc-ribbons_6 PF07191.7 EEB08690.1 - 0.17 11.7 3.5 0.14 11.9 1.2 1.8 2 0 0 2 2 2 0 zinc-ribbons zf-AN1 PF01428.11 EEB08690.1 - 0.17 11.8 1.4 0.29 11.0 1.0 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger Aminotran_5 PF00266.14 EEB08691.1 - 8.5e-27 93.8 0.0 1.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEB08691.1 - 2.8e-05 22.5 0.0 4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEB08691.1 - 4.6e-05 22.5 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.14 EEB08691.1 - 0.026 12.8 0.0 0.079 11.3 0.0 1.7 2 0 0 2 2 2 0 Serine hydroxymethyltransferase PDCD2_C PF04194.8 EEB08692.2 - 9.1e-32 109.9 1.3 1.3e-31 109.4 0.9 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain WD40 PF00400.27 EEB08693.1 - 2.6e-18 65.1 6.1 2.1e-06 27.3 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_S6e PF01092.14 EEB08694.1 - 3.3e-64 214.2 0.1 7.2e-64 213.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e HECT PF00632.20 EEB08695.1 - 2.3e-89 299.7 1.8 2e-88 296.6 0.1 2.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EEB08695.1 - 3.2e-43 147.9 16.0 8.8e-42 143.1 1.2 3.8 4 1 1 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EEB08695.1 - 3e-38 131.9 6.8 3e-38 131.9 4.7 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EEB08695.1 - 3.9e-08 33.1 0.0 1.3e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) GDC-P PF02347.11 EEB08696.1 - 1.6e-195 649.7 1.2 7.9e-181 601.4 0.0 3.5 2 1 1 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EEB08696.1 - 8.8e-10 37.8 0.2 1.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEB08696.1 - 3.3e-06 26.4 0.0 6.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Frataxin_Cyay PF01491.11 EEB08697.1 - 1.1e-34 118.4 0.0 1.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Med14 PF08638.6 EEB08697.1 - 0.032 13.4 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 GST_C PF00043.20 EEB08698.2 - 3.7e-10 39.6 0.2 6.9e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEB08698.2 - 3.8e-09 36.5 0.0 6.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEB08698.2 - 5.5e-07 29.9 0.1 9.3e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEB08698.2 - 6.7e-07 29.1 0.4 1.7e-06 27.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEB08698.2 - 0.0028 17.8 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Sec15 PF04091.7 EEB08699.2 - 1.6e-69 234.6 2.9 1.6e-69 234.6 2.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 EEB08699.2 - 7.7e-08 32.0 4.0 7.7e-08 32.0 2.8 2.5 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF4200 PF13863.1 EEB08699.2 - 0.04 13.8 5.6 0.13 12.1 3.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 EEB08699.2 - 0.083 12.4 6.0 0.24 10.9 4.2 1.7 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EEB08699.2 - 0.55 10.0 7.5 0.045 13.5 1.4 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF410 PF04190.8 EEB08700.1 - 6.6e-57 193.0 0.5 7.7e-57 192.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) P5-ATPase PF12409.3 EEB08701.1 - 7.2e-35 119.4 0.2 2e-34 118.0 0.2 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EEB08701.1 - 5.5e-28 97.5 0.0 1.5e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EEB08701.1 - 2.7e-24 86.4 0.0 4.9e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB08701.1 - 1.5e-14 54.9 0.0 3.8e-13 50.3 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB08701.1 - 8.1e-06 25.7 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEB08701.1 - 2e-05 23.9 0.0 4.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEB08701.1 - 0.047 13.2 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EEB08702.2 - 1e-35 120.3 6.5 5.3e-09 35.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEB08702.2 - 1.7e-27 95.1 0.2 4.1e-27 93.8 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TatD_DNase PF01026.16 EEB08703.2 - 2.1e-37 128.7 0.0 2.9e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SET PF00856.23 EEB08704.1 - 1.9e-10 41.2 1.3 5e-10 39.9 0.9 1.7 1 1 0 1 1 1 1 SET domain RP-C_C PF11800.3 EEB08704.1 - 0.09 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Glyco_transf_34 PF05637.7 EEB08705.1 - 1.2e-77 260.6 0.1 1.4e-77 260.4 0.1 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family KH_1 PF00013.24 EEB08706.1 - 0.0019 17.7 0.5 0.0048 16.5 0.3 1.6 1 0 0 1 1 1 1 KH domain DUF1640 PF07798.6 EEB08707.1 - 1.8e-43 148.6 2.8 2e-43 148.4 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) XhlA PF10779.4 EEB08707.1 - 0.0058 16.5 2.2 0.26 11.2 1.5 2.7 1 1 0 1 1 1 1 Haemolysin XhlA Reo_sigmaC PF04582.7 EEB08707.1 - 0.091 11.9 0.9 0.12 11.5 0.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EEB08707.1 - 0.27 11.0 1.4 0.79 9.5 0.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Remorin_C PF03763.8 EEB08707.1 - 0.53 9.8 3.4 0.86 9.1 2.3 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region Adeno_PIX PF03955.9 EEB08707.1 - 0.7 10.4 2.5 0.6 10.6 0.1 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 EEB08707.1 - 6.6 6.2 11.6 19 4.7 8.0 1.7 1 1 0 1 1 1 0 IncA protein RNB PF00773.14 EEB08710.1 - 3.2e-94 315.8 0.0 5e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain DUF4340 PF14238.1 EEB08710.1 - 0.0087 15.7 0.4 1 9.0 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4340) OB_RNB PF08206.6 EEB08710.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Nol1_Nop2_Fmu PF01189.12 EEB08711.1 - 3.7e-27 95.4 0.0 1e-26 93.9 0.0 1.7 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EEB08711.1 - 0.00012 21.7 0.1 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08711.1 - 0.0057 17.2 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEB08711.1 - 0.033 13.2 0.0 0.075 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Glyco_transf_22 PF03901.12 EEB08712.1 - 1.2e-59 202.3 31.6 1.6e-59 202.0 21.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-C2H2 PF00096.21 EEB08713.1 - 2.1e-13 49.7 14.8 2.3e-06 27.6 0.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEB08713.1 - 1.2e-11 44.2 13.3 9e-07 28.8 0.8 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEB08713.1 - 7.9e-09 35.2 14.3 0.00038 20.5 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EEB08713.1 - 0.0014 18.7 11.2 0.5 10.6 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEB08713.1 - 0.0028 17.7 9.5 1.2 9.3 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 EEB08713.1 - 0.11 12.4 7.4 1.2 9.1 4.5 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 EEB08713.1 - 3.7 7.4 6.3 1.1 9.1 1.9 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PfkB PF00294.19 EEB08714.1 - 2.1e-11 43.5 0.0 2.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PNP_UDP_1 PF01048.15 EEB08715.1 - 2.1e-36 125.0 0.0 2.6e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NMD3 PF04981.8 EEB08716.2 - 1.8e-62 210.5 7.1 6.9e-61 205.3 2.7 2.1 1 1 1 2 2 2 2 NMD3 family GcpE PF04551.9 EEB08716.2 - 0.017 13.9 0.1 0.027 13.2 0.1 1.2 1 0 0 1 1 1 0 GcpE protein DZR PF12773.2 EEB08716.2 - 0.035 13.9 7.0 0.11 12.3 2.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EEB08717.1 - 6.9e-21 73.5 12.3 6.9e-21 73.5 8.5 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EEB08717.1 - 1.1e-06 28.1 0.0 2.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08717.1 - 0.00024 20.8 0.0 0.00065 19.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EEB08717.1 - 0.0011 18.6 3.2 0.0011 18.6 2.2 2.0 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 EEB08717.1 - 0.0052 16.7 12.3 0.0052 16.7 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EEB08717.1 - 0.0091 15.2 2.2 0.016 14.4 1.5 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 EEB08717.1 - 0.012 15.3 4.1 0.025 14.2 2.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 EEB08717.1 - 0.068 13.1 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 EEB08718.1 - 7.1e-13 48.0 7.0 7.1e-13 48.0 4.9 2.5 2 0 0 2 2 2 1 PHD-finger zf-TAZ PF02135.11 EEB08718.1 - 0.0056 16.6 3.0 0.013 15.5 2.1 1.6 1 0 0 1 1 1 1 TAZ zinc finger C1_1 PF00130.17 EEB08718.1 - 0.38 10.5 23.0 0.33 10.7 1.1 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EEB08718.1 - 0.51 10.5 12.2 0.38 10.9 1.9 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain Cript PF10235.4 EEB08718.1 - 0.92 9.9 0.0 0.92 9.9 0.0 3.1 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT FYVE_2 PF02318.11 EEB08718.1 - 7.4 6.4 7.8 0.96 9.3 0.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Fic_N PF13784.1 EEB08719.1 - 0.84 9.5 4.6 0.61 9.9 1.7 1.8 2 0 0 2 2 2 0 Fic/DOC family N-terminal UPF1_Zn_bind PF09416.5 EEB08720.1 - 3.5e-70 234.4 3.5 7.4e-70 233.4 2.4 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EEB08720.1 - 2.6e-59 199.9 0.0 5.8e-59 198.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEB08720.1 - 5.8e-54 183.1 1.0 9.5e-54 182.4 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB08720.1 - 1.6e-15 56.5 0.5 4.6e-15 55.1 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEB08720.1 - 6.7e-15 55.1 0.5 1.5e-13 50.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEB08720.1 - 8.1e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEB08720.1 - 1.7e-06 27.2 0.4 3.5e-05 22.9 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EEB08720.1 - 3.7e-05 23.1 0.1 0.0013 18.1 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EEB08720.1 - 0.0014 18.3 0.1 0.0032 17.1 0.0 1.7 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 EEB08720.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEB08720.1 - 0.021 14.3 0.3 0.058 12.8 0.2 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 EEB08720.1 - 0.023 14.6 0.1 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EEB08720.1 - 0.027 14.6 0.1 0.092 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EEB08720.1 - 0.028 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 EEB08720.1 - 0.034 13.3 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.1 EEB08720.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 EEB08720.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ribosomal_S13_N PF08069.7 EEB08720.1 - 0.094 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.24 EEB08720.1 - 0.095 12.8 0.2 0.22 11.7 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEB08720.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EEB08720.1 - 0.1 11.7 0.0 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 EEB08720.1 - 0.13 11.0 0.1 0.46 9.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PIF1 PF05970.9 EEB08720.1 - 0.15 11.0 0.1 11 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Pkinase PF00069.20 EEB08721.2 - 3.8e-54 183.5 0.0 5.9e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08721.2 - 1.4e-24 86.5 0.0 5.5e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEB08721.2 - 0.00017 21.3 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Urb2 PF10441.4 EEB08722.1 - 1.1e-33 116.7 1.2 1.1e-33 116.7 0.8 3.3 4 0 0 4 4 4 1 Urb2/Npa2 family Sec1 PF00995.18 EEB08723.1 - 1.1e-139 466.7 5.2 1.2e-139 466.5 3.6 1.0 1 0 0 1 1 1 1 Sec1 family KRAB PF01352.22 EEB08723.1 - 0.0083 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 KRAB box G-patch PF01585.18 EEB08724.1 - 7.4e-09 35.2 0.2 1.4e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 G-patch domain BRO1 PF03097.13 EEB08725.1 - 2e-55 188.1 10.6 2e-55 188.1 7.4 2.3 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEB08725.1 - 1.3e-34 119.4 23.9 2e-34 118.9 15.9 1.8 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV A_deaminase_N PF08451.6 EEB08725.1 - 0.06 13.3 0.3 0.06 13.3 0.2 2.3 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal AAA PF00004.24 EEB08726.1 - 2e-44 150.9 0.0 3.9e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEB08726.1 - 2e-28 98.0 0.1 1.4e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EEB08726.1 - 2e-22 78.8 3.7 4.5e-22 77.7 2.6 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EEB08726.1 - 1.9e-06 28.7 0.1 6.1e-06 27.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EEB08726.1 - 2e-06 27.9 0.6 0.00062 19.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEB08726.1 - 2.4e-06 27.1 0.4 0.026 13.9 0.2 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EEB08726.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEB08726.1 - 1.8e-05 24.5 0.0 6.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEB08726.1 - 3.1e-05 23.4 0.0 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEB08726.1 - 3.9e-05 23.7 0.2 0.001 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EEB08726.1 - 4e-05 23.5 0.1 0.0002 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEB08726.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEB08726.1 - 0.00023 21.1 0.0 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEB08726.1 - 0.00034 19.6 0.0 0.00061 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EEB08726.1 - 0.0011 17.7 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EEB08726.1 - 0.0032 17.6 0.1 0.012 15.7 0.0 2.1 3 0 0 3 3 1 1 RNA helicase AAA_18 PF13238.1 EEB08726.1 - 0.0049 17.1 0.3 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EEB08726.1 - 0.0055 15.8 0.1 1.5 7.8 0.0 2.4 1 1 1 2 2 2 1 KaiC Zeta_toxin PF06414.7 EEB08726.1 - 0.0099 14.9 0.1 0.57 9.2 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EEB08726.1 - 0.014 14.9 0.1 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEB08726.1 - 0.015 14.9 0.1 1.1 8.9 0.0 2.3 1 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EEB08726.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EEB08726.1 - 0.022 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EEB08726.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EEB08726.1 - 0.063 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEB08726.1 - 0.066 12.6 0.8 0.73 9.2 0.0 2.7 3 1 1 4 4 4 0 AAA-like domain Arch_ATPase PF01637.13 EEB08726.1 - 0.14 11.8 1.2 0.73 9.4 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 EEB08726.1 - 0.16 11.2 2.4 0.2 10.8 0.1 2.2 2 1 0 2 2 2 0 PhoH-like protein PPV_E1_C PF00519.12 EEB08726.1 - 0.25 9.9 1.6 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_21 PF13304.1 EEB08726.1 - 0.57 10.0 4.5 3 7.7 0.5 3.0 2 1 0 2 2 2 0 AAA domain TPR_8 PF13181.1 EEB08726.1 - 1.2 9.0 5.0 1.6 8.7 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.16 EEB08727.1 - 7.4e-84 281.1 0.0 1.1e-83 280.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEB08727.1 - 0.0021 17.4 0.0 0.0059 16.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C CUB PF00431.15 EEB08727.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 CUB domain SMN PF06003.7 EEB08728.1 - 1.4e-05 24.3 9.9 1.4e-05 24.3 3.1 2.3 1 1 2 3 3 3 3 Survival motor neuron protein (SMN) DUF221 PF02714.10 EEB08729.2 - 1.3e-97 326.5 25.3 1.3e-97 326.5 17.6 1.8 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEB08729.2 - 2.1e-32 111.8 6.4 2.1e-32 111.8 4.5 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEB08729.2 - 4.6e-17 62.3 0.1 7.7e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EEB08729.2 - 0.00042 20.2 0.1 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08729.2 - 0.014 15.1 0.3 0.31 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.16 EEB08730.1 - 3.9e-41 140.0 0.1 6.3e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EEB08730.1 - 2.1e-27 94.5 0.1 4.1e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EEB08730.1 - 3.4e-07 30.5 0.0 1.2e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 EEB08730.1 - 5.9e-05 23.1 0.1 0.0086 16.1 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEB08730.1 - 0.034 14.4 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 EEB08730.1 - 0.068 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HA2 PF04408.18 EEB08731.1 - 6e-23 80.8 0.0 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEB08731.1 - 2.8e-22 78.6 0.1 6e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEB08731.1 - 1.3e-14 53.7 0.0 1.1e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08731.1 - 5.8e-08 32.4 0.0 1.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB08731.1 - 0.00018 21.6 0.0 0.00096 19.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EEB08731.1 - 0.0035 17.2 0.1 0.071 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEB08731.1 - 0.006 16.3 0.0 0.35 10.5 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 EEB08731.1 - 0.0082 15.0 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EEB08731.1 - 0.0097 15.0 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EEB08731.1 - 0.01 15.3 0.0 0.04 13.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEB08731.1 - 0.015 15.5 0.0 0.11 12.7 0.0 2.3 1 1 1 2 2 2 0 ABC transporter T2SE PF00437.15 EEB08731.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EEB08731.1 - 0.023 14.5 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEB08731.1 - 0.024 14.3 0.0 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EEB08731.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF258 PF03193.11 EEB08731.1 - 0.049 12.8 0.0 0.097 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEB08731.1 - 0.094 12.6 1.1 4.1 7.3 0.0 3.5 3 1 0 3 3 3 0 AAA ATPase domain DEAD PF00270.24 EEB08732.1 - 1.9e-23 82.7 0.0 8.6e-22 77.4 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08732.1 - 3.3e-20 71.7 0.0 2.4e-17 62.5 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EEB08732.1 - 3.5e-17 62.0 0.1 1.4e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 EEB08732.1 - 6e-15 54.7 0.1 1.5e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ATG22 PF11700.3 EEB08733.1 - 1.2e-87 294.4 24.8 1.4e-87 294.2 17.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EEB08733.1 - 0.00041 19.1 44.7 0.0015 17.3 0.9 3.8 2 1 2 4 4 4 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 EEB08733.1 - 0.098 11.6 0.1 0.098 11.6 0.1 2.5 3 0 0 3 3 3 0 E1-E2 ATPase DUF3591 PF12157.3 EEB08734.2 - 4.2e-194 645.1 1.0 7.8e-194 644.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EEB08734.2 - 2.5e-05 23.8 1.8 6.2e-05 22.5 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EEB08734.2 - 0.007 16.2 1.2 0.014 15.2 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_15 PF09445.5 EEB08735.1 - 1.5e-42 144.9 0.0 2e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EEB08735.1 - 2.8e-09 37.0 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB08735.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EEB08735.1 - 0.00035 20.2 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EEB08735.1 - 0.00048 20.4 0.0 0.0008 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EEB08735.1 - 0.0058 15.7 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_18 PF12847.2 EEB08735.1 - 0.0063 17.0 0.0 0.0089 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EEB08735.1 - 0.048 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_11 PF08241.7 EEB08735.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Gp_dh_C PF02800.15 EEB08736.1 - 1.2e-74 248.9 0.1 1.7e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEB08736.1 - 1.3e-61 207.0 0.1 2.6e-61 206.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EEB08736.1 - 0.0053 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EEB08736.1 - 0.024 14.5 1.8 0.079 12.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EEB08736.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FKBP_C PF00254.23 EEB08737.1 - 4.7e-29 100.2 0.1 1.2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIF_alpha PF05793.7 EEB08737.1 - 0.0019 16.6 31.3 0.0019 16.6 21.7 1.4 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PLRV_ORF5 PF01690.12 EEB08737.1 - 0.23 10.5 15.3 0.35 9.9 10.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 EEB08737.1 - 0.44 8.9 21.9 0.67 8.3 15.2 1.2 1 0 0 1 1 1 0 Daxx Family HGTP_anticodon2 PF12745.2 EEB08737.1 - 2.1 7.4 16.5 0.22 10.6 8.3 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Utp14 PF04615.8 EEB08737.1 - 3.7 5.5 29.6 0.11 10.6 15.6 1.8 2 0 0 2 2 2 0 Utp14 protein Peptidase_S30 PF01577.11 EEB08737.1 - 5.1 6.4 8.4 7.7 5.8 5.8 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Nucleoplasmin PF03066.10 EEB08737.1 - 9.5 5.7 35.1 2.5 7.6 16.3 3.5 1 1 1 2 2 2 0 Nucleoplasmin DUF572 PF04502.8 EEB08737.1 - 9.6 5.3 21.7 17 4.5 15.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) IMS PF00817.15 EEB08738.1 - 2.1e-39 134.7 0.0 6.7e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EEB08738.1 - 2.6e-12 46.7 0.1 6.2e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EEB08738.1 - 1.1e-05 25.3 7.3 0.0035 17.2 1.0 3.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EEB08738.1 - 8.4e-05 22.6 0.0 0.00031 20.8 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EEB08738.1 - 0.028 14.4 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif DUF3926 PF13080.1 EEB08738.1 - 0.16 11.5 3.0 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) DUF1805 PF08827.6 EEB08738.1 - 0.2 11.4 0.0 0.58 9.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) WD40 PF00400.27 EEB08739.1 - 1.4e-43 145.2 19.0 5.7e-10 38.6 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat AMP-binding PF00501.23 EEB08740.1 - 3.4e-82 276.0 0.0 1e-81 274.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Rhomboid PF01694.17 EEB08741.1 - 5.5e-16 58.8 8.9 2.8e-12 46.8 1.2 2.4 2 0 0 2 2 2 2 Rhomboid family zf-H2C2_2 PF13465.1 EEB08742.1 - 3.9e-07 30.0 13.0 1.1e-05 25.4 1.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEB08742.1 - 5.9e-07 29.4 15.0 0.00081 19.5 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB08742.1 - 8e-06 25.8 14.6 0.0013 18.8 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2225 PF09986.4 EEB08742.1 - 0.077 12.4 1.4 0.13 11.6 1.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EEB08742.1 - 0.16 11.9 4.2 8 6.5 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEB08742.1 - 0.2 11.8 4.1 0.35 11.0 1.5 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PTS_2-RNA PF01885.11 EEB08743.1 - 5.8e-57 192.0 0.0 9e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Yae1_N PF09811.4 EEB08743.1 - 0.0002 20.8 3.3 0.00041 19.8 2.3 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SHMT PF00464.14 EEB08744.2 - 4.2e-205 680.6 0.0 5.1e-205 680.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 EEB08744.2 - 0.15 11.0 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ras PF00071.17 EEB08745.1 - 1.7e-63 212.8 0.8 2.1e-63 212.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB08745.1 - 2.6e-20 73.1 0.1 4.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB08745.1 - 1.5e-13 50.3 0.2 2.2e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEB08745.1 - 2.7e-06 27.3 0.1 3.4e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 EEB08745.1 - 5e-05 22.5 0.2 6.1e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 EEB08745.1 - 6.6e-05 22.4 0.2 0.00013 21.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEB08745.1 - 0.00028 20.0 0.2 0.00046 19.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EEB08745.1 - 0.0004 20.5 0.1 0.0011 19.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEB08745.1 - 0.0011 18.1 0.0 0.0033 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EEB08745.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEB08745.1 - 0.019 15.2 0.3 0.031 14.5 0.2 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EEB08745.1 - 0.036 13.2 0.0 0.054 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EEB08745.1 - 0.057 12.9 1.3 0.11 12.0 0.0 2.2 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EEB08745.1 - 0.067 12.9 0.0 0.19 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3533 PF12051.3 EEB08745.1 - 0.07 11.8 0.1 0.081 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FeoB_N PF02421.13 EEB08745.1 - 0.083 12.1 0.2 0.85 8.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EEB08745.1 - 0.1 12.5 0.8 0.16 11.8 0.5 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEB08745.1 - 0.15 11.9 0.3 0.46 10.4 0.2 2.0 1 1 1 2 2 2 0 AAA ATPase domain Chromo PF00385.19 EEB08746.1 - 9.1e-13 47.6 2.4 2.2e-12 46.4 1.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_6 PF14259.1 EEB08746.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB08746.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08746.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EEB08746.1 - 0.95 7.8 79.1 0.059 11.8 30.1 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Fungal_trans PF04082.13 EEB08747.1 - 8.2e-26 90.4 0.1 1.5e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB08747.1 - 1.8e-09 37.3 13.1 1.8e-09 37.3 9.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L15e PF00827.12 EEB08748.1 - 1.4e-88 295.4 8.9 1.7e-88 295.1 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Sdh_cyt PF01127.17 EEB08749.1 - 3.1e-25 88.3 4.3 5e-25 87.6 3.0 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sin_N PF04801.8 EEB08750.1 - 2e-29 102.7 0.0 2.3e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Ribosomal_L24e PF01246.15 EEB08751.1 - 7.9e-30 102.5 0.3 7.9e-30 102.5 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e SEN1_N PF12726.2 EEB08752.1 - 6.4e-144 480.7 33.7 5.6e-143 477.6 23.3 2.0 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EEB08752.1 - 9.8e-72 241.3 0.4 9.8e-72 241.3 0.3 2.3 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EEB08752.1 - 1.9e-60 203.6 0.0 4.9e-60 202.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB08752.1 - 1.1e-11 44.3 0.1 6.7e-11 41.7 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEB08752.1 - 1.2e-06 28.2 0.1 0.00018 21.1 0.0 2.6 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EEB08752.1 - 3.9e-05 23.2 0.3 0.56 9.6 0.0 4.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EEB08752.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1014 PF06244.7 EEB08753.1 - 4.8e-29 101.0 21.3 1.1e-28 99.8 14.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) ATP11 PF06644.6 EEB08753.1 - 1.4 8.3 19.2 0.12 11.8 9.6 1.7 1 1 1 2 2 2 0 ATP11 protein Mt_ATP-synt_D PF05873.7 EEB08754.1 - 3.8e-10 39.6 3.0 4.4e-10 39.4 2.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Tmemb_cc2 PF10267.4 EEB08754.1 - 0.0036 15.9 0.2 0.0047 15.5 0.1 1.3 1 1 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein KaiC PF06745.8 EEB08754.1 - 0.051 12.6 0.4 0.065 12.3 0.3 1.2 1 0 0 1 1 1 0 KaiC AHS1 PF02682.11 EEB08754.1 - 0.12 11.8 0.6 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 DUF1664 PF07889.7 EEB08754.1 - 0.5 10.1 4.1 0.8 9.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rotamase_2 PF13145.1 EEB08754.1 - 3.1 8.4 6.4 1.3 9.6 1.6 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Rad21_Rec8_N PF04825.8 EEB08755.1 - 7.4e-28 96.7 0.1 1.7e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEB08755.1 - 1.1e-06 27.7 0.8 2.9e-06 26.3 0.0 2.2 3 0 0 3 3 3 1 Conserved region of Rad21 / Rec8 like protein AAA PF00004.24 EEB08756.1 - 3.2e-16 59.7 0.0 1.1e-15 58.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 EEB08756.1 - 3.3e-09 36.5 0.1 1.3e-08 34.6 0.1 2.1 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 EEB08756.1 - 2.2e-08 34.3 0.1 1.2e-07 31.9 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB08756.1 - 6.3e-08 32.8 0.0 3.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEB08756.1 - 0.00013 21.0 0.0 0.076 11.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EEB08756.1 - 0.00088 18.9 0.0 0.029 14.0 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 EEB08756.1 - 0.0013 18.5 0.0 0.0055 16.4 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EEB08756.1 - 0.002 17.8 0.0 0.0065 16.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 EEB08756.1 - 0.006 16.1 0.1 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mt_ATP-synt_D PF05873.7 EEB08756.1 - 0.023 14.3 0.1 7.5 6.1 0.0 2.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) LAMTOR PF15454.1 EEB08757.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Cyt-b5 PF00173.23 EEB08758.2 - 7.9e-25 86.4 0.1 1e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1682 PF07946.9 EEB08759.1 - 8.1e-73 245.0 0.0 9.5e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Red1 PF07964.6 EEB08759.1 - 7.5e-06 24.4 1.4 2.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Rec10 / Red1 DUF945 PF06097.6 EEB08759.1 - 0.037 12.8 2.9 0.053 12.2 2.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) V-ATPase_G PF03179.10 EEB08759.1 - 0.098 12.9 7.7 0.24 11.7 5.3 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mt_ATP-synt_B PF05405.9 EEB08759.1 - 0.45 9.9 4.4 9.6 5.6 0.7 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CK_II_beta PF01214.13 EEB08760.2 - 6.5e-73 244.1 0.0 7.9e-73 243.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p62 PF05502.8 EEB08760.2 - 0.095 11.4 0.8 0.13 10.9 0.5 1.1 1 0 0 1 1 1 0 Dynactin p62 family ATP_bind_3 PF01171.15 EEB08761.1 - 1.3e-19 70.3 0.0 2.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EEB08761.1 - 0.0006 19.3 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase DUF2392 PF10288.4 EEB08761.1 - 0.0021 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EEB08761.1 - 0.0027 16.3 0.0 0.004 15.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 EEB08761.1 - 0.0049 16.2 0.5 0.0049 16.2 0.4 3.5 5 0 0 5 5 5 1 RecR protein DUF3970 PF13113.1 EEB08761.1 - 0.043 13.5 0.5 0.094 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) DUF4428 PF14471.1 EEB08761.1 - 0.081 12.6 3.8 0.095 12.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) PHF5 PF03660.9 EEB08761.1 - 0.19 11.7 6.6 2 8.4 0.2 2.6 3 0 0 3 3 2 0 PHF5-like protein DZR PF12773.2 EEB08761.1 - 0.42 10.4 12.2 0.23 11.2 0.6 3.2 3 0 0 3 3 3 0 Double zinc ribbon HIPIP PF01355.12 EEB08761.1 - 1.3 9.1 5.1 3.1 7.9 0.1 3.1 3 0 0 3 3 3 0 High potential iron-sulfur protein DUF2616 PF11077.3 EEB08761.1 - 3.3 7.1 7.7 0.43 10.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) COPIIcoated_ERV PF07970.7 EEB08762.1 - 1.9e-30 106.1 0.0 3.3e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEB08762.1 - 4e-21 74.8 2.1 6.7e-21 74.0 0.5 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sigma_reg_N PF13800.1 EEB08762.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Transketolase_N PF00456.16 EEB08763.1 - 1.8e-143 477.3 0.0 2.4e-143 476.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EEB08763.1 - 4.3e-48 163.1 0.0 1e-47 161.9 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEB08763.1 - 8.7e-14 51.5 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EEB08763.1 - 5.5e-05 22.0 0.0 8.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEB08763.1 - 0.026 13.4 0.0 0.083 11.8 0.0 1.9 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Acyltransferase PF01553.16 EEB08764.1 - 1.3e-26 92.5 0.1 3e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Mob1_phocein PF03637.12 EEB08765.1 - 8.6e-77 256.7 1.2 1e-76 256.5 0.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family RRM_1 PF00076.17 EEB08766.1 - 2e-19 68.9 0.0 2.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08766.1 - 6.7e-11 42.0 0.0 9.6e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08766.1 - 1.9e-10 40.4 0.0 2.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08766.1 - 0.00044 19.9 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EEB08766.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Limkain-b1 PF11608.3 EEB08766.1 - 0.031 14.0 0.1 0.072 12.8 0.1 1.7 1 1 0 1 1 1 0 Limkain b1 UCR_14kD PF02271.11 EEB08766.1 - 0.05 13.3 0.1 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Spt5-NGN PF03439.8 EEB08766.1 - 0.12 12.1 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Sec5 PF15469.1 EEB08767.2 - 9.7e-26 90.5 0.4 9.7e-26 90.5 0.3 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Imm26 PF15572.1 EEB08767.2 - 0.013 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 26 RRM_6 PF14259.1 EEB08768.1 - 4.5e-11 42.5 0.0 9.9e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB08768.1 - 7e-08 31.9 0.0 5.8e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08768.1 - 1.4e-06 27.9 0.0 0.0084 15.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EEB08768.1 - 2.8e-05 23.8 0.0 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EEB08768.1 - 0.0024 17.5 3.1 0.0044 16.6 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EEB08768.1 - 0.017 14.9 2.7 0.11 12.3 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Bul1_C PF04426.7 EEB08768.1 - 0.029 13.5 1.2 0.05 12.7 0.8 1.3 1 0 0 1 1 1 0 Bul1 C terminus DUF1330 PF07045.6 EEB08768.1 - 0.067 13.0 4.0 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) DUF3287 PF11690.3 EEB08768.1 - 0.081 12.9 2.0 0.13 12.3 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Spo7 PF03907.8 EEB08769.1 - 2.4e-42 144.9 9.1 6.1e-34 117.4 4.2 2.0 1 1 1 2 2 2 2 Spo7-like protein Histone PF00125.19 EEB08770.1 - 3.2e-23 81.6 0.3 4.4e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB08770.1 - 1.9e-06 27.8 0.1 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEB08770.1 - 6.1e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RNA_pol_Rpb2_1 PF04563.10 EEB08770.1 - 0.96 8.3 3.2 6.2 5.6 0.1 2.0 1 1 1 2 2 2 0 RNA polymerase beta subunit Histone PF00125.19 EEB08771.1 - 8.2e-26 89.9 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB08771.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HIT PF01230.18 EEB08771.1 - 0.072 13.6 0.0 0.1 13.1 0.0 1.3 1 1 0 1 1 1 0 HIT domain FA_desaturase PF00487.19 EEB08772.1 - 1.2e-19 70.7 18.5 6.5e-19 68.3 11.7 2.1 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEB08772.1 - 9.1e-10 38.1 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CRC_subunit PF08624.5 EEB08773.1 - 3.9e-57 192.0 0.0 5.9e-57 191.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.24 EEB08774.2 - 9.2e-11 41.2 8.1 1.6e-10 40.5 5.6 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EEB08774.2 - 0.01 15.5 3.9 0.01 15.5 2.7 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EEB08774.2 - 0.012 14.8 5.9 0.039 13.2 4.1 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zinc-ribbons_6 PF07191.7 EEB08774.2 - 0.26 11.1 4.0 0.5 10.1 2.8 1.4 1 0 0 1 1 1 0 zinc-ribbons PHD_2 PF13831.1 EEB08774.2 - 0.3 10.4 11.1 0.074 12.3 4.2 2.5 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 EEB08774.2 - 0.69 9.6 10.9 0.088 12.5 3.5 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EEB08774.2 - 1.4 8.7 5.3 4.3 7.2 3.8 1.7 1 1 1 2 2 2 0 Double zinc ribbon DUF4206 PF13901.1 EEB08774.2 - 2.2 7.8 6.9 4.6 6.7 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) OrfB_Zn_ribbon PF07282.6 EEB08774.2 - 3 7.5 5.6 1 9.0 1.3 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NAD_kinase PF01513.16 EEB08775.1 - 9.7e-53 178.7 0.0 1.2e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EEB08775.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_tran_28_C PF04101.11 EEB08775.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Proteasome PF00227.21 EEB08777.1 - 9.8e-57 191.3 0.1 1.3e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB08777.1 - 2.2e-14 52.4 0.0 3.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.22 EEB08778.2 - 6.2e-36 123.7 0.0 1.5e-17 64.1 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEB08778.2 - 9.9e-15 55.2 1.0 1.1e-05 25.5 0.0 3.8 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EEB08778.2 - 1.4e-05 24.4 0.1 0.017 14.6 0.0 2.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 EEB08778.2 - 0.00013 21.2 0.4 0.89 8.7 0.1 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EEB08778.2 - 0.00013 21.7 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EEB08778.2 - 0.00019 21.8 0.0 0.64 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEB08778.2 - 0.00058 20.3 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EEB08778.2 - 0.001 18.2 0.0 14 4.6 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain NACHT PF05729.7 EEB08778.2 - 0.0014 18.3 0.4 0.3 10.7 0.0 3.4 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EEB08778.2 - 0.0018 18.2 0.1 1.3 9.0 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEB08778.2 - 0.0037 16.7 0.0 0.9 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EEB08778.2 - 0.0056 16.8 0.4 5.9 7.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEB08778.2 - 0.0082 16.0 0.0 0.24 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EEB08778.2 - 0.015 14.9 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EEB08778.2 - 0.026 13.9 0.3 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EEB08778.2 - 0.059 12.6 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_10 PF12846.2 EEB08778.2 - 0.084 12.2 3.6 3.4 6.9 0.1 3.0 3 1 0 3 3 3 0 AAA-like domain AAA_17 PF13207.1 EEB08778.2 - 0.12 13.2 0.0 17 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Methyltransf_26 PF13659.1 EEB08779.1 - 1.8e-10 40.9 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB08779.1 - 2.2e-06 27.1 0.0 3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Saccharop_dh PF03435.13 EEB08779.1 - 0.091 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_4 PF02390.12 EEB08779.1 - 0.13 11.3 0.0 2.4 7.1 0.0 2.4 3 0 0 3 3 3 0 Putative methyltransferase ThiF PF00899.16 EEB08780.1 - 6.7e-10 38.9 0.1 2.3e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EEB08780.1 - 0.0078 15.7 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 MoeZ/MoeB domain MatE PF01554.13 EEB08781.1 - 4.1e-53 179.3 35.3 2.4e-31 108.5 6.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EEB08781.1 - 0.00014 21.6 12.7 0.00014 21.6 8.8 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF4477 PF14780.1 EEB08782.1 - 8.5e-06 25.2 1.0 0.0049 16.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) Adeno_E1B_19K PF01691.11 EEB08782.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Herpes_DNAp_acc PF04929.7 EEB08782.1 - 1.1 8.1 6.5 1.5 7.7 4.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PBP1_TM PF14812.1 EEB08782.1 - 2.9 8.2 7.7 0.35 11.2 1.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TSGP1 PF07771.6 EEB08782.1 - 3.7 7.4 5.8 6.4 6.6 4.0 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Gly_transf_sug PF04488.10 EEB08783.1 - 1e-17 64.3 0.2 6.3e-17 61.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EEB08783.1 - 0.0044 16.2 0.2 0.0056 15.8 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein LSM PF01423.17 EEB08784.1 - 2.6e-20 71.7 0.1 2.9e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEB08784.1 - 7.4e-06 25.8 0.0 8.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_11 PF13414.1 EEB08785.1 - 1.2e-11 44.0 11.8 6.7e-08 32.0 1.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEB08785.1 - 1.4e-08 34.0 6.4 0.0026 17.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEB08785.1 - 1.7e-06 27.4 9.0 0.22 11.5 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEB08785.1 - 0.00097 19.0 6.2 0.028 14.3 1.8 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEB08785.1 - 0.076 13.3 3.4 0.094 13.0 1.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEB08785.1 - 0.2 12.3 5.3 0.8 10.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEB08785.1 - 0.33 11.6 8.1 2 9.1 3.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_I_A49 PF06870.7 EEB08786.1 - 2.3e-102 342.4 0.8 2.8e-102 342.1 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SSB PF00436.20 EEB08787.1 - 1.5e-10 40.8 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Aldo_ket_red PF00248.16 EEB08788.1 - 1.2e-53 181.7 0.0 1.5e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HEAT PF02985.17 EEB08789.1 - 2.1e-23 80.2 7.0 0.0035 17.2 0.0 10.1 11 0 0 11 11 11 6 HEAT repeat HEAT_EZ PF13513.1 EEB08789.1 - 2.2e-20 72.5 5.9 7e-11 42.2 0.0 9.4 10 1 2 12 12 12 2 HEAT-like repeat HEAT_2 PF13646.1 EEB08789.1 - 5.8e-20 71.3 0.1 0.00016 21.8 0.0 7.3 5 2 3 8 8 8 5 HEAT repeats Cnd1 PF12717.2 EEB08789.1 - 2.4e-08 34.0 0.4 0.85 9.4 0.0 5.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEB08789.1 - 5e-08 33.2 0.0 0.4 11.0 0.0 5.2 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EEB08789.1 - 7e-08 32.0 3.4 2.1 8.2 0.0 6.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EEB08789.1 - 3.6e-06 25.5 0.3 0.0087 14.4 0.0 3.2 2 1 0 2 2 2 2 Adaptin N terminal region IBN_N PF03810.14 EEB08789.1 - 4.9e-05 23.1 0.1 0.00023 21.0 0.0 2.3 1 1 0 1 1 1 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EEB08789.1 - 0.00092 18.6 0.1 22 4.3 0.0 4.8 4 1 0 4 4 4 0 CLASP N terminal ParcG PF10274.4 EEB08789.1 - 0.029 14.2 0.1 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein FA_FANCE PF11510.3 EEB08789.1 - 0.047 12.8 0.6 3.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Fanconi Anaemia group E protein FANCE MFS_2 PF13347.1 EEB08790.1 - 4.9e-11 41.6 16.3 4.9e-11 41.6 11.3 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Aminotran_1_2 PF00155.16 EEB08791.1 - 1.2e-70 238.2 0.0 1.8e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEB08791.1 - 7.1e-05 21.7 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEB08791.1 - 0.00034 19.0 0.0 0.00062 18.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Preseq_ALAS PF09029.5 EEB08791.1 - 0.0023 17.9 0.1 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DHHA1 PF02272.14 EEB08791.1 - 0.031 13.9 0.2 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 DHHA1 domain TPR_8 PF13181.1 EEB08791.1 - 0.21 11.4 1.9 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sdh_cyt PF01127.17 EEB08792.2 - 0.064 13.0 0.6 0.079 12.7 0.4 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF202 PF02656.10 EEB08792.2 - 0.16 12.2 0.3 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Vps54 PF07928.7 EEB08793.1 - 4.3e-27 94.8 0.2 2.3e-26 92.5 0.0 2.4 2 0 0 2 2 2 1 Vps54-like protein DUF2063 PF09836.4 EEB08793.1 - 0.036 14.0 0.0 0.6 10.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) DHHA2 PF02833.9 EEB08794.1 - 4.5e-20 72.1 0.1 7.8e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EEB08794.1 - 1.8e-13 50.3 0.7 4.2e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 DHH family Mso1_Sec1_bdg PF14475.1 EEB08794.1 - 0.0043 16.4 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Sec1-binding region of Mso1 TSC22 PF01166.13 EEB08794.1 - 0.1 12.5 0.1 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family WW PF00397.21 EEB08797.1 - 7.9e-05 22.4 1.7 0.00016 21.4 1.2 1.5 1 0 0 1 1 1 1 WW domain Pkinase PF00069.20 EEB08798.2 - 7e-78 261.3 0.0 9.2e-78 260.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08798.2 - 3.2e-34 118.1 0.0 4.5e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08798.2 - 0.005 15.8 0.0 0.036 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB08798.2 - 0.017 14.8 0.0 2.6 7.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family zinc_ribbon_6 PF14599.1 EEB08799.1 - 2.4e-23 81.7 3.2 2.4e-23 81.7 2.2 4.2 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EEB08799.1 - 1.7e-12 47.3 28.2 1.7e-12 47.3 19.6 4.5 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EEB08799.1 - 1.7e-08 34.1 6.6 1.7e-08 34.1 4.6 5.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB08799.1 - 8e-07 28.9 6.6 8e-07 28.9 4.6 6.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB08799.1 - 0.00017 21.2 6.8 0.00017 21.2 4.7 6.9 4 3 1 5 5 5 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EEB08799.1 - 0.00056 19.5 0.7 0.00056 19.5 0.5 6.6 4 3 2 6 6 6 1 Prokaryotic RING finger family 1 DUF1542 PF07564.6 EEB08799.1 - 0.0058 16.6 0.2 0.0058 16.6 0.1 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) LMBR1 PF04791.11 EEB08799.1 - 0.17 10.4 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Big_1 PF02369.11 EEB08800.1 - 0.0048 16.7 1.0 0.0048 16.7 0.7 2.3 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) SKG6 PF08693.5 EEB08800.1 - 0.0048 16.1 3.5 0.0048 16.1 2.4 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EEB08800.1 - 0.017 14.3 0.1 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4448 PF14610.1 EEB08800.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) HECT PF00632.20 EEB08801.1 - 4.1e-99 331.7 0.2 5.8e-99 331.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEB08801.1 - 4.6e-34 115.8 21.4 1.7e-11 43.7 3.7 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EEB08801.1 - 1e-17 63.7 0.1 2.6e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain ubiquitin PF00240.18 EEB08802.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEB08802.1 - 8.5e-31 105.3 11.3 1.3e-30 104.6 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEB08802.1 - 4.1e-20 71.2 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEB08802.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEB08802.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEB08802.1 - 0.007 16.2 0.1 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEB08802.1 - 0.011 15.9 0.1 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEB08802.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EEB08802.1 - 0.19 11.5 1.9 0.87 9.4 1.3 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Acyl_transf_1 PF00698.16 EEB08803.1 - 8e-20 71.4 0.0 1.2e-18 67.4 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain DUF1864 PF08933.6 EEB08803.1 - 0.1 11.1 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Ecl1 PF12855.2 EEB08804.1 - 3.4e-05 23.0 7.6 3.4e-05 23.0 5.2 1.5 1 1 0 1 1 1 1 Life-span regulatory factor zf-NF-X1 PF01422.12 EEB08804.1 - 0.0065 16.4 3.2 0.0065 16.4 2.2 1.8 3 0 0 3 3 3 1 NF-X1 type zinc finger Thg1 PF04446.7 EEB08804.1 - 0.031 13.8 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 tRNAHis guanylyltransferase DUF2116 PF09889.4 EEB08804.1 - 0.071 12.9 1.1 0.17 11.6 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ZZ PF00569.12 EEB08806.2 - 5.2e-14 51.5 40.8 1.3e-06 27.7 4.9 3.8 3 1 0 3 3 3 3 Zinc finger, ZZ type C1_3 PF07649.7 EEB08806.2 - 0.00014 21.7 51.4 0.00018 21.4 6.6 4.1 4 0 0 4 4 4 3 C1-like domain NUDIX PF00293.23 EEB08807.1 - 3e-15 56.0 0.5 8.3e-15 54.6 0.0 1.9 1 1 1 2 2 2 1 NUDIX domain Med15_fungi PF05397.7 EEB08810.2 - 3.7e-24 84.9 0.0 3.7e-24 84.9 0.0 5.2 5 2 2 7 7 7 1 Mediator complex subunit 15 SNF2_N PF00176.18 EEB08811.1 - 2.6e-57 193.9 0.2 4.3e-57 193.1 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB08811.1 - 6e-17 61.2 0.1 2.4e-15 56.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEB08811.1 - 2e-13 49.7 3.7 2e-13 49.7 2.5 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EEB08811.1 - 0.00012 21.7 1.1 0.047 13.3 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EEB08811.1 - 0.00018 21.1 9.1 0.00018 21.1 6.3 2.7 2 0 0 2 2 2 1 PHD-finger zf-U1 PF06220.7 EEB08812.1 - 1.6e-12 46.7 0.5 4.1e-12 45.4 0.4 1.7 1 0 0 1 1 1 1 U1 zinc finger PAT1 PF09770.4 EEB08812.1 - 0.99 7.5 8.5 1.1 7.3 5.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCHC PF00098.18 EEB08813.1 - 2.8e-10 39.6 30.7 8e-05 22.3 3.3 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.1 EEB08813.1 - 0.035 13.7 0.5 0.035 13.7 0.4 5.3 4 1 1 5 5 5 0 Zinc knuckle TPP_enzyme_N PF02776.13 EEB08814.1 - 9.7e-59 197.7 0.5 3.5e-58 195.8 0.1 2.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEB08814.1 - 1.7e-49 167.2 0.1 2.5e-48 163.5 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEB08814.1 - 1.3e-39 135.0 0.0 4.1e-39 133.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Nucleoporin_N PF08801.6 EEB08815.1 - 6.7e-18 64.6 0.6 6.7e-18 64.6 0.4 1.8 2 0 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.20 EEB08816.1 - 6e-33 114.0 0.0 8.1e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08816.1 - 3e-10 39.6 0.0 4.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB08816.1 - 6.5e-05 22.7 0.0 0.0099 15.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Shugoshin_N PF07558.6 EEB08817.1 - 7.6e-05 22.3 2.2 7.6e-05 22.3 1.5 1.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Leu_zip PF15294.1 EEB08817.1 - 0.0042 16.2 4.4 0.0066 15.5 3.0 1.3 1 0 0 1 1 1 1 Leucine zipper NAD_binding_4 PF07993.7 EEB08817.1 - 0.0047 15.8 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein DUF904 PF06005.7 EEB08817.1 - 0.018 15.3 1.8 0.018 15.3 1.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Jnk-SapK_ap_N PF09744.4 EEB08817.1 - 0.026 14.5 1.5 0.048 13.6 1.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sec20 PF03908.8 EEB08817.1 - 0.11 12.2 2.5 0.2 11.3 1.7 1.4 1 0 0 1 1 1 0 Sec20 Baculo_PEP_C PF04513.7 EEB08817.1 - 0.12 12.2 2.6 0.19 11.5 1.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EEB08817.1 - 0.18 12.1 3.7 2.5 8.4 2.0 2.4 1 1 1 2 2 2 0 Snapin/Pallidin TBPIP PF07106.8 EEB08817.1 - 0.25 10.8 3.7 0.52 9.8 2.6 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EEB08817.1 - 0.39 11.0 5.3 0.13 12.6 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EEB08817.1 - 0.53 10.1 7.7 1.9 8.3 1.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEB08817.1 - 0.99 8.9 6.8 0.26 10.8 2.4 1.6 2 0 0 2 2 2 0 IncA protein Striatin PF08232.7 EEB08817.1 - 2.4 8.4 12.8 1.7 8.9 0.4 3.4 2 2 1 3 3 3 0 Striatin family PITH PF06201.8 EEB08818.1 - 3.4e-39 134.0 0.0 4.2e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ima1_N PF09779.4 EEB08819.1 - 0.12 12.9 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain LURAP PF14854.1 EEB08819.1 - 2.7 7.7 5.9 1.1 8.9 1.2 2.2 1 1 1 2 2 2 0 Leucine rich adaptor protein Evr1_Alr PF04777.8 EEB08820.1 - 4.1e-26 90.7 0.0 5.9e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family CWC25 PF12542.3 EEB08821.1 - 5.3e-21 74.8 7.2 5.3e-21 74.8 5.0 3.7 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EEB08821.1 - 4.6e-15 55.3 13.2 4.6e-15 55.3 9.1 5.3 4 0 0 4 4 4 2 N-terminal domain of CBF1 interacting co-repressor CIR VRR_NUC PF08774.6 EEB08822.1 - 1.3e-18 66.8 0.1 3.9e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 VRR-NUC domain RRM_1 PF00076.17 EEB08823.2 - 1.8e-23 81.9 0.1 2.7e-15 55.7 0.0 4.2 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08823.2 - 3.8e-17 62.0 0.0 3.1e-06 27.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08823.2 - 4.3e-14 52.0 0.0 0.00013 21.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX16 PF14138.1 EEB08823.2 - 8.3 6.6 7.6 12 6.2 3.7 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 eIF-1a PF01176.14 EEB08824.1 - 3.1e-20 71.3 0.1 5e-20 70.6 0.0 1.4 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 Amino_oxidase PF01593.19 EEB08825.2 - 1.8e-55 188.8 0.0 3.3e-54 184.6 0.0 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EEB08825.2 - 1.5e-11 44.2 0.0 3.4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_9 PF13454.1 EEB08825.2 - 2e-06 27.6 0.1 0.039 13.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEB08825.2 - 2.3e-06 27.5 0.0 5.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EEB08825.2 - 2.9e-06 27.4 0.4 1.1e-05 25.5 0.3 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_3 PF13738.1 EEB08825.2 - 9.1e-05 22.6 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.5 EEB08825.2 - 0.0059 16.9 1.8 0.01 16.2 0.5 2.0 1 1 1 2 2 2 1 HMG-box domain DAO PF01266.19 EEB08825.2 - 0.0067 15.3 0.0 0.076 11.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEB08825.2 - 0.017 14.9 0.0 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.17 EEB08826.1 - 7.8e-06 25.9 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain NgoMIV_restric PF09015.5 EEB08826.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme FAD_binding_3 PF01494.14 EEB08828.1 - 1.8e-22 79.8 0.0 3.3e-21 75.7 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEB08828.1 - 1.1e-06 27.8 0.5 0.0041 16.0 0.1 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein SE PF08491.5 EEB08828.1 - 0.00038 19.3 0.0 0.00054 18.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EEB08828.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEB08828.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEB08828.1 - 0.0022 16.9 0.1 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEB08828.1 - 0.0048 16.9 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB08828.1 - 0.0053 16.7 0.2 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEB08828.1 - 0.011 14.5 0.0 0.044 12.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EEB08828.1 - 0.042 12.9 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EEB08828.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EEB08828.1 - 0.16 10.4 0.7 0.33 9.3 0.5 1.6 1 1 0 1 1 1 0 HI0933-like protein Myosin_head PF00063.16 EEB08829.1 - 1.4e-229 763.7 5.9 2.3e-229 763.0 4.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EEB08829.1 - 7.1e-46 156.0 0.2 1.2e-45 155.3 0.1 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EEB08829.1 - 1.9e-16 59.1 0.1 1.2e-15 56.6 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEB08829.1 - 1.8e-13 49.8 0.0 9.9e-13 47.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEB08829.1 - 5.5e-10 38.5 0.0 2.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EEB08829.1 - 0.0011 19.0 0.1 0.012 15.7 0.0 2.6 2 1 1 3 3 3 1 Bacterial SH3 domain DUF552 PF04472.7 EEB08829.1 - 0.0024 17.7 0.7 0.8 9.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF552) AAA_22 PF13401.1 EEB08829.1 - 0.0025 17.9 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB08829.1 - 0.0061 17.3 0.0 0.028 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEB08829.1 - 0.014 14.4 0.0 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.7 EEB08829.1 - 0.054 12.7 0.2 5.9 6.1 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 EEB08829.1 - 0.075 13.3 0.1 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEB08829.1 - 0.079 12.9 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.22 EEB08829.1 - 5.3 6.9 8.5 3 7.7 2.5 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif Adaptin_N PF01602.15 EEB08830.1 - 6.6e-90 301.9 13.1 1e-89 301.3 9.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EEB08830.1 - 3.2e-58 195.0 0.1 9.9e-58 193.4 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EEB08830.1 - 5.2e-56 188.2 0.6 1.2e-55 187.0 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EEB08830.1 - 9.3e-13 48.2 6.4 3.1e-05 24.1 0.0 5.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EEB08830.1 - 2.1e-05 24.2 0.4 0.05 13.6 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.18 EEB08830.1 - 0.00061 19.5 1.3 5 7.0 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EEB08830.1 - 0.00066 20.0 3.2 3.5 8.2 0.2 4.7 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 EEB08830.1 - 0.0015 18.4 6.4 0.012 15.4 0.0 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EEB08830.1 - 0.0042 17.0 9.8 3.6 7.4 0.5 4.2 3 1 1 4 4 4 3 Parkin co-regulated protein Tubulin PF00091.20 EEB08831.1 - 4.9e-72 242.2 0.0 7.7e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEB08831.1 - 1.2e-46 157.8 0.2 2.3e-46 156.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEB08831.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEB08831.1 - 0.0027 17.2 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GN3L_Grn1 PF08701.6 EEB08832.1 - 6.4e-25 86.8 11.1 2e-24 85.2 7.7 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EEB08832.1 - 1.2e-21 76.8 0.2 2.3e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEB08832.1 - 7.3e-09 35.6 5.4 0.00029 20.7 0.1 3.7 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EEB08832.1 - 1.2e-06 28.0 0.0 0.0031 16.9 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEB08832.1 - 1.7e-06 27.3 0.7 6.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EEB08832.1 - 9.4e-05 22.8 0.1 0.2 12.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EEB08832.1 - 0.0015 17.7 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 EEB08832.1 - 0.033 12.9 0.8 0.19 10.4 0.0 2.5 3 0 0 3 3 3 0 ArgK protein IIGP PF05049.8 EEB08832.1 - 0.057 12.2 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 EEB08832.1 - 0.098 11.7 0.1 0.37 9.8 0.1 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Arf PF00025.16 EEB08832.1 - 0.16 11.1 1.2 1.3 8.2 0.3 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 EEB08832.1 - 0.42 10.5 2.9 0.99 9.3 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain CRC_subunit PF08624.5 EEB08833.1 - 4.7e-42 143.1 0.0 8.5e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Asp-B-Hydro_N PF05279.6 EEB08833.1 - 9.5 5.9 19.8 13 5.5 13.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RNB PF00773.14 EEB08834.1 - 8.1e-95 317.8 0.1 1.1e-94 317.3 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EEB08834.1 - 4.9e-13 49.3 0.1 1.4e-12 47.8 0.1 1.9 1 0 0 1 1 1 1 PIN domain 4HBT PF03061.17 EEB08835.1 - 0.00099 19.1 0.0 0.0018 18.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DUF359 PF04019.7 EEB08835.1 - 0.036 13.4 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) Cyto_heme_lyase PF01265.12 EEB08836.1 - 1.9e-50 171.8 0.7 1.9e-50 171.8 0.5 1.4 2 0 0 2 2 2 1 Cytochrome c/c1 heme lyase HMG_box PF00505.14 EEB08837.2 - 8.3e-14 51.6 0.2 1.4e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EEB08837.2 - 0.00046 19.5 0.2 0.00084 18.7 0.1 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 EEB08837.2 - 0.098 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Sec7 PF01369.15 EEB08838.1 - 2.9e-16 59.7 2.3 8.9e-16 58.1 1.6 1.8 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEB08838.1 - 0.00062 19.9 0.0 0.004 17.2 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain RPN7 PF10602.4 EEB08839.1 - 1.7e-40 138.2 2.6 3.6e-40 137.2 1.8 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEB08839.1 - 2.5e-11 43.8 0.3 1.7e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 PCI domain DUF2250 PF10007.4 EEB08839.1 - 1.6e-05 24.6 0.0 0.00016 21.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EEB08839.1 - 0.038 13.6 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TPR_14 PF13428.1 EEB08839.1 - 0.047 14.3 1.4 0.15 12.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIS_M PF07500.9 EEB08839.1 - 0.061 13.3 0.6 0.15 12.1 0.2 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain HTH_27 PF13463.1 EEB08839.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain TPR_2 PF07719.12 EEB08839.1 - 0.33 10.9 6.9 1.7 8.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEB08839.1 - 0.72 9.5 5.2 3.4 7.4 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Prefoldin PF02996.12 EEB08840.1 - 3.2e-26 91.3 0.9 4.8e-26 90.7 0.2 1.6 1 1 1 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.15 EEB08840.1 - 0.00064 19.4 4.2 0.017 14.8 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF1192 PF06698.6 EEB08840.1 - 0.00079 19.1 1.3 0.005 16.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) MCPsignal PF00015.16 EEB08840.1 - 0.0054 16.2 1.5 0.0065 16.0 0.1 1.8 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE PF05008.10 EEB08840.1 - 0.018 15.1 1.5 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus LURAP PF14854.1 EEB08840.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein Reo_sigmaC PF04582.7 EEB08840.1 - 0.068 12.3 0.4 0.11 11.6 0.3 1.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2730 PF10805.3 EEB08840.1 - 0.12 12.1 0.3 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) SlyX PF04102.7 EEB08840.1 - 0.13 12.6 0.8 0.85 10.0 0.1 2.1 2 0 0 2 2 2 0 SlyX Sec2p PF06428.6 EEB08840.1 - 0.27 11.0 2.5 2 8.3 0.0 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p RabGAP-TBC PF00566.13 EEB08841.1 - 9e-52 175.6 0.4 2e-51 174.4 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EEB08841.1 - 2.3e-05 24.4 0.6 0.0016 18.5 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEB08841.1 - 0.017 14.4 0.1 0.35 10.2 0.0 2.9 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EEB08841.1 - 0.018 14.9 0.2 1.7 8.7 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain GrpE PF01025.14 EEB08842.1 - 7.6e-50 168.6 2.1 9.4e-50 168.3 1.5 1.0 1 0 0 1 1 1 1 GrpE IncA PF04156.9 EEB08842.1 - 0.011 15.4 2.6 0.014 15.0 1.8 1.2 1 0 0 1 1 1 0 IncA protein Lge1 PF11488.3 EEB08842.1 - 0.013 15.6 4.3 0.013 15.6 3.0 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Peptidase_S49 PF01343.13 EEB08842.1 - 0.031 14.0 0.6 0.043 13.5 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 DUF3584 PF12128.3 EEB08842.1 - 0.036 11.4 3.7 0.044 11.1 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF924 PF06041.6 EEB08842.1 - 0.078 12.7 0.1 0.097 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) TBPIP PF07106.8 EEB08842.1 - 0.11 12.0 4.6 0.15 11.5 3.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4446 PF14584.1 EEB08842.1 - 0.13 12.0 3.8 1.3 8.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) OmpH PF03938.9 EEB08842.1 - 0.28 11.1 6.1 0.37 10.7 4.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.1 EEB08842.1 - 0.3 11.1 5.2 0.39 10.7 3.3 1.4 1 1 0 1 1 1 0 Syntaxin-like protein PhoU PF01895.14 EEB08842.1 - 0.34 11.3 5.4 0.32 11.4 2.6 1.7 1 1 1 2 2 2 0 PhoU domain DUF641 PF04859.7 EEB08842.1 - 0.37 10.5 4.3 0.13 12.0 0.4 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Med9 PF07544.8 EEB08842.1 - 0.43 10.3 4.1 5.6 6.7 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Bap31 PF05529.7 EEB08842.1 - 0.82 9.1 6.6 0.16 11.4 0.4 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EEB08842.1 - 1.8 7.9 10.7 0.73 9.2 4.0 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EEB08842.1 - 4 7.3 10.4 0.33 10.7 2.2 2.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EEB08842.1 - 6.9 6.2 8.7 5.9 6.4 4.9 1.7 1 1 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 EEB08842.1 - 7 7.0 9.3 4.6 7.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATP-synt_F PF01990.12 EEB08843.1 - 1.6e-29 102.0 0.4 1.9e-29 101.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Fe-S_biosyn PF01521.15 EEB08844.2 - 2e-13 50.2 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Nup160 PF11715.3 EEB08845.1 - 4.8e-46 157.0 0.1 7.5e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB08845.1 - 0.0042 15.9 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Sterol-sensing PF12349.3 EEB08846.1 - 1.1e-25 89.8 6.5 2.8e-25 88.5 4.5 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.27 EEB08846.1 - 0.096 12.6 1.4 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat dsrm PF00035.20 EEB08847.1 - 1.8e-12 47.6 0.0 4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EEB08847.1 - 5.5e-05 23.1 0.0 0.00017 21.5 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease-III-like DND1_DSRM PF14709.1 EEB08847.1 - 0.022 15.0 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_60s PF00428.14 EEB08848.1 - 2.4e-26 91.9 13.6 3e-26 91.6 9.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sybindin PF04099.7 EEB08849.1 - 8.4e-46 155.2 0.5 9.2e-46 155.0 0.4 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEB08849.1 - 7.5e-08 32.3 0.6 1.3e-07 31.5 0.4 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region CSTF2_hinge PF14327.1 EEB08850.1 - 3e-22 78.5 1.9 3e-22 78.5 1.3 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EEB08850.1 - 2.3e-21 75.2 0.0 3.6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EEB08850.1 - 8.3e-13 47.3 1.5 8.3e-13 47.3 1.0 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EEB08850.1 - 2.6e-12 46.5 0.0 6.3e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08850.1 - 6.5e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DASH_Dad4 PF08650.5 EEB08851.1 - 6.2e-30 102.9 6.4 6.7e-30 102.8 4.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Pecanex_C PF05041.10 EEB08851.1 - 0.0077 15.2 0.2 0.0077 15.2 0.2 1.1 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DASH_Dad1 PF08649.5 EEB08851.1 - 0.011 15.3 2.3 0.017 14.7 1.6 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 DASH_Dam1 PF08653.5 EEB08851.1 - 0.083 12.6 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 V-SNARE_C PF12352.3 EEB08852.1 - 2.3e-17 62.8 4.6 4.5e-17 61.8 2.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EEB08852.1 - 9.7e-16 57.7 0.9 9.7e-16 57.7 0.6 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus TroA PF01297.12 EEB08852.1 - 0.0054 16.0 1.7 0.012 14.8 0.1 2.0 2 0 0 2 2 2 1 Periplasmic solute binding protein family Prominin PF05478.6 EEB08852.1 - 0.24 8.8 3.5 2.2 5.6 2.4 2.0 1 1 0 1 1 1 0 Prominin YqjK PF13997.1 EEB08852.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.7 4 0 0 4 4 4 0 YqjK-like protein Syntaxin-6_N PF09177.6 EEB08852.1 - 2.3 8.7 4.6 4 7.9 0.3 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal EAP30 PF04157.11 EEB08853.1 - 1.2e-27 96.5 1.2 2.6e-27 95.4 0.8 1.6 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EEB08853.1 - 5.4e-20 71.0 0.1 1.3e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EEB08853.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 EEB08853.1 - 0.0078 15.2 0.5 0.0078 15.2 0.3 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.2 EEB08853.1 - 0.028 14.2 4.5 0.26 11.1 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon TFIIH_BTF_p62_N PF08567.6 EEB08853.1 - 0.03 13.9 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Cript PF10235.4 EEB08853.1 - 0.068 13.5 4.4 0.45 10.8 0.1 2.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Flavodoxin_NdrI PF07972.6 EEB08853.1 - 0.13 12.2 0.4 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like YokU PF14122.1 EEB08853.1 - 0.37 10.5 2.7 2.6 7.8 0.0 3.0 2 1 0 2 2 2 0 YokU-like protein zf-Mss51 PF13824.1 EEB08853.1 - 0.79 9.6 6.7 7.2 6.5 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Mago_nashi PF02792.9 EEB08854.2 - 2e-79 264.2 0.5 2.2e-79 264.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein adh_short PF00106.20 EEB08856.1 - 6.3e-29 101.0 0.0 9.1e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEB08856.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEB08856.1 - 3.7e-08 33.4 0.4 4.6e-08 33.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEB08856.1 - 0.0029 17.3 0.4 0.0073 16.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EEB08856.1 - 0.03 13.2 0.3 0.046 12.6 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Na_Ca_ex PF01699.19 EEB08857.1 - 7.7e-30 103.3 33.1 1e-16 60.8 6.3 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EEB08857.1 - 3.1e-08 33.9 7.0 3.1e-08 33.9 4.8 4.3 3 0 0 3 3 3 2 Domain of unknown function (DUF307) DUF4131 PF13567.1 EEB08857.1 - 0.0012 18.3 0.0 0.0012 18.3 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4131) Ribosomal_S8e PF01201.17 EEB08858.1 - 7.6e-50 168.4 1.2 8.8e-50 168.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EEB08858.1 - 0.021 15.0 0.2 0.085 13.1 0.0 1.9 2 0 0 2 2 2 0 Small acidic protein family RNA_pol_Rpb2_6 PF00562.23 EEB08859.1 - 3.2e-127 424.4 0.1 5.3e-127 423.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEB08859.1 - 1.2e-75 252.9 0.1 1.9e-75 252.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEB08859.1 - 3.1e-53 180.0 0.2 7.3e-53 178.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EEB08859.1 - 6.9e-28 96.2 0.5 2e-27 94.8 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.15 EEB08859.1 - 8.4e-28 96.4 0.0 2.3e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EEB08859.1 - 6.2e-23 80.3 0.0 1.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEB08859.1 - 1.2e-22 79.5 0.3 2.7e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 AMP-binding PF00501.23 EEB08860.1 - 2.5e-159 530.1 0.0 3.3e-80 269.5 0.0 4.9 4 1 1 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 EEB08860.1 - 4.9e-142 472.1 9.9 1e-29 103.3 0.0 7.8 7 1 0 7 7 7 6 Condensation domain PP-binding PF00550.20 EEB08860.1 - 2.2e-34 117.4 11.6 4.6e-10 39.6 0.0 6.8 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEB08860.1 - 3.6e-10 40.6 0.0 0.0018 19.1 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EEB08860.1 - 4.7 6.6 0.3 2.3e+02 1.1 0.0 3.3 6 0 0 6 6 6 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.1 EEB08861.1 - 2.1e-103 345.8 0.0 2.7e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEB08861.1 - 5.1e-16 58.8 0.0 3.3e-15 56.1 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEB08861.1 - 5.9e-10 39.5 0.0 3.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEB08861.1 - 0.0038 17.1 0.0 0.0084 16.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase A_amylase_inhib PF01356.14 EEB08861.1 - 0.17 11.7 0.4 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase inhibitor NUC153 PF08159.7 EEB08862.1 - 1.6e-11 43.5 1.6 3.2e-11 42.6 1.1 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EEB08862.1 - 0.015 15.2 0.8 30 4.7 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Pox_MCEL PF03291.11 EEB08863.1 - 6.7e-89 298.0 0.0 1.1e-88 297.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EEB08863.1 - 5e-11 42.4 0.0 7.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08863.1 - 8.7e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB08863.1 - 1.2e-08 35.2 0.0 4.8e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08863.1 - 1.3e-07 32.1 0.0 2.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB08863.1 - 4.4e-06 26.4 0.0 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08863.1 - 7.3e-06 26.3 0.0 1.9e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB08863.1 - 1.5e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEB08863.1 - 0.006 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 EEB08863.1 - 0.033 13.7 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EEB08863.1 - 0.046 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RCC1 PF00415.13 EEB08864.1 - 2.2e-26 91.8 2.2 6.8e-07 29.4 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EEB08864.1 - 1.6e-13 50.5 2.1 2.1e-08 34.1 0.1 3.3 3 0 0 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EEB08864.1 - 2.6e-09 37.0 0.0 1e-05 25.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEB08864.1 - 3.3e-08 33.8 0.1 1.9e-06 28.1 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB08864.1 - 1.7e-07 31.4 0.2 4.6e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 EEB08864.1 - 7.5e-07 28.6 8.5 9e-05 21.9 0.4 4.6 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EEB08864.1 - 0.0025 17.8 0.2 0.75 10.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EEB08864.1 - 0.0031 17.2 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat PAP1 PF08601.5 EEB08865.1 - 2.1e-24 86.8 34.9 2.9e-22 79.8 18.8 4.3 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EEB08865.1 - 2.8e-07 30.3 17.4 7.2e-07 29.0 12.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor Herpes_UL25 PF01499.11 EEB08865.1 - 0.0087 14.4 2.0 0.013 13.8 1.4 1.2 1 0 0 1 1 1 1 Herpesvirus UL25 family BCAS2 PF05700.6 EEB08865.1 - 0.072 12.5 8.1 0.14 11.5 5.6 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) bZIP_2 PF07716.10 EEB08865.1 - 1 9.2 18.5 22 4.9 11.7 2.3 1 1 1 2 2 2 0 Basic region leucine zipper V_ATPase_I PF01496.14 EEB08865.1 - 1.8 6.3 6.4 2.5 5.8 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNF2_N PF00176.18 EEB08866.2 - 3.2e-72 242.8 0.3 5.6e-72 242.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EEB08866.2 - 1e-20 73.1 0.4 1.1e-11 44.2 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EEB08866.2 - 6.4e-15 54.7 0.0 2.8e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SIR2 PF02146.12 EEB08867.2 - 2.7e-28 98.8 0.0 6.8e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 Sir2 family BmKX PF09132.5 EEB08867.2 - 0.0091 15.8 0.1 0.98 9.3 0.0 2.8 2 0 0 2 2 2 1 BmKX Zn-ribbon_8 PF09723.5 EEB08867.2 - 0.01 15.7 0.3 0.022 14.7 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TPP_enzyme_M PF00205.17 EEB08867.2 - 0.073 12.8 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FTA2 PF13095.1 EEB08868.1 - 4.6e-59 199.5 2.3 6e-59 199.1 1.6 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DNA_pol3_gamma3 PF12169.3 EEB08868.1 - 0.075 12.7 0.9 1.2 8.8 0.1 2.4 2 1 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III 5_3_exonuc PF01367.15 EEB08868.1 - 0.093 12.9 1.5 0.66 10.2 0.5 2.7 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold P2X_receptor PF00864.14 EEB08868.1 - 0.16 10.6 2.3 4.3 5.9 0.0 2.1 2 0 0 2 2 2 0 ATP P2X receptor Lectin_N PF03954.9 EEB08868.1 - 0.72 9.2 7.2 0.1 12.0 0.8 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain GrpE PF01025.14 EEB08868.1 - 0.93 9.0 6.5 2.1 7.8 4.5 1.7 1 1 0 1 1 1 0 GrpE DivIC PF04977.10 EEB08868.1 - 2.5 7.6 6.0 1.8 8.1 2.4 2.1 2 0 0 2 2 2 0 Septum formation initiator Acyltransferase PF01553.16 EEB08869.1 - 2.1e-07 30.4 0.0 3.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ssDNA-exonuc_C PF10141.4 EEB08869.1 - 0.12 11.9 0.1 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain FAD_binding_1 PF00667.15 EEB08870.1 - 2e-31 109.1 0.0 3.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEB08870.1 - 1.2e-12 48.3 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-PARP PF00645.13 EEB08871.1 - 9.7e-19 67.4 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Flavi_NS4A PF01350.12 EEB08871.1 - 0.15 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Sec10 PF07393.6 EEB08872.1 - 8e-129 430.9 10.8 8e-129 430.9 7.5 1.5 1 1 1 2 2 2 1 Exocyst complex component Sec10 YMF19 PF02326.10 EEB08872.1 - 0.48 11.0 9.2 1.7 9.2 0.1 4.4 4 0 0 4 4 4 0 Plant ATP synthase F0 Thioredoxin PF00085.15 EEB08874.1 - 6.6e-23 80.3 0.3 2.6e-22 78.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEB08874.1 - 1.8e-07 31.2 1.1 4e-05 23.6 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EEB08874.1 - 7.1e-07 29.4 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.1 EEB08874.1 - 0.0001 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 EEB08874.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EEB08874.1 - 0.0035 16.8 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EEB08874.1 - 0.0075 15.9 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEB08874.1 - 0.019 14.4 0.2 0.042 13.3 0.1 1.6 2 0 0 2 2 2 0 Redoxin BA14K PF07886.6 EEB08874.1 - 0.041 13.5 0.4 0.098 12.3 0.3 1.7 1 0 0 1 1 1 0 BA14K-like protein DUF605 PF04652.11 EEB08875.1 - 2.4e-44 152.3 10.9 2e-29 103.1 0.5 2.0 1 1 1 2 2 2 2 Vta1 like Imm22 PF15592.1 EEB08875.1 - 0.093 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 22 Fe-ADH PF00465.14 EEB08876.1 - 1.6e-56 191.5 1.3 2.3e-56 191.0 0.9 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEB08876.1 - 1.6e-37 129.1 0.8 2.1e-37 128.7 0.5 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EEB08876.1 - 1.2e-07 30.8 0.3 2.7e-07 29.8 0.2 1.5 1 1 0 1 1 1 1 3-dehydroquinate synthase Aldolase PF01081.14 EEB08876.1 - 0.044 12.9 0.1 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase ANF_receptor PF01094.23 EEB08876.1 - 0.051 12.3 0.0 0.14 10.9 0.0 1.7 1 1 0 1 1 1 0 Receptor family ligand binding region MBOAT PF03062.14 EEB08877.1 - 1.9e-30 106.0 25.7 1.9e-30 106.0 17.8 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EEB08877.1 - 0.00012 22.1 2.3 0.00012 22.1 1.6 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Pal1 PF08316.6 EEB08878.2 - 3.6e-33 114.9 3.2 1.8e-30 106.1 2.2 2.7 1 1 0 1 1 1 1 Pal1 cell morphology protein Arrestin_C PF02752.17 EEB08879.1 - 3.4e-10 40.1 4.7 7.3e-10 39.0 0.6 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 EEB08880.1 - 3e-36 124.8 0.0 4.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08880.1 - 2e-28 99.1 0.0 2.8e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB08880.1 - 0.041 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEB08880.1 - 0.057 13.1 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PMT PF02366.13 EEB08881.2 - 2.3e-82 276.0 22.1 2.3e-82 276.0 15.3 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEB08881.2 - 5.2e-18 65.2 0.0 7.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 MIR domain Glu_synthase PF01645.12 EEB08882.1 - 1.2e-159 531.1 0.0 3.7e-158 526.2 0.0 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EEB08882.1 - 4.8e-137 456.4 0.0 6.7e-137 456.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EEB08882.1 - 3.7e-117 390.6 0.0 6.6e-117 389.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EEB08882.1 - 1.3e-66 223.4 1.4 1.3e-66 223.4 1.0 1.7 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 EEB08882.1 - 7.5e-24 83.4 0.1 1.8e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EEB08882.1 - 2.2e-19 70.1 0.0 6.2e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB08882.1 - 6.6e-12 45.9 0.1 8.3e-05 22.7 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEB08882.1 - 2.4e-08 33.8 0.0 9.8e-08 31.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEB08882.1 - 2.3e-06 26.9 0.3 6.3e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EEB08882.1 - 5e-06 26.8 0.7 0.0002 21.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEB08882.1 - 1.5e-05 24.0 0.0 1.5e-05 24.0 0.0 1.8 2 0 0 2 2 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEB08882.1 - 3.5e-05 22.8 0.1 0.00015 20.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EEB08882.1 - 5.8e-05 22.3 0.2 0.00017 20.8 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EEB08882.1 - 8.5e-05 22.7 0.1 0.017 15.3 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EEB08882.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEB08882.1 - 0.00028 19.4 0.1 0.00028 19.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EEB08882.1 - 0.0018 17.4 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEB08882.1 - 0.018 14.7 0.0 0.32 10.7 0.0 2.9 2 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EEB08882.1 - 0.059 13.0 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EEB08882.1 - 0.061 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.13 EEB08882.1 - 0.061 12.1 2.2 0.21 10.4 1.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.15 EEB08882.1 - 0.1 12.7 0.1 35 4.4 0.0 3.7 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EEB08882.1 - 0.13 10.8 0.1 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GATase_6 PF13522.1 EEB08882.1 - 0.15 11.9 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 EEB08882.1 - 0.36 9.6 0.2 0.79 8.5 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EEB08882.1 - 0.36 9.6 3.1 0.47 9.2 0.1 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A HSP70 PF00012.15 EEB08883.1 - 1e-273 908.7 3.7 1.2e-273 908.6 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB08883.1 - 2.6e-16 59.1 0.0 5.1e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEB08883.1 - 0.00034 20.2 0.0 0.00078 19.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EEB08883.1 - 0.0024 17.0 0.9 0.039 13.0 0.1 2.6 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase Macoilin PF09726.4 EEB08883.1 - 0.011 14.1 0.3 0.012 13.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Phage_Mu_F PF04233.9 EEB08883.1 - 1.4 9.5 3.9 26 5.3 0.9 2.9 2 1 0 2 2 2 0 Phage Mu protein F like protein Smg4_UPF3 PF03467.10 EEB08884.1 - 7.3e-27 94.4 0.2 1.5e-26 93.5 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family FAM104 PF15434.1 EEB08885.1 - 0.045 13.9 0.1 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Family 104 DUF2363 PF10155.4 EEB08885.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) SUR7 PF06687.7 EEB08886.1 - 6.7e-15 55.2 17.3 1.1e-14 54.5 12.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family PAT1 PF09770.4 EEB08886.1 - 0.68 8.1 14.1 0.93 7.6 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Claudin_2 PF13903.1 EEB08886.1 - 3.9 7.1 14.2 0.052 13.2 3.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PAP2 PF01569.16 EEB08886.1 - 5.2 6.7 13.5 20 4.8 0.3 2.9 2 1 0 2 2 2 0 PAP2 superfamily Tetraspannin PF00335.15 EEB08886.1 - 7.6 5.7 12.1 14 4.8 8.4 1.4 1 0 0 1 1 1 0 Tetraspanin family Arif-1 PF06770.6 EEB08886.1 - 9.2 5.5 7.4 10 5.4 0.5 2.2 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) MBOAT PF03062.14 EEB08887.1 - 1e-36 126.7 25.6 1e-36 126.7 17.7 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EEB08887.1 - 0.0003 20.8 4.3 0.00073 19.5 3.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PAPS_reduct PF01507.14 EEB08888.1 - 1.7e-43 148.4 0.0 2.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.27 EEB08890.1 - 1.9e-21 75.0 4.3 4e-05 23.3 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Hira PF07569.6 EEB08890.1 - 0.0084 15.3 0.1 0.56 9.3 0.0 2.5 2 1 0 2 2 2 2 TUP1-like enhancer of split Nup160 PF11715.3 EEB08890.1 - 0.016 13.3 0.0 0.03 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ADH_N PF08240.7 EEB08891.2 - 5.9e-27 93.5 4.3 1.1e-26 92.7 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEB08891.2 - 6e-14 51.7 0.0 3.9e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EEB08891.2 - 2.7e-10 39.6 0.3 5.2e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 EEB08891.2 - 0.014 15.9 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EEB08891.2 - 0.07 12.2 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ResIII PF04851.10 EEB08892.2 - 4e-26 91.9 0.3 1.7e-24 86.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEB08892.2 - 2e-15 56.3 0.1 7.3e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08892.2 - 7e-15 54.9 0.0 1.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEB08892.2 - 0.0046 15.9 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EEB08892.2 - 0.011 15.8 0.0 0.056 13.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain TruB_N PF01509.13 EEB08893.1 - 4.9e-43 146.8 0.0 6.6e-42 143.1 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.17 EEB08893.1 - 0.037 13.8 0.1 0.076 12.8 0.1 1.7 1 1 0 1 1 1 0 RNA pseudouridylate synthase Ribosomal_L18p PF00861.17 EEB08894.1 - 2.2e-43 147.2 0.7 6e-43 145.8 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EEB08894.1 - 1.2e-31 109.1 4.8 1.2e-31 109.1 3.4 1.6 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EEB08894.1 - 0.027 14.4 0.3 0.31 11.0 0.2 2.5 1 1 0 1 1 1 0 Threonine synthase N terminus His_Phos_2 PF00328.17 EEB08895.1 - 1.2e-43 149.7 0.0 1.5e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.19 EEB08896.1 - 1.3e-121 406.3 28.9 1.5e-121 406.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB08896.1 - 6.9e-19 67.7 51.7 8.6e-18 64.1 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily U3_assoc_6 PF08640.6 EEB08897.1 - 1.1e-27 95.5 2.9 2.7e-27 94.3 2.0 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EEB08897.1 - 0.06 14.0 0.5 14 6.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LAGLIDADG_WhiA PF14527.1 EEB08897.1 - 0.15 11.9 2.8 0.41 10.5 1.9 1.8 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Coatomer_WDAD PF04053.9 EEB08898.1 - 4e-151 503.7 1.0 1.6e-150 501.7 0.1 2.2 1 1 2 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EEB08898.1 - 6.9e-47 155.7 17.9 5.1e-10 38.8 0.2 8.3 9 1 0 9 9 9 6 WD domain, G-beta repeat YmzC PF14157.1 EEB08898.1 - 0.0064 16.2 0.0 5.9 6.7 0.0 3.7 3 1 0 3 3 3 1 YmzC-like protein eIF2A PF08662.6 EEB08898.1 - 0.019 14.6 2.0 1.2 8.7 0.0 3.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PG_binding_2 PF08823.6 EEB08898.1 - 0.069 13.2 0.4 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TPR_19 PF14559.1 EEB08898.1 - 0.1 12.9 0.7 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 EEB08899.1 - 6.5e-12 44.9 0.0 1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB08899.1 - 2.1e-08 33.9 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08899.1 - 7.6e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08899.1 - 0.0008 19.1 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CCD PF07860.6 EEB08899.1 - 3.5 7.0 6.0 2.9 7.3 0.2 2.2 2 0 0 2 2 2 0 WisP family C-Terminal Region RIC3 PF15361.1 EEB08900.1 - 0.0039 17.4 0.1 0.0072 16.5 0.0 1.4 1 1 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 TATR PF03430.8 EEB08900.1 - 0.2 10.2 1.7 0.21 10.1 1.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator GPI-anchored PF10342.4 EEB08901.2 - 4.8e-18 65.4 7.7 4.8e-18 65.4 5.3 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFCD_C PF12612.3 EEB08902.2 - 1.3e-17 63.8 0.4 1.3e-17 63.8 0.3 4.4 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EEB08902.2 - 0.00023 21.3 3.5 0.98 9.7 0.0 4.9 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EEB08902.2 - 0.0045 17.4 6.1 5.8 7.5 0.2 5.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EEB08902.2 - 0.54 10.4 20.4 0.63 10.2 0.0 7.7 9 0 0 9 9 9 0 HEAT repeat Ndc80_HEC PF03801.8 EEB08904.1 - 2.4e-49 166.8 0.0 1.3e-48 164.4 0.0 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family Atg14 PF10186.4 EEB08904.1 - 0.0013 17.7 8.8 0.0013 17.7 6.1 3.3 2 1 1 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 EEB08904.1 - 0.0013 18.9 10.7 0.0013 18.9 7.4 4.8 2 1 1 3 3 2 1 Protein of unknown function (DUF904) Mnd1 PF03962.10 EEB08904.1 - 0.0034 17.0 37.0 0.015 14.9 6.3 3.2 2 1 1 3 3 3 2 Mnd1 family DUF4618 PF15397.1 EEB08904.1 - 0.011 15.0 36.8 0.014 14.7 6.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Spc7 PF08317.6 EEB08904.1 - 0.015 14.0 39.0 0.051 12.2 11.6 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein APG6 PF04111.7 EEB08904.1 - 0.047 12.7 39.5 0.17 10.9 7.6 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 IncA PF04156.9 EEB08904.1 - 0.16 11.5 49.1 0.11 12.0 8.8 3.4 2 1 1 3 3 3 0 IncA protein bZIP_1 PF00170.16 EEB08904.1 - 0.26 11.2 0.1 0.26 11.2 0.1 6.3 3 2 4 7 7 7 0 bZIP transcription factor GAS PF13851.1 EEB08904.1 - 0.26 10.4 42.8 0.14 11.3 4.7 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EEB08904.1 - 0.35 10.6 21.9 7.3 6.4 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Cluap1 PF10234.4 EEB08904.1 - 0.59 9.2 0.0 0.59 9.2 0.0 4.4 3 2 1 4 4 4 0 Clusterin-associated protein-1 Reo_sigmaC PF04582.7 EEB08904.1 - 0.61 9.2 19.1 0.6 9.2 2.4 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF812 PF05667.6 EEB08904.1 - 1.3 7.4 42.1 1.6 7.1 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF812) Sec8_exocyst PF04048.9 EEB08904.1 - 3.8 7.1 30.6 0.49 10.0 0.1 4.8 3 2 2 5 5 5 0 Sec8 exocyst complex component specific domain Occludin_ELL PF07303.8 EEB08904.1 - 6.4 7.5 25.4 2.7 8.7 3.6 4.8 2 2 2 5 5 5 0 Occludin homology domain FCH PF00611.18 EEB08905.2 - 3.4e-19 68.8 1.3 1.1e-18 67.1 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EEB08905.2 - 8.3e-11 41.1 0.1 1.5e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB08905.2 - 4.9e-10 38.8 0.1 8.6e-10 38.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEB08905.2 - 4.1e-09 35.7 0.1 7.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3449 PF11931.3 EEB08906.1 - 0.084 12.3 0.4 0.092 12.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Tir_receptor_C PF07489.6 EEB08906.1 - 0.2 11.4 2.5 0.24 11.1 1.7 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Curto_V3 PF07436.6 EEB08906.1 - 0.22 11.6 0.8 0.3 11.2 0.5 1.2 1 0 0 1 1 1 0 Curtovirus V3 protein CTK3 PF12243.3 EEB08907.1 - 0.003 17.1 0.1 0.0061 16.1 0.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CH PF00307.26 EEB08908.1 - 0.00014 21.8 2.7 0.0011 19.0 0.0 3.0 3 0 0 3 3 3 1 Calponin homology (CH) domain L27 PF02828.11 EEB08908.1 - 0.074 12.7 0.1 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 L27 domain DEAD PF00270.24 EEB08909.1 - 1.2e-47 161.5 0.0 2e-46 157.5 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08909.1 - 2.3e-25 88.2 0.3 8.1e-25 86.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EEB08909.1 - 0.0067 15.5 0.0 0.0067 15.5 0.0 3.4 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EEB08909.1 - 0.011 15.8 0.2 0.078 13.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EEB08909.1 - 0.057 13.1 0.4 0.34 10.6 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain Senescence PF06911.7 EEB08909.1 - 0.57 9.8 12.7 1 8.9 8.8 1.4 1 0 0 1 1 1 0 Senescence-associated protein GAGA_bind PF06217.7 EEB08909.1 - 2.8 7.8 15.1 4.9 7.0 10.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RRN9 PF10680.4 EEB08911.1 - 0.0038 16.9 11.6 0.017 14.8 6.4 2.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RNase_PH PF01138.16 EEB08912.1 - 2.8e-22 79.4 0.0 4e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEB08912.1 - 2e-06 27.6 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Diphthamide_syn PF01866.12 EEB08913.1 - 1e-66 225.2 0.0 1.3e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MoeZ_MoeB PF05237.8 EEB08913.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 MoeZ/MoeB domain DUF3020 PF11223.3 EEB08914.1 - 5.8e-21 74.6 5.0 5.8e-21 74.6 3.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) WD40 PF00400.27 EEB08915.1 - 4.1e-16 58.1 6.3 1.2e-06 28.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat PC_rep PF01851.17 EEB08916.1 - 1.3e-40 135.3 25.2 1.9e-06 27.7 0.1 9.7 11 0 0 11 11 11 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEB08916.1 - 1.6e-14 53.9 3.8 1.7e-09 37.8 0.1 4.2 4 0 0 4 4 4 2 HEAT repeats Cnd3 PF12719.2 EEB08916.1 - 0.0016 17.4 1.2 0.0083 15.1 0.0 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EEB08916.1 - 0.0019 18.1 1.5 0.24 11.5 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EEB08916.1 - 0.0021 18.4 5.2 0.053 14.0 0.1 4.5 3 1 2 5 5 5 3 HEAT-like repeat HEAT_PBS PF03130.11 EEB08916.1 - 0.013 15.8 0.8 8.2 7.2 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF1675 PF07897.6 EEB08916.1 - 0.019 14.8 1.4 0.03 14.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Vfa1 PF08432.5 EEB08916.1 - 0.18 11.8 12.0 5.5 6.9 7.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 EEB08916.1 - 1.2 9.0 10.1 2.1 8.1 7.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MSA_2 PF00985.12 EEB08916.1 - 1.5 8.9 7.8 2.9 8.0 5.4 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family IMS PF00817.15 EEB08917.2 - 1.1e-47 161.5 0.9 5.2e-47 159.3 0.3 2.2 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EEB08917.2 - 1.6e-22 79.7 0.3 3.3e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEB08917.2 - 6e-06 26.0 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Ribophorin_II PF05817.9 EEB08918.2 - 8e-11 40.8 0.1 1e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S8 PF00410.14 EEB08919.1 - 2.5e-22 79.0 0.0 3e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Translin PF01997.11 EEB08920.1 - 2.3e-46 157.9 0.2 2.7e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Translin family LAG1-DNAbind PF09271.6 EEB08921.1 - 5.8e-25 88.4 4.1 3.4e-23 82.6 2.8 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EEB08921.1 - 5e-16 58.8 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF3835 PF12927.2 EEB08922.1 - 3.6e-18 66.2 8.8 4.9e-15 56.2 0.1 7.0 7 2 2 9 9 9 2 Domain of unknown function (DUF3835) tRNA-synt_2 PF00152.15 EEB08923.1 - 7.9e-113 376.6 0.0 1e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EEB08923.1 - 6.3e-06 25.8 1.0 0.00021 20.9 0.4 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EEB08923.1 - 0.0013 17.9 0.9 0.22 10.6 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EEB08923.1 - 0.0038 17.0 0.0 0.012 15.3 0.0 1.9 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain Glyco_transf_34 PF05637.7 EEB08924.1 - 4.5e-72 242.3 1.5 7.5e-72 241.6 1.0 1.4 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family EIID-AGA PF03613.9 EEB08924.1 - 0.052 12.4 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component UPF0016 PF01169.14 EEB08925.1 - 2.7e-39 133.1 24.8 2.5e-22 78.7 3.9 2.6 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF204 PF02659.10 EEB08925.1 - 0.76 9.9 16.8 0.62 10.2 2.5 4.1 3 2 0 3 3 3 0 Domain of unknown function DUF Zip PF02535.17 EEB08925.1 - 6.1 5.7 10.0 0.67 8.8 2.5 2.4 2 1 1 3 3 3 0 ZIP Zinc transporter DUF2254 PF10011.4 EEB08925.1 - 6.3 5.1 6.5 0.42 9.0 0.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) YEATS PF03366.11 EEB08926.1 - 2.6e-32 110.3 1.3 4.3e-32 109.6 0.9 1.3 1 0 0 1 1 1 1 YEATS family ILVD_EDD PF00920.16 EEB08927.1 - 5.1e-208 691.7 0.2 6e-208 691.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Med20 PF08612.6 EEB08928.2 - 1.4e-16 60.3 0.6 3.7e-16 58.9 0.3 1.7 1 1 1 2 2 2 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex P16-Arc PF04699.9 EEB08929.1 - 2.5e-40 137.9 0.0 2.8e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 EEB08929.1 - 0.026 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family DnaB_2 PF07261.6 EEB08929.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment CBFD_NFYB_HMF PF00808.18 EEB08930.2 - 5e-07 29.6 0.1 6.5e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EEB08930.2 - 0.0027 17.6 1.2 0.01 15.8 0.8 1.8 1 1 0 1 1 1 1 Centromere kinetochore component W Histone PF00125.19 EEB08930.2 - 0.0074 16.3 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MRP-S26 PF14943.1 EEB08930.2 - 0.018 14.6 0.1 0.021 14.3 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 AAA_32 PF13654.1 EEB08930.2 - 0.038 12.6 0.1 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain PUF PF00806.14 EEB08931.2 - 6e-57 186.0 13.5 2.3e-08 33.0 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat He_PIG_assoc PF10632.4 EEB08931.2 - 0.16 11.3 0.1 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase CPL PF08144.6 EEB08931.2 - 0.18 11.6 0.6 1.3 8.8 0.0 2.6 2 2 1 3 3 3 0 CPL (NUC119) domain Peptidase_M28 PF04389.12 EEB08932.1 - 7.7e-32 110.4 0.0 1.3e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEB08932.1 - 2.6e-05 23.8 0.0 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF2273 PF10031.4 EEB08932.1 - 0.17 11.5 8.4 0.021 14.4 1.8 2.5 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF676 PF05057.9 EEB08933.1 - 4.7e-46 156.8 0.0 7.5e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EEB08933.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) TFIIS_C PF01096.13 EEB08934.1 - 2.9e-17 62.0 6.4 4.7e-17 61.3 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEB08934.1 - 1.3e-14 53.6 8.3 7.8e-12 44.6 0.4 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 EEB08934.1 - 5.6e-05 22.8 9.6 0.00085 19.0 0.4 2.9 2 1 1 3 3 3 1 Double zinc ribbon Lar_restr_allev PF14354.1 EEB08934.1 - 0.0017 18.5 1.5 0.0017 18.5 1.0 2.6 1 1 1 2 2 2 1 Restriction alleviation protein Lar zf-TFIIB PF13453.1 EEB08934.1 - 0.002 17.2 7.7 0.003 16.7 0.6 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger zf-ribbon_3 PF13248.1 EEB08934.1 - 0.0039 16.3 10.9 0.96 8.7 1.2 3.9 3 1 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EEB08934.1 - 0.007 15.8 11.7 0.6 9.6 0.4 3.7 3 1 1 4 4 4 2 zinc-ribbon domain zf-DNA_Pol PF08996.5 EEB08934.1 - 0.0081 15.5 2.9 0.044 13.1 0.5 2.1 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger C1_1 PF00130.17 EEB08934.1 - 0.011 15.3 0.5 0.011 15.3 0.4 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Terminase_GpA PF05876.7 EEB08934.1 - 0.019 13.3 0.4 0.03 12.6 0.3 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HypA PF01155.14 EEB08934.1 - 0.037 13.6 7.0 0.59 9.8 0.1 2.9 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C4pol PF14260.1 EEB08934.1 - 0.042 13.8 4.7 0.098 12.6 0.1 2.4 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta RecR PF02132.10 EEB08934.1 - 0.056 12.8 0.9 0.056 12.8 0.6 2.9 3 0 0 3 3 3 0 RecR protein Prok-RING_1 PF14446.1 EEB08934.1 - 0.084 12.6 5.7 0.82 9.4 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 VP_N-CPKC PF11475.3 EEB08934.1 - 0.11 12.0 6.5 2 8.0 0.1 3.1 3 0 0 3 3 2 0 Virion protein N terminal domain zinc_ribbon_4 PF13717.1 EEB08934.1 - 0.11 12.2 11.5 9.3 6.0 0.5 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EEB08934.1 - 0.12 12.2 9.6 0.23 11.2 0.5 2.9 2 1 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 EEB08934.1 - 0.13 11.9 6.5 1.2 8.8 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Rpr2 PF04032.11 EEB08934.1 - 0.15 11.9 4.1 1.1 9.1 1.8 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.1 EEB08934.1 - 0.27 11.6 12.2 2.3 8.7 1.0 3.7 4 0 0 4 4 3 0 C2H2-type zinc finger zf-FPG_IleRS PF06827.9 EEB08934.1 - 0.31 10.7 13.6 4 7.1 0.6 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Mu-like_Com PF10122.4 EEB08934.1 - 0.32 10.0 3.6 4.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com Zn_Tnp_IS1595 PF12760.2 EEB08934.1 - 0.34 10.7 10.5 0.11 12.3 1.3 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEB08934.1 - 0.35 10.5 12.2 12 5.6 0.6 4.1 4 0 0 4 4 4 0 zinc-ribbon domain c-SKI_SMAD_bind PF08782.5 EEB08934.1 - 0.37 10.9 2.2 0.53 10.4 0.1 2.1 1 1 2 3 3 3 0 c-SKI Smad4 binding domain Zn_ribbon_recom PF13408.1 EEB08934.1 - 0.4 10.9 6.7 4.9 7.4 0.3 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-AN1 PF01428.11 EEB08934.1 - 0.46 10.3 7.4 5.1 7.0 0.5 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf-Di19 PF05605.7 EEB08934.1 - 0.67 10.1 7.0 13 6.0 0.0 3.0 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.7 EEB08934.1 - 0.68 9.3 13.5 3.1 7.1 0.0 3.4 3 1 1 4 4 4 0 TFIIB zinc-binding Ribosomal_S27e PF01667.12 EEB08934.1 - 0.69 9.5 0.1 0.69 9.5 0.1 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 PolC_DP2 PF03833.8 EEB08934.1 - 0.7 7.4 4.4 0.19 9.3 0.3 1.7 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 C1_4 PF07975.7 EEB08934.1 - 0.85 9.6 9.1 13 5.9 1.5 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain Baculo_LEF5_C PF11792.3 EEB08934.1 - 1.2 8.6 0.1 1.2 8.6 0.0 3.4 3 1 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain PHD PF00628.24 EEB08934.1 - 1.4 8.6 9.0 0.41 10.3 0.5 2.8 2 1 0 2 2 2 0 PHD-finger PhnA_Zn_Ribbon PF08274.7 EEB08934.1 - 1.8 8.3 12.6 11 5.8 2.2 3.8 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-LITAF-like PF10601.4 EEB08934.1 - 2.1 8.2 9.8 2.6 7.9 0.0 3.9 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EEB08934.1 - 2.2 7.8 5.9 11 5.6 0.1 3.0 3 0 0 3 3 3 0 InsA N-terminal domain Stc1 PF12898.2 EEB08934.1 - 2.5 8.2 6.2 0.67 10.0 0.3 2.2 1 1 1 2 2 2 0 Stc1 domain Ogr_Delta PF04606.7 EEB08934.1 - 2.5 7.8 8.2 1.4 8.6 1.6 3.0 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger DUF3797 PF12677.2 EEB08934.1 - 2.8 7.6 10.8 0.63 9.7 0.9 3.3 3 1 1 4 4 3 0 Domain of unknown function (DUF3797) UPF0547 PF10571.4 EEB08934.1 - 2.9 7.6 11.1 12 5.6 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 EEB08934.1 - 2.9 7.7 9.6 5.5 6.9 0.5 2.7 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.1 EEB08934.1 - 2.9 7.6 12.2 9.7 5.9 2.8 3.8 3 1 0 3 3 3 0 Nudix N-terminal Rubredoxin PF00301.15 EEB08934.1 - 4.5 7.2 8.4 36 4.3 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin Zn-ribbon_8 PF09723.5 EEB08934.1 - 5.6 7.0 15.3 5.4 7.0 0.4 3.8 2 2 1 4 4 4 0 Zinc ribbon domain zf-HIT PF04438.11 EEB08934.1 - 5.8 6.6 14.7 7.4 6.3 0.4 3.8 4 0 0 4 4 4 0 HIT zinc finger zf-ISL3 PF14690.1 EEB08934.1 - 7.7 6.6 6.9 7.1 6.7 0.1 3.2 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4_Topoisom PF01396.14 EEB08934.1 - 8.7 5.9 14.8 7.3 6.1 5.0 3.8 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Acyl_transf_1 PF00698.16 EEB08935.2 - 2.9e-65 220.6 0.0 2.7e-63 214.2 0.0 3.0 2 1 1 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 EEB08935.2 - 4.8e-30 103.1 0.1 1.7e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EEB08935.2 - 1.7e-27 95.1 1.3 1.5e-26 92.2 0.1 2.9 3 0 0 3 3 3 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEB08935.2 - 1.5e-18 66.8 0.0 3.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EEB08935.2 - 0.0024 17.0 0.0 0.18 10.8 0.0 2.4 2 0 0 2 2 2 1 Nitronate monooxygenase Brix PF04427.13 EEB08936.1 - 1.8e-37 128.8 0.1 2.6e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain URO-D PF01208.12 EEB08937.1 - 1.2e-124 415.7 0.0 1.3e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) cNMP_binding PF00027.24 EEB08938.1 - 3.5e-38 129.2 0.1 2.8e-18 65.5 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EEB08938.1 - 2.7e-16 60.1 2.6 5.6e-15 55.8 1.8 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase Cupin_2 PF07883.6 EEB08938.1 - 0.11 12.0 0.1 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Cupin domain DUF21 PF01595.15 EEB08939.2 - 8.5e-34 116.4 0.2 1.4e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EEB08939.2 - 0.00022 20.9 0.0 0.063 13.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain Dicty_REP PF05086.7 EEB08939.2 - 0.39 8.4 3.1 0.52 8.0 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Got1 PF04178.7 EEB08940.1 - 1.3e-13 51.1 16.3 1.4e-13 50.9 11.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Anoctamin PF04547.7 EEB08940.1 - 0.29 9.7 2.1 0.6 8.6 1.4 1.5 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF308 PF03729.8 EEB08940.1 - 0.35 10.8 18.2 0.28 11.2 7.8 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF981 PF06168.6 EEB08940.1 - 1.8 8.3 9.2 3.8 7.2 6.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF981) Rhodanese PF00581.15 EEB08941.1 - 8e-26 90.6 0.0 1.5e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SNF2_N PF00176.18 EEB08942.1 - 2.3e-70 236.7 0.0 4.9e-70 235.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB08942.1 - 4.8e-14 51.9 0.0 1.7e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08942.1 - 0.053 13.0 0.0 9.9 5.6 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Allexi_40kDa PF05549.6 EEB08942.1 - 2.4 7.3 5.1 1.7 7.8 1.2 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein efThoc1 PF11957.3 EEB08943.1 - 7.1e-82 275.4 10.5 7.1e-82 275.4 7.3 2.0 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor DUF3092 PF11289.3 EEB08943.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) CHCH PF06747.8 EEB08944.1 - 3.8e-06 26.6 6.6 5.4e-06 26.1 4.6 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EEB08944.1 - 0.025 14.7 2.9 0.047 13.8 2.0 1.4 1 0 0 1 1 1 0 GCK domain CENP-B_dimeris PF09026.5 EEB08944.1 - 0.13 12.5 2.1 0.15 12.3 1.4 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cmc1 PF08583.5 EEB08944.1 - 0.89 9.3 5.2 1.2 9.0 0.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like RRM_5 PF13893.1 EEB08945.1 - 1.2e-10 41.0 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB08945.1 - 4.6e-07 29.3 0.1 8.6e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB08945.1 - 4e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB08945.1 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EEB08945.1 - 0.013 15.3 1.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DSHCT PF08148.7 EEB08946.2 - 9.5e-57 191.1 0.5 9.5e-57 191.1 0.3 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EEB08946.2 - 1.4e-19 70.2 0.1 3.8e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB08946.2 - 2.7e-06 27.1 0.0 7.7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EEB08946.2 - 0.00083 18.5 5.0 0.0015 17.7 1.3 2.7 2 1 0 2 2 2 1 rRNA-processing arch domain ResIII PF04851.10 EEB08946.2 - 0.027 14.3 1.1 0.32 10.7 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit GPI2 PF06432.6 EEB08947.1 - 3.5e-92 308.7 23.3 4e-92 308.5 16.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SMC_Nse1 PF07574.8 EEB08948.1 - 4.7e-19 68.8 1.7 5.2e-17 62.1 1.2 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EEB08948.1 - 0.023 14.6 13.3 0.072 13.0 9.2 1.8 1 1 0 1 1 1 0 RING-like domain Erf4 PF10256.4 EEB08948.1 - 0.14 12.0 0.4 6.4 6.6 0.3 2.9 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family zf-RING_4 PF14570.1 EEB08948.1 - 1.8 8.2 14.5 1.1 8.9 7.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EEB08948.1 - 4.1 7.2 6.1 15 5.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Cpn60_TCP1 PF00118.19 EEB08950.1 - 6.8e-146 486.6 15.3 7.7e-146 486.5 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_E PF05680.7 EEB08951.1 - 3.7e-11 42.8 0.3 4.4e-11 42.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 EEB08951.1 - 0.0076 16.3 0.8 0.011 15.7 0.5 1.5 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF2605 PF10792.4 EEB08951.1 - 0.0082 15.7 0.5 0.012 15.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2605) DUF349 PF03993.7 EEB08951.1 - 1.1 9.4 5.7 1.7 8.8 3.9 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) A_deaminase PF00962.17 EEB08952.1 - 2.2e-116 388.4 0.0 3.1e-116 387.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1776 PF08643.5 EEB08953.1 - 2.6e-36 125.3 0.0 4.5e-32 111.3 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) ParBc PF02195.13 EEB08954.1 - 9.6e-09 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Pkinase PF00069.20 EEB08955.2 - 1.5e-56 191.4 0.0 2e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB08955.2 - 2.2e-27 95.7 0.1 2.2e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEB08955.2 - 7e-05 21.9 0.0 0.00014 20.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EEB08955.2 - 0.0022 17.3 0.4 0.0038 16.6 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EEB08955.2 - 0.014 15.1 0.0 0.73 9.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB08955.2 - 0.059 12.4 0.2 0.14 11.2 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family STT3 PF02516.9 EEB08956.2 - 3e-140 468.4 32.2 3.9e-140 468.0 22.3 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit NIF PF03031.13 EEB08957.1 - 3.5e-20 72.2 0.3 6e-20 71.5 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AbbA_antirepres PF14156.1 EEB08957.1 - 0.012 15.2 1.3 0.017 14.7 0.1 1.8 2 0 0 2 2 2 0 Antirepressor AbbA Noelin-1 PF12308.3 EEB08957.1 - 0.034 13.9 1.5 6.3 6.6 0.3 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein zf-AN1 PF01428.11 EEB08958.1 - 2.7e-10 39.9 5.0 4.7e-10 39.1 3.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EEB08958.1 - 0.051 13.7 1.5 0.095 12.9 1.0 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DUF3123 PF11321.3 EEB08958.1 - 0.68 10.2 5.5 0.21 11.8 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DS PF01916.12 EEB08959.1 - 2.7e-139 463.4 0.0 3.1e-139 463.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Acetyltransf_1 PF00583.19 EEB08960.1 - 6.6e-19 67.7 0.1 8.9e-19 67.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB08960.1 - 4.9e-12 45.8 0.1 7.1e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB08960.1 - 4.2e-10 39.2 0.1 6.1e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEB08960.1 - 1.1e-09 38.4 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEB08960.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEB08960.1 - 3.9e-08 33.3 0.1 4.9e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB08960.1 - 4.6e-07 29.7 0.0 7.2e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEB08960.1 - 5e-07 29.9 0.1 9.1e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEB08960.1 - 0.0017 18.1 0.0 0.0017 18.1 0.0 2.0 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EEB08960.1 - 0.085 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EEB08961.2 - 3.7e-31 108.2 34.0 1.2e-20 73.5 5.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEB08961.2 - 1.4e-18 66.7 43.5 1.5e-15 56.7 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.15 EEB08961.2 - 0.16 11.6 2.2 0.78 9.4 0.0 3.1 2 0 0 2 2 2 0 Syndecan domain Gate PF07670.9 EEB08961.2 - 6.6 6.6 9.1 0.42 10.5 0.7 2.8 3 0 0 3 3 3 0 Nucleoside recognition MFS_1 PF07690.11 EEB08962.1 - 4.3e-37 127.6 14.5 4.3e-37 127.6 10.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF21 PF01595.15 EEB08962.1 - 0.53 9.5 5.2 9.4 5.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF21 AA_permease_2 PF13520.1 EEB08963.1 - 9.5e-57 192.4 52.4 1.1e-56 192.1 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB08963.1 - 1.9e-18 66.0 36.8 2.6e-18 65.6 25.5 1.3 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.16 EEB08964.2 - 1.8e-121 405.3 24.7 2.1e-121 405.1 17.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.1 EEB08964.2 - 0.6 10.2 13.9 0.17 12.0 1.5 3.5 3 1 0 3 3 3 0 Transmembrane protein Cyclin_N PF00134.18 EEB08965.1 - 2.2e-45 153.3 0.2 1e-44 151.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEB08965.1 - 6.6e-33 113.1 0.3 1.5e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain KH_1 PF00013.24 EEB08966.1 - 0.006 16.2 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 EEB08966.1 - 0.02 14.5 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 KH domain BRCT PF00533.21 EEB08967.1 - 1.7e-30 105.0 0.7 2.3e-06 27.6 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEB08967.1 - 7.4e-22 76.9 2.3 1.5e-13 50.3 0.0 4.8 5 0 0 5 5 5 3 twin BRCT domain Baculo_PP31 PF05311.6 EEB08968.1 - 0.017 14.4 9.5 0.023 13.9 6.4 1.4 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) HOOK PF05622.7 EEB08968.1 - 0.041 11.7 17.9 0.05 11.4 12.4 1.1 1 0 0 1 1 1 0 HOOK protein Jnk-SapK_ap_N PF09744.4 EEB08968.1 - 0.55 10.2 15.9 0.026 14.5 6.1 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.14 EEB08968.1 - 0.7 7.6 12.9 0.86 7.3 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 EEB08968.1 - 2.9 7.3 21.8 1.7 8.1 1.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Selenoprotein_S PF06936.6 EEB08968.1 - 4.1 6.8 7.4 3.5 7.1 4.3 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) DUF1664 PF07889.7 EEB08968.1 - 4.8 6.9 8.7 1.4 8.7 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3340 PF11818.3 EEB08968.1 - 5.2 7.0 12.6 3.2 7.7 7.2 1.6 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) RPN7 PF10602.4 EEB08969.1 - 3.5e-50 169.8 2.0 7.5e-50 168.7 1.4 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEB08969.1 - 4.6e-16 59.0 0.1 1.9e-15 57.0 0.0 2.1 2 1 0 2 2 2 1 PCI domain Cep57_CLD_2 PF14197.1 EEB08969.1 - 0.003 17.4 0.7 0.0087 15.9 0.5 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 HTH_DeoR PF08220.7 EEB08969.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Aminotran_1_2 PF00155.16 EEB08970.1 - 3.4e-37 128.2 0.0 4.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DDE_Tnp_IS66_C PF13817.1 EEB08970.1 - 0.15 12.0 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element PEX11 PF05648.9 EEB08971.2 - 1.9e-37 128.7 2.0 2.1e-37 128.5 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CBM_X PF06204.6 EEB08971.2 - 0.02 14.3 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative carbohydrate binding domain SNF2_N PF00176.18 EEB08972.1 - 1.9e-80 269.8 0.8 2.9e-80 269.2 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEB08972.1 - 3.2e-14 52.5 0.0 1.6e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEB08972.1 - 5.6e-05 22.6 0.0 0.00022 20.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DZR PF12773.2 EEB08972.1 - 0.2 11.4 2.6 0.51 10.1 1.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon SLX9 PF15341.1 EEB08972.1 - 1.9 8.9 14.0 2.6 8.4 4.6 2.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Nup84_Nup100 PF04121.8 EEB08973.1 - 2e-154 515.0 7.6 2.3e-154 514.7 5.2 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Aminotran_4 PF01063.14 EEB08974.2 - 4.7e-24 85.1 0.0 6.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV AAA PF00004.24 EEB08975.2 - 1.3e-08 35.1 0.0 3.5e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB08975.2 - 0.0088 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEB08975.2 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EEB08975.2 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-RING_2 PF13639.1 EEB08976.2 - 2.5e-10 40.0 11.6 2e-08 33.8 9.1 2.5 1 1 1 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EEB08976.2 - 3.5e-08 33.4 4.4 7.1e-08 32.4 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EEB08976.2 - 7e-07 28.8 6.8 0.0011 18.6 2.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB08976.2 - 3.8e-06 26.4 7.1 7.5e-06 25.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB08976.2 - 5.1e-06 26.4 8.1 6.7e-05 22.8 3.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB08976.2 - 3.2e-05 23.5 8.0 0.0005 19.7 6.2 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEB08976.2 - 0.00022 20.9 5.1 0.0018 18.0 2.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TrbE PF11100.3 EEB08976.2 - 0.13 12.1 8.5 0.26 11.1 0.1 3.7 3 1 1 4 4 4 0 Conjugal transfer protein TrbE EII-Sor PF03609.9 EEB08976.2 - 0.14 11.4 8.8 0.15 11.3 0.6 2.6 2 1 0 2 2 2 0 PTS system sorbose-specific iic component zf-RING_4 PF14570.1 EEB08976.2 - 0.4 10.3 3.4 1.1 8.8 0.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EEB08976.2 - 0.4 10.2 3.7 15 5.1 0.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 EEB08976.2 - 0.47 10.0 4.0 1.1 8.8 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEB08976.2 - 2.3 7.9 7.3 16 5.2 5.1 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EEB08976.2 - 7.8 6.0 14.2 0.78 9.2 0.1 2.8 3 0 0 3 3 3 0 P-11 zinc finger Pyr_redox_2 PF07992.9 EEB08977.2 - 3.4e-24 85.8 0.1 2.2e-13 50.5 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB08977.2 - 2.5e-10 40.6 0.7 7e-10 39.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB08977.2 - 0.001 19.1 0.0 0.02 14.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase RNase_PH PF01138.16 EEB08978.1 - 1.5e-20 73.8 0.1 2.4e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3927 PF13064.1 EEB08978.1 - 0.11 12.0 0.1 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) AFG1_ATPase PF03969.11 EEB08979.2 - 5.5e-80 268.8 0.1 4.9e-75 252.6 0.0 2.5 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EEB08979.2 - 7.2e-05 22.8 0.5 0.19 11.6 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEB08979.2 - 0.0031 17.6 0.1 0.022 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEB08979.2 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EEB08979.2 - 0.11 12.1 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EEB08979.2 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EEB08979.2 - 0.21 11.8 0.9 2.9 8.2 0.0 2.7 3 1 0 4 4 4 0 ABC transporter FKBP_C PF00254.23 EEB08980.2 - 6.1e-33 112.7 0.0 7e-33 112.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FTHFS PF01268.14 EEB08981.1 - 5.2e-261 866.5 0.0 6.4e-261 866.2 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EEB08981.1 - 3.4e-70 234.2 2.0 4.7e-70 233.8 0.4 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EEB08981.1 - 1.2e-38 131.6 0.1 1.5e-37 128.1 0.1 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AP_endonuc_2 PF01261.19 EEB08981.1 - 0.026 13.8 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel GTP_EFTU PF00009.22 EEB08982.1 - 3.3e-57 192.9 0.8 5.3e-57 192.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEB08982.1 - 3.7e-37 126.4 0.0 9.2e-37 125.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEB08982.1 - 1.9e-16 59.9 2.0 1.9e-16 59.9 1.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEB08982.1 - 1.4e-05 24.5 0.5 4e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEB08982.1 - 0.00098 19.0 0.3 0.0033 17.3 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_31 PF13847.1 EEB08984.1 - 6.3e-20 71.3 0.0 8.9e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB08984.1 - 8.5e-15 55.3 0.0 1.6e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB08984.1 - 2e-11 43.9 0.2 3.4e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB08984.1 - 4.9e-09 36.5 0.1 6.3e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEB08984.1 - 1.6e-07 30.8 0.0 7.7e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EEB08984.1 - 1.2e-06 28.3 0.0 2.6e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEB08984.1 - 5.1e-06 26.2 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB08984.1 - 5.5e-06 26.6 0.0 8.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB08984.1 - 1.4e-05 25.4 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 EEB08984.1 - 0.0025 16.7 0.0 0.0031 16.4 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EEB08984.1 - 0.0063 15.6 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EEB08984.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 EEB08984.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_28 PF02636.12 EEB08984.1 - 0.04 13.2 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 EEB08984.1 - 0.067 12.0 0.0 0.77 8.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_2 PF00891.13 EEB08984.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Ribosomal_L13 PF00572.13 EEB08985.1 - 4.3e-27 94.6 0.0 7.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 EEB08985.1 - 0.097 12.2 0.2 0.18 11.3 0.2 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain RNA_pol_3_Rpc31 PF11705.3 EEB08986.1 - 4.1e-34 118.5 13.0 4.7e-34 118.3 9.0 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.5 EEB08986.1 - 6 7.4 14.7 2.1 8.9 8.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) UAA PF08449.6 EEB08987.1 - 2.7e-80 269.5 16.9 3.2e-80 269.3 11.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEB08987.1 - 1.9e-10 40.8 6.9 1.9e-10 40.8 4.8 3.4 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EEB08987.1 - 2.7e-08 34.0 22.3 8.6e-06 25.9 3.0 4.0 1 1 2 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EEB08987.1 - 5e-07 29.0 5.5 0.004 16.2 0.1 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EEB08987.1 - 0.00023 20.8 19.3 0.00094 18.8 5.6 2.6 2 2 0 2 2 2 2 Triose-phosphate Transporter family RRM_1 PF00076.17 EEB08988.2 - 0.0048 16.4 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.15 EEB08989.1 - 9.4e-09 34.5 7.2 1.6e-08 33.8 4.4 1.9 1 1 1 2 2 2 1 Ribosomal protein S21 PigN PF04987.9 EEB08990.1 - 4e-120 401.4 41.5 5e-120 401.1 28.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EEB08990.1 - 2.9e-07 30.1 0.4 0.0012 18.2 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEB08990.1 - 3.2e-06 26.5 0.1 4.7e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EEB08990.1 - 7.2e-06 25.5 0.1 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 EEB08990.1 - 0.33 9.5 0.0 0.55 8.8 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Rhodanese PF00581.15 EEB08991.1 - 2.1e-12 47.3 0.0 7.4e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Alpha_E1_glycop PF01589.11 EEB08991.1 - 0.045 12.0 0.0 0.055 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein E1-E2_ATPase PF00122.15 EEB08992.1 - 1.1e-64 217.6 3.1 2.3e-64 216.5 2.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEB08992.1 - 4.7e-31 107.7 6.9 4.7e-31 107.7 4.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEB08992.1 - 2.5e-28 99.9 0.0 1.7e-23 84.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB08992.1 - 1.4e-19 69.8 0.0 3.5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEB08992.1 - 3.7e-15 55.1 0.0 9.7e-15 53.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEB08992.1 - 8.4e-13 48.9 0.0 2.9e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEB08992.1 - 0.0047 16.5 1.8 0.0071 15.9 0.8 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_ligase_OB PF03120.11 EEB08992.1 - 0.067 12.8 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Ribosomal_S17e PF00833.13 EEB08994.1 - 1e-60 202.8 1.0 1.2e-60 202.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 AIG2 PF06094.7 EEB08994.1 - 0.021 15.3 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 AIG2-like family DUF3016 PF11454.3 EEB08994.1 - 0.051 13.1 0.8 0.44 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3016) DENN PF02141.16 EEB08994.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 DENN (AEX-3) domain HIT PF01230.18 EEB08995.1 - 2.2e-25 89.0 0.1 5.3e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEB08995.1 - 2.6e-09 37.3 0.0 4.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1412 PF07203.6 EEB08995.1 - 0.044 13.6 0.2 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1412) DUF2415 PF10313.4 EEB08996.1 - 2.3e-11 43.1 0.0 1.1e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EEB08996.1 - 0.0043 16.8 12.1 0.025 14.4 0.2 5.1 6 1 0 6 6 6 1 WD domain, G-beta repeat Kelch_6 PF13964.1 EEB08996.1 - 0.19 11.9 1.6 2.5 8.4 0.1 3.3 4 0 0 4 4 4 0 Kelch motif DNA_pol_A_exo1 PF01612.15 EEB08997.1 - 3e-18 65.9 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF3210 PF11489.3 EEB08998.1 - 1.8e-08 33.5 58.8 2.4e-07 29.8 31.4 3.3 1 1 1 3 3 3 2 Protein of unknown function (DUF3210) Ribosom_S12_S23 PF00164.20 EEB08999.2 - 1.6e-47 159.9 2.0 2e-47 159.5 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S21e PF01249.13 EEB09000.1 - 1.7e-40 136.8 0.1 1.9e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Elong_Iki1 PF10483.4 EEB09001.1 - 4.3e-47 160.7 0.5 7.1e-38 130.5 0.3 2.0 1 1 1 2 2 2 2 Elongator subunit Iki1 Ribosomal_L16 PF00252.13 EEB09002.1 - 1.5e-32 112.1 0.1 2e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CENP-K PF11802.3 EEB09003.1 - 2.1e-15 56.6 0.2 4.2e-15 55.7 0.1 1.5 1 1 0 1 1 1 1 Centromere-associated protein K Med9 PF07544.8 EEB09003.1 - 0.34 10.6 2.9 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Mnd1 PF03962.10 EEB09003.1 - 0.49 10.0 4.3 43 3.6 0.0 2.8 2 1 0 2 2 2 0 Mnd1 family Prefoldin_2 PF01920.15 EEB09003.1 - 2.1 8.1 6.3 0.86 9.4 0.1 2.7 4 0 0 4 4 4 0 Prefoldin subunit Aminotran_1_2 PF00155.16 EEB09004.2 - 2.7e-32 112.1 0.0 3.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEB09004.2 - 0.0004 18.7 0.0 0.00063 18.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2540 PF10802.3 EEB09004.2 - 0.014 15.0 0.1 0.058 13.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2540) NARP1 PF12569.3 EEB09005.2 - 1.5e-49 169.1 3.5 1.5e-49 169.1 2.4 2.7 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EEB09005.2 - 4e-14 52.0 18.1 8.9e-06 25.2 0.8 6.1 5 2 1 6 6 6 3 TPR repeat TPR_2 PF07719.12 EEB09005.2 - 4.4e-10 38.6 15.2 0.18 11.8 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEB09005.2 - 6.5e-08 32.8 13.0 1.3 9.3 0.3 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEB09005.2 - 4.8e-06 27.0 5.5 0.034 14.8 0.0 5.2 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEB09005.2 - 5e-06 26.2 0.6 0.24 11.2 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEB09005.2 - 0.00013 22.0 30.3 0.022 14.8 0.9 5.9 3 3 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEB09005.2 - 0.0026 17.6 28.5 0.045 13.6 1.6 6.7 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEB09005.2 - 0.019 14.5 12.1 7.3 6.3 0.1 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat MRP-L46 PF11788.3 EEB09005.2 - 0.082 13.5 1.3 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 TPR_8 PF13181.1 EEB09005.2 - 0.09 12.6 11.0 21 5.1 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09005.2 - 0.13 12.9 8.9 1.3e+02 3.6 0.0 6.6 5 2 4 9 9 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEB09005.2 - 6.5 6.7 11.7 12 5.8 0.1 4.8 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EEB09006.1 - 3.9e-09 36.3 5.7 0.00034 20.4 0.2 4.6 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEB09006.1 - 1.3e-08 33.9 0.3 7.1e-05 22.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEB09006.1 - 1.4e-08 34.2 7.5 0.00016 21.2 0.3 4.3 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EEB09006.1 - 6.6e-08 33.0 0.3 0.045 14.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEB09006.1 - 9.1e-08 31.4 4.6 0.00021 20.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEB09006.1 - 3e-06 26.9 0.1 0.95 9.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEB09006.1 - 3.8e-06 27.1 6.3 0.25 11.7 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09006.1 - 1.2e-05 25.5 2.5 0.037 14.6 0.0 4.7 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB09006.1 - 3.8e-05 23.1 4.4 0.0023 17.4 0.0 5.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEB09006.1 - 5.1e-05 22.7 3.3 0.017 14.8 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEB09006.1 - 0.00043 20.3 3.1 0.28 11.3 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 EEB09006.1 - 0.00091 19.1 2.7 0.44 10.4 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEB09006.1 - 0.054 13.9 3.5 1.9 9.1 0.0 4.1 4 1 0 4 4 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEB09006.1 - 0.11 12.4 2.0 4.1 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEB09006.1 - 1.8 9.2 0.0 1.8 9.2 0.0 3.4 5 0 0 5 5 2 0 Tetratricopeptide repeat Methyltransf_26 PF13659.1 EEB09007.2 - 3.5e-11 43.1 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EEB09007.2 - 7.5e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EEB09007.2 - 0.0022 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EEB09007.2 - 0.075 12.5 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 DNA methylase MTS PF05175.9 EEB09007.2 - 0.13 11.6 0.0 0.41 9.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_M22 PF00814.20 EEB09008.2 - 2e-84 283.2 0.0 2.4e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AAA_12 PF13087.1 EEB09009.2 - 1.3e-50 171.6 0.0 2.6e-50 170.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.6 EEB09009.2 - 1.6e-39 135.3 0.0 3.6e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.1 EEB09009.2 - 6.1e-38 130.7 0.0 1.1e-18 67.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EEB09009.2 - 1.1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB09009.2 - 3.6e-09 36.2 0.0 8.9e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 EEB09009.2 - 3.6e-08 33.1 0.0 5.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EEB09009.2 - 2.4e-07 30.8 0.0 4.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Helicase_RecD PF05127.9 EEB09009.2 - 4.3e-06 26.4 0.0 1.5e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Helicase SRP54 PF00448.17 EEB09009.2 - 4.3e-06 26.3 0.7 0.00055 19.4 0.1 2.7 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 EEB09009.2 - 0.00013 21.6 0.1 0.45 9.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EEB09009.2 - 0.00075 18.8 0.0 0.0017 17.6 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EEB09009.2 - 0.0084 16.1 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain DUF87 PF01935.12 EEB09009.2 - 0.012 15.4 0.3 0.03 14.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EEB09009.2 - 0.03 14.0 0.1 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEB09009.2 - 0.095 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEB09009.2 - 0.12 12.5 0.2 0.51 10.5 0.0 2.2 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EEB09009.2 - 0.17 10.6 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 EEB09009.2 - 0.28 10.6 0.1 0.74 9.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Alpha-amylase PF00128.19 EEB09010.2 - 9.6e-28 97.4 0.0 1.6e-25 90.2 0.0 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEB09010.2 - 1.1e-13 51.2 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB09010.2 - 1.7e-08 34.0 0.0 3.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EEB09010.2 - 4.4e-05 24.0 0.1 0.00021 21.8 0.1 2.1 2 0 0 2 2 2 1 Bacterial Ig-like domain Zip PF02535.17 EEB09011.1 - 1.4e-58 198.4 0.9 1.8e-58 198.0 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SIR2 PF02146.12 EEB09012.1 - 2.1e-63 213.2 0.0 3.8e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EEB09012.1 - 1.1e-05 25.0 0.1 0.0044 16.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF592) AAA_2 PF07724.9 EEB09013.2 - 1.4e-52 178.0 0.0 5.4e-51 172.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEB09013.2 - 1.2e-29 103.1 0.7 5e-16 59.0 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEB09013.2 - 8e-24 83.3 0.5 3.4e-23 81.3 0.3 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EEB09013.2 - 3.3e-17 62.1 0.2 6.5e-08 32.3 0.0 3.5 2 1 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EEB09013.2 - 9.8e-17 60.9 0.3 1.6e-10 40.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEB09013.2 - 6.9e-15 55.5 3.0 3.6e-05 23.8 0.0 5.1 3 3 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EEB09013.2 - 4.1e-14 52.8 0.3 5e-05 23.4 0.0 4.4 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEB09013.2 - 1.7e-12 47.1 0.0 6.3e-08 32.2 0.0 2.7 2 1 1 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EEB09013.2 - 1.6e-08 34.1 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EEB09013.2 - 5.4e-07 29.9 0.0 0.014 15.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEB09013.2 - 6.5e-07 30.1 11.0 0.0029 18.4 0.0 4.1 4 2 0 4 4 2 2 AAA domain Mg_chelatase PF01078.16 EEB09013.2 - 3.1e-06 26.4 0.0 0.035 13.2 0.0 3.4 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEB09013.2 - 8.5e-06 25.4 0.0 0.0057 16.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEB09013.2 - 1.5e-05 24.1 0.3 0.011 14.8 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin Arch_ATPase PF01637.13 EEB09013.2 - 3.7e-05 23.5 5.5 0.52 9.9 0.0 4.6 3 2 1 4 4 4 2 Archaeal ATPase AAA_28 PF13521.1 EEB09013.2 - 4.4e-05 23.4 0.3 1.1 9.1 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EEB09013.2 - 4.5e-05 23.1 0.5 0.42 10.3 0.0 3.8 4 0 0 4 4 4 2 Part of AAA domain AAA_33 PF13671.1 EEB09013.2 - 5.8e-05 23.0 0.0 0.037 13.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEB09013.2 - 9.3e-05 22.5 0.0 0.59 10.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EEB09013.2 - 0.00014 21.0 1.8 0.74 8.8 0.0 4.2 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus Torsin PF06309.6 EEB09013.2 - 0.00026 20.8 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Torsin T2SE PF00437.15 EEB09013.2 - 0.00054 18.9 0.0 0.004 16.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EEB09013.2 - 0.0008 18.8 0.1 1.4 8.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EEB09013.2 - 0.00082 19.6 0.8 0.89 9.8 0.0 3.7 3 1 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 EEB09013.2 - 0.00085 18.9 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EEB09013.2 - 0.0011 18.6 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EEB09013.2 - 0.0014 18.0 0.1 6.6 6.3 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EEB09013.2 - 0.0026 17.7 0.3 3.3 7.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.1 EEB09013.2 - 0.0035 17.4 0.0 6.2 6.8 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF258 PF03193.11 EEB09013.2 - 0.0098 15.0 0.0 2.8 7.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PhoH PF02562.11 EEB09013.2 - 0.014 14.6 0.0 0.73 9.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 EEB09013.2 - 0.021 14.4 0.0 1.5 8.4 0.0 2.8 3 0 0 3 3 2 0 NACHT domain ResIII PF04851.10 EEB09013.2 - 0.025 14.4 0.0 2.6 7.8 0.0 3.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PEPCK_ATP PF01293.15 EEB09013.2 - 0.032 12.7 0.0 0.22 9.9 0.0 2.2 3 0 0 3 3 2 0 Phosphoenolpyruvate carboxykinase MMR_HSR1 PF01926.18 EEB09013.2 - 0.055 13.4 0.1 2 8.4 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EEB09013.2 - 0.077 12.4 4.7 3.2 7.1 0.1 4.3 4 1 0 4 4 4 0 AAA-like domain V_ATPase_I PF01496.14 EEB09013.2 - 2.5 5.8 3.7 4.3 5.0 2.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2175 PF09943.4 EEB09013.2 - 2.9 8.0 5.8 4.8 7.2 1.4 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) APG6 PF04111.7 EEB09013.2 - 3.9 6.4 7.2 8.7 5.2 5.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Occludin_ELL PF07303.8 EEB09013.2 - 4.9 7.9 9.5 6.3 7.5 5.1 2.3 1 1 1 2 2 1 0 Occludin homology domain IncA PF04156.9 EEB09013.2 - 6.3 6.3 15.4 15 5.1 9.1 2.4 2 0 0 2 2 2 0 IncA protein Ribosomal_S13 PF00416.17 EEB09014.1 - 4.9e-40 136.2 1.7 5.8e-40 136.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEB09014.1 - 0.0019 16.8 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EEB09014.1 - 0.0054 16.7 0.6 0.034 14.1 0.1 2.3 2 1 0 2 2 2 1 Helix-hairpin-helix motif Period_C PF12114.3 EEB09014.1 - 0.037 13.6 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2746 PF10874.3 EEB09014.1 - 0.097 12.8 0.6 0.73 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) dCMP_cyt_deam_1 PF00383.17 EEB09015.1 - 3e-12 46.0 0.1 6.7e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PRK PF00485.13 EEB09015.1 - 8.1e-08 32.0 0.0 8.8e-06 25.4 0.0 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EEB09015.1 - 4.8e-07 30.1 0.1 1.1e-06 29.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEB09015.1 - 2.7e-06 28.2 0.0 6e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain APOBEC_N PF08210.6 EEB09015.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Cytidylate_kin2 PF13189.1 EEB09015.1 - 0.011 15.6 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase-like family KTI12 PF08433.5 EEB09015.1 - 0.018 14.2 0.1 0.054 12.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Bd3614-deam PF14439.1 EEB09015.1 - 0.022 14.6 0.4 0.05 13.4 0.3 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase DUF2572 PF10833.3 EEB09015.1 - 0.11 11.8 0.6 0.23 10.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) PCNA_N PF00705.13 EEB09016.2 - 1.7e-58 195.5 3.9 3.3e-58 194.7 2.7 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EEB09016.2 - 4.6e-56 188.2 0.0 9.1e-56 187.2 0.0 1.4 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EEB09016.2 - 1.2e-08 34.3 0.1 1.5e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EEB09016.2 - 0.00038 19.5 0.3 0.0029 16.6 0.0 2.0 1 1 1 2 2 2 1 Hus1-like protein TIM PF00121.13 EEB09018.1 - 6.3e-87 290.6 1.2 7.2e-87 290.4 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF2462 PF09495.5 EEB09021.1 - 1.2e-14 54.7 12.3 1.5e-14 54.4 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) EMP24_GP25L PF01105.19 EEB09022.1 - 6.5e-45 153.0 0.6 7.5e-45 152.8 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2077 PF09850.4 EEB09022.1 - 0.0001 21.7 0.1 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) DDE_Tnp_IS1595 PF12762.2 EEB09022.1 - 0.024 14.4 0.5 0.042 13.6 0.3 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF3753 PF12575.3 EEB09022.1 - 2.2 8.1 4.2 0.45 10.3 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) PIN_4 PF13638.1 EEB09024.2 - 3.6e-31 108.0 0.0 6.2e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain XLF PF09302.6 EEB09025.1 - 4.4e-12 46.0 0.1 5.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) XRCC4 PF06632.7 EEB09025.1 - 0.0058 15.5 0.1 0.033 13.0 0.0 1.9 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SH3_9 PF14604.1 EEB09026.1 - 4.8e-10 38.8 0.3 1.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EEB09026.1 - 1.3e-09 37.2 0.1 3.6e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEB09026.1 - 2.9e-06 26.6 0.0 6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3073 PF11273.3 EEB09026.1 - 0.05 14.1 0.2 0.094 13.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3073) Lysozyme_like PF13702.1 EEB09026.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysozyme-like CGI-121 PF08617.5 EEB09027.1 - 4.8e-41 140.1 0.5 6.6e-41 139.6 0.3 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 THOC7 PF05615.8 EEB09028.1 - 1.9e-13 50.8 24.4 6.1e-13 49.2 11.2 2.6 1 1 1 2 2 2 1 Tho complex subunit 7 AAA_13 PF13166.1 EEB09028.1 - 0.00023 19.7 14.2 0.00027 19.5 9.9 1.0 1 0 0 1 1 1 1 AAA domain DUF848 PF05852.6 EEB09028.1 - 0.00082 19.2 2.8 0.00082 19.2 2.0 2.2 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) KxDL PF10241.4 EEB09028.1 - 0.0031 17.3 5.4 0.029 14.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein GDI PF00996.13 EEB09028.1 - 0.0054 15.0 1.3 0.015 13.6 0.0 2.0 1 1 0 2 2 2 1 GDP dissociation inhibitor DUF342 PF03961.8 EEB09028.1 - 0.007 14.8 9.3 0.0088 14.5 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Striatin PF08232.7 EEB09028.1 - 0.0071 16.6 13.4 0.01 16.1 9.3 1.3 1 0 0 1 1 1 1 Striatin family Phage_GPA PF05840.8 EEB09028.1 - 0.01 14.5 4.3 0.014 14.1 3.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) TORC_N PF12884.2 EEB09028.1 - 0.016 15.7 6.4 3.4 8.2 0.0 2.7 2 1 0 2 2 2 0 Transducer of regulated CREB activity, N terminus DUF2278 PF10042.4 EEB09028.1 - 0.043 13.5 2.1 0.052 13.2 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) OmpH PF03938.9 EEB09028.1 - 0.11 12.4 12.1 0.17 11.8 8.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipoprotein_6 PF01441.14 EEB09028.1 - 0.12 12.2 5.5 0.15 11.8 3.8 1.4 1 0 0 1 1 1 0 Lipoprotein Mnd1 PF03962.10 EEB09028.1 - 0.17 11.5 17.8 0.33 10.5 12.4 1.5 1 1 0 1 1 1 0 Mnd1 family DUF87 PF01935.12 EEB09028.1 - 0.2 11.4 7.1 0.25 11.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Prominin PF05478.6 EEB09028.1 - 0.24 8.9 12.6 1.7 6.1 8.6 1.8 1 1 0 1 1 1 0 Prominin HsdM_N PF12161.3 EEB09028.1 - 0.24 11.8 4.5 0.4 11.0 3.1 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain PRANC PF09372.5 EEB09028.1 - 0.29 11.1 2.5 1.6 8.7 0.6 2.5 1 1 1 2 2 2 0 PRANC domain GrpE PF01025.14 EEB09028.1 - 0.29 10.6 18.9 0.061 12.8 1.6 2.3 1 1 1 2 2 2 0 GrpE Laminin_I PF06008.9 EEB09028.1 - 0.31 10.2 14.8 0.31 10.3 1.5 2.0 1 1 1 2 2 2 0 Laminin Domain I DUF948 PF06103.6 EEB09028.1 - 0.56 10.0 7.5 2.8 7.8 1.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CAMP_factor PF07373.6 EEB09028.1 - 0.58 9.6 7.8 0.14 11.6 1.3 2.0 1 1 1 2 2 2 0 CAMP factor (Cfa) Tho2 PF11262.3 EEB09028.1 - 0.71 8.8 13.9 0.074 12.0 4.0 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 EEB09028.1 - 0.71 9.4 23.3 24 4.4 16.2 2.2 1 1 0 1 1 1 0 IncA protein UBN2_3 PF14244.1 EEB09028.1 - 0.77 9.3 8.6 0.3 10.6 3.0 2.0 1 1 0 2 2 2 0 gag-polypeptide of LTR copia-type G6PD_N PF00479.17 EEB09028.1 - 0.89 9.7 7.3 0.75 9.9 3.0 2.1 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF745 PF05335.8 EEB09028.1 - 0.89 9.0 9.7 1.4 8.3 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Prefoldin PF02996.12 EEB09028.1 - 0.89 9.2 14.0 2 8.0 1.1 2.6 2 1 0 2 2 2 0 Prefoldin subunit AATF-Che1 PF13339.1 EEB09028.1 - 0.97 9.5 12.7 3.7 7.7 2.7 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Syntaxin_2 PF14523.1 EEB09028.1 - 1 9.4 11.3 8.3 6.5 5.6 2.6 1 1 1 2 2 2 0 Syntaxin-like protein APG6 PF04111.7 EEB09028.1 - 1 8.3 23.9 6 5.8 14.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 FlgN PF05130.7 EEB09028.1 - 1.1 9.5 11.1 1.8 8.8 7.7 1.4 1 1 0 1 1 1 0 FlgN protein Lebercilin PF15619.1 EEB09028.1 - 1.2 8.4 19.8 2 7.8 12.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IFT46_B_C PF12317.3 EEB09028.1 - 1.4 8.2 10.8 2.1 7.6 2.1 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Snapin_Pallidin PF14712.1 EEB09028.1 - 1.6 9.1 10.4 6.8 7.0 4.8 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Sulfatase_C PF14707.1 EEB09028.1 - 1.8 8.8 6.1 17 5.7 0.2 2.5 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase GP41 PF00517.12 EEB09028.1 - 2.2 7.7 8.3 4.5 6.7 0.3 2.4 1 1 0 2 2 2 0 Retroviral envelope protein DUF4208 PF13907.1 EEB09028.1 - 2.7 8.2 9.2 7 6.9 5.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF4355 PF14265.1 EEB09028.1 - 3.4 7.6 20.1 3.8 7.4 13.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1759 PF03564.10 EEB09028.1 - 4.9 6.9 9.1 16 5.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Rotamase PF00639.16 EEB09028.1 - 6.9 7.4 8.3 27 5.5 4.0 2.5 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF4367 PF14285.1 EEB09028.1 - 6.9 5.9 10.4 9.6 5.4 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) FlxA PF14282.1 EEB09028.1 - 7.2 6.6 18.3 2.6 8.0 4.6 2.4 1 1 1 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.7 EEB09028.1 - 8.6 6.1 21.2 2.7 7.7 11.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FTCD_C PF04961.7 EEB09028.1 - 8.7 5.7 8.5 6.9 6.0 0.2 2.5 1 1 2 3 3 3 0 Formiminotransferase-cyclodeaminase LON PF02190.11 EEB09028.1 - 8.8 5.9 10.8 9.4 5.8 5.8 1.9 1 1 1 2 2 2 0 ATP-dependent protease La (LON) domain Med21 PF11221.3 EEB09028.1 - 8.9 6.2 14.8 1.8 8.5 1.3 2.5 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Med9 PF07544.8 EEB09028.1 - 9.9 5.9 17.1 16 5.2 2.5 3.6 4 0 0 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA PF00004.24 EEB09029.2 - 4.6e-38 130.4 0.0 8.4e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEB09029.2 - 1.7e-09 37.9 0.8 0.00025 21.2 0.0 3.4 1 1 2 3 3 3 2 AAA domain AAA_14 PF13173.1 EEB09029.2 - 6.8e-07 29.2 0.0 1.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEB09029.2 - 1e-06 29.5 0.1 2.6e-06 28.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEB09029.2 - 1.5e-06 28.3 6.5 0.00069 19.6 0.0 2.9 3 1 1 4 4 2 2 AAA ATPase domain RuvB_N PF05496.7 EEB09029.2 - 4.5e-06 25.8 0.0 9e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEB09029.2 - 1.6e-05 24.6 0.6 0.00021 21.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEB09029.2 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEB09029.2 - 0.00012 21.4 3.2 0.039 13.3 0.2 2.8 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EEB09029.2 - 0.00014 21.3 0.1 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEB09029.2 - 0.00041 19.5 1.8 0.00069 18.8 0.2 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEB09029.2 - 0.00047 19.2 0.1 0.0017 17.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.1 EEB09029.2 - 0.00048 20.1 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EEB09029.2 - 0.00062 19.9 0.0 0.0014 18.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 EEB09029.2 - 0.00067 19.3 1.0 0.017 14.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 EEB09029.2 - 0.0013 18.3 0.1 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEB09029.2 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EEB09029.2 - 0.0017 17.1 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EEB09029.2 - 0.0018 17.9 0.1 0.19 11.3 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EEB09029.2 - 0.002 18.1 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EEB09029.2 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Sigma54_activat PF00158.21 EEB09029.2 - 0.0025 17.3 0.1 0.011 15.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EEB09029.2 - 0.0047 17.2 0.1 0.0081 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EEB09029.2 - 0.0074 15.4 0.1 1.3 8.0 0.0 2.4 1 1 1 2 2 2 1 KaiC DEAD PF00270.24 EEB09029.2 - 0.0079 15.7 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SKI PF01202.17 EEB09029.2 - 0.015 15.1 0.1 0.068 13.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_3 PF07726.6 EEB09029.2 - 0.019 14.5 0.0 0.047 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEB09029.2 - 0.023 14.4 0.2 0.079 12.7 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_10 PF12846.2 EEB09029.2 - 0.03 13.7 2.2 0.65 9.3 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain TIP49 PF06068.8 EEB09029.2 - 0.036 12.7 0.1 0.076 11.7 0.0 1.5 1 1 1 2 2 2 0 TIP49 C-terminus DUF815 PF05673.8 EEB09029.2 - 0.039 12.8 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EEB09029.2 - 0.043 13.3 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EEB09029.2 - 0.044 14.0 0.0 0.096 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 EEB09029.2 - 0.047 13.6 0.5 9.4 6.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EEB09029.2 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.6 EEB09029.2 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain Guanylate_kin PF00625.16 EEB09029.2 - 0.081 12.3 0.0 0.81 9.1 0.0 2.4 2 1 1 3 3 3 0 Guanylate kinase NB-ARC PF00931.17 EEB09029.2 - 0.085 11.6 0.0 0.24 10.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 EEB09029.2 - 0.089 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EEB09029.2 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EEB09029.2 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Ribosomal_S17e PF00833.13 EEB09030.2 - 3.2e-61 204.4 1.1 3.7e-61 204.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 AIG2 PF06094.7 EEB09030.2 - 0.022 15.2 0.2 0.029 14.8 0.1 1.3 1 0 0 1 1 1 0 AIG2-like family ZZ PF00569.12 EEB09031.1 - 2e-12 46.4 6.4 3.5e-12 45.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EEB09031.1 - 2.2e-10 40.5 0.0 6.5e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EEB09031.1 - 3.8e-10 39.6 0.0 1.5e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.6 EEB09031.1 - 0.024 14.3 1.9 0.055 13.1 1.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 EEB09031.1 - 0.78 9.5 6.4 1.7 8.4 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain C1_3 PF07649.7 EEB09031.1 - 1.3 9.1 10.5 2.2 8.3 7.3 1.4 1 0 0 1 1 1 0 C1-like domain Pkinase PF00069.20 EEB09032.1 - 2.3e-68 230.1 0.0 3.3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09032.1 - 2.1e-29 102.3 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEB09032.1 - 1.4e-07 31.8 1.2 4.1e-07 30.4 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB09032.1 - 0.00052 19.0 0.0 0.0014 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEB09032.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L50 PF10501.4 EEB09033.1 - 9.3e-07 28.8 0.0 1.9e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal subunit 39S zf-Tim10_DDP PF02953.10 EEB09034.1 - 6.9e-20 70.1 2.2 8.8e-20 69.7 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Apc4 PF12896.2 EEB09034.1 - 0.054 12.7 0.6 0.086 12.1 0.2 1.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Phasin_2 PF09361.5 EEB09034.1 - 0.08 12.9 0.2 3.8 7.6 0.1 2.0 1 1 1 2 2 2 0 Phasin protein MCM PF00493.18 EEB09036.1 - 1.6e-136 454.4 0.4 2.1e-136 454.1 0.3 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEB09036.1 - 8.7e-25 87.5 1.9 3.3e-24 85.6 0.1 2.9 4 0 0 4 4 4 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEB09036.1 - 4.1e-06 26.1 0.0 0.00036 19.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEB09036.1 - 9.8e-06 25.3 0.0 2.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEB09036.1 - 0.00013 21.6 0.0 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEB09036.1 - 0.0088 15.5 0.3 3.6 7.0 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 EEB09036.1 - 0.18 11.7 0.4 0.36 10.8 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Proteasom_Rpn13 PF04683.8 EEB09037.1 - 1.9e-29 101.5 0.0 3.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SNF5 PF04855.7 EEB09039.2 - 7.9e-58 195.8 0.3 5.7e-56 189.7 0.2 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EEB09039.2 - 5.6e-10 38.3 5.4 5.6e-10 38.3 3.7 2.7 3 0 0 3 3 3 1 GATA zinc finger LUC7 PF03194.10 EEB09040.1 - 3.9e-83 278.8 8.7 4.9e-83 278.5 6.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus FliT PF05400.8 EEB09040.1 - 0.65 10.4 9.7 0.25 11.7 0.9 2.9 2 1 0 2 2 2 0 Flagellar protein FliT DUF4200 PF13863.1 EEB09040.1 - 1 9.3 14.2 0.12 12.3 1.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) UCH PF00443.24 EEB09041.1 - 8.1e-77 257.9 1.8 1.3e-76 257.2 1.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB09041.1 - 3e-25 89.2 1.6 2.8e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EEB09041.1 - 4.8e-10 39.7 0.0 1.4e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 DUSP domain L31 PF09784.4 EEB09042.1 - 2.2e-41 140.0 0.5 2.5e-41 139.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cyt-b5 PF00173.23 EEB09043.1 - 4.3e-25 87.3 0.1 5.9e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tim17 PF02466.14 EEB09044.1 - 3.1e-28 98.3 6.5 3.7e-28 98.1 4.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PX PF00787.19 EEB09045.1 - 1.9e-19 69.5 0.3 7.6e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 PX domain DUF2009 PF09418.5 EEB09046.2 - 5.1e-193 642.0 0.8 5.9e-193 641.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PXA PF02194.10 EEB09047.1 - 2.9e-33 114.9 0.2 2.9e-33 114.9 0.1 1.9 2 0 0 2 2 2 1 PXA domain PX PF00787.19 EEB09047.1 - 1.5e-20 73.0 1.8 3.4e-19 68.6 0.1 3.4 3 1 1 4 4 4 1 PX domain RGS PF00615.14 EEB09047.1 - 3.8e-20 72.1 0.6 1.2e-19 70.5 0.1 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.7 EEB09047.1 - 5.5e-05 23.2 0.1 0.00036 20.6 0.0 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal Hemerythrin PF01814.18 EEB09047.1 - 0.27 11.3 2.3 0.44 10.7 0.1 2.5 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DIM1 PF02966.11 EEB09048.1 - 1.2e-70 235.2 0.3 1.3e-70 235.0 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EEB09048.1 - 0.0049 16.5 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Polyketide_cyc PF03364.15 EEB09049.1 - 1.7e-24 86.2 0.0 2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EEB09049.1 - 0.00017 21.7 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_transf_22 PF03901.12 EEB09050.1 - 7.2e-99 331.6 33.1 8.4e-99 331.4 22.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EEB09050.1 - 1.8e-08 34.4 14.7 1.8e-08 34.4 10.2 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 EEB09051.1 - 2.2e-90 293.6 23.2 1.4e-10 40.6 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 EEB09051.1 - 1.5e-44 151.0 0.8 2.8e-44 150.1 0.6 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EEB09051.1 - 7.4e-08 30.9 9.4 0.35 8.9 0.0 6.2 3 3 4 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB09051.1 - 8.3e-07 28.0 2.2 0.51 9.0 0.0 5.7 2 2 3 6 6 6 3 Nup133 N terminal like Frag1 PF10277.4 EEB09052.1 - 2.7e-30 105.4 19.6 3.3e-30 105.1 13.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4149 PF13664.1 EEB09052.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF4199 PF13858.1 EEB09052.1 - 0.89 9.4 7.5 1.6 8.6 2.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) DUF3812 PF12757.2 EEB09053.2 - 5.3e-23 81.3 10.2 5.3e-23 81.3 7.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) DnaJ PF00226.26 EEB09054.1 - 1.5e-21 75.9 0.1 5.7e-21 74.0 0.4 1.7 2 0 0 2 2 2 1 DnaJ domain DUF456 PF04306.8 EEB09054.1 - 0.00029 20.8 0.1 0.00044 20.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EEB09054.1 - 0.035 13.7 2.0 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Metal_resist PF13801.1 EEB09054.1 - 0.84 9.6 0.0 0.84 9.6 0.0 2.7 3 1 0 3 3 3 0 Heavy-metal resistance Bacteriocin_IIc PF10439.4 EEB09054.1 - 4.1 7.5 8.0 0.34 11.0 1.2 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Proteasome PF00227.21 EEB09055.1 - 1.6e-43 148.2 0.0 1.8e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 EEB09056.1 - 5.4e-46 156.1 0.0 1.8e-43 147.9 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09056.1 - 8.1e-26 89.7 0.1 1.7e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EEB09056.1 - 0.0033 17.7 1.1 0.013 15.8 0.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) Peripla_BP_1 PF00532.16 EEB09056.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PRAI PF00697.17 EEB09056.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ResIII PF04851.10 EEB09056.1 - 0.058 13.2 0.7 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HEAT_PBS PF03130.11 EEB09056.1 - 0.086 13.3 0.2 0.44 11.1 0.0 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat CTP_transf_1 PF01148.15 EEB09057.1 - 4.9e-10 39.5 11.3 4.9e-10 39.5 7.8 3.0 1 1 2 3 3 3 1 Cytidylyltransferase family MatE PF01554.13 EEB09057.1 - 0.00042 19.9 0.6 0.00042 19.9 0.4 2.2 2 0 0 2 2 2 1 MatE Pkinase PF00069.20 EEB09058.1 - 2e-57 194.3 0.0 3.1e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 EEB09058.1 - 8.5e-43 146.2 1.2 1.4e-42 145.5 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 EEB09058.1 - 1.2e-40 139.1 0.0 1.7e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09058.1 - 0.0072 15.3 0.0 2.9 6.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEB09058.1 - 0.13 11.9 0.0 0.46 10.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Thg1C PF14413.1 EEB09059.1 - 6e-51 171.2 0.4 9e-51 170.6 0.3 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EEB09059.1 - 1.2e-45 154.4 0.1 1.9e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 EEB09060.1 - 2.3e-10 39.9 2.2 0.02 14.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEB09060.1 - 0.018 13.3 0.0 0.22 9.7 0.0 2.3 1 1 2 3 3 3 0 Cytochrome D1 heme domain TAP42 PF04177.7 EEB09061.1 - 2e-77 260.4 21.6 3.6e-77 259.5 15.0 1.4 1 1 0 1 1 1 1 TAP42-like family Mis14 PF08641.7 EEB09061.1 - 1.1 9.3 9.0 0.14 12.2 0.6 2.9 2 1 0 2 2 2 0 Kinetochore protein Mis14 like Glyco_transf_5 PF08323.6 EEB09062.1 - 5e-14 52.3 0.3 9.8e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEB09062.1 - 9.4e-10 38.1 0.0 1.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEB09062.1 - 0.076 13.1 0.2 5 7.2 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF3395 PF11875.3 EEB09063.1 - 5.3e-21 74.8 1.3 1.4e-20 73.4 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EEB09063.1 - 3.4e-17 61.9 2.8 7.9e-17 60.7 2.0 1.7 1 0 0 1 1 1 1 DnaJ domain Hydrolase_6 PF13344.1 EEB09063.1 - 0.0093 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Alpha-amylase PF00128.19 EEB09064.1 - 2.2e-59 201.4 2.6 3e-59 200.9 1.8 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEB09064.1 - 3.4e-13 49.4 0.5 3.4e-13 49.4 0.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) LNP1 PF15419.1 EEB09065.1 - 0.01 15.9 1.4 0.019 15.0 1.0 1.4 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Complex1_LYR PF05347.10 EEB09066.2 - 1.8e-08 34.0 1.3 2.8e-08 33.4 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEB09066.2 - 9.4e-08 32.1 0.6 2.1e-07 31.0 0.1 2.0 2 1 0 2 2 2 1 Complex1_LYR-like Sugar_tr PF00083.19 EEB09067.1 - 1.4e-38 132.6 18.3 3.3e-23 82.0 0.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEB09067.1 - 6.1e-20 71.2 25.4 8.1e-13 47.8 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP_assoc PF03828.14 EEB09067.1 - 0.8 9.6 3.9 0.26 11.2 0.3 2.1 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF89 PF01937.14 EEB09068.1 - 4.9e-119 397.2 0.0 5.5e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF883 PF05957.8 EEB09069.1 - 0.02 15.2 3.6 0.02 15.2 2.5 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 EEB09069.1 - 0.55 10.0 6.3 0.76 9.5 4.4 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2229 PF09989.4 EEB09069.1 - 0.77 9.1 3.1 1.3 8.4 2.1 1.4 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) LEA_4 PF02987.11 EEB09069.1 - 1.3 8.9 8.3 1.4 8.8 1.1 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein Dak2 PF02734.12 EEB09069.1 - 1.7 8.2 6.2 5.9 6.5 4.3 1.7 1 1 0 1 1 1 0 DAK2 domain MRP-L20 PF12824.2 EEB09070.2 - 4.8e-17 62.4 0.1 6.4e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EEB09070.2 - 0.0015 18.3 0.4 0.0033 17.3 0.3 1.4 1 1 1 2 2 2 1 Neugrin Metal_resist PF13801.1 EEB09070.2 - 0.014 15.4 1.6 0.02 14.8 1.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance HDV_ag PF01517.13 EEB09070.2 - 0.041 13.5 0.1 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Ten1 PF12658.2 EEB09071.1 - 2.6e-17 62.7 0.1 3e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ctr PF04145.10 EEB09072.1 - 3.9e-35 121.0 4.8 3.9e-35 121.0 3.3 1.9 2 0 0 2 2 2 1 Ctr copper transporter family Macoilin PF09726.4 EEB09072.1 - 1.2 7.3 5.0 1.6 6.9 3.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Lung_7-TM_R PF06814.8 EEB09073.1 - 2.3e-06 26.7 3.3 4.2e-06 25.9 2.3 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor RWD PF05773.17 EEB09074.1 - 3.2e-18 65.6 1.8 6.1e-18 64.7 1.2 1.5 1 0 0 1 1 1 1 RWD domain DUF445 PF04286.7 EEB09074.1 - 0.00025 20.7 4.4 0.00029 20.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1003 PF06210.6 EEB09074.1 - 0.22 11.4 1.8 0.3 11.0 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) GATA PF00320.22 EEB09075.2 - 2.4e-28 97.1 19.7 2.8e-14 52.1 4.7 3.2 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEB09075.2 - 3.5e-05 23.0 1.6 0.082 12.2 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding NMD3 PF04981.8 EEB09075.2 - 0.0093 15.0 2.3 1 8.4 0.2 2.1 2 0 0 2 2 2 2 NMD3 family FYVE PF01363.16 EEB09075.2 - 0.043 13.7 5.3 0.088 12.7 3.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 EEB09075.2 - 0.19 11.5 9.7 10 6.0 6.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EEB09075.2 - 0.35 10.5 5.9 1.6 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.1 EEB09075.2 - 4.7 7.6 7.0 11 6.4 3.9 2.1 1 1 1 2 2 2 0 Cytochrome c3 Ipi1_N PF12333.3 EEB09077.2 - 3.5e-27 94.3 0.3 1.4e-26 92.4 0.1 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CP2 PF04516.10 EEB09079.1 - 0.019 14.0 0.3 0.029 13.4 0.2 1.3 1 0 0 1 1 1 0 CP2 transcription factor PMD PF10536.4 EEB09079.1 - 0.049 12.6 0.7 0.064 12.2 0.5 1.2 1 0 0 1 1 1 0 Plant mobile domain Apis_Csd PF11671.3 EEB09079.1 - 0.094 12.5 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein ECM11 PF15463.1 EEB09079.1 - 5.2 7.3 7.5 2.9 8.1 0.0 3.1 3 1 0 3 3 3 0 Extracellular mutant protein 11 FTA4 PF13093.1 EEB09080.1 - 2.8e-40 138.0 18.7 4.4e-40 137.3 13.0 1.3 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 YqfD PF06898.6 EEB09080.1 - 0.031 12.9 0.4 0.043 12.5 0.3 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD NPV_P10 PF05531.7 EEB09080.1 - 1.2 9.3 6.7 1.8 8.8 3.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_S19 PF00203.16 EEB09081.1 - 1.8e-31 107.5 0.1 3.1e-31 106.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 SPT2 PF08243.6 EEB09082.1 - 2.5e-26 92.2 6.9 2.5e-26 92.2 4.8 3.3 2 1 1 3 3 3 1 SPT2 chromatin protein DUF2924 PF11149.3 EEB09082.1 - 0.25 11.3 10.4 0.59 10.1 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) V_ATPase_I PF01496.14 EEB09082.1 - 2.5 5.8 4.0 3.5 5.3 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EEB09082.1 - 9.6 4.4 11.3 15 3.8 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) E1-E2_ATPase PF00122.15 EEB09083.2 - 1.4e-61 207.4 5.4 3.2e-61 206.3 3.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEB09083.2 - 2.1e-24 87.1 0.0 3.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB09083.2 - 4.4e-14 53.0 0.0 2.2e-12 47.5 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEB09083.2 - 1.1e-10 40.7 0.0 2.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEB09083.2 - 0.0018 17.9 0.1 0.0041 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB09083.2 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Spc7 PF08317.6 EEB09084.1 - 1.4e-65 221.1 5.6 1.4e-65 221.1 3.9 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EEB09084.1 - 1.2e-18 66.4 0.5 3.4e-18 65.0 0.4 1.8 1 0 0 1 1 1 1 Spc7_C2 Cation_efflux PF01545.16 EEB09085.1 - 2.1e-47 161.5 2.2 2.7e-47 161.2 1.5 1.1 1 0 0 1 1 1 1 Cation efflux family RNA_pol_Rpb6 PF01192.17 EEB09086.1 - 4.5e-24 83.9 0.1 6.4e-24 83.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Metallophos PF00149.23 EEB09087.1 - 4.9e-12 45.6 0.0 1.5e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEB09087.1 - 2.9e-08 33.7 0.0 5.3e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transaldolase PF00923.14 EEB09088.1 - 3.1e-96 321.8 1.0 3.5e-96 321.7 0.7 1.0 1 0 0 1 1 1 1 Transaldolase HAD_2 PF13419.1 EEB09089.1 - 4.2e-18 66.1 0.0 5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB09089.1 - 6.9e-09 36.4 0.0 2e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB09089.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 EEB09089.1 - 0.0015 18.1 0.0 0.0051 16.3 0.0 1.9 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.1 EEB09089.1 - 0.013 15.3 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.16 EEB09090.1 - 2.1e-28 99.5 0.1 7.8e-28 97.7 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EEB09090.1 - 6.7e-26 90.1 0.0 2e-25 88.6 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EEB09090.1 - 3.2e-13 49.8 0.0 5.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EEB09090.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain WD40 PF00400.27 EEB09091.1 - 1.4e-13 50.1 1.8 8.4e-07 28.6 0.4 6.5 6 1 0 6 6 6 2 WD domain, G-beta repeat IKI3 PF04762.7 EEB09091.1 - 0.036 11.9 0.0 0.58 7.9 0.0 2.2 1 1 2 3 3 3 0 IKI3 family Nbas_N PF15492.1 EEB09091.1 - 0.099 11.7 0.0 0.76 8.8 0.0 2.0 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.20 EEB09092.2 - 6.5e-56 189.3 0.0 1.5e-55 188.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09092.2 - 1.6e-18 66.7 0.0 2.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB09092.2 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FAD_binding_1 PF00667.15 EEB09094.1 - 6.4e-65 218.6 0.1 8.9e-65 218.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEB09094.1 - 2.8e-33 114.9 1.7 2.9e-33 114.8 0.4 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EEB09094.1 - 4.9e-21 75.3 0.1 1.6e-20 73.6 0.1 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEB09094.1 - 0.1 12.5 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EEB09095.1 - 1.8e-25 88.3 0.0 1.8e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09095.1 - 8.9e-17 60.8 0.0 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09095.1 - 0.00076 19.2 0.2 0.064 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1A PF12253.3 EEB09096.1 - 3.3e-18 65.5 9.0 3.3e-18 65.5 6.2 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EEB09096.1 - 3e-10 39.8 39.2 3e-10 39.8 27.2 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CUE PF02845.11 EEB09096.1 - 0.0064 15.9 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF3492 PF11997.3 EEB09096.1 - 1.8 8.0 8.2 3.9 6.9 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF1546 PF07571.8 EEB09098.1 - 1.8e-34 117.7 0.0 3.9e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EEB09098.1 - 1.1e-29 102.1 0.1 2.3e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EEB09098.1 - 4.3e-05 23.5 0.2 0.00059 19.9 0.0 2.5 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEB09098.1 - 0.00072 19.5 0.1 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT PF02985.17 EEB09098.1 - 0.0038 17.1 2.1 2.1 8.6 0.1 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EEB09098.1 - 0.013 15.8 0.0 5.4 7.3 0.0 3.3 2 1 0 2 2 2 0 HEAT repeats Vps5 PF09325.5 EEB09099.1 - 4.3e-61 206.1 12.6 4.3e-61 206.1 8.8 1.8 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EEB09099.1 - 2.3e-22 78.9 0.4 1.4e-21 76.4 0.0 2.4 2 1 0 2 2 2 1 PX domain Phage_Gp23 PF10669.4 EEB09099.1 - 7.4 6.7 7.6 2.1 8.4 1.0 2.8 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) FGGY_N PF00370.16 EEB09100.1 - 2e-26 92.8 0.0 7.1e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EEB09100.1 - 9.2e-23 80.8 0.0 1.9e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ABC2_membrane PF01061.19 EEB09101.1 - 5.7e-83 277.2 53.2 6.6e-44 149.5 14.2 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EEB09101.1 - 2.6e-35 120.1 9.6 4.8e-31 106.4 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EEB09101.1 - 6.4e-32 110.7 0.0 2.1e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EEB09101.1 - 4.3e-11 42.7 0.2 1.1e-10 41.5 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EEB09101.1 - 2.5e-06 26.7 0.0 9.9e-05 21.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEB09101.1 - 4.3e-06 26.2 0.0 0.00036 19.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EEB09101.1 - 8.2e-05 22.6 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EEB09101.1 - 8.3e-05 22.0 0.1 0.04 13.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EEB09101.1 - 0.0011 18.1 20.0 0.0011 18.1 13.8 4.2 2 2 1 3 3 3 1 ABC-2 family transporter protein UPF0079 PF02367.12 EEB09101.1 - 0.0013 18.3 0.2 0.14 11.8 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EEB09101.1 - 0.0014 18.1 1.1 0.0032 16.9 0.2 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEB09101.1 - 0.0015 19.3 0.3 0.074 13.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEB09101.1 - 0.0058 15.7 0.1 4.1 6.4 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 EEB09101.1 - 0.0059 16.7 0.0 0.079 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEB09101.1 - 0.006 16.2 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EEB09101.1 - 0.007 16.3 0.3 0.52 10.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EEB09101.1 - 0.0082 15.8 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EEB09101.1 - 0.014 15.3 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EEB09101.1 - 0.015 15.4 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EEB09101.1 - 0.023 14.5 0.0 1.4 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EEB09101.1 - 0.025 14.0 0.2 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EEB09101.1 - 0.045 14.0 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEB09101.1 - 0.048 13.1 0.0 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EEB09101.1 - 0.091 12.1 0.1 3.2 7.1 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 EEB09101.1 - 0.099 12.2 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEB09101.1 - 0.11 12.8 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 EEB09101.1 - 0.28 9.8 0.1 1.6 7.4 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ABC_ATPase PF09818.4 EEB09101.1 - 0.33 9.4 0.1 0.64 8.5 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Pkinase PF00069.20 EEB09102.1 - 4.7e-51 173.4 0.0 6.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09102.1 - 7.1e-35 120.3 0.0 9.8e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09102.1 - 0.0048 15.8 0.0 0.011 14.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EEB09102.1 - 0.15 10.8 0.1 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S18 PF01084.15 EEB09103.2 - 3.3e-18 65.2 0.8 4.5e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 Phos_pyr_kin PF08543.7 EEB09104.2 - 1.6e-62 210.9 0.0 2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 EEB09104.2 - 6.4e-05 22.2 0.1 0.00027 20.1 0.0 1.9 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family eRF1_1 PF03463.10 EEB09105.1 - 1.1e-42 144.7 0.5 4e-42 142.9 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 EEB09105.1 - 1e-30 106.8 0.1 1.5e-30 106.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEB09105.1 - 2.5e-23 82.5 0.0 5.2e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 Ran_BP1 PF00638.13 EEB09106.1 - 8.6e-21 74.2 0.2 2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EEB09106.1 - 3.6e-17 62.4 1.9 3.6e-17 62.4 1.3 4.3 4 2 1 5 5 5 1 NUP50 (Nucleoporin 50 kDa) IncA PF04156.9 EEB09106.1 - 0.067 12.7 0.3 0.09 12.3 0.2 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_1 PF00133.17 EEB09107.1 - 3e-148 494.4 0.0 4.6e-148 493.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEB09107.1 - 8.5e-21 74.0 0.3 8.6e-13 47.6 0.0 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEB09107.1 - 1.2e-17 64.0 1.0 2.4e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EEB09107.1 - 0.0032 17.0 3.9 0.0065 16.0 2.7 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EEB09107.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DUF2414 PF10309.4 EEB09108.1 - 2.9e-05 23.6 0.1 4.1e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) PB1 PF00564.19 EEB09108.1 - 0.0071 15.9 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 PB1 domain RNA_bind PF08675.6 EEB09108.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain WD40 PF00400.27 EEB09109.1 - 1.8e-28 97.3 15.0 1.3e-05 24.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EEB09109.1 - 3.4e-12 46.4 0.9 7e-05 22.6 0.0 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EEB09109.1 - 6.8e-07 27.5 1.2 0.0047 14.8 0.1 3.0 3 0 0 3 3 3 2 IKI3 family Coatomer_WDAD PF04053.9 EEB09109.1 - 0.00016 20.6 0.0 0.016 14.0 0.0 2.3 2 1 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 EEB09109.1 - 0.00022 19.6 0.0 0.087 11.0 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Pkinase PF00069.20 EEB09110.1 - 1.3e-74 250.6 0.1 1.7e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09110.1 - 4.8e-40 137.2 0.1 6.7e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEB09110.1 - 4.1e-15 55.6 0.4 8.6e-15 54.6 0.3 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EEB09110.1 - 1.7e-14 53.5 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEB09110.1 - 4.7e-06 26.0 0.4 1.1e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EEB09110.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB09110.1 - 0.022 14.5 0.0 0.22 11.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CoaE PF01121.15 EEB09111.1 - 3.3e-59 199.3 0.0 3.8e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EEB09111.1 - 5.6e-08 33.6 0.0 9.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB09111.1 - 1.4e-05 25.4 0.2 7e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEB09111.1 - 0.0086 15.9 0.0 0.034 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EEB09111.1 - 0.031 14.1 0.1 0.24 11.2 0.1 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.17 EEB09111.1 - 0.032 14.0 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.7 EEB09111.1 - 0.052 12.6 0.2 4.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EEB09111.1 - 0.12 12.2 0.1 0.93 9.2 0.0 2.0 2 0 0 2 2 2 0 Dynamin family APG9 PF04109.11 EEB09111.1 - 0.76 8.6 4.2 3 6.6 0.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg9 Npa1 PF11707.3 EEB09112.2 - 1.9e-55 188.1 3.1 1.9e-55 188.1 2.1 2.7 3 1 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Tra_M PF05261.6 EEB09112.2 - 0.011 15.7 0.7 3.9 7.5 0.1 3.3 2 0 0 2 2 2 0 TraM protein, DNA-binding UMP1 PF05348.6 EEB09113.1 - 7.2e-28 97.1 0.0 7.6e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 CDV3 PF15359.1 EEB09114.1 - 0.068 13.2 0.2 0.068 13.2 0.1 3.2 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 DDHD PF02862.12 EEB09115.1 - 1.1e-37 130.0 0.5 1.5e-35 123.0 0.4 2.2 1 1 0 1 1 1 1 DDHD domain DUF2305 PF10230.4 EEB09115.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EEB09115.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family cobW PF02492.14 EEB09115.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF4506 PF14958.1 EEB09115.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) XAP5 PF04921.9 EEB09116.1 - 4.8e-52 176.8 7.3 6.4e-52 176.4 5.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator Calici_MSP PF05752.6 EEB09116.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein Rab5ip PF07019.7 EEB09117.1 - 8.8e-19 67.4 8.7 1e-18 67.1 6.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Glucos_trans_II PF14264.1 EEB09117.1 - 0.097 11.6 7.9 0.11 11.4 5.5 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII MFS_1 PF07690.11 EEB09118.1 - 2.1e-05 23.3 26.0 0.00013 20.7 12.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 EEB09119.1 - 7.5e-104 347.7 29.8 9.2e-104 347.4 20.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB09119.1 - 1.8e-32 112.4 33.8 2.3e-32 112.1 23.5 1.2 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 EEB09120.1 - 8.9e-42 143.5 1.2 2.2e-41 142.2 0.8 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEB09120.1 - 0.045 14.2 0.0 4.9 7.7 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Asp_Glu_race PF01177.17 EEB09121.1 - 7.3e-26 91.4 0.6 8.4e-26 91.2 0.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Cro PF09048.5 EEB09121.1 - 0.038 13.6 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 Cro Uricase PF01014.13 EEB09122.1 - 4.4e-68 227.6 4.0 1.5e-36 125.4 0.8 2.0 2 0 0 2 2 2 2 Uricase Peptidase_M4 PF01447.13 EEB09122.1 - 0.72 9.9 3.1 5.1 7.1 0.1 2.2 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain Transthyretin PF00576.16 EEB09123.1 - 2.3e-34 117.6 0.0 2.5e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 EEB09123.1 - 0.024 14.7 0.2 0.039 14.0 0.1 1.5 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_32N PF00251.15 EEB09124.1 - 2.1e-71 240.7 10.2 1.3e-70 238.2 5.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EEB09124.1 - 0.011 16.1 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EEB09124.1 - 0.1 12.4 1.5 0.61 10.1 0.1 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat WXG100 PF06013.7 EEB09125.1 - 0.005 16.8 1.0 0.005 16.8 0.7 1.9 1 1 0 1 1 1 1 Proteins of 100 residues with WXG Latarcin PF10279.4 EEB09125.1 - 0.0057 16.8 0.2 0.0097 16.0 0.1 1.5 1 0 0 1 1 1 1 Latarcin precursor Syntaxin PF00804.20 EEB09125.1 - 0.013 15.6 5.3 0.025 14.7 3.4 1.6 1 1 1 2 2 2 0 Syntaxin Tweety PF04906.8 EEB09125.1 - 0.016 13.6 1.1 0.018 13.4 0.7 1.2 1 0 0 1 1 1 0 Tweety DUF4145 PF13643.1 EEB09125.1 - 0.017 14.9 1.3 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Filo_VP35 PF02097.10 EEB09125.1 - 0.053 12.7 1.1 0.063 12.4 0.8 1.2 1 0 0 1 1 1 0 Filoviridae VP35 DUF948 PF06103.6 EEB09125.1 - 0.059 13.2 0.8 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0122 PF04297.9 EEB09125.1 - 0.07 13.1 1.5 0.099 12.6 0.2 1.8 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like CH PF00307.26 EEB09125.1 - 0.089 12.8 0.6 0.28 11.2 0.4 1.9 1 1 0 1 1 1 0 Calponin homology (CH) domain DUF2856 PF11043.3 EEB09125.1 - 0.1 12.7 0.2 0.31 11.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2856) Syntaxin-6_N PF09177.6 EEB09125.1 - 0.31 11.4 5.6 0.39 11.1 1.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 EEB09125.1 - 0.34 11.0 4.4 1.3 9.1 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EEB09125.1 - 0.89 9.5 4.8 1.4 8.9 0.9 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 EEB09125.1 - 1 9.0 5.8 1.2 8.8 0.8 2.4 2 1 0 2 2 2 0 Prefoldin subunit Ribosomal_L23eN PF03939.8 EEB09126.1 - 2.9e-20 72.0 7.1 2.9e-20 72.0 5.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EEB09126.1 - 3.1e-18 65.5 2.0 3.1e-18 65.5 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 P2 PF07194.6 EEB09126.1 - 0.13 12.1 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 P2 response regulator binding domain Abhydrolase_1 PF00561.15 EEB09127.1 - 3.8e-25 88.8 0.1 3.3e-23 82.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEB09127.1 - 5.2e-11 42.8 0.3 1.2e-10 41.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEB09127.1 - 0.00064 19.2 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Proteasome PF00227.21 EEB09128.1 - 2.5e-57 193.2 0.1 3.1e-57 192.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB09128.1 - 3.6e-12 45.3 0.3 9.4e-12 44.0 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NUDIX PF00293.23 EEB09129.1 - 2.7e-26 91.7 0.0 3.9e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ResIII PF04851.10 EEB09129.1 - 0.047 13.5 0.3 0.12 12.1 0.1 1.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SDA1 PF05285.7 EEB09130.1 - 2.6e-76 257.0 27.5 2.6e-76 257.0 19.1 3.1 2 2 0 3 3 3 1 SDA1 NUC130_3NT PF08158.7 EEB09130.1 - 4.4e-19 68.5 0.3 1.1e-18 67.2 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain PNPase PF03726.9 EEB09130.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.2 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain CLTH PF10607.4 EEB09131.1 - 1.6e-26 92.7 0.0 1.6e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain BLOC1_2 PF10046.4 EEB09131.1 - 0.11 12.6 1.1 0.26 11.4 0.8 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRM_1 PF00076.17 EEB09132.1 - 5.5e-15 54.7 0.0 8.9e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09132.1 - 1.5e-10 40.8 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEB09132.1 - 6.1e-05 23.3 5.5 0.0001 22.6 0.0 2.6 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEB09132.1 - 0.00042 20.0 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEB09132.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif dsDNA_bind PF01984.15 EEB09132.1 - 0.031 14.2 0.3 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain PAF-AH_p_II PF03403.8 EEB09133.1 - 6.3e-77 258.3 0.0 7.7e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EEB09133.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB09133.1 - 2.7e-05 24.1 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EEB09133.1 - 5.4e-05 22.1 0.0 0.0001 21.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EEB09133.1 - 9.7e-05 21.3 0.1 0.00028 19.8 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EEB09133.1 - 0.0019 18.0 0.3 0.0077 16.0 0.0 2.1 3 0 0 3 3 3 1 Putative lysophospholipase DLH PF01738.13 EEB09133.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.7 1 0 0 1 1 1 0 Dienelactone hydrolase family Pkinase PF00069.20 EEB09134.1 - 3e-68 229.8 0.0 3.9e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09134.1 - 7.3e-35 120.2 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09134.1 - 2.5e-06 26.7 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB09134.1 - 0.00025 20.8 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEB09134.1 - 0.057 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EEB09134.1 - 0.076 12.0 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family B-block_TFIIIC PF04182.7 EEB09134.1 - 0.1 12.4 0.2 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Apc1 PF12859.2 EEB09135.2 - 5.1e-15 55.5 0.2 2.1e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EEB09135.2 - 1.9e-07 30.8 4.5 0.049 13.8 0.0 4.2 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Vezatin PF12632.2 EEB09136.1 - 1.7e-58 197.7 8.8 1.7e-58 197.7 6.1 2.1 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PMT PF02366.13 EEB09137.1 - 3.2e-58 197.0 24.1 3.8e-58 196.7 13.1 2.3 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEB09137.1 - 2.3e-38 131.6 0.2 3.9e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 MIR domain Hydrolase_6 PF13344.1 EEB09138.1 - 4.2e-22 77.9 0.0 8.3e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB09138.1 - 1.1e-20 73.1 0.0 4.5e-20 71.1 0.0 2.1 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EEB09138.1 - 0.00014 22.1 0.0 0.037 14.2 0.0 3.0 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EEB09138.1 - 0.094 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Hydrolase PF00702.21 EEB09138.1 - 0.13 12.7 0.0 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PRP21_like_P PF12230.3 EEB09139.1 - 3.6e-57 193.5 8.1 6.3e-57 192.7 5.6 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EEB09139.1 - 7.4e-36 121.5 1.9 4.3e-19 67.9 0.2 2.3 2 0 0 2 2 2 2 Surp module zf-Di19 PF05605.7 EEB09139.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CDP-OH_P_transf PF01066.16 EEB09140.1 - 8.6e-16 58.0 3.5 8.6e-16 58.0 2.4 2.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Dak1 PF02733.12 EEB09141.1 - 8.4e-138 458.3 5.3 1.3e-137 457.7 3.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EEB09141.1 - 7.8e-50 168.9 0.8 1.6e-49 167.9 0.6 1.6 1 0 0 1 1 1 1 DAK2 domain Kelch_4 PF13418.1 EEB09143.2 - 9e-32 108.6 7.0 2.3e-11 43.2 0.1 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EEB09143.2 - 3e-31 106.8 7.9 1.5e-06 28.1 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EEB09143.2 - 3.4e-30 102.9 6.7 8.1e-08 32.1 0.0 5.9 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EEB09143.2 - 6.5e-23 80.0 0.0 1.2e-05 24.7 0.0 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EEB09143.2 - 1.8e-19 69.2 0.5 4.1e-06 26.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EEB09143.2 - 1.1e-11 43.9 0.9 0.0002 21.0 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Abhydrolase_6 PF12697.2 EEB09144.2 - 7.9e-29 101.1 0.0 1.3e-28 100.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEB09144.2 - 3e-18 66.2 0.0 1e-12 48.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEB09144.2 - 7.6e-13 48.4 0.0 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEB09144.2 - 3.1e-07 30.1 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 EEB09144.2 - 2.4e-06 27.1 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 EEB09144.2 - 0.00011 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.6 EEB09144.2 - 0.00011 21.9 0.1 0.094 12.4 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 EEB09144.2 - 0.00087 18.4 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 EEB09144.2 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EEB09144.2 - 0.0014 18.8 0.2 0.085 13.0 0.0 2.6 2 1 0 2 2 2 1 Thioesterase domain Ndr PF03096.9 EEB09144.2 - 0.0058 15.1 0.0 0.012 14.1 0.0 1.5 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 EEB09144.2 - 0.0063 15.7 0.0 0.16 11.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF2305 PF10230.4 EEB09144.2 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 EEB09144.2 - 0.013 14.9 0.6 0.27 10.6 0.0 2.9 2 1 1 3 3 3 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EEB09144.2 - 0.026 14.1 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EEB09144.2 - 0.052 12.9 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF900 PF05990.7 EEB09144.2 - 0.067 12.5 0.1 0.37 10.0 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0227 PF05728.7 EEB09144.2 - 0.072 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ribosomal_S4e PF00900.15 EEB09145.1 - 6.8e-33 112.1 0.6 1.4e-32 111.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EEB09145.1 - 3e-19 68.5 5.5 6.2e-19 67.5 3.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EEB09145.1 - 3.8e-07 29.4 0.0 8.8e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEB09145.1 - 3.3e-05 23.4 1.3 3.3e-05 23.4 0.9 2.6 3 0 0 3 3 3 1 KOW motif Acatn PF13000.2 EEB09146.1 - 7.3e-150 500.0 32.3 1.6e-80 271.2 8.2 3.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 EF_assoc_1 PF08355.7 EEB09146.1 - 0.11 11.7 0.0 0.75 9.1 0.0 2.3 2 1 1 3 3 3 0 EF hand associated Glyco_hydro_16 PF00722.16 EEB09148.1 - 2.1e-09 36.9 0.0 4.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rick_17kDa_Anti PF05433.10 EEB09148.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Mito_carr PF00153.22 EEB09149.1 - 2.2e-65 216.3 3.8 2.9e-25 87.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DENN PF02141.16 EEB09150.1 - 2.2e-33 115.5 0.2 4.4e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EEB09150.1 - 3.6e-06 26.9 0.3 1.2e-05 25.2 0.2 2.0 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EEB09150.1 - 7.9e-05 22.5 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 uDENN domain Rrp15p PF07890.7 EEB09151.1 - 1.2e-29 102.9 6.7 2e-29 102.2 4.7 1.3 1 0 0 1 1 1 1 Rrp15p Dehydratase_SU PF02287.10 EEB09151.1 - 0.039 13.6 1.8 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Dehydratase small subunit HTH_31 PF13560.1 EEB09151.1 - 7.9 6.7 9.7 1.7 8.9 1.6 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Rhodanese PF00581.15 EEB09152.1 - 4.7e-13 49.4 0.1 9.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Hexokinase_2 PF03727.11 EEB09153.1 - 1.2e-92 309.5 0.0 1.8e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEB09153.1 - 1.1e-77 260.0 0.1 2.6e-77 258.8 0.0 1.6 2 0 0 2 2 2 1 Hexokinase DUF1731 PF08338.6 EEB09153.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) TPP_enzyme_N PF02776.13 EEB09153.1 - 0.058 12.8 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Cullin PF00888.17 EEB09154.2 - 4.7e-150 500.9 22.1 5.8e-150 500.6 15.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEB09154.2 - 1.4e-29 101.6 8.5 7.2e-29 99.4 1.9 3.5 3 0 0 3 3 3 1 Cullin protein neddylation domain HbrB PF08539.6 EEB09154.2 - 0.0042 16.9 2.3 0.044 13.6 0.1 3.2 2 1 0 2 2 2 1 HbrB-like DUF445 PF04286.7 EEB09154.2 - 0.75 9.2 8.4 0.14 11.6 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF445) zf-DNL PF05180.7 EEB09155.1 - 6.8e-31 105.8 1.6 1e-30 105.2 1.1 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EEB09155.1 - 0.0021 17.7 1.7 0.0033 17.0 1.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF2039 PF10217.4 EEB09155.1 - 0.055 13.4 0.9 0.086 12.8 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-DNA_Pol PF08996.5 EEB09155.1 - 0.073 12.4 0.7 0.11 11.7 0.5 1.4 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zinc_ribbon_4 PF13717.1 EEB09155.1 - 0.081 12.6 0.7 3 7.6 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEB09155.1 - 0.12 12.0 0.6 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EEB09155.1 - 0.13 11.9 2.0 11 5.6 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) E7 PF00527.13 EEB09155.1 - 0.75 9.9 5.1 3.4 7.8 2.2 2.5 2 1 1 3 3 3 0 E7 protein, Early protein MBOAT PF03062.14 EEB09156.2 - 4.5e-54 183.7 27.5 4.5e-54 183.7 19.1 2.3 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Dopey_N PF04118.9 EEB09157.2 - 2.1e-93 312.4 0.0 2.1e-93 312.4 0.0 3.6 3 1 1 4 4 4 1 Dopey, N-terminal SLX9 PF15341.1 EEB09158.2 - 4.2e-22 78.8 17.9 4.2e-22 78.8 12.4 1.9 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF3584 PF12128.3 EEB09158.2 - 0.0013 16.2 6.3 0.0015 15.9 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4485 PF14846.1 EEB09158.2 - 0.0059 16.3 2.8 0.0059 16.3 1.9 2.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4485) DUF812 PF05667.6 EEB09158.2 - 0.022 13.2 13.4 0.025 13.1 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IL2 PF00715.12 EEB09158.2 - 0.1 12.3 1.7 0.16 11.6 1.2 1.3 1 0 0 1 1 1 0 Interleukin 2 KilA-N PF04383.8 EEB09158.2 - 2.5 7.7 9.0 4.7 6.8 6.2 1.5 1 1 0 1 1 1 0 KilA-N domain GvpL_GvpF PF06386.6 EEB09158.2 - 8.8 5.8 8.5 0.53 9.8 2.2 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF EXS PF03124.9 EEB09159.1 - 7.6e-69 232.3 18.8 8.6e-69 232.1 13.1 1.0 1 0 0 1 1 1 1 EXS family DUF872 PF05915.7 EEB09159.1 - 0.29 11.0 2.3 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SLD3 PF08639.5 EEB09160.1 - 7.1e-24 84.3 22.0 4.6e-14 51.9 12.5 3.1 1 1 1 2 2 2 2 DNA replication regulator SLD3 Ribosomal_S4 PF00163.14 EEB09161.1 - 2.5e-29 101.5 1.8 4.8e-29 100.5 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEB09161.1 - 1.9e-12 46.4 1.6 1.9e-12 46.4 1.1 2.3 3 0 0 3 3 3 1 S4 domain Ras PF00071.17 EEB09162.1 - 4.5e-48 162.6 0.7 4.6e-48 162.6 0.0 1.3 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EEB09162.1 - 1.9e-16 60.6 0.0 2.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB09162.1 - 2.6e-15 56.1 0.0 3.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEB09162.1 - 1e-05 24.8 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EEB09162.1 - 6.6e-05 22.5 0.1 0.001 18.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EEB09162.1 - 0.00013 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEB09162.1 - 0.00043 20.4 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EEB09162.1 - 0.0013 18.2 0.0 0.0095 15.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEB09162.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EEB09162.1 - 0.0036 17.5 0.0 0.0072 16.6 0.0 1.8 1 1 1 2 2 2 1 ABC transporter DUF258 PF03193.11 EEB09162.1 - 0.006 15.7 0.0 0.025 13.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEB09162.1 - 0.0071 16.3 0.1 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EEB09162.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EEB09162.1 - 0.022 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EEB09162.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEB09162.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EEB09162.1 - 0.04 13.6 0.1 0.15 11.7 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EEB09162.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EEB09162.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEB09162.1 - 0.07 12.8 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EEB09162.1 - 0.081 12.4 0.1 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EEB09162.1 - 0.083 12.3 0.0 0.97 8.9 0.0 2.3 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Spore_IV_A PF09547.5 EEB09162.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Sel1 PF08238.7 EEB09164.1 - 2.9e-19 69.0 30.4 3.8e-06 27.3 0.6 10.6 12 0 0 12 12 12 7 Sel1 repeat Noc2 PF03715.8 EEB09165.2 - 3.2e-59 200.2 6.3 3.2e-59 200.2 4.4 1.6 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.7 EEB09165.2 - 0.00011 20.3 1.7 0.00011 20.3 1.2 3.1 2 1 0 3 3 3 2 Nop14-like family STAT_int PF02865.12 EEB09165.2 - 0.15 12.0 2.6 0.21 11.5 0.2 2.5 2 0 0 2 2 2 0 STAT protein, protein interaction domain PCI PF01399.22 EEB09166.2 - 3e-10 40.3 0.2 6.9e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 PCI domain Coiled-coil_56 PF09813.4 EEB09167.1 - 0.0064 16.4 0.3 0.018 15.0 0.2 1.7 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 VPS28 PF03997.7 EEB09168.1 - 4.9e-52 176.2 2.6 5.8e-52 176.0 1.8 1.1 1 0 0 1 1 1 1 VPS28 protein RNA_pol PF00940.14 EEB09168.1 - 0.027 12.9 0.4 0.04 12.4 0.3 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase CPG4 PF15481.1 EEB09168.1 - 0.036 14.4 0.2 0.075 13.3 0.2 1.6 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 GCFC PF07842.7 EEB09168.1 - 0.062 12.6 0.1 0.98 8.7 0.1 2.1 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein Not3 PF04065.10 EEB09169.1 - 2.2e-92 308.5 26.2 3.7e-92 307.8 18.2 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EEB09169.1 - 2.7e-44 150.2 6.2 2.7e-44 150.2 4.3 2.7 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family V-SNARE PF05008.10 EEB09169.1 - 0.026 14.6 1.4 0.026 14.6 1.0 2.9 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Cep57_MT_bd PF06657.8 EEB09169.1 - 0.026 14.4 0.2 0.026 14.4 0.1 3.1 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 EEB09169.1 - 0.058 12.9 2.1 0.14 11.6 1.4 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) RinB PF06116.7 EEB09169.1 - 0.084 12.4 2.7 0.2 11.3 1.9 1.6 1 0 0 1 1 1 0 Transcriptional activator RinB LepA_C PF06421.7 EEB09170.2 - 8.2e-39 131.8 0.4 2.1e-38 130.5 0.2 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EEB09170.2 - 1e-38 132.6 0.1 5.2e-37 127.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEB09170.2 - 1.3e-18 66.6 0.0 4e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EEB09170.2 - 2.2e-05 24.2 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEB09170.2 - 2.8e-05 24.0 0.0 5.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEB09170.2 - 2.9e-05 23.3 0.0 5.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEB09170.2 - 0.014 14.7 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 Ras family Miro PF08477.8 EEB09170.2 - 0.024 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU_D2 PF03144.20 EEB09170.2 - 0.034 14.2 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Pro_isomerase PF00160.16 EEB09171.1 - 8.2e-45 152.7 0.8 1.3e-44 152.1 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EEB09171.1 - 2.2e-05 24.0 3.8 0.0018 17.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEB09171.1 - 2.2e-05 24.0 5.0 0.018 14.9 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEB09171.1 - 0.00099 18.6 0.8 0.064 12.8 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09171.1 - 0.053 14.1 1.6 0.11 13.1 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEB09171.1 - 0.11 12.4 2.8 0.76 9.7 1.5 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEB09171.1 - 0.2 12.3 5.2 0.69 10.6 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Elf1 PF05129.8 EEB09172.2 - 9.1e-30 102.1 1.1 1.1e-29 101.9 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SCA7 PF08313.7 EEB09172.2 - 0.16 11.6 3.6 0.28 10.8 2.5 1.5 1 1 0 1 1 1 0 SCA7, zinc-binding domain zf-Sec23_Sec24 PF04810.10 EEB09172.2 - 7.3 6.2 6.4 3.9 7.1 0.5 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger UPRTase PF14681.1 EEB09173.2 - 4.1e-78 261.3 0.0 4.7e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEB09173.2 - 4.1e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 EEB09173.2 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Flu_C_NS1 PF03506.8 EEB09173.2 - 0.13 11.9 0.2 0.56 9.9 0.1 1.9 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) TIP49 PF06068.8 EEB09174.1 - 3.6e-190 631.8 0.4 4.2e-190 631.6 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEB09174.1 - 1.7e-10 41.1 0.4 1.9e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEB09174.1 - 2.3e-09 36.6 1.5 0.00018 20.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEB09174.1 - 1.6e-06 28.2 0.0 0.023 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEB09174.1 - 6.5e-05 23.0 0.1 0.34 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEB09174.1 - 0.0007 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEB09174.1 - 0.0025 17.5 0.1 0.81 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEB09174.1 - 0.0055 15.8 0.1 0.52 9.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EEB09174.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EEB09174.1 - 0.0076 15.7 0.1 1.7 8.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EEB09174.1 - 0.012 15.0 0.6 0.044 13.1 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EEB09174.1 - 0.013 16.2 0.1 0.05 14.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EEB09174.1 - 0.017 14.8 0.2 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EEB09174.1 - 0.021 15.1 0.1 0.096 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EEB09174.1 - 0.026 14.3 0.5 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EEB09174.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EEB09174.1 - 0.076 12.2 0.4 0.26 10.5 0.3 1.8 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EEB09174.1 - 0.082 12.3 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Proteasome PF00227.21 EEB09175.1 - 9.7e-50 168.5 0.0 1.4e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEB09175.1 - 8.5e-13 47.3 0.0 1.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_60s PF00428.14 EEB09175.1 - 0.078 13.3 9.4 0.17 12.2 6.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAPPC9-Trs120 PF08626.6 EEB09176.1 - 1.2e-208 695.3 0.2 1.5e-208 695.0 0.1 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HTH_11 PF08279.7 EEB09176.1 - 0.01 15.4 0.0 0.093 12.3 0.0 2.2 2 0 0 2 2 2 0 HTH domain DAO PF01266.19 EEB09177.2 - 4.9e-48 163.8 0.0 5.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEB09177.2 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEB09177.2 - 0.004 17.0 0.1 0.082 12.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEB09177.2 - 0.0046 15.6 0.2 0.096 11.2 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EEB09177.2 - 0.015 15.1 0.2 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EEB09177.2 - 0.11 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MIF4G_like PF09088.6 EEB09178.1 - 3.6e-73 245.1 0.5 3.6e-73 245.1 0.4 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EEB09178.1 - 3.5e-34 118.1 2.4 6.3e-34 117.3 1.6 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EEB09178.1 - 0.015 14.7 3.2 0.041 13.3 2.2 1.8 1 1 0 1 1 1 0 MIF4G domain Spore_III_AE PF09546.5 EEB09178.1 - 0.52 9.2 2.4 0.35 9.7 0.3 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) Iso_dh PF00180.15 EEB09179.2 - 3e-73 246.7 0.0 3.6e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_63 PF03200.11 EEB09180.1 - 6.1e-248 824.7 2.1 7.3e-247 821.2 1.5 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EEB09180.1 - 3.3e-07 29.3 0.1 3.3e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Trehalase GDE_C PF06202.9 EEB09180.1 - 0.015 14.0 0.3 0.032 12.9 0.0 1.7 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 EEB09180.1 - 0.016 13.4 0.0 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MMtag PF10159.4 EEB09181.1 - 1.9e-25 88.7 6.0 1.9e-25 88.7 4.2 2.2 2 1 0 2 2 2 1 Kinase phosphorylation protein Hex_IIIa PF02455.11 EEB09181.1 - 0.1 11.2 6.5 0.11 11.1 4.5 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Zip PF02535.17 EEB09181.1 - 0.77 8.6 6.5 0.78 8.6 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf-met2 PF12907.2 EEB09182.1 - 3.8e-20 71.5 0.0 5.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EEB09182.1 - 9.2e-05 23.0 8.6 0.00015 22.4 6.0 1.3 1 0 0 1 1 1 1 4F5 protein family Rpr2 PF04032.11 EEB09182.1 - 0.026 14.4 0.5 0.03 14.2 0.4 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-rbx1 PF12678.2 EEB09182.1 - 0.055 13.5 0.1 0.06 13.4 0.1 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Di19 PF05605.7 EEB09182.1 - 0.36 11.0 1.9 5.2 7.2 1.0 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cse1 PF08506.5 EEB09183.1 - 1e-147 491.5 5.5 1.6e-147 490.9 3.8 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EEB09183.1 - 1e-146 488.6 0.5 2.1e-146 487.6 0.3 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EEB09183.1 - 7.7e-17 60.9 0.1 3.3e-16 58.9 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEB09183.1 - 0.0056 16.5 2.2 0.031 14.1 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein GIDA PF01134.17 EEB09184.1 - 1.6e-146 488.1 0.0 2.2e-146 487.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EEB09184.1 - 3.4e-12 46.2 0.1 7.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EEB09184.1 - 5.6e-08 32.8 0.3 1.8e-07 31.2 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEB09184.1 - 2.6e-05 23.4 0.2 2.6e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EEB09184.1 - 0.0001 21.3 0.0 0.36 9.6 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEB09184.1 - 0.0008 18.3 2.6 0.0011 17.8 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEB09184.1 - 0.0026 16.2 3.1 0.0052 15.2 0.4 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EEB09184.1 - 0.004 17.5 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEB09184.1 - 0.0046 16.0 0.8 0.053 12.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEB09184.1 - 0.019 15.0 0.1 0.085 12.9 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Syntaxin-6_N PF09177.6 EEB09184.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NAD_binding_9 PF13454.1 EEB09184.1 - 0.028 14.1 2.2 0.031 14.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEB09184.1 - 0.037 12.9 0.2 0.15 10.9 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EEB09184.1 - 0.058 12.9 0.2 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEB09184.1 - 0.11 11.6 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Tfb4 PF03850.9 EEB09185.1 - 2e-103 345.4 3.1 2.3e-103 345.2 2.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF3535 PF12054.3 EEB09185.1 - 0.0012 17.5 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) VWA_2 PF13519.1 EEB09185.1 - 0.012 15.6 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF1246 PF06849.7 EEB09185.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) RNase_T PF00929.19 EEB09186.1 - 6.3e-17 62.3 0.0 1.2e-11 45.2 0.0 2.2 2 0 0 2 2 2 2 Exonuclease SAP PF02037.22 EEB09186.1 - 0.00059 19.2 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain DUF2404 PF10296.4 EEB09187.2 - 2.2e-06 27.7 0.0 6.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SID-1_RNA_chan PF13965.1 EEB09187.2 - 0.031 12.4 0.1 0.048 11.8 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TPR_11 PF13414.1 EEB09188.1 - 8.9e-43 143.7 19.4 8.3e-16 57.3 2.2 5.1 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EEB09188.1 - 9.7e-38 126.2 17.7 2.6e-06 26.7 0.3 8.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EEB09188.1 - 9.9e-34 112.5 14.8 1.2e-06 27.9 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 EEB09188.1 - 6.9e-28 96.1 4.6 2.7e-27 94.2 2.3 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 EEB09188.1 - 3.4e-23 81.7 13.4 4.5e-07 30.3 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09188.1 - 7.4e-18 63.4 12.1 0.014 15.9 0.0 8.3 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEB09188.1 - 5.7e-17 61.8 14.5 3.7e-06 27.1 0.1 5.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EEB09188.1 - 2.7e-16 59.1 5.6 0.00087 19.0 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEB09188.1 - 3.4e-16 58.9 20.6 7e-05 22.6 1.1 5.9 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEB09188.1 - 1.1e-15 56.1 16.3 0.0037 16.9 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EEB09188.1 - 1.6e-14 53.7 13.6 5.1e-05 23.3 1.1 4.8 2 1 4 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEB09188.1 - 1.8e-11 43.2 15.1 0.00084 19.3 0.1 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEB09188.1 - 1.2e-09 37.1 11.9 0.014 15.1 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EEB09188.1 - 1.4e-08 34.1 10.5 0.0023 17.0 0.0 4.7 2 2 0 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEB09188.1 - 1.2e-06 28.3 5.0 0.013 15.3 0.1 5.3 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EEB09188.1 - 2.7e-06 27.4 15.3 0.014 15.8 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EEB09188.1 - 0.00016 21.9 1.7 0.046 13.9 0.0 2.8 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation TPR_10 PF13374.1 EEB09188.1 - 0.00042 20.1 9.6 14 5.7 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 EEB09188.1 - 0.065 13.1 0.4 0.065 13.1 0.2 6.5 8 0 0 8 8 6 0 MIT (microtubule interacting and transport) domain DUF2989 PF11207.3 EEB09188.1 - 0.094 12.1 1.5 10 5.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) RPT PF13446.1 EEB09188.1 - 0.1 12.0 0.6 0.83 9.0 0.0 2.9 4 0 0 4 4 3 0 A repeated domain in UCH-protein TOM20_plant PF06552.7 EEB09188.1 - 0.11 12.1 3.8 0.76 9.3 0.2 3.4 2 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF3856 PF12968.2 EEB09188.1 - 0.12 12.1 5.3 47 3.7 0.2 5.3 5 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.7 EEB09188.1 - 0.24 12.0 4.3 7.5 7.3 0.0 4.5 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.7 EEB09188.1 - 0.26 11.1 13.3 0.49 10.2 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Ku PF02735.11 EEB09189.1 - 4.1e-31 107.9 0.0 8.7e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEB09189.1 - 2e-26 92.8 0.0 3.7e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EEB09189.1 - 6.1e-10 39.0 0.4 1.7e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Fungal_trans PF04082.13 EEB09190.1 - 1.9e-13 49.8 3.4 3.2e-13 49.1 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB09191.1 - 6.2e-11 42.0 9.7 9e-11 41.5 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 EEB09192.1 - 3.1e-97 324.9 0.3 5.2e-97 324.2 0.0 1.4 2 0 0 2 2 2 1 Septin Pet20 PF08692.5 EEB09192.1 - 0.086 12.7 0.5 0.53 10.2 0.3 2.2 1 1 0 1 1 1 0 Mitochondrial protein Pet20 AAA_17 PF13207.1 EEB09192.1 - 0.14 12.9 0.1 0.68 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain SPT2 PF08243.6 EEB09192.1 - 0.94 9.7 0.1 0.94 9.7 0.0 2.6 3 0 0 3 3 3 0 SPT2 chromatin protein ADH_zinc_N_2 PF13602.1 EEB09193.1 - 6.3e-16 59.4 0.0 1.6e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEB09193.1 - 8.4e-16 57.7 0.0 3.7e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEB09193.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEB09193.1 - 1.5e-06 28.3 0.1 3.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EEB09193.1 - 0.00013 21.6 0.3 0.00029 20.4 0.1 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EEB09193.1 - 0.0028 17.2 0.6 0.0063 16.1 0.4 1.5 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YjeF_N PF03853.10 EEB09193.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 EEB09193.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EEB09193.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EEB09193.1 - 0.11 12.3 1.0 0.25 11.1 0.4 1.7 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CheR_N PF03705.10 EEB09194.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain MRP-S25 PF13741.1 EEB09195.2 - 5.8e-74 248.4 5.9 6.6e-74 248.2 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 WD40 PF00400.27 EEB09196.1 - 5.1e-33 111.7 0.8 1.1e-07 31.4 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEB09196.1 - 0.018 13.7 0.2 0.11 11.2 0.0 2.0 1 1 1 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 EEB09196.1 - 0.038 13.6 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CNH PF00780.17 EEB09196.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 CNH domain A_deamin PF02137.13 EEB09197.2 - 4e-65 220.3 0.4 4.9e-65 220.1 0.3 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 EEB09197.2 - 1.7 8.2 4.8 1.1 8.7 1.1 2.1 2 1 0 2 2 2 0 APOBEC-like N-terminal domain Whi5 PF08528.6 EEB09198.1 - 2e-07 30.4 0.2 4.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Whi5 like Stm1_N PF09598.5 EEB09200.2 - 7.5e-11 42.5 8.2 7.5e-11 42.5 5.7 4.4 4 2 0 4 4 4 1 Stm1 UFD1 PF03152.9 EEB09201.1 - 1.1e-73 246.1 0.0 1.4e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.13 EEB09201.1 - 0.008 16.0 0.0 6.6 6.7 0.0 2.6 2 1 0 3 3 3 2 Cell division protein 48 (CDC48), N-terminal domain RRM_1 PF00076.17 EEB09202.1 - 2.3e-09 36.7 0.1 4.7e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09202.1 - 3.6e-08 33.2 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09202.1 - 5.3e-06 26.1 0.0 9.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilX_N PF14341.1 EEB09202.1 - 0.057 13.0 0.9 0.14 11.8 0.6 1.6 1 0 0 1 1 1 0 PilX N-terminal DUF1948 PF09185.5 EEB09202.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Tubulin PF00091.20 EEB09203.1 - 2.9e-69 233.1 0.0 4e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEB09203.1 - 2.9e-49 166.3 0.1 4.9e-49 165.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEB09203.1 - 0.0056 16.1 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain HSF_DNA-bind PF00447.12 EEB09204.2 - 7.1e-34 116.1 0.0 1.6e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Myb_DNA-binding PF00249.26 EEB09205.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain GCIP PF13324.1 EEB09206.1 - 5.1e-05 22.6 2.3 0.00022 20.5 0.7 2.1 1 1 1 2 2 2 2 Grap2 and cyclin-D-interacting ArfGap PF01412.13 EEB09207.1 - 6.6e-34 116.1 1.4 1.4e-33 115.1 0.1 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf ATP-grasp_4 PF13535.1 EEB09207.1 - 0.024 14.3 0.5 0.63 9.7 0.1 2.4 2 0 0 2 2 2 0 ATP-grasp domain PI3_PI4_kinase PF00454.22 EEB09208.2 - 1.7e-16 60.4 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.20 EEB09209.1 - 1.3e-67 227.6 0.0 1.8e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09209.1 - 9.2e-28 97.0 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEB09209.1 - 4.6e-10 39.8 6.2 1.8e-09 37.9 4.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB09209.1 - 2.5e-08 33.2 0.0 3.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB09209.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB09209.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L24e PF01246.15 EEB09210.1 - 7.5e-34 115.4 2.3 7.5e-34 115.4 1.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.4 EEB09210.1 - 0.13 12.3 0.8 0.4 10.7 0.0 2.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) SET PF00856.23 EEB09211.2 - 1.8e-11 44.6 0.4 1.7e-10 41.4 0.0 2.7 2 1 0 2 2 2 1 SET domain PHD PF00628.24 EEB09211.2 - 2e-10 40.1 9.6 4.9e-10 38.9 6.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEB09211.2 - 0.018 14.3 4.2 0.042 13.1 2.9 1.6 1 0 0 1 1 1 0 PHD-finger COX15-CtaA PF02628.10 EEB09212.1 - 8.8e-92 307.1 12.5 1.1e-91 306.8 8.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fer2 PF00111.22 EEB09212.1 - 1.8e-12 46.7 0.3 2.9e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1364 PF07102.7 EEB09212.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Peptidase_S8 PF00082.17 EEB09213.1 - 1.5e-51 175.2 0.1 1.5e-51 175.2 0.1 2.1 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EEB09213.1 - 1.8e-26 91.7 0.5 3.6e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain TMEM154 PF15102.1 EEB09213.1 - 0.094 12.4 0.2 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Pyr_redox_2 PF07992.9 EEB09214.1 - 8.9e-26 91.0 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEB09214.1 - 6.5e-12 45.6 3.1 3.8e-10 40.0 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEB09214.1 - 1.8e-08 34.6 0.1 5.1e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEB09214.1 - 6.5e-05 22.1 2.6 0.051 12.6 0.0 3.1 2 1 1 3 3 3 2 Thi4 family K_oxygenase PF13434.1 EEB09214.1 - 0.014 14.3 0.2 0.26 10.1 0.1 2.1 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEB09214.1 - 0.016 15.2 1.2 0.082 12.9 0.1 2.4 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEB09214.1 - 0.019 13.8 3.3 2 7.1 0.3 2.5 2 2 0 2 2 2 0 FAD binding domain UAF_Rrn10 PF05234.6 EEB09215.1 - 7.3e-13 48.6 0.0 9.3e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 DUF2363 PF10155.4 EEB09215.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) LRR_4 PF12799.2 EEB09216.1 - 5.5e-13 48.2 4.4 0.00012 21.5 0.2 5.3 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EEB09216.1 - 6.7e-13 47.2 0.0 0.14 12.3 0.0 8.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 EEB09216.1 - 1.6e-06 27.3 3.4 7.6 6.9 0.0 6.4 6 2 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EEB09216.1 - 0.0012 18.5 12.2 3.4 7.4 0.2 5.5 3 2 3 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 EEB09216.1 - 0.06 13.5 8.3 45 4.9 0.0 5.9 6 0 0 6 6 6 0 Leucine rich repeat Glyco_transf_34 PF05637.7 EEB09217.1 - 8.7e-79 264.3 0.3 1e-78 264.1 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EEB09217.1 - 0.0036 17.1 0.1 0.0078 16.0 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.9 EEB09217.1 - 0.021 14.1 0.0 0.56 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF273 Rer1 PF03248.8 EEB09218.1 - 1.5e-75 252.6 10.8 1.6e-75 252.5 7.5 1.0 1 0 0 1 1 1 1 Rer1 family Sod_Cu PF00080.15 EEB09219.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) DJ-1_PfpI PF01965.19 EEB09220.1 - 7e-30 103.4 0.0 8.4e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEB09220.1 - 3.1e-12 46.0 0.0 3.6e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase RRM_1 PF00076.17 EEB09221.1 - 3.1e-19 68.3 0.0 5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09221.1 - 1.6e-09 37.5 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09221.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPT PF03151.11 EEB09222.1 - 5.3e-31 107.3 12.9 5.3e-31 107.3 9.0 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEB09222.1 - 1.9e-05 23.7 12.1 1.9e-05 23.7 8.4 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEB09222.1 - 0.00049 20.1 14.7 0.00049 20.1 10.2 2.5 1 1 2 3 3 3 1 EamA-like transporter family YqfQ PF14181.1 EEB09222.1 - 0.053 13.5 0.5 4.9 7.1 0.2 2.1 2 0 0 2 2 2 0 YqfQ-like protein Orbi_NS3 PF01616.11 EEB09222.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Orbivirus NS3 CAF1 PF04857.15 EEB09223.1 - 1.4e-56 191.7 0.1 1.7e-55 188.2 0.1 2.1 1 1 0 1 1 1 1 CAF1 family ribonuclease RNA_pol_Rpc4 PF05132.9 EEB09224.1 - 1.4e-24 86.5 1.9 5.2e-24 84.6 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase III RPC4 tRNA-synt_2 PF00152.15 EEB09225.1 - 2.9e-75 253.1 0.0 3.8e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EEB09225.1 - 1.4e-09 37.4 0.1 2.1e-05 23.8 0.0 3.3 4 0 0 4 4 4 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EEB09225.1 - 1.8e-08 34.1 0.1 4.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EEB09225.1 - 0.0015 18.1 0.1 0.97 8.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DcpS_C PF11969.3 EEB09226.2 - 1.1e-17 64.2 1.6 2.6e-17 63.1 1.1 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EEB09226.2 - 8e-17 61.5 0.1 1.9e-16 60.4 0.1 1.6 1 1 0 1 1 1 1 HIT domain Orthopox_F14 PF06076.7 EEB09226.2 - 0.048 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Arm PF00514.18 EEB09227.1 - 2.1e-94 306.5 20.0 2e-13 49.5 0.1 9.0 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEB09227.1 - 3.4e-25 88.1 2.1 6.9e-09 35.8 0.0 6.6 2 1 3 6 6 5 5 HEAT repeats IBB PF01749.15 EEB09227.1 - 5.1e-22 77.8 3.1 8.8e-22 77.0 2.2 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EEB09227.1 - 5.8e-22 77.5 9.2 4.7e-09 36.4 0.0 6.8 5 3 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EEB09227.1 - 3.2e-19 67.2 0.8 3.4e-05 23.5 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 EEB09227.1 - 3.6e-10 39.3 0.4 0.00013 21.1 0.0 4.5 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EEB09227.1 - 7.8e-08 31.0 0.2 0.00047 18.5 0.1 2.5 1 1 2 3 3 3 3 Adaptin N terminal region V-ATPase_H_C PF11698.3 EEB09227.1 - 3.6e-07 30.1 0.5 0.12 12.3 0.0 4.9 5 2 0 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 EEB09227.1 - 2.4e-06 27.3 2.8 2.3 8.1 0.0 5.2 3 2 2 5 5 5 3 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EEB09227.1 - 2.4e-06 26.1 0.1 0.011 14.0 0.0 3.5 1 1 2 4 4 4 3 Proteasome non-ATPase 26S subunit CTNNBL PF08216.6 EEB09227.1 - 3.2e-06 26.7 2.4 7.7 6.1 0.0 6.3 5 1 1 6 6 6 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_PBS PF03130.11 EEB09227.1 - 0.00058 20.0 0.6 1.5 9.4 0.0 5.1 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.9 EEB09227.1 - 0.0062 15.6 0.0 0.31 10.1 0.0 3.0 1 1 1 2 2 2 1 V-ATPase subunit H DUF3552 PF12072.3 EEB09227.1 - 0.0068 15.6 4.7 0.012 14.8 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF349 PF03993.7 EEB09227.1 - 0.32 11.1 5.1 0.74 10.0 3.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) BIR PF00653.16 EEB09228.2 - 2.3e-40 136.8 6.4 2.3e-20 72.7 0.1 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EEB09228.2 - 0.00093 18.9 3.2 0.18 11.5 0.2 3.8 3 1 0 3 3 3 2 C3HC zinc finger-like C2 PF00168.25 EEB09229.1 - 1.3e-38 130.7 1.4 3e-16 59.0 0.0 5.5 5 0 0 5 5 5 4 C2 domain DUF2404 PF10296.4 EEB09229.1 - 0.00077 19.5 0.1 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) UPF0262 PF06793.7 EEB09229.1 - 0.22 11.2 0.0 0.54 9.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) DUF4225 PF13988.1 EEB09229.1 - 0.58 9.6 4.7 1.4 8.3 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ribosomal_L35Ae PF01247.13 EEB09230.1 - 8e-40 134.5 0.3 9.1e-40 134.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEB09230.1 - 0.001 18.9 0.0 0.51 10.2 0.0 2.4 2 1 1 3 3 3 2 RimM N-terminal domain GTP_EFTU PF00009.22 EEB09231.2 - 5.2e-61 205.3 0.1 7.4e-61 204.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEB09231.2 - 4.1e-35 119.9 0.0 1.1e-34 118.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEB09231.2 - 6.1e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEB09231.2 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEB09231.2 - 3.1e-12 46.4 0.7 1.8e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB09231.2 - 2.7e-05 24.0 0.1 6.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 EEB09231.2 - 0.13 12.0 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 SUKH-4 immunity protein C2 PF00168.25 EEB09232.1 - 7.9e-23 80.1 0.0 3.5e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain Peptidase_M50B PF13398.1 EEB09232.1 - 0.26 10.6 0.5 0.43 9.9 0.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Tyr-DNA_phospho PF06087.7 EEB09233.1 - 1.1e-102 343.9 0.0 4.8e-102 341.8 0.0 1.8 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEB09233.1 - 0.019 14.7 0.0 0.086 12.5 0.0 2.0 2 0 0 2 2 2 0 PLD-like domain DUF4448 PF14610.1 EEB09234.1 - 2.2e-31 108.8 1.0 2.9e-31 108.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3869 PF12985.2 EEB09234.1 - 0.021 15.2 2.5 0.021 15.2 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) TMEM154 PF15102.1 EEB09234.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family Mst1_SARAH PF11629.3 EEB09235.1 - 0.033 14.0 1.2 0.056 13.2 0.1 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Sec23_helical PF04815.10 EEB09235.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.6 1 1 0 1 1 1 0 Sec23/Sec24 helical domain LisH PF08513.6 EEB09236.1 - 5e-08 32.4 0.9 1.1e-07 31.3 0.6 1.6 1 0 0 1 1 1 1 LisH IATP PF04568.7 EEB09237.1 - 7.3e-12 45.1 0.7 7.7e-12 45.1 0.0 1.5 2 0 0 2 2 1 1 Mitochondrial ATPase inhibitor, IATP DUF342 PF03961.8 EEB09237.1 - 0.0016 16.9 1.4 0.0016 16.9 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) KxDL PF10241.4 EEB09237.1 - 0.0026 17.6 0.5 0.004 17.0 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein IncA PF04156.9 EEB09237.1 - 0.0031 17.1 1.8 0.0031 17.1 1.2 1.1 1 0 0 1 1 1 1 IncA protein Spectrin PF00435.16 EEB09237.1 - 0.0031 17.7 5.8 0.0042 17.3 4.0 1.1 1 0 0 1 1 1 1 Spectrin repeat BLOC1_2 PF10046.4 EEB09237.1 - 0.022 14.9 1.8 0.032 14.3 1.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4191 PF13829.1 EEB09237.1 - 0.029 13.5 0.3 0.032 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RNB PF00773.14 EEB09237.1 - 0.058 12.6 2.6 0.072 12.3 1.8 1.1 1 0 0 1 1 1 0 RNB domain AcylCoA_dehyd_C PF12186.3 EEB09237.1 - 0.11 12.3 1.6 0.18 11.6 1.1 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal zf-CpG_bind_C PF12269.3 EEB09237.1 - 0.11 11.9 4.9 0.13 11.7 3.4 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Seryl_tRNA_N PF02403.17 EEB09237.1 - 0.17 11.9 6.2 0.21 11.6 4.3 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HemX PF04375.9 EEB09237.1 - 0.18 10.3 2.9 0.21 10.1 2.0 1.1 1 0 0 1 1 1 0 HemX DASH_Dad2 PF08654.5 EEB09237.1 - 0.21 11.6 4.5 0.13 12.2 2.0 1.5 1 1 1 2 2 2 0 DASH complex subunit Dad2 V_ATPase_I PF01496.14 EEB09237.1 - 0.27 9.0 2.2 0.27 9.0 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 EEB09237.1 - 0.37 10.0 2.8 0.43 9.8 1.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2570 PF10828.3 EEB09237.1 - 0.43 10.2 3.5 0.53 9.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF573 PF04504.9 EEB09237.1 - 0.51 10.6 5.2 0.41 10.9 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF573 SlyX PF04102.7 EEB09237.1 - 0.88 9.9 7.3 1.6 9.1 5.1 1.5 1 1 0 1 1 1 0 SlyX TMPIT PF07851.8 EEB09237.1 - 1 8.4 6.6 1.2 8.1 4.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3513 PF12026.3 EEB09237.1 - 1.4 8.3 7.0 1.6 8.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Glyco_tran_28_C PF04101.11 EEB09237.1 - 1.5 8.4 4.3 2 8.0 3.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CENP-H PF05837.7 EEB09237.1 - 4.4 7.5 8.5 4.7 7.4 4.9 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2422 PF10337.4 EEB09238.1 - 1.4e-71 241.6 14.3 1.5e-69 234.9 6.5 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EEB09238.1 - 6.2e-59 199.3 0.0 9.4e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EEB09238.1 - 8.8e-07 28.8 15.5 8.8e-07 28.8 10.7 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EEB09238.1 - 0.41 9.2 10.8 1.3 7.5 7.5 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter Utp14 PF04615.8 EEB09239.1 - 4.6e-182 606.9 73.9 4.6e-182 606.9 51.2 2.0 1 1 1 2 2 2 1 Utp14 protein S-methyl_trans PF02574.11 EEB09240.1 - 8.4e-20 71.2 0.0 9.9e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Metallophos PF00149.23 EEB09241.1 - 1.5e-39 135.4 0.1 2e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 EEB09242.1 - 9.6e-86 281.4 6.2 4e-21 74.4 0.6 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09242.1 - 5e-58 193.0 2.4 9.1e-18 64.0 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09242.1 - 4.3e-44 148.1 1.2 4.9e-11 42.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEB09242.1 - 1.2e-28 98.5 2.3 3.4e-28 97.0 0.7 2.5 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EEB09242.1 - 1.2e-06 28.2 8.3 0.14 12.0 2.6 4.4 3 1 1 4 4 4 3 RNA binding motif Nup35_RRM_2 PF14605.1 EEB09242.1 - 0.00011 21.8 0.4 2.1 8.1 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EEB09242.1 - 0.00011 22.3 0.0 2.6 8.3 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EEB09242.1 - 0.006 16.3 1.7 1.8 8.3 0.0 3.8 4 0 0 4 4 4 1 Limkain b1 DnaI_N PF07319.6 EEB09242.1 - 0.089 13.0 5.7 0.12 12.5 0.9 3.0 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus OB_RNB PF08206.6 EEB09242.1 - 0.76 9.3 2.8 5.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 EEB09244.1 - 1.2e-93 313.7 0.3 2.5e-93 312.7 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EEB09244.1 - 0.039 13.5 0.5 0.15 11.7 0.4 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Usp PF00582.21 EEB09246.1 - 5.4e-25 88.2 0.3 5.4e-25 88.2 0.2 2.0 2 0 0 2 2 2 1 Universal stress protein family Pam17 PF08566.5 EEB09247.2 - 2.9e-57 193.1 0.1 8.4e-57 191.6 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial import protein Pam17 SART-1 PF03343.8 EEB09248.2 - 6.6e-94 315.4 51.1 8e-94 315.1 35.4 1.0 1 0 0 1 1 1 1 SART-1 family Prenyltrans PF00432.16 EEB09249.1 - 9.2e-60 197.8 2.0 2.2e-14 52.6 0.1 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEB09249.1 - 1.3e-31 109.3 0.0 1.8e-11 44.4 0.0 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEB09249.1 - 1.6e-09 37.7 0.0 2.9e-05 24.0 0.0 3.4 3 1 1 4 4 4 2 Prenyltransferase-like Rop PF01815.11 EEB09249.1 - 0.26 10.7 3.8 0.59 9.6 0.0 3.1 4 0 0 4 4 4 0 Rop protein Ribonuc_2-5A PF06479.7 EEB09250.1 - 9.5e-47 158.0 0.3 2.1e-46 156.9 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EEB09250.1 - 7.1e-40 136.8 0.0 1.4e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09250.1 - 6.3e-22 77.8 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EEB09250.1 - 7.8e-11 40.9 1.4 0.00035 19.9 0.0 3.8 3 1 1 4 4 4 3 PQQ enzyme repeat PQQ_2 PF13360.1 EEB09250.1 - 2.6e-08 33.6 0.0 1.5e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain Ycf1 PF05758.7 EEB09250.1 - 0.0091 13.7 0.0 0.013 13.2 0.0 1.1 1 0 0 1 1 1 1 Ycf1 PQQ_3 PF13570.1 EEB09250.1 - 0.015 15.5 0.0 16 5.8 0.0 3.5 3 1 0 3 3 3 0 PQQ-like domain Kdo PF06293.9 EEB09250.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEB09250.1 - 0.019 13.9 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like 4F5 PF04419.9 EEB09251.1 - 8e-06 26.4 19.3 8.8e-05 23.1 13.4 2.3 1 1 0 1 1 1 1 4F5 protein family DUF3682 PF12446.3 EEB09251.1 - 0.19 12.0 2.3 0.19 12.0 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) zf-CCHC PF00098.18 EEB09252.2 - 1.5e-06 27.8 2.1 3.6e-06 26.6 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EEB09252.2 - 0.0048 16.9 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein EF-hand_6 PF13405.1 EEB09252.2 - 0.056 13.3 0.1 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain zf-CCHC_5 PF14787.1 EEB09252.2 - 0.18 11.2 5.3 0.37 10.2 3.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HAD PF12710.2 EEB09253.1 - 1e-18 68.2 0.1 1.7e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB09253.1 - 1.3e-13 51.8 2.6 8e-12 46.0 1.8 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEB09253.1 - 1.2e-11 44.6 0.6 2.2e-08 33.9 0.1 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEB09253.1 - 0.00014 21.1 0.0 0.00079 18.6 0.0 1.9 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 EEB09253.1 - 0.00019 21.6 0.0 0.00052 20.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EEB09253.1 - 0.055 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.2 EEB09253.1 - 0.13 11.8 0.0 0.59 9.7 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase AHSA1 PF08327.6 EEB09254.2 - 0.062 13.4 0.1 0.068 13.2 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein zf-DHHC PF01529.15 EEB09255.1 - 1.3e-39 135.3 12.8 1.3e-39 135.3 8.9 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase ABC2_membrane_3 PF12698.2 EEB09255.1 - 0.029 13.3 0.4 0.029 13.3 0.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein zf-RanBP PF00641.13 EEB09255.1 - 4.5 6.4 7.1 0.28 10.3 1.0 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF2348 PF09807.4 EEB09256.1 - 5.3e-09 35.5 0.1 8.8e-09 34.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EEB09256.1 - 0.004 16.2 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 EEB09256.1 - 0.032 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Methyltransf_23 PF13489.1 EEB09257.1 - 1.5e-18 67.0 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB09257.1 - 1.6e-16 60.5 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB09257.1 - 2.2e-13 50.0 0.0 2.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB09257.1 - 5.5e-13 49.2 0.0 9.5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB09257.1 - 9.1e-10 39.1 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB09257.1 - 1.8e-08 34.6 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB09257.1 - 1.7e-07 30.7 0.0 3.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EEB09257.1 - 2e-06 27.0 0.0 6.9e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEB09257.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EEB09257.1 - 4.2e-05 22.6 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) NNMT_PNMT_TEMT PF01234.12 EEB09257.1 - 0.00016 20.7 0.0 0.0021 17.0 0.0 1.9 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family NodS PF05401.6 EEB09257.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF938 PF06080.7 EEB09257.1 - 0.0015 18.0 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 EEB09257.1 - 0.0093 15.0 0.0 0.033 13.2 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EEB09257.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EEB09257.1 - 0.016 16.0 0.0 0.027 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HHA PF05321.6 EEB09257.1 - 0.046 13.8 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Haemolysin expression modulating protein Methyltransf_16 PF10294.4 EEB09257.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Rogdi_lz PF10259.4 EEB09258.1 - 2.7e-22 79.1 1.7 5.6e-17 61.7 0.2 2.1 1 1 0 2 2 2 2 Rogdi leucine zipper containing protein FHA PF00498.21 EEB09259.1 - 2e-18 66.2 0.1 4.2e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 EEB09261.1 - 6.3e-39 133.6 0.0 7.9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09261.1 - 1.1e-14 54.1 0.0 1.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB09261.1 - 5.1e-07 29.6 0.0 0.002 17.9 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family ox_reductase_C PF08635.5 EEB09262.1 - 9.5e-70 232.5 0.0 1.3e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EEB09262.1 - 9.6e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEB09262.1 - 0.016 14.9 0.0 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain FAD_binding_1 PF00667.15 EEB09263.2 - 2.3e-53 180.8 0.0 4.4e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEB09263.2 - 3.7e-13 50.0 0.0 3.5e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain RICTOR_N PF14664.1 EEB09264.1 - 4.7e-102 341.3 5.2 7.5e-102 340.6 2.9 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EEB09264.1 - 5.9e-82 274.0 8.8 1.1e-80 269.9 0.4 4.3 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EEB09264.1 - 2.4e-32 111.2 1.5 2.9e-29 101.3 0.1 4.0 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EEB09264.1 - 1.2e-25 89.1 0.2 9.3e-22 76.7 0.0 5.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EEB09264.1 - 1.4e-12 47.1 10.0 3.8e-12 45.7 6.9 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 EEB09264.1 - 0.0093 15.9 5.6 0.028 14.3 3.9 1.8 1 0 0 1 1 1 1 Up-regulated During Septation KLRAQ PF10205.4 EEB09264.1 - 9.8 6.2 13.3 21 5.1 0.1 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Pkinase PF00069.20 EEB09265.1 - 3e-66 223.2 0.0 4e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09265.1 - 7.4e-44 149.7 0.0 1.1e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09265.1 - 4.8e-07 29.0 0.0 3.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEB09265.1 - 0.031 13.3 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEB09265.1 - 0.19 11.0 0.1 0.51 9.6 0.1 1.6 1 1 0 1 1 1 0 RIO1 family RhoGAP PF00620.22 EEB09266.1 - 4.5e-35 120.4 0.0 7.7e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF2458 PF10454.4 EEB09267.1 - 7.2e-26 90.8 3.9 2.3e-24 86.0 2.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) RCC1 PF00415.13 EEB09268.1 - 1.6e-66 220.2 4.4 7.8e-12 45.2 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEB09268.1 - 4.3e-31 105.8 37.4 1.6e-07 30.7 0.6 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.6 EEB09268.1 - 0.0012 18.6 0.0 2.3 8.1 0.0 3.6 4 0 0 4 4 4 2 Beta-propeller repeat PQQ_3 PF13570.1 EEB09268.1 - 0.67 10.3 4.3 49 4.3 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.20 EEB09269.1 - 2e-37 128.7 0.0 3.7e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09269.1 - 2.5e-30 105.4 0.0 3.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09269.1 - 0.02 13.8 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEB09269.1 - 0.2 11.3 0.0 1.9 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.17 EEB09270.2 - 2.9e-10 40.4 3.1 1.4e-08 34.9 0.5 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEB09270.2 - 0.00088 19.1 0.3 0.8 9.5 0.1 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Isochorismatase PF00857.15 EEB09271.1 - 6.2e-27 94.6 0.0 7.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Pkinase PF00069.20 EEB09272.2 - 4.9e-72 242.1 0.0 1.9e-71 240.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09272.2 - 3e-51 173.9 0.0 9.3e-51 172.3 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.18 EEB09272.2 - 0.022 14.5 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EEB09273.1 - 1.5e-47 161.9 0.0 2.3e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09273.1 - 1.6e-26 92.9 0.0 3.2e-26 91.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09273.1 - 5.5e-08 32.1 0.0 8.4e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB09273.1 - 0.00091 18.3 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Septin PF00735.13 EEB09274.2 - 2.1e-83 279.6 0.0 2.6e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Septin Bax1-I PF01027.15 EEB09275.1 - 5.3e-44 150.2 35.6 6.4e-44 150.0 24.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4383 PF14325.1 EEB09275.1 - 0.71 9.8 11.9 3.2 7.7 7.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) SAC3_GANP PF03399.11 EEB09276.1 - 1.3e-59 201.2 2.3 3.7e-59 199.7 1.6 1.8 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEB09276.1 - 0.0098 15.6 0.0 0.052 13.3 0.0 2.3 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Nexin_C PF08628.7 EEB09276.1 - 0.014 15.5 2.2 0.053 13.6 1.6 2.1 1 1 0 1 1 1 0 Sorting nexin C terminal tRNA-synt_1b PF00579.20 EEB09277.1 - 1.8e-69 234.1 0.0 2.3e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EEB09277.1 - 0.023 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 S4 domain Clat_adaptor_s PF01217.15 EEB09278.1 - 1.2e-12 47.7 0.1 1.8e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S5 PF00333.15 EEB09279.1 - 2.8e-28 97.4 1.3 2.8e-28 97.4 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EEB09279.1 - 7.2e-21 73.2 0.2 1.4e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S10 PF00338.17 EEB09280.1 - 1.6e-31 107.9 0.9 2.1e-31 107.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e AAA PF00004.24 EEB09281.1 - 7.5e-46 155.6 0.0 1.8e-45 154.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEB09281.1 - 2.1e-09 37.2 0.1 6e-09 35.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEB09281.1 - 2.6e-07 30.7 0.0 7.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEB09281.1 - 4.7e-07 29.9 0.0 1.4e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEB09281.1 - 5.6e-07 29.7 0.2 0.0005 20.2 0.0 2.9 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 EEB09281.1 - 4.6e-06 25.7 0.0 7.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EEB09281.1 - 0.00011 21.3 0.0 0.00026 20.1 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEB09281.1 - 0.00023 21.9 0.0 0.00066 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EEB09281.1 - 0.00023 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEB09281.1 - 0.00028 20.8 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EEB09281.1 - 0.00038 20.0 0.0 0.0052 16.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEB09281.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EEB09281.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EEB09281.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EEB09281.1 - 0.0016 18.1 1.3 0.049 13.2 0.0 3.2 3 1 1 4 4 4 1 NACHT domain AAA_30 PF13604.1 EEB09281.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EEB09281.1 - 0.0022 17.7 0.1 0.0098 15.6 0.1 2.1 2 1 0 2 2 2 1 NTPase Mg_chelatase PF01078.16 EEB09281.1 - 0.0038 16.4 0.2 0.013 14.7 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EEB09281.1 - 0.005 15.6 0.0 0.01 14.6 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 EEB09281.1 - 0.0054 16.2 0.5 0.95 8.9 0.0 3.2 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_25 PF13481.1 EEB09281.1 - 0.0066 15.8 1.0 0.097 12.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB09281.1 - 0.0067 16.7 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEB09281.1 - 0.0074 15.8 0.0 0.027 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEB09281.1 - 0.0087 15.7 0.0 0.04 13.6 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EEB09281.1 - 0.009 15.8 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EEB09281.1 - 0.0093 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EEB09281.1 - 0.01 15.2 0.0 0.034 13.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.13 EEB09281.1 - 0.011 15.4 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.1 EEB09281.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EEB09281.1 - 0.041 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase T2SE PF00437.15 EEB09281.1 - 0.052 12.4 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EEB09281.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EEB09281.1 - 0.083 11.9 0.6 0.83 8.7 0.0 2.5 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.17 EEB09281.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ribosomal_L15e PF00827.12 EEB09282.1 - 1.4e-88 295.4 8.9 1.7e-88 295.1 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 SH3_9 PF14604.1 EEB09283.2 - 4.5e-27 93.3 0.4 1.3e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEB09283.2 - 4.1e-25 86.8 0.0 3.9e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 EEB09283.2 - 2.2e-21 75.8 5.0 1.8e-20 72.9 0.8 3.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EEB09283.2 - 6.7e-19 67.1 0.0 1.7e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EEB09283.2 - 2.1e-12 46.5 14.0 3.6e-12 45.8 9.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myosin_tail_1 PF01576.14 EEB09283.2 - 0.18 9.5 9.0 0.32 8.6 0.0 2.0 2 0 0 2 2 2 0 Myosin tail Syntaxin PF00804.20 EEB09283.2 - 0.26 11.4 0.1 0.26 11.4 0.1 3.3 4 1 0 4 4 4 0 Syntaxin DUF1640 PF07798.6 EEB09283.2 - 0.82 9.6 8.0 7.5 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) DEAD PF00270.24 EEB09284.1 - 1.5e-34 118.9 1.6 6.8e-34 116.7 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09284.1 - 5.5e-24 83.8 0.4 1.5e-23 82.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEB09284.1 - 0.0069 16.5 0.0 0.044 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EEB09284.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 EEB09284.1 - 0.021 14.3 0.0 0.069 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Met_synt_B12 PF02965.12 EEB09284.1 - 0.039 13.1 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain CMS1 PF14617.1 EEB09284.1 - 0.08 11.9 0.1 0.08 11.9 0.1 2.6 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Spermine_synth PF01564.12 EEB09285.1 - 4e-99 330.5 0.0 5.2e-99 330.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EEB09285.1 - 0.00027 20.5 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EEB09285.1 - 0.00035 19.6 0.0 0.00057 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EEB09285.1 - 0.001 19.4 0.1 0.0059 17.0 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB09285.1 - 0.0037 17.8 0.0 0.0083 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB09285.1 - 0.0063 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB09285.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EEB09285.1 - 0.022 14.4 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEB09285.1 - 0.054 13.9 0.0 0.35 11.4 0.0 2.2 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.13 EEB09285.1 - 0.1 11.7 0.5 0.8 8.8 0.2 2.2 1 1 1 2 2 2 0 O-methyltransferase tRNA-synt_1c PF00749.16 EEB09286.2 - 1.9e-101 338.8 0.0 2.7e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EEB09286.2 - 3.4e-44 150.2 2.3 6.6e-44 149.3 1.6 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EEB09286.2 - 3.6e-33 114.6 0.2 1.2e-32 112.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EEB09286.2 - 1.4e-15 57.7 1.6 3.5e-15 56.4 1.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RE_MamI PF09567.5 EEB09286.2 - 0.033 13.2 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 MamI restriction endonuclease Glyco_hydro_72 PF03198.9 EEB09287.1 - 7.8e-138 458.7 5.8 9.6e-138 458.4 4.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Proteasom_Rpn13 PF04683.8 EEB09288.1 - 1.3e-29 102.0 0.3 2.1e-29 101.4 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor PRCC PF10253.4 EEB09288.1 - 3.5 8.2 5.9 8.7 6.9 4.2 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.20 EEB09289.1 - 4.4e-69 232.5 0.0 6e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09289.1 - 8.4e-36 123.3 0.0 1.4e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB09289.1 - 4e-05 23.4 0.0 0.0023 17.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEB09289.1 - 0.0031 16.5 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EEB09289.1 - 0.011 15.3 0.0 0.041 13.4 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EEB09289.1 - 0.018 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family dUTPase PF00692.14 EEB09290.1 - 7.3e-42 141.8 0.0 8.1e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase mRNA_triPase PF02940.10 EEB09291.1 - 7.3e-52 176.2 0.1 1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Gly_radical PF01228.16 EEB09291.1 - 0.094 13.0 0.2 1.2 9.5 0.1 2.4 1 1 1 2 2 2 0 Glycine radical Snf7 PF03357.16 EEB09292.1 - 4.8e-29 100.9 18.9 5.7e-29 100.6 13.1 1.0 1 0 0 1 1 1 1 Snf7 Snapin_Pallidin PF14712.1 EEB09292.1 - 0.18 12.1 6.9 0.12 12.6 3.3 1.9 1 1 1 2 2 2 0 Snapin/Pallidin DUF3662 PF12401.3 EEB09292.1 - 0.24 11.5 3.4 3.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2662) HSCB_C PF07743.8 EEB09292.1 - 0.48 10.9 10.4 3.9 8.0 0.7 2.6 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Peptidase_S46 PF10459.4 EEB09292.1 - 0.55 8.5 10.2 0.66 8.3 7.0 1.0 1 0 0 1 1 1 0 Peptidase S46 YlqD PF11068.3 EEB09292.1 - 0.56 10.2 15.9 1.9 8.5 4.0 2.2 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.10 EEB09292.1 - 0.65 9.1 8.4 0.83 8.7 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.1 EEB09292.1 - 2.9 6.7 12.8 1.4 7.8 7.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4208 PF13907.1 EEB09292.1 - 8.5 6.6 6.7 12 6.1 0.1 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4208) KOW PF00467.24 EEB09293.1 - 0.0028 17.3 1.5 0.0058 16.3 1.0 1.5 1 0 0 1 1 1 1 KOW motif SBDS_C PF09377.5 EEB09294.1 - 1.6e-41 140.9 2.9 2.3e-41 140.4 0.9 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EEB09294.1 - 5e-34 115.9 1.5 1e-33 114.9 1.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myc_N PF01056.13 EEB09294.1 - 0.042 13.0 0.1 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Brix PF04427.13 EEB09295.1 - 1.1e-40 139.4 0.2 1.7e-40 138.7 0.1 1.3 1 0 0 1 1 1 1 Brix domain MRP-L28 PF09812.4 EEB09296.1 - 5.8e-18 65.2 1.3 6.7e-18 64.9 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DDE_Tnp_1_7 PF13843.1 EEB09296.1 - 0.027 13.5 0.1 0.031 13.3 0.1 1.0 1 0 0 1 1 1 0 Transposase IS4 Ribosom_S12_S23 PF00164.20 EEB09297.1 - 1.2e-47 160.3 2.0 1.4e-47 160.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Hexokinase_2 PF03727.11 EEB09298.1 - 3e-71 239.4 0.0 4.5e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEB09298.1 - 2.7e-68 229.3 0.1 4.3e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.27 EEB09299.2 - 2.9e-08 33.2 7.7 0.0016 18.2 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 EEB09299.2 - 0.08 13.0 8.1 0.33 11.0 5.6 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 EEB09299.2 - 1.7 8.3 13.2 0.026 14.2 1.6 2.6 2 0 0 2 2 2 0 PHD-finger PROCN PF08083.6 EEB09300.1 - 1.1e-223 742.1 4.4 2.1e-223 741.2 3.0 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EEB09300.1 - 4.3e-126 418.8 1.1 8.1e-126 417.9 0.8 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EEB09300.1 - 3.3e-91 302.8 1.8 8.7e-91 301.4 1.3 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EEB09300.1 - 3e-76 254.2 1.3 6.9e-76 253.0 0.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EEB09300.1 - 1.3e-67 225.6 0.1 2.6e-67 224.6 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EEB09300.1 - 2.9e-44 149.7 0.0 7.4e-44 148.4 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EEB09300.1 - 1.2e-42 143.7 0.0 3.2e-42 142.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EEB09300.1 - 7.1e-06 25.7 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RasGAP_C PF03836.10 EEB09301.1 - 2.4e-44 150.4 9.5 1.4e-43 148.0 5.5 3.0 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EEB09301.1 - 4.9e-29 101.4 0.2 4.9e-29 101.4 0.1 2.6 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EEB09301.1 - 2.8e-18 63.7 26.3 0.18 11.5 0.0 12.0 12 0 0 12 12 12 8 IQ calmodulin-binding motif CH PF00307.26 EEB09301.1 - 1.3e-13 50.8 0.0 5.8e-13 48.8 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EEB09301.1 - 0.011 15.3 0.0 0.05 13.2 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain HMG_CoA_synt_C PF08540.5 EEB09302.2 - 6.7e-111 370.2 0.5 8.3e-111 369.9 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEB09302.2 - 3.7e-83 277.3 1.2 1.1e-82 275.8 0.4 1.9 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF4078 PF13300.1 EEB09303.1 - 2.6e-21 75.5 8.6 2.6e-21 75.5 6.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CENP-B_N PF04218.8 EEB09303.1 - 0.025 13.9 0.0 0.088 12.2 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HAD_2 PF13419.1 EEB09304.1 - 4.2e-19 69.4 0.0 5.3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB09304.1 - 8.5e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEB09304.1 - 3.7e-06 27.4 0.0 7.5e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATG11 PF10377.4 EEB09305.1 - 5e-29 100.8 0.3 5e-29 100.8 0.2 3.0 2 1 1 3 3 3 1 Autophagy-related protein 11 DUF1765 PF08578.5 EEB09306.1 - 2.5e-25 88.9 4.4 4.6e-25 88.0 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SH3_1 PF00018.23 EEB09307.1 - 8.5e-12 44.2 0.0 1.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEB09307.1 - 1e-11 44.2 0.0 2.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEB09307.1 - 2.2e-08 33.4 0.0 3.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EEB09307.1 - 0.00028 20.9 0.2 0.00057 20.0 0.1 1.5 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sugar_tr PF00083.19 EEB09308.1 - 4.3e-113 378.2 27.3 5e-113 378.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB09308.1 - 1.4e-30 106.2 24.9 1.4e-30 106.2 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEB09308.1 - 1.7e-08 33.1 2.9 1.7e-08 33.1 2.0 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EEB09309.1 - 7.6e-60 202.2 0.0 1.1e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09309.1 - 2.4e-32 112.0 0.0 4e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09309.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEB09309.1 - 5.5e-05 23.0 0.5 0.0012 18.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEB09309.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEB09309.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PPP4R2 PF09184.6 EEB09309.1 - 1.4 8.4 5.0 0.13 11.7 0.2 1.6 2 0 0 2 2 2 0 PPP4R2 Remorin_N PF03766.8 EEB09309.1 - 7.3 6.4 7.3 0.34 10.7 0.2 2.5 3 0 0 3 3 3 0 Remorin, N-terminal region HEAT_2 PF13646.1 EEB09310.1 - 2.1e-07 31.1 2.3 0.00025 21.2 0.2 5.3 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.17 EEB09310.1 - 2.7e-07 30.0 9.7 0.18 11.9 0.0 7.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EEB09310.1 - 0.03 14.8 10.0 0.16 12.4 0.1 5.3 5 0 0 5 5 5 0 HEAT-like repeat DUF2435 PF10363.4 EEB09310.1 - 0.27 11.1 5.5 2.3 8.1 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) Ras PF00071.17 EEB09311.1 - 9e-53 177.9 0.0 1.1e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB09311.1 - 9.2e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB09311.1 - 2.6e-07 30.0 0.0 3.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HSP70 PF00012.15 EEB09312.1 - 2.9e-168 560.5 0.6 3.5e-168 560.2 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEB09312.1 - 1.2e-10 40.5 0.2 1.3e-09 37.1 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 EEB09312.1 - 0.00026 20.8 1.2 0.2 11.4 0.0 3.6 2 1 0 2 2 2 2 Cell division protein FtsA PilM_2 PF11104.3 EEB09312.1 - 0.0019 17.1 0.0 0.01 14.7 0.0 2.2 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; FHA PF00498.21 EEB09313.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain V-SNARE_C PF12352.3 EEB09314.1 - 1.7e-14 53.6 2.3 2.1e-14 53.3 0.4 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEB09314.1 - 5.8e-07 29.1 1.8 4.1e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 Sec20 T4SS PF07996.6 EEB09314.1 - 0.0012 18.6 0.5 0.0021 17.9 0.3 1.3 1 0 0 1 1 1 1 Type IV secretion system proteins Snapin_Pallidin PF14712.1 EEB09314.1 - 0.014 15.6 1.9 0.016 15.4 0.4 1.7 2 0 0 2 2 2 0 Snapin/Pallidin Med9 PF07544.8 EEB09314.1 - 0.016 14.9 0.4 0.047 13.4 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.13 EEB09314.1 - 0.022 13.7 1.6 0.038 13.0 0.8 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein P5-ATPase PF12409.3 EEB09314.1 - 0.33 10.8 2.5 0.2 11.5 0.3 1.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter HTH_8 PF02954.14 EEB09314.1 - 0.36 10.4 2.1 0.56 9.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Peptidase_M48 PF01435.13 EEB09315.1 - 3e-35 121.8 0.3 5.5e-35 120.9 0.2 1.5 1 1 0 1 1 1 1 Peptidase family M48 Tmemb_14 PF03647.8 EEB09316.1 - 2.1e-17 63.2 7.0 2.6e-17 62.9 4.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Romo1 PF10247.4 EEB09316.1 - 7.5 6.8 8.2 11 6.2 0.6 3.3 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Phytochelatin PF05023.9 EEB09317.1 - 8.7e-82 273.2 0.0 1.8e-81 272.1 0.0 1.5 2 0 0 2 2 2 1 Phytochelatin synthase Clathrin_lg_ch PF01086.12 EEB09318.2 - 2.2e-50 171.7 14.1 2.5e-50 171.4 9.8 1.0 1 0 0 1 1 1 1 Clathrin light chain OmpH PF03938.9 EEB09318.2 - 0.00049 20.0 10.2 0.00049 20.0 7.1 1.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EEB09318.2 - 0.024 13.6 5.1 0.032 13.1 3.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_int_SAM_5 PF13102.1 EEB09318.2 - 2.2 8.2 10.7 0.75 9.7 5.3 1.8 2 1 0 2 2 2 0 Phage integrase SAM-like domain CDC37_N PF03234.9 EEB09319.1 - 1.7e-51 175.0 12.9 1.7e-51 175.0 9.0 2.2 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EEB09319.1 - 8.8e-37 126.2 0.4 2.3e-36 124.9 0.3 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EEB09319.1 - 1.1e-23 82.9 0.1 1.1e-23 82.9 0.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain P16-Arc PF04699.9 EEB09319.1 - 0.0061 16.5 9.5 0.12 12.3 0.1 3.4 2 1 0 3 3 3 2 ARP2/3 complex 16 kDa subunit (p16-Arc) HTH_22 PF13309.1 EEB09319.1 - 0.11 12.3 3.5 2.3 8.0 0.0 3.9 4 0 0 4 4 4 0 HTH domain ING PF12998.2 EEB09319.1 - 0.34 11.2 9.1 1.7 8.9 0.5 3.6 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Exo_endo_phos PF03372.18 EEB09320.1 - 5e-27 95.4 0.1 6.7e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Apc13p PF05839.6 EEB09321.1 - 2.3e-17 62.7 0.3 4.1e-17 61.9 0.2 1.4 1 0 0 1 1 1 1 Apc13p protein Parathyroid PF01279.12 EEB09321.1 - 0.29 11.7 2.3 0.37 11.4 0.9 1.7 2 0 0 2 2 2 0 Parathyroid hormone family KH_1 PF00013.24 EEB09322.1 - 4.9e-05 22.8 0.0 0.057 13.0 0.0 4.2 5 0 0 5 5 5 2 KH domain KH_3 PF13014.1 EEB09322.1 - 0.00027 20.5 0.0 0.56 9.9 0.0 3.6 3 0 0 3 3 3 2 KH domain RhoGAP PF00620.22 EEB09323.1 - 2.6e-43 147.2 0.0 5.8e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEB09323.1 - 3.2e-16 59.1 18.8 5.8e-08 32.6 3.8 2.5 2 0 0 2 2 2 2 LIM domain Mst1_SARAH PF11629.3 EEB09323.1 - 0.058 13.2 0.6 0.23 11.2 0.3 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF972 PF06156.8 EEB09323.1 - 0.083 13.2 1.2 0.31 11.4 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EEB09323.1 - 0.096 12.9 0.4 0.26 11.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) RRM_1 PF00076.17 EEB09325.1 - 5.1e-08 32.4 0.2 0.018 14.6 0.0 3.7 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09325.1 - 3e-07 30.3 0.1 1.3e-05 25.0 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09325.1 - 0.00074 19.3 0.1 0.011 15.5 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI-anchored PF10342.4 EEB09326.1 - 1.2e-11 44.8 10.4 1.2e-11 44.8 7.2 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.12 EEB09326.1 - 0.0096 15.6 7.3 0.063 13.0 4.5 2.4 1 1 0 1 1 1 1 Tissue factor DUF4448 PF14610.1 EEB09326.1 - 0.45 9.9 6.4 0.84 9.0 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Macoilin PF09726.4 EEB09326.1 - 3.9 5.6 34.7 5.7 5.0 24.1 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 EEB09326.1 - 4.9 6.5 37.8 7.3 6.0 26.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribonuclease_3 PF00636.21 EEB09327.1 - 2.2e-21 76.3 0.2 2.5e-20 72.9 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEB09327.1 - 1.8e-18 66.7 0.2 1.8e-18 66.7 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 EEB09327.1 - 2.7e-08 34.2 0.0 6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif POX PF07526.6 EEB09327.1 - 0.25 11.5 2.6 0.45 10.7 1.3 1.7 1 1 0 1 1 1 0 Associated with HOX GRAB PF10375.4 EEB09328.1 - 2.1e-07 30.3 0.1 4.9e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain DUF724 PF05266.9 EEB09328.1 - 0.0047 16.5 10.6 0.0047 16.5 7.3 4.2 1 1 3 4 4 4 1 Protein of unknown function (DUF724) Pox_A_type_inc PF04508.7 EEB09328.1 - 0.0087 15.7 10.1 0.2 11.5 0.2 5.1 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Filament PF00038.16 EEB09328.1 - 0.077 12.4 49.4 0.15 11.5 6.9 3.0 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.7 EEB09328.1 - 0.11 12.2 25.5 0.064 13.0 4.0 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EEB09328.1 - 0.72 9.6 15.8 0.3 10.9 2.5 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF479 PF04336.7 EEB09328.1 - 0.76 9.9 6.3 0.26 11.3 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF479 TBPIP PF07106.8 EEB09328.1 - 2.6 7.5 46.5 0.089 12.3 2.5 4.2 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nop PF01798.13 EEB09329.1 - 4.2e-48 162.4 0.1 9.8e-48 161.2 0.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EEB09329.1 - 7.9e-42 142.6 0.3 7.9e-42 142.6 0.2 2.3 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 EEB09329.1 - 1.4e-15 56.8 0.1 3.4e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain Cwf_Cwc_15 PF04889.7 EEB09329.1 - 0.012 15.3 6.1 0.048 13.3 0.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FNIP_N PF14636.1 EEB09329.1 - 1.2 9.6 7.2 3.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus Rad52_Rad22 PF04098.10 EEB09330.1 - 1.7e-57 193.4 0.0 2.4e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3432 PF11914.3 EEB09330.1 - 0.36 10.8 14.4 0.68 9.9 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) MAP65_ASE1 PF03999.7 EEB09330.1 - 2.5 6.5 15.2 3.4 6.1 10.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ATP_bind_1 PF03029.12 EEB09331.1 - 1.9e-82 276.3 1.7 2.7e-82 275.9 0.1 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEB09331.1 - 2.8e-07 30.1 0.1 5.7e-06 25.8 0.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEB09331.1 - 2.2e-06 28.4 0.1 2.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EEB09331.1 - 1.5e-05 24.4 0.1 6.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Arf PF00025.16 EEB09331.1 - 2.2e-05 23.7 0.0 0.052 12.7 0.0 3.3 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EEB09331.1 - 3.4e-05 24.0 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEB09331.1 - 5.6e-05 22.7 3.1 0.00071 19.0 2.0 2.1 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EEB09331.1 - 7.4e-05 21.6 0.3 0.28 9.9 0.3 2.5 2 1 0 2 2 2 2 ArgK protein SRP54 PF00448.17 EEB09331.1 - 7.7e-05 22.2 0.0 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.14 EEB09331.1 - 0.00011 21.6 0.0 0.24 10.8 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EEB09331.1 - 0.00012 20.9 2.9 0.0042 15.8 0.0 3.1 2 1 1 3 3 3 1 G-protein alpha subunit AAA_16 PF13191.1 EEB09331.1 - 0.00012 22.0 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.17 EEB09331.1 - 0.00024 20.5 0.0 0.054 12.8 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_23 PF13476.1 EEB09331.1 - 0.00033 21.0 3.9 0.019 15.2 0.4 2.4 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EEB09331.1 - 0.00045 20.7 0.1 0.3 11.5 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein NACHT PF05729.7 EEB09331.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 EEB09331.1 - 0.00075 19.3 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEB09331.1 - 0.001 18.5 0.1 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family FeoB_N PF02421.13 EEB09331.1 - 0.0011 18.3 0.0 0.05 12.8 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B NB-ARC PF00931.17 EEB09331.1 - 0.0018 17.1 0.5 0.0035 16.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EEB09331.1 - 0.0031 17.2 0.0 0.0087 15.7 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EEB09331.1 - 0.004 16.7 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEB09331.1 - 0.0042 17.4 5.7 0.0062 16.8 0.0 3.0 2 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EEB09331.1 - 0.0064 16.4 0.0 0.024 14.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EEB09331.1 - 0.0072 15.3 0.4 0.06 12.3 0.3 2.0 1 1 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.7 EEB09331.1 - 0.0074 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EEB09331.1 - 0.0074 16.1 0.2 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EEB09331.1 - 0.01 15.3 0.1 0.12 11.8 0.0 2.6 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 EEB09331.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 EEB09331.1 - 0.013 15.2 0.5 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase APS_kinase PF01583.15 EEB09331.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SE PF00437.15 EEB09331.1 - 0.021 13.7 0.0 0.061 12.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EEB09331.1 - 0.022 14.4 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 NTPase KTI12 PF08433.5 EEB09331.1 - 0.025 13.8 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 EEB09331.1 - 0.037 13.0 1.0 0.16 10.9 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EEB09331.1 - 0.038 13.3 1.2 0.19 11.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EEB09331.1 - 0.05 12.9 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.17 EEB09331.1 - 0.056 13.6 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EEB09331.1 - 0.057 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EEB09331.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EEB09331.1 - 0.082 12.1 0.8 0.35 10.0 0.0 2.3 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit GrpE PF01025.14 EEB09331.1 - 0.79 9.2 10.7 3.2 7.2 5.6 2.2 1 1 1 2 2 2 0 GrpE Dynamin_N PF00350.18 EEB09331.1 - 1.4 8.6 9.7 0.42 10.4 0.2 3.6 1 1 1 2 2 2 0 Dynamin family DUF2347 PF09804.4 EEB09332.2 - 1.2e-47 162.5 0.1 7e-45 153.4 0.1 3.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EEB09332.2 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis M16C_assoc PF08367.6 EEB09333.1 - 3e-65 219.5 1.0 4.6e-65 218.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EEB09333.1 - 1.1e-34 119.7 0.5 4.1e-23 82.0 0.0 3.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEB09333.1 - 3.7e-05 23.5 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SBP_bac_7 PF03480.8 EEB09333.1 - 0.33 10.0 4.2 0.43 9.6 0.5 2.6 3 0 0 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 Ribosomal_L38e PF01781.13 EEB09334.2 - 2.7e-33 113.5 1.7 3e-33 113.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.1 EEB09335.1 - 3.4e-20 72.6 0.0 4.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEB09335.1 - 9.5e-10 38.5 0.0 2.5e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB09335.1 - 3.2e-05 23.8 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEB09335.1 - 0.0011 18.6 0.0 0.0024 17.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EEB09335.1 - 0.024 14.5 0.2 0.077 12.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FimP PF09766.4 EEB09336.1 - 5.1e-16 58.6 13.0 6.5e-16 58.3 9.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein IL34 PF15036.1 EEB09336.1 - 0.0031 17.1 1.0 0.0048 16.4 0.2 1.6 2 0 0 2 2 2 1 Interleukin 34 Acetyltransf_11 PF13720.1 EEB09336.1 - 0.13 12.5 2.6 10 6.4 0.3 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1664 PF07889.7 EEB09336.1 - 0.34 10.7 4.1 12 5.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IFP_35_N PF07334.8 EEB09336.1 - 0.43 10.5 10.9 0.54 10.2 0.1 3.9 2 2 3 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF972 PF06156.8 EEB09336.1 - 3.4 8.0 11.1 1.9 8.8 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_27 PF13514.1 EEB09337.1 - 0.0034 15.1 5.3 0.0037 15.0 3.7 1.0 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EEB09337.1 - 0.0064 16.0 10.1 0.0076 15.7 7.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Prominin PF05478.6 EEB09337.1 - 0.0091 13.5 5.5 0.011 13.3 3.8 1.0 1 0 0 1 1 1 1 Prominin Muted PF14942.1 EEB09337.1 - 0.017 15.0 9.9 0.022 14.6 6.9 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF2130 PF09903.4 EEB09337.1 - 0.052 12.2 8.6 0.067 11.9 5.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Rho_Binding PF08912.6 EEB09337.1 - 0.053 13.8 11.0 1.9 8.8 4.6 2.2 2 0 0 2 2 2 0 Rho Binding Herpes_UL6 PF01763.11 EEB09337.1 - 0.053 11.7 4.3 0.058 11.5 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Lectin_N PF03954.9 EEB09337.1 - 0.089 12.1 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF812 PF05667.6 EEB09337.1 - 0.093 11.2 9.0 0.11 10.9 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Trypan_glycop PF00913.14 EEB09337.1 - 0.15 10.9 2.3 0.17 10.7 1.6 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF4085 PF13315.1 EEB09337.1 - 0.17 11.2 4.9 0.2 10.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Borrelia_REV PF03978.8 EEB09337.1 - 0.19 11.4 6.6 0.24 11.1 4.6 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Apolipoprotein PF01442.13 EEB09337.1 - 0.21 11.0 10.1 0.91 9.0 7.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.8 EEB09337.1 - 0.23 11.9 12.9 0.79 10.2 0.2 2.6 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Baculo_PEP_C PF04513.7 EEB09337.1 - 0.23 11.2 1.4 0.38 10.5 1.0 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EEB09337.1 - 0.28 9.5 8.6 0.34 9.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PRTP PF01366.13 EEB09337.1 - 0.33 8.9 5.7 0.39 8.6 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Sipho_Gp157 PF05565.6 EEB09337.1 - 0.34 10.4 9.7 0.5 9.9 6.7 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 HD_3 PF13023.1 EEB09337.1 - 0.42 10.3 5.0 0.51 10.0 3.4 1.1 1 0 0 1 1 1 0 HD domain Allexi_40kDa PF05549.6 EEB09337.1 - 0.43 9.8 4.1 0.5 9.6 2.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Bot1p PF12298.3 EEB09337.1 - 0.44 10.4 7.3 7.5 6.4 1.6 2.2 1 1 1 2 2 2 0 Eukaryotic mitochondrial regulator protein NinG PF05766.7 EEB09337.1 - 0.5 10.0 6.8 0.039 13.6 1.6 1.4 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4301 PF14134.1 EEB09337.1 - 0.7 8.3 5.6 1.3 7.5 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4301) Tho2 PF11262.3 EEB09337.1 - 0.73 8.8 7.6 0.35 9.8 3.2 1.6 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 FliT PF05400.8 EEB09337.1 - 0.86 10.0 10.0 9.7 6.6 7.0 2.4 1 1 0 1 1 1 0 Flagellar protein FliT KLRAQ PF10205.4 EEB09337.1 - 0.87 9.6 10.4 2.1 8.4 7.1 1.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein PMSI1 PF15322.1 EEB09337.1 - 1 8.3 4.2 1.2 8.1 2.9 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative AAA_13 PF13166.1 EEB09337.1 - 1.1 7.6 10.0 1.3 7.4 6.9 1.0 1 0 0 1 1 1 0 AAA domain DUF1515 PF07439.6 EEB09337.1 - 1.2 8.9 5.9 3 7.6 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Adeno_PIX PF03955.9 EEB09337.1 - 1.4 9.4 3.8 1.1 9.8 1.4 1.6 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Enkurin PF13864.1 EEB09337.1 - 1.4 9.1 11.4 2.2 8.5 7.9 1.4 1 0 0 1 1 1 0 Calmodulin-binding Thymidylate_kin PF02223.12 EEB09337.1 - 2.1 7.7 7.6 0.71 9.2 3.3 1.6 1 1 1 2 2 2 0 Thymidylate kinase GvpL_GvpF PF06386.6 EEB09337.1 - 2.8 7.4 7.7 3.2 7.2 4.3 1.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ApoC-I PF04691.7 EEB09337.1 - 4 7.1 10.1 9.5 6.0 2.0 2.8 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) Histone_HNS PF00816.16 EEB09337.1 - 7.4 7.1 10.5 9.2 6.8 0.2 2.5 1 1 1 2 2 2 0 H-NS histone family PI3_PI4_kinase PF00454.22 EEB09338.1 - 1.6e-39 135.8 0.0 8.2e-39 133.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEB09338.1 - 1.3e-18 66.8 0.4 4.2e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UCH PF00443.24 EEB09339.1 - 1.2e-29 103.2 0.3 2e-29 102.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEB09339.1 - 1.1e-10 41.4 2.9 1.2e-10 41.2 0.6 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein PITH PF06201.8 EEB09340.2 - 8.8e-42 142.4 0.1 1.3e-41 141.8 0.1 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EEB09340.2 - 4.6e-25 87.2 0.1 8.6e-25 86.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEB09340.2 - 3.6e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EEB09340.2 - 2.3e-05 24.5 0.1 8.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EEB09340.2 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EEB09340.2 - 0.00034 20.5 0.3 0.00073 19.5 0.2 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EEB09340.2 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 EEB09340.2 - 0.11 12.0 0.1 0.41 10.0 0.0 1.8 1 1 1 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.6 EEB09340.2 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE WD40 PF00400.27 EEB09341.1 - 8.2e-34 114.2 21.0 2.1e-10 40.0 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEB09341.1 - 0.00065 19.4 0.0 0.019 14.7 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Proteasome PF00227.21 EEB09342.1 - 1.9e-22 79.4 0.0 2.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 EEB09342.1 - 0.078 12.5 0.0 0.94 9.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain DUF3074 PF11274.3 EEB09343.1 - 2.3e-23 82.7 0.2 3.9e-23 82.0 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DUF2359 PF10151.4 EEB09343.1 - 0.11 10.9 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) ATP_bind_4 PF01902.12 EEB09344.1 - 3.1e-45 154.2 0.0 6.6e-45 153.1 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EEB09344.1 - 5.7e-19 68.0 0.1 1.5e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP QueC PF06508.8 EEB09344.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EEB09344.1 - 0.071 12.5 0.1 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Syja_N PF02383.13 EEB09345.1 - 9.3e-41 139.6 0.4 1.9e-40 138.6 0.3 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EEB09345.1 - 9e-21 74.9 0.0 1.9e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EEB09345.1 - 0.01 15.4 0.1 0.027 14.0 0.1 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ODC_AZ PF02100.12 EEB09346.1 - 8.6e-24 83.1 0.0 1.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme SHNi-TPR PF10516.4 EEB09347.1 - 2.4e-15 55.4 3.5 5.7e-15 54.2 1.4 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EEB09347.1 - 4.6e-07 29.3 4.5 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EEB09347.1 - 0.0061 16.4 6.4 0.27 11.2 0.1 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat H-kinase_dim PF02895.9 EEB09347.1 - 0.027 14.8 2.8 0.081 13.2 0.8 2.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain TPR_2 PF07719.12 EEB09347.1 - 0.048 13.5 10.3 1 9.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEB09347.1 - 0.056 14.1 8.1 2.4 8.9 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEB09347.1 - 0.13 12.2 2.8 28 4.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Utp12 PF04003.7 EEB09347.1 - 0.19 11.6 2.1 1.8 8.5 1.5 2.3 1 1 0 1 1 1 0 Dip2/Utp12 Family Syntaxin PF00804.20 EEB09347.1 - 0.2 11.8 3.5 0.13 12.4 0.5 2.1 2 0 0 2 2 2 0 Syntaxin TPR_1 PF00515.23 EEB09347.1 - 0.53 9.9 4.1 21 4.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 EEB09348.1 - 1.8e-50 171.4 0.2 2.8e-50 170.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AsnA PF03590.10 EEB09348.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase Macoilin PF09726.4 EEB09348.1 - 6.5 4.8 10.4 9 4.4 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Asn_synthase PF00733.16 EEB09349.1 - 1.6e-71 240.8 0.0 2.2e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEB09349.1 - 7.3e-40 135.5 0.0 1.2e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEB09349.1 - 6.7e-32 110.2 0.0 2.2e-31 108.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEB09349.1 - 7.6e-09 35.1 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EEB09349.1 - 0.0012 17.6 0.0 0.26 9.9 0.0 2.8 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EEB09349.1 - 0.035 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD synthase ORMDL PF04061.9 EEB09350.1 - 1.5e-58 196.1 8.9 1.8e-58 195.9 6.2 1.1 1 0 0 1 1 1 1 ORMDL family DUF1211 PF06736.6 EEB09350.1 - 0.46 10.6 3.6 5.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Pkinase PF00069.20 EEB09351.1 - 3.8e-60 203.2 0.0 4.3e-52 176.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09351.1 - 1.1e-26 93.4 0.0 8.9e-20 70.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEB09351.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EEB09351.1 - 0.16 11.0 0.1 0.58 9.1 0.0 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEB09352.1 - 8.1e-29 100.5 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EEB09352.1 - 1.6e-11 43.2 10.6 0.0036 17.2 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat Pkinase_Tyr PF07714.12 EEB09352.1 - 1.2e-10 40.9 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EEB09352.1 - 9.7e-08 32.2 1.4 0.035 14.3 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EEB09352.1 - 0.068 13.6 2.3 22 5.7 0.1 4.5 4 0 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEB09352.1 - 0.14 12.5 0.2 0.58 10.5 0.2 2.1 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region SCO1-SenC PF02630.9 EEB09353.1 - 5.1e-53 179.2 0.0 7.1e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EEB09353.1 - 3.1e-05 23.6 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EEB09353.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like SH3_9 PF14604.1 EEB09354.1 - 1.2e-15 56.7 0.0 1.8e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEB09354.1 - 2.2e-15 55.7 0.0 2.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEB09354.1 - 2.7e-12 45.9 0.0 3.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain YppG PF14179.1 EEB09354.1 - 1.9 9.1 14.2 46 4.6 9.0 2.1 2 0 0 2 2 2 0 YppG-like protein Mit_KHE1 PF10173.4 EEB09357.1 - 0.3 10.9 3.4 9.8 5.9 1.5 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related APG6 PF04111.7 EEB09357.1 - 1.1 8.3 17.3 2.1 7.3 12.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 IKKbetaNEMObind PF12179.3 EEB09357.1 - 3.5 7.5 9.6 3.2 7.6 0.1 4.0 3 2 1 4 4 4 0 I-kappa-kinase-beta NEMO binding domain Peptidase_S46 PF10459.4 EEB09357.1 - 8 4.7 8.3 11 4.2 5.7 1.1 1 0 0 1 1 1 0 Peptidase S46 RPAP1_C PF08620.5 EEB09358.1 - 1.6e-29 101.5 0.0 3.9e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EEB09358.1 - 7e-11 41.5 4.5 7e-11 41.5 3.1 2.0 1 1 1 2 2 2 1 RPAP1-like, N-terminal HEAT PF02985.17 EEB09358.1 - 0.022 14.8 0.3 12 6.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat VHS PF00790.14 EEB09359.1 - 0.082 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 VHS domain HUN PF08729.5 EEB09360.1 - 3.4e-13 49.2 0.1 7.1e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Sds3 PF08598.6 EEB09360.1 - 0.017 14.6 1.2 0.023 14.2 0.9 1.2 1 0 0 1 1 1 0 Sds3-like MDH PF02315.11 EEB09360.1 - 0.14 12.1 0.5 0.31 10.9 0.3 1.6 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit SURF6 PF04935.7 EEB09361.1 - 6.9e-41 139.8 53.1 1e-40 139.3 36.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 6 NIF3 PF01784.13 EEB09362.1 - 5.9e-66 222.4 0.0 7.2e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Adaptin_N PF01602.15 EEB09363.1 - 1.1e-136 456.2 17.2 1.3e-136 456.0 11.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEB09363.1 - 1.1e-19 71.0 10.3 5.9e-19 68.5 0.8 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEB09363.1 - 1.7e-17 63.4 2.4 1.3e-07 31.8 0.1 5.3 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EEB09363.1 - 1.8e-07 30.6 8.9 0.047 13.7 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EEB09363.1 - 5e-05 23.6 1.4 0.21 12.1 0.0 4.6 3 0 0 3 3 3 1 HEAT-like repeat DUF1959 PF09218.5 EEB09363.1 - 0.015 15.0 0.4 0.059 13.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) AAA PF00004.24 EEB09364.2 - 2.4e-38 131.3 0.0 3.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEB09364.2 - 1.3e-08 34.6 0.0 1.9e-06 27.6 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EEB09364.2 - 2.6e-07 30.8 0.1 3.5e-05 23.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEB09364.2 - 4e-06 26.0 0.0 6.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEB09364.2 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EEB09364.2 - 0.00019 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEB09364.2 - 0.00041 19.8 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEB09364.2 - 0.00072 18.3 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EEB09364.2 - 0.00092 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEB09364.2 - 0.001 18.8 0.1 0.0026 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEB09364.2 - 0.0014 18.6 0.1 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EEB09364.2 - 0.0021 17.8 0.0 1.9 8.1 0.0 2.2 1 1 1 2 2 2 2 Archaeal ATPase Mg_chelatase PF01078.16 EEB09364.2 - 0.0024 17.0 0.1 0.0048 16.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EEB09364.2 - 0.0034 18.1 0.0 0.0067 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEB09364.2 - 0.0036 17.0 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 EEB09364.2 - 0.0069 15.8 0.3 0.13 11.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EEB09364.2 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB09364.2 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EEB09364.2 - 0.022 14.4 0.1 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.1 EEB09364.2 - 0.026 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEB09364.2 - 0.034 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 EEB09364.2 - 0.075 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 EEB09364.2 - 0.085 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EEB09364.2 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EEB09364.2 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEB09364.2 - 0.19 10.7 0.0 0.41 9.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EEB09364.2 - 0.21 10.5 0.1 0.63 8.9 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EEB09364.2 - 0.24 10.4 0.4 4.2 6.4 0.1 2.1 1 1 1 2 2 2 0 KaiC HSP20 PF00011.16 EEB09365.1 - 2.8e-24 84.9 0.5 3.5e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EEB09365.1 - 0.00031 20.3 0.2 0.00044 19.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) CS PF04969.11 EEB09365.1 - 0.0023 18.4 0.1 0.0057 17.1 0.1 1.7 1 1 0 1 1 1 1 CS domain BON PF04972.12 EEB09365.1 - 0.016 14.9 0.4 0.048 13.4 0.2 1.9 2 0 0 2 2 2 0 BON domain HMA PF00403.21 EEB09365.1 - 0.11 12.6 1.8 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain polyprenyl_synt PF00348.12 EEB09366.1 - 6.1e-50 169.4 0.0 3.7e-49 166.9 0.0 1.9 2 0 0 2 2 2 1 Polyprenyl synthetase Coatomer_WDAD PF04053.9 EEB09367.1 - 3.6e-127 424.8 6.3 6.5e-127 423.9 4.1 1.7 1 1 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EEB09367.1 - 2.2e-76 257.1 1.0 3.3e-76 256.5 0.7 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EEB09367.1 - 6.9e-58 190.5 16.0 1.4e-11 43.8 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEB09367.1 - 0.00029 19.1 8.1 0.094 10.8 0.1 3.8 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Far-17a_AIG1 PF04750.9 EEB09368.2 - 1e-38 132.5 16.2 1.2e-38 132.3 11.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4234 PF14018.1 EEB09368.2 - 0.05 13.3 0.3 0.05 13.3 0.2 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF4234) UDP-g_GGTase PF06427.6 EEB09369.1 - 1.6e-56 190.9 0.6 4e-56 189.6 0.4 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EEB09369.1 - 1.1e-07 31.5 0.7 2.4e-07 30.3 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpn3_C PF08375.6 EEB09370.1 - 1.7e-24 85.9 0.4 4.9e-24 84.5 0.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EEB09370.1 - 2.5e-19 69.5 0.1 3.1e-18 66.0 0.0 2.7 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EEB09370.1 - 0.0046 16.7 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 UQ_con PF00179.21 EEB09371.1 - 4.1e-52 175.3 0.0 4.6e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEB09371.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEB09371.1 - 0.0032 17.3 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEB09371.1 - 0.042 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain SET PF00856.23 EEB09372.2 - 1.5e-24 87.1 3.1 2.9e-23 82.9 0.3 2.9 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.11 EEB09372.2 - 8.1e-23 80.6 3.3 8.1e-23 80.6 2.3 2.0 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 EEB09372.2 - 2e-11 43.3 1.5 2.2e-11 43.2 0.1 1.8 1 1 1 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PH_6 PF15406.1 EEB09373.1 - 3e-36 123.8 1.8 7.4e-36 122.6 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EEB09373.1 - 0.0054 16.9 0.3 0.03 14.5 0.0 2.6 2 1 0 2 2 2 1 PH domain Telomerase_RBD PF12009.3 EEB09373.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain RXT2_N PF08595.6 EEB09374.1 - 5.1e-18 65.3 4.8 3e-16 59.5 1.2 2.7 2 1 0 2 2 2 1 RXT2-like, N-terminal Arginosuc_synth PF00764.14 EEB09375.1 - 5e-151 503.1 0.0 5.7e-151 502.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EEB09375.1 - 0.0031 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EEB09375.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EEB09375.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Apq12 PF12716.2 EEB09376.1 - 6.5e-11 41.7 13.5 9.5e-11 41.2 9.4 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF1240 PF06836.7 EEB09376.1 - 0.14 12.4 4.9 0.18 12.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) Hydrolase_3 PF08282.7 EEB09377.1 - 1.1e-47 162.7 0.0 1.2e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEB09377.1 - 1.3e-08 34.4 0.0 0.00099 18.4 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EEB09377.1 - 0.01 16.2 0.9 0.38 11.1 0.6 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEB09377.1 - 0.018 15.2 0.0 0.54 10.3 0.0 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DIOX_N PF14226.1 EEB09378.1 - 6e-26 91.2 0.0 2.7e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEB09378.1 - 1.5e-19 70.1 0.0 2.7e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CENP-O PF09496.5 EEB09379.1 - 9.9e-15 54.5 0.2 3.7e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component MAAL_N PF05034.8 EEB09379.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus DUF904 PF06005.7 EEB09379.1 - 0.17 12.1 1.6 0.34 11.2 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TYW3 PF02676.9 EEB09380.1 - 5.8e-54 182.3 0.0 6.7e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 POP1 PF06978.6 EEB09381.1 - 1.4e-54 184.5 9.6 2.6e-54 183.7 6.7 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EEB09381.1 - 8.3e-31 105.6 0.2 1.9e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 EEB09381.1 - 3.4e-05 23.3 0.0 0.12 11.7 0.0 2.7 2 1 0 3 3 3 2 Aminomethyltransferase folate-binding domain RVT_N PF13655.1 EEB09381.1 - 0.072 13.1 0.3 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase Peptidase_A22B PF04258.8 EEB09382.1 - 1.2e-63 215.3 8.1 6.9e-58 196.4 2.2 2.0 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 EEB09382.1 - 0.0014 17.8 18.0 0.076 12.1 12.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) DUF2393 PF09624.5 EEB09382.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) zf-H2C2_2 PF13465.1 EEB09383.1 - 6.1e-08 32.5 11.1 5.7e-06 26.3 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEB09383.1 - 6.8e-08 32.4 11.9 0.00015 21.8 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEB09383.1 - 0.00045 20.3 8.8 0.0042 17.3 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EEB09383.1 - 1.4 9.3 7.9 3 8.2 0.9 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain RRM_3 PF08777.6 EEB09384.1 - 2.1e-05 24.3 0.1 8.1e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 RNA binding motif CPSF73-100_C PF11718.3 EEB09385.2 - 2.8e-58 196.8 4.9 2.8e-58 196.8 3.4 1.8 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EEB09385.2 - 1.5e-35 121.9 0.1 1.8e-34 118.4 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EEB09385.2 - 2.1e-15 56.8 0.5 3.6e-15 56.1 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEB09385.2 - 2.5e-11 43.4 0.2 5.8e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EEB09385.2 - 1.1e-09 37.9 0.1 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EEB09385.2 - 4.3e-07 29.7 0.1 1.9e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Mtc PF03820.12 EEB09386.1 - 3.4e-118 393.7 0.0 3.8e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DEAD PF00270.24 EEB09387.1 - 6.9e-35 120.0 0.1 1.2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09387.1 - 2.5e-27 94.5 0.0 2.3e-26 91.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB09387.1 - 5.5e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEB09387.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF4243 PF14027.1 EEB09388.1 - 0.015 14.7 6.8 0.047 13.1 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4243) DUF3573 PF12097.3 EEB09388.1 - 5.1 5.6 4.5 4.9 5.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) ApbA PF02558.11 EEB09389.2 - 2.8e-08 33.3 0.0 4.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEB09389.2 - 0.0038 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal COPIIcoated_ERV PF07970.7 EEB09390.1 - 4.8e-66 222.5 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEB09390.1 - 3.6e-34 116.6 0.8 7.7e-34 115.5 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MPC PF03650.8 EEB09391.1 - 9.2e-46 154.6 0.5 1e-45 154.5 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 EEB09391.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Sel1 PF08238.7 EEB09392.1 - 2.3e-45 151.9 15.2 1.4e-09 38.2 0.9 8.0 8 0 0 8 8 8 6 Sel1 repeat YL1 PF05764.8 EEB09393.1 - 1e-33 116.9 29.8 1.2e-33 116.7 20.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EEB09393.1 - 4.5e-09 35.7 0.1 8.7e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Mem_trans PF03547.13 EEB09393.1 - 0.012 13.9 0.2 0.015 13.6 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Pkinase PF00069.20 EEB09394.1 - 6.5e-61 205.7 0.1 4.6e-60 202.9 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09394.1 - 1.6e-29 102.7 0.1 1.1e-21 77.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EEB09394.1 - 1e-05 25.9 0.3 2.1e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEB09394.1 - 7.3e-05 21.8 0.4 0.00084 18.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEB09394.1 - 0.00078 19.2 2.9 0.25 11.0 0.1 3.0 1 1 2 3 3 3 2 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 EEB09395.1 - 7.5e-43 146.3 1.8 8.7e-43 146.1 1.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DELLA PF12041.3 EEB09395.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Lge1 PF11488.3 EEB09395.1 - 0.059 13.5 0.8 0.12 12.6 0.6 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF3373 PF11853.3 EEB09395.1 - 0.08 11.4 1.9 0.11 10.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DivIC PF04977.10 EEB09395.1 - 0.22 11.0 2.6 0.43 10.0 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DNA_pol3_a_NII PF11490.3 EEB09395.1 - 0.44 10.1 4.1 0.89 9.1 1.6 2.3 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Sugarporin_N PF11471.3 EEB09395.1 - 1.1 8.9 4.4 0.34 10.5 0.9 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AAA PF00004.24 EEB09396.2 - 8.2e-92 304.3 0.1 3e-45 153.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEB09396.2 - 3.5e-15 55.6 0.0 4.9e-08 32.2 0.0 2.6 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEB09396.2 - 5e-13 49.9 0.1 2.5e-07 31.5 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EEB09396.2 - 5.9e-13 49.0 0.1 0.00055 20.0 0.0 5.0 2 2 1 3 3 2 2 AAA domain AAA_16 PF13191.1 EEB09396.2 - 1.8e-12 47.5 2.3 0.00013 22.0 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 EEB09396.2 - 8.7e-12 45.1 0.0 1.2e-05 25.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEB09396.2 - 6.2e-11 42.2 0.0 0.00028 20.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEB09396.2 - 6.6e-11 42.1 0.2 0.00046 19.9 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEB09396.2 - 9.8e-11 41.8 0.0 0.00016 21.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEB09396.2 - 3.4e-10 40.3 0.0 7.1e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EEB09396.2 - 5.8e-10 38.6 0.0 0.0016 17.5 0.0 3.0 3 0 0 3 3 2 2 Zeta toxin RNA_helicase PF00910.17 EEB09396.2 - 7.7e-09 35.6 0.0 0.0014 18.7 0.0 3.4 3 1 0 3 3 2 2 RNA helicase TIP49 PF06068.8 EEB09396.2 - 1.1e-08 34.2 2.3 6.3e-05 21.8 0.0 3.3 4 0 0 4 4 4 2 TIP49 C-terminus IstB_IS21 PF01695.12 EEB09396.2 - 4.7e-08 32.6 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EEB09396.2 - 5.9e-08 32.8 0.0 0.0016 18.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEB09396.2 - 9e-08 31.7 0.1 0.017 14.8 0.0 3.4 2 1 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EEB09396.2 - 1.3e-07 31.3 0.2 0.0052 16.4 0.0 3.4 2 1 1 3 3 3 2 NACHT domain Mg_chelatase PF01078.16 EEB09396.2 - 1.5e-07 30.7 0.5 0.0073 15.4 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEB09396.2 - 4.6e-07 29.5 0.0 0.0015 18.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEB09396.2 - 7.7e-07 28.9 0.2 8.1e-05 22.4 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 EEB09396.2 - 1.3e-06 27.9 9.2 0.22 10.9 0.0 5.2 3 2 2 5 5 5 2 AAA domain Cytidylate_kin2 PF13189.1 EEB09396.2 - 1.6e-06 28.1 0.0 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 EEB09396.2 - 5e-06 26.4 0.3 0.031 14.1 0.0 3.4 4 0 0 4 4 2 2 Shikimate kinase ABC_tran PF00005.22 EEB09396.2 - 6.3e-06 26.5 0.0 0.24 11.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.8 EEB09396.2 - 7.7e-06 25.0 0.0 0.051 12.4 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) KaiC PF06745.8 EEB09396.2 - 2.1e-05 23.7 0.0 0.42 9.6 0.0 3.4 2 1 0 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 EEB09396.2 - 2.3e-05 24.4 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EEB09396.2 - 6.9e-05 22.4 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EEB09396.2 - 7.3e-05 22.3 0.0 0.21 11.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEB09396.2 - 9e-05 22.2 0.0 0.81 9.3 0.0 3.3 2 1 1 3 3 3 2 Archaeal ATPase Rad17 PF03215.10 EEB09396.2 - 0.0001 21.1 0.1 0.032 12.9 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EEB09396.2 - 0.00012 21.0 0.0 0.31 9.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 EEB09396.2 - 0.00015 21.3 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EEB09396.2 - 0.00042 19.2 0.1 0.57 8.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 EEB09396.2 - 0.00064 19.0 0.1 1.3 8.1 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 EEB09396.2 - 0.00072 19.1 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EEB09396.2 - 0.0019 17.8 0.0 2 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEB09396.2 - 0.0022 17.5 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EEB09396.2 - 0.0029 17.4 0.0 4.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EEB09396.2 - 0.0031 17.2 0.0 1.7 8.3 0.0 3.1 2 1 1 3 3 3 1 NTPase AFG1_ATPase PF03969.11 EEB09396.2 - 0.0048 15.7 0.0 0.71 8.6 0.0 2.6 2 0 0 2 2 2 1 AFG1-like ATPase SRPRB PF09439.5 EEB09396.2 - 0.0091 15.2 0.0 2.2 7.4 0.0 3.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit CPT PF07931.7 EEB09396.2 - 0.011 15.4 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EEB09396.2 - 0.013 14.9 0.1 4.4 6.6 0.0 3.2 2 2 0 2 2 2 0 AAA-like domain Bac_DnaA PF00308.13 EEB09396.2 - 0.02 14.5 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein MMR_HSR1 PF01926.18 EEB09396.2 - 0.021 14.7 0.0 9.2 6.2 0.0 3.8 2 2 1 3 3 3 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEB09396.2 - 0.025 14.0 0.0 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 EEB09396.2 - 0.025 13.5 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 EEB09396.2 - 0.027 13.6 0.1 2.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Guanylate_kin PF00625.16 EEB09396.2 - 0.058 12.8 0.0 6.8 6.0 0.0 3.3 2 1 1 3 3 3 0 Guanylate kinase ADK PF00406.17 EEB09396.2 - 0.068 13.0 0.1 8.4 6.2 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase HECT PF00632.20 EEB09397.1 - 5.7e-95 318.1 0.0 7.9e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEB09397.1 - 1.3e-34 117.6 18.9 1.1e-11 44.2 1.2 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EEB09397.1 - 1.7e-15 56.6 0.0 4.1e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EEB09398.1 - 9e-17 60.4 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09398.1 - 5.7e-15 55.0 0.0 1.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09398.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 EEB09398.1 - 0.0059 16.0 7.7 0.0086 15.5 5.3 1.2 1 0 0 1 1 1 1 Septum formation initiator CASP_C PF08172.7 EEB09398.1 - 0.0075 15.3 0.3 0.0097 14.9 0.2 1.1 1 0 0 1 1 1 1 CASP C terminal GAS PF13851.1 EEB09398.1 - 0.0078 15.4 2.4 0.0093 15.1 1.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EEB09398.1 - 0.021 13.8 4.2 0.026 13.5 2.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEB09398.1 - 0.022 14.3 2.6 0.027 14.0 1.8 1.1 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 EEB09398.1 - 0.032 14.4 4.4 0.05 13.7 3.0 1.2 1 0 0 1 1 1 0 Tup N-terminal NPV_P10 PF05531.7 EEB09398.1 - 0.033 14.4 2.6 0.12 12.6 1.8 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Striatin PF08232.7 EEB09398.1 - 0.051 13.8 1.1 0.068 13.4 0.8 1.1 1 0 0 1 1 1 0 Striatin family DUF4140 PF13600.1 EEB09398.1 - 0.058 13.8 2.1 0.09 13.2 1.4 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.6 EEB09398.1 - 0.062 12.7 3.5 0.072 12.5 2.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Frankia_peptide PF14407.1 EEB09398.1 - 0.11 12.2 3.7 5.9 6.7 0.8 2.3 1 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Prominin PF05478.6 EEB09398.1 - 0.12 9.8 0.2 0.15 9.6 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 EEB09398.1 - 0.13 12.6 1.2 0.15 12.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EEB09398.1 - 0.13 10.0 0.7 0.14 9.9 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EEB09398.1 - 0.28 10.7 3.9 0.41 10.1 2.7 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4337 PF14235.1 EEB09398.1 - 0.3 10.8 4.4 0.4 10.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_1 PF00170.16 EEB09398.1 - 0.66 9.9 7.1 1 9.3 5.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF2968 PF11180.3 EEB09398.1 - 0.99 8.7 8.1 1.3 8.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HALZ PF02183.13 EEB09398.1 - 5.1 6.8 7.7 5.7 6.7 3.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Coa1 PF08695.5 EEB09400.1 - 9.4e-27 92.8 0.1 1.6e-26 92.1 0.0 1.4 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Pex14_N PF04695.8 EEB09400.1 - 0.23 11.4 2.0 0.32 11.0 1.1 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CUE PF02845.11 EEB09401.2 - 9.2e-07 28.2 0.0 0.0028 17.0 0.0 2.4 2 0 0 2 2 2 2 CUE domain Hap4_Hap_bind PF10297.4 EEB09402.1 - 3.8e-07 29.7 5.1 3.8e-07 29.7 3.5 2.2 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 HALZ PF02183.13 EEB09402.1 - 0.052 13.2 2.0 0.19 11.4 1.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2762 PF10960.3 EEB09402.1 - 0.079 12.6 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) zf-FCS PF06467.9 EEB09402.1 - 0.16 11.6 2.5 4 7.1 0.1 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FMO-like PF00743.14 EEB09403.1 - 1.3e-35 122.6 0.0 9.6e-19 66.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEB09403.1 - 2.5e-21 76.6 0.0 5.9e-21 75.4 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEB09403.1 - 2.8e-14 53.1 0.0 7.5e-12 45.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEB09403.1 - 6.4e-08 31.8 1.8 2.4e-06 26.6 0.1 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEB09403.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEB09403.1 - 4.5e-07 29.9 0.0 2.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEB09403.1 - 3.2e-05 23.0 0.3 0.0017 17.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEB09403.1 - 8.1e-05 21.8 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EEB09403.1 - 0.00072 18.7 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EEB09403.1 - 0.015 13.7 0.0 0.019 13.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EEB09403.1 - 0.033 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EEB09403.1 - 0.077 13.1 0.0 6 6.9 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EEB09403.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Adap_comp_sub PF00928.16 EEB09404.1 - 1.6e-92 309.3 0.0 2.1e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEB09404.1 - 3.1e-06 26.9 0.6 5.6e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EEB09404.1 - 0.00027 19.6 0.0 0.00035 19.2 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RRM_6 PF14259.1 EEB09405.1 - 1.6e-05 24.7 0.1 8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB09405.1 - 9.1e-05 22.0 2.4 0.00012 21.6 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09405.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.1 EEB09406.1 - 5.8e-31 106.2 5.7 9.4e-16 57.8 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEB09406.1 - 8.4e-23 80.5 1.3 1.3e-12 47.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEB09406.1 - 1.3e-21 75.1 1.9 1.1e-11 43.9 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEB09406.1 - 2.7e-21 75.1 3.3 8.4e-13 48.1 0.4 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEB09406.1 - 1.6e-19 67.9 1.0 1.8e-08 33.8 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat UQ_con PF00179.21 EEB09407.1 - 1.8e-50 170.0 0.0 2e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAT PF02259.18 EEB09408.1 - 4.5e-67 226.5 10.0 9.9e-67 225.3 6.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EEB09408.1 - 1e-23 84.0 0.6 3.3e-23 82.3 0.4 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EEB09408.1 - 9.4e-09 34.5 0.6 9.4e-09 34.5 0.4 2.4 2 0 0 2 2 2 1 FATC domain TPR_2 PF07719.12 EEB09408.1 - 0.008 16.0 0.3 12 6.1 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEB09408.1 - 0.069 13.0 2.1 4.7 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1700 PF08006.6 EEB09409.1 - 0.53 9.5 10.1 0.69 9.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) NfeD PF01957.13 EEB09409.1 - 3.1 7.9 12.7 5.2 7.2 8.8 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Cyclin_N PF00134.18 EEB09410.1 - 5.3e-09 35.7 0.1 1.6e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain PIP5K PF01504.13 EEB09410.1 - 0.012 14.7 0.5 0.02 13.9 0.3 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TFIIB PF00382.14 EEB09410.1 - 0.036 13.8 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EEB09410.1 - 0.055 13.3 0.4 0.055 13.3 0.3 2.4 3 0 0 3 3 3 0 Cyclin, C-terminal domain WD40 PF00400.27 EEB09411.1 - 3.4e-08 33.0 0.3 0.00023 20.9 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Na_H_Exchanger PF00999.16 EEB09412.1 - 1.4e-66 224.6 35.6 7.1e-65 218.9 24.0 2.4 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family SMP_2 PF10144.4 EEB09412.1 - 0.027 13.6 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin Sedlin_N PF04628.8 EEB09414.2 - 7.4e-19 67.9 1.0 8.5e-19 67.7 0.7 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-UBR PF02207.15 EEB09415.2 - 2.4e-20 71.9 8.3 6.7e-20 70.5 5.7 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EEB09415.2 - 9.5e-07 28.4 0.1 2.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SUR7 PF06687.7 EEB09416.1 - 1.4e-13 50.9 18.7 8.6e-12 45.0 13.0 2.0 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.18 EEB09416.1 - 0.0045 16.8 13.5 0.0045 16.8 9.4 2.0 1 1 0 2 2 2 1 Membrane-associating domain Amastin PF07344.6 EEB09416.1 - 0.23 11.0 9.1 0.022 14.3 3.1 1.7 2 1 0 2 2 2 0 Amastin surface glycoprotein Pex24p PF06398.6 EEB09416.1 - 7.2 5.3 5.8 8.6 5.0 4.0 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin CH PF00307.26 EEB09417.2 - 4.3e-42 142.5 0.2 3.3e-22 78.5 0.0 3.3 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EEB09417.2 - 2.1e-09 36.8 0.0 1.5e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 EEB09417.2 - 1.8e-08 34.2 0.0 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.27 EEB09417.2 - 9e-05 21.5 0.3 0.00046 19.2 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EEB09417.2 - 0.0006 19.4 0.0 0.0006 19.4 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain EF-hand_5 PF13202.1 EEB09417.2 - 0.0047 16.1 0.0 0.0047 16.1 0.0 2.9 3 0 0 3 3 2 1 EF hand EF-hand_8 PF13833.1 EEB09417.2 - 0.011 15.3 0.0 0.051 13.2 0.0 2.2 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 EEB09417.2 - 0.019 15.0 1.3 0.057 13.5 0.2 2.4 2 0 0 2 2 1 0 EF-hand domain pair Hat1_N PF10394.4 EEB09417.2 - 0.065 13.2 4.1 0.24 11.4 1.2 2.3 2 0 0 2 2 2 0 Histone acetyl transferase HAT1 N-terminus FNIP_M PF14637.1 EEB09417.2 - 0.18 11.3 4.1 0.35 10.4 0.4 2.6 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Occludin_ELL PF07303.8 EEB09417.2 - 3.3 8.4 10.8 1.1 10.0 1.0 3.6 2 1 1 3 3 3 0 Occludin homology domain Pkinase_Tyr PF07714.12 EEB09418.2 - 6.6e-08 31.9 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEB09418.2 - 9.6e-08 31.4 0.0 2.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EEB09418.2 - 0.00063 19.6 0.1 0.67 10.1 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EEB09418.2 - 0.0043 17.3 0.0 1.5 9.1 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats CLASP_N PF12348.3 EEB09418.2 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 CLASP N terminal RIX1 PF08167.7 EEB09418.2 - 0.092 12.4 1.9 0.96 9.1 0.1 3.1 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Shugoshin_N PF07558.6 EEB09419.2 - 2e-11 43.4 12.2 5e-11 42.1 8.4 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EEB09419.2 - 1.7e-08 33.7 2.2 1.7e-08 33.7 1.5 3.2 4 0 0 4 4 4 1 Shugoshin C terminus SnAC PF14619.1 EEB09419.2 - 0.03 14.4 1.0 0.03 14.4 0.7 2.9 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex HALZ PF02183.13 EEB09419.2 - 10 5.9 10.0 0.69 9.6 3.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper AIP3 PF03915.8 EEB09420.1 - 1e-81 275.0 20.8 2.3e-81 273.9 14.4 1.6 1 0 0 1 1 1 1 Actin interacting protein 3 Baculo_PEP_C PF04513.7 EEB09420.1 - 3.1 7.6 15.5 1.4 8.6 1.9 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1761 PF08570.5 EEB09421.1 - 9.3e-21 74.1 1.5 1.1e-20 73.9 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L44 PF00935.14 EEB09422.1 - 1.2e-32 111.7 11.3 1.6e-32 111.3 7.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EEB09422.1 - 0.4 10.9 6.4 0.41 10.9 0.8 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 Thymidylat_synt PF00303.14 EEB09423.1 - 5.2e-113 376.5 0.0 8.2e-113 375.8 0.0 1.3 1 0 0 1 1 1 1 Thymidylate synthase Flavoprotein PF02441.14 EEB09423.1 - 7.1e-44 148.5 0.8 1.4e-43 147.6 0.6 1.5 1 0 0 1 1 1 1 Flavoprotein TFIIF_alpha PF05793.7 EEB09423.1 - 0.35 9.1 2.7 0.51 8.6 1.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CTP_transf_2 PF01467.21 EEB09424.1 - 5.1e-19 68.8 0.0 6.5e-14 52.2 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase Metallophos_2 PF12850.2 EEB09425.2 - 2.4e-15 56.7 0.0 2.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEB09425.2 - 0.0083 15.5 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.19 EEB09427.1 - 9.9e-14 51.1 0.1 1.5e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB09427.1 - 0.00046 20.2 0.1 0.00091 19.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEB09427.1 - 0.0025 17.9 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB09427.1 - 0.0058 16.3 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Glutaredoxin PF00462.19 EEB09428.1 - 4.4e-17 61.8 0.1 6.7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EEB09428.1 - 0.00037 20.6 0.2 0.00072 19.7 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 EEB09428.1 - 0.0037 16.8 0.2 0.007 15.9 0.1 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain DUF836 PF05768.9 EEB09428.1 - 0.0077 16.4 0.0 0.0098 16.1 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.1 EEB09428.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PI31_Prot_C PF08577.6 EEB09429.1 - 1.4e-08 35.2 10.6 1.4e-08 35.2 7.3 2.9 3 1 0 3 3 3 1 PI31 proteasome regulator GMP_synt_C PF00958.17 EEB09430.2 - 1e-37 127.6 0.0 2.3e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EEB09430.2 - 1.8e-37 128.6 0.0 3.1e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EEB09430.2 - 1.9e-07 30.2 0.0 7.5e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EEB09430.2 - 1.7e-06 27.6 0.0 4e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.14 EEB09430.2 - 0.00019 20.5 0.1 0.00032 19.8 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.11 EEB09430.2 - 0.00067 18.3 0.0 0.0018 16.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 EEB09430.2 - 0.0017 17.7 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EEB09430.2 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 EEB09430.2 - 0.037 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family MetJ PF01340.15 EEB09430.2 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Asn_synthase PF00733.16 EEB09430.2 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase IF3_C PF00707.17 EEB09431.1 - 0.00081 19.0 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain DUF868 PF05910.7 EEB09431.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) IF3_N PF05198.11 EEB09431.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain AA_permease PF00324.16 EEB09433.1 - 9e-138 459.5 27.7 1e-137 459.3 19.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB09433.1 - 6.9e-39 133.5 35.5 9.1e-39 133.1 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease SAPS PF04499.10 EEB09434.1 - 1.1e-166 555.2 4.1 1.1e-166 555.2 2.8 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Arm PF00514.18 EEB09434.1 - 0.16 11.8 0.1 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Complex1_51K PF01512.12 EEB09435.1 - 1.5e-44 151.3 0.0 2.6e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EEB09435.1 - 4.6e-10 38.4 0.0 9.9e-10 37.4 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EEB09435.1 - 2.6e-08 33.6 0.0 5.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3507 PF12015.3 EEB09435.1 - 0.041 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) phage_tail_N PF08400.5 EEB09435.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal YjeF_N PF03853.10 EEB09436.1 - 6.8e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EEB09436.1 - 3.2e-07 30.8 16.8 3.7e-06 27.4 11.6 2.3 1 1 1 2 2 2 1 FDF domain LSM PF01423.17 EEB09436.1 - 0.00011 21.6 0.0 0.001 18.5 0.0 2.5 3 0 0 3 3 3 1 LSM domain SM-ATX PF14438.1 EEB09436.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.4 3 1 0 3 3 3 0 Ataxin 2 SM domain Peptidase_M16_C PF05193.16 EEB09437.1 - 2.6e-33 115.2 0.0 6.1e-33 114.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEB09437.1 - 3.8e-28 98.1 0.1 1.1e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.9 EEB09437.1 - 0.075 12.7 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Methyltransf_23 PF13489.1 EEB09438.1 - 2.5e-23 82.5 0.0 3.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB09438.1 - 7.9e-22 77.5 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB09438.1 - 3.7e-19 68.8 0.0 4.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB09438.1 - 2.8e-16 60.0 0.0 4.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB09438.1 - 9.8e-16 58.0 0.0 1.9e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEB09438.1 - 1.2e-11 44.2 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EEB09438.1 - 1.7e-10 41.1 0.0 2.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEB09438.1 - 2.7e-09 36.5 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EEB09438.1 - 9.5e-09 34.7 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEB09438.1 - 8.2e-08 32.2 0.0 2.1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEB09438.1 - 1.6e-06 27.6 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EEB09438.1 - 1.6e-05 23.7 0.0 2.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 EEB09438.1 - 1.8e-05 24.1 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 EEB09438.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EEB09438.1 - 5.3e-05 22.9 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEB09438.1 - 5.7e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EEB09438.1 - 0.0003 19.7 0.0 0.0004 19.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TPMT PF05724.6 EEB09438.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 EEB09438.1 - 0.00083 18.5 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EEB09438.1 - 0.0034 16.9 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_10 PF05971.7 EEB09438.1 - 0.052 12.6 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) 3HCDH_N PF02737.13 EEB09438.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_4 PF02390.12 EEB09438.1 - 0.06 12.3 0.0 0.77 8.7 0.0 2.0 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.5 EEB09438.1 - 0.075 12.5 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Snf7 PF03357.16 EEB09439.2 - 5.1e-44 149.6 19.9 5.8e-44 149.4 13.8 1.0 1 0 0 1 1 1 1 Snf7 EHN PF06441.7 EEB09439.2 - 0.23 11.3 3.7 3.8 7.4 2.6 2.3 1 1 0 1 1 1 0 Epoxide hydrolase N terminus Osmo_CC PF08946.5 EEB09439.2 - 0.23 11.4 0.0 0.23 11.4 0.0 3.6 3 1 1 4 4 4 0 Osmosensory transporter coiled coil NuA4 PF09340.5 EEB09439.2 - 0.25 10.9 3.8 0.68 9.6 2.5 2.0 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 NPV_P10 PF05531.7 EEB09439.2 - 0.35 11.1 19.2 0.12 12.5 3.2 3.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 EEB09439.2 - 0.38 10.3 0.0 0.38 10.3 0.0 4.1 2 1 2 4 4 4 0 Prefoldin subunit Allexi_40kDa PF05549.6 EEB09439.2 - 1.4 8.1 9.1 1.9 7.6 4.0 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ENTH PF01417.15 EEB09440.1 - 7.1e-49 164.8 0.1 1.2e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EEB09440.1 - 9.2e-31 105.7 176.2 1.5e+04 -22.5 78.8 9.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) ANTH PF07651.11 EEB09440.1 - 0.00037 19.3 0.1 0.0011 17.7 0.0 1.7 1 1 0 2 2 2 1 ANTH domain DUF3432 PF11914.3 EEB09440.1 - 0.0051 16.8 2.0 1.9 8.5 0.5 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) UIM PF02809.15 EEB09440.1 - 0.96 9.1 11.4 0.04 13.4 2.7 2.6 3 0 0 3 3 3 0 Ubiquitin interaction motif TPR_MLP1_2 PF07926.7 EEB09441.1 - 2.2e-22 79.2 22.8 2.2e-22 79.2 15.8 19.2 4 4 12 17 17 17 6 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EEB09441.1 - 1.2e-05 23.2 60.3 1.2e-05 23.2 41.8 7.5 2 1 3 5 5 5 1 Myosin tail Tropomyosin_1 PF12718.2 EEB09441.1 - 0.00016 21.5 48.3 0.00041 20.1 9.7 16.8 6 3 7 15 15 15 5 Tropomyosin like IncA PF04156.9 EEB09441.1 - 1.9 8.0 347.4 0.015 14.9 20.8 17.2 1 1 14 16 16 16 0 IncA protein Med31 PF05669.7 EEB09442.1 - 2.3e-37 126.8 5.9 2.7e-37 126.6 4.1 1.0 1 0 0 1 1 1 1 SOH1 TypeIII_RM_meth PF12564.3 EEB09442.1 - 0.056 13.4 2.5 0.076 13.0 0.8 1.9 2 1 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit NT-C2 PF10358.4 EEB09443.1 - 2.5e-24 85.3 1.1 3.4e-24 84.9 0.8 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2428 PF10350.4 EEB09444.1 - 3.5e-64 216.2 0.0 5.6e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EEB09444.1 - 0.00066 19.5 1.2 14 6.0 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat DEAD PF00270.24 EEB09445.1 - 1.5e-37 128.7 0.2 2.5e-37 127.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09445.1 - 8.1e-23 80.0 0.5 1.2e-11 44.3 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEB09445.1 - 0.0016 18.2 2.0 0.0052 16.6 0.1 2.6 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit EutH PF04346.7 EEB09445.1 - 0.003 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH UCH PF00443.24 EEB09446.1 - 5.3e-87 291.3 0.1 2.9e-86 288.9 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEB09446.1 - 1.4e-18 67.3 1.4 2.2e-09 37.1 0.1 2.9 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EEB09446.1 - 8.2e-15 55.0 1.2 2.7e-14 53.3 0.1 2.6 2 0 0 2 2 2 1 DUSP domain Zn-ribbon_8 PF09723.5 EEB09446.1 - 0.012 15.5 3.7 0.5 10.3 1.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Antimicrobial_7 PF08102.6 EEB09446.1 - 0.037 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide PDH PF02153.12 EEB09447.2 - 1.1e-12 47.4 0.0 1.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EEB09447.2 - 2.5e-07 31.0 0.0 6.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EEB09447.2 - 4.2e-07 29.9 0.0 6.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEB09447.2 - 0.00039 19.6 0.0 0.00071 18.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EEB09447.2 - 0.00092 18.9 0.0 0.0025 17.5 0.0 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EEB09447.2 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EEB09447.2 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.4 EEB09447.2 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 EEB09447.2 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain V-ATPase_H_N PF03224.9 EEB09448.1 - 6.6e-07 28.7 2.8 9.9e-06 24.8 1.9 2.3 1 1 0 1 1 1 1 V-ATPase subunit H RICTOR_M PF14666.1 EEB09448.1 - 0.0005 19.1 0.7 0.048 12.6 0.1 2.6 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain RYDR_ITPR PF01365.16 EEB09448.1 - 0.0011 18.2 0.0 0.0031 16.7 0.0 1.7 1 0 0 1 1 1 1 RIH domain TFIID-18kDa PF02269.11 EEB09449.1 - 3.1e-26 90.9 0.1 3.6e-26 90.7 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EEB09449.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Aerolysin PF01117.15 EEB09449.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Aerolysin toxin Pkinase PF00069.20 EEB09450.1 - 1.9e-53 181.2 0.0 2.6e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09450.1 - 5.1e-30 104.3 0.0 7.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09450.1 - 0.0001 21.3 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB09450.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SAC3_GANP PF03399.11 EEB09451.1 - 1.6e-42 145.4 3.1 2.4e-42 144.8 2.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Thymidylate_kin PF02223.12 EEB09452.1 - 2.2e-49 167.3 0.0 2.5e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 EEB09452.1 - 0.00029 20.7 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEB09452.1 - 0.0094 15.9 0.0 0.017 15.0 0.0 1.4 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.15 EEB09452.1 - 0.014 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 EEB09452.1 - 0.025 13.8 0.0 0.051 12.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 EEB09452.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEB09452.1 - 0.07 13.0 0.1 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Methyltransf_11 PF08241.7 EEB09453.1 - 6.5e-19 68.2 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB09453.1 - 4.5e-17 62.0 0.0 5.8e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEB09453.1 - 9.3e-15 54.7 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEB09453.1 - 1.4e-14 54.6 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB09453.1 - 2.1e-12 47.3 0.0 4.7e-12 46.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEB09453.1 - 4.8e-11 42.7 0.0 7.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEB09453.1 - 3.7e-09 36.0 0.0 5.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EEB09453.1 - 5e-09 35.7 0.0 7.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EEB09453.1 - 2.3e-08 33.6 0.0 3.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 EEB09453.1 - 2.4e-08 34.2 0.0 5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEB09453.1 - 6.8e-08 31.9 0.1 1.4e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EEB09453.1 - 1.2e-07 31.1 0.1 2.2e-07 30.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EEB09453.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEB09453.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EEB09453.1 - 4.2e-05 23.1 0.0 0.00022 20.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 EEB09453.1 - 5.9e-05 22.5 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EEB09453.1 - 7.3e-05 22.0 0.0 9.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EEB09453.1 - 0.00016 20.1 0.0 0.00021 19.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 EEB09453.1 - 0.00018 20.4 0.0 0.00033 19.6 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.6 EEB09453.1 - 0.00019 20.2 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.11 EEB09453.1 - 0.00042 19.3 0.0 0.31 9.8 0.0 2.1 2 0 0 2 2 2 2 mRNA capping enzyme TehB PF03848.9 EEB09453.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DOT1 PF08123.8 EEB09453.1 - 0.0025 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 UPF0020 PF01170.13 EEB09453.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EEB09453.1 - 0.092 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF3049 PF11250.3 EEB09453.1 - 0.17 11.6 0.2 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) DUF2406 PF10295.4 EEB09454.1 - 3.5e-15 56.2 0.5 1.2e-14 54.5 0.0 2.1 2 1 0 2 2 2 1 Uncharacterised protein (DUF2406) Aldo_ket_red PF00248.16 EEB09455.1 - 3.1e-47 160.7 0.0 3.7e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1737 PF08410.5 EEB09455.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Apc5 PF12862.2 EEB09456.1 - 5.5e-35 119.0 5.0 2.9e-34 116.7 3.4 2.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 UBX PF00789.15 EEB09457.1 - 5.2e-13 48.8 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Ribosomal_S4e PF00900.15 EEB09458.1 - 6.8e-33 112.1 0.6 1.4e-32 111.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EEB09458.1 - 3e-19 68.5 5.5 6.2e-19 67.5 3.8 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EEB09458.1 - 3.8e-07 29.4 0.0 8.8e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEB09458.1 - 3.3e-05 23.4 1.3 3.3e-05 23.4 0.9 2.6 3 0 0 3 3 3 1 KOW motif Abhydrolase_5 PF12695.2 EEB09459.1 - 2.4e-13 50.0 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEB09459.1 - 9.5e-10 38.7 0.0 7.1e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEB09459.1 - 0.0055 16.1 0.0 0.0084 15.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEB09459.1 - 0.12 11.9 0.0 0.59 9.6 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ribonuc_red_lgC PF02867.10 EEB09460.2 - 1.8e-217 723.2 0.0 3.3e-217 722.3 0.0 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EEB09460.2 - 5.8e-24 83.7 0.0 1.7e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EEB09460.2 - 2.3e-15 56.7 0.1 7.8e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Ras PF00071.17 EEB09461.1 - 1.1e-56 190.6 0.0 1.3e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB09461.1 - 9.3e-16 58.4 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB09461.1 - 2.1e-07 30.3 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB09461.1 - 0.00012 21.6 0.1 0.00052 19.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEB09461.1 - 0.00056 19.1 0.0 0.00075 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEB09461.1 - 0.016 14.3 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EEB09461.1 - 0.018 14.5 0.0 11 5.4 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TRP PF06011.7 EEB09462.1 - 5.5e-94 315.2 32.3 7.5e-94 314.7 22.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEB09462.1 - 3.7e-38 130.7 0.9 6e-38 130.0 0.7 1.3 1 0 0 1 1 1 1 ML-like domain Cortexin PF11057.3 EEB09462.1 - 3.5 7.2 7.9 7.1 6.3 0.2 3.4 3 0 0 3 3 3 0 Cortexin of kidney DEAD PF00270.24 EEB09463.1 - 1.2e-45 155.0 0.0 3.1e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEB09463.1 - 1.3e-22 79.0 0.5 2.5e-22 78.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEB09463.1 - 3e-20 71.8 0.0 6.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EEB09463.1 - 0.029 13.6 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain ResIII PF04851.10 EEB09463.1 - 0.28 10.9 2.0 0.58 9.9 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SH2_2 PF14633.1 EEB09464.1 - 5.7e-94 313.2 0.1 1.4e-93 312.0 0.1 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EEB09464.1 - 3.6e-45 152.7 5.7 3.6e-45 152.7 3.9 3.0 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EEB09464.1 - 5.1e-44 148.6 0.0 1.1e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EEB09464.1 - 9.9e-44 148.5 0.0 2.7e-43 147.1 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EEB09464.1 - 7.5e-28 96.9 1.3 7.5e-28 96.9 0.9 2.6 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EEB09464.1 - 3.3e-22 78.4 20.3 3.3e-22 78.4 14.1 4.0 3 1 1 4 4 4 1 Acidic N-terminal SPT6 S1 PF00575.18 EEB09464.1 - 8.6e-07 28.9 0.0 2.6e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EEB09464.1 - 3.3e-05 23.5 0.0 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.2 EEB09464.1 - 9.1e-05 22.3 0.0 0.00041 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif MRC1 PF09444.5 EEB09465.1 - 3.1e-24 85.9 9.8 3.1e-24 85.9 6.8 4.0 4 1 0 4 4 4 1 MRC1-like domain Ribosomal_S25 PF03297.10 EEB09466.1 - 3e-37 126.8 2.4 3.4e-37 126.6 1.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein PaaX PF07848.7 EEB09466.1 - 0.073 13.0 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein AA_permease_2 PF13520.1 EEB09467.1 - 2.9e-45 154.5 49.1 3.6e-45 154.2 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEB09467.1 - 1.1e-25 89.8 41.4 1.6e-25 89.4 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease DJ-1_PfpI PF01965.19 EEB09468.2 - 7.6e-24 83.8 0.1 1.6e-23 82.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEB09468.2 - 0.00014 21.3 0.2 0.00043 19.7 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EEB09468.2 - 0.0086 15.3 0.0 0.015 14.5 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase FTR1 PF03239.9 EEB09469.1 - 3.9e-96 321.6 11.6 4.9e-96 321.2 8.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ferric_reduct PF01794.14 EEB09469.1 - 0.00018 21.6 2.7 0.00028 20.9 0.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NfeD PF01957.13 EEB09469.1 - 0.0026 17.8 9.7 0.12 12.5 0.0 3.7 4 0 0 4 4 4 2 NfeD-like C-terminal, partner-binding DUF3311 PF11755.3 EEB09469.1 - 0.0032 16.9 1.7 0.016 14.7 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3311) DUF3112 PF11309.3 EEB09469.1 - 0.0063 16.3 1.3 0.0063 16.3 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3112) YajC PF02699.10 EEB09469.1 - 0.0091 15.6 0.1 3.4 7.3 0.1 3.0 2 0 0 2 2 2 1 Preprotein translocase subunit DUF2615 PF11027.3 EEB09469.1 - 0.034 14.0 0.1 0.59 10.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF3671 PF12420.3 EEB09469.1 - 0.067 13.1 6.9 4.6 7.2 0.1 3.7 3 2 0 3 3 3 0 Protein of unknown function PsaL PF02605.10 EEB09469.1 - 0.13 11.7 5.8 1.1 8.8 0.1 2.6 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI DUF4381 PF14316.1 EEB09469.1 - 0.26 11.3 2.3 11 6.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4231 PF14015.1 EEB09469.1 - 0.37 10.7 6.5 0.72 9.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ETRAMP PF09716.5 EEB09469.1 - 3.5 7.6 4.9 59 3.7 0.3 3.9 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Cu-oxidase PF00394.17 EEB09470.1 - 3.5e-40 137.4 7.1 1.5e-39 135.4 0.2 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEB09470.1 - 1.9e-37 127.8 9.8 3.2e-35 120.6 1.0 3.6 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEB09470.1 - 1.6e-36 124.5 4.7 1.6e-35 121.3 1.0 3.3 3 1 1 4 4 4 1 Multicopper oxidase Glyco_hydro_98C PF08307.6 EEB09470.1 - 6.9e-05 22.2 0.0 0.00016 21.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain Aminotran_1_2 PF00155.16 EEB09471.1 - 7.5e-23 81.0 0.0 8.6e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II cobW PF02492.14 EEB09472.1 - 2.2e-35 121.7 0.0 2.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EEB09472.1 - 0.00011 21.0 0.7 0.0016 17.2 0.5 2.0 1 1 0 1 1 1 1 ArgK protein Pox_A32 PF04665.7 EEB09472.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_17 PF13207.1 EEB09472.1 - 0.0094 16.7 0.1 0.022 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEB09472.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EEB09472.1 - 0.027 13.4 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ResIII PF04851.10 EEB09472.1 - 0.036 13.9 0.1 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EEB09472.1 - 0.05 13.5 0.1 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EEB09472.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEB09472.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEB09472.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EEB09472.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Methyltransf_4 PF02390.12 EEB09473.1 - 3.5e-53 179.5 0.0 4.8e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEB09473.1 - 0.00021 21.8 0.0 0.00045 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EEB09473.1 - 0.00034 19.7 0.0 0.0007 18.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 EEB09473.1 - 0.00079 18.8 0.0 0.0018 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EEB09473.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEB09473.1 - 0.0056 17.1 0.0 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEB09473.1 - 0.0081 15.7 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEB09473.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EEB09473.1 - 0.025 15.0 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEB09473.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EEB09473.1 - 0.072 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EEB09473.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4599 PF15371.1 EEB09473.1 - 0.23 11.5 0.9 0.59 10.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) AICARFT_IMPCHas PF01808.13 EEB09474.1 - 4e-118 394.0 0.0 5.3e-118 393.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EEB09474.1 - 8.2e-25 86.5 0.0 1.6e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain COX7B PF05392.6 EEB09474.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB zf-CCCH PF00642.19 EEB09475.1 - 3.4e-20 71.2 21.5 2.8e-12 45.9 3.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEB09475.1 - 0.019 14.9 2.7 0.019 14.9 1.9 3.1 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type SHR3_chaperone PF08229.6 EEB09476.2 - 1.8e-29 102.0 0.9 4.1e-29 100.9 0.6 1.6 1 1 0 1 1 1 1 ER membrane protein SH3 TrbH PF07283.6 EEB09477.2 - 0.0031 17.3 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Conjugal transfer protein TrbH PSP1 PF04468.7 EEB09478.2 - 4.6e-33 113.0 0.4 9.1e-33 112.1 0.3 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NUC173 PF08161.7 EEB09479.1 - 7.1e-15 54.8 4.8 7e-07 28.7 0.0 4.4 4 1 1 5 5 5 2 NUC173 domain HEAT PF02985.17 EEB09479.1 - 0.011 15.7 0.0 23 5.4 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EEB09479.1 - 0.16 12.5 1.0 74 4.0 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 EEB09479.1 - 0.22 11.3 3.3 5.5 6.7 0.0 4.2 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Gag_spuma PF03276.9 EEB09479.1 - 1.2 7.4 12.1 1.9 6.7 8.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein CBF PF03914.12 EEB09479.1 - 4.4 6.7 9.9 0.22 10.9 0.1 3.6 4 0 0 4 4 4 0 CBF/Mak21 family HMGL-like PF00682.14 EEB09480.2 - 1.9e-73 247.0 0.2 3e-73 246.3 0.1 1.3 1 0 0 1 1 1 1 HMGL-like DUF2624 PF11116.3 EEB09480.2 - 0.057 13.9 0.1 6.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Ribosomal_L16 PF00252.13 EEB09481.1 - 5.3e-31 107.1 0.1 6.6e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SKN1 PF03935.10 EEB09482.1 - 4.5e-09 34.9 0.0 5.6e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3185 PF11381.3 EEB09482.1 - 0.12 12.1 0.2 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) VPEP PF07589.6 EEB09482.1 - 5 7.1 5.3 9.5 6.2 3.7 1.4 1 0 0 1 1 1 0 PEP-CTERM motif TMEM223 PF14640.1 EEB09483.1 - 0.00052 19.9 0.1 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 Transmembrane protein 223 STE3 PF02076.10 EEB09483.1 - 0.037 13.1 1.6 0.057 12.4 1.1 1.2 1 0 0 1 1 1 0 Pheromone A receptor AAA PF00004.24 EEB09484.1 - 4.1e-46 156.4 0.0 8.7e-43 145.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEB09484.1 - 9.1e-07 29.0 1.1 1.3e-05 25.3 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EEB09484.1 - 9.6e-07 28.3 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEB09484.1 - 3.9e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEB09484.1 - 0.00013 21.7 0.5 0.0011 18.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEB09484.1 - 0.00039 20.5 0.0 0.086 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EEB09484.1 - 0.00055 20.0 4.1 0.011 15.8 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EEB09484.1 - 0.001 18.5 0.1 0.0086 15.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEB09484.1 - 0.0011 18.6 0.0 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EEB09484.1 - 0.0022 18.8 0.1 0.033 15.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEB09484.1 - 0.0037 17.1 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Bromodomain PF00439.20 EEB09484.1 - 0.0038 17.0 0.1 0.021 14.7 0.0 2.3 2 0 0 2 2 1 1 Bromodomain ABC_tran PF00005.22 EEB09484.1 - 0.0039 17.4 0.2 0.063 13.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.7 EEB09484.1 - 0.004 16.8 0.2 0.031 13.9 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EEB09484.1 - 0.0059 16.5 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EEB09484.1 - 0.0078 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 EEB09484.1 - 0.01 16.1 0.0 0.07 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EEB09484.1 - 0.025 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EEB09484.1 - 0.027 13.6 0.0 0.064 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EEB09484.1 - 0.037 13.9 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEB09484.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEB09485.2 - 1.7e-09 38.5 0.1 3.9e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEB09485.2 - 3.9e-08 33.6 0.0 1.2e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEB09485.2 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EEB09485.2 - 0.015 15.1 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEB09485.2 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EEB09485.2 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EEB09485.2 - 0.061 12.8 0.6 0.5 9.8 0.4 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 EEB09485.2 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 EEB09486.1 - 1.9e-52 173.3 15.3 1.2e-09 37.6 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEB09486.1 - 0.0061 14.7 4.1 1.7 6.7 0.2 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEB09486.1 - 0.032 12.9 1.1 1.2 7.8 0.0 3.4 2 1 2 4 4 4 0 Nup133 N terminal like S10_plectin PF03501.10 EEB09487.1 - 3.3e-43 145.4 0.1 3.9e-43 145.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain CENP-N PF05238.8 EEB09488.1 - 1.2e-66 225.4 0.0 1.6e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Nuc_sug_transp PF04142.10 EEB09489.2 - 9.4e-61 204.9 4.4 1.7e-60 204.1 3.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EEB09489.2 - 2.6e-09 36.4 4.9 2.6e-09 36.4 3.4 1.3 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EEB09489.2 - 3.6e-09 36.8 0.8 3.6e-09 36.8 0.6 2.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EEB09489.2 - 5.2e-08 32.6 7.4 2e-06 27.5 0.3 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EEB09489.2 - 9.4e-07 28.9 2.2 9.4e-07 28.9 1.5 2.5 2 0 0 2 2 2 1 EamA-like transporter family DuoxA PF10204.4 EEB09489.2 - 0.0068 15.5 3.3 0.23 10.4 1.3 2.1 2 0 0 2 2 2 2 Dual oxidase maturation factor DUF202 PF02656.10 EEB09489.2 - 0.12 12.5 1.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Na_Ca_ex PF01699.19 EEB09490.1 - 6.3e-43 145.7 38.3 2.4e-23 82.3 7.9 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Mad3_BUB1_I PF08311.7 EEB09491.1 - 1.3e-40 138.0 0.6 2.4e-40 137.2 0.4 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 EEB09491.1 - 0.27 11.2 1.8 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.13 EEB09492.1 - 7.5e-51 171.9 0.0 1.2e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EEB09492.1 - 2e-30 105.4 0.0 4e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Syntaxin-18_N PF10496.4 EEB09493.1 - 8.3e-11 41.5 0.8 8.3e-11 41.5 0.5 2.3 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus FH2 PF02181.18 EEB09494.1 - 1.9e-58 198.1 11.1 1.9e-58 198.1 7.7 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EEB09494.1 - 6.7e-13 48.4 2.8 1.1e-12 47.7 0.0 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EEB09494.1 - 6.4e-06 25.7 1.2 6.4e-06 25.7 0.8 2.8 1 1 1 2 2 2 1 Diaphanous FH3 Domain MoeA_C PF03454.10 EEB09494.1 - 0.027 14.4 0.1 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Drf_FH1 PF06346.7 EEB09494.1 - 0.28 10.6 114.7 1.2 8.6 79.5 1.8 1 1 0 1 1 1 0 Formin Homology Region 1 WD40 PF00400.27 EEB09495.1 - 1.1e-51 170.9 35.0 3.7e-08 32.9 0.1 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat Med6 PF04934.9 EEB09496.1 - 1.7e-49 166.9 0.1 2.4e-49 166.5 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MFS_1 PF07690.11 EEB09497.2 - 6.4e-38 130.3 25.4 9.2e-38 129.8 17.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1281 PF06924.6 EEB09497.2 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Fungal_trans PF04082.13 EEB09498.2 - 1.3e-21 76.6 1.9 2.7e-21 75.6 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB09498.2 - 0.00024 20.9 14.0 0.00045 20.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPRTase PF14681.1 EEB09499.1 - 4.8e-55 185.9 0.3 4.5e-49 166.4 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEB09499.1 - 1.2e-08 34.7 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1688 PF07958.6 EEB09500.1 - 3.1e-146 487.1 0.0 3.5e-146 487.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GTP_CH_N PF12471.3 EEB09501.2 - 5.5e-90 300.2 0.0 8.8e-90 299.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EEB09501.2 - 1.5e-14 53.5 0.0 2.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Zn_clus PF00172.13 EEB09502.1 - 0.0038 17.1 7.7 0.0038 17.1 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPRTase PF14681.1 EEB09503.1 - 2.5e-69 232.6 0.0 2.8e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEB09503.1 - 0.00027 20.6 0.0 0.00065 19.4 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NSs PF11073.3 EEB09503.1 - 0.05 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Transp_cyt_pur PF02133.10 EEB09504.1 - 4.6e-167 556.0 40.9 5.3e-167 555.8 28.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 EEB09505.1 - 2.6e-45 154.6 54.2 2.6e-45 154.6 37.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB09505.1 - 6.1e-16 57.7 26.0 6.5e-16 57.6 17.3 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEB09505.1 - 5e-09 35.2 15.0 5e-09 35.2 10.4 3.7 2 2 0 3 3 3 1 Sugar (and other) transporter DUF2678 PF10856.3 EEB09505.1 - 0.092 12.4 4.9 0.089 12.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) N_NLPC_P60 PF12912.2 EEB09505.1 - 0.25 11.4 0.9 0.48 10.5 0.7 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Neurensin PF14927.1 EEB09505.1 - 0.74 9.2 3.5 0.35 10.2 0.2 2.2 2 1 0 2 2 2 0 Neurensin MFS_1 PF07690.11 EEB09506.2 - 4.4e-39 134.2 42.5 5.5e-37 127.3 29.0 3.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEB09506.2 - 1.8e-16 59.4 23.7 2.5e-16 59.0 16.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEB09506.2 - 3.6e-14 52.2 0.4 3.6e-14 52.2 0.3 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter EamA PF00892.15 EEB09506.2 - 0.0082 16.1 1.1 0.0082 16.1 0.8 4.5 3 2 1 4 4 4 1 EamA-like transporter family DUF373 PF04123.8 EEB09506.2 - 0.65 8.9 7.0 0.17 10.8 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Xan_ur_permease PF00860.15 EEB09507.1 - 2.3e-71 240.3 31.9 3.5e-69 233.1 22.1 2.1 1 1 0 1 1 1 1 Permease family AA_permease PF00324.16 EEB09508.1 - 4.8e-116 387.9 44.4 5.8e-116 387.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB09508.1 - 1.2e-28 99.8 47.0 1.4e-28 99.6 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM173 PF15009.1 EEB09508.1 - 4.1 6.1 4.8 6.4 5.4 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 173 OCD_Mu_crystall PF02423.10 EEB09509.1 - 3.6e-53 180.3 0.0 4.1e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEB09509.1 - 9.1e-06 25.8 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EEB09509.1 - 0.0044 16.0 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase FlgD_ig PF13860.1 EEB09510.2 - 9e-07 28.5 31.3 5.4 6.8 0.1 10.9 9 3 1 10 10 10 7 FlgD Ig-like domain Scm3 PF10384.4 EEB09511.1 - 1.5e-20 72.4 0.0 2.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Centromere protein Scm3 NTF2 PF02136.15 EEB09511.1 - 2e-13 50.7 0.1 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EEB09511.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 ComZ PF10815.3 EEB09512.1 - 0.039 13.7 0.5 0.11 12.2 0.1 1.9 2 1 1 3 3 3 0 ComZ Nitrate_red_del PF02613.10 EEB09512.1 - 0.11 12.2 0.2 16 5.3 0.0 2.2 1 1 1 2 2 2 0 Nitrate reductase delta subunit CBM_15 PF03426.9 EEB09512.1 - 0.15 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DIPSY PF11763.3 EEB09513.2 - 5.4e-20 71.4 1.6 5.4e-20 71.4 1.1 3.4 3 0 0 3 3 3 1 Cell-wall adhesin ligand-binding C-terminal FlgD_ig PF13860.1 EEB09513.2 - 5 6.9 31.6 6.9 6.4 0.1 9.0 9 2 1 10 10 10 0 FlgD Ig-like domain ArfGap PF01412.13 EEB09514.1 - 5.7e-41 138.9 0.1 1.2e-40 137.8 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MFS_1 PF07690.11 EEB09515.1 - 1.8e-37 128.8 44.2 1.8e-37 128.8 30.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB09515.1 - 2.4e-10 39.6 12.0 2.4e-10 39.6 8.3 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter DUF1370 PF07114.6 EEB09515.1 - 0.031 13.4 1.7 0.086 12.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) Glyoxalase PF00903.20 EEB09516.1 - 1.5e-39 134.9 0.3 2.8e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEB09516.1 - 4.7e-29 101.1 0.1 2.2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEB09516.1 - 2.2e-21 75.8 0.0 1.1e-09 38.3 0.0 3.5 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEB09516.1 - 1.4e-07 31.5 0.0 0.00081 19.3 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase-like domain SIS PF01380.17 EEB09517.1 - 4.3e-55 184.8 0.2 4.9e-31 107.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EEB09517.1 - 2.9e-28 98.6 0.0 1.2e-18 66.9 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEB09517.1 - 8.6e-17 61.3 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEB09517.1 - 2e-11 43.6 0.0 6.4e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EEB09517.1 - 3.7e-07 29.1 0.0 6.9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EEB09517.1 - 0.021 14.5 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 SIS domain Glu_cys_ligase PF04262.9 EEB09518.1 - 0.024 13.1 0.1 0.027 12.9 0.1 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase V_ATPase_I PF01496.14 EEB09518.1 - 0.41 8.4 2.2 0.47 8.2 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2360 PF10152.4 EEB09518.1 - 1.8 8.8 5.9 0.36 11.0 0.8 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ammonium_transp PF00909.16 EEB09519.1 - 1.5e-115 385.8 30.4 1.8e-115 385.6 21.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family WD40 PF00400.27 EEB09520.1 - 5e-31 105.4 14.6 8e-08 31.8 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEB09520.1 - 1.4e-05 23.5 8.7 0.053 11.6 0.2 3.9 2 1 0 3 3 3 3 Nucleoporin Nup120/160 RabGAP-TBC PF00566.13 EEB09521.2 - 5.5e-49 166.5 0.0 5.5e-49 166.5 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EEB09522.1 - 9.7e-69 231.3 0.0 2.6e-68 230.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09522.1 - 2.1e-29 102.4 0.1 5e-28 97.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09522.1 - 3.3e-09 36.1 0.1 2.8e-06 26.5 0.0 3.0 1 1 1 2 2 2 2 Kinase-like MARCKS PF02063.12 EEB09522.1 - 0.0044 16.9 19.5 0.0074 16.1 13.5 1.3 1 0 0 1 1 1 1 MARCKS family Kdo PF06293.9 EEB09522.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEB09522.1 - 0.038 13.7 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family SOBP PF15279.1 EEB09522.1 - 3.5 7.9 8.7 3.1 8.0 5.1 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein RAP1 PF07218.6 EEB09522.1 - 9.1 4.2 12.7 13 3.7 8.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Met_10 PF02475.11 EEB09523.1 - 2.7e-09 36.9 0.0 5.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEB09523.1 - 0.0024 17.9 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EEB09524.2 - 2.8e-23 82.1 0.0 9.4e-20 70.5 0.1 3.1 1 1 1 2 2 2 2 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 EEB09524.2 - 2e-10 40.3 0.0 3.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 EEB09524.2 - 1.7e-09 37.4 0.1 4.2e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEB09524.2 - 2.6e-06 26.9 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 EEB09524.2 - 2.9e-06 26.9 0.0 6.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EEB09524.2 - 5.7e-05 23.6 0.0 0.00016 22.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEB09524.2 - 6.2e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEB09524.2 - 7.6e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEB09524.2 - 0.00011 21.4 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEB09524.2 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEB09524.2 - 0.00036 20.8 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEB09524.2 - 0.003 18.0 0.0 0.0092 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EEB09524.2 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DUF1637 PF07847.7 EEB09524.2 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) Ubie_methyltran PF01209.13 EEB09524.2 - 0.06 12.4 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EEB09524.2 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Mito_carr PF00153.22 EEB09525.1 - 3.8e-40 135.4 8.2 2.7e-18 65.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 EEB09525.1 - 0.046 13.5 0.9 0.77 9.6 0.1 2.5 2 0 0 2 2 2 0 Colicin V production protein tRNA-synt_1 PF00133.17 EEB09526.1 - 1.4e-52 178.6 4.8 2.3e-32 111.8 3.5 5.8 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EEB09526.1 - 4.7e-35 120.5 0.0 1.2e-34 119.2 0.0 1.7 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EEB09526.1 - 1.4e-26 93.0 0.1 3.2e-20 72.1 0.0 4.4 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEB09526.1 - 5.9e-13 48.8 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EEB09526.1 - 0.00017 20.5 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) zf-ribbon_3 PF13248.1 EEB09526.1 - 0.00086 18.4 4.6 0.085 12.0 0.0 2.9 3 0 0 3 3 3 2 zinc-ribbon domain tRNA-synt_1e PF01406.14 EEB09526.1 - 0.00087 18.4 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.11 EEB09526.1 - 0.067 12.9 4.9 0.3 10.8 0.0 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain TF_Zn_Ribbon PF08271.7 EEB09526.1 - 0.19 11.0 2.3 5.4 6.4 0.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-NADH-PPase PF09297.6 EEB09526.1 - 0.35 10.4 2.2 6.4 6.3 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.4 EEB09526.1 - 2.2 8.0 6.5 7.9 6.2 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EEB09526.1 - 3.4 7.2 10.0 5.6 6.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain V-SNARE_C PF12352.3 EEB09527.1 - 9e-13 48.0 0.5 9e-13 48.0 0.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_S46 PF10459.4 EEB09527.1 - 0.076 11.4 2.0 0.091 11.1 1.4 1.0 1 0 0 1 1 1 0 Peptidase S46 Sec20 PF03908.8 EEB09527.1 - 0.088 12.5 2.9 0.15 11.8 0.0 2.3 1 1 2 3 3 3 0 Sec20 DUF349 PF03993.7 EEB09527.1 - 0.11 12.6 0.3 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Herpes_US9 PF06072.6 EEB09527.1 - 0.14 12.0 0.5 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Cornichon PF03311.9 EEB09528.1 - 3.7e-39 133.7 11.8 4.2e-39 133.6 8.2 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2269 PF10027.4 EEB09528.1 - 1.4 8.6 5.4 1.4 8.6 2.1 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF2340 PF10209.4 EEB09529.1 - 5.2e-47 159.0 1.6 5.8e-47 158.8 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) FAIM1 PF06905.8 EEB09529.1 - 0.029 13.5 0.1 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) RyR PF02026.11 EEB09529.1 - 0.065 13.2 0.8 0.11 12.5 0.2 1.6 2 0 0 2 2 2 0 RyR domain DUF739 PF05339.6 EEB09529.1 - 0.08 12.7 0.1 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF739) Ank_2 PF12796.2 EEB09530.2 - 0.03 14.6 0.6 0.049 13.9 0.4 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Clusterin PF01093.12 EEB09530.2 - 0.14 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Clusterin FAD_binding_8 PF08022.7 EEB09531.1 - 1.5e-22 79.4 0.0 2.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEB09531.1 - 3.1e-16 59.6 14.6 3.1e-16 59.6 10.2 2.7 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEB09531.1 - 6.2e-15 55.4 0.0 1.3e-13 51.1 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain SDF PF00375.13 EEB09531.1 - 0.0072 15.1 4.8 0.017 13.8 3.3 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF998 PF06197.8 EEB09531.1 - 0.046 13.0 6.2 0.023 13.9 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF998) NAD_binding_1 PF00175.16 EEB09531.1 - 0.093 13.3 0.0 0.73 10.4 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 EEB09531.1 - 5.2 6.3 24.8 0.84 8.9 9.7 2.8 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EEB09531.1 - 9.2 5.6 19.4 0.29 10.5 7.8 2.1 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 eIF2A PF08662.6 EEB09532.1 - 1.4e-41 142.3 2.9 9.6e-40 136.3 0.5 3.2 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EEB09532.1 - 0.00086 18.9 0.1 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEB09532.1 - 0.012 15.4 0.2 13 5.8 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Kinesin PF00225.18 EEB09533.2 - 5.4e-111 370.5 0.1 5.4e-111 370.5 0.0 3.1 2 1 0 2 2 2 1 Kinesin motor domain WXG100 PF06013.7 EEB09533.2 - 5.2 7.1 33.1 2.2 8.3 0.0 7.0 4 2 3 7 7 7 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 EEB09533.2 - 6.1 6.8 19.1 0.79 9.6 1.1 5.2 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Ribosomal_S28e PF01200.13 EEB09534.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EEB09535.1 - 3.1e-52 176.4 0.1 4.5e-52 175.9 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EEB09535.1 - 3.6e-26 90.8 0.2 6.8e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EEB09535.1 - 0.0015 18.1 0.1 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Red1 PF07964.6 EEB09536.1 - 5.1e-11 41.4 0.4 5.1e-11 41.4 0.3 2.7 3 0 0 3 3 3 1 Rec10 / Red1 bZIP_2 PF07716.10 EEB09537.1 - 7.8e-12 44.8 13.7 1.9e-11 43.6 9.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EEB09537.1 - 0.00011 22.1 12.9 0.00021 21.1 9.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EEB09537.1 - 0.0009 19.1 0.5 0.0027 17.6 0.3 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family XhlA PF10779.4 EEB09537.1 - 0.026 14.4 0.7 0.071 13.0 0.5 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Seryl_tRNA_N PF02403.17 EEB09537.1 - 0.096 12.7 4.6 0.15 12.0 2.3 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PEARLI-4 PF05278.7 EEB09537.1 - 0.15 11.4 3.7 0.38 10.1 2.6 1.6 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Neur_chan_memb PF02932.11 EEB09537.1 - 0.24 11.2 3.8 1.8 8.3 2.5 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-O PF09496.5 EEB09537.1 - 0.35 11.1 1.8 1.3 9.3 1.3 2.0 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component bZIP_Maf PF03131.12 EEB09537.1 - 2.4 8.5 10.3 0.34 11.2 3.1 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Acetyltransf_7 PF13508.1 EEB09538.1 - 2e-12 47.1 0.0 2.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEB09538.1 - 7.5e-10 38.7 0.0 1.3e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEB09538.1 - 0.00056 20.0 0.0 0.00071 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEB09538.1 - 0.0064 16.3 0.0 0.0087 15.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EEB09538.1 - 0.0067 16.9 0.1 0.71 10.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Ydc2-catalyt PF09159.5 EEB09539.1 - 1.7e-44 152.4 0.1 8.5e-44 150.0 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EEB09539.1 - 0.001 18.9 0.0 0.14 12.0 0.0 3.4 1 1 0 1 1 1 1 Poxvirus A22 protein SAP PF02037.22 EEB09539.1 - 0.0028 17.1 0.1 0.0054 16.2 0.1 1.5 1 0 0 1 1 1 1 SAP domain OrfB_IS605 PF01385.14 EEB09539.1 - 0.0029 17.0 0.3 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 Probable transposase Ribosomal_S9 PF00380.14 EEB09540.1 - 2.2e-34 118.2 0.0 3.1e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DLD PF14878.1 EEB09540.1 - 0.063 13.3 0.3 0.096 12.7 0.2 1.2 1 0 0 1 1 1 0 Death-like domain of SPT6 DKCLD PF08068.7 EEB09541.1 - 1.9e-31 107.7 0.1 4.6e-30 103.3 0.1 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EEB09541.1 - 1.3e-22 80.5 0.1 8.2e-20 71.4 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EEB09541.1 - 5.3e-22 77.3 2.0 1.1e-21 76.3 1.4 1.6 1 0 0 1 1 1 1 PUA domain CT47 PF15623.1 EEB09541.1 - 0.082 12.6 24.9 0.12 12.1 17.2 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 RNase_H2-Ydr279 PF09468.5 EEB09541.1 - 0.28 10.3 25.1 0.46 9.6 17.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_polI_A34 PF08208.6 EEB09541.1 - 3 7.4 39.5 5.9 6.5 27.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SNF2_N PF00176.18 EEB09542.2 - 1.1e-81 273.9 2.0 1.1e-81 273.9 1.4 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEB09542.2 - 1.7e-20 72.6 0.1 7.2e-20 70.7 0.1 2.1 1 0 0 1 1 1 1 Bromodomain HSA PF07529.8 EEB09542.2 - 1.7e-16 59.7 13.3 3.9e-16 58.5 7.1 3.2 3 0 0 3 3 3 1 HSA Helicase_C PF00271.26 EEB09542.2 - 1.4e-15 56.8 0.1 7.8e-15 54.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EEB09542.2 - 3.8e-13 49.3 0.6 3.8e-13 49.3 0.4 3.8 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.10 EEB09542.2 - 3.9e-07 30.0 2.6 1.2e-06 28.5 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Radical_SAM PF04055.16 EEB09543.1 - 6.8e-19 68.6 0.3 2e-18 67.1 0.1 1.9 2 1 1 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EEB09543.1 - 3.5e-13 49.4 0.0 9.6e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB09543.1 - 0.03 14.4 0.1 0.067 13.3 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEB09543.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EEB09543.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 EEB09544.1 - 1.8e-31 108.9 2.4 2.2e-31 108.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EEB09544.1 - 8.1e-19 68.5 0.0 1.6e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB09544.1 - 6.4e-16 59.4 0.0 2.7e-14 54.1 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEB09544.1 - 3.2e-08 33.4 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit P5-ATPase PF12409.3 EEB09544.1 - 2.6e-07 30.5 0.1 2.6e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter WD40 PF00400.27 EEB09545.1 - 3.3e-34 115.5 15.1 3.3e-08 33.0 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEB09545.1 - 1.5e-16 60.0 1.0 3.1e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex FUN14 PF04930.10 EEB09546.1 - 6e-14 52.1 0.2 8.5e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 FUN14 family DUF2982 PF11201.3 EEB09546.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2982) Pkinase PF00069.20 EEB09547.2 - 5.4e-62 209.2 0.0 1.3e-61 208.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09547.2 - 1.7e-27 96.1 0.0 2.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09547.2 - 0.0018 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEB09547.2 - 0.063 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.7 EEB09547.2 - 9.9 4.6 13.4 16 3.9 9.3 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.20 EEB09548.2 - 2.5e-55 187.4 0.0 3e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09548.2 - 1.1e-30 106.6 0.0 3.3e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09548.2 - 2.6e-05 23.3 0.0 4.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEB09548.2 - 0.0074 15.6 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EEB09548.2 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEB09548.2 - 0.076 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_2b PF00587.20 EEB09549.1 - 6.1e-36 123.5 0.1 1.1e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEB09549.1 - 4.2e-26 91.0 4.7 4.2e-26 91.0 3.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GED PF02212.13 EEB09549.1 - 0.003 17.4 1.7 0.0065 16.3 1.1 1.7 1 1 0 1 1 1 1 Dynamin GTPase effector domain D5_N PF08706.6 EEB09549.1 - 0.074 13.1 0.7 0.16 12.0 0.5 1.5 1 0 0 1 1 1 0 D5 N terminal like Peroxin-3 PF04882.7 EEB09550.1 - 6.2e-14 51.5 6.3 1.1e-08 34.3 4.4 3.1 1 1 0 1 1 1 1 Peroxin-3 Peptidase_M10 PF00413.19 EEB09550.1 - 0.071 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Matrixin UreF PF01730.11 EEB09551.1 - 4.7e-16 59.2 0.0 8.7e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 UreF DUF4647 PF15504.1 EEB09552.1 - 0.086 11.6 1.1 0.12 11.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RhoGAP PF00620.22 EEB09553.2 - 3.3e-39 133.9 0.0 7.1e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEB09553.2 - 1.4e-12 47.4 35.2 4.6e-08 33.0 4.5 3.8 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 EEB09553.2 - 3.3e-06 26.7 5.6 3.3e-06 26.7 3.9 3.7 2 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 EEB09554.1 - 0.0019 18.2 0.0 0.0085 16.1 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2HC_2 PF13913.1 EEB09554.1 - 0.73 9.5 0.0 0.73 9.5 0.0 3.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Nop25 PF09805.4 EEB09555.1 - 3.8e-30 104.7 22.0 4.4e-30 104.5 15.3 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Hid1 PF12722.2 EEB09555.1 - 0.22 9.1 8.2 0.21 9.2 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 EEB09555.1 - 3.8 6.3 8.0 4.8 6.0 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.6 EEB09555.1 - 4.6 7.0 16.7 6.2 6.6 11.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C3H1 PF10650.4 EEB09556.1 - 8e-10 38.0 0.4 1.2e-09 37.3 0.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Alveol-reg_P311 PF11092.3 EEB09557.1 - 0.093 12.7 0.3 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 Neuronal protein 3.1 (p311) Gly_transf_sug PF04488.10 EEB09558.1 - 2.4e-11 43.9 0.0 6.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CNH PF00780.17 EEB09559.1 - 1.7e-70 237.5 0.1 4.1e-70 236.3 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EEB09559.1 - 1.6e-36 125.2 0.0 4.1e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEB09559.1 - 9.9e-35 120.0 0.8 1.7e-34 119.2 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EEB09559.1 - 8.5e-14 51.0 0.0 1.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DEAD PF00270.24 EEB09560.1 - 3.8e-44 150.1 2.9 4.8e-44 149.8 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09560.1 - 3.6e-26 90.8 0.6 1.5e-25 88.8 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EEB09560.1 - 0.0017 17.9 0.2 0.0045 16.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEB09560.1 - 0.0019 18.0 0.1 0.0043 16.8 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Fanconi_A PF03511.9 EEB09560.1 - 0.0047 16.6 0.3 0.009 15.7 0.2 1.5 1 0 0 1 1 1 1 Fanconi anaemia group A protein DUF1253 PF06862.7 EEB09560.1 - 0.013 13.9 0.0 2.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EEB09560.1 - 0.029 14.0 0.9 0.08 12.6 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain CMS1 PF14617.1 EEB09560.1 - 0.038 13.0 0.0 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EEB09560.1 - 0.046 13.0 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SNF2_N PF00176.18 EEB09560.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 EEB09560.1 - 0.095 12.4 0.4 0.39 10.4 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EEB09560.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase Glyoxalase_5 PF14696.1 EEB09561.1 - 0.038 13.9 0.1 0.077 12.9 0.0 1.5 1 1 1 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Pinin_SDK_N PF04697.8 EEB09562.1 - 0.011 15.8 0.6 0.029 14.3 0.4 1.7 1 0 0 1 1 1 0 pinin/SDK conserved region Pkinase PF00069.20 EEB09563.2 - 6.2e-59 199.2 0.0 2.3e-58 197.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09563.2 - 5.3e-30 104.3 0.0 1.5e-29 102.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEB09563.2 - 1.4e-06 27.4 0.1 0.00015 20.8 0.1 2.8 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEB09563.2 - 0.0019 17.0 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EEB09563.2 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exotox-A_bind PF09101.5 EEB09563.2 - 0.039 13.0 0.1 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Exotoxin A binding DNA_binding_1 PF01035.15 EEB09564.2 - 2e-25 88.3 0.1 2.5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIIC_sub6 PF10419.4 EEB09565.1 - 5.4e-11 41.7 0.0 8.2e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit UQ_con PF00179.21 EEB09566.1 - 8.3e-42 141.9 0.0 9.4e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEB09566.1 - 2.3e-06 27.4 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEB09566.1 - 0.032 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EEB09566.1 - 0.063 13.1 0.2 0.083 12.7 0.1 1.4 1 1 0 1 1 1 0 RWD domain DUF1187 PF06688.6 EEB09567.2 - 0.023 14.8 0.1 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) EF-hand_1 PF00036.27 EEB09568.1 - 1.8e-15 54.9 0.5 0.0011 18.1 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EEB09568.1 - 7.7e-13 48.3 0.2 1.3e-08 34.8 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEB09568.1 - 8.3e-12 43.9 0.0 0.00012 21.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 EEB09568.1 - 1.4e-11 44.1 0.0 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEB09568.1 - 4.5e-08 32.5 3.2 0.011 15.3 0.0 3.7 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EEB09568.1 - 0.00018 20.6 1.8 0.92 8.9 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EEB09568.1 - 0.016 14.9 0.2 4.1 7.2 0.0 2.5 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EEB09568.1 - 0.029 13.9 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein N6_Mtase PF02384.11 EEB09568.1 - 0.047 12.7 0.1 0.051 12.6 0.1 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase DUF2040 PF09745.4 EEB09569.1 - 5.5e-24 84.4 17.6 5.5e-24 84.4 12.2 3.8 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Med22 PF06179.7 EEB09570.1 - 8.1e-20 70.8 1.7 1.2e-19 70.3 1.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Flagellar_rod PF05149.7 EEB09570.1 - 0.022 13.9 0.1 0.18 10.9 0.0 2.0 2 1 0 2 2 2 0 Paraflagellar rod protein Muted PF14942.1 EEB09570.1 - 0.1 12.4 2.0 0.28 11.0 0.1 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Prp19 PF08606.6 EEB09571.1 - 6.5e-28 96.2 1.5 1.6e-27 95.0 1.0 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EEB09571.1 - 1.8e-12 46.6 0.4 0.0017 18.1 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat U-box PF04564.10 EEB09571.1 - 0.00012 21.9 0.0 0.00085 19.2 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 EEB09571.1 - 0.027 13.9 0.0 0.093 12.2 0.0 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Baculo_PEP_N PF04512.7 EEB09571.1 - 0.058 13.3 0.0 0.59 10.1 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus WD40 PF00400.27 EEB09572.1 - 1.7e-18 65.6 5.1 6.2e-05 22.7 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EEB09572.1 - 0.032 14.5 2.6 3.4 8.0 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain Peptidase_S8 PF00082.17 EEB09573.1 - 6.6e-49 166.5 7.8 9.4e-49 166.0 5.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEB09573.1 - 6.7e-16 58.6 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pox_D3 PF04580.8 EEB09574.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein PQ-loop PF04193.9 EEB09575.1 - 6.1e-31 105.7 8.3 8.6e-21 73.2 0.8 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF3643 PF12356.3 EEB09575.1 - 0.032 13.5 2.1 0.04 13.2 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3643) DUF3671 PF12420.3 EEB09575.1 - 3.7 7.5 10.0 4 7.4 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function Sod_Fe_C PF02777.13 EEB09576.1 - 7.1e-17 61.1 0.5 8.8e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEB09576.1 - 2.1e-05 24.6 0.2 5.2e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain YmzC PF14157.1 EEB09576.1 - 0.13 12.0 1.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 YmzC-like protein Alpha-amylase PF00128.19 EEB09577.1 - 1.4e-65 221.8 0.0 1.8e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEB09577.1 - 1.4e-11 44.3 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Abhydro_lipase PF04083.11 EEB09578.2 - 9.4e-19 66.5 0.1 1.6e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEB09578.2 - 5.1e-18 65.4 0.0 7.3e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEB09578.2 - 5.9e-08 32.8 0.0 1.2e-07 31.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEB09578.2 - 1.4e-06 28.1 0.0 7.3e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEB09578.2 - 0.0031 16.9 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DLH PF01738.13 EEB09578.2 - 0.17 11.1 0.0 1.8 7.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family IMS PF00817.15 EEB09579.1 - 4.6e-40 136.8 0.0 1.9e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family Acetyltransf_13 PF13880.1 EEB09579.1 - 9.7e-25 86.1 0.0 2.6e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EEB09579.1 - 2.5e-12 46.1 0.9 2.5e-12 46.1 0.6 2.1 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EEB09579.1 - 0.00039 20.4 0.0 0.00089 19.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEB09579.1 - 0.00054 20.0 0.0 0.002 18.2 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MBOAT PF03062.14 EEB09580.1 - 5.6e-56 189.9 8.6 5.6e-56 189.9 5.9 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Eaf7 PF07904.8 EEB09581.1 - 7.1e-20 70.7 0.1 1.1e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 AA_permease PF00324.16 EEB09582.2 - 6.3e-88 295.2 43.0 1.4e-86 290.7 29.8 2.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEB09582.2 - 1.5e-33 116.0 44.1 2.3e-33 115.3 30.5 1.2 1 1 0 1 1 1 1 Amino acid permease YiaAB PF05360.9 EEB09582.2 - 0.0032 16.9 3.1 0.0032 16.9 2.2 3.7 5 0 0 5 5 5 1 yiaA/B two helix domain LisH PF08513.6 EEB09586.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 LisH C6 PF01681.12 EEB09587.1 - 0.6 10.2 2.9 1.1 9.3 2.0 1.6 1 1 0 1 1 1 0 C6 domain FBPase_3 PF01950.11 EEB09588.1 - 0.11 11.5 0.1 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase Stb3 PF10330.4 EEB09592.1 - 0.028 14.0 0.0 0.077 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative Sin3 binding protein ERG4_ERG24 PF01222.12 EEB09593.1 - 1e-145 485.5 18.3 1.3e-145 485.2 12.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEB09593.1 - 8.7e-06 25.1 0.7 8.7e-06 25.1 0.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EEB09593.1 - 0.0017 18.4 1.9 0.0039 17.2 0.0 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase Fungal_trans PF04082.13 EEB09594.1 - 2.5e-25 88.8 2.5 4.1e-25 88.1 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEB09594.1 - 4e-12 45.8 8.9 7e-12 45.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fork_head PF00250.13 EEB09595.1 - 3.3e-37 126.4 1.4 6.6e-37 125.4 1.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEB09595.1 - 7.9e-06 25.9 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ribosomal_S3_C PF00189.15 EEB09596.1 - 2.3e-15 56.5 0.0 4.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EEB09596.1 - 1.8e-14 53.0 0.1 3.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EEB09596.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ING PF12998.2 EEB09597.2 - 0.0046 17.2 0.4 0.02 15.1 0.3 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Topoisom_bac PF01131.15 EEB09598.1 - 1.2e-88 297.7 0.0 1.4e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EEB09598.1 - 1.7e-18 66.4 0.0 3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain BAG PF02179.11 EEB09599.1 - 4.7e-18 65.0 0.9 8.8e-18 64.1 0.6 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EEB09599.1 - 2.4e-07 30.0 0.1 5.4e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EEB09599.1 - 0.0002 20.9 0.1 0.00075 19.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EEB09599.1 - 0.029 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RNase_PH PF01138.16 EEB09600.1 - 1.9e-15 57.3 0.0 3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEB09600.1 - 0.0014 18.4 0.1 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Peptidase_S10 PF00450.17 EEB09601.1 - 3.3e-101 339.4 0.1 4e-101 339.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEB09601.1 - 0.0059 16.5 0.0 0.027 14.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEB09601.1 - 0.0068 15.6 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Med18 PF09637.5 EEB09602.2 - 4.4e-29 101.7 0.0 2.9e-28 99.0 0.0 1.8 1 1 0 1 1 1 1 Med18 protein Alg14 PF08660.6 EEB09603.1 - 1.1e-58 198.0 0.0 1.3e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PXA PF02194.10 EEB09604.1 - 3.4e-20 72.4 0.3 1.4e-19 70.3 0.1 2.0 2 0 0 2 2 2 1 PXA domain Catalase PF00199.14 EEB09605.1 - 9.5e-184 610.4 0.2 1.3e-183 610.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEB09605.1 - 1e-14 54.1 0.1 2.8e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive TMEM192 PF14802.1 EEB09605.1 - 0.22 10.3 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 TMEM192 family RNase_PH PF01138.16 EEB09606.1 - 7.2e-20 71.6 0.0 1.5e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEB09606.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 EEB09607.2 - 5.8e-39 131.5 3.5 5.3e-15 54.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEB09607.2 - 5.3e-29 99.3 11.1 5.5e-11 41.8 1.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEB09607.2 - 6e-10 38.5 2.9 0.022 14.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EEB09607.2 - 1.1e-06 28.1 0.4 0.27 10.9 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEB09607.2 - 0.00014 21.5 2.4 0.27 11.0 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Dsh_C PF12316.3 EEB09607.2 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal D-ser_dehydrat PF14031.1 EEB09608.1 - 4.2e-27 94.1 0.2 2.2e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EEB09608.1 - 2.2e-16 60.0 0.1 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MFS_1 PF07690.11 EEB09609.1 - 9.4e-25 87.0 26.1 9.4e-25 87.0 18.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EEB09610.1 - 6.9e-28 97.3 28.4 1.1e-27 96.7 19.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NicO PF03824.11 EEB09611.1 - 2.6e-53 181.1 15.7 3.7e-53 180.6 10.9 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF4646 PF15496.1 EEB09612.1 - 4.3e-27 94.6 0.0 7.7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EEB09612.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family C6 PF01681.12 EEB09614.1 - 0.079 13.0 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 C6 domain Sybindin PF04099.7 EEB09617.1 - 2.4e-21 75.9 0.8 3.6e-21 75.3 0.5 1.3 1 1 0 1 1 1 1 Sybindin-like family Fcf2 PF08698.6 EEB09618.1 - 4.4e-30 103.6 0.1 1.5e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing RFX_DNA_binding PF02257.10 EEB09619.2 - 6.1e-33 112.8 0.3 1.7e-32 111.4 0.2 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain tRNA-synt_1b PF00579.20 EEB09620.2 - 4.2e-68 229.6 0.0 7.6e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CLASP_N PF12348.3 EEB09621.1 - 1.6e-81 272.9 10.8 3.8e-70 235.7 0.5 2.8 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.1 EEB09621.1 - 0.00022 21.4 1.1 0.62 10.3 0.0 4.9 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.17 EEB09621.1 - 0.0025 17.7 0.1 80 3.7 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat TPP_enzyme_N PF02776.13 EEB09622.1 - 5.8e-32 110.5 0.0 9.1e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEB09622.1 - 6.3e-25 87.5 0.0 1.6e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEB09622.1 - 6.4e-18 64.7 0.0 2.5e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEB09622.1 - 0.00056 18.9 0.0 0.00091 18.2 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase VWA_2 PF13519.1 EEB09622.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Lyase_1 PF00206.15 EEB09623.2 - 4.3e-118 394.0 0.0 5.5e-118 393.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EEB09623.2 - 1e-21 76.7 0.0 2.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus UPF0154 PF03672.8 EEB09623.2 - 0.08 12.5 0.1 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Proteasom_PSMB PF10508.4 EEB09624.1 - 7e-11 41.0 0.2 1.4e-10 40.0 0.0 1.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit RasGEF_N_2 PF14663.1 EEB09624.1 - 0.0073 16.2 0.3 1.4 8.9 0.0 3.0 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Flavokinase PF01687.12 EEB09625.1 - 1.3e-40 138.1 0.0 1.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase RHH_3 PF12651.2 EEB09625.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain WD40 PF00400.27 EEB09626.2 - 6.8e-06 25.7 5.9 0.029 14.2 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat CPSF_A PF03178.10 EEB09626.2 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 1 0 1 1 1 0 CPSF A subunit region Ribosomal_L10 PF00466.15 EEB09627.1 - 2.4e-26 91.5 2.0 4.5e-26 90.6 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EEB09627.1 - 4.5e-18 65.4 7.2 4.5e-18 65.4 5.0 2.2 3 0 0 3 3 3 1 60s Acidic ribosomal protein WD40 PF00400.27 EEB09628.1 - 2.9e-10 39.5 4.2 5.1e-05 22.9 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Guanylate_kin PF00625.16 EEB09629.1 - 3.5e-66 222.1 0.0 4.1e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_17 PF13207.1 EEB09629.1 - 4.6e-06 27.4 0.0 7.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEB09629.1 - 5.2e-06 26.7 0.0 7.2e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EEB09629.1 - 6.1e-06 26.3 0.0 7.9e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EEB09629.1 - 6.5e-06 26.4 0.0 2.6e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEB09629.1 - 9.1e-06 25.8 0.0 6.1e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEB09629.1 - 1e-05 25.6 0.1 3.3e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EEB09629.1 - 1.5e-05 24.9 0.1 0.00016 21.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEB09629.1 - 1.6e-05 24.1 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EEB09629.1 - 9.4e-05 22.1 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA PF00004.24 EEB09629.1 - 0.00038 20.6 0.0 0.0007 19.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEB09629.1 - 0.00045 20.1 0.0 0.00081 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EEB09629.1 - 0.00076 19.4 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EEB09629.1 - 0.00081 19.1 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EEB09629.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 EEB09629.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EEB09629.1 - 0.0028 17.3 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Miro PF08477.8 EEB09629.1 - 0.005 17.3 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EEB09629.1 - 0.0054 16.7 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain PTS_IIB PF02302.12 EEB09629.1 - 0.0058 17.0 0.0 4 7.9 0.0 3.0 2 1 1 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit AAA_29 PF13555.1 EEB09629.1 - 0.0071 15.8 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EEB09629.1 - 0.0095 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEB09629.1 - 0.0096 15.5 0.4 0.051 13.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF1895 PF08988.5 EEB09629.1 - 0.024 14.6 0.1 0.055 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) MobB PF03205.9 EEB09629.1 - 0.028 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EEB09629.1 - 0.036 13.4 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEB09629.1 - 0.079 12.3 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Ras PF00071.17 EEB09629.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras family Septin PF00735.13 EEB09629.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.9 EEB09629.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Glyco_hydro_76 PF03663.9 EEB09630.2 - 5e-119 397.9 21.4 6.6e-119 397.5 14.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 EEB09631.1 - 4.1e-131 437.7 23.8 5.2e-131 437.4 16.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TFIIF_beta PF02270.10 EEB09632.1 - 8.2e-77 258.6 0.0 2.1e-52 178.6 0.0 2.2 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit WD40 PF00400.27 EEB09633.2 - 1e-28 98.1 11.0 2.4e-06 27.1 0.0 6.9 6 1 2 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EEB09633.2 - 2.8e-06 27.1 0.3 0.0057 16.3 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Sec23_trunk PF04811.10 EEB09634.1 - 7.6e-16 58.2 0.2 1.2e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEB09634.1 - 6.4e-10 38.3 0.0 1.8e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EEB09634.1 - 1.1e-09 37.6 4.1 4.4e-09 35.7 2.8 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EEB09634.1 - 2.2e-05 24.8 0.2 8e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.10 EEB09635.1 - 9.6e-40 136.4 0.3 1.5e-39 135.8 0.2 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEB09635.1 - 2.9e-13 49.1 2.8 1.1e-12 47.2 0.7 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEB09635.1 - 2e-09 37.8 0.1 3.8e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEB09635.1 - 2.5e-05 23.7 0.8 5e-05 22.7 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.1 EEB09635.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain TF_Zn_Ribbon PF08271.7 EEB09635.1 - 0.16 11.3 0.5 0.34 10.2 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Myb_DNA-binding PF00249.26 EEB09636.1 - 8.5e-21 73.7 13.1 1.8e-10 40.6 0.2 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEB09636.1 - 1.2e-19 70.1 12.0 2.5e-13 49.9 0.9 3.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EEB09636.1 - 0.057 13.5 0.7 0.057 13.5 0.5 4.1 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain tRNA-synt_2 PF00152.15 EEB09637.1 - 2e-69 233.9 0.0 3.5e-69 233.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEB09637.1 - 2.4e-09 36.8 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UQ_con PF00179.21 EEB09638.1 - 6.4e-41 139.0 0.0 7.4e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M20 PF01546.23 EEB09639.1 - 3.8e-30 104.7 0.0 6.4e-30 104.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEB09639.1 - 3.1e-16 59.1 0.0 6.6e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Trehalase PF01204.13 EEB09640.1 - 3.6e-189 629.6 0.9 4.5e-189 629.3 0.6 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EEB09640.1 - 1.9e-17 62.2 0.3 3.6e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain MIT PF04212.13 EEB09641.1 - 0.0029 17.4 1.9 0.0052 16.6 1.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Val_tRNA-synt_C PF10458.4 EEB09641.1 - 0.24 11.5 1.2 11 6.1 0.2 2.7 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm GTP_EFTU PF00009.22 EEB09643.2 - 4.4e-56 189.3 0.0 6.5e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEB09643.2 - 2.9e-22 78.3 0.0 5.5e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EEB09643.2 - 2.6e-15 56.0 0.0 1.8e-13 50.1 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEB09643.2 - 6.6e-05 22.9 1.3 0.00015 21.7 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEB09643.2 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEB09643.2 - 0.0023 18.4 0.0 0.0054 17.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RRM_1 PF00076.17 EEB09644.1 - 7.9e-28 95.9 0.5 1.5e-12 46.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09644.1 - 3.4e-21 74.9 0.0 3.6e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09644.1 - 1.3e-12 47.3 0.0 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2992 PF11208.3 EEB09644.1 - 6.7 6.6 17.0 14 5.5 11.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Glyco_hydro_cc PF11790.3 EEB09645.1 - 1.8e-59 201.1 2.5 2.5e-59 200.5 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.12 EEB09645.1 - 0.00076 17.9 0.0 0.0011 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 DUF566 PF04484.7 EEB09645.1 - 3 7.2 11.2 4.4 6.7 7.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 EEB09645.1 - 5.4 5.1 7.6 6.6 4.8 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein GHMP_kinases_N PF00288.21 EEB09646.1 - 2.2e-14 53.2 11.1 3.3e-14 52.7 4.7 3.0 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEB09646.1 - 2.5e-10 40.4 0.1 6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal AP_endonuc_2 PF01261.19 EEB09646.1 - 0.05 12.8 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel NMT1 PF09084.6 EEB09647.1 - 1.2e-73 247.2 0.0 1.5e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EEB09647.1 - 5.5e-06 25.9 0.0 0.00028 20.3 0.0 3.3 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 EEB09647.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 EEB09647.1 - 0.092 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 URO-D PF01208.12 EEB09647.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) VIT1 PF01988.14 EEB09648.1 - 3.8e-62 209.5 6.4 4.2e-62 209.3 4.5 1.0 1 0 0 1 1 1 1 VIT family RNA12 PF10443.4 EEB09648.1 - 0.004 15.6 0.1 0.017 13.6 0.0 1.8 2 0 0 2 2 2 1 RNA12 protein Chitin_synth_1 PF01644.12 EEB09649.1 - 3.6e-86 287.0 0.0 6e-86 286.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEB09649.1 - 2e-31 107.4 0.4 4.9e-31 106.2 0.3 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEB09649.1 - 1.2e-27 96.5 0.0 2.2e-21 75.8 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EEB09649.1 - 4.6e-11 42.9 0.0 3.1e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEB09649.1 - 2e-09 37.4 12.9 2e-09 37.4 8.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 NUDIX PF00293.23 EEB09650.1 - 2.4e-13 49.8 0.2 4.3e-13 49.0 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain Calcipressin PF04847.7 EEB09651.1 - 8.4e-27 93.9 0.0 9.8e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 EEB09651.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0029 PF01205.14 EEB09652.1 - 1.2e-29 102.2 0.2 2.2e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EEB09652.1 - 4.5e-09 36.2 0.8 1.4e-07 31.3 0.5 2.7 1 1 0 1 1 1 1 RWD domain EHN PF06441.7 EEB09652.1 - 0.18 11.7 3.2 0.48 10.3 2.2 1.7 1 1 0 1 1 1 0 Epoxide hydrolase N terminus YchF-GTPase_C PF06071.8 EEB09653.1 - 9.6e-37 124.6 0.1 2e-36 123.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EEB09653.1 - 1.9e-14 53.6 0.1 1e-13 51.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB09653.1 - 1.1e-05 24.7 0.0 3.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.1 EEB09653.1 - 0.011 15.6 0.0 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EEB09653.1 - 0.015 15.0 0.1 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EEB09653.1 - 0.033 12.9 0.0 0.063 12.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 EEB09653.1 - 0.09 13.0 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EEB09653.1 - 0.12 12.1 0.5 19 4.9 0.0 3.0 1 1 2 3 3 3 0 Dynamin family SSP160 PF06933.6 EEB09654.1 - 0.32 8.9 16.2 0.36 8.7 11.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Trp_oprn_chp PF09534.5 EEB09654.1 - 0.65 9.5 5.8 0.85 9.2 4.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Enamelin PF15362.1 EEB09654.1 - 7.7 4.4 5.9 7.9 4.4 4.1 1.0 1 0 0 1 1 1 0 Enamelin DNA_pol_E_B PF04042.11 EEB09655.2 - 7.7e-43 146.1 0.2 1.1e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CBFD_NFYB_HMF PF00808.18 EEB09657.2 - 1.7e-12 47.2 0.1 4.5e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEB09657.2 - 0.0003 20.8 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PsaN PF05479.6 EEB09657.2 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Bromo_TP PF07524.8 EEB09657.2 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated LSM PF01423.17 EEB09658.2 - 1.4e-14 53.4 0.6 2e-14 52.8 0.4 1.3 1 0 0 1 1 1 1 LSM domain PIGA PF08288.7 EEB09659.1 - 2.7e-45 152.6 1.5 1.1e-44 150.7 0.3 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EEB09659.1 - 3.1e-29 101.5 0.0 4.6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEB09659.1 - 4.3e-15 56.2 0.0 6.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EEB09659.1 - 9.3e-15 54.7 0.1 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEB09659.1 - 4.4e-14 52.7 0.0 7.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEB09659.1 - 0.00072 19.7 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyl_synth PF14572.1 EEB09660.1 - 3.1e-36 124.8 2.8 4.2e-32 111.3 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EEB09660.1 - 3.6e-34 116.9 0.1 1.7e-33 114.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EEB09660.1 - 7.4e-11 41.8 0.9 3.2e-10 39.7 0.7 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEB09660.1 - 0.00034 19.8 0.1 0.00056 19.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EEB09660.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain CTP_transf_1 PF01148.15 EEB09661.1 - 1.9e-20 73.6 6.9 2.7e-19 69.8 3.3 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family MAD PF05557.8 EEB09662.1 - 5.6e-75 252.8 78.5 6.5e-75 252.6 54.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.9 EEB09662.1 - 0.0038 16.8 29.4 0.0038 16.8 20.4 6.1 1 1 4 6 6 6 2 IncA protein bZIP_1 PF00170.16 EEB09662.1 - 0.016 15.1 2.4 0.016 15.1 1.7 11.5 9 4 5 14 14 14 0 bZIP transcription factor Reo_sigmaC PF04582.7 EEB09662.1 - 6.6 5.8 32.5 0.84 8.7 1.5 4.2 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Lactamase_B_2 PF12706.2 EEB09663.1 - 2.3e-32 112.0 0.2 4.4e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEB09663.1 - 2.5e-15 55.7 0.0 4.4e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEB09663.1 - 6.7e-10 38.9 0.0 4e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_4 PF12763.2 EEB09664.1 - 1e-27 95.9 0.0 3.3e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EEB09664.1 - 2.2e-21 75.6 333.7 0.00022 21.2 18.9 15.3 5 2 2 7 7 7 1 Domain of unknown function (DUF1720) WH2 PF02205.15 EEB09664.1 - 6.4e-08 31.9 0.1 1.3e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EEB09664.1 - 3.7e-06 26.9 0.1 0.00049 20.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEB09664.1 - 0.00025 20.1 0.0 3.6 7.1 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EEB09664.1 - 0.025 14.4 0.4 6.3 6.9 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain GAS PF13851.1 EEB09664.1 - 0.15 11.2 8.8 1.2 8.2 4.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.6 EEB09664.1 - 0.16 9.4 8.3 1.5 6.2 0.1 2.1 1 1 1 2 2 2 0 Prominin IncA PF04156.9 EEB09664.1 - 4.6 6.8 6.9 12 5.4 2.4 2.5 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 EEB09665.2 - 1.5e-40 138.3 40.7 2e-40 137.9 28.2 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EEB09665.2 - 7.3e-09 35.0 42.3 6.7e-06 25.3 19.5 2.9 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.7 EEB09665.2 - 5e-05 23.0 25.3 0.0086 15.8 6.4 2.6 1 1 1 2 2 2 2 Laminin Domain II KLRAQ PF10205.4 EEB09665.2 - 6.9e-05 22.8 27.0 0.00013 21.9 8.5 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Filament PF00038.16 EEB09665.2 - 9.6e-05 21.9 31.5 0.019 14.4 11.9 2.0 1 1 1 2 2 2 2 Intermediate filament protein PspA_IM30 PF04012.7 EEB09665.2 - 0.00011 21.6 30.7 0.0007 19.0 21.2 2.1 1 1 0 1 1 1 1 PspA/IM30 family GAS PF13851.1 EEB09665.2 - 0.00013 21.2 35.5 0.0026 16.9 17.0 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding FliJ PF02050.11 EEB09665.2 - 0.00045 20.2 12.9 0.00045 20.2 8.9 3.2 1 1 2 3 3 3 1 Flagellar FliJ protein BLOC1_2 PF10046.4 EEB09665.2 - 0.00064 19.8 25.6 0.11 12.6 5.0 3.4 1 1 2 3 3 3 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 EEB09665.2 - 0.00067 19.5 35.4 0.095 12.5 10.9 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 EEB09665.2 - 0.0012 18.5 36.7 0.022 14.4 16.3 2.7 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EEB09665.2 - 0.0021 17.7 39.2 0.11 12.0 27.0 2.2 1 1 0 1 1 1 1 IncA protein Phage_GP20 PF06810.6 EEB09665.2 - 0.0021 17.5 17.6 0.0021 17.5 12.2 2.4 1 1 1 2 2 2 1 Phage minor structural protein GP20 NPV_P10 PF05531.7 EEB09665.2 - 0.0028 17.8 16.7 0.24 11.6 5.3 2.8 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EEB09665.2 - 0.0028 17.6 39.4 0.0048 16.8 9.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EEB09665.2 - 0.0028 16.8 9.9 0.078 12.1 0.8 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF4201 PF13870.1 EEB09665.2 - 0.0029 17.0 18.3 0.0029 17.0 12.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) DUF4164 PF13747.1 EEB09665.2 - 0.0037 17.3 14.8 0.0037 17.3 10.3 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) DUF3584 PF12128.3 EEB09665.2 - 0.0039 14.6 34.0 0.0043 14.4 23.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fez1 PF06818.10 EEB09665.2 - 0.004 17.2 27.5 0.004 17.2 19.1 1.5 1 1 0 1 1 1 1 Fez1 FH2 PF02181.18 EEB09665.2 - 0.0044 15.9 8.1 0.0044 15.9 5.6 2.9 1 1 1 3 3 3 1 Formin Homology 2 Domain CENP-F_leu_zip PF10473.4 EEB09665.2 - 0.0052 16.6 42.2 0.0088 15.9 12.5 3.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 EEB09665.2 - 0.0054 16.2 26.1 0.0054 16.2 18.1 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 EEB09665.2 - 0.0086 14.5 30.2 0.017 13.6 20.9 1.5 1 1 0 1 1 1 1 AAA domain PilJ PF13675.1 EEB09665.2 - 0.0089 16.3 16.8 0.2 11.9 6.1 2.3 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term WXG100 PF06013.7 EEB09665.2 - 0.012 15.6 4.8 0.012 15.6 3.4 3.6 1 1 1 3 3 3 0 Proteins of 100 residues with WXG ADIP PF11559.3 EEB09665.2 - 0.013 15.4 34.4 0.18 11.7 10.9 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EEB09665.2 - 0.013 15.3 24.4 0.023 14.6 3.1 4.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EEB09665.2 - 0.013 14.1 35.4 0.06 11.9 10.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.6 EEB09665.2 - 0.014 15.2 17.6 0.3 10.9 2.6 3.1 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EEB09665.2 - 0.014 14.4 40.4 0.25 10.3 11.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF745 PF05335.8 EEB09665.2 - 0.016 14.7 24.2 0.11 11.9 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TelA PF05816.6 EEB09665.2 - 0.025 13.3 22.0 0.012 14.3 4.0 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF869 PF05911.6 EEB09665.2 - 0.026 12.7 33.0 0.16 10.1 1.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Snapin_Pallidin PF14712.1 EEB09665.2 - 0.037 14.3 24.6 0.26 11.6 10.0 3.1 1 1 2 3 3 3 0 Snapin/Pallidin AAA_27 PF13514.1 EEB09665.2 - 0.038 11.6 30.1 0.046 11.4 20.9 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.12 EEB09665.2 - 0.041 13.5 32.2 0.4 10.3 2.0 4.1 1 1 3 4 4 4 0 Prefoldin subunit Myosin_tail_1 PF01576.14 EEB09665.2 - 0.045 11.4 42.2 0.76 7.4 29.3 1.9 1 1 0 1 1 1 0 Myosin tail DUF3450 PF11932.3 EEB09665.2 - 0.046 12.9 28.5 0.13 11.5 11.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF148 PF02520.12 EEB09665.2 - 0.064 13.0 17.9 0.027 14.2 9.8 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 IFT57 PF10498.4 EEB09665.2 - 0.097 11.3 30.7 0.83 8.3 21.3 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Amdo_NSP PF12475.3 EEB09665.2 - 0.099 12.5 2.0 3.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Amdovirus non-structural protein Sec8_exocyst PF04048.9 EEB09665.2 - 0.11 12.1 19.8 1.2 8.7 11.3 2.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EEB09665.2 - 0.12 11.2 12.3 0.15 10.9 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) FemAB PF02388.11 EEB09665.2 - 0.13 10.9 26.2 0.38 9.3 4.0 2.0 1 1 1 2 2 2 0 FemAB family Laminin_I PF06008.9 EEB09665.2 - 0.13 11.5 30.4 0.13 11.5 13.8 2.3 1 1 1 2 2 2 0 Laminin Domain I CCDC155 PF14662.1 EEB09665.2 - 0.14 11.7 35.6 0.044 13.3 21.9 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 EEB09665.2 - 0.16 12.1 20.0 0.15 12.1 10.5 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.7 EEB09665.2 - 0.17 10.2 7.1 0.25 9.7 4.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFR_dimer PF04253.10 EEB09665.2 - 0.21 11.1 2.9 1.1 8.8 2.0 2.3 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain Vps5 PF09325.5 EEB09665.2 - 0.23 10.7 23.8 0.11 11.6 3.1 2.9 1 1 3 4 4 4 0 Vps5 C terminal like DUF4515 PF14988.1 EEB09665.2 - 0.25 11.0 31.3 0.012 15.3 15.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) TBPIP PF07106.8 EEB09665.2 - 0.34 10.4 31.7 0.15 11.5 15.8 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 EEB09665.2 - 0.36 11.2 25.1 0.38 11.1 1.8 3.8 1 1 3 4 4 4 0 SlyX Baculo_PEP_C PF04513.7 EEB09665.2 - 0.39 10.5 13.5 1.2 8.9 3.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 EEB09665.2 - 0.46 10.2 38.5 4.7 6.9 13.0 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 EEB09665.2 - 0.47 8.5 31.3 0.033 12.3 15.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DivIC PF04977.10 EEB09665.2 - 0.51 9.8 35.6 0.061 12.8 8.2 4.3 1 1 4 5 5 5 0 Septum formation initiator YlqD PF11068.3 EEB09665.2 - 0.52 10.3 24.7 0.036 14.1 11.7 2.4 1 1 2 3 3 3 0 YlqD protein MCPsignal PF00015.16 EEB09665.2 - 0.55 9.7 13.5 0.32 10.5 6.0 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain bZIP_1 PF00170.16 EEB09665.2 - 0.56 10.2 30.7 0.5 10.3 1.1 3.7 2 1 1 3 3 3 0 bZIP transcription factor DUF2968 PF11180.3 EEB09665.2 - 0.57 9.5 25.6 0.27 10.6 11.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Uds1 PF15456.1 EEB09665.2 - 0.61 10.0 30.2 1.7 8.6 7.3 2.9 1 1 2 3 3 3 0 Up-regulated During Septation Occludin_ELL PF07303.8 EEB09665.2 - 0.62 10.8 20.8 6.2 7.6 0.3 3.5 1 1 2 3 3 3 0 Occludin homology domain TMF_DNA_bd PF12329.3 EEB09665.2 - 0.74 9.6 44.7 0.3 10.9 19.4 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Vps53_N PF04100.7 EEB09665.2 - 0.75 8.4 18.5 1.7 7.3 12.1 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal Adeno_PIX PF03955.9 EEB09665.2 - 0.78 10.2 19.4 2.5 8.6 3.5 3.0 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) HGD-D PF06050.8 EEB09665.2 - 0.79 8.4 5.0 0.87 8.3 3.0 1.6 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3086 PF11285.3 EEB09665.2 - 0.79 8.4 14.1 2.2 7.0 9.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Allexi_40kDa PF05549.6 EEB09665.2 - 0.83 8.8 16.0 0.57 9.4 7.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4140 PF13600.1 EEB09665.2 - 0.87 10.0 30.5 1.8 9.0 4.4 3.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.16 EEB09665.2 - 0.9 9.8 29.9 6.1 7.1 7.0 2.4 1 1 1 2 2 2 0 Spectrin repeat RmuC PF02646.11 EEB09665.2 - 0.97 8.2 22.0 2.1 7.1 3.0 2.6 1 1 0 2 2 2 0 RmuC family Lectin_N PF03954.9 EEB09665.2 - 1.1 8.7 15.8 3.4 7.0 0.6 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Flagellin_C PF00700.16 EEB09665.2 - 1.3 9.2 11.8 0.37 10.9 1.7 3.3 2 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region Tup_N PF08581.5 EEB09665.2 - 1.4 9.2 28.0 0.73 10.0 5.7 3.3 2 1 1 3 3 3 0 Tup N-terminal WEMBL PF05701.6 EEB09665.2 - 1.4 7.2 40.0 3.5 5.9 19.0 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Gp58 PF07902.6 EEB09665.2 - 1.6 6.8 9.1 0.78 7.8 2.3 2.0 1 1 1 2 2 2 0 gp58-like protein Mnd1 PF03962.10 EEB09665.2 - 1.8 8.1 34.5 3.7 7.1 13.8 2.2 1 1 1 2 2 2 0 Mnd1 family FlxA PF14282.1 EEB09665.2 - 1.8 8.5 27.7 3.3 7.7 9.1 3.0 1 1 1 2 2 2 0 FlxA-like protein DUF1465 PF07323.7 EEB09665.2 - 1.9 8.0 20.1 0.12 11.9 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Atg14 PF10186.4 EEB09665.2 - 1.9 7.3 30.4 0.68 8.8 17.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Dak2 PF02734.12 EEB09665.2 - 2 8.0 5.6 0.36 10.4 0.4 2.0 1 1 1 2 2 2 0 DAK2 domain Cob_adeno_trans PF01923.13 EEB09665.2 - 2.2 8.0 18.3 1.3 8.7 4.8 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF812 PF05667.6 EEB09665.2 - 2.4 6.5 31.6 17 3.7 21.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) NDT80_PhoG PF05224.7 EEB09665.2 - 2.8 7.9 6.9 12 5.8 0.1 2.1 1 1 1 2 2 2 0 NDT80 / PhoG like DNA-binding family ParB PF08775.5 EEB09665.2 - 2.8 8.2 15.5 4.5 7.5 9.6 2.2 1 1 1 2 2 1 0 ParB family Ax_dynein_light PF10211.4 EEB09665.2 - 2.8 7.7 33.0 2.6 7.8 3.7 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain HSP70 PF00012.15 EEB09665.2 - 3 5.6 27.8 0.28 9.0 15.5 1.8 1 1 1 2 2 2 0 Hsp70 protein Prefoldin_2 PF01920.15 EEB09665.2 - 3.1 7.6 38.8 2.8 7.7 3.5 4.1 1 1 3 4 4 4 0 Prefoldin subunit DUF724 PF05266.9 EEB09665.2 - 3.4 7.2 31.6 3.5 7.2 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FliD_C PF07195.7 EEB09665.2 - 4 6.6 19.6 25 4.0 0.6 3.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Nsp1_C PF05064.8 EEB09665.2 - 4.5 6.9 24.6 1 9.0 7.0 2.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region Lebercilin PF15619.1 EEB09665.2 - 4.8 6.5 39.4 6.3 6.1 22.2 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ApoO PF09769.4 EEB09665.2 - 4.9 6.8 9.5 11 5.6 3.2 2.5 1 1 1 2 2 2 0 Apolipoprotein O Seryl_tRNA_N PF02403.17 EEB09665.2 - 5.1 7.1 34.8 2.5 8.1 10.4 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2146 PF10220.4 EEB09665.2 - 5.4 4.8 15.6 6.2 4.6 10.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CorA PF01544.13 EEB09665.2 - 5.5 5.9 21.7 2.1 7.3 1.3 3.1 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein COG2 PF06148.6 EEB09665.2 - 5.9 6.7 24.2 7.7 6.4 5.2 3.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Lip_prot_lig_C PF10437.4 EEB09665.2 - 6.3 6.5 6.7 8.6 6.1 0.2 3.1 1 1 2 3 3 3 0 Bacterial lipoate protein ligase C-terminus Dor1 PF04124.7 EEB09665.2 - 6.6 5.0 18.5 4.8 5.5 11.7 1.6 1 1 0 1 1 1 0 Dor1-like family HAP1_N PF04849.8 EEB09665.2 - 7.4 5.4 36.2 23 3.8 25.1 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CHASE3 PF05227.8 EEB09665.2 - 7.5 6.2 22.9 15 5.2 0.7 2.9 2 1 0 2 2 2 0 CHASE3 domain DUF489 PF04356.7 EEB09665.2 - 7.7 6.0 12.3 2.5 7.6 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) V_ATPase_I PF01496.14 EEB09665.2 - 8.1 4.1 28.4 1.8 6.3 6.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4298 PF14131.1 EEB09665.2 - 8.4 6.3 16.8 5 7.0 0.8 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4298) Prominin PF05478.6 EEB09665.2 - 8.5 3.7 18.4 47 1.3 12.6 2.1 1 1 0 1 1 1 0 Prominin CDC37_N PF03234.9 EEB09665.2 - 9.2 6.5 27.4 31 4.8 19.0 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1759 PF03564.10 EEB09665.2 - 9.8 5.9 13.2 1.5 8.5 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Proteasome PF00227.21 EEB09666.1 - 9.3e-37 126.1 0.0 1.1e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Inhibitor_I9 PF05922.11 EEB09667.1 - 0.15 12.6 0.0 0.42 11.2 0.0 1.8 1 1 0 1 1 1 0 Peptidase inhibitor I9 Trm112p PF03966.11 EEB09668.1 - 3.8e-20 72.0 0.1 4.6e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF3133 PF11331.3 EEB09668.1 - 0.15 11.6 0.8 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) PCI PF01399.22 EEB09669.1 - 2.6e-09 37.3 0.4 3.5e-08 33.6 0.0 2.5 2 1 0 2 2 2 1 PCI domain Cnd1 PF12717.2 EEB09669.1 - 0.0029 17.4 0.5 0.86 9.4 0.2 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HECT_2 PF09814.4 EEB09669.1 - 0.058 12.1 0.1 0.1 11.3 0.1 1.5 1 1 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Na_Ca_ex PF01699.19 EEB09670.1 - 2.1e-44 150.5 36.8 4.4e-24 84.6 5.9 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DPM2 PF07297.7 EEB09670.1 - 0.015 15.5 0.1 0.12 12.6 0.1 2.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MRP-L27 PF09809.4 EEB09671.1 - 4.4e-11 42.4 0.3 5.2e-11 42.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RNA_pol_L_2 PF13656.1 EEB09672.1 - 5.6e-25 86.5 0.2 7.5e-25 86.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEB09672.1 - 1.7e-11 43.0 0.0 2.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1410 PF07198.6 EEB09672.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) UreD PF01774.12 EEB09674.1 - 4.3e-49 166.8 0.0 5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Ribosomal_L18ae PF01775.12 EEB09675.1 - 4.4e-54 181.6 1.0 5.5e-54 181.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RRM_1 PF00076.17 EEB09676.1 - 5.9e-10 38.6 0.0 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09676.1 - 1.8e-08 34.1 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09676.1 - 1.3e-06 28.3 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB09676.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4130 PF13566.1 EEB09676.1 - 0.0068 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 PAPA-1 PF04795.7 EEB09676.1 - 3.3 8.4 11.8 0.31 11.7 2.0 2.8 3 0 0 3 3 3 0 PAPA-1-like conserved region ATP11 PF06644.6 EEB09677.1 - 4.4e-57 193.6 2.9 2.3e-56 191.2 2.0 1.8 1 1 0 1 1 1 1 ATP11 protein DNA_pol_viral_N PF00242.12 EEB09677.1 - 0.051 12.6 0.3 0.07 12.1 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain P53_tetramer PF07710.6 EEB09677.1 - 0.073 12.1 0.0 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 P53 tetramerisation motif eIF3_subunit PF08597.5 EEB09678.1 - 3.5e-42 144.6 26.1 4e-42 144.4 18.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit EF-hand_1 PF00036.27 EEB09679.1 - 8.3e-39 127.9 6.9 6e-10 37.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEB09679.1 - 1e-34 118.4 0.7 4e-18 65.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEB09679.1 - 6.5e-33 112.1 7.8 5.3e-14 51.5 0.0 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEB09679.1 - 7.6e-30 100.0 3.7 1.9e-09 36.6 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEB09679.1 - 1e-24 84.6 7.1 2e-05 23.7 0.0 4.5 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 EEB09679.1 - 3.7e-14 52.3 0.0 7.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEB09679.1 - 8.5e-09 35.0 1.0 0.0021 17.7 0.0 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEB09679.1 - 4.6e-06 26.6 0.0 0.011 15.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EEB09679.1 - 5.8e-05 22.9 0.2 0.00029 20.7 0.0 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EEB09679.1 - 0.00015 21.5 0.2 0.52 10.0 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EEB09679.1 - 0.00081 18.9 0.0 1.9 8.1 0.0 2.6 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) LNS2 PF08235.8 EEB09679.1 - 0.0027 17.3 0.1 1.5 8.3 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) DUF3349 PF11829.3 EEB09679.1 - 0.006 16.9 0.3 7.4 7.0 0.0 2.7 1 1 3 4 4 4 2 Protein of unknown function (DUF3349) Caleosin PF05042.8 EEB09679.1 - 0.0062 16.1 0.1 0.52 9.8 0.0 2.5 1 1 0 2 2 2 1 Caleosin related protein DUF2267 PF10025.4 EEB09679.1 - 0.0094 16.0 0.2 2.3 8.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) DUF1103 PF06513.6 EEB09679.1 - 0.03 13.7 0.4 0.039 13.3 0.3 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Vps53_N PF04100.7 EEB09680.1 - 8.5e-90 301.2 17.6 8.5e-90 301.2 12.2 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal AA_permease PF00324.16 EEB09681.1 - 4.5e-100 335.2 35.9 6.2e-100 334.7 24.4 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 EEB09681.1 - 8.8e-35 120.0 36.0 1.1e-34 119.6 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease Thioredoxin_6 PF13848.1 EEB09682.1 - 1.5e-06 28.1 0.0 0.084 12.6 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin-like domain YajC PF02699.10 EEB09682.1 - 0.11 12.1 0.5 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sugar_tr PF00083.19 EEB09683.1 - 1.4e-115 386.4 23.6 1.6e-115 386.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEB09683.1 - 5.6e-20 71.3 25.5 1.4e-14 53.5 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRA1 PF03208.14 EEB09683.1 - 0.17 11.2 4.3 0.068 12.5 0.2 2.4 2 0 0 2 2 2 0 PRA1 family protein Glyco_transf_15 PF01793.11 EEB09684.2 - 1.1e-38 132.9 9.3 1.5e-38 132.6 6.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sen15 PF09631.5 EEB09685.1 - 1.9e-28 98.6 0.0 2.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein TRA-1_regulated PF02343.11 EEB09685.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.4 2 0 0 2 2 2 1 TRA-1 regulated protein R03H10.4 BING4CT PF08149.6 EEB09686.1 - 1.4e-40 136.6 0.0 7.8e-38 127.8 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EEB09686.1 - 9.2e-10 38.0 0.0 2.3e-06 27.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEB09686.1 - 0.0001 21.2 0.0 0.00035 19.4 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 EEB09686.1 - 0.054 12.9 0.0 0.2 11.0 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain SNAP PF14938.1 EEB09687.1 - 3e-102 341.5 14.4 3.4e-102 341.3 10.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 EEB09687.1 - 0.00015 21.3 15.9 0.019 14.5 0.9 4.2 2 1 4 6 6 6 3 TPR repeat TRAPPC-Trs85 PF12739.2 EEB09687.1 - 0.0005 18.8 0.6 0.011 14.3 0.0 2.1 1 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Apc3 PF12895.2 EEB09687.1 - 0.016 15.3 6.2 0.86 9.7 0.2 3.1 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EEB09687.1 - 0.044 13.5 5.7 9.5 6.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEB09687.1 - 0.12 12.3 13.4 0.93 9.4 1.4 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEB09687.1 - 1.5 9.4 11.0 30 5.3 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09687.1 - 3.4 8.5 13.4 4.2 8.2 0.5 4.7 2 2 3 5 5 5 0 Tetratricopeptide repeat FNIP_N PF14636.1 EEB09688.1 - 0.01 16.3 0.0 0.38 11.2 0.0 2.8 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus RRM_1 PF00076.17 EEB09689.1 - 8.1e-24 83.0 0.0 8.1e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09689.1 - 3.2e-18 65.3 0.0 6.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09689.1 - 3.2e-17 62.2 0.0 9.8e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB09689.1 - 0.018 14.8 0.1 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ESCRT-II PF05871.7 EEB09690.1 - 4.5e-35 120.5 6.6 5.1e-35 120.4 4.6 1.0 1 0 0 1 1 1 1 ESCRT-II complex subunit FA_hydroxylase PF04116.8 EEB09691.2 - 1.1e-09 38.6 22.3 1.4e-09 38.3 14.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EEB09691.2 - 0.12 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.17 EEB09692.2 - 3.3e-38 129.1 0.1 5.9e-19 67.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09692.2 - 3.7e-30 103.7 0.2 1.5e-15 56.8 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09692.2 - 1.5e-16 59.9 0.0 6e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EEB09692.2 - 3.2e-12 46.5 0.4 2e-11 44.0 0.3 2.2 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EEB09692.2 - 0.004 16.9 0.0 0.039 13.7 0.0 2.5 2 1 0 2 2 2 1 RNA binding motif DUF3956 PF13104.1 EEB09692.2 - 0.037 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF2170 PF09938.4 EEB09692.2 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) zf-RING_2 PF13639.1 EEB09693.1 - 1.5e-13 50.2 5.5 2.9e-13 49.4 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEB09693.1 - 1.3e-08 34.8 1.4 3.8e-08 33.3 1.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEB09693.1 - 1.7e-08 34.0 3.3 3e-08 33.2 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEB09693.1 - 2.8e-08 33.6 5.9 6e-08 32.5 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB09693.1 - 7.7e-08 31.8 1.8 1.3e-07 31.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB09693.1 - 7.8e-07 28.6 4.4 1.6e-06 27.6 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEB09693.1 - 0.00014 21.6 3.7 0.0017 18.1 2.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CDC73 PF05179.9 EEB09693.1 - 0.0038 16.6 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family zf-RING_4 PF14570.1 EEB09693.1 - 0.0073 15.8 2.8 0.013 15.0 2.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EEB09693.1 - 0.02 14.4 3.4 0.047 13.2 2.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.24 EEB09693.1 - 0.028 14.0 2.7 0.056 13.1 1.9 1.5 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.7 EEB09693.1 - 0.031 13.4 0.4 0.062 12.4 0.2 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EEB09693.1 - 0.031 13.9 1.6 0.059 13.1 0.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EEB09693.1 - 0.033 14.2 3.9 0.065 13.2 2.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EEB09693.1 - 0.45 10.4 4.9 2.1 8.2 3.4 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EEB09693.1 - 0.6 10.1 3.5 1.2 9.1 2.4 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EEB09693.1 - 0.62 9.8 3.8 4.4 7.1 2.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EEB09693.1 - 1.1 9.2 6.3 13 5.8 4.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RNase_P_p30 PF01876.11 EEB09694.1 - 1.2e-48 164.1 0.0 1.7e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M1 PF01433.15 EEB09695.1 - 1.7e-15 57.0 0.1 7.7e-08 31.8 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M1 Imm20 PF15568.1 EEB09695.1 - 0.0081 16.0 0.1 0.08 12.8 0.0 2.2 2 0 0 2 2 2 1 Immunity protein 20 HEAT_2 PF13646.1 EEB09695.1 - 0.027 14.7 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Ribosomal_S19 PF00203.16 EEB09696.1 - 8e-24 83.0 0.1 1e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Dzip-like_N PF13815.1 EEB09697.1 - 1.9e-18 66.3 1.4 3e-18 65.7 1.0 1.3 1 1 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Gti1_Pac2 PF09729.4 EEB09698.1 - 1.6e-46 158.2 1.7 2.5e-46 157.6 0.3 2.0 2 1 0 2 2 2 1 Gti1/Pac2 family WD40 PF00400.27 EEB09699.1 - 2.9e-74 242.5 10.2 9.5e-12 44.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EEB09699.1 - 7.8e-20 70.8 7.3 1.4e-19 70.0 5.0 1.4 1 0 0 1 1 1 1 Tup N-terminal PD40 PF07676.7 EEB09699.1 - 2.9e-06 26.8 0.6 1.6 8.4 0.0 5.9 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EEB09699.1 - 6.6e-06 25.9 0.0 0.0062 16.2 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBP1_C PF15272.1 EEB09699.1 - 0.011 15.3 1.7 0.021 14.3 1.2 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Nbas_N PF15492.1 EEB09699.1 - 0.013 14.6 0.6 7 5.6 0.0 3.8 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EEB09699.1 - 0.015 13.6 0.4 0.04 12.2 0.2 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.7 EEB09699.1 - 0.042 11.6 0.0 0.31 8.8 0.0 2.1 1 1 1 2 2 2 0 IKI3 family GP120 PF00516.13 EEB09699.1 - 0.093 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 DUF919 PF06034.6 EEB09699.1 - 3.7 7.2 6.4 8.6 6.0 4.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PPTA PF01239.17 EEB09701.1 - 1.1e-40 135.3 11.9 6.1e-10 38.0 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 EEB09701.1 - 0.00024 20.4 1.7 0.38 10.2 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4219) DUF4458 PF14660.1 EEB09701.1 - 0.079 12.9 0.1 0.9 9.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) SSXRD PF09514.5 EEB09701.1 - 3 7.2 5.9 0.63 9.4 0.1 2.9 3 0 0 3 3 3 0 SSXRD motif Metallophos PF00149.23 EEB09702.1 - 5.2e-15 55.3 0.5 7.4e-15 54.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3384 PF11864.3 EEB09703.2 - 4.8e-59 200.0 17.2 5.8e-59 199.7 10.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EEB09703.2 - 1e-55 188.0 0.2 3.3e-55 186.3 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 EEB09703.2 - 2.6e-12 46.4 4.1 2.6e-12 46.4 2.8 3.2 2 1 1 3 3 3 1 Tuberin IU_nuc_hydro PF01156.14 EEB09704.2 - 4.4e-50 170.6 0.0 5.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase TPPII PF12580.3 EEB09705.1 - 9.3e-59 198.0 0.0 1.6e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 EEB09705.1 - 6.9e-49 166.4 0.3 1e-48 165.9 0.2 1.2 1 0 0 1 1 1 1 Subtilase family SLS PF14611.1 EEB09706.2 - 2.7e-35 121.7 0.7 5.5e-35 120.7 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Adap_comp_sub PF00928.16 EEB09708.1 - 9.9e-42 142.8 0.5 1.5e-41 142.2 0.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MMS22L_C PF14911.1 EEB09708.1 - 0.0059 15.7 0.1 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal Plus-3 PF03126.13 EEB09710.1 - 5e-33 113.3 0.0 1.6e-32 111.7 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain DUF342 PF03961.8 EEB09710.1 - 3.6 5.9 18.1 0.15 10.4 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RNA_pol_Rpb1_1 PF04997.7 EEB09711.1 - 6.7e-94 314.9 0.0 9.3e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EEB09711.1 - 9.3e-93 310.4 0.1 1.3e-92 309.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEB09711.1 - 6.7e-68 227.8 0.0 1.3e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEB09711.1 - 1.4e-40 138.6 0.0 3.2e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEB09711.1 - 6e-32 109.5 0.1 1.3e-31 108.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EEB09711.1 - 0.002 17.5 0.2 0.0045 16.4 0.2 1.6 1 0 0 1 1 1 1 InsA N-terminal domain EAP30 PF04157.11 EEB09714.1 - 3e-45 154.1 0.3 3.7e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Tex_N PF09371.5 EEB09714.1 - 0.037 13.3 0.4 0.086 12.1 0.3 1.5 1 1 0 1 1 1 0 Tex-like protein N-terminal domain RabGAP-TBC PF00566.13 EEB09716.1 - 1.2e-28 100.0 2.4 1.7e-28 99.5 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CN_hydrolase PF00795.17 EEB09717.1 - 2.1e-27 95.6 0.0 9.3e-27 93.5 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NOGCT PF08155.6 EEB09718.1 - 6.3e-28 96.2 0.2 1.4e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EEB09718.1 - 1.7e-27 95.0 0.5 3.2e-27 94.1 0.3 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EEB09718.1 - 6.3e-17 61.5 0.0 1.6e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB09718.1 - 9.7e-10 37.9 0.2 2e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEB09718.1 - 0.00012 22.5 0.3 0.00064 20.2 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EEB09718.1 - 0.0016 17.5 0.0 0.0016 17.5 0.0 2.4 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.18 EEB09718.1 - 0.0047 16.7 0.7 2 8.2 0.0 2.9 2 1 1 3 3 3 1 Dynamin family AAA_22 PF13401.1 EEB09718.1 - 0.0048 17.0 1.5 1.4 9.0 0.0 4.1 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 EEB09718.1 - 0.0085 15.2 0.0 0.12 11.6 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EEB09718.1 - 0.054 13.1 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EEB09718.1 - 0.085 12.4 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Lip_prot_lig_C PF10437.4 EEB09718.1 - 0.13 11.9 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus AAA_14 PF13173.1 EEB09718.1 - 0.36 10.7 4.0 3.7 7.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EEB09718.1 - 0.88 9.5 6.7 11 5.9 0.0 4.1 2 2 2 4 4 4 0 AAA ATPase domain AAA_18 PF13238.1 EEB09718.1 - 3.3 8.0 6.4 4.8 7.5 0.0 3.8 2 1 1 3 3 3 0 AAA domain RRM_1 PF00076.17 EEB09719.1 - 5.6e-07 29.0 0.0 1.5e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09719.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09719.1 - 1.6e-05 24.7 0.1 4.6e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EEB09719.1 - 0.067 13.4 0.0 0.21 11.8 0.0 1.9 1 1 0 1 1 1 0 RNA polymerase II-binding domain. LRR_3 PF07725.7 EEB09720.2 - 0.33 10.7 1.5 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat CDK2AP PF09806.4 EEB09720.2 - 2.3 8.4 7.9 4.1 7.5 5.5 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Coprogen_oxidas PF01218.13 EEB09721.1 - 1e-125 418.2 0.8 1.1e-125 418.0 0.6 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PAP_assoc PF03828.14 EEB09722.1 - 4e-16 58.7 0.1 8.8e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEB09722.1 - 0.00027 21.1 0.0 0.00053 20.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.4 EEB09722.1 - 0.028 13.9 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus FANCI_S4 PF14678.1 EEB09724.1 - 0.078 12.0 0.1 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 FANCI solenoid 4 TPR_2 PF07719.12 EEB09724.1 - 0.15 12.0 0.2 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 EEB09725.1 - 1.2e-13 50.4 0.0 2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09725.1 - 2.7e-10 40.0 0.0 4.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09725.1 - 3.8e-10 39.4 0.0 6.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEB09725.1 - 5.3e-05 22.9 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TBPIP PF07106.8 EEB09726.1 - 8.9e-43 145.7 11.6 1.1e-42 145.4 8.0 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EEB09726.1 - 2.1e-05 24.2 9.6 3.4e-05 23.5 6.6 1.5 1 1 0 1 1 1 1 Mnd1 family HTH_20 PF12840.2 EEB09726.1 - 0.00033 20.3 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Penicillinase_R PF03965.11 EEB09726.1 - 0.002 18.1 0.8 0.0061 16.6 0.0 2.0 1 1 1 2 2 2 1 Penicillinase repressor Snapin_Pallidin PF14712.1 EEB09726.1 - 0.0029 17.8 11.1 0.03 14.6 0.6 3.1 1 1 1 2 2 2 1 Snapin/Pallidin DASH_Dad2 PF08654.5 EEB09726.1 - 0.0081 16.1 2.5 0.016 15.1 1.8 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3450 PF11932.3 EEB09726.1 - 0.011 15.0 3.9 0.017 14.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PEP-utilisers_N PF05524.8 EEB09726.1 - 0.028 14.2 4.7 0.19 11.5 0.3 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Prefoldin_2 PF01920.15 EEB09726.1 - 0.053 13.2 12.2 1.1 9.0 2.5 2.5 1 1 1 2 2 2 0 Prefoldin subunit TrmB PF01978.14 EEB09726.1 - 0.056 13.1 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Reo_sigmaC PF04582.7 EEB09726.1 - 0.06 12.5 0.8 0.13 11.4 0.3 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Rrf2 PF02082.15 EEB09726.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator FlaC_arch PF05377.6 EEB09726.1 - 0.11 12.4 1.9 5.1 7.0 0.1 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 EEB09726.1 - 0.12 12.2 6.7 0.43 10.5 4.7 1.9 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EEB09726.1 - 0.14 11.7 13.2 0.33 10.5 9.1 1.6 1 1 0 1 1 1 0 IncA protein V-SNARE PF05008.10 EEB09726.1 - 0.14 12.3 3.7 2.3 8.4 0.5 2.6 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Seryl_tRNA_N PF02403.17 EEB09726.1 - 0.26 11.3 12.1 0.34 10.9 4.2 3.1 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Band_7 PF01145.20 EEB09726.1 - 0.29 11.0 2.6 0.96 9.3 1.8 1.8 1 1 0 1 1 1 0 SPFH domain / Band 7 family DUF972 PF06156.8 EEB09726.1 - 0.45 10.8 12.0 0.73 10.1 6.8 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF972) CorA PF01544.13 EEB09726.1 - 0.49 9.3 4.8 0.31 10.0 0.4 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 EEB09726.1 - 0.5 9.8 8.2 1.9 8.0 0.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Tnp_P_element PF12017.3 EEB09726.1 - 0.6 9.2 4.8 1.1 8.4 2.2 2.2 1 1 1 2 2 2 0 Transposase protein DUF342 PF03961.8 EEB09726.1 - 1 7.7 10.2 1.1 7.6 6.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 EEB09726.1 - 1.2 9.1 9.4 1.2 9.1 1.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family YscO PF07321.7 EEB09726.1 - 1.2 8.9 9.6 0.46 10.3 4.8 1.7 2 0 0 2 2 1 0 Type III secretion protein YscO bZIP_1 PF00170.16 EEB09726.1 - 1.3 9.0 6.2 2.5 8.1 1.9 2.8 1 1 1 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 EEB09726.1 - 1.5 9.2 5.2 0.78 10.2 0.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 EEB09726.1 - 1.7 8.9 4.7 2.9 8.2 1.4 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Erp_C PF06780.6 EEB09726.1 - 2.2 8.1 12.2 1.5 8.6 4.7 2.4 2 1 0 3 3 2 0 Erp protein C-terminus Phage_GP20 PF06810.6 EEB09726.1 - 2.4 7.5 12.6 4.3 6.7 7.7 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 Syntaxin-6_N PF09177.6 EEB09726.1 - 3.9 7.9 7.5 36 4.8 4.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc24 PF08286.6 EEB09726.1 - 5.4 6.7 11.3 8.6 6.0 2.7 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ALG3 PF05208.8 EEB09727.1 - 6.2e-128 427.1 28.0 7.2e-128 426.9 19.4 1.0 1 0 0 1 1 1 1 ALG3 protein Thioredoxin PF00085.15 EEB09728.1 - 2.6e-30 104.1 0.5 2.9e-30 104.0 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEB09728.1 - 9e-08 32.3 0.3 2.7e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEB09728.1 - 5.4e-07 29.6 0.1 2.5e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EEB09728.1 - 4.2e-05 23.2 0.1 4.8e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEB09728.1 - 0.00061 19.3 0.2 0.001 18.6 0.1 1.5 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EEB09728.1 - 0.00077 19.0 0.0 0.00089 18.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EEB09728.1 - 0.0046 16.9 0.1 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.1 EEB09728.1 - 0.015 15.3 0.4 4.2 7.3 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin DIM1 PF02966.11 EEB09728.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Ost4 PF10215.4 EEB09729.1 - 6.7e-11 41.4 1.7 7.5e-11 41.3 1.2 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase FixQ PF05545.6 EEB09729.1 - 0.082 12.5 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF3687 PF12459.3 EEB09729.1 - 0.19 10.9 1.3 0.23 10.7 0.9 1.4 1 1 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Steroid_dh PF02544.11 EEB09730.1 - 5.3e-13 48.9 4.6 5.3e-13 48.9 3.2 2.2 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase V-ATPase_H_N PF03224.9 EEB09731.1 - 5.2e-51 173.6 5.7 1.1e-50 172.5 3.1 2.1 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EEB09731.1 - 9.4e-45 151.3 1.2 4.5e-43 145.9 0.1 3.4 4 0 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.17 EEB09731.1 - 5.1e-06 26.1 3.3 0.009 16.0 0.0 4.7 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 EEB09731.1 - 2.8e-05 23.7 0.1 0.00083 19.0 0.0 3.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EEB09731.1 - 0.00026 20.2 0.7 0.0093 15.0 0.0 2.2 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 EEB09731.1 - 0.0009 19.4 0.0 0.031 14.5 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats Ric8 PF10165.4 EEB09731.1 - 0.05 12.4 0.1 0.12 11.1 0.1 1.7 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Sec39 PF08314.6 EEB09732.1 - 1.6e-58 198.2 18.8 5.9e-57 193.1 13.1 2.0 1 1 0 1 1 1 1 Secretory pathway protein Sec39 DUF1212 PF06738.7 EEB09733.1 - 3e-44 150.8 17.6 2.4e-43 147.8 0.4 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEB09733.1 - 3.5e-23 81.9 14.7 3.5e-23 81.9 10.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF485 PF04341.7 EEB09733.1 - 3.9 7.2 6.8 0.28 10.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PPR_2 PF13041.1 EEB09734.2 - 0.00057 19.8 0.1 0.35 10.8 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EEB09734.2 - 0.0017 18.4 0.7 18 5.9 0.0 4.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain Exo70 PF03081.10 EEB09735.1 - 2.2e-36 125.4 3.1 2.2e-36 125.4 2.1 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_FP PF03258.9 EEB09735.1 - 0.00083 18.5 1.1 0.0016 17.6 0.1 1.9 2 0 0 2 2 2 1 Baculovirus FP protein Laminin_II PF06009.7 EEB09735.1 - 0.0085 15.8 4.0 0.11 12.2 0.5 2.8 1 1 1 2 2 2 1 Laminin Domain II BAR PF03114.13 EEB09735.1 - 0.0099 15.4 2.9 0.013 15.0 0.4 2.1 2 0 0 2 2 2 1 BAR domain HTH_WhiA PF02650.9 EEB09735.1 - 0.049 14.0 0.7 0.61 10.5 0.1 2.8 1 1 1 2 2 2 0 WhiA C-terminal HTH domain LOH1CR12 PF10158.4 EEB09735.1 - 0.18 11.5 4.8 6.1 6.6 0.4 3.4 3 1 0 3 3 3 0 Tumour suppressor protein Med4 PF10018.4 EEB09735.1 - 1 8.7 3.4 1.7 7.9 1.4 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 EEB09735.1 - 2 8.2 12.8 1.7 8.4 3.4 3.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.1 EEB09735.1 - 2.5 8.1 9.3 0.67 10.0 1.1 3.4 3 1 1 4 4 4 0 Syntaxin-like protein DUF4297 PF14130.1 EEB09736.2 - 0.012 15.6 0.4 0.018 14.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) WD40 PF00400.27 EEB09737.1 - 2e-17 62.3 3.1 8e-06 25.5 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEB09737.1 - 0.013 14.9 0.0 18 4.8 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HAD PF12710.2 EEB09738.1 - 1.6e-14 54.5 0.1 2.1e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEB09738.1 - 2.5e-06 26.8 0.1 1.6e-05 24.1 0.1 2.1 1 1 1 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 EEB09738.1 - 0.00051 20.3 0.0 0.0013 18.9 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB09738.1 - 0.014 15.7 0.0 0.39 11.0 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase A_thal_3526 PF09713.5 EEB09738.1 - 0.084 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) She9_MDM33 PF05546.6 EEB09739.1 - 5e-75 251.6 12.2 7.6e-75 251.0 8.4 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EEB09739.1 - 0.02 14.4 0.1 0.053 13.0 0.1 1.7 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Thioredoxin_4 PF13462.1 EEB09739.1 - 0.66 9.9 3.9 0.34 10.8 0.8 1.8 2 0 0 2 2 2 0 Thioredoxin DRY_EERY PF09750.4 EEB09739.1 - 1 9.4 9.4 0.092 12.8 2.4 2.0 2 0 0 2 2 2 0 Alternative splicing regulator Clathrin PF00637.15 EEB09740.1 - 1.1e-09 37.9 6.3 2.3e-09 36.9 0.6 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS TPR_19 PF14559.1 EEB09740.1 - 0.018 15.3 2.4 36 4.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EEB09740.1 - 0.027 14.4 8.3 12 6.1 0.2 5.6 6 0 0 6 6 6 0 PPR repeat PPR_2 PF13041.1 EEB09740.1 - 0.035 14.0 3.3 24 4.9 0.0 4.4 5 0 0 5 5 5 0 PPR repeat family PPR_1 PF12854.2 EEB09740.1 - 0.054 12.9 4.3 3.4 7.2 0.0 3.1 3 0 0 3 3 3 0 PPR repeat zf-RING_2 PF13639.1 EEB09740.1 - 0.31 10.9 15.1 0.58 10.0 8.2 2.7 2 0 0 2 2 2 0 Ring finger domain TPR_12 PF13424.1 EEB09740.1 - 0.6 10.0 4.7 4.2 7.3 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EEB09740.1 - 0.94 9.5 14.5 0.29 11.1 7.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEB09740.1 - 3.9 7.6 10.2 0.38 10.8 3.6 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger LRR_4 PF12799.2 EEB09742.2 - 3.9e-39 131.6 50.7 1.7e-11 43.4 0.5 7.0 5 3 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEB09742.2 - 4.4e-20 71.2 40.8 6.8e-07 28.9 2.1 5.5 2 1 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.1 EEB09742.2 - 1.8e-16 60.2 39.0 2.8e-07 30.2 0.6 3.5 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.1 EEB09742.2 - 5e-14 50.7 38.4 0.24 11.5 0.1 10.7 5 3 5 10 10 10 7 Leucine Rich repeat LRR_1 PF00560.28 EEB09742.2 - 2.4e-13 48.0 44.5 0.026 14.4 0.2 11.1 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 EEB09742.2 - 8.8e-13 46.2 33.4 0.042 14.0 0.3 10.7 9 1 1 10 10 10 4 Leucine rich repeat DUF2322 PF10084.4 EEB09742.2 - 0.00046 19.8 1.8 9.4 6.0 0.0 4.7 3 2 2 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2322) Aurora-A_bind PF09041.5 EEB09742.2 - 0.009 15.7 0.9 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 Aurora-A binding HisKA_2 PF07568.7 EEB09742.2 - 0.029 14.1 0.2 0.63 9.9 0.0 3.2 3 1 1 4 4 4 0 Histidine kinase FNIP PF05725.7 EEB09742.2 - 0.044 13.7 3.8 1.6 8.7 0.0 4.5 2 1 2 4 4 4 0 FNIP Repeat Proteasome PF00227.21 EEB09743.2 - 2.4e-47 160.7 0.1 2.9e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pribosyltran_N PF13793.1 EEB09744.2 - 4.6e-41 139.2 0.0 8.9e-41 138.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEB09744.2 - 8.4e-07 28.9 0.1 1.1e-05 25.3 0.0 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Mus7 PF09462.5 EEB09745.1 - 3.1e-100 336.8 24.3 3.1e-100 336.8 16.9 1.8 2 0 0 2 2 2 1 Mus7/MMS22 family ketoacyl-synt PF00109.21 EEB09746.1 - 1.9e-21 76.6 0.1 3.6e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EEB09746.1 - 1.5e-20 74.0 0.0 3.9e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EEB09746.1 - 1.2e-16 60.5 0.0 2.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EEB09746.1 - 2.4e-10 40.2 0.0 8.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEB09746.1 - 2.3e-09 37.3 0.0 9e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEB09746.1 - 0.0011 18.6 0.0 0.0034 17.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Thiolase_N PF00108.18 EEB09746.1 - 0.0023 16.9 0.5 0.0058 15.6 0.2 1.7 1 1 1 2 2 2 1 Thiolase, N-terminal domain DUF676 PF05057.9 EEB09747.1 - 3.8e-53 180.0 0.0 5.9e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EEB09747.1 - 0.004 16.9 0.1 0.0083 15.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEB09747.1 - 0.0045 16.6 0.1 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EEB09747.1 - 0.0077 15.8 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein cwf21 PF08312.7 EEB09748.2 - 2.2e-13 49.8 2.7 4.5e-13 48.8 1.9 1.6 1 0 0 1 1 1 1 cwf21 domain DUF2252 PF10009.4 EEB09748.2 - 0.098 11.5 5.1 0.12 11.2 3.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4404 PF14357.1 EEB09748.2 - 0.38 11.2 2.8 0.46 10.9 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2407_C PF13373.1 EEB09748.2 - 0.46 10.4 4.0 0.72 9.7 2.7 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain DEAD PF00270.24 EEB09749.2 - 7.7e-46 155.6 0.0 1.5e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEB09749.2 - 9.2e-27 92.7 0.0 2.4e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEB09749.2 - 6.5e-07 29.3 0.0 2.3e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CATSPERD PF15020.1 EEB09749.2 - 0.16 9.9 0.1 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Per1 PF04080.8 EEB09750.1 - 4.5e-98 327.9 14.5 6.1e-98 327.5 10.1 1.1 1 0 0 1 1 1 1 Per1-like Bromo_TP PF07524.8 EEB09752.1 - 3.6e-18 65.0 0.3 5.6e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Bromodomain associated SNARE PF05739.14 EEB09753.1 - 3.1e-19 68.4 3.4 3.1e-19 68.4 2.4 2.7 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEB09753.1 - 2.1e-08 34.2 12.5 1.2e-07 31.8 1.3 2.6 2 2 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 EEB09753.1 - 0.00083 18.9 8.9 0.28 10.6 2.3 2.2 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain GRAS PF03514.9 EEB09753.1 - 0.0078 14.9 0.2 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 GRAS domain family DUF3671 PF12420.3 EEB09753.1 - 0.056 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function Use1 PF09753.4 EEB09753.1 - 0.057 12.8 6.7 0.09 12.1 4.6 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 COG5 PF10392.4 EEB09753.1 - 0.13 12.1 3.6 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Syntaxin_2 PF14523.1 EEB09753.1 - 0.22 11.5 15.7 1.1 9.3 0.5 3.0 1 1 3 4 4 4 0 Syntaxin-like protein Mer2 PF09074.5 EEB09753.1 - 1.4 8.7 9.8 38 4.1 6.8 2.1 1 1 0 1 1 1 0 Mer2 DUF2116 PF09889.4 EEB09753.1 - 2.1 8.2 4.0 4.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Striatin PF08232.7 EEB09753.1 - 2.5 8.4 7.9 0.94 9.7 2.7 2.3 2 1 0 2 2 2 0 Striatin family SlyX PF04102.7 EEB09753.1 - 6.2 7.2 10.6 6 7.3 1.1 2.7 2 1 0 2 2 2 0 SlyX DUF947 PF06102.7 EEB09754.2 - 9.6e-53 178.4 27.5 9.6e-53 178.4 19.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF947) Pkinase PF00069.20 EEB09755.1 - 4.7e-52 176.7 0.2 2.2e-51 174.5 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEB09755.1 - 4.4e-21 75.1 0.0 6.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEB09755.1 - 0.00065 19.4 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEB09755.1 - 0.016 14.5 0.1 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EEB09755.1 - 0.028 13.4 0.3 0.35 9.8 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family eIF-3c_N PF05470.7 EEB09757.1 - 4.1e-208 692.2 14.6 1.4e-169 565.0 2.3 3.5 2 2 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EEB09757.1 - 3e-13 50.0 0.0 1.6e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain Ribosomal_L10 PF00466.15 EEB09757.1 - 0.21 11.5 2.5 4.6 7.2 0.1 3.6 4 0 0 4 4 4 0 Ribosomal protein L10 Profilin PF00235.14 EEB09758.1 - 3.2e-39 133.7 0.0 3.5e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Profilin MFS_1 PF07690.11 EEB09759.1 - 1.6e-39 135.6 59.2 1.6e-39 135.6 41.1 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEB09759.1 - 2e-15 56.3 9.8 2e-15 56.3 6.8 3.5 3 1 2 5 5 5 1 Sugar (and other) transporter TRI12 PF06609.8 EEB09759.1 - 5.2e-15 54.6 27.1 6.7e-15 54.2 18.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMCO5 PF14992.1 EEB09759.1 - 0.21 10.7 1.1 5.5 6.0 0.2 2.2 2 0 0 2 2 2 0 TMCO5 family Neurensin PF14927.1 EEB09759.1 - 0.7 9.2 5.2 0.39 10.1 0.2 3.0 3 1 0 3 3 3 0 Neurensin Mito_carr PF00153.22 EEB09760.1 - 2.3e-60 200.3 0.8 7.8e-20 70.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF456 PF04306.8 EEB09760.1 - 0.065 13.2 0.3 9.2 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF456) DUF1250 PF06855.7 EEB09760.1 - 0.1 12.1 0.2 0.79 9.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1250) Ins_allergen_rp PF06757.8 EEB09761.2 - 0.055 12.9 0.3 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Asparaginase_2 PF01112.13 EEB09762.2 - 4.9e-34 117.4 0.0 2.2e-33 115.3 0.0 1.8 1 1 0 1 1 1 1 Asparaginase DUF3932 PF13068.1 EEB09762.2 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) PAP2 PF01569.16 EEB09763.1 - 1.2e-15 57.3 6.4 1.2e-15 57.3 4.4 3.0 2 1 1 3 3 3 1 PAP2 superfamily DUF1196 PF06709.6 EEB09763.1 - 0.07 13.0 0.4 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) HbrB PF08539.6 EEB09764.2 - 4.9e-16 58.9 1.4 8.2e-16 58.2 0.9 1.4 1 0 0 1 1 1 1 HbrB-like Aminotran_1_2 PF00155.16 EEB09765.1 - 1.6e-67 228.0 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEB09765.1 - 3.2e-05 23.1 0.0 5.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EEB09765.1 - 0.00068 18.0 0.0 0.0014 16.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EEB09765.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEB09765.1 - 0.012 14.4 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V PAPA-1 PF04795.7 EEB09766.1 - 1.4e-22 80.1 6.7 1.4e-22 80.1 4.7 3.6 4 0 0 4 4 4 1 PAPA-1-like conserved region Plasmodium_Vir PF05795.6 EEB09766.1 - 6.3 5.8 20.6 0.36 9.9 7.9 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SPX PF03105.14 EEB09767.1 - 5.1e-37 128.1 0.4 1e-36 127.1 0.3 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EEB09767.1 - 2.7e-07 30.3 10.6 2.7e-07 30.3 7.4 2.6 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEB09767.1 - 2e-06 27.4 10.7 2e-06 27.4 7.4 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEB09767.1 - 7.8e-06 25.4 8.0 7.8e-06 25.4 5.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB09767.1 - 1.6e-05 24.4 10.6 1.6e-05 24.4 7.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEB09767.1 - 6.5e-05 22.8 11.9 6.5e-05 22.8 8.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEB09767.1 - 0.0012 18.4 10.8 0.0012 18.4 7.5 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEB09767.1 - 0.011 15.4 3.7 0.021 14.6 1.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EEB09767.1 - 0.12 12.2 2.7 0.29 10.9 1.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EEB09767.1 - 0.64 9.7 15.0 0.086 12.5 6.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EEB09767.1 - 0.68 10.0 12.3 0.17 12.0 5.2 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger MbeD_MobD PF04899.7 EEB09767.1 - 1.7 8.5 7.3 0.88 9.5 0.4 3.0 3 1 0 3 3 2 0 MbeD/MobD like zf-RING_4 PF14570.1 EEB09767.1 - 4.1 7.0 13.8 0.042 13.4 2.3 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DnaJ PF00226.26 EEB09768.1 - 1.1e-20 73.0 0.0 3.7e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EEB09768.1 - 2.6e-08 33.7 4.7 2.6e-08 33.7 3.3 1.8 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEB09768.1 - 1.8e-06 27.9 5.2 4.2e-06 26.7 3.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EEB09768.1 - 0.0051 16.8 4.6 0.015 15.3 3.2 1.9 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CpXC PF14353.1 EEB09768.1 - 0.0076 16.2 1.1 0.0076 16.2 0.8 2.3 3 0 0 3 3 3 1 CpXC protein zf-C2H2 PF00096.21 EEB09768.1 - 0.013 15.8 5.5 0.013 15.8 3.8 1.9 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-FCS PF06467.9 EEB09768.1 - 0.07 12.7 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF4230 PF14014.1 EEB09768.1 - 0.085 12.7 4.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) zf-FPG_IleRS PF06827.9 EEB09768.1 - 0.096 12.3 0.1 0.28 10.8 0.1 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn_ribbon_2 PF12674.2 EEB09768.1 - 0.099 13.0 0.8 0.33 11.3 0.5 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-C2H2_4 PF13894.1 EEB09768.1 - 0.18 12.2 4.6 0.25 11.7 2.0 2.3 2 0 0 2 2 1 0 C2H2-type zinc finger DUF3133 PF11331.3 EEB09768.1 - 0.19 11.3 0.4 0.98 9.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) BHD_2 PF10404.4 EEB09768.1 - 0.56 10.5 6.2 2.6 8.4 0.6 2.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 zf-C2H2_6 PF13912.1 EEB09768.1 - 0.67 9.9 11.4 0.086 12.7 3.7 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger ATP-synt_E PF05680.7 EEB09768.1 - 1.6 8.7 9.8 0.41 10.6 3.3 2.6 2 0 0 2 2 2 0 ATP synthase E chain SpoIISA_toxin PF14171.1 EEB09768.1 - 1.8 7.7 6.7 0.48 9.6 0.4 2.2 1 1 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Rsa3 PF14615.1 EEB09769.1 - 6.5e-17 60.5 0.6 6.5e-17 60.5 0.4 1.7 2 0 0 2 2 2 1 Ribosome-assembly protein 3 IFT57 PF10498.4 EEB09769.1 - 0.04 12.6 1.8 0.035 12.8 0.6 1.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 RHH_1 PF01402.16 EEB09769.1 - 0.28 11.1 1.4 0.54 10.2 0.2 2.1 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family tRNA_m1G_MT PF01746.16 EEB09770.1 - 5.5e-45 153.2 0.9 9.1e-45 152.5 0.6 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase CBM_25 PF03423.8 EEB09770.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DNA_primase_S PF01896.14 EEB09771.1 - 1.9e-56 189.8 0.0 2.9e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Drc1-Sld2 PF11719.3 EEB09772.1 - 2e-40 139.1 24.3 3.8e-22 78.9 8.7 2.5 1 1 1 2 2 2 2 DNA replication and checkpoint protein Mmp37 PF09139.6 EEB09772.1 - 0.21 10.5 0.5 0.29 10.1 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial matrix Mmp37 TPR_11 PF13414.1 EEB09773.1 - 8.4e-57 188.7 29.1 3.1e-13 49.1 0.2 7.0 2 2 7 9 9 9 9 TPR repeat TPR_1 PF00515.23 EEB09773.1 - 2.3e-43 144.0 15.7 0.00015 21.1 0.0 10.6 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EEB09773.1 - 5.8e-40 132.0 21.1 1.7e-05 24.3 0.1 11.1 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 EEB09773.1 - 2.1e-24 85.2 20.0 3.3e-07 30.1 0.2 7.3 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEB09773.1 - 2.9e-24 85.1 15.5 2.7e-06 27.9 0.2 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEB09773.1 - 1.3e-22 78.0 6.8 0.0079 16.3 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEB09773.1 - 4.2e-20 70.4 10.5 0.082 13.5 0.0 10.3 5 4 6 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEB09773.1 - 8.9e-18 64.3 18.8 3.4e-05 24.0 0.9 7.7 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEB09773.1 - 1.7e-16 58.6 17.2 0.0047 16.6 0.0 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEB09773.1 - 2e-13 49.0 15.4 0.58 10.0 0.1 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EEB09773.1 - 2.1e-12 46.9 17.8 9.9e-05 22.4 0.1 5.5 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEB09773.1 - 6.5e-08 32.5 16.0 0.0029 17.9 0.0 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEB09773.1 - 3.6e-06 26.7 1.9 0.45 10.3 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEB09773.1 - 0.0015 17.7 1.5 2.4 7.4 0.1 4.3 4 0 0 4 4 4 1 SHNi-TPR TPR_10 PF13374.1 EEB09773.1 - 0.0031 17.3 14.9 7.5 6.6 0.0 6.8 7 1 1 8 8 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EEB09773.1 - 0.011 16.3 6.6 5.6 7.7 0.0 5.0 5 0 0 5 5 4 0 Sel1 repeat TPR_4 PF07721.9 EEB09773.1 - 0.03 14.7 11.8 24 5.7 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.15 EEB09773.1 - 0.09 12.7 1.4 70 3.7 0.0 4.7 4 0 0 4 4 4 0 PPR repeat LMBR1 PF04791.11 EEB09773.1 - 0.4 9.2 1.6 0.57 8.7 1.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 EEB09773.1 - 1.1 9.1 4.5 2.3 8.0 3.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S27e PF01667.12 EEB09774.1 - 7.1e-29 99.1 4.9 9.4e-29 98.7 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EEB09774.1 - 0.0078 16.0 1.6 0.0088 15.8 1.1 1.1 1 0 0 1 1 1 1 IBR domain FYVE_2 PF02318.11 EEB09774.1 - 0.094 12.6 1.3 0.11 12.3 0.9 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CSL PF05207.8 EEB09774.1 - 0.13 11.7 1.2 0.2 11.1 0.8 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF3133 PF11331.3 EEB09774.1 - 0.54 9.8 4.9 7.5 6.2 3.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) PPI_Ypi1 PF07491.6 EEB09775.1 - 1.5e-23 82.1 9.0 3.3e-23 81.0 6.3 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor Vpu PF00558.14 EEB09775.1 - 0.012 15.1 0.4 0.016 14.7 0.3 1.2 1 0 0 1 1 1 0 Vpu protein Treacle PF03546.9 EEB09775.1 - 0.047 12.4 1.8 0.055 12.2 1.3 1.0 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Rab_eff_C PF04698.7 EEB09775.1 - 0.062 11.4 2.9 0.071 11.2 2.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus FDF PF09532.5 EEB09775.1 - 0.37 11.3 3.9 0.76 10.3 2.7 1.6 1 1 0 1 1 1 0 FDF domain WD40 PF00400.27 EEB09776.1 - 9.7e-66 215.4 30.9 3.8e-14 51.9 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEB09776.1 - 1.8e-05 23.0 6.7 0.086 10.9 0.1 4.2 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEB09776.1 - 0.00055 18.3 0.0 0.79 7.9 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain DUF3601 PF12208.3 EEB09776.1 - 0.065 13.1 0.0 0.27 11.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3601) IKI3 PF04762.7 EEB09776.1 - 0.082 10.7 0.4 1.5 6.5 0.2 2.5 1 1 0 1 1 1 0 IKI3 family PD40 PF07676.7 EEB09776.1 - 0.13 11.9 0.6 36 4.1 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cellulase PF00150.13 EEB09777.1 - 4.8e-14 52.2 1.9 7.1e-14 51.6 1.3 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) OTOS PF15182.1 EEB09777.1 - 3.1 7.5 5.9 16 5.2 0.1 3.1 2 1 1 3 3 3 0 Otospiralin DUF4451 PF14616.1 EEB09778.2 - 2.6e-32 111.1 2.6 4.1e-32 110.5 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) eIF-5_eIF-2B PF01873.12 EEB09779.1 - 2e-46 156.7 0.3 3.1e-46 156.0 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EEB09779.1 - 0.0039 16.4 0.6 0.015 14.5 0.2 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Hid1 PF12722.2 EEB09779.1 - 0.028 12.1 14.4 0.034 11.8 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Arc_trans_TRASH PF08394.5 EEB09779.1 - 1.6 8.9 7.1 2.2 8.4 0.1 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain DUF4613 PF15390.1 EEB09779.1 - 2.4 6.2 8.2 2.9 5.9 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1708 PF08101.6 EEB09780.2 - 1.6e-52 178.7 0.3 1.3e-51 175.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) DUF4449 PF14613.1 EEB09781.2 - 3.6e-43 147.3 5.3 3.6e-43 147.3 3.6 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF4449) PBP_GOBP PF01395.17 EEB09781.2 - 0.053 13.1 0.6 0.15 11.6 0.4 1.7 1 0 0 1 1 1 0 PBP/GOBP family DUF1697 PF08002.6 EEB09781.2 - 0.055 13.4 1.0 0.31 11.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1697) Symplekin_C PF12295.3 EEB09781.2 - 0.39 10.5 4.6 0.36 10.7 0.2 2.9 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal Homeobox PF00046.24 EEB09782.2 - 8.5e-16 57.3 1.0 1.7e-15 56.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEB09782.2 - 0.013 15.2 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain Trp_syntA PF00290.15 EEB09783.1 - 2.6e-84 281.8 0.1 4.3e-84 281.0 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EEB09783.1 - 1.3e-46 159.2 0.3 2.2e-46 158.4 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTH2 PF01981.11 EEB09784.1 - 2.6e-45 152.8 0.1 4.5e-45 152.0 0.1 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.1 EEB09784.1 - 0.031 13.9 1.1 0.054 13.1 0.8 1.4 1 0 0 1 1 1 0 FAM176 family NADH-u_ox-rdase PF10785.4 EEB09784.1 - 0.075 13.2 0.1 0.44 10.8 0.0 2.1 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit CBF PF03914.12 EEB09784.1 - 0.11 11.9 0.4 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 CBF/Mak21 family U1snRNP70_N PF12220.3 EEB09785.1 - 2.1e-27 95.2 3.3 3.1e-27 94.7 2.3 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EEB09785.1 - 5.5e-17 61.1 0.0 8.6e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEB09785.1 - 3.4e-15 55.7 0.0 6.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEB09785.1 - 6.9e-09 35.4 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DCP2 PF05026.8 EEB09786.1 - 3.2e-36 123.1 1.3 6e-36 122.2 0.9 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EEB09786.1 - 6.8e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CobU PF02283.11 EEB09786.1 - 0.05 13.0 0.6 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF1454 PF07305.7 EEB09786.1 - 0.08 12.0 5.0 0.027 13.5 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1454) Miro PF08477.8 EEB09787.2 - 8.4e-05 23.0 0.6 0.00034 21.0 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 EEB09787.2 - 0.015 15.1 0.7 0.083 12.7 0.5 2.3 1 1 0 1 1 1 0 AAA domain Adaptin_binding PF10199.4 EEB09787.2 - 0.016 15.4 7.5 1.6 9.0 5.2 2.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PduV-EutP PF10662.4 EEB09787.2 - 0.034 13.6 0.1 0.075 12.5 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EEB09787.2 - 0.04 13.1 0.9 0.089 12.0 0.0 2.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Tetraspannin PF00335.15 EEB09787.2 - 0.054 12.7 0.6 0.075 12.2 0.4 1.2 1 0 0 1 1 1 0 Tetraspanin family MMR_HSR1 PF01926.18 EEB09787.2 - 0.065 13.2 0.1 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF1903 PF08991.5 EEB09787.2 - 0.099 12.8 0.5 0.39 10.9 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1903) zf-RING_5 PF14634.1 EEB09788.1 - 0.0002 21.0 5.6 0.00032 20.3 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEB09788.1 - 0.00061 19.5 3.6 0.00092 18.9 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEB09788.1 - 0.0012 18.8 2.0 0.0024 17.8 1.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEB09788.1 - 0.002 17.7 5.5 0.0036 16.9 3.8 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEB09788.1 - 0.036 13.7 5.4 0.068 12.8 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEB09788.1 - 0.048 13.3 2.4 0.56 9.9 2.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger IBR PF01485.16 EEB09788.1 - 0.4 10.5 6.3 0.94 9.4 3.0 2.1 1 1 1 2 2 2 0 IBR domain zf-RING_4 PF14570.1 EEB09788.1 - 0.9 9.1 7.3 4 7.1 5.3 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EEB09788.1 - 1.3 8.8 6.5 27 4.6 4.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon Yos1 PF08571.5 EEB09789.1 - 1.3e-27 95.6 0.7 1.4e-27 95.5 0.5 1.0 1 0 0 1 1 1 1 Yos1-like MIF4G PF02854.14 EEB09790.1 - 9.7e-45 152.5 19.4 5.1e-22 78.3 1.4 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EEB09790.1 - 7.4e-33 113.7 5.7 1.6e-32 112.5 3.9 1.6 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Oxidored_FMN PF00724.15 EEB09791.1 - 1.1e-66 225.1 0.0 1.5e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EEB09791.1 - 0.035 12.9 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) ICMT PF04140.9 EEB09792.1 - 2.3e-26 91.8 0.9 2.3e-26 91.8 0.7 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EEB09792.1 - 7.3e-14 51.7 1.1 7.3e-14 51.7 0.7 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EEB09792.1 - 0.00011 21.6 0.2 0.00011 21.6 0.1 1.6 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.7 EEB09792.1 - 0.00011 21.5 0.4 0.00018 20.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EEB09792.1 - 0.00047 18.8 0.4 0.00067 18.3 0.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family APG17 PF04108.7 EEB09793.1 - 1.3e-69 234.9 18.8 3.2e-69 233.7 13.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg17 MazG PF03819.12 EEB09793.1 - 0.0014 18.5 0.1 0.0067 16.3 0.0 2.3 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MutS_III PF05192.13 EEB09793.1 - 0.0035 17.1 2.0 0.0035 17.1 1.4 2.3 1 1 1 2 2 2 1 MutS domain III DUF1825 PF08855.5 EEB09793.1 - 0.096 12.6 7.0 0.41 10.6 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) DUF3391 PF11871.3 EEB09793.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Phage_min_cap2 PF06152.6 EEB09793.1 - 0.15 11.0 5.5 0.023 13.6 0.4 1.9 2 1 0 2 2 2 0 Phage minor capsid protein 2 Filament PF00038.16 EEB09793.1 - 0.57 9.5 18.7 5.2 6.4 12.7 2.4 1 1 0 1 1 1 0 Intermediate filament protein Hemerythrin PF01814.18 EEB09793.1 - 0.66 10.1 13.7 1.1 9.4 2.2 4.4 2 2 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF2203 PF09969.4 EEB09793.1 - 1.1 9.5 11.8 1.8 8.7 0.3 3.4 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) VBS PF08913.5 EEB09793.1 - 1.2 9.4 6.6 6.8 6.9 0.1 3.8 3 2 1 4 4 4 0 Vinculin Binding Site DUF3347 PF11827.3 EEB09793.1 - 4.6 7.2 10.8 0.37 10.7 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) SF-assemblin PF06705.6 EEB09793.1 - 9.6 5.2 12.9 0.39 9.8 0.2 3.5 3 1 1 4 4 4 0 SF-assemblin/beta giardin RIO1 PF01163.17 EEB09794.1 - 4.6e-75 251.1 0.0 4.6e-75 251.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EEB09794.1 - 2.8e-06 27.2 0.1 0.0017 18.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEB09794.1 - 0.00013 21.1 0.4 0.0017 17.4 0.3 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.9 EEB09794.1 - 0.18 9.8 19.5 0.31 9.0 13.5 1.4 1 0 0 1 1 1 0 CDC45-like protein D123 PF07065.9 EEB09794.1 - 0.69 8.9 8.2 0.12 11.4 2.6 1.9 1 1 1 2 2 2 0 D123 Herpes_DNAp_acc PF04929.7 EEB09794.1 - 2.4 7.0 11.8 3.9 6.3 8.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SMC_N PF02463.14 EEB09795.1 - 3e-65 219.5 0.0 4.9e-65 218.8 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEB09795.1 - 1.5e-32 112.0 0.0 9.3e-32 109.5 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEB09795.1 - 6e-11 42.8 10.7 1.9e-05 24.7 0.0 3.9 5 0 0 5 5 5 2 AAA domain AAA_23 PF13476.1 EEB09795.1 - 0.00013 22.3 42.9 0.00013 22.3 29.7 6.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEB09795.1 - 0.0019 17.6 0.0 0.0053 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.7 EEB09796.1 - 0.0018 18.0 1.5 0.0036 17.0 1.1 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Lge1 PF11488.3 EEB09796.1 - 0.015 15.4 1.1 0.025 14.7 0.7 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF4200 PF13863.1 EEB09796.1 - 0.053 13.4 8.2 0.072 13.0 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EEB09796.1 - 0.054 11.3 0.2 0.05 11.4 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EEB09796.1 - 0.06 13.7 1.3 0.079 13.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 EEB09796.1 - 0.077 13.0 2.9 0.094 12.8 1.6 1.5 1 1 0 1 1 1 0 Central kinetochore-associated DUF4140 PF13600.1 EEB09796.1 - 0.15 12.5 3.3 0.14 12.6 1.3 1.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phlebovirus_NSM PF07246.6 EEB09796.1 - 0.16 11.0 0.8 0.19 10.8 0.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF724 PF05266.9 EEB09796.1 - 0.19 11.2 3.5 0.26 10.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 EEB09796.1 - 0.33 9.9 2.6 0.43 9.5 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EEB09796.1 - 0.36 9.4 3.8 0.47 9.0 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EEB09796.1 - 0.75 8.6 6.7 0.95 8.3 4.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EEB09796.1 - 1.9 8.0 5.2 2.7 7.6 3.6 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EEB09796.1 - 2.6 7.6 6.4 5.3 6.6 3.6 1.9 1 1 1 2 2 2 0 Septum formation initiator RRM_6 PF14259.1 EEB09797.1 - 2.1e-08 33.9 0.0 4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEB09797.1 - 7.2e-08 31.9 0.1 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.5 EEB09797.1 - 0.14 11.2 3.1 0.12 11.3 0.6 1.8 2 0 0 2 2 2 0 BUD22 UQ_con PF00179.21 EEB09798.2 - 3.7e-27 94.4 0.8 8.3e-27 93.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEB09798.2 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain RCC1 PF00415.13 EEB09799.1 - 3.4e-27 94.3 18.8 2.3e-11 43.7 0.1 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEB09799.1 - 7.7e-19 66.7 21.9 3.6e-07 29.6 0.3 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat CTP_synth_N PF06418.9 EEB09800.2 - 3.6e-105 351.0 0.3 4.8e-105 350.5 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEB09800.2 - 1.1e-55 188.0 0.0 1.7e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEB09800.2 - 8.5e-06 25.3 0.0 2.4e-05 23.9 0.0 1.7 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 EEB09800.2 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain S1 PF00575.18 EEB09801.2 - 1e-15 57.5 1.2 2.1e-15 56.5 0.8 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EEB09801.2 - 2.7e-09 36.7 0.2 5.5e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEB09801.2 - 7.1e-06 26.1 0.2 2.2e-05 24.6 0.1 2.0 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EEB09801.2 - 0.001 19.3 7.9 0.018 15.3 0.2 3.7 3 1 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 EEB09801.2 - 0.0012 18.5 0.1 0.0031 17.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EEB09801.2 - 0.006 15.5 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EEB09801.2 - 0.011 15.5 0.1 0.13 12.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EEB09801.2 - 0.014 14.8 0.3 0.03 13.7 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EEB09801.2 - 0.018 14.9 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EEB09801.2 - 0.019 14.2 0.1 0.094 11.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.9 EEB09801.2 - 0.035 13.8 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Sigma54_activ_2 PF14532.1 EEB09801.2 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EEB09801.2 - 0.055 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EEB09801.2 - 0.27 11.0 4.7 1.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit NIR_SIR PF01077.17 EEB09802.1 - 1.5e-48 164.1 0.0 3.8e-43 146.5 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EEB09802.1 - 3.6e-29 100.1 0.0 4.1e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EEB09802.1 - 1.2e-26 93.3 0.0 3.5e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin POR_N PF01855.14 EEB09802.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HAD_2 PF13419.1 EEB09804.2 - 2.1e-19 70.4 0.0 2.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEB09804.2 - 3.3e-11 44.0 0.0 4.1e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEB09804.2 - 6.9e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EEB09804.2 - 0.00084 19.1 0.1 0.29 11.0 0.0 2.6 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EEB09804.2 - 0.039 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Ras PF00071.17 EEB09805.2 - 4.8e-60 201.6 0.3 6.1e-60 201.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEB09805.2 - 7.7e-21 74.8 0.1 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEB09805.2 - 1.1e-15 57.3 0.2 1.4e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEB09805.2 - 2e-07 30.6 0.0 9.1e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEB09805.2 - 1.2e-06 27.8 0.1 1.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEB09805.2 - 1.4e-06 27.6 0.6 1.6e-06 27.4 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEB09805.2 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEB09805.2 - 0.00039 19.7 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEB09805.2 - 0.0057 16.4 0.6 1.9 8.2 0.0 3.2 3 1 0 3 3 3 1 Dynamin family PduV-EutP PF10662.4 EEB09805.2 - 0.014 14.8 1.2 0.14 11.6 0.4 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EEB09805.2 - 0.042 13.5 0.0 0.073 12.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EEB09805.2 - 0.051 13.7 0.0 0.62 10.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain PQ-loop PF04193.9 EEB09806.1 - 6.6e-09 35.1 2.2 6.6e-09 35.1 1.6 3.8 3 2 0 3 3 3 2 PQ loop repeat ThiF PF00899.16 EEB09807.1 - 3.2e-12 46.4 0.0 4.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family adh_short PF00106.20 EEB09808.2 - 9.2e-29 100.4 0.7 1.2e-28 100.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEB09808.2 - 8.4e-27 94.4 1.0 1e-26 94.1 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEB09808.2 - 1.4e-12 47.6 0.4 1.9e-12 47.2 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEB09808.2 - 1.6e-06 27.7 0.4 3.3e-06 26.7 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Spore_IV_A PF09547.5 EEB09808.2 - 0.00025 19.8 0.0 0.00037 19.3 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) NmrA PF05368.8 EEB09808.2 - 0.0015 17.8 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EEB09808.2 - 0.0026 17.5 0.2 0.0076 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RLAN PF14401.1 EEB09808.2 - 0.0027 17.2 0.0 0.0074 15.8 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATPgrasp N-terminal domain THF_DHG_CYH_C PF02882.14 EEB09808.2 - 0.01 14.8 0.0 0.027 13.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EEB09808.2 - 0.015 15.3 0.6 0.03 14.3 0.4 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EEB09808.2 - 0.036 12.7 0.4 0.045 12.4 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family OmpH PF03938.9 EEB09808.2 - 0.049 13.5 0.1 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IcmL PF11393.3 EEB09808.2 - 0.064 13.2 0.3 0.79 9.6 0.0 2.5 1 1 1 2 2 2 0 Macrophage killing protein with similarity to conjugation protein 3HCDH_N PF02737.13 EEB09808.2 - 0.11 12.0 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_8 PF14716.1 EQC52955.1 - 7.7e-12 45.2 0.2 2.4e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain Helicase_C PF00271.26 EQC52957.1 - 2.6e-14 52.8 0.0 4.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Inhibitor_I29 PF08246.7 EQC52957.1 - 0.1 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Chromo PF00385.19 EQC52958.1 - 2.8e-11 42.9 2.4 3.5e-11 42.6 1.7 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LKAAEAR PF15478.1 EQC52959.1 - 0.11 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif HMG_box PF00505.14 EQC52960.1 - 0.7 10.2 2.9 0.53 10.5 0.3 1.8 1 1 1 2 2 2 0 HMG (high mobility group) box zf-CCHC PF00098.18 EQC52961.1 - 2.3e-06 27.2 3.1 4.3e-06 26.3 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EQC52961.1 - 0.12 12.1 2.4 0.22 11.2 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DEC-1_N PF04625.8 EQC52961.1 - 2.6 6.6 5.4 3.4 6.2 3.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retrotrans_gag PF03732.12 EQC52962.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein Vma12 PF11712.3 EQC52963.1 - 4.2e-16 58.9 0.0 5.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4536 PF15055.1 EQC52968.1 - 1.8e-07 31.0 1.2 3.4e-07 30.2 0.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) LSM PF01423.17 EQC52970.1 - 5.2e-06 25.9 0.0 6.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain UPF0203 PF05254.7 EQC52971.1 - 1.1e-24 86.0 2.9 1.1e-24 86.0 2.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 EQC52971.1 - 5.4e-05 22.9 2.8 0.00055 19.7 0.4 2.1 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 EQC52971.1 - 0.00054 19.6 3.3 0.31 10.8 0.3 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EQC52971.1 - 0.0049 16.7 1.4 1.7 8.6 0.1 2.0 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 EQC52971.1 - 0.036 14.1 2.9 0.18 11.8 2.0 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 EQC52971.1 - 0.058 13.5 0.9 0.058 13.5 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Pet191_N PF10203.4 EQC52971.1 - 0.11 12.5 0.6 9.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EQC52971.1 - 0.16 11.9 6.6 3.2 7.8 0.5 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.8 EQC52971.1 - 1.2 8.5 4.3 9.3 5.7 0.3 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-CCHC_3 PF13917.1 EQC52972.1 - 7.5e-18 63.9 4.1 1.5e-17 63.0 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M16 PF00675.15 EQC52972.1 - 0.074 12.8 0.3 0.092 12.4 0.2 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) FGGY_N PF00370.16 EQC52972.1 - 0.14 11.4 0.1 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Zn_ribbon_2 PF12674.2 EQC52972.1 - 0.24 11.7 3.5 0.5 10.7 2.4 1.7 1 1 0 1 1 1 0 Putative zinc ribbon domain DUF1682 PF07946.9 EQC52972.1 - 0.32 9.8 5.8 0.39 9.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Colicin-DNase PF12639.2 EQC52972.1 - 0.32 11.2 1.7 0.48 10.6 1.2 1.3 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin PPR_2 PF13041.1 EQC52973.1 - 0.041 13.8 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family PPR_1 PF12854.2 EQC52973.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PPR repeat Ribosomal_L31 PF01197.13 EQC52974.1 - 8e-05 22.5 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 Gp_dh_C PF02800.15 EQC52976.1 - 9.9e-75 249.2 0.1 1.4e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EQC52976.1 - 1.5e-61 206.8 0.1 2.6e-61 206.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EQC52976.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EQC52976.1 - 0.027 14.3 1.7 0.079 12.8 0.3 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EQC52976.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EQC52977.1 - 9e-75 249.3 0.1 1.4e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EQC52977.1 - 1.2e-62 210.3 0.1 2.1e-62 209.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EQC52977.1 - 0.0042 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EQC52977.1 - 0.033 14.0 2.2 0.093 12.6 0.5 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-UDP PF14569.1 EQC52978.1 - 0.17 11.6 10.2 0.35 10.6 7.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.11 EQC52978.1 - 0.6 10.0 10.2 0.86 9.5 7.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PolC_DP2 PF03833.8 EQC52978.1 - 1.2 6.7 7.2 1.3 6.6 5.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 COX7a PF02238.10 EQC52980.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Chorein_N PF12624.2 EQC52983.1 - 3.6e-32 110.3 0.0 1.3e-31 108.5 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DNase-RNase PF02577.9 EQC52983.1 - 0.16 11.2 0.5 6 6.0 0.0 2.5 2 0 0 2 2 2 0 Bifunctional nuclease NUFIP1 PF10453.4 EQC52984.1 - 1.5e-14 53.1 6.9 1.5e-14 53.1 4.7 2.9 3 1 1 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EQC52984.1 - 0.011 15.4 3.5 0.022 14.4 2.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nop25 PF09805.4 EQC52984.1 - 2.5 8.1 20.3 0.5 10.4 4.2 2.5 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) APC_CDC26 PF10471.4 EQC52984.1 - 5.2 7.8 24.6 0.94 10.2 2.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Methyltransf_23 PF13489.1 EQC52986.1 - 1.8e-15 57.0 0.0 4.7e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EQC52986.1 - 1.8e-06 27.2 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EQC52986.1 - 9.5e-05 22.8 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EQC52986.1 - 0.00024 21.6 0.0 0.00037 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EQC52986.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 EQC52986.1 - 0.026 14.8 0.0 0.051 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DCP1 PF06058.8 EQC52987.1 - 2e-22 79.5 0.1 2.3e-22 79.3 0.1 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family DUF3760 PF12586.3 EQC52988.1 - 0.18 11.6 1.7 0.68 9.8 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3760) Vma12 PF11712.3 EQC52989.1 - 4.3 7.0 5.9 0.5 10.0 0.5 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ABC2_membrane_3 PF12698.2 EQC52990.1 - 0.0027 16.8 0.1 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1242 PF06842.7 EQC52991.1 - 2.7e-19 68.3 1.5 4e-19 67.8 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.8 EQC52991.1 - 0.21 11.5 0.2 0.21 11.5 0.1 1.5 2 0 0 2 2 2 0 LST-1 protein DUF2373 PF10180.4 EQC52992.1 - 0.0054 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DAD PF02109.11 EQC52993.1 - 0.042 13.9 3.2 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 DAD family DUF1049 PF06305.6 EQC52993.1 - 0.25 10.8 4.7 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Vma12 PF11712.3 EQC52994.1 - 2.6 7.7 5.3 0.54 9.9 0.6 1.9 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pribosyltran PF00156.22 EQC52996.1 - 1.5e-10 40.8 0.4 2.7e-09 36.8 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 EQC52996.1 - 0.068 11.7 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ALS_ss_C PF10369.4 EQC52997.1 - 5.2e-20 70.9 0.0 2.6e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EQC52997.1 - 1e-10 40.8 0.2 2.4e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EQC52997.1 - 1e-09 38.0 0.1 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain Peptidase_M24 PF00557.19 EQC52998.1 - 8.7e-46 156.1 0.1 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SART-1 PF03343.8 EQC52998.1 - 0.011 14.0 7.1 0.014 13.7 4.9 1.1 1 0 0 1 1 1 0 SART-1 family Nucleoporin2 PF04096.9 EQC52999.1 - 0.076 12.8 0.4 0.09 12.5 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin autopeptidase PHA-1 PF06542.6 EQC52999.1 - 0.082 11.6 1.3 0.091 11.4 0.9 1.0 1 0 0 1 1 1 0 Regulator protein PHA-1 Helicase_C PF00271.26 EQC53000.1 - 1.7e-14 53.3 0.0 2.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vsr PF03852.10 EQC53000.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Inhibitor_I29 PF08246.7 EQC53000.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) AA_permease_2 PF13520.1 EQC53001.1 - 9.6e-55 185.8 53.1 1.2e-54 185.5 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EQC53001.1 - 2.7e-13 49.1 44.8 3.6e-13 48.6 31.1 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.8 EQC53001.1 - 0.15 9.9 7.7 0.26 9.1 5.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Zn_clus PF00172.13 EQC53002.1 - 8.2e-07 28.8 14.2 2e-06 27.5 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF4G PF02854.14 EQC53004.1 - 9.1e-33 113.4 0.2 1.9e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EQC53004.1 - 3.2e-27 94.4 0.5 9.2e-27 92.9 0.2 1.9 2 0 0 2 2 2 1 MA3 domain DUF1466 PF07326.6 EQC53005.1 - 0.048 12.9 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) OSTMP1 PF09777.4 EQC53005.1 - 0.15 11.1 0.2 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor SR-25 PF10500.4 EQC53005.1 - 1.7 8.0 6.3 1.9 7.9 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_C48 PF02902.14 EQC53007.1 - 1.3e-43 149.1 0.0 3e-43 147.9 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MRP_L53 PF10780.4 EQC53008.1 - 2.1e-11 43.6 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF716 PF04819.7 EQC53009.1 - 0.0018 17.7 2.0 0.0022 17.4 1.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF716) DUF1772 PF08592.6 EQC53009.1 - 0.033 13.9 0.1 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) PIG-P PF08510.7 EQC53009.1 - 0.053 13.1 2.6 0.058 13.0 1.8 1.1 1 0 0 1 1 1 0 PIG-P ATP-synt_8 PF00895.15 EQC53009.1 - 0.058 13.5 1.4 0.058 13.5 0.9 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4131 PF13567.1 EQC53009.1 - 0.16 11.3 1.6 0.16 11.3 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Complex1_LYR_1 PF13232.1 EQC53010.1 - 0.011 15.9 2.5 0.016 15.3 1.7 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EQC53010.1 - 0.037 14.4 0.5 0.046 14.2 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.10 EQC53010.1 - 0.05 13.3 3.5 0.098 12.4 2.4 1.6 1 1 0 1 1 1 0 Complex 1 protein (LYR family) rRNA_proc-arch PF13234.1 EQC53011.1 - 4.7e-83 278.4 0.1 4.7e-83 278.4 0.1 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EQC53011.1 - 2.3e-65 219.2 1.7 3.6e-65 218.5 0.1 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EQC53011.1 - 4.9e-22 78.2 0.0 3.2e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EQC53011.1 - 5.8e-07 29.2 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EQC53011.1 - 0.0069 15.3 0.0 0.019 13.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein UbiA PF01040.13 EQC53016.1 - 3e-26 92.1 16.7 3.8e-26 91.8 11.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF212 PF02681.9 EQC53017.1 - 0.073 12.7 0.8 0.097 12.3 0.6 1.2 1 0 0 1 1 1 0 Divergent PAP2 family DUF212 PF02681.9 EQC53018.1 - 0.0085 15.8 1.0 0.012 15.3 0.7 1.3 1 0 0 1 1 1 1 Divergent PAP2 family Cut8_C PF08559.5 EQC53021.1 - 0.024 14.4 1.7 0.038 13.8 1.2 1.3 1 0 0 1 1 1 0 Cut8 six-helix bundle tRNA-synt_1g PF09334.6 EQC53023.1 - 6.7e-85 285.0 2.8 5.2e-51 173.5 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EQC53023.1 - 1.6e-18 66.1 0.0 3.4e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EQC53023.1 - 2.2e-06 27.0 0.6 7.6e-05 21.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EQC53023.1 - 0.01 14.5 0.2 0.026 13.2 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (K) Chromo PF00385.19 EQC53024.1 - 2.2e-13 49.6 2.8 2.4e-13 49.5 1.9 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pga1 PF10333.4 EQC53025.1 - 0.0041 16.7 1.0 0.0068 16.0 0.1 1.6 1 1 0 2 2 2 1 GPI-Mannosyltransferase II co-activator B12D PF06522.6 EQC53027.1 - 0.061 13.0 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PIG-Y PF15159.1 EQC53028.1 - 0.00018 21.6 7.2 0.00023 21.3 5.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2638 PF10937.3 EQC53029.1 - 8.8e-07 29.9 1.1 9.2e-06 26.6 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2638) DASH_Duo1 PF08651.5 EQC53030.1 - 0.0025 17.3 0.2 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3552 PF12072.3 EQC53030.1 - 0.038 13.2 1.5 0.045 12.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) bZIP_2 PF07716.10 EQC53030.1 - 0.038 13.8 2.9 0.054 13.3 2.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF2802 PF10975.3 EQC53030.1 - 0.11 12.2 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF536 PF04394.9 EQC53030.1 - 0.37 10.5 3.4 0.62 9.8 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Pro_CA PF00484.14 EQC53032.1 - 1.2e-47 161.7 0.1 1.9e-47 161.0 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF3018 PF11455.3 EQC53032.1 - 0.062 13.2 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Ribosomal_L4 PF00573.17 EQC53033.1 - 2.4e-44 151.0 2.8 3.6e-44 150.4 1.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EQC53033.1 - 1.7e-26 91.8 4.3 1.7e-26 91.8 3.0 2.4 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Rpp20 PF12328.3 EQC53034.1 - 2.8e-10 39.9 0.5 1.3e-09 37.8 0.4 1.7 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Bac_DnaA PF00308.13 EQC53034.1 - 0.07 12.7 0.2 0.084 12.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial dnaA protein APG12 PF04110.8 EQC53036.1 - 3e-30 104.2 0.1 4.1e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EQC53036.1 - 0.00042 20.2 0.0 0.00053 19.9 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like PUF PF00806.14 EQC53037.1 - 8.1e-19 65.9 0.0 0.0011 18.3 0.0 5.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EQC53037.1 - 2.1e-11 43.3 0.0 4.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EQC53037.1 - 1.7e-10 40.7 0.0 4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EQC53037.1 - 1.7e-09 37.3 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGT PF01702.13 EQC53038.1 - 8.3e-33 113.6 0.1 1.2e-30 106.5 0.1 2.3 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Phosducin PF02114.11 EQC53038.1 - 3.4e-10 39.0 0.3 5.8e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EQC53038.1 - 2.3e-06 27.2 0.2 5.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin TBPIP PF07106.8 EQC53039.1 - 0.0044 16.5 9.9 0.36 10.3 2.8 2.4 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BAR_2 PF10455.4 EQC53039.1 - 0.016 14.1 5.2 0.016 14.1 3.0 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DivIC PF04977.10 EQC53039.1 - 0.034 13.6 1.1 0.034 13.6 0.7 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF720 PF05302.6 EQC53039.1 - 0.039 13.7 1.2 0.059 13.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Prefoldin_3 PF13758.1 EQC53039.1 - 0.048 13.4 3.1 0.089 12.5 1.8 1.8 1 1 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.6 EQC53039.1 - 0.063 13.1 4.5 0.099 12.5 0.6 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Streptin-Immun PF11083.3 EQC53039.1 - 0.088 12.8 5.0 4.7 7.2 0.1 2.8 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein HALZ PF02183.13 EQC53039.1 - 0.088 12.5 1.0 0.088 12.5 0.7 4.2 3 1 2 5 5 5 0 Homeobox associated leucine zipper DUF4363 PF14276.1 EQC53039.1 - 0.12 12.0 4.2 0.9 9.2 2.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) DUF972 PF06156.8 EQC53039.1 - 0.15 12.4 10.9 0.22 11.9 3.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EQC53039.1 - 0.16 11.9 10.9 0.083 12.8 1.2 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF3573 PF12097.3 EQC53039.1 - 0.17 10.4 1.4 0.2 10.2 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3287 PF11690.3 EQC53039.1 - 0.19 11.8 6.8 1.4 9.0 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF722 PF05263.6 EQC53039.1 - 0.25 11.4 4.1 0.3 11.2 2.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF722) GBP_C PF02841.9 EQC53039.1 - 0.37 9.9 9.5 1.2 8.2 6.5 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF904 PF06005.7 EQC53039.1 - 0.38 11.0 14.9 21 5.4 7.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Apolipoprotein PF01442.13 EQC53039.1 - 0.43 10.0 9.9 0.75 9.2 6.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain RRP7 PF12923.2 EQC53039.1 - 0.46 10.5 4.0 4.4 7.3 2.8 2.1 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DASH_Hsk3 PF08227.6 EQC53039.1 - 0.48 10.6 4.0 2.4 8.3 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like TMPIT PF07851.8 EQC53039.1 - 0.69 8.9 4.2 0.85 8.6 2.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.6 EQC53039.1 - 0.75 10.2 4.8 1.8 8.9 1.8 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_S PF02609.11 EQC53039.1 - 0.83 9.4 6.4 0.56 10.0 0.1 3.6 3 2 0 3 3 3 0 Exonuclease VII small subunit Atg14 PF10186.4 EQC53039.1 - 0.85 8.5 12.4 0.66 8.8 6.2 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 EQC53039.1 - 0.98 9.4 9.6 1.2 9.1 3.1 2.3 1 1 1 2 2 2 0 DivIVA protein V_ATPase_I PF01496.14 EQC53039.1 - 1.1 7.0 6.3 1.3 6.7 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 EQC53039.1 - 1.1 8.9 14.0 0.11 12.2 2.1 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EQC53039.1 - 1.5 9.0 11.3 0.41 10.8 2.8 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGAP_C PF03836.10 EQC53039.1 - 1.5 8.4 11.2 54 3.4 7.8 2.4 1 1 0 1 1 1 0 RasGAP C-terminus HalX PF08663.5 EQC53039.1 - 2.2 8.3 8.5 0.28 11.1 0.5 3.0 2 2 2 4 4 4 0 HalX domain Spc7 PF08317.6 EQC53039.1 - 2.3 6.7 12.6 0.45 9.1 3.2 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 EQC53039.1 - 2.6 7.1 9.7 3.1 6.8 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 EQC53039.1 - 2.9 7.7 15.5 38 4.1 10.5 2.6 1 1 0 1 1 1 0 Tropomyosin like Kinetocho_Slk19 PF12709.2 EQC53039.1 - 4.5 7.4 13.2 17 5.6 3.4 2.8 1 1 1 2 2 2 0 Central kinetochore-associated OmpH PF03938.9 EQC53039.1 - 4.5 7.1 7.7 42 4.0 5.4 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.12 EQC53039.1 - 5.2 7.4 11.6 5.7 7.3 0.3 3.2 1 1 1 3 3 3 0 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 EQC53039.1 - 5.6 6.7 14.3 0.092 12.4 4.0 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.6 EQC53039.1 - 8.1 6.2 8.3 1.3 8.8 1.7 2.6 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ArsD PF06953.6 EQC53042.1 - 0.0024 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Arsenical resistance operon trans-acting repressor ArsD DUF2358 PF10184.4 EQC53042.1 - 0.013 15.4 0.2 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Ribosomal_L30 PF00327.15 EQC53043.1 - 1.4e-08 34.1 0.0 2.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Retrotrans_gag PF03732.12 EQC53044.1 - 4e-08 33.2 0.1 9.3e-08 32.0 0.1 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein DUF2785 PF10978.3 EQC53044.1 - 0.031 13.7 0.3 2 7.8 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2785) PepSY_TM_2 PF13703.1 EQC53044.1 - 0.088 12.9 0.5 0.088 12.9 0.3 1.6 2 0 0 2 2 2 0 PepSY-associated TM helix Zn_clus PF00172.13 EQC53045.1 - 1e-06 28.5 13.2 2.2e-06 27.4 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reo_sigmaC PF04582.7 EQC53049.1 - 0.011 14.8 3.4 0.022 13.9 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EQC53049.1 - 1.9 7.0 30.2 1.2 7.6 11.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EQC53049.1 - 4.4 7.0 26.9 24 4.6 1.6 3.7 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SAP18 PF06487.7 EQC53050.1 - 2.7e-20 72.3 0.0 3.2e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) MA3 PF02847.12 EQC53051.1 - 0.055 13.1 0.1 0.17 11.5 0.1 1.8 1 1 1 2 2 2 0 MA3 domain TPR_3 PF07720.7 EQC53051.1 - 0.93 9.3 5.4 0.35 10.7 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C48 PF02902.14 EQC53052.1 - 1.3e-20 73.9 0.0 3.2e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cyclin PF08613.6 EQC53053.1 - 3.9e-32 111.7 0.4 4.9e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 Cyclin Telomerase_RBD PF12009.3 EQC53054.1 - 3.8e-38 130.4 4.0 1.3e-37 128.7 2.8 2.0 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EQC53054.1 - 8.6e-13 48.1 0.2 4.2e-12 45.8 0.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B12D PF06522.6 EQC53055.1 - 2.9e-07 30.0 0.0 3.2e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Adeno_PX PF05829.7 EQC53055.1 - 0.03 13.7 1.0 0.04 13.3 0.7 1.2 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) IL12p40_C PF10420.4 EQC53056.1 - 2.2 8.4 5.4 15 5.7 0.7 2.4 1 1 1 2 2 2 0 Cytokine interleukin-12p40 C-terminus RNase_H PF00075.19 EQC53057.1 - 3.5e-30 105.0 0.0 6.5e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EQC53057.1 - 3.5e-19 68.5 2.1 7.1e-19 67.5 1.5 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Complex1_LYR PF05347.10 EQC53059.1 - 1.2 8.9 5.6 0.21 11.3 0.5 2.2 2 1 0 2 2 2 0 Complex 1 protein (LYR family) DUF3767 PF12597.3 EQC53060.1 - 2.8e-20 72.1 0.1 3.4e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) RNB PF00773.14 EQC53061.1 - 8.1e-55 186.3 0.0 1.4e-54 185.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain Inhibitor_I78 PF11720.3 EQC53063.1 - 1.4e-11 43.9 0.1 1.8e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EQC53063.1 - 0.084 13.0 0.2 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Potato inhibitor I family Baculo_PEP_C PF04513.7 EQC53065.1 - 0.19 11.5 1.2 0.32 10.8 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.4 EQC53065.1 - 0.2 11.2 1.0 1.3 8.6 0.5 2.3 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Rgp1 PF08737.5 EQC53066.1 - 1.9e-28 99.6 0.0 9.6e-28 97.3 0.0 1.9 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EQC53066.1 - 0.013 15.3 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Hpt PF01627.18 EQC53068.1 - 9.1e-12 44.8 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Hpt domain AP_endonuc_2 PF01261.19 EQC53068.1 - 0.00095 18.5 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UPF0139 PF03669.8 EQC53070.1 - 0.00095 18.6 1.1 0.001 18.5 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Hexapep PF00132.19 EQC53071.1 - 4.9e-15 54.2 11.0 3.2e-12 45.3 3.8 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EQC53071.1 - 6.5e-14 51.6 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EQC53071.1 - 1.2e-11 43.9 13.3 1e-10 40.9 2.9 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2613 PF11021.3 EQC53071.1 - 0.28 10.9 4.6 0.52 10.0 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Cmc1 PF08583.5 EQC53074.1 - 2.3e-15 56.0 4.3 2.7e-15 55.8 2.9 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EQC53074.1 - 0.00044 19.5 2.7 0.0006 19.1 1.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.8 EQC53074.1 - 0.0078 16.2 3.3 1.2 9.1 0.4 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) ATG16 PF08614.6 EQC53074.1 - 0.014 15.1 0.3 0.015 15.1 0.2 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CHCH PF06747.8 EQC53074.1 - 0.019 14.9 2.4 0.032 14.1 1.7 1.4 1 0 0 1 1 1 0 CHCH domain Mre11_DNA_bind PF04152.9 EQC53075.1 - 1.1e-55 188.2 0.2 1.1e-55 188.2 0.1 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EQC53075.1 - 1.6e-29 102.7 2.1 2.3e-29 102.2 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EQC53075.1 - 4.5e-06 26.5 0.2 2.4e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sporozoite_P67 PF05642.6 EQC53075.1 - 0.0046 14.8 3.2 0.0065 14.4 2.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AKAP95 PF04988.7 EQC53075.1 - 2.1 8.0 6.4 1.4 8.7 0.5 2.7 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Ku_N PF03731.10 EQC53076.1 - 8.8e-41 139.7 0.0 1.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EQC53076.1 - 1.1e-34 119.5 0.0 2.3e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EQC53076.1 - 3.2e-11 43.5 0.0 1.5e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EQC53076.1 - 1.6e-09 37.0 0.0 3.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EQC53076.1 - 3.3e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3505 PF12013.3 EQC53077.1 - 2e-05 24.7 2.9 0.006 16.8 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3505) zf-met PF12874.2 EQC53077.1 - 0.00039 20.5 8.6 0.0037 17.4 0.9 3.5 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EQC53077.1 - 0.011 15.8 2.7 0.011 15.8 1.8 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding P53_tetramer PF07710.6 EQC53077.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 P53 tetramerisation motif zf-C2H2_4 PF13894.1 EQC53077.1 - 0.81 10.1 23.5 0.27 11.6 2.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.7 EQC53077.1 - 2.9 6.3 11.1 0.64 8.4 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF629)